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Search of human proteins with 148613880
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148613880 hypothetical protein LOC145773 [Homo sapiens]
(368 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148613880 hypothetical protein LOC145773 [Homo sapiens] 706 0.0
gi|115430110 hypothetical protein LOC153643 [Homo sapiens] 215 4e-56
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 67 3e-11
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 60 2e-09
gi|31982906 cingulin-like 1 [Homo sapiens] 60 4e-09
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 59 5e-09
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 57 2e-08
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 57 3e-08
gi|71061468 centromere protein E [Homo sapiens] 55 1e-07
gi|55770834 centromere protein F [Homo sapiens] 54 2e-07
gi|81295809 pericentrin [Homo sapiens] 52 6e-07
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 52 8e-07
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 51 2e-06
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 51 2e-06
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 51 2e-06
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 50 2e-06
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 50 2e-06
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 50 2e-06
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 50 2e-06
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 50 2e-06
gi|156104908 myosin heavy chain 6 [Homo sapiens] 50 3e-06
gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens] 50 3e-06
gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 50 4e-06
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 50 4e-06
gi|4506751 restin isoform a [Homo sapiens] 49 5e-06
gi|118498362 kinectin 1 isoform b [Homo sapiens] 49 7e-06
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 49 7e-06
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 49 7e-06
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 49 7e-06
gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens] 49 7e-06
>gi|148613880 hypothetical protein LOC145773 [Homo sapiens]
Length = 368
Score = 706 bits (1823), Expect = 0.0
Identities = 368/368 (100%), Positives = 368/368 (100%)
Query: 1 MENMHLRRVRTMPRHSQSLTMAPYSSVSLVEQLEDRILCHEKTTAALVEHAFRIKDDIVN 60
MENMHLRRVRTMPRHSQSLTMAPYSSVSLVEQLEDRILCHEKTTAALVEHAFRIKDDIVN
Sbjct: 1 MENMHLRRVRTMPRHSQSLTMAPYSSVSLVEQLEDRILCHEKTTAALVEHAFRIKDDIVN 60
Query: 61 SLQKMQNKGGGDRLARLFLEEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKT 120
SLQKMQNKGGGDRLARLFLEEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKT
Sbjct: 61 SLQKMQNKGGGDRLARLFLEEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKT 120
Query: 121 LEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEG 180
LEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEG
Sbjct: 121 LEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEG 180
Query: 181 QISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQ 240
QISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQ
Sbjct: 181 QISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQ 240
Query: 241 ERIEKELLQKIDQLSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEE 300
ERIEKELLQKIDQLSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEE
Sbjct: 241 ERIEKELLQKIDQLSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEE 300
Query: 301 EKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQLQKQIQL 360
EKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQLQKQIQL
Sbjct: 301 EKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQLQKQIQL 360
Query: 361 MQKPETPM 368
MQKPETPM
Sbjct: 361 MQKPETPM 368
>gi|115430110 hypothetical protein LOC153643 [Homo sapiens]
Length = 452
Score = 215 bits (548), Expect = 4e-56
Identities = 116/332 (34%), Positives = 203/332 (61%)
Query: 32 QLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNITAIVK 91
QLEDR+ +T A L+E AFRIK+DI LQ + LAR LE HI+ IT+IVK
Sbjct: 113 QLEDRLNNQARTIAFLLEQAFRIKEDISACLQGTHGFRKEESLARKLLESHIQTITSIVK 172
Query: 92 QLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHK 151
+L+++IE+L++QIRARD + GTN A+ + ++ L G+GDLRGRVARCD+SI +LS +
Sbjct: 173 KLSQNIEILEDQIRARDQAATGTNFAVHEINIKHLQGVGDLRGRVARCDSSIVKLSGDIH 232
Query: 152 TTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQL 211
+ + + K Q LET K+ + ++ QLL +++ + SEQ++ LKM D H++
Sbjct: 233 LFRQEHRQIEKAIQEFVPALETLSKNLDMKVMQLLGKIETASSEQTSNLKMVQGDYRHEM 292
Query: 212 QLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKENSGASERDMEK 271
LL+ KF L ++ + + W + + + K+ L I++ +++E SE ME+
Sbjct: 293 NLLEFKFHSLSSNLYEEVENNKKWTENQFLKYRKDHLGHINECLKVLQEKLEKSENKMEE 352
Query: 272 KLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEMKAEVNAGFTA 331
KL Q+S++++ QK+ + + E K+ ++ ++E Q+ ++ M+ E +GF +
Sbjct: 353 KLLQLSSKVENFINTQKQETQLSKVKHMENKLSKKMEQMEKQIWGELETMQNEYQSGFKS 412
Query: 332 VYESIGSLRQVLEAKMKLDRDQLQKQIQLMQK 363
+++S+ SL+Q+ + KM L++ ++QK ++ +Q+
Sbjct: 413 IHDSLSSLQQIQKTKMDLEKYKVQKDLKKLQR 444
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 67.0 bits (162), Expect = 3e-11
Identities = 64/347 (18%), Positives = 157/347 (45%), Gaps = 42/347 (12%)
Query: 47 LVEHAFRIKDDIVNSLQKMQNKGGGDRLA-RLFLEEHIRNITAIVKQLNRDIEVLQEQIR 105
L+ + + ++ L + +K + + R+ E ++ T ++ +++ + ++
Sbjct: 1354 LLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAA 1413
Query: 106 ARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQ 165
++ N++L+ + LGD + + ++ ARL + + + L ++ +
Sbjct: 1414 EAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHE 1473
Query: 166 AAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEEL 225
++ +L+ K+ + ++LL KLK ++ +S + L + K EE+
Sbjct: 1474 ESQALLDASQKEVQALSTELL------------KLKNTYEESIVGQETLRRENKNLQEEI 1521
Query: 226 SNQILSARSWLQQ--EQERIEKELLQKIDQLSLIVKENSGASER---------------- 267
SN R + E E+++K + ++ ++ + ++E GA ER
Sbjct: 1522 SNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAK 1581
Query: 268 -DMEKKLSQMSARLDKIEEGQKKTFDG-QRTRQEEEKMHGRITKLELQMNQNIKEMKAEV 325
++E+KLS+ ++ Q+ T D Q + E K +T+L+ +M +++ EM+ ++
Sbjct: 1582 AELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQL 1641
Query: 326 NAGFTAVYE---SIGSLR-QVLEAKMKLD-----RDQLQKQIQLMQK 363
+ V E S+G L+ Q+ + +M+LD L++Q+ + ++
Sbjct: 1642 SCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAER 1688
Score = 52.4 bits (124), Expect = 6e-07
Identities = 73/352 (20%), Positives = 151/352 (42%), Gaps = 48/352 (13%)
Query: 30 VEQLEDRILCHEKTTAALVEHAFRIKDDI------VNSLQKMQNKGGGDRLARLFLEEHI 83
V++L +R+ E+ + L +++D+ ++ L+ M K ++ E +
Sbjct: 931 VKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTT---EHKV 987
Query: 84 RNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRV-ARCDAS 142
+N+T V+ LN DI L + T L +E +LS L ++ + D
Sbjct: 988 KNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLH-MEEEKLSSLSKANLKLEQQVDEL 1046
Query: 143 IARLSAEHKTTYEGLQHLNKEQQAAKLILET--KIKDAEGQISQLLNRVDLSISEQSTKL 200
L E K + L+K + KL E+ ++ ++ +++ L + +L +S+ ++K+
Sbjct: 1047 EGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKV 1106
Query: 201 KMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQ------ERIEKELLQKIDQL 254
+ + L + + TV+EL QI + L+ E+ ER +L Q + L
Sbjct: 1107 ENE--------KGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADL 1158
Query: 255 SLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQM 314
+ ++E G+S +E I + Q+ F EE +H T
Sbjct: 1159 NERLEEVGGSSLAQLE------------ITKKQETKFQKLHRDMEEATLHFETT------ 1200
Query: 315 NQNIKEMKAEVNAGFTAVYESIGSLRQVLE---AKMKLDRDQLQKQIQLMQK 363
+ ++K+ A+ A E++ ++Q LE + ++L+ D L +++ M +
Sbjct: 1201 SASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTR 1252
Score = 36.6 bits (83), Expect = 0.037
Identities = 48/219 (21%), Positives = 93/219 (42%), Gaps = 22/219 (10%)
Query: 93 LNRDIEVLQEQIRARDN-ISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHK 151
L R+ + LQE+I N + GT + + ++++L + ++ +
Sbjct: 1510 LRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKL-----IEEEKTEVQVTLEETEGALE 1564
Query: 152 TTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQL 211
+ H E AK LE K+ + + +I + +I + L S S ++
Sbjct: 1565 RNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLD-SEAKSRIEV 1623
Query: 212 QLLDTKFKGTVEEL-------SNQILSARSWLQQEQERIEKELLQKID---QLSLIVKEN 261
L K + + E+ + Q+ A L Q Q +I K+L ++D QL+ +KE
Sbjct: 1624 TRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQI-KDLQMQLDDSTQLNSDLKEQ 1682
Query: 262 SGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEE 300
+ER + S + + L+ + Q++T G+R +EE
Sbjct: 1683 VAVAER----RNSLLQSELEDLRSLQEQTERGRRLSEEE 1717
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 60.5 bits (145), Expect = 2e-09
Identities = 80/362 (22%), Positives = 157/362 (43%), Gaps = 48/362 (13%)
Query: 29 LVEQLED-RILCH--EKTTAALVEHAFRIKD---DIVNSLQKMQNKGGGDRLARLFLEEH 82
L+ QLE+ R L H + A L +KD D+ NSL+K + + G LE
Sbjct: 2289 LLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGN-------LEGI 2341
Query: 83 IRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDAS 142
IR A ++ E L+ ++A + T+ + + M++ + L G+ +
Sbjct: 2342 IRQQEADIQNSKFSYEQLETDLQASREL---TSRLHEEINMKEQKIISLLSGKEEAIQVA 2398
Query: 143 IARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKM 202
IA L +H + L++L +++ ++LE + K A + +QL+ LK
Sbjct: 2399 IAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLME-----------TLKT 2447
Query: 203 SHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKENS 262
+++ Q LD+ F ++ L N QQ +ER +L+K + EN+
Sbjct: 2448 IKKENIQQKAQLDS-FVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENN 2506
Query: 263 GASER---------DMEKKLSQMSARLDKIEEGQKKTF---DGQRTR------QEEEKMH 304
E D+ + +++ A L + E + D Q+ + Q+ +++
Sbjct: 2507 KLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELE 2566
Query: 305 GRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQLQKQIQLMQKP 364
+ KLE ++ ++ +E ++ F A+ E L + +E+ +K+ QL +Q+ +Q+
Sbjct: 2567 NKYAKLEEKLKES-EEANEDLRRSFNALQEEKQDLSKEIES-LKVSISQLTRQVTALQEE 2624
Query: 365 ET 366
T
Sbjct: 2625 GT 2626
Score = 52.4 bits (124), Expect = 6e-07
Identities = 62/292 (21%), Positives = 146/292 (50%), Gaps = 23/292 (7%)
Query: 80 EEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLE-----MRQLSGLGDLRG 134
E + +N+ K+++ ++++E + DN S + + + +++LS + +LR
Sbjct: 705 EIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRA 764
Query: 135 RVARCDASIARLSAEHKTTYEG-LQHLN-KEQQAAKLILETKIKDAEGQISQ-LLNRVDL 191
+V + + ++A + + YE H N +Q L +E K KD + ++ Q L+ V L
Sbjct: 765 QVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQL 824
Query: 192 SISEQSTKLK-MSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQK 250
SEQST ++ + + N + ++L+ + V +S+++ L Q++ I K
Sbjct: 825 QFSEQSTLIRSLQSQLQNKESEVLEGAER--VRHISSKVEELSQALSQKELEI-----TK 877
Query: 251 IDQLSLIVKENSGASERDMEKKLSQMS----ARLDKIEEGQKKTFD-GQRTRQEEEKMHG 305
+DQL L K + ++ +E+K Q++ + +K+ + ++ F G + +E+++
Sbjct: 878 MDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLN- 936
Query: 306 RITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQLQKQ 357
+++ E + ++E EV++G Y+ + Q+ + +++ + D L+K+
Sbjct: 937 LLSRAEEAKKEQVEE-DNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKE 987
Score = 37.4 bits (85), Expect = 0.022
Identities = 62/366 (16%), Positives = 155/366 (42%), Gaps = 50/366 (13%)
Query: 2 ENMHLRRVRTMPRHSQSLTMAPYSSVSLVEQLEDRILCHEKTTAALVEHAFRIKDDIVNS 61
E M + +++ + + L + ++ + + E +++ + K++ +++
Sbjct: 142 EEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFIST 201
Query: 62 LQKMQNKGGGDRLA---------------RLFLEEHIRNITA--IVKQLNRDIEVLQEQI 104
LQ ++ ++ A RL +E ++ +T + ++ + + VLQ ++
Sbjct: 202 LQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKL 261
Query: 105 RARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQ 164
+ G + L+ + + R ++ + ++ AEH T ++ E+
Sbjct: 262 EEHEESLVGRAQVVDLLQQELTAA--EQRNQIL--SQQLQQMEAEHNTLRNTVE---TER 314
Query: 165 QAAKLILET-KIKDAEGQIS-QLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTV 222
+ +K++LE +++ AE ++S L + EQ + + + + L+ K K +
Sbjct: 315 EESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEM 374
Query: 223 EELSNQILSARSWLQQEQERIE------KELLQKIDQLSLIVKENSGASERDMEKKLSQM 276
EE ++ ILS + Q+ Q + +LLQ ++ ++ + E +++K ++
Sbjct: 375 EEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEI 434
Query: 277 SARLDKIEEGQKKTF----------DGQRTRQEEE--KMHGRITKLE------LQMNQNI 318
S L+++ Q +T +G + EE + R+ +LE L + +
Sbjct: 435 SQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIEL 494
Query: 319 KEMKAE 324
+E+KAE
Sbjct: 495 EELKAE 500
Score = 37.0 bits (84), Expect = 0.028
Identities = 62/291 (21%), Positives = 129/291 (44%), Gaps = 23/291 (7%)
Query: 63 QKMQNKGGGDRLARLFLEEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLE 122
+ MQ K R ++ LEE I I + + +++++ LQE + S T A T
Sbjct: 2139 KNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLD-----STVTQLAAFT-- 2191
Query: 123 MRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQI 182
+ +S L D R RV R ++ + E L ++ + +L+ +++ +
Sbjct: 2192 -KSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCS---VLKDQLRQMSIHM 2247
Query: 183 SQLLNRVDLSISEQSTKLKMSHRDSNHQLQ--LLDTKFKGTVEELSNQILSARSWL---Q 237
+L ++++S E ++ S + QLQ + DT +G +EL +Q+ R Q
Sbjct: 2248 EEL--KINISRLEHDKQIWESKAQTEVQLQQKVCDT-LQGENKELLSQLEETRHLYHSSQ 2304
Query: 238 QEQERIEKELLQKIDQLSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTR 297
E ++E EL DQL+ + S + E+ E+K + + + Q F ++
Sbjct: 2305 NELAKLESELKSLKDQLT----DLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLE 2360
Query: 298 QEEEKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMK 348
+ + ++L ++N +++ + ++ A+ +I LRQ + ++K
Sbjct: 2361 TDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIK 2411
Score = 35.4 bits (80), Expect = 0.082
Identities = 49/249 (19%), Positives = 105/249 (42%), Gaps = 26/249 (10%)
Query: 98 EVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGL 157
++ +E+++ ++ N K L +L RV+R + +A L E K
