Guide to the Human Genome
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Search of human proteins with 110224476

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110224476 prosaposin isoform b preproprotein [Homo sapiens]
         (527 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110224476 prosaposin isoform b preproprotein [Homo sapiens]       1085   0.0  
gi|110224479 prosaposin isoform c preproprotein [Homo sapiens]       1078   0.0  
gi|11386147 prosaposin isoform a preproprotein [Homo sapiens]        1073   0.0  
gi|145977198 prosaposin-like protein 1 [Homo sapiens]                 451   e-126
gi|38504667 surfactant, pulmonary-associated protein B [Homo sap...    99   7e-21
gi|33943099 surfactant, pulmonary-associated protein B [Homo sap...    99   7e-21
gi|4502115 acyloxyacyl hydrolase precursor [Homo sapiens]              40   0.004
gi|221219048 transducin-like enhancer protein 2 isoform 2 [Homo ...    35   0.17 
gi|21361151 transducin-like enhancer protein 2 isoform 1 [Homo s...    35   0.22 
gi|5453634 dynein, cytoplasmic, light intermediate polypeptide 2...    34   0.38 
gi|156139127 hypothetical protein LOC80007 [Homo sapiens]              34   0.38 
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         32   1.1  
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         32   1.1  
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]               32   1.1  
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]               32   1.1  
gi|41281907 StAR-related lipid transfer (START) domain containin...    32   1.9  
gi|7657671 upstream binding transcription factor, RNA polymerase...    32   1.9  
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             32   1.9  
gi|29788760 diacylglycerol kinase, eta isoform 1 [Homo sapiens]        31   2.4  
gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens]        31   2.4  
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo...    31   2.4  
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ...    31   3.2  
gi|24475849 hypothetical protein LOC203228 isoform b [Homo sapiens]    31   3.2  
gi|37039612 hypothetical protein LOC203228 isoform a [Homo sapiens]    31   3.2  
gi|39812027 amino-terminal enhancer of split isoform c [Homo sap...    31   3.2  
gi|7706254 NOP58 ribonucleoprotein homolog [Homo sapiens]              30   4.2  
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]       30   5.4  
gi|7108344 granulysin isoform NKG5 [Homo sapiens]                      30   5.4  
gi|157502222 granulysin isoform 519 [Homo sapiens]                     30   5.4  
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]        30   5.4  

>gi|110224476 prosaposin isoform b preproprotein [Homo sapiens]
          Length = 527

 Score = 1085 bits (2805), Expect = 0.0
 Identities = 527/527 (100%), Positives = 527/527 (100%)

Query: 1   MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS 60
           MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS
Sbjct: 1   MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS 60

Query: 61  LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI 120
           LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI
Sbjct: 61  LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI 120

Query: 121 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY 180
           IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY
Sbjct: 121 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY 180

Query: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240
           PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI
Sbjct: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240

Query: 241 CKNYISQYSEIAIQMMMHMQDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALE 300
           CKNYISQYSEIAIQMMMHMQDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALE
Sbjct: 241 CKNYISQYSEIAIQMMMHMQDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALE 300

Query: 301 LVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEEC 360
           LVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEEC
Sbjct: 301 LVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEEC 360

Query: 361 QEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVG 420
           QEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVG
Sbjct: 361 QEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVG 420

Query: 421 YLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCL 480
           YLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCL
Sbjct: 421 YLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCL 480

Query: 481 KIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 527
           KIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN
Sbjct: 481 KIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 527


>gi|110224479 prosaposin isoform c preproprotein [Homo sapiens]
          Length = 526

 Score = 1078 bits (2788), Expect = 0.0
 Identities = 526/527 (99%), Positives = 526/527 (99%), Gaps = 1/527 (0%)

Query: 1   MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS 60
           MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS
Sbjct: 1   MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS 60

Query: 61  LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI 120
           LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI
Sbjct: 61  LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI 120

Query: 121 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY 180
           IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY
Sbjct: 121 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY 180

Query: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240
           PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI
Sbjct: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240

Query: 241 CKNYISQYSEIAIQMMMHMQDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALE 300
           CKNYISQYSEIAIQMMMHM DQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALE
Sbjct: 241 CKNYISQYSEIAIQMMMHM-DQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALE 299

Query: 301 LVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEEC 360
           LVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEEC
Sbjct: 300 LVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEEC 359

Query: 361 QEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVG 420
           QEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVG
Sbjct: 360 QEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVG 419

Query: 421 YLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCL 480
           YLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCL
Sbjct: 420 YLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCL 479

Query: 481 KIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 527
           KIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN
Sbjct: 480 KIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 526


>gi|11386147 prosaposin isoform a preproprotein [Homo sapiens]
          Length = 524

 Score = 1073 bits (2775), Expect = 0.0
 Identities = 524/527 (99%), Positives = 524/527 (99%), Gaps = 3/527 (0%)

