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Search of human proteins with 148746183
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148746183 ubiquitin specific protease 35 [Homo sapiens]
(1018 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148746183 ubiquitin specific protease 35 [Homo sapiens] 2050 0.0
gi|27545313 ubiquitin specific peptidase 38 [Homo sapiens] 576 e-164
gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens] 87 8e-17
gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens] 87 8e-17
gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sap... 85 3e-16
gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapi... 85 3e-16
gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens] 76 2e-13
gi|62243586 ubiquitin-specific protease 21 [Homo sapiens] 72 2e-12
gi|74027267 ubiquitin-specific protease 21 [Homo sapiens] 72 2e-12
gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens] 72 3e-12
gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens] 71 5e-12
gi|239742285 PREDICTED: hypothetical protein XP_002342486 [Homo ... 71 6e-12
gi|169217654 PREDICTED: similar to deubiquitinating enzyme DUB1 ... 70 1e-11
gi|239758075 PREDICTED: similar to deubiquitinating enzyme DUB1 ... 70 1e-11
gi|239742297 PREDICTED: hypothetical protein XP_002342480 [Homo ... 70 1e-11
gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens] 70 1e-11
gi|157785653 ubiquitin specific peptidase 17 [Homo sapiens] 70 1e-11
gi|113415490 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 69 2e-11
gi|113415488 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 69 2e-11
gi|113415486 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 69 2e-11
gi|113415484 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 69 2e-11
gi|113415480 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 69 2e-11
gi|113415478 PREDICTED: similar to deubiquitinating enzyme 1 [Ho... 69 2e-11
gi|113415476 PREDICTED: similar to deubiquitinating enzyme 3 [Ho... 69 2e-11
gi|239742295 PREDICTED: hypothetical protein XP_002342479 [Homo ... 69 2e-11
gi|239742293 PREDICTED: hypothetical protein XP_002342478 [Homo ... 69 2e-11
gi|239742280 PREDICTED: hypothetical protein XP_002342473 [Homo ... 69 2e-11
gi|239742291 PREDICTED: hypothetical protein XP_002342477 [Homo ... 69 2e-11
gi|239742289 PREDICTED: hypothetical protein XP_002342476 [Homo ... 69 2e-11
gi|239742278 PREDICTED: hypothetical protein XP_002342472 [Homo ... 69 2e-11
>gi|148746183 ubiquitin specific protease 35 [Homo sapiens]
Length = 1018
Score = 2050 bits (5311), Expect = 0.0
Identities = 1018/1018 (100%), Positives = 1018/1018 (100%)
Query: 1 MDKILEAVVTSSYPVSVKQGLVRRVLEAARQPLEREQCLALLALGARLYVGGAEELPRRV 60
MDKILEAVVTSSYPVSVKQGLVRRVLEAARQPLEREQCLALLALGARLYVGGAEELPRRV
Sbjct: 1 MDKILEAVVTSSYPVSVKQGLVRRVLEAARQPLEREQCLALLALGARLYVGGAEELPRRV 60
Query: 61 GCQLLHVAGRHHPDVFAEFFSARRVLRLLQGGAGPPGPRALACVQLGLQLLPEGPAADEV 120
GCQLLHVAGRHHPDVFAEFFSARRVLRLLQGGAGPPGPRALACVQLGLQLLPEGPAADEV
Sbjct: 61 GCQLLHVAGRHHPDVFAEFFSARRVLRLLQGGAGPPGPRALACVQLGLQLLPEGPAADEV 120
Query: 121 FALLRREVLRTVCERPGPAACAQVARLLARHPRCVPDGPHRLLFCQQLVRCLGRFRCPAE 180
FALLRREVLRTVCERPGPAACAQVARLLARHPRCVPDGPHRLLFCQQLVRCLGRFRCPAE
Sbjct: 121 FALLRREVLRTVCERPGPAACAQVARLLARHPRCVPDGPHRLLFCQQLVRCLGRFRCPAE 180
Query: 181 GEEGAVEFLEQAQQVSGLLAQLWRAQPAAILPCLKELFAVISCAEEEPPSSALASVVQHL 240
GEEGAVEFLEQAQQVSGLLAQLWRAQPAAILPCLKELFAVISCAEEEPPSSALASVVQHL
Sbjct: 181 GEEGAVEFLEQAQQVSGLLAQLWRAQPAAILPCLKELFAVISCAEEEPPSSALASVVQHL 240
Query: 241 PLELMDGVVRNLSNDDSVTDSQMLTAISRMIDWVSWPLGKNIDKWIIALLKGLAAVKKFS 300
PLELMDGVVRNLSNDDSVTDSQMLTAISRMIDWVSWPLGKNIDKWIIALLKGLAAVKKFS
Sbjct: 241 PLELMDGVVRNLSNDDSVTDSQMLTAISRMIDWVSWPLGKNIDKWIIALLKGLAAVKKFS 300
Query: 301 ILIEVSLTKIEKVFSKLLYPIVRGAALSVLKYMLLTFQHSHEAFHLLLPHIPPMVASLVK 360
ILIEVSLTKIEKVFSKLLYPIVRGAALSVLKYMLLTFQHSHEAFHLLLPHIPPMVASLVK
Sbjct: 301 ILIEVSLTKIEKVFSKLLYPIVRGAALSVLKYMLLTFQHSHEAFHLLLPHIPPMVASLVK 360
Query: 361 EDSNSGTSCLEQLAELVHCMVFRFPGFPDLYEPVMEAIKDLHVPNEDRIKQLLGQDAWTS 420
EDSNSGTSCLEQLAELVHCMVFRFPGFPDLYEPVMEAIKDLHVPNEDRIKQLLGQDAWTS
Sbjct: 361 EDSNSGTSCLEQLAELVHCMVFRFPGFPDLYEPVMEAIKDLHVPNEDRIKQLLGQDAWTS 420
Query: 421 QKSELAGFYPRLMAKSDTGKIGLINLGNTCYVNSILQALFMASDFRHCVLRLTENNSQPL 480
QKSELAGFYPRLMAKSDTGKIGLINLGNTCYVNSILQALFMASDFRHCVLRLTENNSQPL
Sbjct: 421 QKSELAGFYPRLMAKSDTGKIGLINLGNTCYVNSILQALFMASDFRHCVLRLTENNSQPL 480
Query: 481 MTKLQWLFGFLEHSQRPAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGT 540
MTKLQWLFGFLEHSQRPAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGT
Sbjct: 481 MTKLQWLFGFLEHSQRPAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGT 540
Query: 541 RICQKLKQSSSPSPPEEPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAF 600
RICQKLKQSSSPSPPEEPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAF
Sbjct: 541 RICQKLKQSSSPSPPEEPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAF 600
Query: 601 PPPERCRRRRLGSVMRPTEDITARELPPPTSAQGPGRVGPRRQRKHCITEDTPPTSLYIE 660
PPPERCRRRRLGSVMRPTEDITARELPPPTSAQGPGRVGPRRQRKHCITEDTPPTSLYIE
Sbjct: 601 PPPERCRRRRLGSVMRPTEDITARELPPPTSAQGPGRVGPRRQRKHCITEDTPPTSLYIE 660
Query: 661 GLDSKEAGGQSSQEERIEREEEGKEERTEKEEVGEEEESTRGEGEREKEEEVEEEEEKVE 720
GLDSKEAGGQSSQEERIEREEEGKEERTEKEEVGEEEESTRGEGEREKEEEVEEEEEKVE
Sbjct: 661 GLDSKEAGGQSSQEERIEREEEGKEERTEKEEVGEEEESTRGEGEREKEEEVEEEEEKVE 720
Query: 721 KETEKEAEQEKEEDSLGAGTHPDAAIPSGERTCGSEGSRSVLDLVNYFLSPEKLTAENRY 780
KETEKEAEQEKEEDSLGAGTHPDAAIPSGERTCGSEGSRSVLDLVNYFLSPEKLTAENRY
Sbjct: 721 KETEKEAEQEKEEDSLGAGTHPDAAIPSGERTCGSEGSRSVLDLVNYFLSPEKLTAENRY 780
Query: 781 YCESCASLQDAEKVVELSQGPCYLILTLLRFSFDLRTMRRRKILDDVSIPLLLRLPLAGG 840
YCESCASLQDAEKVVELSQGPCYLILTLLRFSFDLRTMRRRKILDDVSIPLLLRLPLAGG
Sbjct: 781 YCESCASLQDAEKVVELSQGPCYLILTLLRFSFDLRTMRRRKILDDVSIPLLLRLPLAGG 840
Query: 841 RGQAYDLCSVVVHSGVSSESGHYYCYAREGAARPAASLGTADRPEPENQWYLFNDTRVSF 900
RGQAYDLCSVVVHSGVSSESGHYYCYAREGAARPAASLGTADRPEPENQWYLFNDTRVSF
Sbjct: 841 RGQAYDLCSVVVHSGVSSESGHYYCYAREGAARPAASLGTADRPEPENQWYLFNDTRVSF 900
Query: 901 SSFESVSNVTSFFPKDTAYVLFYRQRPREGPEAELGSSRVRTEPTLHKDLMEAISKDNIL 960
SSFESVSNVTSFFPKDTAYVLFYRQRPREGPEAELGSSRVRTEPTLHKDLMEAISKDNIL
Sbjct: 901 SSFESVSNVTSFFPKDTAYVLFYRQRPREGPEAELGSSRVRTEPTLHKDLMEAISKDNIL 960
Query: 961 YLQEQEKEARSRAAYISALPTSPHWGRGFDEDKDEDEGSPGGCNPAGGNGGDFHRLVF 1018
YLQEQEKEARSRAAYISALPTSPHWGRGFDEDKDEDEGSPGGCNPAGGNGGDFHRLVF
Sbjct: 961 YLQEQEKEARSRAAYISALPTSPHWGRGFDEDKDEDEGSPGGCNPAGGNGGDFHRLVF 1018
>gi|27545313 ubiquitin specific peptidase 38 [Homo sapiens]
Length = 1042
Score = 576 bits (1484), Expect = e-164
Identities = 308/629 (48%), Positives = 416/629 (66%), Gaps = 34/629 (5%)