Sbjct: 971 QISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLS 1030
Query: 158 QHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRD------SNHQL 211
+ E + K E K + ++ + +ISE+ +L+ +D + Q
Sbjct: 1031 ETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQF 1090
Query: 212 QLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLS----LIVKEN------ 261
Q L + T+++ +NQI ++ + + Q I+K + D +VKE
Sbjct: 1091 QALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPP 1150
Query: 262 -SGASER---DMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQN 317
+G+SE ++E+K+ + +++ QKK + +R+ K + + E + +
Sbjct: 1151 CTGSSEHWKPELEEKILALEKEKEQL---QKKLQEALTSRKAILK---KAQEKERHLREE 1204
Query: 318 IKEMKAEVN 326
+K+ K + N
Sbjct: 1205 LKQQKDDYN 1213
Score = 33.9 bits (76), Expect = 0.24
Identities = 65/345 (18%), Positives = 135/345 (39%), Gaps = 62/345 (17%)
Query: 30 VEQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNITAI 89
++QL++RI E+ E + ++++ L ++ K G ++ L+E + + +
Sbjct: 1842 IDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKM----LQEEVTKMNLL 1897
Query: 90 VKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVAR-----CDASIA 144
+Q+ QE++ + LE R ++ L +L G + DA I
Sbjct: 1898 NQQI-------QEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIK 1950
Query: 145 R--LSAEHKTTYEGLQHLNKEQQAA---KLILETKI------------------------ 175
L +E K + + L +E+Q K +E++I
Sbjct: 1951 NELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKEL 2010
Query: 176 ----KDAEGQISQLLN-----RVDLSISEQSTK-LKMSHRDSNHQLQLLDTKFKGTVEEL 225
K+ + ++ QL + +S E++ K L+ +S L++ VE
Sbjct: 2011 QELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHR 2070
Query: 226 SN---QILSARSWLQQEQERIEKELLQKIDQLSLIVKENSGASERDMEKKLSQMSARLDK 282
++ S + L Q + L + +L ++ N + + M++K + RL++
Sbjct: 2071 KKAQAELASFKVLLDDTQSEAARVLADNL-KLKKELQSNKESVKSQMKQKDEDLERRLEQ 2129
Query: 283 IEEG---QKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEMKAE 324
EE +KK + EK+H T E+Q+ N K+ + +
Sbjct: 2130 AEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQ 2174
Score = 31.6 bits (70), Expect = 1.2
Identities = 54/284 (19%), Positives = 114/284 (40%), Gaps = 27/284 (9%)
Query: 97 IEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEG 156
+E+ +E R R + ++A + +E S A + R+ E++T +
Sbjct: 1690 LELEEENDRLRAEVHPAGDTAKECMETLLSSN--------ASMKEELERVKMEYETLSKK 1741
Query: 157 LQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDS----NHQLQ 212
Q L E+ + ++ EG +S+ N + T + S +
Sbjct: 1742 FQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQD 1801
Query: 213 LLDTKFKGTVEELSNQILSARSWLQQEQERIEK--ELLQKIDQLSLIV----------KE 260
L + T E SA + ++ ++ LQ+IDQL + KE
Sbjct: 1802 SLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKE 1861
Query: 261 NSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKE 320
S E + LSQ+S + +++ Q++ Q+ ++ R+TKL+ + +
Sbjct: 1862 FSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDD 1921
Query: 321 MKAEVNAGFTAVYESIGSLRQ-VLEAKMKLDRDQLQKQIQLMQK 363
++ + + SIG+ Q V +A++K + L+ +++ ++K
Sbjct: 1922 LEERLMNQLAELNGSIGNYCQDVTDAQIK--NELLESEMKNLKK 1963
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 59.7 bits (143), Expect = 4e-09
Identities = 71/351 (20%), Positives = 156/351 (44%), Gaps = 52/351 (14%)
Query: 31 EQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNITAIV 90
E+ ED + E+ AL +K+++ + Q+M D+L + + ++ + V
Sbjct: 747 EEQEDLLRKRERELTALKG---ALKEEVSSHDQEM------DKLKEQY-DAELQALRESV 796
Query: 91 KQLNRDIEVLQEQIRARDNISYGTNSALKTL--EMRQLSG---------------LGDLR 133
++ +++EVL + + GT +K L E +L G + DL+
Sbjct: 797 EEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLK 856
Query: 134 GRVARCDASIARLSAEHKTTYEGLQHLNKEQQ---AAKLILETKIKDAEGQISQLLNRVD 190
G A+ ++ + E + E L H KE++ +A+ LE +++ A+G +SQ
Sbjct: 857 GDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQ------ 910
Query: 191 LSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQK 250
+++ +L ++ + Q K + L N++ + R L + E+++KE+
Sbjct: 911 --TTQEQKQLSEKLKEESEQ--------KEQLRRLKNEMENERWHLGKTIEKLQKEMADI 960
Query: 251 IDQLSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKL 310
++ E + EK +++ +++E KT + +++R KM + +
Sbjct: 961 VEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKE---KTLEAEKSRLTAMKMQDEMRLM 1017
Query: 311 ELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAK--MKLDRDQLQKQIQ 359
E ++ ++ + + E + +++ L LEAK +K DR +L KQ++
Sbjct: 1018 EEEL-RDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQME 1067
Score = 41.6 bits (96), Expect = 0.001
Identities = 46/240 (19%), Positives = 105/240 (43%), Gaps = 37/240 (15%)
Query: 151 KTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLN---RVDLSISEQSTKLKMSHRDS 207
+ E L+ + E+ L+ +++++EG++ + L +V + + T+++
Sbjct: 648 RANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQL 707
Query: 208 NHQLQLLDTKFKGTVEE---LSNQILSARSWLQ------QEQERIEKELLQKIDQLSLIV 258
+ LD+ + E L ++L A+ LQ +EQE + ++ +++ L +
Sbjct: 708 SEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGAL 767
Query: 259 KENSGASERDMEKKLSQMSARL----DKIEEGQKKT------------------FDGQRT 296
KE + +++M+K Q A L + +EE K +
Sbjct: 768 KEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLL 827
Query: 297 RQEEEKMHGRITKLE---LQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQ 353
++E EK+ GR +LE Q+ + I+++K + + + G +RQ+ EA + +++
Sbjct: 828 QEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEE 887
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 59.3 bits (142), Expect = 5e-09
Identities = 78/381 (20%), Positives = 173/381 (45%), Gaps = 44/381 (11%)
Query: 2 ENMHLRRVRTMPRHSQSLTMAPYSSVSLVEQLEDRILCHEKTTAALVEHAFRIKD---DI 58
EN+ R T+ H + T+ +L EQL++R+ EK + ++ D
Sbjct: 292 ENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDA 351
Query: 59 VNSLQKMQNKGG---GDRLARL-----FLEEHIRNITAIVKQLNRDIEVLQEQIRARDNI 110
N +++++ G + ++ EE I + + +KQ+ E L+EQ +
Sbjct: 352 KNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERA 411
Query: 111 SY-----GTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQ 165
++ ++A KT E R+ L+ + +I + S E + + + Q L++ +Q
Sbjct: 412 AFEELEKALSTAQKTEEARR-----KLKAEMDEQIKTIEKTSEEERISLQ--QELSRVKQ 464
Query: 166 AAKLILETKIKDAEGQISQL--LNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVE 223
+++ K +E QI++L L+ +L+ EQ K+ R+ Q Q+ K +E
Sbjct: 465 E---VVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQM-----KVALE 516
Query: 224 ELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKENSGASERDMEKKLSQMSARLDKI 283
+ ++ L + QE+E+ E L++++ + S RD++++ R+ ++
Sbjct: 517 KSQSEYLK----ISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILEL 572
Query: 284 EEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVL 343
E +K+ + + ++ +H LE + N++ KE+ V T + ES+ + L
Sbjct: 573 ESSLEKSLQENKNQSKDLAVH-----LEAEKNKHNKEITVMVEKHKTEL-ESLKHQQDAL 626
Query: 344 -EAKMKLDRDQLQKQIQLMQK 363
K+++ + Q Q +++ +++
Sbjct: 627 WTEKLQVLKQQYQTEMEKLRE 647
Score = 58.9 bits (141), Expect = 7e-09
Identities = 69/349 (19%), Positives = 152/349 (43%), Gaps = 29/349 (8%)
Query: 41 EKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNITAIVKQLNRDIEVL 100
E+ + L + ++K ++ + + +N + ++EH +I K L I L
Sbjct: 704 EEELSVLKDQTDKMKQELEAKMDEQKNHH--QQQVDSIIKEHEVSIQRTEKALKDQINQL 761
Query: 101 QEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTT--YE--- 155
+ ++ RD + ++ LE G+L+ A+ D + SA H+ T YE
Sbjct: 762 ELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQL 821
Query: 156 -GLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVD---LSISEQSTKLKMSHRDSNHQL 211
LQ + + +++L ++ + E Q + +D + + + +L+ + + ++
Sbjct: 822 AQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKV 881
Query: 212 QLLDTKFKGTVE--------------ELSNQILSARSWLQQEQERIEKELLQKIDQLSLI 257
+ L ++ +E E N IL R ++E E + ++L K D + I
Sbjct: 882 KSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIH-I 940
Query: 258 VKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQ--RTRQEEEKMHGRITKLELQMN 315
+ E ++ EKK+ ++ + +++E KK Q + ++E E +++ E Q N
Sbjct: 941 LNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFN 1000
Query: 316 QNIKEMKAEVNAGFT-AVYESIGSLRQVLEAKMKLDRDQLQKQIQLMQK 363
+ EM +AG + AV + ++ +E+ ++ R +L I + +K
Sbjct: 1001 AKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEK 1049
Score = 50.8 bits (120), Expect = 2e-06
Identities = 63/302 (20%), Positives = 139/302 (46%), Gaps = 55/302 (18%)
Query: 57 DIVNSLQKMQNKGGGDRLARLFLEEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTNS 116
D++ L+K ++ +E+ ++++T + + D QEQ + I +
Sbjct: 865 DLMQQLEKQNSE----------MEQKVKSLTQVYESKLEDGNKEQEQTK---QILVEKEN 911
Query: 117 ALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQH-LNKEQQAAKLILET-- 173
+ + Q + L +++ + SI L+ E++T ++ + + K +Q AK + ET
Sbjct: 912 MILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLK 971
Query: 174 -KIKDAEGQISQLLNRVDLSISEQSTK-----LKMSHRDS---NHQLQLLDTKFKGTVEE 224
K+ D E ++ + L L +S++ + L+M+ +S + + L+T K +E
Sbjct: 972 KKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIES 1031
Query: 225 LS-------NQILSARSWLQQEQERIEKELLQKIDQLSLIVKENS-----------GASE 266
L+ N ++S W ++ ++ E+ LQ+I ++ L KE G +
Sbjct: 1032 LTEVHRRELNDVISI--WEKKLNQQAEE--LQEIHEIQLQEKEQEVAELKQKILLFGCEK 1087
Query: 267 RDMEKKLS-------QMSARLDKIEEGQK-KTFDGQRTRQEEEKMHGRITKLELQMNQNI 318
+M K+++ + L++++E K K+ Q+E K+ + KLE+ +N+++
Sbjct: 1088 EEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSL 1147
Query: 319 KE 320
KE
Sbjct: 1148 KE 1149
Score = 41.2 bits (95), Expect = 0.001
Identities = 54/274 (19%), Positives = 107/274 (39%), Gaps = 39/274 (14%)
Query: 94 NRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTT 153
N+ E+L+E + L +E + DL ++A + +L E
Sbjct: 1894 NKPTELLEENTEEKSKSHLVQPKLLSNMEAQH----NDLEFKLAGAEREKQKLGKEIVRL 1949
Query: 154 YEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQLQL 213
+ L+ L KE Q IL+ + E+ K+K D
Sbjct: 1950 QKDLRMLRKEHQQELEILKKEYDQ-----------------EREEKIKQEQED------- 1985
Query: 214 LDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKENSGASERDMEKKL 273
L+ K T+++L + + + +QE E KE + K ++ + E+ + KK+
Sbjct: 1986 LELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKI 2045
Query: 274 SQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIK----EMKAEVNAGF 329
++ L + + ++ D + EE+M ++ L+ Q+ + K +++ E N G
Sbjct: 2046 AEKDDDLKRTAKRYEEILDAR-----EEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGN 2100
Query: 330 TAVYESIGSLRQVLEAKMKLDRDQLQKQIQLMQK 363
V +I L+ L K L D K+ + ++
Sbjct: 2101 DNV--TIMELQTQLAQKTTLISDSKLKEQEFREQ 2132
Score = 40.8 bits (94), Expect = 0.002
Identities = 52/262 (19%), Positives = 108/262 (41%), Gaps = 39/262 (14%)
Query: 80 EEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARC 139
+E I + + Q N+ + L+ ++ + S L+T Q + + +L + +
Sbjct: 1478 DEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQK 1537
Query: 140 DASIARLSA-----------EHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNR 188
I L+ EHK + LQH + + + ++K+AE +I L N+
Sbjct: 1538 TIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEK----DNRVKEAEEKILTLENQ 1593
Query: 189 VDLSISEQSTKLK------MSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQER 242
V +E TK K +S + +L+ L+ + + E + ++ + +Q+
Sbjct: 1594 VYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLES---ESAAKLAELKRKAEQKIAA 1650
Query: 243 IEKELLQKIDQLSLIVKENSGASERDMEKKLSQ-------MSARLDKIEEGQKKTFDGQR 295
I+K+LL ++++ K+ + + ++ KL + + +L +E Q +T R
Sbjct: 1651 IKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPR 1710
Query: 296 --------TRQEEEKMHGRITK 309
T QEE G + K
Sbjct: 1711 SAKNVAAYTEQEEADSQGCVQK 1732
Score = 35.8 bits (81), Expect = 0.063
Identities = 70/360 (19%), Positives = 149/360 (41%), Gaps = 50/360 (13%)
Query: 15 HSQSLTMAPYSSVSLVEQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNKGGGD-- 72
+++ L MA +S + + + ++ +L E R +D+++ +K N+ +
Sbjct: 1000 NAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQ 1059
Query: 73 RLARLFLEEHIRNITAIVK----------QLNRDIEVLQEQIRARDNISYGTNSALKTLE 122
+ + L+E + + + + ++N++I L+E+ +D LK
Sbjct: 1060 EIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLK--- 1116
Query: 123 MRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQI 182
++ + + L + A + +L + + + L ++ K++ E + + ++
Sbjct: 1117 -QKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAE----EDKRKV 1171
Query: 183 SQLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQER 242
S+L +++ + E+ LK SH SN L+ +FK EEL+ Q+ + E
Sbjct: 1172 SELTSKLKTT-DEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEA 1230
Query: 243 IEKELLQ-KIDQLSLIVKENSGASERDMEKK---------LSQMSARLDKIEEGQKK--- 289
EL+ + + I+ S R + K +S++ A+L ++ E Q
Sbjct: 1231 KTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNI 1290
Query: 290 TFDGQRTRQEEEKMHGRITKLELQMNQNIKEMKAEVNAGFT---AVYESIGSLRQVLEAK 346
+F Q T Q EEK IK MKA++ + T A+ + G+ +Q K
Sbjct: 1291 SFQ-QATHQLEEK------------ENQIKSMKADIESLVTEKEALQKEGGNQQQAASEK 1337
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 57.4 bits (137), Expect = 2e-08
Identities = 67/333 (20%), Positives = 150/333 (45%), Gaps = 47/333 (14%)
Query: 31 EQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNITAIV 90
+Q +++ + TTA L E ++D+ L+++ +K ++ I+N+ A++
Sbjct: 488 QQHQEQQALQQSTTAKLRE----AQNDLEQVLRQIGDK-----------DQKIQNLEALL 532
Query: 91 KQLNRDIEVLQ---EQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLS 147
++ +I +L+ E + A+ G + L L+ + + L+ +V + + S
Sbjct: 533 QKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHT----LQEQVTQLTEKLKNQS 588
Query: 148 AEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDS 207
HK E L +EQ+A + ++ E +++L ++++ S E+ ++L + +
Sbjct: 589 ESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNES-KEKVSQLDIQIKAK 647
Query: 208 NHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKENSGASER 267
L + +L N + +A++ LQ +Q+ + K + ++DQ++ A +
Sbjct: 648 TELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNK-ITTQLDQVT--------AKLQ 698
Query: 268 DMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEMKAEVNA 327
D ++ SQ+ + L + +E Q+ E++ G+I KLE EV A
