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Search of human proteins with 15011924
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15011924 GTF2I repeat domain containing 1 isoform 2 [Homo
sapiens]
(944 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15011924 GTF2I repeat domain containing 1 isoform 2 [Homo sap... 1895 0.0
gi|7705387 GTF2I repeat domain containing 1 isoform 1 [Homo sapi... 1883 0.0
gi|169881252 general transcription factor II, i isoform 4 [Homo ... 379 e-105
gi|14670352 general transcription factor II, i isoform 2 [Homo s... 377 e-104
gi|14670354 general transcription factor II, i isoform 3 [Homo s... 375 e-104
gi|14670350 general transcription factor II, i isoform 1 [Homo s... 374 e-103
gi|239754606 PREDICTED: similar to hCG1983816 [Homo sapiens] 350 3e-96
gi|239749152 PREDICTED: similar to hCG1983816 [Homo sapiens] 350 5e-96
gi|239508897 PREDICTED: similar to hCG1983816 [Homo sapiens] 350 5e-96
gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens] 181 3e-45
gi|51241788 GTF2I repeat domain containing 2B [Homo sapiens] 181 3e-45
gi|239757552 PREDICTED: similar to hCG2006635, partial [Homo sap... 66 1e-10
gi|239746033 PREDICTED: hypothetical protein XP_002344174 [Homo ... 65 2e-10
gi|239752592 PREDICTED: hypothetical protein XP_002348308, parti... 64 9e-10
gi|78486540 DDB1 and CUL4 associated factor 15 [Homo sapiens] 38 0.039
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 37 0.067
gi|169213965 PREDICTED: similar to hCG1645909 [Homo sapiens] 35 0.43
gi|239751822 PREDICTED: similar to hCG1645909 [Homo sapiens] 35 0.43
gi|239746313 PREDICTED: similar to hCG1645909 [Homo sapiens] 35 0.43
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 35 0.43
gi|66472382 nischarin [Homo sapiens] 34 0.56
gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens] 34 0.56
gi|67010025 Sp4 transcription factor [Homo sapiens] 34 0.74
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor... 34 0.74
gi|27436957 membrane associated guanylate kinase, WW and PDZ dom... 33 0.96
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 33 0.96
gi|50409691 SRp25 nuclear protein isoform 4 [Homo sapiens] 33 0.96
gi|50409707 SRp25 nuclear protein isoform 2 [Homo sapiens] 33 0.96
gi|50409756 SRp25 nuclear protein isoform 1 [Homo sapiens] 33 0.96
gi|32699028 V-set and immunoglobulin domain containing 1 [Homo s... 33 0.96
>gi|15011924 GTF2I repeat domain containing 1 isoform 2 [Homo
sapiens]
Length = 944
Score = 1895 bits (4908), Expect = 0.0
Identities = 944/944 (100%), Positives = 944/944 (100%)
Query: 1 MALLGKRCDVPTNGCGPDRWNSAFTRKDEIITSLVSALDSMCSALSKLNAEVACVAVHDE 60
MALLGKRCDVPTNGCGPDRWNSAFTRKDEIITSLVSALDSMCSALSKLNAEVACVAVHDE
Sbjct: 1 MALLGKRCDVPTNGCGPDRWNSAFTRKDEIITSLVSALDSMCSALSKLNAEVACVAVHDE 60
Query: 61 SAFVVGTEKGRMFLNARKELQSDFLRFCRGPPWKDPEAEHPKKVQRGEGGGRSLPRSSLE 120
SAFVVGTEKGRMFLNARKELQSDFLRFCRGPPWKDPEAEHPKKVQRGEGGGRSLPRSSLE
Sbjct: 61 SAFVVGTEKGRMFLNARKELQSDFLRFCRGPPWKDPEAEHPKKVQRGEGGGRSLPRSSLE 120
Query: 121 HGSDVYLLRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAE 180
HGSDVYLLRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAE
Sbjct: 121 HGSDVYLLRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAE 180
Query: 181 YDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVP 240
YDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVP
Sbjct: 181 YDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVP 240
Query: 241 PQDLPPTATSSSMASFLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRPMPEPKATGAQD 300
PQDLPPTATSSSMASFLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRPMPEPKATGAQD
Sbjct: 241 PQDLPPTATSSSMASFLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRPMPEPKATGAQD 300
Query: 301 FSDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFN 360
FSDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFN
Sbjct: 301 FSDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFN 360
Query: 361 SRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIH 420
SRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIH
Sbjct: 361 SRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIH 420
Query: 421 FIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARSDKGSMSEDC 480
FIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARSDKGSMSEDC
Sbjct: 421 FIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARSDKGSMSEDC 480
Query: 481 GPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTD 540
GPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTD
Sbjct: 481 GPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTD 540
Query: 541 KGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEE 600
KGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEE
Sbjct: 541 KGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEE 600
Query: 601 LFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSG 660
LFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSG
Sbjct: 601 LFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSG 660
Query: 661 DPLVDESLKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIK 720
DPLVDESLKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIK
Sbjct: 661 DPLVDESLKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIK 720
Query: 721 SNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKPDEDDANR 780
SNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKPDEDDANR
Sbjct: 721 SNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKPDEDDANR 780
Query: 781 LGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTY 840
LGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTY
Sbjct: 781 LGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTY 840
Query: 841 DIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSS 900
DIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSS
Sbjct: 841 DIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSS 900
Query: 901 SSSSSSSSNPDSVASANQISLVQWPMYMVDYAGLNVQLPGPLNY 944
SSSSSSSSNPDSVASANQISLVQWPMYMVDYAGLNVQLPGPLNY
Sbjct: 901 SSSSSSSSNPDSVASANQISLVQWPMYMVDYAGLNVQLPGPLNY 944
>gi|7705387 GTF2I repeat domain containing 1 isoform 1 [Homo
sapiens]
Length = 959
Score = 1884 bits (4879), Expect = 0.0
Identities = 943/959 (98%), Positives = 944/959 (98%), Gaps = 15/959 (1%)
Query: 1 MALLGKRCDVPTNGCGPDRWNSAFTRKDEIITSLVSALDSMCSALSKLNAEVACVAVHDE 60
MALLGKRCDVPTNGCGPDRWNSAFTRKDEIITSLVSALDSMCSALSKLNAEVACVAVHDE
Sbjct: 1 MALLGKRCDVPTNGCGPDRWNSAFTRKDEIITSLVSALDSMCSALSKLNAEVACVAVHDE 60
Query: 61 SAFVVGTEKGRMFLNARKELQSDFLRFCRGPPWKDPEAEHPKKVQRGEGGGRSLPRSSLE 120
SAFVVGTEKGRMFLNARKELQSDFLRFCRGPPWKDPEAEHPKKVQRGEGGGRSLPRSSLE
Sbjct: 61 SAFVVGTEKGRMFLNARKELQSDFLRFCRGPPWKDPEAEHPKKVQRGEGGGRSLPRSSLE 120
Query: 121 HGSDVYLLRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAE 180
HGSDVYLLRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAE
Sbjct: 121 HGSDVYLLRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAE 180
Query: 181 YDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVP 240
YDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVP
Sbjct: 181 YDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVP 240
Query: 241 PQDLPPTATSSSMASFLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRPMPEPKATGAQD 300
PQDLPPTATSSSMASFLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRPMPEPKATGAQD
Sbjct: 241 PQDLPPTATSSSMASFLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRPMPEPKATGAQD 300
Query: 301 FSDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFN 360
FSDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFN
Sbjct: 301 FSDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFN 360
Query: 361 SRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIH 420
SRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIH
Sbjct: 361 SRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIH 420
Query: 421 FIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARSDKGSMSEDC 480
FIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARSDKGSMSEDC
Sbjct: 421 FIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARSDKGSMSEDC 480
Query: 481 GPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTD 540
GPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTD
Sbjct: 481 GPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTD 540
Query: 541 KGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEE 600
KGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEE
Sbjct: 541 KGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEE 600
Query: 601 LFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQ----- 655
LFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPI+DSQ
Sbjct: 601 LFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIMDSQGTASS 660
Query: 656 ----------ERDSGDPLVDESLKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEA 705
ERDSGDPLVDESLKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEA
Sbjct: 661 LGFSPPALPPERDSGDPLVDESLKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEA 720
Query: 706 LGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRP 765
LGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRP
Sbjct: 721 LGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRP 780
Query: 766 FQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEV 825
FQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEV
Sbjct: 781 FQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEV 840
Query: 826 TGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKR 885
TGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKR
Sbjct: 841 TGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKR 900
Query: 886 KRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQISLVQWPMYMVDYAGLNVQLPGPLNY 944
KRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQISLVQWPMYMVDYAGLNVQLPGPLNY
Sbjct: 901 KRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQISLVQWPMYMVDYAGLNVQLPGPLNY 959
>gi|169881252 general transcription factor II, i isoform 4 [Homo
sapiens]
Length = 957
Score = 379 bits (973), Expect = e-105
Identities = 299/970 (30%), Positives = 461/970 (47%), Gaps = 186/970 (19%)
Query: 30 IITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCR 89
++T L+SAL+SMC L+K AEVAC+AV++ FVVGTE+GR F+N RK+ Q DF+++C
Sbjct: 22 VVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCV 81
Query: 90 GPPWKDPEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASV 149
K E K + R S++ ++ LRK VE+ F Y +ALG+++V
Sbjct: 82 EEEEKAAEMHKMKSTTQAN-------RMSVD-AVEIETLRKTVEDYFCFCYGKALGKSTV 133
Query: 150 VPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLED--- 206
VP+PYE++LR+ + VQGLPEG+AF+ P YD L ILE+ I F +KRP +
Sbjct: 134 VPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFLEPKK 193
Query: 207 --GGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVPPQDLPPTATSSSMAS--------- 255
GGR + + + L P GS CG KV + + S MA+
Sbjct: 194 HVGGR--VMVTDADRSILSPGGS--CG----PIKVKTEPTEDSGISLEMAAVTVKEESED 245
Query: 256 ---FLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRPMPEPKATGAQDFSDCCGQKPTGP 312
+ Y+ +H+ E + D S P PKA P
Sbjct: 246 PDYYQYNIQGSHHSSE--GNEGTEMEVPAEDDDYSPPSKRPKANEL-------------P 290
Query: 313 GGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHM 372