Query: 1   MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS 60
           MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS
Sbjct: 1   MYALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKS 60

Query: 61  LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI 120
           LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI
Sbjct: 61  LPCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDI 120

Query: 121 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY 180
           IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY
Sbjct: 121 IKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLY 180

Query: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240
           PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI
Sbjct: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240

Query: 241 CKNYISQYSEIAIQMMMHMQDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALE 300
           CKNYISQYSEIAIQMMMHMQ   PKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALE
Sbjct: 241 CKNYISQYSEIAIQMMMHMQ---PKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALE 297

Query: 301 LVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEEC 360
           LVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEEC
Sbjct: 298 LVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEEC 357

Query: 361 QEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVG 420
           QEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVG
Sbjct: 358 QEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVG 417

Query: 421 YLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCL 480
           YLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCL
Sbjct: 418 YLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVCL 477

Query: 481 KIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 527
           KIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN
Sbjct: 478 KIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 524


>gi|145977198 prosaposin-like protein 1 [Homo sapiens]
          Length = 521

 Score =  451 bits (1159), Expect = e-126
 Identities = 236/535 (44%), Positives = 334/535 (62%), Gaps = 39/535 (7%)

Query: 3   ALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLP 62
           AL LL SLLGA  A P  G +EC +GS VWCQ+++TA+ CGAV +C   VWNKPT KSLP
Sbjct: 4   ALLLLPSLLGATRASPTSGPQECAKGSTVWCQDLQTAARCGAVGYCQGAVWNKPTAKSLP 63

Query: 63  CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
           CD+C+D+  AAG+ L  +ATE +IL  + KTC+WLP    SA CK +VD++   IL +++
Sbjct: 64  CDVCQDIAAAAGNGLNPDATESDILALVMKTCEWLPSQESSAGCKWMVDAHSSAILSMLR 123

Query: 123 GEM-SRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLYP 181
           G   S P +VC+AL+LCE LQ+HLA L          + + D  E VAPFMAN PL  +P
Sbjct: 124 GAPDSAPAQVCTALSLCEPLQRHLATLR--------PLSKEDTFEAVAPFMANGPLTFHP 175

Query: 182 QDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADIC 241
           +  P         G +CQDC++ V+ +Q AVR+N T       +++E+C+ LGPG+A +C
Sbjct: 176 RQAPE--------GALCQDCVRQVSRLQEAVRSNLTLADL---NIQEQCESLGPGLAVLC 224

Query: 242 KNYISQYSEIAIQMMMHMQDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALEL 301
           KNY+ Q+   A Q +  +    P+E+C   GFC+E+      T    +V + + +P+LEL
Sbjct: 225 KNYLFQFFVPADQALRLLP---PQELCRKGGFCEELGAPARLT----QVVAMDGVPSLEL 277

Query: 302 VEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQ 361
             P K+ E+  K+ V CEVC  +V+++   + +N +E  I  A +++CS +P S+++EC 
Sbjct: 278 GLPRKQSEMQMKAGVTCEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECI 337

Query: 362 EVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVH-----VTQPK-----DGGF 411
            +VDTY  S++  L+ +++PE VC  + LC G R  A  VH     V  P+      G F
Sbjct: 338 ILVDTYSPSLVQ-LVAKITPEKVCKFIRLC-GNRRRARAVHDAYAIVPSPEWDAENQGSF 395

Query: 412 CEVCKKLVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVE 471
           C  CK+L+     NLE  STK++IL A + GCS LP PY  QC  FV +YEPVLIE L +
Sbjct: 396 CNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKD 455

Query: 472 VMDPSFVCLKIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVW 526
           +MDP  VC K+GAC     PLLGT++C  GPS+WC++ E A  CNAV+HC++HVW
Sbjct: 456 MMDPVAVCKKVGACHGPRTPLLGTDQCALGPSFWCRSQEAAKLCNAVQHCQKHVW 510



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 17/37 (45%), Positives = 25/37 (67%)

Query: 491 PLLGTEKCIWGPSYWCQNTETAAQCNAVEHCKRHVWN 527
           P  G ++C  G + WCQ+ +TAA+C AV +C+  VWN
Sbjct: 19  PTSGPQECAKGSTVWCQDLQTAARCGAVGYCQGAVWN 55



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 15/38 (39%), Positives = 24/38 (63%)

Query: 18  PVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNK 55
           P+LG  +C  G + WC++ + A  C AV+HC + VW +
Sbjct: 475 PLLGTDQCALGPSFWCRSQEAAKLCNAVQHCQKHVWKE 512


>gi|38504667 surfactant, pulmonary-associated protein B [Homo
           sapiens]
          Length = 381

 Score = 99.4 bits (246), Expect = 7e-21
 Identities = 91/412 (22%), Positives = 164/412 (39%), Gaps = 54/412 (13%)

Query: 2   YALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSL 61
           + L LL +L G   A        C +G   WCQ+++ A  C A+ HCLQ VW       L
Sbjct: 9   WLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHVGADDL 68

