Guide to the Human Genome
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Search of human proteins with 148613856

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
         (731 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]        1500   0.0  
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]         1491   0.0  
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]    807   0.0  
gi|13787204 DEAD box polypeptide 17 isoform 2 [Homo sapiens]          383   e-106
gi|148613858 DEAD box polypeptide 17 isoform 4 [Homo sapiens]         374   e-103
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]            373   e-103
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]            373   e-103
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...   363   e-100
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...   335   7e-92
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi...   334   2e-91
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo...   334   2e-91
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ...   325   9e-89
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [...   325   9e-89
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...   294   2e-79
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ...   283   3e-76
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [...   283   3e-76
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ...   283   3e-76
gi|21071032 DEAD-box protein abstrakt [Homo sapiens]                  267   2e-71
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap...   242   1e-63
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...   222   8e-58
gi|13129006 nucleolar protein GU2 [Homo sapiens]                      206   6e-53
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi...   205   1e-52
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...   204   3e-52
gi|7661920 eukaryotic translation initiation factor 4A, isoform ...   201   3e-51
gi|4503529 eukaryotic translation initiation factor 4A isoform 1...   195   1e-49
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...   191   2e-48
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ...   190   5e-48
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ...   190   5e-48
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1...   190   5e-48
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...   189   8e-48

>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score = 1500 bits (3883), Expect = 0.0
 Identities = 731/731 (100%), Positives = 731/731 (100%)

Query: 1   MPTGFVAPILCVLLPSPTREAATVASATGDSASERESAAPAAAPTAEAPPPSVVTRPEPQ 60
           MPTGFVAPILCVLLPSPTREAATVASATGDSASERESAAPAAAPTAEAPPPSVVTRPEPQ
Sbjct: 1   MPTGFVAPILCVLLPSPTREAATVASATGDSASERESAAPAAAPTAEAPPPSVVTRPEPQ 60

Query: 61  ALPSPAIRAPLPDLYPFGTMRGGGFGDRDRDRDRGGFGARGGGGLPPKKFGNPGERLRKK 120
           ALPSPAIRAPLPDLYPFGTMRGGGFGDRDRDRDRGGFGARGGGGLPPKKFGNPGERLRKK
Sbjct: 61  ALPSPAIRAPLPDLYPFGTMRGGGFGDRDRDRDRGGFGARGGGGLPPKKFGNPGERLRKK 120

Query: 121 KWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQ 180
           KWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQ
Sbjct: 121 KWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQ 180

Query: 181 YVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLE 240
           YVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLE
Sbjct: 181 YVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLE 240

Query: 241 RGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIA 300
           RGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIA
Sbjct: 241 RGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIA 300

Query: 301 TPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWP 360
           TPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWP
Sbjct: 301 TPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWP 360

Query: 361 KEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENK 420
           KEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENK
Sbjct: 361 KEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENK 420

Query: 421 TIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASR 480
           TIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASR
Sbjct: 421 TIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASR 480

Query: 481 GLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEA 540
           GLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEA
Sbjct: 481 GLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEA 540

Query: 541 NQAINPKLMQLVDHRGGGGGGGKGGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRD 600
           NQAINPKLMQLVDHRGGGGGGGKGGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRD
Sbjct: 541 NQAINPKLMQLVDHRGGGGGGGKGGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRD 600

Query: 601 SASYRDRSETDRAGYANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAG 660
           SASYRDRSETDRAGYANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAG
Sbjct: 601 SASYRDRSETDRAGYANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAG 660

Query: 661 TYGASSTTSTGRSSQSSSQQFSGIGRSGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYP 720
           TYGASSTTSTGRSSQSSSQQFSGIGRSGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYP
Sbjct: 661 TYGASSTTSTGRSSQSSSQQFSGIGRSGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYP 720

Query: 721 PPPPPPPPSRK 731
           PPPPPPPPSRK
Sbjct: 721 PPPPPPPPSRK 731


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score = 1491 bits (3859), Expect = 0.0
 Identities = 729/731 (99%), Positives = 729/731 (99%), Gaps = 2/731 (0%)

Query: 1   MPTGFVAPILCVLLPSPTREAATVASATGDSASERESAAPAAAPTAEAPPPSVVTRPEPQ 60
           MPTGFVAPILCVLLPSPTREAATVASATGDSASERESAAPAAAPTAEAPPPSVVTRPEPQ
Sbjct: 1   MPTGFVAPILCVLLPSPTREAATVASATGDSASERESAAPAAAPTAEAPPPSVVTRPEPQ 60

Query: 61  ALPSPAIRAPLPDLYPFGTMRGGGFGDRDRDRDRGGFGARGGGGLPPKKFGNPGERLRKK 120
           ALPSPAIRAPLPDLYPFGTMRGGGFGDRDRDRDRGGFGARGGGGLPPKKFGNPGERLRKK
Sbjct: 61  ALPSPAIRAPLPDLYPFGTMRGGGFGDRDRDRDRGGFGARGGGGLPPKKFGNPGERLRKK 120

Query: 121 KWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQ 180
           KWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQ
Sbjct: 121 KWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQ 180

Query: 181 YVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLE 240
           YVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLE
Sbjct: 181 YVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLE 240

Query: 241 RGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIA 300
           RGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIA
Sbjct: 241 RGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIA 300

Query: 301 TPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWP 360
           TPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWP
Sbjct: 301 TPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWP 360

Query: 361 KEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENK 420
           KEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENK
Sbjct: 361 KEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENK 420

Query: 421 TIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASR 480
           TIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASR
Sbjct: 421 TIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASR 480

Query: 481 GLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEA 540
           GLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEA
Sbjct: 481 GLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEA 540

Query: 541 NQAINPKLMQLVDHRGGGGGGGKGGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRD 600
           NQAINPKLMQLVDHRGGGGGG  GGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRD
Sbjct: 541 NQAINPKLMQLVDHRGGGGGG--GGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRD 598

Query: 601 SASYRDRSETDRAGYANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAG 660
           SASYRDRSETDRAGYANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAG
Sbjct: 599 SASYRDRSETDRAGYANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAG 658

Query: 661 TYGASSTTSTGRSSQSSSQQFSGIGRSGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYP 720
           TYGASSTTSTGRSSQSSSQQFSGIGRSGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYP
Sbjct: 659 TYGASSTTSTGRSSQSSSQQFSGIGRSGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYP 718

Query: 721 PPPPPPPPSRK 731
           PPPPPPPPSRK
Sbjct: 719 PPPPPPPPSRK 729


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score =  807 bits (2085), Expect = 0.0
 Identities = 435/645 (67%), Positives = 482/645 (74%), Gaps = 45/645 (6%)

Query: 83  GGFGDRDRDRDRG----GFGARGGGGLPPKKFGNPGERLRKKKWDLSELPKFEKNFYVEH 138
           G   DRDR RDRG     FG    G L  KKFGNPGE+L KKKW+L ELPKFEKNFY EH
Sbjct: 3   GYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQEH 62

Query: 139 PEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQ 198
           P++AR T  EV+  RR KEITVRG + CPKPV  F+ ANFP  VMDV+  Q+FTEPT IQ
Sbjct: 63  PDLARRTAQEVETYRRSKEITVRGHN-CPKPVLNFYEANFPANVMDVIARQNFTEPTAIQ 121

Query: 199 CQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQ 258
            QG+P+ALSG DMVG+AQTGSGKTL+YLLPAIVHINHQP+LERGDGPICLVLAPTRELAQ
Sbjct: 122 AQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQ 181