P+ + +A KR + EKW+A I + LR+ V+ LF +YA+A+
Sbjct: 291 QPPVPEPANAGKR---KVREFNFEKWNARITD------LRKQVEELFERKYAQAIKAKGP 341
Query: 373 VPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIF 432
V +PY E + + G+P+ IPF+RP TYG+P+L+RIL + I F+IK+ E +
Sbjct: 342 VTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKK--HELL- 398
Query: 433 TGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARSDKGSMSEDCGPGTSGELGGLR 492
N +D +PAS ++ +R T L + K +E G T + +
Sbjct: 399 --NSTREDLQLDKPASGVKE--EWYARITKLRKMVDQLFCK-KFAEALG-STEAKAVPYQ 452
Query: 493 PIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGM----------------- 535
+ P DL + E + +++P P S YG+
Sbjct: 453 KFEAHPNDLYV------------EGLPENIPFRSP---SWYGIPRLEKIIQVGNRIKFVI 497
Query: 536 ---EMLTDKGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYS 592
E+LT PV++ I LRKQVE +FN ++A+A+G++E VKVPY
Sbjct: 498 KRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYP 557
Query: 593 KFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPEL--------LT 644
F +PE L+V GLPEGI R P FGI +L +I+ SN I+FV+K+PEL +
Sbjct: 558 VFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMA 617
Query: 645 EGVKEPIVDSQER------DSGDPLVDESL--------------------------KRQG 672
+ + S +R +S P ++ ++ K +G
Sbjct: 618 SKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRG 677
Query: 673 FQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLP 732
+ +++A ++I L+++V++LFN+K GEALG+K V+VP+ +S P +EGLP
Sbjct: 678 REFSFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLP 734
Query: 733 PGIPFRKPCTFGSQNLERILAVADKIKFTVTRP--------------------------- 765
G+PFR+P TFG LE+IL KIKF + +P
Sbjct: 735 EGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVN 794
Query: 766 -----------FQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYK 814
Q IP D + +++ + LREQV +LF+ K+GEA+G+ PV VPY+
Sbjct: 795 TTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYR 854
Query: 815 LIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPF-AEICNDA 873
I +P V V G+P + F+ P+ +I + +IL + E ++ +I +PF + N+
Sbjct: 855 KITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVI---RPFPGLVINNQ 911
Query: 874 KVPAKDSSIP 883
V +S P
Sbjct: 912 LVDQSESEGP 921
Score = 270 bits (691), Expect = 4e-72
Identities = 204/606 (33%), Positives = 291/606 (48%), Gaps = 92/606 (15%)
Query: 347 DINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGV 406
+I TLR+ V+ F Y +ALG +VPVPY K+ D AV + G+P+ + FK P Y +
Sbjct: 108 EIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDL 167
Query: 407 PKLKRILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLA 466
LK ILE + I FIIKR F LEP R V D
Sbjct: 168 ATLKWILENKAGISFIIKRPF----------------LEPKKHVG------GRVMVTDAD 205
Query: 467 GNARSDKGSMSEDCGP-----------GTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTS 515
+ S GS CGP G S E+ + +K E ED D Q + S S
Sbjct: 206 RSILSPGGS----CGPIKVKTEPTEDSGISLEMAAVT-VKEESEDPDYYQYNIQG-SHHS 259
Query: 516 EEMTDSMPGHLPSEDSGYGMEMLTDKG-------LSEDARPEERPVEDSHGDV----IRP 564
E + +P+ED Y K + E A +R V + + + I
Sbjct: 260 SEGNEGTEMEVPAEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD 319
Query: 565 LRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLR 624
LRKQVE LF +YA+AI PV +PY F H E+L+V GLPEGI RRP+ +GI +L
Sbjct: 320 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 379
Query: 625 KILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKRQGFQENYDARLSRI 684
+IL A I+FVIK+ ELL ++ +D G +E + AR+++
Sbjct: 380 RILLAKERIRFVIKKHELLNSTREDLQLDK--------------PASGVKEEWYARITK- 424
Query: 685 DIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFG 744
LR+ V LF KK+ EALG VPY++ +++P + +EGLP IPFR P +G
Sbjct: 425 -----LRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYG 479
Query: 745 SQNLERILAVADKIKFTVTRP----------FQGLIPKPDEDDANRLGEKVILREQVKEL 794
LE+I+ V ++IKF + RP Q P ++D N K LR+QV+E+
Sbjct: 480 IPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITK--LRKQVEEI 537
Query: 795 FNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREH 854
FN K+ +ALGL V VPY + +P+ + V GLP+ IPFR+P + I RLE+I++
Sbjct: 538 FNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNK 597
Query: 855 VRMV------IINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSS 908
++ V +I+ L P +K+ K PKR R S + +++
Sbjct: 598 IKFVVKKPELVISYLPPGMA----SKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNN 653
Query: 909 NPDSVA 914
NP + A
Sbjct: 654 NPQTSA 659
Score = 149 bits (375), Expect = 2e-35
Identities = 118/411 (28%), Positives = 193/411 (46%), Gaps = 105/411 (25%)
Query: 562 IRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIA 621
I LRK V+ LF ++A+A+G +E VPY KF HP +L+V GLPE I R P+ +GI
Sbjct: 422 ITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIP 481
Query: 622 KLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKRQGFQENYDARL 681
+L KI++ N I+FVIKRPELLT E V + +E+++ R+
Sbjct: 482 RLEKIIQVGNRIKFVIKRPELLTHSTTE--------------VTQPRTNTPVKEDWNVRI 527
Query: 682 SRIDIANTLREQVQDLFNKKYG------EALGIKY---------------PVQVPYK--- 717
++ LR+QV+++FN K+ EA+ + Y P +P++
Sbjct: 528 TK------LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPT 581
Query: 718 --------RIKSNPGSV---------IIEGLPPGIPFR----------KPCTFGSQNLER 750
RI + +I LPPG+ + +P + GS +
Sbjct: 582 WFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK-- 639
Query: 751 ILAVADKIKFTV-----TRPFQGLIPKPDEDDANRLGEK---------------VILREQ 790
+I+ TV P + P + + + + K L+++
Sbjct: 640 ----VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQK 695
Query: 791 VKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILK 850
V+ LFNEK GEALGL + V VP+ L P+ V GLP+ +PFR P+T+ I RLEKIL+
Sbjct: 696 VENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILR 755
Query: 851 AREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSS 901
+ ++ II + + F + K+S+ K ++++ +V++++S
Sbjct: 756 NKAKIKF-IIKKPEMF-------ETAIKESTSSKSPPRKINSSPNVNTTAS 798
Score = 102 bits (255), Expect = 1e-21
Identities = 109/410 (26%), Positives = 172/410 (41%), Gaps = 80/410 (19%)
Query: 128 LRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALM 187
LRK VEE+F++ +++ALG V +PY P L V+GLPEG+ FR P + L
Sbjct: 530 LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLE 589
Query: 188 AILEHSHRIRFKLKRP-LEDGGRDSKALVELNGVSL-IPKGSRDCGLHGQAPKV------ 239
I+ S++I+F +K+P L ++N +L PK R G + + P++
Sbjct: 590 RIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEG 649
Query: 240 PPQDLP-------PTATSSSMASFL-----YSTALPNHAIRELKQEAPSC--PLAPSDLG 285
P + P PT T+ S F +S N I +LKQ+ + LG
Sbjct: 650 PNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALG 709
Query: 286 LSRPMPEPKA---TGAQDF------SDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSE 336
L + + P A + +DF ++P+ G P ++ + +K + I+ K E
Sbjct: 710 LKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIK-KPE 768
Query: 337 KWDAFIKET-----------------------EDINT---------------------LR 352
++ IKE+ ED+N LR
Sbjct: 769 MFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLR 828
Query: 353 ECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRI 412
E V LF+ ++ EA+G+ V VPYRKI +P V + G+P + FK P + ++RI
Sbjct: 829 EQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRI 888
Query: 413 LEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATV 462
L+ I F + R F + + E P SAE S+ V
Sbjct: 889 LDSAEFIKFTVIRPFPGLVINNQLVDQS----ESEGPVIQESAEPSQLEV 934
>gi|14670352 general transcription factor II, i isoform 2 [Homo
sapiens]
Length = 978
Score = 377 bits (968), Expect = e-104
Identities = 302/979 (30%), Positives = 469/979 (47%), Gaps = 183/979 (18%)
Query: 30 IITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCR 89
++T L+SAL+SMC L+K AEVAC+AV++ FVVGTE+GR F+N RK+ Q DF+++C
Sbjct: 22 VVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCV 81
Query: 90 GPPWKDPEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASV 149
K E K + R S++ ++ LRK VE+ F Y +ALG+++V
Sbjct: 82 EEEEKAAEMHKMKSTTQAN-------RMSVD-AVEIETLRKTVEDYFCFCYGKALGKSTV 133
Query: 150 VPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLED--- 206
VP+PYE++LR+ + VQGLPEG+AF+ P YD L ILE+ I F +KRP +
Sbjct: 134 VPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFLEPKK 193
Query: 207 --GGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVPPQDLPPTATSSSMAS--------- 255
GGR + + + L P GS CG KV + + S MA+
Sbjct: 194 HVGGR--VMVTDADRSILSPGGS--CG----PIKVKTEPTEDSGISLEMAAVTVKEESED 245
Query: 256 ---FLYSTALPNHAI---RELKQEAP---SCPLAPSDLGLSRPMPEPKATGAQDFSDCCG 306
+ Y+ +H+ + E P S PS+ + PE + T D
Sbjct: 246 PDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSE---TSEDPEVEVTIEDDDYSPPS 302
Query: 307 QKPTG---PGGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFNSRY 363
++P P P+ + +A KR + EKW+A I + LR+ V+ LF +Y
Sbjct: 303 KRPKANELPQPPVPEPANAGKR---KVREFNFEKWNARITD------LRKQVEELFERKY 353
Query: 364 AEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFII 423
A+A+ V +PY E + + G+P+ IPF+RP TYG+P+L+RIL + I F+I
Sbjct: 354 AQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVI 413
Query: 424 KRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARSDKGSMSEDCGPG 483
K+ E + N +D +PAS ++ +R T L + K +E G
Sbjct: 414 KK--HELL---NSTREDLQLDKPASGVKE--EWYARITKLRKMVDQLFCK-KFAEALG-S 464
Query: 484 TSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGM-------- 535
T + + + P DL + E + +++P P S YG+
Sbjct: 465 TEAKAVPYQKFEAHPNDLYV------------EGLPENIPFRSP---SWYGIPRLEKIIQ 509
Query: 536 ------------EMLTDKGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGI 583
E+LT PV++ I LRKQVE +FN ++A+A+G+
Sbjct: 510 VGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGL 569
Query: 584 SEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPEL- 642
+E VKVPY F +PE L+V GLPEGI R P FGI +L +I+ SN I+FV+K+PEL
Sbjct: 570 TEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELV 629
Query: 643 -------LTEGVKEPIVDSQER------DSGDPLVDESL--------------------- 668
+ + + S +R +S P ++ ++
Sbjct: 630 ISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNG 689
Query: 669 -----KRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNP 723
K +G + +++A ++I L+++V++LFN+K GEALG+K V+VP+ +S P
Sbjct: 690 SNVPFKPRGREFSFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFP 746
Query: 724 GSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRP------------------ 765
+EGLP G+PFR+P TFG LE+IL KIKF + +P
Sbjct: 747 EDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPR 806
Query: 766 --------------------FQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGL 805
Q IP D + +++ + LREQV +LF+ K+GEA+G+
Sbjct: 807 KINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGM 866
Query: 806 NRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQP 865
PV VPY+ I +P V V G+P + F+ P+ +I + +IL + E ++ +I +P
Sbjct: 867 GFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVI---RP 923
Query: 866 F-AEICNDAKVPAKDSSIP 883
F + N+ V +S P
Sbjct: 924 FPGLVINNQLVDQSESEGP 942
Score = 263 bits (672), Expect = 6e-70
Identities = 198/605 (32%), Positives = 289/605 (47%), Gaps = 69/605 (11%)
Query: 347 DINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGV 406
+I TLR+ V+ F Y +ALG +VPVPY K+ D AV + G+P+ + FK P Y +
Sbjct: 108 EIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDL 167