Query: 62  PCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDII 121
            C  C+D+V     M K+   ++ +  +LE+ C+ LP   +   C +++D Y P+++D  
Sbjct: 69  -CQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYF 127

Query: 122 KGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLYP 181
           + +    G +C  L LC+S Q        Q+   S+ +P+     +  P +  + L + P
Sbjct: 128 QNQTDSNG-ICMHLGLCKSRQPE----PEQEPGMSDPLPKPLRDPLPDPLLDKLVLPVLP 182

Query: 182 -----QDGPRSKPQPKDNGDV----CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDR 232
                + GP ++   +    +    C  C  ++  IQ  +        AL   V + C  
Sbjct: 183 GALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKG-----ALAVAVAQVCRV 237

Query: 233 LGPGMADICKNYISQYSEIAIQMMMHMQDQQPKEICALVGFCDEVKEMPMQTLVPAKVAS 292
           +      IC+    +YS I +  ++      P+ +C LV  C       M      +  +
Sbjct: 238 VPLVAGGICQCLAERYSVILLDTLLGR--MLPQLVCRLVLRCS------MDDSAGPRSPT 289

Query: 293 KNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMC--S 350
              +P                 D  C +C  +  +       N +E+ I  A  + C  S
Sbjct: 290 GEWLP----------------RDSECHLCMSVTTQA-----GNSSEQAIPQAMLQACVGS 328

Query: 351 KLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVH 402
            L +   E+C++ V+ +   +L+++         C  L +C     P   +H
Sbjct: 329 WLDR---EKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMSSPLQCIH 377



 Score = 72.8 bits (177), Expect = 7e-13
 Identities = 75/335 (22%), Positives = 135/335 (40%), Gaps = 50/335 (14%)

Query: 196 DVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMA-DICKNYISQYSEIAIQ 254
           D+CQ+C  +V  I   +   + F   + + +++EC+ L   +    C   +  Y  + I 
Sbjct: 67  DLCQECEDIV-HILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVID 125

Query: 255 MMMHMQDQQPKEICALVGFC-------------DEVKEMPMQTLVPAKVASKNVIPALEL 301
              +  D     IC  +G C              +    P++  +P  +  K V+P L  
Sbjct: 126 YFQNQTDSNG--ICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPLPDPLLDKLVLPVLP- 182

Query: 302 VEPIKKHEVPAKSDV----------YCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSK 351
              ++    P   D+          YC +C  L+K +  +I        +  A  ++C  
Sbjct: 183 -GALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGA----LAVAVAQVCRV 237

Query: 352 LPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS--GTRLPALTVHVTQPKDG 409
           +P      CQ + + Y   +L  LL  + P+LVC ++  CS   +  P        P+D 
Sbjct: 238 VPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDS 297

Query: 410 GFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGC--SFLPDPYQKQCDQFVAEYEPVLIE 467
             C +C  +          NS++Q I  A+ + C  S+L    +++C QFV ++ P L+ 
Sbjct: 298 E-CHLCMSVT-----TQAGNSSEQAIPQAMLQACVGSWLD---REKCKQFVEQHTPQLLT 348

Query: 468 ILVEVMDPSFVCLKIGACPSAHKPLLGTEKCIWGP 502
           ++    D    C  +G C +   PL    +CI  P
Sbjct: 349 LVPRGWDAHTTCQALGVCGTMSSPL----QCIHSP 379



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 15/29 (51%), Positives = 19/29 (65%)

Query: 498 CIWGPSYWCQNTETAAQCNAVEHCKRHVW 526
           C  GP +WCQ+ E A QC A+ HC + VW
Sbjct: 32  CAQGPEFWCQSLEQALQCRALGHCLQEVW 60


>gi|33943099 surfactant, pulmonary-associated protein B [Homo
           sapiens]
          Length = 381

 Score = 99.4 bits (246), Expect = 7e-21
 Identities = 91/412 (22%), Positives = 164/412 (39%), Gaps = 54/412 (13%)

Query: 2   YALFLLASLLGAALAGPVLGLKECTRGSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSL 61
           + L LL +L G   A        C +G   WCQ+++ A  C A+ HCLQ VW       L
Sbjct: 9   WLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHVGADDL 68

Query: 62  PCDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDII 121
            C  C+D+V     M K+   ++ +  +LE+ C+ LP   +   C +++D Y P+++D  
Sbjct: 69  -CQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYF 127

Query: 122 KGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLYP 181
           + +    G +C  L LC+S Q        Q+   S+ +P+     +  P +  + L + P
Sbjct: 128 QNQTDSNG-ICMHLGLCKSRQPE----PEQEPGMSDPLPKPLRDPLPDPLLDKLVLPVLP 182

Query: 182 -----QDGPRSKPQPKDNGDV----CQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDR 232
                + GP ++   +    +    C  C  ++  IQ  +        AL   V + C  
Sbjct: 183 GALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKG-----ALAVAVAQVCRV 237