Sbjct: 699 DKQEHCSQLESHLKEYKEKYLS------LEQKTEELEGQIKKLEAD--------SLEVKA 744
Query: 328 GFTAVYESIGSLRQVLEAKMKLDRDQLQKQIQL 360
+ + RQ L ++L +L KQ+++
Sbjct: 745 SKEQALQDLQQQRQ-LNTDLELRATELSKQLEM 776
Score = 43.1 bits (100), Expect = 4e-04
Identities = 58/277 (20%), Positives = 124/277 (44%), Gaps = 38/277 (13%)
Query: 79 LEEHIRNITAIVKQLNRDIEVLQEQIRARD----NISYGTNSALKTLEM-RQLSGLGDLR 133
LE H++ L + E L+ QI+ + + AL+ L+ RQL+ +LR
Sbjct: 707 LESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELR 766
Query: 134 GR------------VARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQ 181
V+ + + S ++ + L +E+Q K ET ++ + Q
Sbjct: 767 ATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQ 826
Query: 182 ISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQE 241
+L NR+ +++E K+KM +L + K + ++S+ + +++S ++E +
Sbjct: 827 HEELNNRIQTTVTELQ-KVKMEKEALMTELSTV----KDKLSKVSDSLKNSKSEFEKENQ 881
Query: 242 R-------IEKELLQKIDQLSLIVKENSGASERDMEKKL---SQMSARLD-KIEEGQKKT 290
+ +EK + QL + EN+ +++++K L + S +L ++ Q++
Sbjct: 882 KGKAAILDLEKTCKELKHQLQ-VQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQL 940
Query: 291 FDGQRT----RQEEEKMHGRITKLELQMNQNIKEMKA 323
Q T +EE+++ G I +L+ Q K+++A
Sbjct: 941 IQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEA 977
Score = 42.7 bits (99), Expect = 5e-04
Identities = 71/338 (21%), Positives = 134/338 (39%), Gaps = 47/338 (13%)
Query: 55 KDDIVNSLQKMQNKGGGDRLARLFLEEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGT 114
K ++ N LQ+ + + A +E I + ++ + LQ R++ T
Sbjct: 989 KTELENKLQQQLTQAAQELAAE---KEKISVLQNNYEKSQETFKQLQSDFYGRESELLAT 1045
Query: 115 NSALKTLEMR-----------------QLSGLGDLRGRVARCDASIARLSAEHKTTYEGL 157
LK++E + Q + +L+ A + A+ + + + L
Sbjct: 1046 RQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKAL 1105
Query: 158 QHLNKEQQAA-KLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQL-QLLD 215
Q + KE+ K ++ K K AE I ++ R + I++ + +LK +S ++ L D
Sbjct: 1106 QDIQKEKSLKEKELVNEKSKLAE--IEEIKCRQEKEITKLNEELKSHKLESIKEITNLKD 1163
Query: 216 TK----------------FKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVK 259
K K VE+ + +++E+E ++KE ++K +L +K
Sbjct: 1164 AKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIK 1223
Query: 260 ENSGASERDME---KKLSQMSARLDKIEEGQKKTFDGQRTRQEEEK----MHGRITKLEL 312
E ++ E K Q++A + + +K+ QR E EK + G I LE
Sbjct: 1224 EKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEA 1283
Query: 313 QMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLD 350
+ N E +A + E +VLE + KLD
Sbjct: 1284 TVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLD 1321
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 57.0 bits (136), Expect = 3e-08
Identities = 61/278 (21%), Positives = 126/278 (45%), Gaps = 54/278 (19%)
Query: 92 QLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHK 151
+L RDI+ L+ + + + T + +K L +++GL ++ IA+L+ E K
Sbjct: 949 ELKRDIDDLELTLAKVEKEKHATENKVKNLT-EEMAGLDEI----------IAKLTKEKK 997
Query: 152 TTYEGLQHLNKEQQA----------AKLILETKIKDAEGQISQLLNRVDLSISEQSTKLK 201
E Q + QA AK+ LE ++ D EG + EQ K++
Sbjct: 998 ALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSL------------EQEKKVR 1045
Query: 202 MSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKEN 261
M L+ K +G ++ I+ + QQ ER++K+ + ++ L+ +++
Sbjct: 1046 MD-------LERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFE-LNALNARIEDE 1097
Query: 262 SGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEM 321
+ ++KKL ++ AR++++EE + +RT + ++ KL +++ ++E+
Sbjct: 1098 QALGSQ-LQKKLKELQARIEELEE----ELEAERTAR------AKVEKLRSDLSRELEEI 1146
Query: 322 --KAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQLQKQ 357
+ E G T+V + R+ KM+ D ++ Q
Sbjct: 1147 SERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQ 1184
Score = 44.3 bits (103), Expect = 2e-04
Identities = 61/301 (20%), Positives = 131/301 (43%), Gaps = 58/301 (19%)
Query: 100 LQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQH 159
LQE A + ++ +S KT Q + + DL V R +A+ A L + + + L
Sbjct: 1397 LQEAEEAVEAVNAKCSSLEKTKHRLQ-NEIEDLMVDVERSNAAAAALDKKQRNFDKILAE 1455
Query: 160 LNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFK 219
++ + ++ LE+ K+A S+S + KLK ++ +S L+ + K
Sbjct: 1456 WKQKYEESQSELESSQKEAR------------SLSTELFKLKNAYEESLEHLETFKRENK 1503
Query: 220 GTVEELSN--QILSARSWLQQEQERIEKELLQKIDQLSLIVKENSGASER---------- 267
EE+S+ + L + E E++ K+L + +L ++E + E
Sbjct: 1504 NLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQL 1563
Query: 268 -------DMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEE------------KMHGRIT 308
++E+KL++ +++ + + D +T + E KM G +
Sbjct: 1564 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLN 1623
Query: 309 KLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVL-EAKMKLD-----RDQLQKQIQLMQ 362
++E+Q++ + M AE + + SL+ +L + +++LD D L++ I +++
Sbjct: 1624 EMEIQLS-HANRMAAEAQ-------KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVE 1675
Query: 363 K 363
+
Sbjct: 1676 R 1676
Score = 28.9 bits (63), Expect = 7.7
Identities = 27/138 (19%), Positives = 59/138 (42%), Gaps = 36/138 (26%)
Query: 192 SISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEE---LSNQILSARSWLQQEQERIEKELL 248
S+ E+ T+LK + S + + L+ K ++E L Q+ + + L +ER ++ +
Sbjct: 851 SMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIK 910
Query: 249 QKIDQLSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRIT 308
KI +E K+ +M+ RL+ +EE+M+ +T
Sbjct: 911 NKIQ----------------LEAKVKEMNERLE-----------------DEEEMNAELT 937
Query: 309 KLELQMNQNIKEMKAEVN 326
+ ++ E+K +++
Sbjct: 938 AKKRKLEDECSELKRDID 955
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 54.7 bits (130), Expect = 1e-07
Identities = 72/326 (22%), Positives = 146/326 (44%), Gaps = 58/326 (17%)
Query: 73 RLARLFLEEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTL--EMRQLSGLG 130
R L L+E ++ + KQ+ DI++ Q Q+ A+ + L++ E+ +L+ L
Sbjct: 645 RSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLI 704
Query: 131 DLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQ-----AAKLILETKIKDAEGQISQL 185
D G+V + + L E K T + + LNKE + ++IL +++K ++ +L
Sbjct: 705 D--GKVPK--DLLCNLELEGKIT-DLQKELNKEVEENEALREEVILLSELKSLPSEVERL 759
Query: 186 LNRV-DLS-----ISEQSTKL--KMSHRDSNHQ------------LQLLDTKFKGTVEEL 225
+ D S I+ + KL ++ H++S Q L + +K T +E
Sbjct: 760 RKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEF 819
Query: 226 SN-------------QILSARSWLQQEQERIEKELLQKIDQLSLIVKENSGASERDMEKK 272
N +L + QE + KE QK D +K +++++K
Sbjct: 820 QNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKE-AQKFDSSLGALKTELSYKTQELQEK 878
Query: 273 LSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEMKAEVNAGFTAV 332
++ RL+++E+ +++ + T Q E+ IT+ ++ Q ++E+K +
Sbjct: 879 TREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITE---KLQQTLEEVK--------TL 927
Query: 333 YESIGSLRQVLEAKMKLDRDQLQKQI 358
+ L+Q L+ ++++RDQL+ I
Sbjct: 928 TQEKDDLKQ-LQESLQIERDQLKSDI 952
Score = 46.6 bits (109), Expect = 4e-05
Identities = 72/358 (20%), Positives = 146/358 (40%), Gaps = 73/358 (20%)
Query: 29 LVEQLED-RILCHEKTTAALVEHAFRIKDD---------IVNSLQKMQNKGGGDRLARLF 78
L E LE+ R + E+ VE +++ D I L+K + ++ +
Sbjct: 1674 LHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEEL----KIVHMH 1729
Query: 79 LEEH---IRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGR 135
L+EH I + IV + +I +Q+ + +N ALK +++ L
Sbjct: 1730 LKEHQETIDKLRGIVSEKTNEISNMQKDLEH-------SNDALKAQDLKIQEELRIAHMH 1782
Query: 136 VARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLL------NRV 189
+ +I +L + L ++ K+ + + L+ KI++ + QL+ N
Sbjct: 1783 LKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNET 1842
Query: 190 DLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQE--RIEKEL 247
+SE +LK +D + L L+ + ++L + +S +++ R+E+ L
Sbjct: 1843 QKKVSEME-QLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETL 1901
Query: 248 LQKIDQLSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRI 307
+ DQL ++E RD+E + +AR+ + + K+T D K+ +I
Sbjct: 1902 KLERDQLKESLQETKA---RDLEIQQELKTARM--LSKEHKETVD---------KLREKI 1947
Query: 308 TKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQLQKQIQLMQKPE 365
++ +Q++ K++ +D+LQK+IQ +QK E
Sbjct: 1948 SEKTIQISDIQKDLDKS--------------------------KDELQKKIQELQKKE 1979
Score = 37.0 bits (84), Expect = 0.028
Identities = 62/323 (19%), Positives = 138/323 (42%), Gaps = 35/323 (10%)
Query: 53 RIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNITAIVKQLNRDIEVLQEQIRARDNISY 112
+++++ + +L +M L + + R +T + ++N+ + D +
Sbjct: 388 KVQNEKIENLTRMLVTSSSLTLQQELKAKRKRRVTWCLGKINK-----MKNSNYADQFNI 442
Query: 113 GTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLI-- 170
TN KT ++ + LR D S+ S T + L + + A KL+
Sbjct: 443 PTNITTKTHKL----SINLLR----EIDESVCSESDVFSNTLDTLSEI-EWNPATKLLNQ 493
Query: 171 --LETKIKDAEGQISQL-LNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVE-ELS 226
+E+++ L L+ L ++ +LK+ ++ + + L+ K K E +L
Sbjct: 494 ENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLI 553
Query: 227 NQILSARSWLQQEQ---ERIEKELLQKIDQL----SLIVKENSGASERDMEKKLSQMSAR 279
++I + ++ ++ + + +E EL K++ L I K + +E +S
Sbjct: 554 HEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYS 613
Query: 280 LDKIEEGQ--KKT-FDGQRTRQEEEKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESI 336
L+ IE+ + K+T FD + + ++ + L++ + +KE+ + + I
Sbjct: 614 LESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATT----YKQMENDI 669
Query: 337 GSLRQVLEAKMKLDRDQLQKQIQ 359
+ LEAK K+ D L+K++Q
Sbjct: 670 QLYQSQLEAKKKMQVD-LEKELQ 691
Score = 36.6 bits (83), Expect = 0.037
Identities = 40/217 (18%), Positives = 102/217 (47%), Gaps = 18/217 (8%)
Query: 140 DASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTK 199
D+++ R+ E + LQ + E ++ K KD ++ ++L + E +
Sbjct: 1413 DSALLRIEIEMLGLSKRLQESHDEMKSV-----AKEKDDLQRLQEVLQSESDQLKENIKE 1467
Query: 200 LKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVK 259
+ H ++ +L++ K EE N++ S + E I+K+L D+L ++
Sbjct: 1468 IVAKHLETEEELKVAHCCLKEQ-EETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQ 1526
Query: 260 ENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIK 319
E E+ K++S++ +++++++ ++ R+ ++ I L++ ++
Sbjct: 1527 EIYEKEEQFNIKQISEVQEKVNELKQFKEH-------RKAKDSALQSIESKMLELTNRLQ 1579
Query: 320 EMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQLQK 356
E + E+ + + +++V EA ++++RDQL++
Sbjct: 1580 ESQEEIQ----IMIKEKEEMKRVQEA-LQIERDQLKE 1611
Score = 33.5 bits (75), Expect = 0.31
Identities = 54/286 (18%), Positives = 119/286 (41%), Gaps = 46/286 (16%)
Query: 41 EKTTAALVEHAFRIKDDIVN---SLQKMQNKGGGDRLARLFLEEHIRNITAIVKQLNRDI 97
E+ ++E R+ +IVN QK + G + + + ++ T V++ ++
Sbjct: 830 EQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEM 889
Query: 98 EVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGL 157
E L+EQ+ RD S L+T+E + ++ + + T E +
Sbjct: 890 EQLKEQLENRD-------STLQTVEREK------------------TLITEKLQQTLEEV 924
Query: 158 QHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDTK 217
+ L +E+ K + E+ + + S + + V+++I Q HQ + ++T
Sbjct: 925 KTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQ-ETINTL 983
Query: 218 FKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKENSGASERDMEKKLSQ-- 275
EE+S + +++ + E QK+ + ++D+E K +Q
Sbjct: 984 KSKISEEVSRNL-----HMEENTGETKDEFQQKMVGID---------KKQDLEAKNTQTL 1029
Query: 276 -MSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKE 320
+ ++I E Q+K F + + E ++M + + Q+ ++KE
Sbjct: 1030 TADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKE 1075
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 54.3 bits (129), Expect = 2e-07
Identities = 82/399 (20%), Positives = 171/399 (42%), Gaps = 56/399 (14%)
Query: 5 HLRRVRTMPRHSQSLTMAPY-SSVSLVEQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQ 63
+L R M +Q L + +S + VE L+ +I ++ ++ + N +
Sbjct: 2158 NLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTK 2217
Query: 64 KMQNKGGG----DRLARLF---LEEHIRNITAIVKQLNRDIEVLQEQIRARDNISY---G 113
++Q K G D+L F LEE + I ++ +E+LQ Q++ + G
Sbjct: 2218 QIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCG 2277
Query: 114 TNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILET 173
+K E + + + ARL A+ K LQ L + + A L+
Sbjct: 2278 DQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLL--- 2334
Query: 174 KIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSN---QIL 230
+G++ L ++++ + Q + +S +++ L K +G + L ++
Sbjct: 2335 -----KGRVENLERELEIARTNQE-HAALEAENSKGEVETLKAKIEGMTQSLRGLELDVV 2388
Query: 231 SARSW-------LQQEQERIEK---------ELLQKIDQLSLIVKENSGASERDMEKKLS 274
+ RS LQ+EQERI + +LQ+ +Q + +KE S + ++ +L
Sbjct: 2389 TIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLK 2448
Query: 275 QMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYE 334
+++ R+ + Q + + +E+ + ++ LEL+ Q ++ + E + +
Sbjct: 2449 ELNERVAALHNDQ------EACKAKEQNLSSQVECLELEKAQLLQGLD-EAKNNYIVLQS 2501
Query: 335 SI-GSLRQVLEAKMKLD---------RDQLQKQIQLMQK 363
S+ G +++V + K KL+ ++Q+Q Q QL+ K
Sbjct: 2502 SVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSK 2540
Score = 40.4 bits (93), Expect = 0.003
Identities = 71/374 (18%), Positives = 147/374 (39%), Gaps = 47/374 (12%)
Query: 23 PYSSVSLVEQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEH 82
P ++ +++LE ++ +K + F++ D + +LQK + K ++ L+
Sbjct: 13 PTRALQKIQELEGQL---DKLKKEKQQRQFQL-DSLEAALQKQKQKVENEKTEGTNLKRE 68
Query: 83 IRNITAIVKQLNRDIEVLQEQIRARD---NISYGT-NSALKTLEM------RQLSGLGDL 132
+ + I + L + + + +++ ++ N G NS K +E R S L
Sbjct: 69 NQRLMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERS 128
Query: 133 RGRVARCDASIARLSAEHK--TT-------YEGLQHLNKEQQAAKLILETKIKDAEGQIS 183
+ D S+ + K TT Y G ++ + +++ K + E K +AE +
Sbjct: 129 QQAAQSADVSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEERKRLEAEVKAL 188
Query: 184 QL-----------LNRVDLSISEQSTKL-------KMSHRDSNHQLQLLDTKFKGTVEEL 225
Q +N D++ + S+ + SH SN Q + F +
Sbjct: 189 QAKKASQTLPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRDFSASYFSG 248
Query: 226 SNQILSARSWLQQEQERIEKELLQKIDQLSLIVKENSGASERDMEKKLSQMSARLDKIEE 285