Query: 407 PKLKRILEERHSIHFIIKRMFDE--RIFTGNKFTKDTTK--LEPAS----------PPED 452
LK ILE + I FIIKR F E + G D + L P P ED
Sbjct: 168 ATLKWILENKAGISFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTED 227
Query: 453 TSAEVSRATVLDLAGNARSDKGSMS-EDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDP 511
+ + A V + D + + + G G + E + T DP
Sbjct: 228 SGISLEMAAVTVKEESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDP 287
Query: 512 SP--TSEEMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPVEDSHGDV----IRPL 565
T E+ S P P + L + E A +R V + + + I L
Sbjct: 288 EVEVTIEDDDYSPPSKRPKANE------LPQPPVPEPANAGKRKVREFNFEKWNARITDL 341
Query: 566 RKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRK 625
RKQVE LF +YA+AI PV +PY F H E+L+V GLPEGI RRP+ +GI +L +
Sbjct: 342 RKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLER 401
Query: 626 ILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKRQGFQENYDARLSRID 685
IL A I+FVIK+ ELL ++ +D G +E + AR+++
Sbjct: 402 ILLAKERIRFVIKKHELLNSTREDLQLDK--------------PASGVKEEWYARITK-- 445
Query: 686 IANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGS 745
LR+ V LF KK+ EALG VPY++ +++P + +EGLP IPFR P +G
Sbjct: 446 ----LRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGI 501
Query: 746 QNLERILAVADKIKFTVTRP----------FQGLIPKPDEDDANRLGEKVILREQVKELF 795
LE+I+ V ++IKF + RP Q P ++D N K LR+QV+E+F
Sbjct: 502 PRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITK--LRKQVEEIF 559
Query: 796 NEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHV 855
N K+ +ALGL V VPY + +P+ + V GLP+ IPFR+P + I RLE+I++ +
Sbjct: 560 NLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKI 619
Query: 856 RMV------IINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSN 909
+ V +I+ L P +K+ K PKR R S + +++N
Sbjct: 620 KFVVKKPELVISYLPPGMA----SKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNN 675
Query: 910 PDSVA 914
P + A
Sbjct: 676 PQTSA 680
Score = 149 bits (375), Expect = 2e-35
Identities = 118/411 (28%), Positives = 193/411 (46%), Gaps = 105/411 (25%)
Query: 562 IRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIA 621
I LRK V+ LF ++A+A+G +E VPY KF HP +L+V GLPE I R P+ +GI
Sbjct: 443 ITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIP 502
Query: 622 KLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKRQGFQENYDARL 681
+L KI++ N I+FVIKRPELLT E V + +E+++ R+
Sbjct: 503 RLEKIIQVGNRIKFVIKRPELLTHSTTE--------------VTQPRTNTPVKEDWNVRI 548
Query: 682 SRIDIANTLREQVQDLFNKKYG------EALGIKY---------------PVQVPYK--- 717
++ LR+QV+++FN K+ EA+ + Y P +P++
Sbjct: 549 TK------LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPT 602
Query: 718 --------RIKSNPGSV---------IIEGLPPGIPFR----------KPCTFGSQNLER 750
RI + +I LPPG+ + +P + GS +
Sbjct: 603 WFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK-- 660
Query: 751 ILAVADKIKFTV-----TRPFQGLIPKPDEDDANRLGEK---------------VILREQ 790
+I+ TV P + P + + + + K L+++
Sbjct: 661 ----VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQK 716
Query: 791 VKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILK 850
V+ LFNEK GEALGL + V VP+ L P+ V GLP+ +PFR P+T+ I RLEKIL+
Sbjct: 717 VENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILR 776
Query: 851 AREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSS 901
+ ++ II + + F + K+S+ K ++++ +V++++S
Sbjct: 777 NKAKIKF-IIKKPEMF-------ETAIKESTSSKSPPRKINSSPNVNTTAS 819
Score = 102 bits (255), Expect = 1e-21
Identities = 109/410 (26%), Positives = 172/410 (41%), Gaps = 80/410 (19%)
Query: 128 LRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALM 187
LRK VEE+F++ +++ALG V +PY P L V+GLPEG+ FR P + L
Sbjct: 551 LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLE 610
Query: 188 AILEHSHRIRFKLKRP-LEDGGRDSKALVELNGVSL-IPKGSRDCGLHGQAPKV------ 239
I+ S++I+F +K+P L ++N +L PK R G + + P++
Sbjct: 611 RIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEG 670
Query: 240 PPQDLP-------PTATSSSMASFL-----YSTALPNHAIRELKQEAPSC--PLAPSDLG 285
P + P PT T+ S F +S N I +LKQ+ + LG
Sbjct: 671 PNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALG 730
Query: 286 LSRPMPEPKA---TGAQDF------SDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSE 336
L + + P A + +DF ++P+ G P ++ + +K + I+ K E
Sbjct: 731 LKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIK-KPE 789
Query: 337 KWDAFIKET-----------------------EDINT---------------------LR 352
++ IKE+ ED+N LR
Sbjct: 790 MFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLR 849
Query: 353 ECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRI 412
E V LF+ ++ EA+G+ V VPYRKI +P V + G+P + FK P + ++RI
Sbjct: 850 EQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRI 909
Query: 413 LEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATV 462
L+ I F + R F + + E P SAE S+ V
Sbjct: 910 LDSAEFIKFTVIRPFPGLVINNQLVDQS----ESEGPVIQESAEPSQLEV 955
>gi|14670354 general transcription factor II, i isoform 3 [Homo
sapiens]
Length = 977
Score = 375 bits (964), Expect = e-104
Identities = 297/977 (30%), Positives = 464/977 (47%), Gaps = 180/977 (18%)
Query: 30 IITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCR 89
++T L+SAL+SMC L+K AEVAC+AV++ FVVGTE+GR F+N RK+ Q DF+++C
Sbjct: 22 VVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCV 81
Query: 90 GPPWKDPEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASV 149
K E K + R S++ ++ LRK VE+ F Y +ALG+++V
Sbjct: 82 EEEEKAAEMHKMKSTTQAN-------RMSVD-AVEIETLRKTVEDYFCFCYGKALGKSTV 133
Query: 150 VPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLED--- 206
VP+PYE++LR+ + VQGLPEG+AF+ P YD L ILE+ I F +KRP +
Sbjct: 134 VPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFLEPKK 193
Query: 207 --GGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVPPQDLPPTATSSSMASFLYSTALPN 264
GGR + + + L P GS CG KV + + S MA+ +
Sbjct: 194 HVGGR--VMVTDADRSILSPGGS--CG----PIKVKTEPTEDSGISLEMAAVTVKEESED 245
Query: 265 HAIRELKQEAPSCPLAPSDLGLSRPMPEP----------------KATGAQDFSDCCGQK 308
+ +A P D+ +P+ +P + D ++
Sbjct: 246 PDYYQYNIQAG--PSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDDDYSPPSKR 303
Query: 309 PTG---PGGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFNSRYAE 365
P P P+ + +A KR + EKW+A I + LR+ V+ LF +YA+
Sbjct: 304 PKANELPQPPVPEPANAGKR---KVREFNFEKWNARITD------LRKQVEELFERKYAQ 354
Query: 366 ALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKR 425
A+ V +PY E + + G+P+ IPF+RP TYG+P+L+RIL + I F+IK+
Sbjct: 355 AIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKK 414
Query: 426 MFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARSDKGSMSEDCGPGTS 485
E + N +D +PAS ++ +R T L + K +E G T
Sbjct: 415 --HELL---NSTREDLQLDKPASGVKE--EWYARITKLRKMVDQLFCK-KFAEALG-STE 465
Query: 486 GELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGM---------- 535
+ + + P DL + E + +++P P S YG+
Sbjct: 466 AKAVPYQKFEAHPNDLYV------------EGLPENIPFRSP---SWYGIPRLEKIIQVG 510
Query: 536 ----------EMLTDKGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGISE 585
E+LT PV++ I LRKQVE +FN ++A+A+G++E
Sbjct: 511 NRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTE 570
Query: 586 PVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPEL--- 642
VKVPY F +PE L+V GLPEGI R P FGI +L +I+ SN I+FV+K+PEL
Sbjct: 571 AVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVIS 630
Query: 643 -----LTEGVKEPIVDSQER------DSGDPLVDESL----------------------- 668
+ + + S +R +S P ++ ++
Sbjct: 631 YLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSN 690
Query: 669 ---KRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGS 725
K +G + +++A ++I L+++V++LFN+K GEALG+K V+VP+ +S P
Sbjct: 691 VPFKPRGREFSFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPED 747
Query: 726 VIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRP-------------------- 765
+EGLP G+PFR+P TFG LE+IL KIKF + +P
Sbjct: 748 FYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKI 807
Query: 766 ------------------FQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNR 807
Q IP D + +++ + LREQV +LF+ K+GEA+G+
Sbjct: 808 NSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGF 867
Query: 808 PVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPF- 866
PV VPY+ I +P V V G+P + F+ P+ +I + +IL + E ++ +I +PF
Sbjct: 868 PVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVI---RPFP 924
Query: 867 AEICNDAKVPAKDSSIP 883
+ N+ V +S P
Sbjct: 925 GLVINNQLVDQSESEGP 941
Score = 268 bits (684), Expect = 2e-71
Identities = 197/609 (32%), Positives = 291/609 (47%), Gaps = 78/609 (12%)
Query: 347 DINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGV 406
+I TLR+ V+ F Y +ALG +VPVPY K+ D AV + G+P+ + FK P Y +
Sbjct: 108 EIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDL 167
Query: 407 PKLKRILEERHSIHFIIKRMFDE--RIFTGNKFTKDTTK--LEPAS----------PPED 452
LK ILE + I FIIKR F E + G D + L P P ED
Sbjct: 168 ATLKWILENKAGISFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTED 227
Query: 453 TSAEVSRATVLDLAGNARSDKGSMSEDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPS 512
+ + A V + D + GP + ++ +P+ + S
Sbjct: 228 SGISLEMAAVTVKEESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQG-----------S 276
Query: 513 PTSEEMTDSMPGHLPSEDSGYGMEMLTDKG-------LSEDARPEERPVEDSHGDV---- 561
S E + +P+ED Y K + E A +R V + + +
Sbjct: 277 HHSSEGNEGTEMEVPAEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNAR 336
Query: 562 IRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIA 621
I LRKQVE LF +YA+AI PV +PY F H E+L+V GLPEGI RRP+ +GI
Sbjct: 337 ITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIP 396
Query: 622 KLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKRQGFQENYDARL 681
+L +IL A I+FVIK+ ELL ++ +D G +E + AR+
Sbjct: 397 RLERILLAKERIRFVIKKHELLNSTREDLQLDK--------------PASGVKEEWYARI 442
Query: 682 SRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPC 741
++ LR+ V LF KK+ EALG VPY++ +++P + +EGLP IPFR P
Sbjct: 443 TK------LRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPS 496
Query: 742 TFGSQNLERILAVADKIKFTVTRP----------FQGLIPKPDEDDANRLGEKVILREQV 791
+G LE+I+ V ++IKF + RP Q P ++D N K LR+QV
Sbjct: 497 WYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITK--LRKQV 554
Query: 792 KELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKA 851
+E+FN K+ +ALGL V VPY + +P+ + V GLP+ IPFR+P + I RLE+I++
Sbjct: 555 EEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRG 614
Query: 852 REHVRMV------IINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSS 905
++ V +I+ L P +K+ K PKR R S +
Sbjct: 615 SNKIKFVVKKPELVISYLPPGMA----SKINTKALQSPKRPRSPGSNSKVPEIEVTVEGP 670
Query: 906 SSSNPDSVA 914
+++NP + A
Sbjct: 671 NNNNPQTSA 679
Score = 149 bits (375), Expect = 2e-35
Identities = 118/411 (28%), Positives = 193/411 (46%), Gaps = 105/411 (25%)
Query: 562 IRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIA 621
I LRK V+ LF ++A+A+G +E VPY KF HP +L+V GLPE I R P+ +GI
Sbjct: 442 ITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIP 501
Query: 622 KLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKRQGFQENYDARL 681
+L KI++ N I+FVIKRPELLT E V + +E+++ R+
Sbjct: 502 RLEKIIQVGNRIKFVIKRPELLTHSTTE--------------VTQPRTNTPVKEDWNVRI 547
Query: 682 SRIDIANTLREQVQDLFNKKYG------EALGIKY---------------PVQVPYK--- 717