Query: 233 LGPGMADICKNYISQYSEIAIQMMMHMQDQQPKEICALVGFCDEVKEMPMQTLVPAKVAS 292
           +      IC+    +YS I +  ++      P+ +C LV  C       M      +  +
Sbjct: 238 VPLVAGGICQCLAERYSVILLDTLLGR--MLPQLVCRLVLRCS------MDDSAGPRSPT 289

Query: 293 KNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMC--S 350
              +P                 D  C +C  +  +       N +E+ I  A  + C  S
Sbjct: 290 GEWLP----------------RDSECHLCMSVTTQA-----GNSSEQAIPQAMLQACVGS 328

Query: 351 KLPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVH 402
            L +   E+C++ V+ +   +L+++         C  L +C     P   +H
Sbjct: 329 WLDR---EKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMSSPLQCIH 377



 Score = 72.8 bits (177), Expect = 7e-13
 Identities = 75/335 (22%), Positives = 135/335 (40%), Gaps = 50/335 (14%)

Query: 196 DVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMA-DICKNYISQYSEIAIQ 254
           D+CQ+C  +V  I   +   + F   + + +++EC+ L   +    C   +  Y  + I 
Sbjct: 67  DLCQECEDIV-HILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVID 125

Query: 255 MMMHMQDQQPKEICALVGFC-------------DEVKEMPMQTLVPAKVASKNVIPALEL 301
              +  D     IC  +G C              +    P++  +P  +  K V+P L  
Sbjct: 126 YFQNQTDSNG--ICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPLPDPLLDKLVLPVLP- 182

Query: 302 VEPIKKHEVPAKSDV----------YCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSK 351
              ++    P   D+          YC +C  L+K +  +I        +  A  ++C  
Sbjct: 183 -GALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGA----LAVAVAQVCRV 237

Query: 352 LPKSLSEECQEVVDTYGSSILSILLEEVSPELVCSMLHLCS--GTRLPALTVHVTQPKDG 409
           +P      CQ + + Y   +L  LL  + P+LVC ++  CS   +  P        P+D 
Sbjct: 238 VPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDS 297

Query: 410 GFCEVCKKLVGYLDRNLEKNSTKQEILAALEKGC--SFLPDPYQKQCDQFVAEYEPVLIE 467
             C +C  +          NS++Q I  A+ + C  S+L    +++C QFV ++ P L+ 
Sbjct: 298 E-CHLCMSVT-----TQAGNSSEQAIPQAMLQACVGSWLD---REKCKQFVEQHTPQLLT 348

Query: 468 ILVEVMDPSFVCLKIGACPSAHKPLLGTEKCIWGP 502
           ++    D    C  +G C +   PL    +CI  P
Sbjct: 349 LVPRGWDAHTTCQALGVCGTMSSPL----QCIHSP 379



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 15/29 (51%), Positives = 19/29 (65%)

Query: 498 CIWGPSYWCQNTETAAQCNAVEHCKRHVW 526
           C  GP +WCQ+ E A QC A+ HC + VW
Sbjct: 32  CAQGPEFWCQSLEQALQCRALGHCLQEVW 60


>gi|4502115 acyloxyacyl hydrolase precursor [Homo sapiens]
          Length = 575

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 6/77 (7%)

Query: 318 CEVCEFLVKEVTKLID-NNKTEKEILDAFDKMCSKLPKSL--SEECQEVVDTYGSSILSI 374
           C  C  +V  + +L   +N T   +  + +++CS LP+ L     C  V+D +GS I+ +
Sbjct: 41  CVGCVLVVSVIEQLAQVHNST---VQASMERLCSYLPEKLFLKTTCYLVIDKFGSDIIKL 97

Query: 375 LLEEVSPELVCSMLHLC 391
           L  +++ ++VC  L  C
Sbjct: 98  LSADMNADVVCHTLEFC 114



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 25/109 (22%), Positives = 48/109 (44%), Gaps = 8/109 (7%)

Query: 181 PQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPG--MA 238
           P +  +S+P    NG  C  C+ +V+ I+   + +++ VQA +E +   C  L     + 
Sbjct: 25  PANDDQSRPS-LSNGHTCVGCVLVVSVIEQLAQVHNSTVQASMERL---CSYLPEKLFLK 80

Query: 239 DICKNYISQYSEIAIQMMMHMQDQQPKEICALVGFCDEVKEMPMQTLVP 287
             C   I ++    I+++    D     +C  + FC +    P+  L P
Sbjct: 81  TTCYLVIDKFGSDIIKLL--SADMNADVVCHTLEFCKQNTGQPLCHLYP 127


>gi|221219048 transducin-like enhancer protein 2 isoform 2 [Homo
           sapiens]
          Length = 706

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 34/140 (24%), Positives = 61/140 (43%), Gaps = 13/140 (9%)