Query: 259 QVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRR 318
           QVQQVA +Y +  RLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE GKTNLRR
Sbjct: 182 QVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRR 241

Query: 319 CTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQIN 378
            TYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFL+DY  IN
Sbjct: 242 TTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHIN 301

Query: 379 VGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRM 438
           +G LELSANHNILQIVDVC + EKD KLI+LMEEIM+EKENKTI+FVETKRRCD+LTR+M
Sbjct: 302 IGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKM 361

Query: 439 RRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNS 498
           RRDGWPAM IHGDKSQ ERDWVLNEF+ GKAPILIATDVASRGLDVEDVKFVINYDYPNS
Sbjct: 362 RRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNS 421

Query: 499 SEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDHRGGG 558
           SEDY+HRIGRTARST  GTAYTFFTP N+KQ  +LI VL EANQAINPKL+QLV+ RG G
Sbjct: 422 SEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGSG 481

Query: 559 GGGGKGGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGYANG 618
              G+GG               M  D  DR   G + G      ++RDR   DR      
Sbjct: 482 RSRGRGG---------------MKDDRRDRYSAGKRGGFN----TFRDRENYDR------ 516

Query: 619 SGYGS-PNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAG---TYGASSTTSTGRSS 674
            GY S     FGA+        G Y AA Y   S+ +    AG   ++   + T T ++ 
Sbjct: 517 -GYSSLLKRDFGAKT-----QNGVYSAANYTNGSFGSNFVSAGIQTSFRTGNPTGTYQNG 570

Query: 675 QSSSQQFSGIGRSGQQPQPLMSQQ-FAQP-PGATNMIGYMGQTAY 717
             S+QQ+   G +       M+QQ +A P   A  MIGY   T Y
Sbjct: 571 YDSTQQY---GSNVPNMHNGMNQQAYAYPATAAAPMIGYPMPTGY 612


>gi|13787204 DEAD box polypeptide 17 isoform 2 [Homo sapiens]
          Length = 183

 Score =  383 bits (983), Expect = e-106
 Identities = 183/183 (100%), Positives = 183/183 (100%)

Query: 549 MQLVDHRGGGGGGGKGGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRS 608
           MQLVDHRGGGGGGGKGGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRS
Sbjct: 1   MQLVDHRGGGGGGGKGGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRS 60

Query: 609 ETDRAGYANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAGTYGASSTT 668
           ETDRAGYANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAGTYGASSTT
Sbjct: 61  ETDRAGYANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAGTYGASSTT 120

Query: 669 STGRSSQSSSQQFSGIGRSGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYPPPPPPPPP 728
           STGRSSQSSSQQFSGIGRSGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYPPPPPPPPP
Sbjct: 121 STGRSSQSSSQQFSGIGRSGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYPPPPPPPPP 180

Query: 729 SRK 731
           SRK
Sbjct: 181 SRK 183


>gi|148613858 DEAD box polypeptide 17 isoform 4 [Homo sapiens]
          Length = 181

 Score =  374 bits (959), Expect = e-103
 Identities = 181/183 (98%), Positives = 181/183 (98%), Gaps = 2/183 (1%)

Query: 549 MQLVDHRGGGGGGGKGGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRS 608
           MQLVDHRGGGGGGG  GRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRS
Sbjct: 1   MQLVDHRGGGGGGG--GRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRS 58

Query: 609 ETDRAGYANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAGTYGASSTT 668
           ETDRAGYANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAGTYGASSTT
Sbjct: 59  ETDRAGYANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAGTYGASSTT 118

Query: 669 STGRSSQSSSQQFSGIGRSGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYPPPPPPPPP 728
           STGRSSQSSSQQFSGIGRSGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYPPPPPPPPP
Sbjct: 119 STGRSSQSSSQQFSGIGRSGQQPQPLMSQQFAQPPGATNMIGYMGQTAYQYPPPPPPPPP 178

Query: 729 SRK 731
           SRK
Sbjct: 179 SRK 181


>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  373 bits (957), Expect = e-103
 Identities = 224/620 (36%), Positives = 339/620 (54%), Gaps = 42/620 (6%)

Query: 88  RDRDRDRGGFGARGGGGLPPKKFGNPGERLRKKKWDLSELPKFEKNFYVEHPEVARLTPY 147
           ++ + D   + + G    P KK  +P   +   + D    P FEKNFY EH E+  LTP 
Sbjct: 174 QEEEEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDY---PPFEKNFYNEHEEITNLTPQ 230

Query: 148 EVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALS 207
           ++ +LR K  + V G    P+P  +F H  F + +M  +    +T+PTPIQCQG P+ALS
Sbjct: 231 QLIDLRHKLNLRVSGA-APPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALS 289

Query: 208 GRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDY 267
           GRDM+GIA+TGSGKT A++ P ++HI  Q  LE GDGPI +++ PTREL QQ+      +
Sbjct: 290 GRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRF 349

Query: 268 GKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEA 327
           GK   L+S  +YGG     Q + L+ G EI + TPGRLID ++   TNL+R +YLV DEA
Sbjct: 350 GKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEA 409

Query: 328 DRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSAN 387
           DRM DMGFE Q+R I   +RPDRQTL++SAT+ K++ +LA D L D  ++  G++   AN
Sbjct: 410 DRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIG-EAN 468

Query: 388 HNILQIVDVCMES-EKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAM 446
            ++ QIV++      K + L + + E  +      ++FV  K   ++L   ++++G    
Sbjct: 469 EDVTQIVEILHSGPSKWNWLTRRLVEFTS--SGSVLLFVTKKANAEELANNLKQEGHNLG 526

Query: 447 CIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRI 506
            +HGD  Q ER+ V+++F+    P+L+ATDVA+RGLD+  +K VINYD     + + HRI
Sbjct: 527 LLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRI 586

Query: 507 GRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLV-------DHRGGGG 559
           GRT R+  KG AYT  TP +   A +L++ LE ANQ ++ +L+ L          R  GG
Sbjct: 587 GRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGG 646

Query: 560 GGGK----GGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGY 615
            G K    GG   YR      + N+   D  +  +    +  +  + +  DR    +A +
Sbjct: 647 KGKKLNIGGGGLGYRERPGLGSENM---DRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAF 703

Query: 616 ANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAGTYGASSTTST--GRS 673
                     S + +     +      G++A G S +T+    AG+  +  T S   G +
Sbjct: 704 ---------QSQYKSHFVAASLSNQKAGSSAAGASGWTS----AGSLNSVPTNSAQQGHN 750

Query: 674 S-----QSSSQQFSGIGRSG 688
           S      S+++   G G +G
Sbjct: 751 SPDSPVTSAAKGIPGFGNTG 770


>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  373 bits (957), Expect = e-103
 Identities = 224/620 (36%), Positives = 339/620 (54%), Gaps = 42/620 (6%)

Query: 88  RDRDRDRGGFGARGGGGLPPKKFGNPGERLRKKKWDLSELPKFEKNFYVEHPEVARLTPY 147
           ++ + D   + + G    P KK  +P   +   + D    P FEKNFY EH E+  LTP 
Sbjct: 174 QEEEEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDY---PPFEKNFYNEHEEITNLTPQ 230

Query: 148 EVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALS 207
           ++ +LR K  + V G    P+P  +F H  F + +M  +    +T+PTPIQCQG P+ALS
Sbjct: 231 QLIDLRHKLNLRVSGA-APPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALS 289