++ LR+QV+++FN K+ EA+ + Y P +P++
Sbjct: 548 TK------LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPT 601
Query: 718 --------RIKSNPGSV---------IIEGLPPGIPFR----------KPCTFGSQNLER 750
RI + +I LPPG+ + +P + GS +
Sbjct: 602 WFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK-- 659
Query: 751 ILAVADKIKFTV-----TRPFQGLIPKPDEDDANRLGEK---------------VILREQ 790
+I+ TV P + P + + + + K L+++
Sbjct: 660 ----VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQK 715
Query: 791 VKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILK 850
V+ LFNEK GEALGL + V VP+ L P+ V GLP+ +PFR P+T+ I RLEKIL+
Sbjct: 716 VENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILR 775
Query: 851 AREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSS 901
+ ++ II + + F + K+S+ K ++++ +V++++S
Sbjct: 776 NKAKIKF-IIKKPEMF-------ETAIKESTSSKSPPRKINSSPNVNTTAS 818
Score = 102 bits (255), Expect = 1e-21
Identities = 109/410 (26%), Positives = 172/410 (41%), Gaps = 80/410 (19%)
Query: 128 LRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALM 187
LRK VEE+F++ +++ALG V +PY P L V+GLPEG+ FR P + L
Sbjct: 550 LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLE 609
Query: 188 AILEHSHRIRFKLKRP-LEDGGRDSKALVELNGVSL-IPKGSRDCGLHGQAPKV------ 239
I+ S++I+F +K+P L ++N +L PK R G + + P++
Sbjct: 610 RIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEG 669
Query: 240 PPQDLP-------PTATSSSMASFL-----YSTALPNHAIRELKQEAPSC--PLAPSDLG 285
P + P PT T+ S F +S N I +LKQ+ + LG
Sbjct: 670 PNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALG 729
Query: 286 LSRPMPEPKA---TGAQDF------SDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSE 336
L + + P A + +DF ++P+ G P ++ + +K + I+ K E
Sbjct: 730 LKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIK-KPE 788
Query: 337 KWDAFIKET-----------------------EDINT---------------------LR 352
++ IKE+ ED+N LR
Sbjct: 789 MFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLR 848
Query: 353 ECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRI 412
E V LF+ ++ EA+G+ V VPYRKI +P V + G+P + FK P + ++RI
Sbjct: 849 EQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRI 908
Query: 413 LEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATV 462
L+ I F + R F + + E P SAE S+ V
Sbjct: 909 LDSAEFIKFTVIRPFPGLVINNQLVDQS----ESEGPVIQESAEPSQLEV 954
>gi|14670350 general transcription factor II, i isoform 1 [Homo
sapiens]
Length = 998
Score = 374 bits (960), Expect = e-103
Identities = 299/991 (30%), Positives = 467/991 (47%), Gaps = 187/991 (18%)
Query: 30 IITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCR 89
++T L+SAL+SMC L+K AEVAC+AV++ FVVGTE+GR F+N RK+ Q DF+++C
Sbjct: 22 VVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCV 81
Query: 90 GPPWKDPEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASV 149
K E K + R S++ ++ LRK VE+ F Y +ALG+++V
Sbjct: 82 EEEEKAAEMHKMKSTTQAN-------RMSVD-AVEIETLRKTVEDYFCFCYGKALGKSTV 133
Query: 150 VPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLED--- 206
VP+PYE++LR+ + VQGLPEG+AF+ P YD L ILE+ I F +KRP +
Sbjct: 134 VPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFLEPKK 193
Query: 207 --GGR------DSKAL---------------VELNGVSL------IPKGSRDCGLHGQAP 237
GGR D L E +G+SL + + S D +
Sbjct: 194 HVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNI 253
Query: 238 KVPPQDLPPTATSSSMASFLYSTALPNHAIRELKQEAP---SCPLAPSDLGLSRPMPEPK 294
+ P + ++ L + + + E P S PS+ + PE +
Sbjct: 254 QAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVPSE---TSEDPEVE 310
Query: 295 ATGAQDFSDCCGQKPTG---PGGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTL 351
T D ++P P P+ + +A KR + EKW+A I + L
Sbjct: 311 VTIEDDDYSPPSKRPKANELPQPPVPEPANAGKR---KVREFNFEKWNARITD------L 361
Query: 352 RECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKR 411
R+ V+ LF +YA+A+ V +PY E + + G+P+ IPF+RP TYG+P+L+R
Sbjct: 362 RKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLER 421
Query: 412 ILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARS 471
IL + I F+IK+ E + N +D +PAS ++ +R T L +
Sbjct: 422 ILLAKERIRFVIKK--HELL---NSTREDLQLDKPASGVKE--EWYARITKLRKMVDQLF 474
Query: 472 DKGSMSEDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDS 531
K +E G T + + + P DL + E + +++P P S
Sbjct: 475 CK-KFAEALG-STEAKAVPYQKFEAHPNDLYV------------EGLPENIPFRSP---S 517
Query: 532 GYGM--------------------EMLTDKGLSEDARPEERPVEDSHGDVIRPLRKQVEL 571
YG+ E+LT PV++ I LRKQVE
Sbjct: 518 WYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEE 577
Query: 572 LFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASN 631
+FN ++A+A+G++E VKVPY F +PE L+V GLPEGI R P FGI +L +I+ SN
Sbjct: 578 IFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSN 637
Query: 632 SIQFVIKRPEL--------LTEGVKEPIVDSQER------DSGDPLVDESL--------- 668
I+FV+K+PEL + + + S +R +S P ++ ++
Sbjct: 638 KIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQ 697
Query: 669 -----------------KRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYP 711
K +G + +++A ++I L+++V++LFN+K GEALG+K
Sbjct: 698 TSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQA 754
Query: 712 VQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRP------ 765
V+VP+ +S P +EGLP G+PFR+P TFG LE+IL KIKF + +P
Sbjct: 755 VKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETA 814
Query: 766 --------------------------------FQGLIPKPDEDDANRLGEKVILREQVKE 793
Q IP D + +++ + LREQV +
Sbjct: 815 IKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVND 874
Query: 794 LFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKARE 853
LF+ K+GEA+G+ PV VPY+ I +P V V G+P + F+ P+ +I + +IL + E
Sbjct: 875 LFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAE 934
Query: 854 HVRMVIINQLQPF-AEICNDAKVPAKDSSIP 883
++ +I +PF + N+ V +S P
Sbjct: 935 FIKFTVI---RPFPGLVINNQLVDQSESEGP 962
Score = 265 bits (677), Expect = 2e-70
Identities = 202/620 (32%), Positives = 297/620 (47%), Gaps = 79/620 (12%)
Query: 347 DINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGV 406
+I TLR+ V+ F Y +ALG +VPVPY K+ D AV + G+P+ + FK P Y +
Sbjct: 108 EIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDL 167
Query: 407 PKLKRILEERHSIHFIIKRMFDE--RIFTGNKFTKDTTK--LEPAS----------PPED 452
LK ILE + I FIIKR F E + G D + L P P ED
Sbjct: 168 ATLKWILENKAGISFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTED 227
Query: 453 TSAEVSRATVLDLAGNARSDKGSMSEDCGPGTSGELGGLRPIK---------IEPEDLDI 503
+ + A V + D + GP + ++ +P+ E +
Sbjct: 228 SGISLEMAAVTVKEESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTE 287
Query: 504 IQVTVPD-----PSPTSE----EMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPV 554
++V D PS TSE E+T + P E L + E A +R V
Sbjct: 288 MEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSPPSKRPKANE-LPQPPVPEPANAGKRKV 346
Query: 555 EDSHGDV----IRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGI 610
+ + + I LRKQVE LF +YA+AI PV +PY F H E+L+V GLPEGI
Sbjct: 347 REFNFEKWNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGI 406
Query: 611 SLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKR 670
RRP+ +GI +L +IL A I+FVIK+ ELL ++ +D
Sbjct: 407 PFRRPSTYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDK--------------PA 452
Query: 671 QGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEG 730
G +E + AR+++ LR+ V LF KK+ EALG VPY++ +++P + +EG
Sbjct: 453 SGVKEEWYARITK------LRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEG 506
Query: 731 LPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRP----------FQGLIPKPDEDDANR 780
LP IPFR P +G LE+I+ V ++IKF + RP Q P ++D N
Sbjct: 507 LPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNV 566
Query: 781 LGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTY 840
K LR+QV+E+FN K+ +ALGL V VPY + +P+ + V GLP+ IPFR+P +
Sbjct: 567 RITK--LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWF 624
Query: 841 DIHRLEKILKAREHVRMV------IINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGN 894
I RLE+I++ ++ V +I+ L P +K+ K PKR R S
Sbjct: 625 GIPRLERIVRGSNKIKFVVKKPELVISYLPPGMA----SKINTKALQSPKRPRSPGSNSK 680
Query: 895 SVSSSSSSSSSSSSNPDSVA 914
+ +++NP + A
Sbjct: 681 VPEIEVTVEGPNNNNPQTSA 700
Score = 149 bits (375), Expect = 2e-35
Identities = 118/411 (28%), Positives = 193/411 (46%), Gaps = 105/411 (25%)
Query: 562 IRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIA 621
I LRK V+ LF ++A+A+G +E VPY KF HP +L+V GLPE I R P+ +GI
Sbjct: 463 ITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIP 522
Query: 622 KLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKRQGFQENYDARL 681
+L KI++ N I+FVIKRPELLT E V + +E+++ R+
Sbjct: 523 RLEKIIQVGNRIKFVIKRPELLTHSTTE--------------VTQPRTNTPVKEDWNVRI 568
Query: 682 SRIDIANTLREQVQDLFNKKYG------EALGIKY---------------PVQVPYK--- 717
++ LR+QV+++FN K+ EA+ + Y P +P++
Sbjct: 569 TK------LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPT 622
Query: 718 --------RIKSNPGSV---------IIEGLPPGIPFR----------KPCTFGSQNLER 750
RI + +I LPPG+ + +P + GS +
Sbjct: 623 WFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK-- 680
Query: 751 ILAVADKIKFTV-----TRPFQGLIPKPDEDDANRLGEK---------------VILREQ 790
+I+ TV P + P + + + + K L+++
Sbjct: 681 ----VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQK 736
Query: 791 VKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILK 850
V+ LFNEK GEALGL + V VP+ L P+ V GLP+ +PFR P+T+ I RLEKIL+
Sbjct: 737 VENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILR 796
Query: 851 AREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSS 901
+ ++ II + + F + K+S+ K ++++ +V++++S
Sbjct: 797 NKAKIKF-IIKKPEMF-------ETAIKESTSSKSPPRKINSSPNVNTTAS 839
Score = 102 bits (255), Expect = 1e-21
Identities = 109/410 (26%), Positives = 172/410 (41%), Gaps = 80/410 (19%)
Query: 128 LRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALM 187
LRK VEE+F++ +++ALG V +PY P L V+GLPEG+ FR P + L
Sbjct: 571 LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLE 630
Query: 188 AILEHSHRIRFKLKRP-LEDGGRDSKALVELNGVSL-IPKGSRDCGLHGQAPKV------ 239
I+ S++I+F +K+P L ++N +L PK R G + + P++
Sbjct: 631 RIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEG 690
Query: 240 PPQDLP-------PTATSSSMASFL-----YSTALPNHAIRELKQEAPSC--PLAPSDLG 285
P + P PT T+ S F +S N I +LKQ+ + LG
Sbjct: 691 PNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALG 750
Query: 286 LSRPMPEPKA---TGAQDF------SDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSE 336
L + + P A + +DF ++P+ G P ++ + +K + I+ K E
Sbjct: 751 LKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIK-KPE 809
Query: 337 KWDAFIKET-----------------------EDINT---------------------LR 352
++ IKE+ ED+N LR
Sbjct: 810 MFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLR 869
Query: 353 ECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRI 412
E V LF+ ++ EA+G+ V VPYRKI +P V + G+P + FK P + ++RI
Sbjct: 870 EQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRI 929
Query: 413 LEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATV 462
L+ I F + R F + + E P SAE S+ V
Sbjct: 930 LDSAEFIKFTVIRPFPGLVINNQLVDQS----ESEGPVIQESAEPSQLEV 975
>gi|239754606 PREDICTED: similar to hCG1983816 [Homo sapiens]
Length = 298
Score = 350 bits (899), Expect = 3e-96
