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Search of human proteins with 148746195
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148746195 trichohyalin [Homo sapiens]
(1943 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148746195 trichohyalin [Homo sapiens] 3808 0.0
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 342 3e-93
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 342 3e-93
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 342 3e-93
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 342 3e-93
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 342 3e-93
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 342 3e-93
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 342 3e-93
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 342 3e-93
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 335 3e-91
gi|21735548 centrosomal protein 2 [Homo sapiens] 322 2e-87
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 295 4e-79
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 283 1e-75
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 282 2e-75
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 262 3e-69
gi|221219020 NYD-SP11 protein [Homo sapiens] 258 3e-68
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 248 3e-65
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 238 3e-62
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 232 2e-60
gi|71061468 centromere protein E [Homo sapiens] 231 7e-60
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 228 4e-59
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 228 4e-59
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 228 4e-59
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 227 8e-59
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 219 2e-56
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 218 3e-56
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 215 4e-55
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 215 4e-55
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 215 4e-55
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 215 4e-55
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 3808 bits (9874), Expect = 0.0
Identities = 1943/1943 (100%), Positives = 1943/1943 (100%)
Query: 1 MSPLLRSICDITEIFNQYVSHDCDGAALTKKDLKNLLEREFGAVLRRPHDPKTVDLILEL 60
MSPLLRSICDITEIFNQYVSHDCDGAALTKKDLKNLLEREFGAVLRRPHDPKTVDLILEL
Sbjct: 1 MSPLLRSICDITEIFNQYVSHDCDGAALTKKDLKNLLEREFGAVLRRPHDPKTVDLILEL 60
Query: 61 LDLDSNGRVDFNEFLLFIFKVAQACYYALGQATGLDEEKRARCDGKESLLQDRRQEEDQR 120
LDLDSNGRVDFNEFLLFIFKVAQACYYALGQATGLDEEKRARCDGKESLLQDRRQEEDQR
Sbjct: 61 LDLDSNGRVDFNEFLLFIFKVAQACYYALGQATGLDEEKRARCDGKESLLQDRRQEEDQR 120
Query: 121 RFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEW 180
RFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEW
Sbjct: 121 RFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEW 180
Query: 181 QEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQE 240
QEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQE
Sbjct: 181 QEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQE 240
Query: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL 300
EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL
Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL 300
Query: 301 RREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR 360
RREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR
Sbjct: 301 RREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR 360
Query: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
Query: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480
REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480
Query: 481 EEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRR 540
EEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRR
Sbjct: 481 EEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRR 540
Query: 541 EQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQ 600
EQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQ
Sbjct: 541 EQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQ 600
Query: 601 RLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLK 660
RLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLK
Sbjct: 601 RLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLK 660
Query: 661 REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVY 720
REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVY
Sbjct: 661 REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVY 720
Query: 721 SRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERG 780
SRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERG
Sbjct: 721 SRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERG 780
Query: 781 RQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQL 840
RQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQL
Sbjct: 781 RQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQL 840
Query: 841 QRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR 900
QRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR
Sbjct: 841 QRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR 900
Query: 901 KEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQY 960
KEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQY
Sbjct: 901 KEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQY 960
Query: 961 RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQY 1020
RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQY
Sbjct: 961 RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQY 1020
Query: 1021 RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQY 1080
RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQY
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQY 1080
Query: 1081 RKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQY 1140
RKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQY
Sbjct: 1081 RKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQY 1140
Query: 1141 REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR 1200
REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR
Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR 1200
Query: 1201 EEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRD 1260
EEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRD
Sbjct: 1201 EEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRD 1260
Query: 1261 RQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQL 1320
RQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQL
Sbjct: 1261 RQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQL 1320
Query: 1321 LREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEE 1380
LREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEE
Sbjct: 1321 LREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEE 1380
Query: 1381 QRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVR 1440
QRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVR
Sbjct: 1381 QRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVR 1440
Query: 1441 RQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERD 1500
RQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERD
Sbjct: 1441 RQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERD 1500
Query: 1501 RKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE 1560
RKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE
Sbjct: 1501 RKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE 1560
Query: 1561 EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRK 1620
EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRK
Sbjct: 1561 EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRK 1620
Query: 1621 FREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGE 1680
FREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGE
Sbjct: 1621 FREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGE 1680
Query: 1681 EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL 1740
EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL
Sbjct: 1681 EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL 1740
Query: 1741 RRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREE 1800
RRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREE
Sbjct: 1741 RRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREE 1800
Query: 1801 EQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRRE 1860
EQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRRE
Sbjct: 1801 EQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRRE 1860
Query: 1861 EQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQF 1920
EQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQF
Sbjct: 1861 EQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQF 1920
Query: 1921 ASVPVRSSPLYEYIQEQRSQYRP 1943
ASVPVRSSPLYEYIQEQRSQYRP
Sbjct: 1921 ASVPVRSSPLYEYIQEQRSQYRP 1943
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 342 bits (876), Expect = 3e-93
Identities = 446/1785 (24%), Positives = 774/1785 (43%), Gaps = 216/1785 (12%)
Query: 114 RQEEDQRRFEPRDRQL-EEEPG----------QRRRQKRQEQER------ELAEGEEQSE 156
R +D F P DR + E E G Q Q QE+ R EL + Q E
Sbjct: 938 RDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGAQEESRCQRCISELKDIRLQLE 997
Query: 157 KQE-RLEQRDRQRRDEELWRQ-RQEWQEREERRAEEEQL------QSCKGHETEEFPDEE 208
E R R R D+E R+ Q E+++ +AE E L S + + P+
Sbjct: 998 ACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPS 1057
Query: 209 QL--RRRELLELRRKGREEKQQQRRERQDRVFQEEEE------KEWRKRETVLRKEEEKL 260
R LEL E+ + ++ E+ + + + E VLR EE+L
Sbjct: 1058 PAAPTLRSELELTLGKLEQVRS-----LSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQL 1112
Query: 261 QEEE--PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318
+E + P EL+ + L+KL R + ++ + + LR Q++ + ++ E+
Sbjct: 1113 KEAQAVPATLPELEATKASLKKL-RAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERD 1171
Query: 319 EERREQQERREQQEERREQQLRREQEERRE-QQLRREQEEERRE-QQLRREQEEERREQQ 376
E +ER Q ER + L + +RE +QL R+ R L ++ RR Q+
Sbjct: 1172 VEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQE 1231
Query: 377 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE---- 432
+ L Q +R +QLR+EQ L E + R + E Q +Q + ++ E
Sbjct: 1232 QIQAMPLADSQAVR--EQLRQEQALLEE--IERHGEKVEECQRFAKQYINAIKDYELQLV 1287
Query: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR----------KQQLKRDQEE 482
++ + E + + Q ++ + H E + L+R +EE
Sbjct: 1288 TYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEE 1347
Query: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
ER + EE ER + E ++ R+ E + + + + E + LQQR++ E+ +RRE+
Sbjct: 1348 ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ-EEVVRREE 1406
Query: 543 EERREQLLKREEEKRLEQERRE-----QRLKREQEERRDQLLKREEERRQQRLKREQEER 597
Q KR ++ L+Q R+ Q R+ E L+ EEE R RL+ E ER
Sbjct: 1407 AAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATER 1466
Query: 598 -----------LEQRLKREEVERLEQEERREQRLKREEPEEERRQQ----LLKSEEQEER 642
L R + E ++ + +E E+ ++ + E +R++Q L + E
Sbjct: 1467 QRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAE 1526
Query: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIP 702
++ +R Q E RL+ EE E RL Q E E R+ Q E Q A ++S+
Sbjct: 1527 AAREKQRALQALEELRLQAEEAERRLRQ---AEVERARQVQVALETAQRSAEAELQSKRA 1583
Query: 703 KW-QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES---ELQ-WQ---EEERA 754
+ + + E ++ V ++E +RR Q+Q E R RE EL+ WQ E
Sbjct: 1584 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1643
Query: 755 HRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE- 813
R Q EE ++ Q +AE++ E + R EQ RQ E++ +QR L E
Sbjct: 1644 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEG 1703
Query: 814 --------EEEKEQRRRQRREREKELQFLEEE-EQLQRR-----ERAQQLQEEEDGLQED 859
E+E + R + + E++ Q LEEE +LQR ++ Q+L+ E ++ +
Sbjct: 1704 TAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAE 1763
Query: 860 QE-----RRRSQEQRR--DQKWRWQLEEERKRRRHTLYAKP---ALQEQLRKEQQLLQEE 909
E + R++E+ R +K + +LE E R R AL E+ ++++Q L EE
Sbjct: 1764 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQ-LAEE 1822
Query: 910 EEELQREEREK-------------RRRQEQERQYREEEQLQQEEEQLLREEREKRRR--- 953
+ QR E E+ R + E E +E+E + +L +E +RRR
Sbjct: 1823 DAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEE 1882
Query: 954 ---------QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
+ER Q RK + + ++ L E+ ++RRQ E+ + ++
Sbjct: 1883 QAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKA 1942
Query: 1005 REEREKRR-RQEWERQYRKKD--ELQQEEEQLLREEREKRRLQERERQYR----EEEELQ 1057
E E R R E R K+ EL+ ++ L E E+RR + ER + EEE +
Sbjct: 1943 ELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR 2002
Query: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117
Q + L ER + +E R + E+ + QL +E +KR + E + ++ +
Sbjct: 2003 QRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 2062
Query: 1118 QEEEQLLREERE--KRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175
QE +Q L++E+ + R E E R EE ++ Q RE + R RQ E E
Sbjct: 2063 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR------RQVEEAER 2116
Query: 1176 LQQE-EEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234
L+Q EEQ Q + E+ R+ E+E +R + +Q + Q +D E EK
Sbjct: 2117 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADA----EMEKHKK 2172
Query: 1235 VRDNKVYCKGRENEQFR----QLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRD 1290
+ + K + ++ QLE++ + ++LQ L E E R++ + +
Sbjct: 2173 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2232
Query: 1291 RHFPEEEQLEREEQKEAKRRD---RKSQEEKQLLREEREEKRRRQETDRKF----REEEQ 1343
EE + + + EA+ R R ++ L+EE E+ ++ E + +E +
Sbjct: 2233 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2292
Query: 1344 LLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQE 1403
L Q EE +++ K +E+++ ++ + E + L++Q K L +EQ R QE
Sbjct: 2293 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQ----KELAQEQARRLQE 2348
Query: 1404 REQQLRQDRDRKF----------REEEQQLSRQERDRKFREEEQ---QVRRQERERKFLE 1450
++Q+ Q + R+ + ++S + K R E Q R +E ++F +
Sbjct: 2349 DKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRK 2408
Query: 1451 EEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE--- 1507
+ +++ ++ HR ++ + + ++ RQ+ D + + ER+++ +QE
Sbjct: 2409 QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKL 2468
Query: 1508 LRSQEPERKFLEEEQQLHRQQR-QRKFLQEEQQLRRQERG-QQRRQDRDRKFREE----E 1561
L+ + E + +++EQ L Q Q+ FL E+ L ++ER +Q + ++ F++E +
Sbjct: 2469 LQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQ 2528
Query: 1562 QLRQERE-EQQLSRQERDRKFRLEEQKVRRQ----EQERKFMEDEQQLRRQEGQQ-QLRQ 1615
QLR+E++ +QQ QER R E+ RRQ E R+ E+ QQL +Q QQ +L
Sbjct: 2529 QLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLA 2588
Query: 1616 ERDRKFREDEQLLQEREEQQLHRQER--------DRKFLEEEPQLRRQEREQQLRHDRDR 1667
E +++ RE QLL+E+ L E + L E + H D
Sbjct: 2589 EENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDG 2648
Query: 1668 KFRE-EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ 1711
R+ Q LQE +R + +L R+E R +LQ
Sbjct: 2649 LRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQ 2693
Score = 326 bits (836), Expect = 1e-88
Identities = 360/1355 (26%), Positives = 617/1355 (45%), Gaps = 193/1355 (14%)
Query: 113 RRQEEDQR-----RFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQ 167
RR EE++R R E R+R E E E++R+LAE Q++ Q E ++ Q
Sbjct: 1342 RRMEEEERLAEQQRAEERERLAEVEAA-------LEKQRQLAEAHAQAKAQAEREAKELQ 1394
Query: 168 RR--DEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE- 224
+R +E + R+ ++++R+ +E+LQ QLR+ E++ K R+
Sbjct: 1395 QRMQEEVVRREEAAVDAQQQKRSIQEELQ--------------QLRQSSEAEIQAKARQA 1440
Query: 225 ---EKQQQRRERQDRVFQEEEEKEWRKR---ETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
E+ + R E + RV + + E R+R E L+ + +E E Q+ R+ QEE E+L
Sbjct: 1441 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK-RQAQEEAERL 1499
Query: 279 RKLERQELRRERQEEEQQQQRLRREQQLRRKQE------EERREQQEERREQQERREQQE 332
R+ + E +R+RQ E + R++ E + R+++ EE R Q EE E++ R+ + E
Sbjct: 1500 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE-AERRLRQAEVE 1558
Query: 333 ERREQQLRREQEER---REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
R+ Q+ E +R E Q +R E+ Q R QEE QLR E + R +QQ
Sbjct: 1559 RARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQA 1618
Query: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
E+ ++ QL+ + LR Q Q + + E +QK E ER +R +
Sbjct: 1619 EAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGK 1678
Query: 450 EQEE---RRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506
+E+ +R+ ++E E +R E QQ ++E R L+ E E+ +Q++ E++
Sbjct: 1679 AEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR---LRAETEQGEQQRQLLEEE 1735
Query: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566
L R Q E KRQE E L ++R E E + EEE R E+ +QR
Sbjct: 1736 LARLQREAAAATQKRQELEAEL-------AKVRAEMEVLLASKARAEEESRSTSEKSKQR 1788
Query: 567 LKRE------------------QEERRDQLLKREEERRQQ------------------RL 590
L+ E +E +R + L E+ RQ+ RL
Sbjct: 1789 LEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRL 1848
Query: 591 KREQEERL-EQRLKREEVERLEQEERREQRLKREEPE------EERRQQLLKSEEQEERR 643
K E E L E+ + E + RL ++E ++R E+ EER QL K+ + E R
Sbjct: 1849 KTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELER 1908
Query: 644 QQQL------RREQQERREQRLK--------------------REEEEERLEQRLKREHE 677
Q+ L +R Q E LK R E+ L + + E E
Sbjct: 1909 QKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELE 1968
Query: 678 EERREQELAEEE--QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQ 735
R+ Q AEEE + +A ER++ + + + + A +V K E RR +E+
Sbjct: 1969 AARQRQLAAEEERRRREAEERVQKSLAA-EEEAARQRKAALEEVERLKAKVEEARRLRER 2027
Query: 736 EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRE 795
E+ R+ +L +E A ++ Q EE+ F Q + +E + +Q S LR + E
Sbjct: 2028 AEQESARQLQL---AQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2084
Query: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDG 855
RA E + E+ + E E Q RRQ E E+ Q EEQ Q R +AQ E+
Sbjct: 2085 AARRAAE--EAEEARVQAEREAAQSRRQVEEAERLKQ--SAEEQAQARAQAQAAAEKLRK 2140
Query: 856 LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL----LQEEEE 911
E + RR+Q ++ + + + E + +H +A+ L+++ + EQ+L LQ EE
Sbjct: 2141 EAEQEAARRAQAEQAALRQKQAADAEME--KHKKFAEQTLRQKAQVEQELTTLRLQLEET 2198
Query: 912 ELQR---EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
+ Q+ +E +R + E R+ Q+++E + + E + + R + L+
Sbjct: 2199 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD 2258
Query: 969 KE--EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
K+ ++ L EE EK ++ E + + L EE ++R E+ ++K +
Sbjct: 2259 KDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQA 2318
Query: 1027 QQEEEQLLRE----EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK 1082
QE +L E +++K QE+ R+ +E++E Q +QL E + +R E ERQ +
Sbjct: 2319 VQEATRLKAEAELLQQQKELAQEQARRLQEDKE--QMAQQLAEETQGFQRTLEAERQ--R 2374
Query: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYRE 1142
+ E+ E E+L E R Q R EE+ Q+ +Q E EK R EL Q +
Sbjct: 2375 QLEMSAEAERLKLRVAEMSR-----AQARAEEDAQRFRKQ-AEEIGEKLHRTELATQEKV 2428
Query: 1143 EEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREE 1202
E ++ + +R R+ + RE+E+LQQE + L + +E + ++E+ +E
Sbjct: 2429 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQET 2488
Query: 1203 EELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQ 1262
+ LQ Q + E + S L+ + E+E A + + + +Q R E+ Q + +Q
Sbjct: 2489 QALQ-----QSFLSE-KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR--EEQQRQQQQ 2540
Query: 1263 SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR 1322
+Q+ Q L+ +E R Q E E+ R +Q+E ++ +++ +++++LL
Sbjct: 2541 MEQERQRLVASMEEARRRQH------------EAEEGVRRKQEELQQLEQQRRQQEELLA 2588
Query: 1323 EEREEKRRRQETDRKFREEEQLLQEREEQPLRRQE 1357
EE +++ RE+ QLL+E+ L E
Sbjct: 2589 EE----------NQRLREQLQLLEEQHRAALAHSE 2613
Score = 324 bits (830), Expect = 6e-88
Identities = 461/1845 (24%), Positives = 811/1845 (43%), Gaps = 259/1845 (14%)
Query: 253 LRKEEEK--LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQ 310
L+ EE++ L E Q L++ ++ L ER+ + Q L +
Sbjct: 917 LKPEEQRQALHSLELHYQAFLRDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGA 976
Query: 311 EEERREQQ--EERREQQERREQQEERREQQLR--------REQEERREQQLRREQEEERR 360
+EE R Q+ E ++ + + E E R +LR RE +R +Q + + E E
Sbjct: 977 QEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGL 1036
Query: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
+ + R E E+ L + LR E +L L + +Q+R + E+
Sbjct: 1037 GKGVARLSAEA--EKVLALPEPSPAAPTLRSELELT----LGKLEQVRSLSAIYLEKLKT 1090
Query: 421 REQQLRREQEEERHEQKHEQERREQRLKR----EQEERRDWLKR---EEETERHEQERRK 473
+R Q E + HE++ +E + E E + LK+ + E ++ + +
Sbjct: 1091 ISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALR 1150
Query: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
+L+ QE R + E + E+ R QL + Q RQ E E+L ++LR
Sbjct: 1151 DELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLR 1210
Query: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE 593
+ E + L ++ R QE+ + + + R+QL R+E+ + ++R
Sbjct: 1211 YYR-------ESADPLGAWLQDARRRQEQIQAMPLADSQAVREQL--RQEQALLEEIERH 1261
Query: 594 QEERLE-QRLKREEVERLEQEERREQRLKRE-EP--EEERRQQLLKSEEQEERRQQQLRR 649
E+ E QR ++ + ++ E + K + EP ++ ++ E + LR
Sbjct: 1262 GEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRT 1321
Query: 650 EQQERR----------EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
E + L+R EEEERL ++ + E E E E A E+Q Q
Sbjct: 1322 HYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQL------ 1375
Query: 700 RIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQ- 758
+EA A+ R K+ QR QEE RR E+ + Q+++R+ +++
Sbjct: 1376 ----------AEAHAQAKAQAEREAKELQQRM---QEEVVRREEAAVDAQQQKRSIQEEL 1422
Query: 759 QEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQ-----REQRFLPE 813
Q+ Q + Q +A + R RL +R R QL A ERQ+ Q
Sbjct: 1423 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVR-LQLEATERQRGGAEGELQALRAR 1481
Query: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRR----ERAQQLQEEEDGLQEDQERRRSQEQR 869
EE E ++RQ +E + L+ ++E ++R E A +++ E + +E Q ++ E+
Sbjct: 1482 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1541
Query: 870 RDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQ 929
R Q EE +R R A E+ R+ Q L+ + + E + KR E+
Sbjct: 1542 R-----LQAEEAERRLRQ------AEVERARQVQVALETAQRSAEAELQSKRA-SFAEKT 1589
Query: 930 YREEEQLQQEEEQL--LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE 987
+ E LQ+E + LREE E+R +Q+ E + +++ ++ E L R R + E
Sbjct: 1590 AQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE 1649
Query: 988 KKYREEEELQQEEEQLLRE-EREKRRRQEWERQYRKKDELQQEE------------EQLL 1034
+ +++ Q E E+ E ERE RRR + E Q ++ EL ++E +Q L
Sbjct: 1650 EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRL 1709
Query: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERE--TRRRQELERQYRKEEELQQEEEQ 1092
E+E RL+ Q ++ +L +EE L E T++RQELE + K ++ E E
Sbjct: 1710 AAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK---VRAEMEV 1766
Query: 1093 LL----REEPEKRRRQERERQCREEE-----ELQQEEEQL--LREEREKRRR---QELER 1138
LL R E E R E+ +Q E E EL +E +L L EE +++R+ ++ R
Sbjct: 1767 LLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAAR 1826
Query: 1139 QYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE--QEKRRQERE 1196
Q E E V E+ + E R + E E +E+E + +L +E Q +R +E+
Sbjct: 1827 QRAEAERVLAEKLAAIGEAT--RLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQA 1884
Query: 1197 RQYREE-EELQRQKRK----QRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFR 1251
Q++ + EE Q RK + R + D Q +E + + K +
Sbjct: 1885 AQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAEL 1944
Query: 1252 QLEDSQLRDR-----QSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE 1306
+LE ++R +S++ + Q++ E+ERRR + +R ++ L EE E
Sbjct: 1945 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER---VQKSLAAEE--E 1999
Query: 1307 AKRRDRKSQEEKQLLREEREEKRR-RQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365
A R+ + + EE + L+ + EE RR R+ +++ + QL QE ++ L+ +E+ F +
Sbjct: 2000 AARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ 2059
Query: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425
+ + Q + L++EQ + Q R + E R E ++ R +R+ + +Q+
Sbjct: 2060 QKEQELQ--QTLQQEQSVLDQLRG----EAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2113
Query: 1426 QERDRKFREEEQQVR--------------RQERERKFLEEEQQLRQ--------ERHRKF 1463
ER ++ EE+ Q R QE R+ E+ LRQ E+H+KF
Sbjct: 2114 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2173
Query: 1464 REEEQLLQEREEQ-------QLHRQERDRKFLEEEQQLRRQE-----RDRKFREQELRSQ 1511
E+ + + EQ QL + + L+EE Q + E R R E+EL S
Sbjct: 2174 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2233
Query: 1512 EPERKFLEEEQQLHRQQRQRKFLQEEQQLRR--QERGQQRRQDRDRKFR------EEEQL 1563
+ + L + + + + L+++ +R QE ++ +Q + R E +L
Sbjct: 2234 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2293
Query: 1564 RQEREE---QQLSRQERDRKFR----------------LEEQKVRRQEQERKFMEDEQQL 1604
RQ EE QQ + E+ K + L++QK QEQ R+ ED++Q+
Sbjct: 2294 RQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQM 2353
Query: 1605 RRQEGQQQLRQERDRKFREDEQLLQEREEQQLH----RQERDRKFLEEEPQLRRQEREQ- 1659
+Q ++ +R + QL E ++L R + EE+ Q R++ E+
Sbjct: 2354 AQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2413
Query: 1660 -QLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQ---Q 1715
+ H + +E+ L+Q E ++RQ+ D + + ERE++ LQ+E Q
Sbjct: 2414 GEKLHRTELATQEKVTLVQTLE---IQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2470
Query: 1716 LRRQELERKFREEEQLRQET---------EQEQLRRQERYRKILEEEQLRPE---REEQQ 1763
L+ +E++ ++EQL QET E++ L ++ER+ +E+E+ + E ++E
Sbjct: 2471 LKSEEMQTV--QQEQLLQETQALQQSFLSEKDSLLQRERF---IEQEKAKLEQLFQDEVA 2525
Query: 1764 LRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE-EEQLRQEREE-QQLRPQQRDGKY 1821
+Q R+ + R+++Q+ QER+ +E+ R+ E EE +R+++EE QQL Q+R +
Sbjct: 2526 KAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEE 2585
Query: 1822 RWEEEQLQLEEQEQRL-RQERDRQYRAEEQFATQEKSRR-------------EEQELWQE 1867
EE +L EQ Q L Q R +EE A+Q + + E E
Sbjct: 2586 LLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHS 2645
Query: 1868 EEQKRRQERERKLREEHI---RRQQKEEQRHRQVGEIKSQEGKGH 1909
+ RR+ ++L+E I Q+ Q H V E+ +E H
Sbjct: 2646 FDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRH 2690
Score = 321 bits (822), Expect = 5e-87
Identities = 452/1778 (25%), Positives = 777/1778 (43%), Gaps = 303/1778 (17%)
Query: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ--LRREQQL-----------RR 421
Q LRR+ QL R L + L+ E+Q + L Q LR Q R
Sbjct: 897 QSLRRDVQLIRSWSLATFRTLKPEEQRQALHSLELHYQAFLRDSQDAGGFGPEDRLMAER 956
Query: 422 E------------QQLRREQEEERHEQKHEQERREQRLKREQEERRDW----LKREEETE 465
E Q L + +EE Q+ E ++ RL+ E E R L ++E
Sbjct: 957 EYGSCSHHYQQLLQSLEQGAQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPA 1016
Query: 466 RHEQERRKQQLKRDQEEE-----------RRERWLKLEEEERREQQERREQQLRREQ-EE 513
R +R +Q K E E E+ L L E R E +L + E+
Sbjct: 1017 RECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQ 1076
Query: 514 RREQRLKRQEEEERLQQRLR----SEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
R E+ + + +R +E+ LR +E+ +E LE + + R
Sbjct: 1077 VRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLR 1136
Query: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER 629
Q E + + R + R +E ERL+QR +VE ER Q L ER
Sbjct: 1137 AQAEAQQPTF--DALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLL-------ER 1187
Query: 630 RQQLLKSEEQEERRQQQLRREQQERRE---------QRLKREEEE---------ERLEQR 671
Q +L + +R +QL R+ + RE Q +R +E+ + + ++
Sbjct: 1188 WQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQ 1247
Query: 672 LKREH---EEERREQELAEEEQEQARERIKS------RIPKWQWQLESEADARQSKVYSR 722
L++E EE R E EE Q A++ I + ++ ++ QLE A + +
Sbjct: 1248 LRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK-----K 1302
Query: 723 PRKQEGQRRRQEQEEKRRRRESEL----------------QWQEEERAHRQQQEEEQRRD 766
P+ Q G ++ R SEL + +EEER QQ+ EE+ R
Sbjct: 1303 PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER- 1361
Query: 767 FTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQR-EQRFLPEEEEKEQRRRQRR 825
+ E E+ RQ A + Q ER+ A+E QQR ++ + EE ++Q+R
Sbjct: 1362 ---LAEVEAALEKQRQLAEAHAQAKAQAERE--AKELQQRMQEEVVRREEAAVDAQQQKR 1416
Query: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR 885
++ELQ L + + + + +A+Q + E + R R +E+ R R QLE ++R
Sbjct: 1417 SIQEELQQLRQSSEAEIQAKARQAEAAE------RSRLRIEEEIRVV--RLQLEATERQR 1468
Query: 886 ---RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQER------------QY 930
L A A E+ +++ QEE E L+R+ +++ +R+ Q
Sbjct: 1469 GGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAA 1528
Query: 931 REEEQLQQ--EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK 988
RE+++ Q EE +L EE E+R RQ + R+ + + ++ E + +R EK
Sbjct: 1529 REKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEK 1588
Query: 989 KYREEEELQQEEEQL--LREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
+ E LQ+E + LREE E+R +Q+ E + R ++E ++E E+ + E RL+ +
Sbjct: 1589 TAQLERSLQEEHVAVAQLREEAERRAQQQAEAE-RAREEAERELERWQLKANEALRLRLQ 1647
Query: 1047 ERQYREEEELQQEEEQLLGEE--RETRRRQELERQYRKEEELQQEE----EQLLREEPEK 1100
+ +++ L Q E + EE RE RRR + E Q ++ EL ++E QL ++
Sbjct: 1648 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1707
Query: 1101 RRRQERER-QCREEEELQQEEEQLLREEREK---------RRRQELERQYREEEEVQQEE 1150
R E+E + R E E +++ QLL EE + ++RQELE E +V+ E
Sbjct: 1708 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA---ELAKVRAEM 1764
Query: 1151 EQLL----REEPEKRRRQELERQYREEE-----ELQQEEEQLLREEQEKRRQERERQYRE 1201
E LL R E E R E +Q E E EL +E +L +E +RQ RQ E
Sbjct: 1765 EVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ---RQLAE 1821
Query: 1202 EEELQRQKRKQRYRDEDQRS-DLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQL-- 1258
E+ +++ +R E + + + E E A+++ K ENE+ R+L + +
Sbjct: 1822 EDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKE-----KEAENERLRRLAEDEAFQ 1876
Query: 1259 RDRQSQQDLQH-------LLGEQQERDREQERRRWQQRD----RHFPEEEQLEREEQKEA 1307
R R +Q QH L ++ D E ER++ D R EEE L + E
Sbjct: 1877 RRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEK 1936
Query: 1308 KR-----------RDRKSQEEKQLLREEREEKRRRQ-----ETDRKFREEEQLLQEREEQ 1351
R R + E+ +E+ E + RQ E +R+ RE E ER ++
Sbjct: 1937 AAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE----ERVQK 1992
Query: 1352 PLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR-------------QERERKFLKEEQQ 1398
L +E + R+ L E+ + +EE +RLR QE +K L+ E++
Sbjct: 1993 SLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEK 2052
Query: 1399 LRC---QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ-ERE----RKFLE 1450
Q++EQ+L+Q ++ +Q E R+ EE ++ R Q ERE R+ +E
Sbjct: 2053 AHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2112
Query: 1451 EEQQLRQERHRKFREE-------EQLLQEREEQQLHRQERDRKFLEEEQQLRRQ-ERDRK 1502
E ++L+Q + + E+L +E E++ R + ++ L ++Q + E+ +K
Sbjct: 2113 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2172
Query: 1503 FREQELRSQ-EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561
F EQ LR + + E++ QL Q+ L EE Q + E + RQ R EEE
Sbjct: 2173 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQ---RSQVEEE 2229
Query: 1562 QLRQEREEQQLSRQERDRKFRLEEQK----VRRQEQERKFMEDEQQLRRQEGQQQLRQER 1617
+ ++LS+ K R+E + +R ++ ++F+++E + +Q ++ R
Sbjct: 2230 LFSVRVQMEELSKL----KARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV 2285
Query: 1618 DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQ 1677
+ E +L Q EE ++ K L+E+ Q ++ + + E +LLQ
Sbjct: 2286 AAQ--EAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT----------RLKAEAELLQ 2333
Query: 1678 EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ 1737
+ +E QE+ R+ +E+++Q+ +Q L EE Q ++ LE + + + ++ E E+
Sbjct: 2334 QQKELA---QEQARRLQEDKEQMAQQ------LAEETQGFQRTLEAERQRQLEMSAEAER 2384
Query: 1738 EQLRRQERYRKILEEEQLRPEREEQQLRRQERD--RKFREEEQLRQER----EEQQLRSQ 1791
+LR E R Q R E + Q+ R+Q + K E QE+ + +++ Q
Sbjct: 2385 LKLRVAEMSRA-----QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2439
Query: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYR----- 1846
+SD + E E ++ + QQ + + E++Q +QEQ L++ + Q
Sbjct: 2440 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2499
Query: 1847 ----AEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIK 1902
E+F QEK++ E+ L+Q+E K +Q RE + +RQQ++ ++ RQ
Sbjct: 2500 DSLLQRERFIEQEKAKLEQ--LFQDEVAKAQQLREEQ------QRQQQQMEQERQRLVAS 2551
Query: 1903 SQEGKGHGRLLEPGTHQFASVPVRSSPLYEYIQEQRSQ 1940
+E + E G + + L + Q++R Q
Sbjct: 2552 MEEARRRQHEAEEGVRR------KQEELQQLEQQRRQQ 2583
Score = 311 bits (798), Expect = 3e-84
Identities = 324/1270 (25%), Positives = 597/1270 (47%), Gaps = 197/1270 (15%)
Query: 98 EKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE- 156
+ +A+ + + LQ R QEE RR + ++ + +R Q+ +Q R+ +E E Q++
Sbjct: 1381 QAKAQAEREAKELQQRMQEEVVRR---EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKA 1437
Query: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERR-AEEEQLQSCKGHETEEFPDEEQLRRREL 215
+Q +R R R +EE+ R + + E +R E +LQ+ + EE +++ + E
Sbjct: 1438 RQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRA-RAEEAEAQKRQAQEEA 1496
Query: 216 LELRRKGREEKQQQRR---ERQDRVFQEEEEKEWRKRETVLRKE--------EEKLQEEE 264
LRR+ ++E Q++R+ E RV E E ++R +E E +L++ E
Sbjct: 1497 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1556
Query: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
+R R++Q E ++ EL+ +R ++ +L R Q + RE+ E R +Q
Sbjct: 1557 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1616
Query: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
Q E+ E E++L R Q + E R Q EE +Q+ + E E+++++ RE + R
Sbjct: 1617 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1676
Query: 385 ---REQQLRR----EQQLRREQQLRR---EQQLRREQQLRR----------EQQLRREQQ 424
EQ +R+ EQ+L +++QL +Q+L EQ+L R ++QL E+
Sbjct: 1677 GKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEEL 1736
Query: 425 LRREQEEERHEQKHEQ-ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD---- 479
R ++E QK ++ E +++ E E R EE R E+ KQ+L+ +
Sbjct: 1737 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1796
Query: 480 -------------QEEERRERWLKLEEEERREQQERR-----------------EQQLRR 509
EE +R+R L E+ R+ + R E ++
Sbjct: 1797 RELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL 1856
Query: 510 EQEERREQRLKRQEEEERLQQRLRSEQ--QLRREQEERREQLLKR-----EEEKRLEQER 562
+++E +RL+R E+E Q+R EQ Q + + EER QL K E +K L ++
Sbjct: 1857 KEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDT 1916
Query: 563 REQRLKREQE---------------------------ERRDQLLKREEER---------- 585
QR + E+E D L +E+
Sbjct: 1917 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1976
Query: 586 -RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
++R +RE EER+++ L EE E Q + + ++R + + E ++L + EQE RQ
Sbjct: 1977 AEEERRRREAEERVQKSLAAEE-EAARQRKAALEEVERLKAKVEEARRLRERAEQESARQ 2035
Query: 645 QQLRREQQERREQRLKR------EEEEERLEQRLKREH---EEERREQELAE---EEQEQ 692
QL +E ++R Q ++ +++E+ L+Q L++E ++ R E E A EE E+
Sbjct: 2036 LQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2095
Query: 693 ARERIKSRIPKWQWQLESEADARQS---KVYSRPRKQ---EGQRRRQEQEEKRRRRESEL 746
AR + + + + Q+E +QS + +R + Q E R+ EQE RR + +
Sbjct: 2096 ARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQA 2155
Query: 747 QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA-----RPPLREQRERQLRAE 801
++++ A + ++ ++ + T + +A+ + E RL + L ++ ++L+AE
Sbjct: 2156 ALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2215
Query: 802 ERQQREQRFLPEEE--------EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
+ QR EEE E+ + + R E E L +++ QR LQEE
Sbjct: 2216 ATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR-----FLQEEA 2270
Query: 854 DGLQE--DQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEE 911
+ +++ ++ R S + + R EE+ ++R AL E++ KE+ +E
Sbjct: 2271 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQR-------ALAEKMLKEKMQAVQEAT 2323
Query: 912 ELQRE----EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967
L+ E +++K QEQ R+ +E++ +Q +QL E + +R E ERQ + + +
Sbjct: 2324 RLKAEAELLQQQKELAQEQARRLQEDK--EQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2381
Query: 968 QKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR----QEWERQYRKK 1023
+ +L E + + + E R ++ ++ E+L R E + + Q E Q ++
Sbjct: 2382 AERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2441
Query: 1024 D-ELQQEEEQLLREEREKRRLQERER--QYREEEELQQEEEQLLGEERETRRR--QELER 1078
D + ++ E + EREK +LQ+ + Q + EE ++EQLL E + ++ E +
Sbjct: 2442 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDS 2501
Query: 1079 QYRKEEELQQEE---EQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135
++E ++QE+ EQL ++E K +Q RE Q R++++++QE ++L+ E RR
Sbjct: 2502 LLQRERFIEQEKAKLEQLFQDEVAK-AQQLREEQQRQQQQMEQERQRLVASMEEARR--- 2557
Query: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
RQ+ EE V++++E+L Q+LE+Q R++EEL EE Q LRE+ + ++
Sbjct: 2558 --RQHEAEEGVRRKQEEL----------QQLEQQRRQQEELLAEENQRLREQLQLLEEQH 2605
Query: 1196 ERQYREEEEL 1205
EE+
Sbjct: 2606 RAALAHSEEV 2615
Score = 212 bits (539), Expect = 3e-54
Identities = 221/808 (27%), Positives = 387/808 (47%), Gaps = 87/808 (10%)
Query: 88 ALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRR--QKRQEQE 145
A+G+AT L E KE+ + R+ + F+ R+LEE+ Q + ++R Q
Sbjct: 1841 AIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQ--RRRLEEQAAQHKADIEERLAQL 1898
Query: 146 RELAEGEEQSEKQERLEQRDRQRR--DEELWRQRQEWQEREERRAE-EEQLQSCKGHETE 202
R+ ++ E + +K +E RQRR +EE+ + +++ +AE E +L + +
Sbjct: 1899 RKASDSELERQK-GLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA-- 1955
Query: 203 EFPDEEQLRRRELLEL----RRKGREEKQQQRRERQDRVFQE--EEEKEWRKRETVLRKE 256
E+ LR +E EL +R+ E++++RRE ++RV + EE+ R+R+ L +
Sbjct: 1956 ----EDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2011
Query: 257 EE-KLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL---RREQQLRRKQEE 312
E K + EE +R RE E+E + QE ++R + E++ ++EQ+L++ ++
Sbjct: 2012 ERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQ 2071
Query: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER 372
E+ + R E + R EE E R Q ER Q RR+ EE R +Q EQ + R
Sbjct: 2072 EQSVLDQLRGEAEAARRAAEEAEE---ARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2128
Query: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLR----------REQQLRREQQLRRE 422
+ Q E +LR+E + ++ + EQ R++Q EQ LR++ Q+ +E
Sbjct: 2129 AQAQAAAE-KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQE 2187
Query: 423 QQLRREQEEERHEQKHEQERREQRLKREQEE---RRDWLKREEETERHEQERRKQQLKRD 479
R Q EE QK+ + QRLK E E +R ++ E + R + E + R
Sbjct: 2188 LTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2247
Query: 480 QEEER------RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
+ E R ++ + +EE + ++ E+ R + RL++ EE+ QQR
Sbjct: 2248 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2307
Query: 534 SEQQLRREQEERRE--------QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585
+E+ L+ + + +E +LL++++E EQ RR Q E +E+ Q L E +
Sbjct: 2308 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ----EDKEQMAQQLAEETQG 2363
Query: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ 645
Q+ L+ E++ +LE + E ++ E R Q E+ + R+Q E E+ +
Sbjct: 2364 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ---AEEIGEKLHRT 2420
Query: 646 QLRREQQERREQRLK-REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKW 704
+L +++ Q L+ + ++ + +RL+ E RE+E ++E + + + +
Sbjct: 2421 ELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQ 2480
Query: 705 QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR 764
Q QL E A Q S + R EQE+ + Q ++E A QQ EEQ+
Sbjct: 2481 QEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE-----QLFQDEVAKAQQLREEQQ 2535
Query: 765 RDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQR 824
R +++ E+ RQRL A + E R RQ AEE +R+Q EE +Q +QR
Sbjct: 2536 RQ-------QQQMEQERQRLVA--SMEEARRRQHEAEEGVRRKQ------EELQQLEQQR 2580
Query: 825 REREKELQFLEEEEQLQRRERAQQLQEE 852
R++E+ L EE + RE+ Q L+E+
Sbjct: 2581 RQQEE----LLAEENQRLREQLQLLEEQ 2604
Score = 151 bits (382), Expect = 5e-36
Identities = 162/632 (25%), Positives = 294/632 (46%), Gaps = 80/632 (12%)
Query: 99 KRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQ-----------ERE 147
+RA + +E+ +Q R+ RR Q+EE +R +Q +EQ E+
Sbjct: 2087 RRAAEEAEEARVQAEREAAQSRR------QVEE--AERLKQSAEEQAQARAQAQAAAEKL 2138
Query: 148 LAEGEEQSEKQERLEQ---RDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
E E+++ ++ + EQ R +Q D E+ + ++ ++ ++A+ EQ + + EE
Sbjct: 2139 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2198
Query: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQD----RVFQEEEEK-----EWRKRETVLRK 255
++ L EL L+ + E +Q+ + ++ RV EE K E R +LR
Sbjct: 2199 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD 2258
Query: 256 EE--EKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ--EEEQQQQRLRREQQLRRK-- 309
++ ++ +EE ++ +++ EE +L + QE R RQ EE+ QQR E+ L+ K
Sbjct: 2259 KDNTQRFLQEEAEKMKQVAEEAARL-SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQ 2317
Query: 310 --QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE------EERRE 361
QE R + + E +QQ+ Q++ RR Q E +E+ QQL E + E R+
Sbjct: 2318 AVQEATRLKAEAELLQQQKELAQEQARRLQ----EDKEQMAQQLAEETQGFQRTLEAERQ 2373
Query: 362 QQLRREQEEER---REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
+QL E ER R ++ R Q E R +Q + +L ++++ Q
Sbjct: 2374 RQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT 2433
Query: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR 478
L ++Q E E E ER +++L Q+E + + EE + +QE+ Q+ +
Sbjct: 2434 LEIQRQQSDHDAERLREAIAELEREKEKL---QQEAKLLQLKSEEMQTVQQEQLLQETQA 2490
Query: 479 DQEEERRERWLKLEEEERREQQERREQQL-----RREQEERREQRLKRQEEEERLQQRLR 533
Q+ E+ L+ E EQ++ + +QL + Q+ R EQ+ ++Q+ E+ Q+ +
Sbjct: 2491 LQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVA 2550
Query: 534 SEQQLRREQEERREQLLKREEE-KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592
S ++ RR Q E E + +++EE ++LEQ+RR+Q ++LL E +R +++L+
Sbjct: 2551 SMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ----------EELLAEENQRLREQLQL 2600
Query: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRRE-- 650
+E+ EEV + + R+ + +E + E LRR+
Sbjct: 2601 LEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGP------AAEAEPEHSFDGLRRKVS 2654
Query: 651 QQERREQRLKREEEEERLEQRLKREHEEERRE 682
Q +E + EE +RL Q E RRE
Sbjct: 2655 AQRLQEAGILSAEELQRLAQGHTTVDELARRE 2686
Score = 96.3 bits (238), Expect = 3e-19
Identities = 86/335 (25%), Positives = 166/335 (49%), Gaps = 42/335 (12%)
Query: 80 KVAQACYYALGQATGLDEEKRARCDGKESLLQDRR------QEEDQRRFEPRDRQLEEEP 133
K+ Q A + E R R +E L Q R +E+ Q E + E E
Sbjct: 2272 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAEL 2331
Query: 134 GQRRRQKRQEQERELAEGEEQSEKQ--------ERLEQRDRQRRDE-----ELWRQRQEW 180
Q++++ QEQ R L E +EQ +Q +R + +RQR+ E E + R
Sbjct: 2332 LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAE 2391
Query: 181 QEREERRAEEEQLQSCKGHET-------EEFPDEEQLRRRELLELRRKGREEKQQQRRE- 232
R + RAEE+ + K E E +E++ + LE++R+ + ++ RE
Sbjct: 2392 MSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREA 2451
Query: 233 ------RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRK---LER 283
++++ QE + + + E ++E+ LQE + +Q L E++ L++ +E+
Sbjct: 2452 IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQ 2511
Query: 284 QELRRER--QEEEQQQQRLRREQQLRRKQEEERREQ----QEERREQQERREQQEERREQ 337
++ + E+ Q+E + Q+LR EQQ +++Q E+ R++ EE R +Q E+ R+++
Sbjct: 2512 EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQE 2571
Query: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEER 372
+L++ +++RR+Q+ +E +R +QL+ +E+ R
Sbjct: 2572 ELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHR 2606
Score = 37.4 bits (85), Expect = 0.14
Identities = 73/313 (23%), Positives = 122/313 (38%), Gaps = 57/313 (18%)
Query: 933 EEQLQQEEEQLLREEREKRRRQER----ERQYRKDKKLQQKEEQLL--GEEPEKRRRQER 986
E+QL+ E E+L +R + Q E Q + L Q + +LL G+ P++ ER
Sbjct: 381 EKQLRSEFERLECLQRIVTKLQMEAGLCEEQLNQADALLQSDVRLLAAGKVPQRAGEVER 440
Query: 987 E-KKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ-EEEQLLR--------- 1035
+ K L + Q L++ R + Q + R YR + L E LR
Sbjct: 441 DLDKADSMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPA 500
Query: 1036 EEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE----------LERQYRKEEE 1085
+ + LQ +R+ E+ + + LL E + R + +E Q
Sbjct: 501 TQVAQVTLQSVQRRPELEDSTLRYLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRG 560
Query: 1086 LQQEEEQLLREEPEKRRRQERE---------RQCREEEELQQEEEQLLREEREKRRRQEL 1136
L Q E+ R + E+ R E + R C +LQ + LL + + R E
Sbjct: 561 LHQSIEEF-RAKIERARSDEGQLSPATRGAYRDCLGRLDLQYAK--LLNSSKARLRSLES 617
Query: 1137 ERQY-------------REEEEV-----QQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178
+ +EEEEV + ++E +ELE + ++ +ELQ
Sbjct: 618 LHSFVAAATKELMWLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQN 677
Query: 1179 EEEQLLREEQEKR 1191
++LLRE+ R
Sbjct: 678 AGDRLLREDHPAR 690
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 342 bits (876), Expect = 3e-93
Identities = 446/1785 (24%), Positives = 774/1785 (43%), Gaps = 216/1785 (12%)
Query: 114 RQEEDQRRFEPRDRQL-EEEPG----------QRRRQKRQEQER------ELAEGEEQSE 156
R +D F P DR + E E G Q Q QE+ R EL + Q E
Sbjct: 942 RDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGAQEESRCQRCISELKDIRLQLE 1001
Query: 157 KQE-RLEQRDRQRRDEELWRQ-RQEWQEREERRAEEEQL------QSCKGHETEEFPDEE 208
E R R R D+E R+ Q E+++ +AE E L S + + P+
Sbjct: 1002 ACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPS 1061
Query: 209 QL--RRRELLELRRKGREEKQQQRRERQDRVFQEEEE------KEWRKRETVLRKEEEKL 260
R LEL E+ + ++ E+ + + + E VLR EE+L
Sbjct: 1062 PAAPTLRSELELTLGKLEQVRS-----LSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQL 1116
Query: 261 QEEE--PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318
+E + P EL+ + L+KL R + ++ + + LR Q++ + ++ E+
Sbjct: 1117 KEAQAVPATLPELEATKASLKKL-RAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERD 1175
Query: 319 EERREQQERREQQEERREQQLRREQEERRE-QQLRREQEEERRE-QQLRREQEEERREQQ 376
E +ER Q ER + L + +RE +QL R+ R L ++ RR Q+
Sbjct: 1176 VEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQE 1235
Query: 377 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE---- 432
+ L Q +R +QLR+EQ L E + R + E Q +Q + ++ E
Sbjct: 1236 QIQAMPLADSQAVR--EQLRQEQALLEE--IERHGEKVEECQRFAKQYINAIKDYELQLV 1291
Query: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR----------KQQLKRDQEE 482
++ + E + + Q ++ + H E + L+R +EE
Sbjct: 1292 TYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEE 1351
Query: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
ER + EE ER + E ++ R+ E + + + + E + LQQR++ E+ +RRE+
Sbjct: 1352 ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ-EEVVRREE 1410
Query: 543 EERREQLLKREEEKRLEQERRE-----QRLKREQEERRDQLLKREEERRQQRLKREQEER 597
Q KR ++ L+Q R+ Q R+ E L+ EEE R RL+ E ER
Sbjct: 1411 AAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATER 1470
Query: 598 -----------LEQRLKREEVERLEQEERREQRLKREEPEEERRQQ----LLKSEEQEER 642
L R + E ++ + +E E+ ++ + E +R++Q L + E
Sbjct: 1471 QRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAE 1530
Query: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIP 702
++ +R Q E RL+ EE E RL Q E E R+ Q E Q A ++S+
Sbjct: 1531 AAREKQRALQALEELRLQAEEAERRLRQ---AEVERARQVQVALETAQRSAEAELQSKRA 1587
Query: 703 KW-QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES---ELQ-WQ---EEERA 754
+ + + E ++ V ++E +RR Q+Q E R RE EL+ WQ E
Sbjct: 1588 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1647
Query: 755 HRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE- 813
R Q EE ++ Q +AE++ E + R EQ RQ E++ +QR L E
Sbjct: 1648 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEG 1707
Query: 814 --------EEEKEQRRRQRREREKELQFLEEE-EQLQRR-----ERAQQLQEEEDGLQED 859
E+E + R + + E++ Q LEEE +LQR ++ Q+L+ E ++ +
Sbjct: 1708 TAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAE 1767
Query: 860 QE-----RRRSQEQRR--DQKWRWQLEEERKRRRHTLYAKP---ALQEQLRKEQQLLQEE 909
E + R++E+ R +K + +LE E R R AL E+ ++++Q L EE
Sbjct: 1768 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQ-LAEE 1826
Query: 910 EEELQREEREK-------------RRRQEQERQYREEEQLQQEEEQLLREEREKRRR--- 953
+ QR E E+ R + E E +E+E + +L +E +RRR
Sbjct: 1827 DAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEE 1886
Query: 954 ---------QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
+ER Q RK + + ++ L E+ ++RRQ E+ + ++
Sbjct: 1887 QAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKA 1946
Query: 1005 REEREKRR-RQEWERQYRKKD--ELQQEEEQLLREEREKRRLQERERQYR----EEEELQ 1057
E E R R E R K+ EL+ ++ L E E+RR + ER + EEE +
Sbjct: 1947 ELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR 2006
Query: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117
Q + L ER + +E R + E+ + QL +E +KR + E + ++ +
Sbjct: 2007 QRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 2066
Query: 1118 QEEEQLLREERE--KRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175
QE +Q L++E+ + R E E R EE ++ Q RE + R RQ E E
Sbjct: 2067 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR------RQVEEAER 2120
Query: 1176 LQQE-EEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234
L+Q EEQ Q + E+ R+ E+E +R + +Q + Q +D E EK
Sbjct: 2121 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADA----EMEKHKK 2176
Query: 1235 VRDNKVYCKGRENEQFR----QLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRD 1290
+ + K + ++ QLE++ + ++LQ L E E R++ + +
Sbjct: 2177 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2236
Query: 1291 RHFPEEEQLEREEQKEAKRRD---RKSQEEKQLLREEREEKRRRQETDRKF----REEEQ 1343
EE + + + EA+ R R ++ L+EE E+ ++ E + +E +
Sbjct: 2237 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2296
Query: 1344 LLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQE 1403
L Q EE +++ K +E+++ ++ + E + L++Q K L +EQ R QE
Sbjct: 2297 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQ----KELAQEQARRLQE 2352
Query: 1404 REQQLRQDRDRKF----------REEEQQLSRQERDRKFREEEQ---QVRRQERERKFLE 1450
++Q+ Q + R+ + ++S + K R E Q R +E ++F +
Sbjct: 2353 DKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRK 2412
Query: 1451 EEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE--- 1507
+ +++ ++ HR ++ + + ++ RQ+ D + + ER+++ +QE
Sbjct: 2413 QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKL 2472
Query: 1508 LRSQEPERKFLEEEQQLHRQQR-QRKFLQEEQQLRRQERG-QQRRQDRDRKFREE----E 1561
L+ + E + +++EQ L Q Q+ FL E+ L ++ER +Q + ++ F++E +
Sbjct: 2473 LQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQ 2532
Query: 1562 QLRQERE-EQQLSRQERDRKFRLEEQKVRRQ----EQERKFMEDEQQLRRQEGQQ-QLRQ 1615
QLR+E++ +QQ QER R E+ RRQ E R+ E+ QQL +Q QQ +L
Sbjct: 2533 QLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLA 2592
Query: 1616 ERDRKFREDEQLLQEREEQQLHRQER--------DRKFLEEEPQLRRQEREQQLRHDRDR 1667
E +++ RE QLL+E+ L E + L E + H D
Sbjct: 2593 EENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDG 2652
Query: 1668 KFRE-EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ 1711
R+ Q LQE +R + +L R+E R +LQ
Sbjct: 2653 LRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQ 2697
Score = 326 bits (836), Expect = 1e-88
Identities = 360/1355 (26%), Positives = 617/1355 (45%), Gaps = 193/1355 (14%)
Query: 113 RRQEEDQR-----RFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQ 167
RR EE++R R E R+R E E E++R+LAE Q++ Q E ++ Q
Sbjct: 1346 RRMEEEERLAEQQRAEERERLAEVEAA-------LEKQRQLAEAHAQAKAQAEREAKELQ 1398
Query: 168 RR--DEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE- 224
+R +E + R+ ++++R+ +E+LQ QLR+ E++ K R+
Sbjct: 1399 QRMQEEVVRREEAAVDAQQQKRSIQEELQ--------------QLRQSSEAEIQAKARQA 1444
Query: 225 ---EKQQQRRERQDRVFQEEEEKEWRKR---ETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
E+ + R E + RV + + E R+R E L+ + +E E Q+ R+ QEE E+L
Sbjct: 1445 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK-RQAQEEAERL 1503
Query: 279 RKLERQELRRERQEEEQQQQRLRREQQLRRKQE------EERREQQEERREQQERREQQE 332
R+ + E +R+RQ E + R++ E + R+++ EE R Q EE E++ R+ + E
Sbjct: 1504 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE-AERRLRQAEVE 1562
Query: 333 ERREQQLRREQEER---REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
R+ Q+ E +R E Q +R E+ Q R QEE QLR E + R +QQ
Sbjct: 1563 RARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQA 1622
Query: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
E+ ++ QL+ + LR Q Q + + E +QK E ER +R +
Sbjct: 1623 EAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGK 1682
Query: 450 EQEE---RRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506
+E+ +R+ ++E E +R E QQ ++E R L+ E E+ +Q++ E++
Sbjct: 1683 AEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR---LRAETEQGEQQRQLLEEE 1739
Query: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566
L R Q E KRQE E L ++R E E + EEE R E+ +QR
Sbjct: 1740 LARLQREAAAATQKRQELEAEL-------AKVRAEMEVLLASKARAEEESRSTSEKSKQR 1792
Query: 567 LKRE------------------QEERRDQLLKREEERRQQ------------------RL 590
L+ E +E +R + L E+ RQ+ RL
Sbjct: 1793 LEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRL 1852
Query: 591 KREQEERL-EQRLKREEVERLEQEERREQRLKREEPE------EERRQQLLKSEEQEERR 643
K E E L E+ + E + RL ++E ++R E+ EER QL K+ + E R
Sbjct: 1853 KTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELER 1912
Query: 644 QQQL------RREQQERREQRLK--------------------REEEEERLEQRLKREHE 677
Q+ L +R Q E LK R E+ L + + E E
Sbjct: 1913 QKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELE 1972
Query: 678 EERREQELAEEE--QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQ 735
R+ Q AEEE + +A ER++ + + + + A +V K E RR +E+
Sbjct: 1973 AARQRQLAAEEERRRREAEERVQKSLAA-EEEAARQRKAALEEVERLKAKVEEARRLRER 2031
Query: 736 EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRE 795
E+ R+ +L +E A ++ Q EE+ F Q + +E + +Q S LR + E
Sbjct: 2032 AEQESARQLQL---AQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2088
Query: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDG 855
RA E + E+ + E E Q RRQ E E+ Q EEQ Q R +AQ E+
Sbjct: 2089 AARRAAE--EAEEARVQAEREAAQSRRQVEEAERLKQ--SAEEQAQARAQAQAAAEKLRK 2144
Query: 856 LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL----LQEEEE 911
E + RR+Q ++ + + + E + +H +A+ L+++ + EQ+L LQ EE
Sbjct: 2145 EAEQEAARRAQAEQAALRQKQAADAEME--KHKKFAEQTLRQKAQVEQELTTLRLQLEET 2202
Query: 912 ELQR---EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
+ Q+ +E +R + E R+ Q+++E + + E + + R + L+
Sbjct: 2203 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD 2262
Query: 969 KE--EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
K+ ++ L EE EK ++ E + + L EE ++R E+ ++K +
Sbjct: 2263 KDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQA 2322
Query: 1027 QQEEEQLLRE----EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK 1082
QE +L E +++K QE+ R+ +E++E Q +QL E + +R E ERQ +
Sbjct: 2323 VQEATRLKAEAELLQQQKELAQEQARRLQEDKE--QMAQQLAEETQGFQRTLEAERQ--R 2378
Query: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYRE 1142
+ E+ E E+L E R Q R EE+ Q+ +Q E EK R EL Q +
Sbjct: 2379 QLEMSAEAERLKLRVAEMSR-----AQARAEEDAQRFRKQ-AEEIGEKLHRTELATQEKV 2432
Query: 1143 EEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREE 1202
E ++ + +R R+ + RE+E+LQQE + L + +E + ++E+ +E
Sbjct: 2433 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQET 2492
Query: 1203 EELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQ 1262
+ LQ Q + E + S L+ + E+E A + + + +Q R E+ Q + +Q
Sbjct: 2493 QALQ-----QSFLSE-KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR--EEQQRQQQQ 2544
Query: 1263 SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR 1322
+Q+ Q L+ +E R Q E E+ R +Q+E ++ +++ +++++LL
Sbjct: 2545 MEQERQRLVASMEEARRRQH------------EAEEGVRRKQEELQQLEQQRRQQEELLA 2592
Query: 1323 EEREEKRRRQETDRKFREEEQLLQEREEQPLRRQE 1357
EE +++ RE+ QLL+E+ L E
Sbjct: 2593 EE----------NQRLREQLQLLEEQHRAALAHSE 2617
Score = 324 bits (830), Expect = 6e-88
Identities = 461/1845 (24%), Positives = 811/1845 (43%), Gaps = 259/1845 (14%)
Query: 253 LRKEEEK--LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQ 310
L+ EE++ L E Q L++ ++ L ER+ + Q L +
Sbjct: 921 LKPEEQRQALHSLELHYQAFLRDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGA 980
Query: 311 EEERREQQ--EERREQQERREQQEERREQQLR--------REQEERREQQLRREQEEERR 360
+EE R Q+ E ++ + + E E R +LR RE +R +Q + + E E
Sbjct: 981 QEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGL 1040
Query: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
+ + R E E+ L + LR E +L L + +Q+R + E+
Sbjct: 1041 GKGVARLSAEA--EKVLALPEPSPAAPTLRSELELT----LGKLEQVRSLSAIYLEKLKT 1094
Query: 421 REQQLRREQEEERHEQKHEQERREQRLKR----EQEERRDWLKR---EEETERHEQERRK 473
+R Q E + HE++ +E + E E + LK+ + E ++ + +
Sbjct: 1095 ISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALR 1154
Query: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
+L+ QE R + E + E+ R QL + Q RQ E E+L ++LR
Sbjct: 1155 DELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLR 1214
Query: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE 593
+ E + L ++ R QE+ + + + R+QL R+E+ + ++R
Sbjct: 1215 YYR-------ESADPLGAWLQDARRRQEQIQAMPLADSQAVREQL--RQEQALLEEIERH 1265
Query: 594 QEERLE-QRLKREEVERLEQEERREQRLKRE-EP--EEERRQQLLKSEEQEERRQQQLRR 649
E+ E QR ++ + ++ E + K + EP ++ ++ E + LR
Sbjct: 1266 GEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRT 1325
Query: 650 EQQERR----------EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
E + L+R EEEERL ++ + E E E E A E+Q Q
Sbjct: 1326 HYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQL------ 1379
Query: 700 RIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQ- 758
+EA A+ R K+ QR QEE RR E+ + Q+++R+ +++
Sbjct: 1380 ----------AEAHAQAKAQAEREAKELQQRM---QEEVVRREEAAVDAQQQKRSIQEEL 1426
Query: 759 QEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQ-----REQRFLPE 813
Q+ Q + Q +A + R RL +R R QL A ERQ+ Q
Sbjct: 1427 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVR-LQLEATERQRGGAEGELQALRAR 1485
Query: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRR----ERAQQLQEEEDGLQEDQERRRSQEQR 869
EE E ++RQ +E + L+ ++E ++R E A +++ E + +E Q ++ E+
Sbjct: 1486 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1545
Query: 870 RDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQ 929
R Q EE +R R A E+ R+ Q L+ + + E + KR E+
Sbjct: 1546 R-----LQAEEAERRLRQ------AEVERARQVQVALETAQRSAEAELQSKRA-SFAEKT 1593
Query: 930 YREEEQLQQEEEQL--LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE 987
+ E LQ+E + LREE E+R +Q+ E + +++ ++ E L R R + E
Sbjct: 1594 AQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE 1653
Query: 988 KKYREEEELQQEEEQLLRE-EREKRRRQEWERQYRKKDELQQEE------------EQLL 1034
+ +++ Q E E+ E ERE RRR + E Q ++ EL ++E +Q L
Sbjct: 1654 EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRL 1713
Query: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERE--TRRRQELERQYRKEEELQQEEEQ 1092
E+E RL+ Q ++ +L +EE L E T++RQELE + K ++ E E
Sbjct: 1714 AAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK---VRAEMEV 1770
Query: 1093 LL----REEPEKRRRQERERQCREEE-----ELQQEEEQL--LREEREKRRR---QELER 1138
LL R E E R E+ +Q E E EL +E +L L EE +++R+ ++ R
Sbjct: 1771 LLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAAR 1830
Query: 1139 QYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE--QEKRRQERE 1196
Q E E V E+ + E R + E E +E+E + +L +E Q +R +E+
Sbjct: 1831 QRAEAERVLAEKLAAIGEAT--RLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQA 1888
Query: 1197 RQYREE-EELQRQKRK----QRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFR 1251
Q++ + EE Q RK + R + D Q +E + + K +
Sbjct: 1889 AQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAEL 1948
Query: 1252 QLEDSQLRDR-----QSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE 1306
+LE ++R +S++ + Q++ E+ERRR + +R ++ L EE E
Sbjct: 1949 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER---VQKSLAAEE--E 2003
Query: 1307 AKRRDRKSQEEKQLLREEREEKRR-RQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365
A R+ + + EE + L+ + EE RR R+ +++ + QL QE ++ L+ +E+ F +
Sbjct: 2004 AARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ 2063
Query: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425
+ + Q + L++EQ + Q R + E R E ++ R +R+ + +Q+
Sbjct: 2064 QKEQELQ--QTLQQEQSVLDQLRG----EAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2117
Query: 1426 QERDRKFREEEQQVR--------------RQERERKFLEEEQQLRQ--------ERHRKF 1463
ER ++ EE+ Q R QE R+ E+ LRQ E+H+KF
Sbjct: 2118 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2177
Query: 1464 REEEQLLQEREEQ-------QLHRQERDRKFLEEEQQLRRQE-----RDRKFREQELRSQ 1511
E+ + + EQ QL + + L+EE Q + E R R E+EL S
Sbjct: 2178 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2237
Query: 1512 EPERKFLEEEQQLHRQQRQRKFLQEEQQLRR--QERGQQRRQDRDRKFR------EEEQL 1563
+ + L + + + + L+++ +R QE ++ +Q + R E +L
Sbjct: 2238 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2297
Query: 1564 RQEREE---QQLSRQERDRKFR----------------LEEQKVRRQEQERKFMEDEQQL 1604
RQ EE QQ + E+ K + L++QK QEQ R+ ED++Q+
Sbjct: 2298 RQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQM 2357
Query: 1605 RRQEGQQQLRQERDRKFREDEQLLQEREEQQLH----RQERDRKFLEEEPQLRRQEREQ- 1659
+Q ++ +R + QL E ++L R + EE+ Q R++ E+
Sbjct: 2358 AQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2417
Query: 1660 -QLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQ---Q 1715
+ H + +E+ L+Q E ++RQ+ D + + ERE++ LQ+E Q
Sbjct: 2418 GEKLHRTELATQEKVTLVQTLE---IQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2474
Query: 1716 LRRQELERKFREEEQLRQET---------EQEQLRRQERYRKILEEEQLRPE---REEQQ 1763
L+ +E++ ++EQL QET E++ L ++ER+ +E+E+ + E ++E
Sbjct: 2475 LKSEEMQTV--QQEQLLQETQALQQSFLSEKDSLLQRERF---IEQEKAKLEQLFQDEVA 2529
Query: 1764 LRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE-EEQLRQEREE-QQLRPQQRDGKY 1821
+Q R+ + R+++Q+ QER+ +E+ R+ E EE +R+++EE QQL Q+R +
Sbjct: 2530 KAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEE 2589
Query: 1822 RWEEEQLQLEEQEQRL-RQERDRQYRAEEQFATQEKSRR-------------EEQELWQE 1867
EE +L EQ Q L Q R +EE A+Q + + E E
Sbjct: 2590 LLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHS 2649
Query: 1868 EEQKRRQERERKLREEHI---RRQQKEEQRHRQVGEIKSQEGKGH 1909
+ RR+ ++L+E I Q+ Q H V E+ +E H
Sbjct: 2650 FDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRH 2694
Score = 321 bits (822), Expect = 5e-87
Identities = 452/1778 (25%), Positives = 777/1778 (43%), Gaps = 303/1778 (17%)
Query: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ--LRREQQL-----------RR 421
Q LRR+ QL R L + L+ E+Q + L Q LR Q R
Sbjct: 901 QSLRRDVQLIRSWSLATFRTLKPEEQRQALHSLELHYQAFLRDSQDAGGFGPEDRLMAER 960
Query: 422 E------------QQLRREQEEERHEQKHEQERREQRLKREQEERRDW----LKREEETE 465
E Q L + +EE Q+ E ++ RL+ E E R L ++E
Sbjct: 961 EYGSCSHHYQQLLQSLEQGAQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPA 1020
Query: 466 RHEQERRKQQLKRDQEEE-----------RRERWLKLEEEERREQQERREQQLRREQ-EE 513
R +R +Q K E E E+ L L E R E +L + E+
Sbjct: 1021 RECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQ 1080
Query: 514 RREQRLKRQEEEERLQQRLR----SEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
R E+ + + +R +E+ LR +E+ +E LE + + R
Sbjct: 1081 VRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLR 1140
Query: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER 629
Q E + + R + R +E ERL+QR +VE ER Q L ER
Sbjct: 1141 AQAEAQQPTF--DALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLL-------ER 1191
Query: 630 RQQLLKSEEQEERRQQQLRREQQERRE---------QRLKREEEE---------ERLEQR 671
Q +L + +R +QL R+ + RE Q +R +E+ + + ++
Sbjct: 1192 WQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQ 1251
Query: 672 LKREH---EEERREQELAEEEQEQARERIKS------RIPKWQWQLESEADARQSKVYSR 722
L++E EE R E EE Q A++ I + ++ ++ QLE A + +
Sbjct: 1252 LRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK-----K 1306
Query: 723 PRKQEGQRRRQEQEEKRRRRESEL----------------QWQEEERAHRQQQEEEQRRD 766
P+ Q G ++ R SEL + +EEER QQ+ EE+ R
Sbjct: 1307 PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER- 1365
Query: 767 FTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQR-EQRFLPEEEEKEQRRRQRR 825
+ E E+ RQ A + Q ER+ A+E QQR ++ + EE ++Q+R
Sbjct: 1366 ---LAEVEAALEKQRQLAEAHAQAKAQAERE--AKELQQRMQEEVVRREEAAVDAQQQKR 1420
Query: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR 885
++ELQ L + + + + +A+Q + E + R R +E+ R R QLE ++R
Sbjct: 1421 SIQEELQQLRQSSEAEIQAKARQAEAAE------RSRLRIEEEIRVV--RLQLEATERQR 1472
Query: 886 ---RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQER------------QY 930
L A A E+ +++ QEE E L+R+ +++ +R+ Q
Sbjct: 1473 GGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAA 1532
Query: 931 REEEQLQQ--EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK 988
RE+++ Q EE +L EE E+R RQ + R+ + + ++ E + +R EK
Sbjct: 1533 REKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEK 1592
Query: 989 KYREEEELQQEEEQL--LREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
+ E LQ+E + LREE E+R +Q+ E + R ++E ++E E+ + E RL+ +
Sbjct: 1593 TAQLERSLQEEHVAVAQLREEAERRAQQQAEAE-RAREEAERELERWQLKANEALRLRLQ 1651
Query: 1047 ERQYREEEELQQEEEQLLGEE--RETRRRQELERQYRKEEELQQEE----EQLLREEPEK 1100
+ +++ L Q E + EE RE RRR + E Q ++ EL ++E QL ++
Sbjct: 1652 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1711
Query: 1101 RRRQERER-QCREEEELQQEEEQLLREEREK---------RRRQELERQYREEEEVQQEE 1150
R E+E + R E E +++ QLL EE + ++RQELE E +V+ E
Sbjct: 1712 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA---ELAKVRAEM 1768
Query: 1151 EQLL----REEPEKRRRQELERQYREEE-----ELQQEEEQLLREEQEKRRQERERQYRE 1201
E LL R E E R E +Q E E EL +E +L +E +RQ RQ E
Sbjct: 1769 EVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ---RQLAE 1825
Query: 1202 EEELQRQKRKQRYRDEDQRS-DLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQL-- 1258
E+ +++ +R E + + + E E A+++ K ENE+ R+L + +
Sbjct: 1826 EDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKE-----KEAENERLRRLAEDEAFQ 1880
Query: 1259 RDRQSQQDLQH-------LLGEQQERDREQERRRWQQRD----RHFPEEEQLEREEQKEA 1307
R R +Q QH L ++ D E ER++ D R EEE L + E
Sbjct: 1881 RRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEK 1940
Query: 1308 KR-----------RDRKSQEEKQLLREEREEKRRRQ-----ETDRKFREEEQLLQEREEQ 1351
R R + E+ +E+ E + RQ E +R+ RE E ER ++
Sbjct: 1941 AAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE----ERVQK 1996
Query: 1352 PLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR-------------QERERKFLKEEQQ 1398
L +E + R+ L E+ + +EE +RLR QE +K L+ E++
Sbjct: 1997 SLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEK 2056
Query: 1399 LRC---QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ-ERE----RKFLE 1450
Q++EQ+L+Q ++ +Q E R+ EE ++ R Q ERE R+ +E
Sbjct: 2057 AHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2116
Query: 1451 EEQQLRQERHRKFREE-------EQLLQEREEQQLHRQERDRKFLEEEQQLRRQ-ERDRK 1502
E ++L+Q + + E+L +E E++ R + ++ L ++Q + E+ +K
Sbjct: 2117 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2176
Query: 1503 FREQELRSQ-EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561
F EQ LR + + E++ QL Q+ L EE Q + E + RQ R EEE
Sbjct: 2177 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQ---RSQVEEE 2233
Query: 1562 QLRQEREEQQLSRQERDRKFRLEEQK----VRRQEQERKFMEDEQQLRRQEGQQQLRQER 1617
+ ++LS+ K R+E + +R ++ ++F+++E + +Q ++ R
Sbjct: 2234 LFSVRVQMEELSKL----KARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV 2289
Query: 1618 DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQ 1677
+ E +L Q EE ++ K L+E+ Q ++ + + E +LLQ
Sbjct: 2290 AAQ--EAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT----------RLKAEAELLQ 2337
Query: 1678 EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ 1737
+ +E QE+ R+ +E+++Q+ +Q L EE Q ++ LE + + + ++ E E+
Sbjct: 2338 QQKELA---QEQARRLQEDKEQMAQQ------LAEETQGFQRTLEAERQRQLEMSAEAER 2388
Query: 1738 EQLRRQERYRKILEEEQLRPEREEQQLRRQERD--RKFREEEQLRQER----EEQQLRSQ 1791
+LR E R Q R E + Q+ R+Q + K E QE+ + +++ Q
Sbjct: 2389 LKLRVAEMSRA-----QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2443
Query: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYR----- 1846
+SD + E E ++ + QQ + + E++Q +QEQ L++ + Q
Sbjct: 2444 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2503
Query: 1847 ----AEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIK 1902
E+F QEK++ E+ L+Q+E K +Q RE + +RQQ++ ++ RQ
Sbjct: 2504 DSLLQRERFIEQEKAKLEQ--LFQDEVAKAQQLREEQ------QRQQQQMEQERQRLVAS 2555
Query: 1903 SQEGKGHGRLLEPGTHQFASVPVRSSPLYEYIQEQRSQ 1940
+E + E G + + L + Q++R Q
Sbjct: 2556 MEEARRRQHEAEEGVRR------KQEELQQLEQQRRQQ 2587
Score = 311 bits (798), Expect = 3e-84
Identities = 324/1270 (25%), Positives = 597/1270 (47%), Gaps = 197/1270 (15%)
Query: 98 EKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE- 156
+ +A+ + + LQ R QEE RR + ++ + +R Q+ +Q R+ +E E Q++
Sbjct: 1385 QAKAQAEREAKELQQRMQEEVVRR---EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKA 1441
Query: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERR-AEEEQLQSCKGHETEEFPDEEQLRRREL 215
+Q +R R R +EE+ R + + E +R E +LQ+ + EE +++ + E
Sbjct: 1442 RQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRA-RAEEAEAQKRQAQEEA 1500
Query: 216 LELRRKGREEKQQQRR---ERQDRVFQEEEEKEWRKRETVLRKE--------EEKLQEEE 264
LRR+ ++E Q++R+ E RV E E ++R +E E +L++ E
Sbjct: 1501 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1560
Query: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
+R R++Q E ++ EL+ +R ++ +L R Q + RE+ E R +Q
Sbjct: 1561 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1620
Query: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
Q E+ E E++L R Q + E R Q EE +Q+ + E E+++++ RE + R
Sbjct: 1621 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1680
Query: 385 ---REQQLRR----EQQLRREQQLRR---EQQLRREQQLRR----------EQQLRREQQ 424
EQ +R+ EQ+L +++QL +Q+L EQ+L R ++QL E+
Sbjct: 1681 GKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEEL 1740
Query: 425 LRREQEEERHEQKHEQ-ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD---- 479
R ++E QK ++ E +++ E E R EE R E+ KQ+L+ +
Sbjct: 1741 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1800
Query: 480 -------------QEEERRERWLKLEEEERREQQERR-----------------EQQLRR 509
EE +R+R L E+ R+ + R E ++
Sbjct: 1801 RELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL 1860
Query: 510 EQEERREQRLKRQEEEERLQQRLRSEQ--QLRREQEERREQLLKR-----EEEKRLEQER 562
+++E +RL+R E+E Q+R EQ Q + + EER QL K E +K L ++
Sbjct: 1861 KEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDT 1920
Query: 563 REQRLKREQE---------------------------ERRDQLLKREEER---------- 585
QR + E+E D L +E+
Sbjct: 1921 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1980
Query: 586 -RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
++R +RE EER+++ L EE E Q + + ++R + + E ++L + EQE RQ
Sbjct: 1981 AEEERRRREAEERVQKSLAAEE-EAARQRKAALEEVERLKAKVEEARRLRERAEQESARQ 2039
Query: 645 QQLRREQQERREQRLKR------EEEEERLEQRLKREH---EEERREQELAE---EEQEQ 692
QL +E ++R Q ++ +++E+ L+Q L++E ++ R E E A EE E+
Sbjct: 2040 LQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2099
Query: 693 ARERIKSRIPKWQWQLESEADARQS---KVYSRPRKQ---EGQRRRQEQEEKRRRRESEL 746
AR + + + + Q+E +QS + +R + Q E R+ EQE RR + +
Sbjct: 2100 ARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQA 2159
Query: 747 QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA-----RPPLREQRERQLRAE 801
++++ A + ++ ++ + T + +A+ + E RL + L ++ ++L+AE
Sbjct: 2160 ALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2219
Query: 802 ERQQREQRFLPEEE--------EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
+ QR EEE E+ + + R E E L +++ QR LQEE
Sbjct: 2220 ATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR-----FLQEEA 2274
Query: 854 DGLQE--DQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEE 911
+ +++ ++ R S + + R EE+ ++R AL E++ KE+ +E
Sbjct: 2275 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQR-------ALAEKMLKEKMQAVQEAT 2327
Query: 912 ELQRE----EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967
L+ E +++K QEQ R+ +E++ +Q +QL E + +R E ERQ + + +
Sbjct: 2328 RLKAEAELLQQQKELAQEQARRLQEDK--EQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2385
Query: 968 QKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR----QEWERQYRKK 1023
+ +L E + + + E R ++ ++ E+L R E + + Q E Q ++
Sbjct: 2386 AERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2445
Query: 1024 D-ELQQEEEQLLREEREKRRLQERER--QYREEEELQQEEEQLLGEERETRRR--QELER 1078
D + ++ E + EREK +LQ+ + Q + EE ++EQLL E + ++ E +
Sbjct: 2446 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDS 2505
Query: 1079 QYRKEEELQQEE---EQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135
++E ++QE+ EQL ++E K +Q RE Q R++++++QE ++L+ E RR
Sbjct: 2506 LLQRERFIEQEKAKLEQLFQDEVAK-AQQLREEQQRQQQQMEQERQRLVASMEEARR--- 2561
Query: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
RQ+ EE V++++E+L Q+LE+Q R++EEL EE Q LRE+ + ++
Sbjct: 2562 --RQHEAEEGVRRKQEEL----------QQLEQQRRQQEELLAEENQRLREQLQLLEEQH 2609
Query: 1196 ERQYREEEEL 1205
EE+
Sbjct: 2610 RAALAHSEEV 2619
Score = 212 bits (539), Expect = 3e-54
Identities = 221/808 (27%), Positives = 387/808 (47%), Gaps = 87/808 (10%)
Query: 88 ALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRR--QKRQEQE 145
A+G+AT L E KE+ + R+ + F+ R+LEE+ Q + ++R Q
Sbjct: 1845 AIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQ--RRRLEEQAAQHKADIEERLAQL 1902
Query: 146 RELAEGEEQSEKQERLEQRDRQRR--DEELWRQRQEWQEREERRAE-EEQLQSCKGHETE 202
R+ ++ E + +K +E RQRR +EE+ + +++ +AE E +L + +
Sbjct: 1903 RKASDSELERQK-GLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA-- 1959
Query: 203 EFPDEEQLRRRELLEL----RRKGREEKQQQRRERQDRVFQE--EEEKEWRKRETVLRKE 256
E+ LR +E EL +R+ E++++RRE ++RV + EE+ R+R+ L +
Sbjct: 1960 ----EDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2015
Query: 257 EE-KLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL---RREQQLRRKQEE 312
E K + EE +R RE E+E + QE ++R + E++ ++EQ+L++ ++
Sbjct: 2016 ERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQ 2075
Query: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER 372
E+ + R E + R EE E R Q ER Q RR+ EE R +Q EQ + R
Sbjct: 2076 EQSVLDQLRGEAEAARRAAEEAEE---ARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2132
Query: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLR----------REQQLRREQQLRRE 422
+ Q E +LR+E + ++ + EQ R++Q EQ LR++ Q+ +E
Sbjct: 2133 AQAQAAAE-KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQE 2191
Query: 423 QQLRREQEEERHEQKHEQERREQRLKREQEE---RRDWLKREEETERHEQERRKQQLKRD 479
R Q EE QK+ + QRLK E E +R ++ E + R + E + R
Sbjct: 2192 LTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2251
Query: 480 QEEER------RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
+ E R ++ + +EE + ++ E+ R + RL++ EE+ QQR
Sbjct: 2252 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2311
Query: 534 SEQQLRREQEERRE--------QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585
+E+ L+ + + +E +LL++++E EQ RR Q E +E+ Q L E +
Sbjct: 2312 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ----EDKEQMAQQLAEETQG 2367
Query: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ 645
Q+ L+ E++ +LE + E ++ E R Q E+ + R+Q E E+ +
Sbjct: 2368 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ---AEEIGEKLHRT 2424
Query: 646 QLRREQQERREQRLK-REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKW 704
+L +++ Q L+ + ++ + +RL+ E RE+E ++E + + + +
Sbjct: 2425 ELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQ 2484
Query: 705 QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR 764
Q QL E A Q S + R EQE+ + Q ++E A QQ EEQ+
Sbjct: 2485 QEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE-----QLFQDEVAKAQQLREEQQ 2539
Query: 765 RDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQR 824
R +++ E+ RQRL A + E R RQ AEE +R+Q EE +Q +QR
Sbjct: 2540 RQ-------QQQMEQERQRLVA--SMEEARRRQHEAEEGVRRKQ------EELQQLEQQR 2584
Query: 825 REREKELQFLEEEEQLQRRERAQQLQEE 852
R++E+ L EE + RE+ Q L+E+
Sbjct: 2585 RQQEE----LLAEENQRLREQLQLLEEQ 2608
Score = 151 bits (382), Expect = 5e-36
Identities = 162/632 (25%), Positives = 294/632 (46%), Gaps = 80/632 (12%)
Query: 99 KRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQ-----------ERE 147
+RA + +E+ +Q R+ RR Q+EE +R +Q +EQ E+
Sbjct: 2091 RRAAEEAEEARVQAEREAAQSRR------QVEE--AERLKQSAEEQAQARAQAQAAAEKL 2142
Query: 148 LAEGEEQSEKQERLEQ---RDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
E E+++ ++ + EQ R +Q D E+ + ++ ++ ++A+ EQ + + EE
Sbjct: 2143 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2202
Query: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQD----RVFQEEEEK-----EWRKRETVLRK 255
++ L EL L+ + E +Q+ + ++ RV EE K E R +LR
Sbjct: 2203 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD 2262
Query: 256 EE--EKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ--EEEQQQQRLRREQQLRRK-- 309
++ ++ +EE ++ +++ EE +L + QE R RQ EE+ QQR E+ L+ K
Sbjct: 2263 KDNTQRFLQEEAEKMKQVAEEAARL-SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQ 2321
Query: 310 --QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE------EERRE 361
QE R + + E +QQ+ Q++ RR Q E +E+ QQL E + E R+
Sbjct: 2322 AVQEATRLKAEAELLQQQKELAQEQARRLQ----EDKEQMAQQLAEETQGFQRTLEAERQ 2377
Query: 362 QQLRREQEEER---REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
+QL E ER R ++ R Q E R +Q + +L ++++ Q
Sbjct: 2378 RQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT 2437
Query: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR 478
L ++Q E E E ER +++L Q+E + + EE + +QE+ Q+ +
Sbjct: 2438 LEIQRQQSDHDAERLREAIAELEREKEKL---QQEAKLLQLKSEEMQTVQQEQLLQETQA 2494
Query: 479 DQEEERRERWLKLEEEERREQQERREQQL-----RREQEERREQRLKRQEEEERLQQRLR 533
Q+ E+ L+ E EQ++ + +QL + Q+ R EQ+ ++Q+ E+ Q+ +
Sbjct: 2495 LQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVA 2554
Query: 534 SEQQLRREQEERREQLLKREEE-KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592
S ++ RR Q E E + +++EE ++LEQ+RR+Q ++LL E +R +++L+
Sbjct: 2555 SMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ----------EELLAEENQRLREQLQL 2604
Query: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRRE-- 650
+E+ EEV + + R+ + +E + E LRR+
Sbjct: 2605 LEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGP------AAEAEPEHSFDGLRRKVS 2658
Query: 651 QQERREQRLKREEEEERLEQRLKREHEEERRE 682
Q +E + EE +RL Q E RRE
Sbjct: 2659 AQRLQEAGILSAEELQRLAQGHTTVDELARRE 2690
Score = 96.3 bits (238), Expect = 3e-19
Identities = 86/335 (25%), Positives = 166/335 (49%), Gaps = 42/335 (12%)
Query: 80 KVAQACYYALGQATGLDEEKRARCDGKESLLQDRR------QEEDQRRFEPRDRQLEEEP 133
K+ Q A + E R R +E L Q R +E+ Q E + E E
Sbjct: 2276 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAEL 2335
Query: 134 GQRRRQKRQEQERELAEGEEQSEKQ--------ERLEQRDRQRRDE-----ELWRQRQEW 180
Q++++ QEQ R L E +EQ +Q +R + +RQR+ E E + R
Sbjct: 2336 LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAE 2395
Query: 181 QEREERRAEEEQLQSCKGHET-------EEFPDEEQLRRRELLELRRKGREEKQQQRRE- 232
R + RAEE+ + K E E +E++ + LE++R+ + ++ RE
Sbjct: 2396 MSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREA 2455
Query: 233 ------RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRK---LER 283
++++ QE + + + E ++E+ LQE + +Q L E++ L++ +E+
Sbjct: 2456 IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQ 2515
Query: 284 QELRRER--QEEEQQQQRLRREQQLRRKQEEERREQ----QEERREQQERREQQEERREQ 337
++ + E+ Q+E + Q+LR EQQ +++Q E+ R++ EE R +Q E+ R+++
Sbjct: 2516 EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQE 2575
Query: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEER 372
+L++ +++RR+Q+ +E +R +QL+ +E+ R
Sbjct: 2576 ELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHR 2610
Score = 37.4 bits (85), Expect = 0.14
Identities = 73/313 (23%), Positives = 122/313 (38%), Gaps = 57/313 (18%)
Query: 933 EEQLQQEEEQLLREEREKRRRQER----ERQYRKDKKLQQKEEQLL--GEEPEKRRRQER 986
E+QL+ E E+L +R + Q E Q + L Q + +LL G+ P++ ER
Sbjct: 385 EKQLRSEFERLECLQRIVTKLQMEAGLCEEQLNQADALLQSDVRLLAAGKVPQRAGEVER 444
Query: 987 E-KKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ-EEEQLLR--------- 1035
+ K L + Q L++ R + Q + R YR + L E LR
Sbjct: 445 DLDKADSMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPA 504
Query: 1036 EEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE----------LERQYRKEEE 1085
+ + LQ +R+ E+ + + LL E + R + +E Q
Sbjct: 505 TQVAQVTLQSVQRRPELEDSTLRYLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRG 564
Query: 1086 LQQEEEQLLREEPEKRRRQERE---------RQCREEEELQQEEEQLLREEREKRRRQEL 1136
L Q E+ R + E+ R E + R C +LQ + LL + + R E
Sbjct: 565 LHQSIEEF-RAKIERARSDEGQLSPATRGAYRDCLGRLDLQYAK--LLNSSKARLRSLES 621
Query: 1137 ERQY-------------REEEEV-----QQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178
+ +EEEEV + ++E +ELE + ++ +ELQ
Sbjct: 622 LHSFVAAATKELMWLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQN 681
Query: 1179 EEEQLLREEQEKR 1191
++LLRE+ R
Sbjct: 682 AGDRLLREDHPAR 694
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 342 bits (876), Expect = 3e-93
Identities = 446/1785 (24%), Positives = 774/1785 (43%), Gaps = 216/1785 (12%)
Query: 114 RQEEDQRRFEPRDRQL-EEEPG----------QRRRQKRQEQER------ELAEGEEQSE 156
R +D F P DR + E E G Q Q QE+ R EL + Q E
Sbjct: 938 RDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGAQEESRCQRCISELKDIRLQLE 997
Query: 157 KQE-RLEQRDRQRRDEELWRQ-RQEWQEREERRAEEEQL------QSCKGHETEEFPDEE 208
E R R R D+E R+ Q E+++ +AE E L S + + P+
Sbjct: 998 ACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPS 1057
Query: 209 QL--RRRELLELRRKGREEKQQQRRERQDRVFQEEEE------KEWRKRETVLRKEEEKL 260
R LEL E+ + ++ E+ + + + E VLR EE+L
Sbjct: 1058 PAAPTLRSELELTLGKLEQVRS-----LSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQL 1112
Query: 261 QEEE--PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318
+E + P EL+ + L+KL R + ++ + + LR Q++ + ++ E+
Sbjct: 1113 KEAQAVPATLPELEATKASLKKL-RAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERD 1171
Query: 319 EERREQQERREQQEERREQQLRREQEERRE-QQLRREQEEERRE-QQLRREQEEERREQQ 376
E +ER Q ER + L + +RE +QL R+ R L ++ RR Q+
Sbjct: 1172 VEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQE 1231
Query: 377 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE---- 432
+ L Q +R +QLR+EQ L E + R + E Q +Q + ++ E
Sbjct: 1232 QIQAMPLADSQAVR--EQLRQEQALLEE--IERHGEKVEECQRFAKQYINAIKDYELQLV 1287
Query: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR----------KQQLKRDQEE 482
++ + E + + Q ++ + H E + L+R +EE
Sbjct: 1288 TYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEE 1347
Query: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
ER + EE ER + E ++ R+ E + + + + E + LQQR++ E+ +RRE+
Sbjct: 1348 ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ-EEVVRREE 1406
Query: 543 EERREQLLKREEEKRLEQERRE-----QRLKREQEERRDQLLKREEERRQQRLKREQEER 597
Q KR ++ L+Q R+ Q R+ E L+ EEE R RL+ E ER
Sbjct: 1407 AAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATER 1466
Query: 598 -----------LEQRLKREEVERLEQEERREQRLKREEPEEERRQQ----LLKSEEQEER 642
L R + E ++ + +E E+ ++ + E +R++Q L + E
Sbjct: 1467 QRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAE 1526
Query: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIP 702
++ +R Q E RL+ EE E RL Q E E R+ Q E Q A ++S+
Sbjct: 1527 AAREKQRALQALEELRLQAEEAERRLRQ---AEVERARQVQVALETAQRSAEAELQSKRA 1583
Query: 703 KW-QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES---ELQ-WQ---EEERA 754
+ + + E ++ V ++E +RR Q+Q E R RE EL+ WQ E
Sbjct: 1584 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1643
Query: 755 HRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE- 813
R Q EE ++ Q +AE++ E + R EQ RQ E++ +QR L E
Sbjct: 1644 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEG 1703
Query: 814 --------EEEKEQRRRQRREREKELQFLEEE-EQLQRR-----ERAQQLQEEEDGLQED 859
E+E + R + + E++ Q LEEE +LQR ++ Q+L+ E ++ +
Sbjct: 1704 TAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAE 1763
Query: 860 QE-----RRRSQEQRR--DQKWRWQLEEERKRRRHTLYAKP---ALQEQLRKEQQLLQEE 909
E + R++E+ R +K + +LE E R R AL E+ ++++Q L EE
Sbjct: 1764 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQ-LAEE 1822
Query: 910 EEELQREEREK-------------RRRQEQERQYREEEQLQQEEEQLLREEREKRRR--- 953
+ QR E E+ R + E E +E+E + +L +E +RRR
Sbjct: 1823 DAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEE 1882
Query: 954 ---------QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
+ER Q RK + + ++ L E+ ++RRQ E+ + ++
Sbjct: 1883 QAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKA 1942
Query: 1005 REEREKRR-RQEWERQYRKKD--ELQQEEEQLLREEREKRRLQERERQYR----EEEELQ 1057
E E R R E R K+ EL+ ++ L E E+RR + ER + EEE +
Sbjct: 1943 ELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR 2002
Query: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117
Q + L ER + +E R + E+ + QL +E +KR + E + ++ +
Sbjct: 2003 QRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 2062
Query: 1118 QEEEQLLREERE--KRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175
QE +Q L++E+ + R E E R EE ++ Q RE + R RQ E E
Sbjct: 2063 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR------RQVEEAER 2116
Query: 1176 LQQE-EEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234
L+Q EEQ Q + E+ R+ E+E +R + +Q + Q +D E EK
Sbjct: 2117 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADA----EMEKHKK 2172
Query: 1235 VRDNKVYCKGRENEQFR----QLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRD 1290
+ + K + ++ QLE++ + ++LQ L E E R++ + +
Sbjct: 2173 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2232
Query: 1291 RHFPEEEQLEREEQKEAKRRD---RKSQEEKQLLREEREEKRRRQETDRKF----REEEQ 1343
EE + + + EA+ R R ++ L+EE E+ ++ E + +E +
Sbjct: 2233 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2292
Query: 1344 LLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQE 1403
L Q EE +++ K +E+++ ++ + E + L++Q K L +EQ R QE
Sbjct: 2293 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQ----KELAQEQARRLQE 2348
Query: 1404 REQQLRQDRDRKF----------REEEQQLSRQERDRKFREEEQ---QVRRQERERKFLE 1450
++Q+ Q + R+ + ++S + K R E Q R +E ++F +
Sbjct: 2349 DKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRK 2408
Query: 1451 EEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE--- 1507
+ +++ ++ HR ++ + + ++ RQ+ D + + ER+++ +QE
Sbjct: 2409 QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKL 2468
Query: 1508 LRSQEPERKFLEEEQQLHRQQR-QRKFLQEEQQLRRQERG-QQRRQDRDRKFREE----E 1561
L+ + E + +++EQ L Q Q+ FL E+ L ++ER +Q + ++ F++E +
Sbjct: 2469 LQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQ 2528
Query: 1562 QLRQERE-EQQLSRQERDRKFRLEEQKVRRQ----EQERKFMEDEQQLRRQEGQQ-QLRQ 1615
QLR+E++ +QQ QER R E+ RRQ E R+ E+ QQL +Q QQ +L
Sbjct: 2529 QLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLA 2588
Query: 1616 ERDRKFREDEQLLQEREEQQLHRQER--------DRKFLEEEPQLRRQEREQQLRHDRDR 1667
E +++ RE QLL+E+ L E + L E + H D
Sbjct: 2589 EENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDG 2648
Query: 1668 KFRE-EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ 1711
R+ Q LQE +R + +L R+E R +LQ
Sbjct: 2649 LRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQ 2693
Score = 326 bits (836), Expect = 1e-88
Identities = 360/1355 (26%), Positives = 617/1355 (45%), Gaps = 193/1355 (14%)
Query: 113 RRQEEDQR-----RFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQ 167
RR EE++R R E R+R E E E++R+LAE Q++ Q E ++ Q
Sbjct: 1342 RRMEEEERLAEQQRAEERERLAEVEAA-------LEKQRQLAEAHAQAKAQAEREAKELQ 1394
Query: 168 RR--DEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE- 224
+R +E + R+ ++++R+ +E+LQ QLR+ E++ K R+
Sbjct: 1395 QRMQEEVVRREEAAVDAQQQKRSIQEELQ--------------QLRQSSEAEIQAKARQA 1440
Query: 225 ---EKQQQRRERQDRVFQEEEEKEWRKR---ETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
E+ + R E + RV + + E R+R E L+ + +E E Q+ R+ QEE E+L
Sbjct: 1441 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK-RQAQEEAERL 1499
Query: 279 RKLERQELRRERQEEEQQQQRLRREQQLRRKQE------EERREQQEERREQQERREQQE 332
R+ + E +R+RQ E + R++ E + R+++ EE R Q EE E++ R+ + E
Sbjct: 1500 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE-AERRLRQAEVE 1558
Query: 333 ERREQQLRREQEER---REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
R+ Q+ E +R E Q +R E+ Q R QEE QLR E + R +QQ
Sbjct: 1559 RARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQA 1618
Query: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
E+ ++ QL+ + LR Q Q + + E +QK E ER +R +
Sbjct: 1619 EAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGK 1678
Query: 450 EQEE---RRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506
+E+ +R+ ++E E +R E QQ ++E R L+ E E+ +Q++ E++
Sbjct: 1679 AEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR---LRAETEQGEQQRQLLEEE 1735
Query: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566
L R Q E KRQE E L ++R E E + EEE R E+ +QR
Sbjct: 1736 LARLQREAAAATQKRQELEAEL-------AKVRAEMEVLLASKARAEEESRSTSEKSKQR 1788
Query: 567 LKRE------------------QEERRDQLLKREEERRQQ------------------RL 590
L+ E +E +R + L E+ RQ+ RL
Sbjct: 1789 LEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRL 1848
Query: 591 KREQEERL-EQRLKREEVERLEQEERREQRLKREEPE------EERRQQLLKSEEQEERR 643
K E E L E+ + E + RL ++E ++R E+ EER QL K+ + E R
Sbjct: 1849 KTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELER 1908
Query: 644 QQQL------RREQQERREQRLK--------------------REEEEERLEQRLKREHE 677
Q+ L +R Q E LK R E+ L + + E E
Sbjct: 1909 QKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELE 1968
Query: 678 EERREQELAEEE--QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQ 735
R+ Q AEEE + +A ER++ + + + + A +V K E RR +E+
Sbjct: 1969 AARQRQLAAEEERRRREAEERVQKSLAA-EEEAARQRKAALEEVERLKAKVEEARRLRER 2027
Query: 736 EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRE 795
E+ R+ +L +E A ++ Q EE+ F Q + +E + +Q S LR + E
Sbjct: 2028 AEQESARQLQL---AQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2084
Query: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDG 855
RA E + E+ + E E Q RRQ E E+ Q EEQ Q R +AQ E+
Sbjct: 2085 AARRAAE--EAEEARVQAEREAAQSRRQVEEAERLKQ--SAEEQAQARAQAQAAAEKLRK 2140
Query: 856 LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL----LQEEEE 911
E + RR+Q ++ + + + E + +H +A+ L+++ + EQ+L LQ EE
Sbjct: 2141 EAEQEAARRAQAEQAALRQKQAADAEME--KHKKFAEQTLRQKAQVEQELTTLRLQLEET 2198
Query: 912 ELQR---EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
+ Q+ +E +R + E R+ Q+++E + + E + + R + L+
Sbjct: 2199 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD 2258
Query: 969 KE--EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
K+ ++ L EE EK ++ E + + L EE ++R E+ ++K +
Sbjct: 2259 KDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQA 2318
Query: 1027 QQEEEQLLRE----EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK 1082
QE +L E +++K QE+ R+ +E++E Q +QL E + +R E ERQ +
Sbjct: 2319 VQEATRLKAEAELLQQQKELAQEQARRLQEDKE--QMAQQLAEETQGFQRTLEAERQ--R 2374
Query: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYRE 1142
+ E+ E E+L E R Q R EE+ Q+ +Q E EK R EL Q +
Sbjct: 2375 QLEMSAEAERLKLRVAEMSR-----AQARAEEDAQRFRKQ-AEEIGEKLHRTELATQEKV 2428
Query: 1143 EEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREE 1202
E ++ + +R R+ + RE+E+LQQE + L + +E + ++E+ +E
Sbjct: 2429 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQET 2488
Query: 1203 EELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQ 1262
+ LQ Q + E + S L+ + E+E A + + + +Q R E+ Q + +Q
Sbjct: 2489 QALQ-----QSFLSE-KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR--EEQQRQQQQ 2540
Query: 1263 SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR 1322
+Q+ Q L+ +E R Q E E+ R +Q+E ++ +++ +++++LL
Sbjct: 2541 MEQERQRLVASMEEARRRQH------------EAEEGVRRKQEELQQLEQQRRQQEELLA 2588
Query: 1323 EEREEKRRRQETDRKFREEEQLLQEREEQPLRRQE 1357
EE +++ RE+ QLL+E+ L E
Sbjct: 2589 EE----------NQRLREQLQLLEEQHRAALAHSE 2613
Score = 324 bits (830), Expect = 6e-88
Identities = 461/1845 (24%), Positives = 811/1845 (43%), Gaps = 259/1845 (14%)
Query: 253 LRKEEEK--LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQ 310
L+ EE++ L E Q L++ ++ L ER+ + Q L +
Sbjct: 917 LKPEEQRQALHSLELHYQAFLRDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGA 976
Query: 311 EEERREQQ--EERREQQERREQQEERREQQLR--------REQEERREQQLRREQEEERR 360
+EE R Q+ E ++ + + E E R +LR RE +R +Q + + E E
Sbjct: 977 QEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGL 1036
Query: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
+ + R E E+ L + LR E +L L + +Q+R + E+
Sbjct: 1037 GKGVARLSAEA--EKVLALPEPSPAAPTLRSELELT----LGKLEQVRSLSAIYLEKLKT 1090
Query: 421 REQQLRREQEEERHEQKHEQERREQRLKR----EQEERRDWLKR---EEETERHEQERRK 473
+R Q E + HE++ +E + E E + LK+ + E ++ + +
Sbjct: 1091 ISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALR 1150
Query: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
+L+ QE R + E + E+ R QL + Q RQ E E+L ++LR
Sbjct: 1151 DELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLR 1210
Query: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE 593
+ E + L ++ R QE+ + + + R+QL R+E+ + ++R
Sbjct: 1211 YYR-------ESADPLGAWLQDARRRQEQIQAMPLADSQAVREQL--RQEQALLEEIERH 1261
Query: 594 QEERLE-QRLKREEVERLEQEERREQRLKRE-EP--EEERRQQLLKSEEQEERRQQQLRR 649
E+ E QR ++ + ++ E + K + EP ++ ++ E + LR
Sbjct: 1262 GEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRT 1321
Query: 650 EQQERR----------EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
E + L+R EEEERL ++ + E E E E A E+Q Q
Sbjct: 1322 HYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQL------ 1375
Query: 700 RIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQ- 758
+EA A+ R K+ QR QEE RR E+ + Q+++R+ +++
Sbjct: 1376 ----------AEAHAQAKAQAEREAKELQQRM---QEEVVRREEAAVDAQQQKRSIQEEL 1422
Query: 759 QEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQ-----REQRFLPE 813
Q+ Q + Q +A + R RL +R R QL A ERQ+ Q
Sbjct: 1423 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVR-LQLEATERQRGGAEGELQALRAR 1481
Query: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRR----ERAQQLQEEEDGLQEDQERRRSQEQR 869
EE E ++RQ +E + L+ ++E ++R E A +++ E + +E Q ++ E+
Sbjct: 1482 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1541
Query: 870 RDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQ 929
R Q EE +R R A E+ R+ Q L+ + + E + KR E+
Sbjct: 1542 R-----LQAEEAERRLRQ------AEVERARQVQVALETAQRSAEAELQSKRA-SFAEKT 1589
Query: 930 YREEEQLQQEEEQL--LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE 987
+ E LQ+E + LREE E+R +Q+ E + +++ ++ E L R R + E
Sbjct: 1590 AQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE 1649
Query: 988 KKYREEEELQQEEEQLLRE-EREKRRRQEWERQYRKKDELQQEE------------EQLL 1034
+ +++ Q E E+ E ERE RRR + E Q ++ EL ++E +Q L
Sbjct: 1650 EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRL 1709
Query: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERE--TRRRQELERQYRKEEELQQEEEQ 1092
E+E RL+ Q ++ +L +EE L E T++RQELE + K ++ E E
Sbjct: 1710 AAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK---VRAEMEV 1766
Query: 1093 LL----REEPEKRRRQERERQCREEE-----ELQQEEEQL--LREEREKRRR---QELER 1138
LL R E E R E+ +Q E E EL +E +L L EE +++R+ ++ R
Sbjct: 1767 LLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAAR 1826
Query: 1139 QYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE--QEKRRQERE 1196
Q E E V E+ + E R + E E +E+E + +L +E Q +R +E+
Sbjct: 1827 QRAEAERVLAEKLAAIGEAT--RLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQA 1884
Query: 1197 RQYREE-EELQRQKRK----QRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFR 1251
Q++ + EE Q RK + R + D Q +E + + K +
Sbjct: 1885 AQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAEL 1944
Query: 1252 QLEDSQLRDR-----QSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE 1306
+LE ++R +S++ + Q++ E+ERRR + +R ++ L EE E
Sbjct: 1945 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER---VQKSLAAEE--E 1999
Query: 1307 AKRRDRKSQEEKQLLREEREEKRR-RQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365
A R+ + + EE + L+ + EE RR R+ +++ + QL QE ++ L+ +E+ F +
Sbjct: 2000 AARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ 2059
Query: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425
+ + Q + L++EQ + Q R + E R E ++ R +R+ + +Q+
Sbjct: 2060 QKEQELQ--QTLQQEQSVLDQLRG----EAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2113
Query: 1426 QERDRKFREEEQQVR--------------RQERERKFLEEEQQLRQ--------ERHRKF 1463
ER ++ EE+ Q R QE R+ E+ LRQ E+H+KF
Sbjct: 2114 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2173
Query: 1464 REEEQLLQEREEQ-------QLHRQERDRKFLEEEQQLRRQE-----RDRKFREQELRSQ 1511
E+ + + EQ QL + + L+EE Q + E R R E+EL S
Sbjct: 2174 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2233
Query: 1512 EPERKFLEEEQQLHRQQRQRKFLQEEQQLRR--QERGQQRRQDRDRKFR------EEEQL 1563
+ + L + + + + L+++ +R QE ++ +Q + R E +L
Sbjct: 2234 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2293
Query: 1564 RQEREE---QQLSRQERDRKFR----------------LEEQKVRRQEQERKFMEDEQQL 1604
RQ EE QQ + E+ K + L++QK QEQ R+ ED++Q+
Sbjct: 2294 RQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQM 2353
Query: 1605 RRQEGQQQLRQERDRKFREDEQLLQEREEQQLH----RQERDRKFLEEEPQLRRQEREQ- 1659
+Q ++ +R + QL E ++L R + EE+ Q R++ E+
Sbjct: 2354 AQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2413
Query: 1660 -QLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQ---Q 1715
+ H + +E+ L+Q E ++RQ+ D + + ERE++ LQ+E Q
Sbjct: 2414 GEKLHRTELATQEKVTLVQTLE---IQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2470
Query: 1716 LRRQELERKFREEEQLRQET---------EQEQLRRQERYRKILEEEQLRPE---REEQQ 1763
L+ +E++ ++EQL QET E++ L ++ER+ +E+E+ + E ++E
Sbjct: 2471 LKSEEMQTV--QQEQLLQETQALQQSFLSEKDSLLQRERF---IEQEKAKLEQLFQDEVA 2525
Query: 1764 LRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE-EEQLRQEREE-QQLRPQQRDGKY 1821
+Q R+ + R+++Q+ QER+ +E+ R+ E EE +R+++EE QQL Q+R +
Sbjct: 2526 KAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEE 2585
Query: 1822 RWEEEQLQLEEQEQRL-RQERDRQYRAEEQFATQEKSRR-------------EEQELWQE 1867
EE +L EQ Q L Q R +EE A+Q + + E E
Sbjct: 2586 LLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHS 2645
Query: 1868 EEQKRRQERERKLREEHI---RRQQKEEQRHRQVGEIKSQEGKGH 1909
+ RR+ ++L+E I Q+ Q H V E+ +E H
Sbjct: 2646 FDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRH 2690
Score = 321 bits (822), Expect = 5e-87
Identities = 452/1778 (25%), Positives = 777/1778 (43%), Gaps = 303/1778 (17%)
Query: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ--LRREQQL-----------RR 421
Q LRR+ QL R L + L+ E+Q + L Q LR Q R
Sbjct: 897 QSLRRDVQLIRSWSLATFRTLKPEEQRQALHSLELHYQAFLRDSQDAGGFGPEDRLMAER 956
Query: 422 E------------QQLRREQEEERHEQKHEQERREQRLKREQEERRDW----LKREEETE 465
E Q L + +EE Q+ E ++ RL+ E E R L ++E
Sbjct: 957 EYGSCSHHYQQLLQSLEQGAQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPA 1016
Query: 466 RHEQERRKQQLKRDQEEE-----------RRERWLKLEEEERREQQERREQQLRREQ-EE 513
R +R +Q K E E E+ L L E R E +L + E+
Sbjct: 1017 RECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQ 1076
Query: 514 RREQRLKRQEEEERLQQRLR----SEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
R E+ + + +R +E+ LR +E+ +E LE + + R
Sbjct: 1077 VRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLR 1136
Query: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER 629
Q E + + R + R +E ERL+QR +VE ER Q L ER
Sbjct: 1137 AQAEAQQPTF--DALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLL-------ER 1187
Query: 630 RQQLLKSEEQEERRQQQLRREQQERRE---------QRLKREEEE---------ERLEQR 671
Q +L + +R +QL R+ + RE Q +R +E+ + + ++
Sbjct: 1188 WQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQ 1247
Query: 672 LKREH---EEERREQELAEEEQEQARERIKS------RIPKWQWQLESEADARQSKVYSR 722
L++E EE R E EE Q A++ I + ++ ++ QLE A + +
Sbjct: 1248 LRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK-----K 1302
Query: 723 PRKQEGQRRRQEQEEKRRRRESEL----------------QWQEEERAHRQQQEEEQRRD 766
P+ Q G ++ R SEL + +EEER QQ+ EE+ R
Sbjct: 1303 PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER- 1361
Query: 767 FTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQR-EQRFLPEEEEKEQRRRQRR 825
+ E E+ RQ A + Q ER+ A+E QQR ++ + EE ++Q+R
Sbjct: 1362 ---LAEVEAALEKQRQLAEAHAQAKAQAERE--AKELQQRMQEEVVRREEAAVDAQQQKR 1416
Query: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR 885
++ELQ L + + + + +A+Q + E + R R +E+ R R QLE ++R
Sbjct: 1417 SIQEELQQLRQSSEAEIQAKARQAEAAE------RSRLRIEEEIRVV--RLQLEATERQR 1468
Query: 886 ---RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQER------------QY 930
L A A E+ +++ QEE E L+R+ +++ +R+ Q
Sbjct: 1469 GGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAA 1528
Query: 931 REEEQLQQ--EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK 988
RE+++ Q EE +L EE E+R RQ + R+ + + ++ E + +R EK
Sbjct: 1529 REKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEK 1588
Query: 989 KYREEEELQQEEEQL--LREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
+ E LQ+E + LREE E+R +Q+ E + R ++E ++E E+ + E RL+ +
Sbjct: 1589 TAQLERSLQEEHVAVAQLREEAERRAQQQAEAE-RAREEAERELERWQLKANEALRLRLQ 1647
Query: 1047 ERQYREEEELQQEEEQLLGEE--RETRRRQELERQYRKEEELQQEE----EQLLREEPEK 1100
+ +++ L Q E + EE RE RRR + E Q ++ EL ++E QL ++
Sbjct: 1648 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1707
Query: 1101 RRRQERER-QCREEEELQQEEEQLLREEREK---------RRRQELERQYREEEEVQQEE 1150
R E+E + R E E +++ QLL EE + ++RQELE E +V+ E
Sbjct: 1708 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA---ELAKVRAEM 1764
Query: 1151 EQLL----REEPEKRRRQELERQYREEE-----ELQQEEEQLLREEQEKRRQERERQYRE 1201
E LL R E E R E +Q E E EL +E +L +E +RQ RQ E
Sbjct: 1765 EVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ---RQLAE 1821
Query: 1202 EEELQRQKRKQRYRDEDQRS-DLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQL-- 1258
E+ +++ +R E + + + E E A+++ K ENE+ R+L + +
Sbjct: 1822 EDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKE-----KEAENERLRRLAEDEAFQ 1876
Query: 1259 RDRQSQQDLQH-------LLGEQQERDREQERRRWQQRD----RHFPEEEQLEREEQKEA 1307
R R +Q QH L ++ D E ER++ D R EEE L + E
Sbjct: 1877 RRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEK 1936
Query: 1308 KR-----------RDRKSQEEKQLLREEREEKRRRQ-----ETDRKFREEEQLLQEREEQ 1351
R R + E+ +E+ E + RQ E +R+ RE E ER ++
Sbjct: 1937 AAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE----ERVQK 1992
Query: 1352 PLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR-------------QERERKFLKEEQQ 1398
L +E + R+ L E+ + +EE +RLR QE +K L+ E++
Sbjct: 1993 SLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEK 2052
Query: 1399 LRC---QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ-ERE----RKFLE 1450
Q++EQ+L+Q ++ +Q E R+ EE ++ R Q ERE R+ +E
Sbjct: 2053 AHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2112
Query: 1451 EEQQLRQERHRKFREE-------EQLLQEREEQQLHRQERDRKFLEEEQQLRRQ-ERDRK 1502
E ++L+Q + + E+L +E E++ R + ++ L ++Q + E+ +K
Sbjct: 2113 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2172
Query: 1503 FREQELRSQ-EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561
F EQ LR + + E++ QL Q+ L EE Q + E + RQ R EEE
Sbjct: 2173 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQ---RSQVEEE 2229
Query: 1562 QLRQEREEQQLSRQERDRKFRLEEQK----VRRQEQERKFMEDEQQLRRQEGQQQLRQER 1617
+ ++LS+ K R+E + +R ++ ++F+++E + +Q ++ R
Sbjct: 2230 LFSVRVQMEELSKL----KARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV 2285
Query: 1618 DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQ 1677
+ E +L Q EE ++ K L+E+ Q ++ + + E +LLQ
Sbjct: 2286 AAQ--EAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT----------RLKAEAELLQ 2333
Query: 1678 EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ 1737
+ +E QE+ R+ +E+++Q+ +Q L EE Q ++ LE + + + ++ E E+
Sbjct: 2334 QQKELA---QEQARRLQEDKEQMAQQ------LAEETQGFQRTLEAERQRQLEMSAEAER 2384
Query: 1738 EQLRRQERYRKILEEEQLRPEREEQQLRRQERD--RKFREEEQLRQER----EEQQLRSQ 1791
+LR E R Q R E + Q+ R+Q + K E QE+ + +++ Q
Sbjct: 2385 LKLRVAEMSRA-----QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2439
Query: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYR----- 1846
+SD + E E ++ + QQ + + E++Q +QEQ L++ + Q
Sbjct: 2440 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2499
Query: 1847 ----AEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIK 1902
E+F QEK++ E+ L+Q+E K +Q RE + +RQQ++ ++ RQ
Sbjct: 2500 DSLLQRERFIEQEKAKLEQ--LFQDEVAKAQQLREEQ------QRQQQQMEQERQRLVAS 2551
Query: 1903 SQEGKGHGRLLEPGTHQFASVPVRSSPLYEYIQEQRSQ 1940
+E + E G + + L + Q++R Q
Sbjct: 2552 MEEARRRQHEAEEGVRR------KQEELQQLEQQRRQQ 2583
Score = 311 bits (798), Expect = 3e-84
Identities = 324/1270 (25%), Positives = 597/1270 (47%), Gaps = 197/1270 (15%)
Query: 98 EKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE- 156
+ +A+ + + LQ R QEE RR + ++ + +R Q+ +Q R+ +E E Q++
Sbjct: 1381 QAKAQAEREAKELQQRMQEEVVRR---EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKA 1437
Query: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERR-AEEEQLQSCKGHETEEFPDEEQLRRREL 215
+Q +R R R +EE+ R + + E +R E +LQ+ + EE +++ + E
Sbjct: 1438 RQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRA-RAEEAEAQKRQAQEEA 1496
Query: 216 LELRRKGREEKQQQRR---ERQDRVFQEEEEKEWRKRETVLRKE--------EEKLQEEE 264
LRR+ ++E Q++R+ E RV E E ++R +E E +L++ E
Sbjct: 1497 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1556
Query: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
+R R++Q E ++ EL+ +R ++ +L R Q + RE+ E R +Q
Sbjct: 1557 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1616
Query: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
Q E+ E E++L R Q + E R Q EE +Q+ + E E+++++ RE + R
Sbjct: 1617 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1676
Query: 385 ---REQQLRR----EQQLRREQQLRR---EQQLRREQQLRR----------EQQLRREQQ 424
EQ +R+ EQ+L +++QL +Q+L EQ+L R ++QL E+
Sbjct: 1677 GKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEEL 1736
Query: 425 LRREQEEERHEQKHEQ-ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD---- 479
R ++E QK ++ E +++ E E R EE R E+ KQ+L+ +
Sbjct: 1737 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1796
Query: 480 -------------QEEERRERWLKLEEEERREQQERR-----------------EQQLRR 509
EE +R+R L E+ R+ + R E ++
Sbjct: 1797 RELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL 1856
Query: 510 EQEERREQRLKRQEEEERLQQRLRSEQ--QLRREQEERREQLLKR-----EEEKRLEQER 562
+++E +RL+R E+E Q+R EQ Q + + EER QL K E +K L ++
Sbjct: 1857 KEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDT 1916
Query: 563 REQRLKREQE---------------------------ERRDQLLKREEER---------- 585
QR + E+E D L +E+
Sbjct: 1917 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1976
Query: 586 -RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
++R +RE EER+++ L EE E Q + + ++R + + E ++L + EQE RQ
Sbjct: 1977 AEEERRRREAEERVQKSLAAEE-EAARQRKAALEEVERLKAKVEEARRLRERAEQESARQ 2035
Query: 645 QQLRREQQERREQRLKR------EEEEERLEQRLKREH---EEERREQELAE---EEQEQ 692
QL +E ++R Q ++ +++E+ L+Q L++E ++ R E E A EE E+
Sbjct: 2036 LQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2095
Query: 693 ARERIKSRIPKWQWQLESEADARQS---KVYSRPRKQ---EGQRRRQEQEEKRRRRESEL 746
AR + + + + Q+E +QS + +R + Q E R+ EQE RR + +
Sbjct: 2096 ARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQA 2155
Query: 747 QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA-----RPPLREQRERQLRAE 801
++++ A + ++ ++ + T + +A+ + E RL + L ++ ++L+AE
Sbjct: 2156 ALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2215
Query: 802 ERQQREQRFLPEEE--------EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
+ QR EEE E+ + + R E E L +++ QR LQEE
Sbjct: 2216 ATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR-----FLQEEA 2270
Query: 854 DGLQE--DQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEE 911
+ +++ ++ R S + + R EE+ ++R AL E++ KE+ +E
Sbjct: 2271 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQR-------ALAEKMLKEKMQAVQEAT 2323
Query: 912 ELQRE----EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967
L+ E +++K QEQ R+ +E++ +Q +QL E + +R E ERQ + + +
Sbjct: 2324 RLKAEAELLQQQKELAQEQARRLQEDK--EQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2381
Query: 968 QKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR----QEWERQYRKK 1023
+ +L E + + + E R ++ ++ E+L R E + + Q E Q ++
Sbjct: 2382 AERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2441
Query: 1024 D-ELQQEEEQLLREEREKRRLQERER--QYREEEELQQEEEQLLGEERETRRR--QELER 1078
D + ++ E + EREK +LQ+ + Q + EE ++EQLL E + ++ E +
Sbjct: 2442 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDS 2501
Query: 1079 QYRKEEELQQEE---EQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135
++E ++QE+ EQL ++E K +Q RE Q R++++++QE ++L+ E RR
Sbjct: 2502 LLQRERFIEQEKAKLEQLFQDEVAK-AQQLREEQQRQQQQMEQERQRLVASMEEARR--- 2557
Query: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
RQ+ EE V++++E+L Q+LE+Q R++EEL EE Q LRE+ + ++
Sbjct: 2558 --RQHEAEEGVRRKQEEL----------QQLEQQRRQQEELLAEENQRLREQLQLLEEQH 2605
Query: 1196 ERQYREEEEL 1205
EE+
Sbjct: 2606 RAALAHSEEV 2615
Score = 212 bits (539), Expect = 3e-54
Identities = 221/808 (27%), Positives = 387/808 (47%), Gaps = 87/808 (10%)
Query: 88 ALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRR--QKRQEQE 145
A+G+AT L E KE+ + R+ + F+ R+LEE+ Q + ++R Q
Sbjct: 1841 AIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQ--RRRLEEQAAQHKADIEERLAQL 1898
Query: 146 RELAEGEEQSEKQERLEQRDRQRR--DEELWRQRQEWQEREERRAE-EEQLQSCKGHETE 202
R+ ++ E + +K +E RQRR +EE+ + +++ +AE E +L + +
Sbjct: 1899 RKASDSELERQK-GLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA-- 1955
Query: 203 EFPDEEQLRRRELLEL----RRKGREEKQQQRRERQDRVFQE--EEEKEWRKRETVLRKE 256
E+ LR +E EL +R+ E++++RRE ++RV + EE+ R+R+ L +
Sbjct: 1956 ----EDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2011
Query: 257 EE-KLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL---RREQQLRRKQEE 312
E K + EE +R RE E+E + QE ++R + E++ ++EQ+L++ ++
Sbjct: 2012 ERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQ 2071
Query: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER 372
E+ + R E + R EE E R Q ER Q RR+ EE R +Q EQ + R
Sbjct: 2072 EQSVLDQLRGEAEAARRAAEEAEE---ARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2128
Query: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLR----------REQQLRREQQLRRE 422
+ Q E +LR+E + ++ + EQ R++Q EQ LR++ Q+ +E
Sbjct: 2129 AQAQAAAE-KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQE 2187
Query: 423 QQLRREQEEERHEQKHEQERREQRLKREQEE---RRDWLKREEETERHEQERRKQQLKRD 479
R Q EE QK+ + QRLK E E +R ++ E + R + E + R
Sbjct: 2188 LTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2247
Query: 480 QEEER------RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
+ E R ++ + +EE + ++ E+ R + RL++ EE+ QQR
Sbjct: 2248 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2307
Query: 534 SEQQLRREQEERRE--------QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585
+E+ L+ + + +E +LL++++E EQ RR Q E +E+ Q L E +
Sbjct: 2308 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ----EDKEQMAQQLAEETQG 2363
Query: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ 645
Q+ L+ E++ +LE + E ++ E R Q E+ + R+Q E E+ +
Sbjct: 2364 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ---AEEIGEKLHRT 2420
Query: 646 QLRREQQERREQRLK-REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKW 704
+L +++ Q L+ + ++ + +RL+ E RE+E ++E + + + +
Sbjct: 2421 ELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQ 2480
Query: 705 QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR 764
Q QL E A Q S + R EQE+ + Q ++E A QQ EEQ+
Sbjct: 2481 QEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE-----QLFQDEVAKAQQLREEQQ 2535
Query: 765 RDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQR 824
R +++ E+ RQRL A + E R RQ AEE +R+Q EE +Q +QR
Sbjct: 2536 RQ-------QQQMEQERQRLVA--SMEEARRRQHEAEEGVRRKQ------EELQQLEQQR 2580
Query: 825 REREKELQFLEEEEQLQRRERAQQLQEE 852
R++E+ L EE + RE+ Q L+E+
Sbjct: 2581 RQQEE----LLAEENQRLREQLQLLEEQ 2604
Score = 151 bits (382), Expect = 5e-36
Identities = 162/632 (25%), Positives = 294/632 (46%), Gaps = 80/632 (12%)
Query: 99 KRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQ-----------ERE 147
+RA + +E+ +Q R+ RR Q+EE +R +Q +EQ E+
Sbjct: 2087 RRAAEEAEEARVQAEREAAQSRR------QVEE--AERLKQSAEEQAQARAQAQAAAEKL 2138
Query: 148 LAEGEEQSEKQERLEQ---RDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
E E+++ ++ + EQ R +Q D E+ + ++ ++ ++A+ EQ + + EE
Sbjct: 2139 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2198
Query: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQD----RVFQEEEEK-----EWRKRETVLRK 255
++ L EL L+ + E +Q+ + ++ RV EE K E R +LR
Sbjct: 2199 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD 2258
Query: 256 EE--EKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ--EEEQQQQRLRREQQLRRK-- 309
++ ++ +EE ++ +++ EE +L + QE R RQ EE+ QQR E+ L+ K
Sbjct: 2259 KDNTQRFLQEEAEKMKQVAEEAARL-SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQ 2317
Query: 310 --QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE------EERRE 361
QE R + + E +QQ+ Q++ RR Q E +E+ QQL E + E R+
Sbjct: 2318 AVQEATRLKAEAELLQQQKELAQEQARRLQ----EDKEQMAQQLAEETQGFQRTLEAERQ 2373
Query: 362 QQLRREQEEER---REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
+QL E ER R ++ R Q E R +Q + +L ++++ Q
Sbjct: 2374 RQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT 2433
Query: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR 478
L ++Q E E E ER +++L Q+E + + EE + +QE+ Q+ +
Sbjct: 2434 LEIQRQQSDHDAERLREAIAELEREKEKL---QQEAKLLQLKSEEMQTVQQEQLLQETQA 2490
Query: 479 DQEEERRERWLKLEEEERREQQERREQQL-----RREQEERREQRLKRQEEEERLQQRLR 533
Q+ E+ L+ E EQ++ + +QL + Q+ R EQ+ ++Q+ E+ Q+ +
Sbjct: 2491 LQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVA 2550
Query: 534 SEQQLRREQEERREQLLKREEE-KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592
S ++ RR Q E E + +++EE ++LEQ+RR+Q ++LL E +R +++L+
Sbjct: 2551 SMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ----------EELLAEENQRLREQLQL 2600
Query: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRRE-- 650
+E+ EEV + + R+ + +E + E LRR+
Sbjct: 2601 LEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGP------AAEAEPEHSFDGLRRKVS 2654
Query: 651 QQERREQRLKREEEEERLEQRLKREHEEERRE 682
Q +E + EE +RL Q E RRE
Sbjct: 2655 AQRLQEAGILSAEELQRLAQGHTTVDELARRE 2686
Score = 96.3 bits (238), Expect = 3e-19
Identities = 86/335 (25%), Positives = 166/335 (49%), Gaps = 42/335 (12%)
Query: 80 KVAQACYYALGQATGLDEEKRARCDGKESLLQDRR------QEEDQRRFEPRDRQLEEEP 133
K+ Q A + E R R +E L Q R +E+ Q E + E E
Sbjct: 2272 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAEL 2331
Query: 134 GQRRRQKRQEQERELAEGEEQSEKQ--------ERLEQRDRQRRDE-----ELWRQRQEW 180
Q++++ QEQ R L E +EQ +Q +R + +RQR+ E E + R
Sbjct: 2332 LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAE 2391
Query: 181 QEREERRAEEEQLQSCKGHET-------EEFPDEEQLRRRELLELRRKGREEKQQQRRE- 232
R + RAEE+ + K E E +E++ + LE++R+ + ++ RE
Sbjct: 2392 MSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREA 2451
Query: 233 ------RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRK---LER 283
++++ QE + + + E ++E+ LQE + +Q L E++ L++ +E+
Sbjct: 2452 IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQ 2511
Query: 284 QELRRER--QEEEQQQQRLRREQQLRRKQEEERREQ----QEERREQQERREQQEERREQ 337
++ + E+ Q+E + Q+LR EQQ +++Q E+ R++ EE R +Q E+ R+++
Sbjct: 2512 EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQE 2571
Query: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEER 372
+L++ +++RR+Q+ +E +R +QL+ +E+ R
Sbjct: 2572 ELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHR 2606
Score = 37.4 bits (85), Expect = 0.14
Identities = 73/313 (23%), Positives = 122/313 (38%), Gaps = 57/313 (18%)
Query: 933 EEQLQQEEEQLLREEREKRRRQER----ERQYRKDKKLQQKEEQLL--GEEPEKRRRQER 986
E+QL+ E E+L +R + Q E Q + L Q + +LL G+ P++ ER
Sbjct: 381 EKQLRSEFERLECLQRIVTKLQMEAGLCEEQLNQADALLQSDVRLLAAGKVPQRAGEVER 440
Query: 987 E-KKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ-EEEQLLR--------- 1035
+ K L + Q L++ R + Q + R YR + L E LR
Sbjct: 441 DLDKADSMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPA 500
Query: 1036 EEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE----------LERQYRKEEE 1085
+ + LQ +R+ E+ + + LL E + R + +E Q
Sbjct: 501 TQVAQVTLQSVQRRPELEDSTLRYLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRG 560
Query: 1086 LQQEEEQLLREEPEKRRRQERE---------RQCREEEELQQEEEQLLREEREKRRRQEL 1136
L Q E+ R + E+ R E + R C +LQ + LL + + R E
Sbjct: 561 LHQSIEEF-RAKIERARSDEGQLSPATRGAYRDCLGRLDLQYAK--LLNSSKARLRSLES 617
Query: 1137 ERQY-------------REEEEV-----QQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178
+ +EEEEV + ++E +ELE + ++ +ELQ
Sbjct: 618 LHSFVAAATKELMWLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQN 677
Query: 1179 EEEQLLREEQEKR 1191
++LLRE+ R
Sbjct: 678 AGDRLLREDHPAR 690
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 342 bits (876), Expect = 3e-93
Identities = 446/1785 (24%), Positives = 774/1785 (43%), Gaps = 216/1785 (12%)
Query: 114 RQEEDQRRFEPRDRQL-EEEPG----------QRRRQKRQEQER------ELAEGEEQSE 156
R +D F P DR + E E G Q Q QE+ R EL + Q E
Sbjct: 906 RDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGAQEESRCQRCISELKDIRLQLE 965
Query: 157 KQE-RLEQRDRQRRDEELWRQ-RQEWQEREERRAEEEQL------QSCKGHETEEFPDEE 208
E R R R D+E R+ Q E+++ +AE E L S + + P+
Sbjct: 966 ACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPS 1025
Query: 209 QL--RRRELLELRRKGREEKQQQRRERQDRVFQEEEE------KEWRKRETVLRKEEEKL 260
R LEL E+ + ++ E+ + + + E VLR EE+L
Sbjct: 1026 PAAPTLRSELELTLGKLEQVRS-----LSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQL 1080
Query: 261 QEEE--PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318
+E + P EL+ + L+KL R + ++ + + LR Q++ + ++ E+
Sbjct: 1081 KEAQAVPATLPELEATKASLKKL-RAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERD 1139
Query: 319 EERREQQERREQQEERREQQLRREQEERRE-QQLRREQEEERRE-QQLRREQEEERREQQ 376
E +ER Q ER + L + +RE +QL R+ R L ++ RR Q+
Sbjct: 1140 VEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQE 1199
Query: 377 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE---- 432
+ L Q +R +QLR+EQ L E + R + E Q +Q + ++ E
Sbjct: 1200 QIQAMPLADSQAVR--EQLRQEQALLEE--IERHGEKVEECQRFAKQYINAIKDYELQLV 1255
Query: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR----------KQQLKRDQEE 482
++ + E + + Q ++ + H E + L+R +EE
Sbjct: 1256 TYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEE 1315
Query: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
ER + EE ER + E ++ R+ E + + + + E + LQQR++ E+ +RRE+
Sbjct: 1316 ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ-EEVVRREE 1374
Query: 543 EERREQLLKREEEKRLEQERRE-----QRLKREQEERRDQLLKREEERRQQRLKREQEER 597
Q KR ++ L+Q R+ Q R+ E L+ EEE R RL+ E ER
Sbjct: 1375 AAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATER 1434
Query: 598 -----------LEQRLKREEVERLEQEERREQRLKREEPEEERRQQ----LLKSEEQEER 642
L R + E ++ + +E E+ ++ + E +R++Q L + E
Sbjct: 1435 QRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAE 1494
Query: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIP 702
++ +R Q E RL+ EE E RL Q E E R+ Q E Q A ++S+
Sbjct: 1495 AAREKQRALQALEELRLQAEEAERRLRQ---AEVERARQVQVALETAQRSAEAELQSKRA 1551
Query: 703 KW-QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES---ELQ-WQ---EEERA 754
+ + + E ++ V ++E +RR Q+Q E R RE EL+ WQ E
Sbjct: 1552 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1611
Query: 755 HRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE- 813
R Q EE ++ Q +AE++ E + R EQ RQ E++ +QR L E
Sbjct: 1612 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEG 1671
Query: 814 --------EEEKEQRRRQRREREKELQFLEEE-EQLQRR-----ERAQQLQEEEDGLQED 859
E+E + R + + E++ Q LEEE +LQR ++ Q+L+ E ++ +
Sbjct: 1672 TAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAE 1731
Query: 860 QE-----RRRSQEQRR--DQKWRWQLEEERKRRRHTLYAKP---ALQEQLRKEQQLLQEE 909
E + R++E+ R +K + +LE E R R AL E+ ++++Q L EE
Sbjct: 1732 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQ-LAEE 1790
Query: 910 EEELQREEREK-------------RRRQEQERQYREEEQLQQEEEQLLREEREKRRR--- 953
+ QR E E+ R + E E +E+E + +L +E +RRR
Sbjct: 1791 DAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEE 1850
Query: 954 ---------QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
+ER Q RK + + ++ L E+ ++RRQ E+ + ++
Sbjct: 1851 QAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKA 1910
Query: 1005 REEREKRR-RQEWERQYRKKD--ELQQEEEQLLREEREKRRLQERERQYR----EEEELQ 1057
E E R R E R K+ EL+ ++ L E E+RR + ER + EEE +
Sbjct: 1911 ELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR 1970
Query: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117
Q + L ER + +E R + E+ + QL +E +KR + E + ++ +
Sbjct: 1971 QRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 2030
Query: 1118 QEEEQLLREERE--KRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175
QE +Q L++E+ + R E E R EE ++ Q RE + R RQ E E
Sbjct: 2031 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR------RQVEEAER 2084
Query: 1176 LQQE-EEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234
L+Q EEQ Q + E+ R+ E+E +R + +Q + Q +D E EK
Sbjct: 2085 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADA----EMEKHKK 2140
Query: 1235 VRDNKVYCKGRENEQFR----QLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRD 1290
+ + K + ++ QLE++ + ++LQ L E E R++ + +
Sbjct: 2141 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2200
Query: 1291 RHFPEEEQLEREEQKEAKRRD---RKSQEEKQLLREEREEKRRRQETDRKF----REEEQ 1343
EE + + + EA+ R R ++ L+EE E+ ++ E + +E +
Sbjct: 2201 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2260
Query: 1344 LLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQE 1403
L Q EE +++ K +E+++ ++ + E + L++Q K L +EQ R QE
Sbjct: 2261 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQ----KELAQEQARRLQE 2316
Query: 1404 REQQLRQDRDRKF----------REEEQQLSRQERDRKFREEEQ---QVRRQERERKFLE 1450
++Q+ Q + R+ + ++S + K R E Q R +E ++F +
Sbjct: 2317 DKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRK 2376
Query: 1451 EEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE--- 1507
+ +++ ++ HR ++ + + ++ RQ+ D + + ER+++ +QE
Sbjct: 2377 QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKL 2436
Query: 1508 LRSQEPERKFLEEEQQLHRQQR-QRKFLQEEQQLRRQERG-QQRRQDRDRKFREE----E 1561
L+ + E + +++EQ L Q Q+ FL E+ L ++ER +Q + ++ F++E +
Sbjct: 2437 LQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQ 2496
Query: 1562 QLRQERE-EQQLSRQERDRKFRLEEQKVRRQ----EQERKFMEDEQQLRRQEGQQ-QLRQ 1615
QLR+E++ +QQ QER R E+ RRQ E R+ E+ QQL +Q QQ +L
Sbjct: 2497 QLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLA 2556
Query: 1616 ERDRKFREDEQLLQEREEQQLHRQER--------DRKFLEEEPQLRRQEREQQLRHDRDR 1667
E +++ RE QLL+E+ L E + L E + H D
Sbjct: 2557 EENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDG 2616
Query: 1668 KFRE-EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ 1711
R+ Q LQE +R + +L R+E R +LQ
Sbjct: 2617 LRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQ 2661
Score = 326 bits (836), Expect = 1e-88
Identities = 360/1355 (26%), Positives = 617/1355 (45%), Gaps = 193/1355 (14%)
Query: 113 RRQEEDQR-----RFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQ 167
RR EE++R R E R+R E E E++R+LAE Q++ Q E ++ Q
Sbjct: 1310 RRMEEEERLAEQQRAEERERLAEVEAA-------LEKQRQLAEAHAQAKAQAEREAKELQ 1362
Query: 168 RR--DEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE- 224
+R +E + R+ ++++R+ +E+LQ QLR+ E++ K R+
Sbjct: 1363 QRMQEEVVRREEAAVDAQQQKRSIQEELQ--------------QLRQSSEAEIQAKARQA 1408
Query: 225 ---EKQQQRRERQDRVFQEEEEKEWRKR---ETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
E+ + R E + RV + + E R+R E L+ + +E E Q+ R+ QEE E+L
Sbjct: 1409 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK-RQAQEEAERL 1467
Query: 279 RKLERQELRRERQEEEQQQQRLRREQQLRRKQE------EERREQQEERREQQERREQQE 332
R+ + E +R+RQ E + R++ E + R+++ EE R Q EE E++ R+ + E
Sbjct: 1468 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE-AERRLRQAEVE 1526
Query: 333 ERREQQLRREQEER---REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
R+ Q+ E +R E Q +R E+ Q R QEE QLR E + R +QQ
Sbjct: 1527 RARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQA 1586
Query: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
E+ ++ QL+ + LR Q Q + + E +QK E ER +R +
Sbjct: 1587 EAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGK 1646
Query: 450 EQEE---RRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506
+E+ +R+ ++E E +R E QQ ++E R L+ E E+ +Q++ E++
Sbjct: 1647 AEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR---LRAETEQGEQQRQLLEEE 1703
Query: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566
L R Q E KRQE E L ++R E E + EEE R E+ +QR
Sbjct: 1704 LARLQREAAAATQKRQELEAEL-------AKVRAEMEVLLASKARAEEESRSTSEKSKQR 1756
Query: 567 LKRE------------------QEERRDQLLKREEERRQQ------------------RL 590
L+ E +E +R + L E+ RQ+ RL
Sbjct: 1757 LEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRL 1816
Query: 591 KREQEERL-EQRLKREEVERLEQEERREQRLKREEPE------EERRQQLLKSEEQEERR 643
K E E L E+ + E + RL ++E ++R E+ EER QL K+ + E R
Sbjct: 1817 KTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELER 1876
Query: 644 QQQL------RREQQERREQRLK--------------------REEEEERLEQRLKREHE 677
Q+ L +R Q E LK R E+ L + + E E
Sbjct: 1877 QKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELE 1936
Query: 678 EERREQELAEEE--QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQ 735
R+ Q AEEE + +A ER++ + + + + A +V K E RR +E+
Sbjct: 1937 AARQRQLAAEEERRRREAEERVQKSLAA-EEEAARQRKAALEEVERLKAKVEEARRLRER 1995
Query: 736 EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRE 795
E+ R+ +L +E A ++ Q EE+ F Q + +E + +Q S LR + E
Sbjct: 1996 AEQESARQLQL---AQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2052
Query: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDG 855
RA E + E+ + E E Q RRQ E E+ Q EEQ Q R +AQ E+
Sbjct: 2053 AARRAAE--EAEEARVQAEREAAQSRRQVEEAERLKQ--SAEEQAQARAQAQAAAEKLRK 2108
Query: 856 LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL----LQEEEE 911
E + RR+Q ++ + + + E + +H +A+ L+++ + EQ+L LQ EE
Sbjct: 2109 EAEQEAARRAQAEQAALRQKQAADAEME--KHKKFAEQTLRQKAQVEQELTTLRLQLEET 2166
Query: 912 ELQR---EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
+ Q+ +E +R + E R+ Q+++E + + E + + R + L+
Sbjct: 2167 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD 2226
Query: 969 KE--EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
K+ ++ L EE EK ++ E + + L EE ++R E+ ++K +
Sbjct: 2227 KDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQA 2286
Query: 1027 QQEEEQLLRE----EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK 1082
QE +L E +++K QE+ R+ +E++E Q +QL E + +R E ERQ +
Sbjct: 2287 VQEATRLKAEAELLQQQKELAQEQARRLQEDKE--QMAQQLAEETQGFQRTLEAERQ--R 2342
Query: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYRE 1142
+ E+ E E+L E R Q R EE+ Q+ +Q E EK R EL Q +
Sbjct: 2343 QLEMSAEAERLKLRVAEMSR-----AQARAEEDAQRFRKQ-AEEIGEKLHRTELATQEKV 2396
Query: 1143 EEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREE 1202
E ++ + +R R+ + RE+E+LQQE + L + +E + ++E+ +E
Sbjct: 2397 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQET 2456
Query: 1203 EELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQ 1262
+ LQ Q + E + S L+ + E+E A + + + +Q R E+ Q + +Q
Sbjct: 2457 QALQ-----QSFLSE-KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR--EEQQRQQQQ 2508
Query: 1263 SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR 1322
+Q+ Q L+ +E R Q E E+ R +Q+E ++ +++ +++++LL
Sbjct: 2509 MEQERQRLVASMEEARRRQH------------EAEEGVRRKQEELQQLEQQRRQQEELLA 2556
Query: 1323 EEREEKRRRQETDRKFREEEQLLQEREEQPLRRQE 1357
EE +++ RE+ QLL+E+ L E
Sbjct: 2557 EE----------NQRLREQLQLLEEQHRAALAHSE 2581
Score = 324 bits (830), Expect = 6e-88
Identities = 461/1845 (24%), Positives = 811/1845 (43%), Gaps = 259/1845 (14%)
Query: 253 LRKEEEK--LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQ 310
L+ EE++ L E Q L++ ++ L ER+ + Q L +
Sbjct: 885 LKPEEQRQALHSLELHYQAFLRDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGA 944
Query: 311 EEERREQQ--EERREQQERREQQEERREQQLR--------REQEERREQQLRREQEEERR 360
+EE R Q+ E ++ + + E E R +LR RE +R +Q + + E E
Sbjct: 945 QEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGL 1004
Query: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
+ + R E E+ L + LR E +L L + +Q+R + E+
Sbjct: 1005 GKGVARLSAEA--EKVLALPEPSPAAPTLRSELELT----LGKLEQVRSLSAIYLEKLKT 1058
Query: 421 REQQLRREQEEERHEQKHEQERREQRLKR----EQEERRDWLKR---EEETERHEQERRK 473
+R Q E + HE++ +E + E E + LK+ + E ++ + +
Sbjct: 1059 ISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALR 1118
Query: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
+L+ QE R + E + E+ R QL + Q RQ E E+L ++LR
Sbjct: 1119 DELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLR 1178
Query: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE 593
+ E + L ++ R QE+ + + + R+QL R+E+ + ++R
Sbjct: 1179 YYR-------ESADPLGAWLQDARRRQEQIQAMPLADSQAVREQL--RQEQALLEEIERH 1229
Query: 594 QEERLE-QRLKREEVERLEQEERREQRLKRE-EP--EEERRQQLLKSEEQEERRQQQLRR 649
E+ E QR ++ + ++ E + K + EP ++ ++ E + LR
Sbjct: 1230 GEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRT 1289
Query: 650 EQQERR----------EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
E + L+R EEEERL ++ + E E E E A E+Q Q
Sbjct: 1290 HYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQL------ 1343
Query: 700 RIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQ- 758
+EA A+ R K+ QR QEE RR E+ + Q+++R+ +++
Sbjct: 1344 ----------AEAHAQAKAQAEREAKELQQRM---QEEVVRREEAAVDAQQQKRSIQEEL 1390
Query: 759 QEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQ-----REQRFLPE 813
Q+ Q + Q +A + R RL +R R QL A ERQ+ Q
Sbjct: 1391 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVR-LQLEATERQRGGAEGELQALRAR 1449
Query: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRR----ERAQQLQEEEDGLQEDQERRRSQEQR 869
EE E ++RQ +E + L+ ++E ++R E A +++ E + +E Q ++ E+
Sbjct: 1450 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1509
Query: 870 RDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQ 929
R Q EE +R R A E+ R+ Q L+ + + E + KR E+
Sbjct: 1510 R-----LQAEEAERRLRQ------AEVERARQVQVALETAQRSAEAELQSKRA-SFAEKT 1557
Query: 930 YREEEQLQQEEEQL--LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE 987
+ E LQ+E + LREE E+R +Q+ E + +++ ++ E L R R + E
Sbjct: 1558 AQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE 1617
Query: 988 KKYREEEELQQEEEQLLRE-EREKRRRQEWERQYRKKDELQQEE------------EQLL 1034
+ +++ Q E E+ E ERE RRR + E Q ++ EL ++E +Q L
Sbjct: 1618 EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRL 1677
Query: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERE--TRRRQELERQYRKEEELQQEEEQ 1092
E+E RL+ Q ++ +L +EE L E T++RQELE + K ++ E E
Sbjct: 1678 AAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK---VRAEMEV 1734
Query: 1093 LL----REEPEKRRRQERERQCREEE-----ELQQEEEQL--LREEREKRRR---QELER 1138
LL R E E R E+ +Q E E EL +E +L L EE +++R+ ++ R
Sbjct: 1735 LLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAAR 1794
Query: 1139 QYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE--QEKRRQERE 1196
Q E E V E+ + E R + E E +E+E + +L +E Q +R +E+
Sbjct: 1795 QRAEAERVLAEKLAAIGEAT--RLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQA 1852
Query: 1197 RQYREE-EELQRQKRK----QRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFR 1251
Q++ + EE Q RK + R + D Q +E + + K +
Sbjct: 1853 AQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAEL 1912
Query: 1252 QLEDSQLRDR-----QSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE 1306
+LE ++R +S++ + Q++ E+ERRR + +R ++ L EE E
Sbjct: 1913 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER---VQKSLAAEE--E 1967
Query: 1307 AKRRDRKSQEEKQLLREEREEKRR-RQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365
A R+ + + EE + L+ + EE RR R+ +++ + QL QE ++ L+ +E+ F +
Sbjct: 1968 AARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ 2027
Query: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425
+ + Q + L++EQ + Q R + E R E ++ R +R+ + +Q+
Sbjct: 2028 QKEQELQ--QTLQQEQSVLDQLRG----EAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2081
Query: 1426 QERDRKFREEEQQVR--------------RQERERKFLEEEQQLRQ--------ERHRKF 1463
ER ++ EE+ Q R QE R+ E+ LRQ E+H+KF
Sbjct: 2082 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2141
Query: 1464 REEEQLLQEREEQ-------QLHRQERDRKFLEEEQQLRRQE-----RDRKFREQELRSQ 1511
E+ + + EQ QL + + L+EE Q + E R R E+EL S
Sbjct: 2142 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2201
Query: 1512 EPERKFLEEEQQLHRQQRQRKFLQEEQQLRR--QERGQQRRQDRDRKFR------EEEQL 1563
+ + L + + + + L+++ +R QE ++ +Q + R E +L
Sbjct: 2202 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2261
Query: 1564 RQEREE---QQLSRQERDRKFR----------------LEEQKVRRQEQERKFMEDEQQL 1604
RQ EE QQ + E+ K + L++QK QEQ R+ ED++Q+
Sbjct: 2262 RQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQM 2321
Query: 1605 RRQEGQQQLRQERDRKFREDEQLLQEREEQQLH----RQERDRKFLEEEPQLRRQEREQ- 1659
+Q ++ +R + QL E ++L R + EE+ Q R++ E+
Sbjct: 2322 AQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2381
Query: 1660 -QLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQ---Q 1715