Query: 208 GRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDY 267
           GRDM+GIA+TGSGKT A++ P ++HI  Q  LE GDGPI +++ PTREL QQ+      +
Sbjct: 290 GRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRF 349

Query: 268 GKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEA 327
           GK   L+S  +YGG     Q + L+ G EI + TPGRLID ++   TNL+R +YLV DEA
Sbjct: 350 GKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEA 409

Query: 328 DRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSAN 387
           DRM DMGFE Q+R I   +RPDRQTL++SAT+ K++ +LA D L D  ++  G++   AN
Sbjct: 410 DRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIG-EAN 468

Query: 388 HNILQIVDVCMES-EKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAM 446
            ++ QIV++      K + L + + E  +      ++FV  K   ++L   ++++G    
Sbjct: 469 EDVTQIVEILHSGPSKWNWLTRRLVEFTS--SGSVLLFVTKKANAEELANNLKQEGHNLG 526

Query: 447 CIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRI 506
            +HGD  Q ER+ V+++F+    P+L+ATDVA+RGLD+  +K VINYD     + + HRI
Sbjct: 527 LLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRI 586

Query: 507 GRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLV-------DHRGGGG 559
           GRT R+  KG AYT  TP +   A +L++ LE ANQ ++ +L+ L          R  GG
Sbjct: 587 GRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGG 646

Query: 560 GGGK----GGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGY 615
            G K    GG   YR      + N+   D  +  +    +  +  + +  DR    +A +
Sbjct: 647 KGKKLNIGGGGLGYRERPGLGSENM---DRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAF 703

Query: 616 ANGSGYGSPNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAGTYGASSTTST--GRS 673
                     S + +     +      G++A G S +T+    AG+  +  T S   G +
Sbjct: 704 ---------QSQYKSHFVAASLSNQKAGSSAAGASGWTS----AGSLNSVPTNSAQQGHN 750

Query: 674 S-----QSSSQQFSGIGRSG 688
           S      S+++   G G +G
Sbjct: 751 SPDSPVTSAAKGIPGFGNTG 770


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score =  363 bits (932), Expect = e-100
 Identities = 194/430 (45%), Positives = 275/430 (63%), Gaps = 8/430 (1%)

Query: 126 ELPKFEKNFYVEHPEVARLTPYEVDELRRKKE-ITVRGGDVCPKPVFAFHHANFPQYVMD 184
           E   F KNFYVE PE+A+++  EV+  R + E ITV+G   CPKP+ ++        +++
Sbjct: 327 EYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKG-CPKPIKSWVQCGISMKILN 385

Query: 185 VLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDG 244
            L    + +PTPIQ Q  P  +SGRD++GIA+TGSGKT+A+LLP   HI  Q  LE G+G
Sbjct: 386 SLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEG 445

Query: 245 PICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGR 304
           PI +++ PTRELA Q+ +    + K   L+  C+YGG     QI +L+RG EI + TPGR
Sbjct: 446 PIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGR 505

Query: 305 LIDFL--ESGK-TNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPK 361
           +ID L   SG+ TNLRR TY+VLDEADRM DMGFEPQ+ +IVD +RPDRQT+M+SAT+P+
Sbjct: 506 MIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPR 565

Query: 362 EVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKT 421
            +  LA   L    ++ VG   +  + ++ Q V V  E +K  KL++L+     ++    
Sbjct: 566 AMEALARRILSKPIEVQVGGRSVVCS-DVEQQVIVIEEEKKFLKLLELLGHY--QESGSV 622

Query: 422 IIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRG 481
           IIFV+ +   D L + + R  +P M +HG   Q +RD ++N+F++G   +L+AT VA+RG
Sbjct: 623 IIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARG 682

Query: 482 LDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEAN 541
           LDV+ +  V+NY  PN  EDYVHR GRT R+ NKG AYTF T    + A ++IK LE + 
Sbjct: 683 LDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSG 742

Query: 542 QAINPKLMQL 551
            A+ P L +L
Sbjct: 743 TAVPPDLEKL 752


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score =  335 bits (860), Expect = 7e-92
 Identities = 193/455 (42%), Positives = 275/455 (60%), Gaps = 27/455 (5%)

Query: 114 GERLRKKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDV-------C 166
           G + +K KW  ++LP  +KNFY E    + ++  E D   RK+   +   D+        
Sbjct: 180 GLKWQKTKW--ADLPPIKKNFYKESTATSAMSKVEADSW-RKENFNITWDDLKDGEKRPI 236

Query: 167 PKPVFAFHHA--NFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLA 224
           P P   F  A   +P+ VM+ +    F +PTPIQ Q +P+ L G D++G+AQTG+GKTL 
Sbjct: 237 PNPTCTFDDAFQCYPE-VMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLC 295

Query: 225 YLLPAIVHINHQPYLE-RGDGPICLVLAPTRELAQQVQQVADDYGKCSR-----LKSTCI 278
           YL+P  +H+  QP L+ + + P  LVL PTRELA QV+      G+C +     L+S C+
Sbjct: 296 YLMPGFIHLVLQPSLKGQRNRPGMLVLTPTRELALQVE------GECCKYSYKGLRSVCV 349

Query: 279 YGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQ 338
           YGG  +  QI +L++GV+I IATPGRL D   S   NL+  TYLVLDEAD+MLDMGFEPQ
Sbjct: 350 YGGGNRDEQIEELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQ 409

Query: 339 IRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCM 398
           I KI+  +RPDRQT+M SATWP  V +LA+ +L++   + VG L+L A  ++ Q + V  
Sbjct: 410 IMKILLDVRPDRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTT 469

Query: 399 ESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERD 458
           E EK   +   ++ +     +K I+FV  K   D L+  +         +HGD+ Q +R+
Sbjct: 470 EEEKWSHMQTFLQSM--SSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDRE 527

Query: 459 WVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTA 518
             L  F++GK  ILIATD+ASRGLDV DV  V N+D+P + E+YVHRIGRT R+   G +
Sbjct: 528 KALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVS 587

Query: 519 YTFFTPGNLKQARELIKVLEEANQAINPKLMQLVD 553
            T  T  + + A ELI +LE ANQ+I  +L+ + +
Sbjct: 588 ITTLTRNDWRVASELINILERANQSIPEELVSMAE 622


>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
           sapiens]
          Length = 631

 Score =  334 bits (857), Expect = 2e-91
 Identities = 194/444 (43%), Positives = 272/444 (61%), Gaps = 15/444 (3%)

Query: 119 KKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKK-EIT---VRGGD--VCPKPVFA 172
           K+KW  ++LP  +KNFY+E    + ++  +V   R++   IT   ++ G+  + PKP   
Sbjct: 165 KRKW--ADLPPVKKNFYIESKATSCMSEMQVINWRKENFNITCDDLKSGEKRLIPKPTCR 222

Query: 173 FHHANFPQY--VMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAI 230
           F  A F QY  ++  ++     +PTPIQ Q +P+ L G D++ +AQTG+GKTL+YL+P  
Sbjct: 223 FKDA-FQQYPDLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGF 281

Query: 231 VHINHQPYL-ERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIR 289
           +H++ QP   E+ +GP  LVL PTRELA  V+     Y     LKS CIYGG  +  QI 
Sbjct: 282 IHLDSQPISREQRNGPGMLVLTPTRELALHVEAECSKYSY-KGLKSICIYGGRNRNGQIE 340