Identities = 201/301 (66%), Positives = 216/301 (71%), Gaps = 65/301 (21%)
Query: 596 MHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQ 655
MHPEELFVVGLPEGISLRRPNCFGIAKL KILEASNSIQFVIKRP+LLTEGVKEPIVDSQ
Sbjct: 1 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ 60
Query: 656 ---------------ERDSGDPLVDESLKRQGFQENYDARLSRIDIANTLREQVQDLFNK 700
ERDS DPLV ESLKRQGFQENYDARL RIDIANTLREQVQ+LFNK
Sbjct: 61 GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK 120
Query: 701 KYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKF 760
YGEALGIKYPVQVPYK IKSNPGS+IIE LPPGI FRKP FGSQNLERILA+A+KI F
Sbjct: 121 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITF 178
Query: 761 TVTRPFQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSP 820
TVTRPFQGLI KPDEDD NRLGE VIL+EQVKELFNEKY + L L
Sbjct: 179 TVTRPFQGLIRKPDEDDTNRLGE-VILQEQVKELFNEKYSQCLWL--------------- 222
Query: 821 DAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVPAKDS 880
L+ ++H I++ +PFAEICNDAKVP +
Sbjct: 223 ----------------------------LQQQQH----HISEGRPFAEICNDAKVPGESE 250
Query: 881 S 881
+
Sbjct: 251 A 251
Score = 75.1 bits (183), Expect = 3e-13
Identities = 58/203 (28%), Positives = 88/203 (43%), Gaps = 34/203 (16%)
Query: 504 IQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPVEDSHGDVIR 563
++ + D T+ + S P P DS + L + L E D+
Sbjct: 52 VKEPIVDSQGTASSLGFSPPALPPERDS---RDPLVGESLKRQGFQENYDARLLRIDIAN 108
Query: 564 PLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKL 623
LR+QV+ LFN Y +A+GI PV+VPY +P + + LP GI R+P FG L
Sbjct: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166
Query: 624 RKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKRQGFQENYDARLSR 683
+IL +N I F + RP +++P E+ RL
Sbjct: 167 ERILAMANKITFTVTRP--FQGLIRKP-----------------------DEDDTNRLGE 201
Query: 684 IDIANTLREQVQDLFNKKYGEAL 706
+ L+EQV++LFN+KY + L
Sbjct: 202 V----ILQEQVKELFNEKYSQCL 220
Score = 65.5 bits (158), Expect = 2e-10
Identities = 38/92 (41%), Positives = 54/92 (58%), Gaps = 2/92 (2%)
Query: 336 EKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDK 395
E +DA + + NTLRE VQ LFN Y EALG+ + V VPY+ I +P ++ I +P
Sbjct: 95 ENYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPG 154
Query: 396 IPFKRPCTYGVPKLKRILEERHSIHFIIKRMF 427
I F++P +G L+RIL + I F + R F
Sbjct: 155 ILFRKP--FGSQNLERILAMANKITFTVTRPF 184
Score = 60.5 bits (145), Expect = 7e-09
Identities = 38/118 (32%), Positives = 60/118 (50%), Gaps = 10/118 (8%)
Query: 96 PEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLR--------KMVEEVFDVLYSEALGRA 147
P A P++ R G SL R + D LLR + V+E+F+ Y EALG
Sbjct: 70 PPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYGEALGIK 129
Query: 148 SVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLE 205
V +PY+ + PG + ++ LP G+ FR+P + + L IL +++I F + RP +
Sbjct: 130 YPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVTRPFQ 185
Score = 45.8 bits (107), Expect = 2e-04
Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 6/79 (7%)
Query: 384 PEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRM------FDERIFTGNKF 437
PE + +VG+P+ I +RP +G+ KL +ILE +SI F+IKR E I
Sbjct: 3 PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62
Query: 438 TKDTTKLEPASPPEDTSAE 456
PA PPE S +
Sbjct: 63 ASSLGFSPPALPPERDSRD 81
Score = 40.0 bits (92), Expect = 0.010
Identities = 61/231 (26%), Positives = 93/231 (40%), Gaps = 33/231 (14%)
Query: 161 PGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGV 220
P L V GLPEG++ RRP + L ILE S+ I+F +KRP K L E
Sbjct: 3 PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP--------KLLTEGVKE 54
Query: 221 SLIPKGSRDCGLHGQAPKVPPQ---DLPPTATSSSMASFL--YSTALPN----HAIRELK 271
++ L P +PP+ P S F Y L + +RE
Sbjct: 55 PIVDSQGTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQV 114
Query: 272 QEAPSCPLAPSDLGLSRPMPEP-KATGAQDFSDCCGQKPTG-----PGGPLIQNVHASKR 325
QE + + LG+ P+ P K + S + P G P G QN+
Sbjct: 115 QELFNKTYGEA-LGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGS--QNLERILA 171
Query: 326 ILFSIVHDKSEKWDAFIKETEDINT-------LRECVQILFNSRYAEALGL 369
+ I + + I++ ++ +T L+E V+ LFN +Y++ L L
Sbjct: 172 MANKITFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWL 222
>gi|239749152 PREDICTED: similar to hCG1983816 [Homo sapiens]
Length = 265
Score = 350 bits (897), Expect = 5e-96
Identities = 201/296 (67%), Positives = 214/296 (72%), Gaps = 65/296 (21%)
Query: 596 MHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQ 655
MHPEELFVVGLPEGISLRRPNCFGIAKL KILEASNSIQFVIKRP+LLTEGVKEPIVDSQ
Sbjct: 1 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ 60
Query: 656 ---------------ERDSGDPLVDESLKRQGFQENYDARLSRIDIANTLREQVQDLFNK 700
ERDS DPLV ESLKRQGFQENYDARL RIDIANTLREQVQ+LFNK
Sbjct: 61 GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK 120
Query: 701 KYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKF 760
YGEALGIKYPVQVPYK IKSNPGS+IIE LPPGI FRKP FGSQNLERILA+A+KI F
Sbjct: 121 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITF 178
Query: 761 TVTRPFQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSP 820
TVTRPFQGLI KPDEDD NRLGE VIL+EQVKELFNEKY + L L
Sbjct: 179 TVTRPFQGLIRKPDEDDTNRLGE-VILQEQVKELFNEKYSQCLWL--------------- 222
Query: 821 DAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVP 876
L+ ++H I++ +PFAEICNDAKVP
Sbjct: 223 ----------------------------LQQQQH----HISEGRPFAEICNDAKVP 246
Score = 75.1 bits (183), Expect = 3e-13
Identities = 58/203 (28%), Positives = 88/203 (43%), Gaps = 34/203 (16%)
Query: 504 IQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPVEDSHGDVIR 563
++ + D T+ + S P P DS + L + L E D+
Sbjct: 52 VKEPIVDSQGTASSLGFSPPALPPERDS---RDPLVGESLKRQGFQENYDARLLRIDIAN 108
Query: 564 PLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKL 623
LR+QV+ LFN Y +A+GI PV+VPY +P + + LP GI R+P FG L
Sbjct: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166
Query: 624 RKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKRQGFQENYDARLSR 683
+IL +N I F + RP +++P E+ RL
Sbjct: 167 ERILAMANKITFTVTRP--FQGLIRKP-----------------------DEDDTNRLGE 201
Query: 684 IDIANTLREQVQDLFNKKYGEAL 706
+ L+EQV++LFN+KY + L
Sbjct: 202 V----ILQEQVKELFNEKYSQCL 220
Score = 65.5 bits (158), Expect = 2e-10
Identities = 38/92 (41%), Positives = 54/92 (58%), Gaps = 2/92 (2%)
Query: 336 EKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDK 395
E +DA + + NTLRE VQ LFN Y EALG+ + V VPY+ I +P ++ I +P
Sbjct: 95 ENYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPG 154
Query: 396 IPFKRPCTYGVPKLKRILEERHSIHFIIKRMF 427
I F++P +G L+RIL + I F + R F
Sbjct: 155 ILFRKP--FGSQNLERILAMANKITFTVTRPF 184
Score = 60.5 bits (145), Expect = 7e-09
Identities = 38/118 (32%), Positives = 60/118 (50%), Gaps = 10/118 (8%)
Query: 96 PEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLR--------KMVEEVFDVLYSEALGRA 147
P A P++ R G SL R + D LLR + V+E+F+ Y EALG
Sbjct: 70 PPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYGEALGIK 129
Query: 148 SVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLE 205
V +PY+ + PG + ++ LP G+ FR+P + + L IL +++I F + RP +
Sbjct: 130 YPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVTRPFQ 185
Score = 45.8 bits (107), Expect = 2e-04
Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 6/79 (7%)
Query: 384 PEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRM------FDERIFTGNKF 437
PE + +VG+P+ I +RP +G+ KL +ILE +SI F+IKR E I
Sbjct: 3 PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62
Query: 438 TKDTTKLEPASPPEDTSAE 456
PA PPE S +
Sbjct: 63 ASSLGFSPPALPPERDSRD 81
Score = 40.0 bits (92), Expect = 0.010
Identities = 61/231 (26%), Positives = 93/231 (40%), Gaps = 33/231 (14%)
Query: 161 PGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGV 220
P L V GLPEG++ RRP + L ILE S+ I+F +KRP K L E
Sbjct: 3 PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP--------KLLTEGVKE 54
Query: 221 SLIPKGSRDCGLHGQAPKVPPQ---DLPPTATSSSMASFL--YSTALPN----HAIRELK 271
++ L P +PP+ P S F Y L + +RE
Sbjct: 55 PIVDSQGTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQV 114
Query: 272 QEAPSCPLAPSDLGLSRPMPEP-KATGAQDFSDCCGQKPTG-----PGGPLIQNVHASKR 325
QE + + LG+ P+ P K + S + P G P G QN+
Sbjct: 115 QELFNKTYGEA-LGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGS--QNLERILA 171
Query: 326 ILFSIVHDKSEKWDAFIKETEDINT-------LRECVQILFNSRYAEALGL 369
+ I + + I++ ++ +T L+E V+ LFN +Y++ L L
Sbjct: 172 MANKITFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWL 222
>gi|239508897 PREDICTED: similar to hCG1983816 [Homo sapiens]
Length = 265
Score = 350 bits (897), Expect = 5e-96
Identities = 201/296 (67%), Positives = 214/296 (72%), Gaps = 65/296 (21%)
Query: 596 MHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQ 655
MHPEELFVVGLPEGISLRRPNCFGIAKL KILEASNSIQFVIKRP+LLTEGVKEPIVDSQ
Sbjct: 1 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ 60
Query: 656 ---------------ERDSGDPLVDESLKRQGFQENYDARLSRIDIANTLREQVQDLFNK 700
ERDS DPLV ESLKRQGFQENYDARL RIDIANTLREQVQ+LFNK
Sbjct: 61 GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK 120
Query: 701 KYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKF 760
YGEALGIKYPVQVPYK IKSNPGS+IIE LPPGI FRKP FGSQNLERILA+A+KI F
Sbjct: 121 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITF 178
Query: 761 TVTRPFQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSP 820
TVTRPFQGLI KPDEDD NRLGE VIL+EQVKELFNEKY + L L
Sbjct: 179 TVTRPFQGLIRKPDEDDTNRLGE-VILQEQVKELFNEKYSQCLWL--------------- 222
Query: 821 DAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVP 876
L+ ++H I++ +PFAEICNDAKVP
Sbjct: 223 ----------------------------LQQQQH----HISEGRPFAEICNDAKVP 246
Score = 75.1 bits (183), Expect = 3e-13
Identities = 58/203 (28%), Positives = 88/203 (43%), Gaps = 34/203 (16%)
Query: 504 IQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPVEDSHGDVIR 563
++ + D T+ + S P P DS + L + L E D+
Sbjct: 52 VKEPIVDSQGTASSLGFSPPALPPERDS---RDPLVGESLKRQGFQENYDARLLRIDIAN 108
Query: 564 PLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKL 623
LR+QV+ LFN Y +A+GI PV+VPY +P + + LP GI R+P FG L
Sbjct: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166
Query: 624 RKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKRQGFQENYDARLSR 683
+IL +N I F + RP +++P E+ RL
Sbjct: 167 ERILAMANKITFTVTRP--FQGLIRKP-----------------------DEDDTNRLGE 201
Query: 684 IDIANTLREQVQDLFNKKYGEAL 706
+ L+EQV++LFN+KY + L
Sbjct: 202 V----ILQEQVKELFNEKYSQCL 220
Score = 65.5 bits (158), Expect = 2e-10
Identities = 38/92 (41%), Positives = 54/92 (58%), Gaps = 2/92 (2%)
Query: 336 EKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDK 395
E +DA + + NTLRE VQ LFN Y EALG+ + V VPY+ I +P ++ I +P
Sbjct: 95 ENYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPG 154
Query: 396 IPFKRPCTYGVPKLKRILEERHSIHFIIKRMF 427
I F++P +G L+RIL + I F + R F
Sbjct: 155 ILFRKP--FGSQNLERILAMANKITFTVTRPF 184
Score = 60.5 bits (145), Expect = 7e-09
Identities = 38/118 (32%), Positives = 60/118 (50%), Gaps = 10/118 (8%)
Query: 96 PEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLR--------KMVEEVFDVLYSEALGRA 147
P A P++ R G SL R + D LLR + V+E+F+ Y EALG
Sbjct: 70 PPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYGEALGIK 129