Query: 182 QDGPRSKPQ-PKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADI 240
           QD P S  Q P  +G   +  I  + D    ++    F+QA    +K EC++L     ++
Sbjct: 13  QDSPASGLQTPLQSGQPFKFSILEICD---RIKEEFQFLQAQYHSLKLECEKLASEKTEM 69

Query: 241 CKNYISQYS-EIAIQMMMHMQDQQPKE---ICALV--GFCDEVKEMPMQTLVPAK---VA 291
            ++Y+  Y     + + MH Q +  K    ICA +      E ++  +Q +  AK   V 
Sbjct: 70  QRHYVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVG 129

Query: 292 SKNVIPALELVEPIKKHEVP 311
             N +   + ++P+  H  P
Sbjct: 130 ELNSLIGQQQLQPLSHHAPP 149


>gi|21361151 transducin-like enhancer protein 2 isoform 1 [Homo
           sapiens]
          Length = 743

 Score = 34.7 bits (78), Expect = 0.22
 Identities = 32/141 (22%), Positives = 62/141 (43%), Gaps = 14/141 (9%)

Query: 179 LYPQDGPRSKPQPKDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMA 238
           +YPQ      P P  +G   +  I  + D    ++    F+QA    +K EC++L     
Sbjct: 1   MYPQG---RHPTPLQSGQPFKFSILEICD---RIKEEFQFLQAQYHSLKLECEKLASEKT 54

Query: 239 DICKNYISQYS-EIAIQMMMHMQDQQPKE---ICALV--GFCDEVKEMPMQTLVPAKVAS 292
           ++ ++Y+  Y     + + MH Q +  K    ICA +      E ++  +Q +  AK  +
Sbjct: 55  EMQRHYVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVT 114

Query: 293 KNVIPAL--ELVEPIKKHEVP 311
              + +L  + ++P+  H  P
Sbjct: 115 VGELNSLIGQQLQPLSHHAPP 135


>gi|5453634 dynein, cytoplasmic, light intermediate polypeptide 2
           [Homo sapiens]
          Length = 492

 Score = 33.9 bits (76), Expect = 0.38
 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 8/77 (10%)

Query: 114 LPVILDIIKGEMSRPGEVCSALNLCESLQKHLAELNHQKQLESNKIPELDMTEVVAPFMA 173
           LP  L I   +MSRP  V       ESLQK  + L  ++ ++  KIP   M E+   F+ 
Sbjct: 128 LPETLVIFVADMSRPWTVM------ESLQKWASVL--REHIDKMKIPPEKMRELERKFVK 179

Query: 174 NIPLLLYPQDGPRSKPQ 190
           +    + P++G +  PQ
Sbjct: 180 DFQDYMEPEEGCQGSPQ 196


>gi|156139127 hypothetical protein LOC80007 [Homo sapiens]
          Length = 445

 Score = 33.9 bits (76), Expect = 0.38
 Identities = 29/119 (24%), Positives = 52/119 (43%), Gaps = 23/119 (19%)

Query: 313 KSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSK---LPKSLSEECQEVVDTYGS 369
           ++D+   +  FL K+V+   ++N    E+L     +CS+   L      ECQE +  +G 
Sbjct: 305 ENDLKNAMASFLPKKVSD--NSNIPNSELLPFLQNLCSQVNHLHVGNKTECQENITKHGE 362

Query: 370 SILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEK 428
            IL + +EE S   +CS L       +  +                KKL+ Y+D+ + +
Sbjct: 363 RILGVGMEEQS---ICSYLEKILSKNMELME---------------KKLMDYIDQRIHE 403


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 55/257 (21%), Positives = 103/257 (40%), Gaps = 24/257 (9%)

Query: 141  LQKHLAELNHQKQLESNKIPEL-DMTEVVAPFMANIPLLLYPQDGPRSKPQP-------- 191
            LQ+  A+L  +  +  ++   L DM ++  P      L+       +SK           
Sbjct: 766  LQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEIL 825

Query: 192  -KDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVE----HVKEECDRLGPGMADICKNYIS 246
             ++N D+ Q CIQ+  +I+   R   +F +   E     ++EE   L     D+  +   
Sbjct: 826  IEENEDLKQQCIQLNEEIEKQ-RNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNK 884

Query: 247  QYSEI-----AIQMMMHMQDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALEL 301
            Q  E      A+   +H+Q   P  +       DE K    +TL   +V  K+    +E 
Sbjct: 885  QELEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEK 944

Query: 302  VEPIKKHEVPAKSDVYCEVCEFLVK---EVTKLIDNNKTEKEILDAFDKMCSKLPKSLSE 358
            +E + K E    S    ++ E L +   E++ L +  K+ K+  +     C +L   ++ 
Sbjct: 945  LE-VTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINH 1003