+ H + +E+ L+Q E ++RQ+ D + + ERE++ LQ+E Q
Sbjct: 2382 GEKLHRTELATQEKVTLVQTLE---IQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2438
Query: 1716 LRRQELERKFREEEQLRQET---------EQEQLRRQERYRKILEEEQLRPE---REEQQ 1763
L+ +E++ ++EQL QET E++ L ++ER+ +E+E+ + E ++E
Sbjct: 2439 LKSEEMQTV--QQEQLLQETQALQQSFLSEKDSLLQRERF---IEQEKAKLEQLFQDEVA 2493
Query: 1764 LRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE-EEQLRQEREE-QQLRPQQRDGKY 1821
+Q R+ + R+++Q+ QER+ +E+ R+ E EE +R+++EE QQL Q+R +
Sbjct: 2494 KAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEE 2553
Query: 1822 RWEEEQLQLEEQEQRL-RQERDRQYRAEEQFATQEKSRR-------------EEQELWQE 1867
EE +L EQ Q L Q R +EE A+Q + + E E
Sbjct: 2554 LLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHS 2613
Query: 1868 EEQKRRQERERKLREEHI---RRQQKEEQRHRQVGEIKSQEGKGH 1909
+ RR+ ++L+E I Q+ Q H V E+ +E H
Sbjct: 2614 FDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRH 2658
Score = 321 bits (822), Expect = 5e-87
Identities = 452/1778 (25%), Positives = 777/1778 (43%), Gaps = 303/1778 (17%)
Query: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ--LRREQQL-----------RR 421
Q LRR+ QL R L + L+ E+Q + L Q LR Q R
Sbjct: 865 QSLRRDVQLIRSWSLATFRTLKPEEQRQALHSLELHYQAFLRDSQDAGGFGPEDRLMAER 924
Query: 422 E------------QQLRREQEEERHEQKHEQERREQRLKREQEERRDW----LKREEETE 465
E Q L + +EE Q+ E ++ RL+ E E R L ++E
Sbjct: 925 EYGSCSHHYQQLLQSLEQGAQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPA 984
Query: 466 RHEQERRKQQLKRDQEEE-----------RRERWLKLEEEERREQQERREQQLRREQ-EE 513
R +R +Q K E E E+ L L E R E +L + E+
Sbjct: 985 RECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQ 1044
Query: 514 RREQRLKRQEEEERLQQRLR----SEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
R E+ + + +R +E+ LR +E+ +E LE + + R
Sbjct: 1045 VRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLR 1104
Query: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER 629
Q E + + R + R +E ERL+QR +VE ER Q L ER
Sbjct: 1105 AQAEAQQPTF--DALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLL-------ER 1155
Query: 630 RQQLLKSEEQEERRQQQLRREQQERRE---------QRLKREEEE---------ERLEQR 671
Q +L + +R +QL R+ + RE Q +R +E+ + + ++
Sbjct: 1156 WQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQ 1215
Query: 672 LKREH---EEERREQELAEEEQEQARERIKS------RIPKWQWQLESEADARQSKVYSR 722
L++E EE R E EE Q A++ I + ++ ++ QLE A + +
Sbjct: 1216 LRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK-----K 1270
Query: 723 PRKQEGQRRRQEQEEKRRRRESEL----------------QWQEEERAHRQQQEEEQRRD 766
P+ Q G ++ R SEL + +EEER QQ+ EE+ R
Sbjct: 1271 PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER- 1329
Query: 767 FTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQR-EQRFLPEEEEKEQRRRQRR 825
+ E E+ RQ A + Q ER+ A+E QQR ++ + EE ++Q+R
Sbjct: 1330 ---LAEVEAALEKQRQLAEAHAQAKAQAERE--AKELQQRMQEEVVRREEAAVDAQQQKR 1384
Query: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR 885
++ELQ L + + + + +A+Q + E + R R +E+ R R QLE ++R
Sbjct: 1385 SIQEELQQLRQSSEAEIQAKARQAEAAE------RSRLRIEEEIRVV--RLQLEATERQR 1436
Query: 886 ---RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQER------------QY 930
L A A E+ +++ QEE E L+R+ +++ +R+ Q
Sbjct: 1437 GGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAA 1496
Query: 931 REEEQLQQ--EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK 988
RE+++ Q EE +L EE E+R RQ + R+ + + ++ E + +R EK
Sbjct: 1497 REKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEK 1556
Query: 989 KYREEEELQQEEEQL--LREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
+ E LQ+E + LREE E+R +Q+ E + R ++E ++E E+ + E RL+ +
Sbjct: 1557 TAQLERSLQEEHVAVAQLREEAERRAQQQAEAE-RAREEAERELERWQLKANEALRLRLQ 1615
Query: 1047 ERQYREEEELQQEEEQLLGEE--RETRRRQELERQYRKEEELQQEE----EQLLREEPEK 1100
+ +++ L Q E + EE RE RRR + E Q ++ EL ++E QL ++
Sbjct: 1616 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1675
Query: 1101 RRRQERER-QCREEEELQQEEEQLLREEREK---------RRRQELERQYREEEEVQQEE 1150
R E+E + R E E +++ QLL EE + ++RQELE E +V+ E
Sbjct: 1676 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA---ELAKVRAEM 1732
Query: 1151 EQLL----REEPEKRRRQELERQYREEE-----ELQQEEEQLLREEQEKRRQERERQYRE 1201
E LL R E E R E +Q E E EL +E +L +E +RQ RQ E
Sbjct: 1733 EVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ---RQLAE 1789
Query: 1202 EEELQRQKRKQRYRDEDQRS-DLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQL-- 1258
E+ +++ +R E + + + E E A+++ K ENE+ R+L + +
Sbjct: 1790 EDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKE-----KEAENERLRRLAEDEAFQ 1844
Query: 1259 RDRQSQQDLQH-------LLGEQQERDREQERRRWQQRD----RHFPEEEQLEREEQKEA 1307
R R +Q QH L ++ D E ER++ D R EEE L + E
Sbjct: 1845 RRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEK 1904
Query: 1308 KR-----------RDRKSQEEKQLLREEREEKRRRQ-----ETDRKFREEEQLLQEREEQ 1351
R R + E+ +E+ E + RQ E +R+ RE E ER ++
Sbjct: 1905 AAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE----ERVQK 1960
Query: 1352 PLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR-------------QERERKFLKEEQQ 1398
L +E + R+ L E+ + +EE +RLR QE +K L+ E++
Sbjct: 1961 SLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEK 2020
Query: 1399 LRC---QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ-ERE----RKFLE 1450
Q++EQ+L+Q ++ +Q E R+ EE ++ R Q ERE R+ +E
Sbjct: 2021 AHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2080
Query: 1451 EEQQLRQERHRKFREE-------EQLLQEREEQQLHRQERDRKFLEEEQQLRRQ-ERDRK 1502
E ++L+Q + + E+L +E E++ R + ++ L ++Q + E+ +K
Sbjct: 2081 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2140
Query: 1503 FREQELRSQ-EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561
F EQ LR + + E++ QL Q+ L EE Q + E + RQ R EEE
Sbjct: 2141 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQ---RSQVEEE 2197
Query: 1562 QLRQEREEQQLSRQERDRKFRLEEQK----VRRQEQERKFMEDEQQLRRQEGQQQLRQER 1617
+ ++LS+ K R+E + +R ++ ++F+++E + +Q ++ R
Sbjct: 2198 LFSVRVQMEELSKL----KARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV 2253
Query: 1618 DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQ 1677
+ E +L Q EE ++ K L+E+ Q ++ + + E +LLQ
Sbjct: 2254 AAQ--EAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT----------RLKAEAELLQ 2301
Query: 1678 EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ 1737
+ +E QE+ R+ +E+++Q+ +Q L EE Q ++ LE + + + ++ E E+
Sbjct: 2302 QQKELA---QEQARRLQEDKEQMAQQ------LAEETQGFQRTLEAERQRQLEMSAEAER 2352
Query: 1738 EQLRRQERYRKILEEEQLRPEREEQQLRRQERD--RKFREEEQLRQER----EEQQLRSQ 1791
+LR E R Q R E + Q+ R+Q + K E QE+ + +++ Q
Sbjct: 2353 LKLRVAEMSRA-----QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2407
Query: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYR----- 1846
+SD + E E ++ + QQ + + E++Q +QEQ L++ + Q
Sbjct: 2408 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2467
Query: 1847 ----AEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIK 1902
E+F QEK++ E+ L+Q+E K +Q RE + +RQQ++ ++ RQ
Sbjct: 2468 DSLLQRERFIEQEKAKLEQ--LFQDEVAKAQQLREEQ------QRQQQQMEQERQRLVAS 2519
Query: 1903 SQEGKGHGRLLEPGTHQFASVPVRSSPLYEYIQEQRSQ 1940
+E + E G + + L + Q++R Q
Sbjct: 2520 MEEARRRQHEAEEGVRR------KQEELQQLEQQRRQQ 2551
Score = 311 bits (798), Expect = 3e-84
Identities = 324/1270 (25%), Positives = 597/1270 (47%), Gaps = 197/1270 (15%)
Query: 98 EKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE- 156
+ +A+ + + LQ R QEE RR + ++ + +R Q+ +Q R+ +E E Q++
Sbjct: 1349 QAKAQAEREAKELQQRMQEEVVRR---EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKA 1405
Query: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERR-AEEEQLQSCKGHETEEFPDEEQLRRREL 215
+Q +R R R +EE+ R + + E +R E +LQ+ + EE +++ + E
Sbjct: 1406 RQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRA-RAEEAEAQKRQAQEEA 1464
Query: 216 LELRRKGREEKQQQRR---ERQDRVFQEEEEKEWRKRETVLRKE--------EEKLQEEE 264
LRR+ ++E Q++R+ E RV E E ++R +E E +L++ E
Sbjct: 1465 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1524
Query: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
+R R++Q E ++ EL+ +R ++ +L R Q + RE+ E R +Q
Sbjct: 1525 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1584
Query: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
Q E+ E E++L R Q + E R Q EE +Q+ + E E+++++ RE + R
Sbjct: 1585 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1644
Query: 385 ---REQQLRR----EQQLRREQQLRR---EQQLRREQQLRR----------EQQLRREQQ 424
EQ +R+ EQ+L +++QL +Q+L EQ+L R ++QL E+
Sbjct: 1645 GKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEEL 1704
Query: 425 LRREQEEERHEQKHEQ-ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD---- 479
R ++E QK ++ E +++ E E R EE R E+ KQ+L+ +
Sbjct: 1705 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1764
Query: 480 -------------QEEERRERWLKLEEEERREQQERR-----------------EQQLRR 509
EE +R+R L E+ R+ + R E ++
Sbjct: 1765 RELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL 1824
Query: 510 EQEERREQRLKRQEEEERLQQRLRSEQ--QLRREQEERREQLLKR-----EEEKRLEQER 562
+++E +RL+R E+E Q+R EQ Q + + EER QL K E +K L ++
Sbjct: 1825 KEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDT 1884
Query: 563 REQRLKREQE---------------------------ERRDQLLKREEER---------- 585
QR + E+E D L +E+
Sbjct: 1885 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1944
Query: 586 -RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
++R +RE EER+++ L EE E Q + + ++R + + E ++L + EQE RQ
Sbjct: 1945 AEEERRRREAEERVQKSLAAEE-EAARQRKAALEEVERLKAKVEEARRLRERAEQESARQ 2003
Query: 645 QQLRREQQERREQRLKR------EEEEERLEQRLKREH---EEERREQELAE---EEQEQ 692
QL +E ++R Q ++ +++E+ L+Q L++E ++ R E E A EE E+
Sbjct: 2004 LQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2063
Query: 693 ARERIKSRIPKWQWQLESEADARQS---KVYSRPRKQ---EGQRRRQEQEEKRRRRESEL 746
AR + + + + Q+E +QS + +R + Q E R+ EQE RR + +
Sbjct: 2064 ARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQA 2123
Query: 747 QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA-----RPPLREQRERQLRAE 801
++++ A + ++ ++ + T + +A+ + E RL + L ++ ++L+AE
Sbjct: 2124 ALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2183
Query: 802 ERQQREQRFLPEEE--------EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
+ QR EEE E+ + + R E E L +++ QR LQEE
Sbjct: 2184 ATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR-----FLQEEA 2238
Query: 854 DGLQE--DQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEE 911
+ +++ ++ R S + + R EE+ ++R AL E++ KE+ +E
Sbjct: 2239 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQR-------ALAEKMLKEKMQAVQEAT 2291
Query: 912 ELQRE----EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967
L+ E +++K QEQ R+ +E++ +Q +QL E + +R E ERQ + + +
Sbjct: 2292 RLKAEAELLQQQKELAQEQARRLQEDK--EQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2349
Query: 968 QKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR----QEWERQYRKK 1023
+ +L E + + + E R ++ ++ E+L R E + + Q E Q ++
Sbjct: 2350 AERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2409
Query: 1024 D-ELQQEEEQLLREEREKRRLQERER--QYREEEELQQEEEQLLGEERETRRR--QELER 1078
D + ++ E + EREK +LQ+ + Q + EE ++EQLL E + ++ E +
Sbjct: 2410 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDS 2469
Query: 1079 QYRKEEELQQEE---EQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135
++E ++QE+ EQL ++E K +Q RE Q R++++++QE ++L+ E RR
Sbjct: 2470 LLQRERFIEQEKAKLEQLFQDEVAK-AQQLREEQQRQQQQMEQERQRLVASMEEARR--- 2525
Query: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
RQ+ EE V++++E+L Q+LE+Q R++EEL EE Q LRE+ + ++
Sbjct: 2526 --RQHEAEEGVRRKQEEL----------QQLEQQRRQQEELLAEENQRLREQLQLLEEQH 2573
Query: 1196 ERQYREEEEL 1205
EE+
Sbjct: 2574 RAALAHSEEV 2583
Score = 212 bits (539), Expect = 3e-54
Identities = 221/808 (27%), Positives = 387/808 (47%), Gaps = 87/808 (10%)
Query: 88 ALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRR--QKRQEQE 145
A+G+AT L E KE+ + R+ + F+ R+LEE+ Q + ++R Q
Sbjct: 1809 AIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQ--RRRLEEQAAQHKADIEERLAQL 1866
Query: 146 RELAEGEEQSEKQERLEQRDRQRR--DEELWRQRQEWQEREERRAE-EEQLQSCKGHETE 202
R+ ++ E + +K +E RQRR +EE+ + +++ +AE E +L + +
Sbjct: 1867 RKASDSELERQK-GLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA-- 1923
Query: 203 EFPDEEQLRRRELLEL----RRKGREEKQQQRRERQDRVFQE--EEEKEWRKRETVLRKE 256
E+ LR +E EL +R+ E++++RRE ++RV + EE+ R+R+ L +
Sbjct: 1924 ----EDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 1979
Query: 257 EE-KLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL---RREQQLRRKQEE 312
E K + EE +R RE E+E + QE ++R + E++ ++EQ+L++ ++
Sbjct: 1980 ERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQ 2039
Query: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER 372
E+ + R E + R EE E R Q ER Q RR+ EE R +Q EQ + R
Sbjct: 2040 EQSVLDQLRGEAEAARRAAEEAEE---ARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2096
Query: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLR----------REQQLRREQQLRRE 422
+ Q E +LR+E + ++ + EQ R++Q EQ LR++ Q+ +E
Sbjct: 2097 AQAQAAAE-KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQE 2155
Query: 423 QQLRREQEEERHEQKHEQERREQRLKREQEE---RRDWLKREEETERHEQERRKQQLKRD 479
R Q EE QK+ + QRLK E E +R ++ E + R + E + R
Sbjct: 2156 LTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2215
Query: 480 QEEER------RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
+ E R ++ + +EE + ++ E+ R + RL++ EE+ QQR
Sbjct: 2216 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2275
Query: 534 SEQQLRREQEERRE--------QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585
+E+ L+ + + +E +LL++++E EQ RR Q E +E+ Q L E +
Sbjct: 2276 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ----EDKEQMAQQLAEETQG 2331
Query: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ 645
Q+ L+ E++ +LE + E ++ E R Q E+ + R+Q E E+ +
Sbjct: 2332 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ---AEEIGEKLHRT 2388
Query: 646 QLRREQQERREQRLK-REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKW 704
+L +++ Q L+ + ++ + +RL+ E RE+E ++E + + + +
Sbjct: 2389 ELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQ 2448
Query: 705 QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR 764
Q QL E A Q S + R EQE+ + Q ++E A QQ EEQ+
Sbjct: 2449 QEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE-----QLFQDEVAKAQQLREEQQ 2503
Query: 765 RDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQR 824
R +++ E+ RQRL A + E R RQ AEE +R+Q EE +Q +QR
Sbjct: 2504 RQ-------QQQMEQERQRLVA--SMEEARRRQHEAEEGVRRKQ------EELQQLEQQR 2548
Query: 825 REREKELQFLEEEEQLQRRERAQQLQEE 852
R++E+ L EE + RE+ Q L+E+
Sbjct: 2549 RQQEE----LLAEENQRLREQLQLLEEQ 2572
Score = 151 bits (382), Expect = 5e-36
Identities = 162/632 (25%), Positives = 294/632 (46%), Gaps = 80/632 (12%)
Query: 99 KRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQ-----------ERE 147
+RA + +E+ +Q R+ RR Q+EE +R +Q +EQ E+
Sbjct: 2055 RRAAEEAEEARVQAEREAAQSRR------QVEE--AERLKQSAEEQAQARAQAQAAAEKL 2106
Query: 148 LAEGEEQSEKQERLEQ---RDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
E E+++ ++ + EQ R +Q D E+ + ++ ++ ++A+ EQ + + EE
Sbjct: 2107 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2166
Query: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQD----RVFQEEEEK-----EWRKRETVLRK 255
++ L EL L+ + E +Q+ + ++ RV EE K E R +LR
Sbjct: 2167 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD 2226
Query: 256 EE--EKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ--EEEQQQQRLRREQQLRRK-- 309
++ ++ +EE ++ +++ EE +L + QE R RQ EE+ QQR E+ L+ K
Sbjct: 2227 KDNTQRFLQEEAEKMKQVAEEAARL-SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQ 2285
Query: 310 --QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE------EERRE 361
QE R + + E +QQ+ Q++ RR Q E +E+ QQL E + E R+
Sbjct: 2286 AVQEATRLKAEAELLQQQKELAQEQARRLQ----EDKEQMAQQLAEETQGFQRTLEAERQ 2341
Query: 362 QQLRREQEEER---REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
+QL E ER R ++ R Q E R +Q + +L ++++ Q
Sbjct: 2342 RQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT 2401
Query: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR 478
L ++Q E E E ER +++L Q+E + + EE + +QE+ Q+ +
Sbjct: 2402 LEIQRQQSDHDAERLREAIAELEREKEKL---QQEAKLLQLKSEEMQTVQQEQLLQETQA 2458
Query: 479 DQEEERRERWLKLEEEERREQQERREQQL-----RREQEERREQRLKRQEEEERLQQRLR 533
Q+ E+ L+ E EQ++ + +QL + Q+ R EQ+ ++Q+ E+ Q+ +
Sbjct: 2459 LQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVA 2518
Query: 534 SEQQLRREQEERREQLLKREEE-KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592
S ++ RR Q E E + +++EE ++LEQ+RR+Q ++LL E +R +++L+
Sbjct: 2519 SMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ----------EELLAEENQRLREQLQL 2568
Query: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRRE-- 650
+E+ EEV + + R+ + +E + E LRR+
Sbjct: 2569 LEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGP------AAEAEPEHSFDGLRRKVS 2622
Query: 651 QQERREQRLKREEEEERLEQRLKREHEEERRE 682
Q +E + EE +RL Q E RRE
Sbjct: 2623 AQRLQEAGILSAEELQRLAQGHTTVDELARRE 2654
Score = 96.3 bits (238), Expect = 3e-19
Identities = 86/335 (25%), Positives = 166/335 (49%), Gaps = 42/335 (12%)
Query: 80 KVAQACYYALGQATGLDEEKRARCDGKESLLQDRR------QEEDQRRFEPRDRQLEEEP 133
K+ Q A + E R R +E L Q R +E+ Q E + E E
Sbjct: 2240 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAEL 2299
Query: 134 GQRRRQKRQEQERELAEGEEQSEKQ--------ERLEQRDRQRRDE-----ELWRQRQEW 180
Q++++ QEQ R L E +EQ +Q +R + +RQR+ E E + R
Sbjct: 2300 LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAE 2359
Query: 181 QEREERRAEEEQLQSCKGHET-------EEFPDEEQLRRRELLELRRKGREEKQQQRRE- 232
R + RAEE+ + K E E +E++ + LE++R+ + ++ RE
Sbjct: 2360 MSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREA 2419
Query: 233 ------RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRK---LER 283
++++ QE + + + E ++E+ LQE + +Q L E++ L++ +E+
Sbjct: 2420 IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQ 2479
Query: 284 QELRRER--QEEEQQQQRLRREQQLRRKQEEERREQ----QEERREQQERREQQEERREQ 337
++ + E+ Q+E + Q+LR EQQ +++Q E+ R++ EE R +Q E+ R+++
Sbjct: 2480 EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQE 2539
Query: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEER 372
+L++ +++RR+Q+ +E +R +QL+ +E+ R
Sbjct: 2540 ELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHR 2574
Score = 37.4 bits (85), Expect = 0.14
Identities = 73/313 (23%), Positives = 122/313 (38%), Gaps = 57/313 (18%)
Query: 933 EEQLQQEEEQLLREEREKRRRQER----ERQYRKDKKLQQKEEQLL--GEEPEKRRRQER 986
E+QL+ E E+L +R + Q E Q + L Q + +LL G+ P++ ER
Sbjct: 349 EKQLRSEFERLECLQRIVTKLQMEAGLCEEQLNQADALLQSDVRLLAAGKVPQRAGEVER 408
Query: 987 E-KKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ-EEEQLLR--------- 1035
+ K L + Q L++ R + Q + R YR + L E LR
Sbjct: 409 DLDKADSMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPA 468
Query: 1036 EEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE----------LERQYRKEEE 1085
+ + LQ +R+ E+ + + LL E + R + +E Q
Sbjct: 469 TQVAQVTLQSVQRRPELEDSTLRYLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRG 528
Query: 1086 LQQEEEQLLREEPEKRRRQERE---------RQCREEEELQQEEEQLLREEREKRRRQEL 1136
L Q E+ R + E+ R E + R C +LQ + LL + + R E
Sbjct: 529 LHQSIEEF-RAKIERARSDEGQLSPATRGAYRDCLGRLDLQYAK--LLNSSKARLRSLES 585
Query: 1137 ERQY-------------REEEEV-----QQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178
+ +EEEEV + ++E +ELE + ++ +ELQ
Sbjct: 586 LHSFVAAATKELMWLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQN 645
Query: 1179 EEEQLLREEQEKR 1191
++LLRE+ R
Sbjct: 646 AGDRLLREDHPAR 658
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 342 bits (876), Expect = 3e-93
Identities = 446/1785 (24%), Positives = 774/1785 (43%), Gaps = 216/1785 (12%)
Query: 114 RQEEDQRRFEPRDRQL-EEEPG----------QRRRQKRQEQER------ELAEGEEQSE 156
R +D F P DR + E E G Q Q QE+ R EL + Q E
Sbjct: 1075 RDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGAQEESRCQRCISELKDIRLQLE 1134
Query: 157 KQE-RLEQRDRQRRDEELWRQ-RQEWQEREERRAEEEQL------QSCKGHETEEFPDEE 208
E R R R D+E R+ Q E+++ +AE E L S + + P+
Sbjct: 1135 ACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPS 1194
Query: 209 QL--RRRELLELRRKGREEKQQQRRERQDRVFQEEEE------KEWRKRETVLRKEEEKL 260
R LEL E+ + ++ E+ + + + E VLR EE+L
Sbjct: 1195 PAAPTLRSELELTLGKLEQVRS-----LSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQL 1249
Query: 261 QEEE--PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318
+E + P EL+ + L+KL R + ++ + + LR Q++ + ++ E+
Sbjct: 1250 KEAQAVPATLPELEATKASLKKL-RAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERD 1308
Query: 319 EERREQQERREQQEERREQQLRREQEERRE-QQLRREQEEERRE-QQLRREQEEERREQQ 376
E +ER Q ER + L + +RE +QL R+ R L ++ RR Q+
Sbjct: 1309 VEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQE 1368
Query: 377 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE---- 432
+ L Q +R +QLR+EQ L E + R + E Q +Q + ++ E
Sbjct: 1369 QIQAMPLADSQAVR--EQLRQEQALLEE--IERHGEKVEECQRFAKQYINAIKDYELQLV 1424
Query: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR----------KQQLKRDQEE 482
++ + E + + Q ++ + H E + L+R +EE
Sbjct: 1425 TYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEE 1484
Query: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
ER + EE ER + E ++ R+ E + + + + E + LQQR++ E+ +RRE+
Sbjct: 1485 ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ-EEVVRREE 1543
Query: 543 EERREQLLKREEEKRLEQERRE-----QRLKREQEERRDQLLKREEERRQQRLKREQEER 597
Q KR ++ L+Q R+ Q R+ E L+ EEE R RL+ E ER
Sbjct: 1544 AAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATER 1603
Query: 598 -----------LEQRLKREEVERLEQEERREQRLKREEPEEERRQQ----LLKSEEQEER 642
L R + E ++ + +E E+ ++ + E +R++Q L + E
Sbjct: 1604 QRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAE 1663
Query: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIP 702
++ +R Q E RL+ EE E RL Q E E R+ Q E Q A ++S+
Sbjct: 1664 AAREKQRALQALEELRLQAEEAERRLRQ---AEVERARQVQVALETAQRSAEAELQSKRA 1720
Query: 703 KW-QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES---ELQ-WQ---EEERA 754
+ + + E ++ V ++E +RR Q+Q E R RE EL+ WQ E
Sbjct: 1721 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1780
Query: 755 HRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE- 813
R Q EE ++ Q +AE++ E + R EQ RQ E++ +QR L E
Sbjct: 1781 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEG 1840
Query: 814 --------EEEKEQRRRQRREREKELQFLEEE-EQLQRR-----ERAQQLQEEEDGLQED 859
E+E + R + + E++ Q LEEE +LQR ++ Q+L+ E ++ +
Sbjct: 1841 TAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAE 1900
Query: 860 QE-----RRRSQEQRR--DQKWRWQLEEERKRRRHTLYAKP---ALQEQLRKEQQLLQEE 909
E + R++E+ R +K + +LE E R R AL E+ ++++Q L EE
Sbjct: 1901 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQ-LAEE 1959
Query: 910 EEELQREEREK-------------RRRQEQERQYREEEQLQQEEEQLLREEREKRRR--- 953
+ QR E E+ R + E E +E+E + +L +E +RRR
Sbjct: 1960 DAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEE 2019
Query: 954 ---------QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
+ER Q RK + + ++ L E+ ++RRQ E+ + ++
Sbjct: 2020 QAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKA 2079
Query: 1005 REEREKRR-RQEWERQYRKKD--ELQQEEEQLLREEREKRRLQERERQYR----EEEELQ 1057
E E R R E R K+ EL+ ++ L E E+RR + ER + EEE +
Sbjct: 2080 ELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR 2139
Query: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117
Q + L ER + +E R + E+ + QL +E +KR + E + ++ +
Sbjct: 2140 QRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 2199
Query: 1118 QEEEQLLREERE--KRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175
QE +Q L++E+ + R E E R EE ++ Q RE + R RQ E E
Sbjct: 2200 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR------RQVEEAER 2253
Query: 1176 LQQE-EEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234
L+Q EEQ Q + E+ R+ E+E +R + +Q + Q +D E EK
Sbjct: 2254 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADA----EMEKHKK 2309
Query: 1235 VRDNKVYCKGRENEQFR----QLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRD 1290
+ + K + ++ QLE++ + ++LQ L E E R++ + +
Sbjct: 2310 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2369
Query: 1291 RHFPEEEQLEREEQKEAKRRD---RKSQEEKQLLREEREEKRRRQETDRKF----REEEQ 1343
EE + + + EA+ R R ++ L+EE E+ ++ E + +E +
Sbjct: 2370 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2429
Query: 1344 LLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQE 1403
L Q EE +++ K +E+++ ++ + E + L++Q K L +EQ R QE
Sbjct: 2430 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQ----KELAQEQARRLQE 2485
Query: 1404 REQQLRQDRDRKF----------REEEQQLSRQERDRKFREEEQ---QVRRQERERKFLE 1450
++Q+ Q + R+ + ++S + K R E Q R +E ++F +
Sbjct: 2486 DKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRK 2545
Query: 1451 EEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE--- 1507
+ +++ ++ HR ++ + + ++ RQ+ D + + ER+++ +QE
Sbjct: 2546 QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKL 2605
Query: 1508 LRSQEPERKFLEEEQQLHRQQR-QRKFLQEEQQLRRQERG-QQRRQDRDRKFREE----E 1561
L+ + E + +++EQ L Q Q+ FL E+ L ++ER +Q + ++ F++E +
Sbjct: 2606 LQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQ 2665
Query: 1562 QLRQERE-EQQLSRQERDRKFRLEEQKVRRQ----EQERKFMEDEQQLRRQEGQQ-QLRQ 1615
QLR+E++ +QQ QER R E+ RRQ E R+ E+ QQL +Q QQ +L
Sbjct: 2666 QLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLA 2725
Query: 1616 ERDRKFREDEQLLQEREEQQLHRQER--------DRKFLEEEPQLRRQEREQQLRHDRDR 1667
E +++ RE QLL+E+ L E + L E + H D
Sbjct: 2726 EENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDG 2785
Query: 1668 KFRE-EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ 1711
R+ Q LQE +R + +L R+E R +LQ
Sbjct: 2786 LRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQ 2830
Score = 326 bits (836), Expect = 1e-88
Identities = 360/1355 (26%), Positives = 617/1355 (45%), Gaps = 193/1355 (14%)
Query: 113 RRQEEDQR-----RFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQ 167
RR EE++R R E R+R E E E++R+LAE Q++ Q E ++ Q
Sbjct: 1479 RRMEEEERLAEQQRAEERERLAEVEAA-------LEKQRQLAEAHAQAKAQAEREAKELQ 1531
Query: 168 RR--DEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE- 224
+R +E + R+ ++++R+ +E+LQ QLR+ E++ K R+
Sbjct: 1532 QRMQEEVVRREEAAVDAQQQKRSIQEELQ--------------QLRQSSEAEIQAKARQA 1577
Query: 225 ---EKQQQRRERQDRVFQEEEEKEWRKR---ETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
E+ + R E + RV + + E R+R E L+ + +E E Q+ R+ QEE E+L
Sbjct: 1578 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK-RQAQEEAERL 1636
Query: 279 RKLERQELRRERQEEEQQQQRLRREQQLRRKQE------EERREQQEERREQQERREQQE 332
R+ + E +R+RQ E + R++ E + R+++ EE R Q EE E++ R+ + E
Sbjct: 1637 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE-AERRLRQAEVE 1695
Query: 333 ERREQQLRREQEER---REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
R+ Q+ E +R E Q +R E+ Q R QEE QLR E + R +QQ
Sbjct: 1696 RARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQA 1755
Query: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
E+ ++ QL+ + LR Q Q + + E +QK E ER +R +
Sbjct: 1756 EAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGK 1815
Query: 450 EQEE---RRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506
+E+ +R+ ++E E +R E QQ ++E R L+ E E+ +Q++ E++
Sbjct: 1816 AEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR---LRAETEQGEQQRQLLEEE 1872
Query: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566
L R Q E KRQE E L ++R E E + EEE R E+ +QR
Sbjct: 1873 LARLQREAAAATQKRQELEAEL-------AKVRAEMEVLLASKARAEEESRSTSEKSKQR 1925
Query: 567 LKRE------------------QEERRDQLLKREEERRQQ------------------RL 590
L+ E +E +R + L E+ RQ+ RL
Sbjct: 1926 LEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRL 1985
Query: 591 KREQEERL-EQRLKREEVERLEQEERREQRLKREEPE------EERRQQLLKSEEQEERR 643
K E E L E+ + E + RL ++E ++R E+ EER QL K+ + E R
Sbjct: 1986 KTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELER 2045
Query: 644 QQQL------RREQQERREQRLK--------------------REEEEERLEQRLKREHE 677
Q+ L +R Q E LK R E+ L + + E E
Sbjct: 2046 QKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELE 2105
Query: 678 EERREQELAEEE--QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQ 735
R+ Q AEEE + +A ER++ + + + + A +V K E RR +E+
Sbjct: 2106 AARQRQLAAEEERRRREAEERVQKSLAA-EEEAARQRKAALEEVERLKAKVEEARRLRER 2164
Query: 736 EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRE 795
E+ R+ +L +E A ++ Q EE+ F Q + +E + +Q S LR + E
Sbjct: 2165 AEQESARQLQL---AQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2221
Query: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDG 855
RA E + E+ + E E Q RRQ E E+ Q EEQ Q R +AQ E+
Sbjct: 2222 AARRAAE--EAEEARVQAEREAAQSRRQVEEAERLKQ--SAEEQAQARAQAQAAAEKLRK 2277
Query: 856 LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL----LQEEEE 911
E + RR+Q ++ + + + E + +H +A+ L+++ + EQ+L LQ EE
Sbjct: 2278 EAEQEAARRAQAEQAALRQKQAADAEME--KHKKFAEQTLRQKAQVEQELTTLRLQLEET 2335
Query: 912 ELQR---EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
+ Q+ +E +R + E R+ Q+++E + + E + + R + L+
Sbjct: 2336 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD 2395
Query: 969 KE--EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
K+ ++ L EE EK ++ E + + L EE ++R E+ ++K +
Sbjct: 2396 KDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQA 2455
Query: 1027 QQEEEQLLRE----EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK 1082
QE +L E +++K QE+ R+ +E++E Q +QL E + +R E ERQ +
Sbjct: 2456 VQEATRLKAEAELLQQQKELAQEQARRLQEDKE--QMAQQLAEETQGFQRTLEAERQ--R 2511
Query: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYRE 1142
+ E+ E E+L E R Q R EE+ Q+ +Q E EK R EL Q +
Sbjct: 2512 QLEMSAEAERLKLRVAEMSR-----AQARAEEDAQRFRKQ-AEEIGEKLHRTELATQEKV 2565
Query: 1143 EEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREE 1202
E ++ + +R R+ + RE+E+LQQE + L + +E + ++E+ +E
Sbjct: 2566 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQET 2625
Query: 1203 EELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQ 1262
+ LQ Q + E + S L+ + E+E A + + + +Q R E+ Q + +Q
Sbjct: 2626 QALQ-----QSFLSE-KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR--EEQQRQQQQ 2677
Query: 1263 SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR 1322
+Q+ Q L+ +E R Q E E+ R +Q+E ++ +++ +++++LL
Sbjct: 2678 MEQERQRLVASMEEARRRQH------------EAEEGVRRKQEELQQLEQQRRQQEELLA 2725
Query: 1323 EEREEKRRRQETDRKFREEEQLLQEREEQPLRRQE 1357
EE +++ RE+ QLL+E+ L E
Sbjct: 2726 EE----------NQRLREQLQLLEEQHRAALAHSE 2750
Score = 324 bits (830), Expect = 6e-88
Identities = 461/1845 (24%), Positives = 811/1845 (43%), Gaps = 259/1845 (14%)
Query: 253 LRKEEEK--LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQ 310
L+ EE++ L E Q L++ ++ L ER+ + Q L +
Sbjct: 1054 LKPEEQRQALHSLELHYQAFLRDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGA 1113
Query: 311 EEERREQQ--EERREQQERREQQEERREQQLR--------REQEERREQQLRREQEEERR 360
+EE R Q+ E ++ + + E E R +LR RE +R +Q + + E E
Sbjct: 1114 QEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGL 1173
Query: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
+ + R E E+ L + LR E +L L + +Q+R + E+
Sbjct: 1174 GKGVARLSAEA--EKVLALPEPSPAAPTLRSELELT----LGKLEQVRSLSAIYLEKLKT 1227
Query: 421 REQQLRREQEEERHEQKHEQERREQRLKR----EQEERRDWLKR---EEETERHEQERRK 473
+R Q E + HE++ +E + E E + LK+ + E ++ + +
Sbjct: 1228 ISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALR 1287
Query: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
+L+ QE R + E + E+ R QL + Q RQ E E+L ++LR
Sbjct: 1288 DELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLR 1347
Query: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE 593
+ E + L ++ R QE+ + + + R+QL R+E+ + ++R
Sbjct: 1348 YYR-------ESADPLGAWLQDARRRQEQIQAMPLADSQAVREQL--RQEQALLEEIERH 1398
Query: 594 QEERLE-QRLKREEVERLEQEERREQRLKRE-EP--EEERRQQLLKSEEQEERRQQQLRR 649
E+ E QR ++ + ++ E + K + EP ++ ++ E + LR
Sbjct: 1399 GEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRT 1458
Query: 650 EQQERR----------EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
E + L+R EEEERL ++ + E E E E A E+Q Q
Sbjct: 1459 HYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQL------ 1512
Query: 700 RIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQ- 758
+EA A+ R K+ QR QEE RR E+ + Q+++R+ +++
Sbjct: 1513 ----------AEAHAQAKAQAEREAKELQQRM---QEEVVRREEAAVDAQQQKRSIQEEL 1559
Query: 759 QEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQ-----REQRFLPE 813
Q+ Q + Q +A + R RL +R R QL A ERQ+ Q
Sbjct: 1560 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVR-LQLEATERQRGGAEGELQALRAR 1618
Query: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRR----ERAQQLQEEEDGLQEDQERRRSQEQR 869
EE E ++RQ +E + L+ ++E ++R E A +++ E + +E Q ++ E+
Sbjct: 1619 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1678
Query: 870 RDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQ 929
R Q EE +R R A E+ R+ Q L+ + + E + KR E+
Sbjct: 1679 R-----LQAEEAERRLRQ------AEVERARQVQVALETAQRSAEAELQSKRA-SFAEKT 1726
Query: 930 YREEEQLQQEEEQL--LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE 987
+ E LQ+E + LREE E+R +Q+ E + +++ ++ E L R R + E
Sbjct: 1727 AQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE 1786
Query: 988 KKYREEEELQQEEEQLLRE-EREKRRRQEWERQYRKKDELQQEE------------EQLL 1034
+ +++ Q E E+ E ERE RRR + E Q ++ EL ++E +Q L
Sbjct: 1787 EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRL 1846
Query: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERE--TRRRQELERQYRKEEELQQEEEQ 1092
E+E RL+ Q ++ +L +EE L E T++RQELE + K ++ E E
Sbjct: 1847 AAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK---VRAEMEV 1903
Query: 1093 LL----REEPEKRRRQERERQCREEE-----ELQQEEEQL--LREEREKRRR---QELER 1138
LL R E E R E+ +Q E E EL +E +L L EE +++R+ ++ R
Sbjct: 1904 LLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAAR 1963
Query: 1139 QYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE--QEKRRQERE 1196
Q E E V E+ + E R + E E +E+E + +L +E Q +R +E+
Sbjct: 1964 QRAEAERVLAEKLAAIGEAT--RLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQA 2021
Query: 1197 RQYREE-EELQRQKRK----QRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFR 1251
Q++ + EE Q RK + R + D Q +E + + K +
Sbjct: 2022 AQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAEL 2081
Query: 1252 QLEDSQLRDR-----QSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE 1306
+LE ++R +S++ + Q++ E+ERRR + +R ++ L EE E
Sbjct: 2082 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER---VQKSLAAEE--E 2136
Query: 1307 AKRRDRKSQEEKQLLREEREEKRR-RQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365
A R+ + + EE + L+ + EE RR R+ +++ + QL QE ++ L+ +E+ F +
Sbjct: 2137 AARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ 2196
Query: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425
+ + Q + L++EQ + Q R + E R E ++ R +R+ + +Q+
Sbjct: 2197 QKEQELQ--QTLQQEQSVLDQLRG----EAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2250
Query: 1426 QERDRKFREEEQQVR--------------RQERERKFLEEEQQLRQ--------ERHRKF 1463
ER ++ EE+ Q R QE R+ E+ LRQ E+H+KF
Sbjct: 2251 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2310
Query: 1464 REEEQLLQEREEQ-------QLHRQERDRKFLEEEQQLRRQE-----RDRKFREQELRSQ 1511
E+ + + EQ QL + + L+EE Q + E R R E+EL S
Sbjct: 2311 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2370
Query: 1512 EPERKFLEEEQQLHRQQRQRKFLQEEQQLRR--QERGQQRRQDRDRKFR------EEEQL 1563
+ + L + + + + L+++ +R QE ++ +Q + R E +L
Sbjct: 2371 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2430
Query: 1564 RQEREE---QQLSRQERDRKFR----------------LEEQKVRRQEQERKFMEDEQQL 1604
RQ EE QQ + E+ K + L++QK QEQ R+ ED++Q+
Sbjct: 2431 RQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQM 2490
Query: 1605 RRQEGQQQLRQERDRKFREDEQLLQEREEQQLH----RQERDRKFLEEEPQLRRQEREQ- 1659
+Q ++ +R + QL E ++L R + EE+ Q R++ E+
Sbjct: 2491 AQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2550
Query: 1660 -QLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQ---Q 1715
+ H + +E+ L+Q E ++RQ+ D + + ERE++ LQ+E Q
Sbjct: 2551 GEKLHRTELATQEKVTLVQTLE---IQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2607
Query: 1716 LRRQELERKFREEEQLRQET---------EQEQLRRQERYRKILEEEQLRPE---REEQQ 1763
L+ +E++ ++EQL QET E++ L ++ER+ +E+E+ + E ++E
Sbjct: 2608 LKSEEMQTV--QQEQLLQETQALQQSFLSEKDSLLQRERF---IEQEKAKLEQLFQDEVA 2662
Query: 1764 LRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE-EEQLRQEREE-QQLRPQQRDGKY 1821
+Q R+ + R+++Q+ QER+ +E+ R+ E EE +R+++EE QQL Q+R +
Sbjct: 2663 KAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEE 2722
Query: 1822 RWEEEQLQLEEQEQRL-RQERDRQYRAEEQFATQEKSRR-------------EEQELWQE 1867
EE +L EQ Q L Q R +EE A+Q + + E E
Sbjct: 2723 LLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHS 2782
Query: 1868 EEQKRRQERERKLREEHI---RRQQKEEQRHRQVGEIKSQEGKGH 1909
+ RR+ ++L+E I Q+ Q H V E+ +E H
Sbjct: 2783 FDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRH 2827
Score = 321 bits (822), Expect = 5e-87
Identities = 452/1778 (25%), Positives = 777/1778 (43%), Gaps = 303/1778 (17%)
Query: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ--LRREQQL-----------RR 421
Q LRR+ QL R L + L+ E+Q + L Q LR Q R
Sbjct: 1034 QSLRRDVQLIRSWSLATFRTLKPEEQRQALHSLELHYQAFLRDSQDAGGFGPEDRLMAER 1093
Query: 422 E------------QQLRREQEEERHEQKHEQERREQRLKREQEERRDW----LKREEETE 465
E Q L + +EE Q+ E ++ RL+ E E R L ++E
Sbjct: 1094 EYGSCSHHYQQLLQSLEQGAQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPA 1153
Query: 466 RHEQERRKQQLKRDQEEE-----------RRERWLKLEEEERREQQERREQQLRREQ-EE 513
R +R +Q K E E E+ L L E R E +L + E+
Sbjct: 1154 RECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQ 1213
Query: 514 RREQRLKRQEEEERLQQRLR----SEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
R E+ + + +R +E+ LR +E+ +E LE + + R
Sbjct: 1214 VRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLR 1273
Query: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER 629
Q E + + R + R +E ERL+QR +VE ER Q L ER
Sbjct: 1274 AQAEAQQPTF--DALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLL-------ER 1324
Query: 630 RQQLLKSEEQEERRQQQLRREQQERRE---------QRLKREEEE---------ERLEQR 671
Q +L + +R +QL R+ + RE Q +R +E+ + + ++
Sbjct: 1325 WQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQ 1384
Query: 672 LKREH---EEERREQELAEEEQEQARERIKS------RIPKWQWQLESEADARQSKVYSR 722
L++E EE R E EE Q A++ I + ++ ++ QLE A + +
Sbjct: 1385 LRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK-----K 1439
Query: 723 PRKQEGQRRRQEQEEKRRRRESEL----------------QWQEEERAHRQQQEEEQRRD 766
P+ Q G ++ R SEL + +EEER QQ+ EE+ R
Sbjct: 1440 PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER- 1498
Query: 767 FTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQR-EQRFLPEEEEKEQRRRQRR 825
+ E E+ RQ A + Q ER+ A+E QQR ++ + EE ++Q+R
Sbjct: 1499 ---LAEVEAALEKQRQLAEAHAQAKAQAERE--AKELQQRMQEEVVRREEAAVDAQQQKR 1553
Query: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR 885
++ELQ L + + + + +A+Q + E + R R +E+ R R QLE ++R
Sbjct: 1554 SIQEELQQLRQSSEAEIQAKARQAEAAE------RSRLRIEEEIRVV--RLQLEATERQR 1605
Query: 886 ---RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQER------------QY 930
L A A E+ +++ QEE E L+R+ +++ +R+ Q
Sbjct: 1606 GGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAA 1665
Query: 931 REEEQLQQ--EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK 988
RE+++ Q EE +L EE E+R RQ + R+ + + ++ E + +R EK
Sbjct: 1666 REKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEK 1725
Query: 989 KYREEEELQQEEEQL--LREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
+ E LQ+E + LREE E+R +Q+ E + R ++E ++E E+ + E RL+ +
Sbjct: 1726 TAQLERSLQEEHVAVAQLREEAERRAQQQAEAE-RAREEAERELERWQLKANEALRLRLQ 1784
Query: 1047 ERQYREEEELQQEEEQLLGEE--RETRRRQELERQYRKEEELQQEE----EQLLREEPEK 1100
+ +++ L Q E + EE RE RRR + E Q ++ EL ++E QL ++
Sbjct: 1785 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1844
Query: 1101 RRRQERER-QCREEEELQQEEEQLLREEREK---------RRRQELERQYREEEEVQQEE 1150
R E+E + R E E +++ QLL EE + ++RQELE E +V+ E
Sbjct: 1845 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA---ELAKVRAEM 1901
Query: 1151 EQLL----REEPEKRRRQELERQYREEE-----ELQQEEEQLLREEQEKRRQERERQYRE 1201
E LL R E E R E +Q E E EL +E +L +E +RQ RQ E
Sbjct: 1902 EVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ---RQLAE 1958
Query: 1202 EEELQRQKRKQRYRDEDQRS-DLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQL-- 1258
E+ +++ +R E + + + E E A+++ K ENE+ R+L + +
Sbjct: 1959 EDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKE-----KEAENERLRRLAEDEAFQ 2013
Query: 1259 RDRQSQQDLQH-------LLGEQQERDREQERRRWQQRD----RHFPEEEQLEREEQKEA 1307
R R +Q QH L ++ D E ER++ D R EEE L + E
Sbjct: 2014 RRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEK 2073
Query: 1308 KR-----------RDRKSQEEKQLLREEREEKRRRQ-----ETDRKFREEEQLLQEREEQ 1351
R R + E+ +E+ E + RQ E +R+ RE E ER ++
Sbjct: 2074 AAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE----ERVQK 2129
Query: 1352 PLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR-------------QERERKFLKEEQQ 1398
L +E + R+ L E+ + +EE +RLR QE +K L+ E++
Sbjct: 2130 SLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEK 2189
Query: 1399 LRC---QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ-ERE----RKFLE 1450
Q++EQ+L+Q ++ +Q E R+ EE ++ R Q ERE R+ +E
Sbjct: 2190 AHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2249
Query: 1451 EEQQLRQERHRKFREE-------EQLLQEREEQQLHRQERDRKFLEEEQQLRRQ-ERDRK 1502
E ++L+Q + + E+L +E E++ R + ++ L ++Q + E+ +K
Sbjct: 2250 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2309
Query: 1503 FREQELRSQ-EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561
F EQ LR + + E++ QL Q+ L EE Q + E + RQ R EEE
Sbjct: 2310 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQ---RSQVEEE 2366
Query: 1562 QLRQEREEQQLSRQERDRKFRLEEQK----VRRQEQERKFMEDEQQLRRQEGQQQLRQER 1617
+ ++LS+ K R+E + +R ++ ++F+++E + +Q ++ R
Sbjct: 2367 LFSVRVQMEELSKL----KARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV 2422
Query: 1618 DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQ 1677
+ E +L Q EE ++ K L+E+ Q ++ + + E +LLQ
Sbjct: 2423 AAQ--EAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT----------RLKAEAELLQ 2470
Query: 1678 EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ 1737
+ +E QE+ R+ +E+++Q+ +Q L EE Q ++ LE + + + ++ E E+
Sbjct: 2471 QQKELA---QEQARRLQEDKEQMAQQ------LAEETQGFQRTLEAERQRQLEMSAEAER 2521
Query: 1738 EQLRRQERYRKILEEEQLRPEREEQQLRRQERD--RKFREEEQLRQER----EEQQLRSQ 1791
+LR E R Q R E + Q+ R+Q + K E QE+ + +++ Q
Sbjct: 2522 LKLRVAEMSRA-----QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2576
Query: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYR----- 1846
+SD + E E ++ + QQ + + E++Q +QEQ L++ + Q
Sbjct: 2577 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2636
Query: 1847 ----AEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIK 1902
E+F QEK++ E+ L+Q+E K +Q RE + +RQQ++ ++ RQ
Sbjct: 2637 DSLLQRERFIEQEKAKLEQ--LFQDEVAKAQQLREEQ------QRQQQQMEQERQRLVAS 2688
Query: 1903 SQEGKGHGRLLEPGTHQFASVPVRSSPLYEYIQEQRSQ 1940
+E + E G + + L + Q++R Q
Sbjct: 2689 MEEARRRQHEAEEGVRR------KQEELQQLEQQRRQQ 2720
Score = 311 bits (798), Expect = 3e-84
Identities = 324/1270 (25%), Positives = 597/1270 (47%), Gaps = 197/1270 (15%)
Query: 98 EKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE- 156
+ +A+ + + LQ R QEE RR + ++ + +R Q+ +Q R+ +E E Q++
Sbjct: 1518 QAKAQAEREAKELQQRMQEEVVRR---EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKA 1574
Query: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERR-AEEEQLQSCKGHETEEFPDEEQLRRREL 215
+Q +R R R +EE+ R + + E +R E +LQ+ + EE +++ + E
Sbjct: 1575 RQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRA-RAEEAEAQKRQAQEEA 1633
Query: 216 LELRRKGREEKQQQRR---ERQDRVFQEEEEKEWRKRETVLRKE--------EEKLQEEE 264
LRR+ ++E Q++R+ E RV E E ++R +E E +L++ E
Sbjct: 1634 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1693
Query: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
+R R++Q E ++ EL+ +R ++ +L R Q + RE+ E R +Q
Sbjct: 1694 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1753
Query: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
Q E+ E E++L R Q + E R Q EE +Q+ + E E+++++ RE + R
Sbjct: 1754 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1813
Query: 385 ---REQQLRR----EQQLRREQQLRR---EQQLRREQQLRR----------EQQLRREQQ 424
EQ +R+ EQ+L +++QL +Q+L EQ+L R ++QL E+
Sbjct: 1814 GKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEEL 1873
Query: 425 LRREQEEERHEQKHEQ-ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD---- 479
R ++E QK ++ E +++ E E R EE R E+ KQ+L+ +
Sbjct: 1874 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1933
Query: 480 -------------QEEERRERWLKLEEEERREQQERR-----------------EQQLRR 509
EE +R+R L E+ R+ + R E ++
Sbjct: 1934 RELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL 1993
Query: 510 EQEERREQRLKRQEEEERLQQRLRSEQ--QLRREQEERREQLLKR-----EEEKRLEQER 562
+++E +RL+R E+E Q+R EQ Q + + EER QL K E +K L ++
Sbjct: 1994 KEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDT 2053
Query: 563 REQRLKREQE---------------------------ERRDQLLKREEER---------- 585
QR + E+E D L +E+
Sbjct: 2054 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 2113
Query: 586 -RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
++R +RE EER+++ L EE E Q + + ++R + + E ++L + EQE RQ
Sbjct: 2114 AEEERRRREAEERVQKSLAAEE-EAARQRKAALEEVERLKAKVEEARRLRERAEQESARQ 2172
Query: 645 QQLRREQQERREQRLKR------EEEEERLEQRLKREH---EEERREQELAE---EEQEQ 692
QL +E ++R Q ++ +++E+ L+Q L++E ++ R E E A EE E+
Sbjct: 2173 LQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2232
Query: 693 ARERIKSRIPKWQWQLESEADARQS---KVYSRPRKQ---EGQRRRQEQEEKRRRRESEL 746
AR + + + + Q+E +QS + +R + Q E R+ EQE RR + +
Sbjct: 2233 ARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQA 2292
Query: 747 QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA-----RPPLREQRERQLRAE 801
++++ A + ++ ++ + T + +A+ + E RL + L ++ ++L+AE
Sbjct: 2293 ALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2352
Query: 802 ERQQREQRFLPEEE--------EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
+ QR EEE E+ + + R E E L +++ QR LQEE
Sbjct: 2353 ATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR-----FLQEEA 2407
Query: 854 DGLQE--DQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEE 911
+ +++ ++ R S + + R EE+ ++R AL E++ KE+ +E
Sbjct: 2408 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQR-------ALAEKMLKEKMQAVQEAT 2460
Query: 912 ELQRE----EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967
L+ E +++K QEQ R+ +E++ +Q +QL E + +R E ERQ + + +
Sbjct: 2461 RLKAEAELLQQQKELAQEQARRLQEDK--EQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2518
Query: 968 QKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR----QEWERQYRKK 1023
+ +L E + + + E R ++ ++ E+L R E + + Q E Q ++
Sbjct: 2519 AERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2578
Query: 1024 D-ELQQEEEQLLREEREKRRLQERER--QYREEEELQQEEEQLLGEERETRRR--QELER 1078
D + ++ E + EREK +LQ+ + Q + EE ++EQLL E + ++ E +
Sbjct: 2579 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDS 2638
Query: 1079 QYRKEEELQQEE---EQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135
++E ++QE+ EQL ++E K +Q RE Q R++++++QE ++L+ E RR
Sbjct: 2639 LLQRERFIEQEKAKLEQLFQDEVAK-AQQLREEQQRQQQQMEQERQRLVASMEEARR--- 2694
Query: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
RQ+ EE V++++E+L Q+LE+Q R++EEL EE Q LRE+ + ++
Sbjct: 2695 --RQHEAEEGVRRKQEEL----------QQLEQQRRQQEELLAEENQRLREQLQLLEEQH 2742
Query: 1196 ERQYREEEEL 1205
EE+
Sbjct: 2743 RAALAHSEEV 2752
Score = 212 bits (539), Expect = 3e-54
Identities = 221/808 (27%), Positives = 387/808 (47%), Gaps = 87/808 (10%)
Query: 88 ALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRR--QKRQEQE 145
A+G+AT L E KE+ + R+ + F+ R+LEE+ Q + ++R Q
Sbjct: 1978 AIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQ--RRRLEEQAAQHKADIEERLAQL 2035
Query: 146 RELAEGEEQSEKQERLEQRDRQRR--DEELWRQRQEWQEREERRAE-EEQLQSCKGHETE 202
R+ ++ E + +K +E RQRR +EE+ + +++ +AE E +L + +
Sbjct: 2036 RKASDSELERQK-GLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA-- 2092
Query: 203 EFPDEEQLRRRELLEL----RRKGREEKQQQRRERQDRVFQE--EEEKEWRKRETVLRKE 256
E+ LR +E EL +R+ E++++RRE ++RV + EE+ R+R+ L +
Sbjct: 2093 ----EDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2148
Query: 257 EE-KLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL---RREQQLRRKQEE 312
E K + EE +R RE E+E + QE ++R + E++ ++EQ+L++ ++
Sbjct: 2149 ERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQ 2208
Query: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER 372
E+ + R E + R EE E R Q ER Q RR+ EE R +Q EQ + R
Sbjct: 2209 EQSVLDQLRGEAEAARRAAEEAEE---ARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2265
Query: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLR----------REQQLRREQQLRRE 422
+ Q E +LR+E + ++ + EQ R++Q EQ LR++ Q+ +E
Sbjct: 2266 AQAQAAAE-KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQE 2324
Query: 423 QQLRREQEEERHEQKHEQERREQRLKREQEE---RRDWLKREEETERHEQERRKQQLKRD 479
R Q EE QK+ + QRLK E E +R ++ E + R + E + R
Sbjct: 2325 LTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2384
Query: 480 QEEER------RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
+ E R ++ + +EE + ++ E+ R + RL++ EE+ QQR
Sbjct: 2385 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2444
Query: 534 SEQQLRREQEERRE--------QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585
+E+ L+ + + +E +LL++++E EQ RR Q E +E+ Q L E +
Sbjct: 2445 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ----EDKEQMAQQLAEETQG 2500
Query: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ 645
Q+ L+ E++ +LE + E ++ E R Q E+ + R+Q E E+ +
Sbjct: 2501 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ---AEEIGEKLHRT 2557
Query: 646 QLRREQQERREQRLK-REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKW 704
+L +++ Q L+ + ++ + +RL+ E RE+E ++E + + + +
Sbjct: 2558 ELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQ 2617
Query: 705 QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR 764
Q QL E A Q S + R EQE+ + Q ++E A QQ EEQ+
Sbjct: 2618 QEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE-----QLFQDEVAKAQQLREEQQ 2672
Query: 765 RDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQR 824
R +++ E+ RQRL A + E R RQ AEE +R+Q EE +Q +QR
Sbjct: 2673 RQ-------QQQMEQERQRLVA--SMEEARRRQHEAEEGVRRKQ------EELQQLEQQR 2717
Query: 825 REREKELQFLEEEEQLQRRERAQQLQEE 852
R++E+ L EE + RE+ Q L+E+
Sbjct: 2718 RQQEE----LLAEENQRLREQLQLLEEQ 2741
Score = 151 bits (382), Expect = 5e-36
Identities = 162/632 (25%), Positives = 294/632 (46%), Gaps = 80/632 (12%)
Query: 99 KRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQ-----------ERE 147
+RA + +E+ +Q R+ RR Q+EE +R +Q +EQ E+
Sbjct: 2224 RRAAEEAEEARVQAEREAAQSRR------QVEE--AERLKQSAEEQAQARAQAQAAAEKL 2275
Query: 148 LAEGEEQSEKQERLEQ---RDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
E E+++ ++ + EQ R +Q D E+ + ++ ++ ++A+ EQ + + EE
Sbjct: 2276 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2335
Query: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQD----RVFQEEEEK-----EWRKRETVLRK 255
++ L EL L+ + E +Q+ + ++ RV EE K E R +LR
Sbjct: 2336 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD 2395
Query: 256 EE--EKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ--EEEQQQQRLRREQQLRRK-- 309
++ ++ +EE ++ +++ EE +L + QE R RQ EE+ QQR E+ L+ K
Sbjct: 2396 KDNTQRFLQEEAEKMKQVAEEAARL-SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQ 2454
Query: 310 --QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE------EERRE 361
QE R + + E +QQ+ Q++ RR Q E +E+ QQL E + E R+
Sbjct: 2455 AVQEATRLKAEAELLQQQKELAQEQARRLQ----EDKEQMAQQLAEETQGFQRTLEAERQ 2510
Query: 362 QQLRREQEEER---REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
+QL E ER R ++ R Q E R +Q + +L ++++ Q
Sbjct: 2511 RQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT 2570
Query: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR 478
L ++Q E E E ER +++L Q+E + + EE + +QE+ Q+ +
Sbjct: 2571 LEIQRQQSDHDAERLREAIAELEREKEKL---QQEAKLLQLKSEEMQTVQQEQLLQETQA 2627
Query: 479 DQEEERRERWLKLEEEERREQQERREQQL-----RREQEERREQRLKRQEEEERLQQRLR 533
Q+ E+ L+ E EQ++ + +QL + Q+ R EQ+ ++Q+ E+ Q+ +
Sbjct: 2628 LQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVA 2687
Query: 534 SEQQLRREQEERREQLLKREEE-KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592
S ++ RR Q E E + +++EE ++LEQ+RR+Q ++LL E +R +++L+
Sbjct: 2688 SMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ----------EELLAEENQRLREQLQL 2737
Query: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRRE-- 650
+E+ EEV + + R+ + +E + E LRR+
Sbjct: 2738 LEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGP------AAEAEPEHSFDGLRRKVS 2791
Query: 651 QQERREQRLKREEEEERLEQRLKREHEEERRE 682
Q +E + EE +RL Q E RRE
Sbjct: 2792 AQRLQEAGILSAEELQRLAQGHTTVDELARRE 2823
Score = 96.3 bits (238), Expect = 3e-19
Identities = 86/335 (25%), Positives = 166/335 (49%), Gaps = 42/335 (12%)
Query: 80 KVAQACYYALGQATGLDEEKRARCDGKESLLQDRR------QEEDQRRFEPRDRQLEEEP 133
K+ Q A + E R R +E L Q R +E+ Q E + E E
Sbjct: 2409 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAEL 2468
Query: 134 GQRRRQKRQEQERELAEGEEQSEKQ--------ERLEQRDRQRRDE-----ELWRQRQEW 180
Q++++ QEQ R L E +EQ +Q +R + +RQR+ E E + R
Sbjct: 2469 LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAE 2528
Query: 181 QEREERRAEEEQLQSCKGHET-------EEFPDEEQLRRRELLELRRKGREEKQQQRRE- 232
R + RAEE+ + K E E +E++ + LE++R+ + ++ RE
Sbjct: 2529 MSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREA 2588
Query: 233 ------RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRK---LER 283
++++ QE + + + E ++E+ LQE + +Q L E++ L++ +E+
Sbjct: 2589 IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQ 2648
Query: 284 QELRRER--QEEEQQQQRLRREQQLRRKQEEERREQ----QEERREQQERREQQEERREQ 337
++ + E+ Q+E + Q+LR EQQ +++Q E+ R++ EE R +Q E+ R+++
Sbjct: 2649 EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQE 2708
Query: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEER 372
+L++ +++RR+Q+ +E +R +QL+ +E+ R
Sbjct: 2709 ELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHR 2743
Score = 37.4 bits (85), Expect = 0.14
Identities = 73/313 (23%), Positives = 122/313 (38%), Gaps = 57/313 (18%)
Query: 933 EEQLQQEEEQLLREEREKRRRQER----ERQYRKDKKLQQKEEQLL--GEEPEKRRRQER 986
E+QL+ E E+L +R + Q E Q + L Q + +LL G+ P++ ER
Sbjct: 518 EKQLRSEFERLECLQRIVTKLQMEAGLCEEQLNQADALLQSDVRLLAAGKVPQRAGEVER 577
Query: 987 E-KKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ-EEEQLLR--------- 1035
+ K L + Q L++ R + Q + R YR + L E LR
Sbjct: 578 DLDKADSMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPA 637
Query: 1036 EEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE----------LERQYRKEEE 1085
+ + LQ +R+ E+ + + LL E + R + +E Q
Sbjct: 638 TQVAQVTLQSVQRRPELEDSTLRYLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRG 697
Query: 1086 LQQEEEQLLREEPEKRRRQERE---------RQCREEEELQQEEEQLLREEREKRRRQEL 1136
L Q E+ R + E+ R E + R C +LQ + LL + + R E
Sbjct: 698 LHQSIEEF-RAKIERARSDEGQLSPATRGAYRDCLGRLDLQYAK--LLNSSKARLRSLES 754
Query: 1137 ERQY-------------REEEEV-----QQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178
+ +EEEEV + ++E +ELE + ++ +ELQ
Sbjct: 755 LHSFVAAATKELMWLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQN 814
Query: 1179 EEEQLLREEQEKR 1191
++LLRE+ R
Sbjct: 815 AGDRLLREDHPAR 827
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 342 bits (876), Expect = 3e-93
Identities = 446/1785 (24%), Positives = 774/1785 (43%), Gaps = 216/1785 (12%)
Query: 114 RQEEDQRRFEPRDRQL-EEEPG----------QRRRQKRQEQER------ELAEGEEQSE 156
R +D F P DR + E E G Q Q QE+ R EL + Q E
Sbjct: 916 RDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGAQEESRCQRCISELKDIRLQLE 975
Query: 157 KQE-RLEQRDRQRRDEELWRQ-RQEWQEREERRAEEEQL------QSCKGHETEEFPDEE 208
E R R R D+E R+ Q E+++ +AE E L S + + P+
Sbjct: 976 ACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPS 1035
Query: 209 QL--RRRELLELRRKGREEKQQQRRERQDRVFQEEEE------KEWRKRETVLRKEEEKL 260
R LEL E+ + ++ E+ + + + E VLR EE+L
Sbjct: 1036 PAAPTLRSELELTLGKLEQVRS-----LSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQL 1090
Query: 261 QEEE--PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318
+E + P EL+ + L+KL R + ++ + + LR Q++ + ++ E+
Sbjct: 1091 KEAQAVPATLPELEATKASLKKL-RAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERD 1149
Query: 319 EERREQQERREQQEERREQQLRREQEERRE-QQLRREQEEERRE-QQLRREQEEERREQQ 376
E +ER Q ER + L + +RE +QL R+ R L ++ RR Q+
Sbjct: 1150 VEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQE 1209
Query: 377 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE---- 432
+ L Q +R +QLR+EQ L E + R + E Q +Q + ++ E
Sbjct: 1210 QIQAMPLADSQAVR--EQLRQEQALLEE--IERHGEKVEECQRFAKQYINAIKDYELQLV 1265
Query: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR----------KQQLKRDQEE 482
++ + E + + Q ++ + H E + L+R +EE
Sbjct: 1266 TYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEE 1325
Query: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
ER + EE ER + E ++ R+ E + + + + E + LQQR++ E+ +RRE+
Sbjct: 1326 ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ-EEVVRREE 1384
Query: 543 EERREQLLKREEEKRLEQERRE-----QRLKREQEERRDQLLKREEERRQQRLKREQEER 597
Q KR ++ L+Q R+ Q R+ E L+ EEE R RL+ E ER
Sbjct: 1385 AAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATER 1444
Query: 598 -----------LEQRLKREEVERLEQEERREQRLKREEPEEERRQQ----LLKSEEQEER 642
L R + E ++ + +E E+ ++ + E +R++Q L + E
Sbjct: 1445 QRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAE 1504
Query: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIP 702
++ +R Q E RL+ EE E RL Q E E R+ Q E Q A ++S+
Sbjct: 1505 AAREKQRALQALEELRLQAEEAERRLRQ---AEVERARQVQVALETAQRSAEAELQSKRA 1561
Query: 703 KW-QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES---ELQ-WQ---EEERA 754
+ + + E ++ V ++E +RR Q+Q E R RE EL+ WQ E
Sbjct: 1562 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1621
Query: 755 HRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE- 813
R Q EE ++ Q +AE++ E + R EQ RQ E++ +QR L E
Sbjct: 1622 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEG 1681
Query: 814 --------EEEKEQRRRQRREREKELQFLEEE-EQLQRR-----ERAQQLQEEEDGLQED 859
E+E + R + + E++ Q LEEE +LQR ++ Q+L+ E ++ +
Sbjct: 1682 TAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAE 1741
Query: 860 QE-----RRRSQEQRR--DQKWRWQLEEERKRRRHTLYAKP---ALQEQLRKEQQLLQEE 909
E + R++E+ R +K + +LE E R R AL E+ ++++Q L EE
Sbjct: 1742 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQ-LAEE 1800
Query: 910 EEELQREEREK-------------RRRQEQERQYREEEQLQQEEEQLLREEREKRRR--- 953
+ QR E E+ R + E E +E+E + +L +E +RRR
Sbjct: 1801 DAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEE 1860
Query: 954 ---------QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
+ER Q RK + + ++ L E+ ++RRQ E+ + ++
Sbjct: 1861 QAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKA 1920
Query: 1005 REEREKRR-RQEWERQYRKKD--ELQQEEEQLLREEREKRRLQERERQYR----EEEELQ 1057
E E R R E R K+ EL+ ++ L E E+RR + ER + EEE +
Sbjct: 1921 ELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR 1980
Query: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117
Q + L ER + +E R + E+ + QL +E +KR + E + ++ +
Sbjct: 1981 QRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 2040
Query: 1118 QEEEQLLREERE--KRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175
QE +Q L++E+ + R E E R EE ++ Q RE + R RQ E E
Sbjct: 2041 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR------RQVEEAER 2094
Query: 1176 LQQE-EEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234
L+Q EEQ Q + E+ R+ E+E +R + +Q + Q +D E EK
Sbjct: 2095 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADA----EMEKHKK 2150
Query: 1235 VRDNKVYCKGRENEQFR----QLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRD 1290
+ + K + ++ QLE++ + ++LQ L E E R++ + +
Sbjct: 2151 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2210
Query: 1291 RHFPEEEQLEREEQKEAKRRD---RKSQEEKQLLREEREEKRRRQETDRKF----REEEQ 1343
EE + + + EA+ R R ++ L+EE E+ ++ E + +E +
Sbjct: 2211 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2270
Query: 1344 LLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQE 1403
L Q EE +++ K +E+++ ++ + E + L++Q K L +EQ R QE
Sbjct: 2271 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQ----KELAQEQARRLQE 2326
Query: 1404 REQQLRQDRDRKF----------REEEQQLSRQERDRKFREEEQ---QVRRQERERKFLE 1450
++Q+ Q + R+ + ++S + K R E Q R +E ++F +
Sbjct: 2327 DKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRK 2386
Query: 1451 EEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE--- 1507
+ +++ ++ HR ++ + + ++ RQ+ D + + ER+++ +QE
Sbjct: 2387 QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKL 2446
Query: 1508 LRSQEPERKFLEEEQQLHRQQR-QRKFLQEEQQLRRQERG-QQRRQDRDRKFREE----E 1561
L+ + E + +++EQ L Q Q+ FL E+ L ++ER +Q + ++ F++E +
Sbjct: 2447 LQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQ 2506
Query: 1562 QLRQERE-EQQLSRQERDRKFRLEEQKVRRQ----EQERKFMEDEQQLRRQEGQQ-QLRQ 1615
QLR+E++ +QQ QER R E+ RRQ E R+ E+ QQL +Q QQ +L
Sbjct: 2507 QLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLA 2566
Query: 1616 ERDRKFREDEQLLQEREEQQLHRQER--------DRKFLEEEPQLRRQEREQQLRHDRDR 1667
E +++ RE QLL+E+ L E + L E + H D
Sbjct: 2567 EENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDG 2626
Query: 1668 KFRE-EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ 1711
R+ Q LQE +R + +L R+E R +LQ
Sbjct: 2627 LRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQ 2671
Score = 326 bits (836), Expect = 1e-88
Identities = 360/1355 (26%), Positives = 617/1355 (45%), Gaps = 193/1355 (14%)
Query: 113 RRQEEDQR-----RFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQ 167
RR EE++R R E R+R E E E++R+LAE Q++ Q E ++ Q
Sbjct: 1320 RRMEEEERLAEQQRAEERERLAEVEAA-------LEKQRQLAEAHAQAKAQAEREAKELQ 1372
Query: 168 RR--DEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE- 224
+R +E + R+ ++++R+ +E+LQ QLR+ E++ K R+
Sbjct: 1373 QRMQEEVVRREEAAVDAQQQKRSIQEELQ--------------QLRQSSEAEIQAKARQA 1418
Query: 225 ---EKQQQRRERQDRVFQEEEEKEWRKR---ETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
E+ + R E + RV + + E R+R E L+ + +E E Q+ R+ QEE E+L
Sbjct: 1419 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK-RQAQEEAERL 1477
Query: 279 RKLERQELRRERQEEEQQQQRLRREQQLRRKQE------EERREQQEERREQQERREQQE 332
R+ + E +R+RQ E + R++ E + R+++ EE R Q EE E++ R+ + E
Sbjct: 1478 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE-AERRLRQAEVE 1536
Query: 333 ERREQQLRREQEER---REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
R+ Q+ E +R E Q +R E+ Q R QEE QLR E + R +QQ
Sbjct: 1537 RARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQA 1596
Query: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
E+ ++ QL+ + LR Q Q + + E +QK E ER +R +
Sbjct: 1597 EAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGK 1656
Query: 450 EQEE---RRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506
+E+ +R+ ++E E +R E QQ ++E R L+ E E+ +Q++ E++
Sbjct: 1657 AEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR---LRAETEQGEQQRQLLEEE 1713
Query: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566
L R Q E KRQE E L ++R E E + EEE R E+ +QR
Sbjct: 1714 LARLQREAAAATQKRQELEAEL-------AKVRAEMEVLLASKARAEEESRSTSEKSKQR 1766
Query: 567 LKRE------------------QEERRDQLLKREEERRQQ------------------RL 590
L+ E +E +R + L E+ RQ+ RL
Sbjct: 1767 LEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRL 1826
Query: 591 KREQEERL-EQRLKREEVERLEQEERREQRLKREEPE------EERRQQLLKSEEQEERR 643
K E E L E+ + E + RL ++E ++R E+ EER QL K+ + E R
Sbjct: 1827 KTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELER 1886
Query: 644 QQQL------RREQQERREQRLK--------------------REEEEERLEQRLKREHE 677
Q+ L +R Q E LK R E+ L + + E E
Sbjct: 1887 QKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELE 1946
Query: 678 EERREQELAEEE--QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQ 735
R+ Q AEEE + +A ER++ + + + + A +V K E RR +E+
Sbjct: 1947 AARQRQLAAEEERRRREAEERVQKSLAA-EEEAARQRKAALEEVERLKAKVEEARRLRER 2005
Query: 736 EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRE 795
E+ R+ +L +E A ++ Q EE+ F Q + +E + +Q S LR + E
Sbjct: 2006 AEQESARQLQL---AQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2062
Query: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDG 855
RA E + E+ + E E Q RRQ E E+ Q EEQ Q R +AQ E+
Sbjct: 2063 AARRAAE--EAEEARVQAEREAAQSRRQVEEAERLKQ--SAEEQAQARAQAQAAAEKLRK 2118
Query: 856 LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL----LQEEEE 911
E + RR+Q ++ + + + E + +H +A+ L+++ + EQ+L LQ EE
Sbjct: 2119 EAEQEAARRAQAEQAALRQKQAADAEME--KHKKFAEQTLRQKAQVEQELTTLRLQLEET 2176
Query: 912 ELQR---EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
+ Q+ +E +R + E R+ Q+++E + + E + + R + L+
Sbjct: 2177 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD 2236
Query: 969 KE--EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
K+ ++ L EE EK ++ E + + L EE ++R E+ ++K +
Sbjct: 2237 KDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQA 2296
Query: 1027 QQEEEQLLRE----EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK 1082
QE +L E +++K QE+ R+ +E++E Q +QL E + +R E ERQ +
Sbjct: 2297 VQEATRLKAEAELLQQQKELAQEQARRLQEDKE--QMAQQLAEETQGFQRTLEAERQ--R 2352
Query: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYRE 1142
+ E+ E E+L E R Q R EE+ Q+ +Q E EK R EL Q +
Sbjct: 2353 QLEMSAEAERLKLRVAEMSR-----AQARAEEDAQRFRKQ-AEEIGEKLHRTELATQEKV 2406
Query: 1143 EEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREE 1202
E ++ + +R R+ + RE+E+LQQE + L + +E + ++E+ +E
Sbjct: 2407 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQET 2466
Query: 1203 EELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQ 1262
+ LQ Q + E + S L+ + E+E A + + + +Q R E+ Q + +Q
Sbjct: 2467 QALQ-----QSFLSE-KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR--EEQQRQQQQ 2518
Query: 1263 SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR 1322
+Q+ Q L+ +E R Q E E+ R +Q+E ++ +++ +++++LL
Sbjct: 2519 MEQERQRLVASMEEARRRQH------------EAEEGVRRKQEELQQLEQQRRQQEELLA 2566
Query: 1323 EEREEKRRRQETDRKFREEEQLLQEREEQPLRRQE 1357
EE +++ RE+ QLL+E+ L E
Sbjct: 2567 EE----------NQRLREQLQLLEEQHRAALAHSE 2591
Score = 324 bits (830), Expect = 6e-88
Identities = 461/1845 (24%), Positives = 811/1845 (43%), Gaps = 259/1845 (14%)
Query: 253 LRKEEEK--LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQ 310
L+ EE++ L E Q L++ ++ L ER+ + Q L +
Sbjct: 895 LKPEEQRQALHSLELHYQAFLRDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGA 954
Query: 311 EEERREQQ--EERREQQERREQQEERREQQLR--------REQEERREQQLRREQEEERR 360
+EE R Q+ E ++ + + E E R +LR RE +R +Q + + E E
Sbjct: 955 QEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGL 1014
Query: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
+ + R E E+ L + LR E +L L + +Q+R + E+
Sbjct: 1015 GKGVARLSAEA--EKVLALPEPSPAAPTLRSELELT----LGKLEQVRSLSAIYLEKLKT 1068
Query: 421 REQQLRREQEEERHEQKHEQERREQRLKR----EQEERRDWLKR---EEETERHEQERRK 473
+R Q E + HE++ +E + E E + LK+ + E ++ + +
Sbjct: 1069 ISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALR 1128
Query: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
+L+ QE R + E + E+ R QL + Q RQ E E+L ++LR
Sbjct: 1129 DELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLR 1188
Query: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE 593
+ E + L ++ R QE+ + + + R+QL R+E+ + ++R
Sbjct: 1189 YYR-------ESADPLGAWLQDARRRQEQIQAMPLADSQAVREQL--RQEQALLEEIERH 1239
Query: 594 QEERLE-QRLKREEVERLEQEERREQRLKRE-EP--EEERRQQLLKSEEQEERRQQQLRR 649
E+ E QR ++ + ++ E + K + EP ++ ++ E + LR
Sbjct: 1240 GEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRT 1299
Query: 650 EQQERR----------EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
E + L+R EEEERL ++ + E E E E A E+Q Q
Sbjct: 1300 HYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQL------ 1353
Query: 700 RIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQ- 758
+EA A+ R K+ QR QEE RR E+ + Q+++R+ +++
Sbjct: 1354 ----------AEAHAQAKAQAEREAKELQQRM---QEEVVRREEAAVDAQQQKRSIQEEL 1400
Query: 759 QEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQ-----REQRFLPE 813
Q+ Q + Q +A + R RL +R R QL A ERQ+ Q
Sbjct: 1401 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVR-LQLEATERQRGGAEGELQALRAR 1459
Query: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRR----ERAQQLQEEEDGLQEDQERRRSQEQR 869
EE E ++RQ +E + L+ ++E ++R E A +++ E + +E Q ++ E+
Sbjct: 1460 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1519
Query: 870 RDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQ 929
R Q EE +R R A E+ R+ Q L+ + + E + KR E+
Sbjct: 1520 R-----LQAEEAERRLRQ------AEVERARQVQVALETAQRSAEAELQSKRA-SFAEKT 1567
Query: 930 YREEEQLQQEEEQL--LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE 987
+ E LQ+E + LREE E+R +Q+ E + +++ ++ E L R R + E
Sbjct: 1568 AQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE 1627
Query: 988 KKYREEEELQQEEEQLLRE-EREKRRRQEWERQYRKKDELQQEE------------EQLL 1034
+ +++ Q E E+ E ERE RRR + E Q ++ EL ++E +Q L
Sbjct: 1628 EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRL 1687
Query: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERE--TRRRQELERQYRKEEELQQEEEQ 1092
E+E RL+ Q ++ +L +EE L E T++RQELE + K ++ E E
Sbjct: 1688 AAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK---VRAEMEV 1744
Query: 1093 LL----REEPEKRRRQERERQCREEE-----ELQQEEEQL--LREEREKRRR---QELER 1138
LL R E E R E+ +Q E E EL +E +L L EE +++R+ ++ R
Sbjct: 1745 LLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAAR 1804
Query: 1139 QYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE--QEKRRQERE 1196
Q E E V E+ + E R + E E +E+E + +L +E Q +R +E+
Sbjct: 1805 QRAEAERVLAEKLAAIGEAT--RLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQA 1862
Query: 1197 RQYREE-EELQRQKRK----QRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFR 1251
Q++ + EE Q RK + R + D Q +E + + K +
Sbjct: 1863 AQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAEL 1922
Query: 1252 QLEDSQLRDR-----QSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE 1306
+LE ++R +S++ + Q++ E+ERRR + +R ++ L EE E
Sbjct: 1923 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER---VQKSLAAEE--E 1977
Query: 1307 AKRRDRKSQEEKQLLREEREEKRR-RQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365
A R+ + + EE + L+ + EE RR R+ +++ + QL QE ++ L+ +E+ F +
Sbjct: 1978 AARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ 2037
Query: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425
+ + Q + L++EQ + Q R + E R E ++ R +R+ + +Q+
Sbjct: 2038 QKEQELQ--QTLQQEQSVLDQLRG----EAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2091
Query: 1426 QERDRKFREEEQQVR--------------RQERERKFLEEEQQLRQ--------ERHRKF 1463
ER ++ EE+ Q R QE R+ E+ LRQ E+H+KF
Sbjct: 2092 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2151
Query: 1464 REEEQLLQEREEQ-------QLHRQERDRKFLEEEQQLRRQE-----RDRKFREQELRSQ 1511
E+ + + EQ QL + + L+EE Q + E R R E+EL S
Sbjct: 2152 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2211
Query: 1512 EPERKFLEEEQQLHRQQRQRKFLQEEQQLRR--QERGQQRRQDRDRKFR------EEEQL 1563
+ + L + + + + L+++ +R QE ++ +Q + R E +L
Sbjct: 2212 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2271
Query: 1564 RQEREE---QQLSRQERDRKFR----------------LEEQKVRRQEQERKFMEDEQQL 1604
RQ EE QQ + E+ K + L++QK QEQ R+ ED++Q+
Sbjct: 2272 RQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQM 2331
Query: 1605 RRQEGQQQLRQERDRKFREDEQLLQEREEQQLH----RQERDRKFLEEEPQLRRQEREQ- 1659
+Q ++ +R + QL E ++L R + EE+ Q R++ E+
Sbjct: 2332 AQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2391
Query: 1660 -QLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQ---Q 1715
+ H + +E+ L+Q E ++RQ+ D + + ERE++ LQ+E Q
Sbjct: 2392 GEKLHRTELATQEKVTLVQTLE---IQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2448
Query: 1716 LRRQELERKFREEEQLRQET---------EQEQLRRQERYRKILEEEQLRPE---REEQQ 1763
L+ +E++ ++EQL QET E++ L ++ER+ +E+E+ + E ++E
Sbjct: 2449 LKSEEMQTV--QQEQLLQETQALQQSFLSEKDSLLQRERF---IEQEKAKLEQLFQDEVA 2503
Query: 1764 LRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE-EEQLRQEREE-QQLRPQQRDGKY 1821
+Q R+ + R+++Q+ QER+ +E+ R+ E EE +R+++EE QQL Q+R +
Sbjct: 2504 KAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEE 2563
Query: 1822 RWEEEQLQLEEQEQRL-RQERDRQYRAEEQFATQEKSRR-------------EEQELWQE 1867
EE +L EQ Q L Q R +EE A+Q + + E E
Sbjct: 2564 LLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHS 2623
Query: 1868 EEQKRRQERERKLREEHI---RRQQKEEQRHRQVGEIKSQEGKGH 1909
+ RR+ ++L+E I Q+ Q H V E+ +E H
Sbjct: 2624 FDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRH 2668
Score = 321 bits (822), Expect = 5e-87
Identities = 452/1778 (25%), Positives = 777/1778 (43%), Gaps = 303/1778 (17%)
Query: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ--LRREQQL-----------RR 421
Q LRR+ QL R L + L+ E+Q + L Q LR Q R
Sbjct: 875 QSLRRDVQLIRSWSLATFRTLKPEEQRQALHSLELHYQAFLRDSQDAGGFGPEDRLMAER 934
Query: 422 E------------QQLRREQEEERHEQKHEQERREQRLKREQEERRDW----LKREEETE 465
E Q L + +EE Q+ E ++ RL+ E E R L ++E
Sbjct: 935 EYGSCSHHYQQLLQSLEQGAQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPA 994
Query: 466 RHEQERRKQQLKRDQEEE-----------RRERWLKLEEEERREQQERREQQLRREQ-EE 513
R +R +Q K E E E+ L L E R E +L + E+
Sbjct: 995 RECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQ 1054
Query: 514 RREQRLKRQEEEERLQQRLR----SEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
R E+ + + +R +E+ LR +E+ +E LE + + R
Sbjct: 1055 VRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLR 1114
Query: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER 629
Q E + + R + R +E ERL+QR +VE ER Q L ER
Sbjct: 1115 AQAEAQQPTF--DALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLL-------ER 1165
Query: 630 RQQLLKSEEQEERRQQQLRREQQERRE---------QRLKREEEE---------ERLEQR 671
Q +L + +R +QL R+ + RE Q +R +E+ + + ++
Sbjct: 1166 WQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQ 1225
Query: 672 LKREH---EEERREQELAEEEQEQARERIKS------RIPKWQWQLESEADARQSKVYSR 722
L++E EE R E EE Q A++ I + ++ ++ QLE A + +
Sbjct: 1226 LRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK-----K 1280
Query: 723 PRKQEGQRRRQEQEEKRRRRESEL----------------QWQEEERAHRQQQEEEQRRD 766
P+ Q G ++ R SEL + +EEER QQ+ EE+ R
Sbjct: 1281 PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER- 1339
Query: 767 FTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQR-EQRFLPEEEEKEQRRRQRR 825
+ E E+ RQ A + Q ER+ A+E QQR ++ + EE ++Q+R
Sbjct: 1340 ---LAEVEAALEKQRQLAEAHAQAKAQAERE--AKELQQRMQEEVVRREEAAVDAQQQKR 1394
Query: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR 885
++ELQ L + + + + +A+Q + E + R R +E+ R R QLE ++R
Sbjct: 1395 SIQEELQQLRQSSEAEIQAKARQAEAAE------RSRLRIEEEIRVV--RLQLEATERQR 1446
Query: 886 ---RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQER------------QY 930
L A A E+ +++ QEE E L+R+ +++ +R+ Q
Sbjct: 1447 GGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAA 1506
Query: 931 REEEQLQQ--EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK 988
RE+++ Q EE +L EE E+R RQ + R+ + + ++ E + +R EK
Sbjct: 1507 REKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEK 1566
Query: 989 KYREEEELQQEEEQL--LREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
+ E LQ+E + LREE E+R +Q+ E + R ++E ++E E+ + E RL+ +
Sbjct: 1567 TAQLERSLQEEHVAVAQLREEAERRAQQQAEAE-RAREEAERELERWQLKANEALRLRLQ 1625
Query: 1047 ERQYREEEELQQEEEQLLGEE--RETRRRQELERQYRKEEELQQEE----EQLLREEPEK 1100
+ +++ L Q E + EE RE RRR + E Q ++ EL ++E QL ++
Sbjct: 1626 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1685
Query: 1101 RRRQERER-QCREEEELQQEEEQLLREEREK---------RRRQELERQYREEEEVQQEE 1150
R E+E + R E E +++ QLL EE + ++RQELE E +V+ E
Sbjct: 1686 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA---ELAKVRAEM 1742
Query: 1151 EQLL----REEPEKRRRQELERQYREEE-----ELQQEEEQLLREEQEKRRQERERQYRE 1201
E LL R E E R E +Q E E EL +E +L +E +RQ RQ E
Sbjct: 1743 EVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ---RQLAE 1799
Query: 1202 EEELQRQKRKQRYRDEDQRS-DLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQL-- 1258
E+ +++ +R E + + + E E A+++ K ENE+ R+L + +
Sbjct: 1800 EDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKE-----KEAENERLRRLAEDEAFQ 1854
Query: 1259 RDRQSQQDLQH-------LLGEQQERDREQERRRWQQRD----RHFPEEEQLEREEQKEA 1307
R R +Q QH L ++ D E ER++ D R EEE L + E
Sbjct: 1855 RRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEK 1914
Query: 1308 KR-----------RDRKSQEEKQLLREEREEKRRRQ-----ETDRKFREEEQLLQEREEQ 1351
R R + E+ +E+ E + RQ E +R+ RE E ER ++
Sbjct: 1915 AAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE----ERVQK 1970
Query: 1352 PLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR-------------QERERKFLKEEQQ 1398
L +E + R+ L E+ + +EE +RLR QE +K L+ E++
Sbjct: 1971 SLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEK 2030
Query: 1399 LRC---QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ-ERE----RKFLE 1450
Q++EQ+L+Q ++ +Q E R+ EE ++ R Q ERE R+ +E
Sbjct: 2031 AHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2090
Query: 1451 EEQQLRQERHRKFREE-------EQLLQEREEQQLHRQERDRKFLEEEQQLRRQ-ERDRK 1502
E ++L+Q + + E+L +E E++ R + ++ L ++Q + E+ +K
Sbjct: 2091 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2150
Query: 1503 FREQELRSQ-EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561
F EQ LR + + E++ QL Q+ L EE Q + E + RQ R EEE
Sbjct: 2151 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQ---RSQVEEE 2207
Query: 1562 QLRQEREEQQLSRQERDRKFRLEEQK----VRRQEQERKFMEDEQQLRRQEGQQQLRQER 1617
+ ++LS+ K R+E + +R ++ ++F+++E + +Q ++ R
Sbjct: 2208 LFSVRVQMEELSKL----KARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV 2263
Query: 1618 DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQ 1677
+ E +L Q EE ++ K L+E+ Q ++ + + E +LLQ
Sbjct: 2264 AAQ--EAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT----------RLKAEAELLQ 2311
Query: 1678 EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ 1737
+ +E QE+ R+ +E+++Q+ +Q L EE Q ++ LE + + + ++ E E+
Sbjct: 2312 QQKELA---QEQARRLQEDKEQMAQQ------LAEETQGFQRTLEAERQRQLEMSAEAER 2362
Query: 1738 EQLRRQERYRKILEEEQLRPEREEQQLRRQERD--RKFREEEQLRQER----EEQQLRSQ 1791
+LR E R Q R E + Q+ R+Q + K E QE+ + +++ Q
Sbjct: 2363 LKLRVAEMSRA-----QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2417
Query: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYR----- 1846
+SD + E E ++ + QQ + + E++Q +QEQ L++ + Q
Sbjct: 2418 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2477
Query: 1847 ----AEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIK 1902
E+F QEK++ E+ L+Q+E K +Q RE + +RQQ++ ++ RQ
Sbjct: 2478 DSLLQRERFIEQEKAKLEQ--LFQDEVAKAQQLREEQ------QRQQQQMEQERQRLVAS 2529
Query: 1903 SQEGKGHGRLLEPGTHQFASVPVRSSPLYEYIQEQRSQ 1940
+E + E G + + L + Q++R Q
Sbjct: 2530 MEEARRRQHEAEEGVRR------KQEELQQLEQQRRQQ 2561
Score = 311 bits (798), Expect = 3e-84
Identities = 324/1270 (25%), Positives = 597/1270 (47%), Gaps = 197/1270 (15%)
Query: 98 EKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE- 156
+ +A+ + + LQ R QEE RR + ++ + +R Q+ +Q R+ +E E Q++
Sbjct: 1359 QAKAQAEREAKELQQRMQEEVVRR---EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKA 1415
Query: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERR-AEEEQLQSCKGHETEEFPDEEQLRRREL 215
+Q +R R R +EE+ R + + E +R E +LQ+ + EE +++ + E
Sbjct: 1416 RQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRA-RAEEAEAQKRQAQEEA 1474
Query: 216 LELRRKGREEKQQQRR---ERQDRVFQEEEEKEWRKRETVLRKE--------EEKLQEEE 264
LRR+ ++E Q++R+ E RV E E ++R +E E +L++ E
Sbjct: 1475 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1534
Query: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
+R R++Q E ++ EL+ +R ++ +L R Q + RE+ E R +Q
Sbjct: 1535 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1594
Query: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
Q E+ E E++L R Q + E R Q EE +Q+ + E E+++++ RE + R
Sbjct: 1595 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1654
Query: 385 ---REQQLRR----EQQLRREQQLRR---EQQLRREQQLRR----------EQQLRREQQ 424
EQ +R+ EQ+L +++QL +Q+L EQ+L R ++QL E+
Sbjct: 1655 GKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEEL 1714
Query: 425 LRREQEEERHEQKHEQ-ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD---- 479
R ++E QK ++ E +++ E E R EE R E+ KQ+L+ +
Sbjct: 1715 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1774
Query: 480 -------------QEEERRERWLKLEEEERREQQERR-----------------EQQLRR 509
EE +R+R L E+ R+ + R E ++
Sbjct: 1775 RELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL 1834
Query: 510 EQEERREQRLKRQEEEERLQQRLRSEQ--QLRREQEERREQLLKR-----EEEKRLEQER 562
+++E +RL+R E+E Q+R EQ Q + + EER QL K E +K L ++
Sbjct: 1835 KEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDT 1894
Query: 563 REQRLKREQE---------------------------ERRDQLLKREEER---------- 585
QR + E+E D L +E+
Sbjct: 1895 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1954
Query: 586 -RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
++R +RE EER+++ L EE E Q + + ++R + + E ++L + EQE RQ
Sbjct: 1955 AEEERRRREAEERVQKSLAAEE-EAARQRKAALEEVERLKAKVEEARRLRERAEQESARQ 2013
Query: 645 QQLRREQQERREQRLKR------EEEEERLEQRLKREH---EEERREQELAE---EEQEQ 692
QL +E ++R Q ++ +++E+ L+Q L++E ++ R E E A EE E+
Sbjct: 2014 LQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2073
Query: 693 ARERIKSRIPKWQWQLESEADARQS---KVYSRPRKQ---EGQRRRQEQEEKRRRRESEL 746
AR + + + + Q+E +QS + +R + Q E R+ EQE RR + +
Sbjct: 2074 ARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQA 2133
Query: 747 QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA-----RPPLREQRERQLRAE 801
++++ A + ++ ++ + T + +A+ + E RL + L ++ ++L+AE
Sbjct: 2134 ALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2193
Query: 802 ERQQREQRFLPEEE--------EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
+ QR EEE E+ + + R E E L +++ QR LQEE
Sbjct: 2194 ATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR-----FLQEEA 2248
Query: 854 DGLQE--DQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEE 911
+ +++ ++ R S + + R EE+ ++R AL E++ KE+ +E
Sbjct: 2249 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQR-------ALAEKMLKEKMQAVQEAT 2301
Query: 912 ELQRE----EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967
L+ E +++K QEQ R+ +E++ +Q +QL E + +R E ERQ + + +
Sbjct: 2302 RLKAEAELLQQQKELAQEQARRLQEDK--EQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2359
Query: 968 QKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR----QEWERQYRKK 1023
+ +L E + + + E R ++ ++ E+L R E + + Q E Q ++
Sbjct: 2360 AERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2419
Query: 1024 D-ELQQEEEQLLREEREKRRLQERER--QYREEEELQQEEEQLLGEERETRRR--QELER 1078
D + ++ E + EREK +LQ+ + Q + EE ++EQLL E + ++ E +
Sbjct: 2420 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDS 2479
Query: 1079 QYRKEEELQQEE---EQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135
++E ++QE+ EQL ++E K +Q RE Q R++++++QE ++L+ E RR
Sbjct: 2480 LLQRERFIEQEKAKLEQLFQDEVAK-AQQLREEQQRQQQQMEQERQRLVASMEEARR--- 2535
Query: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
RQ+ EE V++++E+L Q+LE+Q R++EEL EE Q LRE+ + ++
Sbjct: 2536 --RQHEAEEGVRRKQEEL----------QQLEQQRRQQEELLAEENQRLREQLQLLEEQH 2583
Query: 1196 ERQYREEEEL 1205
EE+
Sbjct: 2584 RAALAHSEEV 2593
Score = 212 bits (539), Expect = 3e-54
Identities = 221/808 (27%), Positives = 387/808 (47%), Gaps = 87/808 (10%)
Query: 88 ALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRR--QKRQEQE 145
A+G+AT L E KE+ + R+ + F+ R+LEE+ Q + ++R Q
Sbjct: 1819 AIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQ--RRRLEEQAAQHKADIEERLAQL 1876
Query: 146 RELAEGEEQSEKQERLEQRDRQRR--DEELWRQRQEWQEREERRAE-EEQLQSCKGHETE 202
R+ ++ E + +K +E RQRR +EE+ + +++ +AE E +L + +
Sbjct: 1877 RKASDSELERQK-GLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA-- 1933
Query: 203 EFPDEEQLRRRELLEL----RRKGREEKQQQRRERQDRVFQE--EEEKEWRKRETVLRKE 256
E+ LR +E EL +R+ E++++RRE ++RV + EE+ R+R+ L +
Sbjct: 1934 ----EDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 1989
Query: 257 EE-KLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL---RREQQLRRKQEE 312
E K + EE +R RE E+E + QE ++R + E++ ++EQ+L++ ++
Sbjct: 1990 ERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQ 2049
Query: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER 372
E+ + R E + R EE E R Q ER Q RR+ EE R +Q EQ + R
Sbjct: 2050 EQSVLDQLRGEAEAARRAAEEAEE---ARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2106
Query: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLR----------REQQLRREQQLRRE 422
+ Q E +LR+E + ++ + EQ R++Q EQ LR++ Q+ +E
Sbjct: 2107 AQAQAAAE-KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQE 2165
Query: 423 QQLRREQEEERHEQKHEQERREQRLKREQEE---RRDWLKREEETERHEQERRKQQLKRD 479
R Q EE QK+ + QRLK E E +R ++ E + R + E + R
Sbjct: 2166 LTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2225
Query: 480 QEEER------RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
+ E R ++ + +EE + ++ E+ R + RL++ EE+ QQR
Sbjct: 2226 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2285
Query: 534 SEQQLRREQEERRE--------QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585
+E+ L+ + + +E +LL++++E EQ RR Q E +E+ Q L E +
Sbjct: 2286 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ----EDKEQMAQQLAEETQG 2341
Query: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ 645
Q+ L+ E++ +LE + E ++ E R Q E+ + R+Q E E+ +
Sbjct: 2342 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ---AEEIGEKLHRT 2398
Query: 646 QLRREQQERREQRLK-REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKW 704
+L +++ Q L+ + ++ + +RL+ E RE+E ++E + + + +
Sbjct: 2399 ELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQ 2458
Query: 705 QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR 764
Q QL E A Q S + R EQE+ + Q ++E A QQ EEQ+
Sbjct: 2459 QEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE-----QLFQDEVAKAQQLREEQQ 2513
Query: 765 RDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQR 824
R +++ E+ RQRL A + E R RQ AEE +R+Q EE +Q +QR
Sbjct: 2514 RQ-------QQQMEQERQRLVA--SMEEARRRQHEAEEGVRRKQ------EELQQLEQQR 2558
Query: 825 REREKELQFLEEEEQLQRRERAQQLQEE 852
R++E+ L EE + RE+ Q L+E+
Sbjct: 2559 RQQEE----LLAEENQRLREQLQLLEEQ 2582
Score = 151 bits (382), Expect = 5e-36
Identities = 162/632 (25%), Positives = 294/632 (46%), Gaps = 80/632 (12%)
Query: 99 KRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQ-----------ERE 147
+RA + +E+ +Q R+ RR Q+EE +R +Q +EQ E+
Sbjct: 2065 RRAAEEAEEARVQAEREAAQSRR------QVEE--AERLKQSAEEQAQARAQAQAAAEKL 2116
Query: 148 LAEGEEQSEKQERLEQ---RDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
E E+++ ++ + EQ R +Q D E+ + ++ ++ ++A+ EQ + + EE
Sbjct: 2117 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2176
Query: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQD----RVFQEEEEK-----EWRKRETVLRK 255
++ L EL L+ + E +Q+ + ++ RV EE K E R +LR
Sbjct: 2177 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD 2236
Query: 256 EE--EKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ--EEEQQQQRLRREQQLRRK-- 309
++ ++ +EE ++ +++ EE +L + QE R RQ EE+ QQR E+ L+ K
Sbjct: 2237 KDNTQRFLQEEAEKMKQVAEEAARL-SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQ 2295
Query: 310 --QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE------EERRE 361
QE R + + E +QQ+ Q++ RR Q E +E+ QQL E + E R+
Sbjct: 2296 AVQEATRLKAEAELLQQQKELAQEQARRLQ----EDKEQMAQQLAEETQGFQRTLEAERQ 2351
Query: 362 QQLRREQEEER---REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
+QL E ER R ++ R Q E R +Q + +L ++++ Q
Sbjct: 2352 RQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT 2411
Query: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR 478
L ++Q E E E ER +++L Q+E + + EE + +QE+ Q+ +
Sbjct: 2412 LEIQRQQSDHDAERLREAIAELEREKEKL---QQEAKLLQLKSEEMQTVQQEQLLQETQA 2468
Query: 479 DQEEERRERWLKLEEEERREQQERREQQL-----RREQEERREQRLKRQEEEERLQQRLR 533
Q+ E+ L+ E EQ++ + +QL + Q+ R EQ+ ++Q+ E+ Q+ +
Sbjct: 2469 LQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVA 2528
Query: 534 SEQQLRREQEERREQLLKREEE-KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592
S ++ RR Q E E + +++EE ++LEQ+RR+Q ++LL E +R +++L+
Sbjct: 2529 SMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ----------EELLAEENQRLREQLQL 2578
Query: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRRE-- 650
+E+ EEV + + R+ + +E + E LRR+
Sbjct: 2579 LEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGP------AAEAEPEHSFDGLRRKVS 2632
Query: 651 QQERREQRLKREEEEERLEQRLKREHEEERRE 682
Q +E + EE +RL Q E RRE
Sbjct: 2633 AQRLQEAGILSAEELQRLAQGHTTVDELARRE 2664
Score = 96.3 bits (238), Expect = 3e-19
Identities = 86/335 (25%), Positives = 166/335 (49%), Gaps = 42/335 (12%)
Query: 80 KVAQACYYALGQATGLDEEKRARCDGKESLLQDRR------QEEDQRRFEPRDRQLEEEP 133
K+ Q A + E R R +E L Q R +E+ Q E + E E
Sbjct: 2250 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAEL 2309
Query: 134 GQRRRQKRQEQERELAEGEEQSEKQ--------ERLEQRDRQRRDE-----ELWRQRQEW 180
Q++++ QEQ R L E +EQ +Q +R + +RQR+ E E + R
Sbjct: 2310 LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAE 2369
Query: 181 QEREERRAEEEQLQSCKGHET-------EEFPDEEQLRRRELLELRRKGREEKQQQRRE- 232
R + RAEE+ + K E E +E++ + LE++R+ + ++ RE
Sbjct: 2370 MSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREA 2429
Query: 233 ------RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRK---LER 283
++++ QE + + + E ++E+ LQE + +Q L E++ L++ +E+
Sbjct: 2430 IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQ 2489
Query: 284 QELRRER--QEEEQQQQRLRREQQLRRKQEEERREQ----QEERREQQERREQQEERREQ 337
++ + E+ Q+E + Q+LR EQQ +++Q E+ R++ EE R +Q E+ R+++
Sbjct: 2490 EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQE 2549
Query: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEER 372
+L++ +++RR+Q+ +E +R +QL+ +E+ R
Sbjct: 2550 ELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHR 2584
Score = 37.4 bits (85), Expect = 0.14
Identities = 73/313 (23%), Positives = 122/313 (38%), Gaps = 57/313 (18%)
Query: 933 EEQLQQEEEQLLREEREKRRRQER----ERQYRKDKKLQQKEEQLL--GEEPEKRRRQER 986
E+QL+ E E+L +R + Q E Q + L Q + +LL G+ P++ ER
Sbjct: 359 EKQLRSEFERLECLQRIVTKLQMEAGLCEEQLNQADALLQSDVRLLAAGKVPQRAGEVER 418
Query: 987 E-KKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ-EEEQLLR--------- 1035
+ K L + Q L++ R + Q + R YR + L E LR
Sbjct: 419 DLDKADSMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPA 478
Query: 1036 EEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE----------LERQYRKEEE 1085
+ + LQ +R+ E+ + + LL E + R + +E Q
Sbjct: 479 TQVAQVTLQSVQRRPELEDSTLRYLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRG 538
Query: 1086 LQQEEEQLLREEPEKRRRQERE---------RQCREEEELQQEEEQLLREEREKRRRQEL 1136
L Q E+ R + E+ R E + R C +LQ + LL + + R E
Sbjct: 539 LHQSIEEF-RAKIERARSDEGQLSPATRGAYRDCLGRLDLQYAK--LLNSSKARLRSLES 595
Query: 1137 ERQY-------------REEEEV-----QQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178
+ +EEEEV + ++E +ELE + ++ +ELQ
Sbjct: 596 LHSFVAAATKELMWLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQN 655
Query: 1179 EEEQLLREEQEKR 1191
++LLRE+ R
Sbjct: 656 AGDRLLREDHPAR 668
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 342 bits (876), Expect = 3e-93
Identities = 446/1785 (24%), Positives = 774/1785 (43%), Gaps = 216/1785 (12%)
Query: 114 RQEEDQRRFEPRDRQL-EEEPG----------QRRRQKRQEQER------ELAEGEEQSE 156
R +D F P DR + E E G Q Q QE+ R EL + Q E
Sbjct: 924 RDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGAQEESRCQRCISELKDIRLQLE 983
Query: 157 KQE-RLEQRDRQRRDEELWRQ-RQEWQEREERRAEEEQL------QSCKGHETEEFPDEE 208
E R R R D+E R+ Q E+++ +AE E L S + + P+
Sbjct: 984 ACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPS 1043
Query: 209 QL--RRRELLELRRKGREEKQQQRRERQDRVFQEEEE------KEWRKRETVLRKEEEKL 260
R LEL E+ + ++ E+ + + + E VLR EE+L
Sbjct: 1044 PAAPTLRSELELTLGKLEQVRS-----LSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQL 1098
Query: 261 QEEE--PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318
+E + P EL+ + L+KL R + ++ + + LR Q++ + ++ E+
Sbjct: 1099 KEAQAVPATLPELEATKASLKKL-RAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERD 1157
Query: 319 EERREQQERREQQEERREQQLRREQEERRE-QQLRREQEEERRE-QQLRREQEEERREQQ 376
E +ER Q ER + L + +RE +QL R+ R L ++ RR Q+
Sbjct: 1158 VEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQE 1217
Query: 377 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE---- 432
+ L Q +R +QLR+EQ L E + R + E Q +Q + ++ E
Sbjct: 1218 QIQAMPLADSQAVR--EQLRQEQALLEE--IERHGEKVEECQRFAKQYINAIKDYELQLV 1273
Query: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR----------KQQLKRDQEE 482
++ + E + + Q ++ + H E + L+R +EE
Sbjct: 1274 TYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEE 1333
Query: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
ER + EE ER + E ++ R+ E + + + + E + LQQR++ E+ +RRE+
Sbjct: 1334 ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ-EEVVRREE 1392
Query: 543 EERREQLLKREEEKRLEQERRE-----QRLKREQEERRDQLLKREEERRQQRLKREQEER 597
Q KR ++ L+Q R+ Q R+ E L+ EEE R RL+ E ER
Sbjct: 1393 AAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATER 1452
Query: 598 -----------LEQRLKREEVERLEQEERREQRLKREEPEEERRQQ----LLKSEEQEER 642
L R + E ++ + +E E+ ++ + E +R++Q L + E
Sbjct: 1453 QRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAE 1512
Query: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIP 702
++ +R Q E RL+ EE E RL Q E E R+ Q E Q A ++S+
Sbjct: 1513 AAREKQRALQALEELRLQAEEAERRLRQ---AEVERARQVQVALETAQRSAEAELQSKRA 1569
Query: 703 KW-QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES---ELQ-WQ---EEERA 754
+ + + E ++ V ++E +RR Q+Q E R RE EL+ WQ E
Sbjct: 1570 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1629
Query: 755 HRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE- 813
R Q EE ++ Q +AE++ E + R EQ RQ E++ +QR L E
Sbjct: 1630 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEG 1689
Query: 814 --------EEEKEQRRRQRREREKELQFLEEE-EQLQRR-----ERAQQLQEEEDGLQED 859
E+E + R + + E++ Q LEEE +LQR ++ Q+L+ E ++ +
Sbjct: 1690 TAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAE 1749
Query: 860 QE-----RRRSQEQRR--DQKWRWQLEEERKRRRHTLYAKP---ALQEQLRKEQQLLQEE 909
E + R++E+ R +K + +LE E R R AL E+ ++++Q L EE
Sbjct: 1750 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQ-LAEE 1808
Query: 910 EEELQREEREK-------------RRRQEQERQYREEEQLQQEEEQLLREEREKRRR--- 953
+ QR E E+ R + E E +E+E + +L +E +RRR
Sbjct: 1809 DAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEE 1868
Query: 954 ---------QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
+ER Q RK + + ++ L E+ ++RRQ E+ + ++
Sbjct: 1869 QAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKA 1928
Query: 1005 REEREKRR-RQEWERQYRKKD--ELQQEEEQLLREEREKRRLQERERQYR----EEEELQ 1057
E E R R E R K+ EL+ ++ L E E+RR + ER + EEE +
Sbjct: 1929 ELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR 1988
Query: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117
Q + L ER + +E R + E+ + QL +E +KR + E + ++ +
Sbjct: 1989 QRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 2048
Query: 1118 QEEEQLLREERE--KRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175
QE +Q L++E+ + R E E R EE ++ Q RE + R RQ E E
Sbjct: 2049 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR------RQVEEAER 2102
Query: 1176 LQQE-EEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234
L+Q EEQ Q + E+ R+ E+E +R + +Q + Q +D E EK
Sbjct: 2103 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADA----EMEKHKK 2158
Query: 1235 VRDNKVYCKGRENEQFR----QLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRD 1290
+ + K + ++ QLE++ + ++LQ L E E R++ + +
Sbjct: 2159 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2218
Query: 1291 RHFPEEEQLEREEQKEAKRRD---RKSQEEKQLLREEREEKRRRQETDRKF----REEEQ 1343
EE + + + EA+ R R ++ L+EE E+ ++ E + +E +
Sbjct: 2219 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2278
Query: 1344 LLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQE 1403
L Q EE +++ K +E+++ ++ + E + L++Q K L +EQ R QE
Sbjct: 2279 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQ----KELAQEQARRLQE 2334
Query: 1404 REQQLRQDRDRKF----------REEEQQLSRQERDRKFREEEQ---QVRRQERERKFLE 1450
++Q+ Q + R+ + ++S + K R E Q R +E ++F +
Sbjct: 2335 DKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRK 2394
Query: 1451 EEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE--- 1507
+ +++ ++ HR ++ + + ++ RQ+ D + + ER+++ +QE
Sbjct: 2395 QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKL 2454
Query: 1508 LRSQEPERKFLEEEQQLHRQQR-QRKFLQEEQQLRRQERG-QQRRQDRDRKFREE----E 1561
L+ + E + +++EQ L Q Q+ FL E+ L ++ER +Q + ++ F++E +
Sbjct: 2455 LQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQ 2514
Query: 1562 QLRQERE-EQQLSRQERDRKFRLEEQKVRRQ----EQERKFMEDEQQLRRQEGQQ-QLRQ 1615
QLR+E++ +QQ QER R E+ RRQ E R+ E+ QQL +Q QQ +L
Sbjct: 2515 QLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLA 2574
Query: 1616 ERDRKFREDEQLLQEREEQQLHRQER--------DRKFLEEEPQLRRQEREQQLRHDRDR 1667
E +++ RE QLL+E+ L E + L E + H D
Sbjct: 2575 EENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDG 2634
Query: 1668 KFRE-EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ 1711
R+ Q LQE +R + +L R+E R +LQ
Sbjct: 2635 LRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQ 2679
Score = 326 bits (836), Expect = 1e-88
Identities = 360/1355 (26%), Positives = 617/1355 (45%), Gaps = 193/1355 (14%)
Query: 113 RRQEEDQR-----RFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQ 167
RR EE++R R E R+R E E E++R+LAE Q++ Q E ++ Q
Sbjct: 1328 RRMEEEERLAEQQRAEERERLAEVEAA-------LEKQRQLAEAHAQAKAQAEREAKELQ 1380
Query: 168 RR--DEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE- 224
+R +E + R+ ++++R+ +E+LQ QLR+ E++ K R+
Sbjct: 1381 QRMQEEVVRREEAAVDAQQQKRSIQEELQ--------------QLRQSSEAEIQAKARQA 1426
Query: 225 ---EKQQQRRERQDRVFQEEEEKEWRKR---ETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
E+ + R E + RV + + E R+R E L+ + +E E Q+ R+ QEE E+L
Sbjct: 1427 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK-RQAQEEAERL 1485
Query: 279 RKLERQELRRERQEEEQQQQRLRREQQLRRKQE------EERREQQEERREQQERREQQE 332
R+ + E +R+RQ E + R++ E + R+++ EE R Q EE E++ R+ + E
Sbjct: 1486 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE-AERRLRQAEVE 1544
Query: 333 ERREQQLRREQEER---REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
R+ Q+ E +R E Q +R E+ Q R QEE QLR E + R +QQ
Sbjct: 1545 RARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQA 1604
Query: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
E+ ++ QL+ + LR Q Q + + E +QK E ER +R +
Sbjct: 1605 EAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGK 1664
Query: 450 EQEE---RRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506
+E+ +R+ ++E E +R E QQ ++E R L+ E E+ +Q++ E++
Sbjct: 1665 AEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR---LRAETEQGEQQRQLLEEE 1721
Query: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566
L R Q E KRQE E L ++R E E + EEE R E+ +QR
Sbjct: 1722 LARLQREAAAATQKRQELEAEL-------AKVRAEMEVLLASKARAEEESRSTSEKSKQR 1774
Query: 567 LKRE------------------QEERRDQLLKREEERRQQ------------------RL 590
L+ E +E +R + L E+ RQ+ RL
Sbjct: 1775 LEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRL 1834
Query: 591 KREQEERL-EQRLKREEVERLEQEERREQRLKREEPE------EERRQQLLKSEEQEERR 643
K E E L E+ + E + RL ++E ++R E+ EER QL K+ + E R
Sbjct: 1835 KTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELER 1894
Query: 644 QQQL------RREQQERREQRLK--------------------REEEEERLEQRLKREHE 677
Q+ L +R Q E LK R E+ L + + E E
Sbjct: 1895 QKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELE 1954
Query: 678 EERREQELAEEE--QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQ 735
R+ Q AEEE + +A ER++ + + + + A +V K E RR +E+
Sbjct: 1955 AARQRQLAAEEERRRREAEERVQKSLAA-EEEAARQRKAALEEVERLKAKVEEARRLRER 2013
Query: 736 EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRE 795
E+ R+ +L +E A ++ Q EE+ F Q + +E + +Q S LR + E
Sbjct: 2014 AEQESARQLQL---AQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2070
Query: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDG 855
RA E + E+ + E E Q RRQ E E+ Q EEQ Q R +AQ E+
Sbjct: 2071 AARRAAE--EAEEARVQAEREAAQSRRQVEEAERLKQ--SAEEQAQARAQAQAAAEKLRK 2126
Query: 856 LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL----LQEEEE 911
E + RR+Q ++ + + + E + +H +A+ L+++ + EQ+L LQ EE
Sbjct: 2127 EAEQEAARRAQAEQAALRQKQAADAEME--KHKKFAEQTLRQKAQVEQELTTLRLQLEET 2184
Query: 912 ELQR---EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
+ Q+ +E +R + E R+ Q+++E + + E + + R + L+
Sbjct: 2185 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD 2244
Query: 969 KE--EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
K+ ++ L EE EK ++ E + + L EE ++R E+ ++K +
Sbjct: 2245 KDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQA 2304
Query: 1027 QQEEEQLLRE----EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK 1082
QE +L E +++K QE+ R+ +E++E Q +QL E + +R E ERQ +
Sbjct: 2305 VQEATRLKAEAELLQQQKELAQEQARRLQEDKE--QMAQQLAEETQGFQRTLEAERQ--R 2360
Query: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYRE 1142
+ E+ E E+L E R Q R EE+ Q+ +Q E EK R EL Q +
Sbjct: 2361 QLEMSAEAERLKLRVAEMSR-----AQARAEEDAQRFRKQ-AEEIGEKLHRTELATQEKV 2414
Query: 1143 EEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREE 1202
E ++ + +R R+ + RE+E+LQQE + L + +E + ++E+ +E
Sbjct: 2415 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQET 2474
Query: 1203 EELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQ 1262
+ LQ Q + E + S L+ + E+E A + + + +Q R E+ Q + +Q
Sbjct: 2475 QALQ-----QSFLSE-KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR--EEQQRQQQQ 2526
Query: 1263 SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR 1322
+Q+ Q L+ +E R Q E E+ R +Q+E ++ +++ +++++LL
Sbjct: 2527 MEQERQRLVASMEEARRRQH------------EAEEGVRRKQEELQQLEQQRRQQEELLA 2574
Query: 1323 EEREEKRRRQETDRKFREEEQLLQEREEQPLRRQE 1357
EE +++ RE+ QLL+E+ L E
Sbjct: 2575 EE----------NQRLREQLQLLEEQHRAALAHSE 2599
Score = 324 bits (830), Expect = 6e-88
Identities = 461/1845 (24%), Positives = 811/1845 (43%), Gaps = 259/1845 (14%)
Query: 253 LRKEEEK--LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQ 310
L+ EE++ L E Q L++ ++ L ER+ + Q L +
Sbjct: 903 LKPEEQRQALHSLELHYQAFLRDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGA 962
Query: 311 EEERREQQ--EERREQQERREQQEERREQQLR--------REQEERREQQLRREQEEERR 360
+EE R Q+ E ++ + + E E R +LR RE +R +Q + + E E
Sbjct: 963 QEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGL 1022
Query: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
+ + R E E+ L + LR E +L L + +Q+R + E+
Sbjct: 1023 GKGVARLSAEA--EKVLALPEPSPAAPTLRSELELT----LGKLEQVRSLSAIYLEKLKT 1076
Query: 421 REQQLRREQEEERHEQKHEQERREQRLKR----EQEERRDWLKR---EEETERHEQERRK 473
+R Q E + HE++ +E + E E + LK+ + E ++ + +
Sbjct: 1077 ISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALR 1136
Query: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
+L+ QE R + E + E+ R QL + Q RQ E E+L ++LR
Sbjct: 1137 DELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLR 1196
Query: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE 593
+ E + L ++ R QE+ + + + R+QL R+E+ + ++R
Sbjct: 1197 YYR-------ESADPLGAWLQDARRRQEQIQAMPLADSQAVREQL--RQEQALLEEIERH 1247
Query: 594 QEERLE-QRLKREEVERLEQEERREQRLKRE-EP--EEERRQQLLKSEEQEERRQQQLRR 649
E+ E QR ++ + ++ E + K + EP ++ ++ E + LR
Sbjct: 1248 GEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRT 1307
Query: 650 EQQERR----------EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
E + L+R EEEERL ++ + E E E E A E+Q Q
Sbjct: 1308 HYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQL------ 1361
Query: 700 RIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQ- 758
+EA A+ R K+ QR QEE RR E+ + Q+++R+ +++
Sbjct: 1362 ----------AEAHAQAKAQAEREAKELQQRM---QEEVVRREEAAVDAQQQKRSIQEEL 1408
Query: 759 QEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQ-----REQRFLPE 813
Q+ Q + Q +A + R RL +R R QL A ERQ+ Q
Sbjct: 1409 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVR-LQLEATERQRGGAEGELQALRAR 1467
Query: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRR----ERAQQLQEEEDGLQEDQERRRSQEQR 869
EE E ++RQ +E + L+ ++E ++R E A +++ E + +E Q ++ E+
Sbjct: 1468 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1527
Query: 870 RDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQ 929
R Q EE +R R A E+ R+ Q L+ + + E + KR E+
Sbjct: 1528 R-----LQAEEAERRLRQ------AEVERARQVQVALETAQRSAEAELQSKRA-SFAEKT 1575
Query: 930 YREEEQLQQEEEQL--LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE 987
+ E LQ+E + LREE E+R +Q+ E + +++ ++ E L R R + E
Sbjct: 1576 AQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE 1635
Query: 988 KKYREEEELQQEEEQLLRE-EREKRRRQEWERQYRKKDELQQEE------------EQLL 1034
+ +++ Q E E+ E ERE RRR + E Q ++ EL ++E +Q L
Sbjct: 1636 EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRL 1695
Query: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERE--TRRRQELERQYRKEEELQQEEEQ 1092
E+E RL+ Q ++ +L +EE L E T++RQELE + K ++ E E
Sbjct: 1696 AAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK---VRAEMEV 1752
Query: 1093 LL----REEPEKRRRQERERQCREEE-----ELQQEEEQL--LREEREKRRR---QELER 1138
LL R E E R E+ +Q E E EL +E +L L EE +++R+ ++ R
Sbjct: 1753 LLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAAR 1812
Query: 1139 QYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE--QEKRRQERE 1196
Q E E V E+ + E R + E E +E+E + +L +E Q +R +E+
Sbjct: 1813 QRAEAERVLAEKLAAIGEAT--RLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQA 1870
Query: 1197 RQYREE-EELQRQKRK----QRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFR 1251
Q++ + EE Q RK + R + D Q +E + + K +
Sbjct: 1871 AQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAEL 1930
Query: 1252 QLEDSQLRDR-----QSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE 1306
+LE ++R +S++ + Q++ E+ERRR + +R ++ L EE E
Sbjct: 1931 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER---VQKSLAAEE--E 1985
Query: 1307 AKRRDRKSQEEKQLLREEREEKRR-RQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365
A R+ + + EE + L+ + EE RR R+ +++ + QL QE ++ L+ +E+ F +
Sbjct: 1986 AARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ 2045
Query: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425
+ + Q + L++EQ + Q R + E R E ++ R +R+ + +Q+
Sbjct: 2046 QKEQELQ--QTLQQEQSVLDQLRG----EAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2099
Query: 1426 QERDRKFREEEQQVR--------------RQERERKFLEEEQQLRQ--------ERHRKF 1463
ER ++ EE+ Q R QE R+ E+ LRQ E+H+KF
Sbjct: 2100 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2159
Query: 1464 REEEQLLQEREEQ-------QLHRQERDRKFLEEEQQLRRQE-----RDRKFREQELRSQ 1511
E+ + + EQ QL + + L+EE Q + E R R E+EL S
Sbjct: 2160 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2219
Query: 1512 EPERKFLEEEQQLHRQQRQRKFLQEEQQLRR--QERGQQRRQDRDRKFR------EEEQL 1563
+ + L + + + + L+++ +R QE ++ +Q + R E +L
Sbjct: 2220 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2279
Query: 1564 RQEREE---QQLSRQERDRKFR----------------LEEQKVRRQEQERKFMEDEQQL 1604
RQ EE QQ + E+ K + L++QK QEQ R+ ED++Q+
Sbjct: 2280 RQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQM 2339
Query: 1605 RRQEGQQQLRQERDRKFREDEQLLQEREEQQLH----RQERDRKFLEEEPQLRRQEREQ- 1659
+Q ++ +R + QL E ++L R + EE+ Q R++ E+
Sbjct: 2340 AQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2399
Query: 1660 -QLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQ---Q 1715
+ H + +E+ L+Q E ++RQ+ D + + ERE++ LQ+E Q
Sbjct: 2400 GEKLHRTELATQEKVTLVQTLE---IQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2456
Query: 1716 LRRQELERKFREEEQLRQET---------EQEQLRRQERYRKILEEEQLRPE---REEQQ 1763
L+ +E++ ++EQL QET E++ L ++ER+ +E+E+ + E ++E
Sbjct: 2457 LKSEEMQTV--QQEQLLQETQALQQSFLSEKDSLLQRERF---IEQEKAKLEQLFQDEVA 2511
Query: 1764 LRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE-EEQLRQEREE-QQLRPQQRDGKY 1821
+Q R+ + R+++Q+ QER+ +E+ R+ E EE +R+++EE QQL Q+R +
Sbjct: 2512 KAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEE 2571
Query: 1822 RWEEEQLQLEEQEQRL-RQERDRQYRAEEQFATQEKSRR-------------EEQELWQE 1867
EE +L EQ Q L Q R +EE A+Q + + E E
Sbjct: 2572 LLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHS 2631
Query: 1868 EEQKRRQERERKLREEHI---RRQQKEEQRHRQVGEIKSQEGKGH 1909
+ RR+ ++L+E I Q+ Q H V E+ +E H
Sbjct: 2632 FDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRH 2676
Score = 321 bits (822), Expect = 5e-87
Identities = 452/1778 (25%), Positives = 777/1778 (43%), Gaps = 303/1778 (17%)
Query: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ--LRREQQL-----------RR 421
Q LRR+ QL R L + L+ E+Q + L Q LR Q R
Sbjct: 883 QSLRRDVQLIRSWSLATFRTLKPEEQRQALHSLELHYQAFLRDSQDAGGFGPEDRLMAER 942
Query: 422 E------------QQLRREQEEERHEQKHEQERREQRLKREQEERRDW----LKREEETE 465
E Q L + +EE Q+ E ++ RL+ E E R L ++E
Sbjct: 943 EYGSCSHHYQQLLQSLEQGAQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPA 1002
Query: 466 RHEQERRKQQLKRDQEEE-----------RRERWLKLEEEERREQQERREQQLRREQ-EE 513
R +R +Q K E E E+ L L E R E +L + E+
Sbjct: 1003 RECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQ 1062
Query: 514 RREQRLKRQEEEERLQQRLR----SEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
R E+ + + +R +E+ LR +E+ +E LE + + R
Sbjct: 1063 VRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLR 1122
Query: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER 629
Q E + + R + R +E ERL+QR +VE ER Q L ER
Sbjct: 1123 AQAEAQQPTF--DALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLL-------ER 1173
Query: 630 RQQLLKSEEQEERRQQQLRREQQERRE---------QRLKREEEE---------ERLEQR 671
Q +L + +R +QL R+ + RE Q +R +E+ + + ++
Sbjct: 1174 WQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQ 1233
Query: 672 LKREH---EEERREQELAEEEQEQARERIKS------RIPKWQWQLESEADARQSKVYSR 722
L++E EE R E EE Q A++ I + ++ ++ QLE A + +
Sbjct: 1234 LRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK-----K 1288
Query: 723 PRKQEGQRRRQEQEEKRRRRESEL----------------QWQEEERAHRQQQEEEQRRD 766
P+ Q G ++ R SEL + +EEER QQ+ EE+ R
Sbjct: 1289 PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER- 1347
Query: 767 FTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQR-EQRFLPEEEEKEQRRRQRR 825
+ E E+ RQ A + Q ER+ A+E QQR ++ + EE ++Q+R
Sbjct: 1348 ---LAEVEAALEKQRQLAEAHAQAKAQAERE--AKELQQRMQEEVVRREEAAVDAQQQKR 1402
Query: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR 885
++ELQ L + + + + +A+Q + E + R R +E+ R R QLE ++R
Sbjct: 1403 SIQEELQQLRQSSEAEIQAKARQAEAAE------RSRLRIEEEIRVV--RLQLEATERQR 1454
Query: 886 ---RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQER------------QY 930
L A A E+ +++ QEE E L+R+ +++ +R+ Q
Sbjct: 1455 GGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAA 1514
Query: 931 REEEQLQQ--EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK 988
RE+++ Q EE +L EE E+R RQ + R+ + + ++ E + +R EK
Sbjct: 1515 REKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEK 1574
Query: 989 KYREEEELQQEEEQL--LREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
+ E LQ+E + LREE E+R +Q+ E + R ++E ++E E+ + E RL+ +
Sbjct: 1575 TAQLERSLQEEHVAVAQLREEAERRAQQQAEAE-RAREEAERELERWQLKANEALRLRLQ 1633
Query: 1047 ERQYREEEELQQEEEQLLGEE--RETRRRQELERQYRKEEELQQEE----EQLLREEPEK 1100
+ +++ L Q E + EE RE RRR + E Q ++ EL ++E QL ++
Sbjct: 1634 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1693
Query: 1101 RRRQERER-QCREEEELQQEEEQLLREEREK---------RRRQELERQYREEEEVQQEE 1150
R E+E + R E E +++ QLL EE + ++RQELE E +V+ E
Sbjct: 1694 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA---ELAKVRAEM 1750
Query: 1151 EQLL----REEPEKRRRQELERQYREEE-----ELQQEEEQLLREEQEKRRQERERQYRE 1201
E LL R E E R E +Q E E EL +E +L +E +RQ RQ E
Sbjct: 1751 EVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ---RQLAE 1807
Query: 1202 EEELQRQKRKQRYRDEDQRS-DLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQL-- 1258
E+ +++ +R E + + + E E A+++ K ENE+ R+L + +
Sbjct: 1808 EDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKE-----KEAENERLRRLAEDEAFQ 1862
Query: 1259 RDRQSQQDLQH-------LLGEQQERDREQERRRWQQRD----RHFPEEEQLEREEQKEA 1307
R R +Q QH L ++ D E ER++ D R EEE L + E
Sbjct: 1863 RRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEK 1922
Query: 1308 KR-----------RDRKSQEEKQLLREEREEKRRRQ-----ETDRKFREEEQLLQEREEQ 1351
R R + E+ +E+ E + RQ E +R+ RE E ER ++
Sbjct: 1923 AAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE----ERVQK 1978
Query: 1352 PLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR-------------QERERKFLKEEQQ 1398
L +E + R+ L E+ + +EE +RLR QE +K L+ E++
Sbjct: 1979 SLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEK 2038
Query: 1399 LRC---QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ-ERE----RKFLE 1450
Q++EQ+L+Q ++ +Q E R+ EE ++ R Q ERE R+ +E
Sbjct: 2039 AHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2098
Query: 1451 EEQQLRQERHRKFREE-------EQLLQEREEQQLHRQERDRKFLEEEQQLRRQ-ERDRK 1502
E ++L+Q + + E+L +E E++ R + ++ L ++Q + E+ +K
Sbjct: 2099 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2158
Query: 1503 FREQELRSQ-EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561
F EQ LR + + E++ QL Q+ L EE Q + E + RQ R EEE
Sbjct: 2159 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQ---RSQVEEE 2215
Query: 1562 QLRQEREEQQLSRQERDRKFRLEEQK----VRRQEQERKFMEDEQQLRRQEGQQQLRQER 1617
+ ++LS+ K R+E + +R ++ ++F+++E + +Q ++ R
Sbjct: 2216 LFSVRVQMEELSKL----KARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV 2271
Query: 1618 DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQ 1677
+ E +L Q EE ++ K L+E+ Q ++ + + E +LLQ
Sbjct: 2272 AAQ--EAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT----------RLKAEAELLQ 2319
Query: 1678 EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ 1737
+ +E QE+ R+ +E+++Q+ +Q L EE Q ++ LE + + + ++ E E+
Sbjct: 2320 QQKELA---QEQARRLQEDKEQMAQQ------LAEETQGFQRTLEAERQRQLEMSAEAER 2370
Query: 1738 EQLRRQERYRKILEEEQLRPEREEQQLRRQERD--RKFREEEQLRQER----EEQQLRSQ 1791
+LR E R Q R E + Q+ R+Q + K E QE+ + +++ Q
Sbjct: 2371 LKLRVAEMSRA-----QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2425
Query: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYR----- 1846
+SD + E E ++ + QQ + + E++Q +QEQ L++ + Q
Sbjct: 2426 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2485
Query: 1847 ----AEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIK 1902
E+F QEK++ E+ L+Q+E K +Q RE + +RQQ++ ++ RQ
Sbjct: 2486 DSLLQRERFIEQEKAKLEQ--LFQDEVAKAQQLREEQ------QRQQQQMEQERQRLVAS 2537
Query: 1903 SQEGKGHGRLLEPGTHQFASVPVRSSPLYEYIQEQRSQ 1940
+E + E G + + L + Q++R Q
Sbjct: 2538 MEEARRRQHEAEEGVRR------KQEELQQLEQQRRQQ 2569
Score = 311 bits (798), Expect = 3e-84
Identities = 324/1270 (25%), Positives = 597/1270 (47%), Gaps = 197/1270 (15%)
Query: 98 EKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE- 156
+ +A+ + + LQ R QEE RR + ++ + +R Q+ +Q R+ +E E Q++
Sbjct: 1367 QAKAQAEREAKELQQRMQEEVVRR---EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKA 1423
Query: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERR-AEEEQLQSCKGHETEEFPDEEQLRRREL 215
+Q +R R R +EE+ R + + E +R E +LQ+ + EE +++ + E
Sbjct: 1424 RQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRA-RAEEAEAQKRQAQEEA 1482
Query: 216 LELRRKGREEKQQQRR---ERQDRVFQEEEEKEWRKRETVLRKE--------EEKLQEEE 264
LRR+ ++E Q++R+ E RV E E ++R +E E +L++ E
Sbjct: 1483 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1542
Query: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
+R R++Q E ++ EL+ +R ++ +L R Q + RE+ E R +Q
Sbjct: 1543 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1602
Query: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
Q E+ E E++L R Q + E R Q EE +Q+ + E E+++++ RE + R
Sbjct: 1603 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1662
Query: 385 ---REQQLRR----EQQLRREQQLRR---EQQLRREQQLRR----------EQQLRREQQ 424
EQ +R+ EQ+L +++QL +Q+L EQ+L R ++QL E+
Sbjct: 1663 GKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEEL 1722
Query: 425 LRREQEEERHEQKHEQ-ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD---- 479
R ++E QK ++ E +++ E E R EE R E+ KQ+L+ +
Sbjct: 1723 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1782
Query: 480 -------------QEEERRERWLKLEEEERREQQERR-----------------EQQLRR 509
EE +R+R L E+ R+ + R E ++
Sbjct: 1783 RELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL 1842
Query: 510 EQEERREQRLKRQEEEERLQQRLRSEQ--QLRREQEERREQLLKR-----EEEKRLEQER 562
+++E +RL+R E+E Q+R EQ Q + + EER QL K E +K L ++
Sbjct: 1843 KEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDT 1902
Query: 563 REQRLKREQE---------------------------ERRDQLLKREEER---------- 585
QR + E+E D L +E+
Sbjct: 1903 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1962
Query: 586 -RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
++R +RE EER+++ L EE E Q + + ++R + + E ++L + EQE RQ
Sbjct: 1963 AEEERRRREAEERVQKSLAAEE-EAARQRKAALEEVERLKAKVEEARRLRERAEQESARQ 2021
Query: 645 QQLRREQQERREQRLKR------EEEEERLEQRLKREH---EEERREQELAE---EEQEQ 692
QL +E ++R Q ++ +++E+ L+Q L++E ++ R E E A EE E+
Sbjct: 2022 LQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2081
Query: 693 ARERIKSRIPKWQWQLESEADARQS---KVYSRPRKQ---EGQRRRQEQEEKRRRRESEL 746
AR + + + + Q+E +QS + +R + Q E R+ EQE RR + +
Sbjct: 2082 ARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQA 2141
Query: 747 QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA-----RPPLREQRERQLRAE 801
++++ A + ++ ++ + T + +A+ + E RL + L ++ ++L+AE
Sbjct: 2142 ALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2201
Query: 802 ERQQREQRFLPEEE--------EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
+ QR EEE E+ + + R E E L +++ QR LQEE
Sbjct: 2202 ATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR-----FLQEEA 2256
Query: 854 DGLQE--DQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEE 911
+ +++ ++ R S + + R EE+ ++R AL E++ KE+ +E
Sbjct: 2257 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQR-------ALAEKMLKEKMQAVQEAT 2309
Query: 912 ELQRE----EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967
L+ E +++K QEQ R+ +E++ +Q +QL E + +R E ERQ + + +
Sbjct: 2310 RLKAEAELLQQQKELAQEQARRLQEDK--EQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2367
Query: 968 QKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR----QEWERQYRKK 1023
+ +L E + + + E R ++ ++ E+L R E + + Q E Q ++
Sbjct: 2368 AERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2427
Query: 1024 D-ELQQEEEQLLREEREKRRLQERER--QYREEEELQQEEEQLLGEERETRRR--QELER 1078
D + ++ E + EREK +LQ+ + Q + EE ++EQLL E + ++ E +
Sbjct: 2428 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDS 2487
Query: 1079 QYRKEEELQQEE---EQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135
++E ++QE+ EQL ++E K +Q RE Q R++++++QE ++L+ E RR
Sbjct: 2488 LLQRERFIEQEKAKLEQLFQDEVAK-AQQLREEQQRQQQQMEQERQRLVASMEEARR--- 2543
Query: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
RQ+ EE V++++E+L Q+LE+Q R++EEL EE Q LRE+ + ++
Sbjct: 2544 --RQHEAEEGVRRKQEEL----------QQLEQQRRQQEELLAEENQRLREQLQLLEEQH 2591
Query: 1196 ERQYREEEEL 1205
EE+
Sbjct: 2592 RAALAHSEEV 2601
Score = 212 bits (539), Expect = 3e-54
Identities = 221/808 (27%), Positives = 387/808 (47%), Gaps = 87/808 (10%)
Query: 88 ALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRR--QKRQEQE 145
A+G+AT L E KE+ + R+ + F+ R+LEE+ Q + ++R Q
Sbjct: 1827 AIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQ--RRRLEEQAAQHKADIEERLAQL 1884
Query: 146 RELAEGEEQSEKQERLEQRDRQRR--DEELWRQRQEWQEREERRAE-EEQLQSCKGHETE 202
R+ ++ E + +K +E RQRR +EE+ + +++ +AE E +L + +
Sbjct: 1885 RKASDSELERQK-GLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA-- 1941
Query: 203 EFPDEEQLRRRELLEL----RRKGREEKQQQRRERQDRVFQE--EEEKEWRKRETVLRKE 256
E+ LR +E EL +R+ E++++RRE ++RV + EE+ R+R+ L +
Sbjct: 1942 ----EDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 1997
Query: 257 EE-KLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL---RREQQLRRKQEE 312
E K + EE +R RE E+E + QE ++R + E++ ++EQ+L++ ++
Sbjct: 1998 ERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQ 2057
Query: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER 372
E+ + R E + R EE E R Q ER Q RR+ EE R +Q EQ + R
Sbjct: 2058 EQSVLDQLRGEAEAARRAAEEAEE---ARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2114
Query: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLR----------REQQLRREQQLRRE 422
+ Q E +LR+E + ++ + EQ R++Q EQ LR++ Q+ +E
Sbjct: 2115 AQAQAAAE-KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQE 2173
Query: 423 QQLRREQEEERHEQKHEQERREQRLKREQEE---RRDWLKREEETERHEQERRKQQLKRD 479
R Q EE QK+ + QRLK E E +R ++ E + R + E + R
Sbjct: 2174 LTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2233
Query: 480 QEEER------RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
+ E R ++ + +EE + ++ E+ R + RL++ EE+ QQR
Sbjct: 2234 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2293
Query: 534 SEQQLRREQEERRE--------QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585
+E+ L+ + + +E +LL++++E EQ RR Q E +E+ Q L E +
Sbjct: 2294 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ----EDKEQMAQQLAEETQG 2349
Query: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ 645
Q+ L+ E++ +LE + E ++ E R Q E+ + R+Q E E+ +
Sbjct: 2350 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ---AEEIGEKLHRT 2406
Query: 646 QLRREQQERREQRLK-REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKW 704
+L +++ Q L+ + ++ + +RL+ E RE+E ++E + + + +
Sbjct: 2407 ELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQ 2466
Query: 705 QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR 764
Q QL E A Q S + R EQE+ + Q ++E A QQ EEQ+
Sbjct: 2467 QEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE-----QLFQDEVAKAQQLREEQQ 2521
Query: 765 RDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQR 824
R +++ E+ RQRL A + E R RQ AEE +R+Q EE +Q +QR
Sbjct: 2522 RQ-------QQQMEQERQRLVA--SMEEARRRQHEAEEGVRRKQ------EELQQLEQQR 2566
Query: 825 REREKELQFLEEEEQLQRRERAQQLQEE 852
R++E+ L EE + RE+ Q L+E+
Sbjct: 2567 RQQEE----LLAEENQRLREQLQLLEEQ 2590
Score = 151 bits (382), Expect = 5e-36
Identities = 162/632 (25%), Positives = 294/632 (46%), Gaps = 80/632 (12%)
Query: 99 KRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQ-----------ERE 147
+RA + +E+ +Q R+ RR Q+EE +R +Q +EQ E+
Sbjct: 2073 RRAAEEAEEARVQAEREAAQSRR------QVEE--AERLKQSAEEQAQARAQAQAAAEKL 2124
Query: 148 LAEGEEQSEKQERLEQ---RDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
E E+++ ++ + EQ R +Q D E+ + ++ ++ ++A+ EQ + + EE
Sbjct: 2125 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2184
Query: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQD----RVFQEEEEK-----EWRKRETVLRK 255
++ L EL L+ + E +Q+ + ++ RV EE K E R +LR
Sbjct: 2185 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD 2244
Query: 256 EE--EKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ--EEEQQQQRLRREQQLRRK-- 309
++ ++ +EE ++ +++ EE +L + QE R RQ EE+ QQR E+ L+ K
Sbjct: 2245 KDNTQRFLQEEAEKMKQVAEEAARL-SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQ 2303
Query: 310 --QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE------EERRE 361
QE R + + E +QQ+ Q++ RR Q E +E+ QQL E + E R+
Sbjct: 2304 AVQEATRLKAEAELLQQQKELAQEQARRLQ----EDKEQMAQQLAEETQGFQRTLEAERQ 2359
Query: 362 QQLRREQEEER---REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
+QL E ER R ++ R Q E R +Q + +L ++++ Q
Sbjct: 2360 RQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT 2419
Query: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR 478
L ++Q E E E ER +++L Q+E + + EE + +QE+ Q+ +
Sbjct: 2420 LEIQRQQSDHDAERLREAIAELEREKEKL---QQEAKLLQLKSEEMQTVQQEQLLQETQA 2476
Query: 479 DQEEERRERWLKLEEEERREQQERREQQL-----RREQEERREQRLKRQEEEERLQQRLR 533
Q+ E+ L+ E EQ++ + +QL + Q+ R EQ+ ++Q+ E+ Q+ +
Sbjct: 2477 LQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVA 2536
Query: 534 SEQQLRREQEERREQLLKREEE-KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592
S ++ RR Q E E + +++EE ++LEQ+RR+Q ++LL E +R +++L+
Sbjct: 2537 SMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ----------EELLAEENQRLREQLQL 2586
Query: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRRE-- 650
+E+ EEV + + R+ + +E + E LRR+
Sbjct: 2587 LEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGP------AAEAEPEHSFDGLRRKVS 2640
Query: 651 QQERREQRLKREEEEERLEQRLKREHEEERRE 682
Q +E + EE +RL Q E RRE
Sbjct: 2641 AQRLQEAGILSAEELQRLAQGHTTVDELARRE 2672
Score = 96.3 bits (238), Expect = 3e-19
Identities = 86/335 (25%), Positives = 166/335 (49%), Gaps = 42/335 (12%)
Query: 80 KVAQACYYALGQATGLDEEKRARCDGKESLLQDRR------QEEDQRRFEPRDRQLEEEP 133
K+ Q A + E R R +E L Q R +E+ Q E + E E
Sbjct: 2258 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAEL 2317
Query: 134 GQRRRQKRQEQERELAEGEEQSEKQ--------ERLEQRDRQRRDE-----ELWRQRQEW 180
Q++++ QEQ R L E +EQ +Q +R + +RQR+ E E + R
Sbjct: 2318 LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAE 2377
Query: 181 QEREERRAEEEQLQSCKGHET-------EEFPDEEQLRRRELLELRRKGREEKQQQRRE- 232
R + RAEE+ + K E E +E++ + LE++R+ + ++ RE
Sbjct: 2378 MSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREA 2437
Query: 233 ------RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRK---LER 283
++++ QE + + + E ++E+ LQE + +Q L E++ L++ +E+
Sbjct: 2438 IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQ 2497
Query: 284 QELRRER--QEEEQQQQRLRREQQLRRKQEEERREQ----QEERREQQERREQQEERREQ 337
++ + E+ Q+E + Q+LR EQQ +++Q E+ R++ EE R +Q E+ R+++
Sbjct: 2498 EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQE 2557
Query: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEER 372
+L++ +++RR+Q+ +E +R +QL+ +E+ R
Sbjct: 2558 ELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHR 2592
Score = 37.4 bits (85), Expect = 0.14
Identities = 73/313 (23%), Positives = 122/313 (38%), Gaps = 57/313 (18%)
Query: 933 EEQLQQEEEQLLREEREKRRRQER----ERQYRKDKKLQQKEEQLL--GEEPEKRRRQER 986
E+QL+ E E+L +R + Q E Q + L Q + +LL G+ P++ ER
Sbjct: 367 EKQLRSEFERLECLQRIVTKLQMEAGLCEEQLNQADALLQSDVRLLAAGKVPQRAGEVER 426
Query: 987 E-KKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ-EEEQLLR--------- 1035
+ K L + Q L++ R + Q + R YR + L E LR
Sbjct: 427 DLDKADSMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPA 486
Query: 1036 EEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE----------LERQYRKEEE 1085
+ + LQ +R+ E+ + + LL E + R + +E Q
Sbjct: 487 TQVAQVTLQSVQRRPELEDSTLRYLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRG 546
Query: 1086 LQQEEEQLLREEPEKRRRQERE---------RQCREEEELQQEEEQLLREEREKRRRQEL 1136
L Q E+ R + E+ R E + R C +LQ + LL + + R E
Sbjct: 547 LHQSIEEF-RAKIERARSDEGQLSPATRGAYRDCLGRLDLQYAK--LLNSSKARLRSLES 603
Query: 1137 ERQY-------------REEEEV-----QQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178
+ +EEEEV + ++E +ELE + ++ +ELQ
Sbjct: 604 LHSFVAAATKELMWLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQN 663
Query: 1179 EEEQLLREEQEKR 1191
++LLRE+ R
Sbjct: 664 AGDRLLREDHPAR 676
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 342 bits (876), Expect = 3e-93
Identities = 446/1785 (24%), Positives = 774/1785 (43%), Gaps = 216/1785 (12%)
Query: 114 RQEEDQRRFEPRDRQL-EEEPG----------QRRRQKRQEQER------ELAEGEEQSE 156
R +D F P DR + E E G Q Q QE+ R EL + Q E
Sbjct: 965 RDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGAQEESRCQRCISELKDIRLQLE 1024
Query: 157 KQE-RLEQRDRQRRDEELWRQ-RQEWQEREERRAEEEQL------QSCKGHETEEFPDEE 208
E R R R D+E R+ Q E+++ +AE E L S + + P+
Sbjct: 1025 ACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPS 1084
Query: 209 QL--RRRELLELRRKGREEKQQQRRERQDRVFQEEEE------KEWRKRETVLRKEEEKL 260
R LEL E+ + ++ E+ + + + E VLR EE+L
Sbjct: 1085 PAAPTLRSELELTLGKLEQVRS-----LSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQL 1139
Query: 261 QEEE--PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318
+E + P EL+ + L+KL R + ++ + + LR Q++ + ++ E+
Sbjct: 1140 KEAQAVPATLPELEATKASLKKL-RAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERD 1198
Query: 319 EERREQQERREQQEERREQQLRREQEERRE-QQLRREQEEERRE-QQLRREQEEERREQQ 376
E +ER Q ER + L + +RE +QL R+ R L ++ RR Q+
Sbjct: 1199 VEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQE 1258
Query: 377 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE---- 432
+ L Q +R +QLR+EQ L E + R + E Q +Q + ++ E
Sbjct: 1259 QIQAMPLADSQAVR--EQLRQEQALLEE--IERHGEKVEECQRFAKQYINAIKDYELQLV 1314
Query: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR----------KQQLKRDQEE 482
++ + E + + Q ++ + H E + L+R +EE
Sbjct: 1315 TYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEE 1374
Query: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
ER + EE ER + E ++ R+ E + + + + E + LQQR++ E+ +RRE+
Sbjct: 1375 ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ-EEVVRREE 1433
Query: 543 EERREQLLKREEEKRLEQERRE-----QRLKREQEERRDQLLKREEERRQQRLKREQEER 597
Q KR ++ L+Q R+ Q R+ E L+ EEE R RL+ E ER
Sbjct: 1434 AAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATER 1493
Query: 598 -----------LEQRLKREEVERLEQEERREQRLKREEPEEERRQQ----LLKSEEQEER 642
L R + E ++ + +E E+ ++ + E +R++Q L + E
Sbjct: 1494 QRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAE 1553
Query: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIP 702
++ +R Q E RL+ EE E RL Q E E R+ Q E Q A ++S+
Sbjct: 1554 AAREKQRALQALEELRLQAEEAERRLRQ---AEVERARQVQVALETAQRSAEAELQSKRA 1610
Query: 703 KW-QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES---ELQ-WQ---EEERA 754
+ + + E ++ V ++E +RR Q+Q E R RE EL+ WQ E
Sbjct: 1611 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALR 1670
Query: 755 HRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE- 813
R Q EE ++ Q +AE++ E + R EQ RQ E++ +QR L E
Sbjct: 1671 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEG 1730
Query: 814 --------EEEKEQRRRQRREREKELQFLEEE-EQLQRR-----ERAQQLQEEEDGLQED 859
E+E + R + + E++ Q LEEE +LQR ++ Q+L+ E ++ +
Sbjct: 1731 TAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAE 1790
Query: 860 QE-----RRRSQEQRR--DQKWRWQLEEERKRRRHTLYAKP---ALQEQLRKEQQLLQEE 909
E + R++E+ R +K + +LE E R R AL E+ ++++Q L EE
Sbjct: 1791 MEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQ-LAEE 1849
Query: 910 EEELQREEREK-------------RRRQEQERQYREEEQLQQEEEQLLREEREKRRR--- 953
+ QR E E+ R + E E +E+E + +L +E +RRR
Sbjct: 1850 DAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEE 1909
Query: 954 ---------QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
+ER Q RK + + ++ L E+ ++RRQ E+ + ++
Sbjct: 1910 QAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKA 1969
Query: 1005 REEREKRR-RQEWERQYRKKD--ELQQEEEQLLREEREKRRLQERERQYR----EEEELQ 1057
E E R R E R K+ EL+ ++ L E E+RR + ER + EEE +
Sbjct: 1970 ELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR 2029
Query: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117
Q + L ER + +E R + E+ + QL +E +KR + E + ++ +
Sbjct: 2030 QRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKE 2089
Query: 1118 QEEEQLLREERE--KRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175
QE +Q L++E+ + R E E R EE ++ Q RE + R RQ E E
Sbjct: 2090 QELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSR------RQVEEAER 2143
Query: 1176 LQQE-EEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234
L+Q EEQ Q + E+ R+ E+E +R + +Q + Q +D E EK
Sbjct: 2144 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADA----EMEKHKK 2199
Query: 1235 VRDNKVYCKGRENEQFR----QLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRD 1290
+ + K + ++ QLE++ + ++LQ L E E R++ + +
Sbjct: 2200 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2259
Query: 1291 RHFPEEEQLEREEQKEAKRRD---RKSQEEKQLLREEREEKRRRQETDRKF----REEEQ 1343
EE + + + EA+ R R ++ L+EE E+ ++ E + +E +
Sbjct: 2260 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2319
Query: 1344 LLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQE 1403
L Q EE +++ K +E+++ ++ + E + L++Q K L +EQ R QE
Sbjct: 2320 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQ----KELAQEQARRLQE 2375
Query: 1404 REQQLRQDRDRKF----------REEEQQLSRQERDRKFREEEQ---QVRRQERERKFLE 1450
++Q+ Q + R+ + ++S + K R E Q R +E ++F +
Sbjct: 2376 DKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRK 2435
Query: 1451 EEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE--- 1507
+ +++ ++ HR ++ + + ++ RQ+ D + + ER+++ +QE
Sbjct: 2436 QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKL 2495
Query: 1508 LRSQEPERKFLEEEQQLHRQQR-QRKFLQEEQQLRRQERG-QQRRQDRDRKFREE----E 1561
L+ + E + +++EQ L Q Q+ FL E+ L ++ER +Q + ++ F++E +
Sbjct: 2496 LQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQ 2555
Query: 1562 QLRQERE-EQQLSRQERDRKFRLEEQKVRRQ----EQERKFMEDEQQLRRQEGQQ-QLRQ 1615
QLR+E++ +QQ QER R E+ RRQ E R+ E+ QQL +Q QQ +L