++ +RS LQ + L+ + A +++ K++++ RL +
Sbjct: 249 EQEVTPSRSTLQIGKRDANSSFFDNSSSPHLL--DQLKAQNQELRNKINELELRL----Q 302
Query: 286 GQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEA 345
G +K GQ + +E ++ K+EL + + + TA Y+ + LE
Sbjct: 303 GHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQ 362
Query: 346 KMKLDRDQLQKQIQ 359
K+K + L Q Q
Sbjct: 363 KLKKLTEDLSCQRQ 376
Score = 37.0 bits (84), Expect = 0.028
Identities = 53/243 (21%), Positives = 106/243 (43%), Gaps = 31/243 (12%)
Query: 143 IARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVD-LSISEQSTKLK 201
+ L+ E + + LQ N Q +L++ K+ E ++ L ++D +S E+ K+
Sbjct: 2558 LRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELE--LTKMDKMSFVEKVNKMT 2615
Query: 202 MSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKEN 261
+ ++ + K EELS + ++ L E + + +E+ DQL + EN
Sbjct: 2616 AKETELQREMHEMAQKTAELQEELSGE----KNRLAGELQLLLEEIKSSKDQLKELTLEN 2671
Query: 262 SGASERDMEKKLSQM-SARLDKIEEGQKKTFDGQRTRQEEEKMHGRIT-------KLELQ 313
S +++K L M +++K + +++ + Q E EK H + ++E+Q
Sbjct: 2672 S-----ELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQ 2726
Query: 314 --------MNQNIKEMKAEVNAGFTAVYESIGSLR---QVLEAKMKLDRDQLQKQIQLMQ 362
+ + K E++ ++ E SL+ Q+LE K D L+ QL +
Sbjct: 2727 TYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKK 2786
Query: 363 KPE 365
+ E
Sbjct: 2787 ENE 2789
Score = 35.0 bits (79), Expect = 0.11
Identities = 71/307 (23%), Positives = 130/307 (42%), Gaps = 51/307 (16%)
Query: 88 AIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLS 147
+ V + ++ I LQE A N+ T SAL+ E ++L L D +V A I L
Sbjct: 876 SFVAETSQRISKLQEDTSAHQNVVAETLSALENKE-KELQLLND---KVETEQAEIQELK 931
Query: 148 AEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDL-SISEQSTKLKMSHRD 206
+ + L KE Q L + K+ IS LN+ ++ +++++ LK +
Sbjct: 932 KSNHLLEDSL----KELQLLSETLSLEKKEMSSIIS--LNKREIEELTQENGTLKEINAS 985
Query: 207 SNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVK---ENSG 263
N + L K E +N I E+E+ EL + Q LI+ E +G
Sbjct: 986 LNQEKMNLIQK----SESFANYI--------DEREKSISELSDQYKQEKLILLQRCEETG 1033
Query: 264 ASERDMEKKLSQMSARLDKIE----------EGQKKTFDGQRTRQEEEKMHGR-ITKLEL 312
+ D+ +K + K+E E +K ++ ++ K H +TKL
Sbjct: 1034 NAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNEL--EQLKEAFAKEHQEFLTKLAF 1091
Query: 313 --QMNQNI--------KEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQLQKQI-QLM 361
+ NQN+ + +++E+ G L+Q + +K +++++QK++ L+
Sbjct: 1092 AEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEI-MTLKEEQNKMQKEVNDLL 1150
Query: 362 QKPETPM 368
Q+ E M
Sbjct: 1151 QENEQLM 1157
Score = 31.6 bits (70), Expect = 1.2
Identities = 50/263 (19%), Positives = 104/263 (39%), Gaps = 33/263 (12%)
Query: 129 LGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKE-------QQAAKLILETKIKDAEGQ 181
L R + R A + S ++ + L+ L ++ ++A+ LE KIK+ E +
Sbjct: 336 LNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKE 395
Query: 182 ISQLLNRVDLS--------------ISEQSTKLKMSHRDSNHQLQLLDT---KFKGTVEE 224
+ L+R S ++++ + K H +L L + + + +EE
Sbjct: 396 FQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEE 455
Query: 225 LSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKENSGASERDMEK--KLSQMSARLDK 282
++ A Q Q + E EL + ++++ KEN+ +K ++ + A L
Sbjct: 456 FKQKLCRAEQAFQASQIK-ENELRRSMEEMK---KENNLLKSHSEQKAREVCHLEAELKN 511
Query: 283 IEE--GQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLR 340
I++ Q + F + + + + L+ ++NQ + E A E
Sbjct: 512 IKQCLNQSQNF-AEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCS 570
Query: 341 QVLEAKMKLDRDQLQKQIQLMQK 363
Q L K + +QL ++ +K
Sbjct: 571 QDLLKKREHHIEQLNDKLSKTEK 593
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 52.4 bits (124), Expect = 6e-07
Identities = 72/333 (21%), Positives = 144/333 (43%), Gaps = 34/333 (10%)
Query: 47 LVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNITAIVKQLNRDIEVLQEQIRA 106
L++ R K D N L K DR L EE I+ + + + + + LQE++
Sbjct: 1531 LLQQKLREKLDEFNELAIQ--KESADRQV-LMQEEEIKRLEEMNINIRKKVAQLQEEVEK 1587
Query: 107 RDNISYGTNSALKTLEMRQLSGL---GDLRGRV--ARCDASIARLSAEH-----KTTYEG 156
+ NI G + L+ +Q+S L L+ + RC + E + T
Sbjct: 1588 QKNIVKGLEQDKEVLKKQQMSSLLLASTLQSTLDAGRCPEPPSGSPPEGPEIQLEVTQRA 1647
Query: 157 LQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHR---DSNHQLQL 213
L E K LE D E + ++L+ ++L + Q+++ +S R + N L++
Sbjct: 1648 LLRRESEVLDLKEQLEKMKGDLESKNEEILH-LNLKLDMQNSQTAVSLRELEEENTSLKV 1706
Query: 214 LDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKENSGASERDMEKKL 273
+ T+ +EEL I + LQ+ Q+R++KE ++I+QL ++++ ++ +L
Sbjct: 1707 IYTR-SSEIEELKATIEN----LQENQKRLQKEKAEEIEQLHEVIEK--------LQHEL 1753
Query: 274 SQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKE----MKAEVNAGF 329
S M + ++ + Q + + + G+ + EL+ KE + A+
Sbjct: 1754 SLMGPVVHEVSDSQAGSLQSELLCSQAGGPRGQALQGELEAALEAKEALSRLLADQERRH 1813
Query: 330 TAVYESIGSLRQVLEAKMKLDRDQLQKQIQLMQ 362
+ E++ Q E +L +L++ + L +
Sbjct: 1814 SQALEALQQRLQGAEEAAELQLAELERNVALRE 1846
Score = 42.7 bits (99), Expect = 5e-04
Identities = 80/373 (21%), Positives = 166/373 (44%), Gaps = 53/373 (14%)
Query: 31 EQLEDRILCHEKTTAALVEHAFRIKD-DIVNSLQKMQNKGGGDRLARLFLEEHIRNITAI 89
EQL R LC + + K+ ++ +LQ+++++ G R + LEE
Sbjct: 2621 EQLS-RSLCEVQQEVLQLRSMLSSKENELKAALQELESEQGKGRALQSQLEEEQLRHLQR 2679
Query: 90 VKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIAR---- 145
Q + +E L+ + + S ALK + + + +LR +RC+A +A+
Sbjct: 2680 ESQSAKALEELRASLETQRAQSSRLCVALKHEQTAKDNLQKELRIEHSRCEALLAQERSQ 2739
Query: 146 -------LSAEHKTTY---EGLQH----------------LNKEQQAAKLILETKIKDAE 179
L+AE T E L+H ++++ QA +L+ K+K+ +
Sbjct: 2740 LSELQKDLAAEKSRTLELSEALRHERLLTEQLSQRTQEACVHQDTQAHHALLQ-KLKEEK 2798
Query: 180 GQISQL---LNRVD---LSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSAR 233
++ L L +V L +Q H ++ + + + K TVE L Q R
Sbjct: 2799 SRVVDLQAMLEKVQQQALHSQQQLEAEAQKHCEALRREKEVSATLKSTVEALHTQKRELR 2858
Query: 234 SWLQQEQER---IEKELLQKIDQLSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKT 290
L++E+E+ ++ EL Q +L +E A+ R E + S +A E+ +K
Sbjct: 2859 CSLEREREKPAWLQAELEQSHPRLK--EQEGRKAARRSAEARQSPAAA-----EQWRKWQ 2911
Query: 291 FDGQRTRQEEEKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLD 350
D ++ R+ E + + K++ Q+ Q +++++++ + ++ +GS R+ +
Sbjct: 2912 RDKEKLRELELQRQRDLHKIK-QLQQTVRDLESKDEVPGSRLH--LGSARRAAGSDADHL 2968
Query: 351 RDQLQKQIQLMQK 363
R+Q Q++++ M++
Sbjct: 2969 REQ-QRELEAMRQ 2980
Score = 32.7 bits (73), Expect = 0.53
Identities = 28/144 (19%), Positives = 67/144 (46%), Gaps = 10/144 (6%)
Query: 143 IARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKM 202
I L E++ Y LQH + + + + I+D + +++ + +L + ++ + +
Sbjct: 692 IELLKIENRNLYGKLQHETRLKDDLEKVKHNLIEDHQKELNNAKQKTEL-MKQEFQRKET 750
Query: 203 SHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQER-IEKELLQKIDQLSLIVKEN 261
+ +LQ + E+L+ +L R + E++ I K L++ + L ++
Sbjct: 751 DWKVMKEELQ------REAEEKLTLMLLELREKAESEKQTIINKFELREAEMRQL--QDQ 802
Query: 262 SGASERDMEKKLSQMSARLDKIEE 285
A D+E+ L++ RL ++E+
Sbjct: 803 QAAQILDLERSLTEQQGRLQQLEQ 826
Score = 30.8 bits (68), Expect = 2.0
Identities = 37/172 (21%), Positives = 80/172 (46%), Gaps = 22/172 (12%)
Query: 155 EGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLL 214
+G + E+ A L LET+ K L+ + + E+ LK+ +R+ +LQ
Sbjct: 657 DGDLEADTERAARVLGLETEHKVQ-------LSLLQTELKEEIELLKIENRNLYGKLQH- 708
Query: 215 DTKFKGTVEELSNQILSARSW----LQQEQERIEKELLQKIDQLSLIVKENSGASERDME 270
+T+ K +E++ + ++ +Q+ E +++E +K ++ +E +R+ E
Sbjct: 709 ETRLKDDLEKVKHNLIEDHQKELNNAKQKTELMKQEFQRKETDWKVMKEE----LQREAE 764
Query: 271 KKLSQMSARLDKIEEGQKKTFDGQ------RTRQEEEKMHGRITKLELQMNQ 316
+KL+ M L + E +K+T + RQ +++ +I LE + +
Sbjct: 765 EKLTLMLLELREKAESEKQTIINKFELREAEMRQLQDQQAAQILDLERSLTE 816
Score = 29.6 bits (65), Expect = 4.5
Identities = 31/153 (20%), Positives = 69/153 (45%), Gaps = 3/153 (1%)
Query: 214 LDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKENSGASERDMEKKL 273
L K + +E+L NQ + + E E+I ++ Q L + + A E+ E
Sbjct: 365 LSAKHQSEMEDLQNQFQKELAEQRAELEKIFQDKNQAERALRNLESHHQAAIEKLREDLQ 424
Query: 274 SQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEMKAEVNAGFTAVY 333
S+ L+ +E K++ + + E E + L+ Q + I+ + +++++ T+
Sbjct: 425 SEHGRCLEDLEFKFKES--EKEKQLELENLQASYEDLKAQSQEEIRRLWSQLDSARTSRQ 482
Query: 334 ESIGSLRQVLEAKMKL-DRDQLQKQIQLMQKPE 365
E Q+L ++ D +QL+++ + + E
Sbjct: 483 ELSELHEQLLARTSRVEDLEQLKQREKTQHESE 515
Score = 29.6 bits (65), Expect = 4.5
Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 8/90 (8%)
Query: 186 LNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILS-------ARSWLQQ 238
L+ + ++ QS + + H++ L L K V++L +Q+LS RS L+
Sbjct: 1066 LHEKEETLRLQSAQAQPFHQEEKESLSLQLQKKNHQVQQLKDQVLSLSHEIEECRSELEV 1125
Query: 239 EQERIEKELLQKIDQLSLIVKE-NSGASER 267
Q+R E+E + + LS++ + N SER
Sbjct: 1126 LQQRRERENREGANLLSMLKADVNLSHSER 1155
Score = 29.3 bits (64), Expect = 5.9
Identities = 42/196 (21%), Positives = 89/196 (45%), Gaps = 25/196 (12%)
Query: 162 KEQQAAKLILETKIKDAE-GQISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKG 220
KEQ+ + L+ ++ ++ G S LL R++ I EQ + + H L+L D
Sbjct: 2463 KEQEMQGVELQPRLSGSDLGGHSSLLERLEKIIREQGD---LQEKSLEH-LRLPDRS--- 2515
Query: 221 TVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKENSGASERDMEKKLSQMSARL 280
L ++I + R+ L+ + +E LQ + + +L E G+ + ++ ++ A
Sbjct: 2516 ---SLLSEIQALRAQLRMTHLQ-NQEKLQHL-RTALTSAEARGSQQEHQLRRQVELLAY- 2569
Query: 281 DKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEMKA----------EVNAGFT 330
K+E+ + D Q+T EE++ + KL ++++K+ +++
Sbjct: 2570 -KVEQEKCIAGDLQKTLSEEQEKANSVQKLLAAEQTVVRDLKSDLCESRQKSEQLSRSLC 2628
Query: 331 AVYESIGSLRQVLEAK 346
V + + LR +L +K
Sbjct: 2629 EVQQEVLQLRSMLSSK 2644
Score = 28.9 bits (63), Expect = 7.7
Identities = 49/233 (21%), Positives = 96/233 (41%), Gaps = 46/233 (19%)
Query: 144 ARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQL-LNRVDLSISEQSTKLKM 202
A++ +H+ E L KE+ AAK L ++ +G + + DL ++
Sbjct: 1303 AQVVRKHQELLECL----KEESAAKAELALELHKTQGTLEGFKVETADLK------EVLA 1352
Query: 203 SHRDSNHQLQLLDTKFKGTVEELSNQILSARS-----WLQQEQ-----ERIEKELLQKID 252
DS H+L L + +++ + + + R W + E E E L ++++
Sbjct: 1353 GKEDSEHRLVLELESLRRQLQQAAQEQAALREECTRLWSRGEATATDAEAREAALRKEVE 1412
Query: 253 QLSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLEL 312
L+ E +E+D LSQM ++EE Q G + E +T LE
Sbjct: 1413 DLTKEQSETRKQAEKDRSALLSQMKILESELEE-QLSQHRGCAKQAE------AVTALEQ 1465
Query: 313 QMNQNIKEMKAEVNAGFTAVYESIGSLRQVLE---AKMKLDRDQLQKQIQLMQ 362
Q+ K ++ + RQ ++ A+ + +R++ Q++IQ ++
Sbjct: 1466 QVASLDKHLRNQ---------------RQFMDEQAAEREHEREEFQQEIQRLE 1503
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 52.0 bits (123), Expect = 8e-07
Identities = 64/273 (23%), Positives = 121/273 (44%), Gaps = 36/273 (13%)
Query: 92 QLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHK 151
+L +DI+ L+ + + + T + +K L +LSGL D +IA+L+ E K
Sbjct: 950 ELKKDIDDLELTLAKVEKEKHATENKVKNLT-EELSGL----------DETIAKLTREKK 998
Query: 152 TTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRV-DLSIS-EQSTKLKMSHRDSNH 209
E Q + QA E K+ S+L +V DL S EQ KL++
Sbjct: 999 ALQEAHQQALDDLQAE----EDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVD------ 1048
Query: 210 QLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKENSGASERDM 269
L+ K +G ++ IL + QQ ER++K+ + S + E + +
Sbjct: 1049 -LERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQ--F 1105
Query: 270 EKKLSQMSARLDKIEEGQKKTFDGQR-TRQEEEKMHGRITKLELQMNQNIKEMKAEVNAG 328
+KK+ ++ AR++++EE + +R TR + EK + ++++ ++E G
Sbjct: 1106 QKKIKELQARIEELEE----EIEAERATRAKTEKQRSDYARELEELSERLEEA-----GG 1156
Query: 329 FTAVYESIGSLRQVLEAKMKLDRDQLQKQIQLM 361
T+ + R+ K++ D ++ Q + M
Sbjct: 1157 VTSTQIELNKKREAEFLKLRRDLEEATLQHEAM 1189
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 50.8 bits (120), Expect = 2e-06
Identities = 69/366 (18%), Positives = 157/366 (42%), Gaps = 50/366 (13%)
Query: 9 VRTMPRHSQSLTMAPYSSVSLVEQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNK 68
+R + L MA Y S V+QLE + + + +++ ++ +L + +
Sbjct: 132 IRILTCQKTELQMALYYSQHAVKQLEGEA----RDLISRLHDSWKFAGELEQALSAVATQ 187
Query: 69 GGGDRLARLFLEEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLS- 127
+ A ++EE + A+ +L R+ + E+++ + N L E ++
Sbjct: 188 ---KKKADRYIEELTKERDALSLELYRNT-ITDEELKEK-NAKLQEKLQLVESEKSEIQL 242
Query: 128 GLGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLN 187
+ +L+ ++ R A+L + HL KE Q+ L+ ++++ E L N
Sbjct: 243 NVKELKRKLER-----AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENE-----LWN 292
Query: 188 RVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARS-----WLQQEQER 242
R++ E+ + + ++ ++Q + K + E++ Q R W ++E+ R
Sbjct: 293 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR 352
Query: 243 IEKELLQKIDQLSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEK 302
++E++ + ++ +E E M ++ M + +KI E ++K + ++ R++EEK
Sbjct: 353 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 412
Query: 303 MHGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQLQKQIQLMQ 362
Q + I+E + RQ EAKM +++++Q + ++
Sbjct: 413 R---------QEEEKIREQEK----------------RQEQEAKMWRQEEKIREQEEKIR 447
Query: 363 KPETPM 368
+ E M
Sbjct: 448 EQEKKM 453
Score = 39.3 bits (90), Expect = 0.006
Identities = 28/146 (19%), Positives = 72/146 (49%), Gaps = 1/146 (0%)
Query: 223 EELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKENSGASERDMEKKLSQMSARLDK 282
EE Q + W Q+E+ R ++E + + ++ +E E M K+ ++ + +K
Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEK 620
Query: 283 IEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQV 342
I+E ++K + + +E+E+M + + + + E + ++ ++ +R+
Sbjct: 621 IQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIRE- 679
Query: 343 LEAKMKLDRDQLQKQIQLMQKPETPM 368
E K++ +++++Q ++MQ+ E M
Sbjct: 680 QEKKIREQEEKIREQEEMMQEQEEKM 705
Score = 37.0 bits (84), Expect = 0.028
Identities = 60/304 (19%), Positives = 132/304 (43%), Gaps = 24/304 (7%)
Query: 80 EEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARC 139
EE +R ++ + I L+E++ ++ I + ++R+ + ++ R
Sbjct: 376 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 435