Query: 148 SVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLE 205
V +PY+ + PG + ++ LP G+ FR+P + + L IL +++I F + RP +
Sbjct: 130 YPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVTRPFQ 185
Score = 45.8 bits (107), Expect = 2e-04
Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 6/79 (7%)
Query: 384 PEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRM------FDERIFTGNKF 437
PE + +VG+P+ I +RP +G+ KL +ILE +SI F+IKR E I
Sbjct: 3 PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62
Query: 438 TKDTTKLEPASPPEDTSAE 456
PA PPE S +
Sbjct: 63 ASSLGFSPPALPPERDSRD 81
Score = 40.0 bits (92), Expect = 0.010
Identities = 61/231 (26%), Positives = 93/231 (40%), Gaps = 33/231 (14%)
Query: 161 PGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGV 220
P L V GLPEG++ RRP + L ILE S+ I+F +KRP K L E
Sbjct: 3 PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP--------KLLTEGVKE 54
Query: 221 SLIPKGSRDCGLHGQAPKVPPQ---DLPPTATSSSMASFL--YSTALPN----HAIRELK 271
++ L P +PP+ P S F Y L + +RE
Sbjct: 55 PIVDSQGTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQV 114
Query: 272 QEAPSCPLAPSDLGLSRPMPEP-KATGAQDFSDCCGQKPTG-----PGGPLIQNVHASKR 325
QE + + LG+ P+ P K + S + P G P G QN+
Sbjct: 115 QELFNKTYGEA-LGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGS--QNLERILA 171
Query: 326 ILFSIVHDKSEKWDAFIKETEDINT-------LRECVQILFNSRYAEALGL 369
+ I + + I++ ++ +T L+E V+ LFN +Y++ L L
Sbjct: 172 MANKITFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWL 222
>gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens]
Length = 949
Score = 181 bits (459), Expect = 3e-45
Identities = 131/412 (31%), Positives = 189/412 (45%), Gaps = 43/412 (10%)
Query: 30 IITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCR 89
++T LVSAL+SMC L+K AEVAC+AV++ FVVGTE+G F+NAR + Q DF ++C
Sbjct: 22 VVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCV 81
Query: 90 GPPWKDPEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASV 149
+ + P + H + +LRK VE+ F Y +ALG +
Sbjct: 82 AEGLCEVKPPCPVNGMQ-------------VHSGETEILRKAVEDYFCFCYGKALGTTVM 128
Query: 150 VPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRP------ 203
VP+PYE++LR+ + VQGLPEG+AF+ P YD L ILE+ I F + RP
Sbjct: 129 VPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPES 188
Query: 204 -------LEDGGRDSKALVELNG---VSLIPKGSRDCGLHGQAPKVPPQDLPPTATSSSM 253
+ D R + E G V P L +A V + P +M
Sbjct: 189 QLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNM 248
Query: 254 ASFLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRPMPEPKATGAQDFSDCCGQKPTGPG 313
+ ++ N I S PL PS+ P E K G + S
Sbjct: 249 QG-SHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNS------ 301
Query: 314 GPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMV 373
V + ++ ++ E+ + E I LRE V LF+ ++ EA+G+D V
Sbjct: 302 ---AAGVEDLNIVQVTVPDNEKER----LSSIEKIKQLREQVNDLFSRKFGEAIGVDFPV 354
Query: 374 PVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKR 425
VPYRKI +P V I G+P + FK P + ++RILE I F + R
Sbjct: 355 KVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIR 406
Score = 118 bits (296), Expect = 2e-26
Identities = 99/324 (30%), Positives = 143/324 (44%), Gaps = 57/324 (17%)
Query: 351 LRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLK 410
LR+ V+ F Y +ALG MVPVPY K+ D AV + G+P+ + F+ P Y + LK
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
Query: 411 RILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPAS----PPEDTSAEVSRATVLDLA 466
ILE + I FII R F L P S P T AE S + +
Sbjct: 167 WILENKAGISFIINRPF----------------LGPESQLGGPGMVTDAERSIVSPSESC 210
Query: 467 GNARSDKGSMSEDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTS----------- 515
G M ED G E +K E ED + Q + P+S
Sbjct: 211 GPINVKTEPM-EDSGISLKAEAVS---VKKESEDPNYYQYNMQGSHPSSTSNEVIEMELP 266
Query: 516 -EEMTDSMPGHLPSED------------------SGYGMEMLTDKGLSEDARPEERPVED 556
E+ T +P P+ED S G+E D + + P+
Sbjct: 267 MEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVE---DLNIVQVTVPDNEKERL 323
Query: 557 SHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPN 616
S + I+ LR+QV LF+ ++ +AIG+ PVKVPY K +P + + G+P G+ + P
Sbjct: 324 SSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPG 383
Query: 617 CFGIAKLRKILEASNSIQFVIKRP 640
I+ +R+ILEA+ I+F + RP
Sbjct: 384 YLEISSMRRILEAAEFIKFTVIRP 407
Score = 111 bits (277), Expect = 4e-24
Identities = 93/336 (27%), Positives = 148/336 (44%), Gaps = 36/336 (10%)
Query: 558 HGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNC 617
H LRK VE F Y KA+G + V VPY K L + V GLPEG++ + P
Sbjct: 100 HSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPEN 159
Query: 618 FGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKRQGFQENY 677
+ +A L+ ILE I F+I RP L E G P + +R +
Sbjct: 160 YDLATLKWILENKAGISFIINRPFL-----------GPESQLGGPGMVTDAERSIVSPSE 208
Query: 678 DARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVP----YKRIKSNPGSVIIEGLPP 733
N E ++D EA+ +K + P Y S+P S E +
Sbjct: 209 SC-----GPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEM 263
Query: 734 GIPFRK-----PCTFGSQNLERILAVADKIKFT-VTRPFQGL---------IPKPDEDDA 778
+P P +++ E + + + VT G+ +P +++
Sbjct: 264 ELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERL 323
Query: 779 NRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPN 838
+ + + LREQV +LF+ K+GEA+G++ PV VPY+ I +P V + G+P + F+ P
Sbjct: 324 SSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPG 383
Query: 839 TYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAK 874
+I + +IL+A E ++ +I L P E+ N K
Sbjct: 384 YLEISSMRRILEAAEFIKFTVIRPL-PGLELSNVGK 418
Score = 106 bits (264), Expect = 1e-22
Identities = 55/128 (42%), Positives = 82/128 (64%), Gaps = 9/128 (7%)
Query: 675 ENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPG 734
+N RLS I+ LREQV DLF++K+GEA+G+ +PV+VPY++I NPG V+I+G+PPG
Sbjct: 317 DNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPG 376
Query: 735 IPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKPDEDDANRLGEKVILREQVKEL 794
+ F+ P ++ RIL A+ IKFTV RP GL + + +G++ I +Q +
Sbjct: 377 VVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGL-------ELSNVGKRKI--DQEGRV 427
Query: 795 FNEKYGEA 802
F EK+ A
Sbjct: 428 FQEKWERA 435
Score = 54.3 bits (129), Expect = 5e-07
Identities = 25/77 (32%), Positives = 44/77 (57%)
Query: 128 LRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALM 187
LR+ V ++F + EA+G V +PY ++ PG + + G+P G+ F+ P + ++
Sbjct: 332 LREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMR 391
Query: 188 AILEHSHRIRFKLKRPL 204
ILE + I+F + RPL
Sbjct: 392 RILEAAEFIKFTVIRPL 408
>gi|51241788 GTF2I repeat domain containing 2B [Homo sapiens]
Length = 949
Score = 181 bits (459), Expect = 3e-45
Identities = 131/412 (31%), Positives = 189/412 (45%), Gaps = 43/412 (10%)
Query: 30 IITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCR 89
++T LVSAL+SMC L+K AEVAC+AV++ FVVGTE+G F+NAR + Q DF ++C
Sbjct: 22 VVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCV 81
Query: 90 GPPWKDPEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASV 149
+ + P + H + +LRK VE+ F Y +ALG +
Sbjct: 82 AEGLCEVKPPCPVNGMQ-------------VHSGETEILRKAVEDYFCFCYGKALGTTVM 128
Query: 150 VPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRP------ 203
VP+PYE++LR+ + VQGLPEG+AF+ P YD L ILE+ I F + RP
Sbjct: 129 VPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPES 188
Query: 204 -------LEDGGRDSKALVELNG---VSLIPKGSRDCGLHGQAPKVPPQDLPPTATSSSM 253
+ D R + E G V P L +A V + P +M
Sbjct: 189 QLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNM 248
Query: 254 ASFLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRPMPEPKATGAQDFSDCCGQKPTGPG 313
+ ++ N I S PL PS+ P E K G + S
Sbjct: 249 QG-SHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNS------ 301
Query: 314 GPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMV 373
V + ++ ++ E+ + E I LRE V LF+ ++ EA+G+D V
Sbjct: 302 ---AAGVEDLNIVQVTVPDNEKER----LSSIEKIKQLREQVNDLFSRKFGEAIGVDFPV 354
Query: 374 PVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKR 425
VPYRKI +P V I G+P + FK P + ++RILE I F + R
Sbjct: 355 KVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIR 406
Score = 118 bits (296), Expect = 2e-26
Identities = 99/324 (30%), Positives = 143/324 (44%), Gaps = 57/324 (17%)
Query: 351 LRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLK 410
LR+ V+ F Y +ALG MVPVPY K+ D AV + G+P+ + F+ P Y + LK
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
Query: 411 RILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPAS----PPEDTSAEVSRATVLDLA 466
ILE + I FII R F L P S P T AE S + +
Sbjct: 167 WILENKAGISFIINRPF----------------LGPESQLGGPGMVTDAERSIVSPSESC 210
Query: 467 GNARSDKGSMSEDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTS----------- 515
G M ED G E +K E ED + Q + P+S
Sbjct: 211 GPINVKTEPM-EDSGISLKAEAVS---VKKESEDPNYYQYNMQGSHPSSTSNEVIEMELP 266
Query: 516 -EEMTDSMPGHLPSED------------------SGYGMEMLTDKGLSEDARPEERPVED 556
E+ T +P P+ED S G+E D + + P+
Sbjct: 267 MEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVE---DLNIVQVTVPDNEKERL 323
Query: 557 SHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPN 616
S + I+ LR+QV LF+ ++ +AIG+ PVKVPY K +P + + G+P G+ + P
Sbjct: 324 SSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPG 383
Query: 617 CFGIAKLRKILEASNSIQFVIKRP 640
I+ +R+ILEA+ I+F + RP
Sbjct: 384 YLEISSMRRILEAAEFIKFTVIRP 407
Score = 111 bits (277), Expect = 4e-24
Identities = 93/336 (27%), Positives = 148/336 (44%), Gaps = 36/336 (10%)
Query: 558 HGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNC 617
H LRK VE F Y KA+G + V VPY K L + V GLPEG++ + P
Sbjct: 100 HSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPEN 159
Query: 618 FGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKRQGFQENY 677
+ +A L+ ILE I F+I RP L E G P + +R +
Sbjct: 160 YDLATLKWILENKAGISFIINRPFL-----------GPESQLGGPGMVTDAERSIVSPSE 208
Query: 678 DARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVP----YKRIKSNPGSVIIEGLPP 733
N E ++D EA+ +K + P Y S+P S E +
Sbjct: 209 SC-----GPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEM 263
Query: 734 GIPFRK-----PCTFGSQNLERILAVADKIKFT-VTRPFQGL---------IPKPDEDDA 778
+P P +++ E + + + VT G+ +P +++
Sbjct: 264 ELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERL 323
Query: 779 NRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPN 838
+ + + LREQV +LF+ K+GEA+G++ PV VPY+ I +P V + G+P + F+ P
Sbjct: 324 SSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPG 383
Query: 839 TYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAK 874
+I + +IL+A E ++ +I L P E+ N K
Sbjct: 384 YLEISSMRRILEAAEFIKFTVIRPL-PGLELSNVGK 418
Score = 106 bits (264), Expect = 1e-22
Identities = 55/128 (42%), Positives = 82/128 (64%), Gaps = 9/128 (7%)
Query: 675 ENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPG 734
+N RLS I+ LREQV DLF++K+GEA+G+ +PV+VPY++I NPG V+I+G+PPG
Sbjct: 317 DNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPG 376
Query: 735 IPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKPDEDDANRLGEKVILREQVKEL 794
+ F+ P ++ RIL A+ IKFTV RP GL + + +G++ I +Q +
Sbjct: 377 VVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGL-------ELSNVGKRKI--DQEGRV 427
Query: 795 FNEKYGEA 802
F EK+ A
Sbjct: 428 FQEKWERA 435