Query: 1 MDKILEAVVTSSYPVSVKQGLVRRVLEAARQPLEREQCLALLALGARLYVGGAEELPRRV 60
MDKILE +V+SS+P+ +K+ +VR+V+E+A L+ QC A+ L RL + G + R+V
Sbjct: 1 MDKILEGLVSSSHPLPLKRVIVRKVVESAEHWLDEAQCEAMFDLTTRLILEGQDPFQRQV 60
Query: 61 GCQLLHVAGRHHPDVFAEFFSARRVLRLLQGGAGPPGPRALACVQL---GLQLLPEGPAA 117
G Q+L R+H F FF+ VL LL G + +A + GL+L+ P+
Sbjct: 61 GHQVLEAYARYHRPEFESFFNKTFVLGLLHQGYHSLDRKDVAILDYIHNGLKLIMSCPSV 120
Query: 118 DEVFALLRREVLRTVCERPGPAACAQVARLLARHPRCVPDGPHRLLFCQQLVRCLGRFRC 177
++F+LL+ EVLR VCERP P CA+++ LL +C+P G + FCQQLVR +G F+C
Sbjct: 121 LDLFSLLQVEVLRMVCERPEPQLCARLSDLLTDFVQCIPKGKLSITFCQQLVRTIGHFQC 180
Query: 178 PAEGEEGAVEFLEQAQQVSGLLAQLWRAQPAAILPCLKELFAVISCAEEE-PPSSALASV 236
+ E E++ Q +VS LL +W+A+PA +LP L+E+FA IS + PS ALAS+
Sbjct: 181 VSTQERELREYVSQVTKVSNLLQNIWKAEPATLLPSLQEVFASISSTDASFEPSVALASL 240
Query: 237 VQHLPLELMDGVVRNLSNDDSVTDSQMLTAISRMIDWVSWPLGKNIDKWIIALLKGLAAV 296
VQH+PL+++ ++R+L+ D +V D+ M A+ RMIDW+SWPL +++D W+IALLKGLAAV
Sbjct: 241 VQHIPLQMITVLIRSLTTDPNVKDASMTQALCRMIDWLSWPLAQHVDTWVIALLKGLAAV 300
Query: 297 KKFSILIEVSLTKIEKVFSKLLYPIVRGAALSVLKYMLLTFQHSHEAFHLLLPHIPPMVA 356
+KF+ILI+V+L KIE VF++L +P+VR AL+VL +MLL+FQHS EAFHL++PH+ +V
Sbjct: 301 QKFTILIDVTLLKIELVFNRLWFPLVRPGALAVLSHMLLSFQHSPEAFHLIVPHVVNLVH 360
Query: 357 SLVKEDSNSGTSCLEQLAELVHCMVFRFPGFPDLYEPVMEAIKDLHVPNEDRIKQLLGQD 416
S + S T+ L QL EL+HCM++ + GFPDLYEP++EAIKD P+E++IK +L Q
Sbjct: 361 SFKNDGLPSSTAFLVQLTELIHCMMYHYSGFPDLYEPILEAIKDFPKPSEEKIKLILNQS 420
Query: 417 AWTSQKSELAGFYPRLMAKSDTGKIGLINLGNTCYVNSILQALFMASDFRHCVLRLTENN 476
AWTSQ + LA RL KS+TGK GLINLGNTCY+NS++QALFMA+DFR VL L N
Sbjct: 421 AWTSQSNSLASCLSRLSGKSETGKTGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNG 480
Query: 477 SQPLMTKLQWLFGFLEHSQRPAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEE 536
LM KLQ LF FL H+QR A +P F AS PWF+P +QQDCSEYL++LLDRLHEEE
Sbjct: 481 CNSLMKKLQHLFAFLAHTQREAYAPRIFFEASRPPWFTPRSQQDCSEYLRFLLDRLHEEE 540
Query: 537 KTGTRICQKLKQSSSPSPPE--------------------EPPAPS---STSVEKMFGGK 573
K LK +S P E E P S T +EKMFGGK
Sbjct: 541 KI-------LKVQASHKPSEILECSETSLQEVASKAAVLTETPRTSDGEKTLIEKMFGGK 593
Query: 574 IVTRICCLCCLNVSSREEAFTDLSLAFPP 602
+ T I CL C + S + EAFTDLSLAF P
Sbjct: 594 LRTHIRCLNCRSTSQKVEAFTDLSLAFCP 622
Score = 218 bits (555), Expect = 2e-56
Identities = 137/327 (41%), Positives = 178/327 (54%), Gaps = 75/327 (22%)
Query: 754 GSEGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSF 813
G E + SV DL+NYFL+PE LT +N+YYCE+CASLQ+AEK +++++ P YLILTLLRFS+
Sbjct: 711 GGETTPSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSY 770
Query: 814 DLRTMRRRKILDDVSIPLLLRLPLA-------------------------------GGRG 842
D + RRKILD+VS+PL+L LP+ G
Sbjct: 771 DQKYHVRRKILDNVSLPLVLELPVKRITSFSSLSESWSVDVDFTDLSENLAKKLKPSGTD 830
Query: 843 QA-------YDLCSVVVHSGVSSESGHYYCYARE-------------------------- 869
+A Y L SVVVHSG+SSESGHYY YAR
Sbjct: 831 EASCTKLVPYLLSSVVVHSGISSESGHYYSYARNITSTDSSYQMYHQSEALALASSQSHL 890
Query: 870 -GAARPAASLGT-ADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFY-RQR 926
G P+A + E +W+LFND+RV+F+SF+SV +TS FPKDTAYVL Y +Q
Sbjct: 891 LGRDSPSAVFEQDLENKEMSKEWFLFNDSRVTFTSFQSVQKITSRFPKDTAYVLLYKKQH 950
Query: 927 PREGPEAELGSSR--VRTEPTLHKDLMEAISKDNILYLQEQEKEARSRAAYISALPTSPH 984
G +S + +P L K+LM+AI+KDN LYLQEQE AR+RA ++ S
Sbjct: 951 STNGLSGNNPTSGLWINGDPPLQKELMDAITKDNKLYLQEQELNARARALQAASASCS-- 1008
Query: 985 WGRGFDEDKDEDEGSPGGCNPAGGNGG 1011
F + +D PG C P GG GG
Sbjct: 1009 ----FRPNGFDDNDPPGSCGPTGGGGG 1031
>gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens]
Length = 485
Score = 87.0 bits (214), Expect = 8e-17
Identities = 47/143 (32%), Positives = 76/143 (53%), Gaps = 18/143 (12%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
+G + + D ++ FL EKL +NRY+CE+C S Q+A + + L PC L L L+RF FD
Sbjct: 244 QGHKQLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDR 303
Query: 816 RTMRRRKILDDVSIPLLLRL-PLAGGRG--QAYDLCSVVVHSGVSSESGHYYCYAREGAA 872
+T ++K+ + +L + P +G Y+L +V++H GVS+ SGHY + ++
Sbjct: 304 QTGHKKKLNTYIGFSEILDMEPYVEHKGGSYVYELSAVLIHRGVSAYSGHYIAHVKD--- 360
Query: 873 RPAASLGTADRPEPENQWYLFND 895
+WY FND
Sbjct: 361 ------------PQSGEWYKFND 371
Score = 52.4 bits (124), Expect = 2e-06
Identities = 39/142 (27%), Positives = 58/142 (40%), Gaps = 24/142 (16%)
Query: 413 LGQDAWTSQKSELAGFY----PRLMAKSDTGKIGLINLGNTCYVNSILQALFMASDFRHC 468
+G+ W + E + F+ P + +GL NLG TCYVN+ LQ F+ + R
Sbjct: 58 IGEHIWLGEIDENS-FHNIDDPNCERRKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQA 116
Query: 469 VLRLTENNS----------------QPLMTKLQWLFGFLEHSQRPAISPENFLSASWTPW 512
+ S Q + LQ+LF L++S R I P F+ A
Sbjct: 117 LYLCPSTCSDYMLGDGIQEEKDYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKAL---G 173
Query: 513 FSPGTQQDCSEYLKYLLDRLHE 534
G QQD E+ K + L +
Sbjct: 174 LDTGQQQDAQEFSKLFMSLLED 195
>gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens]
Length = 1035
Score = 87.0 bits (214), Expect = 8e-17
Identities = 47/143 (32%), Positives = 76/143 (53%), Gaps = 18/143 (12%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
+G + + D ++ FL EKL +NRY+CE+C S Q+A + + L PC L L L+RF FD
Sbjct: 244 QGHKQLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDR 303
Query: 816 RTMRRRKILDDVSIPLLLRL-PLAGGRG--QAYDLCSVVVHSGVSSESGHYYCYAREGAA 872
+T ++K+ + +L + P +G Y+L +V++H GVS+ SGHY + ++
Sbjct: 304 QTGHKKKLNTYIGFSEILDMEPYVEHKGGSYVYELSAVLIHRGVSAYSGHYIAHVKD--- 360
Query: 873 RPAASLGTADRPEPENQWYLFND 895
+WY FND
Sbjct: 361 ------------PQSGEWYKFND 371
Score = 52.4 bits (124), Expect = 2e-06
Identities = 39/142 (27%), Positives = 58/142 (40%), Gaps = 24/142 (16%)
Query: 413 LGQDAWTSQKSELAGFY----PRLMAKSDTGKIGLINLGNTCYVNSILQALFMASDFRHC 468
+G+ W + E + F+ P + +GL NLG TCYVN+ LQ F+ + R
Sbjct: 58 IGEHIWLGEIDENS-FHNIDDPNCERRKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQA 116
Query: 469 VLRLTENNS----------------QPLMTKLQWLFGFLEHSQRPAISPENFLSASWTPW 512
+ S Q + LQ+LF L++S R I P F+ A
Sbjct: 117 LYLCPSTCSDYMLGDGIQEEKDYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKAL---G 173
Query: 513 FSPGTQQDCSEYLKYLLDRLHE 534
G QQD E+ K + L +
Sbjct: 174 LDTGQQQDAQEFSKLFMSLLED 195
>gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo
sapiens]
Length = 359
Score = 85.1 bits (209), Expect = 3e-16
Identities = 60/166 (36%), Positives = 86/166 (51%), Gaps = 10/166 (6%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL--RLTENNSQPLMTKLQWLFGFLEHSQRP-- 497
GL+N GNTCY NS+LQAL+ FR VL + + + L+T L LF + ++
Sbjct: 29 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVG 88
Query: 498 AISPENFLS--ASWTPWFSPGTQQDCSEYLKYLLDRLH---EEEKTGTRICQKLKQSSSP 552