Query: 140 DASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEG-QISQLLNRVDLSISEQST 198
+ I + + Q +Q K+ + KI++ E Q + + R + I EQ
Sbjct: 436 EEKIREQEEKIRE-----QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE 490
Query: 199 ----KLKMSHRDSNHQLQ-----LLDTKFKGTVEELSNQILSARSWLQQEQERIEKELL- 248
K KM ++ + Q + K + E++ Q + W Q+E+ R ++E+
Sbjct: 491 IWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQ--EEKMWRQEEKIREQEEMWR 548
Query: 249 --QKIDQLSLIVKENSGASERD-MEKKLSQMSARLDKIEEGQKKTFDGQRTRQE-EEKMH 304
+K+ + I +E + D M ++ ++ + +K+ ++K + + RQE EEKM
Sbjct: 549 EEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMW 608
Query: 305 GRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQLQKQIQLMQKP 364
+ K+ + + I+E + ++ + E + Q E KM +++ +Q + MQ+
Sbjct: 609 KQEEKIR-EQEEKIQEQEEKIREQEEKIREQ-EEMTQEQEEKMGEQEEKMCEQEEKMQEQ 666
Query: 365 ETPM 368
E M
Sbjct: 667 EETM 670
Score = 29.3 bits (64), Expect = 5.9
Identities = 25/132 (18%), Positives = 61/132 (46%), Gaps = 15/132 (11%)
Query: 237 QQEQERIEKELLQKIDQLSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRT 296
Q+E+ + ++E + K ++ R+ E+K+ + +KI E ++K + +
Sbjct: 596 QEEKRQEQEEKMWKQEE-----------KIREQEEKIQEQE---EKIREQEEKIREQEEM 641
Query: 297 RQEEEKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQLQK 356
QE+E+ G + + + ++E + + + E +R+ E K++ + +Q+
Sbjct: 642 TQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIRE-QEEKIREQEEMMQE 700
Query: 357 QIQLMQKPETPM 368
Q + M + E M
Sbjct: 701 QEEKMWEQEEKM 712
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 50.8 bits (120), Expect = 2e-06
Identities = 75/359 (20%), Positives = 156/359 (43%), Gaps = 55/359 (15%)
Query: 30 VEQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNKG--------GGDRLARLF-LE 80
+E++E RI ++T A E I L+ +Q+KG +R RL E
Sbjct: 288 LEEMELRIETQKQTLNARDE-------SIKKLLEMLQSKGLSAKATEEDHERTRRLAEAE 340
Query: 81 EHIRNITAIVKQLNRDIEVLQEQIRAR-DNI--SYGTNSALKTLEMRQLS------GLGD 131
H+ ++ ++++Q ++ +L+E++ R +N S T + +EM+ GL D
Sbjct: 341 MHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRD 400
Query: 132 LRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDL 191
L + ++ A LS E + E ++ + + +K + K+ GQ+ Q L+R D
Sbjct: 401 LEEEIQMLKSNGA-LSTEERE--EEMKQMEVYRSHSKFM-----KNKIGQVKQELSRKDT 452
Query: 192 SISEQSTKLKM---SHRDSNHQLQLLDTKFKGTVEE---LSNQILSARSWLQQEQERIEK 245
+ TKL+ DS +++L + L ++ + R L++++ + K
Sbjct: 453 ELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNK 512
Query: 246 ELLQKIDQLSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHG 305
+ Q D + E G ++ + + K+ QKK + Q +++EK
Sbjct: 513 KTKQIQD-----MAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMS 567
Query: 306 RITKLELQMNQNIKEMKAE---VNAGFTAVYESIGSLRQVLE-AKMKLDRDQLQKQIQL 360
+ + +K ++A+ + T + E++ + +E K + DRD+ +KQ ++
Sbjct: 568 -------SLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEI 619
Score = 38.5 bits (88), Expect = 0.010
Identities = 51/289 (17%), Positives = 120/289 (41%), Gaps = 30/289 (10%)
Query: 90 VKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQL---SGLGDLRGRVARCDASIARL 146
V L + IE LQEQ+R ++ +K+L+ + L L +A + +I RL
Sbjct: 545 VNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERL 604
Query: 147 SAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRD 206
+ Q + L+ K+ +G +S+ + L + E ++ L S
Sbjct: 605 KEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASL-LDLKEHASSLASSGLK 663
Query: 207 SNHQLQLLD----------TKFKGTVEELSNQILSARS--WLQQEQERIEKELLQ----- 249
+ +L+ L+ K + +++ L AR+ + + +E+E+ +
Sbjct: 664 KDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDES 723
Query: 250 -----KIDQLSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMH 304
++D+L I+KE + D +KK++++ ++++ KK + + Q E+K
Sbjct: 724 SKAQAEVDRLLEILKEVEN-EKNDKDKKIAELER---QVKDQNKKVANLKHKEQVEKKKS 779
Query: 305 GRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQ 353
++ + + N+ + ++ + I L + L +++ ++
Sbjct: 780 AQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAER 828
Score = 35.8 bits (81), Expect = 0.063
Identities = 50/234 (21%), Positives = 102/234 (43%), Gaps = 42/234 (17%)
Query: 30 VEQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQN--KGGGDRLARLFLEEHIRNIT 87
V L+ + +K +A ++E A R +D++ +S Q++Q+ + DR+ L EE +R
Sbjct: 765 VANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEEL--EEALRESV 822
Query: 88 AIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLS 147
I + R++ + QE+ AR N L +E + ++ A+LS
Sbjct: 823 QITAE--REMVLAQEE-SARTNAEKQVEELLMAMEKVK-----------QELESMKAKLS 868
Query: 148 AEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDS 207
+ ++ E HL + + LE L + +++ +S +D+
Sbjct: 869 STQQSLAEKETHLTNLRAERRKHLEEV----------------LEMKQEALLAAISEKDA 912
Query: 208 NHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKEN 261
N L L + K T EE++ L++E++R+ ++L Q+ ++ +N
Sbjct: 913 NIALLELSSSKKKTQEEVAA--------LKREKDRLVQQLKQQTQNRMKLMADN 958
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 50.8 bits (120), Expect = 2e-06
Identities = 79/377 (20%), Positives = 165/377 (43%), Gaps = 54/377 (14%)
Query: 17 QSLTMAPYSSVSLVEQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNK-------- 68
Q L +A SS +++ QL + I +T+ +H + + SL K++N+
Sbjct: 92 QELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPE 151
Query: 69 --GGGDRLARLFLE-EHIRN-ITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMR 124
G ++ +L E H+R + ++ +QL ++E N L L R
Sbjct: 152 PPAGPSKVEQLQDETNHLRKELESVGRQLQAEVE---------------NNQMLSLLNRR 196
Query: 125 QLSGLGD----LRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEG 180
Q L + LR + R RL + + E + L +EQ+ E ++++ E
Sbjct: 197 QEERLREQEERLREQEERLREQEERLCEQEERLREQEERL-REQEERLCEQEERLREHEE 255
Query: 181 QISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQ 240
++ + R + EQ +L+ + Q + L + + + E ++ L++++
Sbjct: 256 RLCEQEER----LCEQEERLREQEERLHEQEERLCEQ-EERLREQEERLCEQEERLREQE 310
Query: 241 ERI-EKELLQKIDQLSLIVKENSGASERDMEK--KLSQMSARLDKIE---------EGQK 288
ER+ E+E + + L +E ER +E+ KL + R ++ E E +
Sbjct: 311 ERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVE 370
Query: 289 KTFDGQRTRQEEEKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMK 348
+ + +R RQ++E++ + T EL + ++E++ + G+ A+YE R E
Sbjct: 371 ELLEQERLRQQDERLWQQETLQEL---ERLRELERMLELGWEALYEQRAEPRSGFEELNN 427
Query: 349 LDRD--QLQKQIQLMQK 363
++ QL++Q++ ++K
Sbjct: 428 ENKSTLQLEQQVKELKK 444
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 50.4 bits (119), Expect = 2e-06
Identities = 58/252 (23%), Positives = 109/252 (43%), Gaps = 43/252 (17%)
Query: 149 EHKTTY--EGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVD-------------LSI 193
E + TY EGLQ L + E IK +G I+QL + L +
Sbjct: 180 EMRVTYGTEGLQQLQE--------FEAAIKQRDGIITQLTANLQQARREKDETMREFLEL 231
Query: 194 SEQSTKLKMSHRDSNHQLQLLDTKFKGTVEEL---SNQILSARSWLQQEQERIEKELLQK 250
+EQS KL++ + L ++ T +L QIL+ + L+++ +E +K
Sbjct: 232 TEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEEQDHLLEDYQKKK 291
Query: 251 ID---QLSLIV-----------KENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRT 296
D Q+S + K+ +++ ++++K + + KI E +KKT + +
Sbjct: 292 EDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDK 351
Query: 297 RQEEEKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVL---EAKMKLDRDQ 353
+K+ G + + +Q NQ IK MK E+ +S ++Q++ E K +
Sbjct: 352 LTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKD 411
Query: 354 LQKQIQLMQKPE 365
Q + ++Q+ E
Sbjct: 412 SQFETDIVQRME 423
Score = 47.0 bits (110), Expect = 3e-05
Identities = 70/307 (22%), Positives = 144/307 (46%), Gaps = 42/307 (13%)
Query: 77 LFLEEHI---RNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLR 133
L LEE R + +V++L+ E +Q RAR I+ + + + LS + DL+
Sbjct: 518 LILEEKCALQRQLEDLVEELSFSREQIQ---RARQTIAEQESKLNEA--HKSLSTVEDLK 572
Query: 134 GRVARCDASIARLSAEHK---TTYE-GLQHLNKEQQAAKLILETKIKDAEGQISQLLNRV 189
+ S L +H+ T Y+ L+ L KE+ A +L+ + E ++ +L ++
Sbjct: 573 AEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNA---VLDRMAESQEAELERLRTQL 629
Query: 190 DLSISEQSTKLK----MSHRDSNHQLQ-LLDTKFKGTVEELSNQILSARSWLQQEQERIE 244
S E+ +KLK + HR + +L+ L +K ++ L N+ + Q+ E ++
Sbjct: 630 LFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNE-------MSQKIETMQ 682
Query: 245 KE---LLQKIDQLSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEE 301
E L+ K +QL L + + + + K +M+ +++++ QK+ ++ +E+
Sbjct: 683 FEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINEL---QKEIEILRQEEKEKG 739
Query: 302 KMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQLQKQIQLM 361
+ + +L+L+ K+MK + N + LEA+ + +D+ +K ++ M
Sbjct: 740 TLEQEVQELQLKTELLEKQMKEKEN--------DLQEKFAQLEAENSILKDE-KKTLEDM 790
Query: 362 QKPETPM 368
K TP+
Sbjct: 791 LKIHTPV 797
Score = 44.3 bits (103), Expect = 2e-04
Identities = 71/374 (18%), Positives = 149/374 (39%), Gaps = 68/374 (18%)
Query: 32 QLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNI----- 86
+L+D++ +K L E + +I N ++ N +R + +++ + +
Sbjct: 347 ELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQK 406
Query: 87 ---------TAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVA 137
T IV+++ ++ + EQ+RA + YG E+ +R +A
Sbjct: 407 RNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQEL--------IRQHMA 458
Query: 138 RCDASIARLSAEHKTTYEGLQHLNKEQQAAKLI------LETKIKDAEGQISQLLNRVDL 191
+ + R E + ++ + KL+ L K++D Q +L + L
Sbjct: 459 QMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGL 518
Query: 192 SISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELS---NQILSARSWLQQEQERIE---K 245
+ E+ L + + VEELS QI AR + +++ ++ K
Sbjct: 519 ILEEKCA---------------LQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHK 563
Query: 246 ELLQKIDQLSLIVKENSGASERDMEKKLS-------------QMSARLDKIEEGQKKTFD 292
L D + IV + E +++ + + +A LD++ E Q+ +
Sbjct: 564 SLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELE 623
Query: 293 GQRTR---QEEEKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESI-GSLRQVLEAKMK 348
RT+ EE++ LE++ NI+++K + + + + + Q +E M+
Sbjct: 624 RLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIET-MQ 682
Query: 349 LDRDQL-QKQIQLM 361
++D L KQ QL+
Sbjct: 683 FEKDNLITKQNQLI 696
Score = 33.9 bits (76), Expect = 0.24
Identities = 37/177 (20%), Positives = 74/177 (41%), Gaps = 32/177 (18%)
Query: 149 EHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISE------QSTKLKM 202
E +T E L E++ L L+ K+ A+ + +L ++ E + T K
Sbjct: 326 EKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQ 385
Query: 203 SHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKENS 262
R S+ +++ L GTVEEL + + + E +++Q+++Q
Sbjct: 386 KERQSSEEIKQL----MGTVEELQKR--------NHKDSQFETDIVQRMEQ--------- 424
Query: 263 GASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIK 319
+ ++KL Q+ A LD++ Q + RQ +M T+ + +M ++
Sbjct: 425 -----ETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALR 476
Score = 30.0 bits (66), Expect = 3.4
Identities = 38/169 (22%), Positives = 77/169 (45%), Gaps = 18/169 (10%)
Query: 191 LSISEQSTKLK---MSHRDSNHQLQLLD-TKFKGTVEELSNQILSARSWLQQEQERIEKE 246
LSI Q T L+ ++H+ LQ L+ TK + V+EL + I S + L++ ++ E E
Sbjct: 1305 LSIHSQMTNLEDIDVNHKSKLSSLQDLEKTKLEEQVQELESLISSLQQQLKETEQNYEAE 1364
Query: 247 L------LQKIDQLSL---IVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTR 297
+ LQ + + ++ + ++ +E D ++ + S I+ + F G+
Sbjct: 1365 IHCLQKRLQAVSESTVPPSLPVDSVVITESDAQRTMYPGSCVKKNIDGTIE--FSGEFGV 1422
Query: 298 QEEEKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAK 346
+EE + + LE Q + ++E A+V + + L ++ K
Sbjct: 1423 KEETNI---VKLLEKQYQEQLEEEVAKVIVSMSIAFAQQTELSRISGGK 1468
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 50.4 bits (119), Expect = 2e-06
Identities = 58/252 (23%), Positives = 109/252 (43%), Gaps = 43/252 (17%)
Query: 149 EHKTTY--EGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVD-------------LSI 193
E + TY EGLQ L + E IK +G I+QL + L +
Sbjct: 180 EMRVTYGTEGLQQLQE--------FEAAIKQRDGIITQLTANLQQARREKDETMREFLEL 231
Query: 194 SEQSTKLKMSHRDSNHQLQLLDTKFKGTVEEL---SNQILSARSWLQQEQERIEKELLQK 250
+EQS KL++ + L ++ T +L QIL+ + L+++ +E +K
Sbjct: 232 TEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEEQDHLLEDYQKKK 291
Query: 251 ID---QLSLIV-----------KENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRT 296
D Q+S + K+ +++ ++++K + + KI E +KKT + +
Sbjct: 292 EDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDK 351
Query: 297 RQEEEKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVL---EAKMKLDRDQ 353
+K+ G + + +Q NQ IK MK E+ +S ++Q++ E K +
Sbjct: 352 LTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKD 411
Query: 354 LQKQIQLMQKPE 365
Q + ++Q+ E
Sbjct: 412 SQFETDIVQRME 423
Score = 47.0 bits (110), Expect = 3e-05
Identities = 70/307 (22%), Positives = 144/307 (46%), Gaps = 42/307 (13%)
Query: 77 LFLEEHI---RNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLR 133
L LEE R + +V++L+ E +Q RAR I+ + + + LS + DL+
Sbjct: 518 LILEEKCALQRQLEDLVEELSFSREQIQ---RARQTIAEQESKLNEA--HKSLSTVEDLK 572
Query: 134 GRVARCDASIARLSAEHK---TTYE-GLQHLNKEQQAAKLILETKIKDAEGQISQLLNRV 189
+ S L +H+ T Y+ L+ L KE+ A +L+ + E ++ +L ++
Sbjct: 573 AEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNA---VLDRMAESQEAELERLRTQL 629
Query: 190 DLSISEQSTKLK----MSHRDSNHQLQ-LLDTKFKGTVEELSNQILSARSWLQQEQERIE 244
S E+ +KLK + HR + +L+ L +K ++ L N+ + Q+ E ++
Sbjct: 630 LFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNE-------MSQKIETMQ 682
Query: 245 KE---LLQKIDQLSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEE 301
E L+ K +QL L + + + + K +M+ +++++ QK+ ++ +E+
Sbjct: 683 FEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINEL---QKEIEILRQEEKEKG 739
Query: 302 KMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQLQKQIQLM 361
+ + +L+L+ K+MK + N + LEA+ + +D+ +K ++ M
Sbjct: 740 TLEQEVQELQLKTELLEKQMKEKEN--------DLQEKFAQLEAENSILKDE-KKTLEDM 790
Query: 362 QKPETPM 368
K TP+
Sbjct: 791 LKIHTPV 797
Score = 44.3 bits (103), Expect = 2e-04
Identities = 71/374 (18%), Positives = 149/374 (39%), Gaps = 68/374 (18%)
Query: 32 QLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNI----- 86