Sbjct: 2556 QLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLA 2615
Query: 1616 ERDRKFREDEQLLQEREEQQLHRQER--------DRKFLEEEPQLRRQEREQQLRHDRDR 1667
E +++ RE QLL+E+ L E + L E + H D
Sbjct: 2616 EENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDG 2675
Query: 1668 KFRE-EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ 1711
R+ Q LQE +R + +L R+E R +LQ
Sbjct: 2676 LRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQ 2720
Score = 326 bits (836), Expect = 1e-88
Identities = 360/1355 (26%), Positives = 617/1355 (45%), Gaps = 193/1355 (14%)
Query: 113 RRQEEDQR-----RFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQ 167
RR EE++R R E R+R E E E++R+LAE Q++ Q E ++ Q
Sbjct: 1369 RRMEEEERLAEQQRAEERERLAEVEAA-------LEKQRQLAEAHAQAKAQAEREAKELQ 1421
Query: 168 RR--DEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE- 224
+R +E + R+ ++++R+ +E+LQ QLR+ E++ K R+
Sbjct: 1422 QRMQEEVVRREEAAVDAQQQKRSIQEELQ--------------QLRQSSEAEIQAKARQA 1467
Query: 225 ---EKQQQRRERQDRVFQEEEEKEWRKR---ETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
E+ + R E + RV + + E R+R E L+ + +E E Q+ R+ QEE E+L
Sbjct: 1468 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK-RQAQEEAERL 1526
Query: 279 RKLERQELRRERQEEEQQQQRLRREQQLRRKQE------EERREQQEERREQQERREQQE 332
R+ + E +R+RQ E + R++ E + R+++ EE R Q EE E++ R+ + E
Sbjct: 1527 RRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE-AERRLRQAEVE 1585
Query: 333 ERREQQLRREQEER---REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
R+ Q+ E +R E Q +R E+ Q R QEE QLR E + R +QQ
Sbjct: 1586 RARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQA 1645
Query: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
E+ ++ QL+ + LR Q Q + + E +QK E ER +R +
Sbjct: 1646 EAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGK 1705
Query: 450 EQEE---RRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506
+E+ +R+ ++E E +R E QQ ++E R L+ E E+ +Q++ E++
Sbjct: 1706 AEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIR---LRAETEQGEQQRQLLEEE 1762
Query: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566
L R Q E KRQE E L ++R E E + EEE R E+ +QR
Sbjct: 1763 LARLQREAAAATQKRQELEAEL-------AKVRAEMEVLLASKARAEEESRSTSEKSKQR 1815
Query: 567 LKRE------------------QEERRDQLLKREEERRQQ------------------RL 590
L+ E +E +R + L E+ RQ+ RL
Sbjct: 1816 LEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRL 1875
Query: 591 KREQEERL-EQRLKREEVERLEQEERREQRLKREEPE------EERRQQLLKSEEQEERR 643
K E E L E+ + E + RL ++E ++R E+ EER QL K+ + E R
Sbjct: 1876 KTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELER 1935
Query: 644 QQQL------RREQQERREQRLK--------------------REEEEERLEQRLKREHE 677
Q+ L +R Q E LK R E+ L + + E E
Sbjct: 1936 QKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELE 1995
Query: 678 EERREQELAEEE--QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQ 735
R+ Q AEEE + +A ER++ + + + + A +V K E RR +E+
Sbjct: 1996 AARQRQLAAEEERRRREAEERVQKSLAA-EEEAARQRKAALEEVERLKAKVEEARRLRER 2054
Query: 736 EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRE 795
E+ R+ +L +E A ++ Q EE+ F Q + +E + +Q S LR + E
Sbjct: 2055 AEQESARQLQL---AQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2111
Query: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDG 855
RA E + E+ + E E Q RRQ E E+ Q EEQ Q R +AQ E+
Sbjct: 2112 AARRAAE--EAEEARVQAEREAAQSRRQVEEAERLKQ--SAEEQAQARAQAQAAAEKLRK 2167
Query: 856 LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL----LQEEEE 911
E + RR+Q ++ + + + E + +H +A+ L+++ + EQ+L LQ EE
Sbjct: 2168 EAEQEAARRAQAEQAALRQKQAADAEME--KHKKFAEQTLRQKAQVEQELTTLRLQLEET 2225
Query: 912 ELQR---EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
+ Q+ +E +R + E R+ Q+++E + + E + + R + L+
Sbjct: 2226 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD 2285
Query: 969 KE--EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
K+ ++ L EE EK ++ E + + L EE ++R E+ ++K +
Sbjct: 2286 KDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQA 2345
Query: 1027 QQEEEQLLRE----EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK 1082
QE +L E +++K QE+ R+ +E++E Q +QL E + +R E ERQ +
Sbjct: 2346 VQEATRLKAEAELLQQQKELAQEQARRLQEDKE--QMAQQLAEETQGFQRTLEAERQ--R 2401
Query: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYRE 1142
+ E+ E E+L E R Q R EE+ Q+ +Q E EK R EL Q +
Sbjct: 2402 QLEMSAEAERLKLRVAEMSR-----AQARAEEDAQRFRKQ-AEEIGEKLHRTELATQEKV 2455
Query: 1143 EEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREE 1202
E ++ + +R R+ + RE+E+LQQE + L + +E + ++E+ +E
Sbjct: 2456 TLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQET 2515
Query: 1203 EELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQ 1262
+ LQ Q + E + S L+ + E+E A + + + +Q R E+ Q + +Q
Sbjct: 2516 QALQ-----QSFLSE-KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR--EEQQRQQQQ 2567
Query: 1263 SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR 1322
+Q+ Q L+ +E R Q E E+ R +Q+E ++ +++ +++++LL
Sbjct: 2568 MEQERQRLVASMEEARRRQH------------EAEEGVRRKQEELQQLEQQRRQQEELLA 2615
Query: 1323 EEREEKRRRQETDRKFREEEQLLQEREEQPLRRQE 1357
EE +++ RE+ QLL+E+ L E
Sbjct: 2616 EE----------NQRLREQLQLLEEQHRAALAHSE 2640
Score = 324 bits (830), Expect = 6e-88
Identities = 461/1845 (24%), Positives = 811/1845 (43%), Gaps = 259/1845 (14%)
Query: 253 LRKEEEK--LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQ 310
L+ EE++ L E Q L++ ++ L ER+ + Q L +
Sbjct: 944 LKPEEQRQALHSLELHYQAFLRDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQGA 1003
Query: 311 EEERREQQ--EERREQQERREQQEERREQQLR--------REQEERREQQLRREQEEERR 360
+EE R Q+ E ++ + + E E R +LR RE +R +Q + + E E
Sbjct: 1004 QEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGL 1063
Query: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
+ + R E E+ L + LR E +L L + +Q+R + E+
Sbjct: 1064 GKGVARLSAEA--EKVLALPEPSPAAPTLRSELELT----LGKLEQVRSLSAIYLEKLKT 1117
Query: 421 REQQLRREQEEERHEQKHEQERREQRLKR----EQEERRDWLKR---EEETERHEQERRK 473
+R Q E + HE++ +E + E E + LK+ + E ++ + +
Sbjct: 1118 ISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALR 1177
Query: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
+L+ QE R + E + E+ R QL + Q RQ E E+L ++LR
Sbjct: 1178 DELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLR 1237
Query: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE 593
+ E + L ++ R QE+ + + + R+QL R+E+ + ++R
Sbjct: 1238 YYR-------ESADPLGAWLQDARRRQEQIQAMPLADSQAVREQL--RQEQALLEEIERH 1288
Query: 594 QEERLE-QRLKREEVERLEQEERREQRLKRE-EP--EEERRQQLLKSEEQEERRQQQLRR 649
E+ E QR ++ + ++ E + K + EP ++ ++ E + LR
Sbjct: 1289 GEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRT 1348
Query: 650 EQQERR----------EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
E + L+R EEEERL ++ + E E E E A E+Q Q
Sbjct: 1349 HYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQL------ 1402
Query: 700 RIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQ- 758
+EA A+ R K+ QR QEE RR E+ + Q+++R+ +++
Sbjct: 1403 ----------AEAHAQAKAQAEREAKELQQRM---QEEVVRREEAAVDAQQQKRSIQEEL 1449
Query: 759 QEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQ-----REQRFLPE 813
Q+ Q + Q +A + R RL +R R QL A ERQ+ Q
Sbjct: 1450 QQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVR-LQLEATERQRGGAEGELQALRAR 1508
Query: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRR----ERAQQLQEEEDGLQEDQERRRSQEQR 869
EE E ++RQ +E + L+ ++E ++R E A +++ E + +E Q ++ E+
Sbjct: 1509 AEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEEL 1568
Query: 870 RDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQ 929
R Q EE +R R A E+ R+ Q L+ + + E + KR E+
Sbjct: 1569 R-----LQAEEAERRLRQ------AEVERARQVQVALETAQRSAEAELQSKRA-SFAEKT 1616
Query: 930 YREEEQLQQEEEQL--LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE 987
+ E LQ+E + LREE E+R +Q+ E + +++ ++ E L R R + E
Sbjct: 1617 AQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAE 1676
Query: 988 KKYREEEELQQEEEQLLRE-EREKRRRQEWERQYRKKDELQQEE------------EQLL 1034
+ +++ Q E E+ E ERE RRR + E Q ++ EL ++E +Q L
Sbjct: 1677 EVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRL 1736
Query: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERE--TRRRQELERQYRKEEELQQEEEQ 1092
E+E RL+ Q ++ +L +EE L E T++RQELE + K ++ E E
Sbjct: 1737 AAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK---VRAEMEV 1793
Query: 1093 LL----REEPEKRRRQERERQCREEE-----ELQQEEEQL--LREEREKRRR---QELER 1138
LL R E E R E+ +Q E E EL +E +L L EE +++R+ ++ R
Sbjct: 1794 LLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAAR 1853
Query: 1139 QYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE--QEKRRQERE 1196
Q E E V E+ + E R + E E +E+E + +L +E Q +R +E+
Sbjct: 1854 QRAEAERVLAEKLAAIGEAT--RLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQA 1911
Query: 1197 RQYREE-EELQRQKRK----QRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFR 1251
Q++ + EE Q RK + R + D Q +E + + K +
Sbjct: 1912 AQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAEL 1971
Query: 1252 QLEDSQLRDR-----QSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE 1306
+LE ++R +S++ + Q++ E+ERRR + +R ++ L EE E
Sbjct: 1972 ELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER---VQKSLAAEE--E 2026
Query: 1307 AKRRDRKSQEEKQLLREEREEKRR-RQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365
A R+ + + EE + L+ + EE RR R+ +++ + QL QE ++ L+ +E+ F +
Sbjct: 2027 AARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ 2086
Query: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425
+ + Q + L++EQ + Q R + E R E ++ R +R+ + +Q+
Sbjct: 2087 QKEQELQ--QTLQQEQSVLDQLRG----EAEAARRAAEEAEEARVQAEREAAQSRRQVEE 2140
Query: 1426 QERDRKFREEEQQVR--------------RQERERKFLEEEQQLRQ--------ERHRKF 1463
ER ++ EE+ Q R QE R+ E+ LRQ E+H+KF
Sbjct: 2141 AERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKF 2200
Query: 1464 REEEQLLQEREEQ-------QLHRQERDRKFLEEEQQLRRQE-----RDRKFREQELRSQ 1511
E+ + + EQ QL + + L+EE Q + E R R E+EL S
Sbjct: 2201 AEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSV 2260
Query: 1512 EPERKFLEEEQQLHRQQRQRKFLQEEQQLRR--QERGQQRRQDRDRKFR------EEEQL 1563
+ + L + + + + L+++ +R QE ++ +Q + R E +L
Sbjct: 2261 RVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARL 2320
Query: 1564 RQEREE---QQLSRQERDRKFR----------------LEEQKVRRQEQERKFMEDEQQL 1604
RQ EE QQ + E+ K + L++QK QEQ R+ ED++Q+
Sbjct: 2321 RQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQM 2380
Query: 1605 RRQEGQQQLRQERDRKFREDEQLLQEREEQQLH----RQERDRKFLEEEPQLRRQEREQ- 1659
+Q ++ +R + QL E ++L R + EE+ Q R++ E+
Sbjct: 2381 AQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI 2440
Query: 1660 -QLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQ---Q 1715
+ H + +E+ L+Q E ++RQ+ D + + ERE++ LQ+E Q
Sbjct: 2441 GEKLHRTELATQEKVTLVQTLE---IQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2497
Query: 1716 LRRQELERKFREEEQLRQET---------EQEQLRRQERYRKILEEEQLRPE---REEQQ 1763
L+ +E++ ++EQL QET E++ L ++ER+ +E+E+ + E ++E
Sbjct: 2498 LKSEEMQTV--QQEQLLQETQALQQSFLSEKDSLLQRERF---IEQEKAKLEQLFQDEVA 2552
Query: 1764 LRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE-EEQLRQEREE-QQLRPQQRDGKY 1821
+Q R+ + R+++Q+ QER+ +E+ R+ E EE +R+++EE QQL Q+R +
Sbjct: 2553 KAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEE 2612
Query: 1822 RWEEEQLQLEEQEQRL-RQERDRQYRAEEQFATQEKSRR-------------EEQELWQE 1867
EE +L EQ Q L Q R +EE A+Q + + E E
Sbjct: 2613 LLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHS 2672
Query: 1868 EEQKRRQERERKLREEHI---RRQQKEEQRHRQVGEIKSQEGKGH 1909
+ RR+ ++L+E I Q+ Q H V E+ +E H
Sbjct: 2673 FDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRH 2717
Score = 321 bits (822), Expect = 5e-87
Identities = 452/1778 (25%), Positives = 777/1778 (43%), Gaps = 303/1778 (17%)
Query: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ--LRREQQL-----------RR 421
Q LRR+ QL R L + L+ E+Q + L Q LR Q R
Sbjct: 924 QSLRRDVQLIRSWSLATFRTLKPEEQRQALHSLELHYQAFLRDSQDAGGFGPEDRLMAER 983
Query: 422 E------------QQLRREQEEERHEQKHEQERREQRLKREQEERRDW----LKREEETE 465
E Q L + +EE Q+ E ++ RL+ E E R L ++E
Sbjct: 984 EYGSCSHHYQQLLQSLEQGAQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPA 1043
Query: 466 RHEQERRKQQLKRDQEEE-----------RRERWLKLEEEERREQQERREQQLRREQ-EE 513
R +R +Q K E E E+ L L E R E +L + E+
Sbjct: 1044 RECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQ 1103
Query: 514 RREQRLKRQEEEERLQQRLR----SEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
R E+ + + +R +E+ LR +E+ +E LE + + R
Sbjct: 1104 VRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLR 1163
Query: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER 629
Q E + + R + R +E ERL+QR +VE ER Q L ER
Sbjct: 1164 AQAEAQQPTF--DALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLL-------ER 1214
Query: 630 RQQLLKSEEQEERRQQQLRREQQERRE---------QRLKREEEE---------ERLEQR 671
Q +L + +R +QL R+ + RE Q +R +E+ + + ++
Sbjct: 1215 WQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQ 1274
Query: 672 LKREH---EEERREQELAEEEQEQARERIKS------RIPKWQWQLESEADARQSKVYSR 722
L++E EE R E EE Q A++ I + ++ ++ QLE A + +
Sbjct: 1275 LRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK-----K 1329
Query: 723 PRKQEGQRRRQEQEEKRRRRESEL----------------QWQEEERAHRQQQEEEQRRD 766
P+ Q G ++ R SEL + +EEER QQ+ EE+ R
Sbjct: 1330 PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER- 1388
Query: 767 FTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQR-EQRFLPEEEEKEQRRRQRR 825
+ E E+ RQ A + Q ER+ A+E QQR ++ + EE ++Q+R
Sbjct: 1389 ---LAEVEAALEKQRQLAEAHAQAKAQAERE--AKELQQRMQEEVVRREEAAVDAQQQKR 1443
Query: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR 885
++ELQ L + + + + +A+Q + E + R R +E+ R R QLE ++R
Sbjct: 1444 SIQEELQQLRQSSEAEIQAKARQAEAAE------RSRLRIEEEIRVV--RLQLEATERQR 1495
Query: 886 ---RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQER------------QY 930
L A A E+ +++ QEE E L+R+ +++ +R+ Q
Sbjct: 1496 GGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAA 1555
Query: 931 REEEQLQQ--EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK 988
RE+++ Q EE +L EE E+R RQ + R+ + + ++ E + +R EK
Sbjct: 1556 REKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEK 1615
Query: 989 KYREEEELQQEEEQL--LREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
+ E LQ+E + LREE E+R +Q+ E + R ++E ++E E+ + E RL+ +
Sbjct: 1616 TAQLERSLQEEHVAVAQLREEAERRAQQQAEAE-RAREEAERELERWQLKANEALRLRLQ 1674
Query: 1047 ERQYREEEELQQEEEQLLGEE--RETRRRQELERQYRKEEELQQEE----EQLLREEPEK 1100
+ +++ L Q E + EE RE RRR + E Q ++ EL ++E QL ++
Sbjct: 1675 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1734
Query: 1101 RRRQERER-QCREEEELQQEEEQLLREEREK---------RRRQELERQYREEEEVQQEE 1150
R E+E + R E E +++ QLL EE + ++RQELE E +V+ E
Sbjct: 1735 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA---ELAKVRAEM 1791
Query: 1151 EQLL----REEPEKRRRQELERQYREEE-----ELQQEEEQLLREEQEKRRQERERQYRE 1201
E LL R E E R E +Q E E EL +E +L +E +RQ RQ E
Sbjct: 1792 EVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ---RQLAE 1848
Query: 1202 EEELQRQKRKQRYRDEDQRS-DLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQL-- 1258
E+ +++ +R E + + + E E A+++ K ENE+ R+L + +
Sbjct: 1849 EDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKE-----KEAENERLRRLAEDEAFQ 1903
Query: 1259 RDRQSQQDLQH-------LLGEQQERDREQERRRWQQRD----RHFPEEEQLEREEQKEA 1307
R R +Q QH L ++ D E ER++ D R EEE L + E
Sbjct: 1904 RRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEK 1963
Query: 1308 KR-----------RDRKSQEEKQLLREEREEKRRRQ-----ETDRKFREEEQLLQEREEQ 1351
R R + E+ +E+ E + RQ E +R+ RE E ER ++
Sbjct: 1964 AAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE----ERVQK 2019
Query: 1352 PLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR-------------QERERKFLKEEQQ 1398
L +E + R+ L E+ + +EE +RLR QE +K L+ E++
Sbjct: 2020 SLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEK 2079
Query: 1399 LRC---QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ-ERE----RKFLE 1450
Q++EQ+L+Q ++ +Q E R+ EE ++ R Q ERE R+ +E
Sbjct: 2080 AHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVE 2139
Query: 1451 EEQQLRQERHRKFREE-------EQLLQEREEQQLHRQERDRKFLEEEQQLRRQ-ERDRK 1502
E ++L+Q + + E+L +E E++ R + ++ L ++Q + E+ +K
Sbjct: 2140 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2199
Query: 1503 FREQELRSQ-EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561
F EQ LR + + E++ QL Q+ L EE Q + E + RQ R EEE
Sbjct: 2200 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQ---RSQVEEE 2256
Query: 1562 QLRQEREEQQLSRQERDRKFRLEEQK----VRRQEQERKFMEDEQQLRRQEGQQQLRQER 1617
+ ++LS+ K R+E + +R ++ ++F+++E + +Q ++ R
Sbjct: 2257 LFSVRVQMEELSKL----KARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSV 2312
Query: 1618 DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQ 1677
+ E +L Q EE ++ K L+E+ Q ++ + + E +LLQ
Sbjct: 2313 AAQ--EAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEAT----------RLKAEAELLQ 2360
Query: 1678 EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ 1737
+ +E QE+ R+ +E+++Q+ +Q L EE Q ++ LE + + + ++ E E+
Sbjct: 2361 QQKELA---QEQARRLQEDKEQMAQQ------LAEETQGFQRTLEAERQRQLEMSAEAER 2411
Query: 1738 EQLRRQERYRKILEEEQLRPEREEQQLRRQERD--RKFREEEQLRQER----EEQQLRSQ 1791
+LR E R Q R E + Q+ R+Q + K E QE+ + +++ Q
Sbjct: 2412 LKLRVAEMSRA-----QARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2466
Query: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYR----- 1846
+SD + E E ++ + QQ + + E++Q +QEQ L++ + Q
Sbjct: 2467 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2526
Query: 1847 ----AEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIK 1902
E+F QEK++ E+ L+Q+E K +Q RE + +RQQ++ ++ RQ
Sbjct: 2527 DSLLQRERFIEQEKAKLEQ--LFQDEVAKAQQLREEQ------QRQQQQMEQERQRLVAS 2578
Query: 1903 SQEGKGHGRLLEPGTHQFASVPVRSSPLYEYIQEQRSQ 1940
+E + E G + + L + Q++R Q
Sbjct: 2579 MEEARRRQHEAEEGVRR------KQEELQQLEQQRRQQ 2610
Score = 311 bits (798), Expect = 3e-84
Identities = 324/1270 (25%), Positives = 597/1270 (47%), Gaps = 197/1270 (15%)
Query: 98 EKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE- 156
+ +A+ + + LQ R QEE RR + ++ + +R Q+ +Q R+ +E E Q++
Sbjct: 1408 QAKAQAEREAKELQQRMQEEVVRR---EEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKA 1464
Query: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERR-AEEEQLQSCKGHETEEFPDEEQLRRREL 215
+Q +R R R +EE+ R + + E +R E +LQ+ + EE +++ + E
Sbjct: 1465 RQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRA-RAEEAEAQKRQAQEEA 1523
Query: 216 LELRRKGREEKQQQRR---ERQDRVFQEEEEKEWRKRETVLRKE--------EEKLQEEE 264
LRR+ ++E Q++R+ E RV E E ++R +E E +L++ E
Sbjct: 1524 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1583
Query: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
+R R++Q E ++ EL+ +R ++ +L R Q + RE+ E R +Q
Sbjct: 1584 VERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1643
Query: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
Q E+ E E++L R Q + E R Q EE +Q+ + E E+++++ RE + R
Sbjct: 1644 QAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR 1703
Query: 385 ---REQQLRR----EQQLRREQQLRR---EQQLRREQQLRR----------EQQLRREQQ 424
EQ +R+ EQ+L +++QL +Q+L EQ+L R ++QL E+
Sbjct: 1704 GKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEEL 1763
Query: 425 LRREQEEERHEQKHEQ-ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD---- 479
R ++E QK ++ E +++ E E R EE R E+ KQ+L+ +
Sbjct: 1764 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1823
Query: 480 -------------QEEERRERWLKLEEEERREQQERR-----------------EQQLRR 509
EE +R+R L E+ R+ + R E ++
Sbjct: 1824 RELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL 1883
Query: 510 EQEERREQRLKRQEEEERLQQRLRSEQ--QLRREQEERREQLLKR-----EEEKRLEQER 562
+++E +RL+R E+E Q+R EQ Q + + EER QL K E +K L ++
Sbjct: 1884 KEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDT 1943
Query: 563 REQRLKREQE---------------------------ERRDQLLKREEER---------- 585
QR + E+E D L +E+
Sbjct: 1944 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 2003
Query: 586 -RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
++R +RE EER+++ L EE E Q + + ++R + + E ++L + EQE RQ
Sbjct: 2004 AEEERRRREAEERVQKSLAAEE-EAARQRKAALEEVERLKAKVEEARRLRERAEQESARQ 2062
Query: 645 QQLRREQQERREQRLKR------EEEEERLEQRLKREH---EEERREQELAE---EEQEQ 692
QL +E ++R Q ++ +++E+ L+Q L++E ++ R E E A EE E+
Sbjct: 2063 LQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2122
Query: 693 ARERIKSRIPKWQWQLESEADARQS---KVYSRPRKQ---EGQRRRQEQEEKRRRRESEL 746
AR + + + + Q+E +QS + +R + Q E R+ EQE RR + +
Sbjct: 2123 ARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQA 2182
Query: 747 QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA-----RPPLREQRERQLRAE 801
++++ A + ++ ++ + T + +A+ + E RL + L ++ ++L+AE
Sbjct: 2183 ALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAE 2242
Query: 802 ERQQREQRFLPEEE--------EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
+ QR EEE E+ + + R E E L +++ QR LQEE
Sbjct: 2243 ATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR-----FLQEEA 2297
Query: 854 DGLQE--DQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEE 911
+ +++ ++ R S + + R EE+ ++R AL E++ KE+ +E
Sbjct: 2298 EKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQR-------ALAEKMLKEKMQAVQEAT 2350
Query: 912 ELQRE----EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967
L+ E +++K QEQ R+ +E++ +Q +QL E + +R E ERQ + + +
Sbjct: 2351 RLKAEAELLQQQKELAQEQARRLQEDK--EQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2408
Query: 968 QKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR----QEWERQYRKK 1023
+ +L E + + + E R ++ ++ E+L R E + + Q E Q ++
Sbjct: 2409 AERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQS 2468
Query: 1024 D-ELQQEEEQLLREEREKRRLQERER--QYREEEELQQEEEQLLGEERETRRR--QELER 1078
D + ++ E + EREK +LQ+ + Q + EE ++EQLL E + ++ E +
Sbjct: 2469 DHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDS 2528
Query: 1079 QYRKEEELQQEE---EQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135
++E ++QE+ EQL ++E K +Q RE Q R++++++QE ++L+ E RR
Sbjct: 2529 LLQRERFIEQEKAKLEQLFQDEVAK-AQQLREEQQRQQQQMEQERQRLVASMEEARR--- 2584
Query: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
RQ+ EE V++++E+L Q+LE+Q R++EEL EE Q LRE+ + ++
Sbjct: 2585 --RQHEAEEGVRRKQEEL----------QQLEQQRRQQEELLAEENQRLREQLQLLEEQH 2632
Query: 1196 ERQYREEEEL 1205
EE+
Sbjct: 2633 RAALAHSEEV 2642
Score = 212 bits (539), Expect = 3e-54
Identities = 221/808 (27%), Positives = 387/808 (47%), Gaps = 87/808 (10%)
Query: 88 ALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRR--QKRQEQE 145
A+G+AT L E KE+ + R+ + F+ R+LEE+ Q + ++R Q
Sbjct: 1868 AIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQ--RRRLEEQAAQHKADIEERLAQL 1925
Query: 146 RELAEGEEQSEKQERLEQRDRQRR--DEELWRQRQEWQEREERRAE-EEQLQSCKGHETE 202
R+ ++ E + +K +E RQRR +EE+ + +++ +AE E +L + +
Sbjct: 1926 RKASDSELERQK-GLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA-- 1982
Query: 203 EFPDEEQLRRRELLEL----RRKGREEKQQQRRERQDRVFQE--EEEKEWRKRETVLRKE 256
E+ LR +E EL +R+ E++++RRE ++RV + EE+ R+R+ L +
Sbjct: 1983 ----EDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV 2038
Query: 257 EE-KLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL---RREQQLRRKQEE 312
E K + EE +R RE E+E + QE ++R + E++ ++EQ+L++ ++
Sbjct: 2039 ERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQ 2098
Query: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER 372
E+ + R E + R EE E R Q ER Q RR+ EE R +Q EQ + R
Sbjct: 2099 EQSVLDQLRGEAEAARRAAEEAEE---ARVQAEREAAQSRRQVEEAERLKQSAEEQAQAR 2155
Query: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLR----------REQQLRREQQLRRE 422
+ Q E +LR+E + ++ + EQ R++Q EQ LR++ Q+ +E
Sbjct: 2156 AQAQAAAE-KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQE 2214
Query: 423 QQLRREQEEERHEQKHEQERREQRLKREQEE---RRDWLKREEETERHEQERRKQQLKRD 479
R Q EE QK+ + QRLK E E +R ++ E + R + E + R
Sbjct: 2215 LTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARI 2274
Query: 480 QEEER------RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
+ E R ++ + +EE + ++ E+ R + RL++ EE+ QQR
Sbjct: 2275 EAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2334
Query: 534 SEQQLRREQEERRE--------QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585
+E+ L+ + + +E +LL++++E EQ RR Q E +E+ Q L E +
Sbjct: 2335 AEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ----EDKEQMAQQLAEETQG 2390
Query: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ 645
Q+ L+ E++ +LE + E ++ E R Q E+ + R+Q E E+ +
Sbjct: 2391 FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQ---AEEIGEKLHRT 2447
Query: 646 QLRREQQERREQRLK-REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKW 704
+L +++ Q L+ + ++ + +RL+ E RE+E ++E + + + +
Sbjct: 2448 ELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQ 2507
Query: 705 QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR 764
Q QL E A Q S + R EQE+ + Q ++E A QQ EEQ+
Sbjct: 2508 QEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE-----QLFQDEVAKAQQLREEQQ 2562
Query: 765 RDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQR 824
R +++ E+ RQRL A + E R RQ AEE +R+Q EE +Q +QR
Sbjct: 2563 RQ-------QQQMEQERQRLVA--SMEEARRRQHEAEEGVRRKQ------EELQQLEQQR 2607
Query: 825 REREKELQFLEEEEQLQRRERAQQLQEE 852
R++E+ L EE + RE+ Q L+E+
Sbjct: 2608 RQQEE----LLAEENQRLREQLQLLEEQ 2631
Score = 151 bits (382), Expect = 5e-36
Identities = 162/632 (25%), Positives = 294/632 (46%), Gaps = 80/632 (12%)
Query: 99 KRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQ-----------ERE 147
+RA + +E+ +Q R+ RR Q+EE +R +Q +EQ E+
Sbjct: 2114 RRAAEEAEEARVQAEREAAQSRR------QVEE--AERLKQSAEEQAQARAQAQAAAEKL 2165
Query: 148 LAEGEEQSEKQERLEQ---RDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
E E+++ ++ + EQ R +Q D E+ + ++ ++ ++A+ EQ + + EE
Sbjct: 2166 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2225
Query: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQD----RVFQEEEEK-----EWRKRETVLRK 255
++ L EL L+ + E +Q+ + ++ RV EE K E R +LR
Sbjct: 2226 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRD 2285
Query: 256 EE--EKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ--EEEQQQQRLRREQQLRRK-- 309
++ ++ +EE ++ +++ EE +L + QE R RQ EE+ QQR E+ L+ K
Sbjct: 2286 KDNTQRFLQEEAEKMKQVAEEAARL-SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQ 2344
Query: 310 --QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE------EERRE 361
QE R + + E +QQ+ Q++ RR Q E +E+ QQL E + E R+
Sbjct: 2345 AVQEATRLKAEAELLQQQKELAQEQARRLQ----EDKEQMAQQLAEETQGFQRTLEAERQ 2400
Query: 362 QQLRREQEEER---REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
+QL E ER R ++ R Q E R +Q + +L ++++ Q
Sbjct: 2401 RQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT 2460
Query: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR 478
L ++Q E E E ER +++L Q+E + + EE + +QE+ Q+ +
Sbjct: 2461 LEIQRQQSDHDAERLREAIAELEREKEKL---QQEAKLLQLKSEEMQTVQQEQLLQETQA 2517
Query: 479 DQEEERRERWLKLEEEERREQQERREQQL-----RREQEERREQRLKRQEEEERLQQRLR 533
Q+ E+ L+ E EQ++ + +QL + Q+ R EQ+ ++Q+ E+ Q+ +
Sbjct: 2518 LQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVA 2577
Query: 534 SEQQLRREQEERREQLLKREEE-KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592
S ++ RR Q E E + +++EE ++LEQ+RR+Q ++LL E +R +++L+
Sbjct: 2578 SMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ----------EELLAEENQRLREQLQL 2627
Query: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRRE-- 650
+E+ EEV + + R+ + +E + E LRR+
Sbjct: 2628 LEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGP------AAEAEPEHSFDGLRRKVS 2681
Query: 651 QQERREQRLKREEEEERLEQRLKREHEEERRE 682
Q +E + EE +RL Q E RRE
Sbjct: 2682 AQRLQEAGILSAEELQRLAQGHTTVDELARRE 2713
Score = 96.3 bits (238), Expect = 3e-19
Identities = 86/335 (25%), Positives = 166/335 (49%), Gaps = 42/335 (12%)
Query: 80 KVAQACYYALGQATGLDEEKRARCDGKESLLQDRR------QEEDQRRFEPRDRQLEEEP 133
K+ Q A + E R R +E L Q R +E+ Q E + E E
Sbjct: 2299 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAEL 2358
Query: 134 GQRRRQKRQEQERELAEGEEQSEKQ--------ERLEQRDRQRRDE-----ELWRQRQEW 180
Q++++ QEQ R L E +EQ +Q +R + +RQR+ E E + R
Sbjct: 2359 LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAE 2418
Query: 181 QEREERRAEEEQLQSCKGHET-------EEFPDEEQLRRRELLELRRKGREEKQQQRRE- 232
R + RAEE+ + K E E +E++ + LE++R+ + ++ RE
Sbjct: 2419 MSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREA 2478
Query: 233 ------RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRK---LER 283
++++ QE + + + E ++E+ LQE + +Q L E++ L++ +E+
Sbjct: 2479 IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQ 2538
Query: 284 QELRRER--QEEEQQQQRLRREQQLRRKQEEERREQ----QEERREQQERREQQEERREQ 337
++ + E+ Q+E + Q+LR EQQ +++Q E+ R++ EE R +Q E+ R+++
Sbjct: 2539 EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQE 2598
Query: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEER 372
+L++ +++RR+Q+ +E +R +QL+ +E+ R
Sbjct: 2599 ELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHR 2633
Score = 37.4 bits (85), Expect = 0.14
Identities = 73/313 (23%), Positives = 122/313 (38%), Gaps = 57/313 (18%)
Query: 933 EEQLQQEEEQLLREEREKRRRQER----ERQYRKDKKLQQKEEQLL--GEEPEKRRRQER 986
E+QL+ E E+L +R + Q E Q + L Q + +LL G+ P++ ER
Sbjct: 408 EKQLRSEFERLECLQRIVTKLQMEAGLCEEQLNQADALLQSDVRLLAAGKVPQRAGEVER 467
Query: 987 E-KKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ-EEEQLLR--------- 1035
+ K L + Q L++ R + Q + R YR + L E LR
Sbjct: 468 DLDKADSMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPA 527
Query: 1036 EEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE----------LERQYRKEEE 1085
+ + LQ +R+ E+ + + LL E + R + +E Q
Sbjct: 528 TQVAQVTLQSVQRRPELEDSTLRYLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRG 587
Query: 1086 LQQEEEQLLREEPEKRRRQERE---------RQCREEEELQQEEEQLLREEREKRRRQEL 1136
L Q E+ R + E+ R E + R C +LQ + LL + + R E
Sbjct: 588 LHQSIEEF-RAKIERARSDEGQLSPATRGAYRDCLGRLDLQYAK--LLNSSKARLRSLES 644
Query: 1137 ERQY-------------REEEEV-----QQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178
+ +EEEEV + ++E +ELE + ++ +ELQ
Sbjct: 645 LHSFVAAATKELMWLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQN 704
Query: 1179 EEEQLLREEQEKR 1191
++LLRE+ R
Sbjct: 705 AGDRLLREDHPAR 717
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 335 bits (858), Expect = 3e-91
Identities = 218/752 (28%), Positives = 448/752 (59%), Gaps = 77/752 (10%)
Query: 865 SQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE-------EEEELQREE 917
S ++ ++ +L +ER LY E+L+K+ LQE E+ E+Q
Sbjct: 189 STRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNV 248
Query: 918 REKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEE 977
+E +R+ E+ + + Q +E++ R+E E R E+E++ RK ++ ++E+ L E+
Sbjct: 249 KELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR---EQEKKIRKQEEKMWRQEERLREQ 305
Query: 978 PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE 1037
K R QE EK +R+E+ L+++E++L +E+E R ++E R+++E QE+E+ + E+
Sbjct: 306 EGKMREQE-EKMWRQEKRLREQEKELREQEKELREQKE----LREQEEQMQEQEEKMWEQ 360
Query: 1038 REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE 1097
EK R QE E+ +R+EE L ++E+Q+ E+E + R + ER + ++E L+++EE++ +E
Sbjct: 361 EEKMREQE-EKMWRQEERLWEQEKQM--REQEQKMRDQEERMWEQDERLREKEERMREQE 417
Query: 1098 P---------EKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148
E+++ QE+E++ R++EE QEEE++ EREK+ R+E E +EE++Q+
Sbjct: 418 KMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERI--REREKKMREEEETMREQEEKMQK 475
Query: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208
+EE + +E ++ ++Q L Q +E+L ++E+ +EQE++ E+E + R++EE+ Q
Sbjct: 476 QEENMWEQEEKEWQQQRLPEQ---KEKLWEQEKM---QEQEEKIWEQEEKIRDQEEMWGQ 529
Query: 1209 KRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQ 1268
++K +R E R WE E+ K R+ EQ ++ D + R + Q+ +
Sbjct: 530 EKKM-WRQEKMREQEDQMWEQEE-----------KMRDQEQ--KMWDQEERMEKKTQEQE 575
Query: 1269 HLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEK 1328
+Q+E+ RE+ER R +R++ EEE++ RE++++ + ++ K QE+++ + E+ E
Sbjct: 576 KKTWDQEEKMREEERMR--EREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEE-- 631
Query: 1329 RRRQETDRKFREEEQLLQEREEQPLRRQ----ERDRKFREEELRHQEQGRKFLEEEQRLR 1384
+ QE + K E+E+ + E+EE+ +Q ++++ + E+++ QE K E+E+++
Sbjct: 632 -KMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQE---KMQEQEEKIW 687
Query: 1385 RQER-ERKFLKEEQQLRCQE--REQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRR 1441
QE+ E+K ++E++ QE RE++ ++R++K REEE+ + +E++ K +E+E++++
Sbjct: 688 EQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMM--REQEEKMQEQEEKMQE 745
Query: 1442 QERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLH-RQERDRKFLEEEQQLRRQERD 1500
QE E + E+++ E+ K E+++L +++E+ H + + K E+E+++R QE
Sbjct: 746 QEEE---MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEK 802
Query: 1501 RKFREQELRSQEPERKFLEE----EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRK 1556
+ +E+++R QE + + EE +++ Q ++ + QEE+ ++E+ +++ Q ++ K
Sbjct: 803 MRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEK 862
Query: 1557 FREEEQLRQEREEQQLSRQERDRKFRLEEQKV 1588
RE+E+ + +EE+ +E++ K R +E+K+
Sbjct: 863 MREQEEKMRGQEEKM---REQEEKMRGQEEKI 891
Score = 320 bits (819), Expect = 1e-86
Identities = 225/764 (29%), Positives = 438/764 (57%), Gaps = 87/764 (11%)
Query: 912 ELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE------EREKRRRQERERQYRKDKK 965
ELQR R ++ +Y EE L +E + L E E+ +++ E Q +
Sbjct: 180 ELQRALSAVSTRHKKADRYIEE--LTKERDALSLELYRNTITNEELKKKNAELQEKLPLA 237
Query: 966 LQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDE 1025
+K E L + E +R+ ER K + + +E++ R+E E R E E++ RK++E
Sbjct: 238 ESEKSEIQLNVK-ELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR---EQEKKIRKQEE 293
Query: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
+E+ LRE+ K R QE E+ +R+E+ L+++E++L +E+E R ++EL R++EE
Sbjct: 294 KMWRQEERLREQEGKMREQE-EKMWRQEKRLREQEKELREQEKELREQKEL----REQEE 348
Query: 1086 LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEE 1145
QE+E+ + E+ EK R QE E+ R+EE L ++E+Q+ RE+ +K R QE ER + ++E
Sbjct: 349 QMQEQEEKMWEQEEKMREQE-EKMWRQEERLWEQEKQM-REQEQKMRDQE-ERMWEQDER 405
Query: 1146 VQQEEEQLLREEP---------EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERE 1196
++++EE++ +E E+++ QE E++ R++EE QEEE++ +ERE
Sbjct: 406 LREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERI---------RERE 456
Query: 1197 RQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDS 1256
++ REEEE R++ ++ + E+ WE E+ +E +Q R E
Sbjct: 457 KKMREEEETMREQEEKMQKQEEN------MWEQEE-------------KEWQQQRLPEQK 497
Query: 1257 Q-LRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQ 1315
+ L +++ Q+ + + EQ+E+ R+QE W Q + + +E+ E+E+Q + + Q
Sbjct: 498 EKLWEQEKMQEQEEKIWEQEEKIRDQEEM-WGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 556
Query: 1316 EEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRK 1375
E+K +EER EK + QE ++K ++E+ ++E E R +ER++K REEE +EQ K
Sbjct: 557 EQKMWDQEERMEK-KTQEQEKKTWDQEEKMREEE----RMREREKKMREEEEMMREQEEK 611
Query: 1376 FLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQ---ERDRKF 1432
E+E+++ QE+E K ++E+++ QE+E+++ + ++ + +EE+ +Q E+ K
Sbjct: 612 MQEQEEKM--QEQEEKMWEQEEKM--QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667
Query: 1433 REEE---QQVRRQERERKFLEEE--QQLRQERHRKFREEEQLLQEREEQQLHRQERDRKF 1487
E E +Q + QE+E K E+E ++ QE+ +K ++E++ +E ++ ++ R+ +
Sbjct: 668 WEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE 727
Query: 1488 LEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQR---QRKFLQEEQQLRRQE 1544
+ EQ+ + QE++ K +EQE E E K E+E+++ QQR Q++ L E ++++ QE
Sbjct: 728 MMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQE 787
Query: 1545 R---GQQRRQDRDRKFREEEQLRQEREEQQLSRQER----DRKFRLEEQKVRRQEQERKF 1597
+ +++ +D++ K R +E+ + +EE+ ++E+ + K +E+K+ QE E+ +
Sbjct: 788 KIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQE-EKMW 846
Query: 1598 MEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQER 1641
++E+ + +GQ++ +E++ K R E+ ++E+EE+ ++E+
Sbjct: 847 GQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 318 bits (814), Expect = 4e-86
Identities = 234/776 (30%), Positives = 436/776 (56%), Gaps = 74/776 (9%)
Query: 199 HETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEE 258
H + F E Q R + R K + ++ + +D + E E L+K+
Sbjct: 172 HHSWHFAGELQ-RALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEE--LKKKNA 228
Query: 259 KLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318
+LQE+ P + E E + +++L+R+ L R + Q Q +E+ R QEEE REQ+
Sbjct: 229 ELQEKLPLAESEKSEIQLNVKELKRK-LERAKFLLPQVQTNTLQEEMWR--QEEELREQE 285
Query: 319 EERREQQERREQQEER-REQQLR-REQEER--REQQLRREQEEERREQQLRREQEEERRE 374
++ R+Q+E+ +QEER REQ+ + REQEE+ R+++ REQE+E REQ+ +++E RE
Sbjct: 286 KKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELRE 345
Query: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL-RREQQLRREQQLRREQEEER 433
Q+ EQ +E+++ +++ REQ+ E+ R+E++L +E+Q+R ++Q R+QEE
Sbjct: 346 QE---EQMQEQEEKMWEQEEKMREQE---EKMWRQEERLWEQEKQMREQEQKMRDQEERM 399
Query: 434 HEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEE 493
EQ +E+R++ +++ K EE + EQE++ RDQEE K++E
Sbjct: 400 WEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKT----RDQEE-------KMQE 448
Query: 494 EER---REQQERREQQLRREQEE---RREQRLKRQEEEERLQQRLRSEQQLRREQEERRE 547
EER RE++ R E++ REQEE ++E+ + QEE+E QQRL +++ EQE+ +E
Sbjct: 449 EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQE 508
Query: 548 QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERL---EQRLKR 604
Q EEK EQE + R+QEE Q E++ +Q REQE+++ E++++
Sbjct: 509 Q-----EEKIWEQEEK----IRDQEEMWGQ----EKKMWRQEKMREQEDQMWEQEEKMRD 555
Query: 605 EEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEE 664
+E + +QEER E++ + +E + +++ ++ EE+ R++++R E++ REQ K +E+
Sbjct: 556 QEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ 615
Query: 665 EERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPR 724
EE+++++ ++ E+E + QE E+ EQ + + W+ Q E ++ K++ +
Sbjct: 616 EEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPE---QKEKLWEHEK 672
Query: 725 KQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRL 784
QE Q + QEQEEK W++E+ + Q++E++ D + E ER ++
Sbjct: 673 MQE-QEKMQEQEEK--------IWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMR 723
Query: 785 SARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRE 844
+REQ E+ EE+ Q ++ + E+EEK + ++ ++ L E++E+L E
Sbjct: 724 EEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLP--EQKEKLWEHE 781
Query: 845 RAQQLQEEEDGLQEDQERRRSQEQR---RDQKWRWQLEEERKRRRHTLYAKPALQEQLRK 901
+ Q E++ + E +E+ R QE++ +++K R Q EE+ + + ++ + ++ +
Sbjct: 782 KMQ----EQEKIWEQEEKMRDQEEKMRGQEEKMRGQ-EEKMRGQEEKMWGQE--EKMWGQ 834
Query: 902 EQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERE 957
E+++ +EE+ +EE+ + + Q QE + RE+E+ + +E+ +RE+ EK R QE +
Sbjct: 835 EEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 318 bits (814), Expect = 4e-86
Identities = 201/702 (28%), Positives = 439/702 (62%), Gaps = 63/702 (8%)
Query: 775 EKSERGRQRLSARPPLREQR--ERQLRAEERQQREQR---FLPEEE----EKEQRRRQRR 825
E+ ++ L + PL E E QL +E +++ +R LP+ + ++E R++
Sbjct: 221 EELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 280
Query: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR 885
RE+E + ++EE++ R+E ++L+E+E ++E +E+ QE+R ++ + E+E++ R
Sbjct: 281 LREQEKKIRKQEEKMWRQE--ERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELR 338
Query: 886 RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLR 945
Q++LR++++ +QE+EE++ E+E++ R+++E+ +R+EE+L ++E+Q+
Sbjct: 339 E---------QKELREQEEQMQEQEEKMW--EQEEKMREQEEKMWRQEERLWEQEKQM-- 385
Query: 946 EEREKRRRQERERQYRKDKKLQQKEEQLLGEEP---------EKRRRQEREKKYREEEEL 996
E+E++ R + ER + +D++L++KEE++ +E E+++ QE+EKK R++EE
Sbjct: 386 REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445
Query: 997 QQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREK----RRLQERERQYRE 1052
QEEE++ EREK+ R+E E R+++E Q++E+ + E+ EK +RL E++ + E
Sbjct: 446 MQEEERI--REREKKMREE-EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 502
Query: 1053 EEELQQEEEQLLGEERETRRRQEL---ERQYRKEEELQQEEEQLLREEPEKRRRQER--- 1106
+E++Q++EE++ +E + R ++E+ E++ ++E+++++E+Q+ +E EK R QE+
Sbjct: 503 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE-EKMRDQEQKMW 561
Query: 1107 ERQCREEEELQQEEEQLLREE---REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRR 1163
+++ R E++ Q++E++ +E RE+ R +E E++ REEEE+ +E+E+ ++E+ EK +
Sbjct: 562 DQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQE 621
Query: 1164 QELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDL 1223
QE E+ + +EE++Q++EE++ EQE++ E+E + E++ L QK K + E +
Sbjct: 622 QE-EKMWEQEEKMQEQEEKMW--EQEEKMWEQEEKMWEQQRLPEQKEK-LWEHEKMQEQE 677
Query: 1224 KWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQER 1283
K Q E+E + + + K + ++ + + ++R+ +S ++ + + E++E REQE
Sbjct: 678 KMQ---EQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEE 734
Query: 1284 RRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQ 1343
+ +Q ++ +EE++ +E+K ++ ++ ++++ ++E+ + + + K E+E+
Sbjct: 735 KMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEE 794
Query: 1344 LLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQE 1403
++++EE+ +R QE + +EE++R QE+ K +E+++ QE E+ + +EE+ +E
Sbjct: 795 KMRDQEEK-MRGQEEKMRGQEEKMRGQEE--KMWGQEEKMWGQE-EKMWGQEEKMWGQEE 850
Query: 1404 REQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERE 1445
+ ++ Q ++ K RE+E+++ QE K RE+E+++R QE +
Sbjct: 851 KMEEKMQGQEEKMREQEEKMRGQE--EKMREQEEKMRGQEEK 890
Score = 317 bits (812), Expect = 7e-86
Identities = 197/743 (26%), Positives = 439/743 (59%), Gaps = 54/743 (7%)
Query: 528 LQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR---EQRLKREQEERRDQLLKREEE 584
LQ+ L + ++ + E+L K + LE R + LK++ E +++L E E
Sbjct: 181 LQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESE 240
Query: 585 RRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
+ + +L ++ +R +R K + +++ +E+ ++EE E+ +++ K EE+ R++
Sbjct: 241 KSEIQLNVKELKRKLERAKFL-LPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQE 299
Query: 645 QQLRREQQERREQRLKREEEEERLEQRLK--REHEEERREQELAEEEQEQARERIKSRIP 702
++LR ++ + REQ K +E+RL ++ K RE E+E REQ+ E++EQ +E+ +
Sbjct: 300 ERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEK--- 356
Query: 703 KWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEE 762
W+ E + ++ K++ + + Q ++ ++E++ R + E W+++ER +++EE
Sbjct: 357 --MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL---REKEE 411
Query: 763 QRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRR 822
+ R+ W+ EK ++ R+Q E+ ++ EER + ++ + EEEE + +
Sbjct: 412 RMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK-MQEEERIREREKKMREEEETMREQE 470
Query: 823 QRREREKELQFLEEEEQLQRRERAQQLQE--EEDGLQEDQERRRSQEQR-RDQKWRWQLE 879
++ ++++E + +EE++ Q++ +Q ++ E++ +QE +E+ QE++ RDQ+ W E
Sbjct: 471 EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE 530
Query: 880 EERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQE 939
++ R+ + + EQ E+++ +E++ +EER +++ QEQE++ ++E+ +E
Sbjct: 531 KKMWRQEKMREQEDQMWEQ---EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMRE 587
Query: 940 EEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGE-----EPEKRRRQEREKKYREEE 994
EE++ EREK+ R+E E +++K+Q++EE++ + E E++ +++ EK + +EE
Sbjct: 588 EERM--REREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEE 645
Query: 995 ELQQEEEQLLREEREKRRRQE-WERQ-YRKKDELQQEEEQLLREEREKRRLQERERQYRE 1052
++ ++EE++ ++R ++++ WE + ++++++Q++EE++ +E+ +++ QE+E++ +
Sbjct: 646 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWD 705
Query: 1053 EEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE 1112
+E++++EE +E E++ R+EEE+ +E+E+ ++E+ EK + QE E +E
Sbjct: 706 QEKMREEESM-----------REREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQE 754
Query: 1113 EEELQQE----EEQLLREEREK----RRRQELERQYREEEEVQQEEEQLLREEPEKRRRQ 1164
E+ +QE E+Q L E++EK + QE E+ + +EE+++ +EE+ +R + EK R Q
Sbjct: 755 EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEK-MRGQEEKMRGQ 813
Query: 1165 ELERQYREEEELQQEEEQLLREEQEKRRQERE---RQYREEEELQRQKRKQRYRDEDQRS 1221
E E+ +EE++ +EE++ +E++ QE + ++ + EE++Q Q+ K R ++E R
Sbjct: 814 E-EKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRG 872
Query: 1222 DLKWQWEPEKENAVRDNKVYCKG 1244
+ E E++ ++ K+YC G
Sbjct: 873 QEEKMREQEEKMRGQEEKIYCVG 895
Score = 311 bits (798), Expect = 3e-84
Identities = 221/772 (28%), Positives = 453/772 (58%), Gaps = 102/772 (13%)
Query: 460 REEETERHEQERRKQ------QLKRDQ--EEERRERWLKLEEEERREQQERREQQLRREQ 511
R ++ +R+ +E K+ +L R+ EE +++ +L+E+ + E+ E QL ++
Sbjct: 191 RHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKE 250
Query: 512 EERREQRLK---RQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLK 568
+R+ +R K Q + LQ+ + +++ REQE++ ++++EEK R+E+RL+
Sbjct: 251 LKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKK----IRKQEEKMW---RQEERLR 303
Query: 569 REQEERRDQLLKREEERRQQRLKREQEERLEQRLK--REEVERLEQEER-REQRLKREEP 625
++ + R+Q E+ RQ++ REQE+ L ++ K RE+ E EQEE+ +EQ K E
Sbjct: 304 EQEGKMREQ---EEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQ 360
Query: 626 EEERRQQLLKSEEQEER---RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERRE 682
EE+ R+Q K QEER +++Q+R ++Q+ R+Q + E++ERL RE EE RE
Sbjct: 361 EEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL-----REKEERMRE 415
Query: 683 QELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRR 742
QE E+ E+ RE + K+ + +K Q + ++EE+ R R
Sbjct: 416 QEKMWEQVEKMRE--------------------EKKMQEQEKKTRDQEEKMQEEERIRER 455
Query: 743 ESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEE 802
E +++ EEE R+Q+E+ Q+++ W+ EEK + ++ + L EQ + Q + E+
Sbjct: 456 EKKMR--EEEETMREQEEKMQKQEEN-MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 512
Query: 803 RQQREQRFLPEEE---EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQED 859
++E++ +EE ++++ RQ + RE+E Q E+EE++ R++ Q++ ++E+ +++
Sbjct: 513 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM--RDQEQKMWDQEERMEKK 570
Query: 860 QERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREE-- 917
+ + + +++K R EEER R R + +E +R++++ +QE+EE++Q +E
Sbjct: 571 TQEQEKKTWDQEEKMR---EEERMREREKKMREE--EEMMREQEEKMQEQEEKMQEQEEK 625
Query: 918 ---REKRRRQEQERQYREEEQLQQEEEQL-----LREEREKRRRQERERQYRKDKKLQQK 969
+E++ ++++E+ + +EE++ ++EE++ L E++EK E+ ++ +K+Q++
Sbjct: 626 MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK---MQEQEKMQEQ 682
Query: 970 EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE 1029
EE++ +E +++ QE+EKK ++E++++EE EREK+ R+E +E+ +E
Sbjct: 683 EEKIWEQEKMEKKTQEQEKKTWDQEKMREEESM---REREKKMREE--------EEMMRE 731
Query: 1030 EEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQEL-ERQYRKEEELQQ 1088
+E+ ++E+ EK + QE E + +EE++ ++EE++ ++R ++++L E + +E+E
Sbjct: 732 QEEKMQEQEEKMQEQE-EEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIW 790
Query: 1089 EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148
E+E+ +R++ EK R QE E+ +EE+++ +EE++ +E E+ + +EE++
Sbjct: 791 EQEEKMRDQEEKMRGQE-EKMRGQEEKMRGQEEKMWGQE---------EKMWGQEEKMWG 840
Query: 1149 EEEQLL-REEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQY 1199
+EE++ +EE + + Q E + RE+EE + +E+ +RE++EK R + E+ Y
Sbjct: 841 QEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIY 892
Score = 310 bits (794), Expect = 9e-84
Identities = 209/724 (28%), Positives = 429/724 (59%), Gaps = 51/724 (7%)
Query: 121 RFEPRDRQLEEEPGQRRRQKRQEQERELAEGE---EQSEKQERLEQRDRQRRDEELWRQR 177
R + DR +EE +R + + E + +E QE+L + ++ + +L +
Sbjct: 191 RHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQL-NVK 249
Query: 178 QEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRV 237
+ ++ E + Q+Q+ E E + EE+LR +E +++ + +Q++R Q+
Sbjct: 250 ELKRKLERAKFLLPQVQTNTLQE-EMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGK 308
Query: 238 FQEEEEKEWRKRETVLRKEEEKLQEEEPQ--RQRELQEEEEQLRKLERQELRRERQEEEQ 295
+E+EEK WR+ E LR++E++L+E+E + Q+EL+E+EEQ+++ E + +E + EQ
Sbjct: 309 MREQEEKMWRQ-EKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQ 367
Query: 296 QQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQ 355
+++ R+E++L +QE++ REQ+++ R+Q+ER +Q+ER LR ++E REQ+ EQ
Sbjct: 368 EEKMWRQEERL-WEQEKQMREQEQKMRDQEERMWEQDER----LREKEERMREQEKMWEQ 422
Query: 356 EEERREQQLRREQEEERREQQ--LRREQQLR-REQQLRREQQLRREQQLRREQQLRREQQ 412
E+ RE++ +EQE++ R+Q+ ++ E+++R RE+++R E++ REQ E++++++++
Sbjct: 423 VEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQ----EEKMQKQEE 478
Query: 413 LRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR 472
EQ+ + QQ R +++E+ ++ + + +E+++ ++E+ RD +EE E++
Sbjct: 479 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD----QEEMWGQEKKMW 534
Query: 473 KQQLKRDQEEERRERWLKLEEEERRE-QQERREQQLRREQEERREQRLKRQEEEERLQQR 531
+Q+ R+QE++ E+ K+ ++E++ QE R ++ +EQE++ + ++ EEER+++R
Sbjct: 535 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRER 594
Query: 532 ---LRSEQQLRREQEER---REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585
+R E+++ REQEE+ +E+ ++ +EEK EQE + Q + + E+ +++ ++EE+
Sbjct: 595 EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM 654
Query: 586 RQQRLKREQEERLEQRLKREEVERLEQEERR---EQRLKREEPEEERR---QQLLKSEEQ 639
+Q+ EQ+E+L + K +E E+++++E + +++++++ E+E++ Q+ ++ EE
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEES 714
Query: 640 EERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
R++++R E++ REQ K +E+EE+++ E EEE EQE EQE+ +
Sbjct: 715 MREREKKMREEEEMMREQEEKMQEQEEKMQ-----EQEEEMWEQEEKMWEQEEKMWE-QQ 768
Query: 700 RIPKWQWQL-ESEADARQSKVYSRPRKQEGQRRRQE-QEEKRRRRESELQWQEEERAHRQ 757
R+P+ + +L E E Q K++ + K Q + QEEK R +E +++ QEE+ ++
Sbjct: 769 RLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQE 828
Query: 758 Q----QEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE 813
+ QEE+ W EEK E Q +REQ E+ EE+ + ++ +
Sbjct: 829 EKMWGQEEKMWGQEEKMWGQEEKMEEKMQ--GQEEKMREQEEKMRGQEEKMREQEEKMRG 886
Query: 814 EEEK 817
+EEK
Sbjct: 887 QEEK 890
Score = 310 bits (794), Expect = 9e-84
Identities = 229/777 (29%), Positives = 435/777 (55%), Gaps = 112/777 (14%)
Query: 263 EEPQRQRELQEEEEQLRKLERQELRR---ERQEEEQQQQRLRREQQLRRKQEEERREQQE 319
EE ++R+ E + +EL++ E QE+ + + E QL K+ + + E+ +
Sbjct: 200 EELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAK 259
Query: 320 ERREQQERREQQEERREQQLRREQEERREQQ--LRREQEEERREQQLRREQEEERREQQL 377
Q + QEE + R++EE REQ+ +R+++E+ R+++ REQE + REQ+
Sbjct: 260 FLLPQVQTNTLQEE-----MWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQE- 313
Query: 378 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR-REQQLRREQQLRREQEEERHEQ 436
E+ R+E++LR +++ REQ E++LR +++LR +E+Q++ +++ EQEE+ EQ
Sbjct: 314 --EKMWRQEKRLREQEKELREQ----EKELREQKELREQEEQMQEQEEKMWEQEEKMREQ 367
Query: 437 KHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEER 496
+ + R+E+RL ++++ R+ +E+ R ++ER +Q +R +E+E R R E+E+
Sbjct: 368 EEKMWRQEERLWEQEKQMRE----QEQKMRDQEERMWEQDERLREKEERMR----EQEKM 419
Query: 497 REQQER-REQQLRREQEERREQRLKRQEEEERLQQR---LRSEQQLRREQEERREQLLKR 552
EQ E+ RE++ +EQE++ + ++ +EEER+++R +R E++ REQEE+ +++
Sbjct: 420 WEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEK----MQK 475
Query: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERL--EQRLKREEVERL 610
+EE EQE +E + +R E++ ++L ++E+ + Q+ EQEE++ ++ + +E +
Sbjct: 476 QEENMWEQEEKEWQQQRLPEQK-EKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMW 534
Query: 611 EQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQ 670
QE+ REQ + E EE+ R Q K +QEER +++ + ++++ +Q K EEE
Sbjct: 535 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERM--- 591
Query: 671 RLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQR 730
RE E++ RE+E EQE+ + QE +
Sbjct: 592 ---REREKKMREEEEMMREQEE-------------------------------KMQEQEE 617
Query: 731 RRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPL 790
+ QEQEEK W++EE+ Q+QEE+ W+ EEK +++ + L
Sbjct: 618 KMQEQEEK--------MWEQEEK--MQEQEEK-------MWEQEEKMWEQEEKMWEQQRL 660
Query: 791 REQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE---EQLQRRERAQ 847
EQ+E+ E+ Q++E+ EE+ EQ + +++ +E+E + ++E E+ RER +
Sbjct: 661 PEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREK 720
Query: 848 QLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQ 907
+++EEE+ ++E +E+ + QE++ ++ E+E K QE+ EQQ L
Sbjct: 721 KMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWE---------QEEKMWEQQRLP 771
Query: 908 EEEEELQREER--EKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE------RERQ 959
E++E+L E+ E+ + EQE + R++E+ + +E+ +R + EK R QE E+
Sbjct: 772 EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM 831
Query: 960 YRKDKKLQQKEEQLLG-EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQE 1015
+ +++K+ +EE++ G EE + + Q +E+K RE+EE + +E+ +RE+ EK R QE
Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQE 888
Score = 307 bits (787), Expect = 6e-83
Identities = 217/758 (28%), Positives = 445/758 (58%), Gaps = 89/758 (11%)
Query: 775 EKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKE-----QRRRQRREREK 829
E+ + R LS +L+ + + +E+ L E E+ E + +++ ER K
Sbjct: 200 EELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAK 259
Query: 830 ----ELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQR-RDQKWRWQLEEERKR 884
++Q +E++ R+E ++L+E+E +++ +E+ QE+R R+Q+ + + +EE+
Sbjct: 260 FLLPQVQTNTLQEEMWRQE--EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMW 317
Query: 885 RRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLL 944
R+ +++LR++++ L+E+E+EL RE++ +EQE Q +E+E+ E+E+ +
Sbjct: 318 RQ---------EKRLREQEKELREQEKEL----REQKELREQEEQMQEQEEKMWEQEEKM 364
Query: 945 REEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQL- 1003
RE+ EK RQE ER + ++K+++++E+++ +E R E++++ RE+EE +E+E++
Sbjct: 365 REQEEKMWRQE-ERLWEQEKQMREQEQKMRDQE---ERMWEQDERLREKEERMREQEKMW 420
Query: 1004 --LREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEE 1061
+ + RE+++ QE E++ R ++E QEEE++ EREK+ +E E +EE++Q++EE
Sbjct: 421 EQVEKMREEKKMQEQEKKTRDQEEKMQEEERI--REREKKMREEEETMREQEEKMQKQEE 478
Query: 1062 QLLGEERETRRRQELERQYRK--EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE 1119
+ +E + ++Q L Q K E+E QE+E+ + E+ EK R++EE+ +
Sbjct: 479 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK---------IRDQEEMWGQ 529
Query: 1120 EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE 1179
E+++ R+E K R QE + +EE+ QE++ +EE +++ QE E++ ++EE +E
Sbjct: 530 EKKMWRQE--KMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMRE 587
Query: 1180 EEQLLREEQEKRRQERERQYREEEE-LQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDN 1238
EE++ E+EK+ +E E RE+EE +Q Q+ K + ++E WE E++ ++
Sbjct: 588 EERM--REREKKMREEEEMMREQEEKMQEQEEKMQEQEEK-------MWEQEEKMQEQEE 638
Query: 1239 KVYCKGREN-EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEE 1297
K++ + + EQ ++ + Q Q ++ +H ++QE+ +EQE + W E+E
Sbjct: 639 KMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIW--------EQE 690
Query: 1298 QLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQE 1357
++E++ Q+ QE+K +E+ E+ +E ++K REEE++++E+EE + QE
Sbjct: 691 KMEKKTQE---------QEKKTWDQEKMREEESMREREKKMREEEEMMREQEE---KMQE 738
Query: 1358 RDRKFREEELRHQEQGRKFLEEEQRLRRQER---ERKFLKEEQQLRCQEREQQLRQDRDR 1414
++ K +E+E EQ K E+E+++ Q+R +++ L E +++ +EQ+ +++
Sbjct: 739 QEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM----QEQEKIWEQEE 794
Query: 1415 KFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQERE 1474
K R++E+++ QE K R +E+++R QE E+ + +EE+ QE + + +EE++ + E
Sbjct: 795 KMRDQEEKMRGQE--EKMRGQEEKMRGQE-EKMWGQEEKMWGQE-EKMWGQEEKMWGQEE 850
Query: 1475 EQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQE 1512
+ + Q ++ K E+E+++R QE + +E+++R QE
Sbjct: 851 KMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQE 888
Score = 306 bits (784), Expect = 1e-82
Identities = 210/755 (27%), Positives = 443/755 (58%), Gaps = 86/755 (11%)
Query: 648 RREQQERREQRLKREEEEERLE--------QRLKREHEEERREQELAEEEQEQARERIKS 699
R ++ +R + L +E + LE + LK+++ E + + LAE E+ + + +K
Sbjct: 191 RHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKE 250
Query: 700 RIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQE--QEEKRRRRESELQWQEEERAHRQ 757
K + A +V + ++E R+ +E ++EK+ R++ E W++EER +
Sbjct: 251 LKRKLE-----RAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERL--R 303
Query: 758 QQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEK 817
+QE + R W+ E++ LREQ E++LR +E++ REQ+ L E+EE+
Sbjct: 304 EQEGKMREQEEKMWRQEKR-------------LREQ-EKELREQEKELREQKELREQEEQ 349
Query: 818 EQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRR-DQKWRW 876
Q + ++ ++E + E+EE++ R+E ++L E+E ++E +++ R QE+R +Q R
Sbjct: 350 MQEQEEKMWEQEE-KMREQEEKMWRQE--ERLWEQEKQMREQEQKMRDQEERMWEQDERL 406
Query: 877 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQL 936
+ +EER R + ++ + E++R+E+++ +E+E+ R++ EK QE+ER RE E+
Sbjct: 407 REKEERMREQEKMWEQV---EKMREEKKM--QEQEKKTRDQEEKM--QEEER-IREREKK 458
Query: 937 QQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQER-----EKKYR 991
+EEE+ +RE+ EK ++QE +++K+ QQ Q L E+ EK QE+ EK +
Sbjct: 459 MREEEETMREQEEKMQKQEENMWEQEEKEWQQ---QRLPEQKEKLWEQEKMQEQEEKIWE 515
Query: 992 EEEELQQEEEQLLREER----EKRRRQE---WERQYRKKDELQQEEEQLLREEREKRRLQ 1044
+EE+++ +EE +E++ EK R QE WE++ + +D QE++ +EER +++ Q
Sbjct: 516 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRD---QEQKMWDQEERMEKKTQ 572
Query: 1045 ERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLRE-----EPE 1099
E+E++ ++EE +EEE++ ERE + R+E E +EE++Q++EE++ + E E
Sbjct: 573 EQEKKTWDQEEKMREEERM--REREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE 630
Query: 1100 KRRRQERERQCREEEELQQEEEQLLREEREKRRRQEL--ERQYREEEEVQQEEEQLLREE 1157
++ +++ E+ +EE++ ++EE++ ++R ++++L + +E+E++Q++EE++ +E
Sbjct: 631 EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQE 690
Query: 1158 PEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDE 1217
+++ QE E++ ++E++++EE +RE ++K R+E E +EE++Q Q+ K + ++E
Sbjct: 691 KMEKKTQEQEKKTWDQEKMREEES--MREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 748
Query: 1218 DQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQER 1277
+ WE E++ ++ K++ + R EQ +L + + Q + + EQ+E+
Sbjct: 749 E-------MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK------IWEQEEK 795
Query: 1278 DREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRK 1337
R+QE + Q ++ +EE++ +E+K + ++ +E+++ +E + + ++ + K
Sbjct: 796 MRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEK 855
Query: 1338 FREEEQLLQEREEQPLRRQERDRKFREEELRHQEQ 1372
+ +E+ ++E+EE+ +R QE + +EE++R QE+
Sbjct: 856 MQGQEEKMREQEEK-MRGQEEKMREQEEKMRGQEE 889
Score = 305 bits (782), Expect = 2e-82
Identities = 218/796 (27%), Positives = 456/796 (57%), Gaps = 80/796 (10%)
Query: 1065 GEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLL 1124
GE ++ R L + ELQ+ + + R E + R+ L+ +
Sbjct: 162 GESKDLAGR--LHHSWHFAGELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTIT 219
Query: 1125 REEREKRR---RQELERQYREEEEVQQEEEQLLRE-EPEKRRRQELERQYREEEELQQEE 1180
EE +K+ +++L E+ E+Q ++L R+ E K +++ +EE +QEE
Sbjct: 220 NEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEE 279
Query: 1181 EQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKV 1240
E LRE+++K R++ E+ +R+EE L+ Q+ K R ++E W EK ++ ++
Sbjct: 280 E--LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKM-------WRQEKRLREQEKEL 330
Query: 1241 YCKGRENEQFRQL-EDSQLRDRQSQ-QDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQ 1298
EQ ++L E +LR+++ Q Q+ + + EQ+E+ REQE + W+Q +R + +E+Q
Sbjct: 331 ------REQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 384
Query: 1299 LEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQER 1358
+ +EQK + +R +++++L E+EE+ R QE + EQ+ + REE+ ++ QE+
Sbjct: 385 MREQEQKMRDQEERMWEQDERL--REKEERMREQE-----KMWEQVEKMREEKKMQEQEK 437
Query: 1359 DRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFRE 1418
+ +EE++ +EE+R+R ERE+K +EE+ +R E+E+++++ + + +
Sbjct: 438 KTRDQEEKM----------QEEERIR--EREKKMREEEETMR--EQEEKMQKQEENMWEQ 483
Query: 1419 EEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER-EEQQ 1477
EE++ +Q + + +Q + QE+E K E+E+++R + +E++ QE+ EQ+
Sbjct: 484 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 543
Query: 1478 LHRQERDRKFLEEEQQLRRQER--DRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQ 1535
E++ K ++EQ++ QE ++K +EQE ++ + E K EEE+ ++R++K +
Sbjct: 544 DQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERM---REREKKMRE 600
Query: 1536 EEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQER 1595
EE+ +R QE ++ Q+++ K +E+E+ E+EE+ QE++ K +E+K+ QE++
Sbjct: 601 EEEMMREQE---EKMQEQEEKMQEQEEKMWEQEEKM---QEQEEKMWEQEEKMWEQEEK- 653
Query: 1596 KFMEDEQQLRRQEGQ--QQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLR 1653
M ++Q+L Q+ + + + + K +E E+ + E+E+ + QE+++K ++E
Sbjct: 654 --MWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQE---- 707
Query: 1654 RQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEE 1713
+ RE++ +R++K REEE++++E EE + QE++ K +E+E+++ QE E+ + QEE
Sbjct: 708 -KMREEESMREREKKMREEEEMMREQEE---KMQEQEEKMQEQEEEMWEQE-EKMWEQEE 762
Query: 1714 QQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKF 1773
+ +Q L ++E+ E QEQ + E+ K+ ++E+ + +E+++R QE +
Sbjct: 763 KMWEQQRLPE--QKEKLWEHEKMQEQEKIWEQEEKMRDQEE-KMRGQEEKMRGQEEKMRG 819
Query: 1774 REEEQLRQER----EEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQ 1829
+EE+ QE +E+++ QE ++ + +EE++ ++ + Q+ + ++++ K R +EE+++
Sbjct: 820 QEEKMWGQEEKMWGQEEKMWGQE-EKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMR 878
Query: 1830 LEEQEQRLRQERDRQY 1845
EQE+++R + ++ Y
Sbjct: 879 --EQEEKMRGQEEKIY 892
Score = 305 bits (781), Expect = 3e-82
Identities = 221/761 (29%), Positives = 440/761 (57%), Gaps = 73/761 (9%)
Query: 987 EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
+K R EEL +E + L E R + +KK+ QE+ L E+ + +L +
Sbjct: 193 KKADRYIEELTKERDAL---SLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVK 249
Query: 1047 ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER 1106
E + + E + L + +T QE +R+EEEL+++E+++ ++E + R++ER
Sbjct: 250 ELKRK------LERAKFLLPQVQTNTLQE--EMWRQEEELREQEKKIRKQEEKMWRQEER 301
Query: 1107 ERQ----CREEEELQQEEEQLLREEREKRRRQELE----RQYREEEEVQQEEEQLLREEP 1158
R+ RE+EE +E+ LRE+ ++ R QE E ++ RE+EE QE+E+ + E+
Sbjct: 302 LREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQE 361
Query: 1159 EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDED 1218
EK R QE E+ +R+EE L ++E+Q +RE+++K R + ER + ++E L +++++R R+++
Sbjct: 362 EKMREQE-EKMWRQEERLWEQEKQ-MREQEQKMRDQEERMWEQDERL--REKEERMREQE 417
Query: 1219 QRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQ-QDLQHLLGEQQER 1277
+ + + EK+ ++ K R+ E+ Q E+ ++R+R+ + ++ + + EQ+E+
Sbjct: 418 KMWEQVEKMREEKKMQEQEKKT----RDQEEKMQ-EEERIREREKKMREEEETMREQEEK 472
Query: 1278 DREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRK 1337
++QE W+Q ++ E +Q EQKE K QE+++ + E+ EEK R QE
Sbjct: 473 MQKQEENMWEQEEK---EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ-EEKIRDQE--EM 526
Query: 1338 FREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQ 1397
+ +E+++ + ++ +R QE +EE++R QEQ EE + QE+E+K +E+
Sbjct: 527 WGQEKKMWR---QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEE 583
Query: 1398 QLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQ 1457
++R +ER ++R++K REEE+ + QE + +EQ+ + QE+E K E+E+++ Q
Sbjct: 584 KMREEER----MREREKKMREEEEMMREQEE----KMQEQEEKMQEQEEKMWEQEEKM-Q 634
Query: 1458 ERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKF 1517
E+ K E+E+ + E+EE+ +Q + E++++L E K +EQE + QE E K
Sbjct: 635 EQEEKMWEQEEKMWEQEEKMWEQQ----RLPEQKEKLWEHE---KMQEQE-KMQEQEEKI 686
Query: 1518 LEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQER 1577
E+E+ + Q Q K +++++R +E ++R++K REEE++ +E+EE+ ++E
Sbjct: 687 WEQEKMEKKTQEQEKKTWDQEKMREEE----SMREREKKMREEEEMMREQEEKMQEQEE- 741
Query: 1578 DRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQER-EEQQL 1636
+++EQ+ EQE K E E+++ QQ+L +++++ + ++ QE+ EQ+
Sbjct: 742 ----KMQEQEEEMWEQEEKMWEQEEKMWE---QQRLPEQKEKLWEHEKMQEQEKIWEQEE 794
Query: 1637 HRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREE 1696
++++ K +E ++R Q E+++R ++ + +EE++ G+E+++ QE +EE
Sbjct: 795 KMRDQEEKMRGQEEKMRGQ--EEKMRGQEEKMWGQEEKMW--GQEEKMWGQEEKMWGQEE 850
Query: 1697 EQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ 1737
+ + + Q +E K ++E+++R QE E+ +EE++R + E+
Sbjct: 851 KMEEKMQGQEEKMREQEEKMRGQE-EKMREQEEKMRGQEEK 890
Score = 302 bits (774), Expect = 2e-81
Identities = 224/783 (28%), Positives = 431/783 (55%), Gaps = 92/783 (11%)
Query: 340 RREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQ 399
R ++ +R ++L +E++ E EE +++ +++L + + E QL ++
Sbjct: 191 RHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKE 250
Query: 400 QLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLK 459
R+ L R + L + Q Q+ QEEE EQ+ + ++E+++ R++E R
Sbjct: 251 LKRK---LERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLR---- 303
Query: 460 REEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRL 519
E+E + EQE + R+E+ L+ +E+E REQ++ REQ+E REQ
Sbjct: 304 -EQEGKMREQEEKMW---------RQEKRLREQEKELREQEKEL-----REQKELREQEE 348
Query: 520 KRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER--REQRLK-REQEER-- 574
+ QE+EE++ + +++ REQEE+ + R+EE+ EQE+ REQ K R+QEER
Sbjct: 349 QMQEQEEKMWE----QEEKMREQEEK----MWRQEERLWEQEKQMREQEQKMRDQEERMW 400
Query: 575 -RDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEER--REQRLKREEPEEERRQ 631
+D+ L+ +EER REQE+ EQ K E ++++++E+ R+Q K +E E R +
Sbjct: 401 EQDERLREKEERM-----REQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRER 455
Query: 632 QLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQE 691
+ EE+E R+Q+ E+ +++E+ + +EE+E +QRL + E+ ++++ E+E++
Sbjct: 456 EKKMREEEETMREQE---EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 512
Query: 692 QARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEE 751
+ K R + W ++ K++ + + +E + + EQEEK R +E ++ W +E
Sbjct: 513 IWEQEEKIRDQEEMW-------GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM-WDQE 564
Query: 752 ERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFL 811
ER ++ QE+E++ W EEK + +RE+ E EE+ Q ++ +
Sbjct: 565 ERMEKKTQEQEKKT-----WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 619
Query: 812 PEEEEKEQRRRQRREREKELQFLEEEEQLQRRERA---QQLQEEEDGLQEDQERRRSQEQ 868
E+EEK + ++ + ++E + +EE+ ++ E+ Q+L E+++ L E ++ + ++
Sbjct: 620 QEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKM 679
Query: 869 RRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQER 928
+ ++ W+ E+ K+ + QE+ +Q+ ++EEE EREK+ R+E+E
Sbjct: 680 QEQEEKIWEQEKMEKKTQE--------QEKKTWDQEKMREEES---MREREKKMREEEEM 728
Query: 929 QYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK 988
RE+E+ QE+E+ ++E+ E+ QE E+ + +++K+ E+Q L E+ EK E
Sbjct: 729 M-REQEEKMQEQEEKMQEQEEEMWEQE-EKMWEQEEKMW--EQQRLPEQKEKLWEHE--- 781
Query: 989 KYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERER 1048
K +E+E++ ++EE+ +R++ EK R QE E + +E+ +R + EK QE E+
Sbjct: 782 KMQEQEKIWEQEEK-MRDQEEKMRGQE---------EKMRGQEEKMRGQEEKMWGQE-EK 830
Query: 1049 QYREEEELQQEEEQLLG-EERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERE 1107
+ +EE++ +EE++ G EE+ + Q E + R++EE + +E+ +RE+ EK R QE +
Sbjct: 831 MWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Query: 1108 RQC 1110
C
Sbjct: 891 IYC 893
Score = 295 bits (754), Expect = 4e-79
Identities = 204/692 (29%), Positives = 409/692 (59%), Gaps = 50/692 (7%)
Query: 96 DEEKRARCDGKESL-LQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154
+E K+ + +E L L + + E Q + R+LE + + Q Q L E +
Sbjct: 221 EELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLE----RAKFLLPQVQTNTLQEEMWR 276
Query: 155 SEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQL---QSCKGHETEEFPDEEQLR 211
E++ R +++ ++++E++WRQ + +E+E + E+E+ Q + E E+ E++
Sbjct: 277 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKE 336
Query: 212 RRELLELRRKGREEKQQQRRER---QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQ 268
RE ELR + EE+ Q++ E+ Q+ +E+EEK WR+ E + +E++ ++E+ R
Sbjct: 337 LREQKELREQ--EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD 394
Query: 269 RELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERR 328
+E + E+ R E++E RE+++ +Q +++R E+++ ++QE++ R+Q+E+ +E++ R
Sbjct: 395 QEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKM-QEQEKKTRDQEEKMQEEERIR 453
Query: 329 EQQEE-RREQQLRREQEERREQQLRR--EQEEERREQQLRREQEEERREQQLRREQQLRR 385
E++++ R E++ REQEE+ ++Q EQEE+ +QQ EQ+E+ EQ+ +EQ+
Sbjct: 454 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQE--- 510
Query: 386 EQQLRREQQLRREQQL--RREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR 443
E+ +E+++R ++++ + ++ R+E+ +E Q+ +++ R+QE++ +Q+ E++
Sbjct: 511 EKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKK 570
Query: 444 EQRLKREQEERRDWLKREEE-TERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQER 502
Q +++ ++ + ++ EE ER ++ R ++++ R+QEE+ +E+ K++E+E E+
Sbjct: 571 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQE--EKMWE 628
Query: 503 REQQLRREQEERREQRLKRQEEEERL--QQRLRSEQQLRREQEERREQ-LLKREEEKRLE 559
+E++++ ++E+ EQ K E+EE++ QQRL +++ E E+ +EQ ++ +EEK E
Sbjct: 629 QEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWE 688
Query: 560 QERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQR 619
QE+ E++ + ++++ DQ REEE ++R K+ +EE EE+ R ++E+ +EQ
Sbjct: 689 QEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREE--------EEMMREQEEKMQEQE 740
Query: 620 LKREEPEEERRQQLLKSEEQEERR-QQQLRREQQERREQRLKREEEEERLEQRLK-REHE 677
K +E EEE +Q K EQEE+ +QQ EQ+E+ + K +E+E+ EQ K R+ E
Sbjct: 741 EKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQE 800
Query: 678 EERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQE--- 734
E+ R Q EE+ E+++ + K W E + ++ K++ + K GQ + E
Sbjct: 801 EKMRGQ---EEKMRGQEEKMRGQEEK-MWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKM 856
Query: 735 --QEEKRRRRESELQWQEEERAHRQQQEEEQR 764
QEEK R +E +++ QEE+ ++QEE+ R
Sbjct: 857 QGQEEKMREQEEKMRGQEEK---MREQEEKMR 885
Score = 287 bits (735), Expect = 6e-77
Identities = 240/879 (27%), Positives = 483/879 (54%), Gaps = 135/879 (15%)
Query: 1110 CREEEELQQEEEQLLREEREKRRRQELERQYREEEE--------VQQEEEQLLREEPEKR 1161
C E+ QQ QL E++ + QE R+ E ++ + E E L +
Sbjct: 66 CHSPEDTQQNRAQLKEEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAA 125
Query: 1162 RRQE-------------LERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQR- 1207
R+ E L + +R L L+ E + + ELQR
Sbjct: 126 RKFEDGNLGTPSSFNLALSQAFRGSP-LGCVSTSLIPGESKDLAGRLHHSWHFAGELQRA 184
Query: 1208 -------QKRKQRYRDE--DQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDS-- 1256
K+ RY +E +R L + N + + ++ K E ++ L +S
Sbjct: 185 LSAVSTRHKKADRYIEELTKERDALSLELY---RNTITNEELKKKNAELQEKLPLAESEK 241
Query: 1257 ---QLRDRQSQQDLQH---LLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRR 1310
QL ++ ++ L+ LL + Q ++E W+Q + +E+++ ++E+K ++
Sbjct: 242 SEIQLNVKELKRKLERAKFLLPQVQTNTLQEEM--WRQEEELREQEKKIRKQEEKMWRQE 299
Query: 1311 DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQ 1370
+R ++E ++ E+EEK RQE ++ RE+E+ L+E+E++ LR Q ++ RE+E + Q
Sbjct: 300 ERLREQEGKM--REQEEKMWRQE--KRLREQEKELREQEKE-LREQ---KELREQEEQMQ 351
Query: 1371 EQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDR 1430
EQ K E+E+++R QE E+ + +EE R E+E+Q+R+ +++K R++E+++ E+D
Sbjct: 352 EQEEKMWEQEEKMREQE-EKMWRQEE---RLWEQEKQMRE-QEQKMRDQEERM--WEQDE 404
Query: 1431 KFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEE 1490
+ RE+E+++R QE K E+ +++R+E+ K +E+E+ +++EE+ ++E
Sbjct: 405 RLREKEERMREQE---KMWEQVEKMREEK--KMQEQEKKTRDQEEK-----------MQE 448
Query: 1491 EQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQ----RQRKFLQEEQQLRRQERG 1546
E+++R ER++K RE+E +E E K ++E+ + Q+ +Q++ +++++L QE+
Sbjct: 449 EERIR--EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM 506
Query: 1547 QQRRQ---DRDRKFREEEQL--------RQER-EEQQLSRQERDRKFRLEEQKV------ 1588
Q++ + +++ K R++E++ RQE+ EQ+ E++ K R +EQK+
Sbjct: 507 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 566
Query: 1589 ---RRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKF 1645
+ QEQE+K + E+++R +E +ER++K RE+E++++E+EE+ QE++ K
Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERM----REREKKMREEEEMMREQEEKM---QEQEEKM 619
Query: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEE---QQLRRQERDRKFREEEQQLRR 1702
E+E ++ QE + Q +++ K E+E+ + E EE +Q R E+ K E E +
Sbjct: 620 QEQEEKMWEQEEKMQ---EQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHE---KM 673
Query: 1703 QERERKFLQEEQQLRRQELERKFREEEQLR--QETEQEQLRRQERYRKILEEEQLRPERE 1760
QE+E+ QEE+ ++++E+K +E+E+ QE +E+ +ER +K+ EEE++ E+E
Sbjct: 674 QEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQE 733
Query: 1761 ----EQQLRRQERDRKFREEEQLRQEREE---QQLRSQESDRKFREEEQLRQERE--EQQ 1811
EQ+ + QE++ + E+E+ E+EE +Q R E K E E+++++ + EQ+
Sbjct: 734 EKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQE 793
Query: 1812 LRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQ-FATQEKSRREEQELWQEEE- 1869
+ + ++ K R +EE+++ QE+++R + ++ + EE+ + +EK +E+++W +EE
Sbjct: 794 EKMRDQEEKMRGQEEKMR--GQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEK 851
Query: 1870 -QKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
+++ Q +E K+RE+ + + +EE+ Q +++ QE K
Sbjct: 852 MEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 286 bits (733), Expect = 1e-76
Identities = 207/757 (27%), Positives = 428/757 (56%), Gaps = 81/757 (10%)
Query: 1165 ELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLK 1224
EL+R ++ ++ + E ++R YR + ++ K++ + ++ L
Sbjct: 180 ELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNT--ITNEELKKKNAELQEKLPLA 237
Query: 1225 WQWEPEKENAVRDNKVYCKGRENEQFR--QLEDSQLRDRQSQQDLQHLLGEQQERDREQE 1282
E EK + K + E +F Q++ + L++ +Q+ + L EQ+++ R+QE
Sbjct: 238 ---ESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE--LREQEKKIRKQE 292
Query: 1283 RRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEE 1342
+ W+Q +R E+E RE++++ R++++ +E+++ LRE+ +E R ++E RE+E
Sbjct: 293 EKMWRQEER-LREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKE----LREQE 347
Query: 1343 QLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQ 1402
+ +QE+EE + E++ K RE+E + Q + E+E+++R QE++ + +Q+ R
Sbjct: 348 EQMQEQEE---KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR----DQEERMW 400
Query: 1403 EREQQLRQDRDRKFREEE--QQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERH 1460
E++++LR+ +R +E+ +Q+ + ++K +E+E++ R QE + ++EE+++R ER
Sbjct: 401 EQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK---MQEEERIR-ERE 456
Query: 1461 RKFREEEQLLQEREEQQLHRQERDRKFLEEE-QQLRRQERDRKFREQELRSQEPERKFLE 1519
+K REEE+ ++E+EE+ ++E + E+E QQ R E+ K EQE + QE E K E
Sbjct: 457 KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE-KMQEQEEKIWE 515
Query: 1520 EEQQLHRQQ----------RQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE 1569
+E+++ Q+ RQ K ++E Q+ QE ++ R + + +EE++ ++ +E
Sbjct: 516 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE--EKMRDQEQKMWDQEERMEKKTQE 573
Query: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEG----QQQLRQERDRKFREDE 1625
Q+ +++ K R EE R +E+E+K E+E+ +R QE Q++ QE++ K E E
Sbjct: 574 QEKKTWDQEEKMREEE---RMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE 630
Query: 1626 QLLQEREEQQLHRQERDRKFLEEEPQLRRQER-----EQQLRHDR---DRKFREEEQLLQ 1677
+ +QE+EE+ ++E K E+E ++ Q+R E+ H++ K +E+E+ +
Sbjct: 631 EKMQEQEEKMWEQEE---KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIW 687
Query: 1678 EGEEQQLRRQERDRKFREEEQQLRRQ---ERERKFLQEEQQLRRQELERKFREEEQLRQE 1734
E E+ + + QE+++K ++E+ + ERE+K +EE+ +R QE K +E+E+ QE
Sbjct: 688 EQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQE--EKMQEQEEKMQE 745
Query: 1735 TEQEQLRRQERY----RKILEEEQLRPEREE--QQLRRQERDRKFREEEQLRQEREEQQL 1788
E+E ++E+ K+ E+++L ++E+ + + QE+++ + +EE++R + E+++
Sbjct: 746 QEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQ--EEKM 803
Query: 1789 RSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAE 1848
R QE K R +E+ + +EE+ +++ W +E+ ++E+ QE + + +
Sbjct: 804 RGQEE--KMRGQEEKMRGQEEKMWGQEEK----MWGQEEKMWGQEEKMWGQEEKMEEKMQ 857
Query: 1849 EQFATQEKSRREEQELWQEEEQKRRQERERKLREEHI 1885
Q +EK R +E+++ +EE+ R QE + + +EE I
Sbjct: 858 GQ---EEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 286 bits (733), Expect = 1e-76
Identities = 188/627 (29%), Positives = 369/627 (58%), Gaps = 60/627 (9%)
Query: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE 156
EEK R + + + + +E++++ + R E+E R ++K +++EL E EEQ +
Sbjct: 292 EEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQ 351
Query: 157 KQERL--EQRDRQRRDEE-LWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRR 213
+QE EQ ++ R EE +WRQ + E+E++ E+EQ K + EE E+ R R
Sbjct: 352 EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ----KMRDQEERMWEQDERLR 407
Query: 214 ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE--L 271
E +EE+ +++ + ++V + EEK+ +++E R +EEK+QEEE R+RE +
Sbjct: 408 E--------KEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKM 459
Query: 272 QEEEEQLR----KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER 327
+EEEE +R K+++QE QEE++ QQ+ EQ+ + ++E+ +EQ+E+ EQ+E+
Sbjct: 460 REEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 519
Query: 328 REQQEER--REQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR 385
QEE +E+++ R+++ R ++ EQEE+ R+Q+ + +EER E++ + +++
Sbjct: 520 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTW 579
Query: 386 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ 445
+Q E+++R E+++R RE+++R E+++ REQ+ + +++EE+ Q+ E++ EQ
Sbjct: 580 DQ----EEKMREEERMRE-----REKKMREEEEMMREQEEKMQEQEEKM-QEQEEKMWEQ 629
Query: 446 RLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQ 505
K +++E + W + E+ E+ E+ +Q+L E++ + W E E+ +EQ++ +EQ
Sbjct: 630 EEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP----EQKEKLW---EHEKMQEQEKMQEQ 682
Query: 506 QLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ--LLKREEEKRLEQERR 563
+ + ++E+ E++ + QE++ Q+++R E+ +R +++ RE+ +++ +EEK EQE +
Sbjct: 683 EEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEK 742
Query: 564 EQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERL-EQEER-REQRLK 621
Q + E E+ +++ ++EE+ +Q+ EQ+E+L + K +E E++ EQEE+ R+Q K
Sbjct: 743 MQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEK 802
Query: 622 REEPEEERRQQLLKSEEQEERR----------------QQQLRREQQERREQRLKREEEE 665
EE+ R Q K QEE+ Q++ Q+E+ E++++ +EE+
Sbjct: 803 MRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEK 862
Query: 666 ERLEQRLKREHEEERREQELAEEEQEQ 692
R ++ R EE+ REQE QE+
Sbjct: 863 MREQEEKMRGQEEKMREQEEKMRGQEE 889
Score = 264 bits (675), Expect = 6e-70
Identities = 201/702 (28%), Positives = 400/702 (56%), Gaps = 119/702 (16%)
Query: 1310 RDRKSQEEKQLLREERE----EKRRRQETDRKFREEEQLLQEREEQPLRRQERDR-KFRE 1364
R +K+ + L +ER+ E R T+ + +++ LQE+ PL E+ +
Sbjct: 191 RHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEK--LPLAESEKSEIQLNV 248
Query: 1365 EELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLS 1424
+EL+ + + KFL + + + E ++E++LR E+E+++R+ ++ +R+EE+
Sbjct: 249 KELKRKLERAKFLLPQVQTNTLQEE--MWRQEEELR--EQEKKIRKQEEKMWRQEERL-- 302
Query: 1425 RQERDRKFREEEQQVRRQER-----ERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLH 1479
+E++ K RE+E+++ RQE+ E++ E+E++LR++ ++ RE+E+ +QE+EE+
Sbjct: 303 -REQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQ--KELREQEEQMQEQEEKMWE 359
Query: 1480 RQER-----------DRKFLEEEQQLRRQE---RDRKFR--EQELRSQEPERKFLEEE-- 1521
++E+ + + E+E+Q+R QE RD++ R EQ+ R +E E + E+E
Sbjct: 360 QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM 419
Query: 1522 -QQLHRQQRQRKFLQEEQQLRRQE---RGQQRRQDRDRKFREEEQLRQEREEQQLSRQER 1577
+Q+ + + ++K ++E++ R QE + ++R ++R++K REEE+ +E+EE+ ++E
Sbjct: 420 WEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 479
Query: 1578 D--------RKFRLEEQK------VRRQEQERKFMEDEQQLRRQE----------GQQQL 1613
++ RL EQK + QEQE K E E+++R QE Q+++
Sbjct: 480 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 539
Query: 1614 RQERDR------KFREDEQLLQEREEQ-QLHRQERDRKFLEEEPQLRRQEREQQLRHDRD 1666
R++ D+ K R+ EQ + ++EE+ + QE+++K ++E ++R +ER +R+
Sbjct: 540 REQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEER----MRERE 595
Query: 1667 RKFREEEQLLQEGE----EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELE 1722
+K REEE++++E E EQ+ + QE++ K E+E+++ QE+E K ++E+++ Q E
Sbjct: 596 KKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKM--QEQEEKMWEQEEKMWEQ--E 651
Query: 1723 RKFREEEQLRQETE--------QEQLRRQERYRKILEEEQLRPEREEQQLR--------- 1765
K E+++L ++ E QEQ + QE+ KI E+E++ + +EQ+ +
Sbjct: 652 EKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMRE 711
Query: 1766 ---RQERDRKFREEEQLRQERE----EQQLRSQESDRKFREEEQLRQERE----EQQLRP 1814
+ER++K REEE++ +E+E EQ+ + QE + + E+E+ E+E EQQ P
Sbjct: 712 EESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLP 771
Query: 1815 QQRDGKYRWE--EEQLQLEEQEQRLRQERDRQYRAEEQFATQ-EKSRREEQELWQEEEQK 1871
+Q++ + E +EQ ++ EQE+++R + ++ EE+ Q EK R +E+++W +EE+
Sbjct: 772 EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM 831
Query: 1872 RRQERERKLREEHI--RRQQKEEQRHRQVGEIKSQEGKGHGR 1911
QE + +EE + + ++ EE+ Q +++ QE K G+
Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQ 873
Score = 258 bits (659), Expect = 4e-68
Identities = 173/602 (28%), Positives = 358/602 (59%), Gaps = 51/602 (8%)
Query: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQ-EQERELAEGEEQ 154
++EK R KE Q +E++++ E ++ E+E R ++++ QE L E E+Q
Sbjct: 325 EQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 384
Query: 155 SEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRE 214
+QE+ + RD ++E +W Q + +E+EER E+E++ + E+ +E++++ +E
Sbjct: 385 MREQEQ-KMRD---QEERMWEQDERLREKEERMREQEKM----WEQVEKMREEKKMQEQE 436
Query: 215 LLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE----PQRQRE 270
+K R+++++ + E + R E EK+ R+ E +R++EEK+Q++E Q ++E
Sbjct: 437 -----KKTRDQEEKMQEEERIR----EREKKMREEEETMREQEEKMQKQEENMWEQEEKE 487
Query: 271 LQEEE--EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERR 328
Q++ EQ KL QE +E++E+ +Q+ R+Q+ QE++ Q++ R ++ +
Sbjct: 488 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 547
Query: 329 EQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQ 388
EQ+E+ R+Q+ + +E R ++ +EQE++ +Q+ + +EE RE RE+++R E++
Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRE----REKKMREEEE 603
Query: 389 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLK 448
+ REQ+ + ++Q + Q+ + E+ +E++++ +++ EQEE+ EQ+ E+ +QRL
Sbjct: 604 MMREQEEKMQEQEEKMQE-QEEKMWEQEEKMQEQEEKMWEQEEKMWEQE-EKMWEQQRLP 661
Query: 449 REQEERRDWLKREEETERHEQERR---KQQLKRDQEEERRERWLKLEEEERREQQ--ERR 503
++E+ + K +E+ + EQE + ++++++ +E+ ++ W ++E+ RE++ R
Sbjct: 662 EQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTW---DQEKMREEESMRER 718
Query: 504 EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR 563
E+++R E+E REQ K QE+EE++Q++ E+++ ++E+ EQ K E++RL E++
Sbjct: 719 EKKMREEEEMMREQEEKMQEQEEKMQEQ---EEEMWEQEEKMWEQEEKMWEQQRL-PEQK 774
Query: 564 EQRLKREQEERRDQLLKREEERRQQRLK-REQEERLEQRLKREEVERLEQEERREQRLKR 622
E+ + E+ + ++++ ++EE+ R Q K R QEE++ +EE R ++E+ Q K
Sbjct: 775 EKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMR---GQEEKMRGQEEKMWGQEEKM 831
Query: 623 EEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERRE 682
EE+ Q K QEE+ +++++ ++++ REQ K +EE++ RE EE+ R
Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKM-----REQEEKMRG 886
Query: 683 QE 684
QE
Sbjct: 887 QE 888
Score = 206 bits (524), Expect = 2e-52
Identities = 135/488 (27%), Positives = 287/488 (58%), Gaps = 41/488 (8%)
Query: 91 QATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQ-KRQEQERELA 149
Q + EEK+ + K++ Q+ + +E++R E + EEE R ++ K Q+QE +
Sbjct: 422 QVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 481
Query: 150 EGEEQSEKQERL--------EQRDRQRRDEELWRQRQEWQEREERRAEEEQL---QSCKG 198
E EE+ +Q+RL EQ Q ++E++W Q ++ +++EE +E+++ + +
Sbjct: 482 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 541
Query: 199 HETEEFPDEEQLRRRELLELRRKGREEKQQQRRER----QDRVFQEEE-----EKEWRKR 249
E + + EE++R +E ++ R EK+ Q +E+ Q+ +EEE EK+ R+
Sbjct: 542 QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 601
Query: 250 ETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRK 309
E ++R++EEK+QE+E + Q + ++ EQ K++ QE + QEE+ +Q + +Q R
Sbjct: 602 EEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 661
Query: 310 QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQE 369
+++E+ + E+ +EQ E+ ++QEE+ +Q + E++ + +++ +QE+ R E+ +R ++
Sbjct: 662 EQKEKLWEHEKMQEQ-EKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREK 720
Query: 370 EERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 429
+ R E+++ REQ E++++ +++ +EQ+ E+ +E+++ +++ EQQ EQ
Sbjct: 721 KMREEEEMMREQ----EEKMQEQEEKMQEQE---EEMWEQEEKMWEQEEKMWEQQRLPEQ 773
Query: 430 EEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWL 489
+E+ E HE+ + ++++ ++E+ RD +EE+ E++ R Q+ K +EE+ W
Sbjct: 774 KEKLWE--HEKMQEQEKIWEQEEKMRD---QEEKMRGQEEKMRGQEEKMRGQEEK--MWG 826
Query: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQ-QRLRSEQQLRREQEERREQ 548
+ E+ +E++ +++ QEE+ E++++ QEE+ R Q +++R +++ REQEE+
Sbjct: 827 QEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEK--- 883
Query: 549 LLKREEEK 556
++ +EEK
Sbjct: 884 -MRGQEEK 890
Score = 38.9 bits (89), Expect = 0.049
Identities = 32/109 (29%), Positives = 57/109 (52%), Gaps = 10/109 (9%)
Query: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEP-GQRRRQKRQEQ----ERELAE 150
++E++ R D +E + R QEE R E + R EE+ GQ + QE+ + E
Sbjct: 791 EQEEKMR-DQEEKM---RGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMW 846
Query: 151 GEEQSEKQERLEQRDRQRRDEELWR-QRQEWQEREERRAEEEQLQSCKG 198
G+E+ +++ Q ++ R EE R Q ++ +E+EE+ +E+ C G
Sbjct: 847 GQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIYCVG 895
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 322 bits (826), Expect = 2e-87
Identities = 444/1975 (22%), Positives = 863/1975 (43%), Gaps = 231/1975 (11%)
Query: 102 RCDGKES---LLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQER--ELAEGEEQSE 156
R DG+E LL + +E ++ R ++L + Q +K + Q+R EL+ QS+
Sbjct: 237 RMDGREPAQLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQ 296
Query: 157 KQ-ERLEQRDRQRRD--EELWRQRQEWQERE---ERRAEEEQLQ---------------- 194
KQ E E+ + R+ E L E E E R A+EE+L
Sbjct: 297 KQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEG 356
Query: 195 ----SCKGHETE-----------EFPDEEQLRR--RELLELRRKGREEKQQQRRERQDRV 237
GHE ++ D ++ R +L RR+ ++ +QQ Q+ V
Sbjct: 357 DNIAQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAV 416
Query: 238 -FQEEEEKEWRKRETVLRKEEEKLQEEEP---------QRQRELQEEEEQLRKLERQELR 287
+++ +W + LR+ +KL E Q + + +E +L + R+ELR
Sbjct: 417 NLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELR 476
Query: 288 RERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERR 347
++ + EQ+ RLRR + Q + + Q+EE++E+ ++ ER ++ L + ++
Sbjct: 477 QQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQS 536
Query: 348 EQ-----QLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402
E LR E E +L R+++ E R EQ + E L+ E
Sbjct: 537 ESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSS--SENTLKTEVADL 594
Query: 403 REQQLRRE---QQLRREQQLRREQQLRREQEEER---HEQKHEQERREQRLKREQEERRD 456
R ++ + L ++ +Q L+ E+E + + EQ R ++ + E+R
Sbjct: 595 RAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRR 654
Query: 457 WLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERRE 516
E+ T Q ++ ++ + + + R+ + EE +++ + R +Q+ Q E+
Sbjct: 655 EALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLH 714
Query: 517 QRLKRQEEEERLQQRLRSEQQLRREQE--ERREQLLKREEEKRLEQ--------ERREQR 566
Q KRQEE L + ++ ++ L RE+ E R Q ++R+ + EQ E E
Sbjct: 715 QEAKRQEEV--LARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESS 772
Query: 567 L-KREQEERRDQLLKREEERRQQRLKREQE--ERLEQRLKRE-EVERLEQEERREQRLKR 622
L + +Q+ ++ K + E + Q + + +E + + LK E + ER + E+ R+ ++
Sbjct: 773 LFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQ 832
Query: 623 -EEPEEERRQQLLKSEEQEERRQQQLRREQQERR---EQRLKR-----EEEEERLEQRLK 673
+ E+E + L + + E+ QLR + ++ R +Q L + E E+ LE RLK
Sbjct: 833 LAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLK 892
Query: 674 REHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADA-------RQSKVYSRPRKQ 726
+ E Q EEE+ QA + Q QLE+E + Q++ Q
Sbjct: 893 EQQTEMEAIQAQREEERTQAESAL------CQMQLETEKERVSLLETLLQTQKELADASQ 946
Query: 727 EGQRRRQE---QEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQR 783
+ +R RQ+ Q+ K + LQ Q +E ++ Q RD Q EE S + +
Sbjct: 947 QLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQ-EESSSLLQDK 1005
Query: 784 LSARPPLREQRERQLRAEERQQR--EQRFLPEEEEKEQRRRQRREREKE-----LQFLEE 836
+ + + E + QL A++ QR EQ + E ++ R ++E E+E L +E+
Sbjct: 1006 MDLQKQV-EDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEK 1064
Query: 837 EEQLQRRERAQQLQEEE-DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPAL 895
E++L + A ++++E L++D + + +++ + +E +++ L + L
Sbjct: 1065 EQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQL 1124
Query: 896 QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE 955
E+L E + E++ +E + Q Q R E QL E L E++ + Q
Sbjct: 1125 LEEL--EASHITEQQLRASLWAQEAKAAQLQLRLRSTESQL----EALAAEQQPGNQAQA 1178
Query: 956 RERQYRKDKKLQQKEEQLLGEEPE--------------KRRRQEREKKYREEEELQQEEE 1001
+ + LQQ + PE + + ++ L
Sbjct: 1179 QAQLASLYSALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSA 1238
Query: 1002 QLLREEREKRRRQEWERQYRK---KDELQQEEEQLLREEREKRRLQERERQYREEEELQQ 1058
+ + K + W+ Q + +D++Q+ EE+L E EK ++ + E ++LQ+
Sbjct: 1239 EAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQV------HTELQDLQR 1292
Query: 1059 EEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQ 1118
+ L + +E + + E +Q E EL + E + + RR + + + + E EL Q
Sbjct: 1293 Q----LSQNQEEKSKWE-GKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQ 1347
Query: 1119 EEEQLLREEREKRRRQELERQYRE------EEEVQQEEEQLLREEPEKRRRQELERQYRE 1172
++ L + E + +E + + EE+++ L + E +E + +E
Sbjct: 1348 AAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQE 1407
Query: 1173 EEELQ-------QEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKW 1225
+ EL+ QE LL + +R +E E + +EL++Q+ Q+ E DLK
Sbjct: 1408 QGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLK- 1466
Query: 1226 QWEPEKENAVRDNKVYCKGRENEQFRQLEDSQL---RDRQSQQDLQHLLGEQQERDREQE 1282
K N D + EQ ++LE + + Q+ + L Q+E+ RE E
Sbjct: 1467 -----KRNQEVD-------LQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELE 1514
Query: 1283 RRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQL-----LREEREEKRRRQETDRK 1337
+ R QR+ + +LE+++Q +R + +KQL L E EE + E +K
Sbjct: 1515 KDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQK 1574
Query: 1338 FREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRL---RRQERERKFLK 1394
+E + +E + L D + R +EL+ Q LE + QER+++
Sbjct: 1575 LIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKS 1634
Query: 1395 EEQQLR-CQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQ 1453
+ +Q+ Q +++ L QD +R R++E L +++R E+Q+ R+ + + LE+ +
Sbjct: 1635 QREQIEELQRQKEHLTQDLER--RDQELML---QKERIQVLEDQRTRQTKILEEDLEQIK 1689
Query: 1454 QLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQ-LRRQERDRKFREQELRSQE 1512
+ER R+ + QL+QER E+ + R LE + LR +E++ + +++ + +
Sbjct: 1690 LSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQ 1749
Query: 1513 PERKFLEEEQQ-LHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQ 1571
+ LE++ Q LHR+ + L +++ QQ ++ R++ +E+ L+ + +E Q
Sbjct: 1750 ELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQ 1809
Query: 1572 LSRQERDRKFRL---EEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLL 1628
+ +RD++ E+Q+ + QE+ K D Q ++ L+ ER + ++ ++
Sbjct: 1810 RALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLK-ERHGELQDHKEQA 1868
Query: 1629 QEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQE 1688
+ EE+ R + E LR + REQ+ ++Q ++ +E ++ +
Sbjct: 1869 RRLEEELAVEGRRVQALEEVLGDLRAESREQE-----KALLALQQQCAEQAQEHEVETRA 1923
Query: 1689 RDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRK 1748
+ + + L+ +++E + L+ E Q R + E E L++ + Q + +
Sbjct: 1924 LQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQH 1983
Query: 1749 ILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQERE 1808
+LE+ +L E Q + Q + E+ LR QE + +++ LR + +
Sbjct: 1984 LLEQAELSRSLEASTATLQAS----LDACQAHSRQLEEALRIQEGEI---QDQDLRYQED 2036
Query: 1809 EQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFA--TQEKSRREEQELWQ 1866
QQL Q L ++++ LR +++R+ E+ A QE +E+Q L Q
Sbjct: 2037 VQQL--------------QQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQ 2082
Query: 1867 EEEQKRRQERERKLREEHIRRQQKEEQ--RHRQVGEIKSQEGKGHGRLLEPGTHQ 1919
E E++ + + +RE + QKE++ R+ + + E H P Q
Sbjct: 2083 EREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQ 2137
Score = 290 bits (742), Expect = 9e-78
Identities = 437/1968 (22%), Positives = 841/1968 (42%), Gaps = 250/1968 (12%)
Query: 114 RQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEEL 173
R EE+Q+R E + Q R E+ + E E+L D R +EL
Sbjct: 102 RLEEEQQRCESL--------AEVNTQLRLHMEKADVVNKALREDVEKLTV-DWSRARDEL 152
Query: 174 WRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRER 233
R+ +WQ +E KG+ E L R E++ RR E K R+
Sbjct: 153 MRKESQWQMEQE---------FFKGYLKGEHGRLLSLWR-EVVTFRRHFLEMKSATDRDL 202
Query: 234 QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ-EEEEQLRKL--ERQELRRER 290
+ + E + T + Q EP + E QL L + QEL +E
Sbjct: 203 ME--LKAEHVRLSGSLLTCCLRLTVGAQSREPNGSGRMDGREPAQLLLLLAKTQELEKEA 260
Query: 291 QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQE------ 344
E Q+ +L+ + L + + ++R + Q +++ + E+ + LR E
Sbjct: 261 HERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNH 320
Query: 345 ----ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRRE-- 398
E R QEE+ QQ+ ++ + E+ Q E L + + +
Sbjct: 321 TELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQFD 380
Query: 399 -QQLRREQQLRREQQLRREQQLR--REQQLRREQEEERHEQKHEQERREQRLKREQEER- 454
Q + L R RR Q ++ R+Q ++ +Q+H+Q E + R++ ++
Sbjct: 381 YQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKL 440
Query: 455 ---RDWLKREEETERHEQER--RKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR 509
RD L + + E + ++++L + EE R++ LE+E R ++ E QL+
Sbjct: 441 TGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQG 500
Query: 510 E-----QEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERRE 564
+ +EE++E+ E ERLQ+ L L +Q E +L+ E LE E
Sbjct: 501 DSAQGQKEEQQEELHLAVRERERLQEMLMG---LEAKQSESLSELITLREA--LESSHLE 555
Query: 565 QRLKREQEERRDQLLKREEER------RQQRLKREQEERLEQRLKRE---EVERLEQEER 615
L R+++ L R E+ + LK E + +K E L++
Sbjct: 556 GELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGL 615
Query: 616 REQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKRE 675
+Q L+ EE Q + E E+ + L+ + E ++R E+ LE +L++
Sbjct: 616 NQQLLQLEE----ENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKA 671
Query: 676 HEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQ 735
E Q + QE+ +E I+ ++ + + Q E+ A + +++ ++QE R Q
Sbjct: 672 EEAGAELQADLRDIQEE-KEEIQKKLSESRHQQEA-ATTQLEQLHQEAKRQEEVLARAVQ 729
Query: 736 EEKRRRRES---ELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLRE 792
E++ RE E++ Q ER RQ E+ + + + E +Q+ S +
Sbjct: 730 EKEALVREKAALEVRLQAVER-DRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKG 788
Query: 793 QRERQLR----AEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQ 848
Q E Q++ A+E Q E R L E + E+ + E+E R+ AQ
Sbjct: 789 QLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQA------------EQERDAAARQLAQA 836
Query: 849 LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE 908
QE + L++ + + + +KW E++R H Q++L K + L+
Sbjct: 837 EQEGKTALEQQKAAHEKEVNQLREKW------EKERSWH--------QQELAKALESLER 882
Query: 909 EEEELQREEREKRRRQEQERQYREEEQLQQEEEQL-LREEREKRRRQERERQYRKDKKLQ 967
E+ EL+ +E++ E + REEE+ Q E ++ E EK R E + K+L
Sbjct: 883 EKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELA 942
Query: 968 QKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKK-DEL 1026
+QL E+ R+ + +K +E+E + QL +RE + E RQ+R L
Sbjct: 943 DASQQL-----ERLRQDMKVQKLKEQETTGILQTQLQEAQRELK---EAARQHRDDLAAL 994
Query: 1027 QQEEEQLLREERE-KRRLQERERQYREEEELQQEEEQLLGEE-RETRRRQELERQYRKEE 1084
Q+E LL+++ + ++++++ + Q +++ Q+ EQ + E+ RET+ ++++ +E+
Sbjct: 995 QEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREK 1054
Query: 1085 E------LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQL------LREEREKRR 1132
+++E+ L+ +E + R+QE ++ +E Q E+++L LR+E +++
Sbjct: 1055 ASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKE 1114
Query: 1133 RQEL--ERQYREEEEVQQEEEQLLREE--PEKRRRQELERQYREEEELQQEEEQLLREEQ 1188
L E Q EE E EQ LR ++ + +L+ + R E + E L E+Q
Sbjct: 1115 ADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTES---QLEALAAEQQ 1171
Query: 1189 EKRRQERERQYREEEELQRQ------KRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYC 1242
+ + + Q +Q + + + W EP++ A ++
Sbjct: 1172 PGNQAQAQAQLASLYSALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGA---RSLFK 1228
Query: 1243 KG---------RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHF 1293
+G +L + +Q++ L+ + + +ER + E + Q
Sbjct: 1229 RGPLLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQ 1288
Query: 1294 PEEEQLEREEQKEAKRRDRKSQEEKQLLREER-----EEKRRRQETDRKFREEEQLLQER 1348
+ QL + +++++K +++ E +L+ + + RR E R + E+ L +
Sbjct: 1289 DLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQA 1348
Query: 1349 EEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQL 1408
++ L Q + E R Q LEE+ R R + LK E+ +ER Q L
Sbjct: 1349 AKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALK---LKNEEVESERERAQAL 1405
Query: 1409 RQDRDRKFREE---EQQLSRQERDRKFREEEQ-----QVRRQERERKFLEEEQQLRQERH 1460
++ + K + ++ L+ + REEE Q++ E++R+ + +L
Sbjct: 1406 QEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDL 1465
Query: 1461 RKFREEEQLLQEREEQQLHR------------QERDRKFLEEEQQLRRQERDRKFREQEL 1508
+K R +E LQ+ + Q+L + QER++K + +Q+R E+DR+ + L
Sbjct: 1466 KK-RNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVL 1524
Query: 1509 RSQ--EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE 1566
Q E E+K E Q + Q +K L + L + + + +K +E L +
Sbjct: 1525 EHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKE--LEGQ 1582
Query: 1567 REEQQ-------LSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDR 1619
RE Q+ L +ER ++ + + ++ E + E Q R QE + Q R++ +
Sbjct: 1583 RETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQ-REQIEE 1641
Query: 1620 KFREDEQLLQ--EREEQQLHRQERDRKFLEEEPQLRRQEREQQLRH------DRDRKFRE 1671
R+ E L Q ER +Q+L Q+ + LE++ + + E+ L +R R+
Sbjct: 1642 LQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTT 1701
Query: 1672 EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQL 1731
+ QL+QE E+ + R E + + R + + Q+E QEL+ +QL
Sbjct: 1702 QRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELK------DQL 1755
Query: 1732 RQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQ 1791
Q+ Q +RK+ E L +RE++ + Q++ ++ RE+ +L+++ + QL
Sbjct: 1756 EQQL-------QGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEA 1808
Query: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYR-------WEEEQLQLEEQEQRLRQERDRQ 1844
+ R++E ++E+QQ + Q+ K + E+ + L+E+ L+ +++
Sbjct: 1809 QRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQA 1868
Query: 1845 YRAEEQFATQ---------------EKSRREEQELWQEEEQKRRQERE-----RKLREEH 1884
R EE+ A + +SR +E+ L ++Q Q +E R L++
Sbjct: 1869 RRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSW 1928
Query: 1885 IRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQFASVPVRSSPLYE 1932
++ Q ++R +++ ++++ + HQ + R+ L E
Sbjct: 1929 LQAQAVLKERDQELEALRAES--------QSSRHQEEAARARAEALQE 1968
Score = 285 bits (729), Expect = 3e-76
Identities = 422/1902 (22%), Positives = 807/1902 (42%), Gaps = 213/1902 (11%)
Query: 91 QATGLDEEKRARCDGKESLLQDRRQ-EEDQRRFEPRDRQLEEEPG--QRRRQKRQEQERE 147
Q L+EE ++ C E+ Q R + D E R L E+ + + QK +E E
Sbjct: 618 QLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAE 677
Query: 148 LAEG--EEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFP 205
L + Q EK+E ++ R +E + E +E +R EE ++ + E
Sbjct: 678 LQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEA---- 733
Query: 206 DEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEE-------EKEWRKRETVLRKEEE 258
+R + LE+R + E +Q E+ + +E E + + + K +
Sbjct: 734 ---LVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQL 790
Query: 259 KLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQ--QQRLRREQQLRRKQEEERRE 316
++Q + + +E+ + E + KLE R + ++E +Q + EQ+ + E+++
Sbjct: 791 EVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAA 850
Query: 317 QQEERREQQERREQQEERREQQLRREQE--ERREQQLRREQEEERREQQLRREQEEERRE 374
++E + +E+ E++ +Q+L + E ER + +L +E++ E + + Q EE R
Sbjct: 851 HEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERT 910
Query: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434
Q Q++ E + R L Q ++E QQL R +Q + Q+L+ EQE
Sbjct: 911 QAESALCQMQLETEKERVSLLETLLQTQKELA-DASQQLERLRQDMKVQKLK-EQETTGI 968
Query: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEE 494
Q QE + + + ++ R D +EE+ Q++ Q Q E+ + + + ++
Sbjct: 969 LQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQ---KQVEDLKSQLVAQDDS 1025
Query: 495 ERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREE 554
+R +QE +E +L+ +E R+Q ++L RE+ L+++E+
Sbjct: 1026 QRLVEQEVQE-------------KLRETQEYNRIQ------KELEREKASLTLSLMEKEQ 1066
Query: 555 EKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEE 614
+ QE R + R+D +E + +Q+ Q E L Q +K +E + L QE
Sbjct: 1067 RLLVLQEADSIRQQELSALRQDM----QEAQGEQKELSAQMELLRQEVKEKEADFLAQE- 1121
Query: 615 RREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKR 674
Q L+ E QQL S +E + QL +L+ E +LE
Sbjct: 1122 --AQLLEELEASHITEQQLRASLWAQEAKAAQL----------QLRLRSTESQLEALAAE 1169
Query: 675 EHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQE 734
+ + + + A ++ + + + +L D+ S V+ Q G R +
Sbjct: 1170 QQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGGDSAPS-VWGLEPDQNGARSLFK 1228
Query: 735 QEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQR 794
+ +E + H+ + +Q RD ++ ++ +RL+ + Q
Sbjct: 1229 RGPLLTALSAEAVASALHKLHQDLWKTQQTRDV-----LRDQVQKLEERLTDTEAEKSQV 1283
Query: 795 ERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE-EQLQRRERAQQLQE-- 851
+L+ +RQ + +EEK + ++ E EL L E LQ R R +LQ
Sbjct: 1284 HTELQDLQRQLSQ-----NQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRME 1338
Query: 852 ---EEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE 908
E + LQ +E +Q + L+ R A L+E LR + L+
Sbjct: 1339 AQGERELLQAAKENLTAQVE--------HLQAAVVEARAQASAAGILEEDLRTARSALKL 1390
Query: 909 EEEELQREEREKRRRQEQ-ERQYREEEQLQQE----EEQLLREEREKRRRQERERQYRKD 963
+ EE++ E + QEQ E + + + LQ+ + L E E + + ++ K
Sbjct: 1391 KNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQ 1450
Query: 964 KKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQ-------------QEEEQLLREEREK 1010
+++Q+ +LL + K+R QE + + + +EL+ QE EQ L +RE+
Sbjct: 1451 REMQKAALELLSLD-LKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQ 1509
Query: 1011 RRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERET 1070
R E +R+ ++ E QLL E++ + ++ + Q ++ ++ E L E E
Sbjct: 1510 IRELEKDRETQR----NVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEEN 1565
Query: 1071 RRRQELERQYRKEEELQQEEEQLLREE---PEKRRRQERERQCREEEELQQEEEQLLREE 1127
+ E +++ KE E Q+E +++ + R QE + Q + +L+ L RE
Sbjct: 1566 HHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLAREL 1625
Query: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE 1187
+E R QE++ Q + EE+Q+++E L ++ +RR QEL Q +E +Q E+Q R+
Sbjct: 1626 QE--RDQEVKSQREQIEELQRQKEHLTQD--LERRDQELMLQ---KERIQVLEDQRTRQT 1678
Query: 1188 Q--EKRRQERERQYREE-EELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV----RDNKV 1240
+ E+ ++ + RE EL Q++ + R E+ + K Q + + ++ +V
Sbjct: 1679 KILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEV 1738
Query: 1241 YCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQ--ERDREQERRRWQQRDRHFPEEEQ 1298
C+ + ++L+D Q Q L +GE REQE QQ+ + E+ +
Sbjct: 1739 ECQQEHIHELQELKDQL---EQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGE 1795
Query: 1299 LER--------EEQKEAKRRDRK----SQEEKQLLREEREEKRRRQETDRKFREEEQLLQ 1346
L+ E Q+ +RD++ QE++Q +E K + + L+
Sbjct: 1796 LKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLK 1855
Query: 1347 EREEQPLRRQERDRKFREEELRHQEQGRKFLEE---EQRLRRQERERKFLKEEQQL--RC 1401
ER + +E+ R+ EEEL + + + LEE + R +E+E+ L +QQ +
Sbjct: 1856 ERHGELQDHKEQARRL-EEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQA 1914
Query: 1402 QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQER-ERKFLEEEQQLRQERH 1460
QE E + R +D + + R + R E Q R QE R E Q+ + H
Sbjct: 1915 QEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAH 1974
Query: 1461 RKFREEEQLLQEREE--QQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFL 1518
+ +EQ L E+ E + L + + Q ++ + R QE Q+ + ++
Sbjct: 1975 AALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQ 2034
Query: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERD 1578
E+ QQL Q+ Q +++LR Q Q+R Q ++ + Q +E+Q L ++ +
Sbjct: 2035 EDVQQL-----QQALAQRDEELRHQ---QEREQLLEKSLAQRVQENMIQEKQNLGQEREE 2086
Query: 1579 RKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHR 1638
+ R Q VR E QL + +Q++ + R+ + R + + L +
Sbjct: 2087 EEIRGLHQSVR-----------ELQLTLAQKEQEILELRETQQRNNLEALPHSHKTS-PM 2134
Query: 1639 QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQ 1698
+E+ K EP+L+R E ++L+ R + RE E
Sbjct: 2135 EEQSLKLDSLEPRLQR-------------------------ELERLQAALRQTEAREIEW 2169
Query: 1699 QLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQ-ERYRKILEEEQLRP 1757
+ + Q+ Q + + + F + L +++EQ++L+ + E R+ LE+E+L
Sbjct: 2170 REKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEKERLHS 2229
Query: 1758 EREEQQLR---RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRP 1814
R E+ + E + E + Q ++ +Q E + R
Sbjct: 2230 PGATSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVARLEIDRSRL 2289
Query: 1815 QQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRA---EEQFATQEKSRREEQELWQEEEQK 1871
Q+ + + R E Q+E + ++L++E R +A E AT +++ + + K
Sbjct: 2290 QRHNVQLRSTLE--QVERERRKLKREAMRAAQAGSLEISKATASSPTQQDGRGQKNSDAK 2347
Query: 1872 RRQERERKL----REEHIRRQQKEEQRHRQVGEIKSQEGKGH 1909
E ++++ + + R+QK++ R + G H
Sbjct: 2348 CVAELQKEVVLLQAQLTLERKQKQDYITRSAQTSRELAGLHH 2389
Score = 270 bits (690), Expect = 1e-71
Identities = 453/1980 (22%), Positives = 823/1980 (41%), Gaps = 324/1980 (16%)
Query: 227 QQQRRERQDRVFQE-EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQE 285
QQQ E Q +++ + +E ++R+ L + KLQ + Q + QE E++L
Sbjct: 28 QQQMAENQAASWRKLKNSQEAQQRQATLVR---KLQAKVLQYRSWCQELEKRLEATGGPI 84
Query: 286 LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEE 345
+R EE L +R ++E++R E E Q ++ + + LR + E+
Sbjct: 85 PQRWENVEEPNLDELL----VRLEEEQQRCESLAEVNTQLRLHMEKADVVNKALREDVEK 140
Query: 346 RREQQLRREQEEERREQQLRREQE--------EERREQQLRREQQLRREQQLRREQQLRR 397
R E R+E Q + EQE E R L RE R L + R
Sbjct: 141 LTVDWSRARDELMRKESQWQMEQEFFKGYLKGEHGRLLSLWREVVTFRRHFLEMKSATDR 200
Query: 398 E-QQLRREQ---------------------------------------QLRREQQLRREQ 417
+ +L+ E L + Q+L +E
Sbjct: 201 DLMELKAEHVRLSGSLLTCCLRLTVGAQSREPNGSGRMDGREPAQLLLLLAKTQELEKEA 260
Query: 418 QLRREQ--QLRREQEEERHEQKHEQERREQRLKREQEERRDWLK-----REE----ETER 466
R ++ QL+ + + E+ E + L + Q++ D+ K RE ET
Sbjct: 261 HERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNH 320
Query: 467 HEQERRKQQLKRDQEEERRE--------RWLKLEEEERREQQERREQQLRRE-------- 510
E + L R+ +EE+ + +EE + Q E L +
Sbjct: 321 TELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQFD 380
Query: 511 -QEERREQRL------KRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR 563
Q+ + L +R++ + L+Q+L Q+ +++ +Q EE K L Q R
Sbjct: 381 YQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQW--EEEGKALRQ--R 436
Query: 564 EQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKRE 623
Q+L E++ Q + + E +RE ++ + L R+++E LEQE R +R+ E
Sbjct: 437 LQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREEL-RQQLEVLEQEAWRLRRVNVE 495
Query: 624 EPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREH-EEERRE 682
+ Q K E+QEE RE+ + L+ ++ E E RE E E
Sbjct: 496 LQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLE 555
Query: 683 QELAEEEQEQA------RERIKSRIPKWQWQLESE-ADARQSKVYSRPRKQE------GQ 729
EL +EQ + E+ + + + L++E AD R + V + G
Sbjct: 556 GELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGL 615
Query: 730 RRRQEQ-EEKRRRRESELQWQEEERAHRQQQ--EEEQRRDFTW------QWQAEEKSERG 780
++ Q EE+ + S ++ E+ R Q E E+RR+ W + Q ++ E G
Sbjct: 616 NQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAG 675
Query: 781 RQRLSARPPLREQRE--RQLRAEERQQREQRFLPEEEEKEQRRRQ-----RREREKELQF 833
+ + ++E++E ++ +E R Q+E E+ ++ +RQ R +EKE
Sbjct: 676 AELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALV 735
Query: 834 LEE---EEQLQRRER-AQQLQEEEDGLQEDQERRRS------QEQRRDQKWRWQLEEERK 883
E+ E +LQ ER Q L E+ GL +E S Q+ + + QLE + +
Sbjct: 736 REKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQ 795
Query: 884 RRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQL 943
AK +Q ++R + L E + + +ER+ RQ + + + L+Q++
Sbjct: 796 T---VTQAKEVIQGEVRCLKLELDTERSQAE-QERDAAARQLAQAEQEGKTALEQQKAAH 851
Query: 944 LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQL 1003
+E + R + E+ER + + ++L + E L E+ E R + ++ E + Q+EEE+
Sbjct: 852 EKEVNQLREKWEKERSWHQ-QELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERT 910
Query: 1004 LRE--------EREKRRRQEWERQYRKKDELQQEEEQL--LREEREKRRLQERE------ 1047
E E EK R E + + EL +QL LR++ + ++L+E+E
Sbjct: 911 QAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQ 970
Query: 1048 --------------RQYREE-EELQQEEEQLLGEERETRR-----RQELERQYRKEEELQ 1087
RQ+R++ LQ+E LL ++ + ++ + +L Q + ++
Sbjct: 971 TQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVE 1030
Query: 1088 QEEEQLLREEPEKRRRQ---ERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEE 1144
QE ++ LRE E R Q ERE+ +++E+ L+ +E + R+QEL ++ +
Sbjct: 1031 QEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQ 1090
Query: 1145 EVQQEEE------QLLREEPEKRRRQEL--ERQYREEEELQQEEEQLLR----EEQEKRR 1192
E Q E++ +LLR+E +++ L E Q EE E EQ LR ++ K
Sbjct: 1091 EAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAA 1150
Query: 1193 QERERQYREEEELQRQKRKQRYRDEDQ----------------------RSDLK------ 1224
Q + R E +L+ +Q+ ++ Q R +L
Sbjct: 1151 QLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGGDSA 1210
Query: 1225 ---WQWEPEKENAVRDNKVYCKG---------RENEQFRQLEDSQLRDRQSQQDLQHLLG 1272
W EP++ A ++ +G +L + +Q++ L+ +
Sbjct: 1211 PSVWGLEPDQNGA---RSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQ 1267
Query: 1273 EQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR-----EEREE 1327
+ +ER + E + Q + QL + +++++K +++ E +L+ +
Sbjct: 1268 KLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQS 1327
Query: 1328 KRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQE 1387
+ RR E R + E+ L + ++ L Q + E R Q LEE+ R R
Sbjct: 1328 RLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSA 1387
Query: 1388 RERKFLKEEQQLRCQEREQQLRQDRDRKFR-----EEEQQLSRQ---ERDRKFREEEQQV 1439
+ LK E+ +ER Q L++ + K +E L Q ER+ + Q+
Sbjct: 1388 LK---LKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQI 1444
Query: 1440 RRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHR------------QERDRKF 1487
+ E++R+ + +L +K R +E LQ+ + Q+L + QER++K
Sbjct: 1445 QELEKQREMQKAALELLSLDLKK-RNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKL 1503
Query: 1488 LEEEQQLRRQERDRKFREQELRSQ--EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQER 1545
+ +Q+R E+DR+ + L Q E E+K E Q + Q +K L + L +
Sbjct: 1504 TVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELE 1563
Query: 1546 GQQRRQDRDRKFREEEQLRQEREEQQ-------LSRQERDRKFRLEEQKVRRQEQERKFM 1598
+ + +K +E L +RE Q+ L +ER ++ + + ++ E +
Sbjct: 1564 ENHHKMECQQKLIKE--LEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVL 1621
Query: 1599 EDEQQLRRQEGQQQLRQERDRKFREDEQLLQ--EREEQQLHRQERDRKFLEEEPQLRRQE 1656
E Q R QE + Q R++ + R+ E L Q ER +Q+L Q+ + LE++ + +
Sbjct: 1622 ARELQERDQEVKSQ-REQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKI 1680
Query: 1657 REQQLR------HDRDRKFREEEQLLQEGEEQQLRRQERDRK--------FREEEQQLRR 1702
E+ L +R R+ + QL+QE E+ + R R++E+++
Sbjct: 1681 LEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVEC 1740
Query: 1703 QERERKFLQE-----EQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRP 1757
Q+ LQE EQQL Q L RK E L + EQE + Q++ ++ E+ +L+
Sbjct: 1741 QQEHIHELQELKDQLEQQL--QGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKE 1798
Query: 1758 EREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQR 1817
+ + QL +R R++E ++E+QQ + QE +R + + L+ E+ + ++R
Sbjct: 1799 QSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQE-ERVKEKADALQGALEQAHMTLKER 1857
Query: 1818 DGKYRWEEEQLQ---------------LEEQEQRLRQERDRQYRA--------EEQFATQ 1854
G+ + +EQ + LEE LR E Q +A EQ
Sbjct: 1858 HGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEH 1917
Query: 1855 EKSRREEQELWQEEEQ--KRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRL 1912
E R Q+ W + + K R + LR E + +EE + ++ GK H L
Sbjct: 1918 EVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAAL 1977
Score = 229 bits (584), Expect = 2e-59
Identities = 389/1881 (20%), Positives = 763/1881 (40%), Gaps = 379/1881 (20%)
Query: 374 EQQLRREQQLRREQQLRREQQLRREQQLRREQQ-LRREQQLRREQQLRREQQLRREQEE- 431
E+Q+ QQ E Q ++L+ Q+ ++ Q L R+ Q + Q Q+L + E
Sbjct: 21 EEQVLALQQQMAENQAASWRKLKNSQEAQQRQATLVRKLQAKVLQYRSWCQELEKRLEAT 80
Query: 432 -----ERHEQKHEQERREQRLKREQEERR------------------------------- 455
+R E E E ++ E+E++R
Sbjct: 81 GGPIPQRWENVEEPNLDELLVRLEEEQQRCESLAEVNTQLRLHMEKADVVNKALREDVEK 140
Query: 456 ---DW------LKREEETERHEQERRKQQLKRD---------QEEERRERWLKLEEEERR 497
DW L R+E + EQE K LK + + R +L+++ R
Sbjct: 141 LTVDWSRARDELMRKESQWQMEQEFFKGYLKGEHGRLLSLWREVVTFRRHFLEMKSATDR 200
Query: 498 EQQERREQQLR----------------REQEERREQRLKRQEEEERLQQRLRSEQQLRRE 541
+ E + + +R + +E R+ +E + L L Q+L +E
Sbjct: 201 DLMELKAEHVRLSGSLLTCCLRLTVGAQSREPNGSGRMDGREPAQ-LLLLLAKTQELEKE 259
Query: 542 QEERREQLLKREEEKRLEQERREQRL---------KREQEERRDQLLK------------ 580
ER ++L++ + + LE+ + R+ ++Q E ++++K
Sbjct: 260 AHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETN 319
Query: 581 ----REEERRQQRLKREQEERLEQRLKR------EEVERLEQEERREQRL---------- 620
E E R +E++ L+Q +K EE + + Q E L
Sbjct: 320 HTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQF 379
Query: 621 -----------------KREEPEEERRQQLLKSEEQEERRQQQLRREQQERR--EQRL-K 660
+R + ++ RQQL +E QQQ + ++E + QRL K
Sbjct: 380 DYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQK 439
Query: 661 REEEEERLEQR---LKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQS 717
E + L + L+ E + +E+EL ++ +E+ R++++ + + W+L R+
Sbjct: 440 LTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEV-LEQEAWRL------RRV 492
Query: 718 KVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKS 777
V + + Q +++EQ+E+ E + +E + ++ E + +A E S
Sbjct: 493 NVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESS 552
Query: 778 ERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE 837
+ L +EQ E +Q E + R +L L E
Sbjct: 553 HLEGELLR-----QEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEA 607
Query: 838 EQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQE 897
L + QQL + E+ Q R + EQ R+ + L E KRR L+
Sbjct: 608 LALDKVGLNQQLLQLEEENQSVCSRMEAAEQARN-ALQVDLAEAEKRREALWEKNTHLEA 666
Query: 898 QLRKEQQL----------LQEEEEELQREEREKRRRQE---------QERQYREEEQLQ- 937
QL+K ++ +QEE+EE+Q++ E R +QE + R+EE L
Sbjct: 667 QLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLAR 726
Query: 938 --QEEEQLLRE--------EREKRRRQERERQYR--------KDKKLQQKEEQLLGEEPE 979
QE+E L+RE + +R RQ+ Q + + L + ++Q E
Sbjct: 727 AVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVT 786
Query: 980 KRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ-EWERQYRKKDELQQEEEQLLREER 1038
K + + + + + +E+ Q E + L+ E + R Q E ER + Q E+E E+
Sbjct: 787 KGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQ 846
Query: 1039 EKRRLQERERQYREEEELQQE-EEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE 1097
+K ++ Q RE+ E ++ +Q L + E+ R+++E + R +E QQ E + ++ +
Sbjct: 847 QKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKE--QQTEMEAIQAQ 904
Query: 1098 PEKRRRQERERQCREEEELQQEE----EQLLREEREKRRRQELERQYREEEEVQQEEEQ- 1152
E+ R Q C+ + E ++E E LL+ ++E + + R++ +VQ+ +EQ
Sbjct: 905 REEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQE 964
Query: 1153 ---LLREEPEKRRRQ--ELERQYREE-EELQQEEEQLLREEQEKRRQERERQYR-----E 1201
+L+ + ++ +R+ E RQ+R++ LQ+E LL+++ + ++Q + + + +
Sbjct: 965 TTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDD 1024
Query: 1202 EEELQRQKRKQRYRDEDQRSDLKWQWEPEKE----NAVRDNKVYCKGRENEQFRQLEDSQ 1257
+ L Q+ +++ R+ + + ++ + E EK + + + +E + RQ E S
Sbjct: 1025 SQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSA 1084
Query: 1258 LRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEE 1317
LR QD+Q GEQ+E + E R + +++ E +E + + + E
Sbjct: 1085 LR-----QDMQEAQGEQKELSAQMELLRQEVKEK----EADFLAQEAQLLEELEASHITE 1135
Query: 1318 KQLLREEREEKRRRQETDRKFREEEQLLQ--EREEQPLRRQERDRKFREEELRHQEQGRK 1375
+QL ++ + + + R E L+ E+QP + + + Q+
Sbjct: 1136 QQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGS 1195
Query: 1376 FLEEEQRLR--------------RQERERKFLKEEQQLRCQERE------QQLRQD--RD 1413
E L Q R K L E +L QD +
Sbjct: 1196 VCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKT 1255
Query: 1414 RKFRE----EEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQL 1469
++ R+ + Q+L + D + + + Q+ +R+ + +++ + ++ E +L
Sbjct: 1256 QQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESEL 1315
Query: 1470 LQERE-----EQQLHRQERDRKFLEEEQQL----------------------RRQERDRK 1502
++ E + +L R E R + E++L R Q
Sbjct: 1316 MELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAG 1375
Query: 1503 FREQELRSQEPERKFLEEEQQLHRQQRQR------------KFLQEE------------- 1537
E++LR+ K EE + R++ Q K LQE
Sbjct: 1376 ILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREE 1435
Query: 1538 ---------QQLRRQERGQ------------QRRQDRD---RKFREEEQLRQEREEQQLS 1573
Q+L +Q Q +R Q+ D + +E E+ R E ++
Sbjct: 1436 EVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMA 1495
Query: 1574 RQERDRKFRLEEQKVRRQEQERKFMED--EQQLRRQEGQQQLRQERDRKFREDEQLLQER 1631
QER++K ++ +++R E++R+ + E QL E + Q+ + + + ++ ++ L
Sbjct: 1496 VQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTL 1555
Query: 1632 E------EQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR 1685
E E+ H+ E +K ++E R +R D + R +E Q + L
Sbjct: 1556 ECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLE 1615
Query: 1686 R---------QERDRKFREEEQQLRRQERERKFLQEEQQLRRQEL-----------ERKF 1725
QERD++ + + +Q+ +R+++ L ++ + R QEL +++
Sbjct: 1616 SHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRT 1675
Query: 1726 REEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQ-----------------LRRQE 1768
R+ + L ++ EQ +L +ER R++ + QL ER E+ LR +E
Sbjct: 1676 RQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKE 1735
Query: 1769 RDRKFREE--EQLRQEREEQQLRSQESDRKFREEEQLRQERE------EQQLRPQQRDGK 1820
++ + ++E +L++ +++ + + Q RK E L +RE +QQL+ + G+
Sbjct: 1736 KEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGE 1795
Query: 1821 YRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKL 1880
+ + Q QL+E ++ L Q RD++ A +Q Q + + E + + Q ++ L
Sbjct: 1796 LKEQSLQSQLDEAQRALAQ-RDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTL 1854
Query: 1881 REEHIRRQQKEEQRHRQVGEI 1901
+E H Q +EQ R E+
Sbjct: 1855 KERHGELQDHKEQARRLEEEL 1875
Score = 215 bits (547), Expect = 4e-55
Identities = 378/1743 (21%), Positives = 715/1743 (41%), Gaps = 283/1743 (16%)
Query: 405 QQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEET 464
Q + EQ L +QQ+ Q + + E + Q ++L+ + + R W + E+
Sbjct: 17 QLVLEEQVLALQQQMAENQAASWRKLKNSQEAQQRQATLVRKLQAKVLQYRSWCQELEKR 76
Query: 465 ERHEQERRKQQLKRDQEEERRERWLKLEEEERR-EQQERREQQLRREQEERREQRLKRQE 523
Q+ + +E E ++LEEE++R E QLR E+ +E
Sbjct: 77 LEATGGPIPQRWENVEEPNLDELLVRLEEEQQRCESLAEVNTQLRLHMEKADVVNKALRE 136
Query: 524 EEERL--------QQRLRSEQQLRREQEERREQLLKREEEKRLEQER-----REQRLKRE 570
+ E+L + +R E Q + EQE + LK E + L R R L+ +
Sbjct: 137 DVEKLTVDWSRARDELMRKESQWQMEQEFFK-GYLKGEHGRLLSLWREVVTFRRHFLEMK 195
Query: 571 QEERRDQL-LKREEERRQQRL----------KREQEERLEQRLKREEVERLEQEERREQR 619
RD + LK E R L + +E R+ E +L + Q
Sbjct: 196 SATDRDLMELKAEHVRLSGSLLTCCLRLTVGAQSREPNGSGRMDGREPAQLLLLLAKTQE 255
Query: 620 LKREEPEEERRQQLLKSEEQEERRQQQLR-REQQERREQRLKREEEEERLEQRLKREHE- 677
L++E E + LKS+ E+ + Q R E Q K+ E+ E++ + L+ E
Sbjct: 256 LEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEI 315
Query: 678 EERREQELAEEEQEQARERIKSRIPKWQ------WQLESEAD------------ARQSKV 719
E EL E E +R + ++ Q + E D S +
Sbjct: 316 LETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSI 375
Query: 720 YSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE--EQRRDFTWQWQAEEKS 777
+S+ Q+ + RR +Q ++ A Q+ +Q+ D QW+ E K+
Sbjct: 376 FSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHD---QWEEEGKA 432
Query: 778 ERGR-QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEE 836
R R Q+L+ ER A + + +E+E ++ R E ++L+ LE+
Sbjct: 433 LRQRLQKLTG--------ERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQ 484
Query: 837 EEQLQRRERAQQLQEEEDGLQEDQERRRSQ------EQRRDQKWRWQLEEERKRRRHTLY 890
E RR +LQ + D Q +E ++ + E+ R Q+ LE ++ L
Sbjct: 485 EAWRLRRVNV-ELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELI 543
Query: 891 AKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREK 950
E E +LL++E+ E+ R + +L E L E +
Sbjct: 544 TLREALESSHLEGELLRQEQTEV---------TAALARAEQSIAELSSSENTLKTEVADL 594
Query: 951 RRRQERERQYRKDKKLQQ--KEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREER 1008
R + + L + +QLL E E + R E E + Q+ E
Sbjct: 595 RAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSR----MEAAEQARNALQVDLAEA 650
Query: 1009 EKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQE-EEQLLGEE 1067
EKRR WE+ + +LQ+ EE + + R +QE E+EE+Q++ E +E
Sbjct: 651 EKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQE------EKEEIQKKLSESRHQQE 704
Query: 1068 RETRRRQELERQYRKEEEL----QQEEEQLLREEPEKRRRQERERQCREE--EELQ--QE 1119
T + ++L ++ +++EE+ QE+E L+RE+ R + + R++ E+LQ
Sbjct: 705 AATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSS 764
Query: 1120 EEQLLREEREKRRRQ---------ELERQYR---EEEEVQQEEEQLLREEPEKRRRQ-EL 1166
++LL + ++Q +LE Q + + +EV Q E + L+ E + R Q E
Sbjct: 765 AKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQ 824
Query: 1167 ERQYREEEELQQEEEQLLREEQEKRRQERE-RQYREE----------------EELQRQK 1209
ER + Q E+E EQ+K E+E Q RE+ E L+R+K
Sbjct: 825 ERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREK 884
Query: 1210 RKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGR-ENEQFR-QLEDSQLRDRQSQQDL 1267
+ R ++Q+++++ +E + C+ + E E+ R L ++ L+ ++ D
Sbjct: 885 MELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADA 944
Query: 1268 QHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKS----QEEKQLLRE 1323
L E+ +D + ++ + Q+ + Q + E KEA R+ R QEE L +
Sbjct: 945 SQQL-ERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQ 1003
Query: 1324 EREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRL 1383
++ + +++ E D K QL+ + + Q L QE K RE QE R +++E
Sbjct: 1004 DKMDLQKQVE-DLK----SQLVAQDDSQRLVEQEVQEKLRET----QEYNR--IQKELER 1052
Query: 1384 RRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQE 1443
+ +++EQ+L + +RQ R++ Q+ ++++ + E + +E
Sbjct: 1053 EKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKE 1112
Query: 1444 RERKFLEEEQQLRQERHRKFREEEQL-----LQEREEQQLHRQERDRKFLEEEQQLRRQE 1498
+E FL +E QL +E E+QL QE + QL + R + E +Q
Sbjct: 1113 KEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQP 1172
Query: 1499 RDRKFREQELRS------------------------QEPERKFLEEEQQLHRQQRQR--- 1531
++ + +L S P LE +Q R +R
Sbjct: 1173 GNQAQAQAQLASLYSALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPL 1232
Query: 1532 -----------------KFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR 1574
+ L + QQ R R Q ++ + E E+ + E Q L R
Sbjct: 1233 LTALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQR 1292
Query: 1575 QERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQ 1634
Q + + + ++ E + ME + + + + + + + + + + +LLQ +E
Sbjct: 1293 QLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKEN 1352
Query: 1635 QLHRQERDRKFLEE-----------EPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQ 1683
+ E + + E E LR +L+++ RE Q LQE E +
Sbjct: 1353 LTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELK 1412
Query: 1684 LRR----QER----DRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQET 1735
+ + QE + E E+++ + + L++++++++ LE + ++ QE
Sbjct: 1413 VAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEV 1472
Query: 1736 --EQEQLRRQERYRKILEEEQLRPEREEQ-------QLRRQERDRKFR----EEEQLRQE 1782
+QEQ++ E+ R +LE + + EQ Q+R E+DR+ + E + L E
Sbjct: 1473 DLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELE 1532
Query: 1783 REEQQLRSQ----------------------ESDRKFREEEQLRQEREEQQ--------- 1811
+++Q + SQ E+ K +++L +E E Q+
Sbjct: 1533 KKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTH 1592
Query: 1812 --LRPQQRDGKYRWEEEQL------------QLEEQEQRLRQERDR--QYRAEEQFATQE 1855
L ++R + + + Q+ +L+E++Q ++ +R++ + + +++ TQ+
Sbjct: 1593 LTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQD 1652
Query: 1856 KSRREEQELWQEEE---QKRRQERERKLREE-------HIRRQQKEEQRHRQVGEIKSQE 1905
RR+++ + Q+E + ++ R+ K+ EE +R + +E RQ+ + +++E
Sbjct: 1653 LERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEE 1712
Query: 1906 GKG 1908
GKG
Sbjct: 1713 GKG 1715
Score = 189 bits (480), Expect = 2e-47
Identities = 247/1136 (21%), Positives = 496/1136 (43%), Gaps = 93/1136 (8%)
Query: 90 GQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELA 149
G+ L+ E + SL R+ E QR +R+L + + + + + +
Sbjct: 1306 GKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVV 1365
Query: 150 EGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQ 209
E Q+ LE+ R R + + ERE +A +EQ E +
Sbjct: 1366 EARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQ---------GELKVAQG 1416
Query: 210 LRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR 269
+E L L + E++++ + ++ + E+++E +K E L + +R +
Sbjct: 1417 KALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAAL------ELLSLDLKKRNQ 1470
Query: 270 ELQEEEEQLRKLE--RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER 327
E+ ++EQ+++LE R L ++++Q+L +++ R+ E++R Q+ Q
Sbjct: 1471 EVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLE 1530
Query: 328 REQQEERREQQLRREQEERRE----QQLRREQEEERR----EQQLRREQEEERREQQLRR 379
E++++ E Q + Q+ +++ + L E EE +Q+L +E E +R Q++
Sbjct: 1531 LEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVAL 1590
Query: 380 EQQLRREQQLRREQQLRREQ--QLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQK 437
++ +E Q + Q L + + R+Q+++ +++ E + ++
Sbjct: 1591 THLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLT 1650
Query: 438 HEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERR 497
+ ERR+Q L Q+ER L+ + + E +Q+K E RE + + + R
Sbjct: 1651 QDLERRDQELML-QKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQER 1709
Query: 498 EQQERREQQLRREQEERREQRLKRQEEE-ERLQQRLRSEQQLRREQEERREQLLKREEEK 556
++ + + +R E + L+ +E+E E Q+ + Q+L+ + E++ + L ++ E
Sbjct: 1710 AEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGET 1769
Query: 557 RLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR-EEVERLEQEER 615
L +REQ + Q++ ++ + + E ++Q L+ + +E +R +E+E L+QE++
Sbjct: 1770 SLLLSQREQEIVVLQQQLQE--AREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQ 1827
Query: 616 REQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKRE 675
+ Q +EE +E+ L + EQ ++ E Q+ +EQ +R EEE +E R +
Sbjct: 1828 QAQ--GQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQ-ARRLEEELAVEGRRVQA 1884
Query: 676 HEE-------ERREQE---LAEEEQ--EQARE-RIKSRIPKWQWQLESEADARQSKVYSR 722
EE E REQE LA ++Q EQA+E +++R + W L+++A ++
Sbjct: 1885 LEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSW-LQAQAVLKERDQELE 1943
Query: 723 PRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQ 782
+ E Q R ++E R R E+ + + A Q +E+ E + +
Sbjct: 1944 ALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQA 2003
Query: 783 RLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQR 842
L A Q E LR +E + ++Q L +E+ +Q ++ +R++EL+ +E EQL
Sbjct: 2004 SLDACQAHSRQLEEALRIQEGEIQDQD-LRYQEDVQQLQQALAQRDEELRHQQEREQLLE 2062
Query: 843 RERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKE 902
+ AQ++QE QE++ ++R +++ R L + +R+
Sbjct: 2063 KSLAQRVQE-----NMIQEKQNLGQEREEEEIR------------------GLHQSVREL 2099
Query: 903 QQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRK 962
Q L ++E+E+ E RE ++R E + EE+ L + E R ++E ER
Sbjct: 2100 QLTLAQKEQEI-LELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERL--- 2155
Query: 963 DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK 1022
Q + E R + REK L Q + + + Q +
Sbjct: 2156 ---------QAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDS 2206
Query: 1023 KDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK 1082
+ + Q+E +L R EK RL E + E+ LGE + ++
Sbjct: 2207 EQQRLQDELELTRRALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQ 2266
Query: 1083 --EEELQQEEEQLLREEPEKRRRQERERQCREE-EELQQEEEQLLREEREKRRRQELERQ 1139
+ L+ ++ + R E ++ R Q Q R E++++E +L RE + LE
Sbjct: 2267 SWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVERERRKLKREAMRAAQAGSLEIS 2326
Query: 1140 YREEEEVQQEEEQLLREEPEK----RRRQELERQYREEEELQQEEEQLLREEQEKR 1191
Q++ + + K +++ + Q + E +Q+++ + R Q R
Sbjct: 2327 KATASSPTQQDGRGQKNSDAKCVAELQKEVVLLQAQLTLERKQKQDYITRSAQTSR 2382
Score = 171 bits (432), Expect = 8e-42
Identities = 297/1369 (21%), Positives = 571/1369 (41%), Gaps = 152/1369 (11%)
Query: 602 LKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKR 661
+K + ++ + +E+ + + E + ++L S+E ++R+ +R+ Q + + R
Sbjct: 11 MKPQSLQLVLEEQVLALQQQMAENQAASWRKLKNSQEAQQRQATLVRKLQAKVLQYRSWC 70
Query: 662 EEEEERLE-------QRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADA 714
+E E+RLE QR + E E + EE++Q E + + + +E +AD
Sbjct: 71 QELEKRLEATGGPIPQRWENVEEPNLDELLVRLEEEQQRCESLAEVNTQLRLHME-KADV 129
Query: 715 RQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFT-WQWQA 773
+ K R E R+ E QWQ E+ + + E R + W+
Sbjct: 130 VNKALREDVEKLTVDWSRARDELMRK----ESQWQMEQEFFKGYLKGEHGRLLSLWREVV 185
Query: 774 EEKSERGRQRLSARPPLREQRERQLRAEERQ----QREQRFLPEEEEKEQRRRQRREREK 829
+ + + L E + +R R E R RE +
Sbjct: 186 TFRRHFLEMKSATDRDLMELKAEHVRLSGSLLTCCLRLTVGAQSREPNGSGRMDGREPAQ 245
Query: 830 ELQFLEEEEQLQR--RERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRH 887
L L + ++L++ ER+Q+L + L+ + +++ Q R + L + +K+
Sbjct: 246 LLLLLAKTQELEKEAHERSQELIQ----LKSQGDLEKAELQDRVTELSALLTQSQKQNED 301
Query: 888 TLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQER-----QYREEEQLQQEEEQ 942
Y K + + LR+ ++L+ EL E R ++E+ ++ Q+ EE
Sbjct: 302 --YEK--MIKALRETVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGD 357
Query: 943 LLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQ 1002
+ + E + Q ++ L RR++ + R++ QE
Sbjct: 358 NIAQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVN 417
Query: 1003 LLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQ 1062
LL+++ + +WE EE + LR+ +K E + L +
Sbjct: 418 LLQQQHD-----QWE-----------EEGKALRQRLQKLT--------GERDTLAGQTVD 453
Query: 1063 LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQ 1122
L GE + +EL ++ R EEL+Q+ E +L +E + RR E Q + + Q+EEQ
Sbjct: 454 LQGEVDSLSKERELLQKAR--EELRQQLE-VLEQEAWRLRRVNVELQLQGDSAQGQKEEQ 510
Query: 1123 LLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQ 1182
++EL RE E +Q E L+ E ++ RE E E +
Sbjct: 511 ----------QEELHLAVRERERLQ---EMLMGLEAKQSESLSELITLREALESSHLEGE 557
Query: 1183 LLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYC 1242
LLR+EQ + R + EL + + D R+ K +A+ +
Sbjct: 558 LLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRA------AAVKLSALNEALALD 611
Query: 1243 KGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLERE 1302
K N+Q QLE+ + + Q E E+RR +++ E QL++
Sbjct: 612 KVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKA 671
Query: 1303 EQKEAKRRD--RKSQEEKQLLREEREEKRRRQET-------------------DRKFREE 1341
E+ A+ + R QEEK+ ++++ E R +QE R +E+
Sbjct: 672 EEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEK 731
Query: 1342 EQLLQEREEQPLRRQ--ERDRKFREEELRHQEQGRKFLEE---EQRLRRQERERKFLKEE 1396
E L++E+ +R Q ERDR+ E+L+ ++ LE E + + E + E
Sbjct: 732 EALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLE 791
Query: 1397 QQLRCQEREQQLRQDRDRKFREE---EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQ 1453
Q++ + +++ Q R + E E+ + QERD R Q+ + E+E K E+Q
Sbjct: 792 VQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAAR----QLAQAEQEGKTALEQQ 847
Query: 1454 QLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEP 1513
+ E +E QL ++ E+++ Q+ K LE ER++ E L+ Q+
Sbjct: 848 KAAHE-----KEVNQLREKWEKERSWHQQELAKALES------LEREKMELEMRLKEQQT 896
Query: 1514 ERKFLEEEQQLHRQQRQRKFLQ-----EEQQLRRQERGQQRRQDRDRKFREEEQLRQERE 1568
E + ++ +++ R Q + Q E++++ E Q +++ ++ E+LRQ+ +
Sbjct: 897 EMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMK 956
Query: 1569 EQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLL 1628
Q+L QE + + Q+ +R+ +E + QE L Q+ + D Q
Sbjct: 957 VQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQD-----KMDLQKQ 1011