I P+ F+S F QQD E+L YLL+ + +EEK + KLK + +
Sbjct: 89 VIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLK-NGNM 147
Query: 553 SPPEEPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSL 598
+ P E P T V ++F G + CL C VSS++E F DLS+
Sbjct: 148 NEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSV 193
Score = 73.2 bits (178), Expect = 1e-12
Identities = 54/180 (30%), Positives = 81/180 (45%), Gaps = 26/180 (14%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
E + S+ + F + E L +E +YYCE+C S Q+A+K + + + P L L L RF +
Sbjct: 196 EQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYME 255
Query: 816 RTMRRRKILDDVSIPLLLRL----PLAGGRGQAYDLCSVVVHSGVSSESGHYYCYAREGA 871
+ R K+ V PL LRL A + YDL +VVVH G GHY +
Sbjct: 256 QLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKS-- 313
Query: 872 ARPAASLGTADRPEPENQWYLFND---TRVSFSSFESVSNVTSFFPK--DTAYVLFYRQR 926
W LF+D ++ + E +TS K ++ Y+LFY+ R
Sbjct: 314 ---------------HGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSR 358
>gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo
sapiens]
Length = 366
Score = 85.1 bits (209), Expect = 3e-16
Identities = 60/166 (36%), Positives = 86/166 (51%), Gaps = 10/166 (6%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL--RLTENNSQPLMTKLQWLFGFLEHSQRP-- 497
GL+N GNTCY NS+LQAL+ FR VL + + + L+T L LF + ++
Sbjct: 36 GLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVG 95
Query: 498 AISPENFLS--ASWTPWFSPGTQQDCSEYLKYLLDRLH---EEEKTGTRICQKLKQSSSP 552
I P+ F+S F QQD E+L YLL+ + +EEK + KLK + +
Sbjct: 96 VIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLK-NGNM 154
Query: 553 SPPEEPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSL 598
+ P E P T V ++F G + CL C VSS++E F DLS+
Sbjct: 155 NEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSV 200
Score = 73.2 bits (178), Expect = 1e-12
Identities = 54/180 (30%), Positives = 81/180 (45%), Gaps = 26/180 (14%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
E + S+ + F + E L +E +YYCE+C S Q+A+K + + + P L L L RF +
Sbjct: 203 EQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYME 262
Query: 816 RTMRRRKILDDVSIPLLLRL----PLAGGRGQAYDLCSVVVHSGVSSESGHYYCYAREGA 871
+ R K+ V PL LRL A + YDL +VVVH G GHY +
Sbjct: 263 QLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKS-- 320
Query: 872 ARPAASLGTADRPEPENQWYLFND---TRVSFSSFESVSNVTSFFPK--DTAYVLFYRQR 926
W LF+D ++ + E +TS K ++ Y+LFY+ R
Sbjct: 321 ---------------HGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSR 365
>gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens]
Length = 370
Score = 75.9 bits (185), Expect = 2e-13
Identities = 57/171 (33%), Positives = 81/171 (47%), Gaps = 20/171 (11%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL--RLTENNSQPLMTKLQWLFGFLEHSQRP-- 497
GL+N GNTCY NS+LQAL+ FR VL + + L+T L LF + ++
Sbjct: 40 GLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKESLLTCLADLFHSIATQKKKVG 99
Query: 498 AISPENFLS--ASWTPWFSPGTQQDCSEYLKYLL----DRLHEEEKTGTRICQKLKQSSS 551
I P+ F++ F QQD E+L YLL D L EE K Q+ +
Sbjct: 100 VIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERK------QEKQNGRL 153
Query: 552 PS----PPEEPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSL 598
P+ P T V+++F G + CL C +SS++E F DLS+
Sbjct: 154 PNGNIDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSV 204
Score = 73.2 bits (178), Expect = 1e-12
Identities = 54/180 (30%), Positives = 81/180 (45%), Gaps = 26/180 (14%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
E + S+ + F + E L +E +YYCE C S Q+A K +++ + P L L L RF +
Sbjct: 207 EQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMD 266
Query: 816 RTMRRRKILDDVSIPLLLRLPLAGGRG----QAYDLCSVVVHSGVSSESGHYYCYAREGA 871
+ R K+ V PL LRL G + YDL +VVVH G GHY +
Sbjct: 267 QLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKS-- 324
Query: 872 ARPAASLGTADRPEPENQWYLFND---TRVSFSSFESVSNVTSFFPK--DTAYVLFYRQR 926
+ W LF+D ++ + E +TS K ++ Y+LFY+ R
Sbjct: 325 ---------------HDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSR 369
>gi|62243586 ubiquitin-specific protease 21 [Homo sapiens]
Length = 565
Score = 72.4 bits (176), Expect = 2e-12
Identities = 60/197 (30%), Positives = 85/197 (43%), Gaps = 33/197 (16%)
Query: 438 TGKIGLINLGNTCYVNSILQALFMASDFRHCVLRLT-------ENNSQPLMTKLQWLFGF 490
+G +GL NLGNTC++N++LQ L R LR +Q L + G
Sbjct: 209 SGHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGGGRAQELTEAFADVIGA 268
Query: 491 LEHSQR-PAISPENFLSA--SWTPWFSPGTQQDCSEYLKYLLDRLH-EEEKTGTRICQKL 546
L H A++P F + + P FS +QQD E+LK L++RLH E + G R L
Sbjct: 269 LWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPIL 328
Query: 547 KQSSSPSPP-------EEPPAP---------------SSTSVEKMFGGKIVTRICCLCCL 584
PSPP EEP + + +F G++ + + C C
Sbjct: 329 ANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACG 388
Query: 585 NVSSREEAFTDLSLAFP 601
S+ E F DLSL P
Sbjct: 389 YRSTTFEVFCDLSLPIP 405
Score = 51.2 bits (121), Expect = 5e-06
Identities = 45/170 (26%), Positives = 71/170 (41%), Gaps = 27/170 (15%)
Query: 757 GSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDLR 816
G S+ D N F E+L +EN C+ C + K + + + P L+L L RFS
Sbjct: 412 GKVSLRDCFNLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRG 471
Query: 817 TMRRRKILDDVSIPLLLRLPLAGGR--GQAYDLCSVVVHSGVSSESGHYYCYAREGAARP 874
++++ + D + L A + Y L ++ HSG S GHY R
Sbjct: 472 SIKKSSVGVDFPLQRLSLGDFASDKAGSPVYQLYALCNHSG-SVHYGHYTALCR------ 524
Query: 875 AASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYR 924
+ W+++ND+RVS S V++ YVLFY+
Sbjct: 525 -----------CQTGWHVYNDSRVSPVSENQVAS-------SEGYVLFYQ 556
>gi|74027267 ubiquitin-specific protease 21 [Homo sapiens]
Length = 565
Score = 72.4 bits (176), Expect = 2e-12
Identities = 60/197 (30%), Positives = 85/197 (43%), Gaps = 33/197 (16%)
Query: 438 TGKIGLINLGNTCYVNSILQALFMASDFRHCVLRLT-------ENNSQPLMTKLQWLFGF 490
+G +GL NLGNTC++N++LQ L R LR +Q L + G
Sbjct: 209 SGHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGGGRAQELTEAFADVIGA 268
Query: 491 LEHSQR-PAISPENFLSA--SWTPWFSPGTQQDCSEYLKYLLDRLH-EEEKTGTRICQKL 546
L H A++P F + + P FS +QQD E+LK L++RLH E + G R L
Sbjct: 269 LWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPIL 328
Query: 547 KQSSSPSPP-------EEPPAP---------------SSTSVEKMFGGKIVTRICCLCCL 584
PSPP EEP + + +F G++ + + C C
Sbjct: 329 ANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACG 388
Query: 585 NVSSREEAFTDLSLAFP 601
S+ E F DLSL P
Sbjct: 389 YRSTTFEVFCDLSLPIP 405
Score = 51.2 bits (121), Expect = 5e-06
Identities = 45/170 (26%), Positives = 71/170 (41%), Gaps = 27/170 (15%)
Query: 757 GSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDLR 816