+L+D++ +K L E + +I N ++ N +R + +++ + +
Sbjct: 347 ELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQK 406
Query: 87 ---------TAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVA 137
T IV+++ ++ + EQ+RA + YG E+ +R +A
Sbjct: 407 RNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQEL--------IRQHMA 458
Query: 138 RCDASIARLSAEHKTTYEGLQHLNKEQQAAKLI------LETKIKDAEGQISQLLNRVDL 191
+ + R E + ++ + KL+ L K++D Q +L + L
Sbjct: 459 QMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGL 518
Query: 192 SISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELS---NQILSARSWLQQEQERIE---K 245
+ E+ L + + VEELS QI AR + +++ ++ K
Sbjct: 519 ILEEKCA---------------LQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHK 563
Query: 246 ELLQKIDQLSLIVKENSGASERDMEKKLS-------------QMSARLDKIEEGQKKTFD 292
L D + IV + E +++ + + +A LD++ E Q+ +
Sbjct: 564 SLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELE 623
Query: 293 GQRTR---QEEEKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESI-GSLRQVLEAKMK 348
RT+ EE++ LE++ NI+++K + + + + + Q +E M+
Sbjct: 624 RLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIET-MQ 682
Query: 349 LDRDQL-QKQIQLM 361
++D L KQ QL+
Sbjct: 683 FEKDNLITKQNQLI 696
Score = 33.9 bits (76), Expect = 0.24
Identities = 37/177 (20%), Positives = 74/177 (41%), Gaps = 32/177 (18%)
Query: 149 EHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISE------QSTKLKM 202
E +T E L E++ L L+ K+ A+ + +L ++ E + T K
Sbjct: 326 EKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQ 385
Query: 203 SHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKENS 262
R S+ +++ L GTVEEL + + + E +++Q+++Q
Sbjct: 386 KERQSSEEIKQL----MGTVEELQKR--------NHKDSQFETDIVQRMEQ--------- 424
Query: 263 GASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIK 319
+ ++KL Q+ A LD++ Q + RQ +M T+ + +M ++
Sbjct: 425 -----ETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALR 476
Score = 30.0 bits (66), Expect = 3.4
Identities = 38/169 (22%), Positives = 77/169 (45%), Gaps = 18/169 (10%)
Query: 191 LSISEQSTKLK---MSHRDSNHQLQLLD-TKFKGTVEELSNQILSARSWLQQEQERIEKE 246
LSI Q T L+ ++H+ LQ L+ TK + V+EL + I S + L++ ++ E E
Sbjct: 1305 LSIHSQMTNLEDIDVNHKSKLSSLQDLEKTKLEEQVQELESLISSLQQQLKETEQNYEAE 1364
Query: 247 L------LQKIDQLSL---IVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTR 297
+ LQ + + ++ + ++ +E D ++ + S I+ + F G+
Sbjct: 1365 IHCLQKRLQAVSESTVPPSLPVDSVVITESDAQRTMYPGSCVKKNIDGTIE--FSGEFGV 1422
Query: 298 QEEEKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAK 346
+EE + + LE Q + ++E A+V + + L ++ K
Sbjct: 1423 KEETNI---VKLLEKQYQEQLEEEVAKVIVSMSIAFAQQTELSRISGGK 1468
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 50.4 bits (119), Expect = 2e-06
Identities = 67/351 (19%), Positives = 150/351 (42%), Gaps = 29/351 (8%)
Query: 42 KTTAALVEHAFRIKDDIVNSLQKMQNKGGG-------DRLARLFLEEHIRNITAIVKQLN 94
K A +E A + +D+++ L+K+Q + R +R + + +K L
Sbjct: 1627 KDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLE 1686
Query: 95 RDIEVLQEQI----RARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEH 150
+I LQE++ RAR + + + SG L R +A IA+L E
Sbjct: 1687 AEILQLQEELASSERARRHAEQERDELADEIT-NSASGKSALLDEKRRLEARIAQLEEEL 1745
Query: 151 KTTYEGLQHLNKEQQAAKLILETKIKD--AEGQISQLLNRVDLSISEQSTKLKMSHRDSN 208
+ ++ LN + L ++T + AE +Q + + Q+ +LK ++
Sbjct: 1746 EEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELE 1805
Query: 209 HQLQLLDTKFKGTVEELSNQILSARSWLQQEQE------RIEKELLQKIDQLSLIVKENS 262
++ +KFK T+ L +I L+QE + ++ + +K+ ++ + V++
Sbjct: 1806 GAVK---SKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDER 1862
Query: 263 GASER---DMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIK 319
+++ MEK ++M ++EE +++ +R++ ++ T+ +++ +
Sbjct: 1863 RHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVS 1922
Query: 320 EMKAEVNAGFTAVYESIGSLRQVLE---AKMKLDRDQLQKQIQLMQKPETP 367
+K + G + S S R+ L A ++L D + + + + + P
Sbjct: 1923 TLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDDDTESKTSDVNETQPP 1973
Score = 41.6 bits (96), Expect = 0.001
Identities = 69/327 (21%), Positives = 142/327 (43%), Gaps = 34/327 (10%)
Query: 41 EKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNITAIVKQLNRDIEVL 100
EK+ AL + +++ L++++++ A+L LE N+ A+ Q RD++
Sbjct: 1531 EKSKRALEQQV----EEMRTQLEELEDELQATEDAKLRLEV---NMQAMKAQFERDLQTR 1583
Query: 101 QEQIRARDNISYGTNSALKTLEMRQLSG-LGDLRGRVARCDASIARLSAEHKTTYEGLQH 159
EQ + L ++R+L L D R + A AS ++ + K ++
Sbjct: 1584 DEQNEEKKR--------LLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEA 1635
Query: 160 LNKEQ-QAAKLI--LETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDT 216
NK + + K + L+ ++KD + ++ + D I QS ++S +L+ L+
Sbjct: 1636 ANKARDEVIKQLRKLQAQMKDYQRELEEARASRD-EIFAQS-------KESEKKLKSLEA 1687
Query: 217 KFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKENSGASER--DMEKKLS 274
+ EEL++ AR +QE++ + E+ S ++ E R +E++L
Sbjct: 1688 EILQLQEELASSE-RARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELE 1746
Query: 275 QMSARLDKIEEGQKKTFDGQRTRQEE----EKMHGRITKLELQMNQNIKEMKAEVNAGFT 330
+ + ++ + + +KT T E + Q+ + KE+KA++
Sbjct: 1747 EEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEG 1806
Query: 331 AVYESIGSLRQVLEAKMKLDRDQLQKQ 357
AV + LEAK+ +QL+++
Sbjct: 1807 AVKSKFKATISALEAKIGQLEEQLEQE 1833
Score = 35.8 bits (81), Expect = 0.063
Identities = 62/340 (18%), Positives = 149/340 (43%), Gaps = 51/340 (15%)
Query: 29 LVEQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNITA 88
++ LE R+ E+ L +++ I + +++ + G AR L+ A
Sbjct: 923 ILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEG----ARQKLQLEKVTAEA 978
Query: 89 IVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDA------- 141
+K++ +I +L++Q NS K ++ ++L + R+A C +
Sbjct: 979 KIKKMEEEILLLEDQ-----------NS--KFIKEKKL-----MEDRIAECSSQLAEEEE 1020
Query: 142 ---SIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRV-DLSISEQS 197
++A++ + + L+ K+++ + LE + +G+ + L +++ +L
Sbjct: 1021 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDE 1080
Query: 198 TKLKMSHRDSNHQLQLL----DTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQ 253
KL+++ ++ Q L +T K ++ ++ + + LQ++ E EK K ++
Sbjct: 1081 LKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFES-EKASRNKAEK 1139
Query: 254 LSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQ 313
+ E A + ++E L +A+ + + +++ + ++ +EE K H E Q
Sbjct: 1140 QKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNH------EAQ 1193
Query: 314 MNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQ 353
+ Q++++ A TA+ E L Q K L++++
Sbjct: 1194 I-QDMRQRHA------TALEELSEQLEQAKRFKANLEKNK 1226
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 50.4 bits (119), Expect = 2e-06
Identities = 54/293 (18%), Positives = 123/293 (41%), Gaps = 33/293 (11%)
Query: 80 EEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARC 139
EE + +++++ L I L + + S + L S L L + +
Sbjct: 458 EEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQ 517
Query: 140 DASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTK 199
D +A L + K L ++Q+ A L +++ Q+S L + + + E + K
Sbjct: 518 DQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVE----QLSSSLKQKEQQLKEVAEK 573
Query: 200 LKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKID------Q 253
+ + +D QL T E L R ++ E +EKE K++ Q
Sbjct: 574 QEATRQDHAQQL--------ATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQ 625
Query: 254 LSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQ 313
++ ++++ S +++ +++S ++++++ + RQE+ + ++ +LELQ
Sbjct: 626 VANEARDSAQTSVTQAQREKAELSRKVEELQACV------ETARQEQHEAQAQVAELELQ 679
Query: 314 M---------NQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQLQKQ 357
+ + + + K ++ A+ ES+ + LE + + D L++Q
Sbjct: 680 LRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQ 732
Score = 39.3 bits (90), Expect = 0.006
Identities = 79/416 (18%), Positives = 158/416 (37%), Gaps = 76/416 (18%)
Query: 7 RRVRTMPRHSQSLTMAPYSSVSLVEQLEDRILC----HEKTTAALVEHAFRIKDDIVNSL 62
R++ + + L+ S ++QL+D + H K T +E +++ ++ +L
Sbjct: 311 RKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAAL 370
Query: 63 QKMQNKGGGDRLARLFLEEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLE 122
Q + LEE + + QL + LQ+ G L+TL+
Sbjct: 371 QDKK-----------CLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLK 419
Query: 123 MRQLSGLGD---LRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILE-----TK 174
+ + L+ RV + R E K E ++QQ + LI + +
Sbjct: 420 QEAATLAANNTQLQARVEMLETE--RGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISN 477
Query: 175 IKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARS 234
+ A+ ++ Q ++ Q L N +Q D + G ++ +
Sbjct: 478 LSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQ 537
Query: 235 WLQQEQERIEKELLQKIDQLSLIVK----------------------------ENSGASE 266
LQQ QE+ + L +++QLS +K E AS
Sbjct: 538 TLQQ-QEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASL 596
Query: 267 RDMEKKLSQMSA----RLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEMK 322
R+ + L Q+ A + K+E Q++ R + + + + ++++ ++E++
Sbjct: 597 RERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQ 656
Query: 323 AEVNAGFTAVYESIGSLRQVLEAKMKL---------------DRDQLQKQIQLMQK 363
A V TA E + QV E +++L ++DQLQ+Q+Q +++
Sbjct: 657 ACVE---TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKE 709
Score = 33.5 bits (75), Expect = 0.31
Identities = 57/296 (19%), Positives = 128/296 (43%), Gaps = 24/296 (8%)
Query: 72 DRLARLFLEEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTN---SALKTLEMRQLSG 128
++ AR LE ++N + + + LQE + G + + L+ LE Q+
Sbjct: 1023 EKAARAELEMRLQNA---LNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKE 1079
Query: 129 LGDLRGRVARCDASIARLSAEHKTTYEGLQHL---NKEQQAAKL-ILETKIKDAEGQISQ 184
L +LR V + +A+ EH + G Q E KL L ++ E Q +
Sbjct: 1080 LEELRQTVKQLKEQLAKKEKEH-ASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQK 1138
Query: 185 LLNRVD-LSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERI 243
+ D L S ++ + + RDS L+T +G +EE + ++ ++S L Q +
Sbjct: 1139 QQEQADSLERSLEAERASRAERDS-----ALET-LQGQLEEKAQELGHSQSALASAQREL 1192
Query: 244 E--KELLQKIDQLSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEE 301
+ +Q + K ++ E+K S +S+ +++ ++ + + +E +
Sbjct: 1193 AAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELK 1252
Query: 302 KMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQLQKQ 357
++ ++ ++ + ++ ++AE + E +LR+ +++ R++ +KQ
Sbjct: 1253 RLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSL----REEAEKQ 1304
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 50.4 bits (119), Expect = 2e-06
Identities = 76/387 (19%), Positives = 164/387 (42%), Gaps = 70/387 (18%)
Query: 31 EQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQ-----KMQNKGGGDRLARLFLEEHIRN 85
E+++ + ++ + L FR++ +L+ K +NK L+E I +
Sbjct: 1510 EEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKN---------LQEEISD 1560
Query: 86 ITAIVKQLNRDIEVLQEQIRARDNISYGTNSALK----TLEMRQLSGL----------GD 131
+T V + I+ L++ +A + +AL+ LE+ + L +
Sbjct: 1561 LTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAE 1620
Query: 132 LRGRVARCDASIARLSAEHKTTYEGLQ-HLNKEQQAAKLILETKIKDAEGQISQLLNRVD 190
+ ++A D A L H+ E LQ L+ E +A L K K EG ++ L ++
Sbjct: 1621 VDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLK-KKMEGDLNDLELQLG 1679
Query: 191 LSISEQSTKLKMSHR---------------------DSNHQLQLLDTKFKGTVEELSNQI 229
+ + Q+T+ + + R + + Q Q L+ + EL ++
Sbjct: 1680 HA-TRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELE-EL 1737
Query: 230 LSARSWLQQEQERIEKELLQKIDQLSLIVKENSGA--SERDMEKKLSQMSARLDKI---- 283
+A ++ + E+ELL+ ++L+L+ +N+G ++ +E L+Q+S +++
Sbjct: 1738 RAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQER 1797
Query: 284 ----EEGQKKTFDGQRTRQE---EEKMHGRITKLELQMNQNIKEMKAEVNAGFTAVYESI 336
E+ +K D +E E+ + +++ + Q ++E++A + A
Sbjct: 1798 REAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGG 1857
Query: 337 GSLRQVLEAKMKLDRDQLQKQIQLMQK 363
Q LEAK++ +L+ ++ QK
Sbjct: 1858 KKQVQKLEAKVR----ELEAELDAEQK 1880
Score = 50.1 bits (118), Expect = 3e-06
Identities = 61/266 (22%), Positives = 113/266 (42%), Gaps = 48/266 (18%)
Query: 92 QLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHK 151
+L +DI+ L+ + + T + +K +L +A D S+ARL+ E K
Sbjct: 998 ELKKDIDDLKLTLAKAEKEKQATENKVK-----------NLTEEMAALDESVARLTKEKK 1046
Query: 152 TTYEGLQHLNKEQQA----------AKLILETKIKDAEGQISQLLNRVDLSISEQSTKLK 201
E Q + QA AKL LE +++D E + EQ KL+
Sbjct: 1047 ALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSL------------EQEKKLR 1094
Query: 202 MSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKEN 261
M + +L+ G ++ + A QQ +E+++K+ ++ QLSL V++
Sbjct: 1095 MDTERAKRKLE-------GDLKLTQESVADAAQDKQQLEEKLKKKD-SELSQLSLRVEDE 1146
Query: 262 SGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKE- 320
+ M+KK+ ++ AR +++EE + + R EK + ++++ ++E
Sbjct: 1147 QLLGAQ-MQKKIKELQARAEELEEELEAE---RAARARVEKQRAEAARELEELSERLEEA 1202
Query: 321 --MKAEVNAGFTAVYESIGSLRQVLE 344
A G +G LR+ LE
Sbjct: 1203 GGASAGQREGCRKREAELGRLRRELE 1228
Score = 39.3 bits (90), Expect = 0.006
Identities = 79/357 (22%), Positives = 152/357 (42%), Gaps = 48/357 (13%)
Query: 29 LVEQLEDRILCHEKTTAAL----VEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIR 84
L +LE+ L HE T AAL E A + + V+SLQ+++ K ++ L +
Sbjct: 1223 LRRELEEAALRHEATVAALRRKQAEGAAELGEQ-VDSLQRVRQKLEKEKSE---LRMEVD 1278
Query: 85 NITAIVKQLNRDIEVLQEQIRA-RDNISYGTNSALKTLEM-RQLSGLGDLRGRVARCDAS 142
++ A V+ L R ++ R D +S + +K E+ RQL+ RGR+
Sbjct: 1279 DLAANVETLTRAKASAEKLCRTYEDQLS---EAKIKVEELQRQLADASTQRGRLQTESGE 1335
Query: 143 IARLSAEHK------TTYEGLQHLNKEQQAAKLILETKIKDAEGQISQ-------LLNRV 189
++RL E + + + L + E+ +L E+K K A Q LL
Sbjct: 1336 LSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQ 1395
Query: 190 DLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARS----WLQQEQERIE- 244
+E +L+ +N ++ +K++ + + ++ A+ LQ+ +E +E
Sbjct: 1396 HEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEA 1455
Query: 245 -KELLQKIDQLSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKM 303