Query: 1629 QEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQL---LQEGEEQQLR 1685
E + QL Q+ ++ +E+E Q + +E ++ R ++ + RE+ L L E E++ L
Sbjct: 1012 VEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELE-REKASLTLSLMEKEQRLLV 1070
Query: 1686 RQERDRKFREE----EQQLRRQERERKFLQEEQQLRRQELERK----FREEEQLRQETEQ 1737
QE D ++E Q ++ + E+K L + +L RQE++ K +E QL +E E
Sbjct: 1071 LQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEA 1130
Query: 1738 EQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKF 1797
+ Q+ R L ++ + + + +LR E + EQ Q + Q ++Q +
Sbjct: 1131 SHITEQQ-LRASLWAQEAKAAQLQLRLRSTESQLEALAAEQ--QPGNQAQAQAQLASLYS 1187
Query: 1798 REEEQLRQEREEQQLRPQ-QRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEK 1856
++ L E RP+ G L+ ++ R +R A A
Sbjct: 1188 ALQQALGSVCES---RPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASA 1244
Query: 1857 SRREEQELWQEEEQKR-RQERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904
+ Q+LW+ ++ + +++ +KL E + ++ Q H ++ +++ Q
Sbjct: 1245 LHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQ 1293
Score = 160 bits (406), Expect = 9e-39
Identities = 210/901 (23%), Positives = 392/901 (43%), Gaps = 101/901 (11%)
Query: 58 LELLDLD---SNGRVDFNEFLLFIFKVAQACYYALGQATGLDEEKRARCDGKESLLQDRR 114
LELL LD N VD + + + ++ L A + E ++ +E + + +
Sbjct: 1458 LELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMA--VQEREQKLTVQREQIRELEK 1515
Query: 115 QEEDQRR--------FEPRDRQLEEEPGQRRRQKRQEQERE-----LAEGEEQSEKQERL 161
E QR E +D+ +E + GQ + K+Q E L E + E Q++L
Sbjct: 1516 DRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKL 1575
Query: 162 EQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRK 221
+ +R+ + + EER ++E Q QS + H+ E + REL E ++
Sbjct: 1576 IKELEGQRETQRVALTHLTLDLEER-SQELQAQSSQIHDLES---HSTVLARELQERDQE 1631
Query: 222 GREEKQQ-QRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRK 280
+ +++Q + +RQ ++ E+ R +E +L+KE ++ E++ RQ ++ EE+ + K
Sbjct: 1632 VKSQREQIEELQRQKEHLTQDLER--RDQELMLQKERIQVLEDQRTRQTKILEEDLEQIK 1689
Query: 281 LERQE----------LRRERQEE-----EQQQQRLRREQQLRRKQEEERREQQEERREQQ 325
L +E L +ER EE + Q+ L + + R +E+E QQE E Q
Sbjct: 1690 LSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQ 1749
Query: 326 ERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEE-ERREQQLRREQQLR 384
E ++Q E++ Q L R+ E +REQE +QQL+ +E+ E +EQ L+ +
Sbjct: 1750 ELKDQLEQQL-QGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEA 1808
Query: 385 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE 444
+ +R+Q+L QQ +++ Q + E+ + L+ + +ERH + + + +
Sbjct: 1809 QRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQA 1868
Query: 445 QRLKREQEERRDWLKREEE------TERHEQERRKQQLKRDQEEERRER----------W 488
+RL+ E ++ EE E EQE+ L++ E+ +E W
Sbjct: 1869 RRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSW 1928
Query: 489 LK----LEEEERREQQERREQQLRREQEERREQRLKRQEEE--------ERLQQRLRSEQ 536
L+ L+E ++ + R E Q R QEE R + +E + +Q L +
Sbjct: 1929 LQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQA 1988
Query: 537 QLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEE---------RRQ 587
+L R E L + + + E+ L+ ++ E +DQ L+ +E+ +R
Sbjct: 1989 ELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRD 2048
Query: 588 QRLKREQEERLEQRLKREEVERLEQEERRE-QRLKREEPEEERR------QQLLKSEEQE 640
+ L+ +QE EQ L++ +R+++ +E Q L +E EEE R ++L + Q+
Sbjct: 2049 EELRHQQER--EQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQK 2106
Query: 641 ERRQQQLRREQQERREQRLKREEEEERL-EQRLKREHEEERREQELAEEEQEQARERIKS 699
E+ +LR QQ + L + + EQ LK + E R ++EL E + A + ++
Sbjct: 2107 EQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQREL--ERLQAALRQTEA 2164
Query: 700 RIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQ 759
R +W+ E D S ++ Q + R+SE Q ++E ++
Sbjct: 2165 REIEWR---EKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRA 2221
Query: 760 EEEQRRDFTWQWQAEEKSERGRQRLS-------ARPPLREQRERQLRAEERQQREQRFLP 812
E++R E RG Q + P + E+Q + + +Q
Sbjct: 2222 LEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVAR 2281
Query: 813 EEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872
E ++ + +R + L+ +E E + +RE + Q + + +Q+ R Q
Sbjct: 2282 LEIDRSRLQRHNVQLRSTLEQVERERRKLKREAMRAAQAGSLEISKATASSPTQQDGRGQ 2341
Query: 873 K 873
K
Sbjct: 2342 K 2342
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 295 bits (754), Expect = 4e-79
Identities = 194/665 (29%), Positives = 386/665 (58%), Gaps = 69/665 (10%)
Query: 528 LQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR---EQRLKREQEERRDQLLKREEE 584
LQ+ L + ++ + E+L K + LE R + LK++ E +++L E E
Sbjct: 143 LQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESE 202
Query: 585 RRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
+ + +L ++ +R +R K + +++ +E+ ++EE E+ +++ K EE+ R++
Sbjct: 203 KSEIQLNVKELKRKLERAKFL-LPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQE 261
Query: 645 QQLRREQQERREQRLKREEEEERLEQRLK--REHEEERREQELAEEEQEQARERIKSRIP 702
++LR ++ + REQ K +E+RL ++ K RE E+E REQ+ E++EQ +E+ +
Sbjct: 262 ERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEK--- 318
Query: 703 KWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEE 762
W+ E + ++ K++ + + Q ++ ++E++ R + E W+++ER +++EE
Sbjct: 319 --MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL---REKEE 373
Query: 763 QRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRR 822
+ R+ W+ EEK + + +RE RE+++R EE REQ EE+ ++Q
Sbjct: 374 RMREQEKMWEQEEKMQEEER-------IRE-REKKMREEEETMREQ----EEKMQKQEEN 421
Query: 823 QRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEER 882
+ EKE Q EQ ++ +++QE+E+ + E +E+ R QE+ W E++
Sbjct: 422 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM------WGQEKKM 475
Query: 883 KRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQ 942
R QE++R+++ + E+EE+++ ++E++ ++ER + ++E+L+++EE+
Sbjct: 476 WR-----------QEKMREQEDQMWEQEEKMR--DQEQKMWDQEERMWEQDERLREKEER 522
Query: 943 LLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEP---EKRRRQEREKKYREEEELQQE 999
+ RE+++ ++E + R++KK Q++E++ +E E+ R +EREKK REEEE+ +E
Sbjct: 523 M----REQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 578
Query: 1000 EEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQE 1059
+E+ ++E+ EK R QE E E+E+ ++E+ EK QE + +EEE+ QE
Sbjct: 579 QEEKMQEQEEKMREQE---------EKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQE 629
Query: 1060 EEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE 1119
+E+++ E+ E + QE E+ + +EE+++++EE+ +RE+ EK Q +E + RE+EE Q
Sbjct: 630 QEEMMWEQEEKMQEQE-EKMWEQEEKMREQEEK-MREQEEK--MQGQEEKMREQEEKMQG 685
Query: 1120 EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE--EEELQ 1177
+E+ +RE+ EK R QE E+ + +EE++ +EE++ +E E R ++E R +E +E L
Sbjct: 686 QEEKMREQEEKMRGQE-EKMWGQEEKMWGQEEKMWGQE-EMREKEERIRDQKEKMQERLP 743
Query: 1178 QEEEQ 1182
+ EE+
Sbjct: 744 EHEER 748
Score = 293 bits (749), Expect = 1e-78
Identities = 211/750 (28%), Positives = 424/750 (56%), Gaps = 88/750 (11%)
Query: 812 PEEEEKEQRRRQRREREKELQFLEEEEQL---QRRERAQQLQEEEDGLQEDQERRRSQEQ 868
PE+E+K + Q R +E++ + ++ Q+ E L +D ++ ++ + +
Sbjct: 69 PEDEKKASHQHQEALR-REIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESK 127
Query: 869 ----RRDQKWRWQLEEERKRRRHTLYAKPALQ--EQLRKEQQLLQEE--EEELQREEREK 920
R W + E +R + + K A + E+L KE+ L E + EE +K
Sbjct: 128 DLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKK 187
Query: 921 RRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEK 980
+ + QE+ E E+ ++ +E +R+ ER + + +E++ +E E
Sbjct: 188 KNAELQEKLRLAES----EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEEL 243
Query: 981 RRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREK 1040
R E+EKK R++EE +E+ LRE+ K R QE ++++++E++L +E+E
Sbjct: 244 R---EQEKKIRKQEEKMWRQEERLREQEGKMREQE--------EKMRRQEKRLREQEKE- 291
Query: 1041 RRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEK 1100
L+E+E++ RE+++L+++EEQ+ +E+E + ++ E+ +EE++ ++EE+L +E +
Sbjct: 292 --LREQEKELREQKKLREQEEQM--QEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQM 347
Query: 1101 RRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEK 1160
R E+E++ R++EE E+++ LRE+ E+ R QE + E+EE QEEE++ E EK
Sbjct: 348 R---EQEQKMRDQEERMWEQDERLREKEERMREQE---KMWEQEEKMQEEERI--REREK 399
Query: 1161 RRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQR 1220
+ R+E E +EE++Q++EE + EQE++ +++R ++E+L Q++ Q ++
Sbjct: 400 KMREEEETMREQEEKMQKQEENMW--EQEEKEWQQQRLPEQKEKLWEQEKMQ------EQ 451
Query: 1221 SDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDRE 1280
+ W E+E +RD + G+E + +RQ ++R+++ Q + EQ+E+ R+
Sbjct: 452 EEKIW----EQEEKIRDQEEMW-GQEKKMWRQ---EKMREQEDQ------MWEQEEKMRD 497
Query: 1281 QERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE 1340
QE++ W Q +R + ++E+L +E++ +++ QEEK REEK+ +++ + + +
Sbjct: 498 QEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKM-----REEKKTQEQEKKTWDQ 552
Query: 1341 EEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLR 1400
EE++ REE+ +R ER++K REEE +EQ K E+E+++R QE + EQ+ +
Sbjct: 553 EEKM---REEERMR--EREKKMREEEEMMREQEEKMQEQEEKMREQEEK----MWEQEEK 603
Query: 1401 CQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERH 1460
QE+E+++ + ++ + +EE+ +++ + + +EE + QE+E K E+E+++R E+
Sbjct: 604 MQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEE---KMQEQEEKMWEQEEKMR-EQE 659
Query: 1461 RKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEE 1520
K RE+E+ +Q +EE+ +E++ K +E+++R QE K R QE + E K +
Sbjct: 660 EKMREQEEKMQGQEEKM---REQEEKMQGQEEKMREQE--EKMRGQEEKMWGQEEKMWGQ 714
Query: 1521 EQQLHRQQRQRKFLQEEQQLRRQERGQQRR 1550
E+++ Q+ R ++E+++R Q+ Q R
Sbjct: 715 EEKMWGQEEMR---EKEERIRDQKEKMQER 741
Score = 286 bits (732), Expect = 1e-76
Identities = 180/628 (28%), Positives = 376/628 (59%), Gaps = 94/628 (14%)
Query: 792 EQRERQLRAEERQQREQR---FLPEEE----EKEQRRRQRREREKELQFLEEEEQLQRRE 844
E+ E QL +E +++ +R LP+ + ++E R++ RE+E + ++EE++ R+E
Sbjct: 202 EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQE 261
Query: 845 RAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQ 904
++L+E+E ++E +E+ R QE+R ++ + E+E++ R Q++LR++++
Sbjct: 262 --ERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE---------QKKLREQEE 310
Query: 905 LLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDK 964
+QE+EE++ E+E++ R+++E+ +R+EE+L ++E+Q+ E+E++ R + ER + +D+
Sbjct: 311 QMQEQEEKMW--EQEEKMREQEEKMWRQEERLWEQEKQM--REQEQKMRDQEERMWEQDE 366
Query: 965 KLQQKEEQLLGEEP--EKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK 1022
+L++KEE++ +E E+ + + E++ RE E+ +EEE+ +RE+ EK ++QE ++
Sbjct: 367 RLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 426
Query: 1023 KDELQQEEEQLLREEREK----RRLQERERQYREEEELQQEEEQLLGEERETRRRQELER 1078
+ E QQ Q L E++EK ++QE+E + E+EE +++E++ G+E++ R++++
Sbjct: 427 EKEWQQ---QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM-- 481
Query: 1079 QYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELER 1138
R++E+ E+E+ +R++ +K QE ER ++E L+++EE++ RE+++ + E
Sbjct: 482 --REQEDQMWEQEEKMRDQEQKMWDQE-ERMWEQDERLREKEERM----REQKKMWQQEE 534
Query: 1139 QYREEEEVQQEEEQLLREEP---EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
+ REE++ Q++E++ +E E+ R +E E++ REEEE+ +E+E+ ++E++EK R++
Sbjct: 535 KMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE 594
Query: 1196 ERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED 1255
E+ + +EE++Q Q+ K ++E WE E+E+
Sbjct: 595 EKMWEQEEKMQEQEEKMWEQEEK-------MWEQEEED---------------------- 625
Query: 1256 SQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQ 1315
Q+ + ++ EQ+E+ +EQE + W+Q ++ +EE++ +E+K + Q
Sbjct: 626 -------KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK------MQGQ 672
Query: 1316 EEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRK 1375
EEK RE++ + Q + K RE+E+ ++ +EE+ + QE +EE++ QE+ R
Sbjct: 673 EEKM-----REQEEKMQGQEEKMREQEEKMRGQEEK-MWGQEEKMWGQEEKMWGQEEMR- 725
Query: 1376 FLEEEQRLRRQERERKFLKEEQQLRCQE 1403
E+E+R+R Q+ + + E + RC E
Sbjct: 726 --EKEERIRDQKEKMQERLPEHEERCSE 751
Score = 286 bits (731), Expect = 2e-76
Identities = 193/644 (29%), Positives = 378/644 (58%), Gaps = 61/644 (9%)
Query: 877 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQE-------EEEELQREEREKRRRQEQERQ 929
+L +ER LY E+L+K+ LQE E+ E+Q +E +R+ E+ +
Sbjct: 163 ELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKF 222
Query: 930 YREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKK 989
+ Q +E++ R+E E R E+E++ RK ++ ++E+ L E+ K R QE EK
Sbjct: 223 LLPQVQTNTLQEEMWRQEEELR---EQEKKIRKQEEKMWRQEERLREQEGKMREQE-EKM 278
Query: 990 YREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQ 1049
R+E+ L+++E++L +E+E R +++ Q ++++Q++EE++ E+ EK R QE E+
Sbjct: 279 RRQEKRLREQEKELREQEKELREQKKLREQ---EEQMQEQEEKMW-EQEEKMREQE-EKM 333
Query: 1050 YREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQ 1109
+R+EE L ++E+Q+ +E E++ R +EE E+++ LRE+ E+ R QE+
Sbjct: 334 WRQEERLWEQEKQM----------REQEQKMRDQEERMWEQDERLREKEERMREQEK--- 380
Query: 1110 CREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQ 1169
E+EE QEEE++ EREK+ R+E E +EE++Q++EE + +E ++ ++Q L Q
Sbjct: 381 MWEQEEKMQEEERI--REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 438
Query: 1170 YREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEP 1229
+E+L ++E+ +EQE++ E+E + R++EE+ Q++K +R E R WE
Sbjct: 439 ---KEKLWEQEKM---QEQEEKIWEQEEKIRDQEEMWGQEKKM-WRQEKMREQEDQMWEQ 491
Query: 1230 EKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQR 1289
E++ ++ K++ + E+ +D +LR+++ + Q + +Q+E+ RE+++ + Q++
Sbjct: 492 EEKMRDQEQKMW----DQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEK 547
Query: 1290 DRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQERE 1349
EE+ E E +E R++K +EE++++RE+ E + QE + K RE+E+ + E+E
Sbjct: 548 KTWDQEEKMREEERMRE---REKKMREEEEMMREQEE---KMQEQEEKMREQEEKMWEQE 601
Query: 1350 EQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLR 1409
E+ ++ QE +EE++ QE+ K E+E+ + QE + +EQ+ + E+E+++R
Sbjct: 602 EK-MQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEK----MQEQEEKMWEQEEKMR 656
Query: 1410 QDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQL 1469
+++ K RE+E+++ QE K RE+E+++ Q +E K E+E+++R + + + +EE++
Sbjct: 657 -EQEEKMREQEEKMQGQE--EKMREQEEKM--QGQEEKMREQEEKMRGQEEKMWGQEEKM 711
Query: 1470 LQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEP 1513
+ E+ + R+++ +Q+ + QER E E R EP
Sbjct: 712 WGQEEKMWGQEEMREKEERIRDQKEKMQER---LPEHEERCSEP 752
Score = 285 bits (730), Expect = 2e-76
Identities = 198/652 (30%), Positives = 376/652 (57%), Gaps = 91/652 (13%)
Query: 646 QLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQ 705
+L R E + K E +E+L R E E+ E +L +E ++ ER K +P+ Q
Sbjct: 174 ELYRNTITNEELKKKNAELQEKL-----RLAESEKSEIQLNVKELKRKLERAKFLLPQVQ 228
Query: 706 WQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRR 765
+ Q +++ +QE + R QE K+ R++ E W++EER Q+ + ++
Sbjct: 229 ------TNTLQEEMW----RQEEELREQE---KKIRKQEEKMWRQEERLREQEGKMREQ- 274
Query: 766 DFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRR 825
EEK R +RL REQ E++LR +E++ REQ+ L E+EE+ Q
Sbjct: 275 --------EEKMRRQEKRL------REQ-EKELREQEKELREQKKLREQEEQMQ------ 313
Query: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQR-RDQKWRWQLEEERKR 884
E+E + E+EE++ RE+ +++ +E+ L E +++ R QEQ+ RDQ+ R ++ER R
Sbjct: 314 --EQEEKMWEQEEKM--REQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLR 369
Query: 885 RRHTLYAKPALQEQLRKEQQLLQEEEEELQREER----EKRRRQEQERQYREEEQLQQEE 940
+ E+ +EQ+ + E+EE++Q EER EK+ R+E+E +EE++Q++E
Sbjct: 370 EK----------EERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE 419
Query: 941 EQLLREEREKRRRQERERQYRK--DKKLQQKEEQLLGEEPEKRRRQE----------REK 988
E + +E ++ ++Q Q K +++ Q++E+ + E+ EK R QE R++
Sbjct: 420 ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE 479
Query: 989 KYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERER 1048
K RE+E+ E+E+ +R++ +K QE ER + + + L+++EE++ RE++++ ++E
Sbjct: 480 KMREQEDQMWEQEEKMRDQEQKMWDQE-ERMWEQDERLREKEERM----REQKKMWQQEE 534
Query: 1049 QYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERER 1108
+ REE++ Q++E++ +E + R E + R+ E+ +EEE+++RE+ EK QE+E
Sbjct: 535 KMREEKKTQEQEKKTWDQEEKMRE----EERMREREKKMREEEEMMREQEEKM--QEQEE 588
Query: 1109 QCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELER 1168
+ RE+EE E+E+ ++E+ EK QE + +EEE+ QE+E+++ E+ EK + QE E+
Sbjct: 589 KMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQE-EK 647
Query: 1169 QYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWE 1228
+ +EE+++++EE+ +RE++EK + + E+ +EE++Q Q+ K R ++E R + W
Sbjct: 648 MWEQEEKMREQEEK-MREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWG 706
Query: 1229 PEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDRE 1280
E++ ++ K++ G+E ++ + + R R ++ +Q L E +ER E
Sbjct: 707 QEEKMWGQEEKMW--GQE-----EMREKEERIRDQKEKMQERLPEHEERCSE 751
Score = 276 bits (706), Expect = 1e-73
Identities = 195/657 (29%), Positives = 373/657 (56%), Gaps = 82/657 (12%)
Query: 987 EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
+K R EEL +E + L E R + +KK+ QE+ +L E+ + +L +
Sbjct: 155 KKADRYIEELTKERDAL---SLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVK 211
Query: 1047 ERQYREEEE---LQQEEEQLLGEE--RETRRRQELERQYRKEEELQQEEEQLLREEPEKR 1101
E + + E L Q + L EE R+ +E E++ RK+EE +E+ LRE+ K
Sbjct: 212 ELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKM 271
Query: 1102 RRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKR 1161
R QE E+ R+E+ L+++E++L +E+E R +++L RE+EE QE+E+ + E+ EK
Sbjct: 272 REQE-EKMRRQEKRLREQEKELREQEKELREQKKL----REQEEQMQEQEEKMWEQEEKM 326
Query: 1162 RRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRS 1221
R QE E+ +R+EE L EQEK+ +E+E++ R++EE ++ ++ E++
Sbjct: 327 REQE-EKMWRQEERLW---------EQEKQMREQEQKMRDQEERMWEQDERLREKEERMR 376
Query: 1222 DLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQ 1281
+ + WE E+ K +E E+ R+ E + ++ ++ + + +Q+E EQ
Sbjct: 377 EQEKMWEQEE-----------KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 425
Query: 1282 ERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREE----REEKRRRQETDRK 1337
E + WQQ + PE+++ E++K ++ ++ ++E+++ +E +E+K RQE K
Sbjct: 426 EEKEWQQ--QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE---K 480
Query: 1338 FREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQ 1397
RE+E + E+EE + +++++K ++E R EQ + E+E+R+R Q +K ++E+
Sbjct: 481 MREQEDQMWEQEE---KMRDQEQKMWDQEERMWEQDERLREKEERMREQ---KKMWQQEE 534
Query: 1398 QLRCQEREQQLRQ---DRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQ 1454
++R +++ Q+ + D++ K REEE+ +ER++K REEE+ +R QE +
Sbjct: 535 KMREEKKTQEQEKKTWDQEEKMREEERM---REREKKMREEEEMMREQEEK--------- 582
Query: 1455 LRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPE 1514
QE+ K RE+E+ + E+EE+ QE++ K E+E+++ QE + K +EQE E E
Sbjct: 583 -MQEQEEKMREQEEKMWEQEEKM---QEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQE 638
Query: 1515 RKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR 1574
K E+E+++ Q + K ++E+++R QE ++ Q ++ K RE+E+ Q +EE+
Sbjct: 639 EKMQEQEEKMWEQ--EEKMREQEEKMREQE---EKMQGQEEKMREQEEKMQGQEEKM--- 690
Query: 1575 QERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQER 1631
+E++ K R +E+K+ QE++ E+ + GQ+++R E++ + R+ ++ +QER
Sbjct: 691 REQEEKMRGQEEKMWGQEEKMWGQEE-----KMWGQEEMR-EKEERIRDQKEKMQER 741
Score = 275 bits (703), Expect = 3e-73
Identities = 193/640 (30%), Positives = 372/640 (58%), Gaps = 75/640 (11%)
Query: 1286 WQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLL 1345
W ++ + EE ER+ R+ + EE + E +EK R E+++ E QL
Sbjct: 153 WHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKS---EIQLN 209
Query: 1346 QEREEQPLRR------QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL 1399
+ ++ L R Q + +EE R +E+ R E+E+++R+QE K ++E++L
Sbjct: 210 VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR---EQEKKIRKQEE--KMWRQEERL 264
Query: 1400 RCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQE---RERKFLEEEQQLR 1456
R QE K RE+E+++ RQE+ + RE+E+++R QE RE+K L E+++
Sbjct: 265 REQEG----------KMREQEEKMRRQEK--RLREQEKELREQEKELREQKKLREQEEQM 312
Query: 1457 QERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERK 1516
QE+ K E+E+ ++E+EE+ ++ER E+E+Q+R QE+ K R+QE R E + +
Sbjct: 313 QEQEEKMWEQEEKMREQEEKMWRQEER---LWEQEKQMREQEQ--KMRDQEERMWEQDER 367
Query: 1517 FLEEEQQLHRQQR---QRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLS 1573
E+E+++ Q++ Q + +QEE+++R +E+ + ++ + RE+E+ Q++EE
Sbjct: 368 LREKEERMREQEKMWEQEEKMQEEERIREREK---KMREEEETMREQEEKMQKQEENMWE 424
Query: 1574 RQERD-RKFRLEEQKVR------RQEQERKFMEDEQQLRRQEGQ--QQLRQERDRKFRED 1624
++E++ ++ RL EQK + QEQE K E E+++R QE Q+ + R K RE
Sbjct: 425 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 484
Query: 1625 EQLLQEREEQQLHRQER----DRKFLEEEPQLRRQE---REQQLRHDRDRKFREEEQLLQ 1677
E + E+EE+ ++++ + + E++ +LR +E REQ+ ++ K REE++
Sbjct: 485 EDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKT-- 542
Query: 1678 EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ 1737
+EQ+ + +++ K REEE R +ERE+K +EE+ +R QE K +E+E+ +E E+
Sbjct: 543 --QEQEKKTWDQEEKMREEE---RMREREKKMREEEEMMREQE--EKMQEQEEKMREQEE 595
Query: 1738 EQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKF 1797
+ ++E K+ E+E+ E+EE+ ++E D K +E+E++ E+EE+ ++ ++ +
Sbjct: 596 KMWEQEE---KMQEQEEKMWEQEEKMWEQEEED-KMQEQEEMMWEQEEKM--QEQEEKMW 649
Query: 1798 REEEQLRQERE---EQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQ 1854
+EE++R++ E EQ+ + Q ++ K R +EE++Q +E++ R ++E+ R + E+ + +
Sbjct: 650 EQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRG-QEEKMWGQE 708
Query: 1855 EKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQR 1894
EK +E+++W +EE + ++ER R +E+ R + E+R
Sbjct: 709 EKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEER 748
Score = 274 bits (701), Expect = 5e-73
Identities = 228/770 (29%), Positives = 403/770 (52%), Gaps = 108/770 (14%)
Query: 133 PGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQ 192
P ++ Q QE E E Q + R+ + + L+ + ++ E+ E +
Sbjct: 69 PEDEKKASHQHQEALRREIEAQ-DHTIRILTCQKTELETALYYSQDAARKFEDGNLGESK 127
Query: 193 LQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETV 252
+ + H + F E Q + +K ++ +ER +
Sbjct: 128 DLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKER--------DALSLELYRNT 179
Query: 253 LRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRR--ERQEEEQQQQRLRREQQLRRKQ 310
+ EE K + E Q + L E E+ +L +EL+R ER + Q + Q+ +Q
Sbjct: 180 ITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ 239
Query: 311 EEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEE 370
EEE REQ+++ R+Q+E+ +QEER +Q E ++R ++E+ RR+++ REQE+
Sbjct: 240 EEELREQEKKIRKQEEKMWRQEERLREQ---------EGKMREQEEKMRRQEKRLREQEK 290
Query: 371 ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQE 430
E REQ E++LR +++LR +++ +EQ+ E+ +E+++R +++ QE
Sbjct: 291 ELREQ----------EKELREQKKLREQEEQMQEQE---EKMWEQEEKMREQEEKMWRQE 337
Query: 431 EERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK 490
E EQ E++ REQ K +E R W ++E R ++ER ++Q K ++EE K
Sbjct: 338 ERLWEQ--EKQMREQEQKMRDQEERMW--EQDERLREKEERMREQEKMWEQEE------K 387
Query: 491 LEEEER---REQQERREQQLRREQEE---RREQRLKRQEEEERLQQRLRSEQQLRREQEE 544
++EEER RE++ R E++ REQEE ++E+ + QEE+E QQRL +++ EQE+
Sbjct: 388 MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 447
Query: 545 RREQLLK--REEEKRLEQER---REQRLKREQE--ERRDQLLKREEERRQQRLKR-EQEE 596
+EQ K +EEK +QE +E+++ R+++ E+ DQ+ ++EE+ R Q K +QEE
Sbjct: 448 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE 507
Query: 597 RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE 656
R+ E+ ERL ++E R + K+ +EE+ ++ K++EQE++ Q E++ R E
Sbjct: 508 RM-----WEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQ---EEKMREE 559
Query: 657 QRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQ 716
+R++ E++ R E+ + RE EE+ +EQE EQE+ W+ E + ++
Sbjct: 560 ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK-----------MWEQEEKMQEQE 608
Query: 717 SKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEK 776
K++ +QE + QE+E+K + +E E+ W++EE+ Q+QEE+ W+ EEK
Sbjct: 609 EKMW----EQEEKMWEQEEEDKMQEQE-EMMWEQEEK--MQEQEEK-------MWEQEEK 654
Query: 777 SERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEE 836
+REQ E+ EE+ Q ++ + E+EEK Q + ++ RE+E + +
Sbjct: 655 -------------MREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKM-REQEEKMRGQ 700
Query: 837 EEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQ--LEEERKR 884
EE++ +E QEE+ QE E R +E+ RDQK + Q L E +R
Sbjct: 701 EEKMWGQEEKMWGQEEKMWGQE--EMREKEERIRDQKEKMQERLPEHEER 748
Score = 274 bits (700), Expect = 7e-73
Identities = 231/816 (28%), Positives = 416/816 (50%), Gaps = 103/816 (12%)
Query: 208 EQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEK--EWRKRETVLRKEEEKLQEEEP 265
E+ R+ +L E ++K + +Q R +++K ET E E
Sbjct: 15 EKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPETTT---SEGCHSPED 71
Query: 266 QRQRELQEEEEQLRKLERQE--LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERRE 323
+++ Q +E R++E Q+ +R ++ + + L Q RK E+ + ++
Sbjct: 72 EKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAG 131
Query: 324 QQERR-----EQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLR 378
+ E Q ++ +R ++L +E++ E EE +++
Sbjct: 132 RLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAE 191
Query: 379 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKH 438
+++LR + + E QL ++ R+ L R + L + Q Q+ QEEE EQ+
Sbjct: 192 LQEKLRLAESEKSEIQLNVKELKRK---LERAKFLLPQVQTNTLQEEMWRQEEELREQEK 248
Query: 439 EQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERRE 498
+ ++E+++ R++E R+ + + E+ E+ RR+++ R+QE+E RE +E+E RE
Sbjct: 249 KIRKQEEKMWRQEERLRE--QEGKMREQEEKMRRQEKRLREQEKELRE-----QEKELRE 301
Query: 499 QQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRL 558
Q++ REQ+ E+ +EQ K E+EE++ REQEE+ + R+EE+
Sbjct: 302 QKKLREQE-----EQMQEQEEKMWEQEEKM-----------REQEEK----MWRQEERLW 341
Query: 559 EQER--REQRLK-REQEER---RDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612
EQE+ REQ K R+QEER +D+ L+ +EER REQE+ EQ K +E ER+ +
Sbjct: 342 EQEKQMREQEQKMRDQEERMWEQDERLREKEER-----MREQEKMWEQEEKMQEEERIRE 396
Query: 613 EE---RREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERL- 668
E R E+ RE+ E+ ++Q+ E++E+ QQQ EQ+E+ ++ K +E+EE++
Sbjct: 397 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 456
Query: 669 EQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEG 728
EQ K +EE QE QE+ RE+ W+ E + ++ K++ + +
Sbjct: 457 EQEEKIRDQEEMWGQEKKMWRQEKMREQ-----EDQMWEQEEKMRDQEQKMWDQEERMWE 511
Query: 729 QRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP 788
Q R ++E+R R + ++ WQ+EE+ +++ +EQ + TW Q E+ E R R
Sbjct: 512 QDERLREKEERMREQKKM-WQQEEKMREEKKTQEQEKK-TWD-QEEKMREEERMR----- 563
Query: 789 PLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQ 848
+RE+++R EE REQ +E+E++ R ++ + E+E + E+EE++ +E
Sbjct: 564 ----EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 619
Query: 849 LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE 908
QEEED +QE +E QE++ ++ E+E K R
Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR----------------------- 656
Query: 909 EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
E+EE RE+ EK Q QE + RE+E+ Q +E+ +RE+ EK R QE E+ + +++K+
Sbjct: 657 EQEEKMREQEEK--MQGQEEKMREQEEKMQGQEEKMREQEEKMRGQE-EKMWGQEEKMWG 713
Query: 969 KEEQLLGEEPEKRRRQE--REKKYREEEELQQEEEQ 1002
+EE++ G+E E R ++E R++K + +E L + EE+
Sbjct: 714 QEEKMWGQE-EMREKEERIRDQKEKMQERLPEHEER 748
Score = 271 bits (692), Expect = 6e-72
Identities = 197/630 (31%), Positives = 363/630 (57%), Gaps = 82/630 (13%)
Query: 110 LQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGE---------EQSEKQER 160
+++ +E D E + E +++ + QE+ R LAE E E K ER
Sbjct: 161 IEELTKERDALSLELYRNTITNEELKKKNAELQEKLR-LAESEKSEIQLNVKELKRKLER 219
Query: 161 ----LEQRDRQRRDEELWRQRQEWQEREER-RAEEEQLQSCKGHETEEFPDEEQLRRREL 215
L Q EE+WRQ +E +E+E++ R +EE++ + EE+LR +E
Sbjct: 220 AKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKM----------WRQEERLREQE- 268
Query: 216 LELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEE 275
G+ +Q+++ RQ++ + E+EKE R++E LR E++KL+E+E Q Q + ++
Sbjct: 269 ------GKMREQEEKMRRQEKRLR-EQEKELREQEKELR-EQKKLREQEEQMQEQEEKMW 320
Query: 276 EQLRKLERQELRRERQEEE--QQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE 333
EQ K+ QE + RQEE +Q++++R ++Q R QEE EQ E RE++ER +QE+
Sbjct: 321 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK 380
Query: 334 RREQQLRREQEER---REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLR 390
EQ+ + ++EER RE+++R E+E R +++ ++QEE EQ+ + QQ R +Q
Sbjct: 381 MWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE 440
Query: 391 R--EQQLRREQQLR---REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ 445
+ EQ+ +EQ+ + +E+++R ++++ +++ Q+ REQE++ EQ E++ R+Q
Sbjct: 441 KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ--EEKMRDQ 498
Query: 446 RLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERR-- 503
K +E R W ++E R ++ER ++Q K Q+EE K+ EE++ ++QE++
Sbjct: 499 EQKMWDQEERMW--EQDERLREKEERMREQKKMWQQEE------KMREEKKTQEQEKKTW 550
Query: 504 -EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562
+++ RE+E RE+ K +EEEE ++++ E++++ ++E+ REQ EEK EQE
Sbjct: 551 DQEEKMREEERMREREKKMREEEEMMREQ---EEKMQEQEEKMREQ-----EEKMWEQEE 602
Query: 563 REQRLKREQEERRDQLLKREEERRQQRLKREQEERL---EQRLKREEVERLEQEER-REQ 618
+ Q + + E+ +++ ++EEE + Q EQEE + E++++ +E + EQEE+ REQ
Sbjct: 603 KMQEQEEKMWEQEEKMWEQEEEDKMQ----EQEEMMWEQEEKMQEQEEKMWEQEEKMREQ 658
Query: 619 RLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERL---EQRLKRE 675
K E EE+ + Q K EQEE+ Q Q +++ REQ K +EE++ E+++ +
Sbjct: 659 EEKMREQEEKMQGQEEKMREQEEKMQGQ----EEKMREQEEKMRGQEEKMWGQEEKMWGQ 714
Query: 676 HEEERREQELAEEEQ--EQARERIKSRIPK 703
E+ ++E+ E+E+ +E+++ R+P+
Sbjct: 715 EEKMWGQEEMREKEERIRDQKEKMQERLPE 744
Score = 266 bits (679), Expect = 2e-70
Identities = 209/738 (28%), Positives = 403/738 (54%), Gaps = 91/738 (12%)
Query: 354 EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQ---LRREQQLRRE 410
++ + ++ LRRE E + ++ Q+ E L Q R+ + L + L
Sbjct: 73 KKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAG- 131
Query: 411 QQLRREQQLRREQQLRREQEEERHEQ--KHEQERREQRLKREQEERRDWLKREEETERHE 468
+L E Q H++ ++ +E ++R E R+ + EE +++
Sbjct: 132 -RLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNA 190
Query: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 528
+ + K +L ++ E ++L +E + + ER + L + Q ++ + RQEEE R
Sbjct: 191 ELQEKLRLAESEKSE-----IQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELRE 245
Query: 529 QQRLRSEQQLRREQEE--RREQLLKREEEKRLEQE----RREQRLKREQEERRDQLLKRE 582
Q E+++R+++E+ R+E+ L+ +E K EQE R+E+RL+ +++E R+Q +
Sbjct: 246 Q-----EKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQ---EK 297
Query: 583 EERRQQRLKREQEERL---EQRLKREEVERLEQEE---RREQRLKREEPEEERRQQLLKS 636
E R Q++L REQEE++ E+++ +E + EQEE R+E+RL E E++ R+Q K
Sbjct: 298 ELREQKKL-REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL--WEQEKQMREQEQKM 354
Query: 637 EEQEER---RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQA 693
+QEER + ++LR +++ REQ E+EE+ E+ RE E++ RE+E EQE+
Sbjct: 355 RDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEK 414
Query: 694 RERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEK-----RRRRESELQW 748
++ + + W+ E E + +Q ++ + K Q + QEQEEK + R+ E W
Sbjct: 415 MQKQEENM----WEQE-EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW 469
Query: 749 QEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQ 808
+E++ RQ++ EQ W+ EEK Q++ + +++ +LR +E + REQ
Sbjct: 470 GQEKKMWRQEKMREQEDQ---MWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ 526
Query: 809 RFLPEEEEKEQRRRQRREREKELQFLEEE--EQLQRRERAQQLQEEEDGLQEDQERRRSQ 866
+ + ++EEK + ++ +E+EK+ EE+ E+ + RER ++++EEE+ ++E +E+ + Q
Sbjct: 527 KKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ 586
Query: 867 EQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQ 926
E E++R++++ + E+EE++Q E+ EK QE+
Sbjct: 587 E-----------------------------EKMREQEEKMWEQEEKMQ-EQEEKMWEQEE 616
Query: 927 ERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQER 986
+ +EEE QE+E+++ E+ EK + QE E+ + +++K++++EE++ +E + Q +
Sbjct: 617 KMWEQEEEDKMQEQEEMMWEQEEKMQEQE-EKMWEQEEKMREQEEKMREQE---EKMQGQ 672
Query: 987 EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
E+K RE+EE Q +E+ +RE+ EK R QE E+ + +++++ +EE++ +E E R +ER
Sbjct: 673 EEKMREQEEKMQGQEEKMREQEEKMRGQE-EKMWGQEEKMWGQEEKMWGQE-EMREKEER 730
Query: 1047 ERQYRE--EEELQQEEEQ 1062
R +E +E L + EE+
Sbjct: 731 IRDQKEKMQERLPEHEER 748
Score = 263 bits (672), Expect = 1e-69
Identities = 201/736 (27%), Positives = 411/736 (55%), Gaps = 87/736 (11%)
Query: 1097 EPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ-YREEEEVQQEEEQLLR 1155
E EK+ + + R E E Q ++L ++ ELE Y ++ ++ E+ L
Sbjct: 70 EDEKKASHQHQEALRREIEAQDHTIRILTCQKT-----ELETALYYSQDAARKFEDGNLG 124
Query: 1156 EEPEKRRRQ--------ELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQR 1207
E + R EL+R ++ ++ + E ++R YR +
Sbjct: 125 ESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEE 184
Query: 1208 QKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFR--QLEDSQLRDRQSQQ 1265
K+K E R E EK + K + E +F Q++ + L++ +Q
Sbjct: 185 LKKKNAELQEKLRLA-----ESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ 239
Query: 1266 DLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREER 1325
+ + L EQ+++ R+QE + W+Q +R E+E RE++++ +R++++ +E+++ LRE+
Sbjct: 240 EEE--LREQEKKIRKQEEKMWRQEER-LREQEGKMREQEEKMRRQEKRLREQEKELREQE 296
Query: 1326 EEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR 1385
+E R + +K RE+E+ +QE+EE + E++ K RE+E + Q + E+E+++R
Sbjct: 297 KELREQ----KKLREQEEQMQEQEE---KMWEQEEKMREQEEKMWRQEERLWEQEKQMRE 349
Query: 1386 QERERKFLKE---EQQLRCQEREQQLRQ-----DRDRKFREEEQQLSRQERDRKFREEEQ 1437
QE++ + +E EQ R +E+E+++R+ +++ K +EEE+ +ER++K REEE+
Sbjct: 350 QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERI---REREKKMREEEE 406
Query: 1438 QVRRQERERKFLEE---EQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQL 1494
+R QE + + EE EQ+ ++ + ++ E+++ L E+E+ Q E++ K E+E+++
Sbjct: 407 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ----EQEEKIWEQEEKI 462
Query: 1495 RRQE----------RDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQE 1544
R QE R K REQE + E E K ++EQ++ Q+ + +++++LR +E
Sbjct: 463 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE--RMWEQDERLREKE 520
Query: 1545 RGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRL-EEQKVRRQEQERKFMEDEQQ 1603
+R +++ + +++EE++R+E++ Q+ ++ D++ ++ EE+++R E+E+K E+E+
Sbjct: 521 ---ERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR--EREKKMREEEEM 575
Query: 1604 LRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRH 1663
+R QE + QE++ K RE E+ + E+EE+ QE++ K E+E ++ QE E +++
Sbjct: 576 MREQE---EKMQEQEEKMREQEEKMWEQEEKM---QEQEEKMWEQEEKMWEQEEEDKMQE 629
Query: 1664 DRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELER 1723
+ + +EE++ +EQ+ + E++ K RE+E+++R E+E K +E+++R QE E+
Sbjct: 630 QEEMMWEQEEKM----QEQEEKMWEQEEKMREQEEKMR--EQEEKMQGQEEKMREQE-EK 682
Query: 1724 KFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQER 1783
+EE++R+ ++E++R QE K+ +E+ +EE+ ++E K EE++R ++
Sbjct: 683 MQGQEEKMRE--QEEKMRGQE--EKMWGQEEKMWGQEEKMWGQEEMREK---EERIRDQK 735
Query: 1784 EEQQLRSQESDRKFRE 1799
E+ Q R E + + E
Sbjct: 736 EKMQERLPEHEERCSE 751
Score = 261 bits (666), Expect = 6e-69
Identities = 168/596 (28%), Positives = 352/596 (59%), Gaps = 36/596 (6%)
Query: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQS 155
+E K+ + +E L R E ++ + ++L+ + + + Q Q L E +
Sbjct: 183 EELKKKNAELQEKL---RLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ 239
Query: 156 EKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRREL 215
E++ R +++ ++++E++WRQ + +E+E + E+E+ + E E + + +EL
Sbjct: 240 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKEL 299
Query: 216 LELRRKGREEKQQQRRER----QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQREL 271
E ++ +E+Q Q +E Q+ +E+EEK WR+ E + +E++ ++E+ R +E
Sbjct: 300 REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
Query: 272 QEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQ 331
+ E+ R E++E RE+++ +Q+++++ E+++ R++E++ RE++E REQ+E+ ++Q
Sbjct: 360 RMWEQDERLREKEERMREQEKMWEQEEKMQEEERI-REREKKMREEEETMREQEEKMQKQ 418
Query: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE--RREQQLRREQQLRREQQL 389
EE +Q +E+ +QQ EQ+E+ EQ+ +EQEE+ +E+++R ++++ +++
Sbjct: 419 EENMWEQ----EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK 474
Query: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
Q+ REQ+ +Q +E+++R ++Q +Q+ R +++ER +K E+ R ++++ +
Sbjct: 475 MWRQEKMREQE---DQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQ 531
Query: 450 EQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR 509
++E+ R+ E++T+ E++ Q+ K +EE RER K+ EEE E +E++++
Sbjct: 532 QEEKMRE----EKKTQEQEKKTWDQEEKMREEERMREREKKMREEE--EMMREQEEKMQE 585
Query: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
++E+ REQ K E+EE++Q++ E+++ ++E+ EQ EE+K EQE +
Sbjct: 586 QEEKMREQEEKMWEQEEKMQEQ---EEKMWEQEEKMWEQ---EEEDKMQEQEEMMWEQEE 639
Query: 570 EQEERRDQLLKREEERRQQRLK-REQEERLEQRLKREEVERLEQEERREQRLKREEPEEE 628
+ +E+ +++ ++EE+ R+Q K REQEE+++ +EE R ++E+ + Q K E EE+
Sbjct: 640 KMQEQEEKMWEQEEKMREQEEKMREQEEKMQ---GQEEKMREQEEKMQGQEEKMREQEEK 696
Query: 629 RRQQLLKSEEQEERR--QQQLRREQQERREQRLKREEEEERLEQRLKREHEEERRE 682
R Q K QEE+ Q++ Q+E RE+ + +++E++++RL EHEE E
Sbjct: 697 MRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLP-EHEERCSE 751
Score = 257 bits (657), Expect = 7e-68
Identities = 201/746 (26%), Positives = 411/746 (55%), Gaps = 80/746 (10%)
Query: 947 EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLRE 1006
E EK+ + + R++ + Q ++L ++ + Y ++ ++ E+ L E
Sbjct: 70 EDEKKASHQHQEALRREIEAQDHTIRIL----TCQKTELETALYYSQDAARKFEDGNLGE 125
Query: 1007 EREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGE 1066
++ R + ELQ+ + ++ R E + R+ L+ + E
Sbjct: 126 SKDLAGRLH--HSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNE 183
Query: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE 1126
E + ++ EL+ + R E E+ ++ E +R+ ER + + + +E++ R+
Sbjct: 184 ELK-KKNAELQEKLRLAES---EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQ 239
Query: 1127 EREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLRE 1186
E E R E E++ R++EE +E+ LRE+ K R QE E+++++E++L
Sbjct: 240 EEELR---EQEKKIRKQEEKMWRQEERLREQEGKMREQE--------EKMRRQEKRL--R 286
Query: 1187 EQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE 1246
EQEK +E+E++ RE+++L+ Q+ + + ++E WE E++ ++ K++ R+
Sbjct: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEK-------MWEQEEKMREQEEKMW---RQ 336
Query: 1247 NEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE 1306
E+ + E Q +D + + EQ ER RE+E R +++++ + +EE+++ EE+
Sbjct: 337 EERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE-ERMREQEKMWEQEEKMQEEER-- 393
Query: 1307 AKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEE 1366
+ R++K +EE++ +RE+ EEK ++QE + +E E+E Q R E+ K E+E
Sbjct: 394 IREREKKMREEEETMREQ-EEKMQKQEENMWEQE------EKEWQQQRLPEQKEKLWEQE 446
Query: 1367 LRHQEQGRKFLEEEQRLRRQE----RERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQ 1422
+ QEQ K E+E+++R QE +E+K ++E + +E+E Q+ +++ K R++EQ+
Sbjct: 447 -KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE---KMREQEDQM-WEQEEKMRDQEQK 501
Query: 1423 LSRQ-----ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE---RE 1474
+ Q E+D + RE+E+++R Q +K ++E+++R+E+ + +E++ QE RE
Sbjct: 502 MWDQEERMWEQDERLREKEERMREQ---KKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE 558
Query: 1475 EQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFL 1534
E+++ +ER++K EEE+ +R QE K +EQE + +E E K E+E+++ Q+++ K
Sbjct: 559 EERM--REREKKMREEEEMMREQE--EKMQEQEEKMREQEEKMWEQEEKM--QEQEEKMW 612
Query: 1535 QEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE 1594
++E+++ QE + + Q+++ E+E+ QE+EE+ E++ K R +E+K+R EQE
Sbjct: 613 EQEEKMWEQEE-EDKMQEQEEMMWEQEEKMQEQEEKM---WEQEEKMREQEEKMR--EQE 666
Query: 1595 RKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRR 1654
K E+++R QE + Q ++E K RE E+ ++ +EE+ ++E + + +EE +
Sbjct: 667 EKMQGQEEKMREQEEKMQGQEE---KMREQEEKMRGQEEKMWGQEE--KMWGQEEKMWGQ 721
Query: 1655 QEREQQLRHDRDRKFREEEQLLQEGE 1680
+E ++ RD+K + +E+L + E
Sbjct: 722 EEMREKEERIRDQKEKMQERLPEHEE 747
Score = 254 bits (648), Expect = 7e-67
Identities = 183/621 (29%), Positives = 360/621 (57%), Gaps = 60/621 (9%)
Query: 1297 EQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQ 1356
++ +R ++ K RD S E + E K++ E K R E E+ E L +
Sbjct: 155 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAES---EKSEIQLNVK 211
Query: 1357 ERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKF 1416
E RK E+ + L + Q QE + ++E++LR E+E+++R+ ++ +
Sbjct: 212 ELKRKL--------ERAKFLLPQVQTNTLQE---EMWRQEEELR--EQEKKIRKQEEKMW 258
Query: 1417 REEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQ 1476
R+EE+ +E++ K RE+E+++RRQE+ + E+E++LR E+ ++ RE+++L +E+EEQ
Sbjct: 259 RQEERL---REQEGKMREQEEKMRRQEKRLR--EQEKELR-EQEKELREQKKL-REQEEQ 311
Query: 1477 QLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQE 1536
QE++ K E+E+++R QE K QE R E E++ E+EQ++ R Q +R + Q+
Sbjct: 312 M---QEQEEKMWEQEEKMREQEE--KMWRQEERLWEQEKQMREQEQKM-RDQEERMWEQD 365
Query: 1537 EQQLRRQER--GQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE 1594
E+ ++ER Q++ +++ K +EEE++R ER++K R EE+ +R QE++
Sbjct: 366 ERLREKEERMREQEKMWEQEEKMQEEERIR-----------EREKKMREEEETMREQEEK 414
Query: 1595 RKFMEDEQ-QLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLR 1653
+ E+ + +E QQQ E+ K E E++ QE+EE+ ++E+ R E Q +
Sbjct: 415 MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM-QEQEEKIWEQEEKIRDQEEMWGQEK 473
Query: 1654 RQEREQQLRHDRDRKFREEEQLLQEGE---EQQLRRQERDRKFREEEQQLRRQERERKFL 1710
+ R++++R D+ + +EE++ + + +Q+ R E+D + RE+E+++R Q +K
Sbjct: 474 KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ---KKMW 530
Query: 1711 QEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERD 1770
Q+E+++R ++ ++ ++ ++E +E+ R +ER +K+ EEE++ E+EE+ QE++
Sbjct: 531 QQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKM---QEQE 587
Query: 1771 RKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQL 1830
K RE+E+ E+EE + QE + K E+E+ E+EE+ +Q + WE+E+ ++
Sbjct: 588 EKMREQEEKMWEQEE---KMQEQEEKMWEQEEKMWEQEEEDKMQEQEE--MMWEQEE-KM 641
Query: 1831 EEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQK 1890
+EQE+++ ++ ++ EE+ QE+ + ++E +E+E+K Q +E K+RE+ + + +
Sbjct: 642 QEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEK-MQGQEEKMREQEEKMRGQ 700
Query: 1891 EEQRHRQVGEIKSQEGKGHGR 1911
EE+ Q ++ QE K G+
Sbjct: 701 EEKMWGQEEKMWGQEEKMWGQ 721
Score = 237 bits (605), Expect = 7e-62
Identities = 155/542 (28%), Positives = 337/542 (62%), Gaps = 49/542 (9%)
Query: 91 QATGLDEEK-RARCDGKESLLQDRRQEEDQRRFEPRDRQLE-----EEPGQRRRQKR-QE 143
Q L EE R + +E + R+QEE R E R R+ E +E RR++KR +E
Sbjct: 228 QTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLRE 287
Query: 144 QERELAEGEEQSEKQERLEQRDRQRRDEE--LWRQRQEWQEREERR-AEEEQLQSCKGHE 200
QE+EL E E++ +Q++L +++ Q +++E +W Q ++ +E+EE+ +EE+L +
Sbjct: 288 QEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQM 347
Query: 201 TEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEE----EKEWRKRETVLRKE 256
E+ E+++R +E + R ++++R Q++++++EE E+ R+RE +R+E
Sbjct: 348 REQ---EQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREE 404
Query: 257 EEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERRE 316
EE ++E+E ++Q++EE + + E +E +++R E++++ EQ+ ++QEE+ E
Sbjct: 405 EETMREQE----EKMQKQEENMWEQEEKEWQQQRLPEQKEK---LWEQEKMQEQEEKIWE 457
Query: 317 QQEERREQQERREQQEERREQQLRREQEER--REQQLRREQEEERREQQLRREQEEER-- 372
Q+E+ R+Q+E Q+++ Q+ REQE++ +++ R+QE++ +Q+ R +++ER
Sbjct: 458 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLR 517
Query: 373 -REQQLRREQQLRREQQLRREQQLRREQQLR---REQQLRREQQLR-REQQLRREQQLRR 427
+E+++R ++++ ++++ RE++ +EQ+ + +E+++R E+++R RE+++R E+++ R
Sbjct: 518 EKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR 577
Query: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
EQEE+ EQ+ + +E+++ EQEE+ +E+E + EQE + + + + + + +E
Sbjct: 578 EQEEKMQEQEEKMREQEEKM-WEQEEK----MQEQEEKMWEQEEKMWEQEEEDKMQEQEE 632
Query: 488 WLKLEEEERREQQER---REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEE 544
+ +EE+ +EQ+E+ +E+++R ++E+ REQ K Q +EE+++++ E++++ ++E+
Sbjct: 633 MMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQ---EEKMQGQEEK 689
Query: 545 RREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR 604
REQ EEK QE + + + + +++ +EE R ++ R+Q+E++++RL
Sbjct: 690 MREQ-----EEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPE 744
Query: 605 EE 606
E
Sbjct: 745 HE 746
Score = 229 bits (583), Expect = 3e-59
Identities = 177/646 (27%), Positives = 359/646 (55%), Gaps = 81/646 (12%)
Query: 1292 HFPEEEQLEREEQKEAKRRDRKSQEEK-QLLREEREEKRRR----QETDRKFR-----EE 1341
H PE+E+ + +EA RR+ ++Q+ ++L ++ E Q+ RKF E
Sbjct: 67 HSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGES 126
Query: 1342 EQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRC 1401
+ L E R H++ R ++EE + ER+ L+ +
Sbjct: 127 KDLAGRLHHSWHFAGELQRALSAVSTWHKKADR-YIEELTK----ERDALSLELYRNTIT 181
Query: 1402 QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHR 1461
E ++ + K R E + S + + K +++R+ KFL + Q +
Sbjct: 182 NEELKKKNAELQEKLRLAESEKSEIQLNVK------ELKRKLERAKFLLPQVQTNTLQEE 235
Query: 1462 KFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEE 1521
+R+EE+L ++ E+++ +QE K +E++LR QE K REQE + + E++ E+E
Sbjct: 236 MWRQEEELREQ--EKKIRKQEE--KMWRQEERLREQEG--KMREQEEKMRRQEKRLREQE 289
Query: 1522 QQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKF 1581
++L Q+++ L+E+++LR QE ++ Q+++ K E+E+ +E+EE+ ++ER
Sbjct: 290 KELREQEKE---LREQKKLREQE---EQMQEQEEKMWEQEEKMREQEEKMWRQEER---- 339
Query: 1582 RLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQ-- 1639
L EQ+ + +EQE+K + E+++ Q+ ++LR E++ + RE E++ ++ E+ Q +
Sbjct: 340 -LWEQEKQMREQEQKMRDQEERMWEQD--ERLR-EKEERMREQEKMWEQEEKMQEEERIR 395
Query: 1640 ERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEE--QQLRRQERDRKFREEE 1697
ER++K EEE +R QE + Q ++EE + ++ E+ QQ R E+ K E+E
Sbjct: 396 EREKKMREEEETMREQEEKMQ---------KQEENMWEQEEKEWQQQRLPEQKEKLWEQE 446
Query: 1698 QQLRRQERERKFLQEEQQLRRQE----LERKFREEEQLRQETEQ-----EQLRRQERYRK 1748
+ QE+E K ++E+++R QE E+K +E++R++ +Q E++R QE+ K
Sbjct: 447 KM---QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ--K 501
Query: 1749 ILEEEQLRPEREEQQLRRQERDRK----FREEEQLRQER--EEQQLRSQESDRKFREEEQ 1802
+ ++E+ E++E+ ++ER R+ +++EE++R+E+ +EQ+ ++ + + K REEE+
Sbjct: 502 MWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEER 561
Query: 1803 LRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQ 1862
+R ERE++ R+ + E++ +++EQE+++R++ ++ + EE+ QE+ E++
Sbjct: 562 MR-EREKKM-----REEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615
Query: 1863 E-LWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
E +W++EE+ + QE+E + E+ + Q++EE+ Q +++ QE K
Sbjct: 616 EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEK 661
Score = 60.5 bits (145), Expect = 2e-08
Identities = 40/169 (23%), Positives = 89/169 (52%), Gaps = 13/169 (7%)
Query: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQR----------RRQKRQEQER 146
EEK + K +++ QE++++ +E ++ E+E + + +K QEQE
Sbjct: 587 EEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE 646
Query: 147 ELAEGEEQSEKQERL--EQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
++ E EE+ +QE EQ ++ + EE R+++E + +E + E++ + +G E + +
Sbjct: 647 KMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQE-EKMRGQEEKMW 705
Query: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVL 253
EE++ +E ++ EK+++ R++++++ + E E R E L
Sbjct: 706 GQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCL 754
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 283 bits (724), Expect = 1e-75
Identities = 201/694 (28%), Positives = 407/694 (58%), Gaps = 94/694 (13%)
Query: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE--ERLEQRLKREEVERL 610
+E+K Q + R + E + ++L ++ Q L Q ++LE R+ + RL
Sbjct: 109 DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEA-RDLISRL 167
Query: 611 EQEER----REQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666
+ EQ L ++++ + ++ E +ER L + ++ LK E+
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIE-ELTKERDALSLELYRNTITDEELK--EKNA 224
Query: 667 RLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ 726
+L+++L+ E E+ E +L +E ++ ER K +P Q QL++EAD ++ S K
Sbjct: 225 KLQEKLQLV-ESEKSEIQLNVKELKRKLERAKLLLP--QQQLQAEADHLGKELQSVSAKL 281
Query: 727 EGQ--------RRRQEQEEKRRRRESELQ-WQE-----EERAHRQQ-----QEEEQRRDF 767
+ Q R Q+QEEK R+E ++Q W+E EE+ Q+ QEE+ RR
Sbjct: 282 QAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 341
Query: 768 TWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRER 827
W+ EEK +R Q E EE+ +R++ + E+EEK RR++
Sbjct: 342 EMMWEKEEK-------------MRRQEEMMWEKEEKMRRQEEMMWEKEEK-MRRQEEMMW 387
Query: 828 EKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRH 887
EKE + E EE++ +E+ ++ +E+ ++++E+ R QE+R++Q+ + +EE+ R +
Sbjct: 388 EKEEKIRELEEKMHEQEKIREQEEK----RQEEEKIREQEKRQEQEAKMWRQEEKIREQ- 442
Query: 888 TLYAKPALQEQLRKEQQLLQEEEEELQREE--REKRRRQEQERQYREEEQLQQEEE---- 941
+E++R++++ + +EE++ +E RE+ +RQEQE +R+EE++ ++EE
Sbjct: 443 --------EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQ 494
Query: 942 -QLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEE 1000
+ + E+ EK R+QE E+ +R+++K++++EE++ E+ EK RQE +K RE+EE+ +EE
Sbjct: 495 KEKMHEQEEKIRKQE-EKVWRQEEKIREQEEKIR-EQEEKMWRQE--EKIREQEEMWREE 550
Query: 1001 EQLLREER---EKRRRQEWERQYRKKDELQQEEEQLLREE-----REKRRLQERERQYRE 1052
E++ +E+ E++R+++ ++ +R++++++++EE++ R+E +E++R ++ E+ +++
Sbjct: 551 EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610
Query: 1053 EEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE 1112
EE+++++EE++ +E + R ++E + R++EE+ QE+E+ + E+ EK C +
Sbjct: 611 EEKIREQEEKIQEQEEKIREQEE---KIREQEEMTQEQEEKMGEQEEK--------MCEQ 659
Query: 1113 EEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE 1172
EE++Q++EE + R+E + R E E++ RE+EE +E+E++++E+ EK QE E+ +
Sbjct: 660 EEKMQEQEETMWRQEEKIR---EQEKKIREQEEKIREQEEMMQEQEEKMWEQE-EKMCEQ 715
Query: 1173 EEELQQEEEQLLREEQEKRRQERERQYREEEELQ 1206
EE++Q++EE++ R+E EK ++ R ++EE++Q
Sbjct: 716 EEKMQEQEEKMRRQE-EKMWEQEVRLRQQEEKMQ 748
Score = 273 bits (699), Expect = 9e-73
Identities = 218/761 (28%), Positives = 423/761 (55%), Gaps = 124/761 (16%)
Query: 678 EERREQELAEEEQEQARERIKSRIPKWQWQLESEA-DARQSKVYSRPRKQ---------- 726
+E R+ +LAE A+E++ P+ + + A D ++ K+ + +
Sbjct: 53 KETRQSKLAE-----AKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSP 107
Query: 727 EGQRRRQEQEEKRRRRE---------------SELQWQEEERAHRQQQEEEQRRDF---- 767
E +++ Q ++ RRE +ELQ H +Q E + RD
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 768 --TWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQRE-------QRFLPEEEEKE 818
+W++ E + Q LSA +++ +R + E ++R+ + + +EE KE
Sbjct: 168 HDSWKFAGELE-----QALSAVATQKKKADRYIE-ELTKERDALSLELYRNTITDEELKE 221
Query: 819 -----QRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQK 873
Q + Q E EK L +E ++ ERA+ L ++ LQ + + + Q K
Sbjct: 222 KNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ-LQAEADHLGKELQSVSAK 280
Query: 874 WRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREE 933
+ Q+EE R +E++ ++++ +QE EE++Q +E + R EQE + RE+
Sbjct: 281 LQAQVEENELWNR----LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR---EQEEKIREQ 333
Query: 934 EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQE-----REK 988
E+ + +E+++ E+ EK RRQE E + K++K++++EE ++ E+ EK RRQE +E+
Sbjct: 334 EEKMRRQEEMMWEKEEKMRRQE-EMMWEKEEKMRRQEE-MMWEKEEKMRRQEEMMWEKEE 391
Query: 989 KYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE---EEQLLREEREKRRLQE 1045
K RE EE E+E++ RE+ EKR+ +E R+ K+ E + + +E+ +RE+ EK R QE
Sbjct: 392 KIRELEEKMHEQEKI-REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 450
Query: 1046 RERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEE-----QLLREEPEK 1100
+ + +R+EE++ ++E+ RE +RQE E +R+EE++ ++EE + + E+ EK
Sbjct: 451 K-KMWRQEEKIHEQEKI-----REEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEK 504
Query: 1101 RRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREE--- 1157
R+QE E+ R+EE+++++EE+ +RE+ EK RQ E + RE+EE+ +EEE++ +E
Sbjct: 505 IRKQE-EKVWRQEEKIREQEEK-IREQEEKMWRQ--EEKIREQEEMWREEEKMHEQEKIW 560
Query: 1158 PEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDE 1217
E++R+++ ++ +R+EE+++++EE++ R+E++ R QE +RQ +EE++ +Q+ K R
Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQ-EQEEKMWKQEEKIR---- 615
Query: 1218 DQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQER 1277
E+E +++ + E+ R+ E+ + Q+ + +GEQ+E+
Sbjct: 616 ------------EQEEKIQE--------QEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Query: 1278 DREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRK 1337
EQE + +Q + + +EE++ RE++K+ + ++ K +E++++++E+ E + E + K
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKI-REQEKKIREQEEKIREQEEMMQEQEE---KMWEQEEK 711
Query: 1338 FREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLE 1378
E+E+ +QE+EE+ +RRQE K E+E+R ++Q K E
Sbjct: 712 MCEQEEKMQEQEEK-MRRQE--EKMWEQEVRLRQQEEKMQE 749
Score = 273 bits (697), Expect = 2e-72
Identities = 205/747 (27%), Positives = 398/747 (53%), Gaps = 115/747 (15%)
Query: 812 PEEEEKEQRRRQ---RREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQ 868
PE+E+K + Q RRE E ++ + Q+ E L + +++ + R
Sbjct: 107 PEDEQKASHQHQEALRRELEAQVHTIRILT-CQKTELQMALYYSQHAVKQLEGEARDLIS 165
Query: 869 RRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQER 928
R W++ E E+ A A+ Q +K + ++E +E E R +
Sbjct: 166 RLHDSWKFAGELEQ--------ALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE 217
Query: 929 QYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK 988
+ +E+ QE+ QL+ E+ + + +E +R+ ER K
Sbjct: 218 ELKEKNAKLQEKLQLVESEKSEIQLNVKEL----------------------KRKLERAK 255
Query: 989 KYREEEELQQEEEQLLREERE---KRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQE 1045
+++LQ E + L +E + K + Q E + + QQEE+ +EE+ +QE
Sbjct: 256 LLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEK----IQE 311
Query: 1046 RERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQE 1105
E + +E+EE +E+E+ + E+ E RRQE E + KEE+++++EE + +E + RR++E
Sbjct: 312 WEEKIQEQEEKIREQEEKIREQEEKMRRQE-EMMWEKEEKMRRQEEMMWEKEEKMRRQEE 370
Query: 1106 ----RERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKR 1161
+E + R +EE+ E+E+ +RE EK QE + RE+EE +QEEE++ E EKR
Sbjct: 371 MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE---KIREQEEKRQEEEKI--REQEKR 425
Query: 1162 RRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRS 1221
+ QE + +R+EE++ RE++EK R++ ++ +R+EE++ Q ++ R+E++R
Sbjct: 426 QEQEA-KMWRQEEKI--------REQEEKIREQEKKMWRQEEKIHEQ---EKIREEEKRQ 473
Query: 1222 DLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQ 1281
+ + W E+ K++ + E +RQ E + EQ+E+ R+Q
Sbjct: 474 EQEEMWRQEE-------KIH---EQEEIWRQKEK---------------MHEQEEKIRKQ 508
Query: 1282 ERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREE 1341
E + W+Q ++ +EE++ RE++++ R++ K +E++++ REE + + + + + R+E
Sbjct: 509 EEKVWRQEEKIREQEEKI-REQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQE 567
Query: 1342 EQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRC 1401
++ R+E+ +R QE +EE++R QE+ +RQE+E K K+E+++R
Sbjct: 568 QEDKMWRQEEKIREQEEKVWRQEEKIREQEE-----------KRQEQEEKMWKQEEKIR- 615
Query: 1402 QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHR 1461
E+E+++ Q+++ K RE+E+++ QE +EQ+ + E+E K E+E++++++
Sbjct: 616 -EQEEKI-QEQEEKIREQEEKIREQEE----MTQEQEEKMGEQEEKMCEQEEKMQEQEET 669
Query: 1462 KFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEE 1521
+R+EE++ EQ+ +E++ K E+E+ + QE++ K EQE + E E K E+E
Sbjct: 670 MWRQEEKI----REQEKKIREQEEKIREQEEMM--QEQEEKMWEQEEKMCEQEEKMQEQE 723
Query: 1522 QQLHRQQRQRKFLQEEQQLRRQERGQQ 1548
+++ RQ + K ++E +LR+QE Q
Sbjct: 724 EKMRRQ--EEKMWEQEVRLRQQEEKMQ 748
Score = 267 bits (682), Expect = 9e-71
Identities = 202/722 (27%), Positives = 398/722 (55%), Gaps = 95/722 (13%)
Query: 583 EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642
+E RQ +L +E+ + + + +++++ E S E E++
Sbjct: 53 KETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQK 112
Query: 643 ----RQQQLRREQQER--------------------REQRLKREEEEERLEQRLKREHEE 678
Q+ LRRE + + + +K+ E E R + R H+
Sbjct: 113 ASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEAR--DLISRLHDS 170
Query: 679 ERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEK 738
+ EL + A + K + ++ +L E DA ++Y E E +EK
Sbjct: 171 WKFAGELEQALSAVATQ--KKKADRYIEELTKERDALSLELYRNTITDE------ELKEK 222
Query: 739 RRRRESELQWQEEERAHRQQQEEEQRRDFT--------WQWQAEEKSERGRQRLSARPPL 790
+ + +LQ E E++ Q +E +R Q QAE G++ S L
Sbjct: 223 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA-DHLGKELQSVSAKL 281
Query: 791 REQ-RERQLRAEERQQREQRFLPEEE-----EKEQRRRQRREREKELQFLEEEEQLQRRE 844
+ Q E +L QQ+E++ +EE E++ + ++ + RE+E + E+EE+++R+E
Sbjct: 282 QAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 341
Query: 845 RAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRK--- 901
+EE+ QE+ + ++ RR ++ W+ EE+ +R+ ++ K +L +
Sbjct: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 401
Query: 902 EQQLLQEEEEELQREE--REKRRRQEQE-RQYREEEQLQQEEEQLLREE----------- 947
EQ+ ++E+EE+ Q EE RE+ +RQEQE + +R+EE+++++EE++ +E
Sbjct: 402 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 461
Query: 948 -----REKRRRQERERQYRKDKKLQQKEE-----QLLGEEPEKRRRQEREKKYREEEELQ 997
RE+ +RQE+E +R+++K+ ++EE + + E+ EK R+QE EK +R+EE+++
Sbjct: 462 EQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQE-EKVWRQEEKIR 520
Query: 998 QEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREER---EKRRLQERERQYREEE 1054
++EE++ RE+ EK RQE + R+++E+ +EEE++ +E+ E++R ++ ++ +R+EE
Sbjct: 521 EQEEKI-REQEEKMWRQE--EKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEE 577
Query: 1055 ELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEE 1114
+++++EE++ +E + R ++E +RQ ++E+ +QEE+ +RE+ EK QE+E + RE+E
Sbjct: 578 KIREQEEKVWRQEEKIREQEE-KRQEQEEKMWKQEEK--IREQEEKI--QEQEEKIREQE 632
Query: 1115 ELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEE 1174
E +E+E++ +E+ EK QE E+ +EE++Q++EE + R+E EK R Q E++ RE+E
Sbjct: 633 EKIREQEEMTQEQEEKMGEQE-EKMCEQEEKMQEQEETMWRQE-EKIREQ--EKKIREQE 688
Query: 1175 ELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDE---DQRSDLKWQWEPEK 1231
E +E+E++++E++EK ++ E+ +EE++Q Q+ K R ++E +Q L+ Q E +
Sbjct: 689 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
Query: 1232 EN 1233
E+
Sbjct: 749 EH 750
Score = 261 bits (666), Expect = 6e-69
Identities = 195/634 (30%), Positives = 363/634 (57%), Gaps = 58/634 (9%)
Query: 37 LEREFGAVLRRPHDP-KTVDLILELLDLDSNGRVDFNEFLLFIFKVAQACYYALGQATGL 95
LE E ++ R HD K + + L + + + ++ + K A L + T
Sbjct: 156 LEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTIT 215
Query: 96 DEE---KRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEE----PGQRRRQKRQEQEREL 148
DEE K A+ K L++ + E Q + R+LE P Q+ + + +EL
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEI-QLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 274
Query: 149 ----AEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
A+ + Q E+ E L R Q+++E++WRQ ++ QE EE+ E+E+ + E +
Sbjct: 275 QSVSAKLQAQVEENE-LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE--KIREQEEKIR 331
Query: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE 264
EE++RR+E + ++ + +Q++ ++ + +EE W K E + R+EE ++EE
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 391
Query: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
+ REL+E+ + K+ QE +R+ +E+ ++Q++ + ++ +QEE+ REQ+E+ REQ
Sbjct: 392 --KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 449
Query: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
+++ +QEE+ EQE+ RE++ R+EQEE R+++ EQEE R+++ EQ+ +
Sbjct: 450 EKKMWRQEEKIH-----EQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEK 504
Query: 385 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQK-HEQERR 443
+Q E+ R+E+++R +++ REQ+ E+ R+E+++R ++E R E+K HEQE+
Sbjct: 505 IRKQ--EEKVWRQEEKIREQEEKIREQE---EKMWRQEEKIREQEEMWREEEKMHEQEKI 559
Query: 444 EQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERR 503
+ KR+++E + W + E+ E+ E+ R+++ R+QEE+R +E+ E+ ++
Sbjct: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKR---------QEQEEKMWKQ 610
Query: 504 EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR 563
E+++R ++E+ +EQ K +E+EE ++R ++++ +EQEE+ + +EEK EQE +
Sbjct: 611 EEKIREQEEKIQEQEEKIREQEE----KIREQEEMTQEQEEK----MGEQEEKMCEQEEK 662
Query: 564 EQRLKREQEERRDQLLKREEERRQQRLK-REQEERL---EQRLKREEVERLEQEERR-EQ 618
Q EQEE + ++EE+ R+Q K REQEE++ E+ ++ +E + EQEE+ EQ
Sbjct: 663 MQ----EQEE---TMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 715
Query: 619 RLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652
K +E EE+ R+Q K EQE R +QQ + Q+
Sbjct: 716 EEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 260 bits (665), Expect = 8e-69
Identities = 201/678 (29%), Positives = 380/678 (56%), Gaps = 69/678 (10%)
Query: 115 QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ-SEKQERLEQRDRQRRDEEL 173
Q+ + E R+LE + R Q+ E ++A Q + KQ E RD R +
Sbjct: 111 QKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDS 170
Query: 174 WRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRER 233
W+ E ++ A +++ EE E EL E K++ + +
Sbjct: 171 WKFAGELEQALSAVATQKKKAD---RYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
Query: 234 QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ-- 291
+ E E+ E + L+++ E+ + PQ+Q LQ E + L K E Q + + Q
Sbjct: 228 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ--LQAEADHLGK-ELQSVSAKLQAQ 284
Query: 292 -EEEQQQQRLRREQQLRRKQEEERREQQEERREQQER--REQQEERREQQLRREQEERRE 348
EE + RL ++Q+ + ++EE+ ++ EE+ ++QE REQ+E+ REQ+ E+ R+E
Sbjct: 285 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE---EKMRRQE 341
Query: 349 QQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQL--RREQQLRREQQ 406
+ + ++E+ RR++++ E+EE+ R Q+ E +E+++RR++++ +E+++R ++
Sbjct: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRQE---EMMWEKEEKMRRQEEMMWEKEEKIRELEE 398
Query: 407 LRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKR--EEET 464
EQ+ REQ+ +R+++ + ++E+R EQ+ + R+E++++ ++E+ R+ K+ +E
Sbjct: 399 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE 458
Query: 465 ERHEQERRKQQLKRDQEEE--RRERWLKLEEE---------ERREQQERREQQLRREQEE 513
+ HEQE+ +++ KR ++EE R+E + +EE E+ E+ ++E+++ R++E+
Sbjct: 459 KIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEK 518
Query: 514 RREQRLKRQEEEERL---QQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKRE 570
REQ K +E+EE++ ++++R ++++ RE+E+ EQ EEEKR EQE + R + +
Sbjct: 519 IREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEK 578
Query: 571 QEERRDQLLKREEERRQQRLKR-EQEERL---EQRLKREEVERLEQEER-REQRLKREEP 625
E+ +++ ++EE+ R+Q KR EQEE++ E++++ +E + EQEE+ REQ K E
Sbjct: 579 IREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQ 638
Query: 626 EEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQEL 685
EE ++Q K EQEE+ +Q E+ + +E+ + R+EE+ R +++ RE EE+ REQE
Sbjct: 639 EEMTQEQEEKMGEQEEKMCEQ--EEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696
Query: 686 AEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESE 745
+EQE+ W+ E + ++ K+ QEQEEK RR+E E
Sbjct: 697 MMQEQEEK-----------MWEQEEKMCEQEEKM-------------QEQEEKMRRQE-E 731
Query: 746 LQWQEEERAHRQQQEEEQ 763
W++E R RQQ+E+ Q
Sbjct: 732 KMWEQEVRL-RQQEEKMQ 748
Score = 259 bits (663), Expect = 1e-68
Identities = 192/663 (28%), Positives = 380/663 (57%), Gaps = 90/663 (13%)
Query: 977 EPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE 1036
E E++ + ++ R E E Q ++L ++ + + + Q+ K +L+ E L+
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVK-QLEGEARDLISR 166
Query: 1037 EREKRRLQ------------ERERQYREEEELQQEEEQLLGE-ERETRRRQELERQYRKE 1083
+ + ++++ R EEL +E + L E R T +EL+ + K
Sbjct: 167 LHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKL 226
Query: 1084 EE----LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE------------- 1126
+E ++ E+ ++ E +R+ ER + +++LQ E + L +E
Sbjct: 227 QEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE 286
Query: 1127 ERE---KRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQL 1183
E E + +Q+ E+ +R+EE++Q+ EE++ +E+ EK R QE + RE+EE + +E++
Sbjct: 287 ENELWNRLNQQQEEKMWRQEEKIQEWEEKI-QEQEEKIREQE--EKIREQEEKMRRQEEM 343
Query: 1184 LREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVY-- 1241
+ E++EK R++ E + +EE+++RQ+ ++E R + WE E++ + K++
Sbjct: 344 MWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 403
Query: 1242 CKGRENEQFRQLEDSQLRDRQSQQD-------LQHLLGEQQERDREQERRRWQQRDRHFP 1294
K RE E+ RQ E+ ++R+++ +Q+ + + EQ+E+ REQE++ W+Q ++
Sbjct: 404 EKIREQEEKRQ-EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE 462
Query: 1295 EE---EQLEREEQKEAKRRDRKSQEEKQLLRE-----EREEKRRRQE-----TDRKFREE 1341
+E E+ +R+EQ+E R++ K E++++ R+ E+EEK R+QE + K RE+
Sbjct: 463 QEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQ 522
Query: 1342 EQLLQEREEQPLRRQERDRK----FREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQ 1397
E+ ++E+EE+ R++E+ R+ +REEE H+++ K EEE +RQE+E K ++E+
Sbjct: 523 EEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQE--KIWEEE---KRQEQEDKMWRQEE 577
Query: 1398 QLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQ 1457
++R QE E+ RQ + K RE+E++ RQE++ K ++E+++R E+E K E+E+++R
Sbjct: 578 KIREQE-EKVWRQ--EEKIREQEEK--RQEQEEKMWKQEEKIR--EQEEKIQEQEEKIR- 629
Query: 1458 ERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQE-----RDRKFREQELRSQE 1512
E+ K RE+E++ QE+EE+ E++ K E+E++++ QE ++ K REQE + +E
Sbjct: 630 EQEEKIREQEEMTQEQEEKM---GEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIRE 686
Query: 1513 PERKFLEEEQQLHRQQRQRKFLQE----EQQLRRQERGQQRRQDRDRKFREEEQLRQERE 1568
E K E+E+ + ++Q ++ + QE EQ+ + QE+ ++ R+ ++ + +E +LRQ+ E
Sbjct: 687 QEEKIREQEEMM-QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 745
Query: 1569 EQQ 1571
+ Q
Sbjct: 746 KMQ 748
Score = 259 bits (661), Expect = 2e-68
Identities = 172/587 (29%), Positives = 363/587 (61%), Gaps = 72/587 (12%)
Query: 143 EQERELAEGEEQSEKQERLEQRDRQRRDE---ELWRQRQEWQEREERRAE-EEQLQSCKG 198
E E+ L+ Q +K +R + + RD EL+R +E +E+ A+ +E+LQ +
Sbjct: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
Query: 199 HETEEFPDEEQLRRR----ELL--------ELRRKGRE--------EKQQQRRERQDRVF 238
++E + ++L+R+ +LL E G+E + Q + E +R+
Sbjct: 236 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295
Query: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298
Q++EEK WR+ E + ++ EEK+QE+E +++E+EE++R+ E +++RR+ + ++++
Sbjct: 296 QQQEEKMWRQEEKI-QEWEEKIQEQE----EKIREQEEKIREQE-EKMRRQEEMMWEKEE 349
Query: 299 RLRREQQLRRKQEEERREQQEERREQQERREQQEE---RREQQLRR------EQEERREQ 349
++RR++++ ++EE+ R Q+E E++E+ +QEE +E+++R EQE+ REQ
Sbjct: 350 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 409
Query: 350 QLRREQEEERREQQLRREQEEE--RREQQLRREQQLRREQQ---LRREQQLRREQQLRRE 404
+ +R++EE+ REQ+ R+EQE + R+E+++R +++ REQ+ R+E+++ ++++R E
Sbjct: 410 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE 469
Query: 405 QQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQE---ERRDWLKRE 461
++ + ++++ R+++ EQ+ Q+E+ HEQ+ + ++E+++ R++E E+ + ++ +
Sbjct: 470 EKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQ 529
Query: 462 EETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQE----RREQQLR-------RE 510
EE ++E+ ++Q + +EEE+ K+ EEE+R++QE R+E+++R R+
Sbjct: 530 EEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQ 589
Query: 511 QEERREQRLKRQEEEERL---QQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL 567
+E+ REQ KRQE+EE++ ++++R +++ +EQEE+ ++ +EEK EQE Q
Sbjct: 590 EEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEK----IREQEEKIREQEEMTQEQ 645
Query: 568 KREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEER-REQRLKREEPE 626
+ + E+ +++ ++EE+ ++Q E R E++++ +E + EQEE+ REQ +E E
Sbjct: 646 EEKMGEQEEKMCEQEEKMQEQ---EETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQE 702
Query: 627 EERRQQLLKSEEQEERRQQQ---LRREQQERREQRLKREEEEERLEQ 670
E+ +Q K EQEE+ Q+Q +RR++++ EQ ++ ++EE++++
Sbjct: 703 EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 258 bits (659), Expect = 4e-68
Identities = 199/684 (29%), Positives = 381/684 (55%), Gaps = 94/684 (13%)
Query: 420 RREQQLRREQEEERHE------QKHEQERR----EQRLKREQEERRDWLKREEETERHEQ 469
+ ++ LRRE E + H QK E + + +K+ + E RD + R ++ +
Sbjct: 116 QHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAG 175
Query: 470 E---------RRKQQLKRDQEEERRER-WLKLE-------EEERREQQERREQQLRREQE 512
E +K++ R EE +ER L LE +EE +E+ + +++L+ +
Sbjct: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
Query: 513 ERREQRLKRQEEEERLQQR--LRSEQQLRREQEERREQLLKREEEKRLEQERRE--QRLK 568
E+ E +L +E + +L++ L +QQL+ E + ++L + + + E E RL
Sbjct: 236 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295
Query: 569 REQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEE 628
++QEE+ + R+EE+ Q+ ++ QE+ + R + E++ E++ RR++ + E+ E+
Sbjct: 296 QQQEEK----MWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 351
Query: 629 RRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEE 688
RRQ+ + E++E+ R+Q+ E +E++++R+EE ++ RE EE+ EQE E
Sbjct: 352 RRQEEMMWEKEEKMRRQE---EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 408
Query: 689 EQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQW 748
++E+ +E K R E + RQ + R++E R EQEEK R +E ++ W
Sbjct: 409 QEEKRQEEEKIR----------EQEKRQEQEAKMWRQEEKIR---EQEEKIREQEKKM-W 454
Query: 749 QEEERAHRQQQ--EEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQR 806
++EE+ H Q++ EEE+R++ W+ EEK + + + EQ E+ + EE+ R
Sbjct: 455 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWR 514
Query: 807 EQRFLPEEEEK--EQRRRQRREREK---ELQFLEEEEQLQRRERA---QQLQEEEDGLQE 858
++ + E+EEK EQ + R+ EK + + EEE++ +E+ ++ QE+ED +
Sbjct: 515 QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWR 574
Query: 859 DQERRRSQEQ---RRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQR 915
+E+ R QE+ R+++K R E+E KR+ +E++ K+++ ++E+EE++Q
Sbjct: 575 QEEKIREQEEKVWRQEEKIR---EQEEKRQEQ--------EEKMWKQEEKIREQEEKIQE 623
Query: 916 EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLG 975
+E + R EQE + RE+E++ QE+E+ + E+ EK QE +K+Q++EE +
Sbjct: 624 QEEKIR---EQEEKIREQEEMTQEQEEKMGEQEEKMCEQE--------EKMQEQEETMWR 672
Query: 976 EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLR 1035
+E + R E+EKK RE+EE +E+E++++E+ EK QE E+ +++++Q++EE++ R
Sbjct: 673 QEEKIR---EQEKKIREQEEKIREQEEMMQEQEEKMWEQE-EKMCEQEEKMQEQEEKMRR 728
Query: 1036 EEREKRRLQERERQYREEEELQQE 1059
+E ++ E+E + R++EE QE
Sbjct: 729 QE---EKMWEQEVRLRQQEEKMQE 749
Score = 256 bits (655), Expect = 1e-67
Identities = 203/774 (26%), Positives = 398/774 (51%), Gaps = 120/774 (15%)
Query: 434 HEQKHEQERREQRLKREQEERRDWLKREEETERHEQ----------ERRKQQLKRDQEEE 483
H H + +E + + +E+ T+ H Q + +K+++ E
Sbjct: 38 HLPTHPHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPE 97
Query: 484 RRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQE 543
E+ ++ + ++ LRRE E + ++ LQ L Q ++ E
Sbjct: 98 TTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLE 157
Query: 544 ERREQLLKREEEK-----RLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE---QE 595
L+ R + LEQ ++++ +R + L +E + L R E
Sbjct: 158 GEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE 217
Query: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEE-RRQQLLKSEEQEERRQQQLRREQQER 654
E E+ K +E +L + E+ E +L +E + + R +LL ++Q + L +E Q
Sbjct: 218 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 277
Query: 655 REQRLKREEEEERLEQRLKREHEEER-REQELAEEEQEQARERIKSRIPKWQWQLESEAD 713
+L+ + EE L RL ++ EE+ R++E +E +E+ +E+ E +
Sbjct: 278 -SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ------------EEKIR 324
Query: 714 ARQSKVYSRPRKQEGQRRRQEQ----EEKRRRRESELQWQEEERAHRQQQ-----EEEQR 764
++ K+ R+QE + RRQE+ +E++ RR+ E+ W++EE+ RQ++ EE+ R
Sbjct: 325 EQEEKI----REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 380
Query: 765 RDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQR 824
R W+ EEK +++ + +REQ EE++Q E++ +E+ +EQ +
Sbjct: 381 RQEEMMWEKEEKIRELEEKMHEQEKIREQ-------EEKRQEEEKIREQEKRQEQEAKMW 433
Query: 825 REREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKR 884
R+ EK E+EE+++ +E+ QEE+ +QE+ R +E+R++Q+ W+ EE+
Sbjct: 434 RQEEK---IREQEEKIREQEKKMWRQEEKI---HEQEKIREEEKRQEQEEMWRQEEKIHE 487
Query: 885 RRHTLYAKPALQEQ---LRKEQQLLQEEEEELQREEREKRRRQE-----QERQYREEEQL 936
+ K + EQ +RK+++ + +EE++ RE+ EK R QE QE + RE+E++
Sbjct: 488 QEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKI-REQEEKIREQEEKMWRQEEKIREQEEM 546
Query: 937 QQEEEQLLREER---EKRRRQERERQYRKDKKLQQKEEQL------LGEEPEKRRRQE-- 985
+EEE++ +E+ E++R+++ ++ +R+++K++++EE++ + E+ EKR+ QE
Sbjct: 547 WREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606
Query: 986 ----------REKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLR 1035
+E+K +E+EE +E+E+ +RE+ E + QE E E+E+ +
Sbjct: 607 MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQE---------EKMGEQEEKMC 657
Query: 1036 EEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLR 1095
E+ EK + QE E +R+EE+++++E+++ +E E + R++EE+ QE+E+ +
Sbjct: 658 EQEEKMQEQE-ETMWRQEEKIREQEKKI----------REQEEKIREQEEMMQEQEEKMW 706
Query: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQE 1149
E+ EK C +EE++Q++EE++ R+E EK QE+ + R++EE QE
Sbjct: 707 EQEEK--------MCEQEEKMQEQEEKMRRQE-EKMWEQEV--RLRQQEEKMQE 749
Score = 256 bits (655), Expect = 1e-67
Identities = 199/741 (26%), Positives = 398/741 (53%), Gaps = 114/741 (15%)
Query: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208
E+EQ + ++ R+ELE Q L ++ +L + ++ + + + R
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 1209 KRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGREN---EQFRQ-LEDSQLRDRQS- 1263
++ E +++ +K+ A R + K R+ E +R + D +L+++ +
Sbjct: 168 HDSWKFAGELEQA--LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 225
Query: 1264 -QQDLQHLLGEQQERDRE-QERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLL 1321
Q+ LQ + E+ E +E +R +R + ++QL+ E K S + + +
Sbjct: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
Query: 1322 REEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQ 1381
E R Q+ + K +E+ +QE EE K +E+E + +EQ K E+E+
Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEE----------KIQEQEEKIREQEEKIREQEE 335
Query: 1382 RLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRR 1441
++RRQE E + KEE+ R++++ +++ K R +E+ + E++ K R +E+ +
Sbjct: 336 KMRRQE-EMMWEKEEKM----RRQEEMMWEKEEKMRRQEEMM--WEKEEKMRRQEEMM-- 386
Query: 1442 QERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDR 1501
E+E K E E+++ ++ K RE+E+ + +EE+++ QE+ +EQ+ + ++
Sbjct: 387 WEKEEKIRELEEKMHEQE--KIREQEE--KRQEEEKIREQEK-----RQEQEAKMWRQEE 437
Query: 1502 KFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561
K REQE + +E E+K +E+++H Q++ R+ +++RQ+++ +R+EE
Sbjct: 438 KIREQEEKIREQEKKMWRQEEKIHEQEKIRE--------------EEKRQEQEEMWRQEE 483
Query: 1562 QLRQERE--EQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDR 1619
++ ++ E Q+ E++ K R +E+KV RQE+ K E E+++R QE ++ RQE
Sbjct: 484 KIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEE--KIREQEEKIREQE-EKMWRQEE-- 538
Query: 1620 KFREDEQLLQEREEQQLHRQER---DRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLL 1676
K RE E++ REE+++H QE+ + K E+E ++ RQE +++R ++ +R+EE++
Sbjct: 539 KIREQEEMW--REEEKMHEQEKIWEEEKRQEQEDKMWRQE--EKIREQEEKVWRQEEKI- 593
Query: 1677 QEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE 1736
EQ+ +RQE++ K ++E+++R E+E K ++E+++R QE K RE+E++ QE E
Sbjct: 594 ---REQEEKRQEQEEKMWKQEEKIR--EQEEKIQEQEEKIREQE--EKIREQEEMTQEQE 646
Query: 1737 QEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRK 1796
++ ++E K+ E+E+ E+EE R++E+ R+ +E+++R++ E K
Sbjct: 647 EKMGEQEE---KMCEQEEKMQEQEETMWRQEEKIRE--QEKKIREQEE-----------K 690
Query: 1797 FREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEK 1856
RE+E++ QE+EE+ WE+E+ E++E+ QE EK
Sbjct: 691 IREQEEMMQEQEEKM-----------WEQEEKMCEQEEKMQEQE--------------EK 725
Query: 1857 SRREEQELWQEEEQKRRQERE 1877
RR+E+++W++E + R+QE +
Sbjct: 726 MRRQEEKMWEQEVRLRQQEEK 746
Score = 255 bits (652), Expect = 3e-67
Identities = 190/628 (30%), Positives = 365/628 (58%), Gaps = 86/628 (13%)
Query: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREERE----EKRRRQETDRKFREEEQLLQEREE 1350
E EQ + K+ DR +E L +ER+ E R TD + +E+ LQE+
Sbjct: 176 ELEQALSAVATQKKKADRYIEE----LTKERDALSLELYRNTITDEELKEKNAKLQEKL- 230
Query: 1351 QPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQ 1410
Q + ++ + + +EL+ + + K L +Q+L + E L +E Q + + Q+ +
Sbjct: 231 QLVESEKSEIQLNVKELKRKLERAKLLLPQQQL---QAEADHLGKELQSVSAKLQAQVEE 287
Query: 1411 DR--DRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQ 1468
+ +R +++E+++ RQE K +E E+++ QE+E K E+E+++R E+ K R +E+
Sbjct: 288 NELWNRLNQQQEEKMWRQEE--KIQEWEEKI--QEQEEKIREQEEKIR-EQEEKMRRQEE 342
Query: 1469 LLQEREEQQLHRQERDRKFLEEEQQLRRQE-----RDRKFREQELRSQEPERKFLEEEQQ 1523
++ E+EE+ ++E E+E+++RRQE ++ K R QE E E K E E++
Sbjct: 343 MMWEKEEKMRRQEEM---MWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 399
Query: 1524 LHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRL 1583
+H Q++ R EQ+ +RQE + K RE+E+ R+EQ+ ++ K R
Sbjct: 400 MHEQEKIR-----EQEEKRQE---------EEKIREQEK----RQEQEAKMWRQEEKIRE 441
Query: 1584 EEQKVRRQEQERKFMEDEQQLRRQEG--QQQLRQERDRKFREDEQLLQEREEQQLHRQER 1641
+E+K+R EQE+K E+++ QE +++ RQE++ +R++E++ E++++ RQ+
Sbjct: 442 QEEKIR--EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI---HEQEEIWRQKE 496
Query: 1642 DRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRK----FREEE 1697
K E+E ++R+QE E+ R ++ K RE+E+ ++E EE+ R++E+ R+ +REEE
Sbjct: 497 --KMHEQEEKIRKQE-EKVWR--QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551
Query: 1698 ---------QQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRK 1748
++ +RQE+E K ++E+++R QE E+ +R+EE++R EQE+ R+++ +
Sbjct: 552 KMHEQEKIWEEEKRQEQEDKMWRQEEKIREQE-EKVWRQEEKIR---EQEEKRQEQEEKM 607
Query: 1749 ILEEEQLRPERE---EQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQ 1805
+EE++R + E EQ+ + +E++ K RE+E++ QE+EE + E + K E+E+ Q
Sbjct: 608 WKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEE---KMGEQEEKMCEQEEKMQ 664
Query: 1806 EREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELW 1865
E+EE R ++ + E++ ++ EQE+++R++ + EE+ QE+ E++E
Sbjct: 665 EQEETMWRQEE-----KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 719
Query: 1866 QEEEQKRRQERERKLREEHIRRQQKEEQ 1893
QE+E+K R++ E K+ E+ +R +Q+EE+
Sbjct: 720 QEQEEKMRRQ-EEKMWEQEVRLRQQEEK 746
Score = 249 bits (636), Expect = 2e-65
Identities = 194/674 (28%), Positives = 380/674 (56%), Gaps = 86/674 (12%)
Query: 1119 EEEQLLREEREKRRRQELERQYR-------EEEEVQQE--EEQLLREEPEKRRRQELERQ 1169
E+EQ + ++ R+ELE Q ++ E+Q Q ++ E R + R
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 1170 YREEEELQQEEEQLLREEQEKRRQER--ERQYREEEELQRQKRKQRYRDED-QRSDLKWQ 1226
+ + + E+ L +K++ +R E +E + L + + DE+ + + K Q
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
Query: 1227 WEPEKENAVRDNKVYCKGRENEQFRQLEDSQLR--DRQSQQDLQHLLGEQQE-----RDR 1279
EK V K + E R+LE ++L +Q Q + HL E Q + +
Sbjct: 228 ---EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284
Query: 1280 EQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFR 1339
+E W + ++ +EE++ R+E+K + + K QE+++ +RE+ E+ R ++E K R
Sbjct: 285 VEENELWNRLNQQ--QEEKMWRQEEK-IQEWEEKIQEQEEKIREQEEKIREQEE---KMR 338
Query: 1340 EEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQE-----RERKFLK 1394
+E+++ E+EE+ +RRQE +EE++R QE+ E+E+++RRQE +E K +
Sbjct: 339 RQEEMMWEKEEK-MRRQEEMMWEKEEKMRRQEE--MMWEKEEKMRRQEEMMWEKEEKIRE 395
Query: 1395 EEQQLRCQE--REQQLRQDRDRKFREEEQQLSRQER----DRKFREEEQQVRRQE----R 1444
E+++ QE REQ+ ++ + K RE+E++ ++ + + K RE+E+++R QE R
Sbjct: 396 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR 455
Query: 1445 ERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQE----RDRKFLEEEQQLRRQE-- 1498
+ + + E++++R+E R+ +EE R+E+++H QE + K E+E+++R+QE
Sbjct: 456 QEEKIHEQEKIREEEKRQEQEE----MWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEK 511
Query: 1499 ---RDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQER---GQQRRQD 1552
++ K REQE + +E E K +E+++ Q+ + +EE+++ QE+ ++R++
Sbjct: 512 VWRQEEKIREQEEKIREQEEKMWRQEEKIREQE---EMWREEEKMHEQEKIWEEEKRQEQ 568
Query: 1553 RDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ 1612
D+ +R+EE++R++ E+++ RQE ++ EQ+ +RQEQE K + E+++R QE +
Sbjct: 569 EDKMWRQEEKIREQ--EEKVWRQEE----KIREQEEKRQEQEEKMWKQEEKIREQE---E 619
Query: 1613 LRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHD----RDRK 1668
QE++ K RE E+ ++E+EE QE++ K E+E ++ QE + Q + + ++ K
Sbjct: 620 KIQEQEEKIREQEEKIREQEEMT---QEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEK 676
Query: 1669 FREEEQLLQEGEEQQLRRQERDRKFREE---EQQLRRQERERKFLQEEQQLRRQELERKF 1725
RE+E+ ++E +E+++R QE + +EE EQ+ + E+E K ++E+++RRQE E+ +
Sbjct: 677 IREQEKKIRE-QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE-EKMW 734
Query: 1726 REEEQLRQETEQEQ 1739
+E +LRQ+ E+ Q
Sbjct: 735 EQEVRLRQQEEKMQ 748
Score = 249 bits (635), Expect = 2e-65
Identities = 196/723 (27%), Positives = 395/723 (54%), Gaps = 96/723 (13%)
Query: 264 EPQRQRELQEEEEQLRKLERQ--ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321
E +++ Q +E R+LE Q +R ++ + Q L Q ++ E E R+
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 322 REQQERREQQEERREQ-QLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRRE 380
+ + + E+ ++++ +R ++L +E++ E +EE +E+ + +
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
Query: 381 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQ 440
++L+ + + E QL ++ R+ L R + L +QQL+ E + H K E
Sbjct: 228 EKLQLVESEKSEIQLNVKELKRK---------LERAKLLLPQQQLQAEAD---HLGK-EL 274
Query: 441 ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQ 500
+ +L+ + EE W + ++ E K ++EE+ + W EE+ +EQ+
Sbjct: 275 QSVSAKLQAQVEENELWNRLNQQQEE----------KMWRQEEKIQEW----EEKIQEQE 320
Query: 501 ERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEE--RREQLLKREEEKRL 558
E+ +R ++E+ REQ K + +EE + ++ E+++RR++E +E+ ++R+EE
Sbjct: 321 EK----IREQEEKIREQEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKMRRQEEMMW 373
Query: 559 EQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERL-EQEERRE 617
E+E + +R + E+ +++ + EE+ +Q REQEE KR+E E++ EQE+R+E
Sbjct: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE------KRQEEEKIREQEKRQE 427
Query: 618 QRLKREEPEEERRQQLLKSEEQEER--RQQQLRREQQERREQRLKREEEEERLEQRLKRE 675
Q K EE+ R+Q K EQE++ RQ++ EQ++ RE+ ++E+EE ++ E
Sbjct: 428 QEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHE 487
Query: 676 HEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQ 735
EE R++E E++E+ R++ + W+ E + ++ K+ R+QE + RQE+
Sbjct: 488 QEEIWRQKEKMHEQEEKIRKQEEK-----VWRQEEKIREQEEKI----REQEEKMWRQEE 538
Query: 736 EEKRRRRESELQWQEEERAHRQQ---QEEEQRRDFTWQWQAEEKSERGRQRLSARPPLRE 792
+ RE E W+EEE+ H Q+ +EE+++ W+ EEK +RE
Sbjct: 539 ----KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEK-------------IRE 581
Query: 793 QRERQLRAEE--RQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQ 850
Q E+ R EE R+Q E+R +E+E++ +++ + RE+E + E+EE++ RE+ ++++
Sbjct: 582 QEEKVWRQEEKIREQEEKR---QEQEEKMWKQEEKIREQEEKIQEQEEKI--REQEEKIR 636
Query: 851 EEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEE 910
E+E+ QE +E+ QE++ ++ EE+ + + T++ + +E++R++++ ++E+E
Sbjct: 637 EQEEMTQEQEEKMGEQEEKMCEQ-----EEKMQEQEETMWRQ---EEKIREQEKKIREQE 688
Query: 911 EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKE 970
E+++ +E QEQE + E+E+ E+E+ ++E+ EK RRQE E+ + ++ +L+Q+E
Sbjct: 689 EKIREQE---EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE-EKMWEQEVRLRQQE 744
Query: 971 EQL 973
E++
Sbjct: 745 EKM 747
Score = 234 bits (597), Expect = 6e-61
Identities = 185/702 (26%), Positives = 369/702 (52%), Gaps = 101/702 (14%)
Query: 999 EEEQLLREEREKRRRQEWERQYR-------KKDELQQ----EEEQLLREEREKRRLQERE 1047
E+EQ + ++ R+E E Q +K ELQ + + + E E R L R
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISR- 166
Query: 1048 RQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQE-- 1105
+ + E EQ L +++ + R EEL +E + L E E
Sbjct: 167 --LHDSWKFAGELEQALSAVATQKKKAD-----RYIEELTKERDALSLELYRNTITDEEL 219
Query: 1106 RERQCREEEELQ---QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162
+E+ + +E+LQ E+ ++ +E +R+ E + ++++Q E + L +E
Sbjct: 220 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 279
Query: 1163 RQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSD 1222
+ + + EE EL Q Q+ E+ +R+EE++Q + K + ++E R
Sbjct: 280 KLQAQV---EENELWNRLNQ----------QQEEKMWRQEEKIQEWEEKIQEQEEKIR-- 324
Query: 1223 LKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQE 1282
E+E +R+ + E+ R+ E+ + + + ++ E++E+ R QE
Sbjct: 325 -------EQEEKIRE--------QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 369
Query: 1283 RRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEE 1342
W++ ++ +EE + +E+K + ++ ++EK E+EEKR+ +E K RE+E
Sbjct: 370 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI---REQEEKRQEEE---KIREQE 423
Query: 1343 QLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQ 1402
+ R+EQ + ++ K RE+E + +EQ +K +E+++ QE+ R+ K ++Q
Sbjct: 424 K----RQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW 479
Query: 1403 EREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRK 1462
+E+++ + ++ +R++E+ E++ K R++E++V RQE K E+E+++R++ +
Sbjct: 480 RQEEKIHE-QEEIWRQKEKM---HEQEEKIRKQEEKVWRQEE--KIREQEEKIREQEEKM 533
Query: 1463 FREEEQLLQE----REEQQLHRQER---DRKFLEEEQQLRRQERDRKFREQELRSQEPER 1515
+R+EE++ ++ REE+++H QE+ + K E+E ++ RQE K REQE + E
Sbjct: 534 WRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEE--KIREQEEKVWRQEE 591
Query: 1516 KFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDR----KFREEEQLRQEREEQQ 1571
K E+E++ RQ+++ K ++E+++R QE Q ++++ R K RE+E++ QE+EE+
Sbjct: 592 KIREQEEK--RQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKM 649
Query: 1572 LSRQER----DRKFRLEEQKVRRQE-----QERKFMEDEQQLRRQEGQQQLRQERDRKFR 1622
++E+ + K + +E+ + RQE QE+K E E+++R QE ++ QE++ K
Sbjct: 650 GEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQE---EMMQEQEEKMW 706
Query: 1623 EDEQLLQEREEQQLHRQER----DRKFLEEEPQLRRQEREQQ 1660
E E+ + E+EE+ ++E+ + K E+E +LR+QE + Q
Sbjct: 707 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
Score = 220 bits (561), Expect = 9e-57
Identities = 171/631 (27%), Positives = 345/631 (54%), Gaps = 83/631 (13%)
Query: 1340 EEEQLLQEREEQPLRRQER-----------DRKFREEELRHQEQGRKFLEEEQR--LRRQ 1386
E+EQ + ++ LRR+ + + L + + K LE E R + R
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 1387 ERERKFLKEEQQLRCQEREQQLRQDRD-RKFREEEQQLSRQ------------ERDRKFR 1433
KF E +Q Q+ + DR + +E LS + E++ K +
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
Query: 1434 EEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKF---LEE 1490
E+ Q V ++ E + +E + + ER + ++QL E + Q K +EE
Sbjct: 228 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 287
Query: 1491 EQQLRR--QERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQE---- 1544
+ R Q+++ K QE + QE E K E+E+++ Q + K ++E+++RRQE
Sbjct: 288 NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQ--EEKIREQEEKMRRQEEMMW 345
Query: 1545 -------RGQQRRQDRDRKFREEEQLRQEREEQQLSRQ----ERDRKFRLEEQKVRRQEQ 1593
R ++ +++ K R +E++ E+EE+ ++ E++ K R E+K+ QE+
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 405
Query: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLR 1653
R+ E+++Q + +Q+ RQE++ K E+ ++E+EE+ +E+++K +E ++
Sbjct: 406 IRE-QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK---IREQEKKMWRQEEKIH 461
Query: 1654 RQE--REQQLRHDRDRKFREEEQLLQEGE--EQQLRRQERDRKFREEEQQLRRQERERKF 1709
QE RE++ R +++ +R+EE++ ++ E Q+ + E++ K R++E+++ RQ E K
Sbjct: 462 EQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQ--EEKI 519
Query: 1710 LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQER 1769
++E+++R QE E+ +R+EE++R EQE++ R+E K+ E+E++ E++ R+++
Sbjct: 520 REQEEKIREQE-EKMWRQEEKIR---EQEEMWREE--EKMHEQEKI----WEEEKRQEQE 569
Query: 1770 DRKFREEEQLRQE-----REEQQLRSQESDRKFREEEQLRQERE--EQQLRPQQRDGKYR 1822
D+ +R+EE++R++ R+E+++R QE R+ +EE+ +QE + EQ+ + Q+++ K R
Sbjct: 570 DKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIR 629
Query: 1823 WEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE-LWQEEEQKRRQER----- 1876
+EE+++ EQE+ +++ ++ EE+ QE+ +E++E +W++EE+ R QE+
Sbjct: 630 EQEEKIR--EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQ 687
Query: 1877 ERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
E K+RE+ Q++EE+ Q ++ QE K
Sbjct: 688 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 718
Score = 114 bits (284), Expect = 1e-24
Identities = 113/429 (26%), Positives = 211/429 (49%), Gaps = 63/429 (14%)
Query: 1505 EQELRSQEPERKFLEEEQQLHRQQR---QRKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561
EQ+ Q E E E Q+H + Q+ LQ + Q + RD R +
Sbjct: 110 EQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHD 169
Query: 1562 QLRQERE-EQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRK 1620
+ E EQ LS +K ++ + +ER + E L R + +E++ K
Sbjct: 170 SWKFAGELEQALSAVATQKK--KADRYIEELTKERDALSLE--LYRNTITDEELKEKNAK 225
Query: 1621 FREDEQLLQ-EREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG 1679
+E QL++ E+ E QL+ +E RK + L +Q+ + + H +L +
Sbjct: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
Query: 1680 EEQQL----RRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQET 1735
EE +L +Q+ ++ +R+EE + QE E K ++E+++R QE K RE+E+ +
Sbjct: 286 EENELWNRLNQQQEEKMWRQEE---KIQEWEEKIQEQEEKIREQE--EKIREQEEKMRRQ 340
Query: 1736 EQEQLRRQERYRKILEEEQLRPEREEQQLRRQE----RDRKFREEEQLRQEREEQQLRSQ 1791
E+ ++E+ R+ +E++ E+EE+ R++E ++ K R +E++ E+EE + +
Sbjct: 341 EEMMWEKEEKMRR---QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE---KIR 394
Query: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQ------Y 1845
E + K E+E++R++ E++Q +E+++R++ RQ +
Sbjct: 395 ELEEKMHEQEKIREQEEKRQ---------------------EEEKIREQEKRQEQEAKMW 433
Query: 1846 RAEEQFATQ-EKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKE----EQRHRQVGE 1900
R EE+ Q EK R +E+++W++EE+ QE K+REE R++Q+E E++ + E
Sbjct: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQE---KIREEEKRQEQEEMWRQEEKIHEQEE 490
Query: 1901 IKSQEGKGH 1909
I Q+ K H
Sbjct: 491 IWRQKEKMH 499
Score = 111 bits (277), Expect = 8e-24
Identities = 101/385 (26%), Positives = 199/385 (51%), Gaps = 40/385 (10%)
Query: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ---LRQ 1615
E+EQ + ++ L R+ + + ++ E + + +++ EG+ + R
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 1616 ERDRKFR-EDEQLL------QEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRK 1668
KF E EQ L +++ ++ + ++R L E L R + +++ K
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLE--LYRNTITDEELKEKNAK 225
Query: 1669 FREEEQLLQ-EGEEQQLRRQERDRKFREEEQQLRRQE--RERKFLQEEQQLRRQELERKF 1725
+E+ QL++ E E QL +E RK + L +Q+ E L +E Q +L+ +
Sbjct: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
Query: 1726 REEE---QLRQETEQEQLRRQERYRKILEEEQLRPER-EEQQLRRQERDRKFREEEQLRQ 1781
E E +L Q+ E++ R++E+ ++ E+ Q + E+ EQ+ + +E++ K R +E++
Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345
Query: 1782 EREEQQLRSQE----SDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQL--QLEEQ-- 1833
E+EE+ R +E + K R +E++ E+EE+ R ++ WE+E+ +LEE+
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM----MWEKEEKIRELEEKMH 401
Query: 1834 EQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQ-----ERERKL--REEHIR 1886
EQ +E++ + + EE+ QEK + +E ++W++EE+ R Q E+E+K+ +EE I
Sbjct: 402 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 461
Query: 1887 RQQK--EEQRHRQVGEIKSQEGKGH 1909
Q+K EE++ ++ E+ QE K H
Sbjct: 462 EQEKIREEEKRQEQEEMWRQEEKIH 486
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 282 bits (722), Expect = 2e-75
Identities = 400/1858 (21%), Positives = 840/1858 (45%), Gaps = 234/1858 (12%)
Query: 225 EKQQQRRERQDRVFQEEEEKEWRKRE--TVLRKEEEKLQEEEPQRQRELQEEEEQLRKLE 282
E QQR +RQ+ + + +E +E T+L E+E LQE+ +R +EL E+ + L E
Sbjct: 282 ETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQEL-EKIKDLHMAE 340
Query: 283 RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE 342
+ +L + ++ + ++L +++ + E + Q E E +E Q R +Q+ +
Sbjct: 341 KTKLITQLRDAKNLIEQLEQDKGM---VIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQ 397
Query: 343 QEERREQQLRREQ---EEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQ 399
EE REQ+ + E+ EE + ++ EE RR+ + ++Q++ ++ E+++ +Q
Sbjct: 398 GEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQ 457
Query: 400 QLRREQQ-------LRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQE 452
+L R +Q E+Q+ + Q+L ++ R+EQE + Q E+E +EQ ++
Sbjct: 458 ELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEK 517
Query: 453 ERRDWLKREEETERHE----QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLR 508
+ ++LK +E E+ E +E Q+ E E + R L+ E E R + E L
Sbjct: 518 SQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLE 577
Query: 509 REQEERREQ-----------RLKRQEEEERLQQRLRSEQQLRREQEE----RREQLLKRE 553
+ +E + Q + K +E + ++ ++E + + Q++ + Q+LK++
Sbjct: 578 KSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQ 637
Query: 554 EEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQR-LKREEVERLEQ 612
+ +E +L+ + E+ ++ LLK +E Q ++ E+ LE+ +K+ E+E L
Sbjct: 638 YQTEME------KLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSS 691
Query: 613 E--ERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEE-ERLE 669
E E + R K EE + Q K +++ E + + + Q++ + +K E +R E
Sbjct: 692 ELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTE 751
Query: 670 QRLK----------REHEEERREQELAEEEQEQARERIKSRIPKWQWQLE-----SEADA 714
+ LK +E ++ +E + E E +R + + + +L+ A
Sbjct: 752 KALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATH 811
Query: 715 RQSKVYSRPRKQEGQRRRQEQEEK----RRRRESELQWQE---EERAHR------QQQEE 761
Q+K Y Q Q+ + E+ ++ E E Q ++ E AH+ QQ E
Sbjct: 812 EQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLE 871
Query: 762 EQRRDFTWQWQA-----EEKSERG-RQRLSARPPLREQRERQLRAEERQQREQRFLPEEE 815
+Q + + ++ E K E G +++ + L E+ L+ E Q++E L ++
Sbjct: 872 KQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKL 931
Query: 816 EKEQRRRQRREREKELQFLEEEEQLQR-RERAQQLQE--------EEDGLQEDQERRRSQ 866
++ E E +F +E+++++ +++A+++QE +E L+++ E +
Sbjct: 932 SAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALE 991
Query: 867 EQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREE--------R 918
++++++ ++ E + + + E +KEQ E E+ R E
Sbjct: 992 LSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQI---ESLTEVHRRELNDVISIWE 1048
Query: 919 EKRRRQEQERQYREEEQLQQEEEQLL------------REEREKRRRQERERQYRKDKKL 966
+K +Q +E Q E QLQ++E+++ +EE K +E ++D L
Sbjct: 1049 KKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTL 1108
Query: 967 QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
+ +EQL + + E K + L++ E L + +E QE Q + L
Sbjct: 1109 NELQEQLKQKSAHVNSLAQDETKLKAH--LEKLEVDLNKSLKENTFLQE---QLVELKML 1163
Query: 1027 QQEEEQLLREEREKRRLQERERQY----REEEELQQEEEQLLGEERETRRRQELERQYRK 1082
+E+++ + E K + + E Q E+ E++ L ++ +L+ +K
Sbjct: 1164 AEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKK 1223
Query: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE-----EREKRRRQELE 1137
E L + + L + R + + +E LL + E E + RQ E
Sbjct: 1224 TEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTE 1283
Query: 1138 RQYREEEEVQQEEEQLLREEPE-KRRRQELERQYREEEELQQE--EEQLLREEQEKRRQE 1194
Q QQ QL +E + K + ++E E+E LQ+E +Q E+E +
Sbjct: 1284 EQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQ 1343
Query: 1195 RERQYRE--------EEELQRQKRKQRYRDEDQRSDLKWQWE-----PEKENAVRDNKVY 1241
+++ E +EEL ++K+ + Q +DL Q + EKE A+ +
Sbjct: 1344 LKKELSENINAVTLMKEEL-KEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQ 1402
Query: 1242 CKGRENEQFRQLEDSQLR-DRQSQQDLQHLLGEQQERDREQERRRWQQRDR-HFPEEEQL 1299
+ E Q++D + D S++ + L +Q D + W+++ + F + +
Sbjct: 1403 YDEEKCELLDQVQDLSFKVDTLSKEKISAL---EQVDDWSNKFSEWKKKAQSRFTQHQNT 1459
Query: 1300 EREEQKEAKRRDRKSQEEKQ---LLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQ 1356
+E Q + + + +++ E+ + LL+EE +++ +R + + E+++ E++E L +
Sbjct: 1460 VKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETE 1519
Query: 1357 ERDRKFREEELR-HQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRK 1415
+ + R EL H Q +E + + ++K ++ ++ ++ + Q+L +++D +
Sbjct: 1520 LKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNR 1579
Query: 1416 FREEEQQL---------SRQERDRKFREEEQ---QVRRQERERKFLEEE---------QQ 1454
+E E+++ + E + K +E E V+ +E E K LE+ +
Sbjct: 1580 VKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAE 1639
Query: 1455 LRQERHRKFRE-EEQLLQEREEQQLHRQERDRKFLEE-EQQLRRQERDRKFREQELRSQE 1512
L+++ +K ++QLL + EE++ ++ L E +L+ +ER+ E++L+S E
Sbjct: 1640 LKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVE 1699
Query: 1513 PERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDR----DRKFREEEQLRQ--- 1565
+ E + R + E+++ Q Q+ +++ R E+E+L Q
Sbjct: 1700 SSQS---ETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVG 1756
Query: 1566 -EREEQQLSR-----QERDRKFRLEEQKVRRQEQERKF--MEDE-------------QQL 1604
E+EE S Q ++R +LE + ++ E + +++E Q +
Sbjct: 1757 QEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHV 1816
Query: 1605 RRQEGQQ--QLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLR 1662
++ G+ Q +Q + F + ++ LQE+E L Q ++K E + L RQ+ ++
Sbjct: 1817 EKEGGKNNIQAKQNLENVFDDVQKTLQEKE---LTCQILEQKIKELDSCLVRQKEVHRV- 1872
Query: 1663 HDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQE-- 1720
E E+L + E+ Q +Q R E + +E+ + L + + L E
Sbjct: 1873 --------EMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQ 1924
Query: 1721 ---LERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEE 1777
LE K E+ +Q+ +E +R Q+ R + +E Q +E ++ ++E D++ EE
Sbjct: 1925 HNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQ-----QELEILKKEYDQE--REE 1977
Query: 1778 QLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRL 1837
+++QE+E+ +L+ + ++ E + ++EQ+L ++ + +E + +L E Q
Sbjct: 1978 KIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEE 2037
Query: 1838 RQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRR--QQKEEQ 1893
+ ++ AE+ + ++R E+ L EE+ + R+ + + E +++ QQK EQ
Sbjct: 2038 TNQLLKKI-AEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQ 2094
Score = 270 bits (691), Expect = 8e-72
Identities = 421/1939 (21%), Positives = 854/1939 (44%), Gaps = 277/1939 (14%)
Query: 136 RRRQKRQEQERELAEGEEQSEKQE-RLEQRDRQRRDEELWRQRQEWQEREERRAEE---- 190
++R KRQE + + QS K++ L +++ E+L + QE ++ ++ E
Sbjct: 285 QQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKL 344
Query: 191 -----------EQLQSCKG----------HETEEFPDEE--QLRRRELLELRRKGREEKQ 227
EQL+ KG HET E +EE QLR R + ++ +G E ++
Sbjct: 345 ITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSR-IKQMTTQGEELRE 403
Query: 228 QQRRERQDRVFQEEEEKEWRKRETVLRKEE--EKLQEEEPQRQRELQEEEEQLRKLERQE 285
Q +E+ +R EE EK T + EE KL+ E ++ + +++ E+ R +QE
Sbjct: 404 Q--KEKSERAAFEELEKAL---STAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQE 458
Query: 286 LRRERQE--------EEQQQQRLRR--EQQLRRKQEEERREQQEERREQQERREQQEERR 335
L R +QE E+Q +L++ E++L RK++E ++ Q RE QE+ + E+
Sbjct: 459 LSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKS 518
Query: 336 EQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQL 395
+ + + +E+ +Q+ +E E +++ + E E + R+ L++E + R + L E L
Sbjct: 519 QSEYLKISQEKEQQESLALEELELQKKAILTESENKLRD--LQQEAETYRTRILELESSL 576
Query: 396 RREQQLRREQ------QLRREQQLRREQQLRREQQLRREQEEERHEQ-----------KH 438
+ Q + Q L E+ ++ ++ + E E +H+Q K
Sbjct: 577 EKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQ 636
Query: 439 EQERREQRLKREQEERRDWLKREEET--ERHEQERRKQQLKRDQEEERRERWLKLEEEER 496
+ + ++L+ + E+ ++ L +++E + H +E ++ L++ ++ L E E
Sbjct: 637 QYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEV 696
Query: 497 REQQERREQQLR--REQEERREQRL--KRQEEEERLQQRLRS-----EQQLRREQEERRE 547
+ + + E++L ++Q ++ +Q L K E++ QQ++ S E ++R ++ ++
Sbjct: 697 LKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKD 756
Query: 548 Q-----LLKREEEKRLEQ-----ERREQRLKREQEERRDQLLKREEERRQQRLKREQEER 597
Q LL +E +K L++ E E +KR + E + K + + Q EQ +
Sbjct: 757 QINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKA 816
Query: 598 LEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRRE---QQER 654
E++L + + + L+ E R K+ E +++ + + + + Q L ++ Q
Sbjct: 817 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSE 876
Query: 655 REQRLK--REEEEERLEQRLKREHEEERREQELAEEEQE--QARERIKSRIPKWQWQLES 710
EQ++K + E +LE K E+E+ +Q L E+E Q RE K I +L +
Sbjct: 877 MEQKVKSLTQVYESKLEDGNK---EQEQTKQILVEKENMILQMREGQKKEIEILTQKLSA 933
Query: 711 EADA-------RQSKVYSRPRKQE--GQRRRQEQEEKRRR---RESELQWQEEERAHRQQ 758
+ D+ ++K ++ +K E Q+ ++ QE +++ +E++L+ + E A
Sbjct: 934 KEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELS 993
Query: 759 QEEEQ---------------------RRDFTWQWQAEEKSERGRQRLSARPPLREQRERQ 797
Q+E+Q R + + Q E +E R+ L+ + E++ Q
Sbjct: 994 QKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQ 1053
Query: 798 LRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQ 857
+AEE Q+ + L E+E++ +Q K L F E+E++ + + +E+G++
Sbjct: 1054 -QAEELQEIHEIQLQEKEQEVAELKQ-----KILLFGCEKEEMNK----EITWLKEEGVK 1103
Query: 858 EDQERRRSQEQRRDQKWRWQ--LEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQR 915
+D QEQ + + ++E K + H + L + L KE LQE+ EL+
Sbjct: 1104 QDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSL-KENTFLQEQLVELKM 1162
Query: 916 -EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRR--QERERQYRK---------- 962
E +KR+ E + + + EE Q L+ EK + +++ +++K
Sbjct: 1163 LAEEDKRKVSELTSKLKTTD----EEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLD 1218
Query: 963 ------DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR----EEREKRR 1012
+ L+ K +L+ K + + + +E L++ E E +
Sbjct: 1219 ICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQL 1278
Query: 1013 RQEWERQYRKKDELQQEEEQLLREEREKRRLQ-ERERQYREEEELQQEEEQLLGEERETR 1071
RQ E Q QQ QL +E + + ++ + E E+E LQ+E G +++
Sbjct: 1279 RQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEG----GNQQQAA 1334
Query: 1072 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131
+E K+E + L +E K ++ E ++ +L + + + ++
Sbjct: 1335 SEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEA 1394
Query: 1132 RRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR-EEQEK 1190
L +QY EE+ ++ Q L + + ++++ L+Q ++ + E +K
Sbjct: 1395 AISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKI-------SALEQVDDWSNKFSEWKK 1447
Query: 1191 RRQERERQYREE-EELQRQ---KRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVY--CKG 1244
+ Q R Q++ +ELQ Q K K+ Y ++Q + L KE + NK + KG
Sbjct: 1448 KAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLL-------KEELDQQNKRFDCLKG 1500
Query: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304
++ED + + + + +L+ L Q R E E D + ++E +
Sbjct: 1501 -------EMEDDKSKMEKKESNLETELKSQTARIMELE-------DHITQKTIEIESLNE 1546
Query: 1305 KEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFRE 1364
+K E K+L+++ + + +E D + +E E+ + E Q + + + + ++
Sbjct: 1547 VLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQ-VYSMKAELETKK 1605
Query: 1365 EELRHQEQGRKFLEEEQRL--RRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQ 1422
+EL H K EEE + R E E E + + +++ +++ + E+E+Q
Sbjct: 1606 KELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQ 1665
Query: 1423 LSR------QERDRKFREEEQQVRRQERERKFLEEEQQ--LRQERHRK----FREEEQLL 1470
+ E + K +E E++V E + K +E Q L R K + E+E+
Sbjct: 1666 YKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEAD 1725
Query: 1471 QEREEQQLHRQE---RDRKFLEEEQQLRR--QERDRKFREQ-ELRSQEPER--KFLEEEQ 1522
+ Q+ + ++ R E+E+ L+R QE++ E+R Q ER K E
Sbjct: 1726 SQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEA 1785
Query: 1523 QLHRQQRQRKFLQEEQQLRRQERG-----QQRRQDRDRKFREEEQLRQEREEQQLSRQER 1577
+ H Q LQEE + + ++ ++ + ++ L ++ Q + QE+
Sbjct: 1786 KQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEK 1845
Query: 1578 DRKFRLEEQKVRR------QEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQER 1631
+ ++ EQK++ +++E +E E+ + E Q L+Q R + +LL+E
Sbjct: 1846 ELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGR--NKPTELLEEN 1903
Query: 1632 EEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDR 1691
E E+ + L + L E + +D + K E+ Q+ ++ +R Q+ R
Sbjct: 1904 TE------EKSKSHLVQPKLLSNMEAQ---HNDLEFKLAGAEREKQKLGKEIVRLQKDLR 1954
Query: 1692 KFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILE 1751
R+E QQ E + L++E R+E ++ +E+ +L+ + +QL R+ + +
Sbjct: 1955 MLRKEHQQ------ELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQK 2008
Query: 1752 EEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESD--RKFREEEQLRQEREE 1809
E++L +E + QE + + E Q + +++ ++ D R + E++ REE
Sbjct: 2009 EQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREE 2068
Query: 1810 QQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEE 1869
+ + + Q QLEE +++ +Q+ +++ T EL +
Sbjct: 2069 EMTA--------KVRDLQTQLEELQKKYQQKLEQEENPGNDNVT-------IMELQTQLA 2113
Query: 1870 QKRRQERERKLREEHIRRQ 1888
QK + KL+E+ R Q
Sbjct: 2114 QKTTLISDSKLKEQEFREQ 2132
Score = 239 bits (609), Expect = 2e-62
Identities = 373/1886 (19%), Positives = 805/1886 (42%), Gaps = 224/1886 (11%)
Query: 208 EQLRR--RELLELRRKGRE-----EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKL 260
++LRR R L R K E + Q+ +++ + + ++K R R LR+E +
Sbjct: 141 QRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLR-RIAELREELQMD 199
Query: 261 QEEEPQRQRE----LQEEEEQLRKLERQE--LRRERQEEEQQQQRLRREQQLRRKQEEER 314
Q+ + Q E L+E+++ + L+ Q L++ + L+ QL + E
Sbjct: 200 QQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFT 259
Query: 315 REQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE--EERREQQLRREQEEER 372
+E+ E + + + + L+ ++ +R+E L+R +E + +EQ E+E
Sbjct: 260 KEENPESDGEPVVEDGTSVKTLETLQ-QRVKRQENLLKRCKETIQSHKEQCTLLTSEKEA 318
Query: 373 REQQL-RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEE 431
++QL R Q+L + + L ++ + QLR + L + + + + ++ E E
Sbjct: 319 LQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLE 378
Query: 432 ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKL 491
+ E+ + R +++ + EE R+ ++E++ER E ++ L Q+ E R LK
Sbjct: 379 MKEEEIAQLRSRIKQMTTQGEELRE---QKEKSERAAFEELEKALSTAQKTEEARRKLKA 435
Query: 492 EEEER--------REQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQE 543
E +E+ E++ +Q+L R ++E + K EE+ Q+L ++ R+EQE
Sbjct: 436 EMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQE 495
Query: 544 -----ERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERL 598
+ RE+ + + + LE+ + E +++E+++ L E E +++ + E E +L
Sbjct: 496 LTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKL 555
Query: 599 EQRLKREEVER---LEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655
+ E R LE E E+ L+ + + + L++E+ + ++ + E+ +
Sbjct: 556 RDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTE 615
Query: 656 EQRLKREEEEERLE--QRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEAD 713
+ LK +++ E Q LK++++ E ++L E+ +++ +K + +Q +E +
Sbjct: 616 LESLKHQQDALWTEKLQVLKQQYQTEM--EKLREKCEQEKETLLKDKEIIFQAHIEEMNE 673
Query: 714 ARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQA 773
K+ + + E + K R + E +++ + +QE E + D
Sbjct: 674 KTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMD------- 726
Query: 774 EEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQF 833
E+K+ +Q S +R +A + Q + L +E +K + Q E
Sbjct: 727 EQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADI 786
Query: 834 LEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKP 893
E +LQ+ + + +Q + ++ + Q+ LE ER L K
Sbjct: 787 KRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETER-----ILLTKQ 841
Query: 894 ALQEQLRKE-------------QQLLQE-EEEELQREEREKRRRQEQERQYREEEQLQQE 939
+ + +K+ Q L+Q+ E++ + E++ K Q E + + + Q++
Sbjct: 842 VAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQ 901
Query: 940 EEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQE 999
+Q+L E+E Q RE Q ++ + L QK E+ +E E K++ +E+ ++
Sbjct: 902 TKQIL-VEKENMILQMREGQKKEIEILTQKLSAK--EDSIHILNEEYETKFKNQEKKMEK 958
Query: 1000 EEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREE------ 1053
+Q +E +E +++ +++ + K EL+ +L ++E++ Q
Sbjct: 959 VKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAV 1018
Query: 1054 EELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE- 1112
L+ +++ + E RR+ + E++L Q+ E+L +E + + QE+E++ E
Sbjct: 1019 SRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEEL--QEIHEIQLQEKEQEVAEL 1076
Query: 1113 ---------EEELQQEEEQLLREEREKRRR--QELERQYREEE---EVQQEEEQLLREEP 1158
E+E +E L+EE K+ EL+ Q +++ ++E L+
Sbjct: 1077 KQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHL 1136
Query: 1159 EKRRRQELERQYREEEELQQE--EEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRD 1216
EK +L + +E LQ++ E ++L EE +++ E + + +E + + +
Sbjct: 1137 EKLE-VDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKS 1195
Query: 1217 EDQRSDLKWQWEPEKENAVRDNKVYCKGRE------------------NEQFRQLEDSQL 1258
D +++ E + CK E N ++ Q
Sbjct: 1196 NKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQH 1255
Query: 1259 RDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEK 1318
R + ++ L E + + + +Q + ++ + E+KE + + K+ E
Sbjct: 1256 RTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIES 1315
Query: 1319 QLLREEREEKRRRQETDRKFREEEQLLQEREEQP--------LRRQERDRKFREEELRHQ 1370
+ +E +K + +E + Q ++E ++ + +++K L Q
Sbjct: 1316 LVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQ 1375
Query: 1371 EQGRKF-LEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREE---EQQLSRQ 1426
L+ L +E L+++ +E+ + L Q +D F+ + ++++S
Sbjct: 1376 LTDLNVQLQNSISLSEKEAAISSLRKQYD---EEKCELLDQVQDLSFKVDTLSKEKISAL 1432
Query: 1427 ER----DRKFRE--EEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHR 1480
E+ KF E ++ Q R + + E + QL + + ++EQ+ +EE
Sbjct: 1433 EQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQN 1492
Query: 1481 QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEE-----------QQLHRQQR 1529
+ D E E + E+ E EL+SQ LE+ ++ +
Sbjct: 1493 KRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYN 1552
Query: 1530 QRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQ--LRQEREEQQLSRQERDRKFRLEEQK 1587
Q+K ++ ++ +++ + Q+ +++D + +E E+ L E + + + +K LE
Sbjct: 1553 QQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVN 1612
Query: 1588 --VRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFRE-DEQLLQEREEQQ--------- 1635
V+ +E+E K +ED + +L+++ ++K +QLL + EE++
Sbjct: 1613 LSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTES 1672
Query: 1636 --------LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRK----FREEEQLLQEGEEQQ 1683
L +ER+ LEE+ + + + L R K + E+E+ +G Q+
Sbjct: 1673 HLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQK 1732
Query: 1684 LRRQE---RDRKFREEEQQLRR--QERER--------KFLQEEQQLRRQELERKFREEEQ 1730
++ R E+E+ L+R QE+E + +E+ ++ + E K E++
Sbjct: 1733 TYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQS 1792
Query: 1731 LRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQERE------ 1784
+ ++E + ++Y I+ + + + +Q + F + ++ QE+E
Sbjct: 1793 MIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQIL 1852
Query: 1785 EQQLRSQESDRKFREEEQLRQEREE-----QQLRP-QQRDGKYRWEE--EQLQLEEQEQR 1836
EQ+++ +S R++E R E EE ++L+ QQ DG+ + E E+ E+ +
Sbjct: 1853 EQKIKELDSCL-VRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSH 1911
Query: 1837 LRQ---------------------ERDRQYRAEEQFATQEKSRREEQELWQEEEQKRR-- 1873
L Q ER++Q +E Q+ R +E QE E ++
Sbjct: 1912 LVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEY 1971
Query: 1874 -QERERKLREEHIRRQQKEEQRHRQV 1898
QERE K+++E + K +Q+
Sbjct: 1972 DQEREEKIKQEQEDLELKHNSTLKQL 1997
Score = 214 bits (546), Expect = 5e-55
Identities = 313/1618 (19%), Positives = 700/1618 (43%), Gaps = 246/1618 (15%)
Query: 500 QERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLE 559
+E+ Q+LRR + R K E Q R +++L+ + +++ L+R E R E
Sbjct: 136 KEQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLRRIAELREE 195
Query: 560 QERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR-----EEVERLEQ-E 613
+ +Q K QEE L EE+ + + + Q L+QRL+ + ++ L Q E
Sbjct: 196 LQMDQQAKKHLQEEFDASL---EEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLE 252
Query: 614 ERREQRLKREEPEEERRQ--------QLLKSEEQEERRQQQLRREQQE----RREQRLKR 661
+ E K E PE + + L++ +Q +RQ+ L + +E +EQ
Sbjct: 253 PQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLL 312
Query: 662 EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYS 721
E+E L+++L +E + ++L E+ + +++ L + + + V +
Sbjct: 313 TSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAK-----NLIEQLEQDKGMVIA 367
Query: 722 RPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGR 781
++Q + ++EE + R Q + R+Q+E+ +R F + E+ +
Sbjct: 368 ETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFE---ELEKALSTAQ 424
Query: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEE---------------EKEQRRRQRRE 826
+ AR L+ + + Q++ E+ E+R ++E +EQ + ++
Sbjct: 425 KTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKL 484
Query: 827 REKELQFLEEE--EQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKR 884
EKEL E+E ++LQ RER Q ++ + L++ Q Q ++Q+ LEE +
Sbjct: 485 HEKELARKEQELTKKLQTREREFQ-EQMKVALEKSQSEYLKISQEKEQQESLALEELELQ 543
Query: 885 RRHTLYAKPALQEQLRKEQQLLQ----EEEEELQREEREKRRRQEQERQYREEEQLQQEE 940
++ L L++E + + E E L++ +E + + + + E E+ + +
Sbjct: 544 KKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNK 603
Query: 941 EQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEE 1000
E + E+ K + + Q L ++ Q+L ++ + + REK +E+E L +++
Sbjct: 604 EITVMVEKHKTELESLKHQ---QDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDK 660
Query: 1001 EQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEE 1060
E + + E+ + E+ K+ EL+ +L + + +L+E +++ + ++E
Sbjct: 661 EIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQE 720
Query: 1061 EQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP-------EKRRRQERERQC--- 1110
+ +E++ +Q+++ ++ E Q E+ L+++ ++R + +E Q
Sbjct: 721 LEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVE 780
Query: 1111 -------REEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEK--- 1160
R E ELQQ +L + + E + Y EE++ Q +++LL E E+
Sbjct: 781 NLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAY--EEQLAQLQQKLLDLETERILL 838
Query: 1161 -RRRQELERQYRE---EEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRD 1216
++ E+E Q ++ E + + + Q L ++ EK+ E E++ + ++ K + ++
Sbjct: 839 TKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKE 898
Query: 1217 EDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE 1276
++Q + EKEN + + +G++ E + + +++D H+L E+ E
Sbjct: 899 QEQTKQIL----VEKENMILQMR---EGQKKEI-----EILTQKLSAKEDSIHILNEEYE 946
Query: 1277 RDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDR 1336
+ + ++ ++ +++ E +E + K D++++ +K+L E ++ ++ +
Sbjct: 947 TKFKNQEKKMEK-----VKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNA 1001
Query: 1337 KFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEE-----EQRLRRQERERK 1391
K E Q + R E ++K + E L E R+ L + E++L +Q E
Sbjct: 1002 KMLEMAQANSAGISDAVSRLETNQKEQIESLT--EVHRRELNDVISIWEKKLNQQAEE-- 1057
Query: 1392 FLKEEQQLRCQEREQQLRQDRDR--KFREEEQQLSRQ---------ERDRKFREEEQQVR 1440
L+E +++ QE+EQ++ + + + F E+++++++ ++D E ++Q++
Sbjct: 1058 -LQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLK 1116
Query: 1441 RQ--------ERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQ 1492
++ + E K ++L + ++ +E L ++ E ++ +E RK E
Sbjct: 1117 QKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTS 1176
Query: 1493 QLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRR-- 1550
+L+ D +F+ + S E K LE++ ++ + +Q + ++ E + +
Sbjct: 1177 KLKTT--DEEFQSLK-SSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTN 1233
Query: 1551 --------------------QDRDRKFRE------------EEQLRQEREEQQ---LSRQ 1575
Q R K +E E QLRQ EEQ +S Q
Sbjct: 1234 ELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQ 1293
Query: 1576 ERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEG---QQ----------QLRQERDRKFR 1622
+ + +E +++ + + + + E++ ++EG QQ QL++E
Sbjct: 1294 QATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENIN 1353
Query: 1623 EDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQ----EREQQLRHDRDRKFREEEQLLQE 1678
+ +E +E+++ ++ + QL+ E+E + R + E+ +LL +
Sbjct: 1354 AVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQ 1413
Query: 1679 GEEQQLRRQERDR--------------KFRE----EEQQLRRQERERKFLQEEQQLRRQE 1720
++ + + KF E + + + + K LQ + +L+ +E
Sbjct: 1414 VQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKE 1473
Query: 1721 LERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFR------ 1774
K + L++E +Q+ +R + + +E+++ + E++E L + + + R
Sbjct: 1474 AYEKDEQINLLKEELDQQN-KRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELED 1532
Query: 1775 -------------------------EEEQLRQEREEQQLRSQESDRKFREEEQ--LRQER 1807
E ++L Q+ + Q +E D + +E E+ L E
Sbjct: 1533 HITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLEN 1592
Query: 1808 EEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQEL--- 1864
+ ++ + K E L ++ +E+ L+ DR +E E R+ EQ++
Sbjct: 1593 QVYSMKAELETKKKELEHVNLSVKSKEEELKALEDR-LESESAAKLAELKRKAEQKIAAI 1651
Query: 1865 -------WQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEP 1915
+E+E++ ++ E L E + + Q++E + H ++KS E L+ P
Sbjct: 1652 KKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVP 1709
Score = 208 bits (529), Expect = 5e-53
Identities = 350/1701 (20%), Positives = 737/1701 (43%), Gaps = 212/1701 (12%)
Query: 43 AVLRRPHDPKTVDLILELLDLDSNGRVDFNEFLLFIFKVAQACYYALGQ------ATGLD 96
A L++ H+ + EL +F E + + +Q+ Y + Q + L+
Sbjct: 479 AKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALE 538
Query: 97 E---EKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPG-QRRRQKRQEQERELA--- 149
E +K+A E+ L+D +QE + R R LE E ++ Q+ + Q ++LA
Sbjct: 539 ELELQKKAILTESENKLRDLQQEAETY----RTRILELESSLEKSLQENKNQSKDLAVHL 594
Query: 150 EGEEQSEKQE--------RLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHET 201
E E+ +E + E + + + LW ++ + +++ + E+ + C+ +
Sbjct: 595 EAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKE 654
Query: 202 EEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWR----KRETVLRKEE 257
D+E + + + E+ K E+ ++ E + + E + R + +VL+ +
Sbjct: 655 TLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQT 714
Query: 258 EKLQEE-----EPQRQRELQEEEEQLRKLERQELRRERQEEEQ--QQQRLRREQQLRRKQ 310
+K+++E + Q+ Q+ + +++ E R E+ ++Q Q + L +E+ K+
Sbjct: 715 DKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKE 774
Query: 311 EEERREQQEERREQQERREQQEERR------EQQLRREQEERREQQLRREQE-----EER 359
+ E E ++ E QQ + Q EQ + E+QL + Q+ E
Sbjct: 775 HQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETE 834
Query: 360 REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRR-----EQQLRREQQLRREQQLR 414
R ++ E E +++ + E + Q QQL + EQ+++ Q+ +
Sbjct: 835 RILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLED 894
Query: 415 REQQLRREQQLRREQE----EERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE 470
++ + +Q+ E+E + R QK E E Q+L +E+ L E ET+ QE
Sbjct: 895 GNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLS-AKEDSIHILNEEYETKFKNQE 953
Query: 471 RRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERR---EQRLKRQEEEER 527
++ +++K+ +E + KL ++E + ++E L Q+E++ + Q
Sbjct: 954 KKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAG 1013
Query: 528 LQQRLRSEQQLRREQEERREQLLKRE-------EEKRLEQERRE-------QRLKREQE- 572
+ + + ++EQ E ++ +RE EK+L Q+ E Q ++EQE
Sbjct: 1014 ISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEV 1073
Query: 573 ---ERRDQLLKREEERRQQRLKREQEERLEQRLKREEV-ERLEQEERREQRLKREEPE-- 626
+++ L E+E + + +EE ++Q E+ E+L+Q+ L ++E +
Sbjct: 1074 AELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLK 1133
Query: 627 ---EERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLE------QRLKREHE 677
E+ L KS ++ Q+QL + E + K E +L+ Q LK HE
Sbjct: 1134 AHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHE 1193
Query: 678 EERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEG---QRRRQE 734
+ + E E ++ E + ++ + E+ +A+ +++ + + R
Sbjct: 1194 KSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHC 1253
Query: 735 QEEKRRRRESEL----QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPL 790
Q + +E+ L E E RQ EE+ + ++Q + E+ Q S + +
Sbjct: 1254 QHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADI 1313
Query: 791 RE-QRERQLRAEERQQREQRFLPEEEEKEQRRRQRRE------------REKELQFLEEE 837
E++ +E ++Q +E Q +++ E +EK+++
Sbjct: 1314 ESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLS 1373
Query: 838 EQLQ----RRERAQQLQEEEDGL-----QEDQERRRSQEQRRDQKWRWQLEEERK----- 883
+QL + + + L E+E + Q D+E+ +Q +D ++ + K
Sbjct: 1374 KQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALE 1433
Query: 884 -----RRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQ 938
+ + + K A Q + + Q ++E + +L+ + +E + EQ +EE Q
Sbjct: 1434 QVDDWSNKFSEWKKKA-QSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQN 1492
Query: 939 EEEQLLREERE--KRRRQERERQYRKDKKLQ-----QKEEQLLGEEPEKRRRQEREKKYR 991
+ L+ E E K + +++E + K Q + E+ + + E E K Y
Sbjct: 1493 KRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYN 1552
Query: 992 EEEELQQEE-------EQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ 1044
++++++ +E Q L EE++ R ++ E+ ++++ + +L E +K+ L+
Sbjct: 1553 QQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAEL---ETKKKELE 1609
Query: 1045 ERERQYR-EEEELQQEEEQLLGEE----RETRRRQELERQYRKEEELQQEEEQLLREEPE 1099
+ +EEEL+ E++L E E +R+ E + K++ L Q EE +EE
Sbjct: 1610 HVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEE---KEEQY 1666
Query: 1100 KR-----------RRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148
K+ + QERER+ EE + E E R + Y E+EE
Sbjct: 1667 KKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEA-- 1724
Query: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208
+ Q ++ + + L+R E+E+L Q Q E++E E + + +E L +
Sbjct: 1725 -DSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQ---EKEETVSSHFEMRCQYQERLIKL 1780
Query: 1209 KRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQ 1268
+ + + EDQ Q E E++N + + + + E E + + Q++Q+L+
Sbjct: 1781 EHAEAKQHEDQSMIGHLQEELEEKNK-KYSLIVAQHVEKEGGK-------NNIQAKQNLE 1832
Query: 1269 HLLGEQQERDREQE------RRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR 1322
++ + Q+ +E+E ++ ++ D ++++ R E +E + K Q +Q+
Sbjct: 1833 NVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDG 1892
Query: 1323 EEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFR--EEELRHQEQGRKF--LE 1378
+ + + T+ K + L+Q + + Q D +F+ E Q+ G++ L+
Sbjct: 1893 RNKPTELLEENTEEK--SKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQ 1950
Query: 1379 EEQRLRRQE--RERKFLKEEQQLRCQEREQQLRQDRD-----------RKFREEEQQLSR 1425
++ R+ R+E +E + LK+E QERE++++Q+++ + RE QL++
Sbjct: 1951 KDLRMLRKEHQQELEILKKEYD---QEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQ 2007
Query: 1426 QERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQ---EREEQQLHRQE 1482
+E++ + +E + QE E + LE Q+ + +K E++ L+ +R E+ L +E
Sbjct: 2008 KEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDARE 2067
Query: 1483 RDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRR 1542
+ + Q + +E +K+ +Q+L +E +L Q Q+ L + +L+
Sbjct: 2068 EEMTAKVRDLQTQLEELQKKY-QQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKE 2126
Query: 1543 QERGQQRRQDRDRKFREEEQL 1563
QE +Q DR + E+ +
Sbjct: 2127 QEFREQIHNLEDRLKKYEKNV 2147
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 262 bits (669), Expect = 3e-69
Identities = 364/1568 (23%), Positives = 670/1568 (42%), Gaps = 171/1568 (10%)
Query: 463 ETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQ 522
+T + + R K+QL D+ R E L+LE E R+ ++ Q+ Q+ R RL
Sbjct: 210 QTPQFQMRRLKKQLA-DERSNRDE--LELELAENRKLLTEKDAQIAMMQQ--RIDRLALL 264
Query: 523 EEEERLQQRLRSEQQLRREQEE----RREQLLKREEEKRLEQERREQRLKREQEERRDQL 578
E++ E + R++ E R + LK+ ++ + E+ + ++++ + EE D
Sbjct: 265 NEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLS 324
Query: 579 LK-REEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPE----EERRQQL 633
K RE Q+L+ E E+ K + E LE++ + E+ L + EE+ + L
Sbjct: 325 FKLREFASHLQQLQDALNELTEEHSKATQ-EWLEKQAQLEKELSAALQDKKCLEEKNEIL 383
Query: 634 LKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQR---LKREHEEERREQELAEEEQ 690
Q E QL+ + + + L + E L+Q L + + + E+ E E+
Sbjct: 384 QGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETER 443
Query: 691 EQARERI---KSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRE---- 743
Q ++ + + + QL S QS + + + +E + + R +
Sbjct: 444 GQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASL 503
Query: 744 --------SELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERG-RQRLSARPPLREQR 794
+ +Q Q++E A +QQ +E++ Q +E++ +G R ++ +Q+
Sbjct: 504 TSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQK 563
Query: 795 ERQLR--AEE----RQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQ 848
E+QL+ AE+ RQ Q+ EE+E R+R K+L+ LE+E+ + QQ
Sbjct: 564 EQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQ 623
Query: 849 LQ---EEEDGLQED--QERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPA-LQEQLRKE 902
LQ E D Q Q +R E R + E ++ +H A+ A L+ QLR E
Sbjct: 624 LQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSE 683
Query: 903 QQLLQEEE----------EELQR------------EEREKRRRQEQERQYREEEQLQQEE 940
QQ E+E E+LQ EE ++R E Q R +L+ E
Sbjct: 684 QQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAET 743
Query: 941 EQLLREEREKRRRQERERQYRK--DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQ 998
L+ + + +R+ E ER RK + +LQQ E E RR E + + +
Sbjct: 744 RSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRR--ELAEAMAAQHTAES 801
Query: 999 EEEQLLREEREKRRRQEWERQYRKK-DELQQEEEQLLREEREKRRLQERERQYREEEELQ 1057
E EQL++E R R E +Q + + QE+ L+EE EK R +ELQ
Sbjct: 802 ECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKAR-----------QELQ 850
Query: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117
+ +E++ G E + ++ RQ + EL + L++ EK R ++ ++L
Sbjct: 851 EAKEKVAGIESHSEL--QISRQQNELAELHANLARALQQVQEKEVRAQKLA-----DDLS 903
Query: 1118 QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLRE-------EPEKRRRQE----- 1165
+E++ +E R + L R+ E++E E L++E +PE Q+
Sbjct: 904 TLQEKMAATSKEVARLETLVRKAGEQQETASRE--LVKEPARAGDRQPEWLEEQQGRQFC 961
Query: 1166 -----LERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQR--QKRKQRYRDED 1218
L+ RE E++ E E+L E + Q++E + ++E E+ R Q+R + D
Sbjct: 962 STQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLA 1021
Query: 1219 QRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERD 1278
+ + E +NA+ + +V + L + + +D Q+L L G + +
Sbjct: 1022 LEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKD----QELAKLRGLEAAQI 1077
Query: 1279 REQERRRWQQRDRHFPEEEQLEREE---------QKEAKRRDRKSQEEKQLLREEREEKR 1329
+E E R + +EQL ++E Q EA R + + + LR E +
Sbjct: 1078 KELEELRQTVKQL----KEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAE--VSK 1131
Query: 1330 RRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERE 1389
Q+ ++ + + L + E + R ERD + + +E+ ++ + L +RE
Sbjct: 1132 LEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRE 1191
Query: 1390 -RKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKF 1448
F + Q E E + + R R+ E + L + + +QV +E E K
Sbjct: 1192 LAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLI-SSLEEEVSILNRQVLEKEGESKE 1250
Query: 1449 LEEEQQLRQERHRKFREEEQLLQ-EREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE 1507
L+ E+ +K E +LLQ E ER EE Q LR + ++ +
Sbjct: 1251 LKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASEN 1310
Query: 1508 LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQER 1567
LR + + EE + Q KF Q+EQ L + Q + + L Q+
Sbjct: 1311 LRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQL 1370
Query: 1568 EEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQL 1627
+ +Q + ++R R+ LE+ K + LR E R RE +L
Sbjct: 1371 QAEQAAAEKRHRE-ELEQSK--------------------QAAGGLRAELLRAQRELGEL 1409
Query: 1628 LQEREEQQLHRQERDRKFLEEEP-----QLRRQEREQQLRHDRDRKFREEEQLLQEGEEQ 1682
+ R Q++ QER + L E QL ++ L + +R E L ++ E
Sbjct: 1410 IPLR--QKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEV 1467
Query: 1683 QLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRR 1742
+L Q R++ +E E +Q E Q +ELE + E + + +E+ R
Sbjct: 1468 ELD-QAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRF 1526
Query: 1743 QERYRKILEE-EQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEE 1801
QE +K+ + EQL + EQ + +E +K + +Q + ++Q+L++ ++ ++E
Sbjct: 1527 QEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKV-QQQKLKAVQAQGGESQQE 1585
Query: 1802 QLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREE 1861
R + + +L+ Q + E +LQ+E+ + ++ + +EQ + E+ ++E
Sbjct: 1586 AQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKEN 1645
Query: 1862 QELWQEEEQKRRQERERKLREEHIRRQQKEEQRH--RQVGEIKSQEGKGHGRLLEPGTHQ 1919
+EL E E+ + ++ L+ ++ ++ RH QV +++Q +L + G Q
Sbjct: 1646 KELRAEAERLGHELQQAGLK----TKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQ 1701
Query: 1920 FASVPVRS 1927
A+ ++S
Sbjct: 1702 VATDALKS 1709
Score = 249 bits (635), Expect = 2e-65
Identities = 360/1549 (23%), Positives = 672/1549 (43%), Gaps = 163/1549 (10%)
Query: 349 QQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 408
++L+++ +ER + + E R+ ++ Q+ QQ L E+Q + +
Sbjct: 217 RRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPK 276
Query: 409 REQQLRREQQ---LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETE 465
++LR + + +R + L++ Q + K E+ + ++++ + EE D + E
Sbjct: 277 ELEELRDKNESLTMRLHETLKQCQ-----DLKTEKSQMDRKINQLSEENGDLSFKLREFA 331
Query: 466 RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKR--QE 523
H QQL+ E L EE + QE E+Q + E+E + K+ +E
Sbjct: 332 SH-----LQQLQDALNE--------LTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEE 378
Query: 524 EEERLQQRL-RSEQQLRREQ----EERREQLLKREEEKRLEQERREQRLKREQEERRDQL 578
+ E LQ +L + E+ L + Q +E+ E L + + L+QE Q + R ++
Sbjct: 379 KNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEM 438
Query: 579 LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEE 638
L+ E +++ +L E+ E++ + + Q +EE E+ S+
Sbjct: 439 LETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQ-------ASQA 491
Query: 639 QEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIK 698
R Q+ E +++++ L LK++ +E++ + ++QEQA + ++
Sbjct: 492 HGARLTAQVASLTSELTTLNATIQQQDQEL-AGLKQQAKEKQAQLAQTLQQQEQASQGLR 550
Query: 699 SRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQ 758
++ QL S ++ ++ KQE R+ Q+ E E +E + A +Q
Sbjct: 551 HQVE----QLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQL 606
Query: 759 QEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKE 818
+ E+ + + ++ R SA+ + Q +R+ R+ E + E +E
Sbjct: 607 EALEKEKAAKLEILQQQLQVANEARDSAQTSV-TQAQREKAELSRKVEELQACVETARQE 665
Query: 819 QRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQL 878
Q Q + E ELQ E+++ +ER Q E+D LQE + + + + L
Sbjct: 666 QHEAQAQVAELELQLRSEQQKATEKERVAQ---EKDQLQEQLQALKESL----KVTKGSL 718
Query: 879 EEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYRE--EEQL 936
EEE++R A AL+EQ R +L E +++ +RE R+ E+ER R+ E +L
Sbjct: 719 EEEKRR------AADALEEQQRCISELKAETRSLVEQHKRE-RKELEEERAGRKGLEARL 771
Query: 937 QQ--EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEE 994
QQ E Q E + + Q+ + + +Q +++ Q+ E +Y
Sbjct: 772 QQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQY---G 828
Query: 995 ELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREERE-----------KRRL 1043
+ QE+ L+EE EK R++ E + + E Q+ R++ E +++
Sbjct: 829 AMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQV 888
Query: 1044 QERE-RQYREEEELQQEEEQLLGEERETRRRQEL-----ERQYRKEEELQQEEEQLLREE 1097
QE+E R + ++L +E++ +E R + L E+Q EL +E + +
Sbjct: 889 QEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQ 948
Query: 1098 PEKRRRQERERQCREEEELQ--QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155
PE Q+ + C + LQ + E + + E E+ R +E Q +++EE Q+E ++ R
Sbjct: 949 PEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVAR 1008
Query: 1156 EEPEKRRRQ---ELERQYREEEEL--------QQEEEQLLREEQEKRRQERERQYREEEE 1204
E+ R Q LE+ R E E+ Q+ E L+E E+E + +E +
Sbjct: 1009 LTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAK 1068
Query: 1205 LQRQKRKQRYRDEDQRSDLKWQWE----PEKENAVRDN-KVYCKGRENEQFRQLE--DSQ 1257
L+ + Q E+ R +K E EKE+A + GR +LE ++
Sbjct: 1069 LRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAE 1128
Query: 1258 LRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE-EEQLEREEQKEAKRRDRKSQE 1316
+ + Q Q + ER E ER +RD + QLE + Q+ + +
Sbjct: 1129 VSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASA 1188
Query: 1317 EKQLL----------REEREEK----RRRQETDRKFREEEQLLQEREEQPLRRQERDRKF 1362
+++L + E E K R RQE +RK L E E L RQ +++
Sbjct: 1189 QRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSL--EEEVSILNRQVLEKEG 1246
Query: 1363 REEELR-----HQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFR 1417
+EL+ E+ +K E + L+ + E+ +E Q LR++ +++ R
Sbjct: 1247 ESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQ-R 1305
Query: 1418 EEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQL---------RQERHRKFREEEQ 1468
+ L ++ + R EE + + KF ++EQ L Q + +
Sbjct: 1306 VASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKH 1365
Query: 1469 LLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ-ELRSQEPERKFLEEEQQLHRQ 1527
L Q+ + +Q ++R R+ LE+ +Q R R Q EL P R+ + E+++ +Q