Score = 54.3 bits (129), Expect = 5e-07
Identities = 25/77 (32%), Positives = 44/77 (57%)
Query: 128 LRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALM 187
LR+ V ++F + EA+G V +PY ++ PG + + G+P G+ F+ P + ++
Sbjct: 332 LREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMR 391
Query: 188 AILEHSHRIRFKLKRPL 204
ILE + I+F + RPL
Sbjct: 392 RILEAAEFIKFTVIRPL 408
>gi|239757552 PREDICTED: similar to hCG2006635, partial [Homo
sapiens]
Length = 304
Score = 66.2 bits (160), Expect = 1e-10
Identities = 35/81 (43%), Positives = 50/81 (61%)
Query: 129 RKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMA 188
+K VE+ F +AL + + VP+PYE++L++ L VQGLPEG+AF+ P YD L
Sbjct: 21 KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80
Query: 189 ILEHSHRIRFKLKRPLEDGGR 209
ILE++ I F +K E GR
Sbjct: 81 ILEYTAGISFIIKSSGEPQGR 101
Score = 50.4 bits (119), Expect = 8e-06
Identities = 29/73 (39%), Positives = 38/73 (52%)
Query: 566 RKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRK 625
+K VE F KA+ V VPY K L L V GLPEG++ + P + +A L
Sbjct: 21 KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80
Query: 626 ILEASNSIQFVIK 638
ILE + I F+IK
Sbjct: 81 ILEYTAGISFIIK 93
Score = 48.9 bits (115), Expect = 2e-05
Identities = 29/76 (38%), Positives = 41/76 (53%)
Query: 349 NTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPK 408
NT ++ V+ F +AL VPVPY K+ D A+ + G+P+ + FK P Y +
Sbjct: 18 NTRKKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLAT 77
Query: 409 LKRILEERHSIHFIIK 424
L+ ILE I FIIK
Sbjct: 78 LEWILEYTAGISFIIK 93
Score = 43.9 bits (102), Expect = 7e-04
Identities = 24/75 (32%), Positives = 40/75 (53%)
Query: 688 NTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQN 747
NT ++ V+D F +AL V VPY+++ + ++I++GLP G+ F+ P +
Sbjct: 18 NTRKKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLAT 77
Query: 748 LERILAVADKIKFTV 762
LE IL I F +
Sbjct: 78 LEWILEYTAGISFII 92
Score = 40.0 bits (92), Expect = 0.010
Identities = 23/78 (29%), Positives = 41/78 (52%)
Query: 788 REQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEK 847
++ V++ F +AL V VPY+ + A+ V GLP+ + F++P YD+ LE
Sbjct: 21 KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80
Query: 848 ILKAREHVRMVIINQLQP 865
IL+ + +I + +P
Sbjct: 81 ILEYTAGISFIIKSSGEP 98
>gi|239746033 PREDICTED: hypothetical protein XP_002344174 [Homo
sapiens]
Length = 145
Score = 65.5 bits (158), Expect = 2e-10
Identities = 33/74 (44%), Positives = 48/74 (64%)
Query: 129 RKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMA 188
+K VE+ F +AL + + VP+PYE++L++ L VQGLPEG+AF+ P YD L
Sbjct: 72 KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 131
Query: 189 ILEHSHRIRFKLKR 202
ILE++ I F +KR
Sbjct: 132 ILEYTAGISFIIKR 145
Score = 52.4 bits (124), Expect = 2e-06
Identities = 30/74 (40%), Positives = 39/74 (52%)
Query: 566 RKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRK 625
+K VE F KA+ V VPY K L L V GLPEG++ + P + +A L
Sbjct: 72 KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 131
Query: 626 ILEASNSIQFVIKR 639
ILE + I F+IKR
Sbjct: 132 ILEYTAGISFIIKR 145
Score = 50.8 bits (120), Expect = 6e-06
Identities = 30/77 (38%), Positives = 42/77 (54%)
Query: 349 NTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPK 408
NT ++ V+ F +AL VPVPY K+ D A+ + G+P+ + FK P Y +
Sbjct: 69 NTRKKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLAT 128
Query: 409 LKRILEERHSIHFIIKR 425
L+ ILE I FIIKR
Sbjct: 129 LEWILEYTAGISFIIKR 145
Score = 45.4 bits (106), Expect = 2e-04
Identities = 25/77 (32%), Positives = 41/77 (53%)
Query: 688 NTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQN 747
NT ++ V+D F +AL V VPY+++ + ++I++GLP G+ F+ P +
Sbjct: 69 NTRKKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLAT 128
Query: 748 LERILAVADKIKFTVTR 764
LE IL I F + R
Sbjct: 129 LEWILEYTAGISFIIKR 145
Score = 39.3 bits (90), Expect = 0.018
Identities = 29/103 (28%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 758 IKFTVTRPFQGLIPKPDEDDANRLGEKVILREQ-VKELFNEKYGEALGLNRPVLVPYKLI 816
+K T + + P E D R R++ V++ F +AL V VPY+ +
Sbjct: 41 LKQECTLIYHKKVYNPGESDECRCCRNGNTRKKTVEDYFCFCCRKALQKPTEVPVPYEKM 100
Query: 817 RDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVI 859
A+ V GLP+ + F++P YD+ LE IL+ + +I
Sbjct: 101 LQDQSALIVQGLPEGVAFKHPENYDLATLEWILEYTAGISFII 143
>gi|239752592 PREDICTED: hypothetical protein XP_002348308, partial
[Homo sapiens]
Length = 94
Score = 63.5 bits (153), Expect = 9e-10
Identities = 32/74 (43%), Positives = 47/74 (63%)
Query: 129 RKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMA 188
+K VE+ F + L + + VP+PYE++L++ L VQGLPEG+AF+ P YD L
Sbjct: 21 KKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80
Query: 189 ILEHSHRIRFKLKR 202
ILE++ I F +KR
Sbjct: 81 ILEYTAGISFIIKR 94
Score = 50.8 bits (120), Expect = 6e-06
Identities = 29/74 (39%), Positives = 38/74 (51%)
Query: 566 RKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRK 625
+K VE F K + V VPY K L L V GLPEG++ + P + +A L
Sbjct: 21 KKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80
Query: 626 ILEASNSIQFVIKR 639
ILE + I F+IKR
Sbjct: 81 ILEYTAGISFIIKR 94
Score = 49.3 bits (116), Expect = 2e-05
Identities = 29/77 (37%), Positives = 41/77 (53%)
Query: 349 NTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPK 408
NT ++ V+ F + L VPVPY K+ D A+ + G+P+ + FK P Y +
Sbjct: 18 NTRKKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLAT 77
Query: 409 LKRILEERHSIHFIIKR 425
L+ ILE I FIIKR
Sbjct: 78 LEWILEYTAGISFIIKR 94
Score = 43.1 bits (100), Expect = 0.001
Identities = 24/77 (31%), Positives = 40/77 (51%)
Query: 688 NTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQN 747
NT ++ V+D F + L V VPY+++ + ++I++GLP G+ F+ P +
Sbjct: 18 NTRKKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLAT 77
Query: 748 LERILAVADKIKFTVTR 764
LE IL I F + R
Sbjct: 78 LEWILEYTAGISFIIKR 94
Score = 38.1 bits (87), Expect = 0.039
Identities = 18/51 (35%), Positives = 29/51 (56%)
Query: 809 VLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVI 859
V VPY+ + A+ V GLP+ + F++P YD+ LE IL+ + +I
Sbjct: 42 VPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEWILEYTAGISFII 92
>gi|78486540 DDB1 and CUL4 associated factor 15 [Homo sapiens]
Length = 600
Score = 38.1 bits (87), Expect = 0.039
Identities = 44/174 (25%), Positives = 63/174 (36%), Gaps = 37/174 (21%)
Query: 429 ERIFTGNKFTKDTTKLEPASPPEDTSAEVSRAT--------------------------- 461
+R F + T L PASPPE S E+ A
Sbjct: 263 DRSFCQILYDHSTCPLAPASPPEPQSPELPPALPSFCPEAAPARSSGSPEPSPAIAKAKE 322
Query: 462 -VLDLAGNARSDKGSMSEDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTD 520
V D+ A+ KG + E+ P G R + E L + T P SP + E
Sbjct: 323 FVADIFRRAKEAKGGVPEEARPALCPGPSGSR-CRAHSEPLALCGETAPRDSPPASEAPA 381
Query: 521 SMPGHLPSE------DSGYGMEMLTDKGLSEDARPEERPVEDSHGDVIRPLRKQ 568
S PG++ +SG G E + L +D V D G +RP+R++
Sbjct: 382 SEPGYVNYTKLYYVLESGEGTE--PEDELEDDKISLPFVVTDLRGRNLRPMRER 433
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 37.4 bits (85), Expect = 0.067
Identities = 21/37 (56%), Positives = 27/37 (72%)
Query: 884 KRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQIS 920
KRKR+ S +S SSSSSSSSSSSS+ S +S++ S
Sbjct: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2638
Score = 36.6 bits (83), Expect = 0.11
Identities = 19/38 (50%), Positives = 28/38 (73%)
Query: 883 PKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQIS 920
P ++++R S +S SSSSSSSSSSSS+ S +S++ S
Sbjct: 2600 PAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2637
Score = 34.7 bits (78), Expect = 0.43
Identities = 21/53 (39%), Positives = 30/53 (56%)
Query: 868 EICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQIS 920
E + + P + KR+ S +S SSSSSSSSSSSS+ S +S++ S
Sbjct: 2588 EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2640
Score = 34.3 bits (77), Expect = 0.56
Identities = 19/45 (42%), Positives = 30/45 (66%)
Query: 873 AKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASAN 917
A+ P+ +++ K +R S +S SSSSSSSSSSSS+ S + ++
Sbjct: 2515 AQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSS 2559
Score = 34.3 bits (77), Expect = 0.56
Identities = 19/38 (50%), Positives = 26/38 (68%)
Query: 883 PKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQIS 920
P ++R+ S +S SSSSSSSSSSSS+ S S++ S
Sbjct: 2526 PAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDS 2563
Score = 32.3 bits (72), Expect = 2.1
Identities = 21/48 (43%), Positives = 27/48 (56%)
Query: 873 AKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQIS 920
AK + SS S +S SSSSSSSSSSSS+ S +S++ S
Sbjct: 2601 AKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648
Score = 31.6 bits (70), Expect = 3.6
Identities = 20/45 (44%), Positives = 25/45 (55%)
Query: 876 PAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQIS 920
PAK S +S SSSSSSSSSSSS+ S +S++ S
Sbjct: 2600 PAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644
Score = 30.8 bits (68), Expect = 6.2
Identities = 20/43 (46%), Positives = 27/43 (62%), Gaps = 4/43 (9%)
Query: 876 PAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQ 918
PAK+ +R S +S SSSSSSSSSSSS+ S +S ++
Sbjct: 2526 PAKE----RRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE 2564
>gi|169213965 PREDICTED: similar to hCG1645909 [Homo sapiens]
Length = 591
Score = 34.7 bits (78), Expect = 0.43
Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 5/85 (5%)
Query: 439 KDTTKLEPASPPEDTSAEVSRATV----LDLAGNARSDKGSMSEDCGPGTSGELGGLRPI 494
KDT P PPE S S ++ L L+GN+++ S S +S E P+
Sbjct: 368 KDTASKAPKDPPESHSLHRSSVSLDHCYLSLSGNSKAPSSS-SSSSSSSSSSEDSDSEPL 426
Query: 495 KIEPEDLDIIQVTVPDPSPTSEEMT 519
+ ED+ V P S E+ T
Sbjct: 427 WKQREDMQANPVGTPGSSEEDEDTT 451
>gi|239751822 PREDICTED: similar to hCG1645909 [Homo sapiens]
Length = 591
Score = 34.7 bits (78), Expect = 0.43
Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 5/85 (5%)
Query: 439 KDTTKLEPASPPEDTSAEVSRATV----LDLAGNARSDKGSMSEDCGPGTSGELGGLRPI 494
KDT P PPE S S ++ L L+GN+++ S S +S E P+
Sbjct: 368 KDTASKAPKDPPESHSLHRSSVSLDHCYLSLSGNSKAPSSS-SSSSSSSSSSEDSDSEPL 426
Query: 495 KIEPEDLDIIQVTVPDPSPTSEEMT 519
+ ED+ V P S E+ T
Sbjct: 427 WKQREDMQANPVGTPGSSEEDEDTT 451
>gi|239746313 PREDICTED: similar to hCG1645909 [Homo sapiens]
Length = 591
Score = 34.7 bits (78), Expect = 0.43
Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 5/85 (5%)
Query: 439 KDTTKLEPASPPEDTSAEVSRATV----LDLAGNARSDKGSMSEDCGPGTSGELGGLRPI 494
KDT P PPE S S ++ L L+GN+++ S S +S E P+
Sbjct: 368 KDTASKAPKDPPESHSLHRSSVSLDHCYLSLSGNSKAPSSS-SSSSSSSSSSEDSDSEPL 426
Query: 495 KIEPEDLDIIQVTVPDPSPTSEEMT 519
+ ED+ V P S E+ T
Sbjct: 427 WKQREDMQANPVGTPGSSEEDEDTT 451
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 34.7 bits (78), Expect = 0.43
Identities = 22/48 (45%), Positives = 27/48 (56%)
Query: 873 AKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQIS 920
A PA SS S +S SSSSSSSSSSSS+ S +S++ S
Sbjct: 2609 AASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
Score = 31.6 bits (70), Expect = 3.6
Identities = 19/41 (46%), Positives = 25/41 (60%)
Query: 880 SSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQIS 920
S+ R S +S SSSSSSSSSSSS+ S +S++ S