+++ L ++ S ++E+ S +A LDK + ++ + +R RQEEE
Sbjct: 1456 ANAKCSSLEKAKLRLQTESEDVTLELERATS-AAAALDKKQRHLERALE-ERRRQEEE-- 1511
Query: 304 HGRITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEA--KMKLDRDQLQKQI 358
M + ++ + E T ++ + LEA +K + LQ++I
Sbjct: 1512 ----------MQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEI 1558
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 50.1 bits (118), Expect = 3e-06
Identities = 60/272 (22%), Positives = 122/272 (44%), Gaps = 42/272 (15%)
Query: 92 QLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHK 151
+L +DI+ L+ + + + T + +K L +++GL ++ IA+L+ E K
Sbjct: 951 ELKKDIDDLELTLAKVEKEKHATENKVKNLT-EEMAGLDEI----------IAKLTKEKK 999
Query: 152 TTYEG----LQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDS 207
E L L E+ + ++K+K E Q+ L + EQ K++M
Sbjct: 1000 ALQEAHQQALDDLQVEEDKVNSLSKSKVK-LEQQVDDLEGSL-----EQEKKVRMD---- 1049
Query: 208 NHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKENSGASER 267
L+ K +G ++ I+ + Q +E+++K+ Q S I E A +
Sbjct: 1050 ---LERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQ- 1105
Query: 268 DMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEM--KAEV 325
++KKL + AR++++EE + +RT + ++ KL +++ ++E+ + E
Sbjct: 1106 -LQKKLKENQARIEELEE----ELEAERTAR------AKVEKLRSDLSRELEEISERLEE 1154
Query: 326 NAGFTAVYESIGSLRQVLEAKMKLDRDQLQKQ 357
G T+V + R+ KM+ D ++ Q
Sbjct: 1155 AGGATSVQIEMNKKREAEFQKMRRDLEEATLQ 1186
Score = 43.9 bits (102), Expect = 2e-04
Identities = 52/277 (18%), Positives = 125/277 (45%), Gaps = 41/277 (14%)
Query: 116 SALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKI 175
S+L+ + R + + DL V R +A+ A L + + + L ++ + ++ LE+
Sbjct: 1414 SSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQ 1473
Query: 176 KDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSN--QILSAR 233
K+A S+S + KLK ++ +S L+ + K EE+S+ + L
Sbjct: 1474 KEAR------------SLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEG 1521
Query: 234 SWLQQEQERIEKELLQKIDQLSLIVKENSGASER-----------------DMEKKLSQM 276
E E++ K+L + +L ++E + E ++E+KL++
Sbjct: 1522 GKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEK 1581
Query: 277 SARLDKIEEGQKKTFDGQRTRQE-EEKMHGRITKLELQMNQNIKEMKAEV---NAGFTAV 332
+++ + ++ D +T + E + + +++ +M ++ EM+ ++ N
Sbjct: 1582 DEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEA 1641
Query: 333 YESIGSLRQVL-EAKMKLD-----RDQLQKQIQLMQK 363
+ + SL+ +L + +++LD D L++ I ++++
Sbjct: 1642 QKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVER 1678
>gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens]
Length = 1044
Score = 50.1 bits (118), Expect = 3e-06
Identities = 70/335 (20%), Positives = 133/335 (39%), Gaps = 52/335 (15%)
Query: 41 EKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARL--FLEEHIRNITAIVKQLNRDIE 98
+K L++ A + D+ K K +L R E I+ A + QL D +
Sbjct: 580 KKQAMLLLQRALAQQRDLTARRVKETEKALSRQLQRQREHYEATIQRHLAFIDQLIEDKK 639
Query: 99 VLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQ 158
VL E+ A + +L+ RC +A+ A+H+ + L+
Sbjct: 640 VLSEKCEAV---------------------VAELKQEDQRCTERVAQAQAQHELEIKKLK 678
Query: 159 HLNKEQQAA----------KLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSN 208
L + A K I E ++ E +I +L+ R K ++ S
Sbjct: 679 ELMSATEKARREKWISEKTKKIKEVTVRGLEPEIQKLIAR---------HKQEVRRLKSL 729
Query: 209 HQLQLLDTKFKGT------VEELSNQILSARSWL-QQEQERIEKELLQKIDQLSLIVKEN 261
H+ +LL + + + EEL Q+ + L QQE+ER + ++++L ++E+
Sbjct: 730 HEAELLQSDERASQRCLRQAEELREQLEREKEALGQQERERARQRQRAELEELRQQLEES 789
Query: 262 SGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEM 321
S A R + + + ++ + + T Q + + GR K E + +E+
Sbjct: 790 SSALTRALRAEFEKGREEQERRHQMELNTLKQQLELERQAWEAGRTRKEEAWLLNREQEL 849
Query: 322 KAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQLQK 356
+ E+ G + I + LEA M L +++ +K
Sbjct: 850 REEIRKGRD---KEIELVIHRLEADMALAKEESEK 881
>gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo
sapiens]
Length = 1002
Score = 49.7 bits (117), Expect = 4e-06
Identities = 70/300 (23%), Positives = 128/300 (42%), Gaps = 44/300 (14%)
Query: 91 KQLNRDIEVLQEQIRA----RDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIA-- 144
+ L ++ L+E++R + + K LEM +L L+ +RC+A A
Sbjct: 308 EDLKQEKSELEEKLRVLVTEKAGMQLNLEELQKKLEMTELL----LQQFSSRCEAPDANQ 363
Query: 145 --RLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAE---GQISQLLNRVDLSISEQSTK 199
+ + E + E HL + ++ + + + K AE G+ + R+ +SEQ
Sbjct: 364 QLQQAMEERAQLEA--HLGQVMESVRQLQMERDKYAENLKGESAMWRQRMQ-QMSEQVHT 420
Query: 200 LKMSHRDSNHQLQLLDTKFKGTVEELSNQILS------------ARSWLQQEQERIEKEL 247
L+ S ++Q L+T ++ EL NQ+ LQ E E + KEL
Sbjct: 421 LREEKECSMSRVQELET----SLAELRNQMAEPPPPEPPAGPSEVEQQLQAEAEHLRKEL 476
Query: 248 LQKIDQLSLIVKENSGASE--RDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHG 305
QL V++N G S R+ E++L ++ + E + RQ E M
Sbjct: 477 EGLAGQLQAQVQDNEGLSRLNREQEERLLELERAAELWGE------QAEARRQILETMQN 530
Query: 306 RITKLELQMNQN--IKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQLQKQIQLMQK 363
T + ++QN +KE AE+ +GF + + L+++ + R+ +K +L +K
Sbjct: 531 DRTTISRALSQNRELKEQLAELQSGFVKLTNENMEITSALQSEQHVKRELGKKLGELQEK 590
Score = 33.5 bits (75), Expect = 0.31
Identities = 54/245 (22%), Positives = 109/245 (44%), Gaps = 39/245 (15%)
Query: 127 SGLGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLL 186
+ L DL R + ++ +K ++ L ++ Q LE + K+ + L
Sbjct: 154 ANLKDLESRYQQLAVALDSSYVTNKQLNITIEKLKQQNQEITDQLEEEKKECHQKQGAL- 212
Query: 187 NRVDLSISEQSTKLKMSHRDSNHQLQLLDTKF-----KGTVEELSNQI------------ 229
R L + Q+ + +S + + Q L T+ +G E+L++++
Sbjct: 213 -REQLQVHIQTIGILVSEK-AELQTALAHTQHAARQKEGESEDLASRLQYSRRRVGELER 270
Query: 230 -LSARSWLQQEQERIEKELLQKIDQLSLIVKENSGASERDMEKKLSQMSARLDKIEEGQK 288
LSA S Q++ +R KEL ++ D L L + +N+ ++E D++++ S++ +L + +
Sbjct: 271 ALSAVSTQQKKADRYNKELTKERDALRLELYKNTQSNE-DLKQEKSELEEKLRVLVTEKA 329
Query: 289 KTFDGQRTRQEEEKMHGRITKLELQM----------NQNIK---EMKAEVNAGFTAVYES 335
G + EE + +T+L LQ NQ ++ E +A++ A V ES
Sbjct: 330 ----GMQLNLEELQKKLEMTELLLQQFSSRCEAPDANQQLQQAMEERAQLEAHLGQVMES 385
Query: 336 IGSLR 340
+ L+
Sbjct: 386 VRQLQ 390
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 49.7 bits (117), Expect = 4e-06
Identities = 62/335 (18%), Positives = 139/335 (41%), Gaps = 31/335 (9%)
Query: 35 DRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNITAIVKQLN 94
+R+ + + VE + K+D+ + K + EE+ + + +++L
Sbjct: 1769 ERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLE 1828
Query: 95 RDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTTY 154
++ LQ+++ + ++ + ++ + L + R V +A +
Sbjct: 1829 LNVRKLQQELDQLNRDKLSLHNDISAMQQQ----LQEKREAVNSLQEELANVQDHLNLAK 1884
Query: 155 EGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLL 214
+ L H K Q +L ++ + IS+ NR + E+ TK QLQ+L
Sbjct: 1885 QDLLHTTKHQD----VLLSEQTRLQKDISEWANRFEDCQKEEETK--------QQQLQVL 1932
Query: 215 DTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKENSGASERDMEKKLS 274
+ +EE +++ Q+ Q+ E E K++ + +KE + +EK+L+
Sbjct: 1933 QNE----IEENKLKLVQQEMMFQRLQKERESEE-SKLETSKVTLKEQ----QHQLEKELT 1983
Query: 275 QMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEMK---AEVNAGFTA 331
++LD++ + RT QEEE+ + K Q + + E + E + A
Sbjct: 1984 DQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLA 2043
Query: 332 VYESIGSLR---QVLEAKMKLDRDQLQKQIQLMQK 363
+ + S+R +L + +R + +KQ+ +++
Sbjct: 2044 LQKEADSMRADFSLLRNQFLTERKKAEKQVASLKE 2078
Score = 38.1 bits (87), Expect = 0.013
Identities = 75/373 (20%), Positives = 147/373 (39%), Gaps = 79/373 (21%)
Query: 28 SLVEQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNIT 87
S +E+LE + ++ L + +DI Q++Q K R A L+E + N+
Sbjct: 1822 SNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEK----REAVNSLQEELANVQ 1877
Query: 88 AIVKQLNRDI--------EVLQEQIRARDNISYGTN--------SALKTLEMRQLSG-LG 130
+ +D+ +L EQ R + +IS N K +++ L +
Sbjct: 1878 DHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIE 1937
Query: 131 DLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRV- 189
+ + ++ + + RL E ++ L+ + + LE ++ D + ++ Q+L++V
Sbjct: 1938 ENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVL 1997
Query: 190 -----------------DLSISEQSTKLKMSHRDSN-------------------HQLQL 213
L + TK ++S R+ L
Sbjct: 1998 AAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSL 2057
Query: 214 LDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKE---------NSGA 264
L +F ++ Q+ S + L+ ++ ++EK LL++ + S I KE ++
Sbjct: 2058 LRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHE 2117
Query: 265 SERDMEKKLSQMS----------ARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQM 314
R + K+L+QM A +E Q + D RT + E K R T L+ +
Sbjct: 2118 RARRLMKELNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIR-TSLK-NL 2175
Query: 315 NQNIKEMKAEVNA 327
NQ + E+ A++ A
Sbjct: 2176 NQFLPELPADLEA 2188
Score = 37.7 bits (86), Expect = 0.017
Identities = 58/289 (20%), Positives = 116/289 (40%), Gaps = 25/289 (8%)
Query: 74 LARLFLEEHIRNITAIVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLR 133
L RL E R+ IV D E +++++ ++ + +L+ Q GDL
Sbjct: 650 LQRLTEVEQERDQLEIVAM---DAENMRKELAELESALQEQHEVNASLQQTQ----GDLS 702
Query: 134 GRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSI 193
A +A + AE E L+ + + Q + L+ +++ + L + S
Sbjct: 703 AYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSE 762
Query: 194 SEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQ 253
++ ++ H H LQ + K +++ N + L + +E + ++D+
Sbjct: 763 EKEQENSEL-HAKLKH-LQDDNNLLKQQLKDFQNHLNHVVDGLVRPEE-----VAARVDE 815
Query: 254 LSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQ 313
L +K +G E + S L K +K F R + E+ ++ + +LQ
Sbjct: 816 LRRKLKLGTG------EMNIHSPSDVLGKSLADLQKQFSEILARSKWERDEAQVRERKLQ 869
Query: 314 MNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRDQLQKQIQLMQ 362
+++ K T E + + LEA+M D+ Q + +IQ M+
Sbjct: 870 EEMALQQEKLA-----TGQEEFRQACERALEARMNFDKRQHEARIQQME 913
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 49.3 bits (116), Expect = 5e-06
Identities = 72/343 (20%), Positives = 137/343 (39%), Gaps = 33/343 (9%)
Query: 17 QSLTMAPYSSVSLVEQLEDRILC--HEKTTAALVEHAFRIKDDIVNSLQKM--QNKGGGD 72
QSL + L +LED + EK+ +E ++ V L++ NK GD
Sbjct: 471 QSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGD 530
Query: 73 RLARLFLEEHIRNITAIVKQLN----RDIEVLQEQIRARDNISYGTNSALKTLEMRQLSG 128
L L + I ++ ++ R+I L+E AR+ AL T
Sbjct: 531 VDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYT-------- 582
Query: 129 LGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNR 188
+ +LS E+++ L+H NKE + ++K++ A Q +
Sbjct: 583 -------------ATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEE 629
Query: 189 VDLSISEQSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELL 248
+ +S S+ + Q++ + ++ +E L NQ S R+ +E E + +L+
Sbjct: 630 LKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLM 689
Query: 249 QKIDQLSLIVKENSGASERDMEKKLSQMSARLDKIEEGQKKTFD---GQRTRQEEEKMHG 305
+ I + ++ ++ ++ L +M L+K++E + K + Q E+ K+
Sbjct: 690 KVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVID 749
Query: 306 RITKLELQMNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMK 348
T + + ++ A A E + LRQ LEA K
Sbjct: 750 NFTSQLKATEEKLLDLDALRKASSEGKSE-MKKLRQQLEAAEK 791
Score = 40.4 bits (93), Expect = 0.003
Identities = 77/361 (21%), Positives = 147/361 (40%), Gaps = 67/361 (18%)
Query: 53 RIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNITAIVKQLNRDIEVLQEQIRARDNISY 112
R+K+ V LQ K + FL++ I ++T +Q QE + +
Sbjct: 941 RLKERDVEELQLKLTKANENAS---FLQKSIEDMTVKAEQSQ------QEAAKKHEEEKK 991
Query: 113 GTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHKTTYEGLQHLNKEQQAAKLILE 172
L LE + + + AR + + + +H+ E LQ+L K L E
Sbjct: 992 ELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHE---EILQNLQK----TLLDTE 1044
Query: 173 TKIKDAEGQISQLLNRVD------------------LSISEQSTK-----------LKMS 203
K+K A + S LL ++ + I EQ TK K +
Sbjct: 1045 DKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQT 1104
Query: 204 HRDSNHQLQLLDTKFKGTVEEL--SNQILSARSW----LQQEQERIEKELLQKIDQLSLI 257
+ ++L L VEEL S ++L+ + ++E E +++ QK QLS +
Sbjct: 1105 NAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSAL 1164
Query: 258 VKEN------------SGASERDMEKKLSQMSARLDKIEEGQKKTF-DGQRTRQEEEKMH 304
+EN S + +E++ S ++ +L ++++ + K D + +K
Sbjct: 1165 QEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSI 1224
Query: 305 GRITKLELQMNQNIKEMKAEVNA--GFTAVYESIGSLRQVLEA-KMKLDRDQLQKQIQLM 361
+ L + + +++++ EV G A +S+ S+ Q LE+ K+KL+ ++QL
Sbjct: 1225 SITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLK 1284
Query: 362 Q 362
+
Sbjct: 1285 E 1285
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 48.9 bits (115), Expect = 7e-06
Identities = 80/371 (21%), Positives = 161/371 (43%), Gaps = 55/371 (14%)
Query: 38 LCHEKTTAA----LVEHAFRIKDDIVNSLQKMQNKGGGDRLARL--------FLEEHIRN 85
L +E+ AA ++ + +KDD + L++ +++ L+ ++
Sbjct: 657 LANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQK 716
Query: 86 ITAIV-KQLNRDI-EVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASI 143
+ +V +Q N+D+ E +++ I+ +D LKT+E +GL + + +A
Sbjct: 717 LQTLVSEQPNKDVVEQMEKCIQEKDE-------KLKTVEELLETGLIQVATKEEELNAIR 769
Query: 144 ARLSAEHKTTYEGLQHLNKEQQAAKLILETK--IKDAEGQIS---QLLNRVDLSISEQST 198
S+ K + N + A L+ E K I + +G+I +LL L ++ +
Sbjct: 770 TENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEK 829
Query: 199 KLKMSHRDSNHQLQ-LLDTK------FKGTVEELSNQILSARSWLQQEQERIE--KELLQ 249
+++S +LQ LL K K +EE + + WLQ QE E K +Q
Sbjct: 830 TVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQ 889
Query: 250 KIDQLSLIVKENSGASE--------RDMEKKLSQMSARLDKIEEG-QKKTFDGQRTRQEE 300
++ Q +L KE S AS+ ++ E +L ++ A L + E KT Q + E
Sbjct: 890 EVAQHNL--KEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDEN 947
Query: 301 EKMHGRITKLELQ---------MNQNIKEMKAEVNAGFTAVYESIGSLRQVLEAKMKLDR 351
+ +I +L+ Q ++ + ++ +E + ++ + SL+ +E + K +
Sbjct: 948 KLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNN 1007
Query: 352 DQLQKQIQLMQ 362
D +K + M+
Sbjct: 1008 DLREKNWEAME 1018
Score = 38.1 bits (87), Expect = 0.013