Sbjct: 1366 LCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQ 1425
Query: 1528 QRQRKFLQEEQ---------QLRRQERGQQRRQDRDRKFREEEQLRQEREE--QQLSRQE 1576
R K EQ L + RG R + R+F E E L Q RE+ Q+L+
Sbjct: 1426 LRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVE-LDQAREKYVQELAAVR 1484
Query: 1577 RDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQ-Q 1635
D + RL E + Q R E E + EG + E ++F+E+ Q L + EQ +
Sbjct: 1485 ADAETRLAEVQREAQSTAR---ELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLE 1541
Query: 1636 LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFRE 1695
+ ++E+ ++ E +L D D+ + ++Q L+ + Q Q+ ++ +
Sbjct: 1542 VFQREQTKQVEELSKKLA----------DSDQASKVQQQKLKAVQAQGGESQQEAQRLQA 1591
Query: 1696 EEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQL 1755
+ +L+ Q +++ E +L+ ++ + + ++Q QE QEQLR E+ +K E ++L
Sbjct: 1592 QLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQEL-QEQLRSLEQLQK--ENKEL 1648
Query: 1756 RPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLR 1804
R E E Q+ K +E EQ + Q+RS E+ + ++QLR
Sbjct: 1649 RAEAERLGHELQQAGLKTKEAEQTCRHL-TAQVRSLEA-QVAHADQQLR 1695
Score = 239 bits (610), Expect = 2e-62
Identities = 346/1582 (21%), Positives = 674/1582 (42%), Gaps = 173/1582 (10%)
Query: 202 EEFPDEEQLRRRELLEL--RRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK 259
++ DE R LEL RK EK Q Q R+ + E + + KE E+
Sbjct: 221 KQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEE 280
Query: 260 LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ------RLR----REQQLRRK 309
L+++ L E +Q + L+ ++ + +R+ + ++ +LR QQL+
Sbjct: 281 LRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDA 340
Query: 310 QEEERREQQEERREQQERREQQEERREQQLRREQ--EERREQQLRREQEEERREQQLRRE 367
E E + +E E++ Q E+ L+ ++ EE+ E + + E QL+
Sbjct: 341 LNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDN 400
Query: 368 QEEERRE--------QQLRRE--------QQLRREQQLRREQQLRREQQLRREQQLRREQ 411
+E+ E + L++E QL+ ++ ++ ++E +L E+ E+
Sbjct: 401 PPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEE 460
Query: 412 QLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQER 471
+ + + Q + + E + + RL + L T + +Q++
Sbjct: 461 KQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQ-QQDQ 519
Query: 472 RKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQR 531
LK+ +E++ + L+++E+ Q R + + +++EQ+LK E++ R
Sbjct: 520 ELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQE-ATR 578
Query: 532 LRSEQQLRREQEERREQLLKREEE-KRLEQERREQRLKREQEERRDQLLKREEERRQQRL 590
QQL EER L +R+ K+LE +E+ K E +++ Q+ + Q +
Sbjct: 579 QDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSV 638
Query: 591 KREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRRE 650
+ Q E+ E K EE++ + R+EQ +++ Q + QLR E
Sbjct: 639 TQAQREKAELSRKVEELQACVETARQEQH---------------EAQAQVAELELQLRSE 683
Query: 651 QQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLES 710
QQ+ E+ + +E+++L+++L+ E + + EEE+ +A + ++ E
Sbjct: 684 QQKATEKE-RVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALE----------EQ 732
Query: 711 EADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES-ELQWQEEERAHRQQQEEEQRRDFTW 769
+ + K +R ++ +R R+E EE+R R+ E + Q+ AH Q + E RR+
Sbjct: 733 QRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAH-QAETEVLRRELAE 791
Query: 770 QWQAEEKSERGRQRLSARPPLREQRERQLRAEERQ---QREQRFLPEEEEKEQRRRQRRE 826
A+ +E ++L +R + EE Q +++ + +EE E+ R++ +E
Sbjct: 792 AMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQE 851
Query: 827 REKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRR 886
++++ +E +LQ + +L E L ++ + +E R QK L +++
Sbjct: 852 AKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRA-QKLADDLSTLQEKMA 910
Query: 887 HTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE 946
T L+ +RK + + EL +E RQ + + ++ Q + L
Sbjct: 911 ATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAM 970
Query: 947 EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLRE 1006
ERE + +G E E+ R E + +++EE Q+E ++ R
Sbjct: 971 EREAEQ---------------------MGNELERLRAALMESQGQQQEERGQQEREVARL 1009
Query: 1007 EREKRRRQ-EWERQYRKKDELQQEEEQLLREER-EKRRLQERERQYREEEELQQEEEQLL 1064
+E+ R Q + + + EL+ + L E+R E LQE E+E
Sbjct: 1010 TQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKE--------- 1060
Query: 1065 GEERETRRRQELERQYRKE-EELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQL 1123
G+++E + + LE KE EEL+Q +Q L+E+ K+ ++ + E + E
Sbjct: 1061 GKDQELAKLRGLEAAQIKELEELRQTVKQ-LKEQLAKKEKEHASGSGAQSEAAGRTEPTG 1119
Query: 1124 LREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQE-----LERQYREE-EELQ 1177
+ E + +LE+Q ++++E E+ L E R ++ L+ Q E+ +EL
Sbjct: 1120 PKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELG 1179
Query: 1178 QEEEQLLREEQEKR--RQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV 1235
+ L ++E R + + + E+E + Q + R E + S + E+E ++
Sbjct: 1180 HSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLIS---SLEEEVSI 1236
Query: 1236 RDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE 1295
+ +V K E+++ ++L ++ E ++ + +ER R Q +
Sbjct: 1237 LNRQVLEKEGESKELKRL----------------VMAESEKSQKLEERLRLLQAE----- 1275
Query: 1296 EEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRR 1355
A R +EE Q LREE E++R E L QE Q R
Sbjct: 1276 ----TASNSARAAERSSALREEVQSLREEAEKQR---------VASENLRQELTSQAERA 1322
Query: 1356 QE--RDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRD 1413
+E ++ K +E+ +EQ L+ E Q + L + + + EQ + R
Sbjct: 1323 EELGQELKAWQEKFFQKEQALSTLQLE-HTSTQALVSELLPAKHLCQQLQAEQAAAEKRH 1381
Query: 1414 RKFREEEQQLS---RQERDRKFRE------EEQQVRRQERERKFLEEEQQLRQERHRKFR 1464
R+ E+ +Q + R E R RE Q+V QER + L E+ E+ +
Sbjct: 1382 REELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLK 1441
Query: 1465 EEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524
+ LL E R R+FLE E Q R++ +E + E + E +++
Sbjct: 1442 KAHGLLAEENRGLGERANLGRQFLEVELD---QAREKYVQELAAVRADAETRLAEVQREA 1498
Query: 1525 HRQQRQRKFL---QEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKF 1581
R+ + + E +++ E Q+ +++R + + EQL + EQ +E +K
Sbjct: 1499 QSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKL 1558
Query: 1582 RLEEQKVRRQEQERKFM-----EDEQQLRRQEGQ-QQLRQERDRKFREDEQLLQEREEQQ 1635
+Q + Q+Q+ K + E +Q+ +R + Q +L+ + +K + E + E+ +
Sbjct: 1559 ADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAK 1618
Query: 1636 LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFRE 1695
H + ++ E + QLR E QL+ + E E+L E ++ L+ +E ++ R
Sbjct: 1619 THYDAKKQQNQELQEQLRSLE---QLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRH 1675
Query: 1696 EEQQLRRQERERKFLQEEQQLR 1717
Q+R E + +QQLR
Sbjct: 1676 LTAQVR--SLEAQVAHADQQLR 1695
Score = 233 bits (595), Expect = 1e-60
Identities = 316/1376 (22%), Positives = 600/1376 (43%), Gaps = 142/1376 (10%)
Query: 98 EKRARCDGKESL-LQDRR-QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQS 155
EK+A+ + + S LQD++ EE + + QLEE Q + QE+ L + +
Sbjct: 357 EKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQL- 415
Query: 156 EKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRREL 215
E L+Q Q + ER +E +L + +GH F +E+Q +
Sbjct: 416 ---ETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGH----FEEEKQQLSSLI 468
Query: 216 LELRR------KGREEKQQQRRERQDRVFQEEEE--KEWRKRETVLRKEEEKL------- 260
+L+ + +EE +Q + R+ + E +++++++L
Sbjct: 469 TDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQA 528
Query: 261 QEEEPQRQRELQEEEEQLRKLERQ--ELRRERQEEEQQQQRLRREQQLRRKQE------- 311
+E++ Q + LQ++E+ + L Q +L +++EQQ + + +Q+ R+
Sbjct: 529 KEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATA 588
Query: 312 -EERREQQEERREQQERREQQEERR-------EQQLRREQEERREQQLRREQEEERREQQ 363
EER ER ++ E E+ + +QQL+ E R Q Q + + +
Sbjct: 589 AEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAEL 648
Query: 364 LRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 423
R+ +E + + R+EQ + Q E QLR EQQ E +E+ + + QL+ +
Sbjct: 649 SRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATE----KERVAQEKDQLQEQL 704
Query: 424 QLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEET--ERHEQERRKQQLKRDQE 481
Q +E + E++RR EQ+ LK E + E+H++ER K +E
Sbjct: 705 QALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRER-----KELEE 759
Query: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE 541
E + L+ ++ E + + LRRE E + + E E+L + + + ++ +
Sbjct: 760 ERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYED 819
Query: 542 QEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQR 601
++ Q +E+ + + ++ ++E +E ++++ E Q + R+Q E E
Sbjct: 820 SQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQ-ISRQQNELAE-- 876
Query: 602 LKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRR---EQQERREQR 658
L L+Q + +E R ++ + Q+ + + +E R + L R EQQE +
Sbjct: 877 LHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRE 936
Query: 659 LKRE------EEEERLEQRLKREHEEERREQELAEEEQEQ---ARERIKSRIPKWQWQLE 709
L +E + E LE++ R+ + + E E EQ ER+++ + + Q Q +
Sbjct: 937 LVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQ-Q 995
Query: 710 SEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQ---EEERAHRQQQEEEQRRD 766
E +Q + +R ++ G+ + EK R E E++ Q E+R +E
Sbjct: 996 QEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHA 1055
Query: 767 FTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRE 826
T +E ++ +L + + +LR +Q +EQ E+E Q
Sbjct: 1056 LT----EKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEA 1111
Query: 827 REK------ELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRD---QKWRWQ 877
+ +L+ L E + ++ Q+ QE+ D L+ E R+ RD + + Q
Sbjct: 1112 AGRTEPTGPKLEALRAEVS-KLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQ 1170
Query: 878 LEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEE-ELQREEREKRRRQEQERQYREEEQL 936
LEE+ + H+ A + Q +L + +Q+ + E + + + R RQE ER+ L
Sbjct: 1171 LEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSL 1230
Query: 937 QQEEEQLLRE--EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEE 994
++E L R+ E+E ++ + + +K Q+ EE+L + E R E
Sbjct: 1231 EEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARA---AERS 1287
Query: 995 ELQQEEEQLLREEREKRR------RQEWERQYRKKDELQQE----EEQLLREER--EKRR 1042
+EE Q LREE EK+R RQE Q + +EL QE +E+ ++E+ +
Sbjct: 1288 SALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQ 1347
Query: 1043 LQERERQYREEEELQQEE--EQLLGEE--RETRRRQELERQYRK----EEELQQEEEQLL 1094
L+ Q E L + +QL E+ E R R+ELE+ + EL + + +L
Sbjct: 1348 LEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELG 1407
Query: 1095 REEPEKRRRQERER---QCREEEELQQEEEQLLR--------EEREKRRRQELERQYREE 1143
P +++ E+ER Q R E+ E+ +L+ E R R L RQ+ E
Sbjct: 1408 ELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEV 1467
Query: 1144 EEVQQEEEQL-----LREEPEKRR---RQELERQYREEEELQQEEEQL---LREEQEKRR 1192
E Q E+ + +R + E R ++E + RE E + + E + EE+++ +
Sbjct: 1468 ELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQ 1527
Query: 1193 QERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQ 1252
+ER++ + E+L+ +R+Q + E+ L + K + V +G E++Q Q
Sbjct: 1528 EERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQ 1587
Query: 1253 LEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDR 1312
+QL + Q+Q Q+E+ E + + ++ H+ ++Q +E Q++ + ++
Sbjct: 1588 RLQAQLNELQAQL-------SQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQ 1640
Query: 1313 KSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELR 1368
+E K+L E Q+ K +E EQ + Q +R E +++LR
Sbjct: 1641 LQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQ-VRSLEAQVAHADQQLR 1695
Score = 192 bits (488), Expect = 3e-48
Identities = 272/1162 (23%), Positives = 491/1162 (42%), Gaps = 170/1162 (14%)
Query: 58 LELLDLDSNGRVDFNEFLLFIFKVAQ-ACYYALGQATGLDEEKRARCDGKESLLQDRRQE 116
LE L+ + +++ + L + A+ + ++ QA E + + ++ ++ RQE
Sbjct: 606 LEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQE 665
Query: 117 EDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQ 176
+ + + + + +L+ Q QK E+ER E ++ E+ + L++ + +
Sbjct: 666 QHEAQAQVAELELQLRSEQ---QKATEKERVAQEKDQLQEQLQALKESLKVTKGS----- 717
Query: 177 RQEWQEREERRAEE--EQLQSCKGH---ETEEFPDEEQLRRRELLELR--RKGREEKQQQ 229
E E+RRA + E+ Q C ET ++ + R+EL E R RKG E + QQ
Sbjct: 718 ----LEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQ 773
Query: 230 ------------RRERQDRVFQE-----------EEEKEWRKRETVLRKEEEK------- 259
RRE + + + +E WR+R ++EE +
Sbjct: 774 LGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQE 833
Query: 260 ----LQEEEPQRQRELQEEEEQLRKLE-RQELRRERQEEEQQQQRLRREQQLRRKQEEER 314
L+EE + ++ELQE +E++ +E EL+ RQ+ E + + L++ QE+E
Sbjct: 834 QLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEV 893
Query: 315 REQQ-----EERREQQERREQQEERREQQLRR--EQEERREQQLRRE-------QEEERR 360
R Q+ +E+ ++ R E +R+ EQ+E ++L +E Q E
Sbjct: 894 RAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLE 953
Query: 361 EQQLRR-----------EQEEERREQQLRR----------EQQLRREQQLRREQQLRREQ 399
EQQ R+ E+E E+ +L R +QQ R QQ R +L +E+
Sbjct: 954 EQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQER 1013
Query: 400 QLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQK------HEQERREQRLKREQEE 453
R + L E+ R E ++R + L ++ E Q+ E+E ++Q L + +
Sbjct: 1014 G-RAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGL 1072
Query: 454 RRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEE 513
+K EE R ++ K+QL + ++E + E R E + + LR E +
Sbjct: 1073 EAAQIKELEEL-RQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSK 1131
Query: 514 RREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEE 573
+Q K+QE+ + L++ L +E+ R E++ E L + EEK E + L Q E
Sbjct: 1132 LEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRE 1191
Query: 574 RRDQLLKREEERRQQRLKREQEERLEQRLKREEVER-------LEQEER--REQRLKREE 624
L + Q K E E + + R+E ER LE+E Q L++E
Sbjct: 1192 -----LAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEG 1246
Query: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLE---QRLKREHEEERR 681
+E ++ ++ E+ ++ +++LR Q E + E L Q L+ E E++R
Sbjct: 1247 ESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRV 1306
Query: 682 EQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRR 741
E +E ER + +L E A Q K + +K++ Q + +
Sbjct: 1307 ASENLRQELTSQAERAE--------ELGQELKAWQEKFF---QKEQALSTLQLEHTSTQA 1355
Query: 742 RESEL--------QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLR-- 791
SEL Q Q E+ A ++ EE + + R ++ L PLR
Sbjct: 1356 LVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQK 1415
Query: 792 ----EQRERQLRAEERQQREQRFLPEEEE---KEQRRRQRREREKELQFLEEEEQLQRRE 844
E+ +QLRAE+ EQ + ++ E+ R QFLE E R +
Sbjct: 1416 VAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREK 1475
Query: 845 RAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQ 904
Q+L ++ D E R ++ QR Q +LE + + +
Sbjct: 1476 YVQELA----AVRADAETRLAEVQREAQSTARELE--------------VMTAKYEGAKV 1517
Query: 905 LLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEE---QLLREEREKRRRQERERQYR 961
+ EE + Q EER+K Q ++ + + EQ +Q EE +L ++ + +Q++ + +
Sbjct: 1518 KVLEERQRFQ-EERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQ 1576
Query: 962 KDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYR 1021
Q+E Q L + + + Q +K+ E Q E+ + +K++ QE + Q R
Sbjct: 1577 AQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLR 1636
Query: 1022 KKDELQQEEEQLLRE-EREKRRLQERERQYREEEELQQEEEQLLGEERETRRR-QELERQ 1079
++LQ+E ++L E ER LQ+ + +E E Q L + R + ++Q
Sbjct: 1637 SLEQLQKENKELRAEAERLGHELQQAGLKTKEAE---QTCRHLTAQVRSLEAQVAHADQQ 1693
Query: 1080 YRKEEELQQEEEQLLREEPEKR 1101
R + Q + L EP+ +
Sbjct: 1694 LRDLGKFQVATDALKSREPQAK 1715
Score = 115 bits (287), Expect = 5e-25
Identities = 177/709 (24%), Positives = 304/709 (42%), Gaps = 114/709 (16%)
Query: 38 EREFGAVLRRPHDPKTVDLILELL---DLDSNGRVDFNEFLLFIFKVAQACYYALGQATG 94
ERE A L + DL LE +L+ + NE + + +A +AL + G
Sbjct: 1003 EREV-ARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEG 1061
Query: 95 LDEEKRARCDGKESL----LQDRRQEEDQRRFEPRDRQLEEEPGQRRRQ----------- 139
D+E A+ G E+ L++ RQ Q + + ++ E G +
Sbjct: 1062 KDQEL-AKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGP 1120
Query: 140 KRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGH 199
K + E+++ E+Q +KQ+ EQ D R E R R ER + E LQ
Sbjct: 1121 KLEALRAEVSKLEQQCQKQQ--EQADSLERSLEAERA-----SRAERDSALETLQGQLEE 1173
Query: 200 ETEEFPDEEQL---RRRELLELRRKGREEKQ------------QQRRERQDRVFQEEEEK 244
+ +E + +REL R K ++ + +Q ER++ + EE+
Sbjct: 1174 KAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEE 1233
Query: 245 EWRKRETVLRKEEE--KLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR 302
VL KE E +L+ + Q+ EE+LR L+ + + E+ LR
Sbjct: 1234 VSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSA-LRE 1292
Query: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEE--RREQQLRREQEEERR 360
E Q R++ E++R E R++ + ++ E Q+L+ QE+ ++EQ L Q E
Sbjct: 1293 EVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTS 1352
Query: 361 EQ--------------QLRREQE--EERREQQLRREQQLR---REQQLRREQQLRREQQL 401
Q QL+ EQ E+R ++L + +Q R + LR +++L L
Sbjct: 1353 TQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPL 1412
Query: 402 RRE--QQLRREQQLRREQQLRREQ--QLRREQEEERHEQKHEQERRE---QRLKREQEER 454
R++ +Q R QQLR E+ EQ L++ E + ER Q L+ E ++
Sbjct: 1413 RQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQA 1472
Query: 455 RDWLKREEETERHEQERRKQQLKRDQEEERRE----------RWLKLEEEERREQQERRE 504
R+ +E R + E R +++R+ + RE +K+ EE +R Q+ER++
Sbjct: 1473 REKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQK 1532
Query: 505 QQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERRE 564
+ EQ E ++ +Q EE L ++L Q + Q+++ LK + + E ++
Sbjct: 1533 LTAQVEQLEVFQREQTKQVEE--LSKKLADSDQASKVQQQK----LKAVQAQGGESQQEA 1586
Query: 565 QRLKREQEERRDQLLKREE------------------ERRQQRLKREQEERLEQRLKREE 606
QRL+ + E + QL ++E+ +++Q + +EQ LEQ K +
Sbjct: 1587 QRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENK 1646
Query: 607 VERLEQE----ERREQRLKREEPEEERRQ---QLLKSEEQEERRQQQLR 648
R E E E ++ LK +E E+ R Q+ E Q QQLR
Sbjct: 1647 ELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLR 1695
Score = 70.1 bits (170), Expect = 2e-11
Identities = 83/364 (22%), Positives = 160/364 (43%), Gaps = 31/364 (8%)
Query: 128 QLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERR 187
Q E+ ++R ++ EQ ++ A G R E QR EL RQ+ E+E
Sbjct: 1371 QAEQAAAEKRHREELEQSKQAAGGL-------RAELLRAQRELGELIPLRQKVAEQERTA 1423
Query: 188 AEEEQLQSCKGHETEEFPDEEQLRRRE-LLELRRKGREEKQQQRRERQDRVFQEEEEKEW 246
+QL++ K E+ L++ LL +G E+ R+ + + EK
Sbjct: 1424 ---QQLRAEKASYAEQL---SMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYV 1477
Query: 247 RKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLE---------RQELRRERQEEEQQQ 297
++ V E +L E + + Q +E E K E RQ + ERQ+ Q
Sbjct: 1478 QELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQV 1537
Query: 298 QRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE 357
++L Q+ + KQ EE ++ + Q + QQ++ + Q + + ++ Q+L + Q
Sbjct: 1538 EQLEVFQREQTKQVEELSKKLAD--SDQASKVQQQKLKAVQAQGGESQQEAQRL-QAQLN 1594
Query: 358 ERREQQLRREQEEERREQQLRREQ---QLRREQQLRREQQLRREQQLRREQQLRREQQLR 414
E + Q ++EQ E + Q+ + + +++Q ++QLR +QL++E + R + R
Sbjct: 1595 ELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAER 1654
Query: 415 REQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETE--RHEQERR 472
+L++ +E E+ + E ++ ++ RD K + T+ + + +
Sbjct: 1655 LGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQA 1714
Query: 473 KQQL 476
K QL
Sbjct: 1715 KPQL 1718
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 258 bits (660), Expect = 3e-68
Identities = 247/1082 (22%), Positives = 533/1082 (49%), Gaps = 132/1082 (12%)
Query: 207 EEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVL------------- 253
+E +R +E++ REE+Q Q++ R D + EE + +K + V+
Sbjct: 1334 QEVIRHKEVMP-----REEEQAQKKAR-DMLGLEETQVILKKGKKVIFLEPGNVTMGKEI 1387
Query: 254 -RKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE 312
+KEE+K ++ P++ R+ ++E ++ K++R+ + ER E+ ++ E+++ +++ +
Sbjct: 1388 SKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGK 1447
Query: 313 ----ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368
ER ++ ++ + +Q + + +EE ++ L+ E++ + ++L E+
Sbjct: 1448 LVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEE 1507
Query: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428
E + +++L+ E+ + + + + +EQQ + E+++ E+++ RE
Sbjct: 1508 EMLQEDKKLKWEEWKQVWENMLSSKS--------------KEQQYKDEEEVTLEEEVSRE 1553
Query: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488
EE+ + EQ R +E W + + R E++R +++ K QEEE
Sbjct: 1554 GEEKEQQVTEEQ--------RHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEE----- 1600
Query: 489 LKLEEEERREQQERREQ-----QLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQE 543
KL +EER+ QE R+ ++ ++ E + K ++EE L QR Q +
Sbjct: 1601 -KLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLA 1659
Query: 544 ERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK 603
++R++L K+ E+ E+E+ ++ + E + K EE ++++ QE+ L Q L+
Sbjct: 1660 QKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELE 1719
Query: 604 REEVERLEQEERREQRLKREEPE-EERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662
E + +E+ +E+ L +EE + E +++L + EE ++++L E+ + ++
Sbjct: 1720 ELEWD-MEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLI 1778
Query: 663 EEEERLEQRLKREHEEE----RREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSK 718
+E+E+L Q ++ EEE R+ ++L E++ + A++R +W +E E +
Sbjct: 1779 QEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKR-----ERWINSME-ELTKNKMI 1832
Query: 719 VYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTW----QWQAE 774
+Y + + ++ +++EK +R+ L + +E H ++Q + + Q E
Sbjct: 1833 LYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVE 1892
Query: 775 EKSERGRQR-LSARPPLREQRERQLRAEERQQREQRFLPEEEEK---EQRRRQRREREK- 829
EK + ++ + + L E ++ ++ E+ ++Q L +E+ K E+ Q ++R +
Sbjct: 1893 EKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRG 1952
Query: 830 ELQFLEEEEQLQRRERAQQLQEEEDGLQEDQE---RRRSQEQRRDQKWRWQLEEERKRRR 886
EL +EE+ L + +L EE+ L E +E + + E R +K Q+E+E R+
Sbjct: 1953 ELDIAKEEKALNLEMK--RLAEEKMRLVEGKETLSKGETPETSRQRKMT-QVEQELFERK 2009
Query: 887 HTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQE-----QERQYREEEQLQQEEE 941
+L K L E ++L EE E+ + + E R Q Q + + +L ++ E
Sbjct: 2010 LSLEEKILLHED-----RILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRE 2064
Query: 942 QLLREEREKRR-RQERERQYRKDKKLQQKEEQLLGEE-----PEKRRRQEREKKYREEEE 995
L +E + + + ++ R ++KL Q+E ++ + E+R E+ K +E +
Sbjct: 2065 SLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWD 2124
Query: 996 LQQEEEQLLREEREKRRRQ-----EWERQYRKKDELQQEEEQLLREERE----------- 1039
++ +L ++E++ R+Q + R K++++ +EE +L R+ E
Sbjct: 2125 FSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGI 2184
Query: 1040 ---------KRRLQERERQYREE---EELQQEEEQLLGEERETRRRQELERQYRKEEELQ 1087
KRR ++R+ R + E+ + +++ EE + + L + K+E L
Sbjct: 2185 EEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLS 2244
Query: 1088 QEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELER--QYREEEE 1145
EEE+ EE E+ + RE + +EE + EE+Q+ +EE EK+++++ ++ + +E+EE
Sbjct: 2245 SEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEE 2304
Query: 1146 VQQEEEQLLREEPEKRR--RQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEE 1203
V +E+E+++ EE + +E E EEE+ +E+E L +E+Q K +++R + R E
Sbjct: 2305 VFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRE 2364
Query: 1204 EL 1205
+
Sbjct: 2365 RV 2366
Score = 248 bits (634), Expect = 3e-65
Identities = 248/1005 (24%), Positives = 499/1005 (49%), Gaps = 130/1005 (12%)
Query: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE 156
EEK + +GK +++ +D ++ +Q+ E + + ++E E+ L + EE
Sbjct: 1438 EEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEE--- 1494
Query: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELL 216
+L Q + EE Q + + EE + E + S K E +++ DEE++ E
Sbjct: 1495 ---KLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKE-QQYKDEEEVTLEE-- 1548
Query: 217 ELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEE 276
E+ R+G EEK+QQ E Q + +EE +W + + ++ + +++ Q +R+L +EEE
Sbjct: 1549 EVSREG-EEKEQQVTEEQRHI---QEEHKWAR----IHRKRARAEKKRAQEERKLAQEEE 1600
Query: 277 QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE 336
+L + ERQ + ER+ + + + ++++ Q E + Q+EE Q+ + QE +
Sbjct: 1601 KLAQEERQLAQEERKLAQAYVKITQDDREMA--QAEGKFAQKEETLAQRGEKLSQEAEKL 1658
Query: 337 QQLRREQEERREQQLRREQEEERREQQLRREQE--EERREQQLRREQQLR-REQQLRREQ 393
Q R++ ++ E+ R E++ ++ +L + ++ E+ +REQ L +E++L +E
Sbjct: 1659 AQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQEL 1718
Query: 394 QLRREQQLRREQQLRREQQLRREQ-QLRREQQLRREQEEERHEQKHEQERREQRLKREQE 452
+ E + E+ +E++L +E+ +L E++ E+EE Q+ + E +L +E+E
Sbjct: 1719 E---ELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEE 1775
Query: 453 ---ERRDWLKREEETERHEQER---RKQQL--KRDQEEERRERWLKLEEEERREQ----Q 500
+ ++ L + +E E+ER +++QL K+ + ++RERW+ EE + + Q
Sbjct: 1776 LLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQ 1835
Query: 501 ERREQQLRREQEERREQRLKRQEEEERLQQRL-RSEQQLRREQEE---------RREQLL 550
++ Q ++ + +E+ +R+E ++RL S++QL + + + + E+ L
Sbjct: 1836 KKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKL 1895
Query: 551 KREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR--EEVE 608
+E+E ++++ + +++ + D L K++E+ Q+++K E+ + Q KR E++
Sbjct: 1896 TQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELD 1955
Query: 609 RLEQEERREQRLKREEPEEER----RQQLLKSEEQEERRQQQLRREQQERREQRLKREEE 664
++E+ +KR E+ R ++ L K E E RQ+++ + +QE E++L EE+
Sbjct: 1956 IAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEK 2015
Query: 665 ----EERL----EQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQ 716
E+R+ E + + E R Q + + Q + + + I K + S+ A+
Sbjct: 2016 ILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESL--SKEPAKL 2073
Query: 717 SKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEK 776
+K+ +K R+ QEE + + + +E R +Q + + + +W EK
Sbjct: 2074 NKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIK-----EWDFSEK 2128
Query: 777 SERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEE 836
R + E++ R+QR L + RR KE + EE
Sbjct: 2129 -----------------RSELTKDEKKLARKQRKLAN--------KMRRMINKEEKMTEE 2163
Query: 837 EEQLQRRERAQQLQEEEDGLQEDQE---------RRRSQEQRRD---QKWRWQLEEERKR 884
E +L R+ L +EE+G E++E R+R + +R D +K+ Q++E
Sbjct: 2164 ESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESE 2223
Query: 885 RRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLL 944
H +L ++L K++ L EEEEE REE E+R E+E EEE+ ++EEE
Sbjct: 2224 E-HFSEEMESLLDELEKQESLSSEEEEE--REEEEER---EEEEVREEEEERKEEEE--- 2274
Query: 945 REEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEE-QL 1003
+ ++ E+E + +K KK ++K+E++ QE+E+ + E+EE+ EEE +
Sbjct: 2275 ----GEEKQVEKEEEEKKKKKKEKKKEEV----------QEKEEVFEEKEEIMSEEETES 2320
Query: 1004 LREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERER 1048
L +E E+ E + ++ E+ ++E+Q +E+ ++ L+ RER
Sbjct: 2321 LSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRER 2365
Score = 246 bits (628), Expect = 2e-64
Identities = 326/1472 (22%), Positives = 656/1472 (44%), Gaps = 174/1472 (11%)
Query: 546 REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK-- 603
R LL+ +++ +E ++Q + EE D LL Q L + E+RL + L
Sbjct: 986 RTSLLQLTQKQETFREMQQQMIG---EEPLDHLLGMRATDLQI-LSTQVEQRLNENLTLS 1041
Query: 604 -REEVERLEQEERREQRLKR--EEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLK 660
R+E + LK + P ++ + +RR Q ++ ++ + LK
Sbjct: 1042 HRDEKPAFSLDVSMPSELKSSLKPPTVSEESEVAIKPSKGQRRGQAGVKKHSQKWLRGLK 1101
Query: 661 REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVY 720
+ +E + + + E+ E A E E+A + +L + D+ Q K
Sbjct: 1102 KTKERDSKQMSTEPGLLEDESGTEAAPIEMEEASVYSQWSSSTSVIKLSKDVDS-QEKDI 1160
Query: 721 SRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERG 780
S+ +R Q+ +KR ++ + Q+ ++ H+++ +E + + E+
Sbjct: 1161 SKDHIALTLKRLQKIRDKRDKKATA---QKLKKKHKKKGKEAKVINEETTPPVMEQPVTK 1217
Query: 781 RQRLSARPPLREQRERQLRAEERQQREQ--RFLPEEEEKEQRRRQRREREKELQFLEEEE 838
+ ++ R R + R+ R + Q + + + F +E
Sbjct: 1218 KVKIQGRGASGISGRRSTAGDGSSWRDDLCRLMALRISGSQTKMSENLNAELVTFAQE-- 1275
Query: 839 QLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQ 898
L R + +L +E L ++ S+ D W E+ KP ++
Sbjct: 1276 MLVDRHPSWELFQEICPLL----KKESKVLLEDLDWDVVPPEK----------KPIFIQE 1321
Query: 899 LRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKR------- 951
+ ++Q +E+ R +E R+E++ Q + + L EE Q++ ++ +K
Sbjct: 1322 GAIREDMIQGVTQEVIRH-KEVMPREEEQAQKKARDMLGLEETQVILKKGKKVIFLEPGN 1380
Query: 952 -------RRQERERQYRKDKKLQQK---EEQLLGEEPEKRRRQEREKKYREEEELQQEEE 1001
++E ++ ++K K +K +E+ +G+ + ++ER+ E EE+ EE
Sbjct: 1381 VTMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMS-EEVEEMATLEE 1439
Query: 1002 QLLREEREK---RRRQEWERQYRKKDELQQ------EEEQLLREEREKRRLQERERQYRE 1052
+++++E + R W+ + DE +Q + + +EE EKR LQE E+ ++
Sbjct: 1440 KVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQA 1499
Query: 1053 EEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE 1112
E+L EEE L +++ K EE +Q E +L + +E+Q ++
Sbjct: 1500 GEKLSPEEEMLQEDKK------------LKWEEWKQVWENMLSSK-------SKEQQYKD 1540
Query: 1113 EEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE 1172
EEE+ EEE + E E++ +Q E Q +EE + R EK+R QE + +E
Sbjct: 1541 EEEVTLEEE--VSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQE 1598
Query: 1173 EEELQQEEEQLLREEQ------------EKRRQERERQYREEEELQRQKRKQRYRDEDQ- 1219
EE+L QEE QL +EE+ ++ + E ++ ++EE Q+ ++ ++ ++
Sbjct: 1599 EEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKL 1658
Query: 1220 ---RSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQL---EDSQLRDRQSQQDLQH--LL 1271
R L +WE + A + K+ KG + + + + + +L R+ D Q L
Sbjct: 1659 AQKRKKLAKKWE---KVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELA 1715
Query: 1272 GEQQERDREQERRRW------QQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREER 1325
E +E + + E W Q+ + E+++L EE+ A +R++ S+EE +L +EE
Sbjct: 1716 QELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEE 1775
Query: 1326 ---EEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQ---------G 1373
+EK + + K EEE+ L + EQ + ++ + + RE + E+
Sbjct: 1776 LLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQ 1835
Query: 1374 RKFLEEEQRLRRQERERKFLKEEQQLRCQER----EQQLRQDRDR-----KFREEEQQLS 1424
+K L +E++ QE+E+ ++E L +ER ++QL Q +++ K + ++
Sbjct: 1836 KKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKL 1895
Query: 1425 RQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERD 1484
QE++ +++E+ E E+K ++ E L +++ + +E+ +L E+ Q ++ R
Sbjct: 1896 TQEKETVIKKKEKLA---ETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRG 1952
Query: 1485 RKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQE 1544
+ +E++ E R E+++R E + + E RQRK Q EQ+L ++
Sbjct: 1953 ELDIAKEEKALNLEMKR-LAEEKMRLVEGKETLSKGETP--ETSRQRKMTQVEQELFERK 2009
Query: 1545 RGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRR-QEQERKFMEDEQQ 1603
+ + E+ L E E + E R R+ Q R+ + RK ++ +
Sbjct: 2010 LSLEEKI----LLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRES 2065
Query: 1604 LRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRH 1663
L ++ + + +K DE+ L + EE ++ + +R F++E RR EQ
Sbjct: 2066 LSKEPAKLNKILKALQKLTRDERKLTQ-EEIKMTKMKR-ALFVKE----RRLSIEQSKLD 2119
Query: 1664 DRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQ-ERERKFLQEEQQLRRQELE 1722
++ F E+ L + E++ R+Q R+ ++RR +E K +EE +L R+ E
Sbjct: 2120 IKEWDFSEKRSELTKDEKKLARKQ------RKLANKMRRMINKEEKMTEEESKLARKHSE 2173
Query: 1723 RKFREEEQ--LRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE---- 1776
+EE+ + +E L+R+ R RK + E+ Q+ E + F EE
Sbjct: 2174 VILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESL 2233
Query: 1777 -----------EQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEE 1825
+ +EREE++ R +E R+ EE + +E EE+Q+ ++ + K + +E
Sbjct: 2234 LDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKE 2293
Query: 1826 EQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHI 1885
++ + ++++ + +E++ + +EE+ + EE+ EEE R +E +K ++ +
Sbjct: 2294 KKKEEVQEKEEVFEEKE-EIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKL 2352
Query: 1886 RRQQKEEQRHRQ-VGEIKSQEGKGHGRLLEPG 1916
+ Q+++ R R+ V I G GR + G
Sbjct: 2353 QEQRRKSLRGRERVLSILRGVPHGKGRAIRLG 2384
Score = 244 bits (622), Expect = 8e-64
Identities = 253/1041 (24%), Positives = 513/1041 (49%), Gaps = 91/1041 (8%)
Query: 105 GKESLLQDRRQEEDQRRFEPRDRQ------LEEEPGQRRRQKRQEQERELAEGEEQSEKQ 158
G ++ ++ ++E+++ F+ +Q E + G+ +R+ +E+ E EE + +
Sbjct: 1379 GNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLE 1438
Query: 159 ERLEQRDRQRRDEELWRQRQEWQER--EERRAEEEQLQSCKGHETEEFPDEEQLRRRELL 216
E++ +++ + E Q+W++ E ++ E +S K + E E++L + E
Sbjct: 1439 EKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEW---EKRLLQEEE- 1494
Query: 217 ELRRKGREEKQQQRRERQDRVFQEEEEKE-WRKRETVLRKEEEKLQEEEPQRQRELQEEE 275
+L + G + ++ ++D+ + EE K+ W + KE++ EEE + E+ E
Sbjct: 1495 KLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREG 1554
Query: 276 EQLRKLERQELRRERQEEEQQQ-QRLRREQQLRRKQEEERREQQEERREQQERREQQEER 334
E+ + +E R ++E + + R R + +R QEE + Q+EE+ Q+ER+ QEER
Sbjct: 1555 EEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEER 1614
Query: 335 REQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQ 394
+ Q + + + + E + ++E+ L Q E+ Q+ + Q R++ + E+
Sbjct: 1615 KLAQAYVKITQDDREMAQAEGKFAQKEETLA--QRGEKLSQEAEKLAQKRKKLAKKWEKV 1672
Query: 395 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEER 454
R E++L ++ E + Q++ E+ +REQ + E++ QE E L+ + EE
Sbjct: 1673 AREEEKLAKKGGKLAEVKNILAQKV--EELPQREQNLDWQEKELAQELEE--LEWDMEE- 1727
Query: 455 RDWLKREEETERHEQERRKQQLKRDQEEERRERWL--KLEEEERREQQERREQQLRREQE 512
L +EE E+ + ++ K+ EEE W KL EEE + QE E+ L +E+E
Sbjct: 1728 ---LSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQE--EELLIQEKE 1782
Query: 513 ERREQRLKRQEEEERLQQRLRS--EQQLRREQEERR-----EQLLKRE----EEKRLEQE 561
+ + + K EEEERL ++ E++++ Q+ R E+L K + ++K L QE
Sbjct: 1783 KLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQE 1842
Query: 562 RREQRLKREQEERRDQLLKREEER----RQQRLKREQEERLEQRLKREEVERLEQEERRE 617
++ ++E+ +R + L +ER ++Q ++ + + + ++ + E+L QE +E
Sbjct: 1843 KKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQE--KE 1900
Query: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHE 677
+K++E E ++L++ E+ ++Q++L +E+ +L E+ + ++RL+ E +
Sbjct: 1901 TVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKM-----KLALEKAMVQGKKRLRGELD 1955
Query: 678 EERREQELAEEEQEQARERIKSRIPKWQWQL---ESEADARQSKVYSRPRKQEGQRRRQE 734
+ E+ L E + A E K R+ + + L E+ +RQ K+ +QE R+
Sbjct: 1956 IAKEEKALNLEMKRLAEE--KMRLVEGKETLSKGETPETSRQRKMTQV--EQELFERKLS 2011
Query: 735 QEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQ-----AEEKSERGRQRLSARPP 789
EEK E + EE + + E + + Q Q A K + R+ LS P
Sbjct: 2012 LEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPA 2071
Query: 790 LREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQL 849
+ + L+A ++ R++R L +EE K + +R KE + E+ +L +E
Sbjct: 2072 ---KLNKILKALQKLTRDERKLTQEEIK-MTKMKRALFVKERRLSIEQSKLDIKE--WDF 2125
Query: 850 QEEEDGLQEDQERRRSQEQRRDQKWRWQL-EEERKRRRHTLYAKPALQEQLRKEQQLLQE 908
E+ L +D+++ ++++ K R + +EE+ + A+ + L E++ E
Sbjct: 2126 SEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIE 2185
Query: 909 EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
EEE + +R R+R+E +R + +E+ + +++ EE + + K + L
Sbjct: 2186 EEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSS 2245
Query: 969 KEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ 1028
+EE+ EE E+ + RE++ +EE + EE+Q+ +EE EK+++ ++ +KK+E+Q+
Sbjct: 2246 EEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKK----KKEKKKEEVQE 2301
Query: 1029 EEEQLLREEREKRRLQERERQYREEEELQQEEE-QLLGEERETRRRQELERQYRKEEELQ 1087
+EE + E+EE+ EEE + L +E E LE + +E+E+
Sbjct: 2302 KEE-----------------VFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEIL 2344
Query: 1088 QEEEQLLREEPEKRRRQERER 1108
++E+Q +E ++ + RER
Sbjct: 2345 KKEKQFKLQEQRRKSLRGRER 2365
Score = 239 bits (611), Expect = 1e-62
Identities = 330/1477 (22%), Positives = 667/1477 (45%), Gaps = 195/1477 (13%)
Query: 172 ELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPD-EEQLRRRELLELRRKGREEKQQQR 230
+L ++++ ++E +++ EE L G + Q+ +R L R+EK
Sbjct: 991 QLTQKQETFREMQQQMIGEEPLDHLLGMRATDLQILSTQVEQRLNENLTLSHRDEKPAFS 1050
Query: 231 RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRER 290
+ V E K K TV + E ++ + QR+ + ++ + L + +ER
Sbjct: 1051 LD----VSMPSELKSSLKPPTVSEESEVAIKPSKGQRRGQAGVKKHSQKWLRGLKKTKER 1106
Query: 291 QEEEQQQQRLRREQQLRRK-----QEEERREQQEERREQQERREQQEERREQQLRREQEE 345
++ + E + + EE Q + + + +E+ + ++
Sbjct: 1107 DSKQMSTEPGLLEDESGTEAAPIEMEEASVYSQWSSSTSVIKLSKDVDSQEKDISKDHIA 1166
Query: 346 ---RREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR--REQQLRREQQLRRE-- 398
+R Q++R +++++ Q+L+++ +++ +E ++ E+ EQ + ++ +++
Sbjct: 1167 LTLKRLQKIRDKRDKKATAQKLKKKHKKKGKEAKVINEETTPPVMEQPVTKKVKIQGRGA 1226
Query: 399 -----------------QQLRREQQLRRE-QQLRREQQLRREQ-QLRREQEEERHEQKHE 439
L R LR Q + + L E +E +RH
Sbjct: 1227 SGISGRRSTAGDGSSWRDDLCRLMALRISGSQTKMSENLNAELVTFAQEMLVDRHPSWEL 1286
Query: 440 QERREQRLKREQE---ERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEER 496
+ LK+E + E DW + E++ ++ E + + E
Sbjct: 1287 FQEICPLLKKESKVLLEDLDW-------DVVPPEKKPIFIQEGAIREDMIQGVTQEVIRH 1339
Query: 497 REQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEK 556
+E R E EQ +++ + + EE + + ++ + L +++ K+EE+K
Sbjct: 1340 KEVMPREE-----EQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEEKK 1394
Query: 557 RLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEER--LEQRLKREEVERLEQEE 614
++ ++ R K Q+ER+ +KRE + ++ + E EE LE+++ ++E +L E
Sbjct: 1395 TFQKSPKQGR-KAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQE-GKLVMIE 1452
Query: 615 RREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKR 674
R ++ +E +Q E R+ + +E+ E+R L+ EE+ + ++L
Sbjct: 1453 RTPSWQDWKKAWDEWKQV-----HGETRKSWKAWKEEWEKR--LLQEEEKLHQAGEKLSP 1505
Query: 675 EHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQE 734
E E + +++L EE +Q W+ L S++ +Q K +
Sbjct: 1506 EEEMLQEDKKLKWEEWKQV----------WENMLSSKSKEQQYK---------------D 1540
Query: 735 QEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQR 794
+EE E + +E+E QQ EEQR Q E K R ++ + R Q
Sbjct: 1541 EEEVTLEEEVSREGEEKE----QQVTEEQRHI-----QEEHKWARIHRKRARAEKKRAQE 1591
Query: 795 ERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEED 854
ER+L EE + ++ +EE++ + + + + + + E + ++E + L + +
Sbjct: 1592 ERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKE--ETLAQRGE 1649
Query: 855 GLQEDQERRRSQEQRRDQKWRWQLEEERKRRRH--------TLYAKPALQEQLRKEQQLL 906
L ++ E+ + ++ +KW EE K + + A+ E+L + +Q L
Sbjct: 1650 KLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKV--EELPQREQNL 1707
Query: 907 QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE-----RERQYR 961
+E+EL +E E E E ++EEE L QEE +L+ E+++ +E RE+
Sbjct: 1708 DWQEKELAQELEELEWDME-ELSWKEEE-LNQEEGKLVEEKKKLAEEEEALAWQREKLSE 1765
Query: 962 KDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYR 1021
++ KL Q+EE L+ E+ ++ Q +EK EEE L ++ EQL+ E++ + Q+ ER
Sbjct: 1766 EETKLAQEEELLIQEK--EKLAQHKEKMPEEEERLGRKREQLI--EKKMKLAQKRERWIN 1821
Query: 1022 KKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLL-GEERETRRRQELERQY 1080
+EL + + L ++ K QE++ +E+E+L Q +E LL +ER T +++L +
Sbjct: 1822 SMEELTKNKMILYQK---KNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVK 1878
Query: 1081 RK-----------EEELQQEEEQLLRE-----EPEKRRRQERERQCREEEELQQEEEQLL 1124
K EE+L QE+E ++++ E EK+ Q + +++E+L QE+ +L
Sbjct: 1879 NKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLA 1938
Query: 1125 REER----EKRRRQELERQYREEE---EVQQEEEQLLR-----------EEPEKRRRQEL 1166
E+ +KR R EL+ E+ E+++ E+ +R E PE R++++
Sbjct: 1939 LEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKM 1998
Query: 1167 ERQYRE--EEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK---RKQRYRDEDQRS 1221
+ +E E +L EE+ LL E++ +E E + E + Q+ + QR + R
Sbjct: 1999 TQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRK 2058
Query: 1222 DLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDL---QHLLGEQQERD 1278
+K + KE A + + + R+L +++ + ++ L + L +Q +
Sbjct: 2059 LIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKL 2118
Query: 1279 REQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKF 1338
+E ++R +E++L R+++K A + R +E+++ EE + R+ E
Sbjct: 2119 DIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDD 2178
Query: 1339 REEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQ 1398
EE + +E L+R+ R RK E R + KF + + E E F +E +
Sbjct: 2179 EEEGGIEEEEVIPFLKRRWRKRK---EAKRGDKPKEKFSSQVDEV---ESEEHFSEEMES 2232
Query: 1399 LRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQE 1458
L + +Q+ + + REEE++ EE++VR +E ERK EE ++ + E
Sbjct: 2233 LLDELEKQESLSSEEEEEREEEEE-----------REEEEVREEEEERKEEEEGEEKQVE 2281
Query: 1459 RHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFL 1518
+ EEE+ +++E+++ QE++ F E+E+ + +E + E+E E E L
Sbjct: 2282 KE----EEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEE----EEESCSL 2333
Query: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDR 1555
EEE R+++ L++E+Q + QE+ ++ + R+R
Sbjct: 2334 EEEVD-----REKEILKKEKQFKLQEQRRKSLRGRER 2365
Score = 157 bits (397), Expect = 1e-37
Identities = 146/645 (22%), Positives = 325/645 (50%), Gaps = 65/645 (10%)
Query: 111 QDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ--SEKQERLEQRDRQR 168
++ QEE + E + EEE +R+K E+E +LA+ EE EK++ + +++
Sbjct: 1733 EELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMP 1792
Query: 169 RDEE-LWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQL--RRRELLELRRKGREE 225
+EE L R+R++ E++ + A++ + + EE + + +++ L + ++ +E
Sbjct: 1793 EEEERLGRKREQLIEKKMKLAQKRERWI---NSMEELTKNKMILYQKKNLAQEKKNLAQE 1849
Query: 226 KQQQRRERQDRVFQEE--------------------------EEKEWRKRETVLRKEEEK 259
K++ + +++ ++ +E EEK +++ETV++K+E+
Sbjct: 1850 KEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKL 1909
Query: 260 LQEEEPQRQRE--LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQE----EE 313
+ E+ Q E L +++E+L + E+ +L E+ Q ++RLR E + ++++ E
Sbjct: 1910 AETEKKLVQVEDSLAKKQEKLAQ-EKMKLALEKAMV-QGKKRLRGELDIAKEEKALNLEM 1967
Query: 314 RREQQEERR-----EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368
+R +E+ R E + E E R++++ + ++E E++L E++ E ++ +
Sbjct: 1968 KRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAME 2027
Query: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ-----LRREQQLRREQ 423
E E + +L + R Q +R+ + +++ + L +E L+ Q+L R++
Sbjct: 2028 ESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDE 2087
Query: 424 QLRREQEEERHEQKHEQERREQRLKREQEER--RDWLKREEETERHEQERRKQQLKRDQE 481
+ ++E + + K +E+RL EQ + ++W E+ +E + E++ + +R
Sbjct: 2088 RKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLA 2147
Query: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE 541
+ R R + EE+ E+ + + ++ E ++ +E L++R R ++ +R
Sbjct: 2148 NKMR-RMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRG 2206
Query: 542 QEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQR 601
+ + + + +E + E E ++ E+++ L EEE R++ +RE+EE
Sbjct: 2207 DKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEE----- 2261
Query: 602 LKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQ--QERREQRL 659
++ EE ER E+EE E+++++EE E++++++ K EE +E+ + +E+ E + L
Sbjct: 2262 VREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESL 2321
Query: 660 KREEEEER---LEQRLKREHEEERREQELAEEEQEQARERIKSRI 701
EEEEE LE+ + RE E ++E++ +EQ + R + R+
Sbjct: 2322 SDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERV 2366
Score = 125 bits (313), Expect = 5e-28
Identities = 121/530 (22%), Positives = 258/530 (48%), Gaps = 63/530 (11%)
Query: 95 LDEEKRARCDGKESLLQDRRQEEDQRR-----------FEPRDRQLEEEPGQ------RR 137
L +EK KE+LL ++ + ++ F Q+EE+ Q ++
Sbjct: 1846 LAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKK 1905
Query: 138 RQKRQEQERELAEGEEQ-SEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSC 196
++K E E++L + E+ ++KQE+L Q + E+ Q ++ E A+EE+ +
Sbjct: 1906 KEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNL 1965
Query: 197 KGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKE 256
+ E E++R E E KG E + R+ + +V QE E++ E +L E
Sbjct: 1966 EMKRLAE----EKMRLVEGKETLSKG-ETPETSRQRKMTQVEQELFERKLSLEEKILLHE 2020
Query: 257 EEKLQEEEPQ----------RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQL 306
+ L EE + QR + + +L K R+ +++ ++ + + + L
Sbjct: 2021 DRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKAL 2080
Query: 307 RRKQEEERREQQEERREQQERREQQEERREQQLRREQ--------EERREQQLRREQEEE 358
++ +ER+ QEE + + +R + R + + + E+R + + E++
Sbjct: 2081 QKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLA 2140
Query: 359 RREQQLRREQEE--ERREQQLRREQQLRREQQ---LRREQQLRREQQ-----LRREQQLR 408
R++++L + + E+ E +L R+ L E++ E++ L+R + R
Sbjct: 2141 RKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKR 2200
Query: 409 REQQLRREQQLRREQQLRREQEEERHEQKHE----QERREQRLKREQEERRDWLKREEET 464
+E + + + + Q+ + EE ++ E + +++ L E+EE +REEE
Sbjct: 2201 KEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEE-----EREEEE 2255
Query: 465 ERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEE--RREQRLKRQ 522
ER E+E R+++ +R +EEE E+ ++ EEEE++++++ ++++ +E+EE ++ + +
Sbjct: 2256 EREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSE 2315
Query: 523 EEEERLQQRLRSEQQLRREQE-ERREQLLKREEEKRLEQERREQRLKREQ 571
EE E L E+ E+E +R +++LK+E++ +L+++RR+ RE+
Sbjct: 2316 EETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRER 2365
Score = 111 bits (278), Expect = 6e-24
Identities = 83/340 (24%), Positives = 169/340 (49%), Gaps = 55/340 (16%)
Query: 113 RRQEEDQRRFEPRDRQLEEEPGQRRR-----QKRQEQERELAEGEEQSEKQER-LEQRDR 166
R+ + R+ + L +EP + + QK ER+L + E + K +R L ++R
Sbjct: 2050 RKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKER 2109
Query: 167 QRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRR---------RELLE 217
+ E+ +EW E+R +E DE++L R R ++
Sbjct: 2110 RLSIEQSKLDIKEWDFSEKR--------------SELTKDEKKLARKQRKLANKMRRMIN 2155
Query: 218 LRRKGREEKQQQRRERQDRVFQEEEE-------------KEWRKRETVLR----KEEEKL 260
K EE+ + R+ + + +EEE + WRKR+ R KE+
Sbjct: 2156 KEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSS 2215
Query: 261 QEEEPQRQRELQEEEEQLR-KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE 319
Q +E + + EE E L +LE+QE +EEE++++ R +EEE RE++E
Sbjct: 2216 QVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEER--------EEEEVREEEE 2267
Query: 320 ERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRR 379
ER+E++E E+Q E+ E++ +++++E+++++++ ++E ++++ E+E E +
Sbjct: 2268 ERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEE 2327
Query: 380 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 419
E+ E+++ RE+++ ++++ + Q+ RR+ RE+ L
Sbjct: 2328 EESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERVL 2367
Score = 50.8 bits (120), Expect = 1e-05
Identities = 42/159 (26%), Positives = 79/159 (49%), Gaps = 39/159 (24%)
Query: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPR--DRQLEEEPGQRRRQKRQEQERELAEGEEQ 154
EE+ R + +E ++ R+EE++R+ E ++Q+E+E +++++K+++++ E+ E EE
Sbjct: 2246 EEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEE- 2304
Query: 155 SEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRE 214
++E+EE +EE ETE DEE+ E
Sbjct: 2305 ------------------------VFEEKEEIMSEE---------ETESLSDEEE--EEE 2329
Query: 215 LLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVL 253
L + EK+ ++E+Q ++ QE+ K R RE VL
Sbjct: 2330 SCSLEEEVDREKEILKKEKQFKL-QEQRRKSLRGRERVL 2367
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 248 bits (634), Expect = 3e-65
Identities = 427/1872 (22%), Positives = 746/1872 (39%), Gaps = 221/1872 (11%)
Query: 100 RARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQE 159
+ RC E L +R E +Q+R + + E R ++ Q++ LA+ +Q
Sbjct: 184 KKRCSELEQQLLERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQVNAMLREQL 243
Query: 160 RLEQRDRQRRDEELWRQRQEW----QEREER----RAEEEQLQSCKGHETEEFPDEEQLR 211
Q E++ + +W +E E R R EEE + +E L
Sbjct: 244 DQAGSANQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAYFSNEHSRL----LLL 299
Query: 212 RRELLELRRKGREEKQQQRRE---------RQDRVFQEEEEKEWRKRETVLRKEEEKLQE 262
R+++ RR E K R+ R R QE T LR E + E
Sbjct: 300 WRQVVGFRRLVSEVKMFTERDLLQLGGELARTSRAVQE----AGLGLSTGLRLAESR-AE 354
Query: 263 EEPQRQRELQEE-EEQLRKLERQELRRERQEEEQQQQ----------RLRREQQLRRKQE 311
++Q LQ + EEQL R ++ RE+ +QQ Q R+ ++ E
Sbjct: 355 AALEKQALLQAQLEEQL----RDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVKRLE 410
Query: 312 EERREQQEERREQQERREQQEERREQQ---LRREQEERREQQLRR-----EQEEERREQQ 363
++ E+ + ++ E+ E E R Q+ L E E +Q LR + E Q
Sbjct: 411 KQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGEGLQQTLRDLAQAVLSDSESGVQL 470
Query: 364 LRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRR--------------EQQLRR 409
E+ + LR R RR R R L +
Sbjct: 471 SGSERTADASNGSLRGLSGQRTPSPPRRSSPGRGRSPRRGPSPACSDSSTLALIHSALHK 530
Query: 410 EQQLRREQQLRRE--QQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERH 467
Q ++ + R E Q L ++ + + E+ E++L+R +++ ++ E+ +R
Sbjct: 531 RQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQRE 590
Query: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEER 527
Q R +E+ L++ +++ E ++ RE +L+ QEE R QR + +EE+E
Sbjct: 591 VQRLRSANELLSREKSNLAHSLQVAQQQAEELRQERE-KLQAAQEELRRQRDRLEEEQE- 648
Query: 528 LQQRLRSEQQLRREQEERREQLLKREEEKR-LEQERREQRLKREQEERRDQLLKREEERR 586
++ ++RRE E QL + E ++ L +E E R + + +L+ E+
Sbjct: 649 --DAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEV 706
Query: 587 QQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLL---KSEEQEERR 643
+ L + + R+E L ++ R E+ ++ K E Q L + Q E
Sbjct: 707 AEALTKAEAGRVELELSMTKL-RAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEE 765
Query: 644 QQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPK 703
+ L+ Q++ ++ EE+ERLE+ L+ E E R+ E + EQA+E ++ ++P
Sbjct: 766 KSALQGRQRQAEQEATVAREEQERLEE-LRLEQEVARQGLEGSLRVAEQAQEALEQQLP- 823
Query: 704 WQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQE-EE 762
L E Q ++ R+ G +EQE ++ RRE++ Q + ERA R+++ +
Sbjct: 824 ---TLRHERSQLQEQLAQLSRQLSG----REQELEQARREAQRQVEALERAAREKEALAK 876
Query: 763 QRRDFTWQWQAEEKSERGRQRLSARPPLR------------------EQRERQLRAE--- 801
+ Q A E+ R + R L E R QL AE
Sbjct: 877 EHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQA 936
Query: 802 ----------ERQQREQRFLPEEE----EKEQRRRQRREREKELQFLEEEEQLQRRERAQ 847
E Q+ + +E +KE ++ + E+E Q E++ E Q
Sbjct: 937 LLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQ 996
Query: 848 QLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQ 907
+LQ E++ + E R+Q Q + Q+ + +L + + L + A +Q R E LL
Sbjct: 997 RLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLA 1056
Query: 908 EEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967
E E++ +E + E+ L ++ R++R+ + RQE++R +
Sbjct: 1057 ESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSE 1116
Query: 968 QKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQ 1027
++ + EE QE + + +L ++ + LRE E R + R D L+
Sbjct: 1117 LRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDAR--DGLR 1174
Query: 1028 QEEEQLLREEREKRRLQE-RERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEEL 1086
+E LL +R+ R QE RE Q +E EL++ + E RR E R K+ E
Sbjct: 1175 RE---LLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAES 1231
Query: 1087 QQEEEQLLREEPEKR---RRQERERQCREEEELQQEEEQLLREEREKRRR-QELERQY-- 1140
++ +L E+ E++ + R +E EL+ +++ R E RR QEL RQ
Sbjct: 1232 ERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKM 1291
Query: 1141 ---------REEEEVQQEEEQLLREEPEKRR-----RQELERQYREEEELQQEEEQLLR- 1185
RE E+Q R E E RR RQ L + E ++QE + R
Sbjct: 1292 LDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRK 1351
Query: 1186 -EEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKG 1244
+EQE + RER+ E R KQ+ D + +LK + + + +G
Sbjct: 1352 LQEQEGEFRTRERRLLGSLEEARGTEKQQL-DHARGLELKLEAARAEAAELGLRLSAAEG 1410
Query: 1245 RENEQFRQLEDSQLRDRQSQQDLQHL---------------------------------L 1271
R +L +++ R ++ L L
Sbjct: 1411 RAQGLEAELARVEVQRRAAEAQLGGLRSALRRGLGLGRAPSPAPRPVPGSPARDAPAEGS 1470
Query: 1272 GEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRD-RKSQEEKQLLREEREEKRR 1330
GE E Q P + EA R R+ +E + + ER+E
Sbjct: 1471 GEGLNSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREFLQELRSAQRERDE--L 1528
Query: 1331 RQETDRKFREEEQLLQEREEQPLRRQERDRKFRE-EELRHQEQGR------KFLEEEQRL 1383
R +T R+ ++ ER+ R ++ + E EE R GR + +E+ +
Sbjct: 1529 RTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESV 1588
Query: 1384 RRQERERKFLKE-----EQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRK--FREEE 1436
RR ERER+ + E+ L+ E E + Q++ K + E +L +R K E
Sbjct: 1589 RRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASE 1648
Query: 1437 QQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRR 1496
+ + E +R+ LE E Q + + Q LQ+R + L RQ D + QL
Sbjct: 1649 SRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVD-SLQRQVADSEVKAGTLQLTV 1707
Query: 1497 QERD---RKFREQELRSQEPERKFLE--EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQ 1551
+ + K E E ++ R E + + K L ++ L E +Q Q
Sbjct: 1708 ERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQ 1767
Query: 1552 DRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQ 1611
+R R+ ++ L Q + + + + +++R E E + + + LR+++ +
Sbjct: 1768 ERLDAARQALS-EARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGE 1826
Query: 1612 QLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFRE 1671
+K +++ +LLQER L +R LE E +R+ LR ++DR
Sbjct: 1827 AAALNTVQKLQDERRLLQER----LGSLQRALAQLEAE---KREVERSALRLEKDRV--A 1877
Query: 1672 EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELE------RKF 1725
+ L + E ++LR E + E+ +L R + E Q + Q+LE +
Sbjct: 1878 LRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQS 1937
Query: 1726 REEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREE 1785
QL + +Q+QL Q+ + L Q + ER + R R R EEQ+ + +
Sbjct: 1938 HSPAQLEVDAQQQQLELQQEVER-LRSAQAQTERTLEARERAHRQRVRGLEEQVSTLKGQ 1996
Query: 1786 QQLRSQESDRKF 1797
Q + S F
Sbjct: 1997 LQQELRRSSAPF 2008
Score = 232 bits (592), Expect = 2e-60
Identities = 391/1618 (24%), Positives = 669/1618 (41%), Gaps = 297/1618 (18%)
Query: 519 LKRQEEEERLQQRL-RSEQQLRREQEERREQLLK-REEEKRLEQERREQRLKREQEERRD 576
L QEE + LQQ L R E L + + ER E +K +RLEQ R + + E +E R
Sbjct: 77 LSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGELETQEPRG 136
Query: 577 QLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKS 636
+ + E RRQ QEE+ R K + + E ++R+ Q ++R + ++L+
Sbjct: 137 LVRQSVELRRQL-----QEEQASYRRKLQAYQ--EGQQRQAQLVQR------LQGKILQY 183
Query: 637 EEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAE------EEQ 690
+++ +QQL E +QRL+ E + LE L R EE++R LA+ E+
Sbjct: 184 KKRCSELEQQLLERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQVNAMLREQL 243
Query: 691 EQA---------------------RERIKSRIPKWQWQLESEADARQSKVYSRP----RK 725
+QA R+ ++ R W+ + ES +A S +SR R+
Sbjct: 244 DQAGSANQALSEDIRKVTNDWTRCRKELEHREAAWRREEES-FNAYFSNEHSRLLLLWRQ 302
Query: 726 QEGQRR------------------------RQEQE------EKRRRRESELQWQEEERAH 755
G RR R QE R ES + E++A
Sbjct: 303 VVGFRRLVSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAALEKQAL 362
Query: 756 RQQQEEEQRRDFTWQ----WQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFL 811
Q Q EEQ RD + Q + +S+ + LSAR + E R E++ + +
Sbjct: 363 LQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSAR--VTELGLAVKRLEKQNLEKDQVN 420
Query: 812 PEEEEKEQRRRQRREREKELQFLEEEEQLQR--RERAQQ-LQEEEDGLQEDQERRR---- 864
+ EK + R +E+ E+ E LQ+ R+ AQ L + E G+Q R
Sbjct: 421 KDLTEKLEALESLRLQEQAALETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSERTADAS 480
Query: 865 -------SQEQRRDQKWRWQLEEERKRRR---------------HTLYAKPALQEQ---- 898
S ++ R R RR H+ K LQ Q
Sbjct: 481 NGSLRGLSGQRTPSPPRRSSPGRGRSPRRGPSPACSDSSTLALIHSALHKRQLQVQDMRG 540
Query: 899 -LRKEQQLLQEEEEELQREEREKRRRQEQERQYREE-------EQLQQEEEQLLREEREK 950
Q LL ++L E E+R +EQ ++ R++ + Q E Q LR E
Sbjct: 541 RYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANEL 600
Query: 951 RRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREERE- 1009
R++ + QQ EE RQEREK +EEL+++ ++L E+ +
Sbjct: 601 LSREKSNLAHSLQVAQQQAEE----------LRQEREKLQAAQEELRRQRDRLEEEQEDA 650
Query: 1010 ----KRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEE--EQL 1063
R R+E ER +R+ ++L+ + L +E E R R R+ + ++ E E L
Sbjct: 651 VQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEAL 710
Query: 1064 LGEE---------------RETRRRQELERQYRKEEELQQEEEQLLR----EEPEKRRRQ 1104
E E + L + E L Q++ L R E EK Q
Sbjct: 711 TKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQ 770
Query: 1105 ERERQCREEEELQQEEEQLLREER--EKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162
R+RQ +E + +EE++ L E R ++ RQ LE R E+ Q+ EQ L P R
Sbjct: 771 GRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQL---PTLRH 827
Query: 1163 RQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQ--- 1219
+ + +E+L Q QL EQE + RE Q R+ E L+R R++ ++
Sbjct: 828 ERS-----QLQEQLAQLSRQLSGREQELEQARREAQ-RQVEALERAAREKEALAKEHAGL 881
Query: 1220 -----RSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQ 1274
++ + + E+ +R K +G E RQL + R Q + + Q LL +
Sbjct: 882 AVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAK 941
Query: 1275 QERDREQERRRWQ--------QRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREERE 1326
+ E R Q D+ ++ ++ E + +A R++++ E+ L R +RE
Sbjct: 942 ETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQRE 1001
Query: 1327 EKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELR--HQEQGRKFL----EEE 1380
++ +E + + + + LQ +E+ L R E +++ EE+ QE+ L E++
Sbjct: 1002 KEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQ 1061
Query: 1381 QRLRRQERERKFLKEE------------QQLRCQEREQQLRQDRDRKFREEEQQLSRQER 1428
Q L +E E+ L E+ ++ Q+R+ Q RQ++D R L+ + R
Sbjct: 1062 QALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQD---RSTVNALTSELR 1118
Query: 1429 DRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERD---R 1485
D + + EE + R+ E+ + L ++R RE E+L R + +L RD R
Sbjct: 1119 DLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEEL---RTQLRLLEDARDGLRR 1175
Query: 1486 KFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQER 1545
+ LE +++LR + R+ + QE + E R E ++ +R + L+ + ER
Sbjct: 1176 ELLEAQRKLRESQEGREVQRQE--AGELRRSLGEGAKEREALRRSNEELRSAVKKAESER 1233
Query: 1546 GQQR--RQDRDRKFREEEQLR----QEREEQQLSRQERDR---KFRLEEQKVRRQEQERK 1596
+ +D+++K E+ R +E E + QE +R + R E Q++RRQ K
Sbjct: 1234 ISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQ---MK 1290
Query: 1597 FMEDE-----QQLRRQEGQQQLRQERDRKFRED-----EQLLQEREEQQLHRQE---RDR 1643
++ E ++L +G+ L + +++ R + ++LL+ ++ RQE R
Sbjct: 1291 MLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQR 1350
Query: 1644 KFLEEEPQLRRQER-------------EQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD 1690
K E+E + R +ER +QQL H R + + E E E LR +
Sbjct: 1351 KLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELK-LEAARAEAAELGLRLSAAE 1409
Query: 1691 RKFREEEQQLRRQERERKFLQEEQQLRRQELERKF---------------REEEQLRQET 1735
+ + E +L R E +R+ + + R L R E
Sbjct: 1410 GRAQGLEAELARVEVQRRAAEAQLGGLRSALRRGLGLGRAPSPAPRPVPGSPARDAPAEG 1469
Query: 1736 EQEQLRRQERYR------------------KILEEEQLRPEREE--QQLRRQERDRKFRE 1775
E L L+ E +R E Q+LR +R+ R+
Sbjct: 1470 SGEGLNSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREFLQELRSAQRE---RD 1526
Query: 1776 EEQLRQEREEQQLRSQESDR--KFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQ 1833
E + + +QL E++R QL++ E + + DG+ + +L L+E+
Sbjct: 1527 ELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEE 1586
Query: 1834 EQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKE 1891
R R ER+R+ +Q AT E+S + + + ++K + + + + E +R+ KE
Sbjct: 1587 SVR-RSERERR-ATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKE 1642
Score = 231 bits (590), Expect = 4e-60
Identities = 433/1893 (22%), Positives = 770/1893 (40%), Gaps = 208/1893 (10%)
Query: 156 EKQERLEQRDRQRRDEELWRQRQEWQEREER-RAEEEQLQSCKGHETEEFPDEEQLRR-R 213
+++ +L Q++ R ++ L + R E E + A E+L+ E E +E R
Sbjct: 80 QEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGELETQEPRGLVR 139
Query: 214 ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273
+ +ELRR+ +EE+ RR+ Q +QE ++++ + ++LQ + Q ++ E
Sbjct: 140 QSVELRRQLQEEQASYRRKLQ--AYQEGQQRQ--------AQLVQRLQGKILQYKKRCSE 189
Query: 274 EEEQLRKLERQ-ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE-QQ 331
E+QL LER EL ++R + + Q L E L R +EE++R + R + Q
Sbjct: 190 LEQQL--LERSGELEQQRLRDTEHSQDL--ESALIRLEEEQQRSASLAQVNAMLREQLDQ 245
Query: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR 391
Q L + + R +E E RE RRE+E + L +Q+
Sbjct: 246 AGSANQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAYFSNEHSRLLLLWRQVVG 305
Query: 392 EQQLRREQQLRREQQLRR-EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKRE 450
++L E ++ E+ L + +L R + +E L E + E +Q L +
Sbjct: 306 FRRLVSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQA 365
Query: 451 Q--EERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLR 508
Q E+ RD + RE++ +Q+ + K D E L ++ R E+Q + Q+
Sbjct: 366 QLEEQLRDKVLREKDLA--QQQMQSDLDKADLSARVTELGLAVK---RLEKQNLEKDQVN 420
Query: 509 REQEERREQ----RLKRQ-----EEEERLQQRLRSEQQLRREQEERREQLL--KREEEKR 557
++ E+ E RL+ Q E+ E LQQ LR Q E QL +R +
Sbjct: 421 KDLTEKLEALESLRLQEQAALETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSERTADAS 480
Query: 558 LEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERRE 617
R + RR + RR L +L+ ++ R
Sbjct: 481 NGSLRGLSGQRTPSPPRRSSPGRGRSPRRGPSPACSDSSTLALIHSALHKRQLQVQDMRG 540
Query: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHE 677
+ ++ R+QL SE + ++QL+R +++ + ++ E+ +R QRL+ +E
Sbjct: 541 RYEASQDLLGTLRKQLSDSESERRALEEQLQR-LRDKTDGAMQAHEDAQREVQRLRSANE 599
Query: 678 EERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEE 737
RE+ + A+++ + E + K+ + + QR R E+E+
Sbjct: 600 LLSREKSNLAHSLQVAQQQAE------------ELRQEREKLQAAQEELRRQRDRLEEEQ 647
Query: 738 KRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGR---QRLSARPPLREQR 794
+ ++ +E ER+HRQ ++ E +R + E + R QR + E
Sbjct: 648 EDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVA 707
Query: 795 ERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEED 854
E +AE + + + + +E + + L +++L QL+EE+
Sbjct: 708 EALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKS 767
Query: 855 GLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQ 914
LQ ++R+ QE ++ + +LEE R + A+ L+ LR +Q + E++L
Sbjct: 768 ALQ-GRQRQAEQEATVAREEQERLEELRLEQE---VARQGLEGSLRVAEQAQEALEQQLP 823
Query: 915 REEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEE--- 971
E+ + QEQ Q QL E++L + RE +R+ E + ++K+ KE
Sbjct: 824 TLRHERSQLQEQLAQL--SRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGL 881
Query: 972 --QLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE 1029
QL+ E E R E + R E+E E L +R+ + + ++++L+ E
Sbjct: 882 AVQLVAAEREGRTLSEEATRLRLEKEAL--EGSLFEVQRQLAQLEA------RREQLEAE 933
Query: 1030 EEQLL-REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQ 1088
+ LL +E L +Q +E +++L+ ++ R E + R++ +
Sbjct: 934 GQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAER-EAQASLREQRAAHE 992
Query: 1089 EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLL-REEREKRRRQELERQYREEEEVQ 1147
E+ Q L+ E E R+ + + + +LQ+E+E+LL R E EK E E +Q
Sbjct: 993 EDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSE------EIAALQ 1046
Query: 1148 QE-EEQLLREEPEKRRRQELERQYRE--EEELQQEEEQLLREEQEKRRQERERQYREEEE 1204
QE +E LL E EK++ L+ + E+L L E RQ+R+ Q R+E
Sbjct: 1047 QERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQE-- 1104
Query: 1205 LQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQL---EDSQLRDR 1261
Q R + DL+ Q E ++ + R EQ R L DS LR+
Sbjct: 1105 ---QDRSTVNALTSELRDLRAQREEAAAAHAQEVR-----RLQEQARDLGKQRDSCLREA 1156
Query: 1262 QSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLL 1321
+ + LL + ++ R +E Q++ R E +++R+E E +R + +E++ L
Sbjct: 1157 EELRTQLRLLEDARDGLR-RELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREAL 1215
Query: 1322 REEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRH-----QEQGRKF 1376
R EE R + R +L E +EQ L E R +E QE R
Sbjct: 1216 RRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSR 1275
Query: 1377 LEEEQRLRRQERERKFL-KEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFR-E 1434
LE + L+ R+ K L E +L + E Q R + +E ++ + R R + E
Sbjct: 1276 LEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGE 1335
Query: 1435 EEQQVRRQE---RERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEE 1491
+V RQE +RK E+E + R R E+ ++Q H + + K E
Sbjct: 1336 ASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKL--EA 1393
Query: 1492 QQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQ----RKFLQEEQQLRRQERGQ 1547
+ E + E R+Q E + E Q + Q R L+ L R
Sbjct: 1394 ARAEAAELGLRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLRSALRRGLGLGRAPSPA 1453
Query: 1548 QR----RQDRDRKFREEEQLRQEREEQQLSRQER---------DRKFRLEEQKVRRQEQE 1594
R RD + + S + L+ + VR +E
Sbjct: 1454 PRPVPGSPARDAPAEGSGEGLNSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALRE 1513
Query: 1595 -----RKFMEDEQQLRRQEGQ-----QQLRQERDRKFREDEQLLQEREEQQLHRQERDRK 1644
R + +LR Q ++ ERD QL + E + R+ D +
Sbjct: 1514 FLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGR 1573
Query: 1645 FLEEEPQLRRQEREQQLRHDRDRKFREE-----EQLLQEGEEQQLRRQERDRKFREEEQQ 1699
+ +L QE E R +R+R+ + E+ LQ E + QE+ K + E +
Sbjct: 1574 LSGVQAELALQE-ESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETK 1632
Query: 1700 LRRQERERKFLQEEQQLR--RQELERKFREEEQLR-----QETEQEQLRRQER----YRK 1748
L +R K + + + R + EL+R+ E E R + E + Q+R R+
Sbjct: 1633 LEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQ 1692
Query: 1749 ILEEE------QLRPEREEQQLRRQE------RDRKFREEEQLRQ------EREEQQLRS 1790
+ + E QL ER L + E RD+ E L Q ++ L
Sbjct: 1693 VADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHL 1752
Query: 1791 QESDRKFREEEQLRQER--------------------EEQQLRPQQRDGKYRWEEEQLQL 1830
Q++ + Q+ QER + Q LR + D + + E + QL
Sbjct: 1753 QKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQL 1812
Query: 1831 EEQEQRLRQERDRQYRA--------EEQFATQEKSRREEQELWQEEEQKR-------RQE 1875
++ + LRQ ++ + A +E+ QE+ ++ L Q E +KR R E
Sbjct: 1813 QQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLE 1872
Query: 1876 RERKLREEHIRRQQKEEQR-HRQVGEIKSQEGK 1907
++R + + ++E+ R H + +++G+
Sbjct: 1873 KDRVALRRTLDKVEREKLRSHEDTVRLSAEKGR 1905
Score = 211 bits (537), Expect = 6e-54
Identities = 350/1460 (23%), Positives = 615/1460 (42%), Gaps = 232/1460 (15%)
Query: 633 LLKSEEQEERRQQQLRR-------EQQERREQRLKREEEEERLEQRLKREHEE-ERREQE 684
LL +E+ + QQ+L R + ER E +K ERLEQ L+ E E E +E
Sbjct: 76 LLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGELETQEPR 135
Query: 685 LAEEEQEQARERIKSRIPKWQWQLES--EADARQSKVYSRPRKQ--EGQRRRQEQEEKRR 740
+ + R +++ ++ +L++ E RQ+++ R + + + ++R E E++
Sbjct: 136 GLVRQSVELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLL 195
Query: 741 RRESELQWQE-EERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLR 799
R EL+ Q + H Q E R EE+ +R LREQ ++
Sbjct: 196 ERSGELEQQRLRDTEHSQDLESALIR-------LEEEQQRSASLAQVNAMLREQLDQAGS 248
Query: 800 AEERQQREQRFLPEEEEKEQRRRQRRE----REKE---LQFLEEEEQL----------QR 842
A + + R + + + ++ + RE RE+E F E +L +R
Sbjct: 249 ANQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAYFSNEHSRLLLLWRQVVGFRR 308
Query: 843 RERAQQLQEEEDGLQEDQERRRS----QEQRRDQKWRWQLEEERKRRRHTLYA--KPALQ 896
++ E D LQ E R+ QE +L E R A + L+
Sbjct: 309 LVSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLE 368
Query: 897 EQLR----KEQQLLQEE-EEELQREEREKRRRQ------EQERQYREEEQLQQEEEQLLR 945
EQLR +E+ L Q++ + +L + + R + E+Q E++Q+ ++ + L
Sbjct: 369 EQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLE 428
Query: 946 EEREKRRRQERERQYRKDKKLQQ--------------KEEQLLGEE-------------- 977
R +++ + + LQQ QL G E
Sbjct: 429 ALESLRLQEQAALETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSERTADASNGSLRGLS 488
Query: 978 ------PEKRRRQEREKKYREEEELQQEEEQ---LLREEREKRRRQEWERQYR---KKDE 1025
P +R R + R + L+ KR+ Q + + R +D
Sbjct: 489 GQRTPSPPRRSSPGRGRSPRRGPSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDL 548
Query: 1026 LQQEEEQLLREEREKRRLQERERQYREEEE--LQQEEEQLLGEERETRRRQELERQYRKE 1083
L +QL E E+R L+E+ ++ R++ + +Q E+ +RE +R + +E
Sbjct: 549 LGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHED----AQREVQRLRSANELLSRE 604
Query: 1084 EELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREERE-----KRRRQELER 1138
+ Q+ +++ E+ RQERE+ +EEL+++ ++L E+ + R R+ELER
Sbjct: 605 KSNLAHSLQVAQQQAEE-LRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELER 663
Query: 1139 QYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQ 1198
+R+ E+++ + L +E E R+ L R + + LQ E+ + + E K R
Sbjct: 664 SHRQLEQLEGKRSVLAKELVEV--REALSRATLQRDMLQAEKAE-VAEALTKAEAGR--- 717
Query: 1199 YREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED--S 1256
EL+ K R + + L K +A+ ++ K N QLE+ S
Sbjct: 718 ----VELELSMTKLRAEEASLQDSL------SKLSALNESLAQDKLDLNRLVAQLEEEKS 767
Query: 1257 QLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE------EEQLEREEQKEAKRR 1310
L+ RQ Q + Q ++E++R +E R Q+ R E E+ E EQ+ R
Sbjct: 768 ALQGRQRQAE-QEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLR 826
Query: 1311 DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEE---- 1366
+SQ ++QL + R+ R QE ++ RE +R+ + L R R+++ +E
Sbjct: 827 HERSQLQEQLAQLSRQLSGREQELEQARRE-----AQRQVEALERAAREKEALAKEHAGL 881
Query: 1367 ----LRHQEQGRKFLEEEQRLRRQERERK---FLKEEQQLRCQEREQQLRQDRDRKF--- 1416
+ + +GR EE RLR ++ + F + Q + + R +QL +
Sbjct: 882 AVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAK 941
Query: 1417 ----------------REEEQQLSRQERDRKFREEEQQVRRQERERKFLEEE--QQLRQE 1458
+E+ L ++ +K + E++ + RE++ EE Q+L++E
Sbjct: 942 ETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQRE 1001
Query: 1459 RHRKFREEE-------QLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKF------RE 1505
+ +RE E LQ +E+ L R E +++ L EE +QERD ++
Sbjct: 1002 KEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQ 1061
Query: 1506 QELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRK-----FREE 1560
Q L +E E+ L E+ R L+ E RQ+R Q RQ++DR E
Sbjct: 1062 QALSLKESEKTALSEKLMGTRHSLATISLEME----RQKRDAQSRQEQDRSTVNALTSEL 1117
Query: 1561 EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD-- 1618
LR +REE + + R RL+EQ +Q + + ++LR Q + L RD
Sbjct: 1118 RDLRAQREEAAAAHAQEVR--RLQEQARDLGKQRDSCLREAEELRTQ--LRLLEDARDGL 1173
Query: 1619 -RKFREDEQLLQEREE-QQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLL 1676
R+ E ++ L+E +E +++ RQE +LRR E +R+ R E+L
Sbjct: 1174 RRELLEAQRKLRESQEGREVQRQEAG--------ELRRSLGEG--AKEREALRRSNEELR 1223
Query: 1677 QEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE 1736
++ + R ++EQ+L E R + +E EL +E E+ R E
Sbjct: 1224 SAVKKAESERISLKLANEDKEQKLALLEEARTAVGKE----AGELRTGLQEVERSRLEAR 1279
Query: 1737 QEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQERE-EQQLRSQESDR 1795
+E L+ R K+L+ E R RE +L+ + + E+E R+ Q+L E+
Sbjct: 1280 RE-LQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASL 1338
Query: 1796 KFREEEQLRQEREEQQLRPQQRDGKYRWEEEQL--QLEEQEQRLRQERDRQYRAEEQFAT 1853
E +RQE + Q + Q+++G++R E +L LEE +Q+ D E +
Sbjct: 1339 -----EVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKL-- 1391
Query: 1854 QEKSRREEQELW--QEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKS--QEGKGH 1909
E +R E EL + R Q E +L ++R+ E Q+G ++S + G G
Sbjct: 1392 -EAARAEAAELGLRLSAAEGRAQGLEAELARVEVQRRAAE----AQLGGLRSALRRGLGL 1446
Query: 1910 GRLLEPGTHQFASVPVRSSP 1929
GR P P R +P
Sbjct: 1447 GRAPSPAPRPVPGSPARDAP 1466
Score = 202 bits (513), Expect = 3e-51
Identities = 340/1375 (24%), Positives = 581/1375 (42%), Gaps = 197/1375 (14%)
Query: 107 ESLLQDRRQEEDQRRF------EPRDRQLEEEPGQRRRQKRQ-------EQERELAEGEE 153
E LL R E D+ E ++ L EPG+ Q+ + E R+L E +
Sbjct: 94 EDLLAQSRAERDELAIKYNAVSERLEQALRLEPGELETQEPRGLVRQSVELRRQLQEEQA 153
Query: 154 QSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQ--------LQSCKGHETEEFP 205
++ + Q +QR+ + + R + + + ++R +E EQ L+ + +TE
Sbjct: 154 SYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRDTEHSQ 213
Query: 206 D---------EEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEK---EWRKRETVL 253
D EEQ R L ++ RE+ Q Q E+ K +W + L
Sbjct: 214 DLESALIRLEEEQQRSASLAQVNAMLREQLDQAGSANQ--ALSEDIRKVTNDWTRCRKEL 271
Query: 254 RKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEE 313
E + EE E +L L RQ + R E + R QL +
Sbjct: 272 EHREAAWRREEESFNAYFSNEHSRLLLLWRQVVGFRRLVSEVKMFTERDLLQLGGELART 331
Query: 314 RREQQEERREQQERREQQEERREQQLRREQ--EERREQQLRRE--QEEERREQQLRREQE 369
R QE E R E L ++ + + E+QLR + +E++ +QQ++ + +
Sbjct: 332 SRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLD 391
Query: 370 E---ERREQQLRREQQLRREQQLRREQQLR-REQQLRREQQLRREQQLRRE-------QQ 418
+ R +L + +Q L ++Q + ++L + LR ++Q E QQ
Sbjct: 392 KADLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGEGLQQ 451
Query: 419 LRREQQLRREQEEERHEQKHEQERREQ----RLKREQEERRDWLKREEETERHEQERR-- 472
R+ + E Q ER L+ +R R R RR
Sbjct: 452 TLRDLAQAVLSDSESGVQLSGSERTADASNGSLRGLSGQRTPSPPRRSSPGRGRSPRRGP 511
Query: 473 ------------------KQQLK----RDQEEERRERWLKLEEEERREQQERR--EQQLR 508
K+QL+ R + E ++ L ++ + ERR E+QL+
Sbjct: 512 SPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQ 571
Query: 509 REQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLK 568
R ++ + ++ E+ +R QRLRS +L ++ L+ +++ E + ++L+
Sbjct: 572 R-LRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQ 630
Query: 569 REQEERRDQLLKREEERRQQRLKREQEERLEQRLK-REEVER----LEQEERREQRLKRE 623
QEE R R++ RL+ EQE+ ++ + R E+ER LEQ E + L +E
Sbjct: 631 AAQEELR---------RQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKE 681
Query: 624 EPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQ 683
E R+ L ++ Q + L+ E+ E E K E LE + + EE Q
Sbjct: 682 LVEV--REALSRATLQRD----MLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQ 735
Query: 684 E----LAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKR 739
+ L+ + A++++ + + QLE E A Q + R +QE R+EQE
Sbjct: 736 DSLSKLSALNESLAQDKLD--LNRLVAQLEEEKSALQGR--QRQAEQEATVAREEQE--- 788
Query: 740 RRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLR 799
R EL+ ++E RQ E R AE+ E Q+L P LR +R QL+
Sbjct: 789 --RLEELRLEQE--VARQGLEGSLR-------VAEQAQEALEQQL---PTLRHERS-QLQ 833
Query: 800 AEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERA----QQLQEEEDG 855
E+ Q ++ E+E EQ RR+ + + + L+ E++ +E A Q + E +G
Sbjct: 834 -EQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREG 892
Query: 856 LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQR 915
R S+E R + + LE + L A +EQL E Q L +E L
Sbjct: 893 ------RTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTG 946
Query: 916 EEREKRRR--QEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQL 973
E R++ QE+ ++E + Q +L++ ERE + +E++
Sbjct: 947 ELAGLRQQIIATQEKASLDKELMAQ---KLVQAERE--------------AQASLREQRA 989
Query: 974 LGEEPEKRRRQEREKKYRE-EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQ 1032
EE +R ++E+E +RE E E Q + QL RE+ E R E E K+EL +E
Sbjct: 990 AHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAE-----KEELSEEIAA 1044
Query: 1033 LLREEREKRRLQERERQYR---EEEELQQEEEQLLGEERETRR-RQELERQYRKEEELQQ 1088
L +E E L E E+Q +E E E+L+G E+ERQ R + Q+
Sbjct: 1045 LQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQE 1104
Query: 1089 EEE---QLLREEPEKRRRQERERQCREEEELQQEEEQL--LREEREK--RRRQELERQYR 1141
++ L E R Q E +E+++ +EQ L ++R+ R +EL Q R
Sbjct: 1105 QDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLR 1164
Query: 1142 EEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYRE 1201
E+ + + L RE E +R+ R+ +E E+Q++E LR + +ERE R
Sbjct: 1165 LLEDAR---DGLRRELLEAQRKL---RESQEGREVQRQEAGELRRSLGEGAKEREALRRS 1218
Query: 1202 EEELQRQKRKQRYRDEDQRSDLKWQWE-PEKENAVRDNKVYCKGRENEQFRQ-LEDSQLR 1259
EEL+ +K E +R LK E E++ A+ + G+E + R L++ +
Sbjct: 1219 NEELRSAVKKA----ESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERS 1274
Query: 1260 DRQSQQDLQHLLGEQQERDREQER--RRWQQRDRHFPEEEQLEREEQKEA---KRRDRKS 1314
+++++LQ L + + D E R R + E+ E+E ++E ++R K
Sbjct: 1275 RLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKG 1334
Query: 1315 QEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRH 1369
+ +++R+E Q RK +E+E + RE + L E R +++L H
Sbjct: 1335 EASLEVMRQE------LQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDH 1383
Score = 86.7 bits (213), Expect = 2e-16
Identities = 173/766 (22%), Positives = 309/766 (40%), Gaps = 89/766 (11%)
Query: 93 TGLDEEKRARCDGKESLLQDRRQEEDQRRFEPR-DRQLEEEPGQRRRQKRQEQE------ 145
TGL E +R+R + + L + RRQ + R R+L E G+ +R E+E
Sbjct: 1266 TGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETL 1325
Query: 146 ---RELAEGEEQSE--KQE-RLEQRDRQRRDEEL-WRQRQEWQEREERR-AEEEQLQSCK 197
+ L +GE E +QE ++ QR Q ++ E R+R+ EE R E++QL +
Sbjct: 1326 GLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHAR 1385
Query: 198 GHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRK-- 255
G E + + L +GR + + R + V + E + + LR+
Sbjct: 1386 GLELKLEAARAEAAELGLRLSAAEGRAQGLEAELARVE-VQRRAAEAQLGGLRSALRRGL 1444
Query: 256 -------EEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQL-- 306
+ P R + E L E Q L
Sbjct: 1445 GLGRAPSPAPRPVPGSPARDAPAEGSGEGLNSPSTLECSPGSQPPSPGPATSPASPDLDP 1504
Query: 307 ---RRKQEEERREQQEERREQQERREQ----QEERREQQLRREQEERREQQLRR---EQE 356
R E +E + +RE+ E R Q + E + R+ R +QL++ E E
Sbjct: 1505 EAVRGALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESE 1564
Query: 357 EERREQQLRR---EQEEERREQQLRREQQLRR---EQQLRREQQLRREQQLRREQQLRRE 410
E RR R + E +E+ +RR ++ RR +Q E+ L+ + R Q +
Sbjct: 1565 EARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKIS 1624
Query: 411 QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE 470
+ E +L +++ +E + + + E + + L+ E + R L E + Q+
Sbjct: 1625 KMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQD 1684
Query: 471 RRKQQLKRDQEEERRERWL------------KLEEEE--RREQQERREQQLRREQEERRE 516
R ++ + E + L K+EE E R++ + L +
Sbjct: 1685 RVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNS 1744
Query: 517 QRLKR----------QEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERRE-Q 565
R K + + + LQ+RL + +Q E ++ L ++ + R E E Q
Sbjct: 1745 TRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQ 1804
Query: 566 RLKRE-QEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE 624
R++ E Q ++ ++L++ +E L Q+ + E+RL + ERL +R +L+ E+
Sbjct: 1805 RVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQ---ERLGSLQRALAQLEAEK 1861
Query: 625 PEEERRQQLLKSEEQEERRQ-QQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQ 683
E ER L+ + RR ++ RE+ E ++ E+ RL++ L E Q
Sbjct: 1862 REVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQ 1921
Query: 684 ELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRE 743
++ + Q +S P QLE +A +Q ++ +QE +R R Q + R E
Sbjct: 1922 RQIQQLEAQVVVLEQSHSPA---QLEVDAQQQQLEL-----QQEVERLRSAQAQTERTLE 1973
Query: 744 SELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPP 789
+ ERAHRQ+ + + T + Q +++ R S PP
Sbjct: 1974 A------RERAHRQRVRGLEEQVSTLKGQLQQELRRSSAPFS--PP 2011
Score = 75.9 bits (185), Expect = 4e-13
Identities = 114/501 (22%), Positives = 209/501 (41%), Gaps = 75/501 (14%)
Query: 1446 RKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFRE 1505
R+FL+E + ++ER + L ++ E + R + + ++ + E R+ +
Sbjct: 1512 REFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVD 1571
Query: 1506 QELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQ 1565
L + E +E+ + R +R+R+ + Q+ ER Q + + + +E+ +
Sbjct: 1572 GRLSGVQAELAL--QEESVRRSERERRATLD--QVATLERSLQATES-ELRASQEKISKM 1626
Query: 1566 EREEQQLSRQERDRKFRLE--EQKVRRQEQERKFMEDEQQLRR-----QEGQQQLRQER- 1617
+ E +L +R K L+ E + + E +R+ +E E Q R +E Q Q Q+R
Sbjct: 1627 KANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRV 1686
Query: 1618 ---DRKFREDE------QLLQEREEQQLHRQERDRKFLEE-------------------- 1648
R+ + E QL ER L + E L +
Sbjct: 1687 DSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTR 1746
Query: 1649 EPQLRRQEREQQLRHDR---DRKFREEEQLLQEGEEQQLRRQERDRKFREE--EQQLRRQ 1703
+ L Q+ HDR + Q L E +Q E+ + R E + +L+R
Sbjct: 1747 DKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRV 1806
Query: 1704 ERERKFLQEEQQLR-RQELE-------RKFREEEQLRQE---TEQEQLRRQERYRKILEE 1752
E E + Q + LR RQE E +K ++E +L QE + Q L + E ++ +E
Sbjct: 1807 EAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVER 1866
Query: 1753 EQLRPEREEQQLRRQ----ERDRKFREEEQLRQEREEQQLRSQESDRKF--REEEQLRQE 1806
LR E++ LRR ER++ E+ +R E+ +L DR E E +
Sbjct: 1867 SALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRL-----DRTLTGAELELAEAQ 1921
Query: 1807 REEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQE------RDRQYRAEEQFATQEKSRRE 1860
R+ QQL Q + QL+++ Q+Q+L + R Q + E +E++ R+
Sbjct: 1922 RQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAHRQ 1981
Query: 1861 EQELWQEEEQKRRQERERKLR 1881
+E+ + + +++LR
Sbjct: 1982 RVRGLEEQVSTLKGQLQQELR 2002
Score = 68.9 bits (167), Expect = 4e-11
Identities = 105/463 (22%), Positives = 198/463 (42%), Gaps = 77/463 (16%)
Query: 1515 RKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR 1574
R+FL+E L QR+R L+ + ++ + + RD QL++ E + +R
Sbjct: 1512 REFLQE---LRSAQRERDELRTQTSALNRQLAEMEAE-RDSATSRARQLQKAVAESEEAR 1567
Query: 1575 QERDRKFR-------LEEQKVRRQEQERKFMED-----EQQLRRQEGQQQLRQERDRKFR 1622
+ D + L+E+ VRR E+ER+ D E+ L+ E + + QE+ K +
Sbjct: 1568 RSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMK 1627
Query: 1623 EDEQLLQ----------EREEQQLHRQERDRKFLEEEPQLRR---QEREQQLRHDRDRKF 1669
+E L+ + E + + E R+ LE E Q R +RE Q + +DR
Sbjct: 1628 ANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVD 1687
Query: 1670 REEEQLLQEGEEQQLRRQERDR------KFREEEQQLRRQER----------------ER 1707
+ Q+ + + +R K E E LR + R
Sbjct: 1688 SLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRD 1747
Query: 1708 KFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEE--QLRPEREEQQLR 1765
K L ++ L E +R+ +E R + ++ L + L E+ LR E + +L+
Sbjct: 1748 KNLHLQKALTACEHDRQVLQE---RLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQ 1804
Query: 1766 RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQER--EEQQLRPQQRDGKYRW 1823
R E + + ++ ++ ++R+E + + + +K ++E +L QER Q+ Q K
Sbjct: 1805 RVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREV 1864
Query: 1824 EEEQLQLEEQEQRLRQERDR----QYRAEEQFA--TQEKSRREE----QELWQEEEQKRR 1873
E L+LE+ LR+ D+ + R+ E + EK R + EL E Q++
Sbjct: 1865 ERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQI 1924
Query: 1874 QERERK---LREEH------IRRQQKEEQRHRQVGEIKSQEGK 1907
Q+ E + L + H + QQ++ + ++V ++S + +
Sbjct: 1925 QQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQ 1967
Score = 39.3 bits (90), Expect = 0.038
Identities = 43/175 (24%), Positives = 79/175 (45%), Gaps = 13/175 (7%)
Query: 1775 EEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLR----PQQRDGKYRWEEEQLQL 1830
E L +EE QL QE R Q R ER+E ++ ++ + R E +L+
Sbjct: 72 EMASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGELET 131
Query: 1831 EEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERER---KLREEHIRR 1887
+E +RQ + + + +E ++ S R + + +QE +Q++ Q +R K+ + R
Sbjct: 132 QEPRGLVRQSVELRRQLQE----EQASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRC 187
Query: 1888 QQKEEQRHRQVGEIKSQEGKG--HGRLLEPGTHQFASVPVRSSPLYEYIQEQRSQ 1940
+ E+Q + GE++ Q + H + LE + RS+ L + R Q
Sbjct: 188 SELEQQLLERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQVNAMLREQ 242
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 238 bits (608), Expect = 3e-62
Identities = 179/668 (26%), Positives = 362/668 (54%), Gaps = 91/668 (13%)
Query: 583 EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642
+E RQ +L +E+ + + + +++++ E S E E++
Sbjct: 53 KETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQK 112
Query: 643 ----RQQQLRREQQER--------------------REQRLKREEEEERLEQRLKREHEE 678
Q+ LRRE + + + +K+ E E R + R H+
Sbjct: 113 ASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEAR--DLISRLHDS 170
Query: 679 ERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEK 738
+ EL + A + K + ++ +L E DA ++Y E E +EK
Sbjct: 171 WKFAGELEQALSAVATQ--KKKADRYIEELTKERDALSLELYRNTITDE------ELKEK 222
Query: 739 RRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQL 798
+ + +LQ E E++ Q +E +R K ER + L P + Q E
Sbjct: 223 NAKLQEKLQLVESEKSEIQLNVKELKR----------KLERAKLLL---PQQQLQAEADH 269
Query: 799 RAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQE 858
+E Q + + EE E R +++E+++ +EE++Q E +++QE+E+ ++E
Sbjct: 270 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW--RQEEKIQEWE--EKIQEQEEKIRE 325
Query: 859 DQERRRSQEQ--RRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQRE 916
+E+ R QE+ RR ++ W+ EE+ +R+ ++ K +E++R+ ++++ E+EE++ RE
Sbjct: 326 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK---EEKMRRLEEMMWEKEEKI-RE 381
Query: 917 EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERE-RQYRKDKKLQQKEEQLLG 975
EK QE+ RE+E+ +QEEE++ RE+ +RQE+E + +R+++K++++EE++
Sbjct: 382 LEEKMHEQEK---IREQEEKRQEEEKI----REQEKRQEQEAKMWRQEEKIREQEEKIRE 434
Query: 976 EEPEKRRRQER---EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQ 1032
+E + R++E+ ++K REEE+ Q++EE +EE+ + + + W R+K+++ ++E+
Sbjct: 435 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW----RQKEKMHEQEKI 490
Query: 1033 LLREE---REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQE 1089
+EE R++ ++ ++E + RE+EE +E+ + E+ E R QE + R++EE+ QE
Sbjct: 491 RKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQE--EKIREQEEMMQE 548
Query: 1090 EEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQE 1149
+E+ + E+ EK + QE+ R R+EE+++++EE+ +RE++EK R QE E+ + +EE+++++
Sbjct: 549 QEEKMGEQEEKMQEQEKMR--RQEEKIREQEEK-IREQKEKIREQE-EKIWEQEEKIREQ 604
Query: 1150 EEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK 1209
EE + QE E + E+EE E+E+ ++E++EK R++ E+ + +E L++Q+
Sbjct: 605 EEMM----------QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 654
Query: 1210 RKQRYRDE 1217
K + E
Sbjct: 655 EKMQEHQE 662
Score = 235 bits (600), Expect = 3e-61
Identities = 173/600 (28%), Positives = 334/600 (55%), Gaps = 98/600 (16%)
Query: 812 PEEEEKEQRRRQ---RREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQ 868
PE+E+K + Q RRE E ++ + Q+ E L + +++ + R
Sbjct: 107 PEDEQKASHQHQEALRRELEAQVHTIRILT-CQKTELQMALYYSQHAVKQLEGEARDLIS 165
Query: 869 RRDQKWRW-----------------------QLEEERKRRRHTLYAKPALQEQLRKEQ-- 903
R W++ +L +ER LY E+L+++
Sbjct: 166 RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 225
Query: 904 -----QLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE------------ 946
QL++ E+ E+Q +E +R+ E+ + ++QLQ E + L +E
Sbjct: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
Query: 947 -ERE---KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQ 1002
E E + +Q+ E+ +R+++K+Q+ EE++ +E + R E+E+K RE+EE + +E+
Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR---EQEEKIREQEEKMRRQEE 342
Query: 1003 LLREEREKRRRQE---WERQ--YRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQ 1057
++ E+ EK RRQE WE++ R+ +E+ E+E+ +RE EK QE+ RE+EE +
Sbjct: 343 MMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK---IREQEEKR 399
Query: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117
QEEE++ RE +RQE E + ++EE +E+E+ +RE+ +K RQ E + E+E+++
Sbjct: 400 QEEEKI----REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ--EEKIHEQEKIR 453
Query: 1118 QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQ 1177
+EE+ R+E+E+ RQ E + RE+EE+ +++E++ E EK R+QE E+ +R+EE++
Sbjct: 454 EEEK---RQEQEEMWRQ--EEKIREQEEIWRQKEKM--HEQEKIRKQE-EKVWRQEEKMH 505
Query: 1178 QEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRD 1237
+EE++ R++ E+ +R+EE+++ Q+ K R ++E R + E E++ ++
Sbjct: 506 DQEEKI--------REQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQE 557
Query: 1238 NKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEE 1297
K+ +E E+ R+ E+ ++R+++ + + EQ+E+ REQE + W+Q ++ +EE
Sbjct: 558 EKM----QEQEKMRRQEE-KIREQEEK------IREQKEKIREQEEKIWEQEEKIREQEE 606
Query: 1298 QLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQE 1357
++ +E+K ++ ++ ++E+++ +E+EEK RRQE K E+E L+++EE+ QE
Sbjct: 607 MMQEQEEKMWEQEEKMCEQEEKM--QEQEEKMRRQE--EKMWEQEVRLRQQEEKMQEHQE 662
Score = 235 bits (599), Expect = 4e-61
Identities = 181/685 (26%), Positives = 354/685 (51%), Gaps = 88/685 (12%)
Query: 434 HEQKHEQERREQRLKREQEERRDWLKREEETERHEQ----------ERRKQQLKRDQEEE 483
H H + +E + + +E+ T+ H Q + +K+++ E
Sbjct: 38 HLPTHPHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPE 97
Query: 484 RRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQE 543
E+ ++ + ++ LRRE E + ++ LQ L Q ++ E
Sbjct: 98 TTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLE 157
Query: 544 ERREQLLKREEEK-----RLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE---QE 595
L+ R + LEQ ++++ +R + L +E + L R E
Sbjct: 158 GEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE 217
Query: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEE-RRQQLLKSEEQEERRQQQLRREQQER 654
E E+ K +E +L + E+ E +L +E + + R +LL ++Q + L +E Q
Sbjct: 218 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 277
Query: 655 REQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADA 714
+L+ + EE L RL ++ EE+ QE +I +W+ +++ + +
Sbjct: 278 -SAKLQAQVEENELWNRLNQQQEEKMWRQE--------------EKIQEWEEKIQEQEE- 321
Query: 715 RQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQ-----EEEQRRDFTW 769
+ +E + + +EQEEK RR+E E+ W++EE+ RQ++ EE+ RR
Sbjct: 322 ---------KIREQEEKIREQEEKMRRQE-EMMWEKEEKMRRQEEMMWEKEEKMRRLEEM 371
Query: 770 QWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREK 829
W+ EEK +++ + +REQ EE++Q E++ +E+ +EQ + R+ EK
Sbjct: 372 MWEKEEKIRELEEKMHEQEKIREQ-------EEKRQEEEKIREQEKRQEQEAKMWRQEEK 424
Query: 830 ELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTL 889
E+EE+++ +E+ QEE+ +QE+ R +E+R++Q+ W+ EE+ + +
Sbjct: 425 ---IREQEEKIREQEKKMWRQEEKI---HEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 478
Query: 890 YAKPAL--QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREE 947
K + QE++RK+++ + +EE++ ++E++ R+++E+ +R+EE+++++EE++ RE+
Sbjct: 479 RQKEKMHEQEKIRKQEEKVWRQEEKMH--DQEEKIREQEEKMWRQEEKIREQEEKI-REQ 535
Query: 948 REKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREE 1007
EK R QE ++ Q++E+ +GE+ EK QE+EK R+EE+++++EE+ +RE+
Sbjct: 536 EEKIREQE---------EMMQEQEEKMGEQEEK--MQEQEKMRRQEEKIREQEEK-IREQ 583
Query: 1008 REKRRRQE---WERQ--YRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQ 1062
+EK R QE WE++ R+++E+ QE+E+ + E+ EK QE + Q +EE+ +QEE+
Sbjct: 584 KEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 643
Query: 1063 LLGEERETRRRQELERQYRKEEELQ 1087
E+E R RQ+ E+ +E L+
Sbjct: 644 W---EQEVRLRQQEEKMQEHQEHLE 665
Score = 235 bits (599), Expect = 4e-61
Identities = 167/609 (27%), Positives = 355/609 (58%), Gaps = 61/609 (10%)
Query: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE--ERLEQRLKREEVERL 610
+E+K Q + R + E + ++L ++ Q L Q ++LE R+ + RL
Sbjct: 109 DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEA-RDLISRL 167
Query: 611 EQEER----REQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666
+ EQ L ++++ + ++ E +ER L + ++ LK E+
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIE-ELTKERDALSLELYRNTITDEELK--EKNA 224
Query: 667 RLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ 726
+L+++L+ E E+ E +L +E ++ ER K +P Q QL++EAD ++ S K
Sbjct: 225 KLQEKLQLV-ESEKSEIQLNVKELKRKLERAKLLLP--QQQLQAEADHLGKELQSVSAKL 281
Query: 727 EGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA 786
+ Q E + +++ E W++EE+ +++ +++ + + E+ E+ R++
Sbjct: 282 QAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE-----KIREQEEKIREQ--- 333
Query: 787 RPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERA 846
+R Q E EE+ +R++ + E+EEK RR + EKE + E EE++ +E+
Sbjct: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK-MRRLEEMMWEKEEKIRELEEKMHEQEKI 392
Query: 847 QQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLL 906
++ +E+ ++++E+ R QE+R++Q+ + +EE+ R + +E++R++++ +
Sbjct: 393 REQEEK----RQEEEKIREQEKRQEQEAKMWRQEEKIREQ---------EEKIREQEKKM 439
Query: 907 QEEEEELQREE--REKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDK 964
+EE++ +E RE+ +RQEQE +R+EE+++++EE R+K + E+E+ ++++
Sbjct: 440 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW----RQKEKMHEQEKIRKQEE 495
Query: 965 KLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKD 1024
K+ ++EE++ + E++ R++ EK +R+EE+++++EE++ RE+ EK R QE
Sbjct: 496 KVWRQEEKM--HDQEEKIREQEEKMWRQEEKIREQEEKI-REQEEKIREQE--------- 543
Query: 1025 ELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEE 1084
E+ QE+E+ + E+ EK +QE+E+ R+EE+++++EE+ + E++E R QE E+ + +EE
Sbjct: 544 EMMQEQEEKMGEQEEK--MQEQEKMRRQEEKIREQEEK-IREQKEKIREQE-EKIWEQEE 599
Query: 1085 ELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEE 1144
+++++EE + +E E++ ++ E+ C +EE++Q++EE++ R+E EK QE+ R ++EE
Sbjct: 600 KIREQEEMM--QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE-EKMWEQEV-RLRQQEE 655
Query: 1145 EVQQEEEQL 1153
++Q+ +E L
Sbjct: 656 KMQEHQEHL 664
Score = 227 bits (579), Expect = 8e-59
Identities = 153/502 (30%), Positives = 313/502 (62%), Gaps = 57/502 (11%)
Query: 143 EQERELAEGEEQSEKQERLEQRDRQRRDE---ELWRQRQEWQEREERRAE-EEQLQSCKG 198
E E+ L+ Q +K +R + + RD EL+R +E +E+ A+ +E+LQ +
Sbjct: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
Query: 199 HETEEFPDEEQLRRR----ELL--------ELRRKGRE--------EKQQQRRERQDRVF 238
++E + ++L+R+ +LL E G+E + Q + E +R+
Sbjct: 236 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295
Query: 239 QEEEEKEWRKRETVLRKEEEKLQEEEP---QRQRELQEEEEQLRKLE------RQELRRE 289
Q++EEK WR+ E + ++ EEK+QE+E +++ +++E+EE++R+ E +++RR+
Sbjct: 296 QQQEEKMWRQEEKI-QEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 354
Query: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQ 349
+ ++++++RR +++ ++EE+ RE +E+ EQ++ REQ+E+R+E++ REQE+R+EQ
Sbjct: 355 EEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ 414
Query: 350 QLRREQEEERREQQLRREQEEERREQQLR--REQQLRREQQLRREQQLRREQQ--LRREQ 405
+ + ++EE+ REQEE+ REQ+ + R+++ EQ+ RE++ R+EQ+ R+E+
Sbjct: 415 EAKMWRQEEK-----IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 469
Query: 406 QLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETE 465
++R ++++ R+++ EQ+ R+QEE+ Q+ + +E+++ REQEE+ W + E+ E
Sbjct: 470 KIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKI-REQEEKM-WRQEEKIRE 527
Query: 466 RHEQERRKQQLKRDQEEERRERWLKL-EEEERREQQE---RREQQLRREQEERREQRLKR 521
+ E+ R +++ R+QEE +E+ K+ E+EE+ ++QE R+E+++R ++E+ REQ+ K
Sbjct: 528 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKI 587
Query: 522 QEEEERL---QQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQL 578
+E+EE++ ++++R ++++ +EQEE+ + +EEK EQE + Q + + + +++
Sbjct: 588 REQEEKIWEQEEKIREQEEMMQEQEEK----MWEQEEKMCEQEEKMQEQEEKMRRQEEKM 643
Query: 579 LKREEERRQQRLK-REQEERLE 599
++E RQQ K +E +E LE
Sbjct: 644 WEQEVRLRQQEEKMQEHQEHLE 665
Score = 219 bits (557), Expect = 3e-56
Identities = 173/629 (27%), Positives = 344/629 (54%), Gaps = 90/629 (14%)
Query: 678 EERREQELAEEEQEQARERIKSRIPKWQWQLESEA-DARQSKVYSRPRKQ---------- 726
+E R+ +LAE A+E++ P+ + + A D ++ K+ + +
Sbjct: 53 KETRQSKLAE-----AKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSP 107
Query: 727 EGQRRRQEQEEKRRRRE---------------SELQWQEEERAHRQQQEEEQRRDF---- 767
E +++ Q ++ RRE +ELQ H +Q E + RD
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 768 --TWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQRE-------QRFLPEEEEKE 818
+W++ E + Q LSA +++ +R + E ++R+ + + +EE KE
Sbjct: 168 HDSWKFAGELE-----QALSAVATQKKKADRYIE-ELTKERDALSLELYRNTITDEELKE 221
Query: 819 -----QRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQK 873
Q + Q E EK L +E ++ ERA+ L ++ LQ + + + Q K
Sbjct: 222 KNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ-LQAEADHLGKELQSVSAK 280
Query: 874 WRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREE 933
+ Q+EE R +E++ ++++ +QE EE++Q +E + R EQE + RE+
Sbjct: 281 LQAQVEENELWNR----LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR---EQEEKIREQ 333
Query: 934 EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQER---EKKY 990
E+ + +E+++ E+ EK RRQE E + K++K+++ EE + +E + R +E+ ++K
Sbjct: 334 EEKMRRQEEMMWEKEEKMRRQE-EMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKI 392
Query: 991 REEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER--ER 1048
RE+EE +QEEE++ E+EKR+ QE + +R++++++++EE++ +E++ R +E+ E+
Sbjct: 393 REQEEKRQEEEKI--REQEKRQEQE-AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ 449
Query: 1049 QYREEEELQQEEEQLLGEERETRRRQELERQYRK---EEELQQEEEQLLREEP-----EK 1100
+ EEE +QE+E++ +E + R ++E+ RQ K +E+++++EE++ R+E E+
Sbjct: 450 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEE 509
Query: 1101 RRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREE-----EEVQQEEEQLLR 1155
+ R++ E+ R+EE+++++EE++ RE+ EK R QE Q +EE EE QE+E++ R
Sbjct: 510 KIREQEEKMWRQEEKIREQEEKI-REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRR 568
Query: 1156 EEPEKRRRQELERQY----REEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRK 1211
+E + R ++E R+ RE+EE E+E+ +RE++E +++ E+ + +EE++ Q+ K
Sbjct: 569 QEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 628
Query: 1212 QRYRDEDQRSDLKWQWEPEKENAVRDNKV 1240
+ ++E R + WE E ++ K+
Sbjct: 629 MQEQEEKMRRQEEKMWEQEVRLRQQEEKM 657
Score = 218 bits (555), Expect = 5e-56
Identities = 157/579 (27%), Positives = 324/579 (55%), Gaps = 53/579 (9%)
Query: 977 EPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE 1036
E E++ + ++ R E E Q ++L ++ + + + Q+ K +L+ E L+
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVK-QLEGEARDLISR 166
Query: 1037 EREKRRLQ------------ERERQYREEEELQQEEEQLLGE-ERETRRRQELERQYRKE 1083
+ + ++++ R EEL +E + L E R T +EL+ + K
Sbjct: 167 LHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKL 226
Query: 1084 EE----LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ 1139
+E ++ E+ ++ E +R+ ER + +++LQ E + L +E + + L+ Q
Sbjct: 227 QEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK--LQAQ 284
Query: 1140 YREEEEV----QQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
E E QQ+EE++ R+E + QE E + +E+EE +E+E+ +RE++EK R++
Sbjct: 285 VEENELWNRLNQQQEEKMWRQE---EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 341
Query: 1196 ERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYC--KGRENEQFRQL 1253
E + +EE+++RQ+ ++E R + WE E++ + K++ K RE E+ RQ
Sbjct: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ- 400
Query: 1254 EDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRK 1313
E+ ++R+++ +Q+ + + Q+E+ REQE + +Q + + +EE++ +E+ R + K
Sbjct: 401 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK---IREEEK 457
Query: 1314 SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQG 1373
QE++++ R+E + + + + +K + EQ ++E+ + RQE +EE++R QE+
Sbjct: 458 RQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEE- 516
Query: 1374 RKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQER----D 1429
K +E+++R E+E K ++E+++R QE ++ Q+++ K E+E+++ QE+ +
Sbjct: 517 -KMWRQEEKIR--EQEEKIREQEEKIREQE---EMMQEQEEKMGEQEEKMQEQEKMRRQE 570
Query: 1430 RKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQER----DR 1485
K RE+E+++R E++ K E+E+++ E+ K RE+E+++QE+EE+ ++E+ +
Sbjct: 571 EKIREQEEKIR--EQKEKIREQEEKI-WEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 627
Query: 1486 KFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524
K E+E+++RRQE K EQE+R ++ E K E ++ L
Sbjct: 628 KMQEQEEKMRRQE--EKMWEQEVRLRQQEEKMQEHQEHL 664
Score = 216 bits (550), Expect = 2e-55
Identities = 172/583 (29%), Positives = 331/583 (56%), Gaps = 47/583 (8%)
Query: 115 QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ-SEKQERLEQRDRQRRDEEL 173
Q+ + E R+LE + R Q+ E ++A Q + KQ E RD R +
Sbjct: 111 QKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDS 170
Query: 174 WRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRER 233
W+ E ++ A +++ EE E EL E K++ + +
Sbjct: 171 WKFAGELEQALSAVATQKKKAD---RYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
Query: 234 QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ-- 291
+ E E+ E + L+++ E+ + PQ+Q LQ E + L K E Q + + Q
Sbjct: 228 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ--LQAEADHLGK-ELQSVSAKLQAQ 284
Query: 292 -EEEQQQQRLRREQQLRRKQEEERREQQEERREQQER--REQQEERREQQLRREQEERRE 348
EE + RL ++Q+ + ++EE+ ++ EE+ ++QE REQ+E+ REQ+ E+ R+E
Sbjct: 285 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE---EKMRRQE 341
Query: 349 QQLRREQEEERREQQLRREQEEERR---EQQLRREQQLRR-EQQLRREQQLRREQQLRRE 404
+ + ++E+ RR++++ E+EE+ R E +E+++R E+++ ++++R +++ R+E
Sbjct: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 401
Query: 405 QQLRREQQLRREQQLR--REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREE 462
++ REQ+ R+EQ+ + R+++ REQEE+ EQ+ + R+E+++ EQE+ R EE
Sbjct: 402 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI-HEQEKIR-----EE 455
Query: 463 ETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQ 522
E + ++E +Q+ ++ E+ E W + E+ +E+ ++E+++ R++E+ +Q K +
Sbjct: 456 EKRQEQEEMWRQE---EKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIR 512
Query: 523 EEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKRE 582
E+EE++ R E+++R ++E+ REQ EEK EQE Q + + E+ +++ ++E
Sbjct: 513 EQEEKM---WRQEEKIREQEEKIREQ-----EEKIREQEEMMQEQEEKMGEQEEKMQEQE 564
Query: 583 EERRQQRLKREQEERL-EQRLK-REEVERL-EQEER-REQRLKREEPEEERRQQLLKSEE 638
+ RRQ+ REQEE++ EQ+ K RE+ E++ EQEE+ REQ +E EE+ +Q K E
Sbjct: 565 KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCE 624
Query: 639 QEERRQQQ---LRREQQERREQRLKREEEEERLEQRLKREHEE 678
QEE+ Q+Q +RR++++ EQ ++ ++EE++++ +EH E
Sbjct: 625 QEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH--QEHLE 665
Score = 214 bits (545), Expect = 7e-55
Identities = 184/631 (29%), Positives = 340/631 (53%), Gaps = 100/631 (15%)
Query: 908 EEEEELQREEREKRRRQEQERQY--------REEEQLQQEEEQLLREEREKRRRQERERQ 959
E+E++ + +E RR+ + + + + E Q+ Q ++ E R R
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQ 1019
+ K + E+ L +K++ R EEL +E + L E R + +
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKAD------RYIEELTKERDAL---SLELYRNTITDEE 218
Query: 1020 YRKKDELQQEEEQLLREER--------EKRRLQERERQYREEEELQQEEEQLLGEERET- 1070
++K+ QE+ QL+ E+ E +R ER + +++LQ E + L G+E ++
Sbjct: 219 LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHL-GKELQSV 277
Query: 1071 --RRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREER 1128
+ + ++E QQ+EE++ R+E + QE E + +E+EE +E+E+ +RE+
Sbjct: 278 SAKLQAQVEENELWNRLNQQQEEKMWRQE---EKIQEWEEKIQEQEEKIREQEEKIREQE 334
Query: 1129 EKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQEL----ERQYREEEELQQEEEQLL 1184
EK RRQE E + +EE+++++EE + +E + RR +E+ E + RE EE E+E+ +
Sbjct: 335 EKMRRQE-EMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK-I 392
Query: 1185 REEQEKRRQE---RERQYREEEE--LQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNK 1239
RE++EKR++E RE++ R+E+E + RQ+ K R ++E R K W E+
Sbjct: 393 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE-------- 444
Query: 1240 VYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQL 1299
K E E+ R+ E RQ Q++ + Q+E+ REQE W+Q+++ E+E++
Sbjct: 445 ---KIHEQEKIREEE-----KRQEQEE----MWRQEEKIREQE-EIWRQKEK-MHEQEKI 490
Query: 1300 EREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERD 1359
++E+K ++ ++ +E+++ E+EEK RQE K RE+E+ ++E+EE
Sbjct: 491 RKQEEKVWRQEEKMHDQEEKI--REQEEKMWRQE--EKIREQEEKIREQEE--------- 537
Query: 1360 RKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREE 1419
K RE+E QEQ K E+E++++ QE+ R+ Q+ + +E+E+++R+ ++ K RE+
Sbjct: 538 -KIREQEEMMQEQEEKMGEQEEKMQEQEKMRR-----QEEKIREQEEKIREQKE-KIREQ 590
Query: 1420 EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLH 1479
E+++ QE K RE+E+ + QE+E K E+E+ K E+E+ +QE+EE ++
Sbjct: 591 EEKIWEQE--EKIREQEEMM--QEQEEKMWEQEE--------KMCEQEEKMQEQEE-KMR 637
Query: 1480 RQERDRKFLEEEQQLRRQERDRKFREQELRS 1510
RQE K E+E +LR+QE + ++ L +
Sbjct: 638 RQE--EKMWEQEVRLRQQEEKMQEHQEHLEA 666
Score = 213 bits (541), Expect = 2e-54
Identities = 181/628 (28%), Positives = 338/628 (53%), Gaps = 102/628 (16%)
Query: 1292 HFPEEEQLEREEQKEAKRRDRKSQEE-----------------------KQLLREEREEK 1328
H PE+EQ + +EA RR+ ++Q KQL E R+
Sbjct: 105 HSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLI 164
Query: 1329 RRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQER 1388
R ++ + E EQ L Q +++ DR EEL + + +E
Sbjct: 165 SRLHDSWKFAGELEQALSAVATQ---KKKADRYI--EELTKERDALSLELYRNTITDEEL 219
Query: 1389 ERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQE--RER 1446
+ K K +++L+ E E+ E QL+ +E RK + + +Q+ E
Sbjct: 220 KEKNAKLQEKLQLVESEKS------------EIQLNVKELKRKLERAKLLLPQQQLQAEA 267
Query: 1447 KFLEEEQQLRQERHRKFREEEQL---LQEREEQQLHRQER-----DRKFLEEEQQLRRQE 1498
L +E Q + + EE +L L +++E+++ RQE + K E+E+++R QE
Sbjct: 268 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 327
Query: 1499 RDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFR 1558
K REQE + + E E+E+++ RQ+ ++E+++RR E ++++ R+
Sbjct: 328 E--KIREQEEKMRRQEEMMWEKEEKMRRQEEM--MWEKEEKMRRLEEMMWEKEEKIRELE 383
Query: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD 1618
E+ +++ EQ+ RQE ++ + EQ+ +RQEQE K E+++R QE
Sbjct: 384 EKMHEQEKIREQEEKRQEEEK---IREQE-KRQEQEAKMWRQEEKIREQE---------- 429
Query: 1619 RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQE 1678
K RE E+ + R+E+++H QE+ R EEE +RQE+E+ R ++ K RE+E++ ++
Sbjct: 430 EKIREQEKKMW-RQEEKIHEQEKIR---EEE---KRQEQEEMWR--QEEKIREQEEIWRQ 480
Query: 1679 GEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE 1738
E+ + QE K R++E+++ RQE K +E+++R QE E+ +R+EE++R++ +E
Sbjct: 481 KEK--MHEQE---KIRKQEEKVWRQEE--KMHDQEEKIREQE-EKMWRQEEKIREQ--EE 530
Query: 1739 QLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFR 1798
++R QE KI E+E++ E+EE+ E++ K +E+E++R R+E+++R QE K R
Sbjct: 531 KIREQEE--KIREQEEMMQEQEEKM---GEQEEKMQEQEKMR--RQEEKIREQE--EKIR 581
Query: 1799 EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQ-EKS 1857
E+++ +E+EE + +++ K R +EE +Q EQE+++ ++ ++ EE+ Q EK
Sbjct: 582 EQKEKIREQEE---KIWEQEEKIREQEEMMQ--EQEEKMWEQEEKMCEQEEKMQEQEEKM 636
Query: 1858 RREEQELWQEEEQKRRQERERKLREEHI 1885
RR+E+++W++E + R+QE + + +EH+
Sbjct: 637 RRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
Score = 208 bits (530), Expect = 4e-53
Identities = 158/547 (28%), Positives = 311/547 (56%), Gaps = 59/547 (10%)
Query: 37 LEREFGAVLRRPHDP-KTVDLILELLDLDSNGRVDFNEFLLFIFKVAQACYYALGQATGL 95
LE E ++ R HD K + + L + + + ++ + K A L + T
Sbjct: 156 LEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTIT 215
Query: 96 DEE---KRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEE----PGQRRRQKRQEQEREL 148
DEE K A+ K L++ + E Q + R+LE P Q+ + + +EL
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEI-QLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 274
Query: 149 ----AEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
A+ + Q E+ E L R Q+++E++WRQ ++ QE EE+ E+E+ + E +
Sbjct: 275 QSVSAKLQAQVEENE-LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE--KIREQEEKIR 331
Query: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE 264
EE++RR+E + ++ + +Q++ ++ + EE W K E + EE+ ++E+
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK 391
Query: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
+ Q E ++EEE++R E+++ ++Q+ ++ R+++ R+QEE+ REQ+++ Q
Sbjct: 392 IREQEEKRQEEEKIR---------EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ 442
Query: 325 QERREQQEERREQQLRREQEE--RREQQLRREQEEERREQQLRREQEEERREQQLRREQQ 382
+E+ +QE+ RE++ R+EQEE R+E+++ REQEE R+++ EQE+ R+++ E+
Sbjct: 443 EEKIHEQEKIREEEKRQEQEEMWRQEEKI-REQEEIWRQKEKMHEQEKIRKQE----EKV 497
Query: 383 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQER 442
R+E+++ +++ REQ+ E+ R+E+++R +++ REQEE+ EQ
Sbjct: 498 WRQEEKMHDQEEKIREQE---------EKMWRQEEKIREQEEKIREQEEKIREQ------ 542
Query: 443 REQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERR--EQQ 500
+ + +EQEE+ ++EE+ + E+ RR+++ R+QEE+ RE+ K+ E+E + EQ+
Sbjct: 543 --EEMMQEQEEKMG--EQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE 598
Query: 501 E--RREQQLRREQEERR-EQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKR 557
E R ++++ +EQEE+ EQ K E+EE++Q++ E+++RR++E+ EQ ++ +++
Sbjct: 599 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ---EEKMRRQEEKMWEQEVRLRQQEE 655
Query: 558 LEQERRE 564
QE +E
Sbjct: 656 KMQEHQE 662
Score = 208 bits (530), Expect = 4e-53
Identities = 157/481 (32%), Positives = 297/481 (61%), Gaps = 57/481 (11%)
Query: 257 EEKLQEEEPQRQRELQ--EEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314
+E+L+E+ + Q +LQ E E+ +L +EL+R+ + + + L +QQL+ + +
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLE----RAKLLLPQQQLQAEADHLG 271
Query: 315 REQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERRE 374
+E Q + Q + E+ E +L ++QEE+ +Q + QE E + Q EQEE+ RE
Sbjct: 272 KELQSVSAKLQAQVEENE--LWNRLNQQQEEKMWRQEEKIQEWEEKIQ----EQEEKIRE 325
Query: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL--RREQQLRREQQLRREQEE- 431
Q+ + +Q E+++RR++++ E +E+++RR++++ +E+++RR +++ E+EE
Sbjct: 326 QEEKIREQ---EEKMRRQEEMMWE----KEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEK 378
Query: 432 --ERHEQKHEQER-REQRLKREQEERRDWLKREEETERHEQER---RKQQLKRDQEEERR 485
E E+ HEQE+ REQ KR++EE K E+ +R EQE R+++ R+QEE+ R
Sbjct: 379 IRELEEKMHEQEKIREQEEKRQEEE-----KIREQEKRQEQEAKMWRQEEKIREQEEKIR 433
Query: 486 ERWLKL--EEEERREQQERREQQLRREQEE--RREQRLKRQEEEERLQQRLRSEQQLRRE 541
E+ K+ +EE+ EQ++ RE++ R+EQEE R+E++++ QEE R ++++ ++++R++
Sbjct: 434 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
Query: 542 QEE--RREQLLKREEEKRLEQE----RREQRLKREQEERRDQLLKREEERRQQRLKREQE 595
+E+ R+E+ + +EEK EQE R+E++++ ++E+ R+Q E+ R Q+ + +EQE
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQ---EEKIREQEEMMQEQE 550
Query: 596 ERL---EQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE--RRQQQLRRE 650
E++ E++++ +E R ++E+ REQ K E +E+ R+Q K EQEE R Q+++ +E
Sbjct: 551 EKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQE 610
Query: 651 QQERR-EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLE 709
Q+E+ EQ K E+EE+++ E EE+ R QE EQE + + ++ + Q LE
Sbjct: 611 QEEKMWEQEEKMCEQEEKMQ-----EQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
Query: 710 S 710
+
Sbjct: 666 A 666
Score = 206 bits (523), Expect = 2e-52
Identities = 157/560 (28%), Positives = 308/560 (55%), Gaps = 61/560 (10%)
Query: 1387 ERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVR----RQ 1442
E E+K + Q+ +E E Q+ R ++ E Q++ ++ E + R R
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 1443 ERERKFLEEEQQ----LRQERHRKFREEEQLLQERE--EQQLHR--------QERDRKFL 1488
KF E +Q + ++ + R E+L +ER+ +L+R +E++ K
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
Query: 1489 EEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQ 1548
E+ Q + ++ + + +EL+ + K L +QQL Q +E Q + + + Q
Sbjct: 228 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQL--QAEADHLGKELQSVSAKLQAQV 285
Query: 1549 RRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQE 1608
+ + ++++ + R+E+++ QE + K + +E+K+R EQE K E E+++RRQE
Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKI--QEWEEKIQEQEEKIR--EQEEKIREQEEKMRRQE 341
Query: 1609 GQQQLRQERDRKFREDEQLLQEREEQQLHRQE----RDRKFLEEEPQLRRQE--REQQLR 1662
++ E++ K R E+++ E+EE+ +E ++ K E E ++ QE REQ+ +
Sbjct: 342 ---EMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEK 398
Query: 1663 HDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQE----RERKFLQEEQQLR- 1717
+ K RE+E+ +EQ+ + ++ K RE+E+++R QE R+ + + E++++R
Sbjct: 399 RQEEEKIREQEKR----QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 454
Query: 1718 ---RQELERKFREEEQLRQETE----QEQLRRQERYRKILEEEQLRPEREEQQLRRQERD 1770
RQE E +R+EE++R++ E +E++ QE+ RK +EE++ R+E+++ QE
Sbjct: 455 EEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRK--QEEKVW--RQEEKMHDQEEK 510
Query: 1771 RKFREEEQLRQERE--EQQLRSQESDRKFREEEQLRQEREE---QQLRPQQRDGKYRWEE 1825
+ +EE+ RQE + EQ+ + +E + K RE+E++ QE+EE +Q Q K R +E
Sbjct: 511 IREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQE 570
Query: 1826 EQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHI 1885
E+++ EQE+++R+++++ EE+ QE+ RE++E+ QE+E+K E+E K+ E+
Sbjct: 571 EKIR--EQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEK-MWEQEEKMCEQEE 627
Query: 1886 RRQQKEEQRHRQVGEIKSQE 1905
+ Q++EE+ RQ ++ QE
Sbjct: 628 KMQEQEEKMRRQEEKMWEQE 647
Score = 205 bits (522), Expect = 3e-52
Identities = 162/531 (30%), Positives = 305/531 (57%), Gaps = 81/531 (15%)
Query: 273 EEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
E E+ L + Q+ + +R EE ++R +L R + +++ + Q++ + +
Sbjct: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
Query: 333 ERREQQLRREQEERR---------EQQLRREQEEERREQQ-----LRREQEEER---REQ 375
E+ E QL ++ +R+ +QQL+ E + +E Q L+ + EE R
Sbjct: 236 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295
Query: 376 QLRREQQLRREQQLRR-EQQLRREQQLRREQQLR---REQQLRREQQLRREQQLRREQEE 431
Q + E+ R+E++++ E++++ +++ REQ+ + +E+++RR++++ E++ + ++E
Sbjct: 296 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 355
Query: 432 ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKL 491
E +K E+ RR + + E+EE+ RE E + HEQE+ ++Q ++ QEEE K+
Sbjct: 356 EMMWEKEEKMRRLEEMMWEKEEKI----RELEEKMHEQEKIREQEEKRQEEE------KI 405
Query: 492 EEEERREQQE----RREQQLRREQEERREQRLK--RQEEEERLQQRLRSEQQLRREQEE- 544
E+E+R++QE R+E+++R ++E+ REQ K RQEE+ Q+++R E++ R+EQEE
Sbjct: 406 REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK-RQEQEEM 464
Query: 545 --RREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK-REQEERL--- 598
+ E++ ++EE R +++ EQ R+QEE+ + ++EE+ Q K REQEE++
Sbjct: 465 WRQEEKIREQEEIWRQKEKMHEQEKIRKQEEK---VWRQEEKMHDQEEKIREQEEKMWRQ 521
Query: 599 EQRLKREEVERLEQEER-REQRLKREEPEEERRQQLLKSEEQEE-RRQQQLRREQQER-R 655
E++++ +E + EQEE+ REQ +E EE+ +Q K +EQE+ RRQ++ REQ+E+ R
Sbjct: 522 EEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIR 581
Query: 656 EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADAR 715
EQ+ K E+EE++ E EE+ REQE +EQE+ W+ E + +
Sbjct: 582 EQKEKIREQEEKI-----WEQEEKIREQEEMMQEQEEK-----------MWEQEEKMCEQ 625
Query: 716 QSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRD 766
+ K+ QEQEEK RR+E E W++E R +Q+++ ++ ++
Sbjct: 626 EEKM-------------QEQEEKMRRQE-EKMWEQEVRLRQQEEKMQEHQE 662
Score = 201 bits (512), Expect = 4e-51
Identities = 181/612 (29%), Positives = 341/612 (55%), Gaps = 89/612 (14%)
Query: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208
E+EQ + ++ R+ELE Q L ++ +L + ++ + + + R
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 1209 KRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGREN---EQFRQ-LEDSQLRDRQS- 1263
++ E +++ +K+ A R + K R+ E +R + D +L+++ +
Sbjct: 168 HDSWKFAGELEQA--LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 225
Query: 1264 -QQDLQHLLGEQQERDRE-QERRRWQQRDRHFPEEEQLEREEQ---KEAKRRDRKSQ--- 1315
Q+ LQ + E+ E +E +R +R + ++QL+ E KE + K Q
Sbjct: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
Query: 1316 EEKQL---LREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQ 1372
EE +L L +++EEK RQE K +E E+ +QE+EE+ +R QE + +EE++R QE+
Sbjct: 286 EENELWNRLNQQQEEKMWRQE--EKIQEWEEKIQEQEEK-IREQEEKIREQEEKMRRQEE 342
Query: 1373 GRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKF 1432
E+E+++RRQE E + KEE+ R +E + +++ K RE E+++ QE+ R+
Sbjct: 343 --MMWEKEEKMRRQE-EMMWEKEEKMRRLEE----MMWEKEEKIRELEEKMHEQEKIREQ 395
Query: 1433 ---REEEQQVR----RQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDR 1485
R+EE+++R RQE+E K +E+++R E+ K RE+E+ + R+E+++H QE+ R
Sbjct: 396 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIR-EQEEKIREQEKKMW-RQEEKIHEQEKIR 453
Query: 1486 KFLEEEQQLRRQERDRKFREQE-LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQE 1544
EEE +RQE++ +R++E +R QE + +++++H Q++ RK +E+++ RQE
Sbjct: 454 ---EEE---KRQEQEEMWRQEEKIREQE---EIWRQKEKMHEQEKIRK---QEEKVWRQE 501
Query: 1545 RGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQL 1604
++ D++ K RE+E+ K +E+K+R EQE K E E+++
Sbjct: 502 ---EKMHDQEEKIREQEE-----------------KMWRQEEKIR--EQEEKIREQEEKI 539
Query: 1605 RRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQE---REQQL 1661
R QE ++ QE++ K E E+ +QE+E ++ RQE K E+E ++R Q+ REQ+
Sbjct: 540 REQE---EMMQEQEEKMGEQEEKMQEQE--KMRRQE--EKIREQEEKIREQKEKIREQEE 592
Query: 1662 R-HDRDRKFREEEQLLQEGEEQQLRRQER----DRKFREEEQQLRRQERERKFLQEEQQL 1716
+ +++ K RE+E+++QE EE+ ++E+ + K +E+E+++RRQ E K ++E +L
Sbjct: 593 KIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ--EEKMWEQEVRL 650
Query: 1717 RRQELERKFREE 1728
R+QE + + +E
Sbjct: 651 RQQEEKMQEHQE 662
Score = 201 bits (512), Expect = 4e-51
Identities = 167/613 (27%), Positives = 326/613 (53%), Gaps = 80/613 (13%)
Query: 1178 QEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRD 1237
++E++ + QE R+E E Q L QK + + L + K+
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMA-------LYYSQHAVKQ----- 155
Query: 1238 NKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEE 1297
+G + +L DS + +Q L + ++++ DR E ++RD E
Sbjct: 156 ----LEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELT-KERDA-LSLEL 209
Query: 1298 QLEREEQKEAKRRDRKSQEEKQLLREER-------EEKRRRQETDRKFREEEQLLQEREE 1350
+E K ++ K QE+ QL+ E+ +E +R+ E + ++QL E +
Sbjct: 210 YRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADH 269
Query: 1351 QPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQ 1410
Q K + + ++ R ++E+++ RQE + +E + + QE+E+++R+
Sbjct: 270 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKI----QEWEEKIQEQEEKIRE 325
Query: 1411 DRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQL- 1469
++ K RE+E+++ RQE E+E+++RRQE E+E+++R+ + +EE++
Sbjct: 326 -QEEKIREQEEKMRRQEE--MMWEKEEKMRRQEE--MMWEKEEKMRRLEEMMWEKEEKIR 380
Query: 1470 -LQEREEQQLHRQERDRKFLEEE---QQLRRQERDRKFREQELRSQEPERKFLEEEQQLH 1525
L+E+ +Q +E++ K EEE +Q +RQE++ K QE + +E E K E+E+++
Sbjct: 381 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 440
Query: 1526 RQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE-QQLSRQERDRKFRLE 1584
RQ+ + + E++++R +E+ RQ+++ +R+EE++R++ E +Q + K R +
Sbjct: 441 RQEEK---IHEQEKIREEEK----RQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
Query: 1585 EQKVRRQE-----QERKFMEDEQQLRRQEG----QQQLRQERDRKFREDEQLLQEREEQQ 1635
E+KV RQE QE K E E+++ RQE Q++ +E++ K RE E+++QE+EE+
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553
Query: 1636 LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFRE 1695
++E+ ++E+ ++RRQE K RE+E+ ++E +E + +E++ K E
Sbjct: 554 GEQEEK----MQEQEKMRRQEE----------KIREQEEKIREQKE---KIREQEEKIWE 596
Query: 1696 EEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQL 1755
+E+++R QE + +EQ+ + E E K E+E+ QE ++E++RRQE K+ E+E
Sbjct: 597 QEEKIREQEE----MMQEQEEKMWEQEEKMCEQEEKMQE-QEEKMRRQE--EKMWEQEVR 649
Query: 1756 RPEREEQQLRRQE 1768
++EE+ QE
Sbjct: 650 LRQQEEKMQEHQE 662
Score = 196 bits (498), Expect = 2e-49
Identities = 150/588 (25%), Positives = 328/588 (55%), Gaps = 55/588 (9%)
Query: 264 EPQRQRELQEEEEQLRKLERQ--ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321
E +++ Q +E R+LE Q +R ++ + Q L Q ++ E E R+
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 322 REQQERREQQEERREQ-QLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRRE 380
+ + + E+ ++++ +R ++L +E++ E +EE +E+ + +
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
Query: 381 QQLRREQQLRREQQLRREQ---QLRREQQLRREQQLRRE-----QQLRREQQLRREQEEE 432
++L+ + + E QL ++ +L R + L +QQL+ E ++L+ + Q EE
Sbjct: 228 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 287
Query: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLK-RDQEEE-RRERWLK 490
+++E+++ R++E+ ++W EE+ + E++ R+Q+ K R+QEE+ RR+ +
Sbjct: 288 NELWNRLNQQQEEKMWRQEEKIQEW---EEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 344
Query: 491 LEEEERREQQER----REQQLRREQEE--RREQRLKRQEEEERLQQRLRSEQQLRREQEE 544
E+EE+ +QE +E+++RR +E +E++++ EE+ Q+++R +++ R+E+E+
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 404
Query: 545 RREQLLKREEEKRLEQERREQRLKREQEERRDQ---LLKREEERRQQRLKREQEERLEQR 601
REQ ++E+E ++ R+E++++ ++E+ R+Q + ++EE+ +Q RE+E+R EQ
Sbjct: 405 IREQEKRQEQEAKM--WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQ- 461
Query: 602 LKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKR 661
EE+ R E++ R ++ + R++ + ++++ K EE+ R+++++ ++++ REQ K
Sbjct: 462 ---EEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKM 518
Query: 662 EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYS 721
+EE++ RE EE+ REQE EQE+ + + ++ + + +++ + R+ +
Sbjct: 519 WRQEEKI-----REQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQE--E 571
Query: 722 RPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQ---QEEEQRRDFTWQWQAEEKSE 778
+ R+QE + R EQ+EK R +E ++ W++EE+ Q+ QE+E++ W+ EEK
Sbjct: 572 KIREQEEKIR--EQKEKIREQEEKI-WEQEEKIREQEEMMQEQEEK-----MWEQEEKMC 623
Query: 779 RGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRE 826
++ ++EQ E+ R EE+ ++ L ++EEK Q ++ E
Sbjct: 624 EQEEK------MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
Score = 193 bits (490), Expect = 2e-48
Identities = 153/569 (26%), Positives = 307/569 (53%), Gaps = 85/569 (14%)
Query: 1119 EEEQLLREEREKRRRQELERQYR-------EEEEVQQE--EEQLLREEPEKRRRQELERQ 1169
E+EQ + ++ R+ELE Q ++ E+Q Q ++ E R + R
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 1170 YREEEELQQEEEQLLREEQEKRRQER--ERQYREEEELQRQKRKQRYRDED-QRSDLKWQ 1226
+ + + E+ L +K++ +R E +E + L + + DE+ + + K Q
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
Query: 1227 WEPEKENAVRDNKVYCKGRENEQFRQLEDSQLR--DRQSQQDLQHLLGEQQE-------- 1276
EK V K + E R+LE ++L +Q Q + HL E Q
Sbjct: 228 ---EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284
Query: 1277 ---------RDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREE--- 1324
+++QE + W+Q ++ EE+++ +E+K ++ ++ ++E+++ R+E
Sbjct: 285 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 344
Query: 1325 --REEKRRRQET-----DRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFL 1377
+EEK RRQE + K R E+++ E+EE+ R+ ++ +E++R QE+ R
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKI--RELEEKMHEQEKIREQEEKR--- 399
Query: 1378 EEEQRLR----RQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEE----QQLSRQERD 1429
+EE+++R RQE+E K ++E+++R E+E+++R+ + +R+EE Q+ R+E
Sbjct: 400 QEEEKIREQEKRQEQEAKMWRQEEKIR--EQEEKIREQEKKMWRQEEKIHEQEKIREEEK 457
Query: 1430 RKFREE----EQQVRRQE---RERKFLEEEQQLRQERHRKFREEEQLLQERE-----EQQ 1477
R+ +EE E+++R QE R+++ + E++++R++ + +R+EE++ + E E++
Sbjct: 458 RQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEK 517
Query: 1478 LHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR----KF 1533
+ RQE K E+E+++R QE K REQE QE E K E+E+++ Q++ R K
Sbjct: 518 MWRQEE--KIREQEEKIREQEE--KIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKI 573
Query: 1534 LQEEQQLRRQERGQQRRQDR----DRKFREEEQLRQEREEQQLSRQER--DRKFRLEEQK 1587
++E+++R Q+ + ++++ + K RE+E++ QE+EE+ ++E+ +++ +++EQ+
Sbjct: 574 REQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 633
Query: 1588 VRRQEQERKFMEDEQQLRRQEGQQQLRQE 1616
+ + QE K E E +LR+QE + Q QE
Sbjct: 634 EKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 191 bits (486), Expect = 5e-48
Identities = 154/583 (26%), Positives = 311/583 (53%), Gaps = 100/583 (17%)
Query: 420 RREQQLRREQEEERHE------QKHEQERR----EQRLKREQEERRDWLKREEE------ 463
+ ++ LRRE E + H QK E + + +K+ + E RD + R +
Sbjct: 116 QHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAG 175
Query: 464 ----------TERHEQERRKQQLKRDQE-------------EERRERWLKLEEEERREQQ 500
T++ + +R ++L ++++ EE +E+ KL+E+ + +
Sbjct: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
Query: 501 ERREQQLRREQEERREQRLKRQEEEERLQ----------QRLRSEQQLRREQEERREQLL 550
E+ E QL ++ +R+ +R K +++LQ Q + ++ Q + E+ E +L
Sbjct: 236 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295
Query: 551 KREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK-REQEERL---EQRLKREE 606
+++EEK QE + Q + + +E+ +++ ++EE+ R+Q K R QEE + E++++R+E
Sbjct: 296 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 355
Query: 607 VERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666
E+EE+ + + +EE+ ++L +E+ +Q+ REQ+E+R++ K E+E+
Sbjct: 356 EMMWEKEEKMRRLEEMMWEKEEKIREL-----EEKMHEQEKIREQEEKRQEEEKIREQEK 410
Query: 667 RLEQRLKREHEEER-REQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVY---SR 722
R EQ K +EE+ REQE EQE+ R + +I + + E E Q +++ +
Sbjct: 411 RQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK 470
Query: 723 PRKQEGQRRRQEQ--EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERG 780
R+QE R++E+ E+++ R++ E W++EE+ H QEE+ R W+ EEK
Sbjct: 471 IREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMH--DQEEKIREQEEKMWRQEEKIREQ 528
Query: 781 RQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQL 840
++ +REQ E+ EE Q ++ + E+EEK Q + + R +E++++ E+EE++
Sbjct: 529 EEK------IREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIR--EQEEKI 580
Query: 841 QRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR 900
RE+ ++++E+E+ + E +E+ R QE+ ++ +E++
Sbjct: 581 --REQKEKIREQEEKIWEQEEKIREQEEMMQEQ----------------------EEKMW 616
Query: 901 KEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQL 943
++++ + E+EE++Q E+ EK RRQE E+ + +E +L+Q+EE++
Sbjct: 617 EQEEKMCEQEEKMQ-EQEEKMRRQE-EKMWEQEVRLRQQEEKM 657
Score = 191 bits (485), Expect = 6e-48
Identities = 152/596 (25%), Positives = 312/596 (52%), Gaps = 52/596 (8%)
Query: 316 EQQEERREQQERREQQEERREQQLRREQEERREQQLRR-------EQEEERREQQLRREQ 368
++Q+ + QE ++ E + +R ++ E Q+ +Q E + R
Sbjct: 109 DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLH 168
Query: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428
+ + +L + Q+ + ++ + + R L + +++L+ + +E
Sbjct: 169 DSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQE 228
Query: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREE---ETERHEQERRKQQLKRDQEEERR 485
+ + +K E + + LKR+ E + L +++ E + +E + K + E
Sbjct: 229 KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN 288
Query: 486 ERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEE- 544
E W +L +++ E+ R+E++++ +E+ +EQ K +E+EE+++++ E+++RR++E
Sbjct: 289 ELWNRLNQQQE-EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ---EEKMRRQEEMM 344
Query: 545 -RREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK 603
+E+ ++R+EE E+E + +RL+ E+ +++ + EE+ +Q REQEE K
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEE------K 398
Query: 604 REEVERL-EQEERREQRLKREEPEEERRQQLLKSEEQEER--RQQQLRREQQERREQRLK 660
R+E E++ EQE+R+EQ K EE+ R+Q K EQE++ RQ++ EQ++ RE+ K
Sbjct: 399 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE-K 457
Query: 661 REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVY 720
R+E+EE Q EE+ REQE ++E+ E+ K R ++ KV+
Sbjct: 458 RQEQEEMWRQ------EEKIREQEEIWRQKEKMHEQEKIR-------------KQEEKVW 498
Query: 721 SRPRKQEGQRRR-QEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSER 779
+ K Q + +EQEEK R+E +++ QEE+ ++QEE+ R + EEK
Sbjct: 499 RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKI---REQEEKIREQEEMMQEQEEKMGE 555
Query: 780 GRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQ 839
+++ + +R Q E+ +R +E + REQ+ E+E++ ++ + RE+E E+EE+
Sbjct: 556 QEEKMQEQEKMRRQEEK-IREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEK 614
Query: 840 LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPAL 895
+ +E +++ E+E+ +QE +E+ R QE++ ++ ++E K + H + + A+
Sbjct: 615 MWEQE--EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
Score = 167 bits (423), Expect = 9e-41
Identities = 109/337 (32%), Positives = 209/337 (62%), Gaps = 40/337 (11%)
Query: 113 RRQEEDQRRFEPRDRQLEE-----EPGQRRRQKRQEQERELAEGEEQSEKQERL-EQRDR 166
RRQEE E + R+LEE E R +++ ++ ++ E EE+ +++E++ EQ R
Sbjct: 352 RRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 411
Query: 167 QRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEK 226
Q ++ ++WRQ ++ +E+EE+ E+E+ + R+ E + + K REE+
Sbjct: 412 QEQEAKMWRQEEKIREQEEKIREQEK---------------KMWRQEEKIHEQEKIREEE 456
Query: 227 QQQRRE---RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER 283
++Q +E RQ+ +E+EE WR++E + +E+ + QEE+ RQ E ++E+ K+
Sbjct: 457 KRQEQEEMWRQEEKIREQEE-IWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEE--KIRE 513
Query: 284 QELRRERQEEE--QQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE--RREQQL 339
QE + RQEE+ +Q++++R +++ R+QEE +EQ+E+ EQ+E+ ++QE+ R+E+++
Sbjct: 514 QEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKI 573
Query: 340 RREQEERREQQLR-REQEEERREQQLR-REQEEERREQQLRREQQLRREQQLRREQQLRR 397
R ++E+ REQ+ + REQEE+ EQ+ + REQEE +EQ+ E+ +E+++ +++ +
Sbjct: 574 REQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQE---EKMWEQEEKMCEQEEKMQ 630
Query: 398 EQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434
EQ E+++RR+++ EQ++R QQ + QE + H
Sbjct: 631 EQ----EEKMRRQEEKMWEQEVRLRQQEEKMQEHQEH 663
Score = 143 bits (361), Expect = 1e-33
Identities = 123/484 (25%), Positives = 258/484 (53%), Gaps = 64/484 (13%)
Query: 1479 HRQERDRKFLEEEQQLRRQERDRKFR------------EQELRSQEPERKFLEEEQQ--L 1524
H E ++K + Q+ R+E + + + L + K LE E + +
Sbjct: 105 HSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLI 164
Query: 1525 HRQQRQRKFLQEEQQLRRQERGQQRRQDR--DRKFREEEQLRQEREEQQLSRQERDRKFR 1582
R KF E +Q Q+++ DR + +E + L E ++ +E K
Sbjct: 165 SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNA 224
Query: 1583 LEEQKVRRQEQERKFME-DEQQLRRQEG-------QQQLRQERDRKFREDEQLLQEREEQ 1634
++K++ E E+ ++ + ++L+R+ QQQL+ E D +E + + + + Q
Sbjct: 225 KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284
Query: 1635 QLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFR 1694
+ +R ++E ++ RQE + Q + + K +E+E+ ++E EE + +E++ K R
Sbjct: 285 VEENELWNRLNQQQEEKMWRQEEKIQ---EWEEKIQEQEEKIREQEE---KIREQEEKMR 338
Query: 1695 -------EEEQQLRRQ-----ERERKF--LQE---EQQLRRQELERKFREEEQLRQETEQ 1737
E+E+++RRQ E+E K L+E E++ + +ELE K E+E++R++ E+
Sbjct: 339 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEK 398
Query: 1738 EQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQE---REEQQLRS---- 1790
Q + R ++ +E++ + R+E+++R QE + +E++ RQE E++++R
Sbjct: 399 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR 458
Query: 1791 QESDRKFREEEQLRQE----REEQQLRPQQRDGKYR---WEEEQLQLEEQEQRLRQERDR 1843
QE + +R+EE++R++ R+++++ Q++ K W +E+ ++ +QE+++R++ ++
Sbjct: 459 QEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEE-KMHDQEEKIREQEEK 517
Query: 1844 QYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKS 1903
+R EE+ QE+ RE++E +E+E+ QE+E K+ E+ + Q++E+ R RQ +I+
Sbjct: 518 MWRQEEKIREQEEKIREQEEKIREQEE-MMQEQEEKMGEQEEKMQEQEKMR-RQEEKIRE 575
Query: 1904 QEGK 1907
QE K
Sbjct: 576 QEEK 579
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 232 bits (592), Expect = 2e-60
Identities = 174/647 (26%), Positives = 358/647 (55%), Gaps = 86/647 (13%)
Query: 583 EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642
+E RQ +L +E+ + + + +++++ E S E E++
Sbjct: 114 KETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQK 173
Query: 643 ----RQQQLRREQQER--------------------REQRLKREEEEERLEQRLKREHEE 678
Q+ LRRE + + + +K+ E E R + R H+
Sbjct: 174 ASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEAR--DLISRLHDS 231
Query: 679 ERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEK 738
+ EL + A + K + ++ +L E DA ++Y E E +EK
Sbjct: 232 WKFAGELEQALSAVATQ--KKKADRYIEELTKERDALSLELYRNTITDE------ELKEK 283
Query: 739 RRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQL 798
+ + +LQ E E++ Q +E +R K ER + L P + Q E
Sbjct: 284 NAKLQEKLQLVESEKSEIQLNVKELKR----------KLERAKLLL---PQQQLQAEADH 330
Query: 799 RAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQE 858
+E Q + + EE E R +++E+++ +EE++Q E +++QE+E+ ++E
Sbjct: 331 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW--RQEEKIQEWE--EKIQEQEEKIRE 386
Query: 859 DQERRRSQEQ--RRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQR- 915
+E+ R QE+ RR ++ W+ EE+ +R+ ++ K +E++R++++++ E+EE+++
Sbjct: 387 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKIREL 443
Query: 916 ----EEREKRRRQEQERQ----YREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967
E+EK R QE++RQ RE+E+ Q++E ++ R+E + R ++E+ R+ +++K+
Sbjct: 444 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE--QEEKMW 501
Query: 968 QKEEQLLGEEP--EKRRRQEREKKYREEEELQQEEE-----QLLREEREKRRRQEWERQY 1020
++EE++ +E E+ +RQE+E+ +R+EE+++++EE + + E+ EK R+QE E+ +
Sbjct: 502 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQE-EKMW 560
Query: 1021 RKKDELQQEEEQLLREE----REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQEL 1076
R+++++ +EE++ +E R++ +++E+E + RE+EE +E+E++ E+ E QE
Sbjct: 561 RQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQE- 619
Query: 1077 ERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQEL 1136
E+ +EE++Q++EE++ R+E + R E+E++ RE+EE +E+E++++E+ EK QE
Sbjct: 620 EKMCEQEEKMQEQEEKMRRQEEKIR---EQEKKIREQEEKIREQEEMMQEQEEKMWEQE- 675
Query: 1137 ERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQL 1183
E+ +EE++Q++EE++ R+E EK QE+ R ++EE++Q+ +E L
Sbjct: 676 EKMCEQEEKMQEQEEKMRRQE-EKMWEQEV-RLRQQEEKMQEHQEHL 720
Score = 230 bits (586), Expect = 1e-59
Identities = 162/580 (27%), Positives = 325/580 (56%), Gaps = 87/580 (15%)
Query: 812 PEEEEKEQRRRQ---RREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQ 868
PE+E+K + Q RRE E ++ + Q+ E L + +++ + R
Sbjct: 168 PEDEQKASHQHQEALRRELEAQVHTIRILT-CQKTELQMALYYSQHAVKQLEGEARDLIS 226
Query: 869 RRDQKWRW-----------------------QLEEERKRRRHTLYAKPALQEQLRKEQ-- 903
R W++ +L +ER LY E+L+++
Sbjct: 227 RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 286