G S+ D N F E+L +EN C+ C + K + + + P L+L L RFS
Sbjct: 412 GKVSLRDCFNLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRG 471
Query: 817 TMRRRKILDDVSIPLLLRLPLAGGR--GQAYDLCSVVVHSGVSSESGHYYCYAREGAARP 874
++++ + D + L A + Y L ++ HSG S GHY R
Sbjct: 472 SIKKSSVGVDFPLQRLSLGDFASDKAGSPVYQLYALCNHSG-SVHYGHYTALCR------ 524
Query: 875 AASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYR 924
+ W+++ND+RVS S V++ YVLFY+
Sbjct: 525 -----------CQTGWHVYNDSRVSPVSENQVAS-------SEGYVLFYQ 556
>gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]
Length = 520
Score = 71.6 bits (174), Expect = 3e-12
Identities = 59/195 (30%), Positives = 88/195 (45%), Gaps = 26/195 (13%)
Query: 442 GLINLGNTCYVNSILQALFMASDF--------------------RHCVLRLTENNSQPLM 481
GL NLGNTC++N+ILQ+L F R R +N+ L+
Sbjct: 160 GLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLV 219
Query: 482 TKLQWLFGFLEHSQRPAISPENFLSASWT--PWFSPGTQQDCSEYLKYLLDRLHEEEKTG 539
+ + L + A SPE+ W P F QQD E+++YLLD LH E + G
Sbjct: 220 EEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGG 279
Query: 540 TRICQK---LKQSSSPSPPEEPPAP-SSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTD 595
+ L+++S+ S + +ST V +FGG + + CL C S + + F D
Sbjct: 280 FNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLD 339
Query: 596 LSLAFPPPERCRRRR 610
LSL P R +R +
Sbjct: 340 LSLDIPSQFRSKRSK 354
Score = 62.0 bits (149), Expect = 3e-09
Identities = 55/189 (29%), Positives = 77/189 (40%), Gaps = 39/189 (20%)
Query: 760 SVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDLRTMR 819
S+ D + F E+L Y C C Q + K + + P L L L RF +
Sbjct: 363 SLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWT--AYL 420
Query: 820 RRKILDDVSIPL--------LLRLPLAGGRGQAYDLCSVVVHSGVSSESGHYYCYAREGA 871
R K+ V PL LL +G YDL +VVVH G SGHY YA
Sbjct: 421 RNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATH-- 478
Query: 872 ARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQRPREGP 931
E +W+ FND+ V+ + E+V K AY+LFY +
Sbjct: 479 ---------------EGRWFHFNDSTVTLTDEETV-------VKAKAYILFYVEH----- 511
Query: 932 EAELGSSRV 940
+A+ GS ++
Sbjct: 512 QAKAGSDKL 520
>gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens]
Length = 1123
Score = 71.2 bits (173), Expect = 5e-12
Identities = 61/199 (30%), Positives = 87/199 (43%), Gaps = 36/199 (18%)
Query: 760 SVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDLRTMR 819
+++ + F+ + L+ EN Y C C A K + + L L+L RF+
Sbjct: 280 NIVRALELFVKADVLSGENAYMCAKCKKKVPASKRFTIHRTSNVLTLSLKRFA----NFS 335
Query: 820 RRKILDDVSIPLLLRL----PLAGGRGQAYDLCSVVVHSGVSSESGHYYCYAREGAARPA 875
KI DV P L + G Y L +V+VHSG S +GHYYCY +
Sbjct: 336 GGKITKDVGYPEFLNIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVK------- 388
Query: 876 ASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQRP--REGPE- 932
AS G QWY ND+ V S+ + V N AYVLFY + P ++ PE
Sbjct: 389 ASNG---------QWYQMNDSLVHSSNVKVVLN-------QQAYVLFYLRIPGSKKSPEG 432
Query: 933 --AELGSSRVRTEPTLHKD 949
+ GSS + P++ D
Sbjct: 433 LISRTGSSSLPGRPSVIPD 451
Score = 54.3 bits (129), Expect = 6e-07
Identities = 43/164 (26%), Positives = 75/164 (45%), Gaps = 20/164 (12%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL-----RLTENNSQPLMTKLQWLFGFLEHSQR 496
GL NLGNTC++N+ +Q L + +L R S ++ +Q +
Sbjct: 123 GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHARSCHQGSFCMLCVMQNHIVQAFANSG 182
Query: 497 PAISPENFLS--ASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSP 554
AI P +F+ F G Q+D E+L+Y +D + + G C KL + +
Sbjct: 183 NAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYTIDAMQKACLNG---CAKLDRQTQ--- 236
Query: 555 PEEPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSL 598
++T V ++FGG + +R+ C C +VS + + D++L
Sbjct: 237 -------ATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVAL 273
>gi|239742285 PREDICTED: hypothetical protein XP_002342486 [Homo
sapiens]
Length = 559
Score = 70.9 bits (172), Expect = 6e-12
Identities = 54/175 (30%), Positives = 77/175 (44%), Gaps = 31/175 (17%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
+ ++SV + + PE+L EN Y+C C A K + L LIL L RFS
Sbjct: 228 QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS--- 284
Query: 816 RTMRRRKILDDVSIPLLLRLPLAGGRGQA----YDLCSVVVHSGVSSESGHYYCYAREGA 871
+ KI +V P L + L + + Y L +V+VH+G S +GHY+ Y +
Sbjct: 285 -DVTGNKIDKNVQYPECLDMKLYMSQTNSGPLVYVLYAVLVHAGWSCHNGHYFSYVK--- 340
Query: 872 ARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQR 926
E QWY +D V+ SS SV + AYVLFY Q+
Sbjct: 341 -------------AQEGQWYKMDDAEVTASSITSVLS-------QQAYVLFYIQK 375
Score = 50.1 bits (118), Expect = 1e-05
Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 25/184 (13%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL-----RLTENNSQPLMTKLQWLFGFLEHSQR 496
GL N+GNTCYVN+ LQ L + +L + + ++ +Q H+
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 497 PAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSPPE 556
I P L+A F G Q+D E+L + +D +K++ P +
Sbjct: 141 HVIQPSQALAAG----FHRGKQEDAHEFLMFTVD--------------AMKKACLPGHKQ 182
Query: 557 -EPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPERCRRRRLGSVM 615
+ + +T + ++FGG ++I CL C +S + + D++L + ++ L ++
Sbjct: 183 VDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSV-QQALEQLV 241
Query: 616 RPTE 619
+P E
Sbjct: 242 KPEE 245
>gi|169217654 PREDICTED: similar to deubiquitinating enzyme DUB1
[Homo sapiens]
Length = 530
Score = 69.7 bits (169), Expect = 1e-11
Identities = 54/175 (30%), Positives = 76/175 (43%), Gaps = 31/175 (17%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
+ ++SV + + PE+L EN Y+C C A K + L LIL L RFS
Sbjct: 228 QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS--- 284
Query: 816 RTMRRRKILDDVSIPLLLRL-PLAGGRGQ---AYDLCSVVVHSGVSSESGHYYCYAREGA 871
+ KI +V P L + P + Y L +V+VH+G S +GHY+ Y +
Sbjct: 285 -DVTGNKIAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVK--- 340
Query: 872 ARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQR 926
E QWY +D V+ SS SV + AYVLFY Q+
Sbjct: 341 -------------AQEGQWYKMDDAEVTASSITSVLS-------QQAYVLFYIQK 375
Score = 50.4 bits (119), Expect = 8e-06
Identities = 45/183 (24%), Positives = 80/183 (43%), Gaps = 23/183 (12%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL-----RLTENNSQPLMTKLQWLFGFLEHSQR 496
GL N+GNTCYVN+ LQ L + +L + + ++ +Q H+
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 497 PAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSPPE 556
I P L+A F G Q+D E+L + +D + + G KQ+ S
Sbjct: 141 HVIQPSQALAAG----FHRGKQEDAHEFLMFTVDAMKKACLPGH------KQADHHS--- 187
Query: 557 EPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPERCRRRRLGSVMR 616
+T + ++FGG ++I CL C +S + + D++L + ++ L +++
Sbjct: 188 ----KDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSV-QQALEQLVK 242
Query: 617 PTE 619
P E
Sbjct: 243 PEE 245
>gi|239758075 PREDICTED: similar to deubiquitinating enzyme DUB1
[Homo sapiens]
Length = 530
Score = 69.7 bits (169), Expect = 1e-11
Identities = 54/175 (30%), Positives = 76/175 (43%), Gaps = 31/175 (17%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
+ ++SV + + PE+L EN Y+C C A K + L LIL L RFS
Sbjct: 228 QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS--- 284
Query: 816 RTMRRRKILDDVSIPLLLRL-PLAGGRGQ---AYDLCSVVVHSGVSSESGHYYCYAREGA 871
+ KI +V P L + P + Y L +V+VH+G S +GHY+ Y +
Sbjct: 285 -DVTGNKIAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVK--- 340
Query: 872 ARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQR 926
E QWY +D V+ SS SV + AYVLFY Q+
Sbjct: 341 -------------AQEGQWYKMDDAEVTASSITSVLS-------QQAYVLFYIQK 375
Score = 50.1 bits (118), Expect = 1e-05
Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 25/184 (13%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL-----RLTENNSQPLMTKLQWLFGFLEHSQR 496
GL N+GNTCYVN+ LQ L + +L + + ++ +Q H+
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 497 PAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSPPE 556
I P L+A F G Q+D E+L + +D +K++ P +
Sbjct: 141 HVIQPSQALAAG----FHRGKQEDAHEFLMFTVD--------------AMKKACLPGHKQ 182
Query: 557 -EPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPERCRRRRLGSVM 615
+ + +T + ++FGG ++I CL C +S + + D++L + ++ L ++
Sbjct: 183 VDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSV-QQALEQLV 241
Query: 616 RPTE 619
+P E
Sbjct: 242 KPEE 245
>gi|239742297 PREDICTED: hypothetical protein XP_002342480 [Homo
sapiens]
Length = 530
Score = 69.7 bits (169), Expect = 1e-11
Identities = 54/175 (30%), Positives = 76/175 (43%), Gaps = 31/175 (17%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
+ ++SV + + PE+L EN Y+C C A K + L LIL L RFS
Sbjct: 228 QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS--- 284
Query: 816 RTMRRRKILDDVSIPLLLRL-PLAGGRGQ---AYDLCSVVVHSGVSSESGHYYCYAREGA 871
+ KI +V P L + P + Y L +V+VH+G S +GHY+ Y +
Sbjct: 285 -DVTGNKIAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVK--- 340
Query: 872 ARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQR 926
E QWY +D V+ SS SV + AYVLFY Q+
Sbjct: 341 -------------AQEGQWYKMDDAEVTASSITSVLS-------QQAYVLFYIQK 375
Score = 50.1 bits (118), Expect = 1e-05
Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 25/184 (13%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL-----RLTENNSQPLMTKLQWLFGFLEHSQR 496
GL N+GNTCYVN+ LQ L + +L + + ++ +Q H+
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 497 PAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSPPE 556
I P L+A F G Q+D E+L + +D +K++ P +
Sbjct: 141 HVIQPSQALAAG----FHRGKQEDAHEFLMFTVD--------------AMKKACLPGHKQ 182
Query: 557 -EPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPERCRRRRLGSVM 615
+ + +T + ++FGG ++I CL C +S + + D++L + ++ L ++
Sbjct: 183 VDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSV-QQALEQLV 241
Query: 616 RPTE 619
+P E
Sbjct: 242 KPEE 245
>gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens]
Length = 1316
Score = 69.7 bits (169), Expect = 1e-11
Identities = 57/185 (30%), Positives = 79/185 (42%), Gaps = 31/185 (16%)
Query: 743 DAAIPSGERTCGSEGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPC 802
D P + T + ++SV + F+ PE+L EN Y C C + A K + +
Sbjct: 252 DTFDPYLDITLEIKAAQSVNKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSN 311
Query: 803 YLILTLLRFSFDLRTMRRRKILDDVSIPLLL----RLPLAGGRGQAYDLCSVVVHSGVSS 858
L L+L RF+ KI DV P L + G Y L +V+VH+G +
Sbjct: 312 VLTLSLKRFA----NFTGGKIAKDVKYPEYLDIRPYMSQPNGEPIVYVLYAVLVHTGFNC 367
Query: 859 ESGHYYCYAREGAARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTA 918
+GHY+CY + AS G WY ND+ VS S SV + A
Sbjct: 368 HAGHYFCYIK-------ASNGL---------WYQMNDSIVSTSDIRSVLS-------QQA 404
Query: 919 YVLFY 923
YVLFY
Sbjct: 405 YVLFY 409
Score = 46.2 bits (108), Expect = 2e-04
Identities = 39/165 (23%), Positives = 70/165 (42%), Gaps = 22/165 (13%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVLRLTENNSQPLMTKLQWLFGFLEHSQRPAISP 501
GL NLGNTC+ N+ LQ L + +L E++ + H + +P
Sbjct: 112 GLQNLGNTCFANAALQCLTYTPPLANYMLS-HEHSKTCHAEGFCMMCTMQAHITQALSNP 170
Query: 502 ENFLSASWT--------PWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPS 553
+ + + F G Q+D E+L+Y +D + + G+ + Q
Sbjct: 171 GDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHTQ----- 225
Query: 554 PPEEPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSL 598
++T V ++FGG + +R+ CL C VS + + D++L
Sbjct: 226 --------ATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITL 262
>gi|157785653 ubiquitin specific peptidase 17 [Homo sapiens]
Length = 530
Score = 69.7 bits (169), Expect = 1e-11
Identities = 54/175 (30%), Positives = 76/175 (43%), Gaps = 31/175 (17%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
+ ++SV + + PE+L EN Y+C C A K + L LIL L RFS
Sbjct: 228 QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS--- 284
Query: 816 RTMRRRKILDDVSIPLLLRL-PLAGGRGQ---AYDLCSVVVHSGVSSESGHYYCYAREGA 871
+ KI +V P L + P + Y L +V+VH+G S +GHY+ Y +
Sbjct: 285 -DVTGNKIAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVK--- 340
Query: 872 ARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQR 926
E QWY +D V+ SS SV + AYVLFY Q+
Sbjct: 341 -------------AQEGQWYKMDDAEVTASSITSVLS-------QQAYVLFYIQK 375
Score = 47.8 bits (112), Expect = 5e-05
Identities = 42/184 (22%), Positives = 81/184 (44%), Gaps = 25/184 (13%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL-----RLTENNSQPLMTKLQWLFGFLEHSQR 496
GL N+GNTCYVN+ L+ L + +L + + ++ +Q H+
Sbjct: 81 GLQNMGNTCYVNASLEWLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 497 PAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSPPE 556
I P L+A F G Q+D E+L + +D +K++ P +
Sbjct: 141 HVIQPSQALAAG----FHRGKQEDAHEFLMFTVD--------------AMKKACLPGHKQ 182
Query: 557 -EPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPERCRRRRLGSVM 615
+ + +T + ++FGG ++I CL C +S + + D++L + ++ L ++
Sbjct: 183 VDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSV-QQALEQLV 241
Query: 616 RPTE 619
+P E
Sbjct: 242 KPEE 245
>gi|113415490 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
sapiens]
Length = 530
Score = 69.3 bits (168), Expect = 2e-11
Identities = 55/177 (31%), Positives = 76/177 (42%), Gaps = 35/177 (19%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
+ ++SV + + PE+L EN Y+C C A K + L LIL L RFS