Query: 359  ECQEVVDTYGSSILSIL 375
               E V +  + + S+L
Sbjct: 1004 NRAENVQSCDTQVSSLL 1020


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 55/257 (21%), Positives = 103/257 (40%), Gaps = 24/257 (9%)

Query: 141  LQKHLAELNHQKQLESNKIPEL-DMTEVVAPFMANIPLLLYPQDGPRSKPQP-------- 191
            LQ+  A+L  +  +  ++   L DM ++  P      L+       +SK           
Sbjct: 766  LQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEIL 825

Query: 192  -KDNGDVCQDCIQMVTDIQTAVRTNSTFVQALVE----HVKEECDRLGPGMADICKNYIS 246
             ++N D+ Q CIQ+  +I+   R   +F +   E     ++EE   L     D+  +   
Sbjct: 826  IEENEDLKQQCIQLNEEIEKQ-RNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNK 884

Query: 247  QYSEI-----AIQMMMHMQDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALEL 301
            Q  E      A+   +H+Q   P  +       DE K    +TL   +V  K+    +E 
Sbjct: 885  QELEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEK 944

Query: 302  VEPIKKHEVPAKSDVYCEVCEFLVK---EVTKLIDNNKTEKEILDAFDKMCSKLPKSLSE 358
            +E + K E    S    ++ E L +   E++ L +  K+ K+  +     C +L   ++ 
Sbjct: 945  LE-VTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINH 1003

Query: 359  ECQEVVDTYGSSILSIL 375
               E V +  + + S+L
Sbjct: 1004 NRAENVQSCDTQVSSLL 1020


>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
          Length = 1184

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 2/42 (4%)

Query: 480 LKIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHC 521
           LK G C    +  +GT  C   P + CQNT+ +  C A + C
Sbjct: 757 LKDGECEDVDECAMGTHTC--QPGFLCQNTKGSFYCQARQRC 796


>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
          Length = 1231

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 2/42 (4%)

Query: 480 LKIGACPSAHKPLLGTEKCIWGPSYWCQNTETAAQCNAVEHC 521
           LK G C    +  +GT  C   P + CQNT+ +  C A + C
Sbjct: 804 LKDGECEDVDECAMGTHTC--QPGFLCQNTKGSFYCQARQRC 843


>gi|41281907 StAR-related lipid transfer (START) domain containing
           13 isoform beta [Homo sapiens]
          Length = 1105

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 21/96 (21%), Positives = 35/96 (36%), Gaps = 5/96 (5%)

Query: 63  CDICKDVVTAAGDMLKDNATEEEILVYLEKTCDWLPKPNMSASCKEIVDSYLPVILDIIK 122
           C  CKD V       + N T +   +  ++ CDWL         +   DS  P+ +  +K
Sbjct: 25  CRECKDTVCGGKQKSRVNHTFQRREIEAKEACDWLRAAGFPQYAQLYEDSQFPINIVAVK 84

Query: 123 G-----EMSRPGEVCSALNLCESLQKHLAELNHQKQ 153
                 E      +C  LN          ++N Q++
Sbjct: 85  NDHDFLEKDLVEPLCRRLNTLNKCASMKLDVNFQRK 120


>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 40/186 (21%), Positives = 74/186 (39%), Gaps = 24/186 (12%)

Query: 300 ELVEPIKKHEVPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLP------ 353
           +L++  KK ++P K     ++     K+V   +  + T KE+ D+  K  S+L       
Sbjct: 185 DLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRLK 244

Query: 354 ---KSLSE--ECQEVVDTYGSSILSILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKD 408
              K+L +  E +E++  Y      + + E    +  S L               T+P  
Sbjct: 245 WIHKALEQRKEYEEIMRDYIQKHPELNISEEG--ITKSTLTKAERQLKDKFDGRPTKPPP 302

Query: 409 GGFCEVCKKLVGYLD-----RNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEP 463
             +   C +L+  +        +   S + ++L+  EK      D Y K+CDQ   +YE 
Sbjct: 303 NSYSLYCAELMANMKDVPSTERMVLCSQQWKLLSQKEK------DAYHKKCDQKKKDYEV 356

Query: 464 VLIEIL 469
            L+  L
Sbjct: 357 ELLRFL 362


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 46/244 (18%), Positives = 103/244 (42%), Gaps = 18/244 (7%)

Query: 140 SLQKHLAELNHQKQLESNKIPELDMTEVVAPFMANIPLLLYPQDGPRSKPQPKDNG-DVC 198
           SL+  + ELN Q      K+ +LD+        A   LLL  +    ++     N  D  
Sbjct: 618 SLETSVNELNSQLNESKEKVSQLDI-----QIKAKTELLLSAEAAKTAQRADLQNHLDTA 672

Query: 199 QDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYISQYSE--IAIQMM 256
           Q+ +Q        + T    V A ++  +E C +L        ++++ +Y E  ++++  
Sbjct: 673 QNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQL--------ESHLKEYKEKYLSLEQK 724