Query: 904 -----QLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE------------ 946
QL++ E+ E+Q +E +R+ E+ + ++QLQ E + L +E
Sbjct: 287 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 346
Query: 947 -ERE---KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQ 1002
E E + +Q+ E+ +R+++K+Q+ EE++ +E + R E+E+K RE+EE + +E+
Sbjct: 347 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR---EQEEKIREQEEKMRRQEE 403
Query: 1003 LLREEREKRRRQE---WERQ--YRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQ 1057
++ E+ EK RRQE WE++ R+++E+ E+E+ +RE EK QE+ RE+EE +
Sbjct: 404 MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK---IREQEEKR 460
Query: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER---ERQCREEE 1114
QEEE++ RE +RQE E + ++EE +E+E+ +RE+ EK RQE E++ EE
Sbjct: 461 QEEEKI----REQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREE 516
Query: 1115 ELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEE 1174
E +QE+E++ R+E + R ++E+ +R++E++ ++EE++ ++E EK RQE E+ + +EE
Sbjct: 517 EKRQEQEEMWRQEEKIREQEEI---WRQKEKIHEQEEKIRKQE-EKMWRQE-EKMHDQEE 571
Query: 1175 ELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234
+++++EE++ R+E++ R E+E + RE+EE R++ + E++ E E++
Sbjct: 572 KIREQEEKVWRQEEKIR--EQEEKIREQEEKIREQEEMTQEQEEKMG------EQEEKMC 623
Query: 1235 VRDNKVYCKGRENEQFRQLEDSQLRDRQSQ-QDLQHLLGEQQERDREQERRRWQQRDRHF 1293
++ K+ +E E+ + ++ ++R+++ + ++ + + EQ+E +EQE + W+Q ++
Sbjct: 624 EQEEKM----QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 679
Query: 1294 PEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQE 1333
+EE+++ +E+K +R++ K E++ LR++ E+ + QE
Sbjct: 680 EQEEKMQEQEEK-MRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 226 bits (575), Expect = 2e-58
Identities = 148/504 (29%), Positives = 316/504 (62%), Gaps = 59/504 (11%)
Query: 143 EQERELAEGEEQSEKQERLEQRDRQRRDE---ELWRQRQEWQEREERRAE-EEQLQSCKG 198
E E+ L+ Q +K +R + + RD EL+R +E +E+ A+ +E+LQ +
Sbjct: 237 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 296
Query: 199 HETEEFPDEEQLRRR----ELL--------ELRRKGRE--------EKQQQRRERQDRVF 238
++E + ++L+R+ +LL E G+E + Q + E +R+
Sbjct: 297 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 356
Query: 239 QEEEEKEWRKRETVLRKEEEKLQEEEP---QRQRELQEEEEQLRKLE------RQELRRE 289
Q++EEK WR+ E + ++ EEK+QE+E +++ +++E+EE++R+ E +++RR+
Sbjct: 357 QQQEEKMWRQEEKI-QEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 415
Query: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQ 349
+ ++++++RR++++ ++EE+ RE +E+ EQ++ REQ+E+R+E++ REQE+R+EQ
Sbjct: 416 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ 475
Query: 350 QLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 409
+ + ++EE+ REQEE+ REQ E+++ R+++ EQ+ RE++ R+EQ
Sbjct: 476 EAKMWRQEEK-----IREQEEKIREQ----EEKMWRQEEKIHEQEKIREEEKRQEQ---- 522
Query: 410 EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQ 469
E+ R+E+++R ++++ R Q+E+ HEQ+ + ++E+++ R++E+ D + E+ E+ E+
Sbjct: 523 EEMWRQEEKIREQEEIWR-QKEKIHEQEEKIRKQEEKMWRQEEKMHD--QEEKIREQEEK 579
Query: 470 ERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL- 528
R+++ R+QEE+ RE+ K+ E+E E + +E+++ ++E+ EQ K QE+EE++
Sbjct: 580 VWRQEEKIREQEEKIREQEEKIREQE--EMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMR 637
Query: 529 --QQRLRSEQQLRREQEER---REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREE 583
++++R +++ REQEE+ +E++++ +EEK EQE + + + +E+ +++ ++EE
Sbjct: 638 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 697
Query: 584 ERRQQRLK-REQEERLEQRLKREE 606
+ +Q ++ R+QEE++++ + E
Sbjct: 698 KMWEQEVRLRQQEEKMQEHQEHLE 721
Score = 224 bits (570), Expect = 8e-58
Identities = 159/582 (27%), Positives = 325/582 (55%), Gaps = 64/582 (10%)
Query: 977 EPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE 1036
E E++ + ++ R E E Q ++L ++ + + + Q+ K +L+ E L+
Sbjct: 169 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVK-QLEGEARDLISR 227
Query: 1037 EREKRRLQ------------ERERQYREEEELQQEEEQLLGE-ERETRRRQELERQYRKE 1083
+ + ++++ R EEL +E + L E R T +EL+ + K
Sbjct: 228 LHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKL 287
Query: 1084 EE----LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ 1139
+E ++ E+ ++ E +R+ ER + +++LQ E + L +E + + L+ Q
Sbjct: 288 QEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK--LQAQ 345
Query: 1140 YREEEEV----QQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
E E QQ+EE++ R+E + QE E + +E+EE +E+E+ +RE++EK R++
Sbjct: 346 VEENELWNRLNQQQEEKMWRQE---EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 402
Query: 1196 ERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED 1255
E + +EE+++RQ+ ++E R + WE E++ + K++ E E+ R+ E+
Sbjct: 403 EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH----EQEKIREQEE 458
Query: 1256 SQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQ 1315
RQ ++ ++ +QE+ +EQE + W+Q ++ +EE++ +E+K ++ ++ +
Sbjct: 459 K----RQEEEKIR-----EQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHE 509
Query: 1316 EEKQLLREEREEKRRRQETDRKFREEEQLLQERE-----EQPLRRQERDRKFREEELRHQ 1370
+EK E+R+E+ + K RE+E++ +++E E+ +R+QE ++ +R+EE H
Sbjct: 510 QEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQE-EKMWRQEEKMH- 567
Query: 1371 EQGRKFLEEEQRLRRQERERKFLKEEQQLRCQE----REQQLRQDRDRKFREEEQQLSRQ 1426
+Q K E+E+++ RQ E K ++E+++R QE ++++ Q+++ K E+E+++ Q
Sbjct: 568 DQEEKIREQEEKVWRQ--EEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQ 625
Query: 1427 ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQER--- 1483
E K +E+E+++RRQ E K E+E+++R E+ K RE+E+++QE+EE+ ++E+
Sbjct: 626 E--EKMQEQEEKMRRQ--EEKIREQEKKIR-EQEEKIREQEEMMQEQEEKMWEQEEKMCE 680
Query: 1484 -DRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524
+ K E+E+++RRQE K EQE+R ++ E K E ++ L
Sbjct: 681 QEEKMQEQEEKMRRQE--EKMWEQEVRLRQQEEKMQEHQEHL 720
Score = 216 bits (549), Expect = 2e-55
Identities = 163/590 (27%), Positives = 326/590 (55%), Gaps = 66/590 (11%)
Query: 908 EEEEELQREEREKRRRQEQERQY--------REEEQLQQEEEQLLREEREKRRRQERERQ 959
E+E++ + +E RR+ + + + + E Q+ Q ++ E R R
Sbjct: 169 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 228
Query: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQ 1019
+ K + E+ L +K++ R EEL +E + L E R + +
Sbjct: 229 HDSWKFAGELEQALSAVATQKKKAD------RYIEELTKERDAL---SLELYRNTITDEE 279
Query: 1020 YRKKDELQQEEEQLLREER--------EKRRLQERERQYREEEELQQEEEQLLGEERET- 1070
++K+ QE+ QL+ E+ E +R ER + +++LQ E + L G+E ++
Sbjct: 280 LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHL-GKELQSV 338
Query: 1071 --RRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREER 1128
+ + ++E QQ+EE++ R+E + QE E + +E+EE +E+E+ +RE+
Sbjct: 339 SAKLQAQVEENELWNRLNQQQEEKMWRQE---EKIQEWEEKIQEQEEKIREQEEKIREQE 395
Query: 1129 EKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQEL----ERQYREEEELQQEEEQLL 1184
EK RRQE E + +EE+++++EE + +E + RR++E+ E + RE EE E+E+ +
Sbjct: 396 EKMRRQE-EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK-I 453
Query: 1185 REEQEKRRQE---RERQYREEEE--LQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNK 1239
RE++EKR++E RE++ R+E+E + RQ+ K R ++E R + W E++ ++
Sbjct: 454 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKI 513
Query: 1240 VYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQL 1299
+ R+ ++ ++ ++R+++ + + EQ+E+ R+QE + W+Q ++ +EE++
Sbjct: 514 REEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKI 573
Query: 1300 EREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERD 1359
RE++++ R++ K +E+++ +RE+ E K RE+E++ QE+EE + E++
Sbjct: 574 -REQEEKVWRQEEKIREQEEKIREQEE----------KIREQEEMTQEQEE---KMGEQE 619
Query: 1360 RKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREE 1419
K E+E + QEQ K +E+++R E+E+K ++E+++R QE ++ Q+++ K E+
Sbjct: 620 EKMCEQEEKMQEQEEKMRRQEEKIR--EQEKKIREQEEKIREQE---EMMQEQEEKMWEQ 674
Query: 1420 EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQL 1469
E+++ QE K +E+E+++RRQ E K E+E +LRQ+ + +E L
Sbjct: 675 EEKMCEQE--EKMQEQEEKMRRQ--EEKMWEQEVRLRQQEEKMQEHQEHL 720
Score = 215 bits (547), Expect = 4e-55
Identities = 175/631 (27%), Positives = 331/631 (52%), Gaps = 113/631 (17%)
Query: 1292 HFPEEEQLEREEQKEAKRRDRKSQEE-----------------------KQLLREEREEK 1328
H PE+EQ + +EA RR+ ++Q KQL E R+
Sbjct: 166 HSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLI 225
Query: 1329 RRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQER 1388
R ++ + E EQ L Q +++ DR EEL + + +E
Sbjct: 226 SRLHDSWKFAGELEQALSAVATQ---KKKADRYI--EELTKERDALSLELYRNTITDEEL 280
Query: 1389 ERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQE--RER 1446
+ K K +++L+ E E+ E QL+ +E RK + + +Q+ E
Sbjct: 281 KEKNAKLQEKLQLVESEKS------------EIQLNVKELKRKLERAKLLLPQQQLQAEA 328
Query: 1447 KFLEEEQQLRQERHRKFREEEQL---LQEREEQQLHRQER-----DRKFLEEEQQLRRQE 1498
L +E Q + + EE +L L +++E+++ RQE + K E+E+++R QE
Sbjct: 329 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 388
Query: 1499 RDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFR 1558
K REQE + + E E+E+++ RQ+ ++E+++RRQE ++++ R+
Sbjct: 389 --EKIREQEEKMRRQEEMMWEKEEKMRRQEEM--MWEKEEKMRRQEEMMWEKEEKIRELE 444
Query: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD 1618
E+ +++ EQ+ RQE + ++ EQ+ +RQEQE K E+++R QE +++R++ +
Sbjct: 445 EKMHEQEKIREQEEKRQEEE---KIREQE-KRQEQEAKMWRQEEKIREQE--EKIREQEE 498
Query: 1619 RKFREDEQL-LQEREEQQLHRQERDRKFLEEEPQLRRQE---REQQLRHDRDRKFREEEQ 1674
+ +R++E++ QE+ ++ RQE++ + +EE ++R QE R+++ H+++ K R++E+
Sbjct: 499 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE-KIREQEEIWRQKEKIHEQEEKIRKQEE 557
Query: 1675 LLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQE 1734
+ EE + +++ K RE+E+++ RQ E K ++E+++R Q E K RE+E++ QE
Sbjct: 558 KMWRQEE---KMHDQEEKIREQEEKVWRQ--EEKIREQEEKIREQ--EEKIREQEEMTQE 610
Query: 1735 TEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESD 1794
E++ ++E K+ E+E+ E+EE ++RRQE K RE+E+ +E+EE
Sbjct: 611 QEEKMGEQEE---KMCEQEEKMQEQEE-KMRRQE--EKIREQEKKIREQEE--------- 655
Query: 1795 RKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQ 1854
K RE+E++ QE+EE+ WE+E+ E++E+ QE
Sbjct: 656 -KIREQEEMMQEQEEKM-----------WEQEEKMCEQEEKMQEQE-------------- 689
Query: 1855 EKSRREEQELWQEEEQKRRQERERKLREEHI 1885
EK RR+E+++W++E + R+QE + + +EH+
Sbjct: 690 EKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 720
Score = 212 bits (539), Expect = 3e-54
Identities = 163/590 (27%), Positives = 326/590 (55%), Gaps = 89/590 (15%)
Query: 420 RREQQLRREQEEERHE------QKHEQERR----EQRLKREQEERRDWLKREEETERHEQ 469
+ ++ LRRE E + H QK E + + +K+ + E RD + R ++ +
Sbjct: 177 QHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAG 236
Query: 470 E---------RRKQQLKRDQEEERRER-WLKLE-------EEERREQQERREQQLRREQE 512
E +K++ R EE +ER L LE +EE +E+ + +++L+ +
Sbjct: 237 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 296
Query: 513 ERREQRLKRQEEEERLQQR--LRSEQQLRREQEERREQLLKREEEKRLEQERRE--QRLK 568
E+ E +L +E + +L++ L +QQL+ E + ++L + + + E E RL
Sbjct: 297 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 356
Query: 569 REQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEE 628
++QEE+ + R+EE+ Q+ ++ QE+ + R + E++ E++ RR++ + E+ E+
Sbjct: 357 QQQEEK----MWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 412
Query: 629 RRQQLLKSEEQEE-RRQQQLRREQQER-REQRLKREEEEERLEQRLKREHEEERREQELA 686
RRQ+ + E++E+ RRQ+++ E++E+ RE K E+E+ EQ KR+ EE+ REQE
Sbjct: 413 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 472
Query: 687 EEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESEL 746
+E++ + W+ E + +EQEEK R +E E
Sbjct: 473 QEQEAK------------MWRQEEKI--------------------REQEEKIREQE-EK 499
Query: 747 QWQEEERAHRQQ--QEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQ 804
W++EE+ H Q+ +EEE+R++ W+ EEK + + + EQ E+ + EE+
Sbjct: 500 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKM 559
Query: 805 QREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRR 864
R++ + ++EEK + + ++ R++E + E+EE++ RE+ ++++E+E+ QE +E+
Sbjct: 560 WRQEEKMHDQEEKIREQEEKVWRQEE-KIREQEEKI--REQEEKIREQEEMTQEQEEKMG 616
Query: 865 SQEQRR-DQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRR 923
QE++ +Q+ + Q +EE+ RR+ +E++R++++ ++E+EE+++ +E
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQ---------EEKIREQEKKIREQEEKIREQE---EMM 664
Query: 924 QEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQL 973
QEQE + E+E+ E+E+ ++E+ EK RRQE E+ + ++ +L+Q+EE++
Sbjct: 665 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE-EKMWEQEVRLRQQEEKM 713
Score = 211 bits (536), Expect = 7e-54
Identities = 182/608 (29%), Positives = 331/608 (54%), Gaps = 80/608 (13%)
Query: 115 QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ-SEKQERLEQRDRQRRDEEL 173
Q+ + E R+LE + R Q+ E ++A Q + KQ E RD R +
Sbjct: 172 QKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDS 231
Query: 174 WRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRER 233
W+ E ++ A +++ + + + EE + R+ L L E
Sbjct: 232 WKFAGELEQALSAVATQKK-------KADRYI-EELTKERDALSL-------------EL 270
Query: 234 QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEE 293
+EE KE K +EKLQ E ++ +E RKLER +L +Q+
Sbjct: 271 YRNTITDEELKEKNA------KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQL 324
Query: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR 353
+ + L +E Q + + Q E E R QQ+E E+ R+E++ + ++ +
Sbjct: 325 QAEADHLGKELQ----SVSAKLQAQVEENELWNRLNQQQE--EKMWRQEEKIQEWEEKIQ 378
Query: 354 EQEEERREQQLR-REQEEERREQQLRREQQLRREQQLRREQQL--RREQQLRREQQL--R 408
EQEE+ REQ+ + REQEE+ R Q+ E +E+++RR++++ +E+++RR++++
Sbjct: 379 EQEEKIREQEEKIREQEEKMRRQE---EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 435
Query: 409 REQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHE 468
+E+++R ++ EQ+ REQEE+R E E++ REQ KR+++E + W R E
Sbjct: 436 KEEKIRELEEKMHEQEKIREQEEKRQE---EEKIREQE-KRQEQEAKMW--------RQE 483
Query: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEE--RREQRLKRQEEEE 526
++ R+Q+ K ++EE+ R +EE+ EQ++ RE++ R+EQEE R+E++++ QEE
Sbjct: 484 EKIREQEEKIREQEEKMWR----QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 539
Query: 527 RLQQRLRSEQQLRREQEE---RREQLLKREEEKRLEQE----RREQRLKREQEERRDQLL 579
R ++++ +++ R+QEE R+E+ + +EEK EQE R+E++++ ++E+ R+Q
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQ-- 597
Query: 580 KREEERRQQRLKREQEERL---EQRLKREEVERLEQEER-REQRLKREEPEEERRQQLLK 635
E+ R Q+ + +EQEE++ E+++ +E + EQEE+ R Q K E E++ R+Q K
Sbjct: 598 -EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEK 656
Query: 636 SEEQEERRQQQLRR--EQQERR-EQRLKREEEEERLEQRLKREHEEE---RREQELAEEE 689
EQEE Q+Q + EQ+E+ EQ K +E+EE++ ++ ++ E+E R+++E +E
Sbjct: 657 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 716
Query: 690 QEQARERI 697
QE I
Sbjct: 717 QEHLEAAI 724
Score = 210 bits (534), Expect = 1e-53
Identities = 148/517 (28%), Positives = 306/517 (59%), Gaps = 41/517 (7%)
Query: 37 LEREFGAVLRRPHDP-KTVDLILELLDLDSNGRVDFNEFLLFIFKVAQACYYALGQATGL 95
LE E ++ R HD K + + L + + + ++ + K A L + T
Sbjct: 217 LEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTIT 276
Query: 96 DEE---KRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEE----PGQRRRQKRQEQEREL 148
DEE K A+ K L++ + E Q + R+LE P Q+ + + +EL
Sbjct: 277 DEELKEKNAKLQEKLQLVESEKSEI-QLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 335
Query: 149 ----AEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
A+ + Q E+ E L R Q+++E++WRQ ++ QE EE+ E+E+ + E +
Sbjct: 336 QSVSAKLQAQVEENE-LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE--KIREQEEKIR 392
Query: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE 264
EE++RR+E + ++ + +Q++ ++ + +EE W K E + EE+ ++E+
Sbjct: 393 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 452
Query: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
+ Q E ++EEE++R E+++ ++Q+ ++ R+++ R+QEE+ REQ+E+ Q
Sbjct: 453 IREQEEKRQEEEKIR---------EQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQ 503
Query: 325 QERREQQEERREQQLRREQEE--RREQQLRREQEEERREQQLRREQEEERREQQ---LRR 379
+E+ +QE+ RE++ R+EQEE R+E+++ REQEE R+++ EQEE+ R+Q+ R+
Sbjct: 504 EEKIHEQEKIREEEKRQEQEEMWRQEEKI-REQEEIWRQKEKIHEQEEKIRKQEEKMWRQ 562
Query: 380 EQQLRREQQLRREQQ---LRREQQLRREQQLRREQQ--LRREQQLRREQQLRR-EQEEER 433
E+++ +++ REQ+ R+E+++R +++ REQ+ +R ++++ +EQ+ + EQEE+
Sbjct: 563 EEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM 622
Query: 434 HEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEE 493
EQ+ + + +E++++R++E+ R+ K+ E E E+ R ++++ ++QEE+ E+ K+ E
Sbjct: 623 CEQEEKMQEQEEKMRRQEEKIREQEKKIREQE--EKIREQEEMMQEQEEKMWEQEEKMCE 680
Query: 494 EERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530
+E E+ + +E+++RR++E+ EQ ++ +++EE++Q+
Sbjct: 681 QE--EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 715
Score = 209 bits (533), Expect = 2e-53
Identities = 169/599 (28%), Positives = 329/599 (54%), Gaps = 85/599 (14%)
Query: 1119 EEEQLLREEREKRRRQELERQYR-------EEEEVQQE--EEQLLREEPEKRRRQELERQ 1169
E+EQ + ++ R+ELE Q ++ E+Q Q ++ E R + R
Sbjct: 169 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 228
Query: 1170 YREEEELQQEEEQLLREEQEKRRQER--ERQYREEEELQRQKRKQRYRDED-QRSDLKWQ 1226
+ + + E+ L +K++ +R E +E + L + + DE+ + + K Q
Sbjct: 229 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 288
Query: 1227 WEPEKENAVRDNKVYCKGRENEQFRQLEDSQLR--DRQSQQDLQHL----------LGEQ 1274
EK V K + E R+LE ++L +Q Q + HL L Q
Sbjct: 289 ---EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 345
Query: 1275 QERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQET 1334
E + R QQ ++ + +EE+++ E+K + ++ K +E+++ +RE+ E+ RR++E
Sbjct: 346 VEENELWNRLNQQQEEKMWRQEEKIQEWEEK-IQEQEEKIREQEEKIREQEEKMRRQEEM 404
Query: 1335 ----DRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERER 1390
+ K R +E+++ E+EE+ +RRQE +EE++R E+ + E++++R QE +R
Sbjct: 405 MWEKEEKMRRQEEMMWEKEEK-MRRQEEMMWEKEEKIRELEEK---MHEQEKIREQEEKR 460
Query: 1391 KFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQE----RER 1446
+ EE+++R EQ+ RQ+++ K +E+++ +E++ K RE+E+++ RQE +
Sbjct: 461 Q---EEEKIR----EQEKRQEQEAKMWRQEEKI--REQEEKIREQEEKMWRQEEKIHEQE 511
Query: 1447 KFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ 1506
K EEE+ RQE+ +R+EE++ RE++++ RQ+ K E+E+++R+QE K Q
Sbjct: 512 KIREEEK--RQEQEEMWRQEEKI---REQEEIWRQK--EKIHEQEEKIRKQE--EKMWRQ 562
Query: 1507 ELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE 1566
E + + E K E+E+++ RQ + K ++E+++R QE K RE+E++ QE
Sbjct: 563 EEKMHDQEEKIREQEEKVWRQ--EEKIREQEEKIREQE----------EKIREQEEMTQE 610
Query: 1567 REEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQ 1626
+EE+ ++E ++ EQ+ + QEQE K E+++R QE +++R E++ K RE E+
Sbjct: 611 QEEKMGEQEE-----KMCEQEEKMQEQEEKMRRQEEKIREQE--KKIR-EQEEKIREQEE 662
Query: 1627 LLQEREEQQLHRQER----DRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEE 1681
++QE+EE+ ++E+ + K E+E ++RRQE + +++ + R++E+ +QE +E
Sbjct: 663 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM---WEQEVRLRQQEEKMQEHQE 718
Score = 205 bits (522), Expect = 3e-52
Identities = 158/529 (29%), Positives = 303/529 (57%), Gaps = 82/529 (15%)
Query: 273 EEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
E E+ L + Q+ + +R EE ++R +L R + +++ + Q++ + +
Sbjct: 237 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 296
Query: 333 ERREQQLRREQEERR---------EQQLRREQEEERREQQ-----LRREQEEER---REQ 375
E+ E QL ++ +R+ +QQL+ E + +E Q L+ + EE R
Sbjct: 297 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 356
Query: 376 QLRREQQLRREQQLRR-EQQLRREQQLRREQQLR---REQQLRREQQLRREQQLRREQEE 431
Q + E+ R+E++++ E++++ +++ REQ+ + +E+++RR++++ E++ + ++E
Sbjct: 357 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 416
Query: 432 ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKL 491
E +K E+ RR++ + E+EE+ RE E + HEQE+ ++Q ++ QEEE K+
Sbjct: 417 EMMWEKEEKMRRQEEMMWEKEEKI----RELEEKMHEQEKIREQEEKRQEEE------KI 466
Query: 492 EEEERREQQER---REQQLRREQEER---REQRLKRQEEEERLQQRLRSEQQLRREQEER 545
E+E+R++QE R+++ REQEE+ +E+++ RQEE+ Q+++R E++ R+EQEE
Sbjct: 467 REQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEK-RQEQEE- 524
Query: 546 REQLLKREEEKRLEQER--REQRLKREQEERRDQLLKREEER--RQQRLKREQEERL--- 598
+ R+EEK EQE R++ EQEE+ ++++EE+ RQ+ +QEE++
Sbjct: 525 ----MWRQEEKIREQEEIWRQKEKIHEQEEK----IRKQEEKMWRQEEKMHDQEEKIREQ 576
Query: 599 EQRLKREEVERLEQEER-REQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQ 657
E+++ R+E + EQEE+ REQ K E EE ++Q K EQEE+ +Q E+ + +E+
Sbjct: 577 EEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQ--EEKMQEQEE 634
Query: 658 RLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQS 717
+++R+EE+ R +++ RE EE+ REQE +EQE+ W+ E + ++
Sbjct: 635 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK-----------MWEQEEKMCEQEE 683
Query: 718 KVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRD 766
K+ QEQEEK RR+E E W++E R +Q+++ ++ ++
Sbjct: 684 KM-------------QEQEEKMRRQE-EKMWEQEVRLRQQEEKMQEHQE 718
Score = 204 bits (520), Expect = 5e-52
Identities = 162/589 (27%), Positives = 322/589 (54%), Gaps = 70/589 (11%)
Query: 1178 QEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRD 1237
++E++ + QE R+E E Q L QK + + L + K+
Sbjct: 169 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMA-------LYYSQHAVKQ----- 216
Query: 1238 NKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEE 1297
+G + +L DS + +Q L + ++++ DR E ++RD E
Sbjct: 217 ----LEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELT-KERDA-LSLEL 270
Query: 1298 QLEREEQKEAKRRDRKSQEEKQLLREER-------EEKRRRQETDRKFREEEQLLQEREE 1350
+E K ++ K QE+ QL+ E+ +E +R+ E + ++QL E +
Sbjct: 271 YRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADH 330
Query: 1351 QPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQ 1410
Q K + + ++ R ++E+++ RQE + +E + + QE+E+++R+
Sbjct: 331 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKI----QEWEEKIQEQEEKIRE 386
Query: 1411 DRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQL- 1469
++ K RE+E+++ RQE E+E+++RRQE E+E+++R++ + +EE++
Sbjct: 387 -QEEKIREQEEKMRRQEE--MMWEKEEKMRRQEE--MMWEKEEKMRRQEEMMWEKEEKIR 441
Query: 1470 -LQEREEQQLHRQERDRKFLEEE---QQLRRQERDRKFREQELRSQEPERKFLEEEQQLH 1525
L+E+ +Q +E++ K EEE +Q +RQE++ K QE + +E E K E+E+++
Sbjct: 442 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMW 501
Query: 1526 RQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQERE--EQQLSRQERDRKFRL 1583
RQ+ + + E++++R +E+ RQ+++ +R+EE++R++ E Q+ E++ K R
Sbjct: 502 RQEEK---IHEQEKIREEEK----RQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRK 554
Query: 1584 EEQKVRRQE-----QERKFMEDEQQLRRQE----GQQQLRQERDRKFREDEQLLQEREEQ 1634
+E+K+ RQE QE K E E+++ RQE Q++ +E++ K RE E++ QE+EE+
Sbjct: 555 QEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEK 614
Query: 1635 QLHRQER----DRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD 1690
++E+ + K E+E ++RRQE + + ++++K RE+E+ ++E EE QE++
Sbjct: 615 MGEQEEKMCEQEEKMQEQEEKMRRQEEKIR---EQEKKIREQEEKIREQEEMM---QEQE 668
Query: 1691 RKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQ 1739
K E+E+++ E+E K ++E+++RRQE E+ + +E +LRQ+ E+ Q
Sbjct: 669 EKMWEQEEKM--CEQEEKMQEQEEKMRRQE-EKMWEQEVRLRQQEEKMQ 714
Score = 203 bits (516), Expect = 2e-51
Identities = 162/607 (26%), Positives = 319/607 (52%), Gaps = 93/607 (15%)
Query: 999 EEEQLLREEREKRRRQEWERQYR-------KKDELQQ----EEEQLLREEREKRRLQERE 1047
E+EQ + ++ R+E E Q +K ELQ + + + E E R L R
Sbjct: 169 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISR- 227
Query: 1048 RQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQE-- 1105
+ + E EQ L +++ + R EEL +E + L E E
Sbjct: 228 --LHDSWKFAGELEQALSAVATQKKKAD-----RYIEELTKERDALSLELYRNTITDEEL 280
Query: 1106 RERQCREEEELQ---QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162
+E+ + +E+LQ E+ ++ +E +R+ E + ++++Q E + L +E
Sbjct: 281 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 340
Query: 1163 RQELERQYREEE---ELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQ 1219
+ L+ Q E E L Q++E+ + ++EK ++ E+ +EE+++ Q+ K R ++E
Sbjct: 341 K--LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 398
Query: 1220 RSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDR 1279
R + WE E E+ R+ E+ ++ E++E+ R
Sbjct: 399 RRQEEMMWEKE-----------------EKMRRQEE--------------MMWEKEEKMR 427
Query: 1280 EQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLL----REEREEKRRRQETD 1335
QE W++ ++ EE++ EQ++ + ++ K QEE+++ R+E+E K RQE
Sbjct: 428 RQEEMMWEKEEKIRELEEKMH--EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE-- 483
Query: 1336 RKFREEEQLLQEREEQPLRRQER---DRKFREEELRHQEQGRKFLEEEQRLRRQE----R 1388
K RE+E+ ++E+EE+ R++E+ K REEE R +++ + +E+++R QE +
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQE--EMWRQEEKIREQEEIWRQ 541
Query: 1389 ERKFLKEEQQLRCQE----REQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQER 1444
+ K ++E+++R QE R+++ D++ K RE+E+++ RQE K RE+E+++R QE
Sbjct: 542 KEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEE--KIREQEEKIREQEE 599
Query: 1445 ERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEE--EQQLRRQERDRK 1502
+ + E++++ QE+ K E+E+ + E+EE+ ++E+ R+ E+ EQ+ + +E++ K
Sbjct: 600 K---IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEK 656
Query: 1503 FREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQ 1562
REQE QE E K E+E+++ Q+ K ++E+++RRQE ++ +++ + R++E+
Sbjct: 657 IREQEEMMQEQEEKMWEQEEKMCEQEE--KMQEQEEKMRRQE---EKMWEQEVRLRQQEE 711
Query: 1563 LRQEREE 1569
QE +E
Sbjct: 712 KMQEHQE 718
Score = 201 bits (510), Expect = 8e-51
Identities = 157/559 (28%), Positives = 309/559 (55%), Gaps = 64/559 (11%)
Query: 1387 ERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVR----RQ 1442
E E+K + Q+ +E E Q+ R ++ E Q++ ++ E + R R
Sbjct: 169 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 228
Query: 1443 ERERKFLEEEQQ----LRQERHRKFREEEQLLQERE--EQQLHR--------QERDRKFL 1488
KF E +Q + ++ + R E+L +ER+ +L+R +E++ K
Sbjct: 229 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 288
Query: 1489 EEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQ 1548
E+ Q + ++ + + +EL+ + K L +QQL Q +E Q + + + Q
Sbjct: 289 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQL--QAEADHLGKELQSVSAKLQAQV 346
Query: 1549 RRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQE 1608
+ + ++++ + R+E+++ QE + K + +E+K+R EQE K E E+++RRQE
Sbjct: 347 EENELWNRLNQQQEEKMWRQEEKI--QEWEEKIQEQEEKIR--EQEEKIREQEEKMRRQE 402
Query: 1609 GQQQLRQERDRKFREDEQLLQEREEQQLHRQE----RDRKFLEEEPQLRRQE--REQQLR 1662
++ E++ K R E+++ E+EE+ ++E ++ K E E ++ QE REQ+ +
Sbjct: 403 ---EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 459
Query: 1663 HDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQE----RERKFLQEEQQLR- 1717
+ K RE+E+ +EQ+ + ++ K RE+E+++R QE R+ + + E++++R
Sbjct: 460 RQEEEKIREQEKR----QEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIRE 515
Query: 1718 ---RQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQER----D 1770
RQE E +R+EE++R EQE++ RQ+ KI E+E+ ++EE+ R++E+ +
Sbjct: 516 EEKRQEQEEMWRQEEKIR---EQEEIWRQKE--KIHEQEEKIRKQEEKMWRQEEKMHDQE 570
Query: 1771 RKFREEEQL--RQERE--EQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEE 1826
K RE+E+ RQE + EQ+ + +E + K RE+E++ QE+EE+ +++ K +EE
Sbjct: 571 EKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKM---GEQEEKMCEQEE 627
Query: 1827 QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIR 1886
++Q EQE+++R++ ++ E++ QE+ RE++E+ QE+E+K E+E K+ E+ +
Sbjct: 628 KMQ--EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK-MWEQEEKMCEQEEK 684
Query: 1887 RQQKEEQRHRQVGEIKSQE 1905
Q++EE+ RQ ++ QE
Sbjct: 685 MQEQEEKMRRQEEKMWEQE 703
Score = 201 bits (510), Expect = 8e-51
Identities = 165/569 (28%), Positives = 318/569 (55%), Gaps = 67/569 (11%)
Query: 1368 RHQEQGRKFLEEEQRLRR----QERERKFLKEEQQLRCQEREQQLRQDRDR-----KFRE 1418
+HQE R+ LE + R Q+ E + Q ++ E + R R KF
Sbjct: 177 QHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAG 236
Query: 1419 E-EQQLSRQERDRKFREEEQQVRRQERERKFLE------EEQQLRQERHRKFREEEQLLQ 1471
E EQ LS +K + + +ER+ LE +++L+ E++ K +E+ QL++
Sbjct: 237 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELK-EKNAKLQEKLQLVE 295
Query: 1472 -EREEQQLHRQERDRKFLEEEQQLRRQERDRKFRE--QELRSQEPERKFLEEEQQLHRQQ 1528
E+ E QL+ +E RK + L +Q+ + +EL+S + + EE +L +
Sbjct: 296 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRL 355
Query: 1529 RQRKFLQEEQQLRRQERGQQ---RRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEE 1585
Q+ QEE+ R++E+ Q+ + Q+++ K RE+E+ +E+EE+ ++E + +E
Sbjct: 356 NQQ---QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWE---KE 409
Query: 1586 QKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDR----------KFREDEQLLQEREE-- 1633
+K+RRQE+ E E+++RRQE ++E+ R K RE E+ QE E+
Sbjct: 410 EKMRRQEE--MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 467
Query: 1634 QQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQL-LQEGEEQQLRRQERDRK 1692
+Q RQE++ K +E ++R E+E+++R ++ +R+EE++ QE ++ +RQE++
Sbjct: 468 EQEKRQEQEAKMWRQEEKIR--EQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEM 525
Query: 1693 FREEEQQLRRQE----RERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRK 1748
+R+EE ++R QE ++ K ++E+++R+QE E+ +R+EE++ +QE+ R++ +
Sbjct: 526 WRQEE-KIREQEEIWRQKEKIHEQEEKIRKQE-EKMWRQEEKMH---DQEEKIREQEEKV 580
Query: 1749 ILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQERE 1808
+EE++R EQ+ + +E++ K RE+E++ QE+EE + E + K E+E+ QE+E
Sbjct: 581 WRQEEKIR----EQEEKIREQEEKIREQEEMTQEQEE---KMGEQEEKMCEQEEKMQEQE 633
Query: 1809 EQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEE 1868
E+ R ++ + E++ ++ EQE+++R++ + EE+ QE+ E++E QE+
Sbjct: 634 EKMRRQEE-----KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 688
Query: 1869 EQKRRQERERKLREEHIRRQQKEEQRHRQ 1897
E+K R++ E+ +E RQQ+E+ + Q
Sbjct: 689 EEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 717
Score = 200 bits (509), Expect = 1e-50
Identities = 159/587 (27%), Positives = 316/587 (53%), Gaps = 58/587 (9%)
Query: 264 EPQRQRELQEEEEQLRKLERQ--ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321
E +++ Q +E R+LE Q +R ++ + Q L Q ++ E E R+
Sbjct: 169 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 228
Query: 322 REQQERREQQEERREQ-QLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRRE 380
+ + + E+ ++++ +R ++L +E++ E +EE +E+ + +
Sbjct: 229 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 288
Query: 381 QQLRREQQLRREQQLRREQ---QLRREQQLRREQQLRRE-----QQLRREQQLRREQEEE 432
++L+ + + E QL ++ +L R + L +QQL+ E ++L+ + Q EE
Sbjct: 289 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 348
Query: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLK-RDQEEE-RRERWLK 490
+++E+++ R++E+ ++W EE+ + E++ R+Q+ K R+QEE+ RR+ +
Sbjct: 349 NELWNRLNQQQEEKMWRQEEKIQEW---EEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 405
Query: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEE--RLQQRLRSEQQLRREQEERREQ 548
E+EE+ +QE E +E++ RR++ + ++EE+ L++++ ++++R ++E+R+E+
Sbjct: 406 WEKEEKMRRQE--EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE 463
Query: 549 LLKREEEKRLEQE----RREQRLKREQEERRDQ---LLKREEERRQQRLKREQEERLEQ- 600
RE+EKR EQE R+E++++ ++E+ R+Q + ++EE+ +Q RE+E+R EQ
Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQE 523
Query: 601 RLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLK 660
+ R+E + EQEE Q+ K E EE+ R+Q K QEE+ Q E+ +E+++
Sbjct: 524 EMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQ--EEKIREQEEKVW 581
Query: 661 REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVY 720
R+EE+ R ++ RE EE+ REQE +EQE+ K+
Sbjct: 582 RQEEKIREQEEKIREQEEKIREQEEMTQEQEE-------------------------KMG 616
Query: 721 SRPRKQ-EGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSER 779
+ K E + + QEQEEK RR+E ++ +E+E+ R+Q+E+ + ++ Q Q E+ E+
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKI--REQEKKIREQEEKIREQEEMMQEQEEKMWEQ 674
Query: 780 GRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRE 826
+ ++EQ E+ R EE+ ++ L ++EEK Q ++ E
Sbjct: 675 EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 721
Score = 197 bits (501), Expect = 8e-50
Identities = 161/654 (24%), Positives = 319/654 (48%), Gaps = 86/654 (13%)
Query: 434 HEQKHEQERREQRLKREQEERRDWLKREEETERHEQ----------ERRKQQLKRDQEEE 483
H H + +E + + +E+ T+ H Q + +K+++ E
Sbjct: 99 HLPTHPHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPE 158
Query: 484 RRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQE 543
E+ ++ + ++ LRRE E + ++ LQ L Q ++ E
Sbjct: 159 TTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLE 218
Query: 544 ERREQLLKREEEK-----RLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE---QE 595
L+ R + LEQ ++++ +R + L +E + L R E
Sbjct: 219 GEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE 278
Query: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEE-RRQQLLKSEEQEERRQQQLRREQQER 654
E E+ K +E +L + E+ E +L +E + + R +LL ++Q + L +E Q
Sbjct: 279 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 338
Query: 655 REQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADA 714
+L+ + EE L RL ++ EE+ QE +I +W+ +++ + +
Sbjct: 339 -SAKLQAQVEENELWNRLNQQQEEKMWRQE--------------EKIQEWEEKIQEQEE- 382
Query: 715 RQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQ-----EEEQRRDFTW 769
+ +E + + +EQEEK RR+E E+ W++EE+ RQ++ EE+ RR
Sbjct: 383 ---------KIREQEEKIREQEEKMRRQE-EMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 432
Query: 770 QWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREK 829
W+ EEK +++ + +REQ E++ E+ +++E+R +E+E + R++ + RE+
Sbjct: 433 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR---QEQEAKMWRQEEKIREQ 489
Query: 830 ELQFLEEEEQLQRRERAQQLQE---EEDGLQEDQERRRSQEQRRDQKWRWQ----LEEER 882
E + E+EE++ R+E QE EE+ QE +E R +E+ R+Q+ W+ + E+
Sbjct: 490 EEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQE 549
Query: 883 KRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQE----QERQYREEEQLQQ 938
++ R +E++ +++ ++E+EE++ R+E + R ++E QE + RE+E++ Q
Sbjct: 550 EKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQ 609
Query: 939 EEEQLLREEREKRRRQERERQYRKDKKLQQKE-------------------EQLLGEEPE 979
E+E+ + E+ EK QE + Q +++K +Q+E E+++ E+ E
Sbjct: 610 EQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 669
Query: 980 KRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQL 1033
K E+E+K E+EE QE+E+ +R + EK QE R ++++++Q+ +E L
Sbjct: 670 K--MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE-VRLRQQEEKMQEHQEHL 720
Score = 197 bits (500), Expect = 1e-49
Identities = 156/567 (27%), Positives = 318/567 (56%), Gaps = 52/567 (9%)
Query: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEE-ELQQEEEQLLREEREKRRRQELERQYR 1141
E++ + ++ LR E E + R C++ E ++ Q ++ E R + R +
Sbjct: 171 EQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHD 230
Query: 1142 EEEEVQQEEEQLLREEPEKRRRQE-LERQYREEEELQQE------EEQLLREEQEKRRQE 1194
+ + E+ L +K++ +E +E + L E ++ L+E+ K +++
Sbjct: 231 SWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEK 290
Query: 1195 RERQYREEEELQRQKRKQRYRDEDQRSDL-KWQWEPEKENAVRDNKVYCKGRENEQFRQL 1253
+ E+ E+Q ++ + + E + L + Q + E ++ ++ + + Q+
Sbjct: 291 LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ----AQV 346
Query: 1254 EDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRK 1313
E+++L +R +QQ + + Q+E+ +E E + +Q ++ +EE++ +E+K ++ +
Sbjct: 347 EENELWNRLNQQQ-EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 405
Query: 1314 SQEEKQLLRE-----EREEKRRRQ-----ETDRKFREEEQLLQERE---EQPLRRQERDR 1360
++E+++ R+ E+EEK RRQ E + K RE E+ + E+E EQ +RQE +
Sbjct: 406 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE-EE 464
Query: 1361 KFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEE 1420
K RE+E R QEQ K +E+++R QE E+ +EE+ R +E+ + + R+ + R+E+
Sbjct: 465 KIREQEKR-QEQEAKMWRQEEKIREQE-EKIREQEEKMWRQEEKIHEQEKIREEEKRQEQ 522
Query: 1421 QQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQERE-----E 1475
+++ RQE K RE+E+ R++E K E+E+++R++ + +R+EE++ + E E
Sbjct: 523 EEMWRQE--EKIREQEEIWRQKE---KIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQE 577
Query: 1476 QQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQ 1535
+++ RQE K E+E+++R QE K REQE +QE E K E+E+++ Q + K +
Sbjct: 578 EKVWRQE--EKIREQEEKIREQE--EKIREQEEMTQEQEEKMGEQEEKMCEQ--EEKMQE 631
Query: 1536 EEQQLRRQE---RGQQRR-QDRDRKFREEEQLRQEREEQQLSRQER--DRKFRLEEQKVR 1589
+E+++RRQE R Q+++ ++++ K RE+E++ QE+EE+ ++E+ +++ +++EQ+ +
Sbjct: 632 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 691
Query: 1590 RQEQERKFMEDEQQLRRQEGQQQLRQE 1616
+ QE K E E +LR+QE + Q QE
Sbjct: 692 MRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 187 bits (474), Expect = 1e-46
Identities = 144/565 (25%), Positives = 304/565 (53%), Gaps = 35/565 (6%)
Query: 354 EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQ-LRREQQLRREQQLRREQQ 412
++ + ++ LRRE E + ++ Q+ + L Q +++ + R+ R
Sbjct: 172 QKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDS 231
Query: 413 LRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR 472
+ +L EQ L +++ ++ +E ++R E R+ + EE E++ + +
Sbjct: 232 WKFAGEL--EQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQE 289
Query: 473 KQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ------RLKRQEEEE 526
K QL ++ E + +L+ + R + +QQL+ E + ++ +L+ Q EE
Sbjct: 290 KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN 349
Query: 527 RLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER--REQRLK-REQEE---RRDQLL- 579
L RL +Q+ E+ R+E+ ++ EEK EQE REQ K REQEE R+++++
Sbjct: 350 ELWNRLNQQQE---EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 406
Query: 580 -KREEERRQQRLKREQEERLEQRL-----KREEVERLEQEERREQRLKREEPEEERRQQL 633
K E+ RRQ+ + E+EE++ ++ K E++ LE++ +++++ +E E+RQ+
Sbjct: 407 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE---EKRQEE 463
Query: 634 LKSEEQEERRQQQLR--REQQERREQRLKREEEEERLEQRLKREHEEER-REQELAEEEQ 690
K EQE+R++Q+ + R++++ REQ K E+EE++ ++ ++ HE+E+ RE+E +E++
Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQE 523
Query: 691 EQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQE 750
E R+ K R + W+ + + ++ K+ + K Q + +E++ R + E W++
Sbjct: 524 EMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ 583
Query: 751 EERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRF 810
EE+ R+Q+E+ + ++ + Q E E+ + + EQ E+ EE+ +R++
Sbjct: 584 EEKI-REQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEK 642
Query: 811 LPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRR 870
+ E+EK+ R ++ + RE+E E+EE++ +E +++ E+E+ +QE +E+ R QE++
Sbjct: 643 I-REQEKKIREQEEKIREQEEMMQEQEEKMWEQE--EKMCEQEEKMQEQEEKMRRQEEKM 699
Query: 871 DQKWRWQLEEERKRRRHTLYAKPAL 895
++ ++E K + H + + A+
Sbjct: 700 WEQEVRLRQQEEKMQEHQEHLEAAI 724
Score = 164 bits (416), Expect = 6e-40
Identities = 138/513 (26%), Positives = 268/513 (52%), Gaps = 71/513 (13%)
Query: 1434 EEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQ 1493
E+EQ+ Q +E E E Q+ R ++ E + L+ + K LE E +
Sbjct: 169 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTEL------QMALYYSQHAVKQLEGEAR 222
Query: 1494 --LRRQERDRKFR---EQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQ 1548
+ R KF EQ L + ++K + ++ + ++R L E L R +
Sbjct: 223 DLISRLHDSWKFAGELEQALSAVATQKK--KADRYIEELTKERDALSLE--LYRNTITDE 278
Query: 1549 RRQDRDRKFREEEQL-RQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMED------- 1600
++++ K +E+ QL E+ E QL+ +E RK LE K+ +Q+ + D
Sbjct: 279 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRK--LERAKLLLPQQQLQAEADHLGKELQ 336
Query: 1601 ------EQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRR 1654
+ Q+ E +L Q+++ K E+ +QE EE+ QE++ K E+E ++R
Sbjct: 337 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI---QEQEEKIREQEEKIRE 393
Query: 1655 QEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQ 1714
QE K R +E+++ E EE+ R++E E+E+++RRQE + E+
Sbjct: 394 QEE----------KMRRQEEMMWEKEEKMRRQEEM---MWEKEEKMRRQEE----MMWEK 436
Query: 1715 QLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFR 1774
+ + +ELE K E+E++R++ E+ Q + R ++ +E++ + R+E+++R QE + +
Sbjct: 437 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 496
Query: 1775 EEEQLRQE---REEQQLRS----QESDRKFREEEQLRQERE--EQQLRPQQRDGKYRWEE 1825
EE+ RQE E++++R QE + +R+EE++R++ E Q+ + +++ K R +E
Sbjct: 497 EEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQE 556
Query: 1826 EQL-----QLEEQEQRLRQERDRQYRAEEQFATQEKSRRE------EQELWQEEEQKRRQ 1874
E++ ++ +QE+++R++ ++ +R EE+ QE+ RE EQE +E++++
Sbjct: 557 EKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMG 616
Query: 1875 ERERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
E+E K+ E+ + Q++EE+ RQ +I+ QE K
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKK 649
Score = 149 bits (375), Expect = 3e-35
Identities = 95/277 (34%), Positives = 183/277 (66%), Gaps = 27/277 (9%)
Query: 111 QDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEE----QSEK---QERLEQ 163
+++RQEE++ R E RQ +E R+ +K +EQE ++ E EE Q EK QE++ +
Sbjct: 457 EEKRQEEEKIR-EQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIRE 515
Query: 164 RDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGR 223
++++ EE+WRQ ++ +E+EE ++E++ HE EE++R++E R++ +
Sbjct: 516 EEKRQEQEEMWRQEEKIREQEEIWRQKEKI-----HE-----QEEKIRKQEEKMWRQEEK 565
Query: 224 EEKQQQR-RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLE 282
Q+++ RE++++V+++EE+ R++E +R++EEK++E+E Q + ++ EQ K+
Sbjct: 566 MHDQEEKIREQEEKVWRQEEKI--REQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMC 623
Query: 283 RQELRRERQEEE--QQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLR 340
QE + + QEE+ +Q++++R +++ R+QEE+ REQ+E +EQ+E+ +QEE+ +Q
Sbjct: 624 EQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 683
Query: 341 REQEERREQQLRREQEEERREQQLR-REQEEERREQQ 376
+ QE+ E+++RR QEE+ EQ++R R+QEE+ +E Q
Sbjct: 684 KMQEQ--EEKMRR-QEEKMWEQEVRLRQQEEKMQEHQ 717
Score = 100 bits (248), Expect = 2e-20
Identities = 69/244 (28%), Positives = 136/244 (55%), Gaps = 36/244 (14%)
Query: 97 EEKRARCDGK----ESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGE 152
EEK R + K E + ++ +++E + + ++ E+E R+++K EQE ++ + E
Sbjct: 497 EEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQE 556
Query: 153 E----QSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEE 208
E Q EK E++ R++ +E++WRQ ++ +E+EE+ E+E+ K E EE E+
Sbjct: 557 EKMWRQEEKMHDQEEKIREQ-EEKVWRQEEKIREQEEKIREQEE----KIREQEEMTQEQ 611
Query: 209 QLRRRE----LLELRRKGREEKQQQRRER-----QDRVFQEEEEKEWRKRETVLRKEEEK 259
+ + E + E K +E++++ RR+ Q++ +E+EEK +R++EE
Sbjct: 612 EEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEK--------IREQEEM 663
Query: 260 LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE 319
+QE+E + + ++ EQ K++ QE + RQEE+ EQ++R +Q+EE+ ++ +
Sbjct: 664 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW------EQEVRLRQQEEKMQEHQ 717
Query: 320 ERRE 323
E E
Sbjct: 718 EHLE 721
Score = 53.1 bits (126), Expect = 3e-06
Identities = 39/142 (27%), Positives = 72/142 (50%), Gaps = 29/142 (20%)
Query: 91 QATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAE 150
+ T EEK + K +++ QE +EE +R+ +K +EQE+++ E
Sbjct: 606 EMTQEQEEKMGEQEEKMCEQEEKMQE-------------QEEKMRRQEEKIREQEKKIRE 652
Query: 151 GEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQL 210
EE+ +QE + Q ++E++W Q ++ E+EE+ E+E+ K EE E+++
Sbjct: 653 QEEKIREQEEM----MQEQEEKMWEQEEKMCEQEEKMQEQEE----KMRRQEEKMWEQEV 704
Query: 211 RRRELLELRRKGREEKQQQRRE 232
R R+ +EEK Q+ +E
Sbjct: 705 RLRQ--------QEEKMQEHQE 718
Score = 52.4 bits (124), Expect = 4e-06
Identities = 30/114 (26%), Positives = 62/114 (54%), Gaps = 10/114 (8%)
Query: 91 QATGLDEEKRARCDGKESLLQD----RRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQER 146
Q + E++ C+ +E + + RRQEE R E + R+ EE+ ++ ++++E+
Sbjct: 611 QEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 670
Query: 147 ELAEGEEQSEKQERL-EQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGH 199
+ E+ E++E++ EQ ++ RR EE + W++ R +EE++Q + H
Sbjct: 671 MWEQEEKMCEQEEKMQEQEEKMRRQEE-----KMWEQEVRLRQQEEKMQEHQEH 719
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 231 bits (588), Expect = 7e-60
Identities = 394/1901 (20%), Positives = 804/1901 (42%), Gaps = 208/1901 (10%)
Query: 127 RQLEEEPGQRRRQKRQ-EQERELAEGEE--QSEKQERLEQRDRQRRDEELWRQRQEWQER 183
+QLEE + R Q + +Q +L E ++ Q + E++E R +QE + +
Sbjct: 357 KQLEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIENLTRMLVTSSSLTLQQELKAK 416
Query: 184 EERRA-----EEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVF 238
+RR + ++++ + P + +L + +E +
Sbjct: 417 RKRRVTWCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLLREIDESVCSESDVFSNTL 476
Query: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEE---Q 295
E EW +L QE L+ + + L L+ ++LR E++E E +
Sbjct: 477 DTLSEIEWNPATKLLN------QENIESELNSLRADYDNL-VLDYEQLRTEKEEMELKLK 529
Query: 296 QQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQ 355
++ L + L RK ++++ Q + + E Q L E + E L RE+
Sbjct: 530 EKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVE--LLREK 587
Query: 356 EEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 415
E++ ++ Q E + ++ + ++ + E E + +Q L + + + +R
Sbjct: 588 EDQIKKLQ---EYIDSQKLENIKMDLSYSLESI---EDPKQMKQTLFDAETVALDA--KR 639
Query: 416 EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ 475
E R + L +++ + ++Q + +L + Q E + K + + E+ Q +
Sbjct: 640 ESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKK--KMQVDLEKELQSAFNEI 697
Query: 476 LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRS- 534
K + + L E + +++L +E EE R EE L L+S
Sbjct: 698 TKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALR-----EEVILLSELKSL 752
Query: 535 ---EQQLRREQEERREQL--LKREEEKRLEQ----ERREQRLKREQEERRDQLLKREEER 585
++LR+E +++ E+L + E++K + E R Q L E + +D L +
Sbjct: 753 PSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNY 812
Query: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQE-ERRQ 644
+ + + + L +++ LE+ ER Q + E ++ L + + E +
Sbjct: 813 KSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKT 872
Query: 645 QQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS----- 699
Q+L+ + +E +E+ + E+ +E+LE R E RE+ L E+ +Q E +K+
Sbjct: 873 QELQEKTREVQERLNEMEQLKEQLENRDSTLQTVE-REKTLITEKLQQTLEEVKTLTQEK 931
Query: 700 -RIPKWQWQLESEADARQSKVY--------SRPRKQEGQRRRQEQEEKRRRRESELQWQE 750
+ + Q L+ E D +S ++ ++ + + ++ +E +S++ +
Sbjct: 932 DDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEV 991
Query: 751 EERAHRQQQEEEQRRDFTWQWQAEEKSE----RGRQRLSA----RPPLREQRERQLRAEE 802
H ++ E + +F + +K + + Q L+A + +QR+ +E
Sbjct: 992 SRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQE 1051
Query: 803 RQQREQRFLPEEEEKEQRRRQRR-------EREKELQFLEEEEQLQRRERAQ-------- 847
+ + +Q EKEQ + + E ++EL+ L +E + Q+ AQ
Sbjct: 1052 KNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKK 1111
Query: 848 --QLQEEEDGLQEDQE--RRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQ 903
+L D L E +E + +SQ+ + Q+ ++EE + + L+ +L+ ++
Sbjct: 1112 EGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKE 1171
Query: 904 QLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERE------ 957
L+ E E ++ E+ + +E ++ +E ++ ER+ R RE
Sbjct: 1172 LTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGL 1231
Query: 958 --RQYRKDKKLQQKEEQLLGEEPEKRRRQEREK---------------KYREEEELQQEE 1000
++ K + KE Q E ++ RR EK K +EE + EE
Sbjct: 1232 QTKEELKIAHIHLKEHQ---ETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEE 1288
Query: 1001 EQLLREEREKRRRQEW--ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREE-EELQ 1057
++LL +E QE E + + ++ L R E E+ RL E+ ++ +EE + L
Sbjct: 1289 QELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLT 1348
Query: 1058 QEEEQLLG-----EERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE 1112
+E + L E + + ++ + K +E Q ++EQ L K + E + E
Sbjct: 1349 KERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLN---MKEKDNETTKIVSE 1405
Query: 1113 EEELQQEEEQLLREE--------REKRRRQELERQYREEEEVQQEEEQLLREEPE-KRRR 1163
E+ + ++ LLR E R + E++ +E++++Q+ +E L E + K
Sbjct: 1406 MEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENI 1465
Query: 1164 QELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQR-QKRKQRYRDEDQRSD 1222
+E+ ++ E EE + L+E++E + R +E E+ QK+ + D+ Q
Sbjct: 1466 KEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKI 1525
Query: 1223 LKWQWEPEKENAVRDNKVYCKGRENEQF---RQLEDSQLRDRQSQQ-DLQHLLGEQQERD 1278
+ + E+ N + ++V K E +QF R+ +DS L+ +S+ +L + L E QE
Sbjct: 1526 QEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEI 1585
Query: 1279 REQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKF 1338
+ + + + + E Q+ER++ KE + +E Q + + ET K
Sbjct: 1586 QIMIKEK--EEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKM 1643
Query: 1339 REEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQ 1398
E E L ++ E Q L + E +R + + LEE +R +ER L+ ++
Sbjct: 1644 CEIEHLKEQFETQKLNLE----NIETENIRLTQILHENLEE---MRSVTKERDDLRSVEE 1696
Query: 1399 LRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQE 1458
ER+Q R+ R+ E+Q EE + V +E + E +LR
Sbjct: 1697 TLKVERDQLKENLRETITRDLEKQ-----------EELKIVHMHLKEHQ--ETIDKLRGI 1743
Query: 1459 RHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFL 1518
K E + ++ E + +D K EE + ++++ +LR E+
Sbjct: 1744 VSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDK 1803
Query: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERD 1578
Q + K ++ Q+L+ E Q K E ++ E +QL +Q +D
Sbjct: 1804 LSNMQKDLENSNAKLQEKIQELKANE-----HQLITLKKDVNETQKKVSEMEQLKKQIKD 1858
Query: 1579 RKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHR 1638
+ L + ++ +K E+ ++++ + +ERD R +E L ER++ +
Sbjct: 1859 QSLTLSKLEIENLNLAQKLHENLEEMK------SVMKERDNLRRVEETLKLERDQLKESL 1912
Query: 1639 QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREE--EQLLQEGEEQQLRRQERDRKFREE 1696
QE + LE + +L+ + + K RE+ E+ +Q + Q+ + +D + +++
Sbjct: 1913 QETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKD-ELQKK 1971
Query: 1697 EQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQE-RYRKILEEEQL 1755
Q+L+++E + ++E+ + +K E EQL+++ E + L Q R ++L
Sbjct: 1972 IQELQKKELQLLRVKEDVNMS----HKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKL 2027
Query: 1756 RPEREEQQLRRQERDRKFREEEQLRQEREE--QQLRSQESDRKFREEEQLRQEREEQQLR 1813
EE ++ +ERD R +E L+ ER++ LR E + ++R+ Q++
Sbjct: 2028 HESLEEIRIVAKERDELRRIKESLKMERDQFIATLR-----------EMIARDRQNHQVK 2076
Query: 1814 PQQR---DGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEK-SRREEQELWQEEE 1869
P++R DG+ E L E+ R+++ R ++ + + S E+E+ ++E
Sbjct: 2077 PEKRLLSDGQQHLTE---SLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKE 2133
Query: 1870 QKRRQERERK---LREEHIRRQQKEEQR-----HRQVGEIK 1902
R + L+ +HI + QR HR + ++K
Sbjct: 2134 LSMRVKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLK 2174
Score = 229 bits (583), Expect = 3e-59
Identities = 391/2016 (19%), Positives = 856/2016 (42%), Gaps = 276/2016 (13%)
Query: 91 QATGLDEEKRARCDGKESLLQDRRQEEDQRRFEP--RDRQLEEEPGQRRRQKRQEQEREL 148
+ LD ++ + E+L + +E ++ D QL + + +++ + + E+EL
Sbjct: 631 ETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKEL 690
Query: 149 AEGEEQSEK----------QERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKG 198
+ K ++ L + + + +L ++ + E E EE L S
Sbjct: 691 QSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLS--- 747
Query: 199 HETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWR----------- 247
E + P E + R+E+ + + E+ +D++F E KE R
Sbjct: 748 -ELKSLPSEVERLRKEIQD-----KSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKT 801
Query: 248 KRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQ-- 305
K + + K ++E Q + L + EQ K+ +E R QE + ++
Sbjct: 802 KDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSL 861
Query: 306 --LRRKQEEERREQQEERREQQERREQQEERREQQLRRE---QEERREQQLRREQEEERR 360
L+ + + +E QE+ RE QER + E+ +EQ R+ Q RE+ L E+ ++
Sbjct: 862 GALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTL 921
Query: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
E+ QE++ +Q L+ Q+ R+Q L+ + + ++QLR + ++ Q
Sbjct: 922 EEVKTLTQEKDDLKQ-LQESLQIERDQ-LKSDIHDTVNMNIDTQEQLRNALESLKQHQ-E 978
Query: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480
L+ + EE H +E + K E +++ + ++++ E + +K ++
Sbjct: 979 TINTLKSKISEEVSRNLHMEENTGET-KDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNE 1037
Query: 481 EEERRERWLKLEEEERREQQE-----RREQQLRREQEERREQRLKRQEEEERLQQRLRSE 535
E++ + L +E+ QQ ++QL+ + +E E ++ QEE L L+ +
Sbjct: 1038 IIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQ 1097
Query: 536 QQLRREQEE---RREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592
Q++ +++ ++E L R ++ E E + + ++ +E++ QLL +EE + + K
Sbjct: 1098 QEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKI 1157
Query: 593 EQEERLEQRLKREEV-------ERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ 645
+ E L+ LK +E+ ERLE ++ + + + + R+ L + ++ E +
Sbjct: 1158 NEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERD 1217
Query: 646 QLRREQQERREQRLKREEEEERLEQRLKREHEE----------ERREQELAEEEQEQARE 695
LR +E L+ +EE + LK EH+E E+ Q + ++ E++
Sbjct: 1218 HLRGYIREIEATGLQTKEELKIAHIHLK-EHQETIDELRRSVSEKTAQIINTQDLEKSHT 1276
Query: 696 RIKSRIPKWQWQLE--------SEADARQSKVY---SRPRKQEGQRRRQEQEEKRRRRES 744
+++ IP + E SE +++ + ++ + + E+ R E
Sbjct: 1277 KLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEK 1336
Query: 745 ELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQ 804
+ QEE ++ ++++ + + + ++ E R+ L+ + ++E+ L +E+
Sbjct: 1337 FQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKD 1396
Query: 805 QREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRR 864
+ + E E+ + + E E+ L + Q + + + + +E+D LQ QE +
Sbjct: 1397 NETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQ-ESHDEMKSVAKEKDDLQRLQEVLQ 1455
Query: 865 SQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL---LQEEEEEL-----QRE 916
S+ + + + + + + A L+EQ +L L E+E E+ Q E
Sbjct: 1456 SESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLE 1515
Query: 917 EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGE 976
+ + + + Y +EEQ ++ + +E+ +Q +E + KD LQ E ++L
Sbjct: 1516 AINDKLQNKIQEIYEKEEQFNIKQISEV-QEKVNELKQFKEHRKAKDSALQSIESKML-- 1572
Query: 977 EPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE 1036
E R +E QEE Q++ +E+E+ +R + Q ++D+L++ ++++ +
Sbjct: 1573 ----------ELTNRLQES--QEEIQIMIKEKEEMKRVQEALQI-ERDQLKENTKEIVAK 1619
Query: 1037 EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEE---EQL 1093
+E QE+E Q+ + + + +E++ E +++ E Q E ++ E Q+
Sbjct: 1620 MKES---QEKEYQFLKMTAVNETQEKMCEIEH---LKEQFETQKLNLENIETENIRLTQI 1673
Query: 1094 LREEPEKRRRQERERQ-CREEEELQQEEEQLLREEREKRRRQELERQ---------YREE 1143
L E E+ R +ER R EE + E L+E + ++LE+Q +E
Sbjct: 1674 LHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEH 1733
Query: 1144 EEVQQEEEQLLREEPEKRRRQELERQYREE----EELQQEEEQLLREEQEKRRQERERQY 1199
+E + ++ E+ + + + ++ + ++L+ +EE + K +QE +
Sbjct: 1734 QETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKL 1793
Query: 1200 REEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED---- 1255
R + K +D + S+ K Q + ++ A + K NE +++ +
Sbjct: 1794 RGIVSEKTDKLSNMQKDLEN-SNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQL 1852
Query: 1256 -SQLRDRQ---SQQDLQHL-LGEQQERDREQERRRWQQRD--RHFPEEEQLEREEQKEA- 1307
Q++D+ S+ ++++L L ++ + E+ + ++RD R E +LER++ KE+
Sbjct: 1853 KKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESL 1912
Query: 1308 ---KRRDRKSQEE----KQLLREERE--EKRRRQETDR----------------KFREEE 1342
K RD + Q+E + L +E +E +K R + +++ + +++
Sbjct: 1913 QETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKI 1972
Query: 1343 QLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQ 1402
Q LQ++E Q LR +E D +++ EQ +K E + + R F ++
Sbjct: 1973 QELQKKELQLLRVKE-DVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESL 2031
Query: 1403 EREQQLRQDRDRKFREEEQQLSRQERD------RKFREEEQQVRRQERERKFLEEEQQ-L 1455
E + + ++RD R +E + ERD R+ ++Q + + E++ L + QQ L
Sbjct: 2032 EEIRIVAKERDELRRIKESL--KMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHL 2089
Query: 1456 RQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPER 1515
+ K ++LL+ E H + +R L+ E+++ Q+ + L +
Sbjct: 2090 TESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMRVKANLSLPYLQT 2149
Query: 1516 KFLEE--------EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDR----DRKFREEEQL 1563
K +E+ + HR ++ K++ ++E+ + + D +++E L
Sbjct: 2150 KHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQKELL 2209
Query: 1564 RQEREEQQ----LSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDR 1619
+ + QQ SR+ RD K + + +E + F E E + E QQ L ++
Sbjct: 2210 IKIQHLQQDCDVPSRELRDLKLN-QNMDLHIEEILKDFSESEFPSIKTEFQQVLSNRKEM 2268
Query: 1620 KFREDEQLLQEREEQQLH---RQERDR--------------------KFLEEEPQLRRQE 1656
+E L + ++L ++E DR +F E + ++
Sbjct: 2269 TQFLEEWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEW 2328
Query: 1657 RE--QQLRHDRDRKFREEEQL---LQEGEEQQLRRQERDR-------------KFREEEQ 1698
+ + L+ ++ F+ + L L G + Q+ K RE E
Sbjct: 2329 EQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELEN 2388
Query: 1699 QLRRQE-----RERKFLQEEQQLRRQ-----ELERKFREEEQLRQETEQEQLRRQER--- 1745
L + +E K ++ +++L +L+ K E + ++T++ Q++
Sbjct: 2389 SLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVAL 2448
Query: 1746 ----YRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEE 1801
Y++ E E L+ + + L + + ++F +E + E Q +E R RE
Sbjct: 2449 GAKPYKE--EIEDLKMKLVKIDLEKMKNAKEFEKEISATKATVEYQ---KEVIRLLRENL 2503
Query: 1802 QLRQEREEQQLRPQQRDGKYR--------------------WEEEQLQLEEQEQRLRQER 1841
+ Q+ ++ + + D + + E ++LE++ +L+Q+
Sbjct: 2504 RRSQQAQDTSVISEHTDPQPSNKPLTCGGGSGIVQNTKALILKSEHIRLEKEISKLKQQN 2563
Query: 1842 DRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERE 1877
++ + + + + + E + W+E KR ++
Sbjct: 2564 EQLIKQKNELLSNNQHLSNEVKTWKERTLKREAHKQ 2599
Score = 186 bits (472), Expect = 2e-46
Identities = 336/1624 (20%), Positives = 677/1624 (41%), Gaps = 315/1624 (19%)
Query: 516 EQRLKRQEEEER-LQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR----- 569
E LKR +E L+++L R Q ++QL + EEK L Q+ + ++++
Sbjct: 342 EALLKRYRKEIMDLKKQLEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIENLTRML 401
Query: 570 --EQEERRDQLLKREEERRQ-------QRLKRE--------------QEERLEQRLKREE 606
Q LK + +RR ++K + +L L RE
Sbjct: 402 VTSSSLTLQQELKAKRKRRVTWCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLLREI 461
Query: 607 VERL---------------EQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQ 651
E + E E +L +E E L + +QLR E+
Sbjct: 462 DESVCSESDVFSNTLDTLSEIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEK 521
Query: 652 QERREQRLKRE---EEEERLEQRLKREHE--------------------------EERRE 682
+E E +LK + +E E LE++ K++ E E +
Sbjct: 522 EE-MELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSK 580
Query: 683 QELAEEEQEQAR-----------ERIKSRI---------PKWQWQLESEA-----DARQS 717
EL E+++Q + E IK + PK Q +A DA++
Sbjct: 581 VELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRE 640
Query: 718 KVYSRPRKQEGQRRRQEQEEKRRRRESELQ-WQEEERAHRQQQEEEQR------------ 764
+ R E + + +E ++ E+++Q +Q + A ++ Q + ++
Sbjct: 641 SAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKL 700
Query: 765 ---------RDFTWQWQAEEKSERGRQRLSARPPLREQRERQ-LRAEERQQREQRFLPEE 814
+D + E K ++ L+ +E E + LR E E + LP E
Sbjct: 701 TSLIDGKVPKDLLCNLELEGKITDLQKELN-----KEVEENEALREEVILLSELKSLPSE 755
Query: 815 EEKEQRRRQRREREKELQFLEEE------EQLQRRERAQQLQEE----EDGLQEDQERRR 864
E+ R++ +++ +EL + E E + + R Q L EE +D L Q +
Sbjct: 756 VER--LRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYK 813
Query: 865 SQEQR----------RDQKWRWQLEEERKRRRHTLYAKP----------ALQEQLRKEQQ 904
S +Q +QK++ LEE + + + AL+ +L + Q
Sbjct: 814 STDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQ 873
Query: 905 LLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE------EREKRRRQERER 958
LQE+ E+Q E + +EQ Q + E+ L+ E E K QE++
Sbjct: 874 ELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDD 933
Query: 959 QYRKDKKLQQKEEQL-----------LGEEPEKRRRQEREKKYRE-----EEELQQE-EE 1001
+ + LQ + +QL + + + R E K+++E + ++ +E
Sbjct: 934 LKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSR 993
Query: 1002 QLLREEREKRRRQEWERQ---YRKKDELQQEEEQLLREEREKRRLQERERQ----YREEE 1054
L EE + E++++ KK +L+ + Q L + + + E++R+ +E+
Sbjct: 994 NLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKN 1053
Query: 1055 ELQQEEEQLLGEERE--TRRRQELERQYRKEEELQQEEEQLLREEPEKRRR---QERERQ 1109
ELQQ E ++ E+ + T ++ +E +EEL +LL +E +K++ QE+
Sbjct: 1054 ELQQMLESVIAEKEQLKTDLKENIEMTIENQEEL-----RLLGDELKKQQEIVAQEKNHA 1108
Query: 1110 CREEEELQQEEEQLLR-EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELER 1168
++E EL + ++L EE+ K + Q+L Q++++QLL + E E+++
Sbjct: 1109 IKKEGELSRTCDRLAEVEEKLKEKSQQL----------QEKQQQLLNVQEE---MSEMQK 1155
Query: 1169 QYREEEELQQE--EEQLLREEQEKRRQERERQYREE-EELQRQKRKQRYRDEDQRSDLKW 1225
+ E E L+ E ++L E E R E ++ E EE++ ++++ E Q+S
Sbjct: 1156 KINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKS---- 1211
Query: 1226 QWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRR 1285
+E E+++ R++E + L+ ++ + + H+ ++ + ++ RR
Sbjct: 1212 -FETERDHL------------RGYIREIEATGLQTKE-ELKIAHIHLKEHQETIDELRRS 1257
Query: 1286 WQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREERE---EKRRRQETDRKFREEE 1342
++ + LE+ K QEE +L EE+E + ET E E
Sbjct: 1258 VSEKTAQIINTQDLEKSH--------TKLQEEIPVLHEEQELLPNVKEVSETQETMNELE 1309
Query: 1343 QLLQE---REEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL 1399
L ++ ++ L R E +R LR E+ ++ EE + L ++ K +KE ++
Sbjct: 1310 LLTEQSTTKDSTTLARIEMER------LRLNEKFQESQEEIKSLTKERDNLKTIKEALEV 1363
Query: 1400 RCQEREQQLRQDR---DRKFREEEQQLSRQERD----------RKFREEEQQVRRQERER 1446
+ + ++ +R+ ++EQ L+ +E+D +F+ ++ + R E E
Sbjct: 1364 KHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEM 1423
Query: 1447 KFL--------EEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQE 1498
L +E + + +E+ R +E L E ++ + + +E K LE E++L+
Sbjct: 1424 LGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAH 1483
Query: 1499 RDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFR 1558
K EQE E E+E ++ Q+Q + + ++ Q + QE ++ Q ++
Sbjct: 1484 CCLK--EQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQIS 1541
Query: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKV--------RRQEQERKFMEDEQQLRRQEGQ 1610
E ++ E ++ + R+ +D + E K+ QE+ + ++++++++R Q
Sbjct: 1542 EVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRV--Q 1599
Query: 1611 QQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFR 1670
+ L+ ERD+ ++++ + +E QE++ +FL+ QE+ ++ H ++ +F
Sbjct: 1600 EALQIERDQLKENTKEIVAKMKES----QEKEYQFLKMTAVNETQEKMCEIEHLKE-QFE 1654
Query: 1671 EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ 1730
++ L+ E + +R + + EE + + ++ + + ++E ++ R +L+ R
Sbjct: 1655 TQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLR---- 1710
Query: 1731 LRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRS 1790
ET L +QE + + L+ +E R K E ++++ E
Sbjct: 1711 ---ETITRDLEKQEELK--IVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDAL 1765
Query: 1791 QESDRKFREEEQL------RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQ 1844
+ D K +EE ++ Q+ +LR + + Q LE +L+++
Sbjct: 1766 KAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQEL 1825
Query: 1845 YRAEEQFATQEKSRREEQELWQEEEQKRRQERER-----KLREEHIRRQQKEEQRHRQVG 1899
E Q T +K E Q+ E EQ ++Q +++ KL E++ QK H +
Sbjct: 1826 KANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQK---LHENLE 1882
Query: 1900 EIKS 1903
E+KS
Sbjct: 1883 EMKS 1886
Score = 137 bits (345), Expect = 1e-31
Identities = 228/1092 (20%), Positives = 470/1092 (43%), Gaps = 100/1092 (9%)
Query: 894 ALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQ--EEEQLLREEREKR 951
AL ++ RKE L+++ EE+ E R + ++Q Q EE+ L Q + E++ R
Sbjct: 343 ALLKRYRKEIMDLKKQLEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIENLTRMLV 402
Query: 952 RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQL---LREER 1008
Q K +++ LG + K + ++ + + +L L E
Sbjct: 403 TSSSLTLQQELKAKRKRRVTWCLG-KINKMKNSNYADQFNIPTNITTKTHKLSINLLREI 461
Query: 1009 EKRRRQEWERQYRKKDELQQEE----EQLLREEREKRRLQERERQY----REEEELQQEE 1060
++ E + D L + E +LL +E + L Y + E+L+ E+
Sbjct: 462 DESVCSESDVFSNTLDTLSEIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEK 521
Query: 1061 EQL---LGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR---RQERERQCREEE 1114
E++ L E+ + + LER+ +K++E+Q E + K Q+ E + +
Sbjct: 522 EEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKV 581
Query: 1115 ELQQEEEQLLREEREKRRRQELER------QYREEEEVQQEEEQLLREEPEKRRRQELER 1168
EL +E+E +++ +E Q+LE E E ++ +Q L + + E
Sbjct: 582 ELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRES 641
Query: 1169 QYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWE 1228
+ E L+ +E+ ++E +Q + +L+ +K+ Q +++ +S E
Sbjct: 642 AFLRSENLELKEK--MKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFN---E 696
Query: 1229 PEKENAVRDNKV--------YCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDRE 1280
K ++ D KV +G+ + ++L + ++ + ++ ++ LL E + E
Sbjct: 697 ITKLTSLIDGKVPKDLLCNLELEGKITDLQKEL-NKEVEENEALREEVILLSELKSLPSE 755
Query: 1281 QERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE 1340
ER R + +D+ E + E+ K K + LL E + K T ++
Sbjct: 756 VERLRKEIQDKS-EELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKS 814
Query: 1341 EEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLR 1400
+Q Q + + +++ + EE R ++ +E Q+ + LK E +
Sbjct: 815 TDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKF---DSSLGALKTELSYK 871
Query: 1401 CQEREQQLRQDRDRKFREEEQQLSRQERDRKFRE-EEQQVRRQERERKFLEEEQQLRQER 1459
QE +++ R+ ++R E+ + + RD + E ++ E+ ++ LEE + L QE+
Sbjct: 872 TQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEK 931
Query: 1460 HRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLE 1519
+ +E L ER++ + + ++ ++QLR K ++ + + + K E
Sbjct: 932 DDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTL--KSKISE 989
Query: 1520 E-EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERD 1578
E + LH ++ + E QQ + G ++QD + K + L + ++ ++ Q+R
Sbjct: 990 EVSRNLHMEENTGETKDEFQQ---KMVGIDKKQDLEAK--NTQTLTADVKDNEIIEQQR- 1043
Query: 1579 RKFRLEEQKVRRQEQERKFMEDEQQLRRQ---------EGQQQLRQERDRKFREDEQLLQ 1629
+ F L ++K Q+ + +++QL+ E Q++LR D ++ E + Q
Sbjct: 1044 KIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQ 1103
Query: 1630 E-----REEQQLHR-----QERDRKFLEEEPQLRRQEREQQLRH------DRDRKFREEE 1673
E ++E +L R E + K E+ QL QE++QQL + + +K E E
Sbjct: 1104 EKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQL--QEKQQQLLNVQEEMSEMQKKINEIE 1161
Query: 1674 QLLQEGEEQQL-------RRQERDRKFREEEQQLRRQERERKFLQEEQ---QLRRQELER 1723
L E + ++L R E +K E ++++ +ERK L+E Q + R L
Sbjct: 1162 NLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRG 1221
Query: 1724 KFREEE----QLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFRE-EEQ 1778
RE E Q ++E + + +E I E + E+ Q + Q+ ++ + +E+
Sbjct: 1222 YIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEE 1281
Query: 1779 LRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLR 1838
+ EEQ+L + +E E +Q + R E E+L+L E+ Q +
Sbjct: 1282 IPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQ 1341
Query: 1839 QERDRQYRAEEQFATQEKSRREEQELWQE---EEQKRRQERERKLREEHIRRQQKEEQRH 1895
+E + + T +++ + + +E E + QE + K +E+ + ++K+ +
Sbjct: 1342 EEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSK-QEQSLNMKEKDNETT 1400
Query: 1896 RQVGEIKSQEGK 1907
+ V E++ + K
Sbjct: 1401 KIVSEMEQFKPK 1412
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 228 bits (581), Expect = 4e-59
Identities = 316/1226 (25%), Positives = 541/1226 (44%), Gaps = 138/1226 (11%)
Query: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQ----------------QEERREQQERREQ 330
RR Q+ +QQQ LR Q+ + R Q Q+E + + + Q
Sbjct: 828 RRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQ 887
Query: 331 QEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLR 390
+ + +QQ RE E + + + E+E R +QLR E E L E + R +
Sbjct: 888 KVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAE-------LCAEAEETRGRLAA 940
Query: 391 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKRE 450
R+Q+L E ++ E++ R+ Q +++ + QE E H + E R++ +L++
Sbjct: 941 RKQELELVVS-ELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKV 999
Query: 451 QEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRRE 510
E + K EE+ E + K +R E+R + EE + + + +L+ E
Sbjct: 1000 TTEAK-MKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYE 1058
Query: 511 -----QEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQ 565
E+R + K ++E E+L++RL E E +EQ++ E+++R E+ R +
Sbjct: 1059 ATIADMEDRLRKEEKGRQELEKLKRRLDG------ESSELQEQMV--EQQQRAEELRAQ- 1109
Query: 566 RLKREQEERRDQLLKREEE--RRQQRLK--REQEERLEQRLKREEVERLEQEERREQRLK 621
L R++EE + L + E+E R Q LK RE + L + + E ER+ + + +QR
Sbjct: 1110 -LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRD 1168
Query: 622 REEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERR 681
E E R + L+ QQ+LR ++++ + K EEE R+ + +E +R
Sbjct: 1169 LGEELEALRGE-LEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQE-LRQRH 1226
Query: 682 EQELAE--EEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKR 739
Q L E E+ EQAR R K K + LE+E ++++ S Q RQE E++R
Sbjct: 1227 GQALGELAEQLEQAR-RGKGAWEKTRLALEAEVSELRAELSSL------QTARQEGEQRR 1279
Query: 740 RRRESELQ-----WQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQR 794
RR E +LQ + ERA + E+ QR QAE ++ G + +R +
Sbjct: 1280 RRLELQLQEVQGRAGDGERARAEAAEKLQRA------QAELENVSGALNEAESKTIRLSK 1333
Query: 795 ERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEED 854
E L + E Q + + L +EE + + R R E + EQL EEE
Sbjct: 1334 E--LSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQL----------EEEA 1381
Query: 855 GLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQ 914
+E R Q + +WR + EEE A+ + Q L E+ E +
Sbjct: 1382 AARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVD 1441
Query: 915 REEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLL 974
R ER +RR Q Q+ ++ + E++++ E++ RK +L +E+ +
Sbjct: 1442 RLERGRRRLQ------------QELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAV 1489
Query: 975 GEEPEKRRRQEREKKYREEEELQ----QEEEQLLREEREKRR---RQEWERQYRKKDELQ 1027
E+R R E E + RE L EEEQ REE E++ R E E KD++
Sbjct: 1490 LRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVG 1549
Query: 1028 QEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQ 1087
+ +L ER R ++ R ++ + E++L E + + R E+ Q K Q
Sbjct: 1550 KSVHEL---ERACRVAEQAANDLR--AQVTELEDELTAAE-DAKLRLEVTVQALK---TQ 1600
Query: 1088 QEEEQLLREEPEKRRRQERERQCREEEELQQEE--EQLLREEREKRRRQELERQYREEEE 1145
E + R+E + RR++ +Q R+ E + EE ++ L K+ ELE +
Sbjct: 1601 HERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMAS 1660
Query: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLRE--EQEKRRQERERQ-YREE 1202
Q +E+ +++ ++ + +++ +RE EE + E++ + E EKR + E + R +
Sbjct: 1661 AGQGKEEAVKQ--LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ 1718
Query: 1203 EEL--QRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQ--- 1257
EEL + R+Q +D D+ +D K A+ + K +GR + +LE+ Q
Sbjct: 1719 EELAASDRARRQAQQDRDEMADEVANGNLSKA-AILEEKRQLEGRLGQLEEELEEEQSNS 1777
Query: 1258 --LRDRQSQQDLQ-----------HLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304
L DR + LQ + E R+Q R+ Q+ EE+ R
Sbjct: 1778 ELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARH 1837
Query: 1305 KE--AKRRDRKSQEEKQLLREEREEKRRRQETDR-KFREEEQLLQEREEQPLRRQERDRK 1361
K A + +Q E+QL +E RE + R + R +E +LQ EE+ + Q RD +
Sbjct: 1838 KMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRD-Q 1896
Query: 1362 FREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ 1421
+ LR ++ R+ E E+ R + R+ L+ E + + E R+ + R
Sbjct: 1897 LEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRG 1956
Query: 1422 QLSRQERD--RKFREEEQQVRRQERE 1445
L+ R + FR EE +E E
Sbjct: 1957 PLTFTTRTVRQVFRLEEGVASDEEAE 1982
Score = 223 bits (568), Expect = 1e-57
Identities = 286/1150 (24%), Positives = 501/1150 (43%), Gaps = 125/1150 (10%)
Query: 130 EEEPGQRRRQKRQE-QERELAEGEEQSEKQERLEQ--RDRQRRDEELWRQRQEWQEREER 186
++E Q R Q+ Q+ QE + E E Q R+ Q +R R E+L + + E EE
Sbjct: 875 QDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEET 934
Query: 187 R----AEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEE 242
R A +++L+ +EE+ R+ E +R QQ +E + + EE
Sbjct: 935 RGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRL-----QQHIQELEAHLEAEEG 989
Query: 243 EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR 302
++ + E V + + K EE+ + + + RKL L + +++++++
Sbjct: 990 ARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKS 1049
Query: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ 362
+LR K E + E+R ++E+ Q+ E+ +++L E E +EQ + ++Q E
Sbjct: 1050 LNKLRLKYEATIADM-EDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRA 1108
Query: 363 QLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 422
QL R++EE + ++ R Q L+ LR Q E Q + L E
Sbjct: 1109 QLGRKEEELQAALARAEDEGGARAQLLK---------SLREAQAALAEAQ----EDLESE 1155
Query: 423 QQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEE 482
+ R + E++R + E E L+ E E+ D ++E R ++E+ +LK+ EE
Sbjct: 1156 RVARTKAEKQRRDLGEELEA----LRGELEDTLDSTNAQQEL-RSKREQEVTELKKTLEE 1210
Query: 483 ERRERWLKLEEEERREQQERRE-----QQLRREQEERREQRLKRQEEEERLQQRLRSEQQ 537
E R ++E +R Q E +Q RR + + RL + E L+ L S Q
Sbjct: 1211 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1270
Query: 538 LRREQEERREQLLKREEE----------KRLEQERREQRLKREQEERRDQLLKREEERRQ 587
R+E E+RR +L + +E R E + QR + E E L E E +
Sbjct: 1271 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGAL--NEAESKT 1328
Query: 588 QRLKREQEERLEQRLKREEVERLEQEERREQ-----RLKREEPEEE-RRQQLLKSEEQEE 641
RL +E Q + + L QEE R + R++ E E R+QL + E
Sbjct: 1329 IRLSKELSSTEAQ---LHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARE 1385
Query: 642 RRQQQLRREQQERREQRLKREEEEERL----EQRLKREHEEERREQELAEEEQ-----EQ 692
R ++L+ Q + E R ++EEE L E R + E E Q LAE+ + E+
Sbjct: 1386 RAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLER 1445
Query: 693 ARERIKSRIP------KWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKR-----RR 741
R R++ + + Q QL S + +Q K +++ R +E +R R
Sbjct: 1446 GRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRE 1505
Query: 742 RESE-------LQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQR 794
RE+ L+ ++E R ++Q R + +++ + L + EQ
Sbjct: 1506 REARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQA 1565
Query: 795 ERQLRAEERQQREQRFLPEEEEKEQR---RRQRREREKELQFLEEEEQLQRRERAQQLQE 851
LRA+ + ++ E+ + + + + E++LQ +E + +RR+ A+QL++
Sbjct: 1566 ANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRD 1625
Query: 852 EEDGLQEDQERR-RSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE-- 908
E ++ D+ER+ R+ +K +LEE + + K +QLRK Q ++E
Sbjct: 1626 AE--VERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELW 1683
Query: 909 ---EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKK 965
EE REE + R+ ++R E ++ + +E+L +R +R+ Q+ + +
Sbjct: 1684 REVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVA 1743
Query: 966 LQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ--------EWE 1017
+ + E EKR+ + R + EE E +Q +LL + K Q E
Sbjct: 1744 NGNLSKAAILE--EKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE 1801
Query: 1018 RQYRKKDE--LQQEEEQL------LREEREKRRLQERERQYREEEELQQEEEQLLGEERE 1069
R + K E QQ E Q+ L EE R + + E +L Q EEQL E RE
Sbjct: 1802 RSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRE 1861
Query: 1070 TRRRQELERQYR---KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE 1126
+L R+ KE LQ EEE+ + ++ + + R + + +L++ EE+ R
Sbjct: 1862 RILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRA 1921
Query: 1127 EREKRRRQELERQYREEEEVQQEEEQLLREEPEKR---RRQELERQYREEEELQQEEEQL 1183
+ +RR Q RE E+V + E + RE R RR L R ++ + EE +
Sbjct: 1922 QAGRRRLQ------RELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGV 1975
Query: 1184 LREEQEKRRQ 1193
+E+ + Q
Sbjct: 1976 ASDEEAEEAQ 1985
Score = 208 bits (529), Expect = 5e-53
Identities = 302/1182 (25%), Positives = 521/1182 (44%), Gaps = 169/1182 (14%)
Query: 843 RERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQ---EQL 899
R Q+ Q+++ L+ Q + + R +W W+L + K LQ ++L
Sbjct: 828 RRAFQKRQQQQSALRVMQRNCAAYLKLRHWQW-WRLFTKVKPLLQVTRQDEVLQARAQEL 886
Query: 900 RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959
+K Q+L Q+ E+ E + R Q +E + R EQL+ E E E + R R+++
Sbjct: 887 QKVQELQQQSAREVG--ELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQE 944
Query: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQ 1019
+ + + E +GEE E R+ + EKK R ++ +Q+ E L EE R++ + E+
Sbjct: 945 L---ELVVSELEARVGEEEECSRQMQTEKK-RLQQHIQELEAHLEAEE-GARQKLQLEKV 999
Query: 1020 YRKKDELQQEEEQLLREEREKRRLQER---ERQYREEEELQQEEEQLLGEERETRRRQE- 1075
+ + EE+ LL E++ + +ER E + E EEE+ + + R + E
Sbjct: 1000 TTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEA 1059
Query: 1076 ----LERQYRKEEELQQEEEQLLRE---EPEKRRRQERERQCREEE---ELQQEEEQ--- 1122
+E + RKEE+ +QE E+L R E + + Q E+Q R EE +L ++EE+
Sbjct: 1060 TIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQA 1119
Query: 1123 -LLREEREKRRRQELERQYRE------EEEVQQEEEQLLREEPEKRRR---QELERQYRE 1172
L R E E R +L + RE E + E E++ R + EK+RR +ELE E
Sbjct: 1120 ALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGE 1179
Query: 1173 EEEL--QQEEEQLLREEQEKRRQERERQYREEEEL-QRQKRKQRYRDEDQRSDLKWQWEP 1229
E+ +Q LR ++E+ E ++ EE + + ++ R R +L Q E
Sbjct: 1180 LEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQ 1239
Query: 1230 EK--ENAVRDNKVYCKGRENE---QFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERR 1284
+ + A ++ + +E + L+ ++ Q ++ L+ L E Q R + ER
Sbjct: 1240 ARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERA 1299
Query: 1285 RWQQRDRHFPEEEQLEREE-------------QKEAKRRDRKSQEEKQLLREEREEKRRR 1331
R + ++ + +LE KE + + + ++LL+EE K
Sbjct: 1300 RAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLAL 1359
Query: 1332 QETDRKFREEEQLLQER-EEQPLRRQERDRKFREEELRHQEQGRKFLEE-------EQRL 1383
R E L+E+ EE+ R+ R+ + + + E R+ EE E+
Sbjct: 1360 GSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEAR 1419
Query: 1384 RRQERERKFL------KEEQQLRCQEREQQLRQDRDRKFREEEQQ------LSRQER--D 1429
RR RE + L K E R + ++L+Q+ D + EQQ L +++R D
Sbjct: 1420 RRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFD 1479
Query: 1430 RKFREEEQQVRR--QERER----------------KFLEEEQQLRQERHRKFR----EEE 1467
+ EE+ V R +ERER + LEEEQ+ R+E R+ R E E
Sbjct: 1480 QLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELE 1539
Query: 1468 QLLQEREE--QQLHRQERDRKFLEE-EQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524
LL +++ + +H ER + E+ LR Q + E EL + E + LE Q
Sbjct: 1540 ALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTE---LEDELTAAEDAKLRLEVTVQA 1596
Query: 1525 HRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKF--R 1582
+ Q +R R E G++RR+ ++ R+ E R E +Q+ +K
Sbjct: 1597 LKTQHERDL------QGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGE 1650
Query: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERD 1642
LEE K + + E +QLR+ + Q ++L +E EE + R+E
Sbjct: 1651 LEELKAQMASAGQGKEEAVKQLRKMQAQM-------------KELWREVEETRTSREEIF 1697
Query: 1643 RKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRR 1702
+ E E +L+ E E R +E+L ++ +Q+RD E ++
Sbjct: 1698 SQNRESEKRLKGLEAE---------VLRLQEELAASDRARRQAQQDRD----EMADEVAN 1744
Query: 1703 QERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQ-------- 1754
+ + EE +RQ R + EE+L +E +L +RYRK+L + +
Sbjct: 1745 GNLSKAAILEE---KRQLEGRLGQLEEELEEEQSNSEL-LNDRYRKLLLQVESLTTELSA 1800
Query: 1755 -----LRPEREEQQLRRQERDRKFR--EEEQLRQEREEQQLRSQESDRKFREEEQLRQER 1807
+ E QQL RQ ++ + R EE+ + R + + + ES + + EEQL QE
Sbjct: 1801 ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALES-KLAQAEEQLEQET 1859
Query: 1808 EEQQLRPQ-QRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQ 1866
E+ L + R + R +E LQ+EE+ + Q RD+ + + Q K + EE
Sbjct: 1860 RERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR-VKQLKRQLEE----A 1914
Query: 1867 EEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKG 1908
EEE R Q R+L+ E + E +R+V ++++ +G
Sbjct: 1915 EEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRG 1956
Score = 207 bits (528), Expect = 6e-53
Identities = 274/1193 (22%), Positives = 514/1193 (43%), Gaps = 138/1193 (11%)
Query: 218 LRRKGREEKQQQRR-----ERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE--PQRQRE 270
L R+ +++QQQ+ +R + + +W + T ++ + +++E R +E
Sbjct: 826 LARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQE 885
Query: 271 LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQ 330
LQ+ +E ++ R+ + + + +++R R +QLR E E + EE R + R+Q
Sbjct: 886 LQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRA--EAELCAEAEETRGRLAARKQ 943
Query: 331 QEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLR 390
+ E +L E E + + E++R +Q ++ + E+ R++ QL +
Sbjct: 944 ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEA 1003
Query: 391 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKRE 450
+ ++ + L +Q + ++ + + E + +EEE+ + ++ + + +
Sbjct: 1004 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1063
Query: 451 QEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQ---QL 507
E+R R+EE R E E+ K++L + E +E+ EQQ+R E+ QL
Sbjct: 1064 MEDR----LRKEEKGRQELEKLKRRLDGESSE---------LQEQMVEQQQRAEELRAQL 1110
Query: 508 RREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL 567
R++EE + + ++E Q L+S ++ + E +E L+ E R + E++ + L
Sbjct: 1111 GRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQED-LESERVARTKAEKQRRDL 1169
Query: 568 KREQEERRDQL---LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE 624
E E R +L L +++ R KREQE E+++ +EE R +E
Sbjct: 1170 GEELEALRGELEDTLDSTNAQQELRSKREQEV--------TELKKTLEEETRIHEAAVQE 1221
Query: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE 684
+ Q L + EQ E Q RR + + RL E E L L +
Sbjct: 1222 LRQRHGQALGELAEQLE----QARRGKGAWEKTRLALEAEVSELRAELS--------SLQ 1269
Query: 685 LAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES 744
A +E EQ R R++ ++ + Q R +G+R R E EK +R ++
Sbjct: 1270 TARQEGEQRRRRLELQLQEVQ-----------------GRAGDGERARAEAAEKLQRAQA 1312
Query: 745 ELQ------WQEEERAHRQQQE----EEQRRDFTWQWQAEEKSE-----RGRQRLSARPP 789
EL+ + E + R +E E Q D Q E +++ R R +
Sbjct: 1313 ELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAG 1372
Query: 790 LREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRER---- 845
LREQ E + A ER RE + + Q RR +E+E LE E+ +RR
Sbjct: 1373 LREQLEEEAAARERAGREL-----QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAE 1427
Query: 846 --AQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQ 903
Q+L E+ + + + RR +Q D LE++R+ L+++ RK
Sbjct: 1428 ALTQRLAEKTETVDRLERGRRRLQQELDDA-TMDLEQQRQ-------LVSTLEKKQRKFD 1479
Query: 904 QLLQEEEEELQR--EEREKRRRQEQERQ------YREEEQLQQEEEQLLREEREKRRRQE 955
QLL EE+ + R EERE+ + +ER+ R E+ Q+ E+L R+ R R E
Sbjct: 1480 QLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELE 1539
Query: 956 RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR---------- 1005
+ D E + E+ R + E+EL E+ LR
Sbjct: 1540 ALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKT 1599
Query: 1006 -EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLL 1064
ER+ + R E + R++ Q + ++ R+E K+R + + E EL++ + Q+
Sbjct: 1600 QHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMA 1659
Query: 1065 ----GEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEE 1120
G+E ++ ++++ Q KE + EE + REE + R+ +R E E+ + +
Sbjct: 1660 SAGQGKEEAVKQLRKMQAQ-MKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ 1718
Query: 1121 EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE 1180
E+L +R +R+ Q+ + +E + + E EKR+ + Q EE E +Q
Sbjct: 1719 EELAASDRARRQAQQDRDEMADEVANGNLSKAAILE--EKRQLEGRLGQLEEELEEEQSN 1776
Query: 1181 EQLLREEQEKRRQERERQYRE---EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRD 1237
+LL + K + E E E + R + E Q +L+ + E A
Sbjct: 1777 SELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARAR 1836
Query: 1238 NKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEE 1297
+K+ E++ +Q ++ Q+ + +L + R E +R ++ EE
Sbjct: 1837 HKMTIAALESKL------AQAEEQLEQETRERILSGKLVRRAE---KRLKEVVLQVEEER 1887
Query: 1298 QLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE 1350
++ + + + ++ + + ++ K+ L E EE R Q R+ + E + + E E
Sbjct: 1888 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAE 1940
Score = 207 bits (526), Expect = 1e-52
Identities = 266/1037 (25%), Positives = 461/1037 (44%), Gaps = 90/1037 (8%)
Query: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154
L+ E+ AR ++ L+ E ++FE D L E+ + ++R+ E LAE Q
Sbjct: 984 LEAEEGAR---QKLQLEKVTTEAKMKKFE-EDLLLLEDQNSKLSKERKLLEDRLAEFSSQ 1039
Query: 155 S-EKQERLEQRDRQRRDEE--LWRQRQEWQEREERRAEEEQLQSCKGHETEEFPD---EE 208
+ E++E+++ ++ R E + ++ E+ R E E+L+ E+ E + E+
Sbjct: 1040 AAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQ 1099
Query: 209 QLRRREL-LELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR 267
Q R EL +L RK E + R + + + K R+ + L + +E L+ E R
Sbjct: 1100 QQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVAR 1159
Query: 268 QRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ---EERREQ 324
+ E+Q R L +EL R E E +Q+LR K+E+E E + EE
Sbjct: 1160 TK----AEKQRRDL-GEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI 1214
Query: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
E Q+ +R Q E E+ EQ R + E+ L E E R E L Q R
Sbjct: 1215 HEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAE--LSSLQTAR 1272
Query: 385 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE 444
+E + RR R E QL+ Q + + R + + Q+ + E E +E E +
Sbjct: 1273 QEGEQRRR---RLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENV-SGALNEAESKT 1328
Query: 445 QRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERRE 504
RL +E L +E + E + R + E L+ + EE +ER
Sbjct: 1329 IRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAG 1388
Query: 505 QQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERRE 564
++L+ Q + E R +RQEEE L + ++ RR E L +R EK +R E
Sbjct: 1389 RELQTAQAQLSEWR-RRQEEE---AGALEAGEEARRRAAREAEALTQRLAEKTETVDRLE 1444
Query: 565 QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE 624
+ +R Q+E D + E++R+ +++ + +Q L E+ L E RE+
Sbjct: 1445 RGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGR 1504
Query: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE 684
E R L ++ E+E+ +++L R+ R R E E L K + + E E
Sbjct: 1505 EREARALSLTRALEEEQEAREEL------ERQNRALRAELEALLSS--KDDVGKSVHELE 1556
Query: 685 LAEEEQEQARERIKSRIPKWQWQLESEADAR-----QSKVYSRPRKQEGQRRRQEQEEKR 739
A EQA +++++ + + +L + DA+ + +++ Q R + EE+R
Sbjct: 1557 RACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERR 1616
Query: 740 RRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPL----REQRE 795
R+ +L+ E ER +E+R+ T A +K E + L A+ +E+
Sbjct: 1617 RQLAKQLRDAEVER-------DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAV 1669
Query: 796 RQLRAEERQQREQRFLPEE--EEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
+QLR + Q +E EE +E+ Q RE EK L+ LE A+ L+ +E
Sbjct: 1670 KQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE----------AEVLRLQE 1719
Query: 854 DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEEL 913
+ D+ RR++Q+ R +E + +K A+ E+ R+ + L + EEEL
Sbjct: 1720 ELAASDRARRQAQQDR---------DEMADEVANGNLSKAAILEEKRQLEGRLGQLEEEL 1770
Query: 914 QREEREKRRRQEQERQ-YREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQ 972
+ E+ ++ R+ + E L E L ER + E RQ + ++++Q+ +
Sbjct: 1771 EEEQSNSELLNDRYRKLLLQVESLTTE----LSAERSFSAKAESGRQ-QLERQIQELRGR 1825
Query: 973 LLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQ 1032
LGEE R + + E +L Q EEQL +E RE+ + R+ K+ ++
Sbjct: 1826 -LGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKR------LKE 1878
Query: 1033 LLREEREKRRLQERERQYREEEEL--QQEEEQLLGEERETRRRQELERQYRKE-EELQQE 1089
++ + E+RR+ ++ R E+ L +Q + QL E E R Q R+ ++E E++ +
Sbjct: 1879 VVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTES 1938
Query: 1090 EEQLLREEPEKRRRQER 1106
E + RE R R R
Sbjct: 1939 AESMNREVTTLRNRLRR 1955
Score = 126 bits (316), Expect = 2e-28
Identities = 153/619 (24%), Positives = 269/619 (43%), Gaps = 65/619 (10%)
Query: 88 ALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERE 147
A G L+EE AR L + Q + RR + + E + RR+ +E E
Sbjct: 1370 AAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEAL 1429
Query: 148 LAEGEEQSEKQERLEQRDRQRRDEEL---------WRQRQEWQEREERR-----AEEEQL 193
E++E +RLE R R+R +EL RQ E+++R+ AEE+
Sbjct: 1430 TQRLAEKTETVDRLE-RGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAA 1488
Query: 194 QSCKGHETEEFPDEEQLRRRELLELRRKGREEKQ-QQRRERQDRVFQEEEEKEWRKRETV 252
E E E + R L L R EE++ ++ ERQ+R + E E ++ V
Sbjct: 1489 VLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDV 1548
Query: 253 LRKEEE-----KLQEEEPQRQR-ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQL 306
+ E ++ E+ R ++ E E++L E +LR E + + Q R Q
Sbjct: 1549 GKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGR 1608
Query: 307 RRKQEEERREQQEERREQQERREQQEERR------EQQLRREQEERREQQLRREQEEERR 360
EE RR+ ++ R+ + R+++ ++R ++L E EE + Q Q +E
Sbjct: 1609 DEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEA 1668
Query: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
+QLR+ Q + + + E + RE+ + ++ + + + LR +++L + R
Sbjct: 1669 VKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRAR 1728
Query: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE-------RRK 473
R+ Q R++ + + + KR+ E R L+ E E E+ E +
Sbjct: 1729 RQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLL 1788
Query: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEER--------------REQRL 519
Q++ E ER + E R+Q ER+ Q+LR E E +L
Sbjct: 1789 LQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKL 1848
Query: 520 KRQEE--EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQ---------RLK 568
+ EE E+ ++R+ S + +RR ++ +E +L+ EEE+R+ + R+Q +LK
Sbjct: 1849 AQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLK 1908
Query: 569 REQEERRDQLLKREEERRQQRLKREQEERLEQ-RLKREEVERLEQEERREQR--LKREEP 625
R+ EE ++ + + RR RL+RE E+ E EV L RR R
Sbjct: 1909 RQLEEAEEEASRAQAGRR--RLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVR 1966
Query: 626 EEERRQQLLKSEEQEERRQ 644
+ R ++ + S+E+ E Q
Sbjct: 1967 QVFRLEEGVASDEEAEEAQ 1985
Score = 113 bits (282), Expect = 2e-24
Identities = 148/573 (25%), Positives = 250/573 (43%), Gaps = 56/573 (9%)
Query: 98 EKRARCDGKESLLQDRRQEEDQRRFE-PRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE 156
EK D E + +QE D + + RQL +++R+ Q E A E
Sbjct: 1435 EKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVE 1494
Query: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELL 216
++ER E R+R L R +E +E R E E+ E E + + +
Sbjct: 1495 ERERAEAEGREREARALSLTRA-LEEEQEAREELERQNRALRAELEALLSSKDDVGKSVH 1553
Query: 217 ELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEE 276
EL R R +Q R E E E E + E +Q + Q +R+LQ +E
Sbjct: 1554 ELERACRVAEQAANDLRAQ---VTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDE 1610
Query: 277 QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE 336
+ R++L ++ ++ E ++ R+++ L ++ + EE + Q Q +E
Sbjct: 1611 AGEE-RRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAV 1669
Query: 337 QQLRREQEERREQQLRREQEEER--REQQLRREQEEERREQQLRREQQLRREQQLRREQQ 394
+QLR+ Q + +E L RE EE R RE+ + +E E+R + L E LR +++L +
Sbjct: 1670 KQLRKMQAQMKE--LWREVEETRTSREEIFSQNRESEKRLKGLEAE-VLRLQEELAASDR 1726
Query: 395 LRREQQLRREQ--------QLRREQQLRREQQLR-REQQLRREQEEERHEQKHEQERREQ 445
RR+ Q R++ L + L ++QL R QL E EEE+ + +R +
Sbjct: 1727 ARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRK 1786
Query: 446 RLKREQE-------ERRDWLKRE---EETERHEQERRKQQLKRDQEEERRERWL------ 489
L + + ER K E ++ ER QE R + + D R +
Sbjct: 1787 LLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALES 1846
Query: 490 KLEEEERREQQERREQQLRREQEERREQRLK----RQEEEERLQQRLRSEQQLRREQEER 545
KL + E + +QE RE+ L + R E+RLK + EEE R+ +LR + + + ++
Sbjct: 1847 KLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQ 1906
Query: 546 REQLLKREEEKRLEQERREQRLKREQEERRD--QLLKREEERRQQRLKR----------E 593
++ L+ EE+ + +RL+RE E+ + + + RE + RL+R
Sbjct: 1907 LKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVR 1966
Query: 594 QEERLEQRLKREEVERLEQEERREQRLKREEPE 626
Q RLE+ + +E E EE + EPE
Sbjct: 1967 QVFRLEEGVASDE----EAEEAQPGSGPSPEPE 1995
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 228 bits (581), Expect = 4e-59
Identities = 316/1226 (25%), Positives = 541/1226 (44%), Gaps = 138/1226 (11%)
Query: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQ----------------QEERREQQERREQ 330
RR Q+ +QQQ LR Q+ + R Q Q+E + + + Q
Sbjct: 820 RRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQ 879
Query: 331 QEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLR 390
+ + +QQ RE E + + + E+E R +QLR E E L E + R +
Sbjct: 880 KVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAE-------LCAEAEETRGRLAA 932
Query: 391 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKRE 450
R+Q+L E ++ E++ R+ Q +++ + QE E H + E R++ +L++
Sbjct: 933 RKQELELVVS-ELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKV 991
Query: 451 QEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRRE 510
E + K EE+ E + K +R E+R + EE + + + +L+ E
Sbjct: 992 TTEAK-MKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYE 1050
Query: 511 -----QEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQ 565
E+R + K ++E E+L++RL E E +EQ++ E+++R E+ R +
Sbjct: 1051 ATIADMEDRLRKEEKGRQELEKLKRRLDG------ESSELQEQMV--EQQQRAEELRAQ- 1101
Query: 566 RLKREQEERRDQLLKREEE--RRQQRLK--REQEERLEQRLKREEVERLEQEERREQRLK 621
L R++EE + L + E+E R Q LK RE + L + + E ER+ + + +QR
Sbjct: 1102 -LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRD 1160
Query: 622 REEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERR 681
E E R + L+ QQ+LR ++++ + K EEE R+ + +E +R
Sbjct: 1161 LGEELEALRGE-LEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQE-LRQRH 1218
Query: 682 EQELAE--EEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKR 739
Q L E E+ EQAR R K K + LE+E ++++ S Q RQE E++R
Sbjct: 1219 GQALGELAEQLEQAR-RGKGAWEKTRLALEAEVSELRAELSSL------QTARQEGEQRR 1271
Query: 740 RRRESELQ-----WQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQR 794
RR E +LQ + ERA + E+ QR QAE ++ G + +R +
Sbjct: 1272 RRLELQLQEVQGRAGDGERARAEAAEKLQRA------QAELENVSGALNEAESKTIRLSK 1325
Query: 795 ERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEED 854
E L + E Q + + L +EE + + R R E + EQL EEE
Sbjct: 1326 E--LSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQL----------EEEA 1373
Query: 855 GLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQ 914
+E R Q + +WR + EEE A+ + Q L E+ E +
Sbjct: 1374 AARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVD 1433
Query: 915 REEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLL 974
R ER +RR Q Q+ ++ + E++++ E++ RK +L +E+ +
Sbjct: 1434 RLERGRRRLQ------------QELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAV 1481
Query: 975 GEEPEKRRRQEREKKYREEEELQ----QEEEQLLREEREKRR---RQEWERQYRKKDELQ 1027
E+R R E E + RE L EEEQ REE E++ R E E KD++
Sbjct: 1482 LRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVG 1541
Query: 1028 QEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQ 1087
+ +L ER R ++ R ++ + E++L E + + R E+ Q K Q
Sbjct: 1542 KSVHEL---ERACRVAEQAANDLR--AQVTELEDELTAAE-DAKLRLEVTVQALK---TQ 1592
Query: 1088 QEEEQLLREEPEKRRRQERERQCREEEELQQEE--EQLLREEREKRRRQELERQYREEEE 1145
E + R+E + RR++ +Q R+ E + EE ++ L K+ ELE +
Sbjct: 1593 HERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMAS 1652
Query: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLRE--EQEKRRQERERQ-YREE 1202
Q +E+ +++ ++ + +++ +RE EE + E++ + E EKR + E + R +
Sbjct: 1653 AGQGKEEAVKQ--LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ 1710
Query: 1203 EEL--QRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQ--- 1257
EEL + R+Q +D D+ +D K A+ + K +GR + +LE+ Q
Sbjct: 1711 EELAASDRARRQAQQDRDEMADEVANGNLSKA-AILEEKRQLEGRLGQLEEELEEEQSNS 1769
Query: 1258 --LRDRQSQQDLQ-----------HLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304
L DR + LQ + E R+Q R+ Q+ EE+ R
Sbjct: 1770 ELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARH 1829
Query: 1305 KE--AKRRDRKSQEEKQLLREEREEKRRRQETDR-KFREEEQLLQEREEQPLRRQERDRK 1361
K A + +Q E+QL +E RE + R + R +E +LQ EE+ + Q RD +
Sbjct: 1830 KMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRD-Q 1888
Query: 1362 FREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ 1421
+ LR ++ R+ E E+ R + R+ L+ E + + E R+ + R
Sbjct: 1889 LEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRG 1948
Query: 1422 QLSRQERD--RKFREEEQQVRRQERE 1445
L+ R + FR EE +E E
Sbjct: 1949 PLTFTTRTVRQVFRLEEGVASDEEAE 1974
Score = 223 bits (568), Expect = 1e-57
Identities = 286/1150 (24%), Positives = 501/1150 (43%), Gaps = 125/1150 (10%)
Query: 130 EEEPGQRRRQKRQE-QERELAEGEEQSEKQERLEQ--RDRQRRDEELWRQRQEWQEREER 186
++E Q R Q+ Q+ QE + E E Q R+ Q +R R E+L + + E EE
Sbjct: 867 QDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEET 926
Query: 187 R----AEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEE 242
R A +++L+ +EE+ R+ E +R QQ +E + + EE
Sbjct: 927 RGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRL-----QQHIQELEAHLEAEEG 981
Query: 243 EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR 302
++ + E V + + K EE+ + + + RKL L + +++++++
Sbjct: 982 ARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKS 1041
Query: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ 362
+LR K E + E+R ++E+ Q+ E+ +++L E E +EQ + ++Q E
Sbjct: 1042 LNKLRLKYEATIADM-EDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRA 1100
Query: 363 QLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 422
QL R++EE + ++ R Q L+ LR Q E Q + L E
Sbjct: 1101 QLGRKEEELQAALARAEDEGGARAQLLK---------SLREAQAALAEAQ----EDLESE 1147
Query: 423 QQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEE 482
+ R + E++R + E E L+ E E+ D ++E R ++E+ +LK+ EE
Sbjct: 1148 RVARTKAEKQRRDLGEELEA----LRGELEDTLDSTNAQQEL-RSKREQEVTELKKTLEE 1202
Query: 483 ERRERWLKLEEEERREQQERRE-----QQLRREQEERREQRLKRQEEEERLQQRLRSEQQ 537
E R ++E +R Q E +Q RR + + RL + E L+ L S Q
Sbjct: 1203 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1262
Query: 538 LRREQEERREQLLKREEE----------KRLEQERREQRLKREQEERRDQLLKREEERRQ 587
R+E E+RR +L + +E R E + QR + E E L E E +
Sbjct: 1263 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGAL--NEAESKT 1320
Query: 588 QRLKREQEERLEQRLKREEVERLEQEERREQ-----RLKREEPEEE-RRQQLLKSEEQEE 641
RL +E Q + + L QEE R + R++ E E R+QL + E
Sbjct: 1321 IRLSKELSSTEAQ---LHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARE 1377
Query: 642 RRQQQLRREQQERREQRLKREEEEERL----EQRLKREHEEERREQELAEEEQ-----EQ 692
R ++L+ Q + E R ++EEE L E R + E E Q LAE+ + E+
Sbjct: 1378 RAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLER 1437
Query: 693 ARERIKSRIP------KWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKR-----RR 741
R R++ + + Q QL S + +Q K +++ R +E +R R
Sbjct: 1438 GRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRE 1497
Query: 742 RESE-------LQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQR 794
RE+ L+ ++E R ++Q R + +++ + L + EQ
Sbjct: 1498 REARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQA 1557
Query: 795 ERQLRAEERQQREQRFLPEEEEKEQR---RRQRREREKELQFLEEEEQLQRRERAQQLQE 851
LRA+ + ++ E+ + + + + E++LQ +E + +RR+ A+QL++
Sbjct: 1558 ANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRD 1617
Query: 852 EEDGLQEDQERR-RSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE-- 908
E ++ D+ER+ R+ +K +LEE + + K +QLRK Q ++E
Sbjct: 1618 AE--VERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELW 1675
Query: 909 ---EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKK 965
EE REE + R+ ++R E ++ + +E+L +R +R+ Q+ + +
Sbjct: 1676 REVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVA 1735
Query: 966 LQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ--------EWE 1017
+ + E EKR+ + R + EE E +Q +LL + K Q E
Sbjct: 1736 NGNLSKAAILE--EKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE 1793
Query: 1018 RQYRKKDE--LQQEEEQL------LREEREKRRLQERERQYREEEELQQEEEQLLGEERE 1069
R + K E QQ E Q+ L EE R + + E +L Q EEQL E RE
Sbjct: 1794 RSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRE 1853
Query: 1070 TRRRQELERQYR---KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE 1126
+L R+ KE LQ EEE+ + ++ + + R + + +L++ EE+ R
Sbjct: 1854 RILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRA 1913
Query: 1127 EREKRRRQELERQYREEEEVQQEEEQLLREEPEKR---RRQELERQYREEEELQQEEEQL 1183
+ +RR Q RE E+V + E + RE R RR L R ++ + EE +
Sbjct: 1914 QAGRRRLQ------RELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGV 1967
Query: 1184 LREEQEKRRQ 1193
+E+ + Q
Sbjct: 1968 ASDEEAEEAQ 1977
Score = 208 bits (529), Expect = 5e-53
Identities = 302/1182 (25%), Positives = 521/1182 (44%), Gaps = 169/1182 (14%)
Query: 843 RERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQ---EQL 899
R Q+ Q+++ L+ Q + + R +W W+L + K LQ ++L
Sbjct: 820 RRAFQKRQQQQSALRVMQRNCAAYLKLRHWQW-WRLFTKVKPLLQVTRQDEVLQARAQEL 878
Query: 900 RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959
+K Q+L Q+ E+ E + R Q +E + R EQL+ E E E + R R+++
Sbjct: 879 QKVQELQQQSAREVG--ELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQE 936
Query: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQ 1019
+ + + E +GEE E R+ + EKK R ++ +Q+ E L EE R++ + E+
Sbjct: 937 L---ELVVSELEARVGEEEECSRQMQTEKK-RLQQHIQELEAHLEAEE-GARQKLQLEKV 991
Query: 1020 YRKKDELQQEEEQLLREEREKRRLQER---ERQYREEEELQQEEEQLLGEERETRRRQE- 1075
+ + EE+ LL E++ + +ER E + E EEE+ + + R + E
Sbjct: 992 TTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEA 1051
Query: 1076 ----LERQYRKEEELQQEEEQLLRE---EPEKRRRQERERQCREEE---ELQQEEEQ--- 1122
+E + RKEE+ +QE E+L R E + + Q E+Q R EE +L ++EE+
Sbjct: 1052 TIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQA 1111
Query: 1123 -LLREEREKRRRQELERQYRE------EEEVQQEEEQLLREEPEKRRR---QELERQYRE 1172
L R E E R +L + RE E + E E++ R + EK+RR +ELE E
Sbjct: 1112 ALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGE 1171
Query: 1173 EEEL--QQEEEQLLREEQEKRRQERERQYREEEEL-QRQKRKQRYRDEDQRSDLKWQWEP 1229
E+ +Q LR ++E+ E ++ EE + + ++ R R +L Q E
Sbjct: 1172 LEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQ 1231
Query: 1230 EK--ENAVRDNKVYCKGRENE---QFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERR 1284
+ + A ++ + +E + L+ ++ Q ++ L+ L E Q R + ER
Sbjct: 1232 ARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERA 1291
Query: 1285 RWQQRDRHFPEEEQLEREE-------------QKEAKRRDRKSQEEKQLLREEREEKRRR 1331
R + ++ + +LE KE + + + ++LL+EE K
Sbjct: 1292 RAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLAL 1351
Query: 1332 QETDRKFREEEQLLQER-EEQPLRRQERDRKFREEELRHQEQGRKFLEE-------EQRL 1383
R E L+E+ EE+ R+ R+ + + + E R+ EE E+
Sbjct: 1352 GSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEAR 1411
Query: 1384 RRQERERKFL------KEEQQLRCQEREQQLRQDRDRKFREEEQQ------LSRQER--D 1429
RR RE + L K E R + ++L+Q+ D + EQQ L +++R D
Sbjct: 1412 RRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFD 1471
Query: 1430 RKFREEEQQVRR--QERER----------------KFLEEEQQLRQERHRKFR----EEE 1467
+ EE+ V R +ERER + LEEEQ+ R+E R+ R E E
Sbjct: 1472 QLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELE 1531
Query: 1468 QLLQEREE--QQLHRQERDRKFLEE-EQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524
LL +++ + +H ER + E+ LR Q + E EL + E + LE Q
Sbjct: 1532 ALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTE---LEDELTAAEDAKLRLEVTVQA 1588
Query: 1525 HRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKF--R 1582
+ Q +R R E G++RR+ ++ R+ E R E +Q+ +K
Sbjct: 1589 LKTQHERDL------QGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGE 1642
Query: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERD 1642
LEE K + + E +QLR+ + Q ++L +E EE + R+E
Sbjct: 1643 LEELKAQMASAGQGKEEAVKQLRKMQAQM-------------KELWREVEETRTSREEIF 1689
Query: 1643 RKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRR 1702
+ E E +L+ E E R +E+L ++ +Q+RD E ++
Sbjct: 1690 SQNRESEKRLKGLEAE---------VLRLQEELAASDRARRQAQQDRD----EMADEVAN 1736
Query: 1703 QERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQ-------- 1754
+ + EE +RQ R + EE+L +E +L +RYRK+L + +
Sbjct: 1737 GNLSKAAILEE---KRQLEGRLGQLEEELEEEQSNSEL-LNDRYRKLLLQVESLTTELSA 1792
Query: 1755 -----LRPEREEQQLRRQERDRKFR--EEEQLRQEREEQQLRSQESDRKFREEEQLRQER 1807
+ E QQL RQ ++ + R EE+ + R + + + ES + + EEQL QE
Sbjct: 1793 ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALES-KLAQAEEQLEQET 1851
Query: 1808 EEQQLRPQ-QRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQ 1866
E+ L + R + R +E LQ+EE+ + Q RD+ + + Q K + EE
Sbjct: 1852 RERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR-VKQLKRQLEE----A 1906
Query: 1867 EEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKG 1908
EEE R Q R+L+ E + E +R+V ++++ +G
Sbjct: 1907 EEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRG 1948
Score = 207 bits (528), Expect = 6e-53
Identities = 274/1193 (22%), Positives = 514/1193 (43%), Gaps = 138/1193 (11%)
Query: 218 LRRKGREEKQQQRR-----ERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE--PQRQRE 270
L R+ +++QQQ+ +R + + +W + T ++ + +++E R +E
Sbjct: 818 LARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQE 877
Query: 271 LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQ 330
LQ+ +E ++ R+ + + + +++R R +QLR E E + EE R + R+Q
Sbjct: 878 LQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRA--EAELCAEAEETRGRLAARKQ 935
Query: 331 QEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLR 390
+ E +L E E + + E++R +Q ++ + E+ R++ QL +
Sbjct: 936 ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEA 995
Query: 391 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKRE 450
+ ++ + L +Q + ++ + + E + +EEE+ + ++ + + +
Sbjct: 996 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1055
Query: 451 QEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQ---QL 507
E+R R+EE R E E+ K++L + E +E+ EQQ+R E+ QL
Sbjct: 1056 MEDR----LRKEEKGRQELEKLKRRLDGESSE---------LQEQMVEQQQRAEELRAQL 1102
Query: 508 RREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL 567
R++EE + + ++E Q L+S ++ + E +E L+ E R + E++ + L
Sbjct: 1103 GRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQED-LESERVARTKAEKQRRDL 1161
Query: 568 KREQEERRDQL---LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE 624
E E R +L L +++ R KREQE E+++ +EE R +E
Sbjct: 1162 GEELEALRGELEDTLDSTNAQQELRSKREQEV--------TELKKTLEEETRIHEAAVQE 1213
Query: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE 684
+ Q L + EQ E Q RR + + RL E E L L +
Sbjct: 1214 LRQRHGQALGELAEQLE----QARRGKGAWEKTRLALEAEVSELRAELS--------SLQ 1261
Query: 685 LAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES 744
A +E EQ R R++ ++ + Q R +G+R R E EK +R ++
Sbjct: 1262 TARQEGEQRRRRLELQLQEVQ-----------------GRAGDGERARAEAAEKLQRAQA 1304
Query: 745 ELQ------WQEEERAHRQQQE----EEQRRDFTWQWQAEEKSE-----RGRQRLSARPP 789
EL+ + E + R +E E Q D Q E +++ R R +
Sbjct: 1305 ELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAG 1364
Query: 790 LREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRER---- 845
LREQ E + A ER RE + + Q RR +E+E LE E+ +RR
Sbjct: 1365 LREQLEEEAAARERAGREL-----QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAE 1419
Query: 846 --AQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQ 903
Q+L E+ + + + RR +Q D LE++R+ L+++ RK
Sbjct: 1420 ALTQRLAEKTETVDRLERGRRRLQQELDDA-TMDLEQQRQ-------LVSTLEKKQRKFD 1471
Query: 904 QLLQEEEEELQR--EEREKRRRQEQERQ------YREEEQLQQEEEQLLREEREKRRRQE 955
QLL EE+ + R EERE+ + +ER+ R E+ Q+ E+L R+ R R E
Sbjct: 1472 QLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELE 1531
Query: 956 RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR---------- 1005
+ D E + E+ R + E+EL E+ LR
Sbjct: 1532 ALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKT 1591
Query: 1006 -EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLL 1064
ER+ + R E + R++ Q + ++ R+E K+R + + E EL++ + Q+
Sbjct: 1592 QHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMA 1651
Query: 1065 ----GEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEE 1120
G+E ++ ++++ Q KE + EE + REE + R+ +R E E+ + +
Sbjct: 1652 SAGQGKEEAVKQLRKMQAQ-MKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ 1710
Query: 1121 EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE 1180
E+L +R +R+ Q+ + +E + + E EKR+ + Q EE E +Q
Sbjct: 1711 EELAASDRARRQAQQDRDEMADEVANGNLSKAAILE--EKRQLEGRLGQLEEELEEEQSN 1768
Query: 1181 EQLLREEQEKRRQERERQYRE---EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRD 1237
+LL + K + E E E + R + E Q +L+ + E A
Sbjct: 1769 SELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARAR 1828
Query: 1238 NKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEE 1297
+K+ E++ +Q ++ Q+ + +L + R E +R ++ EE
Sbjct: 1829 HKMTIAALESKL------AQAEEQLEQETRERILSGKLVRRAE---KRLKEVVLQVEEER 1879
Query: 1298 QLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE 1350
++ + + + ++ + + ++ K+ L E EE R Q R+ + E + + E E
Sbjct: 1880 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAE 1932
Score = 207 bits (526), Expect = 1e-52
Identities = 266/1037 (25%), Positives = 461/1037 (44%), Gaps = 90/1037 (8%)
Query: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154
L+ E+ AR ++ L+ E ++FE D L E+ + ++R+ E LAE Q
Sbjct: 976 LEAEEGAR---QKLQLEKVTTEAKMKKFE-EDLLLLEDQNSKLSKERKLLEDRLAEFSSQ 1031
Query: 155 S-EKQERLEQRDRQRRDEE--LWRQRQEWQEREERRAEEEQLQSCKGHETEEFPD---EE 208
+ E++E+++ ++ R E + ++ E+ R E E+L+ E+ E + E+
Sbjct: 1032 AAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQ 1091
Query: 209 QLRRREL-LELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR 267
Q R EL +L RK E + R + + + K R+ + L + +E L+ E R
Sbjct: 1092 QQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVAR 1151
Query: 268 QRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ---EERREQ 324
+ E+Q R L +EL R E E +Q+LR K+E+E E + EE
Sbjct: 1152 TK----AEKQRRDL-GEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI 1206
Query: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
E Q+ +R Q E E+ EQ R + E+ L E E R E L Q R
Sbjct: 1207 HEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAE--LSSLQTAR 1264
Query: 385 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE 444
+E + RR R E QL+ Q + + R + + Q+ + E E +E E +
Sbjct: 1265 QEGEQRRR---RLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENV-SGALNEAESKT 1320
Query: 445 QRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERRE 504
RL +E L +E + E + R + E L+ + EE +ER
Sbjct: 1321 IRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAG 1380
Query: 505 QQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERRE 564
++L+ Q + E R +RQEEE L + ++ RR E L +R EK +R E
Sbjct: 1381 RELQTAQAQLSEWR-RRQEEE---AGALEAGEEARRRAAREAEALTQRLAEKTETVDRLE 1436
Query: 565 QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE 624
+ +R Q+E D + E++R+ +++ + +Q L E+ L E RE+
Sbjct: 1437 RGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGR 1496
Query: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE 684
E R L ++ E+E+ +++L R+ R R E E L K + + E E
Sbjct: 1497 EREARALSLTRALEEEQEAREEL------ERQNRALRAELEALLSS--KDDVGKSVHELE 1548
Query: 685 LAEEEQEQARERIKSRIPKWQWQLESEADAR-----QSKVYSRPRKQEGQRRRQEQEEKR 739
A EQA +++++ + + +L + DA+ + +++ Q R + EE+R
Sbjct: 1549 RACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERR 1608
Query: 740 RRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPL----REQRE 795
R+ +L+ E ER +E+R+ T A +K E + L A+ +E+
Sbjct: 1609 RQLAKQLRDAEVER-------DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAV 1661
Query: 796 RQLRAEERQQREQRFLPEE--EEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
+QLR + Q +E EE +E+ Q RE EK L+ LE A+ L+ +E
Sbjct: 1662 KQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE----------AEVLRLQE 1711
Query: 854 DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEEL 913
+ D+ RR++Q+ R +E + +K A+ E+ R+ + L + EEEL
Sbjct: 1712 ELAASDRARRQAQQDR---------DEMADEVANGNLSKAAILEEKRQLEGRLGQLEEEL 1762
Query: 914 QREEREKRRRQEQERQ-YREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQ 972
+ E+ ++ R+ + E L E L ER + E RQ + ++++Q+ +
Sbjct: 1763 EEEQSNSELLNDRYRKLLLQVESLTTE----LSAERSFSAKAESGRQ-QLERQIQELRGR 1817
Query: 973 LLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQ 1032
LGEE R + + E +L Q EEQL +E RE+ + R+ K+ ++
Sbjct: 1818 -LGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKR------LKE 1870
Query: 1033 LLREEREKRRLQERERQYREEEEL--QQEEEQLLGEERETRRRQELERQYRKE-EELQQE 1089
++ + E+RR+ ++ R E+ L +Q + QL E E R Q R+ ++E E++ +
Sbjct: 1871 VVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTES 1930
Query: 1090 EEQLLREEPEKRRRQER 1106
E + RE R R R
Sbjct: 1931 AESMNREVTTLRNRLRR 1947
Score = 126 bits (316), Expect = 2e-28
Identities = 153/619 (24%), Positives = 269/619 (43%), Gaps = 65/619 (10%)
Query: 88 ALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERE 147
A G L+EE AR L + Q + RR + + E + RR+ +E E
Sbjct: 1362 AAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEAL 1421
Query: 148 LAEGEEQSEKQERLEQRDRQRRDEEL---------WRQRQEWQEREERR-----AEEEQL 193
E++E +RLE R R+R +EL RQ E+++R+ AEE+
Sbjct: 1422 TQRLAEKTETVDRLE-RGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAA 1480
Query: 194 QSCKGHETEEFPDEEQLRRRELLELRRKGREEKQ-QQRRERQDRVFQEEEEKEWRKRETV 252
E E E + R L L R EE++ ++ ERQ+R + E E ++ V
Sbjct: 1481 VLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDV 1540
Query: 253 LRKEEE-----KLQEEEPQRQR-ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQL 306
+ E ++ E+ R ++ E E++L E +LR E + + Q R Q
Sbjct: 1541 GKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGR 1600
Query: 307 RRKQEEERREQQEERREQQERREQQEERR------EQQLRREQEERREQQLRREQEEERR 360
EE RR+ ++ R+ + R+++ ++R ++L E EE + Q Q +E
Sbjct: 1601 DEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEA 1660
Query: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
+QLR+ Q + + + E + RE+ + ++ + + + LR +++L + R
Sbjct: 1661 VKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRAR 1720
Query: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE-------RRK 473
R+ Q R++ + + + KR+ E R L+ E E E+ E +
Sbjct: 1721 RQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLL 1780
Query: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEER--------------REQRL 519
Q++ E ER + E R+Q ER+ Q+LR E E +L
Sbjct: 1781 LQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKL 1840
Query: 520 KRQEE--EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQ---------RLK 568
+ EE E+ ++R+ S + +RR ++ +E +L+ EEE+R+ + R+Q +LK
Sbjct: 1841 AQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLK 1900
Query: 569 REQEERRDQLLKREEERRQQRLKREQEERLEQ-RLKREEVERLEQEERREQR--LKREEP 625
R+ EE ++ + + RR RL+RE E+ E EV L RR R
Sbjct: 1901 RQLEEAEEEASRAQAGRR--RLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVR 1958
Query: 626 EEERRQQLLKSEEQEERRQ 644
+ R ++ + S+E+ E Q
Sbjct: 1959 QVFRLEEGVASDEEAEEAQ 1977
Score = 113 bits (282), Expect = 2e-24
Identities = 148/573 (25%), Positives = 250/573 (43%), Gaps = 56/573 (9%)
Query: 98 EKRARCDGKESLLQDRRQEEDQRRFE-PRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE 156
EK D E + +QE D + + RQL +++R+ Q E A E
Sbjct: 1427 EKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVE 1486
Query: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELL 216
++ER E R+R L R +E +E R E E+ E E + + +
Sbjct: 1487 ERERAEAEGREREARALSLTRA-LEEEQEAREELERQNRALRAELEALLSSKDDVGKSVH 1545
Query: 217 ELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEE 276
EL R R +Q R E E E E + E +Q + Q +R+LQ +E
Sbjct: 1546 ELERACRVAEQAANDLRAQ---VTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDE 1602
Query: 277 QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE 336
+ R++L ++ ++ E ++ R+++ L ++ + EE + Q Q +E
Sbjct: 1603 AGEE-RRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAV 1661
Query: 337 QQLRREQEERREQQLRREQEEER--REQQLRREQEEERREQQLRREQQLRREQQLRREQQ 394
+QLR+ Q + +E L RE EE R RE+ + +E E+R + L E LR +++L +
Sbjct: 1662 KQLRKMQAQMKE--LWREVEETRTSREEIFSQNRESEKRLKGLEAE-VLRLQEELAASDR 1718
Query: 395 LRREQQLRREQ--------QLRREQQLRREQQLR-REQQLRREQEEERHEQKHEQERREQ 445
RR+ Q R++ L + L ++QL R QL E EEE+ + +R +
Sbjct: 1719 ARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRK 1778
Query: 446 RLKREQE-------ERRDWLKRE---EETERHEQERRKQQLKRDQEEERRERWL------ 489
L + + ER K E ++ ER QE R + + D R +
Sbjct: 1779 LLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALES 1838
Query: 490 KLEEEERREQQERREQQLRREQEERREQRLK----RQEEEERLQQRLRSEQQLRREQEER 545
KL + E + +QE RE+ L + R E+RLK + EEE R+ +LR + + + ++
Sbjct: 1839 KLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQ 1898
Query: 546 REQLLKREEEKRLEQERREQRLKREQEERRD--QLLKREEERRQQRLKR----------E 593
++ L+ EE+ + +RL+RE E+ + + + RE + RL+R
Sbjct: 1899 LKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVR 1958
Query: 594 QEERLEQRLKREEVERLEQEERREQRLKREEPE 626
Q RLE+ + +E E EE + EPE
Sbjct: 1959 QVFRLEEGVASDE----EAEEAQPGSGPSPEPE 1987
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 228 bits (581), Expect = 4e-59
Identities = 316/1226 (25%), Positives = 541/1226 (44%), Gaps = 138/1226 (11%)
Query: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQ----------------QEERREQQERREQ 330
RR Q+ +QQQ LR Q+ + R Q Q+E + + + Q
Sbjct: 861 RRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQ 920
Query: 331 QEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLR 390
+ + +QQ RE E + + + E+E R +QLR E E L E + R +
Sbjct: 921 KVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAE-------LCAEAEETRGRLAA 973
Query: 391 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKRE 450
R+Q+L E ++ E++ R+ Q +++ + QE E H + E R++ +L++
Sbjct: 974 RKQELELVVS-ELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKV 1032
Query: 451 QEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRRE 510
E + K EE+ E + K +R E+R + EE + + + +L+ E
Sbjct: 1033 TTEAK-MKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYE 1091
Query: 511 -----QEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQ 565
E+R + K ++E E+L++RL E E +EQ++ E+++R E+ R +
Sbjct: 1092 ATIADMEDRLRKEEKGRQELEKLKRRLDG------ESSELQEQMV--EQQQRAEELRAQ- 1142
Query: 566 RLKREQEERRDQLLKREEE--RRQQRLK--REQEERLEQRLKREEVERLEQEERREQRLK 621
L R++EE + L + E+E R Q LK RE + L + + E ER+ + + +QR
Sbjct: 1143 -LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRD 1201
Query: 622 REEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERR 681
E E R + L+ QQ+LR ++++ + K EEE R+ + +E +R
Sbjct: 1202 LGEELEALRGE-LEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQE-LRQRH 1259
Query: 682 EQELAE--EEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKR 739
Q L E E+ EQAR R K K + LE+E ++++ S Q RQE E++R
Sbjct: 1260 GQALGELAEQLEQAR-RGKGAWEKTRLALEAEVSELRAELSSL------QTARQEGEQRR 1312
Query: 740 RRRESELQ-----WQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQR 794
RR E +LQ + ERA + E+ QR QAE ++ G + +R +
Sbjct: 1313 RRLELQLQEVQGRAGDGERARAEAAEKLQRA------QAELENVSGALNEAESKTIRLSK 1366
Query: 795 ERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEED 854
E L + E Q + + L +EE + + R R E + EQL EEE
Sbjct: 1367 E--LSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQL----------EEEA 1414
Query: 855 GLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQ 914
+E R Q + +WR + EEE A+ + Q L E+ E +
Sbjct: 1415 AARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVD 1474
Query: 915 REEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLL 974
R ER +RR Q Q+ ++ + E++++ E++ RK +L +E+ +
Sbjct: 1475 RLERGRRRLQ------------QELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAV 1522
Query: 975 GEEPEKRRRQEREKKYREEEELQ----QEEEQLLREEREKRR---RQEWERQYRKKDELQ 1027
E+R R E E + RE L EEEQ REE E++ R E E KD++
Sbjct: 1523 LRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVG 1582
Query: 1028 QEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQ 1087
+ +L ER R ++ R ++ + E++L E + + R E+ Q K Q
Sbjct: 1583 KSVHEL---ERACRVAEQAANDLR--AQVTELEDELTAAE-DAKLRLEVTVQALK---TQ 1633
Query: 1088 QEEEQLLREEPEKRRRQERERQCREEEELQQEE--EQLLREEREKRRRQELERQYREEEE 1145
E + R+E + RR++ +Q R+ E + EE ++ L K+ ELE +
Sbjct: 1634 HERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMAS 1693
Query: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLRE--EQEKRRQERERQ-YREE 1202
Q +E+ +++ ++ + +++ +RE EE + E++ + E EKR + E + R +
Sbjct: 1694 AGQGKEEAVKQ--LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ 1751
Query: 1203 EEL--QRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQ--- 1257
EEL + R+Q +D D+ +D K A+ + K +GR + +LE+ Q
Sbjct: 1752 EELAASDRARRQAQQDRDEMADEVANGNLSKA-AILEEKRQLEGRLGQLEEELEEEQSNS 1810
Query: 1258 --LRDRQSQQDLQ-----------HLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304
L DR + LQ + E R+Q R+ Q+ EE+ R
Sbjct: 1811 ELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARH 1870
Query: 1305 KE--AKRRDRKSQEEKQLLREEREEKRRRQETDR-KFREEEQLLQEREEQPLRRQERDRK 1361
K A + +Q E+QL +E RE + R + R +E +LQ EE+ + Q RD +
Sbjct: 1871 KMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRD-Q 1929
Query: 1362 FREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ 1421
+ LR ++ R+ E E+ R + R+ L+ E + + E R+ + R
Sbjct: 1930 LEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRG 1989
Query: 1422 QLSRQERD--RKFREEEQQVRRQERE 1445
L+ R + FR EE +E E
Sbjct: 1990 PLTFTTRTVRQVFRLEEGVASDEEAE 2015
Score = 223 bits (568), Expect = 1e-57
Identities = 286/1150 (24%), Positives = 501/1150 (43%), Gaps = 125/1150 (10%)
Query: 130 EEEPGQRRRQKRQE-QERELAEGEEQSEKQERLEQ--RDRQRRDEELWRQRQEWQEREER 186
++E Q R Q+ Q+ QE + E E Q R+ Q +R R E+L + + E EE
Sbjct: 908 QDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEET 967
Query: 187 R----AEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEE 242
R A +++L+ +EE+ R+ E +R QQ +E + + EE
Sbjct: 968 RGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRL-----QQHIQELEAHLEAEEG 1022
Query: 243 EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR 302
++ + E V + + K EE+ + + + RKL L + +++++++
Sbjct: 1023 ARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKS 1082
Query: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ 362
+LR K E + E+R ++E+ Q+ E+ +++L E E +EQ + ++Q E
Sbjct: 1083 LNKLRLKYEATIADM-EDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRA 1141
Query: 363 QLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 422
QL R++EE + ++ R Q L+ LR Q E Q + L E
Sbjct: 1142 QLGRKEEELQAALARAEDEGGARAQLLK---------SLREAQAALAEAQ----EDLESE 1188
Query: 423 QQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEE 482
+ R + E++R + E E L+ E E+ D ++E R ++E+ +LK+ EE
Sbjct: 1189 RVARTKAEKQRRDLGEELEA----LRGELEDTLDSTNAQQEL-RSKREQEVTELKKTLEE 1243
Query: 483 ERRERWLKLEEEERREQQERRE-----QQLRREQEERREQRLKRQEEEERLQQRLRSEQQ 537
E R ++E +R Q E +Q RR + + RL + E L+ L S Q
Sbjct: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303
Query: 538 LRREQEERREQLLKREEE----------KRLEQERREQRLKREQEERRDQLLKREEERRQ 587
R+E E+RR +L + +E R E + QR + E E L E E +
Sbjct: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGAL--NEAESKT 1361
Query: 588 QRLKREQEERLEQRLKREEVERLEQEERREQ-----RLKREEPEEE-RRQQLLKSEEQEE 641
RL +E Q + + L QEE R + R++ E E R+QL + E
Sbjct: 1362 IRLSKELSSTEAQ---LHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARE 1418
Query: 642 RRQQQLRREQQERREQRLKREEEEERL----EQRLKREHEEERREQELAEEEQ-----EQ 692
R ++L+ Q + E R ++EEE L E R + E E Q LAE+ + E+
Sbjct: 1419 RAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLER 1478
Query: 693 ARERIKSRIP------KWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKR-----RR 741
R R++ + + Q QL S + +Q K +++ R +E +R R
Sbjct: 1479 GRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRE 1538
Query: 742 RESE-------LQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQR 794
RE+ L+ ++E R ++Q R + +++ + L + EQ
Sbjct: 1539 REARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQA 1598
Query: 795 ERQLRAEERQQREQRFLPEEEEKEQR---RRQRREREKELQFLEEEEQLQRRERAQQLQE 851
LRA+ + ++ E+ + + + + E++LQ +E + +RR+ A+QL++
Sbjct: 1599 ANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRD 1658
Query: 852 EEDGLQEDQERR-RSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE-- 908
E ++ D+ER+ R+ +K +LEE + + K +QLRK Q ++E
Sbjct: 1659 AE--VERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELW 1716
Query: 909 ---EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKK 965
EE REE + R+ ++R E ++ + +E+L +R +R+ Q+ + +
Sbjct: 1717 REVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVA 1776
Query: 966 LQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ--------EWE 1017
+ + E EKR+ + R + EE E +Q +LL + K Q E
Sbjct: 1777 NGNLSKAAILE--EKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE 1834
Query: 1018 RQYRKKDE--LQQEEEQL------LREEREKRRLQERERQYREEEELQQEEEQLLGEERE 1069
R + K E QQ E Q+ L EE R + + E +L Q EEQL E RE
Sbjct: 1835 RSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRE 1894
Query: 1070 TRRRQELERQYR---KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE 1126
+L R+ KE LQ EEE+ + ++ + + R + + +L++ EE+ R
Sbjct: 1895 RILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRA 1954
Query: 1127 EREKRRRQELERQYREEEEVQQEEEQLLREEPEKR---RRQELERQYREEEELQQEEEQL 1183
+ +RR Q RE E+V + E + RE R RR L R ++ + EE +
Sbjct: 1955 QAGRRRLQ------RELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGV 2008
Query: 1184 LREEQEKRRQ 1193
+E+ + Q
Sbjct: 2009 ASDEEAEEAQ 2018
Score = 208 bits (529), Expect = 5e-53
Identities = 302/1182 (25%), Positives = 521/1182 (44%), Gaps = 169/1182 (14%)
Query: 843 RERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQ---EQL 899
R Q+ Q+++ L+ Q + + R +W W+L + K LQ ++L
Sbjct: 861 RRAFQKRQQQQSALRVMQRNCAAYLKLRHWQW-WRLFTKVKPLLQVTRQDEVLQARAQEL 919
Query: 900 RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959
+K Q+L Q+ E+ E + R Q +E + R EQL+ E E E + R R+++
Sbjct: 920 QKVQELQQQSAREVG--ELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQE 977
Query: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQ 1019
+ + + E +GEE E R+ + EKK R ++ +Q+ E L EE R++ + E+
Sbjct: 978 L---ELVVSELEARVGEEEECSRQMQTEKK-RLQQHIQELEAHLEAEE-GARQKLQLEKV 1032
Query: 1020 YRKKDELQQEEEQLLREEREKRRLQER---ERQYREEEELQQEEEQLLGEERETRRRQE- 1075
+ + EE+ LL E++ + +ER E + E EEE+ + + R + E
Sbjct: 1033 TTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEA 1092
Query: 1076 ----LERQYRKEEELQQEEEQLLRE---EPEKRRRQERERQCREEE---ELQQEEEQ--- 1122
+E + RKEE+ +QE E+L R E + + Q E+Q R EE +L ++EE+
Sbjct: 1093 TIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQA 1152
Query: 1123 -LLREEREKRRRQELERQYRE------EEEVQQEEEQLLREEPEKRRR---QELERQYRE 1172
L R E E R +L + RE E + E E++ R + EK+RR +ELE E
Sbjct: 1153 ALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGE 1212
Query: 1173 EEEL--QQEEEQLLREEQEKRRQERERQYREEEEL-QRQKRKQRYRDEDQRSDLKWQWEP 1229
E+ +Q LR ++E+ E ++ EE + + ++ R R +L Q E
Sbjct: 1213 LEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQ 1272
Query: 1230 EK--ENAVRDNKVYCKGRENE---QFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERR 1284
+ + A ++ + +E + L+ ++ Q ++ L+ L E Q R + ER
Sbjct: 1273 ARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERA 1332
Query: 1285 RWQQRDRHFPEEEQLEREE-------------QKEAKRRDRKSQEEKQLLREEREEKRRR 1331
R + ++ + +LE KE + + + ++LL+EE K
Sbjct: 1333 RAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLAL 1392
Query: 1332 QETDRKFREEEQLLQER-EEQPLRRQERDRKFREEELRHQEQGRKFLEE-------EQRL 1383
R E L+E+ EE+ R+ R+ + + + E R+ EE E+
Sbjct: 1393 GSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEAR 1452
Query: 1384 RRQERERKFL------KEEQQLRCQEREQQLRQDRDRKFREEEQQ------LSRQER--D 1429
RR RE + L K E R + ++L+Q+ D + EQQ L +++R D
Sbjct: 1453 RRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFD 1512
Query: 1430 RKFREEEQQVRR--QERER----------------KFLEEEQQLRQERHRKFR----EEE 1467
+ EE+ V R +ERER + LEEEQ+ R+E R+ R E E
Sbjct: 1513 QLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELE 1572
Query: 1468 QLLQEREE--QQLHRQERDRKFLEE-EQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524
LL +++ + +H ER + E+ LR Q + E EL + E + LE Q
Sbjct: 1573 ALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTE---LEDELTAAEDAKLRLEVTVQA 1629
Query: 1525 HRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKF--R 1582
+ Q +R R E G++RR+ ++ R+ E R E +Q+ +K
Sbjct: 1630 LKTQHERDL------QGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGE 1683
Query: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERD 1642
LEE K + + E +QLR+ + Q ++L +E EE + R+E
Sbjct: 1684 LEELKAQMASAGQGKEEAVKQLRKMQAQM-------------KELWREVEETRTSREEIF 1730
Query: 1643 RKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRR 1702
+ E E +L+ E E R +E+L ++ +Q+RD E ++
Sbjct: 1731 SQNRESEKRLKGLEAE---------VLRLQEELAASDRARRQAQQDRD----EMADEVAN 1777
Query: 1703 QERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQ-------- 1754
+ + EE +RQ R + EE+L +E +L +RYRK+L + +
Sbjct: 1778 GNLSKAAILEE---KRQLEGRLGQLEEELEEEQSNSEL-LNDRYRKLLLQVESLTTELSA 1833
Query: 1755 -----LRPEREEQQLRRQERDRKFR--EEEQLRQEREEQQLRSQESDRKFREEEQLRQER 1807
+ E QQL RQ ++ + R EE+ + R + + + ES + + EEQL QE
Sbjct: 1834 ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALES-KLAQAEEQLEQET 1892
Query: 1808 EEQQLRPQ-QRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQ 1866
E+ L + R + R +E LQ+EE+ + Q RD+ + + Q K + EE
Sbjct: 1893 RERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR-VKQLKRQLEE----A 1947
Query: 1867 EEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKG 1908
EEE R Q R+L+ E + E +R+V ++++ +G
Sbjct: 1948 EEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRG 1989
Score = 207 bits (528), Expect = 6e-53
Identities = 274/1193 (22%), Positives = 514/1193 (43%), Gaps = 138/1193 (11%)
Query: 218 LRRKGREEKQQQRR-----ERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE--PQRQRE 270
L R+ +++QQQ+ +R + + +W + T ++ + +++E R +E
Sbjct: 859 LARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQE 918
Query: 271 LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQ 330
LQ+ +E ++ R+ + + + +++R R +QLR E E + EE R + R+Q
Sbjct: 919 LQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRA--EAELCAEAEETRGRLAARKQ 976
Query: 331 QEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLR 390
+ E +L E E + + E++R +Q ++ + E+ R++ QL +
Sbjct: 977 ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEA 1036
Query: 391 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKRE 450
+ ++ + L +Q + ++ + + E + +EEE+ + ++ + + +
Sbjct: 1037 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1096
Query: 451 QEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQ---QL 507
E+R R+EE R E E+ K++L + E +E+ EQQ+R E+ QL
Sbjct: 1097 MEDR----LRKEEKGRQELEKLKRRLDGESSE---------LQEQMVEQQQRAEELRAQL 1143
Query: 508 RREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL 567
R++EE + + ++E Q L+S ++ + E +E L+ E R + E++ + L
Sbjct: 1144 GRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQED-LESERVARTKAEKQRRDL 1202
Query: 568 KREQEERRDQL---LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE 624
E E R +L L +++ R KREQE E+++ +EE R +E
Sbjct: 1203 GEELEALRGELEDTLDSTNAQQELRSKREQEV--------TELKKTLEEETRIHEAAVQE 1254
Query: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE 684
+ Q L + EQ E Q RR + + RL E E L L +
Sbjct: 1255 LRQRHGQALGELAEQLE----QARRGKGAWEKTRLALEAEVSELRAELS--------SLQ 1302
Query: 685 LAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES 744
A +E EQ R R++ ++ + Q R +G+R R E EK +R ++
Sbjct: 1303 TARQEGEQRRRRLELQLQEVQ-----------------GRAGDGERARAEAAEKLQRAQA 1345
Query: 745 ELQ------WQEEERAHRQQQE----EEQRRDFTWQWQAEEKSE-----RGRQRLSARPP 789
EL+ + E + R +E E Q D Q E +++ R R +
Sbjct: 1346 ELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAG 1405
Query: 790 LREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRER---- 845
LREQ E + A ER RE + + Q RR +E+E LE E+ +RR
Sbjct: 1406 LREQLEEEAAARERAGREL-----QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAE 1460
Query: 846 --AQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQ 903
Q+L E+ + + + RR +Q D LE++R+ L+++ RK
Sbjct: 1461 ALTQRLAEKTETVDRLERGRRRLQQELDDA-TMDLEQQRQ-------LVSTLEKKQRKFD 1512
Query: 904 QLLQEEEEELQR--EEREKRRRQEQERQ------YREEEQLQQEEEQLLREEREKRRRQE 955
QLL EE+ + R EERE+ + +ER+ R E+ Q+ E+L R+ R R E
Sbjct: 1513 QLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELE 1572
Query: 956 RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR---------- 1005
+ D E + E+ R + E+EL E+ LR
Sbjct: 1573 ALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKT 1632
Query: 1006 -EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLL 1064
ER+ + R E + R++ Q + ++ R+E K+R + + E EL++ + Q+
Sbjct: 1633 QHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMA 1692
Query: 1065 ----GEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEE 1120
G+E ++ ++++ Q KE + EE + REE + R+ +R E E+ + +
Sbjct: 1693 SAGQGKEEAVKQLRKMQAQ-MKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ 1751
Query: 1121 EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE 1180
E+L +R +R+ Q+ + +E + + E EKR+ + Q EE E +Q
Sbjct: 1752 EELAASDRARRQAQQDRDEMADEVANGNLSKAAILE--EKRQLEGRLGQLEEELEEEQSN 1809
Query: 1181 EQLLREEQEKRRQERERQYRE---EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRD 1237
+LL + K + E E E + R + E Q +L+ + E A
Sbjct: 1810 SELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARAR 1869
Query: 1238 NKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEE 1297