Identities = 55/286 (19%), Positives = 117/286 (40%), Gaps = 35/286 (12%)
Query: 30 VEQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNITAI 89
++ L+D + K L E + + + ++ + +Q+K +E + + A+
Sbjct: 992 LDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDK------VNKTSKERQQQVEAV 1045
Query: 90 VKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAE 149
+ ++ L ++ N+SYG L + C A + S E
Sbjct: 1046 ELEAKEVLKKLFPKVSVPSNLSYG-------------EWLHGFEKKAKECMAGTSG-SEE 1091
Query: 150 HKTTYEGLQHLNKEQQAAKLILET---KIKDAEGQISQLLNRVDLSISEQSTKLKMSHRD 206
K L+H KE +L+ K K + +L ++ S+ ++ K K+ +
Sbjct: 1092 VKV----LEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDE 1147
Query: 207 SNHQLQLLDTKFKGTVEELSNQILSARSW--LQQEQERIEKELLQKIDQLSLIVKENSGA 264
S+ ++ + + F + +EL + L++E+E +E EL + + S V E
Sbjct: 1148 SHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTE---- 1203
Query: 265 SERDMEKKLSQMSARL-DKIEEGQKKTFDGQRTRQEEEKMHGRITK 309
R+++ +L++ +L + E QK D + +Q E + +I K
Sbjct: 1204 -VRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVK 1248
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 48.9 bits (115), Expect = 7e-06
Identities = 66/278 (23%), Positives = 127/278 (45%), Gaps = 51/278 (18%)
Query: 92 QLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHK 151
Q+ R EVLQ + + + + L+ + +G+L+GRVA+ + ARL+
Sbjct: 871 QVTRQDEVLQARAQELQKV--------QELQQQSAREVGELQGRVAQLEEERARLA---- 918
Query: 152 TTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQL 211
EQ A+ L + ++ G+++ ++L +SE ++ + + Q+
Sbjct: 919 -----------EQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVG-EEEECSRQM 966
Query: 212 QLLDTKFKGTVEELSNQILS---ARSWLQQEQERIEKELLQKIDQLSLIVKENSGASERD 268
Q + + ++EL + + AR LQ E+ E ++ + + L L+ +NS S+
Sbjct: 967 QTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSK-- 1024
Query: 269 MEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEMKAEVNAG 328
E+KL + D++ E F Q +EEEK+ + KL L+ I +M+ +
Sbjct: 1025 -ERKLLE-----DRLAE-----FSSQ-AAEEEEKVKS-LNKLRLKYEATIADMEDRLRK- 1070
Query: 329 FTAVYESIGSLRQVLE-AKMKLDRDQLQKQIQLMQKPE 365
E G RQ LE K +LD + + Q Q++++ +
Sbjct: 1071 -----EEKG--RQELEKLKRRLDGESSELQEQMVEQQQ 1101
Score = 42.0 bits (97), Expect = 9e-04
Identities = 55/314 (17%), Positives = 127/314 (40%), Gaps = 45/314 (14%)
Query: 29 LVEQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNITA 88
L + LE+ HE L + + ++ L++ + G RL LE + + A
Sbjct: 1204 LKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRA 1263
Query: 89 IV----------KQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVAR 138
+ +Q R +E+ ++++ R + R + L ++ G +
Sbjct: 1264 ELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNE 1323
Query: 139 CDASIARLSAEHKTTYEGL---QHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISE 195
++ RLS E +T L Q L +E+ AKL L ++++ E + + L +++ E
Sbjct: 1324 AESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE---EE 1380
Query: 196 QSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLS 255
+ + + Q QL + W ++++E E L+ ++
Sbjct: 1381 AAARERAGRELQTAQAQLSE-------------------WRRRQEE--EAGALEAGEE-- 1417
Query: 256 LIVKENSGASERDMEKKLSQMSARLDKIEEG----QKKTFDGQRTRQEEEKMHGRITKLE 311
+ + + ++L++ + +D++E G Q++ D +++ ++ + K +
Sbjct: 1418 --ARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQ 1475
Query: 312 LQMNQNIKEMKAEV 325
+ +Q + E KA V
Sbjct: 1476 RKFDQLLAEEKAAV 1489
Score = 35.8 bits (81), Expect = 0.063
Identities = 53/305 (17%), Positives = 133/305 (43%), Gaps = 23/305 (7%)
Query: 29 LVEQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNITA 88
+V +LE R+ E+ + + R++ I Q+++ + AR L+ A
Sbjct: 948 VVSELEARVGEEEECSRQMQTEKKRLQQHI----QELEAHLEAEEGARQKLQLEKVTTEA 1003
Query: 89 IVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDA---SIAR 145
+K+ D+ +L++Q NS L L + + A + S+ +
Sbjct: 1004 KMKKFEEDLLLLEDQ-----------NSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNK 1052
Query: 146 LSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNR-VDLSISEQSTKLKMSH 204
L +++ T ++ ++++ + LE + +G+ S+L + V+ + + ++
Sbjct: 1053 LRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGR 1112
Query: 205 RDSNHQLQLLDTKFKGTVE-ELSNQILSARSWLQQEQERIEKELLQ--KIDQLSLIVKEN 261
++ Q L + +G +L + A++ L + QE +E E + K ++ + E
Sbjct: 1113 KEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEE 1172
Query: 262 SGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMH-GRITKLELQMNQNIKE 320
A ++E L +A+ + + +++ + ++T +EE ++H + +L + Q + E
Sbjct: 1173 LEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGE 1232
Query: 321 MKAEV 325
+ ++
Sbjct: 1233 LAEQL 1237
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 48.9 bits (115), Expect = 7e-06
Identities = 66/278 (23%), Positives = 127/278 (45%), Gaps = 51/278 (18%)
Query: 92 QLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHK 151
Q+ R EVLQ + + + + L+ + +G+L+GRVA+ + ARL+
Sbjct: 863 QVTRQDEVLQARAQELQKV--------QELQQQSAREVGELQGRVAQLEEERARLA---- 910
Query: 152 TTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQL 211
EQ A+ L + ++ G+++ ++L +SE ++ + + Q+
Sbjct: 911 -----------EQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVG-EEEECSRQM 958
Query: 212 QLLDTKFKGTVEELSNQILS---ARSWLQQEQERIEKELLQKIDQLSLIVKENSGASERD 268
Q + + ++EL + + AR LQ E+ E ++ + + L L+ +NS S+
Sbjct: 959 QTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSK-- 1016
Query: 269 MEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEMKAEVNAG 328
E+KL + D++ E F Q +EEEK+ + KL L+ I +M+ +
Sbjct: 1017 -ERKLLE-----DRLAE-----FSSQ-AAEEEEKVKS-LNKLRLKYEATIADMEDRLRK- 1062
Query: 329 FTAVYESIGSLRQVLE-AKMKLDRDQLQKQIQLMQKPE 365
E G RQ LE K +LD + + Q Q++++ +
Sbjct: 1063 -----EEKG--RQELEKLKRRLDGESSELQEQMVEQQQ 1093
Score = 42.0 bits (97), Expect = 9e-04
Identities = 55/314 (17%), Positives = 127/314 (40%), Gaps = 45/314 (14%)
Query: 29 LVEQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNITA 88
L + LE+ HE L + + ++ L++ + G RL LE + + A
Sbjct: 1196 LKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRA 1255
Query: 89 IV----------KQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVAR 138
+ +Q R +E+ ++++ R + R + L ++ G +
Sbjct: 1256 ELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNE 1315
Query: 139 CDASIARLSAEHKTTYEGL---QHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISE 195
++ RLS E +T L Q L +E+ AKL L ++++ E + + L +++ E
Sbjct: 1316 AESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE---EE 1372
Query: 196 QSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLS 255
+ + + Q QL + W ++++E E L+ ++
Sbjct: 1373 AAARERAGRELQTAQAQLSE-------------------WRRRQEE--EAGALEAGEE-- 1409
Query: 256 LIVKENSGASERDMEKKLSQMSARLDKIEEG----QKKTFDGQRTRQEEEKMHGRITKLE 311
+ + + ++L++ + +D++E G Q++ D +++ ++ + K +
Sbjct: 1410 --ARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQ 1467
Query: 312 LQMNQNIKEMKAEV 325
+ +Q + E KA V
Sbjct: 1468 RKFDQLLAEEKAAV 1481
Score = 35.8 bits (81), Expect = 0.063
Identities = 53/305 (17%), Positives = 133/305 (43%), Gaps = 23/305 (7%)
Query: 29 LVEQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNITA 88
+V +LE R+ E+ + + R++ I Q+++ + AR L+ A
Sbjct: 940 VVSELEARVGEEEECSRQMQTEKKRLQQHI----QELEAHLEAEEGARQKLQLEKVTTEA 995
Query: 89 IVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDA---SIAR 145
+K+ D+ +L++Q NS L L + + A + S+ +
Sbjct: 996 KMKKFEEDLLLLEDQ-----------NSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNK 1044
Query: 146 LSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNR-VDLSISEQSTKLKMSH 204
L +++ T ++ ++++ + LE + +G+ S+L + V+ + + ++
Sbjct: 1045 LRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGR 1104
Query: 205 RDSNHQLQLLDTKFKGTVE-ELSNQILSARSWLQQEQERIEKELLQ--KIDQLSLIVKEN 261
++ Q L + +G +L + A++ L + QE +E E + K ++ + E
Sbjct: 1105 KEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEE 1164
Query: 262 SGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMH-GRITKLELQMNQNIKE 320
A ++E L +A+ + + +++ + ++T +EE ++H + +L + Q + E
Sbjct: 1165 LEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGE 1224
Query: 321 MKAEV 325
+ ++
Sbjct: 1225 LAEQL 1229
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 48.9 bits (115), Expect = 7e-06
Identities = 66/278 (23%), Positives = 127/278 (45%), Gaps = 51/278 (18%)
Query: 92 QLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDASIARLSAEHK 151
Q+ R EVLQ + + + + L+ + +G+L+GRVA+ + ARL+
Sbjct: 904 QVTRQDEVLQARAQELQKV--------QELQQQSAREVGELQGRVAQLEEERARLA---- 951
Query: 152 TTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQL 211
EQ A+ L + ++ G+++ ++L +SE ++ + + Q+
Sbjct: 952 -----------EQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVG-EEEECSRQM 999
Query: 212 QLLDTKFKGTVEELSNQILS---ARSWLQQEQERIEKELLQKIDQLSLIVKENSGASERD 268
Q + + ++EL + + AR LQ E+ E ++ + + L L+ +NS S+
Sbjct: 1000 QTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSK-- 1057
Query: 269 MEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEMKAEVNAG 328
E+KL + D++ E F Q +EEEK+ + KL L+ I +M+ +
Sbjct: 1058 -ERKLLE-----DRLAE-----FSSQ-AAEEEEKVKS-LNKLRLKYEATIADMEDRLRK- 1103
Query: 329 FTAVYESIGSLRQVLE-AKMKLDRDQLQKQIQLMQKPE 365
E G RQ LE K +LD + + Q Q++++ +
Sbjct: 1104 -----EEKG--RQELEKLKRRLDGESSELQEQMVEQQQ 1134
Score = 42.0 bits (97), Expect = 9e-04
Identities = 55/314 (17%), Positives = 127/314 (40%), Gaps = 45/314 (14%)
Query: 29 LVEQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNITA 88
L + LE+ HE L + + ++ L++ + G RL LE + + A
Sbjct: 1237 LKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRA 1296
Query: 89 IV----------KQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVAR 138
+ +Q R +E+ ++++ R + R + L ++ G +
Sbjct: 1297 ELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNE 1356
Query: 139 CDASIARLSAEHKTTYEGL---QHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISE 195
++ RLS E +T L Q L +E+ AKL L ++++ E + + L +++ E
Sbjct: 1357 AESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE---EE 1413
Query: 196 QSTKLKMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLS 255
+ + + Q QL + W ++++E E L+ ++
Sbjct: 1414 AAARERAGRELQTAQAQLSE-------------------WRRRQEE--EAGALEAGEE-- 1450
Query: 256 LIVKENSGASERDMEKKLSQMSARLDKIEEG----QKKTFDGQRTRQEEEKMHGRITKLE 311
+ + + ++L++ + +D++E G Q++ D +++ ++ + K +
Sbjct: 1451 --ARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQ 1508
Query: 312 LQMNQNIKEMKAEV 325
+ +Q + E KA V
Sbjct: 1509 RKFDQLLAEEKAAV 1522
Score = 35.8 bits (81), Expect = 0.063
Identities = 53/305 (17%), Positives = 133/305 (43%), Gaps = 23/305 (7%)
Query: 29 LVEQLEDRILCHEKTTAALVEHAFRIKDDIVNSLQKMQNKGGGDRLARLFLEEHIRNITA 88
+V +LE R+ E+ + + R++ I Q+++ + AR L+ A
Sbjct: 981 VVSELEARVGEEEECSRQMQTEKKRLQQHI----QELEAHLEAEEGARQKLQLEKVTTEA 1036
Query: 89 IVKQLNRDIEVLQEQIRARDNISYGTNSALKTLEMRQLSGLGDLRGRVARCDA---SIAR 145
+K+ D+ +L++Q NS L L + + A + S+ +
Sbjct: 1037 KMKKFEEDLLLLEDQ-----------NSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNK 1085
Query: 146 LSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNR-VDLSISEQSTKLKMSH 204
L +++ T ++ ++++ + LE + +G+ S+L + V+ + + ++
Sbjct: 1086 LRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGR 1145
Query: 205 RDSNHQLQLLDTKFKGTVE-ELSNQILSARSWLQQEQERIEKELLQ--KIDQLSLIVKEN 261
++ Q L + +G +L + A++ L + QE +E E + K ++ + E
Sbjct: 1146 KEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEE 1205
Query: 262 SGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMH-GRITKLELQMNQNIKE 320
A ++E L +A+ + + +++ + ++T +EE ++H + +L + Q + E
Sbjct: 1206 LEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGE 1265
Query: 321 MKAEV 325
+ ++
Sbjct: 1266 LAEQL 1270
>gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens]
Length = 1217
Score = 48.9 bits (115), Expect = 7e-06
Identities = 48/213 (22%), Positives = 106/213 (49%), Gaps = 10/213 (4%)
Query: 141 ASIARLSAEHKTTYEGLQHLNKEQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKL 200
A + LSA+ +T+ E + L QQ A+ K++D E Q+ +L ++ ++ E+ +L
Sbjct: 237 AKLDELSAKRETSGEKSRQLRDAQQDAR----DKMEDIERQVRELKTKIS-AMKEEKEQL 291
Query: 201 KMSHRDSNHQLQLLDTKFKGTVEELSNQILSARSWLQQEQERIEKELLQKIDQLSLIVKE 260
++ Q L+ K K +EL+ + L++ Q+ +EK + +K +L+ +
Sbjct: 292 SAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEK-IEEKQKELAETEPK 350
Query: 261 NSGASERDMEKKLSQMSARLDKIEEGQKKTFDGQRTRQEEEKMHGRITKLELQ-MNQNIK 319
+ E++ E+ +++++ + + K G + +EE+ + K EL+ ++Q I
Sbjct: 351 FNSVKEKE-ERGIARLAQATQERTDLYAKQGRGSQFTSKEER--DKWIKKELKSLDQAIN 407
Query: 320 EMKAEVNAGFTAVYESIGSLRQVLEAKMKLDRD 352
+ K ++ A + ++ + + LE KLD+D
Sbjct: 408 DKKRQIAAIHKDLEDTEANKEKNLEQYNKLDQD 440
Score = 42.0 bits (97), Expect = 9e-04
Identities = 42/190 (22%), Positives = 95/190 (50%), Gaps = 19/190 (10%)
Query: 163 EQQAAKLILETKIKDAEGQISQLLNRVDLSISEQSTKLKMSHRDSNHQLQLLDT---KFK 219
+ + ++L L+ ++ AE ++ +L +++ ++ ++ +Q+Q ++T KFK
Sbjct: 670 DTRKSRLELQKDVRKAEEELGELEAKLNENLRRNIERINNEIDQLMNQMQQIETQQRKFK 729
Query: 220 GTVEELSNQILSARSWLQQEQERIEKELLQKIDQL-SLIVKENSGASERDMEKK------ 272
+ + ILS L++++++ EK + K L SL ++ S R+ K
Sbjct: 730 AS----RDSILSEMKMLKEKRQQSEKTFMPKQRSLQSLEASLHAMESTRESLKAELGTDL 785
Query: 273 LSQMSA----RLDKI-EEGQKKTFDGQRTRQEEEKMHGRITKLELQMNQNIKEMKAEVNA 327
LSQ+S R+D + +E ++ + ++ E K+ G IT++E +N+N+++ +V
Sbjct: 786 LSQLSLEDQKRVDALNDEIRQLQQENRQLLNERIKLEGIITRVETYLNENLRKRLDQVEQ 845
Query: 328 GFTAVYESIG 337
+ E+ G
Sbjct: 846 ELNELRETEG 855
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.128 0.336
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,188,051
Number of Sequences: 37866
Number of extensions: 435027
Number of successful extensions: 3496
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 574
Number of HSP's that attempted gapping in prelim test: 2494
Number of HSP's gapped (non-prelim): 1242
length of query: 368
length of database: 18,247,518
effective HSP length: 104
effective length of query: 264
effective length of database: 14,309,454
effective search space: 3777695856
effective search space used: 3777695856
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.