Query: 257 MHMQDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNV-IPALELVEPIK-KHEVPAKS 314
               + Q K++ A        KE  +Q L   +  + ++ + A EL + ++ + E+ + +
Sbjct: 725 TEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSST 784

Query: 315 DVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSI 374
            +  +     ++ + + +   + EK+IL    +  S+  K   EE    + T  + +  +
Sbjct: 785 RLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKV 844

Query: 375 LLEE 378
            +E+
Sbjct: 845 KMEK 848


>gi|29788760 diacylglycerol kinase, eta isoform 1 [Homo sapiens]
          Length = 1164

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 35/151 (23%), Positives = 59/151 (39%), Gaps = 15/151 (9%)

Query: 310 VPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEV-VDTYG 368
           V + +   CE  +  V +V K  D       + DA    CS L + L +  Q +  D+  
Sbjct: 508 VISSAKTLCETVKDFVAKVEKTYDKTLENAVVADAVASKCSVLNEKLEQLLQALHTDSQA 567

Query: 369 SSIL----SILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDR 424
           + +L     +++EE   + V S      G     L   VT+P         +K V   + 
Sbjct: 568 APVLPGLSPLIVEE---DAVESSSEESLGESKEQLGDDVTKPSS-------QKAVKPREI 617

Query: 425 NLEKNSTKQEILAALEKGCSFLPDPYQKQCD 455
            L  NS K+ +   +E+    + DP    C+
Sbjct: 618 MLRANSLKKAVRQVIEEAGKVMDDPTVHPCE 648


>gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens]
          Length = 1220

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 35/151 (23%), Positives = 59/151 (39%), Gaps = 15/151 (9%)

Query: 310 VPAKSDVYCEVCEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEV-VDTYG 368
           V + +   CE  +  V +V K  D       + DA    CS L + L +  Q +  D+  
Sbjct: 508 VISSAKTLCETVKDFVAKVEKTYDKTLENAVVADAVASKCSVLNEKLEQLLQALHTDSQA 567

Query: 369 SSIL----SILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDR 424
           + +L     +++EE   + V S      G     L   VT+P         +K V   + 
Sbjct: 568 APVLPGLSPLIVEE---DAVESSSEESLGESKEQLGDDVTKPSS-------QKAVKPREI 617

Query: 425 NLEKNSTKQEILAALEKGCSFLPDPYQKQCD 455
            L  NS K+ +   +E+    + DP    C+
Sbjct: 618 MLRANSLKKAVRQVIEEAGKVMDDPTVHPCE 648


>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform
           b [Homo sapiens]
          Length = 1524

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 33/146 (22%), Positives = 66/146 (45%), Gaps = 10/146 (6%)

Query: 274 CDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAKSDVYCEVCEFLVKEV-TKLI 332
           CD++KE+P  T V  ++  +    AL ++E +  +      D+  E  + +  EV  + +
Sbjct: 404 CDDLKELPEPTPVKTRLPPEIFGDALMVLEFL--NAFGELFDLQDEFPDGVTLEVLEEAL 461

Query: 333 DNNKTEKEILDAFDKMCSKLPKSLSEECQEV-------VDTYGSSILSILLEEVSPELVC 385
             N +E  + +      + + ++++EE +EV        DT G S+ S+ L+  +   + 
Sbjct: 462 VGNDSEGPLCELLFFFLTAIFQAIAEEEEEVAKEQLTDADTKGCSLKSLDLDSCTLSEIL 521

Query: 386 SMLHLCSGTRLPALTVHVTQPKDGGF 411
            +  L SG  + +        K GGF
Sbjct: 522 RLHILASGADVTSANAKYRYQKRGGF 547


>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
            isoform 2 [Homo sapiens]
          Length = 2098

 Score = 30.8 bits (68), Expect = 3.2
 Identities = 19/61 (31%), Positives = 30/61 (49%)

Query: 418  LVGYLDRNLEKNSTKQEILAALEKGCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSF 477
            L+G  D  +++ ST + I A L  G S+ P P+    D+    YE   + I V   +PS 
Sbjct: 1610 LLGSTDSQVKEKSTMKAIFANLLPGNSYNPIPFPFDPDKHYLMYEHERVPIAVCEKEPSS 1669

Query: 478  V 478
            +
Sbjct: 1670 I 1670


>gi|24475849 hypothetical protein LOC203228 isoform b [Homo sapiens]
          Length = 222

 Score = 30.8 bits (68), Expect = 3.2
 Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 4/63 (6%)

Query: 254 QMMMHMQDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAK 313
           ++ MH + Q+  +   L G   E  E   Q+++P  + +  VIP +EL+  +K H VP +
Sbjct: 143 RIWMHKERQENVQKIILEG--TERMEDQGQSIIP--MLTGEVIPVMELLSSMKSHSVPEE 198

Query: 314 SDV 316
            D+
Sbjct: 199 IDI 201


>gi|37039612 hypothetical protein LOC203228 isoform a [Homo sapiens]
          Length = 481