Sbjct: 2603 SAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
Score = 31.2 bits (69), Expect = 4.8
Identities = 20/51 (39%), Positives = 27/51 (52%)
Query: 870 CNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQIS 920
C+ A A + S +S SSSSSSSSSSSS+ S +S++ S
Sbjct: 2602 CSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2652
Score = 31.2 bits (69), Expect = 4.8
Identities = 20/56 (35%), Positives = 29/56 (51%)
Query: 865 PFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQIS 920
P + + + + SS S +S SSSSSSSSSSSS+ S +S++ S
Sbjct: 2612 PASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2667
Score = 30.8 bits (68), Expect = 6.2
Identities = 20/48 (41%), Positives = 26/48 (54%)
Query: 873 AKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQIS 920
A + SS S +S SSSSSSSSSSSS+ S +S++ S
Sbjct: 2610 ASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2657
Score = 30.4 bits (67), Expect = 8.1
Identities = 19/44 (43%), Positives = 25/44 (56%)
Query: 877 AKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQIS 920
+ SS S +S SSSSSSSSSSSS+ S +S++ S
Sbjct: 2625 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2668
Score = 30.4 bits (67), Expect = 8.1
Identities = 19/44 (43%), Positives = 25/44 (56%)
Query: 877 AKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQIS 920
+ SS S +S SSSSSSSSSSSS+ S +S++ S
Sbjct: 2626 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2669
Score = 30.4 bits (67), Expect = 8.1
Identities = 19/44 (43%), Positives = 25/44 (56%)
Query: 877 AKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQIS 920
+ SS S +S SSSSSSSSSSSS+ S +S++ S
Sbjct: 2627 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2670
Score = 30.4 bits (67), Expect = 8.1
Identities = 19/44 (43%), Positives = 25/44 (56%)
Query: 877 AKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQIS 920
+ SS S +S SSSSSSSSSSSS+ S +S++ S
Sbjct: 2628 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2671
>gi|66472382 nischarin [Homo sapiens]
Length = 1504
Score = 34.3 bits (77), Expect = 0.56
Identities = 40/166 (24%), Positives = 62/166 (37%), Gaps = 41/166 (24%)
Query: 180 EYDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGVSLIPKGSRDCGLHGQAPKV 239
E D ++ ++ + ++ KL P + GG DS+ AP +
Sbjct: 446 ELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRL--------------------SAAPCI 485
Query: 240 PPQDLPPTATSSSMASFLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRPMPEPKATGAQ 299
P PPT +S + L L N I +++EA + L+ +D P +P A G
Sbjct: 486 RPSSSPPTVAPASAS--LPQPILSNQGIMFVQEEALASSLSSTD--SLTPEHQPIAQGCS 541
Query: 300 D----------FSDCCGQKPTGPGG-------PLIQNVHASKRILF 328
D SD P GG P +Q V S +I+F
Sbjct: 542 DSLESIPAGQAASDDLRDVPGAVGGASPEHAEPEVQVVPGSGQIIF 587
>gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens]
Length = 352
Score = 34.3 bits (77), Expect = 0.56
Identities = 18/42 (42%), Positives = 27/42 (64%)
Query: 876 PAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASAN 917
P + ++ R+R +S SSSSSSSSSSSS+ S +S++
Sbjct: 173 PGAEERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSD 214
>gi|67010025 Sp4 transcription factor [Homo sapiens]
Length = 784
Score = 33.9 bits (76), Expect = 0.74
Identities = 21/58 (36%), Positives = 31/58 (53%)
Query: 880 SSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQISLVQWPMYMVDYAGLNVQ 937
S+ P K VS+ S SSSSSSS++ S++P S N + Q+ + V +VQ
Sbjct: 107 STPPASKENNVSQPASSSSSSSSSNNGSASPTKTKSGNSSTPGQFQVIQVQNPSGSVQ 164
>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 3 [Homo sapiens]
Length = 568
Score = 33.9 bits (76), Expect = 0.74
Identities = 35/121 (28%), Positives = 53/121 (43%), Gaps = 15/121 (12%)
Query: 812 PYKLIRDSPDAVEVTG-----LPDDIPFRNPNT-------YDIHRLEKILKAREHVRMVI 859
P ++ +D P VE +G LP ++ F+N YD+ + H+R
Sbjct: 62 PKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCEK 121
Query: 860 INQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQI 919
+ P + + K P R S +S SSSSSSSSSSSS+ S +S++
Sbjct: 122 LTFNNPTEDF---RRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 178
Query: 920 S 920
S
Sbjct: 179 S 179
Score = 31.2 bits (69), Expect = 4.8
Identities = 30/86 (34%), Positives = 37/86 (43%), Gaps = 13/86 (15%)
Query: 830 DDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKR 889
+ + F NP T D R K+LKA P I + + SS
Sbjct: 120 EKLTFNNP-TEDFRR--KLLKAGG----------DPNRSIHTSSSSSSSSSSSSSSSSSS 166
Query: 890 VSEGNSVSSSSSSSSSSSSNPDSVAS 915
S +S SSSSSSSSSSSS+ S S
Sbjct: 167 SSSSSSSSSSSSSSSSSSSSSSSSTS 192
Score = 30.8 bits (68), Expect = 6.2
Identities = 19/44 (43%), Positives = 25/44 (56%)
Query: 877 AKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQIS 920
+ SS S +S SSSSSSSSSSSS+ S +S++ S
Sbjct: 149 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTS 192
Score = 30.8 bits (68), Expect = 6.2
Identities = 19/44 (43%), Positives = 24/44 (54%)
Query: 877 AKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQIS 920
+ SS S +S SSSSSSSSSSSS+ S +S+ S
Sbjct: 151 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFS 194
>gi|27436957 membrane associated guanylate kinase, WW and PDZ domain
containing 2 [Homo sapiens]
Length = 1455
Score = 33.5 bits (75), Expect = 0.96
Identities = 38/136 (27%), Positives = 57/136 (41%), Gaps = 18/136 (13%)
Query: 436 KFTKDTTKLEPAS--PPEDTSAEVSRATVLDLAGNARSDKGSMSEDCGPGTSGELGGL-- 491
K K + +E AS PPE+ E V++ G + + S ED G SGE+
Sbjct: 216 KRNKSVSNMEKASIEPPEEEEEE---RPVVNGNGVVVTPESSEHEDKSAGASGEMPSQPY 272
Query: 492 -RPIKIEPEDL----DIIQVTVP------DPSPTSEEMTDSMPGHLPSEDSGYGMEMLTD 540
P+ +PE+L D + T P DP P + EM + G + D D
Sbjct: 273 PAPVYSQPEELKEQMDDTKPTKPEDNEEPDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLD 332
Query: 541 KGLSEDARPEERPVED 556
L++ A+P E E+
Sbjct: 333 PRLAKKAKPPEECKEN 348
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 33.5 bits (75), Expect = 0.96
Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 4/57 (7%)
Query: 864 QPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQIS 920
+PFAE+ ++ + IPK K K+ + SSSSSSSSSS S+ S + ++ S
Sbjct: 164 KPFAEV----RILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDS 216
>gi|50409691 SRp25 nuclear protein isoform 4 [Homo sapiens]
Length = 338
Score = 33.5 bits (75), Expect = 0.96
Identities = 18/34 (52%), Positives = 26/34 (76%)
Query: 884 KRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASAN 917
K+K +R + +S SSSSSSSSSSSS+ S +S++
Sbjct: 169 KQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSS 202
Score = 33.1 bits (74), Expect = 1.3
Identities = 19/39 (48%), Positives = 27/39 (69%)
Query: 877 AKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVAS 915
+++ S K +R+ S +S SSSSSSSSSSSS+ S +S
Sbjct: 164 SQERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSS 202
Score = 32.7 bits (73), Expect = 1.6
Identities = 17/34 (50%), Positives = 25/34 (73%)
Query: 884 KRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASAN 917
++ R+R +S SSSSSSSSSSSS+ S +S++
Sbjct: 170 QKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSD 203
Score = 30.8 bits (68), Expect = 6.2
Identities = 17/43 (39%), Positives = 25/43 (58%)
Query: 870 CNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDS 912
C+ + + +R+ + S +S SSSSSSSSSSSS+ S
Sbjct: 159 CSASTSQERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSS 201
>gi|50409707 SRp25 nuclear protein isoform 2 [Homo sapiens]
Length = 341
Score = 33.5 bits (75), Expect = 0.96
Identities = 18/34 (52%), Positives = 26/34 (76%)
Query: 884 KRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASAN 917
K+K +R + +S SSSSSSSSSSSS+ S +S++
Sbjct: 169 KQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSS 202
Score = 33.1 bits (74), Expect = 1.3
Identities = 19/39 (48%), Positives = 27/39 (69%)
Query: 877 AKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVAS 915
+++ S K +R+ S +S SSSSSSSSSSSS+ S +S
Sbjct: 164 SQERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSS 202
Score = 32.7 bits (73), Expect = 1.6
Identities = 17/34 (50%), Positives = 25/34 (73%)
Query: 884 KRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASAN 917
++ R+R +S SSSSSSSSSSSS+ S +S++
Sbjct: 170 QKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSD 203
Score = 30.8 bits (68), Expect = 6.2
Identities = 17/43 (39%), Positives = 25/43 (58%)
Query: 870 CNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDS 912
C+ + + +R+ + S +S SSSSSSSSSSSS+ S
Sbjct: 159 CSASTSQERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSS 201
>gi|50409756 SRp25 nuclear protein isoform 1 [Homo sapiens]
Length = 360
Score = 33.5 bits (75), Expect = 0.96
Identities = 18/34 (52%), Positives = 26/34 (76%)
Query: 884 KRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASAN 917
K+K +R + +S SSSSSSSSSSSS+ S +S++
Sbjct: 188 KQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSS 221
Score = 32.7 bits (73), Expect = 1.6
Identities = 17/34 (50%), Positives = 25/34 (73%)
Query: 884 KRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASAN 917
++ R+R +S SSSSSSSSSSSS+ S +S++
Sbjct: 189 QKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSD 222
Score = 32.3 bits (72), Expect = 2.1
Identities = 19/37 (51%), Positives = 25/37 (67%)
Query: 879 DSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVAS 915
+ S K +R+ S +S SSSSSSSSSSSS+ S +S
Sbjct: 185 ERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSS 221
Score = 31.6 bits (70), Expect = 3.6
Identities = 19/48 (39%), Positives = 26/48 (54%)
Query: 865 PFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDS 912
P AE + + +R+ + S +S SSSSSSSSSSSS+ S
Sbjct: 173 PGAEASPSPCITERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSS 220
Score = 30.4 bits (67), Expect = 8.1
Identities = 17/39 (43%), Positives = 25/39 (64%)
Query: 882 IPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQIS 920
I +R +++ SSSSSSSSSSSS+ S +S++ S
Sbjct: 183 ITERSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSS 221
>gi|32699028 V-set and immunoglobulin domain containing 1 [Homo
sapiens]
Length = 387
Score = 33.5 bits (75), Expect = 0.96
Identities = 31/130 (23%), Positives = 49/130 (37%), Gaps = 9/130 (6%)
Query: 437 FTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARSDKGSMSEDCGPGTSGELGGLRPIKI 496
F ++ K + T AE+ T + N R + +M + + +L P I
Sbjct: 256 FARNKAKAKAKERNSKTIAELEPMTKI----NPRGESEAMPRE----DATQLEVTLPSSI 307
Query: 497 EPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPVED 556
D IQ +P PT E + PG P +E+ + + PE P +
Sbjct: 308 HETGPDTIQEPDYEPKPTQEPAPEPAPGSEPMAVPDLDIELELEPETQSELEPEPEPEPE 367
Query: 557 SH-GDVIRPL 565
S G V+ PL
Sbjct: 368 SEPGVVVEPL 377
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.136 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,102,477
Number of Sequences: 37866
Number of extensions: 2040112
Number of successful extensions: 10505
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 9257
Number of HSP's gapped (non-prelim): 794
length of query: 944
length of database: 18,247,518
effective HSP length: 112
effective length of query: 832
effective length of database: 14,006,526
effective search space: 11653429632
effective search space used: 11653429632
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.