Sbjct: 228 QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS--- 284
Query: 816 RTMRRRKILDDVSIPLLLRL------PLAGGRGQAYDLCSVVVHSGVSSESGHYYCYARE 869
+ KI +V P L + P G Y L +V+VH+G S +GHY+ Y +
Sbjct: 285 -DVTGNKIAKNVQYPECLDMQPYMSQPNTG--PLVYVLYAVLVHAGWSCHNGHYFSYVK- 340
Query: 870 GAARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQR 926
E QWY +D V+ SS SV + AYVLFY Q+
Sbjct: 341 ---------------AQEGQWYKMDDAEVTASSITSVLS-------QQAYVLFYIQK 375
Score = 50.1 bits (118), Expect = 1e-05
Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 25/184 (13%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL-----RLTENNSQPLMTKLQWLFGFLEHSQR 496
GL N+GNTCYVN+ LQ L + +L + + ++ +Q H+
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 497 PAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSPPE 556
I P L+A F G Q+D E+L + +D +K++ P +
Sbjct: 141 HVIQPSQALAAG----FHRGKQEDAHEFLMFTVD--------------AMKKACLPGHKQ 182
Query: 557 -EPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPERCRRRRLGSVM 615
+ + +T + ++FGG ++I CL C +S + + D++L + ++ L ++
Sbjct: 183 VDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSV-QQALEQLV 241
Query: 616 RPTE 619
+P E
Sbjct: 242 KPEE 245
>gi|113415488 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
sapiens]
Length = 530
Score = 69.3 bits (168), Expect = 2e-11
Identities = 55/177 (31%), Positives = 76/177 (42%), Gaps = 35/177 (19%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
+ ++SV + + PE+L EN Y+C C A K + L LIL L RFS
Sbjct: 228 QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS--- 284
Query: 816 RTMRRRKILDDVSIPLLLRL------PLAGGRGQAYDLCSVVVHSGVSSESGHYYCYARE 869
+ KI +V P L + P G Y L +V+VH+G S +GHY+ Y +
Sbjct: 285 -DVTGNKIAKNVQYPECLDMQPYMSQPNTG--PLVYVLYAVLVHAGWSCHNGHYFSYVK- 340
Query: 870 GAARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQR 926
E QWY +D V+ SS SV + AYVLFY Q+
Sbjct: 341 ---------------AQEGQWYKMDDAEVTASSITSVLS-------QQAYVLFYIQK 375
Score = 50.1 bits (118), Expect = 1e-05
Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 25/184 (13%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL-----RLTENNSQPLMTKLQWLFGFLEHSQR 496
GL N+GNTCYVN+ LQ L + +L + + ++ +Q H+
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 497 PAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSPPE 556
I P L+A F G Q+D E+L + +D +K++ P +
Sbjct: 141 HVIQPSQALAAG----FHRGKQEDAHEFLMFTVD--------------AMKKACLPGHKQ 182
Query: 557 -EPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPERCRRRRLGSVM 615
+ + +T + ++FGG ++I CL C +S + + D++L + ++ L ++
Sbjct: 183 VDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSV-QQALEQLV 241
Query: 616 RPTE 619
+P E
Sbjct: 242 KPEE 245
>gi|113415486 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
sapiens]
Length = 530
Score = 69.3 bits (168), Expect = 2e-11
Identities = 55/177 (31%), Positives = 76/177 (42%), Gaps = 35/177 (19%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
+ ++SV + + PE+L EN Y+C C A K + L LIL L RFS
Sbjct: 228 QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS--- 284
Query: 816 RTMRRRKILDDVSIPLLLRL------PLAGGRGQAYDLCSVVVHSGVSSESGHYYCYARE 869
+ KI +V P L + P G Y L +V+VH+G S +GHY+ Y +
Sbjct: 285 -DVTGNKIAKNVQYPECLDMQPYMSQPNTG--PLVYVLYAVLVHAGWSCHNGHYFSYVK- 340
Query: 870 GAARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQR 926
E QWY +D V+ SS SV + AYVLFY Q+
Sbjct: 341 ---------------AQEGQWYKMDDAEVTASSITSVLS-------QQAYVLFYIQK 375
Score = 50.1 bits (118), Expect = 1e-05
Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 25/184 (13%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL-----RLTENNSQPLMTKLQWLFGFLEHSQR 496
GL N+GNTCYVN+ LQ L + +L + + ++ +Q H+
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 497 PAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSPPE 556
I P L+A F G Q+D E+L + +D +K++ P +
Sbjct: 141 HVIQPSQALAAG----FHRGKQEDAHEFLMFTVD--------------AMKKACLPGHKQ 182
Query: 557 -EPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPERCRRRRLGSVM 615
+ + +T + ++FGG ++I CL C +S + + D++L + ++ L ++
Sbjct: 183 VDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSV-QQALEQLV 241
Query: 616 RPTE 619
+P E
Sbjct: 242 KPEE 245
>gi|113415484 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
sapiens]
Length = 530
Score = 69.3 bits (168), Expect = 2e-11
Identities = 55/177 (31%), Positives = 76/177 (42%), Gaps = 35/177 (19%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
+ ++SV + + PE+L EN Y+C C A K + L LIL L RFS
Sbjct: 228 QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS--- 284
Query: 816 RTMRRRKILDDVSIPLLLRL------PLAGGRGQAYDLCSVVVHSGVSSESGHYYCYARE 869
+ KI +V P L + P G Y L +V+VH+G S +GHY+ Y +
Sbjct: 285 -DVTGNKIAKNVQYPECLDMQPYMSQPNTG--PLVYVLYAVLVHAGWSCHNGHYFSYVK- 340
Query: 870 GAARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQR 926
E QWY +D V+ SS SV + AYVLFY Q+
Sbjct: 341 ---------------AQEGQWYKMDDAEVTASSITSVLS-------QQAYVLFYIQK 375
Score = 50.1 bits (118), Expect = 1e-05
Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 25/184 (13%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL-----RLTENNSQPLMTKLQWLFGFLEHSQR 496
GL N+GNTCYVN+ LQ L + +L + + ++ +Q H+
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 497 PAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSPPE 556
I P L+A F G Q+D E+L + +D +K++ P +
Sbjct: 141 HVIQPSQALAAG----FHRGKQEDAHEFLMFTVD--------------AMKKACLPGHKQ 182
Query: 557 -EPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPERCRRRRLGSVM 615
+ + +T + ++FGG ++I CL C +S + + D++L + ++ L ++
Sbjct: 183 VDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSV-QQALEQLV 241
Query: 616 RPTE 619
+P E
Sbjct: 242 KPEE 245
>gi|113415480 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
sapiens]
Length = 530
Score = 69.3 bits (168), Expect = 2e-11
Identities = 55/177 (31%), Positives = 76/177 (42%), Gaps = 35/177 (19%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
+ ++SV + + PE+L EN Y+C C A K + L LIL L RFS
Sbjct: 228 QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS--- 284
Query: 816 RTMRRRKILDDVSIPLLLRL------PLAGGRGQAYDLCSVVVHSGVSSESGHYYCYARE 869
+ KI +V P L + P G Y L +V+VH+G S +GHY+ Y +
Sbjct: 285 -DVTGNKIAKNVQYPECLDMQPYMSQPNTG--PLVYVLYAVLVHAGWSCHNGHYFSYVK- 340
Query: 870 GAARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQR 926
E QWY +D V+ SS SV + AYVLFY Q+
Sbjct: 341 ---------------AQEGQWYKMDDAEVTASSITSVLS-------QQAYVLFYIQK 375
Score = 50.1 bits (118), Expect = 1e-05
Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 25/184 (13%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL-----RLTENNSQPLMTKLQWLFGFLEHSQR 496