 Score = 30.8 bits (68), Expect = 3.2
 Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 4/63 (6%)

Query: 254 QMMMHMQDQQPKEICALVGFCDEVKEMPMQTLVPAKVASKNVIPALELVEPIKKHEVPAK 313
           ++ MH + Q+  +   L G   E  E   Q+++P  + +  VIP +EL+  +K H VP +
Sbjct: 143 RIWMHKERQENVQKIILEG--TERMEDQGQSIIP--MLTGEVIPVMELLSSMKSHSVPEE 198

Query: 314 SDV 316
            D+
Sbjct: 199 IDI 201


>gi|39812027 amino-terminal enhancer of split isoform c [Homo
           sapiens]
          Length = 196

 Score = 30.8 bits (68), Expect = 3.2
 Identities = 29/131 (22%), Positives = 57/131 (43%), Gaps = 12/131 (9%)

Query: 189 PQPKDNGD--VCQDCIQMVTDIQTAVRTNSTFVQALVEHVKEECDRLGPGMADICKNYIS 246
           PQ + +G   + Q      +D    ++     +QA    +K ECD+L    +++ ++Y+ 
Sbjct: 4   PQSRHSGSSHLPQQLKFTTSDSCDRIKDEFQLLQAQYHSLKLECDKLASEKSEMQRHYVM 63

Query: 247 QYS-EIAIQMMMHMQDQQPKEICALVGFCDEV-----KEMPMQTLVPAKVASKNVIPAL- 299
            Y     + + MH Q +  K    L G C +V     +E   Q L   + A +   P L 
Sbjct: 64  YYEMSYGLNIEMHKQAEIVKR---LNGICAQVLPYLSQEHQQQVLGAIERAKQVTAPELN 120

Query: 300 ELVEPIKKHEV 310
            ++  ++ H++
Sbjct: 121 SIIRQLQAHQL 131


>gi|7706254 NOP58 ribonucleoprotein homolog [Homo sapiens]
          Length = 529

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 1/67 (1%)

Query: 327 EVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILL-EEVSPELVC 385
           E+ K+I +N T  + L       +     LSE   E V+    +   I +  EVS E +C
Sbjct: 193 ELGKIISDNLTYCKCLQKVGDRKNYASAKLSELLPEEVEAEVKAAAEISMGTEVSEEDIC 252

Query: 386 SMLHLCS 392
           ++LHLC+
Sbjct: 253 NILHLCT 259


>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
          Length = 1153

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 11/94 (11%)

Query: 383 LVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKG 442
           L+ + L LC G  L        Q    GF +   +L G    +       QEI+AA ++G
Sbjct: 6   LLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQG----SRVVVGAPQEIVAANQRG 61

Query: 443 CSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPS 476
             +       QCD      EP+ +++ VE ++ S
Sbjct: 62  SLY-------QCDYSTGSCEPIRLQVPVEAVNMS 88


>gi|7108344 granulysin isoform NKG5 [Homo sapiens]
          Length = 145

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 15/71 (21%), Positives = 35/71 (49%), Gaps = 1/71 (1%)

Query: 321 CEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVS 380
           C  +V+++ K++D   T++ + +A  ++C        + C+  +  Y S +   L+   +
Sbjct: 69  CLTIVQKLKKMVDK-PTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGET 127

Query: 381 PELVCSMLHLC 391
            + +C  L LC
Sbjct: 128 AQQICEDLRLC 138


>gi|157502222 granulysin isoform 519 [Homo sapiens]
          Length = 130

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 15/71 (21%), Positives = 35/71 (49%), Gaps = 1/71 (1%)

Query: 321 CEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVS 380
           C  +V+++ K++D   T++ + +A  ++C        + C+  +  Y S +   L+   +
Sbjct: 54  CLTIVQKLKKMVDK-PTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGET 112

Query: 381 PELVCSMLHLC 391
            + +C  L LC
Sbjct: 113 AQQICEDLRLC 123


>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
          Length = 1152

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 11/94 (11%)

Query: 383 LVCSMLHLCSGTRLPALTVHVTQPKDGGFCEVCKKLVGYLDRNLEKNSTKQEILAALEKG 442
           L+ + L LC G  L        Q    GF +   +L G    +       QEI+AA ++G
Sbjct: 6   LLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQG----SRVVVGAPQEIVAANQRG 61

Query: 443 CSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPS 476
             +       QCD      EP+ +++ VE ++ S
Sbjct: 62  SLY-------QCDYSTGSCEPIRLQVPVEAVNMS 88


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,690,922
Number of Sequences: 37866
Number of extensions: 1008213
Number of successful extensions: 2794
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 2697
Number of HSP's gapped (non-prelim): 76
length of query: 527
length of database: 18,247,518
effective HSP length: 107
effective length of query: 420
effective length of database: 14,195,856
effective search space: 5962259520
effective search space used: 5962259520
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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