Query: 290 DLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPD 349
           D+ +GV+I IATPGRL D   +   NLR  TYLV+DEAD+MLDM FEPQIRKI+  +RPD
Sbjct: 341 DISKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPD 400

Query: 350 RQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQL 409
           RQT+M SATWP  VRQLA  +L+D   + VGNL L A + + Q + V  E EK   L Q 
Sbjct: 401 RQTVMTSATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEK-RALTQE 459

Query: 410 MEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKA 469
             E M+  + K I+FV  K   DDL+      G  A  +HG+  Q +++  + +F+SG  
Sbjct: 460 FVENMSPND-KVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNI 518

Query: 470 PILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQ 529
            ILI TD+ SRGLD+ DV  V NYD+P + + YVHR+G   R+   GT+ T  T  + K 
Sbjct: 519 KILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKM 578

Query: 530 ARELIKVLEEANQAINPKLMQLVD 553
           A ELIK+L+ ANQ++   L+ + +
Sbjct: 579 AGELIKILDRANQSVPEDLVVMAE 602


>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
           sapiens]
          Length = 662

 Score =  334 bits (856), Expect = 2e-91
 Identities = 205/511 (40%), Positives = 286/511 (55%), Gaps = 45/511 (8%)

Query: 163 GDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKT 222
           G+ CP  + +F      + +M  +    +T PTP+Q    P+    RD++  AQTGSGKT
Sbjct: 172 GNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKT 231

Query: 223 LAYLLPAIVHI-------------NHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGK 269
            A+LLP +  I              +  Y  R   PI LVLAPTRELA Q+ + A  +  
Sbjct: 232 AAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSY 291

Query: 270 CSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADR 329
            SR++   +YGGA  G QIRDLERG  + +ATPGRL+D +E GK  L  C YLVLDEADR
Sbjct: 292 RSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADR 351

Query: 330 MLDMGFEPQIRKIVDQI----RPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELS 385
           MLDMGFEPQIR+IV+Q     +  R T+M+SAT+PKE++ LA DFL +Y  + VG +  S
Sbjct: 352 MLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVG-S 410

Query: 386 ANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPA 445
            + NI Q V    ES+K   L+ L+      K++ T++FVETK+  D L   +  +G+  
Sbjct: 411 TSENITQKVVWVEESDKRSFLLDLLNA--TGKDSLTLVFVETKKGADSLEDFLYHEGYAC 468

Query: 446 MCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHR 505
             IHGD+SQ +R+  L++FRSGK+PIL+AT VA+RGLD+ +VK VIN+D P+  E+YVHR
Sbjct: 469 TSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHR 528

Query: 506 IGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLV-DHRGGGGGGGKG 564
           IGRT R  N G A +FF   N+   ++L+ +L EA Q +   L  +  +H   G   G+ 
Sbjct: 529 IGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRS 588

Query: 565 GRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGYANGSGYGSP 624
             SR+     A +                +  G   S+    R+ + R+G   G G+GS 
Sbjct: 589 KSSRFSGGFGARDYR--------------QSSGASSSSFSSSRASSSRSG---GGGHGSS 631

Query: 625 NSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQ 655
               G   G      G Y +  YG  +Y +Q
Sbjct: 632 RGFGGGGYG------GFYNSDGYG-GNYNSQ 655


>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  325 bits (833), Expect = 9e-89
 Identities = 200/511 (39%), Positives = 282/511 (55%), Gaps = 45/511 (8%)

Query: 163 GDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKT 222
           G  CP  +  F   +  + +M  +    +T PTP+Q    P+    RD++  AQTGSGKT
Sbjct: 170 GSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKT 229

Query: 223 LAYLLPAIVHI-------------NHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGK 269
            A+LLP +  I              +  Y  R   PI LVLAPTRELA Q+ + A  +  
Sbjct: 230 AAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSY 289

Query: 270 CSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADR 329
            SR++   +YGGA  G QIRDLERG  + +ATPGRL+D +E GK  L  C YLVLDEADR
Sbjct: 290 RSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADR 349

Query: 330 MLDMGFEPQIRKIVDQ----IRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELS 385
           MLDMGFEPQIR+IV+Q     +  R T+M+SAT+PKE++ LA DFL +Y  + VG +  S
Sbjct: 350 MLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVG-S 408

Query: 386 ANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPA 445
            + NI Q V    + +K   L+ ++       ++ T++FVETK+  D L   +  +G+  
Sbjct: 409 TSENITQKVVWVEDLDKRSFLLDILG--ATGSDSLTLVFVETKKGADSLEDFLYHEGYAC 466

Query: 446 MCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHR 505
             IHGD+SQ +R+  L++FRSGK+PIL+AT VA+RGLD+ +V+ VIN+D P+  E+YVHR
Sbjct: 467 TSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHR 526

Query: 506 IGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLV-DHRGGGGGGGKG 564
           IGRT R  N G A +FF   N+   ++L+ +L EA Q +   L  +  +H   GG  G+ 
Sbjct: 527 IGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRS 586

Query: 565 GRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGYANGSGYGSP 624
             +R+     A +                +  G   S     R  + R+G   G GYG+ 
Sbjct: 587 KSNRFSGGFGARDYR--------------QSSGSSSSGFGASRGSSSRSG---GGGYGNS 629

Query: 625 NSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQ 655
               G   G      G Y +  YG  +Y +Q
Sbjct: 630 RGFGGGGYG------GFYNSDGYG-GNYNSQ 653


>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  325 bits (833), Expect = 9e-89
 Identities = 200/511 (39%), Positives = 282/511 (55%), Gaps = 45/511 (8%)

Query: 163 GDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKT 222
           G  CP  +  F   +  + +M  +    +T PTP+Q    P+    RD++  AQTGSGKT
Sbjct: 170 GSNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKT 229

Query: 223 LAYLLPAIVHI-------------NHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGK 269
            A+LLP +  I              +  Y  R   PI LVLAPTRELA Q+ + A  +  
Sbjct: 230 AAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSY 289

Query: 270 CSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADR 329
            SR++   +YGGA  G QIRDLERG  + +ATPGRL+D +E GK  L  C YLVLDEADR
Sbjct: 290 RSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADR 349

Query: 330 MLDMGFEPQIRKIVDQ----IRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELS 385
           MLDMGFEPQIR+IV+Q     +  R T+M+SAT+PKE++ LA DFL +Y  + VG +  S
Sbjct: 350 MLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVG-S 408

Query: 386 ANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPA 445
            + NI Q V    + +K   L+ ++       ++ T++FVETK+  D L   +  +G+  
Sbjct: 409 TSENITQKVVWVEDLDKRSFLLDILG--ATGSDSLTLVFVETKKGADSLEDFLYHEGYAC 466

Query: 446 MCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHR 505
             IHGD+SQ +R+  L++FRSGK+PIL+AT VA+RGLD+ +V+ VIN+D P+  E+YVHR
Sbjct: 467 TSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHR 526

Query: 506 IGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLV-DHRGGGGGGGKG 564
           IGRT R  N G A +FF   N+   ++L+ +L EA Q +   L  +  +H   GG  G+ 
Sbjct: 527 IGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRS 586

Query: 565 GRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGYANGSGYGSP 624
             +R+     A +                +  G   S     R  + R+G   G GYG+ 
Sbjct: 587 KSNRFSGGFGARDYR--------------QSSGSSSSGFGASRGSSSRSG---GGGYGNS 629