+K+ E++ +Q ++ Q+ + +L + R E +R ++ EE
Sbjct: 1870 HKMTIAALESKL------AQAEEQLEQETRERILSGKLVRRAE---KRLKEVVLQVEEER 1920
Query: 1298 QLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE 1350
++ + + + ++ + + ++ K+ L E EE R Q R+ + E + + E E
Sbjct: 1921 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAE 1973
Score = 207 bits (526), Expect = 1e-52
Identities = 266/1037 (25%), Positives = 461/1037 (44%), Gaps = 90/1037 (8%)
Query: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154
L+ E+ AR ++ L+ E ++FE D L E+ + ++R+ E LAE Q
Sbjct: 1017 LEAEEGAR---QKLQLEKVTTEAKMKKFE-EDLLLLEDQNSKLSKERKLLEDRLAEFSSQ 1072
Query: 155 S-EKQERLEQRDRQRRDEE--LWRQRQEWQEREERRAEEEQLQSCKGHETEEFPD---EE 208
+ E++E+++ ++ R E + ++ E+ R E E+L+ E+ E + E+
Sbjct: 1073 AAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQ 1132
Query: 209 QLRRREL-LELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR 267
Q R EL +L RK E + R + + + K R+ + L + +E L+ E R
Sbjct: 1133 QQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVAR 1192
Query: 268 QRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ---EERREQ 324
+ E+Q R L +EL R E E +Q+LR K+E+E E + EE
Sbjct: 1193 TK----AEKQRRDL-GEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI 1247
Query: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
E Q+ +R Q E E+ EQ R + E+ L E E R E L Q R
Sbjct: 1248 HEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAE--LSSLQTAR 1305
Query: 385 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE 444
+E + RR R E QL+ Q + + R + + Q+ + E E +E E +
Sbjct: 1306 QEGEQRRR---RLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENV-SGALNEAESKT 1361
Query: 445 QRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERRE 504
RL +E L +E + E + R + E L+ + EE +ER
Sbjct: 1362 IRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAG 1421
Query: 505 QQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERRE 564
++L+ Q + E R +RQEEE L + ++ RR E L +R EK +R E
Sbjct: 1422 RELQTAQAQLSEWR-RRQEEE---AGALEAGEEARRRAAREAEALTQRLAEKTETVDRLE 1477
Query: 565 QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE 624
+ +R Q+E D + E++R+ +++ + +Q L E+ L E RE+
Sbjct: 1478 RGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGR 1537
Query: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE 684
E R L ++ E+E+ +++L R+ R R E E L K + + E E
Sbjct: 1538 EREARALSLTRALEEEQEAREEL------ERQNRALRAELEALLSS--KDDVGKSVHELE 1589
Query: 685 LAEEEQEQARERIKSRIPKWQWQLESEADAR-----QSKVYSRPRKQEGQRRRQEQEEKR 739
A EQA +++++ + + +L + DA+ + +++ Q R + EE+R
Sbjct: 1590 RACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERR 1649
Query: 740 RRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPL----REQRE 795
R+ +L+ E ER +E+R+ T A +K E + L A+ +E+
Sbjct: 1650 RQLAKQLRDAEVER-------DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAV 1702
Query: 796 RQLRAEERQQREQRFLPEE--EEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
+QLR + Q +E EE +E+ Q RE EK L+ LE A+ L+ +E
Sbjct: 1703 KQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE----------AEVLRLQE 1752
Query: 854 DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEEL 913
+ D+ RR++Q+ R +E + +K A+ E+ R+ + L + EEEL
Sbjct: 1753 ELAASDRARRQAQQDR---------DEMADEVANGNLSKAAILEEKRQLEGRLGQLEEEL 1803
Query: 914 QREEREKRRRQEQERQ-YREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQ 972
+ E+ ++ R+ + E L E L ER + E RQ + ++++Q+ +
Sbjct: 1804 EEEQSNSELLNDRYRKLLLQVESLTTE----LSAERSFSAKAESGRQ-QLERQIQELRGR 1858
Query: 973 LLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQ 1032
LGEE R + + E +L Q EEQL +E RE+ + R+ K+ ++
Sbjct: 1859 -LGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKR------LKE 1911
Query: 1033 LLREEREKRRLQERERQYREEEEL--QQEEEQLLGEERETRRRQELERQYRKE-EELQQE 1089
++ + E+RR+ ++ R E+ L +Q + QL E E R Q R+ ++E E++ +
Sbjct: 1912 VVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTES 1971
Query: 1090 EEQLLREEPEKRRRQER 1106
E + RE R R R
Sbjct: 1972 AESMNREVTTLRNRLRR 1988
Score = 126 bits (316), Expect = 2e-28
Identities = 153/619 (24%), Positives = 269/619 (43%), Gaps = 65/619 (10%)
Query: 88 ALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERE 147
A G L+EE AR L + Q + RR + + E + RR+ +E E
Sbjct: 1403 AAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEAL 1462
Query: 148 LAEGEEQSEKQERLEQRDRQRRDEEL---------WRQRQEWQEREERR-----AEEEQL 193
E++E +RLE R R+R +EL RQ E+++R+ AEE+
Sbjct: 1463 TQRLAEKTETVDRLE-RGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAA 1521
Query: 194 QSCKGHETEEFPDEEQLRRRELLELRRKGREEKQ-QQRRERQDRVFQEEEEKEWRKRETV 252
E E E + R L L R EE++ ++ ERQ+R + E E ++ V
Sbjct: 1522 VLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDV 1581
Query: 253 LRKEEE-----KLQEEEPQRQR-ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQL 306
+ E ++ E+ R ++ E E++L E +LR E + + Q R Q
Sbjct: 1582 GKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGR 1641
Query: 307 RRKQEEERREQQEERREQQERREQQEERR------EQQLRREQEERREQQLRREQEEERR 360
EE RR+ ++ R+ + R+++ ++R ++L E EE + Q Q +E
Sbjct: 1642 DEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEA 1701
Query: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
+QLR+ Q + + + E + RE+ + ++ + + + LR +++L + R
Sbjct: 1702 VKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRAR 1761
Query: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE-------RRK 473
R+ Q R++ + + + KR+ E R L+ E E E+ E +
Sbjct: 1762 RQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLL 1821
Query: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEER--------------REQRL 519
Q++ E ER + E R+Q ER+ Q+LR E E +L
Sbjct: 1822 LQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKL 1881
Query: 520 KRQEE--EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQ---------RLK 568
+ EE E+ ++R+ S + +RR ++ +E +L+ EEE+R+ + R+Q +LK
Sbjct: 1882 AQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLK 1941
Query: 569 REQEERRDQLLKREEERRQQRLKREQEERLEQ-RLKREEVERLEQEERREQR--LKREEP 625
R+ EE ++ + + RR RL+RE E+ E EV L RR R
Sbjct: 1942 RQLEEAEEEASRAQAGRR--RLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVR 1999
Query: 626 EEERRQQLLKSEEQEERRQ 644
+ R ++ + S+E+ E Q
Sbjct: 2000 QVFRLEEGVASDEEAEEAQ 2018
Score = 113 bits (282), Expect = 2e-24
Identities = 148/573 (25%), Positives = 250/573 (43%), Gaps = 56/573 (9%)
Query: 98 EKRARCDGKESLLQDRRQEEDQRRFE-PRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE 156
EK D E + +QE D + + RQL +++R+ Q E A E
Sbjct: 1468 EKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVE 1527
Query: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELL 216
++ER E R+R L R +E +E R E E+ E E + + +
Sbjct: 1528 ERERAEAEGREREARALSLTRA-LEEEQEAREELERQNRALRAELEALLSSKDDVGKSVH 1586
Query: 217 ELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEE 276
EL R R +Q R E E E E + E +Q + Q +R+LQ +E
Sbjct: 1587 ELERACRVAEQAANDLRAQ---VTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDE 1643
Query: 277 QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE 336
+ R++L ++ ++ E ++ R+++ L ++ + EE + Q Q +E
Sbjct: 1644 AGEE-RRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAV 1702
Query: 337 QQLRREQEERREQQLRREQEEER--REQQLRREQEEERREQQLRREQQLRREQQLRREQQ 394
+QLR+ Q + +E L RE EE R RE+ + +E E+R + L E LR +++L +
Sbjct: 1703 KQLRKMQAQMKE--LWREVEETRTSREEIFSQNRESEKRLKGLEAE-VLRLQEELAASDR 1759
Query: 395 LRREQQLRREQ--------QLRREQQLRREQQLR-REQQLRREQEEERHEQKHEQERREQ 445
RR+ Q R++ L + L ++QL R QL E EEE+ + +R +
Sbjct: 1760 ARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRK 1819
Query: 446 RLKREQE-------ERRDWLKRE---EETERHEQERRKQQLKRDQEEERRERWL------ 489
L + + ER K E ++ ER QE R + + D R +
Sbjct: 1820 LLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALES 1879
Query: 490 KLEEEERREQQERREQQLRREQEERREQRLK----RQEEEERLQQRLRSEQQLRREQEER 545
KL + E + +QE RE+ L + R E+RLK + EEE R+ +LR + + + ++
Sbjct: 1880 KLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQ 1939
Query: 546 REQLLKREEEKRLEQERREQRLKREQEERRD--QLLKREEERRQQRLKR----------E 593
++ L+ EE+ + +RL+RE E+ + + + RE + RL+R
Sbjct: 1940 LKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVR 1999
Query: 594 QEERLEQRLKREEVERLEQEERREQRLKREEPE 626
Q RLE+ + +E E EE + EPE
Sbjct: 2000 QVFRLEEGVASDE----EAEEAQPGSGPSPEPE 2028
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 227 bits (579), Expect = 8e-59
Identities = 402/1979 (20%), Positives = 832/1979 (42%), Gaps = 236/1979 (11%)
Query: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154
L EE + D S +E DQ + ++ + E R + ++ E LAE
Sbjct: 724 LIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTE----LRAQVKQLEMNLAE---- 775
Query: 155 SEKQERLEQRDRQRRDEELWRQRQEWQ-EREERRAEEEQLQSCKGHETEEFPDEEQLRRR 213
+E+Q RL+ + D L Q E + + + E LQ+ +F ++ L R
Sbjct: 776 AERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRS 835
Query: 214 ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQ---RQRE 270
+L+ K E + R R EE + ++E + K ++ L E++ Q+
Sbjct: 836 LQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQT 895
Query: 271 LQEEEEQLRKL------ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
++E+++Q+ ++ + +L E+ + + L+ + L + EE ++EQ EE E
Sbjct: 896 IEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEV 955
Query: 325 QERREQQEERREQ--QLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQ 382
+Q + Q+ +E+ + L++E E+ +R+ Q +E ++ R E++
Sbjct: 956 SSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEE 1015
Query: 383 LRR-----EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQK 437
L ++++ + R E + +E + E+ + + Q E L++ E+ E +
Sbjct: 1016 LANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQ-EIEIYLKQTISEKEVELQ 1074
Query: 438 HEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERR 497
H ++ E++L E E+ + +K+ +T Q++ Q E + ++
Sbjct: 1075 HIRKDLEEKLAAE-EQFQALVKQMNQTL---QDKTNQIDLLQAEISENQAIIQKLITSNT 1130
Query: 498 EQQERREQQLRRE---------------QEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
+ + L +E + E E+ L ++E+E+LQ++L+ E
Sbjct: 1131 DASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQ-------EA 1183
Query: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQ---EERLE 599
R+ +LK+ +EK E+ L+ E ++++D + +E+ +Q + E + R
Sbjct: 1184 LTSRKAILKKAQEK-------ERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQL 1236
Query: 600 QRLKREEVE----RLEQEERREQRLKREEP-----EEERRQQLLKSE-------EQEERR 643
Q RE ++ +Q+E EEP E+ Q +L+S E+
Sbjct: 1237 QIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDAS 1296
Query: 644 QQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARER---IKSR 700
Q + + Q + E E+ LE ++ E ++ E + QEQ ++ I+S
Sbjct: 1297 ALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIES- 1355
Query: 701 IPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQE 760
+ + E A++ Q K+ S + G +E + K + + +EE+ ++ Q
Sbjct: 1356 LKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQL 1415
Query: 761 EEQRRDFTWQW----QAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEE 816
E+ T + E+ + +L + ++R +QL+ E + +++ PEE
Sbjct: 1416 SEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQK---PEEIG 1472
Query: 817 KEQRRRQRREREKELQFLEEEEQLQRRERAQQ--------LQEEEDGLQEDQERRRSQEQ 868
+E R +Q+ +R+ + + +E L+ + Q+ ++ L + + + +Q +
Sbjct: 1473 EESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNK 1532
Query: 869 RRDQKW-RWQLEEERKRRRHTLYAKPALQEQ--------LRKEQQLLQEEEEELQRE-ER 918
+D R L +E + + T + L+ Q L+ + L E++E+L +E E
Sbjct: 1533 EKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIES 1592
Query: 919 EKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEP 978
K + + +++E+ + Q+E ++L + E E ER + ++Q++++L G
Sbjct: 1593 LKSSKIAESTEWQEKHKELQKEYEILLQSYENVSN-EAERIQHVVEAVRQEKQELYG--- 1648
Query: 979 EKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE-- 1036
K R E KK E E+ QE EQ + E +EK R+ +Q +K EL++E ++L E
Sbjct: 1649 -KLRSTEANKK--ETEKQLQEAEQEMEEMKEKMRKFAKSKQ-QKILELEEENDRLRAEVH 1704
Query: 1037 --------------EREKRRLQERERQYREEEELQQEEEQLLGE-----ERETRRRQELE 1077
+E ER E E L ++ + L+ E E + ++E
Sbjct: 1705 PAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIE 1764
Query: 1078 RQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE--REKRRRQE 1135
K+ L+ E+ + + Q + E++ L E K
Sbjct: 1765 GNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPA 1824
Query: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE----LQQEEEQLLREEQEKR 1191
+ + + +E+ +Q+ + K R LE + ++ +E L+ E+ LL + K
Sbjct: 1825 VSKDFSSHDEINNYLQQI---DQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTK- 1880
Query: 1192 RQERERQYREEEELQRQKRKQRYRDEDQR-SDLKWQWEPEK---ENAVRDNKVYCKGREN 1247
+ E + +EE + Q+ ++E R + LK E EK E + + G
Sbjct: 1881 --DGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIG 1938
Query: 1248 EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEA 1307
+ + D+Q+++ + ++++L E + E+++ E+ ++E E +KE
Sbjct: 1939 NYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQL--------VKEKTKVESEIRKEY 1990
Query: 1308 KRRDRKSQEE----------KQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR--- 1354
+ + +Q+E ++LL+E+++E ++ Q+ +++E+ L ER + L
Sbjct: 1991 LEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISAL-ERTVKALEFVQ 2049
Query: 1355 -RQERDRKFREEELRHQEQGRKFLEEE------------QRLRRQERERKFLKEEQQLRC 1401
++D + +E L + RK + E R + LK+E Q
Sbjct: 2050 TESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNK 2109
Query: 1402 QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHR 1461
+ + Q++Q + R EQ + +++K +E+ R RE+ LEE Q
Sbjct: 2110 ESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALR--REKVHLEETIGEIQVTLN 2167
Query: 1462 KFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERD------RKFREQELRSQEPER 1515
K +E Q LQE + + + K + Q R + D RKF + ++S+E E
Sbjct: 2168 KKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDA-IQSKEEEI 2226
Query: 1516 KFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE-------RE 1568
+ E+ + + Q ++ + E+ R + +Q + K + E QL+Q+
Sbjct: 2227 RLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGEN 2286
Query: 1569 EQQLSRQERDRK-FRLEEQKVRRQEQERKFMEDE--------QQLRRQEGQQQLRQERDR 1619
++ LS+ E R + + ++ + E E K ++D+ ++ + Q+G + +
Sbjct: 2287 KELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQE 2346
Query: 1620 KFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQE-------REQ-------QLRHDR 1665
++ + E+ E L L EE ++ Q+ +E+ +LR
Sbjct: 2347 ADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQH 2406
Query: 1666 DRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKF 1725
D++ +E E LL + EE+ + +E ++K ++ QL + K +Q+ + +
Sbjct: 2407 DKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSM 2466
Query: 1726 REEEQLRQETEQEQLRRQERYRK-ILEEEQLRPEREEQQLRRQERDRKFR------EEEQ 1778
+ R + + +ER+ ILE++QL E + + +E R R E
Sbjct: 2467 SSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSEN 2526
Query: 1779 LRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQL-QLEEQEQRL 1837
+ + E Q R + ++ Q +Q E Q + ++ + KY EE+L + EE + L
Sbjct: 2527 AKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDL 2586
Query: 1838 RQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHR 1896
R+ + ++ + + +S + + Q Q + E L H + + KEE+ HR
Sbjct: 2587 RRSFNALQEEKQDLSKEIESLK--VSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHR 2643
Score = 224 bits (572), Expect = 5e-58
Identities = 395/1945 (20%), Positives = 833/1945 (42%), Gaps = 247/1945 (12%)
Query: 152 EEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCK--GHETEEFPDEEQ 209
E ++EK E LE + E + + +Q +E+ + +++S K HE E + Q
Sbjct: 1313 EIEAEKVE-LELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQ 1371
Query: 210 LRRRELLELRRKGRE---EKQQQRRERQDRVFQEEEEKEW-----RKRETVLRKEEEKLQ 261
++ E +L+ G E E Q + E Q + ++EE+ + ++E L K + ++
Sbjct: 1372 -QKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEII 1430
Query: 262 EEEP-------QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314
E+E Q + + +E +E++++L+ EL +Q+ E+ + R +QQ++RK +
Sbjct: 1431 EQEDLIKALHTQLEMQAKEHDERIKQLQ-VELCEMKQKPEEIGEESRAKQQIQRKLQAAL 1489
Query: 315 REQQEERREQQERREQQEERRE--QQLRREQEERREQQLRREQEEERREQQLRREQEEER 372
++E +E + +E+ R ++L + + Q + +E++ +L QEE
Sbjct: 1490 ISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERD 1549
Query: 373 R-----EQQLRREQQLR---REQQLRREQQLRREQQLRRE-QQLRREQQLRREQQLRREQ 423
+ ++ L Q L +L E +++L +E + L+ + + + +
Sbjct: 1550 KLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHK 1609
Query: 424 QLRREQE---EERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480
+L++E E + +E ER + ++ ++E+++ + TE +++E KQ + +Q
Sbjct: 1610 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQ 1669
Query: 481 E-EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539
E EE +E+ K + ++++ E E+ R E ++ E L +++L
Sbjct: 1670 EMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELE 1729
Query: 540 REQEE-----RREQLLKREEEKRLE--QERREQ-------RLKREQEERRDQLLKREEER 585
R + E ++ Q L E++ E Q+ + Q + E E+ D EE
Sbjct: 1730 RVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEG 1789
Query: 586 RQQRL-KREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ 644
Q + E+++ L + E + + + ++ + L+ +Q + R
Sbjct: 1790 TQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERI 1849
Query: 645 QQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQ---EQARERIKSRI 701
L E+Q+ +E E E+ L ++ + E + QE + +Q +E + SR+
Sbjct: 1850 AGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEEL-SRV 1908
Query: 702 PKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE 761
K + E E D + ++ ++ + G Q+ + ++EL E + + E
Sbjct: 1909 TKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSEL 1968
Query: 762 EQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQ------QREQRFLPEEE 815
E+ + + + + +SE ++ L +++ + A+E Q Q+E + L ++
Sbjct: 1969 EEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDC 2028
Query: 816 EKEQRRRQRRERE-KELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKW 874
+ Q + ER K L+F++ E Q + L+ ++ L + E R+ + Q +
Sbjct: 2029 IRYQEKISALERTVKALEFVQTESQ-------KDLEITKENLAQAVEHRK-KAQAELASF 2080
Query: 875 RWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEE 934
+ L++ + L L+++L+ ++ ++ + ++ + E+ E+R Q +E+ +E++
Sbjct: 2081 KVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQ-KDEDLERRLEQAEEKHLKEKK 2139
Query: 935 QLQQEEEQLLREE--REKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE 992
+Q++ + L RE+ E+ + + +KDK++QQ +E L + +
Sbjct: 2140 NMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFT------KS 2193
Query: 993 EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYR- 1051
LQ + ++++ E ++ WER++ D +Q +EE++ +E L+++ RQ
Sbjct: 2194 MSSLQDDRDRVIDEAKK------WERKF--SDAIQSKEEEIRLKEDNCSVLKDQLRQMSI 2245
Query: 1052 EEEELQQEEEQLLGEER--ETRRRQELERQYRKEEELQQEEEQLLREEPEKRR--RQERE 1107
EEL+ +L +++ E++ + E++ Q + + LQ E ++LL + E R +
Sbjct: 2246 HMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQN 2305
Query: 1108 RQCREEEELQQEEEQL--LREEREKRRRQE--LERQYREEE-EVQQEEEQLLREEPEKRR 1162
+ E EL+ ++QL L EK + Q+ LE R++E ++Q + + E + +
Sbjct: 2306 ELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQA 2365
Query: 1163 RQELERQYREEEELQQEE--------EQLLREEQEKRRQERERQYREEEELQRQKRKQRY 1214
+EL + EE +++++ E+ ++ + RQ+ +++ +E E L Q+ ++
Sbjct: 2366 SRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENI 2425
Query: 1215 RDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQS-QQDLQHLLGE 1273
E++ +K N + + K +EN Q + DS ++ S Q D ++G+
Sbjct: 2426 VLEEENKKAV-----DKTNQLMETLKTIK-KENIQQKAQLDSFVKSMSSLQNDRDRIVGD 2479
Query: 1274 QQERD---------REQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREE 1324
Q+ + ++Q + + EE + R + + K E RE+
Sbjct: 2480 YQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYRED 2539
Query: 1325 REEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKF--LEEEQR 1382
+ +++ +K E QL Q +E + + + + K +E E +++ R F L+EE++
Sbjct: 2540 LNQVITIKDSQQKQLLEVQLQQNKELEN-KYAKLEEKLKESEEANEDLRRSFNALQEEKQ 2598
Query: 1383 LRRQERERKFLKEEQQLR----CQEREQQLRQDRDRKFREEEQQL------SRQERDRKF 1432
+E E + Q R QE K +EEE S Q+R +
Sbjct: 2599 DLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAEL 2658
Query: 1433 REEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQ 1492
EE V++ E +K E E +L++E + + E E + E R +E EQ
Sbjct: 2659 EEELVCVQK-EAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQ 2717
Query: 1493 QLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQR---QRKFLQEEQQLRRQERGQQR 1549
+L ++ K +++S L+ + ++ +RK+ ++L + +
Sbjct: 2718 KLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLL 2777
Query: 1550 RQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEG 1609
++RD E EE LS E+ L +Q + + EQ + QL
Sbjct: 2778 NRERDALLSETAFSMNSTEENSLSHLEK-----LNQQLLSKDEQ---LLHLSSQLEDSYN 2829
Query: 1610 QQQ--------LRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQL 1661
Q Q L+ ERD + E E+ + E +Q + E + + L
Sbjct: 2830 QVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMS---SL 2886
Query: 1662 RHDRDRKFRE----EEQLLQEGEE---------QQLRRQERDRKFREEEQQLRRQERERK 1708
++DRDR +E ++Q LQ +E Q Q++ + F+ +++LR++
Sbjct: 2887 QNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLS-- 2944
Query: 1709 FLQEEQQLRRQEL-----ERKFREE-------------------EQLRQETEQEQLRRQE 1744
+ E QLR ++ ER+ +E+ +LR + Q Q + +
Sbjct: 2945 WQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQ 3004
Query: 1745 RYRKILEEEQLRPER------EEQQLRRQERD--RKFREEE-----------QLRQEREE 1785
R+ E P+ E + LR Q D ++ ++E QL +E+
Sbjct: 3005 YQRQASPETSASPDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEEKNT 3064
Query: 1786 QQLRSQESDRKFREEEQ---------LRQEREEQQLR------------PQQRDGKYRWE 1824
++ ++ + RE +Q E++ Q+L+ PQ+++G +R
Sbjct: 3065 LSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQELQAGPLNIDVAPGAPQEKNGVHR-- 3122
Query: 1825 EEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEE-EQKRRQERERKLREE 1883
+ + LR+ + A++Q + E ++L +EE +Q+ E + EE
Sbjct: 3123 ------KSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAAENALSVAEE 3176
Query: 1884 HIRRQQKEE---QRHRQVGEIKSQE 1905
IRR + E R +G +QE
Sbjct: 3177 QIRRLEHSEWDSSRTPIIGSCGTQE 3201
Score = 218 bits (555), Expect = 5e-56
Identities = 414/1978 (20%), Positives = 804/1978 (40%), Gaps = 301/1978 (15%)
Query: 116 EEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQS--EKQERLEQRD--RQRRDE 171
+ DQ P D +L +E QE +E EQ E ++ + Q+D Q++DE
Sbjct: 21 DTDQNMRAPLDPELHQESDMEFNNTTQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDE 80
Query: 172 ELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRR 231
L +EER+A + +++ K H + +L L + E K Q
Sbjct: 81 AL---------QEERKAADNKIKKLKLHA-----------KAKLTSLNKYIEEMKAQGGT 120
Query: 232 ERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQ----ELR 287
EE+ + K T E EK++ + LQE+EE + L+ Q +
Sbjct: 121 VLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHK-------LQEKEELISTLQAQLTQAQAE 173
Query: 288 RERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERR 347
+ Q + ++ + +QQL+ K+E Q + + Q E+ QQ+ RE++ R
Sbjct: 174 QPAQSSTEMEEFVMMKQQLQEKEE-------FISTLQAQLSQTQAEQAAQQVVREKDARF 226
Query: 348 EQQLR-REQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 406
E Q+R E E + Q E E +++ + L+R+ + E + R Q + QQ +
Sbjct: 227 ETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAE 286
Query: 407 LRREQQLRREQQLRREQQ-LRREQEEERHE-----QKHEQERREQRLK--REQEERRDWL 458
R + ++ QQ+ E LR E ER E +K E E E++L QEE L
Sbjct: 287 QRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLL 346
Query: 459 KREEETERHEQERRK-----QQLKRDQEEERRERWLKLEEEERREQ------QERREQQL 507
++ E+ + + E +Q + + EE+ L L++ + Q +++ + L
Sbjct: 347 EQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLL 406
Query: 508 RREQEERREQRLKRQEEEERLQQRLRSEQQ----LRREQEERREQL----LKREEEKRLE 559
+ + E+ + Q+ E++LQQ+ + Q L +Q E Q + E + +
Sbjct: 407 QDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVT 466
Query: 560 QERREQRLKR--EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERRE 617
+E KR E E + LL E + LK E E+ Q E R + +R
Sbjct: 467 EENIASLQKRVVELENEKGALLLSSIE--LEELKAENEKLSSQITLLEAQNRTGEADREV 524
Query: 618 QRL-------KREEPEEERRQQLLKSE-EQEERRQQQLRREQQERREQ----------RL 659
+ KR EE Q +L++ Q+ + L E +E +E+ +
Sbjct: 525 SEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKR 584
Query: 660 KREEEEERLEQRLKREHEEE----------------------RREQELAEEEQEQARERI 697
E + E L+Q+ ++ E E E L E+EQA
Sbjct: 585 AEEADHEVLDQKEMKQMEGEGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEH 644
Query: 698 KSRIPKWQWQLESEADARQSKVYSRPRKQEGQRR--------RQEQEEKRRRR----ESE 745
+SR E + V + KQ+G + + Q+E R + E E
Sbjct: 645 QSR-------TSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELE 697
Query: 746 LQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLR------ 799
L + + + + + +E+ + EE + SA L E+R++ L
Sbjct: 698 LNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELS 757
Query: 800 --AEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE------EQLQRRERAQQLQE 851
E R Q +Q + E + QRR + L E+ E + + + LQ
Sbjct: 758 MVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQN 817
Query: 852 EEDGLQ---EDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE 908
E D +Q +Q Q + Q ++ E +R RH + ++ + Q L +
Sbjct: 818 ELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRH-------ISSKVEELSQALSQ 870
Query: 909 EEEELQREER---EKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKK 965
+E E+ + ++ EK+R E +Q EE+ Q E E+ + +E+ + K
Sbjct: 871 KELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKT 930
Query: 966 LQQKEEQLLGEEPEKRRRQERE--------KKYRE--------EEELQQEEEQLLREERE 1009
L+++ L E K+ + E + + Y E +EELQ E + LL++E E
Sbjct: 931 LKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFD-LLKKENE 989
Query: 1010 KRRRQEWERQYRKKDELQQ----EEEQLLREEREKRRLQERERQYREEEELQQEEEQLLG 1065
+R+R+ +K+ LQ+ EEE ++ K+ + E + E EE ++ +E
Sbjct: 990 QRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKE--YS 1047
Query: 1066 EERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQC---REEEELQQEEEQ 1122
E+ T + QE+E ++ ++ E Q +R++ E++ E + Q + + LQ + Q
Sbjct: 1048 EKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQ 1107
Query: 1123 LLREEREKRRRQELERQY-------REEEEVQQEEEQLLREEP----EKRRRQELERQY- 1170
+ + E Q + ++ + + V +E ++ P + + ELE +
Sbjct: 1108 IDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKIL 1167
Query: 1171 ---REEEELQQEEEQLL--REEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKW 1225
+E+E+LQ++ ++ L R+ K+ QE+ER REE + Q+ + D++S
Sbjct: 1168 ALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQS---- 1223
Query: 1226 QWEPEKENAVRDNKVYCKGRENEQFRQLE-------DSQLRDRQSQQDLQHLLGEQQERD 1278
E EN +Q RQL+ D +L Q+ G ++
Sbjct: 1224 ---KENENI------------GDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLF 1268
Query: 1279 REQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKF 1338
+ E+ Q + E A + + K L+E EK E + K
Sbjct: 1269 KATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEK---VELELKV 1325
Query: 1339 REEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQ 1398
L ++ E+ + QE+ K E + K + E + + ++K + Q
Sbjct: 1326 SSTTSELTKKSEEVFQLQEQINKQGLE-----IESLKTVSHEAEVHAESLQQKLESSQLQ 1380
Query: 1399 LRCQEREQQLRQDRDRKFREEEQQLSRQERDRKF---REEEQQVRRQERERKFLEEE--- 1452
+ E ++L+ K E ++ +S++E D + + E++ + + + +E+E
Sbjct: 1381 IAGLEHLRELQP----KLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLI 1436
Query: 1453 QQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQE 1512
+ L + + +E ++ +++ + + +++ + EE + +Q+ RK + + +E
Sbjct: 1437 KALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESR--AKQQIQRKLQAALISRKE 1494
Query: 1513 --PERKFLEEEQQLHR---QQRQRKFLQEEQQLRRQERGQQR--------RQDRDRKFRE 1559
E K L+EE L R ++ + E Q+ Q + + +++RD+ E
Sbjct: 1495 ALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITE 1554
Query: 1560 EEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLR-QERD 1618
+ R E Q LS K LE E + K +++ + L+ + + QE+
Sbjct: 1555 MD--RSLLENQSLSSSCESLKLALE----GLTEDKEKLVKEIESLKSSKIAESTEWQEKH 1608
Query: 1619 RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQE 1678
++ +++ ++L + E + ER + +E Q +QE +LR K +E E+ LQE
Sbjct: 1609 KELQKEYEILLQSYENVSNEAERIQHVVEAVRQ-EKQELYGKLRSTEANK-KETEKQLQE 1666
Query: 1679 GEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE 1738
E++ +E+ RKF + +QQ K L+ E++ + R E +T +E
Sbjct: 1667 AEQEMEEMKEKMRKFAKSKQQ--------KILELEEE------NDRLRAEVHPAGDTAKE 1712
Query: 1739 QLRRQERYRKILEEEQLRPEREEQQLRRQ------ERDRKFREEEQLRQEREEQQLRSQE 1792
+ ++EE R + E + L ++ E+D E + L+ + E +
Sbjct: 1713 CMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQAN 1772
Query: 1793 SDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQ---EQRLRQERDRQYRAEE 1849
+ + + Q E Q P + + E++ L + + + + + +
Sbjct: 1773 LEATEKHDNQTNVTEEGTQSIPGETE-----EQDSLSMSTRPTCSESVPSAKSANPAVSK 1827
Query: 1850 QFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
F++ ++ Q++ Q +E+ E E++ +E Q E +++ + +I +++G+
Sbjct: 1828 DFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEF--SQTLENEKNTLLSQISTKDGE 1883
Score = 217 bits (553), Expect = 8e-56
Identities = 388/1908 (20%), Positives = 811/1908 (42%), Gaps = 281/1908 (14%)
Query: 196 CKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRK 255
C G P+ E+ + LE ++ ++K Q+ + + ++ +EKE RE + ++
Sbjct: 1151 CTGSSEHWKPELEE--KILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQ 1208
Query: 256 EEE--KLQEEEPQRQRELQEEEEQLRKLE---RQELRRERQEEEQQQQRLRR---EQQLR 307
+++ +LQE+ ++ +E + +QLR+L+ R+ + + +QQ+ E+ L
Sbjct: 1209 KDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLF 1268
Query: 308 RKQEEERREQQEERR-------EQQERREQQEERREQQLRREQEERREQQLRREQEEERR 360
+ E+ + E ++ Q Q++ + +E +++ E +
Sbjct: 1269 KATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSST 1328
Query: 361 EQQLRREQEEERREQQLRREQQLRRE--QQLRREQQLRRE---QQLRREQ-QLRREQQLR 414
+L ++ EE + Q+ +Q L E + + E ++ E Q+L Q Q+ + LR
Sbjct: 1329 TSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLR 1388
Query: 415 REQ-QLRREQQLRREQEEE---RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE 470
Q +L Q+L ++EE+ Q E+E +++ E E+ D +K + +
Sbjct: 1389 ELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAK 1448
Query: 471 RRKQQLKRDQEE--ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE--- 525
+++K+ Q E E +++ ++ EE R +QQ +R+ Q + + K +EE
Sbjct: 1449 EHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSL 1508
Query: 526 -----ERLQQRLRS-EQQLRREQEER-----REQLLKREEEKRLEQERRE---------- 564
ERL + L E Q+ + +E+ R LL+ E +K + + R
Sbjct: 1509 ARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSS 1568
Query: 565 -QRLKREQE---ERRDQLLKREEERRQQRL-------KREQEERLEQRLKREEVERLEQE 613
+ LK E E +++L+K E + ++ ++ +E + E + + E + E
Sbjct: 1569 CESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNE 1628
Query: 614 ERREQRLK---REEPEE-------------ERRQQLLKSEEQEERRQQQLRREQQERREQ 657
R Q + R+E +E E +QL ++E++ E ++++R+ + ++++
Sbjct: 1629 AERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQK 1688
Query: 658 RLKREEEEERLEQRLKREHEEERREQELA-------EEEQEQARERIKSRIPKWQWQLES 710
L+ EEE +RL + + + E +EE E+ + ++ K+Q L S
Sbjct: 1689 ILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQ-SLMS 1747
Query: 711 EADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQ 770
E D+ +V + EG +Q E + +++ EE + EEQ D
Sbjct: 1748 EKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQ--DSLSM 1805
Query: 771 WQAEEKSERGRQRLSARPPLREQ-----------------RERQLRAEERQQREQRFLPE 813
SE SA P + + +ER EE +Q+ + F
Sbjct: 1806 STRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQT 1865
Query: 814 -EEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872
E EK Q ++ EL+ L+EE QQ+QEE + + +E ++ ++
Sbjct: 1866 LENEKNTLLSQISTKDGELKMLQEEVTKMNLLN-QQIQEELSRVTKLKETAEEEKDDLEE 1924
Query: 873 KWRWQLEEERKRRRHTLYAKPALQEQLRKE---------QQLLQEEEEELQREEREKRR- 922
+ QL E + Y + Q++ E ++ + E EEE Q+ +EK +
Sbjct: 1925 RLMNQLAELNGSIGN--YCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKV 1982
Query: 923 RQEQERQYREEEQLQQEE----------EQLLREEREKRRRQERE--RQYRKDKKLQQKE 970
E ++Y E+ Q Q+E ++LL+E++++ ++ +++ R K L++
Sbjct: 1983 ESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTV 2042
Query: 971 EQLLGEEPEKRRRQEREKK-------YREEEELQQEEEQLLREEREKRRRQEWERQYRKK 1023
+ L + E ++ E K+ +R++ + + ++L ++ + + + K
Sbjct: 2043 KALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLK 2102
Query: 1024 DELQQEEEQLLREEREK-----RRLQERERQYREEEELQQEEEQLLGEERETRRRQELER 1078
ELQ +E + + ++K RRL++ E ++ +E++ QE+ L E+ E
Sbjct: 2103 KELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEI 2162
Query: 1079 QY---RKEEELQQEEEQL----------------LREEPEKRRRQERERQCREEEELQQE 1119
Q +K++E+QQ +E L L+++ ++ + ++ + + + +Q +
Sbjct: 2163 QVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSK 2222
Query: 1120 EEQL-LREEREKRRRQELERQYREEEEVQQEEEQLLREEP--EKRRRQELERQYREEEEL 1176
EE++ L+E+ + +L + EE++ +L ++ E + + E++ Q + + L
Sbjct: 2223 EEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTL 2282
Query: 1177 QQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVR 1236
Q E ++LL + +E R Q E +L+ + + + DQ +DL E KE
Sbjct: 2283 QGENKELLSQLEETRHLYHSSQ-NELAKLESELKSLK----DQLTDLSNSLEKCKEQ--- 2334
Query: 1237 DNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEE 1296
K +G +Q +++S+ Q + DLQ E R E+ + Q+ +
Sbjct: 2335 --KGNLEGIIRQQEADIQNSKFSYEQLETDLQ-ASRELTSRLHEEINMKEQKIISLLSGK 2391
Query: 1297 EQ--------LEREEQKEAKRRDRK-SQEEKQLLREEREEKRRRQETDRKFREEEQLLQE 1347
E+ L ++ KE K + SQEE++ + E E K+ +T++ + + +E
Sbjct: 2392 EEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKE 2451
Query: 1348 REEQPLR-----------RQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEE 1396
+Q + + +RDR + + + LE++Q ++ E LKEE
Sbjct: 2452 NIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEE 2511
Query: 1397 -QQLRCQERE---QQLRQDRDR-KFREE-EQQLSRQERDRKFREEEQQVRRQERERKFLE 1450
+ LR + + + D + ++RE+ Q ++ ++ +K E Q + +E E K+ +
Sbjct: 2512 IRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAK 2571
Query: 1451 EEQQLRQ--ERHRKFREEEQLLQEREEQQLHRQERDRKF-----------LEEEQQLRRQ 1497
E++L++ E + R LQE E+Q L ++ K L+EE L
Sbjct: 2572 LEEKLKESEEANEDLRRSFNALQE-EKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLY 2630
Query: 1498 ERDRKFREQELR-------SQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQ------E 1544
K +E+E+ S + LEEE +++ +K + E +L+++ +
Sbjct: 2631 HAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHD 2690
Query: 1545 RGQQRRQDRDRKFREEEQLRQ--EREEQQLSRQERDRKFRLEEQKVRRQ----------- 1591
G R + + R E R E E++ L + ++ + Q R
Sbjct: 2691 AGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHA 2750
Query: 1592 -----EQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQL-HRQERDRKF 1645
E +RK+ ++L + + Q L +ERD E + EE L H ++ +++
Sbjct: 2751 NEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQL 2810
Query: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705
L ++ QL + + +++ + F + LQ + E KFR+ E+ +R
Sbjct: 2811 LSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELE---KFRKSEEGKQRSAA 2867
Query: 1706 ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLR 1765
+ E Q ++ + + ++L +E + Q + + ++I E L+ + +E Q
Sbjct: 2868 QPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQ-- 2925
Query: 1766 RQERDRKFR-EEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWE 1824
++ + F+ +E+LRQE Q E QLR E+ WE
Sbjct: 2926 --DKTKAFQIMQEELRQENLSWQ----------HELHQLRMEKSS-------------WE 2960
Query: 1825 EEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKR 1872
+ +++EQ ++D+Q + + +S + + + + Q++
Sbjct: 2961 IHERRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQ 3008
Score = 206 bits (525), Expect = 1e-52
Identities = 397/2007 (19%), Positives = 816/2007 (40%), Gaps = 217/2007 (10%)
Query: 80 KVAQACYYALGQATGLD---EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQR 136
K+ + +A + T L+ EE +A+ ++L Q E+Q + EE ++
Sbjct: 92 KIKKLKLHAKAKLTSLNKYIEEMKAQGG---TVLPTEPQSEEQLSKHDKSSTEEEMEIEK 148
Query: 137 RRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREE----------R 186
+ K QE+E ++ + Q + + + EE +Q+ QE+EE +
Sbjct: 149 IKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQ 208
Query: 187 RAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEW 246
E+ Q + F + +L ELL+L + E + Q++ R + EE E+
Sbjct: 209 TQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESL 268
Query: 247 RKRETVLRKEEEKLQEEEPQRQ---RELQEEEEQLRKLERQELRRERQE-----EEQQQQ 298
R V+ +++L E + Q ++LQ+ E + L R + ER+E E+ + +
Sbjct: 269 VGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTL-RNTVETEREESKILLEKMELE 327
Query: 299 RLRREQQLRRKQEEERR--EQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE 356
R+ QEE EQ E+ + Q E + EQ+ + E EE+ L ++
Sbjct: 328 VAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKT 387
Query: 357 EERREQQLRREQEEERREQQLRREQQLRREQQLRR-EQQLRRE-----QQLRREQQLRRE 410
+ + +++ + Q + EQ ++ Q +++ E QL+++ Q L R + E
Sbjct: 388 GQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHE 447
Query: 411 --------------QQLRREQQLRREQQLRREQEEER----------HEQKHEQERREQR 446
Q E+ + Q+ E E E+ E K E E+ +
Sbjct: 448 TASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQ 507
Query: 447 LKREQEERRDWLKREEETE-----------RHEQERRKQQLKRDQEEERRE-RWLKLEEE 494
+ + + R E +E +E + L+ ++ +E L LE +
Sbjct: 508 ITLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMK 567
Query: 495 ERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL-LKRE 553
E +E+ + QL+ ++ E + + Q+E ++++ + +++ E+ + L
Sbjct: 568 EAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEGIAPIKMKVFLEDTGQDFPLMPN 627
Query: 554 EEKRLEQERREQRLKREQEERRDQL--------LKREEERRQQRLK---------REQEE 596
EE L +EQ Q +++ LK ++ + L +++ E
Sbjct: 628 EESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELE 687
Query: 597 RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE 656
RL+ ++ E+ + +E E+ L + E QL++ ++ E R+
Sbjct: 688 RLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERD 747
Query: 657 QRLKREEE----------EERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQW 706
Q L + +E ++LE L + R + E E+I S
Sbjct: 748 QLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHS------- 800
Query: 707 QLESEADARQSKV-YSRPRKQEGQRRRQEQEEKRRRRESELQWQEE---ERAHRQQQEEE 762
L EA ++ K+ + + Q + EQ R +S+LQ +E E A R +
Sbjct: 801 -LSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISS 859
Query: 763 QRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRR 822
+ + + +E +L + +Q E+ QQ + E+ Q
Sbjct: 860 KVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNE 919
Query: 823 QRREREKELQFLEEE-EQLQRRERAQQLQEEED-----GLQEDQERRRSQEQRRDQKWRW 876
++ E++ L+E+ L R E A++ Q EED GL+++ + Q ++ +
Sbjct: 920 EKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQH 979
Query: 877 Q---LEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQER-QYRE 932
+ L++E ++R+ L A +++L + L+EE L+ E +++ E ER + E
Sbjct: 980 EFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEE 1039
Query: 933 EEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE 992
+++ ++ E+ + + ++ ++ K+ +LQ + L + + + Q K+ +
Sbjct: 1040 DKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQ 1099
Query: 993 EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE------------EREK 1040
+ + + LL+ E + + + D + L++E E K
Sbjct: 1100 TLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWK 1159
Query: 1041 RRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEK 1100
L+E+ +E+E Q++ Q E T R+ L++ KE L++E +Q +++
Sbjct: 1160 PELEEKILALEKEKEQLQKKLQ----EALTSRKAILKKAQEKERHLREELKQ--QKDDYN 1213
Query: 1101 RRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREE-EEVQQEEEQLLREEPE 1159
R +++ + Q +E E + + QL + RE + +E EE L + +
Sbjct: 1214 RLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQ 1273
Query: 1160 KRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDE-D 1218
+ LE + E+ L+ + + + + E E+++ + + E
Sbjct: 1274 HHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELT 1333
Query: 1219 QRSDLKWQWEPE-KENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQ-QDLQHLLGEQQE 1276
++S+ +Q + + + + + E E + +L Q Q L+HL Q +
Sbjct: 1334 KKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPK 1393
Query: 1277 RDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEE------KQLLREEREEKRR 1330
D Q+ ++ D + + E+E + + QE+ QL + +E R
Sbjct: 1394 LDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDER 1453
Query: 1331 RQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQE--QGRKFLEEEQRLRRQ-- 1386
++ + E +Q +E E+ +Q+ RK + + +E + K L+EE L R
Sbjct: 1454 IKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTI 1513
Query: 1387 ERERKFLKE-EQQLRCQEREQQ--------LRQDRDRKFRE------EEQQLSRQERDRK 1431
ER K L + E Q+ Q +E+ L+++RD+ E E Q LS K
Sbjct: 1514 ERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLK 1573
Query: 1432 F------REEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDR 1485
++E+ V+ E + E QE+H++ ++E ++L + E + ER +
Sbjct: 1574 LALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQ 1633
Query: 1486 KFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHR-QQRQRKFLQEEQQ--LRR 1542
+E +Q +QE K R E +E E++ E EQ++ +++ RKF + +QQ L
Sbjct: 1634 HVVEAVRQ-EKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILEL 1692
Query: 1543 QERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQ-----EQERKF 1597
+E + R + ++ + S +E + ++E + + ++ ++
Sbjct: 1693 EEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSL 1752
Query: 1598 MEDEQQLRRQ-EGQQQLRQERDRKFREDEQLLQEREEQQL---HRQERDRKFLEEEPQLR 1653
E+ Q L+ Q EG + + + D Q E Q +E+D + P
Sbjct: 1753 SEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCS 1812
Query: 1654 RQEREQQ----------LRHDRDRKFREEEQLLQEG----EEQQLRRQERDRKFREEE-- 1697
+ HD + ++ L+E EE++ + +E + E+
Sbjct: 1813 ESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNT 1872
Query: 1698 --QQLRRQERERKFLQEE---QQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEE 1752
Q+ ++ E K LQEE L Q+++ + +L++ E+E+ +ER L E
Sbjct: 1873 LLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAE 1932
Query: 1753 -----EQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQER 1807
+ + Q++ + + + + ++ E EE+ + Q K + E ++R+E
Sbjct: 1933 LNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEE--KQQLVKEKTKVESEIRKEY 1990
Query: 1808 EEQQLRPQQRDG-KYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQ 1866
E+ Q+ G K +E Q L+E++Q ++Q + R +E+ + E++ + E Q
Sbjct: 1991 LEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK-ALEFVQ 2049
Query: 1867 EEEQKRRQERERKLRE--EHIRRQQKE 1891
E QK + + L + EH ++ Q E
Sbjct: 2050 TESQKDLEITKENLAQAVEHRKKAQAE 2076
Score = 157 bits (397), Expect = 1e-37
Identities = 258/1334 (19%), Positives = 550/1334 (41%), Gaps = 151/1334 (11%)
Query: 620 LKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEE 679
L ++ ++ + L E +E + Q++ +E+ E+ L+ ++++ +
Sbjct: 16 LSGDDDTDQNMRAPLDPELHQESDMEFNNTTQEDVQERLAYAEQLVVELKDIIRQKDVQL 75
Query: 680 RREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEG------QRRRQ 733
+++ E +EE++ A +IK + +L ++A Y K +G + + +
Sbjct: 76 QQKDEALQEERKAADNKIK------KLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQSE 129
Query: 734 EQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQ 793
EQ K + +E + + E+ H+ Q++EE L
Sbjct: 130 EQLSKHDKSSTEEEMEIEKIKHKLQEKEE---------------------------LIST 162
Query: 794 RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE-EQLQRRERAQQLQEE 852
+ QL + +Q Q E EE ++Q +E+E+ + L+ + Q Q + AQQ+ E
Sbjct: 163 LQAQLTQAQAEQPAQS-STEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVRE 221
Query: 853 EDGLQEDQERRRSQE--------------QRRDQKWRWQLEEERKRRRHTLYAKPALQEQ 898
+D E Q R E Q++ + + +LEE + LQ++
Sbjct: 222 KDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQE 281
Query: 899 LRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERER 958
L +Q Q ++LQ+ E E + REE ++ E+ +L ER+ +E
Sbjct: 282 LTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEE 341
Query: 959 QYRKDKKLQQKEEQLLGEEP-----EKRRRQEREKKYREEEELQQEEEQL------LREE 1007
+ ++ +Q + E E++ + E E+K LQ+ ++L L+++
Sbjct: 342 MHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQ 401
Query: 1008 REKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEE 1067
K + + E+ + +QQ E+QL ++ +E + R + E Q + E
Sbjct: 402 NSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEG 461
Query: 1068 RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127
+ + + ++ EL+ E+ LL E + + + L + + + +
Sbjct: 462 TQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEAD 521
Query: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE 1187
RE ++ + ++ + +L E ++ +EL E +E Q+E L +
Sbjct: 522 REVSEISIVDIANKRSSSAEESGQDVL-ENTFSQKHKELSVLLLEMKEAQEEIAFLKLQL 580
Query: 1188 QEKRRQERERQYREEEELQRQ--------KRKQRYRDEDQRSDLKWQWEP-----EKENA 1234
Q KR +E + + +++E+++ K K D Q L E EKE A
Sbjct: 581 QGKRAEEADHEVLDQKEMKQMEGEGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQA 640
Query: 1235 VRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFP 1294
++ + R +E+ L D+ + + ++QD L + + + + + +
Sbjct: 641 STEH----QSRTSEEI-SLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILE 695
Query: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKF----REEEQLLQEREE 1350
E + ++ K D K++E L + E K+ F E +QLL + +E
Sbjct: 696 LELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKE 755
Query: 1351 QPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLR- 1409
+ ELR Q + + E L ER+R+ E Q +Q+
Sbjct: 756 LSM----------VTELRAQVK-----QLEMNLAEAERQRRLDYESQTAHDNLLTEQIHS 800
Query: 1410 ---QDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREE 1466
+ + + + E Q + +F E+ +R + + + E E ER R +
Sbjct: 801 LSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSK 860
Query: 1467 -EQLLQEREEQQLHRQERDRKFLEEEQQLRR-----QERDRKFREQELRSQEPERKFLEE 1520
E+L Q +++L + D+ LE+++ + +E+D++ E E + EE
Sbjct: 861 VEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEE 920
Query: 1521 EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQ----QLSRQE 1576
+ L + + K ++ L R E ++ + + D + L+Q +E Q+S++E
Sbjct: 921 KFSLGVEIKTLK--EQLNLLSRAEEAKKEQVEEDNEV--SSGLKQNYDEMSPAGQISKEE 976
Query: 1577 RDRKFRL--EEQKVRRQEQERKFMEDEQQLRR-QEGQQQLRQERDRKFREDEQLLQEREE 1633
+F L +E + R+++ + + ++ L+R +++L +D +E L E E
Sbjct: 977 LQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIP--LSETER 1034
Query: 1634 QQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKF 1693
++ + ++++ E+ + QE E L+ K E + + ++ EE+ ++
Sbjct: 1035 GEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALV 1094
Query: 1694 REEEQQLRRQERERKFLQEE--------QQLRRQELERKFREEEQLRQET---EQEQLRR 1742
++ Q L+ + + LQ E Q+L + + L +ET
Sbjct: 1095 KQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGS 1154
Query: 1743 QERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQ 1802
E ++ LEE+ L E+E++QL+++ ++ + L+ ++QE +R REE
Sbjct: 1155 SEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILK--------KAQEKERHLREE-- 1204
Query: 1803 LRQEREEQQLRPQQRDGKYRWEEEQL--QLEEQEQRLRQERDRQYRAEEQFATQEKSRRE 1860
L+Q++++ +Q D + + E E + QL + + ++R+ D + + +Q + +
Sbjct: 1205 LKQQKDDYNRLQEQFDEQSK-ENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGL 1263
Query: 1861 EQELWQEEEQKRRQ 1874
E+ L++ EQ Q
Sbjct: 1264 EEPLFKATEQHHTQ 1277
Score = 139 bits (349), Expect = 4e-32
Identities = 267/1298 (20%), Positives = 542/1298 (41%), Gaps = 205/1298 (15%)
Query: 798 LRAEERQQREQRFLPEEEEKEQRRRQRRER-EKELQFLEEEEQLQRRERAQQLQEEEDGL 856
L E Q+ + F +E Q R E+ EL+ + ++ +Q +++ + LQEE
Sbjct: 30 LDPELHQESDMEFNNTTQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAA 89
Query: 857 QEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQRE 916
++ + + + +EE + + L +P +EQL K + EEE E+
Sbjct: 90 DNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEI--- 146
Query: 917 EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQ--ERERQYRKDKKLQQKEE--- 971
E+ K + QE+E E + + QL + + E+ + E E ++LQ+KEE
Sbjct: 147 EKIKHKLQEKE------ELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFIS 200
Query: 972 ----QLLGEEPEKRRRQE-REKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK-KDE 1025
QL + E+ +Q REK R E +++ E++LL+ + E +++ R + +
Sbjct: 201 TLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRK 260
Query: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
L++ EE L+ + LQ+ + ++ ++ Q + E T R E
Sbjct: 261 LEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNT---------LRNTVE 311
Query: 1086 LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE-EREKRRRQELERQYR--E 1142
++EE ++L E+ E + + LQ+E LL + E+ + + ELE +Y E
Sbjct: 312 TEREESKILLEKMELEVAERK----LSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALE 367
Query: 1143 EEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREE 1202
++ + EE+ ++ QEL+ + L+ + +LL+++ E+ Q + + E
Sbjct: 368 QKHKAEMEEKTSHILSLQKTGQELQSAC---DALKDQNSKLLQDKNEQAVQSAQTIQQLE 424
Query: 1203 EELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE----------NEQFRQ 1252
++LQ++ ++ R L+ Q E + + D VY +G + ++ +
Sbjct: 425 DQLQQKSKE--ISQFLNRLPLQ-QHETASQTSFPD--VYNEGTQAVTEENIASLQKRVVE 479
Query: 1253 LEDSQLRDRQSQQDLQHLLGEQQERDRE----QERRRWQQRDRHFPEEEQLEREEQKEAK 1308
LE+ + S +L+ L E ++ + + + R + DR E ++ A
Sbjct: 480 LENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDI-----AN 534
Query: 1309 RRDRKSQEEKQLLREEREEKRRRQET----DRKFREEEQLLQEREEQPLRRQERDRKFRE 1364
+R ++E Q + E ++ ++ + + K +EE + + Q R +E D + +
Sbjct: 535 KRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLD 594
Query: 1365 EELRHQEQGRKFLEEEQRLRRQERERKFL---KEEQQLRCQEREQQLRQDRDRKFRE--- 1418
++ Q +G + ++ ++ + F EE L E+EQ + + R E
Sbjct: 595 QKEMKQMEGEGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISL 654
Query: 1419 ----EEQQLSRQERDRKF----------REEEQQVRRQ--ERERKFLEEEQQLRQERHRK 1462
E + ++Q+ D+ ++E ++++ Q E E F + ++ + K
Sbjct: 655 NDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEK 714
Query: 1463 FREEEQLLQEREEQQLHRQERDRKFL---EEEQQLRRQERDRKFREQELRSQEPERKFLE 1519
+E L Q EE + + F EE QL Q ++ ELR+Q +
Sbjct: 715 AKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSM-VTELRAQVKQL---- 769
Query: 1520 EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQ---DRDRKFREEEQLRQEREEQQLSRQE 1576
E L +RQR+ E Q +Q + K + E L+ E ++ QL E
Sbjct: 770 -EMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSE 828
Query: 1577 RDRKFRLEEQKVRRQEQERKFMEDEQQLRR-----QEGQQQLRQERDRKFREDEQLLQER 1631
+ R + +++ +E E +E +++R +E Q L Q+ + D+ LL+++
Sbjct: 829 QSTLIRSLQSQLQNKESE--VLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKK 886
Query: 1632 EEQQLHRQERDRKFLE-EEPQLRRQEREQQLRHDRD------RKFREEEQLLQEGEEQQL 1684
+ + +Q + K + E E+ QL ++ + +E+ LL EE +
Sbjct: 887 RDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKK 946
Query: 1685 RRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKF----REEEQLRQETEQEQL 1740
+ E D E L++ E + Q+ ++EL+ +F +E EQ +++ + +
Sbjct: 947 EQVEEDN---EVSSGLKQNYDE---MSPAGQISKEELQHEFDLLKKENEQRKRKLQAALI 1000
Query: 1741 RRQERYRKI--LEEEQLRPERE-EQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKF 1797
R+E +++ LEEE + E ++++ E +R EE++ +E E+ + S+ + +
Sbjct: 1001 NRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEI 1060
Query: 1798 REEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYR------AEEQF 1851
++ + ++ E Q + + K EE+ L +Q + Q++ Q +E Q
Sbjct: 1061 YLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQA 1120
Query: 1852 ATQE----------------------------------KSRREEQELWQEEEQ------- 1870
Q+ K EE+ L E+E+
Sbjct: 1121 IIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKL 1180
Query: 1871 -----------KRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLE----- 1914
K+ QE+ER LREE +++Q+ + R ++ + +S+E + G L
Sbjct: 1181 QEALTSRKAILKKAQEKERHLREE-LKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQ 1239
Query: 1915 ---------PGTHQ---FASVPVRSSPLYEYIQEQRSQ 1940
P T Q +S P PL++ ++ +Q
Sbjct: 1240 VRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQ 1277
Score = 105 bits (262), Expect = 4e-22
Identities = 222/1148 (19%), Positives = 443/1148 (38%), Gaps = 242/1148 (21%)
Query: 89 LGQATGLDEEKRARCDGKESLLQDRRQEE-----DQRRFEPRDRQLEEEPGQRRRQKRQE 143
L QA ++ +A + LL D + E D + + + +E + +QK ++
Sbjct: 2063 LAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDED 2122
Query: 144 QERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEE 203
ER L + EE+ K+++ Q E+L R+E EE E + + K E ++
Sbjct: 2123 LERRLEQAEEKHLKEKKNMQ-------EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQ 2175
Query: 204 FPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEE-KLQE 262
+ +L + ++ +DRV E ++ E + + + KEEE +L+E
Sbjct: 2176 LQENLDSTVTQLAAFTKS-----MSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKE 2230
Query: 263 EE----PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRK-------QE 311
+ + R++ E+L K+ L ++Q E + Q E QL++K +
Sbjct: 2231 DNCSVLKDQLRQMSIHMEEL-KINISRLEHDKQIWESKAQT---EVQLQQKVCDTLQGEN 2286
Query: 312 EERREQQEERREQQERREQQEERREQQLR--REQEERREQQLRREQEEERREQQLRREQE 369
+E Q EE R + + + E +L+ ++Q L + +E++ + + R+QE
Sbjct: 2287 KELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQE 2346
Query: 370 EERRE-----QQLRREQQLRREQQLRREQQLRREQQL------RREQQLR---REQQLRR 415
+ + +QL + Q RE R +++ ++Q +E+ ++ E + +
Sbjct: 2347 ADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQH 2406
Query: 416 EQQLRREQQLRREQEEER----HEQKHEQERREQRLKREQEERRDWLKREEETERHEQER 471
+++++ + L ++EEE E K ++ Q ++ + +++ ++++ + + +
Sbjct: 2407 DKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSM 2466
Query: 472 RKQQLKRD------QEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE 525
Q RD Q+ E R + LE+++ ++ +L+ E R E
Sbjct: 2467 SSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSEN 2526
Query: 526 ERLQQRL-------------RSEQQ-----LRREQEERREQLLKREEEKRLEQERREQRL 567
+L L + QQ ++ +Q + E + EEK E E + L
Sbjct: 2527 AKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDL 2586
Query: 568 KRE----QEERRD-----QLLKREEERRQQRLKREQEE------RLEQRLKREEVERLEQ 612
+R QEE++D + LK + +++ QEE + ++K EEV RL
Sbjct: 2587 RRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSA 2646
Query: 613 EERREQRLKREEPEE---ERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEER-- 667
Q+ E EE +++ K E E++ +++L+ + R + E EER
Sbjct: 2647 LFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVA 2706
Query: 668 --------LEQRLKREHEEER----------REQELAEEEQEQARERIKSRIPKWQWQLE 709
+EQ+L +E + R + ++ A E + K+ L+
Sbjct: 2707 ELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLK 2766
Query: 710 SEADARQSKVYSRPRK---QEGQRRRQEQEEKRRRRESELQWQ----EEERAHRQQQEEE 762
A ++ + +R R E EE +L Q +E+ H Q E+
Sbjct: 2767 ELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLED 2826
Query: 763 Q----------------RRDFTW-QWQAEEKSERGRQRLSARPP---------------L 790
RD W + + KSE G+QR +A+P L
Sbjct: 2827 SYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSL 2886
Query: 791 REQRERQLRAEERQQREQRFLPEEEEKEQ------RRRQRREREKELQFLEEE---EQLQ 841
+ R+R L+ E + +Q++L +E + + ++ +++ K Q ++EE E L
Sbjct: 2887 QNDRDRLLK--ELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLS 2944
Query: 842 RRERAQQLQEEEDGLQEDQERRRSQ--------------------EQRRDQKWRWQLEEE 881
+ QL+ E+ + + R + Q E R L+ +
Sbjct: 2945 WQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQ 3004
Query: 882 RKRRRHT-LYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQ-------------- 926
+R+ A P + L E +LL+ + + +E +K R +Q
Sbjct: 3005 YQRQASPETSASPDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEEKNT 3064
Query: 927 --------ERQYREEEQ-----------LQQEEEQLL-------------REEREKRRRQ 954
+ RE +Q L+++ ++L +E+ R+
Sbjct: 3065 LSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQELQAGPLNIDVAPGAPQEKNGVHRKS 3124
Query: 955 ERERQYRKDKKLQQKEEQLLGEEPE-----KRRRQEREKKYREEEELQQEEEQLLREERE 1009
+ E + + ++QL E K +ER+++ E L EEQ+ R E
Sbjct: 3125 DPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAAENALSVAEEQIRRLE-- 3182
Query: 1010 KRRRQEWE 1017
EW+
Sbjct: 3183 ---HSEWD 3187
Score = 74.7 bits (182), Expect = 8e-13
Identities = 158/778 (20%), Positives = 307/778 (39%), Gaps = 133/778 (17%)
Query: 31 KDLKNLLEREFGA-VLRRPHDPKTVDLILELLDL-------DSNGRVDFNEFLLFIFKVA 82
K+L+NLL +E ++ + K VD +L++ + + + F+ + +
Sbjct: 2411 KELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQ 2470
Query: 83 QACYYALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPR------------DRQLE 130
+G L+E + K+ L+Q+ E ++ + E R + +L+
Sbjct: 2471 NDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLD 2530
Query: 131 EEPGQRRR-----------QKRQEQERELAEGEEQSEKQERLEQR--DRQRRDEELWRQR 177
E Q R Q++Q E +L + +E K +LE++ + + +E+L R
Sbjct: 2531 AELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSF 2590
Query: 178 QEWQEREERRAEE-EQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRR----E 232
QE ++ ++E E L+ T + ++ L + K +EE+ +
Sbjct: 2591 NALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSS 2650
Query: 233 RQDRVFQEEEEKEWRKRET-----------------------VLRKEEEKLQEEEPQRQR 269
Q R+ + EEE ++E ++R E E +E + R
Sbjct: 2651 SQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELAR 2710
Query: 270 ELQEEEEQLRKLERQE----------------LRRERQEEEQQQQRLRREQQLRRKQEEE 313
+L E E++L + ++ L+ R ++ L+R+ K+ +
Sbjct: 2711 DLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQ 2770
Query: 314 RREQQEERREQ--------------QERREQQEERREQQLRREQEE------RREQQLRR 353
+EQ RE+ +E E+ QQL + E+ + E +
Sbjct: 2771 LKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQ 2830
Query: 354 EQEEERREQQLRREQEEERRE-QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 412
Q + L+ E++ E ++ R+ ++ ++ + Q L++ + +
Sbjct: 2831 VQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDR 2890
Query: 413 LRREQQLRREQQ--LRREQE-EERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQ 469
R ++L+ QQ L+ QE E H K + + + + K Q + + L++E + +HE
Sbjct: 2891 DRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEE-LRQENLSWQHEL 2949
Query: 470 ERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRRE--QEERREQRLKRQEEEER 527
+ + + + ERR + L ++QQ Q L RE + Q LK Q + +
Sbjct: 2950 HQLRMEKSSWEIHERRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQA 3009
Query: 528 LQQRLRS---EQQLRREQEERREQL---LKREEEKRLEQERREQRLKREQEERRD---QL 578
+ S Q L E E R QL LK +K L ++ + EE+ QL
Sbjct: 3010 SPETSASPDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQL 3069
Query: 579 LKREEERRQQR------------LKREQEERLEQRLKREEVERLEQEERREQRLKREEPE 626
+ R+ + L+++ +E L + QE+ R + +PE
Sbjct: 3070 CDTSQSLRENQQHYGDLLNHCAVLEKQVQELQAGPLNIDVAPGAPQEKNGVHR--KSDPE 3127
Query: 627 EERRQQLLKSEEQEE---RRQQ--QLRREQQERREQRLKREEEEERLEQRLKR-EHEE 678
E R Q SE Q++ RQ+ +LR+ +E R+QR+ E E++++R EH E
Sbjct: 3128 ELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAAENALSVAEEQIRRLEHSE 3185
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 219 bits (559), Expect = 2e-56
Identities = 140/526 (26%), Positives = 271/526 (51%), Gaps = 32/526 (6%)
Query: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325
Q ++ ++ + + + +E RRE+++ E++ R R RR++++ R++ R Q+
Sbjct: 44 QAHKDADGDDRERNRQKERERRREKRQTERETDRKRE----RRREKDRHRKRDRHRERQR 99
Query: 326 ERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR 385
+R +++E + +++ R++E+ R +Q RE+E ER ++ R Q + +RE++ +R+ + R
Sbjct: 100 DREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKER 159
Query: 386 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ 445
E+Q RE+Q + E+ ++E++ + +Q RRE++ +RE++ + E+RH ++ + RE+
Sbjct: 160 ERQTDRERQRQTERNRQKEREREKNRQERRERERQREKE---NKTEDRHSERGRERERER 216
Query: 446 RLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQ-QERRE 504
+ E E +R + + + E+ER KQ + E ER + E E R++ ++RR+
Sbjct: 217 ETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQ 276
Query: 505 QQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERRE 564
++ R+ + +R++R +R E ER ++R +RE+E RE+ KRE E+ E+ER
Sbjct: 277 KERERQTDRKRQRRTERDRETERKRER-------QRERERERERNRKRERERERERERER 329
Query: 565 QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE 624
QR E RD+ +RE +R++Q + R R R + ER + ER R E
Sbjct: 330 QR-----ETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARE 384
Query: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE 684
EE R + ++++ R++Q +++ +RE +RE E++R +R RE ER +Q+
Sbjct: 385 REERERD---RDRDRQKERERQTEKDRDGQRETEKQREREKDRESER-GRERGREREKQK 440
Query: 685 LAEEEQEQARERIKSRIPKWQ--WQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRR 742
E ++E+ +R R K + AR V S P + R + E +
Sbjct: 441 GRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAA 500
Query: 743 ESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP 788
+ W +A R + +R W+ +RG+ RP
Sbjct: 501 STRFPWGRPAKASRGRVAGRRR------WEPRLGEKRGQGGEGRRP 540
Score = 219 bits (558), Expect = 2e-56
Identities = 158/539 (29%), Positives = 287/539 (53%), Gaps = 43/539 (7%)
Query: 219 RRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
RR G +E ++R Q + +++E +++ R+ E++ E E R+RE + E+++
Sbjct: 29 RRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRH 88
Query: 279 RKLER-QELRRERQEE-EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE 336
RK +R +E +R+R++E E+Q R R Q+ + + ++ RE++ ER ++ R Q + +RE
Sbjct: 89 RKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRE 148
Query: 337 QQLRREQEERREQQLRRE-QEEERREQQLRREQE---EERREQQLRREQQLRREQQLRRE 392
++ +R+ E+ RE+Q RE Q + R +Q RE+E +ERRE++ +RE++ + E + E
Sbjct: 149 RERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR-HSE 207
Query: 393 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQE 452
+ RE++ E + R++Q RE+ +R+ + RE++ ER + R++ +RE++
Sbjct: 208 RGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERD 267
Query: 453 ERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE 512
RD +R++E ER +R+++ +RD+E ER+ E +RE++ RE+ +RE+E
Sbjct: 268 RDRDRDRRQKERERQTDRKRQRRTERDRETERKR-------ERQRERERERERNRKRERE 320
Query: 513 ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQE 572
RE+ +RQ E E R++E+ RE+ KR+ E E+ R+ R R Q
Sbjct: 321 RERERERERQRETE-------------RDREKERERKRKRQTEMDRERNRQTGREGRRQA 367
Query: 573 ERRDQLLKREEER-RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQ 631
ER + RE ER RQ +RE+ ER R +++E ER +++R QR E E+++
Sbjct: 368 ERERE---RERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQR------ETEKQR 418
Query: 632 QLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQE 691
+ K E E R++ RE+Q+ RE+ +R+ + + QR KR A
Sbjct: 419 EREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQR-KRSTLYVNPPPRTARSGVV 477
Query: 692 QARERIKSRIPKWQWQLESEADARQSKVYSRPRKQE-----GQRRRQEQEEKRRRRESE 745
Q+ +R +W+ E A + RP K G+RR + + ++R + E
Sbjct: 478 QSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGE 536
Score = 219 bits (557), Expect = 3e-56
Identities = 133/438 (30%), Positives = 256/438 (58%), Gaps = 19/438 (4%)
Query: 207 EEQLRRRELLELRRKG----REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQE 262
+E RRR L + + RE +Q+ RER+ Q E E + RKRE R+E+++ ++
Sbjct: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETD-RKRER--RREKDRHRK 90
Query: 263 EEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERR 322
+ R+R+ E+E+ R+ +R+ R+RQ E+++ ++ RE++ R+ E R Q + +R
Sbjct: 91 RDRHRERQRDREKERERQTDRE---RDRQREKERNRQKERERETEREGERGRDRQTDGQR 147
Query: 323 EQQERREQQEERREQQLR-REQEERREQQLRREQEEERREQQLR-REQEEERREQQLRRE 380
E++ +R+ ++ER Q R R+++ R +Q RE+E+ R+E++ R R++E+E + + E
Sbjct: 148 ERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSE 207
Query: 381 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQ 440
+ RE++ E + R++Q RE+ +R+ + RE+Q RE+ RE E ++ ++
Sbjct: 208 RGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERD 267
Query: 441 ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQ 500
R++ ++++ ER+ KR+ TER + RK++ +R++E ER ER K E E RE++
Sbjct: 268 RDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER-ERNRKRERERERERE 326
Query: 501 ERREQQLRREQEERREQRLKRQEEEERLQQRL-----RSEQQLRREQEERREQLLKREEE 555
R+++ R++E+ RE++ KRQ E +R + R R + + RE+E R++ RE E
Sbjct: 327 RERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARERE 386
Query: 556 KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEER 615
+R R+++ +RE++ +D+ +RE E++++R K + ER +R RE ++ +E
Sbjct: 387 ERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRER-GREREKQKGRERD 445
Query: 616 REQRLKREEPEEERRQQL 633
RE++ R+ + +R L
Sbjct: 446 RERQTDRQAGRQRKRSTL 463
Score = 216 bits (550), Expect = 2e-55
Identities = 151/502 (30%), Positives = 263/502 (52%), Gaps = 41/502 (8%)
Query: 308 RKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRRE 367
R +++ER ++E+R+ ++E ++E RRE+ R+++ RE+Q RE+E ER+ + R
Sbjct: 56 RNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDR 115
Query: 368 QEEERREQQLRREQQLRREQQLRREQQL--RREQQLRREQQLRREQQLRREQQLRREQQL 425
Q E+ R +Q RE++ RE + R++Q +RE++ +R+ + RE+Q RE R++Q
Sbjct: 116 QREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRE----RQRQT 171
Query: 426 RREQEEERHEQKHEQERREQRLKREQEERRD------WLKREEETERHEQERRKQQLKRD 479
R +++ER +K+ QERRE+ +RE+E + + +RE E E + RK+Q R+
Sbjct: 172 ERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE 231
Query: 480 QEEER---RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQ 536
++ +R RER + E E E++ R+++ RE++ R+ R +RQ+E ER R R
Sbjct: 232 RDRQRKTEREREKQAERERASERETERDKERERERDRDRD-RDRRQKERERQTDRKR--- 287
Query: 537 QLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEE 596
+R E RE KRE ++ E+ER R KRE+E R++ +RE +R +R + ++ E
Sbjct: 288 --QRRTERDRETERKRERQRERERERERNR-KRERERERER--ERERQRETERDREKERE 342
Query: 597 RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE 656
R +R + ER Q R +R E E ER + + E+EER + + R Q+ER
Sbjct: 343 RKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERER 402
Query: 657 QRLKREEEEERLEQRLKRE--HEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADA 714
Q K + + E++ +RE E ER + E E+++ RER + R Q ++
Sbjct: 403 QTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRER----QTDRQAGRQR 458
Query: 715 RQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAE 774
++S +Y P + + + + R R ++W + E+ + + W
Sbjct: 459 KRSTLYVNPPPRTARSGVVQSDPNRPTR--GIRW-------KSSPEDPKAASTRFPWGRP 509
Query: 775 EKSERGR--QRLSARPPLREQR 794
K+ RGR R P L E+R
Sbjct: 510 AKASRGRVAGRRRWEPRLGEKR 531
Score = 212 bits (539), Expect = 3e-54
Identities = 133/425 (31%), Positives = 248/425 (58%), Gaps = 24/425 (5%)
Query: 125 RDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQR---RDEELWRQRQEWQ 181
R+RQ E E RRR+KRQ ERE E+ +++R +RDR R RD E R+RQ +
Sbjct: 56 RNRQKERE---RRREKRQT-ERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDR 111
Query: 182 EREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEE 241
ER+ +R +E Q + ETE + + R+ + G+ E+++QR ++R Q +
Sbjct: 112 ERDRQREKERNRQKERERETEREGERGRDRQTD-------GQRERERQRDAEKERERQTD 164
Query: 242 EEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLR 301
E++ R+ E +KE E+ + + +R+RE Q E+E + E RER+ E + +
Sbjct: 165 RERQ-RQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETE 223
Query: 302 REQQLRRKQEEERR-EQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR 360
R++Q R+++ +R+ E++ E++ ++ER ++E R+++ RE++ R++ RR++E ER+
Sbjct: 224 RKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRD-RRQKERERQ 282
Query: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
+ R+ + E RE + +RE+Q RE++ R ++ RE++ RE++ +RE + RE++
Sbjct: 283 TDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERE 342
Query: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480
R+++ + E + ER+ Q + RR+ +RE+E RD R+ ER E+ER + RD+
Sbjct: 343 RKRKRQTEMDRERNRQTGREGRRQAERERERERERD---RQSAREREERERDRD---RDR 396
Query: 481 EEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRR 540
++E RER + + + +RE +++RE++ RE E RE+ +R++++ R + R R +
Sbjct: 397 QKE-RERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAG 455
Query: 541 EQEER 545
Q +R
Sbjct: 456 RQRKR 460
Score = 211 bits (536), Expect = 7e-54
Identities = 127/459 (27%), Positives = 257/459 (55%), Gaps = 35/459 (7%)
Query: 115 QEEDQRR-FEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE-KQERLEQRDRQRRDEE 172
QE +RR + + + +R RQK +E+ RE + E +++ K+ER ++DR R+ +
Sbjct: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRD- 92
Query: 173 LWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRE 232
R R+ ++RE+ R E D E+ R+RE R+K RE + ++ E
Sbjct: 93 --RHRERQRDREKER--------------ERQTDRERDRQREKERNRQKERERETEREGE 136
Query: 233 R-QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ 291
R +DR + E+E R+ KE E+ + E QRQ E ++E+ R+ RQE R +
Sbjct: 137 RGRDRQTDGQRERE---RQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERER 193
Query: 292 EEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQL 351
+ E++ + R + R++E ER + E R++Q RE+ +R+ ++ R +Q ER
Sbjct: 194 QREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253
Query: 352 RREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 411
R + ++ RE++ R+++ +RR+++ R+ +R+++ R+++ R+++ +RE++ RE+
Sbjct: 254 RETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERER 313
Query: 412 QLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDW---LKREEETERHE 468
+RE++ RE++ R++E ER +K + +R+++ + ++E R +R+ E ER
Sbjct: 314 NRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERER 373
Query: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 528
+ R +Q R++EE R+R R++Q+ RE+Q ++++ +RE +R+ E++R
Sbjct: 374 ERERDRQSAREREERERDR--------DRDRQKERERQTEKDRDGQRETEKQREREKDRE 425
Query: 529 QQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL 567
+R R E+ RE+++ RE+ +R+ +++ ++R+ L
Sbjct: 426 SERGR-ERGREREKQKGRERDRERQTDRQAGRQRKRSTL 463
Score = 208 bits (529), Expect = 5e-53
Identities = 128/447 (28%), Positives = 256/447 (57%), Gaps = 23/447 (5%)
Query: 94 GLDEEKRARCDG---KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAE 150
G E R R G K++ DR + + R R+++ E R+R++R+E++R
Sbjct: 32 GSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKR 91
Query: 151 GEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQL 210
+ +++R ++R+RQ D E RQR++ + R++ R E + + +G + + E+
Sbjct: 92 DRHRERQRDREKERERQT-DRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERE 150
Query: 211 RRRELLELRRK--GREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQ 268
R+R+ + R + RE ++Q R RQ +E+ +E R+RE R++E K ++ +R
Sbjct: 151 RQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQ-REKENKTEDRHSERG 209
Query: 269 RELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERR 328
RE + E E + ER+ + +R+ + Q++ RE+Q R++ ER ++++ RE++ R
Sbjct: 210 RERERERETETETERKR-QTDRERDRQRKTEREREKQAERERASERETERDKERERERDR 268
Query: 329 EQQEERREQQLRREQEERREQQLRREQEEER-REQQLRREQEEERREQQLRREQQLRREQ 387
++ +RR+++ R+ + +R+++ R++E ER RE+Q RE+E ER +RE++ RE+
Sbjct: 269 DRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNR---KRERERERER 325
Query: 388 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL 447
+ R+++ R+++ RE++ +R+ ++ RE+ + ++ RR+ E ER E++ E++R+ R
Sbjct: 326 ERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERER-ERERERDRQSARE 384
Query: 448 KREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQL 507
+ E+E RD R+ + ER Q + + +R+ E++R E E+ RE + RE+
Sbjct: 385 REERERDRD---RDRQKERERQTEKDRDGQRETEKQR-------EREKDRESERGRERGR 434
Query: 508 RREQEERREQRLKRQEEEERLQQRLRS 534
RE+++ RE+ +RQ + + +QR RS
Sbjct: 435 EREKQKGRERDRERQTDRQAGRQRKRS 461
Score = 206 bits (523), Expect = 2e-52
Identities = 141/498 (28%), Positives = 269/498 (54%), Gaps = 58/498 (11%)
Query: 892 KPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKR 951
+P QE R+ L + ++ ++RE+ R++E+ER+ RE+ Q ++E + R++
Sbjct: 30 RPGSQESPRRRG--LGQAHKDADGDDRERNRQKERERR-REKRQTERETD------RKRE 80
Query: 952 RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKR 1011
RR+E++R ++D+ E ++ R +ERE++ E + Q+E+E+ ++ERE+
Sbjct: 81 RRREKDRHRKRDRH----------RERQRDREKERERQTDRERDRQREKERNRQKERERE 130
Query: 1012 RRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETR 1071
+E ER ++ + Q+E E+ E+E+ R +RERQ + E Q+E E+ E+ +
Sbjct: 131 TEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERER----EKNRQ 186
Query: 1072 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131
R+E ERQ KE + + E+ R +ERER+ E E +++ ++ ER+++
Sbjct: 187 ERRERERQREKENKTEDRHS-------ERGRERERERETETETERKRQTDR----ERDRQ 235
Query: 1132 RRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKR 1191
R+ E ER+ + E E E E +E E+ R ++ +R R++E +Q + + R + R
Sbjct: 236 RKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDR 295
Query: 1192 RQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFR 1251
ER+R+ + E E +R++ ++R R+ ++ + + Q E E++ K RE ++ R
Sbjct: 296 ETERKRERQRERERERERNRKRERERERERERERQRETERDRE--------KERERKRKR 347
Query: 1252 QLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRD 1311
Q E + R+RQ+ G + R E+ER R ++RDR + EREE++ + RD
Sbjct: 348 QTEMDRERNRQT--------GREGRRQAERERERERERDR----QSAREREERERDRDRD 395
Query: 1312 RKSQEEKQLLRE---ERE-EKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEEL 1367
R+ + E+Q ++ +RE EK+R +E DR+ + +ERE+Q R ++R+R+ +
Sbjct: 396 RQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAG 455
Query: 1368 RHQEQGRKFLEEEQRLRR 1385
R +++ ++ R R
Sbjct: 456 RQRKRSTLYVNPPPRTAR 473
Score = 203 bits (516), Expect = 2e-51
Identities = 136/476 (28%), Positives = 260/476 (54%), Gaps = 31/476 (6%)
Query: 334 RREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQ 393
RR + R Q ++ + + RE+ ++E+E R ++Q RE +RE+
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRER------ 81
Query: 394 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEE 453
RRE+ R++ RE+Q RE++ RE+Q RE++ +R ++++ Q+ RE+ +RE E
Sbjct: 82 --RREKDRHRKRDRHRERQRDREKE--RERQTDRERDRQREKERNRQKERERETEREGER 137
Query: 454 RRDWL---KREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRRE 510
RD +RE E +R ++ R++Q R+++ + ER + E E + +QERRE++ +RE
Sbjct: 138 GRDRQTDGQRERERQRDAEKERERQTDRERQRQT-ERNRQKEREREKNRQERRERERQRE 196
Query: 511 QEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLK--REEEKRLEQERREQR-L 567
+E + E R + E ++ +E + +R+ + R++ K RE EK+ E+ER +R
Sbjct: 197 KENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERET 256
Query: 568 KREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKRE-EPE 626
+R++E R++ R+ +RRQ+ +R+ + + ++R +R+ E E +RE++ +RE E E
Sbjct: 257 ERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDR----ETERKRERQRERERERE 312
Query: 627 EERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELA 686
R+++ + E+E RQ++ R++++ RE++ KR+ E +R +R ++ E RR+ E
Sbjct: 313 RNRKRERERERERERERQRETERDREKERERKRKRQTEMDR--ERNRQTGREGRRQAE-R 369
Query: 687 EEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQ-EQEEKRRRRESE 745
E E+E+ R+R +R + E E D + + R R+ E R Q E E++R R +
Sbjct: 370 ERERERERDRQSARERE-----ERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDR 424
Query: 746 LQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAE 801
+ ER +++++ + RD Q + +R R L PP R R ++++
Sbjct: 425 ESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSD 480
Score = 201 bits (512), Expect = 4e-51
Identities = 136/477 (28%), Positives = 265/477 (55%), Gaps = 45/477 (9%)
Query: 952 RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKR 1011
RR+ ++ + + L Q + G++ E+ R++ERE++ RE+ + ++E ++ REK
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERR-REKRQTERETDRKRERRREKD 86
Query: 1012 RRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETR 1071
R ++ +R ++ + ++E E+ ER+++R +ER RQ E E ++E E+ G +R+T
Sbjct: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGER--GRDRQTD 144
Query: 1072 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131
++E ERQ E+E +++ ++ + + E+ R++ERER+ + +E ++ E Q +E + +
Sbjct: 145 GQRERERQRDAEKERERQTDRERQRQTERNRQKERERE-KNRQERRERERQREKENKTED 203
Query: 1132 RRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKR 1191
R E R+ E E + E E+ + + E+ R+++ ER+ R
Sbjct: 204 RHSERGRERERERETETETERKRQTDRERDRQRKTERE---------------------R 242
Query: 1192 RQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFR 1251
++ ER+ E E +R K ++R RD D+ D + Q E E++ D K R+ R
Sbjct: 243 EKQAERERASERETERDKERERERDRDRDRDRR-QKERERQT---DRK-----RQRRTER 293
Query: 1252 QLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRD 1311
E + R+RQ +++ + ++ER+RE+ER R +QR E + +RE+++E KR+
Sbjct: 294 DRETERKRERQRERERERERNRKRERERERERERERQR------ETERDREKERERKRK- 346
Query: 1312 RKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQE 1371
R+++ +++ R+ E RR+ E +R+ RE E+ Q E+ R ++RDR ++E R E
Sbjct: 347 RQTEMDRERNRQTGREGRRQAERERE-RERERDRQSAREREERERDRDRDRQKERERQTE 405
Query: 1372 QGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQER 1428
+ R E ++ R +E++R+ E + R +ERE+Q ++RDR+ R+ ++Q RQ +
Sbjct: 406 KDRDGQRETEKQREREKDRE--SERGRERGREREKQKGRERDRE-RQTDRQAGRQRK 459
Score = 201 bits (512), Expect = 4e-51
Identities = 143/492 (29%), Positives = 252/492 (51%), Gaps = 56/492 (11%)
Query: 355 QEEERREQ--QLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 412
QE RR Q ++ + + RE+ ++E++ RRE++ Q RE +RE+ RRE+
Sbjct: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKR-----QTERETDRKRER--RREKD 86
Query: 413 LRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR 472
R++ RE+Q RE+E ER + +RE+ R++E RE ETER + R
Sbjct: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKE-------RERETEREGERGR 139
Query: 473 KQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRL 532
+Q +E ER+ E+E R+ R++Q R +++ RE+ RQE ER +QR
Sbjct: 140 DRQTDGQRERERQR---DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQRE 196
Query: 533 RSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592
+ + R E RE+ +RE E E ER KR+ + RD+ K E ER +Q +
Sbjct: 197 KENKTEDRHSERGRER--ERERETETETER-----KRQTDRERDRQRKTEREREKQAERE 249
Query: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652
ER +R K E ER +++ R++R K E + +R++Q ++E R+++ +RE++
Sbjct: 250 RASERETERDKERERER-DRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERE 308
Query: 653 ERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEA 712
RE+ KRE E RE E ER Q E ++E+ RER + R ++E
Sbjct: 309 RERERNRKRERE---------RERERERERQRETERDREKERERKRKR--------QTEM 351
Query: 713 DARQSKVYSRPRKQEGQRRRQEQEEKRRR--RESELQWQEEERAHRQQQEEEQRRDFTWQ 770
D +++ R +++ +R R+ + E+ R+ RE E + ++ +R ++++E + +D Q
Sbjct: 352 DRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQ 411
Query: 771 WQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKE 830
+ E++ ER + R S R RER E+++ RE+ + E++ R+ R+R++
Sbjct: 412 RETEKQREREKDRESER-----GRERGREREKQKGRER-----DRERQTDRQAGRQRKRS 461
Query: 831 LQFLEEEEQLQR 842
++ + R
Sbjct: 462 TLYVNPPPRTAR 473
Score = 201 bits (510), Expect = 8e-51
Identities = 143/483 (29%), Positives = 260/483 (53%), Gaps = 53/483 (10%)
Query: 730 RRRQEQEEKRRRR---ESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA 786
RRR +E RRR ++ ++R +Q+E E+RR+ + Q E +++R R+R
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRRE---KRQTERETDRKRER--- 81
Query: 787 RPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERA 846
R +++R R +R + QR +E E++ R + R+REKE +E E+ RE
Sbjct: 82 ----RREKDRH-RKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGE 136
Query: 847 QQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLL 906
+ + DG Q ++ER+R E+ R++ + +R+R+R T E+
Sbjct: 137 RGRDRQTDG-QRERERQRDAEKERER------QTDRERQRQT-------------ERNRQ 176
Query: 907 QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL 966
+E E E R+ER +R RQ ++ E+ ++ E+ ERE ER+RQ +++
Sbjct: 177 KEREREKNRQERRERERQREKENKTEDRHSERGRER--ERERETETETERKRQTDRERDR 234
Query: 967 QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
Q+K E+ ++ E+ R ERE + +E E +++ ++ R+ R+K R ++ +R+ +++ E
Sbjct: 235 QRKTEREREKQAERERASERETERDKERERERDRDRD-RDRRQKERERQTDRKRQRRTER 293
Query: 1027 QQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEEL 1086
+E E+ + ER++ R +ERER + E E ++E E+ +RET R +E ER+ +++ +
Sbjct: 294 DRETER--KRERQRERERERERNRKRERERERERER--ERQRETERDREKERERKRKRQT 349
Query: 1087 QQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEV 1146
+ + E+ + E RR+ ERER+ E + Q E REERE+ R +R ++E E
Sbjct: 350 EMDRERNRQTGREGRRQAERERERERERDRQSARE---REERERDR----DRDRQKERER 402
Query: 1147 QQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQ 1206
Q E+++ + E EK+R +E +R+ E +E RE+Q+ R ++RERQ + Q
Sbjct: 403 QTEKDRDGQRETEKQREREKDRESERGRERGRE-----REKQKGRERDRERQTDRQAGRQ 457
Query: 1207 RQK 1209
R++
Sbjct: 458 RKR 460
Score = 200 bits (509), Expect = 1e-50
Identities = 135/484 (27%), Positives = 250/484 (51%), Gaps = 51/484 (10%)
Query: 411 QQLRREQQLRREQQLRREQEEERHEQKHEQERREQR-LKREQEERRDWLKREEETERHEQ 469
Q+ R + L + + + ER+ QK + RRE+R +RE + +R+ R E +RH +
Sbjct: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRE---RRREKDRHRK 90
Query: 470 ERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQ 529
R ++ +RD+E+ER ER E + +RE++ R+++ RE E E+ RQ + +R +
Sbjct: 91 RDRHRERQRDREKER-ERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRER 149
Query: 530 QRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQR 589
+R R ++ R Q +R Q R+ E+ ++ER ++ ++E+ ER Q + +E + + R
Sbjct: 150 ERQRDAEKERERQTDRERQ---RQTERNRQKEREREKNRQERRERERQ--REKENKTEDR 204
Query: 590 LKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRR 649
ER +R E ER Q +R R ++ E E E++ + ++ E+E R ++ R
Sbjct: 205 HSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERER 264
Query: 650 EQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLE 709
E+ R++ +++E E + +++ +R E +R + E ++E+ RER ++R K + + E
Sbjct: 265 ERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNR--KRERERE 322
Query: 710 SEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTW 769
E + + + R R++E +R+R+ Q E R R ++ R R+Q E E+ R
Sbjct: 323 RERERERQRETERDREKERERKRKRQTEMDRERN-----RQTGREGRRQAERERER---- 373
Query: 770 QWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREK 829
ER R R SAR RE+RER R +RQ+ +R ++ + ++ ++REREK
Sbjct: 374 --------ERERDRQSARE--REERERD-RDRDRQKERERQTEKDRDGQRETEKQREREK 422
Query: 830 ELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTL 889
+ +E E G + +ER + + + RD++ + + R+R+R TL
Sbjct: 423 D-------------------RESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTL 463
Query: 890 YAKP 893
Y P
Sbjct: 464 YVNP 467
Score = 199 bits (505), Expect = 3e-50
Identities = 133/445 (29%), Positives = 240/445 (53%), Gaps = 23/445 (5%)
Query: 838 EQLQRRERAQQLQEEEDGLQEDQERRRSQE-QRRDQKWRWQLEEERKRRRHTLYAKPALQ 896
++ RR Q ++ DG +D+ER R +E +RR +K + + E +RKR R + +
Sbjct: 34 QESPRRRGLGQAHKDADG--DDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKR 91
Query: 897 EQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQER 956
++ R+ Q+ ++E E ER+++R +E+ RQ E + ++E E+ + + +R +ER
Sbjct: 92 DRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERER 151
Query: 957 ERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQ-QEEEQLLREEREKRRRQE 1015
+R K+++ Q E+ E +++ +EREK +E E + Q E++ E+R R +E
Sbjct: 152 QRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRE 211
Query: 1016 WERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE 1075
ER+ ++ E + E ++ ER+++R ERER+ + E E E E +ERE R ++
Sbjct: 212 RERE--RETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRD 269
Query: 1076 LERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135
+R R++E +Q + + ++RR ER+R+ + E Q+E E+ ERE+ R++E
Sbjct: 270 RDRDRRQKERERQTDRK-------RQRRTERDRETERKRERQRERER----ERERNRKRE 318
Query: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
ER+ E E Q+E E+ +E E++R+++ E RE E + E + +R +ER
Sbjct: 319 RERERERERERQRETERDREKERERKRKRQTEMD-RERNRQTGREGRRQAERERERERER 377
Query: 1196 ERQ---YREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQ 1252
+RQ REE E R + +Q+ R+ D Q E EK+ ++ +GRE + R+
Sbjct: 378 DRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRERE 437
Query: 1253 LEDSQLRDRQSQQDLQHLLGEQQER 1277
+ + RDR+ Q D Q G Q++R
Sbjct: 438 KQKGRERDRERQTDRQ--AGRQRKR 460
Score = 198 bits (504), Expect = 4e-50
Identities = 133/447 (29%), Positives = 250/447 (55%), Gaps = 18/447 (4%)
Query: 1012 RRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETR 1071
RR+ ++ ++ L Q + ++RE+ R +ERER+ RE+ + ++E ++ RE
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERR-REKRQTERETDRKRERRREKD 86
Query: 1072 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131
R ++ +R ++ + ++E E+ E +++R +ER RQ E E ++E E+ + + +
Sbjct: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQ 146
Query: 1132 RRQELERQYREEEEVQQEEEQLLREE--PEKRRRQELERQYREEEELQQEEEQLLREEQE 1189
R +E +R +E E Q + E+ + E +K R +E RQ R E E Q+E+E +
Sbjct: 147 RERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS 206
Query: 1190 KRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQ 1249
+R +ERER+ E E +R+++ R RD ++++ + + + E+E A K RE E+
Sbjct: 207 ERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERER 266
Query: 1250 FRQLE-DSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAK 1308
R + D + ++R+ Q D + + ERDRE ER+R +QR+R E +RE ++E +
Sbjct: 267 DRDRDRDRRQKERERQTDRKR--QRRTERDRETERKRERQRERERERERNRKRERERERE 324
Query: 1309 RRDRKSQEEKQLLREEREEKRRRQ-----ETDRKFREEEQLLQEREEQPLRRQERDRK-F 1362
R + +E ++ +ERE KR+RQ E +R+ E + ERE + R +ERDR+
Sbjct: 325 RERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERE--RERERDRQSA 382
Query: 1363 REEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQ 1422
RE E R +++ R +++R R+ E++R +E ++ R +E++++ + R+R RE E+Q
Sbjct: 383 REREERERDRDRD--RQKERERQTEKDRDGQRETEKQREREKDRESERGRERG-REREKQ 439
Query: 1423 LSRQERDRKFREEEQQVRRQERERKFL 1449
R ERDR+ + + Q R+++R ++
Sbjct: 440 KGR-ERDRERQTDRQAGRQRKRSTLYV 465
Score = 196 bits (497), Expect = 2e-49
Identities = 139/449 (30%), Positives = 246/449 (54%), Gaps = 33/449 (7%)
Query: 1279 REQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQL--LREEREEKRRRQETDR 1336
+E RRR + + + ER QKE +RR K Q E++ RE R EK R ++ DR
Sbjct: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR 93
Query: 1337 KFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEE 1396
+ +ERE Q R ERDR+ +E R +E+ R+ E +R R +R+ +E
Sbjct: 94 HRERQRDREKERERQTDR--ERDRQREKERNRQKERERETEREGERGR--DRQTDGQRER 149
Query: 1397 QQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLR 1456
++ R E+E++ + DR+R+ + E + +ER++ +E ++ R++E+E K + +
Sbjct: 150 ERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERG 209
Query: 1457 QERHRKFREE------EQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRS 1510
+ER R+ E Q +ER+ Q+ +ER+++ E R ERD++ + R
Sbjct: 210 RERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRD 269
Query: 1511 QEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQ 1570
++ +R+ E E+Q R+ RQR+ ++ + R++ER ++R ++R+R + E + +ERE +
Sbjct: 270 RDRDRRQKERERQTDRK-RQRRTERDRETERKRERQRERERERERNRKRERERERERERE 328
Query: 1571 QLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQE 1630
+ ERDR+ E ++ R+ E +R E +Q R EG++Q +ER+R+ D Q +E
Sbjct: 329 RQRETERDREKERERKRKRQTEMDR---ERNRQTGR-EGRRQAERERERERERDRQSARE 384
Query: 1631 REEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD 1690
REE++ ++RDR R++ERE+Q DRD + E+Q +E + + R +ER
Sbjct: 385 REERE---RDRDRD--------RQKERERQTEKDRDGQRETEKQREREKDRESERGRERG 433
Query: 1691 RKFREEEQQLRRQERERKFLQEEQQLRRQ 1719
R+ E+Q+ R ++RER Q ++Q RQ
Sbjct: 434 RE--REKQKGRERDRER---QTDRQAGRQ 457
Score = 196 bits (497), Expect = 2e-49
Identities = 131/432 (30%), Positives = 244/432 (56%), Gaps = 30/432 (6%)
Query: 89 LGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLE-EEPGQRRRQKRQEQERE 147
LGQA K A D +E RQ+E +RR E R + E + +RRR+K + ++R+
Sbjct: 42 LGQA-----HKDADGDDRER----NRQKERERRREKRQTERETDRKRERRREKDRHRKRD 92
Query: 148 LAEGEEQSEKQERLEQRDRQR-RDEELWRQRQEWQERE-ERRAE-----------EEQLQ 194
++ ++ER Q DR+R R E R RQ+ +ERE ER E E + Q
Sbjct: 93 RHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQ 152
Query: 195 SCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLR 254
E E D E+ R+ E + + RE+ +Q+RRER+ R ++E + E R E
Sbjct: 153 RDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERE-RQREKENKTEDRHSERGRE 211
Query: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314
+E E+ E E +R+R+ E ++ RK ER+ RE+Q E ++ E+ R++E +R
Sbjct: 212 RERERETETETERKRQTDRERDRQRKTERE---REKQAERERASERETERDKERERERDR 268
Query: 315 REQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEER-REQQLRREQEEER- 372
++ R++++ER+ ++ +R + RE E +RE+Q RE+E ER R+++ RE+E ER
Sbjct: 269 DRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERE 328
Query: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEE- 431
R+++ R+++ RE++ +R+ ++ RE+ + ++ RR+ + RE++ R++Q RE+EE
Sbjct: 329 RQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREER 388
Query: 432 ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKL 491
ER + Q+ RE++ +++++ +R+ K+ E + E ER +++ + ++++ RER +
Sbjct: 389 ERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRER 448
Query: 492 EEEERREQQERR 503
+ + + +Q +R
Sbjct: 449 QTDRQAGRQRKR 460
Score = 192 bits (489), Expect = 2e-48
Identities = 132/458 (28%), Positives = 245/458 (53%), Gaps = 41/458 (8%)
Query: 1056 LQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEE 1115
L Q + G++RE R++E ER+ R++ + ++E ++ EK R ++R+R + +
Sbjct: 42 LGQAHKDADGDDRERNRQKERERR-REKRQTERETDRKRERRREKDRHRKRDRHRERQRD 100
Query: 1116 LQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175
++E E+ ER+++R +E RQ E E ++E E+ + + +R +E +R +E E
Sbjct: 101 REKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERE 160
Query: 1176 LQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV 1235
Q + E+ +R+ ER RQ E E RQ+R++R R EKEN
Sbjct: 161 RQTDRER-------QRQTERNRQKEREREKNRQERRERERQR------------EKENKT 201
Query: 1236 RDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE 1295
D +GRE E+ R+ E R RQ+ ++ ++R R+ ER R +Q +R
Sbjct: 202 EDRHSE-RGRERERERETETETERKRQTDRE--------RDRQRKTEREREKQAERERAS 252
Query: 1296 EEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRR 1355
E + ER++++E + RDR +++ ER+ R+RQ + RE E ++RE Q R
Sbjct: 253 ERETERDKERE-RERDRDRDRDRRQKERERQTDRKRQRRTERDRETE---RKRERQRERE 308
Query: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRK 1415
+ER+R + E R +E+ R+ E +R R +ERERK ++ + +RE+ + R+ +
Sbjct: 309 RERERNRKRERERERERERERQRETERDREKERERKRKRQTE----MDRERNRQTGREGR 364
Query: 1416 FREEEQQLSRQERDRK-FREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQERE 1474
+ E ++ +ERDR+ RE E++ R ++R+R ++E++ + E+ R + E + +ERE
Sbjct: 365 RQAERERERERERDRQSAREREERERDRDRDR---QKERERQTEKDRDGQRETEKQRERE 421
Query: 1475 EQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQE 1512
+ + + R+R E+Q+ R ++R+R+ Q R ++
Sbjct: 422 KDRESERGRERGREREKQKGRERDRERQTDRQAGRQRK 459
Score = 192 bits (487), Expect = 3e-48
Identities = 129/469 (27%), Positives = 243/469 (51%), Gaps = 44/469 (9%)
Query: 611 EQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQ 670
E RR ++ + + R++ + E + R ++Q RE +RE+R RE++ R
Sbjct: 35 ESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERR--REKDRHR--- 89
Query: 671 RLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQR 730
KR+ ER+ E E++ RER + R + Q E E + + R R+ +GQR
Sbjct: 90 --KRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQR 147
Query: 731 RRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPL 790
R+ Q + + RE + + + + R +Q+E +R +E+ ER RQR
Sbjct: 148 ERERQRDAEKERERQTDRERQRQTERNRQKEREREK-----NRQERRERERQR------- 195
Query: 791 REQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQ 850
++ + + R ER + +R E E E++R+ RER+++ + E E+ RERA + +
Sbjct: 196 EKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERE 255
Query: 851 EEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEE 910
E D +++ER R +++ RD++ ++ER+R+ RK Q+ + +
Sbjct: 256 TERD---KERERERDRDRDRDRR-----QKERERQTD------------RKRQRRTERDR 295
Query: 911 EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKE 970
E ++ ER++ R +E+ER + E + ++E E+ + E E+ R +ERER+ ++ ++ ++
Sbjct: 296 ETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRER 355
Query: 971 EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEE 1030
+ G E ++ +ERE++ + + +E E+ R +R++ R++E ERQ K + Q+E
Sbjct: 356 NRQTGREGRRQAERERERERERDRQSAREREERER-DRDRDRQKERERQTEKDRDGQRET 414
Query: 1031 EQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQ 1079
E+ + EREK R ER R+ E E Q+ E+ ER+T R+ +R+
Sbjct: 415 EK--QREREKDRESERGRERGREREKQKGRER--DRERQTDRQAGRQRK 459
Score = 191 bits (485), Expect = 6e-48
Identities = 151/530 (28%), Positives = 264/530 (49%), Gaps = 100/530 (18%)
Query: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIP 702
R++ +E RR ++ + +R +++ E RRE+ E E ++ RER + +
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREK-- 85
Query: 703 KWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEE 762
R RK++ R RQ EK R R+++ + + R +Q+E
Sbjct: 86 ------------------DRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKER 127
Query: 763 QRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRR 822
+R + E + ERGR R + + +RERQ AE+ ++R+ ++E++R+
Sbjct: 128 ER-------ETEREGERGRDRQTDG---QRERERQRDAEKERERQT-------DRERQRQ 170
Query: 823 QRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEER 882
R R+KE + E+ + +RRER +Q E++ ED+ R +E+ R++ + E E
Sbjct: 171 TERNRQKERE--REKNRQERRERERQ--REKENKTEDRHSERGRERERER----ETETET 222
Query: 883 KRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQ 942
+R+R T ER+++R+ E+ER+ + E + E E
Sbjct: 223 ERKRQT--------------------------DRERDRQRKTEREREKQAERERASERET 256
Query: 943 LLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQ 1002
ER+K R +ER+R +D++ +++E Q + +++RR ER+++ + E Q+E E+
Sbjct: 257 ----ERDKERERERDRDRDRDRRQKERERQ---TDRKRQRRTERDRETERKRERQRERER 309
Query: 1003 LLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQ 1062
ERE+ R++E ER+ ++ E Q+E E+ +REK ERER+ + + E+ +E +
Sbjct: 310 ----ERERNRKRERERERERERERQRETER----DREK----ERERKRKRQTEMDRERNR 357
Query: 1063 LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQ-ERERQCREEEELQQEEE 1121
G RE RR+ E ER+ +E + Q E+ RE R RQ ERERQ ++ + Q+E E
Sbjct: 358 QTG--REGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETE 415
Query: 1122 QLLREEREKRRRQELERQYREEEEVQQ-----EEEQLLREEPEKRRRQEL 1166
+ + EREK R E R+ E E Q+ E Q R+ +R+R L
Sbjct: 416 K--QREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTL 463
Score = 189 bits (481), Expect = 2e-47
Identities = 130/460 (28%), Positives = 253/460 (55%), Gaps = 38/460 (8%)
Query: 1159 EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDED 1218
E RR+ L + +++ + +E + ++E+E+RR++R+ + + + +R++ K R+R D
Sbjct: 35 ESPRRRGLGQAHKDADGDDRERNR--QKERERRREKRQTERETDRKRERRREKDRHRKRD 92
Query: 1219 QRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERD 1278
+ + + E E+E RE ++ R+ E ++ ++R+ + + + G ++ D
Sbjct: 93 RHRERQRDREKERERQT--------DRERDRQREKERNRQKERERETEREGERGRDRQTD 144
Query: 1279 REQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKF 1338
++ER R QRD E Q +RE Q++ +R +R+ + E++ R+ER E+ R+
Sbjct: 145 GQRERER--QRDAEKERERQTDRERQRQTER-NRQKEREREKNRQERRERERQ------- 194
Query: 1339 REEEQLLQEREEQPLRRQERDRKFREEELRHQ----EQGRKFLEEEQRLRRQERERKFLK 1394
RE+E ++R + R +ER+R+ E R + E+ R+ E +R ++ ERER +
Sbjct: 195 REKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASER 254
Query: 1395 EEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQ 1454
E ++ + +ERE+ +DRDR+ +E E+Q R+ + R R+ E + +R+ + + E E+
Sbjct: 255 ETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERN 314
Query: 1455 LRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPE 1514
++ER R+ E + +E E + +ER RK E + R ++ R+ R Q R +E E
Sbjct: 315 RKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERE 374
Query: 1515 RKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR 1574
R E ++Q R++ +R+ ++ + R++ER +Q +DRD + E+Q +ERE+ + S
Sbjct: 375 R---ERDRQSAREREERE--RDRDRDRQKERERQTEKDRDGQRETEKQ--REREKDRESE 427
Query: 1575 QERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLR 1614
+ R+R E+QK R +++ER Q RQ G+Q+ R
Sbjct: 428 RGRERGREREKQKGRERDRER-------QTDRQAGRQRKR 460
Score = 186 bits (473), Expect = 1e-46
Identities = 133/488 (27%), Positives = 251/488 (51%), Gaps = 49/488 (10%)
Query: 497 REQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEK 556
+E RR + + ++ RQ+E ER +++ ++E++ R++E RRE+ R+ ++
Sbjct: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR 93
Query: 557 RLEQER-REQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEER 615
E++R RE+ +R+ + RD+ ++E R+++R +RE E E+ R+ + E+E +
Sbjct: 94 HRERQRDREKERERQTDRERDRQREKERNRQKER-ERETEREGERGRDRQTDGQRERERQ 152
Query: 616 REQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKRE 675
R+ +RE + RQ+ + Q+ER +++ R+E++ER QR K + E+R +R RE
Sbjct: 153 RDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSER-GRE 211
Query: 676 HEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQ 735
E ER + E +++ RER + R + + + K R R E + R ++
Sbjct: 212 RERERETETETERKRQTDRERDRQR----------KTEREREKQAERERASERETERDKE 261
Query: 736 EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRE 795
E+ R R+ + +++ER RQ + QRR + + ++ER R+R QRE
Sbjct: 262 RERERDRDRDRDRRQKER-ERQTDRKRQRRT-----ERDRETERKRER---------QRE 306
Query: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDG 855
R+ R ER ++ +R E E+E++R R+REKE RER ++ Q E D
Sbjct: 307 RE-RERERNRKRERERERERERERQRETERDREKE------------RERKRKRQTEMD- 352
Query: 856 LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQR 915
R R+++ R+ + + + E ER+R R A+ +E+ R + Q+E E
Sbjct: 353 ------RERNRQTGREGRRQAERERERERERDRQSARER-EERERDRDRDRQKERERQTE 405
Query: 916 EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLG 975
++R+ +R E++R+ ++ + ++ E+ E++K R ++RERQ + Q+K L
Sbjct: 406 KDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYV 465
Query: 976 EEPEKRRR 983
P + R
Sbjct: 466 NPPPRTAR 473
Score = 186 bits (471), Expect = 3e-46
Identities = 125/475 (26%), Positives = 248/475 (52%), Gaps = 43/475 (9%)
Query: 529 QQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQ 588
++R S++ RR + + ++ +R Q+ RE+R ++ Q ER KRE R +
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETD-RKRERRREKD 86
Query: 589 RLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLR 648
R ++ R QR + +E ER ER QR K ++ER ++ + E+ RQ +
Sbjct: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQ 146
Query: 649 REQQERREQRLKREEEEERLEQR-LKREHEEERREQELAEEEQEQARERIKSRIPKWQWQ 707
RE++ +R+ +RE + +R QR +R ++ER ++ +E +E+ R+R K
Sbjct: 147 RERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREK--------- 197
Query: 708 LESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDF 767
E++ + R S+ R R++E +R + + E++R+ + E Q + R++Q E +R
Sbjct: 198 -ENKTEDRHSE---RGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERAS- 252
Query: 768 TWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRER 827
+ + E ER R+R R R Q+ER+ + + ++QR E ++E R++ R+R
Sbjct: 253 --ERETERDKERERERDRDRDRDRRQKERERQTDRKRQRR-----TERDRETERKRERQR 305
Query: 828 EKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRH 887
E+E E E+ ++RER ++ + E + +E R +E+ R++K + Q E +R+R R
Sbjct: 306 ERE----RERERNRKRERERERERER---ERQRETERDREKERERKRKRQTEMDRERNRQ 358
Query: 888 TLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREE 947
T +E + E E E +RE + R+ +ER+ + Q+E E+ ++
Sbjct: 359 T-----------GREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKD 407
Query: 948 REKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQ 1002
R+ +R E++R+ KD++ ++ E+ G E EK++ +ER+++ + + + ++ ++
Sbjct: 408 RDGQRETEKQREREKDRESERGRER--GREREKQKGRERDRERQTDRQAGRQRKR 460
Score = 183 bits (465), Expect = 1e-45
Identities = 129/473 (27%), Positives = 261/473 (55%), Gaps = 39/473 (8%)
Query: 1102 RRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLL--REEPE 1159
RR+ ++ L Q + ++RE+ R++E ER+ RE+ + ++E ++ R E +
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERR-REKRQTERETDRKRERRREKD 86
Query: 1160 KRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQ 1219
+ R+++ R+ R+ + ++ E Q RE +R +ER RQ E E +R+ + R R D
Sbjct: 87 RHRKRDRHRE-RQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDG 145
Query: 1220 RSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDR 1279
+ + + Q + EKE RE + R+ + R+RQ +++ + E++ER+R
Sbjct: 146 QRERERQRDAEKE------------RERQTDRERQRQTERNRQKEREREKNRQERRERER 193
Query: 1280 EQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFR 1339
++E+ + DRH + ERE + E + +RK Q +++ R+ + E+ R ++ +R+
Sbjct: 194 QREKEN-KTEDRHSERGRERERERETETE-TERKRQTDRERDRQRKTEREREKQAERERA 251
Query: 1340 EEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL 1399
E + +++E + R ++RDR R++E Q + +R RR ER+R E ++
Sbjct: 252 SERETERDKERERERDRDRDRDRRQKERERQ-------TDRKRQRRTERDR----ETERK 300
Query: 1400 RCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQER 1459
R ++RE++ ++R+RK RE E++ +ER+R+ + E ++ R +ERERK + + ++ +ER
Sbjct: 301 RERQRERERERERNRK-RERERE---RERERERQRETERDREKERERK-RKRQTEMDRER 355
Query: 1460 HRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLE 1519
+R+ E + ERE ++ +ERDR+ E ++ R ++RDR +++ R E +R
Sbjct: 356 NRQTGREGRRQAERERER--ERERDRQSAREREE-RERDRDRDRQKERERQTEKDRDGQR 412
Query: 1520 EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQL 1572
E ++ +++ R+ E + R +ER +Q+ ++RDR+ + + Q ++R+ L
Sbjct: 413 ETEKQREREKDRE--SERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTL 463
Score = 183 bits (465), Expect = 1e-45
Identities = 135/467 (28%), Positives = 255/467 (54%), Gaps = 41/467 (8%)
Query: 1072 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131
RR+ ++ + L Q + ++ E+ R++ERER+ RE+ + ++E ++ REK
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERR-REKRQTERETDRKRERRREKD 86
Query: 1132 RRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKR 1191
R ++ +R + + ++E E+ E +++R +E RQ E E ++E E+ R+ Q
Sbjct: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERG-RDRQTDG 145
Query: 1192 RQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFR 1251
++ERERQ E+E +RQ ++R R ++ Q E E+E ++ RE E+ R
Sbjct: 146 QRERERQRDAEKERERQTDRERQRQTERNR----QKEREREKNRQER------RERERQR 195
Query: 1252 QLEDSQLRDRQSQQDLQHLLGEQQERDR--EQERRRWQQRDRHFPEEEQLEREEQKEAKR 1309
+ E+ + DR S++ G ++ER+R E E R +Q DR + + ERE +K+A+
Sbjct: 196 EKEN-KTEDRHSER------GRERERERETETETERKRQTDRERDRQRKTEREREKQAE- 247
Query: 1310 RDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRH 1369
R+R S+ E + +E E+ R ++ DR+ +E E+ + + RR ERDR+ + R
Sbjct: 248 RERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQ---RRTERDRETERKRERQ 304
Query: 1370 QEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERD 1429
+E+ R E +R R++ERER+ +E ++ R ER+++ ++R RK + E + ++
Sbjct: 305 RERER----ERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTG 360
Query: 1430 RKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLE 1489
R+ R + ++ R +ERER ++Q +ER + R+ + ++R++++ + E+DR
Sbjct: 361 REGRRQAERERERERER-----DRQSAREREERERDRD---RDRQKERERQTEKDRDGQR 412
Query: 1490 EEQQLRRQERDRKFREQELRSQEPER---KFLEEEQQLHRQQ-RQRK 1532
E ++ R +E+DR+ R +E E+ + + E+Q RQ RQRK
Sbjct: 413 ETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRK 459
Score = 183 bits (465), Expect = 1e-45
Identities = 121/439 (27%), Positives = 230/439 (52%), Gaps = 34/439 (7%)
Query: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ 645
R++ ++E+E R E+R E +R + R + R ++ + ER++ ++E+ R++
Sbjct: 54 RERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQR------DREKERER 107
Query: 646 QLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQ 705
Q RE+ +RE+ R++E ER +RE E R Q + E+E+ R+ K R
Sbjct: 108 QTDRERDRQREKERNRQKERER---ETEREGERGRDRQTDGQRERERQRDAEKER----- 159
Query: 706 WQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRR 765
E + D + + R R++E +R + QE + R R+ E + + E+R + +E E+ R
Sbjct: 160 ---ERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERER 216
Query: 766 DFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRR 825
+ + + E K + R+R R RE RE+Q E +RE E +KE+ R + R
Sbjct: 217 ET--ETETERKRQTDRERDRQRKTERE-REKQAERERASERET-----ERDKERERERDR 268
Query: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR 885
+R+++ + E E Q R+ + + ++ E + +++R R +E+ R++K + E ER+R
Sbjct: 269 DRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERE 328
Query: 886 RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLR 945
R + +E+ RK ++ + + E ++ RE RR+ E+ER+ E Q E+ R
Sbjct: 329 RQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREER 388
Query: 946 E-EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
E +R++ R++ERERQ KD+ Q+ E EK+R +E++++ E +E E+
Sbjct: 389 ERDRDRDRQKERERQTEKDRDGQR--------ETEKQREREKDRESERGRERGREREKQK 440
Query: 1005 REEREKRRRQEWERQYRKK 1023
ER++ R+ + + ++K
Sbjct: 441 GRERDRERQTDRQAGRQRK 459
Score = 183 bits (464), Expect = 2e-45
Identities = 133/453 (29%), Positives = 254/453 (56%), Gaps = 40/453 (8%)
Query: 1407 QLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREE 1466
Q +D D RE +Q R+ R K + E + R++ER R E+++ +++RHR E
Sbjct: 44 QAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRR---EKDRHRKRDRHR----E 96
Query: 1467 EQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHR 1526
Q +E+E ++ +ERDR+ E+++ R++ER+R+ + R ++ Q +
Sbjct: 97 RQRDREKERERQTDRERDRQ--REKERNRQKERERETEREGERGRD--------RQTDGQ 146
Query: 1527 QQRQRKFLQEEQQLRRQERGQQRRQDRDR-KFREEEQLRQEREEQQLSRQERDRKFRLEE 1585
++R+R+ E+++ R+ +R +QR+ +R+R K RE E+ RQER E++ R++ ++
Sbjct: 147 RERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS 206
Query: 1586 QKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKF 1645
++ R +E+ER+ E E + +RQ +++ RQ + + RE + ERE ERD+
Sbjct: 207 ERGRERERERE-TETETERKRQTDRERDRQRKTEREREKQ---AERERASERETERDK-- 260
Query: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705
ERE++ DRDR R++E+ Q ++Q RR ERDR+ + ++ R +ER
Sbjct: 261 ----------ERERERDRDRDRDRRQKERERQTDRKRQ-RRTERDRETERKRERQRERER 309
Query: 1706 ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLR 1765
ER+ ++ ++ R +E ER+ + E + +E E+E R+++R ++ E + RE ++
Sbjct: 310 ERERNRKRERERERERERERQRETERDREKERE--RKRKRQTEMDRERNRQTGREGRRQA 367
Query: 1766 RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEE 1825
+ER+R+ + Q +EREE++ R ++ DR+ E Q ++R+ Q+ +QR+ + E
Sbjct: 368 ERERERERERDRQSAREREERE-RDRDRDRQKERERQTEKDRDGQRETEKQREREKDRES 426
Query: 1826 E--QLQLEEQEQRLRQERDRQYRAEEQFATQEK 1856
E + + E+E++ +ERDR+ + + Q Q K
Sbjct: 427 ERGRERGREREKQKGRERDRERQTDRQAGRQRK 459
Score = 179 bits (454), Expect = 2e-44
Identities = 122/453 (26%), Positives = 245/453 (54%), Gaps = 29/453 (6%)
Query: 1197 RQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDS 1256
R+ +E +R+ Q ++D D D + + E+E R ++ + E
Sbjct: 29 RRPGSQESPRRRGLGQAHKDADG-DDRERNRQKERER-----------RREKRQTERETD 76
Query: 1257 QLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKR------- 1309
+ R+R+ ++D +ER R++E+ R +Q DR + + ER QKE +R
Sbjct: 77 RKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGE 136
Query: 1310 --RDRKSQEEKQLLREEREEKRRRQETDR-KFREEEQLLQEREEQPLRRQERDRKFREEE 1366
RDR++ +++ R+ EK R ++TDR + R+ E+ Q+ E+ RQER + R+ E
Sbjct: 137 RGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQRE 196
Query: 1367 LRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQ 1426
++ + R E R R +ERE + E ++ +ER++Q + +R+R+ + E ++ S +
Sbjct: 197 KENKTEDRH--SERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASER 254
Query: 1427 ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRK 1486
E +R E ++ R ++R+R+ E E+Q ++R R+ + + ++RE Q+ +ER+R
Sbjct: 255 ETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERN 314
Query: 1487 FLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQ--RKFLQEEQQLRRQE 1544
E ++ R +ER+R+ + R +E ERK + + + RQ R+ ++ ++ R +E
Sbjct: 315 RKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERE 374
Query: 1545 RGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQL 1604
R + R+ R+R+ RE ++ R +R++++ + E+DR + E +K R +E++R+ + +
Sbjct: 375 RERDRQSAREREERERDRDR-DRQKERERQTEKDRDGQRETEKQREREKDRE--SERGRE 431
Query: 1605 RRQEGQQQLRQERDRKFREDEQLLQEREEQQLH 1637
R +E ++Q +ERDR+ + D Q ++R+ L+
Sbjct: 432 RGREREKQKGRERDRERQTDRQAGRQRKRSTLY 464
Score = 174 bits (442), Expect = 6e-43
Identities = 131/469 (27%), Positives = 258/469 (55%), Gaps = 37/469 (7%)
Query: 1322 REEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQ 1381
R +E RR+ + ++ + +ER R++ER+R+ RE+ +E RK +
Sbjct: 30 RPGSQESPRRRGLGQAHKDADGDDRERN----RQKERERR-REKRQTERETDRK----RE 80
Query: 1382 RLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVR- 1440
R R ++R RK + ++ R +E+E++ + DR+R + E+++ ++ER+R+ E ++ R
Sbjct: 81 RRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRD 140
Query: 1441 RQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERD 1500
RQ ++ E ++ +ER R+ E Q ER Q+ +E++R+ E ++ R +E
Sbjct: 141 RQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK 200
Query: 1501 RKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE 1560
+ R E R +E ER E + +R+R+ +E + R+ ER ++++ +R+R E
Sbjct: 201 TEDRHSE-RGRERER----ERETETETERKRQTDRERDRQRKTEREREKQAERERASERE 255
Query: 1561 EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRK 1620
+ +ERE ++ ++RDR+ + E++ R+ Q R+ D + R++E Q++ +ER+R
Sbjct: 256 TERDKERERERDRDRDRDRRQKERERQTDRKRQ-RRTERDRETERKRERQRERERERERN 314
Query: 1621 FREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGE 1680
+ + + +ERE ++ ERDR E+E R ++R++Q DR+R Q +EG
Sbjct: 315 RKRERERERERERERQRETERDR---EKE---RERKRKRQTEMDRER----NRQTGREGR 364
Query: 1681 EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL 1740
Q R +ER+R+ R+ + R+ERER + + R++E ER+ ++ ++ETE+++
Sbjct: 365 RQAERERERERE-RDRQSAREREERER----DRDRDRQKERERQTEKDRDGQRETEKQRE 419
Query: 1741 RRQERYRKILEEEQLRPE-REEQQLRRQERDRKFREEEQLRQEREEQQL 1788
R ++R E E+ R RE ++ + +ERDR+ + + Q ++R+ L
Sbjct: 420 REKDR-----ESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTL 463
Score = 174 bits (442), Expect = 6e-43
Identities = 124/459 (27%), Positives = 247/459 (53%), Gaps = 32/459 (6%)
Query: 1474 EEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKF 1533
++++ +RQ+ + E+ Q R +R R+ R ++ R ++ +R E Q+ ++R+R+
Sbjct: 52 DDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRH--RERQRDREKERERQT 109
Query: 1534 LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593
+E + R +ER +Q+ ++R+ + RE E+ R + + Q R ER R E ++ +E+
Sbjct: 110 DRERDRQREKERNRQKERERETE-REGERGRDRQTDGQRER-ERQRDAEKERERQTDRER 167
Query: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLR 1653
+R+ + Q+ R +E +Q R+ER+R+ RE E ++R ++ +ER+R+ E E + +
Sbjct: 168 QRQTERNRQKEREREKNRQERRERERQ-REKENKTEDRHSERGRERERERE-TETETERK 225
Query: 1654 RQ---EREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFL 1710
RQ ER++Q + +R+R+ + E + E E ++ + +ER+R R+ ++ R++ERER+
Sbjct: 226 RQTDRERDRQRKTEREREKQAERERASERETERDKERERERD-RDRDRDRRQKERERQTD 284
Query: 1711 QEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERD 1770
++ Q+ ++ E + + E Q +E E+E+ R++ER R+ ERE ++ R ERD
Sbjct: 285 RKRQRRTERDRETERKRERQRERERERERNRKRERERE--------RERERERQRETERD 336
Query: 1771 RKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQL 1830
R+ E + +++ E + R++++ R+ R + + +ERE ++ R R
Sbjct: 337 REKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAR------------- 383
Query: 1831 EEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQK 1890
E +E+ ++RDRQ E Q +++ + E E +E E+ R ER R+ E +++ +
Sbjct: 384 EREERERDRDRDRQKERERQ-TEKDRDGQRETEKQREREKDRESERGRERGREREKQKGR 442
Query: 1891 EEQRHRQVGEIKSQEGKGHGRLLEPGTHQFASVPVRSSP 1929
E R RQ ++ K + P S V+S P
Sbjct: 443 ERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDP 481
Score = 174 bits (442), Expect = 6e-43
Identities = 119/450 (26%), Positives = 250/450 (55%), Gaps = 35/450 (7%)
Query: 1378 EEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQ 1437
++ +R R++ERER+ K + + R +R+++ R+++DR R+ ++ RQ RDR+ E Q
Sbjct: 52 DDRERNRQKERERRREKRQTE-RETDRKRERRREKDRH-RKRDRHRERQ-RDREKERERQ 108
Query: 1438 QVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQ 1497
R ++R+R E+E+ ++ER R+ E + + R+ Q ++ER+R+ E+++ R+
Sbjct: 109 TDRERDRQR---EKERNRQKERERETEREGE--RGRDRQTDGQRERERQRDAEKERERQT 163
Query: 1498 ERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKF 1557
+R+R+ + + R +E ER+ +E++ +QR+++ E+ R ERG++R ++R+ +
Sbjct: 164 DRERQRQTERNRQKEREREKNRQERRERERQREKENKTED---RHSERGRERERERETET 220
Query: 1558 REEEQLRQEREEQQLSRQERDRKFRLEEQKV------RRQEQERKFMEDEQQLRRQ-EGQ 1610
E + + +RE + + ER+R+ + E ++ R +E+ER+ D + RRQ E +
Sbjct: 221 ETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERE 280
Query: 1611 QQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFR 1670
+Q ++R R+ D + ++RE Q+ +ER+R E + R +ERE+Q +RDR+
Sbjct: 281 RQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKE 340
Query: 1671 EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ 1730
E + ++ E + R ++ R+ R + ++ R +ERER R+ +
Sbjct: 341 RERKRKRQTEMDRERNRQTGREGRRQAERERERERERD-----------------RQSAR 383
Query: 1731 LRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRS 1790
R+E E+++ R +++ R+ E+ +RE ++ R +E+DR+ + +ERE+Q+ R
Sbjct: 384 EREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRE 443
Query: 1791 QESDRKFREEEQLRQEREEQQLRPQQRDGK 1820
++ +R+ + +++R + P R +
Sbjct: 444 RDRERQTDRQAGRQRKRSTLYVNPPPRTAR 473
Score = 154 bits (388), Expect = 1e-36
Identities = 105/401 (26%), Positives = 222/401 (55%), Gaps = 22/401 (5%)
Query: 1529 RQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKV 1588
R+R Q + +R + R+++R+R+ RE+ Q +E + ++ R+E+DR + + +
Sbjct: 38 RRRGLGQAHKDADGDDRERNRQKERERR-REKRQTERETDRKRERRREKDRHRKRDRHRE 96
Query: 1589 RRQ--EQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFL 1646
R++ E+ER+ D ++ R++E ++ ++ER+R+ + + + R+ Q ++ER+R+
Sbjct: 97 RQRDREKERERQTDRERDRQREKERNRQKERERETEREGE--RGRDRQTDGQRERERQRD 154
Query: 1647 EEEPQLRRQEREQQLRHDRDR-KFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705
E+ + R+ +RE+Q + +R+R K RE E+ QE E++ +R++ ++ ++ R +ER
Sbjct: 155 AEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERER 214
Query: 1706 ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLR 1765
ER+ E ++ R+ + ER + + + +E + E+ R ER + +E + +R+ + R
Sbjct: 215 ERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDR 274
Query: 1766 RQ---------ERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQ 1816
RQ +R R+ + + ++RE Q+ R +E +R + E + +ERE ++ R +
Sbjct: 275 RQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETE 334
Query: 1817 RD-GKYRWEEEQLQLEEQEQRLRQ-----ERDRQYRAEEQFATQEKSRREEQELWQEEEQ 1870
RD K R + + Q E +R RQ R + E + +S RE +E ++ ++
Sbjct: 335 RDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDR 394
Query: 1871 KRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGR 1911
R++ERER+ ++ +++ E+QR R+ + +S+ G+ GR
Sbjct: 395 DRQKERERQTEKDRDGQRETEKQRERE-KDRESERGRERGR 434
Score = 150 bits (380), Expect = 9e-36
Identities = 102/384 (26%), Positives = 210/384 (54%), Gaps = 19/384 (4%)
Query: 1537 EQQLRRQERGQQRRQ-DRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQER 1595
++ RR+ GQ + D D + R ++ R+ R E++ + +E DRK +K R ++++R
Sbjct: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR 93
Query: 1596 KFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQ 1655
+ Q+ R +E ++Q +ERDR+ ++ +ERE + ER R + R +
Sbjct: 94 H--RERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRD--RQTDGQRER 149
Query: 1656 EREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQ 1715
ER++ +R+R+ E Q E Q+ R +E++R+ R E ++ R +E + + E+
Sbjct: 150 ERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERG 209
Query: 1716 LRRQELERKFREEEQLRQETEQEQ--LRRQERYRKILEEEQLRPEREEQQLRRQERDRKF 1773
R +E ER+ E + +++T++E+ R+ ER R+ E + ERE ++ + +ER+R
Sbjct: 210 -RERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERD- 267
Query: 1774 REEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQ 1833
R+ ++ R+++E ++ ++ R+ + + ++RE Q+ R ++R+ + E E+ + E+
Sbjct: 268 RDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERER 327
Query: 1834 EQRLRQERDRQYRAEEQFATQ-----EKSRREEQELWQEEEQKRRQERER-----KLREE 1883
E++ ERDR+ E + Q E++R+ +E ++ E++R +ERER + REE
Sbjct: 328 ERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREE 387
Query: 1884 HIRRQQKEEQRHRQVGEIKSQEGK 1907
R + ++ Q+ R+ K ++G+
Sbjct: 388 RERDRDRDRQKERERQTEKDRDGQ 411
Score = 50.1 bits (118), Expect = 2e-05
Identities = 30/135 (22%), Positives = 69/135 (51%), Gaps = 1/135 (0%)
Query: 1771 RKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQL 1830
R+ +E R+ Q + + D + R ++ R+ R E++ ++ D K E+ +
Sbjct: 29 RRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRH 88
Query: 1831 EEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQK 1890
++++ ++RDR+ E Q +E+ R+ E+E +++E++R ERE + + Q+
Sbjct: 89 RKRDRHRERQRDREKERERQ-TDRERDRQREKERNRQKERERETEREGERGRDRQTDGQR 147
Query: 1891 EEQRHRQVGEIKSQE 1905
E +R R + + ++
Sbjct: 148 ERERQRDAEKERERQ 162
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 218 bits (556), Expect = 3e-56
Identities = 277/1195 (23%), Positives = 538/1195 (45%), Gaps = 158/1195 (13%)
Query: 218 LRRKGREEKQQQRR-----ERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ 272
L RK ++QQQ +R + + +W + T ++ + ++EE E+
Sbjct: 794 LARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEE-----EMM 848
Query: 273 EEEEQLRKLERQELRRERQEEEQQQ-------QRLRREQQLRRKQEEERREQQEERREQQ 325
+EE+L K+ ++L E + E + ++L+ ++QL+ + E ++ R
Sbjct: 849 AKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTA 908
Query: 326 ERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR 385
+++E +E + + R E+EE R Q L+ E+++ ++ Q EQ EE E+ R++ QL +
Sbjct: 909 KKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEE--EESARQKLQLEK 966
Query: 386 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ 445
+ ++L EQ + +Q + ++ + + E +EEE+ + + + + +
Sbjct: 967 VTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHE 1026
Query: 446 RLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQ 505
+ + EER R EE +R E E+ +++L+ D + L + E + Q +
Sbjct: 1027 AMITDLEER----LRREEKQRQELEKTRRKLEGDSTD------LSDQIAELQAQIAELKM 1076
Query: 506 QLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQ 565
QL +++EE + + +EE + L+ ++L + E +E L+ E R + E++++
Sbjct: 1077 QLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQED-LESERASRNKAEKQKR 1135
Query: 566 RLKREQEERRDQL---LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKR 622
L E E + +L L +++ R KREQE + ++ EE + + + +E R K
Sbjct: 1136 DLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEA-KTHEAQIQEMRQKH 1194
Query: 623 EEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQ-RLKREHEEERR 681
+ EE +QL EQ +R + L + +Q +R + E + L Q + EH+ ++
Sbjct: 1195 SQAVEELAEQL----EQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKV 1250
Query: 682 EQELAE-----EEQEQARERIKSRIPKWQWQLE------SEADARQSKVYS-----RPRK 725
E +L E E E+ R + ++ K Q +L+ S++D++ SK+ +
Sbjct: 1251 EAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQL 1310
Query: 726 QEGQRRRQEQEEKRRRRESEL-QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRL 784
Q+ Q QE+ ++ ++L Q ++E+ + R+Q EEE+ +A+ E+ L
Sbjct: 1311 QDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEE--------EAKHNLEKQIATL 1362
Query: 785 SAR-PPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRR 843
A+ ++++ E + E + +R L +K+ +R EK + + E+ R
Sbjct: 1363 HAQVADMKKKMEDSVGCLETAEEVKRKL----QKDLEGLSQRHEEKVAAYDKLEKTKTR- 1417
Query: 844 ERAQQLQEEEDGLQEDQERRRSQE---QRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR 900
LQ+E D L D + +R +++ +K+ L EE+ T+ AK A +E+ R
Sbjct: 1418 -----LQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEK-----TISAKYA-EERDR 1466
Query: 901 KEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQY 960
E + ++E + L + +++ R +Q + E E L+ + +
Sbjct: 1467 AEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDD----------V 1516
Query: 961 RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR-EEREKRRRQEWERQ 1019
K +K ++ L ++ E+ + Q E E+ELQ E+ LR E + + ++ER
Sbjct: 1517 GKSVHELEKSKRALEQQVEEMKTQLEEL----EDELQATEDAKLRLEVNLQAMKAQFERD 1572
Query: 1020 YRKKDELQQE-EEQLLREEREKRRLQERERQYRE-----EEELQQEEEQLLGE-ERETRR 1072
+ +DE +E ++QL+R+ RE E ER+ R ++L+ + + L + +
Sbjct: 1573 LQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKN 1632
Query: 1073 RQELERQYRKEEELQQEEEQLLREEPEKR-RRQERERQCREEE--------ELQQEEEQL 1123
R E +Q RK LQ + + +RE + R R+E Q +E E E+ Q +E+L
Sbjct: 1633 RDEAIKQLRK---LQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEEL 1689
Query: 1124 LREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQL 1183
ER KR+ Q+ ER +E + L E EKRR + Q EE E +Q +L
Sbjct: 1690 AAAERAKRQAQQ-ERDELADEIANSSGKGALALE-EKRRLEARIAQLEEELEEEQGNTEL 1747
Query: 1184 LREEQEK--------------RRQERERQYREEEELQRQKRKQRYRDEDQRSDLK----- 1224
+ + +K R ++ ++L+RQ ++ + + ++ +K
Sbjct: 1748 INDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKA 1807
Query: 1225 ---------WQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQ 1275
Q E + +N ++ + CK Q R+ E +L+D Q D + EQ
Sbjct: 1808 SITALEAKIAQLEEQLDNETKERQAACK-----QVRRTE-KKLKDVLLQVDDERRNAEQY 1861
Query: 1276 ERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRR 1330
+ ++ R +Q R E E EE + A RK Q E + E + R
Sbjct: 1862 KDQADKASTRLKQLKRQLEEAE----EEAQRANASRRKLQRELEDATETADAMNR 1912
Score = 212 bits (540), Expect = 3e-54
Identities = 262/1115 (23%), Positives = 524/1115 (46%), Gaps = 141/1115 (12%)
Query: 162 EQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRR---ELLEL 218
++ + ++EEL + R++ E R E E LQS E + ++ Q E EL
Sbjct: 843 QEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEEL 902
Query: 219 RRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
R + +KQ+ D + EEE+E R L+ E++K+Q+ + + +L+EEE
Sbjct: 903 RARLTAKKQELEEICHDLEARVEEEEE---RCQHLQAEKKKMQQNIQELEEQLEEEESAR 959
Query: 279 RKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQ 338
+KL+ +++ E + ++ +++++ E Q + +E++ E+R + +EE + +
Sbjct: 960 QKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKL--LEDRIAEFTTNLTEEEEKSKS 1017
Query: 339 LRREQEERR------EQQLRREQEEERRE--QQLRREQEEERRE-----QQLRREQQLRR 385
L + + + E++LRRE E++R+ ++ RR+ E + + +L+ + +
Sbjct: 1018 LAKLKNKHEAMITDLEERLRRE--EKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELK 1075
Query: 386 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE-QQLRREQEEER-HEQKHEQERR 443
Q ++E++L+ E+ ++ L++ ++L + +L+ + E ER K E+++R
Sbjct: 1076 MQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKR 1135
Query: 444 E-----QRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERRE 498
+ + LK E E+ D ++E R ++E+ LK+ EEE + +++E ++
Sbjct: 1136 DLGEELEALKTELEDTLDSTAAQQEL-RSKREQEVNILKKTLEEEAKTHEAQIQEMRQKH 1194
Query: 499 QQERREQQLRREQEERREQRLKRQE---EEER----------LQQRLRSEQQLRREQEER 545
Q E + EQ +R + L++ + E ER LQ + SE + ++ + +
Sbjct: 1195 SQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQL 1254
Query: 546 REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKRE 605
+E +K E +R+ E ++ K + E L + + + +L ++ LE +L +
Sbjct: 1255 QELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKD-FSALESQL--Q 1311
Query: 606 EVERLEQEERREQ-----RLKREEPEEER-RQQLLKSEEQEERRQQQLRREQQERREQRL 659
+ + L QEE R++ +LK+ E E+ R+QL + EE + ++Q+ + + +
Sbjct: 1312 DTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKK 1371
Query: 660 KRE------EEEERLEQRLKREHE--EERREQELAEEEQEQARERIKSRIPKWQWQLESE 711
K E E E ++++L+++ E +R E+++A ++ E+ K+R+ + L +
Sbjct: 1372 KMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDK---LEKTKTRLQQELDDLLVD 1428
Query: 712 ADARQSKVYSRPRKQ--------EGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQ 763
D ++ + +KQ E + + E+R R E+E + +E + + EE
Sbjct: 1429 LDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEA 1488
Query: 764 RRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQ 823
Q E +Q + L ++ ++ ++ +R L E++ E+ + Q
Sbjct: 1489 ME------QKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRAL--EQQVEEMKTQ 1540
Query: 824 RREREKELQFLEEEE-QLQRRERAQQLQEEED--GLQEDQERRRSQEQRRDQKWRWQLEE 880
E E ELQ E+ + +L+ +A + Q E D G E E ++ Q R+ ++ +LE+
Sbjct: 1541 LEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELED 1600
Query: 881 ERKRRRHTLYAKPALQ---------------------EQLRKEQQLLQEEEEEL-----Q 914
ERK+R + A+ L+ +QLRK Q +++ EL
Sbjct: 1601 ERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRAS 1660
Query: 915 REEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLL 974
REE + ++ +++ E ++ Q +E+L ER KR+ Q+ ER D+ + L
Sbjct: 1661 REEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQ-ERDELADEIANSSGKGAL 1719
Query: 975 GEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ--------EWERQYRKKDEL 1026
E EKRR + R + EE E +Q +L+ + +K Q ER + +K+E
Sbjct: 1720 ALE-EKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNE- 1777
Query: 1027 QQEEEQLLREERE-KRRLQERERQYRE---------EEELQQEEEQLLGEERETRRRQEL 1076
+QL R+ +E K +LQE E + E ++ Q EEQL + ET+ RQ
Sbjct: 1778 -NARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQL---DNETKERQAA 1833
Query: 1077 ERQYRKEEELQQEEEQLLREEPEKRRRQERERQC-REEEELQQEEEQLLREEREKRR--- 1132
+Q R+ E ++ ++ LL+ + E+R ++ + Q + L+Q + QL E E +R
Sbjct: 1834 CKQVRRTE--KKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANA 1891
Query: 1133 -RQELERQYREEEEVQQEEEQLLREEPEKRRRQEL 1166
R++L+R+ + E + + K RR +L
Sbjct: 1892 SRRKLQRELEDATETADAMNREVSSLKNKLRRGDL 1926
Score = 207 bits (527), Expect = 8e-53
Identities = 255/1118 (22%), Positives = 515/1118 (46%), Gaps = 129/1118 (11%)
Query: 338 QLRREQEERREQQLRREQEEERREQQLRREQEE--ERREQQLRREQQLRREQQLRREQQL 395
+LR Q R +++ + R+E+++ ++EE + RE+QL E +L + L + QL
Sbjct: 821 KLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETL--QSQL 878
Query: 396 RREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERR 455
E+ L+ ++QL+ E +L E + R + ++QE E E H+ E R + E+EER
Sbjct: 879 MAEK-LQLQEQLQAETELCAEAEELRARLTAKKQELE--EICHDLEARVE----EEEERC 931
Query: 456 DWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERR 515
L+ E++ + + ++QL +EEE + L+LE + E + ++L EQ
Sbjct: 932 QHLQAEKKKMQQNIQELEEQL---EEEESARQKLQLE----KVTTEAKLKKLEEEQIILE 984
Query: 516 EQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERR 575
+Q K +E++ L+ R+ E+EE+ + L K + + E+RL+RE+++R+
Sbjct: 985 DQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ 1044
Query: 576 D-------------------------------QLLKREEERRQQRLKREQEERLEQRLKR 604
+ QL K+EEE Q L R +EE ++ +
Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEE-LQAALARVEEEAAQKNMAL 1103
Query: 605 EEVERLE------QEERREQRLKREEPEEERRQ-----QLLKSEEQEERRQQQLRREQQE 653
+++ LE QE+ +R R + E+++R + LK+E ++ ++E +
Sbjct: 1104 KKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRS 1163
Query: 654 RREQR---LKREEEEERLEQRLKREHEEERREQELAE-EEQEQARERIKSRIPKWQWQLE 709
+REQ LK+ EEE + + ++ Q + E EQ + +R+K+ + K + LE
Sbjct: 1164 KREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLE 1223
Query: 710 SEAD--ARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDF 767
+E A + KV + + G + ++ + + +E ++++ E ER + ++ +
Sbjct: 1224 NERGELANEVKVLLQGK---GDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQV 1280
Query: 768 TWQ------WQAEEKSERGRQRLSARPPLREQRERQLRAEERQQ--REQRFLPEEEEKEQ 819
Q++ KS + + SA + + L+ E RQ+ + E+EK
Sbjct: 1281 ELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNS 1340
Query: 820 RRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLE 879
R Q E E+ LE++ + A ++ ED + E + K + Q +
Sbjct: 1341 FREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSV-------GCLETAEEVKRKLQKD 1393
Query: 880 EERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQRE-EREKRRRQEQERQYREEEQLQQ 938
E +RH K A ++L K + LQ+E ++L + + +++ E++ ++ +QL
Sbjct: 1394 LEGLSQRHE--EKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLA 1451
Query: 939 EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQER-EKKYREE-EEL 996
EE+ + + E+R R E E + ++ K L + L E E++ ER K++R E E+L
Sbjct: 1452 EEKTISAKYAEERDRAEAEAREKETKALSL--ARALEEAMEQKAELERLNKQFRTEMEDL 1509
Query: 997 QQEEEQLLR--EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ---------- 1044
++ + + E EK +R ++ K +L++ E++L E K RL+
Sbjct: 1510 MSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQF 1569
Query: 1045 ERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKR--- 1101
ER+ Q R+E+ +++++QL+ + RE E ER+ R +++ ++ ++ E
Sbjct: 1570 ERDLQGRDEQS-EEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDS 1628
Query: 1102 RRQERERQCREEEELQQEEEQLLREEREKR-RRQELERQYREEE--------EVQQEEEQ 1152
+ R+ ++ +LQ + + +RE + R R+E+ Q +E E E+ Q +E+
Sbjct: 1629 ANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEE 1688
Query: 1153 LLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQ 1212
L E KR+ Q+ ER +E + L E+++R + R Q EE E + Q +
Sbjct: 1689 LAAAERAKRQAQQ-ERDELADEIANSSGKGALALEEKRRLEARIAQLEEELE-EEQGNTE 1746
Query: 1213 RYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRD-RQSQQDLQHLL 1271
D ++++L+ N R + ++NE RQ + Q ++ + Q+++ +
Sbjct: 1747 LINDRLKKANLQIDQINTDLNLERSH-----AQKNENARQQLERQNKELKVKLQEMEGTV 1801
Query: 1272 GEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREER----EE 1327
+ + + Q + E + + K+ +R ++K ++ + +ER +
Sbjct: 1802 KSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQY 1861
Query: 1328 KRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365
K + + + ++ ++ L+E EE+ R RK + E
Sbjct: 1862 KDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRE 1899
Score = 200 bits (508), Expect = 1e-50
Identities = 273/1159 (23%), Positives = 531/1159 (45%), Gaps = 162/1159 (13%)
Query: 839 QLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQ 898
Q+ R+E +EEE L + +E++ + E R L E + + K LQEQ
Sbjct: 839 QVSRQEEEMMAKEEE--LVKVREKQLAAENR--------LTEMETLQSQLMAEKLQLQEQ 888
Query: 899 LRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERER 958
L+ E +L E EE R ++++ +E + E ++++EEE+ + EK++ Q+
Sbjct: 889 LQAETELCAEAEE--LRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQN-- 944
Query: 959 QYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQ-EEEQLLREEREKRRRQEWE 1017
+Q+ EEQL EE E R++ + +K E +L++ EEEQ++ E++ + +E
Sbjct: 945 -------IQELEEQL--EEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKE-- 993
Query: 1018 RQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELE 1077
+ +D + + L EE + + L + + ++ E + EE+L RE ++RQELE
Sbjct: 994 -KKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKH--EAMITDLEERL---RREEKQRQELE 1047
Query: 1078 RQYRK-EEELQQEEEQLLREEPEKRRRQERERQCREEEELQ----QEEEQLLREEREKRR 1132
+ RK E + +Q+ E + + + + + ++EEELQ + EE+ ++ ++
Sbjct: 1048 KTRRKLEGDSTDLSDQIA--ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKK 1105
Query: 1133 RQELERQYREEEEVQQEEEQLLREEPEKRRR---QELERQYRE----------EEELQQE 1179
+ELE Q E +E E E+ R + EK++R +ELE E ++EL+ +
Sbjct: 1106 IRELESQISELQE-DLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSK 1164
Query: 1180 EEQ---LLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVR 1236
EQ +L++ E+ + E Q +E + Q ++ +Q +K E K+
Sbjct: 1165 REQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLEN 1224
Query: 1237 DNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEE 1296
+ +G + + L + ++ ++ L E Q + E ER R + D+ +
Sbjct: 1225 E-----RGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQ 1279
Query: 1297 EQLE-------REEQKEAKRR------DRKSQEEKQLLREEREEK-----RRRQETDRKF 1338
+L+ + + K +K + + Q+ ++LL+EE +K + +Q D K
Sbjct: 1280 VELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKN 1339
Query: 1339 REEEQLLQEREEQ--------PLRRQERDRKFREEE----LRHQEQGRKFLEEEQRLRRQ 1386
EQL +E E + L Q D K + E+ L E+ ++ L+++ Q
Sbjct: 1340 SFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQ 1399
Query: 1387 ERERKFLK----EEQQLRCQEREQQLRQDRDR---------KFREEEQQLSRQER--DRK 1431
E K E+ + R Q+ L D D K +++ QL +E+ K
Sbjct: 1400 RHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAK 1459
Query: 1432 FREEEQQVRRQERER--------KFLEE--EQQLRQER-HRKFREE-EQLLQEREE--QQ 1477
+ EE + + RE+ + LEE EQ+ ER +++FR E E L+ +++ +
Sbjct: 1460 YAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKS 1519
Query: 1478 LHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEE 1537
+H E+ ++ LE QQ+ + + E EL++ E + LE Q + Q +R
Sbjct: 1520 VHELEKSKRALE--QQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQG-- 1575
Query: 1538 QQLRRQERGQQRRQDRDRKFRE-EEQLRQEREEQQLSRQERDR-KFRLEEQKVRRQEQER 1595
R E+ +++++ R+ RE E +L ER+++ ++ R + + L++ + +
Sbjct: 1576 ----RDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANK 1631
Query: 1596 KFMEDEQQLRRQEGQQQ--LRQERDRKFREDEQLLQERE-EQQLHRQERDRKFLEEEPQL 1652
E +QLR+ + Q + +R+ D + +E L Q +E E++L E + L+EE L
Sbjct: 1632 NRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEE--L 1689
Query: 1653 RRQER-EQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ 1711
ER ++Q + +RD +++ + L +E+ R E ++ + E E + Q
Sbjct: 1690 AAAERAKRQAQQERDEL---ADEIANSSGKGALALEEK----RRLEARIAQLEEELEEEQ 1742
Query: 1712 EEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDR 1771
+L L++ + +Q+ + E+ Q+ E QQL RQ ++
Sbjct: 1743 GNTELINDRLKKANLQIDQINTDLNLERSHAQKN------------ENARQQLERQNKEL 1790
Query: 1772 KFREEEQLRQEREEQQLRSQESDRKFRE-EEQLRQEREEQQLRPQQ-RDGKYRWEEEQLQ 1829
K + +E + + + + K + EEQL E +E+Q +Q R + + ++ LQ
Sbjct: 1791 KVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQ 1850
Query: 1830 LEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQ 1889
++++ + Q +D+ +A + Q K + EE E EE +R RKL+ E +
Sbjct: 1851 VDDERRNAEQYKDQADKASTRLK-QLKRQLEEAE----EEAQRANASRRKLQRELEDATE 1905
Query: 1890 KEEQRHRQVGEIKSQEGKG 1908
+ +R+V +K++ +G
Sbjct: 1906 TADAMNREVSSLKNKLRRG 1924
Score = 193 bits (490), Expect = 2e-48
Identities = 269/1141 (23%), Positives = 516/1141 (45%), Gaps = 145/1141 (12%)
Query: 804 QQREQRFLPEEEEKEQRRRQ--RREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQE 861
+Q E+ EEE + R +Q R E++ L+ + ++ + +QLQ E + E +E
Sbjct: 842 RQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEE 901