GL N+GNTCYVN+ LQ L + +L + + ++ +Q H+
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 497 PAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSPPE 556
I P L+A F G Q+D E+L + +D +K++ P +
Sbjct: 141 HVIQPSQALAAG----FHRGKQEDAHEFLMFTVD--------------AMKKACLPGHKQ 182
Query: 557 -EPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPERCRRRRLGSVM 615
+ + +T + ++FGG ++I CL C +S + + D++L + ++ L ++
Sbjct: 183 VDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSV-QQALEQLV 241
Query: 616 RPTE 619
+P E
Sbjct: 242 KPEE 245
>gi|113415478 PREDICTED: similar to deubiquitinating enzyme 1 [Homo
sapiens]
Length = 530
Score = 69.3 bits (168), Expect = 2e-11
Identities = 55/177 (31%), Positives = 76/177 (42%), Gaps = 35/177 (19%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
+ ++SV + + PE+L EN Y+C C A K + L LIL L RFS
Sbjct: 228 QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS--- 284
Query: 816 RTMRRRKILDDVSIPLLLRL------PLAGGRGQAYDLCSVVVHSGVSSESGHYYCYARE 869
+ KI +V P L + P G Y L +V+VH+G S +GHY+ Y +
Sbjct: 285 -DVTGNKIAKNVQYPECLDMQPYMSQPNTG--PLVYVLYAVLVHAGWSCHNGHYFSYVK- 340
Query: 870 GAARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQR 926
E QWY +D V+ SS SV + AYVLFY Q+
Sbjct: 341 ---------------AQEGQWYKMDDAEVTASSITSVLS-------QQAYVLFYIQK 375
Score = 50.1 bits (118), Expect = 1e-05
Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 25/184 (13%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL-----RLTENNSQPLMTKLQWLFGFLEHSQR 496
GL N+GNTCYVN+ LQ L + +L + + ++ +Q H+
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 497 PAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSPPE 556
I P L+A F G Q+D E+L + +D +K++ P +
Sbjct: 141 HVIQPSQALAAG----FHRGKQEDAHEFLMFTVD--------------AMKKACLPGHKQ 182
Query: 557 -EPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPERCRRRRLGSVM 615
+ + +T + ++FGG ++I CL C +S + + D++L + ++ L ++
Sbjct: 183 VDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSV-QQALEQLV 241
Query: 616 RPTE 619
+P E
Sbjct: 242 KPEE 245
>gi|113415476 PREDICTED: similar to deubiquitinating enzyme 3 [Homo
sapiens]
Length = 530
Score = 69.3 bits (168), Expect = 2e-11
Identities = 55/177 (31%), Positives = 76/177 (42%), Gaps = 35/177 (19%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
+ ++SV + + PE+L EN Y+C C A K + L LIL L RFS
Sbjct: 228 QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS--- 284
Query: 816 RTMRRRKILDDVSIPLLLRL------PLAGGRGQAYDLCSVVVHSGVSSESGHYYCYARE 869
+ KI +V P L + P G Y L +V+VH+G S +GHY+ Y +
Sbjct: 285 -DVTGNKIAKNVQYPECLDMQPYMSQPNTG--PLVYVLYAVLVHAGWSCHNGHYFSYVK- 340
Query: 870 GAARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQR 926
E QWY +D V+ SS SV + AYVLFY Q+
Sbjct: 341 ---------------AQEGQWYKMDDAEVTASSITSVLS-------QQAYVLFYIQK 375
Score = 50.1 bits (118), Expect = 1e-05
Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 25/184 (13%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL-----RLTENNSQPLMTKLQWLFGFLEHSQR 496
GL N+GNTCYVN+ LQ L + +L + + ++ +Q H+
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 497 PAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSPPE 556
I P L+A F G Q+D E+L + +D +K++ P +
Sbjct: 141 HVIQPSQALAAG----FHRGKQEDAHEFLMFTVD--------------AMKKACLPGHKQ 182
Query: 557 -EPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPERCRRRRLGSVM 615
+ + +T + ++FGG ++I CL C +S + + D++L + ++ L ++
Sbjct: 183 VDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSV-QQALEQLV 241
Query: 616 RPTE 619
+P E
Sbjct: 242 KPEE 245
>gi|239742295 PREDICTED: hypothetical protein XP_002342479 [Homo
sapiens]
Length = 530
Score = 69.3 bits (168), Expect = 2e-11
Identities = 55/177 (31%), Positives = 77/177 (43%), Gaps = 35/177 (19%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
+ ++SV + + PE+L EN Y+C C A K++ L LIL L RFS
Sbjct: 228 QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFS--- 284
Query: 816 RTMRRRKILDDVSIPLLLRL------PLAGGRGQAYDLCSVVVHSGVSSESGHYYCYARE 869
+ KI +V P L + P G Y L +V+VH+G S +GHY+ Y +
Sbjct: 285 -DVTGNKIAKNVQYPECLDMQPYMSQPNTG--PLVYVLYAVLVHAGWSCHNGHYFSYVK- 340
Query: 870 GAARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQR 926
E QWY +D V+ SS SV + AYVLFY Q+
Sbjct: 341 ---------------AQEGQWYKMDDAEVTASSITSVLS-------QQAYVLFYIQK 375
Score = 50.1 bits (118), Expect = 1e-05
Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 25/184 (13%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL-----RLTENNSQPLMTKLQWLFGFLEHSQR 496
GL N+GNTCYVN+ LQ L + +L + + ++ +Q H+
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 497 PAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSPPE 556
I P L+A F G Q+D E+L + +D +K++ P +
Sbjct: 141 HVIQPSQALAAG----FHRGKQEDAHEFLMFTVD--------------AMKKACLPGHKQ 182
Query: 557 -EPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPERCRRRRLGSVM 615
+ + +T + ++FGG ++I CL C +S + + D++L + ++ L ++
Sbjct: 183 VDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSV-QQALEQLV 241
Query: 616 RPTE 619
+P E
Sbjct: 242 KPEE 245
>gi|239742293 PREDICTED: hypothetical protein XP_002342478 [Homo
sapiens]
Length = 530
Score = 69.3 bits (168), Expect = 2e-11
Identities = 55/177 (31%), Positives = 76/177 (42%), Gaps = 35/177 (19%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
+ ++SV + + PE+L EN Y+C C A K + L LIL L RFS
Sbjct: 228 QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS--- 284
Query: 816 RTMRRRKILDDVSIPLLLRL------PLAGGRGQAYDLCSVVVHSGVSSESGHYYCYARE 869
+ KI +V P L + P G Y L +V+VH+G S +GHY+ Y +
Sbjct: 285 -DVTGNKIAKNVQYPECLDMQPYMSQPNTG--PLVYVLYAVLVHAGWSCHNGHYFSYVK- 340
Query: 870 GAARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQR 926
E QWY +D V+ SS SV + AYVLFY Q+
Sbjct: 341 ---------------AQEGQWYKMDDAEVTASSITSVLS-------QQAYVLFYIQK 375
Score = 50.1 bits (118), Expect = 1e-05
Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 25/184 (13%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL-----RLTENNSQPLMTKLQWLFGFLEHSQR 496
GL N+GNTCYVN+ LQ L + +L + + ++ +Q H+
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 497 PAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSPPE 556
I P L+A F G Q+D E+L + +D +K++ P +
Sbjct: 141 HVIQPSQALAAG----FHRGKQEDAHEFLMFTVD--------------AMKKACLPGHKQ 182
Query: 557 -EPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPERCRRRRLGSVM 615
+ + +T + ++FGG ++I CL C +S + + D++L + ++ L ++
Sbjct: 183 VDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSV-QQALEQLV 241
Query: 616 RPTE 619
+P E
Sbjct: 242 KPEE 245
>gi|239742280 PREDICTED: hypothetical protein XP_002342473 [Homo