Query: 625 NSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQ 655
               G   G      G Y +  YG  +Y +Q
Sbjct: 630 RGFGGGGYG------GFYNSDGYG-GNYNSQ 653


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score =  294 bits (752), Expect = 2e-79
 Identities = 176/482 (36%), Positives = 271/482 (56%), Gaps = 46/482 (9%)

Query: 117 LRKKKWDLSELPKFEKNFYVEHPEVARLTPYEVDEL--------RRKKEITVRGGDVCPK 168
           L +K+ + + L K  K    +  +    +  ++DE+        R    IT +GG + P 
Sbjct: 330 LEEKEQEEARLRKLRKKEAKQRWDDRHWSQKKLDEMTDRDWRIFREDYSITTKGGKI-PN 388

Query: 169 PVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLP 228
           P+ ++  ++ P ++++V+    + EPTPIQ Q  P+ L  RD++G+A+TGSGKT A+L+P
Sbjct: 389 PIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIP 448

Query: 229 AIVHINHQPYLER----GDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPK 284
            +V I   P ++R      GP  ++LAPTRELAQQ+++    +GK   +++  + GG  +
Sbjct: 449 LLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISR 508

Query: 285 GPQIRDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVD 344
             Q   L  G EI IATPGRLID LE+    L RCTY+VLDEADRM+DMGFEP ++KI++
Sbjct: 509 EDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILE 568

Query: 345 QI-----RPD---------------------RQTLMWSATWPKEVRQLAEDFLRDYTQIN 378
            +     +PD                     RQT+M++AT P  V +LA  +LR    + 
Sbjct: 569 HMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVY 628

Query: 379 VGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRM 438
           +G+     +  + Q V +  ESEK  KL+ ++E+     +   IIFV  K+ CD L + +
Sbjct: 629 IGSAG-KPHERVEQKVFLMSESEKRKKLLAILEQGF---DPPIIIFVNQKKGCDVLAKSL 684

Query: 439 RRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNS 498
            + G+ A  +HG K Q +R++ L+  ++G   IL+ATDVA RG+D++DV  V+NYD   +
Sbjct: 685 EKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKN 744

Query: 499 SEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIK-VLEEANQAINPKLMQLVD--HR 555
            EDY+HRIGRT R+   G A TF T  +     EL + +LE    +  P+L    D  H+
Sbjct: 745 IEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAILESPVSSCPPELANHPDAQHK 804

Query: 556 GG 557
            G
Sbjct: 805 PG 806


>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
           [Homo sapiens]
          Length = 724

 Score =  283 bits (725), Expect = 3e-76
 Identities = 180/491 (36%), Positives = 277/491 (56%), Gaps = 28/491 (5%)

Query: 77  FGTMRG--GGFGDRDRDRDRGGFGARGGG--GLPPKKFGNPGERLRKKKWDLSELPKFE- 131
           FG+ R    G G+ D  + R G G+  GG  GL  +     G+   K + +  E    + 
Sbjct: 182 FGSRRPVLSGTGNGDTSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQG 241

Query: 132 -KNFYVEHP----EVARLTPYEVDELRRKKE---ITVRGGDVCPKPVFAFHHANFPQYVM 183
            K  Y+  P    E +    Y+      K +   + V G D  P  +  F  AN  Q + 
Sbjct: 242 PKVTYIPPPPPEDEDSIFAHYQTGINFDKYDTILVEVSGHDA-PPAILTFEEANLCQTLN 300

Query: 184 DVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPY----L 239
           + +    +T+ TP+Q    P+ L+GRD++  AQTGSGKT A+LLP + H+ H        
Sbjct: 301 NNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRF 360

Query: 240 ERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICI 299
           +    P C+++APTREL  Q+   A  +   + +++  IYGG   G  IR + +G  I  
Sbjct: 361 KELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 420

Query: 300 ATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVD----QIRPDRQTLMW 355
           ATPGRL+D +   K  L++  YLVLDEADRMLDMGF P+++K++       +  RQTLM+
Sbjct: 421 ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 480

Query: 356 SATWPKEVRQLAEDFLR-DYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIM 414
           SAT+P+E+++LA +FL+ +Y  + VG +   A  ++ Q V    +  K  KL++++  I 
Sbjct: 481 SATFPEEIQRLAAEFLKSNYLFVAVGQVG-GACRDVQQTVLQVGQFSKREKLVEILRNIG 539

Query: 415 AEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIA 474
            E+   T++FVETK++ D +   + ++      IHGD+ Q ER+  L +FR GK P+L+A
Sbjct: 540 DER---TMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVA 596

Query: 475 TDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFF-TPGNLKQAREL 533
           T VA+RGLD+E+V+ VIN+D P++ ++YVHRIGRT R  N G A +FF    +   A+ L
Sbjct: 597 TSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPL 656

Query: 534 IKVLEEANQAI 544
           +KVL +A Q +
Sbjct: 657 VKVLTDAQQDV 667


>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
           [Homo sapiens]
          Length = 724

 Score =  283 bits (725), Expect = 3e-76
 Identities = 180/491 (36%), Positives = 277/491 (56%), Gaps = 28/491 (5%)

Query: 77  FGTMRG--GGFGDRDRDRDRGGFGARGGG--GLPPKKFGNPGERLRKKKWDLSELPKFE- 131
           FG+ R    G G+ D  + R G G+  GG  GL  +     G+   K + +  E    + 
Sbjct: 182 FGSRRPVLSGTGNGDTSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQG 241

Query: 132 -KNFYVEHP----EVARLTPYEVDELRRKKE---ITVRGGDVCPKPVFAFHHANFPQYVM 183
            K  Y+  P    E +    Y+      K +   + V G D  P  +  F  AN  Q + 
Sbjct: 242 PKVTYIPPPPPEDEDSIFAHYQTGINFDKYDTILVEVSGHDA-PPAILTFEEANLCQTLN 300

Query: 184 DVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPY----L 239
           + +    +T+ TP+Q    P+ L+GRD++  AQTGSGKT A+LLP + H+ H        
Sbjct: 301 NNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRF 360

Query: 240 ERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICI 299
           +    P C+++APTREL  Q+   A  +   + +++  IYGG   G  IR + +G  I  
Sbjct: 361 KELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 420

Query: 300 ATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVD----QIRPDRQTLMW 355
           ATPGRL+D +   K  L++  YLVLDEADRMLDMGF P+++K++       +  RQTLM+
Sbjct: 421 ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 480

Query: 356 SATWPKEVRQLAEDFLR-DYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIM 414
           SAT+P+E+++LA +FL+ +Y  + VG +   A  ++ Q V    +  K  KL++++  I 
Sbjct: 481 SATFPEEIQRLAAEFLKSNYLFVAVGQVG-GACRDVQQTVLQVGQFSKREKLVEILRNIG 539

Query: 415 AEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIA 474
            E+   T++FVETK++ D +   + ++      IHGD+ Q ER+  L +FR GK P+L+A
Sbjct: 540 DER---TMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVA 596

Query: 475 TDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFF-TPGNLKQAREL 533
           T VA+RGLD+E+V+ VIN+D P++ ++YVHRIGRT R  N G A +FF    +   A+ L
Sbjct: 597 TSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPL 656

Query: 534 IKVLEEANQAI 544
           +KVL +A Q +
Sbjct: 657 VKVLTDAQQDV 667


>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
           [Homo sapiens]
          Length = 690

 Score =  283 bits (725), Expect = 3e-76
 Identities = 180/491 (36%), Positives = 277/491 (56%), Gaps = 28/491 (5%)