Query: 862 RRRSQEQRRDQ------KWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQR 915
R ++ + ++EEE +R +H LQ + +K QQ +QE EE+L+
Sbjct: 902 LRARLTAKKQELEEICHDLEARVEEEEERCQH-------LQAEKKKMQQNIQELEEQLEE 954
Query: 916 EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQL-- 973
EE R++ + E+ E + + EEEQ++ E++ + +E+ K L+ + +
Sbjct: 955 EE-SARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEK-------KLLEDRIAEFTT 1006
Query: 974 -LGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQ 1032
L EE EK + + K + E + EE+L REE++ RQE E+ RK L+ +
Sbjct: 1007 NLTEEEEKSKSLAKLKN-KHEAMITDLEERLRREEKQ---RQELEKTRRK---LEGDSTD 1059
Query: 1033 LLREERE-KRRLQERERQY-REEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEE 1090
L + E + ++ E + Q ++EEELQ ++ EE ++ L++ E ++ + +
Sbjct: 1060 LSDQIAELQAQIAELKMQLAKKEEELQAALARV--EEEAAQKNMALKKIRELESQISELQ 1117
Query: 1091 EQLLREEPEKRRRQERERQCREE-EELQQEEEQLL-----REEREKRRRQE---LERQYR 1141
E L E + + ++++R EE E L+ E E L ++E +R QE L++
Sbjct: 1118 EDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLE 1177
Query: 1142 EE--------EEVQQEEEQLLRE-----EPEKRRRQELERQYR----EEEELQQEEEQLL 1184
EE +E++Q+ Q + E E KR + LE+ + E EL E + LL
Sbjct: 1178 EEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLL 1237
Query: 1185 REEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKG 1244
+ + + + ++ + + +E + +R R E K Q E + +
Sbjct: 1238 QGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSS 1297
Query: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304
+ + F LE SQL QD Q LL E+ + + Q D EQLE EE+
Sbjct: 1298 KLTKDFSALE-SQL------QDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEE 1350
Query: 1305 KEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQL-LQEREEQPLRRQERDRKFR 1363
K EKQ+ Q D K + E+ + E E+ R+ ++D +
Sbjct: 1351 A-------KHNLEKQIAT------LHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGL 1397
Query: 1364 EEELRHQEQGRKFLEEEQRLRRQERERKFL----KEEQQLRCQEREQQLRQDRDRKFREE 1419
+ RH+E+ + + E+ R ++E L ++Q C ++Q + D+ E
Sbjct: 1398 SQ--RHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQ---LLAE 1452
Query: 1420 EQQLSR---QERDRKFREEEQQVRRQERERKFLEE--EQQLRQER-HRKFREE-EQLLQE 1472
E+ +S +ERDR E ++ + + LEE EQ+ ER +++FR E E L+
Sbjct: 1453 EKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSS 1512
Query: 1473 REE--QQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQ 1530
+++ + +H E+ ++ LE QQ+ + + E EL++ E + LE Q + Q +
Sbjct: 1513 KDDVGKSVHELEKSKRALE--QQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFE 1570
Query: 1531 RKFLQEEQQLRRQERGQQRRQDRDRKFRE-EEQLRQEREEQQLSRQERDR-KFRLEEQKV 1588
R R E+ +++++ R+ RE E +L ER+++ ++ R + + L++ +
Sbjct: 1571 RDLQG------RDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEA 1624
Query: 1589 RRQEQERKFMEDEQQLRRQEGQQQ--LRQERDRKFREDEQLLQERE-EQQLHRQERDRKF 1645
+ E +QLR+ + Q + +R+ D + +E L Q +E E++L E +
Sbjct: 1625 HIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQ 1684
Query: 1646 LEEEPQLRRQER-EQQLRHDRDRKFREEEQ-------LLQEGEEQQLRRQERDRKFREEE 1697
L+EE L ER ++Q + +RD E L+E + R + + + EE+
Sbjct: 1685 LQEE--LAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQ 1742
Query: 1698 -------QQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQE------ 1744
+L++ + + + L R ++ +QL ++ ++ +++ QE
Sbjct: 1743 GNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVK 1802
Query: 1745 -RYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQL 1803
+Y+ + + + + E+QL + ++R+ ++ R E++ + + Q D + R EQ
Sbjct: 1803 SKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDER-RNAEQY 1861
Query: 1804 RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE 1863
+ + ++ R +Q K + EE + EE ++ R Q E+ T + RE
Sbjct: 1862 KDQADKASTRLKQL--KRQLEEAE---EEAQRANASRRKLQRELEDATETADAMNREVSS 1916
Query: 1864 L 1864
L
Sbjct: 1917 L 1917
Score = 189 bits (480), Expect = 2e-47
Identities = 249/1084 (22%), Positives = 474/1084 (43%), Gaps = 120/1084 (11%)
Query: 116 EEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWR 175
EE + R + ++LEE + +E+ER E+ + Q+ +++ + Q +EE R
Sbjct: 900 EELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESAR 959
Query: 176 QRQEWQ----EREERRAEEEQL----QSCKGHETEEFPDEEQLRRRELLELRRKGREEKQ 227
Q+ + + E + ++ EEEQ+ Q+CK E++L + E EE++
Sbjct: 960 QKLQLEKVTTEAKLKKLEEEQIILEDQNCK------LAKEKKLLEDRIAEFTTNLTEEEE 1013
Query: 228 QQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELR 287
+ + K K E ++ EE+L+ EE QR QE E+ RKLE
Sbjct: 1014 KSK----------SLAKLKNKHEAMITDLEERLRREEKQR----QELEKTRRKLEGDSTD 1059
Query: 288 RERQEEEQQQQRLRREQQLRRKQEEERR--EQQEERREQQERREQQEERREQQLRREQEE 345
Q E Q Q + QL +K+EE + + EE Q+ ++ E Q+ QE+
Sbjct: 1060 LSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQED 1119
Query: 346 RREQQLRREQEEERRE------QQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQ 399
++ R + E+++ + L+ E E+ ++E + +REQ++ ++ E+
Sbjct: 1120 LESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEE 1179
Query: 400 QLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWL- 458
E Q+ Q++R++ E+ EQ E+ K E+ +Q L+ E+ E + +
Sbjct: 1180 AKTHEAQI---QEMRQKHSQAVEE--LAEQLEQTKRVKANLEKAKQTLENERGELANEVK 1234
Query: 459 -----KREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEE 513
K + E +R + E + Q+L+ E R R +L ++ + Q E Q +
Sbjct: 1235 VLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVR-TELADKVTKLQVELDNVTGLLSQSD 1293
Query: 514 RREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEE 573
+ +L + + L+ +L+ Q+L QEE R++L + K++E E+ R + E+EE
Sbjct: 1294 SKSSKLTK--DFSALESQLQDTQELL--QEENRQKLSLSTKLKQVEDEKNSFREQLEEEE 1349
Query: 574 RRDQLLKREEERRQQR---LKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERR 630
L+++ + +K++ E+ + EEV+R Q++ E +R E +
Sbjct: 1350 EAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKD-LEGLSQRHEEKVAAY 1408
Query: 631 QQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQ 690
+L K++ + ++ L + +R+ E+++++ +Q L E + E + +
Sbjct: 1409 DKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAE 1468
Query: 691 EQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQE 750
+ARE+ +++ LE + Q R KQ K +S + ++
Sbjct: 1469 AEAREK-ETKALSLARALEEAME--QKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEK 1525
Query: 751 EERAHRQQQEE--EQRRDFTWQWQAEEKSE-RGRQRLSARPPLREQRERQLRAEERQQRE 807
+RA QQ EE Q + + QA E ++ R L A ++ Q ER L+ + Q
Sbjct: 1526 SKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQA---MKAQFERDLQGRDEQ--- 1579
Query: 808 QRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQE 867
EE+K+Q RQ RE E EL E+E+ QR ++ E L++ + S
Sbjct: 1580 -----SEEKKKQLVRQVREMEAEL----EDERKQRSMAVAARKKLEMDLKDLEAHIDSAN 1630
Query: 868 QRRDQKWRW-------------QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQ 914
+ RD+ + +L++ R R L +++L+ + + + +EEL
Sbjct: 1631 KNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELA 1690
Query: 915 REEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLL 974
ER KR+ Q++ + +E + L E EKRR + R Q ++ + +Q +L+
Sbjct: 1691 AAERAKRQAQQERDELADEIANSSGKGALALE--EKRRLEARIAQLEEELEEEQGNTELI 1748
Query: 975 GEEPEKRRRQ----------EREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKK- 1023
+ +K Q ER + E QQ E Q + K + QE E + K
Sbjct: 1749 NDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQ---NKELKVKLQEMEGTVKSKY 1805
Query: 1024 --------DELQQEEEQLLREEREKRRLQERERQYREEEE---LQQEEEQLLGEERETRR 1072
++ Q EEQL E +E++ ++ R+ ++ + LQ ++E+ E+ + +
Sbjct: 1806 KASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQA 1865
Query: 1073 RQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRR 1132
+ R + + +L++ EE+ R +R+ Q E + E L + K R
Sbjct: 1866 DKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSL---KNKLR 1922
Query: 1133 RQEL 1136
R +L
Sbjct: 1923 RGDL 1926
Score = 171 bits (433), Expect = 6e-42
Identities = 210/936 (22%), Positives = 427/936 (45%), Gaps = 93/936 (9%)
Query: 110 LQDR-RQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQR 168
L++R R+EE QR+ + R+ E + E + ++AE + Q K+E Q R
Sbjct: 1032 LEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALAR 1091
Query: 169 RDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQ 228
+EE ++ ++ E ++ +LQ E LE R R + ++
Sbjct: 1092 VEEEAAQKNMALKKIRELESQISELQ-------------------EDLESERASRNKAEK 1132
Query: 229 QRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRR 288
Q+R+ + + + E E T ++E +E+E ++ EEE + + + QE+R+
Sbjct: 1133 QKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQ 1192
Query: 289 ER-QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER----------REQQEERREQ 337
+ Q E+ ++L + ++++ E+ ++ + ER E E + ++ E
Sbjct: 1193 KHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEA 1252
Query: 338 QLRREQEERRE-QQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLR 396
QL+ Q + E +++R E ++ + Q+ + Q + +L ++ E QL+
Sbjct: 1253 QLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFS-ALESQLQ 1311
Query: 397 REQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL-------KR 449
Q+L +E+ ++ + +Q+ E+ REQ EE E KH E++ L K+
Sbjct: 1312 DTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKK 1371
Query: 450 EQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR 509
+ E+ L+ EE +R Q+ + +R EE+ + KLE+ + R QQE L
Sbjct: 1372 KMEDSVGCLETAEEVKRKLQKDLEGLSQR--HEEKVAAYDKLEKTKTRLQQEL--DDLLV 1427
Query: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
+ + +R+ ++++++ Q L E+ + + E R+ R E + E+E + L R
Sbjct: 1428 DLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERD----RAEAEAREKETKALSLAR 1483
Query: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQR-------LKREEVERLEQEERREQRLKR 622
EE +Q K E ER ++ + E E+ + + + E+ +R +++ E + +
Sbjct: 1484 ALEEAMEQ--KAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQL 1541
Query: 623 EEPEEE---RRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEE 679
EE E+E L+ E + + Q R+ Q R EQ +++++ R + ++ E E+E
Sbjct: 1542 EELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDE 1601
Query: 680 RREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRR--RQEQEE 737
R+++ +A AR++++ + + ++S A+ + + + RK + Q + +E ++
Sbjct: 1602 RKQRSMA----VAARKKLEMDLKDLEAHIDS-ANKNRDEAIKQLRKLQAQMKDCMRELDD 1656
Query: 738 KRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQ 797
R RE E+ Q +E + + E + + A E+++R + Q+ER
Sbjct: 1657 TRASRE-EILAQAKENEKKLKSMEAEMIQLQEELAAAERAKR-----------QAQQERD 1704
Query: 798 LRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQ 857
A+E + EEK + + + E+EL+ + +L +R ++ + D +
Sbjct: 1705 ELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTEL-INDRLKKANLQIDQIN 1763
Query: 858 EDQERRRSQEQRRDQKWRWQLEEERKRRRHTLY-----AKPALQEQLRKEQQLLQEEEEE 912
D RS Q+ + R QLE + K + L K + + + + + EE+
Sbjct: 1764 TDLNLERSHAQKNENA-RQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQ 1822
Query: 913 LQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRK-DKKLQQKEE 971
L E +E++ +Q R R E++L ++ LL+ + E+R ++ + Q K +L+Q +
Sbjct: 1823 LDNETKERQAACKQVR--RTEKKL---KDVLLQVDDERRNAEQYKDQADKASTRLKQLKR 1877
Query: 972 QL-LGEEPEKRRRQEREKKYREEEELQQEEEQLLRE 1006
QL EE +R R K RE E+ + + + RE
Sbjct: 1878 QLEEAEEEAQRANASRRKLQRELEDATETADAMNRE 1913
Score = 112 bits (280), Expect = 4e-24
Identities = 125/573 (21%), Positives = 264/573 (46%), Gaps = 78/573 (13%)
Query: 1382 RLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRR 1441
+LR + R F K + L+ +E+++ + + E+QL+ + R + + Q+
Sbjct: 821 KLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMA 880
Query: 1442 QERERKFLEEEQQLRQERHRKFREEE---QLLQEREEQQLHRQERDRKFLEEEQQLRRQE 1498
++ L+ ++QL+ E EE +L +++E + + + + EEE++ + +
Sbjct: 881 EK-----LQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQ 935
Query: 1499 RDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFR 1558
++K +Q ++ E + LEEE+ RQ+ Q + + E +L++ E Q +D++ K
Sbjct: 936 AEKKKMQQNIQELEEQ---LEEEESA-RQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLA 991
Query: 1559 EEEQLRQER---------EEQQLSRQERDRKFRLE------EQKVRRQEQERKFMEDEQQ 1603
+E++L ++R EE++ S+ K + E E+++RR+E++R+ E E+
Sbjct: 992 KEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ--ELEKT 1049
Query: 1604 LRRQEGQQ---------------QLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEE 1648
R+ EG +L+ + +K E + L EE+ + +K E
Sbjct: 1050 RRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIREL 1109
Query: 1649 EPQLRRQEREQQLRHDRDRKFREEEQLLQEGEE-QQLRRQERDRKFREEEQQLRRQERE- 1706
E Q+ E ++ L +R + + E+Q GEE + L+ + D QQ R +RE
Sbjct: 1110 ESQI--SELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQ 1167
Query: 1707 -----RKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREE 1761
+K L+EE + +++ + R++ E EQL + +R + LE+ + E E
Sbjct: 1168 EVNILKKTLEEEAKTHEAQIQ-EMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENER 1226
Query: 1762 QQLRRQERD-RKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGK 1820
+L + + + + + + ++++ E QL QE KF E E++R E ++ +
Sbjct: 1227 GELANEVKVLLQGKGDSEHKRKKVEAQL--QELQVKFNEGERVRTELADKVTK------- 1277
Query: 1821 YRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQ---------K 1871
Q++L+ L Q + + + F+ E ++ QEL QEE + K
Sbjct: 1278 -----LQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLK 1332
Query: 1872 RRQERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904
+ ++ + RE+ ++ + +Q+ + +Q
Sbjct: 1333 QVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQ 1365
Score = 109 bits (273), Expect = 2e-23
Identities = 128/609 (21%), Positives = 275/609 (45%), Gaps = 59/609 (9%)
Query: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154
L+EE+ A+ + ++ + Q D ++ + D E + ++K Q+ L++ E+
Sbjct: 1345 LEEEEEAKHNLEKQIATLHAQVADMKK-KMEDSVGCLETAEEVKRKLQKDLEGLSQRHEE 1403
Query: 155 S----EKQERLEQRDRQRRDE---ELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDE 207
+K E+ + R +Q D+ +L QRQ E+++ + +QL + + + ++ +E
Sbjct: 1404 KVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEE 1463
Query: 208 EQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR 267
E E K + + + E K++R L ++ + + +
Sbjct: 1464 RDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHEL 1523
Query: 268 QRELQEEEEQLRKLERQ--ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325
++ + E+Q+ +++ Q EL E Q E + RL Q + Q E R+ Q
Sbjct: 1524 EKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFE---------RDLQ 1574
Query: 326 ERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR 385
R EQ EE+++Q +R+ +E + E E+ER+++ + + +
Sbjct: 1575 GRDEQSEEKKKQLVRQVRE-------------------MEAELEDERKQRSMAVAARKKL 1615
Query: 386 EQQLRREQQLRREQQLRREQQLRREQQLRRE-QQLRREQQLRREQEEERHEQKHEQERRE 444
E L+ + R++ +++ ++L+ + + RE R EE Q E E++
Sbjct: 1616 EMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKL 1675
Query: 445 QRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQ-ERR 503
+ ++ E + ++ L E +R Q+ R +L + + L LEE+ R E + +
Sbjct: 1676 KSMEAEMIQLQEELAAAERAKRQAQQER-DELADEIANSSGKGALALEEKRRLEARIAQL 1734
Query: 504 EQQLRREQ--EERREQRLKRQE-EEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQ 560
E++L EQ E RLK+ + +++ L E+ ++ E R+QL ++ +E +++
Sbjct: 1735 EEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKL 1794
Query: 561 ERREQRLKREQE----------ERRDQLLKREEERRQQRLK--REQEERLEQRLKREEVE 608
+ E +K + + + ++ L E + RQ K R E++L+ L + + E
Sbjct: 1795 QEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDE 1854
Query: 609 RLEQEERREQRLKREEPEEERRQQLLKSEEQEER---RQQQLRREQQERREQRLKREEEE 665
R E+ ++Q K ++ ++QL ++EE+ +R +++L+RE ++ E E
Sbjct: 1855 RRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREV 1914
Query: 666 ERLEQRLKR 674
L+ +L+R
Sbjct: 1915 SSLKNKLRR 1923
Score = 74.3 bits (181), Expect = 1e-12
Identities = 95/415 (22%), Positives = 186/415 (44%), Gaps = 59/415 (14%)
Query: 1497 QERDRKFREQELRSQEPERKFLEEEQQLHRQQR--QRKFLQEEQQLRRQERGQQRRQDRD 1554
+ERD K + + Q R +L + RQQ+ K LQ + R Q
Sbjct: 773 EERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWW---- 828
Query: 1555 RKFREEEQLRQ--EREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ 1612
R F + + L Q +EE+ ++++E K R ++ + E + ++ + + + Q+Q
Sbjct: 829 RLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQ 888
Query: 1613 LRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREE 1672
L+ E + L E EE L ++QE E+ + HD + + EE
Sbjct: 889 LQAETE--------LCAEAEE------------LRARLTAKKQELEE-ICHDLEARVEEE 927
Query: 1673 EQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLR 1732
E+ Q Q +++ + +E E+QL +E R+ LQ E+ +L++
Sbjct: 928 EERCQ---HLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKK--------- 975
Query: 1733 QETEQEQLRRQERYRKILEEEQLRPER-EEQQLRRQERDRKFREEEQLRQERE------E 1785
E+EQ+ +++ K+ +E++L +R E E + K + +L+ + E E
Sbjct: 976 --LEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLE 1033
Query: 1786 QQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQY 1845
++LR +E R+ E+ + + E + L Q + + + E ++QL ++E+ L+
Sbjct: 1034 ERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQA---ALA 1090
Query: 1846 RAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGE 1900
R EE+ A + + ++ +EL + + E + L E R + E+Q+ R +GE
Sbjct: 1091 RVEEEAAQKNMALKKIREL-----ESQISELQEDLESERASRNKAEKQK-RDLGE 1139
Score = 40.8 bits (94), Expect = 0.013
Identities = 40/148 (27%), Positives = 72/148 (48%), Gaps = 10/148 (6%)
Query: 1763 QLRRQERDRKFREEEQLRQ-EREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKY 1821
+LR + R F + + L Q R+E+++ ++E + E+QL E ++ Q
Sbjct: 821 KLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQS---- 876
Query: 1822 RWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERER--K 1879
+ E+LQL+EQ L+ E + AEE A ++E +E+ + E + +E ER
Sbjct: 877 QLMAEKLQLQEQ---LQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQH 933
Query: 1880 LREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
L+ E + QQ ++ Q+ E +S K
Sbjct: 934 LQAEKKKMQQNIQELEEQLEEEESARQK 961
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 215 bits (547), Expect = 4e-55
Identities = 258/1127 (22%), Positives = 508/1127 (45%), Gaps = 118/1127 (10%)
Query: 286 LRRERQEEEQQ--QQRLRREQQLRRKQEEERREQQEERREQQERRE--QQEERREQQLRR 341
L+ RQEEE Q + L++ ++ ++K E E +E +++ + E + Q++ + E +L
Sbjct: 845 LQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYA 904
Query: 342 EQEERREQQLRREQE-EERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQ 400
E EE R + ++QE EE + R +EEE R QQL+ E++ +Q L E+QL E+
Sbjct: 905 EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEA 964
Query: 401 LRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR----EQRLKREQEERRD 456
R++ QL + + ++L E + +Q + +++ E R L E+E+ ++
Sbjct: 965 ARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN 1024
Query: 457 W--LKREEETERHEQE-RRKQQLKRDQEEERRERWLKLEEEERRE-------QQERREQQ 506
LK + E+ E E R K++ K QE E+ +R L+ + + E Q + Q
Sbjct: 1025 LTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQ 1084
Query: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL-LKREEEKRLEQERRE- 564
L +++EE + + +E + L+ ++L + +E L +R + E+++R+
Sbjct: 1085 LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDL 1144
Query: 565 ----QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620
+ LK E E+ D ++E R KREQE + ++ EE R + + +E R
Sbjct: 1145 GEELEALKTELEDTLDSTATQQE----LRAKREQEVTVLKKALDEET-RSHEAQVQEMRQ 1199
Query: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQ-RLKREHEEE 679
K + EE +QL EQ +R + L + +Q ++ E L Q + + EH+++
Sbjct: 1200 KHAQAVEELTEQL----EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKK 1255
Query: 680 RREQELAE-----EEQEQARERIKSRIPKWQWQLES------EADARQSKVYS-----RP 723
+ E ++ E + E+AR + ++ K Q ++ES EA+ + K+
Sbjct: 1256 KLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1315
Query: 724 RKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQR 783
+ Q+ Q QE+ ++ ++L+ EEER Q Q +E + +A++ ER
Sbjct: 1316 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDE-------EMEAKQNLERHIST 1368
Query: 784 LSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRR 843
L+ QL +++ ++ E E+ ++R Q+ Q+ E+ +
Sbjct: 1369 LNI----------QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1418
Query: 844 ERAQ-QLQEEEDGLQEDQERRR---SQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQL 899
E+ + +LQ+E D L D + +R S +++ +K+ L EE+ + E+
Sbjct: 1419 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKN------ISSKYADERD 1472
Query: 900 RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959
R E + ++E + L + + +E R + L+ E E L+ + + + +
Sbjct: 1473 RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK 1532
Query: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR------EEREKRRR 1013
++ + Q +E + EE E + + K R E +Q + Q R E+ E++RR
Sbjct: 1533 SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1592
Query: 1014 QEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRR 1073
Q + + + EL+ E +Q K++L E ++ E Q + + G E ++
Sbjct: 1593 QLQRQLHEYETELEDERKQRALAAAAKKKL---EGDLKDLE--LQADSAIKGREEAIKQL 1647
Query: 1074 QELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRR 1133
++L+ Q K+ + + E+ + R+E ++ ++ E +L Q +E L ER R++
Sbjct: 1648 RKLQAQ-MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER-ARKQ 1705
Query: 1134 QELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQ 1193
+LE++ EE + ++ EKRR + Q EE E +Q + + + K Q
Sbjct: 1706 ADLEKEELAEELASSLSGRNALQD-EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1764
Query: 1194 ERERQYRE---EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQF 1250
+ E+ E E ++ R + E Q +L+ + E E AV+ +
Sbjct: 1765 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH-EMEGAVKSKFKSTIAALEAKI 1823
Query: 1251 RQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE-------EEQLEREE 1303
QLE+ EQ+ R+++ + +Q+D+ E E ++ +
Sbjct: 1824 AQLEEQV---------------EQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY 1868
Query: 1304 QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE 1350
+++A++ + + ++ K+ L E EE +R RK + E E E
Sbjct: 1869 KEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNE 1915
Score = 205 bits (521), Expect = 4e-52
Identities = 262/1149 (22%), Positives = 527/1149 (45%), Gaps = 126/1149 (10%)
Query: 833 FLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAK 892
F + + LQ + +++Q +ED LQ+ +ER++ E +L+E ++ K
Sbjct: 838 FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAEN--------ELKELEQKHSQLTEEK 889
Query: 893 PALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRR 952
LQEQL+ E +L E EE R +K+ E E++ E E L EE ++ +
Sbjct: 890 NLLQEQLQAETELYAEAEEMRVRLAAKKQ----------ELEEILHEMEARLEEEEDRGQ 939
Query: 953 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1012
+ + ER+ + L +E+ L EE R++ + EK E + + E+E L+ +++ +
Sbjct: 940 QLQAERKKMAQQMLDLEEQ--LEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKL 997
Query: 1013 RQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRR 1072
+E + + +L L EE EK + + + + E + + E +L EE+
Sbjct: 998 SKERKLLEERISDLTTN----LAEEEEKAKNLTKLKN-KHESMISELEVRLKKEEKS--- 1049
Query: 1073 RQELERQYRK-EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE----EEQLLREE 1127
RQELE+ RK E + EQ+ + + + + + + ++EEELQ ++++ ++
Sbjct: 1050 RQELEKLKRKLEGDASDFHEQIA--DLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1107
Query: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRR---QELERQYREEEEL-----QQE 1179
++ +ELE + +E + E+ R + EK++R +ELE E E+ Q+
Sbjct: 1108 NALKKIRELEGHISDLQE-DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQ 1166
Query: 1180 EEQLLREEQ----EKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV 1235
E + RE++ +K E R + + + RQK Q + ++ + Q++ K N
Sbjct: 1167 ELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE---QFKRAKANLD 1223
Query: 1236 RDNKVYCKGREN--EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHF 1293
++ + K + + R L ++ ++ L+ + E Q + + ER R + D+
Sbjct: 1224 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1283
Query: 1294 PEEEQLER-------------EEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE 1340
+ ++E + K+ + Q+ ++LL+EE +K R+ E
Sbjct: 1284 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1343
Query: 1341 EEQLLQER-EEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR-QERERKFLKEEQQ 1398
E LQ++ +E+ +Q +R ++ + +K + + +E +++F KE +
Sbjct: 1344 ERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN 1403
Query: 1399 LRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQE 1458
L Q E+ D K + + +L ++ D + Q+ E+K + +Q L +E
Sbjct: 1404 LTQQYEEKAAAYD---KLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1460
Query: 1459 RH--RKFREE----EQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQE 1512
++ K+ +E E +E+E + L + LE +++L R + K ++L S +
Sbjct: 1461 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSK 1520
Query: 1513 PERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQL 1572
+ + +H ++ ++ L+ + + + + Q + + + E+ +LR E Q L
Sbjct: 1521 DD-----VGKNVHELEKSKRALETQME---EMKTQLEELEDELQATEDAKLRLEVNMQAL 1572
Query: 1573 SRQ-ERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQER 1631
Q ERD + R E+ + +R++ +R+ E E +L + Q+ L +K D + L+ +
Sbjct: 1573 KGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ 1632
Query: 1632 EEQQLH-RQERDRKFLEEEPQLRRQERE-QQLRHDRDRKF---REEEQLLQEGE------ 1680
+ + R+E ++ + + Q++ +RE + R RD F +E E+ + E
Sbjct: 1633 ADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQL 1692
Query: 1681 EQQLRRQERDRKFREEEQQLRRQERE-----RKFLQEEQ---QLRRQELERKFREEEQLR 1732
++ L ER RK + E++ +E R LQ+E+ + R +LE + EEEQ
Sbjct: 1693 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL-EEEQGN 1751
Query: 1733 QETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQE 1792
E +++R+ + + L E L ER Q R + R+ ++LR + E + +
Sbjct: 1752 MEAMSDRVRKATQQAEQLSNE-LATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKS 1810
Query: 1793 S--------DRKFRE-EEQLRQEREEQQLRPQ---QRDGKYRWEEEQLQLEEQEQRLRQE 1840
+ K + EEQ+ QE E+Q + Q+D K + E LQ+E++ + Q
Sbjct: 1811 KFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK--EILLQVEDERKMAEQY 1868
Query: 1841 RDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGE 1900
+++ AE+ A ++ +R+ +E EEE +R RKL+ E + E R+V
Sbjct: 1869 KEQ---AEKGNARVKQLKRQLEEA--EEESQRINANRRKLQRELDEATESNEAMGREVNA 1923
Query: 1901 IKSQEGKGH 1909
+KS+ +G+
Sbjct: 1924 LKSKLRRGN 1932
Score = 201 bits (510), Expect = 8e-51
Identities = 260/1122 (23%), Positives = 515/1122 (45%), Gaps = 125/1122 (11%)
Query: 91 QATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAE 150
Q T +EE +A KE LQ + +E Q++ E ++LE++ Q +K QE+ AE
Sbjct: 846 QVTRQEEEMQA----KEDELQ--KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 899
Query: 151 GEEQSEKQE-RLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHET----EEFP 205
E +E +E R+ +++ EE+ + + E EE R ++ Q + K + EE
Sbjct: 900 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL 959
Query: 206 DEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265
+EE+ R++L K E + ++ E + V ++ K L KE + L+E
Sbjct: 960 EEEEAARQKL--QLEKVTAEAKIKKLEDEILVMDDQNNK--------LSKERKLLEERIS 1009
Query: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ---EERR 322
L EEEE+ + L + + + E E + RL++E++ R++ E+ +R+ + +
Sbjct: 1010 DLTTNLAEEEEKAKNLTKLKNKHESMISE-LEVRLKKEEKSRQELEKLKRKLEGDASDFH 1068
Query: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQ 382
EQ + Q + QL +++EE + R + E ++ L++ +E E L+ +
Sbjct: 1069 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLD 1128
Query: 383 LRREQQLRREQQLRREQQLRREQQLRREQQL-----RREQQLRREQQ---LRREQEEERH 434
R + + E+Q R + + E L ++E + +REQ+ L++ +EE
Sbjct: 1129 SERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEE-- 1186
Query: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQ-ERRKQQLKRDQEEERRER------ 487
+ HE + +E R K Q EE TE+ EQ +R K L ++++ +E
Sbjct: 1187 TRSHEAQVQEMRQKHAQAV-------EELTEQLEQFKRAKANLDKNKQTLEKENADLAGE 1239
Query: 488 -----WLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
K E E ++++ E + Q+L+ + + R + ++ +LQ + S + E
Sbjct: 1240 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEA 1299
Query: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRD---QLLKREEERR--QQRLKREQE-- 595
E + +L K + + ++ L+ E ++ + +L + EEER Q +L E E
Sbjct: 1300 EGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAK 1359
Query: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ--EERRQQQLRREQQE 653
+ LE+ + ++ + +++ + E EE +++ K E ++ ++ ++ E
Sbjct: 1360 QNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLE 1419
Query: 654 RREQRLKREEEE-----ERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQL 708
+ + RL++E ++ + Q + +++R+ +L EE + I S+ + +
Sbjct: 1420 KTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE-----KNISSKYADERDRA 1474
Query: 709 ESEADARQSKVYSRPRK-QEGQRRRQEQEEKRRRRESELQ------------WQEEERAH 755
E+EA +++K S R +E ++E E + ++E++ E E++
Sbjct: 1475 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1534
Query: 756 R--QQQEEEQRRDFTWQWQAEEKSERGRQRLSAR-PPLREQRERQLRA-----EERQQRE 807
R + Q EE + + +E + RL L+ Q ER L+A EE++++
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1594
Query: 808 QRFLPE-EEEKEQRRRQR-------REREKELQFLE--EEEQLQRRERA-QQLQEEEDGL 856
QR L E E E E R+QR ++ E +L+ LE + ++ RE A +QL++ + +
Sbjct: 1595 QRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQM 1654
Query: 857 QEDQERRRSQEQRRDQKWRWQLEEERKRRR-----HTLYAKPALQEQLRKEQQLLQEE-E 910
++ Q RD+ + E E+K + L A E+ RK+ L +EE
Sbjct: 1655 KDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA 1714
Query: 911 EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKE 970
EEL + Q+++R R E ++ Q EE+L E+ +R R K Q+
Sbjct: 1715 EELASSLSGRNALQDEKR--RLEARIAQLEEELEEEQGNMEAMSDRVR------KATQQA 1766
Query: 971 EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKD-ELQQE 1029
EQL E +R ++ + R++ E Q +E + E E + +++ + ++ Q
Sbjct: 1767 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1826
Query: 1030 EEQLLREEREK----RRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
EEQ+ +E REK + L++++++ + E LQ E+E+ + E+ + + + R + + +
Sbjct: 1827 EEQVEQEAREKQAATKSLKQKDKKLK-EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQ 1885
Query: 1086 LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127
L++ EE+ R +R+ Q + E E E L+ +
Sbjct: 1886 LEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1927
Score = 200 bits (508), Expect = 1e-50
Identities = 262/1108 (23%), Positives = 513/1108 (46%), Gaps = 155/1108 (13%)
Query: 213 RELLELRR-----KGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR 267
+ LL++ R + +E++ Q+ +ERQ + E E KE ++ + L EE+ L +E+ Q
Sbjct: 842 KPLLQVTRQEEEMQAKEDELQKTKERQQKA--ENELKELEQKHSQL-TEEKNLLQEQLQA 898
Query: 268 QRELQEEEEQLR------KLERQELRRER----QEEEQQQQRLRREQQLRRKQEEERREQ 317
+ EL E E++R K E +E+ E +EEE + Q+L+ E++ +Q + EQ
Sbjct: 899 ETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ 958
Query: 318 QEERREQQERREQQEERREQQLRREQEE-----RREQQLRREQE--EERREQQLRREQEE 370
EE +++ + ++ E ++++ ++E + +L +E++ EER EE
Sbjct: 959 LEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1018
Query: 371 ERREQQLRREQQLRREQQLRREQQLRREQQLRRE-QQLRREQQ---LRREQQLRREQQLR 426
E + + L + + E +L++E++ R+E ++L+R+ + +Q+ Q
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078
Query: 427 REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRE 486
E + + +++ E + RL E ++ + LK+ E E H + L+ D + ER
Sbjct: 1079 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISD-----LQEDLDSERAA 1133
Query: 487 RWLKLEEEERREQQERREQQLRREQEE-------RREQRLKRQEEEERLQQRLRSE---- 535
R E+++R+ E E L+ E E+ ++E R KR++E L++ L E
Sbjct: 1134 R--NKAEKQKRDLGEELE-ALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH 1190
Query: 536 ----QQLRREQEERREQLLKREEE---KRLEQERREQRLKREQEERRDQL-----LKREE 583
Q++R++ + E+L ++ E+ + ++ +Q L++E + +L K+E
Sbjct: 1191 EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEV 1250
Query: 584 ERRQQRLKREQEERLE-----QRLKRE---EVERLEQE---------ERREQRLKREEPE 626
E ++++L+ + +E +R + E +V +L+ E E + +K +
Sbjct: 1251 EHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1310
Query: 627 EERRQQLLKSEE--QEERRQQ-----QLRREQQERREQRLKREEEEERLEQRLKRE---- 675
QL ++E QEE RQ+ +LR+ ++ER + + +EE E +Q L+R
Sbjct: 1311 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME-AKQNLERHISTL 1369
Query: 676 ----HEEERREQELAE--EEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ--- 726
+ +++ Q+ A E E+ ++R + I Q E +A A ++ R Q
Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL 1429
Query: 727 -------EGQRRRQEQEEKRRRRESELQWQEE----------ERAHRQQQEEEQR----- 764
+ QR+ EK++R+ +L +E+ +RA + +E+E +
Sbjct: 1430 DDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLA 1489
Query: 765 RDFTWQWQAEEKSERGRQRLSAR-PPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQ 823
R +A+E+ ER + L A L ++ + ++ +R L E + E+ + Q
Sbjct: 1490 RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL--ETQMEEMKTQ 1547
Query: 824 RREREKELQFLEEEE-QLQRRERAQQLQEEED--GLQEDQERRRSQEQRRDQKWRWQLEE 880
E E ELQ E+ + +L+ +A + Q E D E E +R Q QR+ ++ +LE+
Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELED 1607
Query: 881 ERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEE 940
ERK+R AK L+ L+ + LQ + REE K+ R+ Q + ++ Q + E+
Sbjct: 1608 ERKQRALAAAAKKKLEGDLKDLE--LQADSAIKGREEAIKQLRKLQAQM--KDFQRELED 1663
Query: 941 EQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEE 1000
+ R+E ++ ++ + L Q +E L E + R++ E+EEL +E
Sbjct: 1664 ARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE------RARKQADLEKEELAEEL 1717
Query: 1001 EQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEE 1060
L R + + R + + Q EE+L E+ + +R R+ ++ E E
Sbjct: 1718 ASSL-----SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1772
Query: 1061 EQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEE 1120
L ER T ++ E RQ + E +E L E + + + E ++ Q E
Sbjct: 1773 ---LATERSTAQKNESARQ--QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLE 1827
Query: 1121 EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE 1180
EQ+ +E REK+ + +Q + ++ +E LL+ E E++ + QY+E+ E
Sbjct: 1828 EQVEQEAREKQAATKSLKQ-----KDKKLKEILLQVEDERK----MAEQYKEQAEKGNAR 1878
Query: 1181 EQLLREEQEKRRQERERQYREEEELQRQ 1208
+ L+ + E+ +E +R +LQR+
Sbjct: 1879 VKQLKRQLEEAEEESQRINANRRKLQRE 1906
Score = 129 bits (324), Expect = 3e-29
Identities = 148/636 (23%), Positives = 295/636 (46%), Gaps = 75/636 (11%)
Query: 111 QDRRQEEDQRRFE--PRDRQLEEEPGQRRRQ------KRQEQERELAEGEEQ-SEKQERL 161
Q+ QEE +++ + RQLEEE + Q +Q ER ++ Q S+ +++L
Sbjct: 1321 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380
Query: 162 E---------QRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPD---EEQ 209
+ + ++R +E+ Q++ EE+ A ++L+ K +E D +
Sbjct: 1381 QDFASTVEALEEGKKRFQKEIENLTQQY---EEKAAAYDKLEKTKNRLQQELDDLVVDLD 1437
Query: 210 LRRRELLELRRKGREEKQQQRRER---------QDRVFQEEEEKEWRKRETVLRKEEEKL 260
+R+ + L +K R+ Q E+ +DR E EKE K ++ R EE L
Sbjct: 1438 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE-TKALSLARALEEAL 1496
Query: 261 QEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE 320
+ +E EL+ + L K E ++L + + + L + ++ Q EE + Q EE
Sbjct: 1497 EAKE-----ELERTNKML-KAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1550
Query: 321 RREQQERREQQEERREQQLRREQEE-RREQQLRREQEEERREQQLRREQEEERREQQLRR 379
++ + E + R E ++ + + R+ Q R EQ EE+R Q R+ E E + R+
Sbjct: 1551 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1610
Query: 380 EQQLRREQQLRREQQLRREQQLRREQQLR-REQQLRREQQLRREQQ-LRREQEEERHEQK 437
++ L + + E L+ + +L+ + ++ RE+ +++ ++L+ + + +RE E+ R +
Sbjct: 1611 QRALAAAAKKKLEGDLK-DLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRD 1669
Query: 438 HEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK----LEE 493
++ K+ + D ++ +E+ E+ R++ L++++ E L L++
Sbjct: 1670 EIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQD 1729
Query: 494 EERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKRE 553
E+RR E R QL E EE Q E + R+R Q Q E+ L E
Sbjct: 1730 EKRR--LEARIAQLEEELEEE-------QGNMEAMSDRVRKATQ----QAEQLSNELATE 1776
Query: 554 EEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQE 613
+ E Q+L+R+ +E R +L E E + + LE ++ + E E++EQE
Sbjct: 1777 RSTAQKNESARQQLERQNKELRSKL--HEMEGAVKSKFKSTIAALEAKIAQLE-EQVEQE 1833
Query: 614 ERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKR--------EEEE 665
R +Q + +++++ + + + ++ER+ + +EQ E+ R+K+ EEE
Sbjct: 1834 AREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEES 1893
Query: 666 ERLE---QRLKREHEEERREQELAEEEQEQARERIK 698
+R+ ++L+RE +E E E + +++
Sbjct: 1894 QRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 109 bits (272), Expect = 3e-23
Identities = 105/487 (21%), Positives = 231/487 (47%), Gaps = 30/487 (6%)
Query: 116 EEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWR 175
E D+ E R+++ + R ++ E + EL E++ K + E D +++ +
Sbjct: 1470 ERDRAEAEAREKETKALSLARALEEALEAKEEL----ERTNKMLKAEMEDLVSSKDDVGK 1525
Query: 176 QRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQD 235
E ++ +RA E Q++ K + EE DE Q L L + K Q R+ Q
Sbjct: 1526 NVHELEK--SKRALETQMEEMKT-QLEELEDELQATEDAKLRLEVNMQALKGQFERDLQA 1582
Query: 236 RVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR------QRELQEEEEQLRKLERQELRRE 289
R Q EE++ +R+ L + E +L++E QR +++L+ + + L +L+ +
Sbjct: 1583 RDEQNEEKRRQLQRQ--LHEYETELEDERKQRALAAAAKKKLEGDLKDL-ELQADSAIKG 1639
Query: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQ 349
R+E +Q ++L+ + + +++ E+ R ++E + E++ + E L + QE+
Sbjct: 1640 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1699
Query: 350 QLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR-EQQLRREQQLRREQQLR 408
+ R+Q + +E+ L E + ++++ R E ++ + E++L EQ R
Sbjct: 1700 ERARKQADLEKEE-LAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1758
Query: 409 REQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHE 468
+ ++ +QL E R ++ + + ER+ + L+ + E +K + ++
Sbjct: 1759 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1818
Query: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 528
E + QL+ E+E RE K + +Q++++ +++ + E+ R+ + +E+ E+
Sbjct: 1819 LEAKIAQLEEQVEQEARE---KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1875
Query: 529 QQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQ 588
R++ QL+R+ EE EE +R+ RR+ + + ++ ++ + RE +
Sbjct: 1876 NARVK---QLKRQLEE------AEEESQRINANRRKLQRELDEATESNEAMGREVNALKS 1926
Query: 589 RLKREQE 595
+L+R E
Sbjct: 1927 KLRRGNE 1933
Score = 107 bits (267), Expect = 1e-22
Identities = 131/594 (22%), Positives = 267/594 (44%), Gaps = 65/594 (10%)
Query: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRK 1415
+ERD K + + Q R +L + +RQ++ + Q C + R
Sbjct: 780 EERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAM--KVIQRNCAAYLKLRNWQWWRL 837
Query: 1416 FREEEQ--QLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE- 1472
F + + Q++RQE + + +E+E Q + +ER++K E ++L Q +H + EE+ LLQE
Sbjct: 838 FTKVKPLLQVTRQEEEMQAKEDELQ-KTKERQQKAENELKELEQ-KHSQLTEEKNLLQEQ 895
Query: 1473 -REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR 1531
+ E +L+ + + + ++QE + E E R +E E + ++ Q R++ +
Sbjct: 896 LQAETELYAEAEE---MRVRLAAKKQELEEILHEMEARLEEEEDR--GQQLQAERKKMAQ 950
Query: 1532 KFLQEEQQLRRQERGQQRRQ------DRDRKFREEEQLRQEREEQQLSRQERDRKFRLEE 1585
+ L E+QL +E +Q+ Q + K E+E L + + +LS++ + + R+ +
Sbjct: 951 QMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1010
Query: 1586 QKVRRQEQERKFMEDEQQLRRQE---GQQQLRQERDRKFREDEQLLQ---EREEQQLHRQ 1639
E+E K + + E + ++R +++ K R++ + L+ E + H Q
Sbjct: 1011 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1070
Query: 1640 ERD--RKFLEEEPQLRRQEREQQLRHDR-DRKFREEEQLLQEGEEQQLRRQERDRKFREE 1696
D + E + QL ++E E Q R D + ++ L++ E + + E
Sbjct: 1071 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1130
Query: 1697 EQQLRRQERERKFLQEEQQLRRQELERKF---REEEQLRQETEQEQLRRQERYRKILEEE 1753
+ E++++ L EE + + ELE +++LR + EQE +K L+EE
Sbjct: 1131 RAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQE----VTVLKKALDEE 1186
Query: 1754 QLRPEREEQQLRRQERDRKFREEEQLRQ--------EREEQQLRSQESD----------- 1794
E + Q++R++ EQL Q ++ +Q L + +D
Sbjct: 1187 TRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQA 1246
Query: 1795 RKFREEEQLRQEREEQQLRPQQRDGKY-------RWEEEQLQLEEQEQRLRQERDRQYRA 1847
++ E ++ + E + Q+L+ + DG+ + + Q ++E L + + +
Sbjct: 1247 KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKL 1306
Query: 1848 EEQFATQEKSRREEQELWQEEEQKRR--QERERKLREEH--IRRQQKEEQRHRQ 1897
+ A+ ++ QEL QEE +++ + R+L EE ++ Q EE +Q
Sbjct: 1307 AKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1360
Score = 89.7 bits (221), Expect = 2e-17
Identities = 97/447 (21%), Positives = 211/447 (47%), Gaps = 38/447 (8%)
Query: 1507 ELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE 1566
++ QE E + E+E Q ++++Q+ E +L+ E Q+ Q + K +EQL+ E
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKA----ENELKELE--QKHSQLTEEKNLLQEQLQAE 899
Query: 1567 REEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQ-QQLRQERDRKFREDE 1625
E L + + + RL +K QE E E E +L +E + QQL+ ER + ++
Sbjct: 900 TE---LYAEAEEMRVRLAAKK---QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 953
Query: 1626 QLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR 1685
L ++ EE++ RQ+ + + E ++++ E E + D++ K +E +LL+E R
Sbjct: 954 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEE------R 1007
Query: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQ-- 1743
+ EEE++ + + L+ + + ELE + ++EE+ RQE E+ + + +
Sbjct: 1008 ISDLTTNLAEEEEKAKNLTK----LKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1063
Query: 1744 -ERYRKILEEEQLRPEREEQQLRRQERDRK---FREEEQLRQEREE-QQLRSQESDRKFR 1798
+ + + + Q + + QL ++E + + R ++++ Q+ +++R E
Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDL 1123
Query: 1799 EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSR 1858
+E+ + + Q+RD E + +LE+ +++ + + E++ +K+
Sbjct: 1124 QEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKAL 1183
Query: 1859 REEQELWQEEEQKRRQERERKLRE-----EHIRRQQKEEQRHRQVGEIKSQEGKGHGRLL 1913
EE + + Q+ RQ+ + + E E +R + +++Q E ++ + G R+L
Sbjct: 1184 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1243
Query: 1914 EPGTHQFASVPVRSSPLYEYIQEQRSQ 1940
+ V + L +QE +S+
Sbjct: 1244 GQAKQE---VEHKKKKLEAQVQELQSK 1267
Score = 65.1 bits (157), Expect = 6e-10
Identities = 64/274 (23%), Positives = 126/274 (45%), Gaps = 31/274 (11%)
Query: 1643 RKFLEEEP--QLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQL 1700
R F + +P Q+ RQE E Q + D +K +E +Q + E + +++ + EE+ L
Sbjct: 836 RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQ---KAENELKELEQKHSQLTEEKNLL 892
Query: 1701 RRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPERE 1760
+ Q + L E + R L K +E E++ E E ++R +QL+ ER+
Sbjct: 893 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDR------GQQLQAERK 946
Query: 1761 EQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGK 1820
+ + + + + EEE RQ+ + +++ ++ +K E+E L + + +L +++ +
Sbjct: 947 KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL-EDEILVMDDQNNKLSKERKLLE 1005
Query: 1821 YRWEEEQLQLEEQEQRLRQERDRQYRAEEQFAT-------QEKSRREEQELWQEEEQKRR 1873
R + L E+E++ + + + E + +EKSR+E ++L KR+
Sbjct: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKL------KRK 1059
Query: 1874 QERERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
E + E I Q Q+ E+K Q K
Sbjct: 1060 LEGDASDFHEQIADLQ------AQIAELKMQLAK 1087
Score = 34.3 bits (77), Expect = 1.2
Identities = 22/107 (20%), Positives = 48/107 (44%), Gaps = 19/107 (17%)
Query: 1821 YRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKL 1880
++W +++ Q RQE + Q + +E T+E+ ++ E EL + E++ + E+ L
Sbjct: 832 WQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNL 891
Query: 1881 REEHI-------------------RRQQKEEQRHRQVGEIKSQEGKG 1908
+E + ++Q+ EE H ++ +E +G
Sbjct: 892 LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 938
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 215 bits (547), Expect = 4e-55
Identities = 258/1127 (22%), Positives = 508/1127 (45%), Gaps = 118/1127 (10%)
Query: 286 LRRERQEEEQQ--QQRLRREQQLRRKQEEERREQQEERREQQERRE--QQEERREQQLRR 341
L+ RQEEE Q + L++ ++ ++K E E +E +++ + E + Q++ + E +L
Sbjct: 852 LQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYA 911
Query: 342 EQEERREQQLRREQE-EERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQ 400
E EE R + ++QE EE + R +EEE R QQL+ E++ +Q L E+QL E+
Sbjct: 912 EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEA 971
Query: 401 LRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR----EQRLKREQEERRD 456
R++ QL + + ++L E + +Q + +++ E R L E+E+ ++
Sbjct: 972 ARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN 1031
Query: 457 W--LKREEETERHEQE-RRKQQLKRDQEEERRERWLKLEEEERRE-------QQERREQQ 506
LK + E+ E E R K++ K QE E+ +R L+ + + E Q + Q
Sbjct: 1032 LTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQ 1091
Query: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL-LKREEEKRLEQERRE- 564
L +++EE + + +E + L+ ++L + +E L +R + E+++R+
Sbjct: 1092 LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDL 1151
Query: 565 ----QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620
+ LK E E+ D ++E R KREQE + ++ EE R + + +E R
Sbjct: 1152 GEELEALKTELEDTLDSTATQQE----LRAKREQEVTVLKKALDEET-RSHEAQVQEMRQ 1206
Query: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQ-RLKREHEEE 679
K + EE +QL EQ +R + L + +Q ++ E L Q + + EH+++
Sbjct: 1207 KHAQAVEELTEQL----EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKK 1262
Query: 680 RREQELAE-----EEQEQARERIKSRIPKWQWQLES------EADARQSKVYS-----RP 723
+ E ++ E + E+AR + ++ K Q ++ES EA+ + K+
Sbjct: 1263 KLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1322
Query: 724 RKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQR 783
+ Q+ Q QE+ ++ ++L+ EEER Q Q +E + +A++ ER
Sbjct: 1323 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDE-------EMEAKQNLERHIST 1375
Query: 784 LSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRR 843
L+ QL +++ ++ E E+ ++R Q+ Q+ E+ +
Sbjct: 1376 LNI----------QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1425
Query: 844 ERAQ-QLQEEEDGLQEDQERRR---SQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQL 899
E+ + +LQ+E D L D + +R S +++ +K+ L EE+ + E+
Sbjct: 1426 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKN------ISSKYADERD 1479
Query: 900 RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959
R E + ++E + L + + +E R + L+ E E L+ + + + +
Sbjct: 1480 RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK 1539
Query: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR------EEREKRRR 1013
++ + Q +E + EE E + + K R E +Q + Q R E+ E++RR
Sbjct: 1540 SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1599
Query: 1014 QEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRR 1073
Q + + + EL+ E +Q K++L E ++ E Q + + G E ++
Sbjct: 1600 QLQRQLHEYETELEDERKQRALAAAAKKKL---EGDLKDLE--LQADSAIKGREEAIKQL 1654
Query: 1074 QELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRR 1133
++L+ Q K+ + + E+ + R+E ++ ++ E +L Q +E L ER R++
Sbjct: 1655 RKLQAQ-MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER-ARKQ 1712
Query: 1134 QELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQ 1193
+LE++ EE + ++ EKRR + Q EE E +Q + + + K Q
Sbjct: 1713 ADLEKEELAEELASSLSGRNALQD-EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1771
Query: 1194 ERERQYRE---EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQF 1250
+ E+ E E ++ R + E Q +L+ + E E AV+ +
Sbjct: 1772 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH-EMEGAVKSKFKSTIAALEAKI 1830
Query: 1251 RQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE-------EEQLEREE 1303
QLE+ EQ+ R+++ + +Q+D+ E E ++ +
Sbjct: 1831 AQLEEQV---------------EQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY 1875
Query: 1304 QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE 1350
+++A++ + + ++ K+ L E EE +R RK + E E E
Sbjct: 1876 KEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNE 1922
Score = 205 bits (521), Expect = 4e-52
Identities = 262/1149 (22%), Positives = 527/1149 (45%), Gaps = 126/1149 (10%)
Query: 833 FLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAK 892
F + + LQ + +++Q +ED LQ+ +ER++ E +L+E ++ K
Sbjct: 845 FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAEN--------ELKELEQKHSQLTEEK 896
Query: 893 PALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRR 952
LQEQL+ E +L E EE R +K+ E E++ E E L EE ++ +
Sbjct: 897 NLLQEQLQAETELYAEAEEMRVRLAAKKQ----------ELEEILHEMEARLEEEEDRGQ 946
Query: 953 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1012
+ + ER+ + L +E+ L EE R++ + EK E + + E+E L+ +++ +
Sbjct: 947 QLQAERKKMAQQMLDLEEQ--LEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKL 1004
Query: 1013 RQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRR 1072
+E + + +L L EE EK + + + + E + + E +L EE+
Sbjct: 1005 SKERKLLEERISDLTTN----LAEEEEKAKNLTKLKN-KHESMISELEVRLKKEEKS--- 1056
Query: 1073 RQELERQYRK-EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE----EEQLLREE 1127
RQELE+ RK E + EQ+ + + + + + + ++EEELQ ++++ ++
Sbjct: 1057 RQELEKLKRKLEGDASDFHEQIA--DLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1114
Query: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRR---QELERQYREEEEL-----QQE 1179
++ +ELE + +E + E+ R + EK++R +ELE E E+ Q+
Sbjct: 1115 NALKKIRELEGHISDLQE-DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQ 1173
Query: 1180 EEQLLREEQ----EKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV 1235
E + RE++ +K E R + + + RQK Q + ++ + Q++ K N
Sbjct: 1174 ELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE---QFKRAKANLD 1230
Query: 1236 RDNKVYCKGREN--EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHF 1293
++ + K + + R L ++ ++ L+ + E Q + + ER R + D+
Sbjct: 1231 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1290
Query: 1294 PEEEQLER-------------EEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE 1340
+ ++E + K+ + Q+ ++LL+EE +K R+ E
Sbjct: 1291 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1350
Query: 1341 EEQLLQER-EEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR-QERERKFLKEEQQ 1398
E LQ++ +E+ +Q +R ++ + +K + + +E +++F KE +
Sbjct: 1351 ERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN 1410
Query: 1399 LRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQE 1458
L Q E+ D K + + +L ++ D + Q+ E+K + +Q L +E
Sbjct: 1411 LTQQYEEKAAAYD---KLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1467
Query: 1459 RH--RKFREE----EQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQE 1512
++ K+ +E E +E+E + L + LE +++L R + K ++L S +
Sbjct: 1468 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSK 1527
Query: 1513 PERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQL 1572
+ + +H ++ ++ L+ + + + + Q + + + E+ +LR E Q L
Sbjct: 1528 DD-----VGKNVHELEKSKRALETQME---EMKTQLEELEDELQATEDAKLRLEVNMQAL 1579
Query: 1573 SRQ-ERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQER 1631
Q ERD + R E+ + +R++ +R+ E E +L + Q+ L +K D + L+ +
Sbjct: 1580 KGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ 1639
Query: 1632 EEQQLH-RQERDRKFLEEEPQLRRQERE-QQLRHDRDRKF---REEEQLLQEGE------ 1680
+ + R+E ++ + + Q++ +RE + R RD F +E E+ + E
Sbjct: 1640 ADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQL 1699
Query: 1681 EQQLRRQERDRKFREEEQQLRRQERE-----RKFLQEEQ---QLRRQELERKFREEEQLR 1732
++ L ER RK + E++ +E R LQ+E+ + R +LE + EEEQ
Sbjct: 1700 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL-EEEQGN 1758
Query: 1733 QETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQE 1792
E +++R+ + + L E L ER Q R + R+ ++LR + E + +
Sbjct: 1759 MEAMSDRVRKATQQAEQLSNE-LATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKS 1817
Query: 1793 S--------DRKFRE-EEQLRQEREEQQLRPQ---QRDGKYRWEEEQLQLEEQEQRLRQE 1840
+ K + EEQ+ QE E+Q + Q+D K + E LQ+E++ + Q
Sbjct: 1818 KFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK--EILLQVEDERKMAEQY 1875
Query: 1841 RDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGE 1900
+++ AE+ A ++ +R+ +E EEE +R RKL+ E + E R+V
Sbjct: 1876 KEQ---AEKGNARVKQLKRQLEEA--EEESQRINANRRKLQRELDEATESNEAMGREVNA 1930
Query: 1901 IKSQEGKGH 1909
+KS+ +G+
Sbjct: 1931 LKSKLRRGN 1939
Score = 201 bits (510), Expect = 8e-51
Identities = 260/1122 (23%), Positives = 515/1122 (45%), Gaps = 125/1122 (11%)
Query: 91 QATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAE 150
Q T +EE +A KE LQ + +E Q++ E ++LE++ Q +K QE+ AE
Sbjct: 853 QVTRQEEEMQA----KEDELQ--KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 906
Query: 151 GEEQSEKQE-RLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHET----EEFP 205
E +E +E R+ +++ EE+ + + E EE R ++ Q + K + EE
Sbjct: 907 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL 966
Query: 206 DEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265
+EE+ R++L K E + ++ E + V ++ K L KE + L+E
Sbjct: 967 EEEEAARQKL--QLEKVTAEAKIKKLEDEILVMDDQNNK--------LSKERKLLEERIS 1016
Query: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ---EERR 322
L EEEE+ + L + + + E E + RL++E++ R++ E+ +R+ + +
Sbjct: 1017 DLTTNLAEEEEKAKNLTKLKNKHESMISE-LEVRLKKEEKSRQELEKLKRKLEGDASDFH 1075
Query: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQ 382
EQ + Q + QL +++EE + R + E ++ L++ +E E L+ +
Sbjct: 1076 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLD 1135
Query: 383 LRREQQLRREQQLRREQQLRREQQLRREQQL-----RREQQLRREQQ---LRREQEEERH 434
R + + E+Q R + + E L ++E + +REQ+ L++ +EE
Sbjct: 1136 SERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEE-- 1193
Query: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQ-ERRKQQLKRDQEEERRER------ 487
+ HE + +E R K Q EE TE+ EQ +R K L ++++ +E
Sbjct: 1194 TRSHEAQVQEMRQKHAQAV-------EELTEQLEQFKRAKANLDKNKQTLEKENADLAGE 1246
Query: 488 -----WLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
K E E ++++ E + Q+L+ + + R + ++ +LQ + S + E
Sbjct: 1247 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEA 1306
Query: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRD---QLLKREEERR--QQRLKREQE-- 595
E + +L K + + ++ L+ E ++ + +L + EEER Q +L E E
Sbjct: 1307 EGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAK 1366
Query: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ--EERRQQQLRREQQE 653
+ LE+ + ++ + +++ + E EE +++ K E ++ ++ ++ E
Sbjct: 1367 QNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLE 1426
Query: 654 RREQRLKREEEE-----ERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQL 708
+ + RL++E ++ + Q + +++R+ +L EE + I S+ + +
Sbjct: 1427 KTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE-----KNISSKYADERDRA 1481
Query: 709 ESEADARQSKVYSRPRK-QEGQRRRQEQEEKRRRRESELQ------------WQEEERAH 755
E+EA +++K S R +E ++E E + ++E++ E E++
Sbjct: 1482 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1541
Query: 756 R--QQQEEEQRRDFTWQWQAEEKSERGRQRLSAR-PPLREQRERQLRA-----EERQQRE 807
R + Q EE + + +E + RL L+ Q ER L+A EE++++
Sbjct: 1542 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1601
Query: 808 QRFLPE-EEEKEQRRRQR-------REREKELQFLE--EEEQLQRRERA-QQLQEEEDGL 856
QR L E E E E R+QR ++ E +L+ LE + ++ RE A +QL++ + +
Sbjct: 1602 QRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQM 1661
Query: 857 QEDQERRRSQEQRRDQKWRWQLEEERKRRR-----HTLYAKPALQEQLRKEQQLLQEE-E 910
++ Q RD+ + E E+K + L A E+ RK+ L +EE
Sbjct: 1662 KDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA 1721
Query: 911 EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKE 970
EEL + Q+++R R E ++ Q EE+L E+ +R R K Q+
Sbjct: 1722 EELASSLSGRNALQDEKR--RLEARIAQLEEELEEEQGNMEAMSDRVR------KATQQA 1773
Query: 971 EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKD-ELQQE 1029
EQL E +R ++ + R++ E Q +E + E E + +++ + ++ Q
Sbjct: 1774 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1833
Query: 1030 EEQLLREEREK----RRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
EEQ+ +E REK + L++++++ + E LQ E+E+ + E+ + + + R + + +
Sbjct: 1834 EEQVEQEAREKQAATKSLKQKDKKLK-EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQ 1892
Query: 1086 LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127
L++ EE+ R +R+ Q + E E E L+ +
Sbjct: 1893 LEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1934
Score = 200 bits (508), Expect = 1e-50
Identities = 262/1108 (23%), Positives = 513/1108 (46%), Gaps = 155/1108 (13%)
Query: 213 RELLELRR-----KGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR 267
+ LL++ R + +E++ Q+ +ERQ + E E KE ++ + L EE+ L +E+ Q
Sbjct: 849 KPLLQVTRQEEEMQAKEDELQKTKERQQKA--ENELKELEQKHSQL-TEEKNLLQEQLQA 905
Query: 268 QRELQEEEEQLR------KLERQELRRER----QEEEQQQQRLRREQQLRRKQEEERREQ 317
+ EL E E++R K E +E+ E +EEE + Q+L+ E++ +Q + EQ
Sbjct: 906 ETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ 965
Query: 318 QEERREQQERREQQEERREQQLRREQEE-----RREQQLRREQE--EERREQQLRREQEE 370
EE +++ + ++ E ++++ ++E + +L +E++ EER EE
Sbjct: 966 LEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1025
Query: 371 ERREQQLRREQQLRREQQLRREQQLRREQQLRRE-QQLRREQQ---LRREQQLRREQQLR 426
E + + L + + E +L++E++ R+E ++L+R+ + +Q+ Q
Sbjct: 1026 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1085
Query: 427 REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRE 486
E + + +++ E + RL E ++ + LK+ E E H + L+ D + ER
Sbjct: 1086 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISD-----LQEDLDSERAA 1140
Query: 487 RWLKLEEEERREQQERREQQLRREQEE-------RREQRLKRQEEEERLQQRLRSE---- 535
R E+++R+ E E L+ E E+ ++E R KR++E L++ L E
Sbjct: 1141 R--NKAEKQKRDLGEELE-ALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH 1197
Query: 536 ----QQLRREQEERREQLLKREEE---KRLEQERREQRLKREQEERRDQL-----LKREE 583
Q++R++ + E+L ++ E+ + ++ +Q L++E + +L K+E
Sbjct: 1198 EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEV 1257
Query: 584 ERRQQRLKREQEERLE-----QRLKRE---EVERLEQE---------ERREQRLKREEPE 626
E ++++L+ + +E +R + E +V +L+ E E + +K +
Sbjct: 1258 EHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1317
Query: 627 EERRQQLLKSEE--QEERRQQ-----QLRREQQERREQRLKREEEEERLEQRLKRE---- 675
QL ++E QEE RQ+ +LR+ ++ER + + +EE E +Q L+R
Sbjct: 1318 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME-AKQNLERHISTL 1376
Query: 676 ----HEEERREQELAE--EEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ--- 726
+ +++ Q+ A E E+ ++R + I Q E +A A ++ R Q
Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL 1436
Query: 727 -------EGQRRRQEQEEKRRRRESELQWQEE----------ERAHRQQQEEEQR----- 764
+ QR+ EK++R+ +L +E+ +RA + +E+E +
Sbjct: 1437 DDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLA 1496
Query: 765 RDFTWQWQAEEKSERGRQRLSAR-PPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQ 823
R +A+E+ ER + L A L ++ + ++ +R L E + E+ + Q
Sbjct: 1497 RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL--ETQMEEMKTQ 1554
Query: 824 RREREKELQFLEEEE-QLQRRERAQQLQEEED--GLQEDQERRRSQEQRRDQKWRWQLEE 880
E E ELQ E+ + +L+ +A + Q E D E E +R Q QR+ ++ +LE+
Sbjct: 1555 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELED 1614
Query: 881 ERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEE 940
ERK+R AK L+ L+ + LQ + REE K+ R+ Q + ++ Q + E+
Sbjct: 1615 ERKQRALAAAAKKKLEGDLKDLE--LQADSAIKGREEAIKQLRKLQAQM--KDFQRELED 1670
Query: 941 EQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEE 1000
+ R+E ++ ++ + L Q +E L E + R++ E+EEL +E
Sbjct: 1671 ARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE------RARKQADLEKEELAEEL 1724
Query: 1001 EQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEE 1060
L R + + R + + Q EE+L E+ + +R R+ ++ E E
Sbjct: 1725 ASSL-----SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1779
Query: 1061 EQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEE 1120
L ER T ++ E RQ + E +E L E + + + E ++ Q E
Sbjct: 1780 ---LATERSTAQKNESARQ--QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLE 1834
Query: 1121 EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE 1180
EQ+ +E REK+ + +Q + ++ +E LL+ E E++ + QY+E+ E
Sbjct: 1835 EQVEQEAREKQAATKSLKQ-----KDKKLKEILLQVEDERK----MAEQYKEQAEKGNAR 1885
Query: 1181 EQLLREEQEKRRQERERQYREEEELQRQ 1208
+ L+ + E+ +E +R +LQR+
Sbjct: 1886 VKQLKRQLEEAEEESQRINANRRKLQRE 1913
Score = 129 bits (324), Expect = 3e-29
Identities = 148/636 (23%), Positives = 295/636 (46%), Gaps = 75/636 (11%)
Query: 111 QDRRQEEDQRRFE--PRDRQLEEEPGQRRRQ------KRQEQERELAEGEEQ-SEKQERL 161
Q+ QEE +++ + RQLEEE + Q +Q ER ++ Q S+ +++L
Sbjct: 1328 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1387
Query: 162 E---------QRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPD---EEQ 209
+ + ++R +E+ Q++ EE+ A ++L+ K +E D +
Sbjct: 1388 QDFASTVEALEEGKKRFQKEIENLTQQY---EEKAAAYDKLEKTKNRLQQELDDLVVDLD 1444
Query: 210 LRRRELLELRRKGREEKQQQRRER---------QDRVFQEEEEKEWRKRETVLRKEEEKL 260
+R+ + L +K R+ Q E+ +DR E EKE K ++ R EE L
Sbjct: 1445 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE-TKALSLARALEEAL 1503
Query: 261 QEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE 320
+ +E EL+ + L K E ++L + + + L + ++ Q EE + Q EE
Sbjct: 1504 EAKE-----ELERTNKML-KAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1557
Query: 321 RREQQERREQQEERREQQLRREQEE-RREQQLRREQEEERREQQLRREQEEERREQQLRR 379
++ + E + R E ++ + + R+ Q R EQ EE+R Q R+ E E + R+
Sbjct: 1558 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1617
Query: 380 EQQLRREQQLRREQQLRREQQLRREQQLR-REQQLRREQQLRREQQ-LRREQEEERHEQK 437
++ L + + E L+ + +L+ + ++ RE+ +++ ++L+ + + +RE E+ R +
Sbjct: 1618 QRALAAAAKKKLEGDLK-DLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRD 1676
Query: 438 HEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK----LEE 493
++ K+ + D ++ +E+ E+ R++ L++++ E L L++
Sbjct: 1677 EIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQD 1736
Query: 494 EERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKRE 553
E+RR E R QL E EE Q E + R+R Q Q E+ L E
Sbjct: 1737 EKRR--LEARIAQLEEELEEE-------QGNMEAMSDRVRKATQ----QAEQLSNELATE 1783
Query: 554 EEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQE 613
+ E Q+L+R+ +E R +L E E + + LE ++ + E E++EQE
Sbjct: 1784 RSTAQKNESARQQLERQNKELRSKL--HEMEGAVKSKFKSTIAALEAKIAQLE-EQVEQE 1840
Query: 614 ERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKR--------EEEE 665
R +Q + +++++ + + + ++ER+ + +EQ E+ R+K+ EEE
Sbjct: 1841 AREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEES 1900
Query: 666 ERLE---QRLKREHEEERREQELAEEEQEQARERIK 698
+R+ ++L+RE +E E E + +++
Sbjct: 1901 QRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 109 bits (272), Expect = 3e-23
Identities = 105/487 (21%), Positives = 231/487 (47%), Gaps = 30/487 (6%)
Query: 116 EEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWR 175
E D+ E R+++ + R ++ E + EL E++ K + E D +++ +
Sbjct: 1477 ERDRAEAEAREKETKALSLARALEEALEAKEEL----ERTNKMLKAEMEDLVSSKDDVGK 1532
Query: 176 QRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQD 235
E ++ +RA E Q++ K + EE DE Q L L + K Q R+ Q
Sbjct: 1533 NVHELEK--SKRALETQMEEMKT-QLEELEDELQATEDAKLRLEVNMQALKGQFERDLQA 1589
Query: 236 RVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR------QRELQEEEEQLRKLERQELRRE 289
R Q EE++ +R+ L + E +L++E QR +++L+ + + L +L+ +
Sbjct: 1590 RDEQNEEKRRQLQRQ--LHEYETELEDERKQRALAAAAKKKLEGDLKDL-ELQADSAIKG 1646
Query: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQ 349
R+E +Q ++L+ + + +++ E+ R ++E + E++ + E L + QE+
Sbjct: 1647 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1706
Query: 350 QLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR-EQQLRREQQLRREQQLR 408
+ R+Q + +E+ L E + ++++ R E ++ + E++L EQ R
Sbjct: 1707 ERARKQADLEKEE-LAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1765
Query: 409 REQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHE 468
+ ++ +QL E R ++ + + ER+ + L+ + E +K + ++
Sbjct: 1766 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1825
Query: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 528
E + QL+ E+E RE K + +Q++++ +++ + E+ R+ + +E+ E+
Sbjct: 1826 LEAKIAQLEEQVEQEARE---KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1882
Query: 529 QQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQ 588
R++ QL+R+ EE EE +R+ RR+ + + ++ ++ + RE +
Sbjct: 1883 NARVK---QLKRQLEE------AEEESQRINANRRKLQRELDEATESNEAMGREVNALKS 1933
Query: 589 RLKREQE 595
+L+R E
Sbjct: 1934 KLRRGNE 1940
Score = 107 bits (267), Expect = 1e-22
Identities = 131/594 (22%), Positives = 267/594 (44%), Gaps = 65/594 (10%)
Query: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRK 1415
+ERD K + + Q R +L + +RQ++ + Q C + R
Sbjct: 787 EERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAM--KVIQRNCAAYLKLRNWQWWRL 844
Query: 1416 FREEEQ--QLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE- 1472
F + + Q++RQE + + +E+E Q + +ER++K E ++L Q +H + EE+ LLQE
Sbjct: 845 FTKVKPLLQVTRQEEEMQAKEDELQ-KTKERQQKAENELKELEQ-KHSQLTEEKNLLQEQ 902
Query: 1473 -REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR 1531
+ E +L+ + + + ++QE + E E R +E E + ++ Q R++ +
Sbjct: 903 LQAETELYAEAEE---MRVRLAAKKQELEEILHEMEARLEEEEDR--GQQLQAERKKMAQ 957
Query: 1532 KFLQEEQQLRRQERGQQRRQ------DRDRKFREEEQLRQEREEQQLSRQERDRKFRLEE 1585
+ L E+QL +E +Q+ Q + K E+E L + + +LS++ + + R+ +
Sbjct: 958 QMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1017
Query: 1586 QKVRRQEQERKFMEDEQQLRRQE---GQQQLRQERDRKFREDEQLLQ---EREEQQLHRQ 1639
E+E K + + E + ++R +++ K R++ + L+ E + H Q
Sbjct: 1018 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1077
Query: 1640 ERD--RKFLEEEPQLRRQEREQQLRHDR-DRKFREEEQLLQEGEEQQLRRQERDRKFREE 1696
D + E + QL ++E E Q R D + ++ L++ E + + E
Sbjct: 1078 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1137
Query: 1697 EQQLRRQERERKFLQEEQQLRRQELERKF---REEEQLRQETEQEQLRRQERYRKILEEE 1753
+ E++++ L EE + + ELE +++LR + EQE +K L+EE
Sbjct: 1138 RAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQE----VTVLKKALDEE 1193
Query: 1754 QLRPEREEQQLRRQERDRKFREEEQLRQ--------EREEQQLRSQESD----------- 1794
E + Q++R++ EQL Q ++ +Q L + +D
Sbjct: 1194 TRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQA 1253
Query: 1795 RKFREEEQLRQEREEQQLRPQQRDGKY-------RWEEEQLQLEEQEQRLRQERDRQYRA 1847
++ E ++ + E + Q+L+ + DG+ + + Q ++E L + + +
Sbjct: 1254 KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKL 1313
Query: 1848 EEQFATQEKSRREEQELWQEEEQKRR--QERERKLREEH--IRRQQKEEQRHRQ 1897
+ A+ ++ QEL QEE +++ + R+L EE ++ Q EE +Q
Sbjct: 1314 AKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1367
Score = 89.7 bits (221), Expect = 2e-17
Identities = 97/447 (21%), Positives = 211/447 (47%), Gaps = 38/447 (8%)
Query: 1507 ELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE 1566
++ QE E + E+E Q ++++Q+ E +L+ E Q+ Q + K +EQL+ E
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKA----ENELKELE--QKHSQLTEEKNLLQEQLQAE 906
Query: 1567 REEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQ-QQLRQERDRKFREDE 1625
E L + + + RL +K QE E E E +L +E + QQL+ ER + ++
Sbjct: 907 TE---LYAEAEEMRVRLAAKK---QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 960
Query: 1626 QLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR 1685
L ++ EE++ RQ+ + + E ++++ E E + D++ K +E +LL+E R
Sbjct: 961 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEE------R 1014
Query: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQ-- 1743
+ EEE++ + + L+ + + ELE + ++EE+ RQE E+ + + +
Sbjct: 1015 ISDLTTNLAEEEEKAKNLTK----LKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1070
Query: 1744 -ERYRKILEEEQLRPEREEQQLRRQERDRK---FREEEQLRQEREE-QQLRSQESDRKFR 1798
+ + + + Q + + QL ++E + + R ++++ Q+ +++R E
Sbjct: 1071 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDL 1130
Query: 1799 EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSR 1858
+E+ + + Q+RD E + +LE+ +++ + + E++ +K+
Sbjct: 1131 QEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKAL 1190
Query: 1859 REEQELWQEEEQKRRQERERKLRE-----EHIRRQQKEEQRHRQVGEIKSQEGKGHGRLL 1913
EE + + Q+ RQ+ + + E E +R + +++Q E ++ + G R+L
Sbjct: 1191 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1250
Query: 1914 EPGTHQFASVPVRSSPLYEYIQEQRSQ 1940
+ V + L +QE +S+
Sbjct: 1251 GQAKQE---VEHKKKKLEAQVQELQSK 1274
Score = 65.1 bits (157), Expect = 6e-10
Identities = 64/274 (23%), Positives = 126/274 (45%), Gaps = 31/274 (11%)
Query: 1643 RKFLEEEP--QLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQL 1700
R F + +P Q+ RQE E Q + D +K +E +Q + E + +++ + EE+ L
Sbjct: 843 RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQ---KAENELKELEQKHSQLTEEKNLL 899
Query: 1701 RRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPERE 1760
+ Q + L E + R L K +E E++ E E ++R +QL+ ER+
Sbjct: 900 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDR------GQQLQAERK 953
Query: 1761 EQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGK 1820
+ + + + + EEE RQ+ + +++ ++ +K E+E L + + +L +++ +
Sbjct: 954 KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL-EDEILVMDDQNNKLSKERKLLE 1012
Query: 1821 YRWEEEQLQLEEQEQRLRQERDRQYRAEEQFAT-------QEKSRREEQELWQEEEQKRR 1873
R + L E+E++ + + + E + +EKSR+E ++L KR+
Sbjct: 1013 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKL------KRK 1066
Query: 1874 QERERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
E + E I Q Q+ E+K Q K
Sbjct: 1067 LEGDASDFHEQIADLQ------AQIAELKMQLAK 1094
Score = 34.3 bits (77), Expect = 1.2
Identities = 22/107 (20%), Positives = 48/107 (44%), Gaps = 19/107 (17%)
Query: 1821 YRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKL 1880
++W +++ Q RQE + Q + +E T+E+ ++ E EL + E++ + E+ L
Sbjct: 839 WQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNL 898
Query: 1881 REEHI-------------------RRQQKEEQRHRQVGEIKSQEGKG 1908
+E + ++Q+ EE H ++ +E +G
Sbjct: 899 LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 945
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 215 bits (547), Expect = 4e-55
Identities = 258/1127 (22%), Positives = 508/1127 (45%), Gaps = 118/1127 (10%)
Query: 286 LRRERQEEEQQ--QQRLRREQQLRRKQEEERREQQEERREQQERRE--QQEERREQQLRR 341
L+ RQEEE Q + L++ ++ ++K E E +E +++ + E + Q++ + E +L
Sbjct: 852 LQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYA 911
Query: 342 EQEERREQQLRREQE-EERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQ 400
E EE R + ++QE EE + R +EEE R QQL+ E++ +Q L E+QL E+
Sbjct: 912 EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEA 971
Query: 401 LRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR----EQRLKREQEERRD 456
R++ QL + + ++L E + +Q + +++ E R L E+E+ ++
Sbjct: 972 ARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN 1031
Query: 457 W--LKREEETERHEQE-RRKQQLKRDQEEERRERWLKLEEEERRE-------QQERREQQ 506
LK + E+ E E R K++ K QE E+ +R L+ + + E Q + Q
Sbjct: 1032 LTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQ 1091
Query: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL-LKREEEKRLEQERRE- 564
L +++EE + + +E + L+ ++L + +E L +R + E+++R+
Sbjct: 1092 LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDL 1151
Query: 565 ----QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620
+ LK E E+ D ++E R KREQE + ++ EE R + + +E R
Sbjct: 1152 GEELEALKTELEDTLDSTATQQE----LRAKREQEVTVLKKALDEET-RSHEAQVQEMRQ 1206
Query: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQ-RLKREHEEE 679
K + EE +QL EQ +R + L + +Q ++ E L Q + + EH+++
Sbjct: 1207 KHAQAVEELTEQL----EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKK 1262
Query: 680 RREQELAE-----EEQEQARERIKSRIPKWQWQLES------EADARQSKVYS-----RP 723
+ E ++ E + E+AR + ++ K Q ++ES EA+ + K+
Sbjct: 1263 KLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1322
Query: 724 RKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQR 783
+ Q+ Q QE+ ++ ++L+ EEER Q Q +E + +A++ ER
Sbjct: 1323 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDE-------EMEAKQNLERHIST 1375
Query: 784 LSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRR 843
L+ QL +++ ++ E E+ ++R Q+ Q+ E+ +
Sbjct: 1376 LNI----------QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1425
Query: 844 ERAQ-QLQEEEDGLQEDQERRR---SQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQL 899
E+ + +LQ+E D L D + +R S +++ +K+ L EE+ + E+
Sbjct: 1426 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKN------ISSKYADERD 1479
Query: 900 RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959
R E + ++E + L + + +E R + L+ E E L+ + + + +
Sbjct: 1480 RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK 1539
Query: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR------EEREKRRR 1013
++ + Q +E + EE E + + K R E +Q + Q R E+ E++RR
Sbjct: 1540 SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1599
Query: 1014 QEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRR 1073
Q + + + EL+ E +Q K++L E ++ E Q + + G E ++
Sbjct: 1600 QLQRQLHEYETELEDERKQRALAAAAKKKL---EGDLKDLE--LQADSAIKGREEAIKQL 1654
Query: 1074 QELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRR 1133
++L+ Q K+ + + E+ + R+E ++ ++ E +L Q +E L ER R++
Sbjct: 1655 RKLQAQ-MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER-ARKQ 1712
Query: 1134 QELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQ 1193
+LE++ EE + ++ EKRR + Q EE E +Q + + + K Q
Sbjct: 1713 ADLEKEELAEELASSLSGRNALQD-EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1771
Query: 1194 ERERQYRE---EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQF 1250
+ E+ E E ++ R + E Q +L+ + E E AV+ +
Sbjct: 1772 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH-EMEGAVKSKFKSTIAALEAKI 1830
Query: 1251 RQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE-------EEQLEREE 1303
QLE+ EQ+ R+++ + +Q+D+ E E ++ +
Sbjct: 1831 AQLEEQV---------------EQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY 1875
Query: 1304 QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE 1350
+++A++ + + ++ K+ L E EE +R RK + E E E
Sbjct: 1876 KEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNE 1922
Score = 213 bits (543), Expect = 1e-54
Identities = 273/1151 (23%), Positives = 522/1151 (45%), Gaps = 146/1151 (12%)
Query: 518 RLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQ 577
++ RQEEE Q E Q +E++++ E LK E+K Q E+ L +EQ + +
Sbjct: 853 QVTRQEEE---MQAKEDELQKTKERQQKAENELKELEQKH-SQLTEEKNLLQEQLQAETE 908
Query: 578 LLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSE 637
L EE R + ++QE LE+ L E RLE+EE R Q+L+ E ++ QQ+L E
Sbjct: 909 LYAEAEEMRVRLAAKKQE--LEEILHEMEA-RLEEEEDRGQQLQAER--KKMAQQMLDLE 963
Query: 638 EQEERRQQQLRREQQER--REQRLKREEEEERL--EQRLKREHEEERREQELAEEEQEQA 693
EQ E + ++ Q E+ E ++K+ E+E + +Q K E + E+ +++ A
Sbjct: 964 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1023
Query: 694 RERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEER 753
E K+ K +L+++ ++ S++ R +K+E + RQE E+ +R+ E + E+
Sbjct: 1024 EEEEKA---KNLTKLKNKHESMISELEVRLKKEE--KSRQELEKLKRKLEGDASDFHEQI 1078
Query: 754 AHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE 813
A Q Q E + + EE+ + RL + +++R + E
Sbjct: 1079 ADLQAQIAELKMQLA---KKEEELQAALARLDDEIAQKNNALKKIR-----ELEGHISDL 1130
Query: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQK 873
+E+ + R R + EK+ + L EE + + E L++ D QE R +EQ
Sbjct: 1131 QEDLDSERAARNKAEKQKRDLGEELEALKTE----LEDTLDSTATQQELRAKREQEVTVL 1186
Query: 874 WRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREE 933
+ EE R +QE +K Q ++E E+L++ +R K + +
Sbjct: 1187 KKALDEETRSHEAQ-------VQEMRQKHAQAVEELTEQLEQFKRAKANLD------KNK 1233
Query: 934 EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE 993
+ L++E L E R + ++ +K + Q +E Q + E+ R + +K ++ +
Sbjct: 1234 QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1293
Query: 994 EELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREE 1053
E++ L E E + + + +LQ +E L E R+K + + RQ EE
Sbjct: 1294 NEVESVTGML--NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEE 1351
Query: 1054 EELQQEEEQLLGEERETRRRQE---------LERQYRKEEELQQEEEQLLREEPEKRRRQ 1104
Q++ L EE E ++ E L +K ++ E L EE +KR ++
Sbjct: 1352 RNSLQDQ---LDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEAL--EEGKKRFQK 1406
Query: 1105 ERERQCREEEE--------------LQQEEEQLLRE-EREKRRRQELERQYREEEEVQQE 1149
E E ++ EE LQQE + L+ + + +++ LE++ R+ +++ E
Sbjct: 1407 EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1466
Query: 1150 EEQLLREEPEKRRRQELERQYRE----------EEELQQEEE-----QLLREEQEKRRQE 1194
E+ + + ++R R E E + +E EE L+ +EE ++L+ E E
Sbjct: 1467 EKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSS 1526
Query: 1195 RERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKE-NAVRDNKVYCKGRENEQFRQL 1253
++ + EL++ KR + E+ ++ L+ E E E A D K+ + Q
Sbjct: 1527 KDDVGKNVHELEKSKRALETQMEEMKTQLE---ELEDELQATEDAKLRLEVNMQALKGQF 1583
Query: 1254 E-DSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLERE---------- 1302
E D Q RD Q+++ + L + E + E E R +QR +++LE +
Sbjct: 1584 ERDLQARDEQNEEKRRQLQRQLHEYETELEDER-KQRALAAAAKKKLEGDLKDLELQADS 1642
Query: 1303 ---EQKEAKRRDRKSQEEKQLLREEREEKRRRQ--------ETDRKFREEEQLLQEREEQ 1351
++EA ++ RK Q + + + E E+ R + E ++K + E L + +E
Sbjct: 1643 AIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1702
Query: 1352 PLRRQERDRKFRE-------EELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQER 1404
L ER RK + EEL GR L++E+R E + + E++L ++
Sbjct: 1703 -LAAAERARKQADLEKEELAEELASSLSGRNALQDEKR----RLEARIAQLEEELEEEQG 1757
Query: 1405 EQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFR 1464
+ DR RK ++ +QLS + + ++ + RQ+ ER + ++LR + H
Sbjct: 1758 NMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER----QNKELRSKLH---- 1809
Query: 1465 EEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFL----EE 1520
E E ++ + + + E K + E+Q+ ++ R+++ + L+ ++ + K + E+
Sbjct: 1810 EMEGAVKSKFKSTIAALEA--KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1867
Query: 1521 EQQLHRQQRQR--KFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERD 1578
E+++ Q +++ K +QL+RQ ++ ++ R +L++E +E S +
Sbjct: 1868 ERKMAEQYKEQAEKGNARVKQLKRQL--EEAEEESQRINANRRKLQRELDEATESNEAMG 1925
Query: 1579 RKFRLEEQKVR 1589
R+ + K+R
Sbjct: 1926 REVNALKSKLR 1936
Score = 201 bits (510), Expect = 8e-51
Identities = 260/1122 (23%), Positives = 515/1122 (45%), Gaps = 125/1122 (11%)
Query: 91 QATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAE 150
Q T +EE +A KE LQ + +E Q++ E ++LE++ Q +K QE+ AE
Sbjct: 853 QVTRQEEEMQA----KEDELQ--KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 906
Query: 151 GEEQSEKQE-RLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHET----EEFP 205
E +E +E R+ +++ EE+ + + E EE R ++ Q + K + EE
Sbjct: 907 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL 966
Query: 206 DEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265
+EE+ R++L K E + ++ E + V ++ K L KE + L+E
Sbjct: 967 EEEEAARQKL--QLEKVTAEAKIKKLEDEILVMDDQNNK--------LSKERKLLEERIS 1016
Query: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ---EERR 322
L EEEE+ + L + + + E E + RL++E++ R++ E+ +R+ + +
Sbjct: 1017 DLTTNLAEEEEKAKNLTKLKNKHESMISE-LEVRLKKEEKSRQELEKLKRKLEGDASDFH 1075
Query: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQ 382
EQ + Q + QL +++EE + R + E ++ L++ +E E L+ +
Sbjct: 1076 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLD 1135
Query: 383 LRREQQLRREQQLRREQQLRREQQLRREQQL-----RREQQLRREQQ---LRREQEEERH 434
R + + E+Q R + + E L ++E + +REQ+ L++ +EE
Sbjct: 1136 SERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEE-- 1193
Query: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQ-ERRKQQLKRDQEEERRER------ 487
+ HE + +E R K Q EE TE+ EQ +R K L ++++ +E
Sbjct: 1194 TRSHEAQVQEMRQKHAQAV-------EELTEQLEQFKRAKANLDKNKQTLEKENADLAGE 1246
Query: 488 -----WLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
K E E ++++ E + Q+L+ + + R + ++ +LQ + S + E
Sbjct: 1247 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEA 1306
Query: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRD---QLLKREEERR--QQRLKREQE-- 595
E + +L K + + ++ L+ E ++ + +L + EEER Q +L E E
Sbjct: 1307 EGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAK 1366
Query: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ--EERRQQQLRREQQE 653
+ LE+ + ++ + +++ + E EE +++ K E ++ ++ ++ E
Sbjct: 1367 QNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLE 1426
Query: 654 RREQRLKREEEE-----ERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQL 708
+ + RL++E ++ + Q + +++R+ +L EE + I S+ + +
Sbjct: 1427 KTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE-----KNISSKYADERDRA 1481
Query: 709 ESEADARQSKVYSRPRK-QEGQRRRQEQEEKRRRRESELQ------------WQEEERAH 755
E+EA +++K S R +E ++E E + ++E++ E E++
Sbjct: 1482 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1541
Query: 756 R--QQQEEEQRRDFTWQWQAEEKSERGRQRLSAR-PPLREQRERQLRA-----EERQQRE 807
R + Q EE + + +E + RL L+ Q ER L+A EE++++
Sbjct: 1542 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1601
Query: 808 QRFLPE-EEEKEQRRRQR-------REREKELQFLE--EEEQLQRRERA-QQLQEEEDGL 856
QR L E E E E R+QR ++ E +L+ LE + ++ RE A +QL++ + +
Sbjct: 1602 QRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQM 1661
Query: 857 QEDQERRRSQEQRRDQKWRWQLEEERKRRR-----HTLYAKPALQEQLRKEQQLLQEE-E 910
++ Q RD+ + E E+K + L A E+ RK+ L +EE
Sbjct: 1662 KDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA 1721
Query: 911 EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKE 970
EEL + Q+++R R E ++ Q EE+L E+ +R R K Q+
Sbjct: 1722 EELASSLSGRNALQDEKR--RLEARIAQLEEELEEEQGNMEAMSDRVR------KATQQA 1773
Query: 971 EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKD-ELQQE 1029
EQL E +R ++ + R++ E Q +E + E E + +++ + ++ Q
Sbjct: 1774 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1833
Query: 1030 EEQLLREEREK----RRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
EEQ+ +E REK + L++++++ + E LQ E+E+ + E+ + + + R + + +
Sbjct: 1834 EEQVEQEAREKQAATKSLKQKDKKLK-EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQ 1892
Query: 1086 LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127
L++ EE+ R +R+ Q + E E E L+ +
Sbjct: 1893 LEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1934
Score = 200 bits (508), Expect = 1e-50
Identities = 256/1143 (22%), Positives = 523/1143 (45%), Gaps = 124/1143 (10%)
Query: 833 FLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAK 892
F + + LQ + +++Q +ED LQ+ +ER++ E +L+E ++ K
Sbjct: 845 FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAEN--------ELKELEQKHSQLTEEK 896
Query: 893 PALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRR 952
LQEQL+ E +L E EE R +K+ E E++ E E L EE ++ +
Sbjct: 897 NLLQEQLQAETELYAEAEEMRVRLAAKKQ----------ELEEILHEMEARLEEEEDRGQ 946
Query: 953 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1012
+ + ER+ + L +E+ L EE R++ + EK E + + E+E L+ +++ +
Sbjct: 947 QLQAERKKMAQQMLDLEEQ--LEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKL 1004
Query: 1013 RQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRR 1072
+E + + +L L EE EK + + + + E + + E +L EE+
Sbjct: 1005 SKERKLLEERISDLTTN----LAEEEEKAKNLTKLKN-KHESMISELEVRLKKEEKS--- 1056
Query: 1073 RQELERQYRK-EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE----EEQLLREE 1127
RQELE+ RK E + EQ+ + + + + + + ++EEELQ ++++ ++
Sbjct: 1057 RQELEKLKRKLEGDASDFHEQIA--DLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1114
Query: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRR---QELERQYREEEEL-----QQE 1179
++ +ELE + +E + E+ R + EK++R +ELE E E+ Q+
Sbjct: 1115 NALKKIRELEGHISDLQE-DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQ 1173
Query: 1180 EEQLLREEQ----EKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV 1235
E + RE++ +K E R + + + RQK Q + ++ + Q++ K N
Sbjct: 1174 ELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE---QFKRAKANLD 1230
Query: 1236 RDNKVYCKGREN--EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHF 1293
++ + K + + R L ++ ++ L+ + E Q + + ER R + D+
Sbjct: 1231 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1290
Query: 1294 PEEEQLER-------------EEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE 1340
+ ++E + K+ + Q+ ++LL+EE +K R+ E
Sbjct: 1291 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1350
Query: 1341 EEQLLQER-EEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR-QERERKFLKEEQQ 1398
E LQ++ +E+ +Q +R ++ + +K + + +E +++F KE +
Sbjct: 1351 ERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN 1410
Query: 1399 LRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQE 1458
L Q E+ D K + + +L ++ D + Q+ E+K + +Q L +E
Sbjct: 1411 LTQQYEEKAAAYD---KLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1467
Query: 1459 RH--RKFREE----EQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQE 1512
++ K+ +E E +E+E + L + LE +++L R + K ++L S +
Sbjct: 1468 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSK 1527
Query: 1513 PERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQL 1572
+ + +H ++ ++ L+ + + + + Q + + + E+ +LR E Q L
Sbjct: 1528 DD-----VGKNVHELEKSKRALETQME---EMKTQLEELEDELQATEDAKLRLEVNMQAL 1579
Query: 1573 SRQ-ERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQER 1631
Q ERD + R E+ + +R++ +R+ E E +L + Q+ L +K D + L+ +
Sbjct: 1580 KGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ 1639
Query: 1632 EEQQLH-RQERDRKFLEEEPQLRRQERE-QQLRHDRDRKF---REEEQLLQEGE------ 1680
+ + R+E ++ + + Q++ +RE + R RD F +E E+ + E
Sbjct: 1640 ADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQL 1699
Query: 1681 EQQLRRQERDRKFREEEQQLRRQERE-----RKFLQEEQ---QLRRQELERKFREEE--- 1729
++ L ER RK + E++ +E R LQ+E+ + R +LE + EE+
Sbjct: 1700 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM 1759
Query: 1730 -----QLRQETEQ-EQLRRQERYRKILEEEQLRPEREEQQLRRQERD--RKFREEEQLRQ 1781
++R+ T+Q EQL + + ++ E QQL RQ ++ K E E +
Sbjct: 1760 EAMSDRVRKATQQAEQLSNELATERSTAQKN---ESARQQLERQNKELRSKLHEMEGAVK 1816
Query: 1782 EREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQER 1841
+ + + + E+ EE+ ++ RE+Q + + +E LQ+E++ + Q +
Sbjct: 1817 SKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYK 1876
Query: 1842 DRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEI 1901
+ +AE+ A ++ +R+ +E EEE +R RKL+ E + E R+V +
Sbjct: 1877 E---QAEKGNARVKQLKRQLEE--AEEESQRINANRRKLQRELDEATESNEAMGREVNAL 1931
Query: 1902 KSQ 1904
KS+
Sbjct: 1932 KSK 1934
Score = 200 bits (508), Expect = 1e-50
Identities = 262/1108 (23%), Positives = 513/1108 (46%), Gaps = 155/1108 (13%)
Query: 213 RELLELRR-----KGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR 267
+ LL++ R + +E++ Q+ +ERQ + E E KE ++ + L EE+ L +E+ Q
Sbjct: 849 KPLLQVTRQEEEMQAKEDELQKTKERQQKA--ENELKELEQKHSQL-TEEKNLLQEQLQA 905
Query: 268 QRELQEEEEQLR------KLERQELRRER----QEEEQQQQRLRREQQLRRKQEEERREQ 317
+ EL E E++R K E +E+ E +EEE + Q+L+ E++ +Q + EQ
Sbjct: 906 ETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ 965
Query: 318 QEERREQQERREQQEERREQQLRREQEE-----RREQQLRREQE--EERREQQLRREQEE 370
EE +++ + ++ E ++++ ++E + +L +E++ EER EE
Sbjct: 966 LEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1025
Query: 371 ERREQQLRREQQLRREQQLRREQQLRREQQLRRE-QQLRREQQ---LRREQQLRREQQLR 426
E + + L + + E +L++E++ R+E ++L+R+ + +Q+ Q
Sbjct: 1026 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1085
Query: 427 REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRE 486
E + + +++ E + RL E ++ + LK+ E E H + L+ D + ER
Sbjct: 1086 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISD-----LQEDLDSERAA 1140
Query: 487 RWLKLEEEERREQQERREQQLRREQEE-------RREQRLKRQEEEERLQQRLRSE---- 535
R E+++R+ E E L+ E E+ ++E R KR++E L++ L E
Sbjct: 1141 R--NKAEKQKRDLGEELE-ALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH 1197
Query: 536 ----QQLRREQEERREQLLKREEE---KRLEQERREQRLKREQEERRDQL-----LKREE 583
Q++R++ + E+L ++ E+ + ++ +Q L++E + +L K+E
Sbjct: 1198 EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEV 1257
Query: 584 ERRQQRLKREQEERLE-----QRLKRE---EVERLEQE---------ERREQRLKREEPE 626
E ++++L+ + +E +R + E +V +L+ E E + +K +
Sbjct: 1258 EHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1317
Query: 627 EERRQQLLKSEE--QEERRQQ-----QLRREQQERREQRLKREEEEERLEQRLKRE---- 675
QL ++E QEE RQ+ +LR+ ++ER + + +EE E +Q L+R
Sbjct: 1318 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME-AKQNLERHISTL 1376
Query: 676 ----HEEERREQELAE--EEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ--- 726
+ +++ Q+ A E E+ ++R + I Q E +A A ++ R Q
Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL 1436
Query: 727 -------EGQRRRQEQEEKRRRRESELQWQEE----------ERAHRQQQEEEQR----- 764
+ QR+ EK++R+ +L +E+ +RA + +E+E +
Sbjct: 1437 DDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLA 1496
Query: 765 RDFTWQWQAEEKSERGRQRLSAR-PPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQ 823
R +A+E+ ER + L A L ++ + ++ +R L E + E+ + Q
Sbjct: 1497 RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL--ETQMEEMKTQ 1554
Query: 824 RREREKELQFLEEEE-QLQRRERAQQLQEEED--GLQEDQERRRSQEQRRDQKWRWQLEE 880
E E ELQ E+ + +L+ +A + Q E D E E +R Q QR+ ++ +LE+
Sbjct: 1555 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELED 1614
Query: 881 ERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEE 940
ERK+R AK L+ L+ + LQ + REE K+ R+ Q + ++ Q + E+
Sbjct: 1615 ERKQRALAAAAKKKLEGDLKDLE--LQADSAIKGREEAIKQLRKLQAQM--KDFQRELED 1670
Query: 941 EQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEE 1000
+ R+E ++ ++ + L Q +E L E + R++ E+EEL +E
Sbjct: 1671 ARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE------RARKQADLEKEELAEEL 1724
Query: 1001 EQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEE 1060
L R + + R + + Q EE+L E+ + +R R+ ++ E E
Sbjct: 1725 ASSL-----SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1779
Query: 1061 EQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEE 1120
L ER T ++ E RQ + E +E L E + + + E ++ Q E
Sbjct: 1780 ---LATERSTAQKNESARQ--QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLE 1834
Query: 1121 EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE 1180
EQ+ +E REK+ + +Q + ++ +E LL+ E E++ + QY+E+ E
Sbjct: 1835 EQVEQEAREKQAATKSLKQ-----KDKKLKEILLQVEDERK----MAEQYKEQAEKGNAR 1885
Query: 1181 EQLLREEQEKRRQERERQYREEEELQRQ 1208
+ L+ + E+ +E +R +LQR+
Sbjct: 1886 VKQLKRQLEEAEEESQRINANRRKLQRE 1913
Score = 188 bits (478), Expect = 4e-47
Identities = 250/1153 (21%), Positives = 513/1153 (44%), Gaps = 131/1153 (11%)
Query: 680 RREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQE--QEE 737
+R+Q+L + Q ++ WQW + + R++E + +++ Q+
Sbjct: 815 KRQQQLTAMKVIQRNCAAYLKLRNWQWW---RLFTKVKPLLQVTRQEEEMQAKEDELQKT 871
Query: 738 KRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAE--EKSERGRQRLSARPPLREQ-- 793
K R++++E + +E E+ H Q EE+ Q + E ++E R RL+A+ E+
Sbjct: 872 KERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEIL 931
Query: 794 RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
E + R EE + R Q+ E ++ Q+ E+ +E + ++ QL++ ++++ E
Sbjct: 932 HEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLE 991
Query: 854 DGL--QEDQERRRSQEQR----RDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQ 907
D + +DQ + S+E++ R L EE ++ ++ K + + + + L+
Sbjct: 992 DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK 1051
Query: 908 EEEEELQREEREKRRRQEQERQYREE-----EQLQQEEEQLLREERE-----KRRRQERE 957
+EE+ Q E+ KR+ + + E+ Q+ + + QL ++E E R E
Sbjct: 1052 KEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIA 1111
Query: 958 RQYRKDKKLQQKEEQLLG-EEPEKRRRQEREKKYREEEELQQEEEQLLRE---------- 1006
++ KK+++ E + +E R R K +++ +L +E E L E
Sbjct: 1112 QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTAT 1171
Query: 1007 EREKRRRQEWERQYRKK--DELQQEEEQLLREEREKR-----RLQERERQYRE------- 1052
++E R ++E E KK DE + E ++E R+K L E+ Q++
Sbjct: 1172 QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK 1231
Query: 1053 -EEELQQEEEQLLGEERET-RRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQC 1110
++ L++E L GE R + +QE+E + +K+ E Q +E Q + E+ R + ++
Sbjct: 1232 NKQTLEKENADLAGELRVLGQAKQEVEHK-KKKLEAQVQELQSKCSDGERARAELNDKVH 1290
Query: 1111 REEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQY 1170
+ + E++ L E + + L + Q+ ++LL+EE R++ + +
Sbjct: 1291 KLQNEVESVTGMLNEAEGKAIK---LAKDVASLSSQLQDTQELLQEET--RQKLNVSTKL 1345
Query: 1171 RE-EEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDE-DQRSDLKWQWE 1228
R+ EEE ++QL E + K+ ER + +K+ Q + + + K +++
Sbjct: 1346 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1405
Query: 1229 PEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE--RDREQERRRW 1286
E EN + + + + +LE ++ R +Q DL L Q++ + E+++R++
Sbjct: 1406 KEIENLTQQYE-----EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKF 1460
Query: 1287 QQ---RDRHFPEEEQLEREE-QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREE- 1341
Q +++ + ER+ + EA+ ++ K+ + L E E K + T++ + E
Sbjct: 1461 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1520
Query: 1342 EQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRC 1401
E L+ +++ E ++ R E + +E + E E L+ E + +LR
Sbjct: 1521 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE--------DAKLRL 1572
Query: 1402 QEREQQLRQ--DRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQER 1459
+ Q L+ +RD + R+E+ + R++ R+ E E ++ ER+++ L + + E
Sbjct: 1573 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELE-DERKQRALAAAAKKKLEG 1631
Query: 1460 HRKFRE--EEQLLQEREE--QQLHRQERDRKFLEEEQQLRRQERDRKF---REQELRSQE 1512
K E + ++ REE +QL + + K + E + R RD F +E E +++
Sbjct: 1632 DLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1691
Query: 1513 PERKFLEEEQQLHRQQRQRKFLQEEQQLRRQE-----RGQQRRQDRDRKFRE-----EEQ 1562
E ++ ++ L +R RK E++ +E G+ QD R+ EE+
Sbjct: 1692 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE 1751
Query: 1563 LRQER---------------EEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQ 1607
L +E+ + +QLS + + ++ + RQ+ ER+ E +L
Sbjct: 1752 LEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEM 1811
Query: 1608 EGQQQLRQERDRKFRE------DEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQL 1661
EG + + + E +EQ+ QE E+Q + +K + + L + E E+++
Sbjct: 1812 EGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKM 1871
Query: 1662 RHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQEL 1721
EQ ++ E+ R ++ R+ E E++ +R R+ LQ E +
Sbjct: 1872 ----------AEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESN 1921
Query: 1722 ERKFREEEQLRQE 1734
E RE L+ +
Sbjct: 1922 EAMGREVNALKSK 1934
Score = 107 bits (267), Expect = 1e-22
Identities = 131/594 (22%), Positives = 267/594 (44%), Gaps = 65/594 (10%)
Query: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRK 1415
+ERD K + + Q R +L + +RQ++ + Q C + R
Sbjct: 787 EERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAM--KVIQRNCAAYLKLRNWQWWRL 844
Query: 1416 FREEEQ--QLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE- 1472
F + + Q++RQE + + +E+E Q + +ER++K E ++L Q +H + EE+ LLQE
Sbjct: 845 FTKVKPLLQVTRQEEEMQAKEDELQ-KTKERQQKAENELKELEQ-KHSQLTEEKNLLQEQ 902
Query: 1473 -REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR 1531
+ E +L+ + + + ++QE + E E R +E E + ++ Q R++ +
Sbjct: 903 LQAETELYAEAEE---MRVRLAAKKQELEEILHEMEARLEEEEDR--GQQLQAERKKMAQ 957
Query: 1532 KFLQEEQQLRRQERGQQRRQ------DRDRKFREEEQLRQEREEQQLSRQERDRKFRLEE 1585
+ L E+QL +E +Q+ Q + K E+E L + + +LS++ + + R+ +
Sbjct: 958 QMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1017
Query: 1586 QKVRRQEQERKFMEDEQQLRRQE---GQQQLRQERDRKFREDEQLLQ---EREEQQLHRQ 1639
E+E K + + E + ++R +++ K R++ + L+ E + H Q
Sbjct: 1018 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1077
Query: 1640 ERD--RKFLEEEPQLRRQEREQQLRHDR-DRKFREEEQLLQEGEEQQLRRQERDRKFREE 1696
D + E + QL ++E E Q R D + ++ L++ E + + E
Sbjct: 1078 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1137
Query: 1697 EQQLRRQERERKFLQEEQQLRRQELERKF---REEEQLRQETEQEQLRRQERYRKILEEE 1753
+ E++++ L EE + + ELE +++LR + EQE +K L+EE
Sbjct: 1138 RAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQE----VTVLKKALDEE 1193
Query: 1754 QLRPEREEQQLRRQERDRKFREEEQLRQ--------EREEQQLRSQESD----------- 1794
E + Q++R++ EQL Q ++ +Q L + +D
Sbjct: 1194 TRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQA 1253
Query: 1795 RKFREEEQLRQEREEQQLRPQQRDGKY-------RWEEEQLQLEEQEQRLRQERDRQYRA 1847
++ E ++ + E + Q+L+ + DG+ + + Q ++E L + + +
Sbjct: 1254 KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKL 1313
Query: 1848 EEQFATQEKSRREEQELWQEEEQKRR--QERERKLREEH--IRRQQKEEQRHRQ 1897
+ A+ ++ QEL QEE +++ + R+L EE ++ Q EE +Q
Sbjct: 1314 AKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1367
Score = 106 bits (265), Expect = 2e-22
Identities = 104/492 (21%), Positives = 231/492 (46%), Gaps = 30/492 (6%)
Query: 116 EEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWR 175
E D+ E R+++ + R ++ E + EL E++ K + E D +++ +
Sbjct: 1477 ERDRAEAEAREKETKALSLARALEEALEAKEEL----ERTNKMLKAEMEDLVSSKDDVGK 1532
Query: 176 QRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQD 235
E ++ +RA E Q++ K + EE DE Q L L + K Q R+ Q
Sbjct: 1533 NVHELEK--SKRALETQMEEMKT-QLEELEDELQATEDAKLRLEVNMQALKGQFERDLQA 1589
Query: 236 RVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR------QRELQEEEEQLRKLERQELRRE 289
R Q EE++ +R+ L + E +L++E QR +++L+ + + L +L+ +
Sbjct: 1590 RDEQNEEKRRQLQRQ--LHEYETELEDERKQRALAAAAKKKLEGDLKDL-ELQADSAIKG 1646
Query: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQ 349
R+E +Q ++L+ + + +++ E+ R ++E + E++ + E L + QE+
Sbjct: 1647 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1706
Query: 350 QLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR-EQQLRREQQLRREQQLR 408
+ R+Q + +E+ L E + ++++ R E ++ + E++L EQ R
Sbjct: 1707 ERARKQADLEKEE-LAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1765
Query: 409 REQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHE 468
+ ++ +QL E R ++ + + ER+ + L+ + E +K + ++
Sbjct: 1766 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1825
Query: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 528
E + QL+ E+E RE K + +Q++++ +++ + E+ R+ + +E+ E+
Sbjct: 1826 LEAKIAQLEEQVEQEARE---KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1882
Query: 529 QQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQ 588
R++ QL+R+ EE EE +R+ RR+ + + ++ ++ + RE +
Sbjct: 1883 NARVK---QLKRQLEE------AEEESQRINANRRKLQRELDEATESNEAMGREVNALKS 1933
Query: 589 RLKREQEERLEQ 600
+L+ + Q
Sbjct: 1934 KLRGPPPQETSQ 1945
Score = 89.7 bits (221), Expect = 2e-17
Identities = 97/447 (21%), Positives = 211/447 (47%), Gaps = 38/447 (8%)
Query: 1507 ELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE 1566
++ QE E + E+E Q ++++Q+ E +L+ E Q+ Q + K +EQL+ E
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKA----ENELKELE--QKHSQLTEEKNLLQEQLQAE 906
Query: 1567 REEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQ-QQLRQERDRKFREDE 1625
E L + + + RL +K QE E E E +L +E + QQL+ ER + ++
Sbjct: 907 TE---LYAEAEEMRVRLAAKK---QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 960
Query: 1626 QLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR 1685
L ++ EE++ RQ+ + + E ++++ E E + D++ K +E +LL+E R
Sbjct: 961 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEE------R 1014
Query: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQ-- 1743
+ EEE++ + + L+ + + ELE + ++EE+ RQE E+ + + +
Sbjct: 1015 ISDLTTNLAEEEEKAKNLTK----LKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1070
Query: 1744 -ERYRKILEEEQLRPEREEQQLRRQERDRK---FREEEQLRQEREE-QQLRSQESDRKFR 1798
+ + + + Q + + QL ++E + + R ++++ Q+ +++R E
Sbjct: 1071 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDL 1130
Query: 1799 EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSR 1858
+E+ + + Q+RD E + +LE+ +++ + + E++ +K+
Sbjct: 1131 QEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKAL 1190
Query: 1859 REEQELWQEEEQKRRQERERKLRE-----EHIRRQQKEEQRHRQVGEIKSQEGKGHGRLL 1913
EE + + Q+ RQ+ + + E E +R + +++Q E ++ + G R+L
Sbjct: 1191 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1250
Query: 1914 EPGTHQFASVPVRSSPLYEYIQEQRSQ 1940
+ V + L +QE +S+
Sbjct: 1251 GQAKQE---VEHKKKKLEAQVQELQSK 1274
Score = 65.1 bits (157), Expect = 6e-10
Identities = 64/274 (23%), Positives = 126/274 (45%), Gaps = 31/274 (11%)
Query: 1643 RKFLEEEP--QLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQL 1700
R F + +P Q+ RQE E Q + D +K +E +Q + E + +++ + EE+ L
Sbjct: 843 RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQ---KAENELKELEQKHSQLTEEKNLL 899
Query: 1701 RRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPERE 1760
+ Q + L E + R L K +E E++ E E ++R +QL+ ER+
Sbjct: 900 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDR------GQQLQAERK 953
Query: 1761 EQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGK 1820
+ + + + + EEE RQ+ + +++ ++ +K E+E L + + +L +++ +
Sbjct: 954 KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL-EDEILVMDDQNNKLSKERKLLE 1012
Query: 1821 YRWEEEQLQLEEQEQRLRQERDRQYRAEEQFAT-------QEKSRREEQELWQEEEQKRR 1873
R + L E+E++ + + + E + +EKSR+E ++L KR+
Sbjct: 1013 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKL------KRK 1066
Query: 1874 QERERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
E + E I Q Q+ E+K Q K
Sbjct: 1067 LEGDASDFHEQIADLQ------AQIAELKMQLAK 1094
Score = 34.3 bits (77), Expect = 1.2
Identities = 22/107 (20%), Positives = 48/107 (44%), Gaps = 19/107 (17%)
Query: 1821 YRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKL 1880
++W +++ Q RQE + Q + +E T+E+ ++ E EL + E++ + E+ L
Sbjct: 839 WQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNL 898
Query: 1881 REEHI-------------------RRQQKEEQRHRQVGEIKSQEGKG 1908
+E + ++Q+ EE H ++ +E +G
Sbjct: 899 LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 945
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 215 bits (547), Expect = 4e-55
Identities = 258/1127 (22%), Positives = 508/1127 (45%), Gaps = 118/1127 (10%)
Query: 286 LRRERQEEEQQ--QQRLRREQQLRRKQEEERREQQEERREQQERRE--QQEERREQQLRR 341
L+ RQEEE Q + L++ ++ ++K E E +E +++ + E + Q++ + E +L
Sbjct: 845 LQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYA 904
Query: 342 EQEERREQQLRREQE-EERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQ 400
E EE R + ++QE EE + R +EEE R QQL+ E++ +Q L E+QL E+
Sbjct: 905 EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEA 964
Query: 401 LRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR----EQRLKREQEERRD 456
R++ QL + + ++L E + +Q + +++ E R L E+E+ ++
Sbjct: 965 ARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN 1024
Query: 457 W--LKREEETERHEQE-RRKQQLKRDQEEERRERWLKLEEEERRE-------QQERREQQ 506
LK + E+ E E R K++ K QE E+ +R L+ + + E Q + Q
Sbjct: 1025 LTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQ 1084
Query: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL-LKREEEKRLEQERRE- 564
L +++EE + + +E + L+ ++L + +E L +R + E+++R+
Sbjct: 1085 LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDL 1144
Query: 565 ----QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620
+ LK E E+ D ++E R KREQE + ++ EE R + + +E R
Sbjct: 1145 GEELEALKTELEDTLDSTATQQE----LRAKREQEVTVLKKALDEET-RSHEAQVQEMRQ 1199
Query: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQ-RLKREHEEE 679
K + EE +QL EQ +R + L + +Q ++ E L Q + + EH+++
Sbjct: 1200 KHAQAVEELTEQL----EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKK 1255
Query: 680 RREQELAE-----EEQEQARERIKSRIPKWQWQLES------EADARQSKVYS-----RP 723
+ E ++ E + E+AR + ++ K Q ++ES EA+ + K+
Sbjct: 1256 KLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSS 1315
Query: 724 RKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQR 783
+ Q+ Q QE+ ++ ++L+ EEER Q Q +E + +A++ ER
Sbjct: 1316 QLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDE-------EMEAKQNLERHIST 1368
Query: 784 LSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRR 843
L+ QL +++ ++ E E+ ++R Q+ Q+ E+ +
Sbjct: 1369 LNI----------QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1418
Query: 844 ERAQ-QLQEEEDGLQEDQERRR---SQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQL 899
E+ + +LQ+E D L D + +R S +++ +K+ L EE+ + E+
Sbjct: 1419 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKN------ISSKYADERD 1472
Query: 900 RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959
R E + ++E + L + + +E R + L+ E E L+ + + + +
Sbjct: 1473 RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK 1532
Query: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR------EEREKRRR 1013
++ + Q +E + EE E + + K R E +Q + Q R E+ E++RR
Sbjct: 1533 SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1592
Query: 1014 QEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRR 1073
Q + + + EL+ E +Q K++L E ++ E Q + + G E ++
Sbjct: 1593 QLQRQLHEYETELEDERKQRALAAAAKKKL---EGDLKDLE--LQADSAIKGREEAIKQL 1647
Query: 1074 QELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRR 1133
++L+ Q K+ + + E+ + R+E ++ ++ E +L Q +E L ER R++
Sbjct: 1648 RKLQAQ-MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER-ARKQ 1705
Query: 1134 QELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQ 1193
+LE++ EE + ++ EKRR + Q EE E +Q + + + K Q
Sbjct: 1706 ADLEKEELAEELASSLSGRNALQD-EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1764
Query: 1194 ERERQYRE---EEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQF 1250
+ E+ E E ++ R + E Q +L+ + E E AV+ +
Sbjct: 1765 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH-EMEGAVKSKFKSTIAALEAKI 1823
Query: 1251 RQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE-------EEQLEREE 1303
QLE+ EQ+ R+++ + +Q+D+ E E ++ +
Sbjct: 1824 AQLEEQV---------------EQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY 1868
Query: 1304 QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE 1350
+++A++ + + ++ K+ L E EE +R RK + E E E
Sbjct: 1869 KEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNE 1915
Score = 213 bits (543), Expect = 1e-54
Identities = 273/1151 (23%), Positives = 522/1151 (45%), Gaps = 146/1151 (12%)
Query: 518 RLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQ 577
++ RQEEE Q E Q +E++++ E LK E+K Q E+ L +EQ + +
Sbjct: 846 QVTRQEEE---MQAKEDELQKTKERQQKAENELKELEQKH-SQLTEEKNLLQEQLQAETE 901
Query: 578 LLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSE 637
L EE R + ++QE LE+ L E RLE+EE R Q+L+ E ++ QQ+L E
Sbjct: 902 LYAEAEEMRVRLAAKKQE--LEEILHEMEA-RLEEEEDRGQQLQAER--KKMAQQMLDLE 956
Query: 638 EQEERRQQQLRREQQER--REQRLKREEEEERL--EQRLKREHEEERREQELAEEEQEQA 693
EQ E + ++ Q E+ E ++K+ E+E + +Q K E + E+ +++ A
Sbjct: 957 EQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1016
Query: 694 RERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEER 753
E K+ K +L+++ ++ S++ R +K+E + RQE E+ +R+ E + E+
Sbjct: 1017 EEEEKA---KNLTKLKNKHESMISELEVRLKKEE--KSRQELEKLKRKLEGDASDFHEQI 1071
Query: 754 AHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPE 813
A Q Q E + + EE+ + RL + +++R + E
Sbjct: 1072 ADLQAQIAELKMQLA---KKEEELQAALARLDDEIAQKNNALKKIR-----ELEGHISDL 1123
Query: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQK 873
+E+ + R R + EK+ + L EE + + E L++ D QE R +EQ
Sbjct: 1124 QEDLDSERAARNKAEKQKRDLGEELEALKTE----LEDTLDSTATQQELRAKREQEVTVL 1179
Query: 874 WRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREE 933
+ EE R +QE +K Q ++E E+L++ +R K + +
Sbjct: 1180 KKALDEETRSHEAQ-------VQEMRQKHAQAVEELTEQLEQFKRAKANLD------KNK 1226
Query: 934 EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE 993
+ L++E L E R + ++ +K + Q +E Q + E+ R + +K ++ +
Sbjct: 1227 QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1286
Query: 994 EELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREE 1053
E++ L E E + + + +LQ +E L E R+K + + RQ EE
Sbjct: 1287 NEVESVTGML--NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEE 1344
Query: 1054 EELQQEEEQLLGEERETRRRQE---------LERQYRKEEELQQEEEQLLREEPEKRRRQ 1104
Q++ L EE E ++ E L +K ++ E L EE +KR ++
Sbjct: 1345 RNSLQDQ---LDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEAL--EEGKKRFQK 1399
Query: 1105 ERERQCREEEE--------------LQQEEEQLLRE-EREKRRRQELERQYREEEEVQQE 1149
E E ++ EE LQQE + L+ + + +++ LE++ R+ +++ E
Sbjct: 1400 EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1459
Query: 1150 EEQLLREEPEKRRRQELERQYRE----------EEELQQEEE-----QLLREEQEKRRQE 1194
E+ + + ++R R E E + +E EE L+ +EE ++L+ E E
Sbjct: 1460 EKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSS 1519
Query: 1195 RERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKE-NAVRDNKVYCKGRENEQFRQL 1253
++ + EL++ KR + E+ ++ L+ E E E A D K+ + Q
Sbjct: 1520 KDDVGKNVHELEKSKRALETQMEEMKTQLE---ELEDELQATEDAKLRLEVNMQALKGQF 1576
Query: 1254 E-DSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLERE---------- 1302
E D Q RD Q+++ + L + E + E E R +QR +++LE +
Sbjct: 1577 ERDLQARDEQNEEKRRQLQRQLHEYETELEDER-KQRALAAAAKKKLEGDLKDLELQADS 1635
Query: 1303 ---EQKEAKRRDRKSQEEKQLLREEREEKRRRQ--------ETDRKFREEEQLLQEREEQ 1351
++EA ++ RK Q + + + E E+ R + E ++K + E L + +E
Sbjct: 1636 AIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1695
Query: 1352 PLRRQERDRKFRE-------EELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQER 1404
L ER RK + EEL GR L++E+R E + + E++L ++
Sbjct: 1696 -LAAAERARKQADLEKEELAEELASSLSGRNALQDEKR----RLEARIAQLEEELEEEQG 1750
Query: 1405 EQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFR 1464
+ DR RK ++ +QLS + + ++ + RQ+ ER + ++LR + H
Sbjct: 1751 NMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER----QNKELRSKLH---- 1802
Query: 1465 EEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFL----EE 1520
E E ++ + + + E K + E+Q+ ++ R+++ + L+ ++ + K + E+
Sbjct: 1803 EMEGAVKSKFKSTIAALEA--KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1860
Query: 1521 EQQLHRQQRQR--KFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERD 1578
E+++ Q +++ K +QL+RQ ++ ++ R +L++E +E S +
Sbjct: 1861 ERKMAEQYKEQAEKGNARVKQLKRQL--EEAEEESQRINANRRKLQRELDEATESNEAMG 1918
Query: 1579 RKFRLEEQKVR 1589
R+ + K+R
Sbjct: 1919 REVNALKSKLR 1929
Score = 201 bits (510), Expect = 8e-51
Identities = 260/1122 (23%), Positives = 515/1122 (45%), Gaps = 125/1122 (11%)
Query: 91 QATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAE 150
Q T +EE +A KE LQ + +E Q++ E ++LE++ Q +K QE+ AE
Sbjct: 846 QVTRQEEEMQA----KEDELQ--KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 899
Query: 151 GEEQSEKQE-RLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHET----EEFP 205
E +E +E R+ +++ EE+ + + E EE R ++ Q + K + EE
Sbjct: 900 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL 959
Query: 206 DEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265
+EE+ R++L K E + ++ E + V ++ K L KE + L+E
Sbjct: 960 EEEEAARQKL--QLEKVTAEAKIKKLEDEILVMDDQNNK--------LSKERKLLEERIS 1009
Query: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ---EERR 322
L EEEE+ + L + + + E E + RL++E++ R++ E+ +R+ + +
Sbjct: 1010 DLTTNLAEEEEKAKNLTKLKNKHESMISE-LEVRLKKEEKSRQELEKLKRKLEGDASDFH 1068
Query: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQ 382
EQ + Q + QL +++EE + R + E ++ L++ +E E L+ +
Sbjct: 1069 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLD 1128
Query: 383 LRREQQLRREQQLRREQQLRREQQLRREQQL-----RREQQLRREQQ---LRREQEEERH 434
R + + E+Q R + + E L ++E + +REQ+ L++ +EE
Sbjct: 1129 SERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEE-- 1186
Query: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQ-ERRKQQLKRDQEEERRER------ 487
+ HE + +E R K Q EE TE+ EQ +R K L ++++ +E
Sbjct: 1187 TRSHEAQVQEMRQKHAQAV-------EELTEQLEQFKRAKANLDKNKQTLEKENADLAGE 1239
Query: 488 -----WLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
K E E ++++ E + Q+L+ + + R + ++ +LQ + S + E
Sbjct: 1240 LRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEA 1299
Query: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRD---QLLKREEERR--QQRLKREQE-- 595
E + +L K + + ++ L+ E ++ + +L + EEER Q +L E E
Sbjct: 1300 EGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAK 1359
Query: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ--EERRQQQLRREQQE 653
+ LE+ + ++ + +++ + E EE +++ K E ++ ++ ++ E
Sbjct: 1360 QNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLE 1419
Query: 654 RREQRLKREEEE-----ERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQL 708
+ + RL++E ++ + Q + +++R+ +L EE + I S+ + +
Sbjct: 1420 KTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE-----KNISSKYADERDRA 1474
Query: 709 ESEADARQSKVYSRPRK-QEGQRRRQEQEEKRRRRESELQ------------WQEEERAH 755
E+EA +++K S R +E ++E E + ++E++ E E++
Sbjct: 1475 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1534
Query: 756 R--QQQEEEQRRDFTWQWQAEEKSERGRQRLSAR-PPLREQRERQLRA-----EERQQRE 807
R + Q EE + + +E + RL L+ Q ER L+A EE++++
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQL 1594
Query: 808 QRFLPE-EEEKEQRRRQR-------REREKELQFLE--EEEQLQRRERA-QQLQEEEDGL 856
QR L E E E E R+QR ++ E +L+ LE + ++ RE A +QL++ + +
Sbjct: 1595 QRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQM 1654
Query: 857 QEDQERRRSQEQRRDQKWRWQLEEERKRRR-----HTLYAKPALQEQLRKEQQLLQEE-E 910
++ Q RD+ + E E+K + L A E+ RK+ L +EE
Sbjct: 1655 KDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA 1714
Query: 911 EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKE 970
EEL + Q+++R R E ++ Q EE+L E+ +R R K Q+
Sbjct: 1715 EELASSLSGRNALQDEKR--RLEARIAQLEEELEEEQGNMEAMSDRVR------KATQQA 1766
Query: 971 EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKD-ELQQE 1029
EQL E +R ++ + R++ E Q +E + E E + +++ + ++ Q
Sbjct: 1767 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1826
Query: 1030 EEQLLREEREK----RRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
EEQ+ +E REK + L++++++ + E LQ E+E+ + E+ + + + R + + +
Sbjct: 1827 EEQVEQEAREKQAATKSLKQKDKKLK-EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQ 1885
Query: 1086 LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127
L++ EE+ R +R+ Q + E E E L+ +
Sbjct: 1886 LEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1927
Score = 200 bits (508), Expect = 1e-50
Identities = 256/1143 (22%), Positives = 523/1143 (45%), Gaps = 124/1143 (10%)
Query: 833 FLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAK 892
F + + LQ + +++Q +ED LQ+ +ER++ E +L+E ++ K
Sbjct: 838 FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAEN--------ELKELEQKHSQLTEEK 889
Query: 893 PALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRR 952
LQEQL+ E +L E EE R +K+ E E++ E E L EE ++ +
Sbjct: 890 NLLQEQLQAETELYAEAEEMRVRLAAKKQ----------ELEEILHEMEARLEEEEDRGQ 939
Query: 953 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1012
+ + ER+ + L +E+ L EE R++ + EK E + + E+E L+ +++ +
Sbjct: 940 QLQAERKKMAQQMLDLEEQ--LEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKL 997
Query: 1013 RQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRR 1072
+E + + +L L EE EK + + + + E + + E +L EE+
Sbjct: 998 SKERKLLEERISDLTTN----LAEEEEKAKNLTKLKN-KHESMISELEVRLKKEEKS--- 1049
Query: 1073 RQELERQYRK-EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE----EEQLLREE 1127
RQELE+ RK E + EQ+ + + + + + + ++EEELQ ++++ ++
Sbjct: 1050 RQELEKLKRKLEGDASDFHEQIA--DLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1107
Query: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRR---QELERQYREEEEL-----QQE 1179
++ +ELE + +E + E+ R + EK++R +ELE E E+ Q+
Sbjct: 1108 NALKKIRELEGHISDLQE-DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQ 1166
Query: 1180 EEQLLREEQ----EKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV 1235
E + RE++ +K E R + + + RQK Q + ++ + Q++ K N
Sbjct: 1167 ELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE---QFKRAKANLD 1223
Query: 1236 RDNKVYCKGREN--EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHF 1293
++ + K + + R L ++ ++ L+ + E Q + + ER R + D+
Sbjct: 1224 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1283
Query: 1294 PEEEQLER-------------EEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE 1340
+ ++E + K+ + Q+ ++LL+EE +K R+ E
Sbjct: 1284 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1343
Query: 1341 EEQLLQER-EEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR-QERERKFLKEEQQ 1398
E LQ++ +E+ +Q +R ++ + +K + + +E +++F KE +
Sbjct: 1344 ERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN 1403
Query: 1399 LRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQE 1458
L Q E+ D K + + +L ++ D + Q+ E+K + +Q L +E
Sbjct: 1404 LTQQYEEKAAAYD---KLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1460
Query: 1459 RH--RKFREE----EQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQE 1512
++ K+ +E E +E+E + L + LE +++L R + K ++L S +
Sbjct: 1461 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSK 1520
Query: 1513 PERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQL 1572
+ + +H ++ ++ L+ + + + + Q + + + E+ +LR E Q L
Sbjct: 1521 DD-----VGKNVHELEKSKRALETQME---EMKTQLEELEDELQATEDAKLRLEVNMQAL 1572
Query: 1573 SRQ-ERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQER 1631
Q ERD + R E+ + +R++ +R+ E E +L + Q+ L +K D + L+ +
Sbjct: 1573 KGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ 1632
Query: 1632 EEQQLH-RQERDRKFLEEEPQLRRQERE-QQLRHDRDRKF---REEEQLLQEGE------ 1680
+ + R+E ++ + + Q++ +RE + R RD F +E E+ + E
Sbjct: 1633 ADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQL 1692
Query: 1681 EQQLRRQERDRKFREEEQQLRRQERE-----RKFLQEEQ---QLRRQELERKFREEE--- 1729
++ L ER RK + E++ +E R LQ+E+ + R +LE + EE+
Sbjct: 1693 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM 1752
Query: 1730 -----QLRQETEQ-EQLRRQERYRKILEEEQLRPEREEQQLRRQERD--RKFREEEQLRQ 1781
++R+ T+Q EQL + + ++ E QQL RQ ++ K E E +
Sbjct: 1753 EAMSDRVRKATQQAEQLSNELATERSTAQKN---ESARQQLERQNKELRSKLHEMEGAVK 1809
Query: 1782 EREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQER 1841
+ + + + E+ EE+ ++ RE+Q + + +E LQ+E++ + Q +
Sbjct: 1810 SKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYK 1869
Query: 1842 DRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEI 1901
+ +AE+ A ++ +R+ +E EEE +R RKL+ E + E R+V +
Sbjct: 1870 E---QAEKGNARVKQLKRQLEE--AEEESQRINANRRKLQRELDEATESNEAMGREVNAL 1924
Query: 1902 KSQ 1904
KS+
Sbjct: 1925 KSK 1927
Score = 200 bits (508), Expect = 1e-50
Identities = 262/1108 (23%), Positives = 513/1108 (46%), Gaps = 155/1108 (13%)
Query: 213 RELLELRR-----KGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR 267
+ LL++ R + +E++ Q+ +ERQ + E E KE ++ + L EE+ L +E+ Q
Sbjct: 842 KPLLQVTRQEEEMQAKEDELQKTKERQQKA--ENELKELEQKHSQL-TEEKNLLQEQLQA 898
Query: 268 QRELQEEEEQLR------KLERQELRRER----QEEEQQQQRLRREQQLRRKQEEERREQ 317
+ EL E E++R K E +E+ E +EEE + Q+L+ E++ +Q + EQ
Sbjct: 899 ETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ 958
Query: 318 QEERREQQERREQQEERREQQLRREQEE-----RREQQLRREQE--EERREQQLRREQEE 370
EE +++ + ++ E ++++ ++E + +L +E++ EER EE
Sbjct: 959 LEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1018
Query: 371 ERREQQLRREQQLRREQQLRREQQLRREQQLRRE-QQLRREQQ---LRREQQLRREQQLR 426
E + + L + + E +L++E++ R+E ++L+R+ + +Q+ Q
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078
Query: 427 REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRE 486
E + + +++ E + RL E ++ + LK+ E E H + L+ D + ER
Sbjct: 1079 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISD-----LQEDLDSERAA 1133
Query: 487 RWLKLEEEERREQQERREQQLRREQEE-------RREQRLKRQEEEERLQQRLRSE---- 535
R E+++R+ E E L+ E E+ ++E R KR++E L++ L E
Sbjct: 1134 R--NKAEKQKRDLGEELE-ALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH 1190
Query: 536 ----QQLRREQEERREQLLKREEE---KRLEQERREQRLKREQEERRDQL-----LKREE 583
Q++R++ + E+L ++ E+ + ++ +Q L++E + +L K+E
Sbjct: 1191 EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEV 1250
Query: 584 ERRQQRLKREQEERLE-----QRLKRE---EVERLEQE---------ERREQRLKREEPE 626
E ++++L+ + +E +R + E +V +L+ E E + +K +
Sbjct: 1251 EHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1310
Query: 627 EERRQQLLKSEE--QEERRQQ-----QLRREQQERREQRLKREEEEERLEQRLKRE---- 675
QL ++E QEE RQ+ +LR+ ++ER + + +EE E +Q L+R
Sbjct: 1311 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME-AKQNLERHISTL 1369
Query: 676 ----HEEERREQELAE--EEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ--- 726
+ +++ Q+ A E E+ ++R + I Q E +A A ++ R Q
Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL 1429
Query: 727 -------EGQRRRQEQEEKRRRRESELQWQEE----------ERAHRQQQEEEQR----- 764
+ QR+ EK++R+ +L +E+ +RA + +E+E +
Sbjct: 1430 DDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLA 1489
Query: 765 RDFTWQWQAEEKSERGRQRLSAR-PPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQ 823
R +A+E+ ER + L A L ++ + ++ +R L E + E+ + Q
Sbjct: 1490 RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL--ETQMEEMKTQ 1547
Query: 824 RREREKELQFLEEEE-QLQRRERAQQLQEEED--GLQEDQERRRSQEQRRDQKWRWQLEE 880
E E ELQ E+ + +L+ +A + Q E D E E +R Q QR+ ++ +LE+
Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELED 1607
Query: 881 ERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEE 940
ERK+R AK L+ L+ + LQ + REE K+ R+ Q + ++ Q + E+
Sbjct: 1608 ERKQRALAAAAKKKLEGDLKDLE--LQADSAIKGREEAIKQLRKLQAQM--KDFQRELED 1663
Query: 941 EQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEE 1000
+ R+E ++ ++ + L Q +E L E + R++ E+EEL +E
Sbjct: 1664 ARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE------RARKQADLEKEELAEEL 1717
Query: 1001 EQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEE 1060
L R + + R + + Q EE+L E+ + +R R+ ++ E E
Sbjct: 1718 ASSL-----SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1772
Query: 1061 EQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEE 1120
L ER T ++ E RQ + E +E L E + + + E ++ Q E
Sbjct: 1773 ---LATERSTAQKNESARQ--QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLE 1827
Query: 1121 EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE 1180
EQ+ +E REK+ + +Q + ++ +E LL+ E E++ + QY+E+ E
Sbjct: 1828 EQVEQEAREKQAATKSLKQ-----KDKKLKEILLQVEDERK----MAEQYKEQAEKGNAR 1878
Query: 1181 EQLLREEQEKRRQERERQYREEEELQRQ 1208
+ L+ + E+ +E +R +LQR+
Sbjct: 1879 VKQLKRQLEEAEEESQRINANRRKLQRE 1906
Score = 188 bits (478), Expect = 4e-47
Identities = 250/1153 (21%), Positives = 513/1153 (44%), Gaps = 131/1153 (11%)
Query: 680 RREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQE--QEE 737
+R+Q+L + Q ++ WQW + + R++E + +++ Q+
Sbjct: 808 KRQQQLTAMKVIQRNCAAYLKLRNWQWW---RLFTKVKPLLQVTRQEEEMQAKEDELQKT 864
Query: 738 KRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAE--EKSERGRQRLSARPPLREQ-- 793
K R++++E + +E E+ H Q EE+ Q + E ++E R RL+A+ E+
Sbjct: 865 KERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEIL 924
Query: 794 RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
E + R EE + R Q+ E ++ Q+ E+ +E + ++ QL++ ++++ E
Sbjct: 925 HEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLE 984
Query: 854 DGL--QEDQERRRSQEQR----RDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQ 907
D + +DQ + S+E++ R L EE ++ ++ K + + + + L+
Sbjct: 985 DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK 1044
Query: 908 EEEEELQREEREKRRRQEQERQYREE-----EQLQQEEEQLLREERE-----KRRRQERE 957
+EE+ Q E+ KR+ + + E+ Q+ + + QL ++E E R E
Sbjct: 1045 KEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIA 1104
Query: 958 RQYRKDKKLQQKEEQLLG-EEPEKRRRQEREKKYREEEELQQEEEQLLRE---------- 1006
++ KK+++ E + +E R R K +++ +L +E E L E
Sbjct: 1105 QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTAT 1164
Query: 1007 EREKRRRQEWERQYRKK--DELQQEEEQLLREEREKR-----RLQERERQYRE------- 1052
++E R ++E E KK DE + E ++E R+K L E+ Q++
Sbjct: 1165 QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK 1224
Query: 1053 -EEELQQEEEQLLGEERET-RRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQC 1110
++ L++E L GE R + +QE+E + +K+ E Q +E Q + E+ R + ++
Sbjct: 1225 NKQTLEKENADLAGELRVLGQAKQEVEHK-KKKLEAQVQELQSKCSDGERARAELNDKVH 1283
Query: 1111 REEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQY 1170
+ + E++ L E + + L + Q+ ++LL+EE R++ + +
Sbjct: 1284 KLQNEVESVTGMLNEAEGKAIK---LAKDVASLSSQLQDTQELLQEET--RQKLNVSTKL 1338
Query: 1171 RE-EEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDE-DQRSDLKWQWE 1228
R+ EEE ++QL E + K+ ER + +K+ Q + + + K +++
Sbjct: 1339 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1398
Query: 1229 PEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE--RDREQERRRW 1286
E EN + + + + +LE ++ R +Q DL L Q++ + E+++R++
Sbjct: 1399 KEIENLTQQYE-----EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKF 1453
Query: 1287 QQ---RDRHFPEEEQLEREE-QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREE- 1341
Q +++ + ER+ + EA+ ++ K+ + L E E K + T++ + E
Sbjct: 1454 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1513
Query: 1342 EQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRC 1401
E L+ +++ E ++ R E + +E + E E L+ E + +LR
Sbjct: 1514 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE--------DAKLRL 1565
Query: 1402 QEREQQLRQ--DRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQER 1459
+ Q L+ +RD + R+E+ + R++ R+ E E ++ ER+++ L + + E
Sbjct: 1566 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELE-DERKQRALAAAAKKKLEG 1624
Query: 1460 HRKFRE--EEQLLQEREE--QQLHRQERDRKFLEEEQQLRRQERDRKF---REQELRSQE 1512
K E + ++ REE +QL + + K + E + R RD F +E E +++
Sbjct: 1625 DLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1684
Query: 1513 PERKFLEEEQQLHRQQRQRKFLQEEQQLRRQE-----RGQQRRQDRDRKFRE-----EEQ 1562
E ++ ++ L +R RK E++ +E G+ QD R+ EE+
Sbjct: 1685 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE 1744
Query: 1563 LRQER---------------EEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQ 1607
L +E+ + +QLS + + ++ + RQ+ ER+ E +L
Sbjct: 1745 LEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEM 1804
Query: 1608 EGQQQLRQERDRKFRE------DEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQL 1661
EG + + + E +EQ+ QE E+Q + +K + + L + E E+++
Sbjct: 1805 EGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKM 1864
Query: 1662 RHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQEL 1721
EQ ++ E+ R ++ R+ E E++ +R R+ LQ E +
Sbjct: 1865 ----------AEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESN 1914
Query: 1722 ERKFREEEQLRQE 1734
E RE L+ +
Sbjct: 1915 EAMGREVNALKSK 1927
Score = 107 bits (267), Expect = 1e-22
Identities = 131/594 (22%), Positives = 267/594 (44%), Gaps = 65/594 (10%)
Query: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRK 1415
+ERD K + + Q R +L + +RQ++ + Q C + R
Sbjct: 780 EERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAM--KVIQRNCAAYLKLRNWQWWRL 837
Query: 1416 FREEEQ--QLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE- 1472
F + + Q++RQE + + +E+E Q + +ER++K E ++L Q +H + EE+ LLQE
Sbjct: 838 FTKVKPLLQVTRQEEEMQAKEDELQ-KTKERQQKAENELKELEQ-KHSQLTEEKNLLQEQ 895
Query: 1473 -REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR 1531
+ E +L+ + + + ++QE + E E R +E E + ++ Q R++ +
Sbjct: 896 LQAETELYAEAEE---MRVRLAAKKQELEEILHEMEARLEEEEDR--GQQLQAERKKMAQ 950
Query: 1532 KFLQEEQQLRRQERGQQRRQ------DRDRKFREEEQLRQEREEQQLSRQERDRKFRLEE 1585
+ L E+QL +E +Q+ Q + K E+E L + + +LS++ + + R+ +
Sbjct: 951 QMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1010
Query: 1586 QKVRRQEQERKFMEDEQQLRRQE---GQQQLRQERDRKFREDEQLLQ---EREEQQLHRQ 1639
E+E K + + E + ++R +++ K R++ + L+ E + H Q
Sbjct: 1011 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1070
Query: 1640 ERD--RKFLEEEPQLRRQEREQQLRHDR-DRKFREEEQLLQEGEEQQLRRQERDRKFREE 1696
D + E + QL ++E E Q R D + ++ L++ E + + E
Sbjct: 1071 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1130
Query: 1697 EQQLRRQERERKFLQEEQQLRRQELERKF---REEEQLRQETEQEQLRRQERYRKILEEE 1753
+ E++++ L EE + + ELE +++LR + EQE +K L+EE
Sbjct: 1131 RAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQE----VTVLKKALDEE 1186
Query: 1754 QLRPEREEQQLRRQERDRKFREEEQLRQ--------EREEQQLRSQESD----------- 1794
E + Q++R++ EQL Q ++ +Q L + +D
Sbjct: 1187 TRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQA 1246
Query: 1795 RKFREEEQLRQEREEQQLRPQQRDGKY-------RWEEEQLQLEEQEQRLRQERDRQYRA 1847
++ E ++ + E + Q+L+ + DG+ + + Q ++E L + + +
Sbjct: 1247 KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKL 1306
Query: 1848 EEQFATQEKSRREEQELWQEEEQKRR--QERERKLREEH--IRRQQKEEQRHRQ 1897
+ A+ ++ QEL QEE +++ + R+L EE ++ Q EE +Q
Sbjct: 1307 AKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1360
Score = 106 bits (265), Expect = 2e-22
Identities = 104/492 (21%), Positives = 231/492 (46%), Gaps = 30/492 (6%)
Query: 116 EEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWR 175
E D+ E R+++ + R ++ E + EL E++ K + E D +++ +
Sbjct: 1470 ERDRAEAEAREKETKALSLARALEEALEAKEEL----ERTNKMLKAEMEDLVSSKDDVGK 1525
Query: 176 QRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQD 235
E ++ +RA E Q++ K + EE DE Q L L + K Q R+ Q
Sbjct: 1526 NVHELEK--SKRALETQMEEMKT-QLEELEDELQATEDAKLRLEVNMQALKGQFERDLQA 1582
Query: 236 RVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR------QRELQEEEEQLRKLERQELRRE 289
R Q EE++ +R+ L + E +L++E QR +++L+ + + L +L+ +
Sbjct: 1583 RDEQNEEKRRQLQRQ--LHEYETELEDERKQRALAAAAKKKLEGDLKDL-ELQADSAIKG 1639
Query: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQ 349
R+E +Q ++L+ + + +++ E+ R ++E + E++ + E L + QE+
Sbjct: 1640 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1699
Query: 350 QLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR-EQQLRREQQLRREQQLR 408
+ R+Q + +E+ L E + ++++ R E ++ + E++L EQ R
Sbjct: 1700 ERARKQADLEKEE-LAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1758
Query: 409 REQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHE 468
+ ++ +QL E R ++ + + ER+ + L+ + E +K + ++
Sbjct: 1759 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1818
Query: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 528
E + QL+ E+E RE K + +Q++++ +++ + E+ R+ + +E+ E+
Sbjct: 1819 LEAKIAQLEEQVEQEARE---KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1875
Query: 529 QQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQ 588
R++ QL+R+ EE EE +R+ RR+ + + ++ ++ + RE +
Sbjct: 1876 NARVK---QLKRQLEE------AEEESQRINANRRKLQRELDEATESNEAMGREVNALKS 1926
Query: 589 RLKREQEERLEQ 600
+L+ + Q
Sbjct: 1927 KLRGPPPQETSQ 1938
Score = 89.7 bits (221), Expect = 2e-17
Identities = 97/447 (21%), Positives = 211/447 (47%), Gaps = 38/447 (8%)
Query: 1507 ELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE 1566
++ QE E + E+E Q ++++Q+ E +L+ E Q+ Q + K +EQL+ E
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKA----ENELKELE--QKHSQLTEEKNLLQEQLQAE 899
Query: 1567 REEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQ-QQLRQERDRKFREDE 1625
E L + + + RL +K QE E E E +L +E + QQL+ ER + ++
Sbjct: 900 TE---LYAEAEEMRVRLAAKK---QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 953
Query: 1626 QLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR 1685
L ++ EE++ RQ+ + + E ++++ E E + D++ K +E +LL+E R
Sbjct: 954 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEE------R 1007
Query: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQ-- 1743
+ EEE++ + + L+ + + ELE + ++EE+ RQE E+ + + +
Sbjct: 1008 ISDLTTNLAEEEEKAKNLTK----LKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 1063
Query: 1744 -ERYRKILEEEQLRPEREEQQLRRQERDRK---FREEEQLRQEREE-QQLRSQESDRKFR 1798
+ + + + Q + + QL ++E + + R ++++ Q+ +++R E
Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDL 1123
Query: 1799 EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSR 1858
+E+ + + Q+RD E + +LE+ +++ + + E++ +K+
Sbjct: 1124 QEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKAL 1183
Query: 1859 REEQELWQEEEQKRRQERERKLRE-----EHIRRQQKEEQRHRQVGEIKSQEGKGHGRLL 1913
EE + + Q+ RQ+ + + E E +R + +++Q E ++ + G R+L
Sbjct: 1184 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1243
Query: 1914 EPGTHQFASVPVRSSPLYEYIQEQRSQ 1940
+ V + L +QE +S+
Sbjct: 1244 GQAKQE---VEHKKKKLEAQVQELQSK 1267
Score = 65.1 bits (157), Expect = 6e-10
Identities = 64/274 (23%), Positives = 126/274 (45%), Gaps = 31/274 (11%)
Query: 1643 RKFLEEEP--QLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQL 1700
R F + +P Q+ RQE E Q + D +K +E +Q + E + +++ + EE+ L
Sbjct: 836 RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQ---KAENELKELEQKHSQLTEEKNLL 892
Query: 1701 RRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPERE 1760
+ Q + L E + R L K +E E++ E E ++R +QL+ ER+
Sbjct: 893 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDR------GQQLQAERK 946
Query: 1761 EQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGK 1820
+ + + + + EEE RQ+ + +++ ++ +K E+E L + + +L +++ +
Sbjct: 947 KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL-EDEILVMDDQNNKLSKERKLLE 1005
Query: 1821 YRWEEEQLQLEEQEQRLRQERDRQYRAEEQFAT-------QEKSRREEQELWQEEEQKRR 1873
R + L E+E++ + + + E + +EKSR+E ++L KR+
Sbjct: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKL------KRK 1059
Query: 1874 QERERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
E + E I Q Q+ E+K Q K
Sbjct: 1060 LEGDASDFHEQIADLQ------AQIAELKMQLAK 1087
Score = 34.3 bits (77), Expect = 1.2
Identities = 22/107 (20%), Positives = 48/107 (44%), Gaps = 19/107 (17%)
Query: 1821 YRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKL 1880
++W +++ Q RQE + Q + +E T+E+ ++ E EL + E++ + E+ L
Sbjct: 832 WQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNL 891
Query: 1881 REEHI-------------------RRQQKEEQRHRQVGEIKSQEGKG 1908
+E + ++Q+ EE H ++ +E +G
Sbjct: 892 LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 938
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.127 0.330
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,308,565
Number of Sequences: 37866
Number of extensions: 6046032
Number of successful extensions: 826153
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2132
Number of HSP's successfully gapped in prelim test: 1400
Number of HSP's that attempted gapping in prelim test: 56902
Number of HSP's gapped (non-prelim): 183746
length of query: 1943
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1826
effective length of database: 13,817,196
effective search space: 25230199896
effective search space used: 25230199896
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.