sapiens]
Length = 530
Score = 69.3 bits (168), Expect = 2e-11
Identities = 55/177 (31%), Positives = 77/177 (43%), Gaps = 35/177 (19%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
+ ++SV + + PE+L EN Y+C C A K++ L LIL L RFS
Sbjct: 228 QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFS--- 284
Query: 816 RTMRRRKILDDVSIPLLLRL------PLAGGRGQAYDLCSVVVHSGVSSESGHYYCYARE 869
+ KI +V P L + P G Y L +V+VH+G S +GHY+ Y +
Sbjct: 285 -DVTGNKIAKNVQYPECLDMQPYMSQPNTG--PLVYVLYAVLVHAGWSCHNGHYFSYVK- 340
Query: 870 GAARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQR 926
E QWY +D V+ SS SV + AYVLFY Q+
Sbjct: 341 ---------------AQEGQWYKMDDAEVTASSITSVLS-------QQAYVLFYIQK 375
Score = 50.1 bits (118), Expect = 1e-05
Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 25/184 (13%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL-----RLTENNSQPLMTKLQWLFGFLEHSQR 496
GL N+GNTCYVN+ LQ L + +L + + ++ +Q H+
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 497 PAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSPPE 556
I P L+A F G Q+D E+L + +D +K++ P +
Sbjct: 141 HVIQPSQALAAG----FHRGKQEDAHEFLMFTVD--------------AMKKACLPGHKQ 182
Query: 557 -EPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPERCRRRRLGSVM 615
+ + +T + ++FGG ++I CL C +S + + D++L + ++ L ++
Sbjct: 183 VDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSV-QQALEQLV 241
Query: 616 RPTE 619
+P E
Sbjct: 242 KPEE 245
>gi|239742291 PREDICTED: hypothetical protein XP_002342477 [Homo
sapiens]
Length = 530
Score = 68.9 bits (167), Expect = 2e-11
Identities = 53/175 (30%), Positives = 75/175 (42%), Gaps = 31/175 (17%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
+ ++SV + + PE+L EN Y+C C A K + L LIL L RFS
Sbjct: 228 QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS--- 284
Query: 816 RTMRRRKILDDVSIPLLLRLPLAGGRGQ----AYDLCSVVVHSGVSSESGHYYCYAREGA 871
+ KI +V P L + + Y L +V+VH+G S +GHY+ Y +
Sbjct: 285 -DVTGNKIAKNVQYPECLDMQPYMSQTNTGPLVYVLYAVLVHAGWSCHNGHYFSYVK--- 340
Query: 872 ARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQR 926
E QWY +D V+ SS SV + AYVLFY Q+
Sbjct: 341 -------------AQEGQWYKMDDAEVTASSITSVLS-------QQAYVLFYIQK 375
Score = 50.1 bits (118), Expect = 1e-05
Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 25/184 (13%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL-----RLTENNSQPLMTKLQWLFGFLEHSQR 496
GL N+GNTCYVN+ LQ L + +L + + ++ +Q H+
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 497 PAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSPPE 556
I P L+A F G Q+D E+L + +D +K++ P +
Sbjct: 141 HVIQPSQALAAG----FHRGKQEDAHEFLMFTVD--------------AMKKACLPGHKQ 182
Query: 557 -EPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPERCRRRRLGSVM 615
+ + +T + ++FGG ++I CL C +S + + D++L + ++ L ++
Sbjct: 183 VDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSV-QQALEQLV 241
Query: 616 RPTE 619
+P E
Sbjct: 242 KPEE 245
>gi|239742289 PREDICTED: hypothetical protein XP_002342476 [Homo
sapiens]
Length = 530
Score = 68.9 bits (167), Expect = 2e-11
Identities = 53/175 (30%), Positives = 75/175 (42%), Gaps = 31/175 (17%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
+ ++SV + + PE+L EN Y+C C A K + L LIL L RFS
Sbjct: 228 QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS--- 284
Query: 816 RTMRRRKILDDVSIPLLLRLPLAGGRGQ----AYDLCSVVVHSGVSSESGHYYCYAREGA 871
+ KI +V P L + + Y L +V+VH+G S +GHY+ Y +
Sbjct: 285 -DVTGNKIAKNVQYPECLDMQPYMSQTNTGPLVYVLYAVLVHAGWSCHNGHYFSYVK--- 340
Query: 872 ARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQR 926
E QWY +D V+ SS SV + AYVLFY Q+
Sbjct: 341 -------------AQEGQWYKMDDAEVTASSITSVLS-------QQAYVLFYIQK 375
Score = 50.1 bits (118), Expect = 1e-05
Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 25/184 (13%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL-----RLTENNSQPLMTKLQWLFGFLEHSQR 496
GL N+GNTCYVN+ LQ L + +L + + ++ +Q H+
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 497 PAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSPPE 556
I P L+A F G Q+D E+L + +D +K++ P +
Sbjct: 141 HVIQPSQALAAG----FHRGKQEDAHEFLMFTVD--------------AMKKACLPGHKQ 182
Query: 557 -EPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPERCRRRRLGSVM 615
+ + +T + ++FGG ++I CL C +S + + D++L + ++ L ++
Sbjct: 183 VDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSV-QQALEQLV 241
Query: 616 RPTE 619
+P E
Sbjct: 242 KPEE 245
>gi|239742278 PREDICTED: hypothetical protein XP_002342472 [Homo
sapiens]
Length = 530
Score = 68.9 bits (167), Expect = 2e-11
Identities = 53/175 (30%), Positives = 75/175 (42%), Gaps = 31/175 (17%)
Query: 756 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDL 815
+ ++SV + + PE+L EN Y+C C A K + L LIL L RFS
Sbjct: 228 QAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS--- 284
Query: 816 RTMRRRKILDDVSIPLLLRLPLAGGRGQ----AYDLCSVVVHSGVSSESGHYYCYAREGA 871
+ KI +V P L + + Y L +V+VH+G S +GHY+ Y +
Sbjct: 285 -DVTGNKIAKNVQYPECLDMQPYMSQTNTGPLVYVLYAVLVHAGWSCHNGHYFSYVK--- 340
Query: 872 ARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQR 926
E QWY +D V+ SS SV + AYVLFY Q+
Sbjct: 341 -------------AQEGQWYKMDDAEVTASSITSVLS-------QQAYVLFYIQK 375
Score = 50.1 bits (118), Expect = 1e-05
Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 25/184 (13%)
Query: 442 GLINLGNTCYVNSILQALFMASDFRHCVL-----RLTENNSQPLMTKLQWLFGFLEHSQR 496
GL N+GNTCYVN+ LQ L + +L + + ++ +Q H+
Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140
Query: 497 PAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSPPE 556
I P L+A F G Q+D E+L + +D +K++ P +
Sbjct: 141 HVIQPSQALAAG----FHRGKQEDAHEFLMFTVD--------------AMKKACLPGHKQ 182
Query: 557 -EPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPERCRRRRLGSVM 615
+ + +T + ++FGG ++I CL C +S + + D++L + ++ L ++
Sbjct: 183 VDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSV-QQALEQLV 241
Query: 616 RPTE 619
+P E
Sbjct: 242 KPEE 245
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,454,391
Number of Sequences: 37866
Number of extensions: 2438551
Number of successful extensions: 61615
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 901
Number of HSP's successfully gapped in prelim test: 669
Number of HSP's that attempted gapping in prelim test: 20253
Number of HSP's gapped (non-prelim): 18969
length of query: 1018
length of database: 18,247,518
effective HSP length: 112
effective length of query: 906
effective length of database: 14,006,526
effective search space: 12689912556
effective search space used: 12689912556
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.