Query: 77  FGTMRG--GGFGDRDRDRDRGGFGARGGG--GLPPKKFGNPGERLRKKKWDLSELPKFE- 131
           FG+ R    G G+ D  + R G G+  GG  GL  +     G+   K + +  E    + 
Sbjct: 148 FGSRRPVLSGTGNGDTSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGESSDTQG 207

Query: 132 -KNFYVEHP----EVARLTPYEVDELRRKKE---ITVRGGDVCPKPVFAFHHANFPQYVM 183
            K  Y+  P    E +    Y+      K +   + V G D  P  +  F  AN  Q + 
Sbjct: 208 PKVTYIPPPPPEDEDSIFAHYQTGINFDKYDTILVEVSGHDA-PPAILTFEEANLCQTLN 266

Query: 184 DVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPY----L 239
           + +    +T+ TP+Q    P+ L+GRD++  AQTGSGKT A+LLP + H+ H        
Sbjct: 267 NNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRF 326

Query: 240 ERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICI 299
           +    P C+++APTREL  Q+   A  +   + +++  IYGG   G  IR + +G  I  
Sbjct: 327 KELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILC 386

Query: 300 ATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVD----QIRPDRQTLMW 355
           ATPGRL+D +   K  L++  YLVLDEADRMLDMGF P+++K++       +  RQTLM+
Sbjct: 387 ATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMF 446

Query: 356 SATWPKEVRQLAEDFLR-DYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIM 414
           SAT+P+E+++LA +FL+ +Y  + VG +   A  ++ Q V    +  K  KL++++  I 
Sbjct: 447 SATFPEEIQRLAAEFLKSNYLFVAVGQVG-GACRDVQQTVLQVGQFSKREKLVEILRNIG 505

Query: 415 AEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIA 474
            E+   T++FVETK++ D +   + ++      IHGD+ Q ER+  L +FR GK P+L+A
Sbjct: 506 DER---TMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVA 562

Query: 475 TDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFF-TPGNLKQAREL 533
           T VA+RGLD+E+V+ VIN+D P++ ++YVHRIGRT R  N G A +FF    +   A+ L
Sbjct: 563 TSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPL 622

Query: 534 IKVLEEANQAI 544
           +KVL +A Q +
Sbjct: 623 VKVLTDAQQDV 633


>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
          Length = 622

 Score =  267 bits (683), Expect = 2e-71
 Identities = 165/413 (39%), Positives = 230/413 (55%), Gaps = 18/413 (4%)

Query: 150 DELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGR 209
           + +R+K  I V G D  P P+ +F    FP  ++  L  +    PTPIQ QG P  LSGR
Sbjct: 161 ERVRKKYHILVEG-DGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGR 219

Query: 210 DMVGIAQTGSGKTLAYLLPAIVHINHQ----PYLERGDGPICLVLAPTRELAQQVQQVAD 265
           DM+GIA TGSGKTL + LP I+    Q    P+ +R +GP  L++ P+RELA+Q   + +
Sbjct: 220 DMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKR-EGPYGLIICPSRELARQTHGILE 278

Query: 266 DYGKCSR------LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRRC 319
            Y +  +      L+     GG     Q+  +  GV + +ATPGRL+D L+    +L  C
Sbjct: 279 YYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDIC 338

Query: 320 TYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINV 379
            YL LDEADRM+DMGFE  IR I    +  RQTL++SAT PK+++  A+  L     INV
Sbjct: 339 RYLALDEADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINV 398

Query: 380 GNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMR 439
           G    +A+ +++Q V+   E   + K++ L+ E + +     +IF E K   D +   + 
Sbjct: 399 GRAG-AASLDVIQEVEYVKE---EAKMVYLL-ECLQKTPPPVLIFAEKKADVDAIHEYLL 453

Query: 440 RDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSS 499
             G  A+ IHG K Q ER   +  FR GK  +L+ATDVAS+GLD   ++ VINYD P   
Sbjct: 454 LKGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEI 513

Query: 500 EDYVHRIGRTARSTNKGTAYTFFTPG-NLKQARELIKVLEEANQAINPKLMQL 551
           E+YVHRIGRT RS N G A TF     +     +L  +L EA Q + P L  L
Sbjct: 514 ENYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVLQVL 566


>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
           sapiens]
          Length = 619

 Score =  242 bits (617), Expect = 1e-63
 Identities = 146/426 (34%), Positives = 232/426 (54%), Gaps = 10/426 (2%)

Query: 126 ELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDV 185
           E P      Y EHP +  L   +++ L+++  I V+G +V  +P+  F H + P+ +   
Sbjct: 159 ESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVT-RPIIDFEHCSLPEVLNHN 217

Query: 186 LMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGP 245
           L    +  PTPIQ Q  P+ L GRD++  A TGSGKT A+LLP I+       L     P
Sbjct: 218 LKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRA-----LFESKTP 272

Query: 246 ICLVLAPTRELAQQVQQVADDY-GKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGR 304
             L+L PTRELA Q+++ A +      R+K+  + GG P  PQ+  L++ V++ IATPGR
Sbjct: 273 SALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGR 332

Query: 305 LIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVR 364
           L+D ++     L     +V+DEAD ML MGF+ Q+  I++ I  D QT++ SAT P  + 
Sbjct: 333 LLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTSIE 392

Query: 365 QLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIF 424
           QLA   L +  +I  G   L    N+ QI+    +  K  KL +++ +    K    ++F
Sbjct: 393 QLASQLLHNPVRIITGEKNLPC-ANVRQIILWVEDPAKKKKLFEILNDKKLFKP-PVLVF 450

Query: 425 VETKRRCDDLTRRMRR-DGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLD 483
           V+ K   D L+  +++  G  ++ IH +KSQ ER  +L     G   ++++T V  RGLD
Sbjct: 451 VDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRGLD 510

Query: 484 VEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQA 543
           +  V+ V+N+D P+S ++YVH+IGR  R    GTA TF    + +   ++ K ++     
Sbjct: 511 LISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVKPTGSI 570

Query: 544 INPKLM 549
           + P+L+
Sbjct: 571 LPPQLL 576


>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score =  222 bits (566), Expect = 8e-58
 Identities = 150/397 (37%), Positives = 211/397 (53%), Gaps = 34/397 (8%)

Query: 191 FTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVL 250
           +T+PT IQ +  PLAL GRD++G+A+TGSGKT A+ LP +        LE       LVL
Sbjct: 44  WTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL-----NALLETPQRLFALVL 98

Query: 251 APTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 310
            PTRELA Q+ +  +  G    ++S  I GG     Q   L +   I IATPGRLID LE
Sbjct: 99  TPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLE 158

Query: 311 SGKT-NLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAED 369
           + K  NLR   YLV+DEADR+L+M FE ++ KI+  I  DR+T ++SAT  K+V++L   
Sbjct: 159 NTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRA 218

Query: 370 FLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKR 429
            L++  +  V + +      + Q         KD  L+ ++ E+     N  +IF  T  
Sbjct: 219 ALKNPVKCAVSS-KYQTVEKLQQYYIFIPSKFKDTYLVYILNELAG---NSFMIFCSTCN 274

Query: 430 RCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKF 489
                   +R  G+ A+ +HG  SQ +R   LN+F++    IL+ATDVASRGLD+  V  
Sbjct: 275 NTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDV 334

Query: 490 VINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFT------------------PGNLKQAR 531
           V+N+D P  S+DY+HR+GRTAR+   G A TF T                  PG   Q  
Sbjct: 335 VVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDD 394

Query: 532 ELIKVLEEANQAINPKLMQLVDHRGGGGGGGKGGRSR 568
           E++ + E   +A     M+L +H      G K  RSR
Sbjct: 395 EVMMLTERVAEAQRFARMELREH------GEKKKRSR 425


>gi|13129006 nucleolar protein GU2 [Homo sapiens]
          Length = 737

 Score =  206 bits (524), Expect = 6e-53
 Identities = 124/366 (33%), Positives = 202/366 (55%), Gaps = 14/366 (3%)

Query: 176 ANFP--QYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHI 233
           +NFP  +  + +L  +  T   PIQ + F     G+D++  A+TG+GKT ++ +P I  +
Sbjct: 140 SNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERL 199

Query: 234 N-HQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLE 292
             +Q  +++   P  LVLAPTRELA QV +   D  +  +L   C YGG     QI  + 
Sbjct: 200 QRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITR--KLSVACFYGGTSYQSQINHIR 257

Query: 293 RGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQI-----R 347
            G++I + TPGR+ D L+SG+ +L +  ++VLDE D+MLD+GF  Q+  I+ +       
Sbjct: 258 NGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKTDSE 317

Query: 348 PDRQTLMWSATWPKEVRQLAEDFLRD-YTQIN-VGNLELSANHNILQIVDVCMESEKDHK 405
            + QTL++SAT P+ V ++A+ +++  Y Q++ VG +   A   +  +   C  S++   
Sbjct: 318 DNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCHWSQRPAV 377

Query: 406 LIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFR 465
           +  +++ + +  E + IIF ETK+   ++          A C+HGD +Q +R+  L  FR
Sbjct: 378 IGDVLQ-VYSGSEGRAIIFCETKKNVTEMAMNPHIKQ-NAQCLHGDIAQSQREITLKGFR 435

Query: 466 SGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPG 525
            G   +L+AT+VA+RGLD+ +V  VI    P   E Y+HR GRT R+   G    F+ P 
Sbjct: 436 EGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICFYQPR 495

Query: 526 NLKQAR 531
              Q R
Sbjct: 496 ERGQLR 501


>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
           sapiens]
          Length = 483

 Score =  205 bits (521), Expect = 1e-52
 Identities = 132/352 (37%), Positives = 190/352 (53%), Gaps = 15/352 (4%)

Query: 193 EPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAP 252
           +PTP+Q    P  L GRD +G A+TGSGKT A++LP +  ++  PY     G  CLVL P
Sbjct: 24  QPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPY-----GIFCLVLTP 78

Query: 253 TRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESG 312
           TRELA Q+ +     GK   LK   I GG     Q  +L R   + IATPGRL D L S 
Sbjct: 79  TRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHVVIATPGRLADHLRSS 138

Query: 313 KT-NLRRCTYLVLDEADRMLDMG---FEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAE 368
            T ++++  +LV+DEADR+L+ G   F   +  I+  +   RQTL++SAT    +R+L +
Sbjct: 139 NTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARRQTLLFSATLTDTLREL-Q 197

Query: 369 DFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKEN-KTIIFVET 427
               +          +S    + Q   +  E  KD  L+ L++    E E+   IIF  T
Sbjct: 198 GLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQDEHEDWSIIIFTNT 257

Query: 428 KRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDV 487
            + C  L   +R+  +P + +H    Q ER   L +F+S    ILIATDVASRGLD+  V
Sbjct: 258 CKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILIATDVASRGLDIPTV 317

Query: 488 KFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEE 539
           + VIN++ P   + Y+HR+GRTAR+  +G A T  T  ++     L+  +EE
Sbjct: 318 QVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDI----HLVHAIEE 365


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
           sapiens]
          Length = 783

 Score =  204 bits (518), Expect = 3e-52
 Identities = 126/376 (33%), Positives = 211/376 (56%), Gaps = 19/376 (5%)

Query: 176 ANFP--QYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHI 233
           +NFP  +  + +L  +  T   PIQ + F    SG+D++  A+TG+GKT ++ +P I  +
Sbjct: 189 SNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIEKL 248

Query: 234 NHQPY-LERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLE 292
           + +    +RG  P  LVLAPTRELA QV +   D  K  +L   C YGG P G Q   + 
Sbjct: 249 HGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITK--KLSVACFYGGTPYGGQFERMR 306

Query: 293 RGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVD-----QIR 347
            G++I + TPGR+ D +++GK +L +  ++VLDE D+MLDMGF  Q+ +I+         
Sbjct: 307 NGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKKDSE 366

Query: 348 PDRQTLMWSATWPKEVRQLAEDFLRD-YTQINVGNLELSANHNILQIVDVCMESEKDHKL 406
            + QTL++SAT P  V  +A+ +++  Y Q+++   +       ++ + +     +   +
Sbjct: 367 DNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKCHWTQRAAV 426

Query: 407 IQLMEEIMAEKENKTIIFVETKRRCDDLTRR--MRRDGWPAMCIHGDKSQPERDWVLNEF 464
           I  +  + +  + +TIIF ETK+   +L++   +++D   A  +HGD  Q +R+  L  F
Sbjct: 427 IGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQD---AQSLHGDIPQKQREITLKGF 483

Query: 465 RSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTP 524
           R+G   +L+AT+VA+RGLD+ +V  VI    P   E Y+HR GRT R+   G    F+  
Sbjct: 484 RNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFY-- 541

Query: 525 GNLKQARELIKVLEEA 540
              K+  +L++V ++A
Sbjct: 542 -QHKEEYQLVQVEQKA 556


>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
           [Homo sapiens]
          Length = 411

 Score =  201 bits (510), Expect = 3e-51
 Identities = 121/343 (35%), Positives = 181/343 (52%), Gaps = 8/343 (2%)

Query: 191 FTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVL 250
           F +P+ IQ +     + GRD++  +Q+G+GKT  + +  +  ++ Q    +      L+L
Sbjct: 58  FEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQA-----LIL 112

Query: 251 APTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 310
           APTRELA Q+Q+     G    ++     GG   G  IR L+ G  +   TPGR+ D + 
Sbjct: 113 APTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIR 172

Query: 311 SGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDF 370
                 R    LVLDEAD ML+ GF+ QI  +   + P  Q ++ SAT P E+ ++   F
Sbjct: 173 RRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKF 232

Query: 371 LRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRR 430
           + D  +I V   EL+        V V  E  K   L  L + +      + +IF  TKR+
Sbjct: 233 MTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTI---TQAVIFCNTKRK 289

Query: 431 CDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFV 490
            D LT +MR   +    +HGD  Q ER+ ++ EFRSG + +LI+TDV +RGLDV  V  +
Sbjct: 290 VDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLI 349

Query: 491 INYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQAREL 533
           INYD PN+ E Y+HRIGR+ R   KG A  F    +++  R++
Sbjct: 350 INYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDI 392


>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score =  195 bits (496), Expect = 1e-49
 Identities = 121/365 (33%), Positives = 187/365 (51%), Gaps = 9/365 (2%)

Query: 170 VFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPA 229
           V +F   N  + ++  +    F +P+ IQ +     + G D++  AQ+G+GKT  + +  
Sbjct: 31  VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISI 90

Query: 230 IVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIR 289
           +  I       +      LVLAPTRELAQQ+Q+V    G           GG     +++
Sbjct: 91  LQQIELDLKATQA-----LVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQ 145

Query: 290 DLE-RGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRP 348
            L+     I + TPGR+ D L     + +     VLDEAD ML  GF+ QI  I  ++  
Sbjct: 146 KLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNS 205

Query: 349 DRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQ 408
           + Q ++ SAT P +V ++ + F+RD  +I V   EL+        ++V  E  K   L  
Sbjct: 206 NTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCD 265

Query: 409 LMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGK 468
           L E +      + +IF+ T+R+ D LT +M    +    +HGD  Q ERD ++ EFRSG 
Sbjct: 266 LYETLTI---TQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGS 322

Query: 469 APILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLK 528
           + +LI TD+ +RG+DV+ V  VINYD P + E+Y+HRIGR  R   KG A    T  + +
Sbjct: 323 SRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKR 382

Query: 529 QAREL 533
             R++
Sbjct: 383 TLRDI 387


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score =  191 bits (486), Expect = 2e-48
 Identities = 121/362 (33%), Positives = 188/362 (51%), Gaps = 9/362 (2%)

Query: 173 FHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVH 232
           F   N  + ++  +    F +P+ IQ +     + G D++  AQ+G+GKT  + +  +  
Sbjct: 35  FDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQ 94

Query: 233 INHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLE 292
           +  + + E       LVLAPTRELAQQ+Q+V    G           GG     +++ L+
Sbjct: 95  LEIE-FKETQ----ALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQ 149

Query: 293 -RGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQ 351
                I + TPGR+ D L     + +     VLDEAD ML  GF+ QI +I  ++    Q
Sbjct: 150 AEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQ 209

Query: 352 TLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLME 411
            ++ SAT P +V ++ + F+RD  +I V   EL+        ++V  E  K   L  L E
Sbjct: 210 VVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYE 269

Query: 412 EIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPI 471
            +      + +IF+ T+R+ D LT +M    +    +HGD  Q ERD ++ EFRSG + +
Sbjct: 270 TLTI---TQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRV 326

Query: 472 LIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQAR 531
           LI TD+ +RG+DV+ V  VINYD P + E+Y+HRIGR  R   KG A  F T  + +  R
Sbjct: 327 LITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILR 386

Query: 532 EL 533
           ++
Sbjct: 387 DI 388


>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
           [Homo sapiens]
          Length = 406

 Score =  190 bits (482), Expect = 5e-48
 Identities = 141/397 (35%), Positives = 195/397 (49%), Gaps = 83/397 (20%)

Query: 191 FTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVL 250
           +T+PT IQ +  PLAL GRD++G+A+TGSGKT A+ LP +        LE       LVL
Sbjct: 44  WTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL-----NALLETPQRLFALVL 98

Query: 251 APTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 310
            PTRELA Q+ +  +  G    ++S  I GG     Q   L +   I IATPGRLID LE
Sbjct: 99  TPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLE 158

Query: 311 SGKT-NLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAED 369
           + K  NLR   YLV+DEADR+L+M FE ++ KI+  I  DR+T ++SAT  K+V++L   
Sbjct: 159 NTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRA 218

Query: 370 FLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKR 429
            L++  +                    C  S K   +         EK  +  IF+ +  
Sbjct: 219 ALKNPVK--------------------CAVSSKYQTV---------EKLQQYYIFIPS-- 247

Query: 430 RCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKF 489
                                 K + +R   LN+F++    IL+ATDVASRGLD+  V  
Sbjct: 248 ----------------------KFKSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDV 285

Query: 490 VINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFT------------------PGNLKQAR 531
           V+N+D P  S+DY+HR+GRTAR+   G A TF T                  PG   Q  
Sbjct: 286 VVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDD 345

Query: 532 ELIKVLEEANQAINPKLMQLVDHRGGGGGGGKGGRSR 568
           E++ + E   +A     M+L +H      G K  RSR
Sbjct: 346 EVMMLTERVAEAQRFARMELREH------GEKKKRSR 376


>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
           [Homo sapiens]
          Length = 881

 Score =  190 bits (482), Expect = 5e-48
 Identities = 123/381 (32%), Positives = 192/381 (50%), Gaps = 9/381 (2%)

Query: 186 LMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGP 245
           +M + +  PTPIQ +  P+ L G+D+V +A+TGSGKT  +LLP    +          G 
Sbjct: 111 IMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKTH---SAQTGA 167

Query: 246 ICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRL 305
             L+L+PTRELA Q  +   + GK + LK+  I GG     Q   L    +I IATPGRL
Sbjct: 168 RALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHENPDIIIATPGRL 227

Query: 306 IDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQ 365
           +         L+   Y+V DEADR+ +MGF  Q+++I+ ++    QT+++SAT PK + +
Sbjct: 228 VHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVLFSATLPKLLVE 287

Query: 366 LAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFV 425
            A   L +   I + +++   N  +     +  E  K   L+ L+  ++   +++T++FV
Sbjct: 288 FARAGLTEPVLIRL-DVDTKLNEQLKTSFFLVREDTKAAVLLHLLHNVV-RPQDQTVVFV 345

Query: 426 ETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVE 485
            TK   + LT  +         I+       R   L +F  GK   LI TD+A+RGLD+ 
Sbjct: 346 ATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTDLAARGLDIP 405

Query: 486 DVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAIN 545
            +  VINY +P   + ++HR+GR AR+   GTAY+   P  +    +L   L  +     
Sbjct: 406 LLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYLLDLHLFLGRSLTLAR 465

Query: 546 PKLMQLVDHRGGGGGGGKGGR 566
           P    L +  G  G  G  GR
Sbjct: 466 P----LKEPSGVAGVDGMLGR 482


>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
           [Homo sapiens]
          Length = 882

 Score =  190 bits (482), Expect = 5e-48
 Identities = 123/381 (32%), Positives = 192/381 (50%), Gaps = 9/381 (2%)

Query: 186 LMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGP 245
           +M + +  PTPIQ +  P+ L G+D+V +A+TGSGKT  +LLP    +          G 
Sbjct: 111 IMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKTH---SAQTGA 167

Query: 246 ICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRL 305
             L+L+PTRELA Q  +   + GK + LK+  I GG     Q   L    +I IATPGRL
Sbjct: 168 RALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHENPDIIIATPGRL 227

Query: 306 IDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQ 365
           +         L+   Y+V DEADR+ +MGF  Q+++I+ ++    QT+++SAT PK + +
Sbjct: 228 VHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVLFSATLPKLLVE 287

Query: 366 LAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFV 425
            A   L +   I + +++   N  +     +  E  K   L+ L+  ++   +++T++FV
Sbjct: 288 FARAGLTEPVLIRL-DVDTKLNEQLKTSFFLVREDTKAAVLLHLLHNVV-RPQDQTVVFV 345

Query: 426 ETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVE 485
            TK   + LT  +         I+       R   L +F  GK   LI TD+A+RGLD+ 
Sbjct: 346 ATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTDLAARGLDIP 405

Query: 486 DVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAIN 545
            +  VINY +P   + ++HR+GR AR+   GTAY+   P  +    +L   L  +     
Sbjct: 406 LLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYLLDLHLFLGRSLTLAR 465

Query: 546 PKLMQLVDHRGGGGGGGKGGR 566
           P    L +  G  G  G  GR
Sbjct: 466 P----LKEPSGVAGVDGMLGR 482


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score =  189 bits (480), Expect = 8e-48
 Identities = 124/367 (33%), Positives = 192/367 (52%), Gaps = 8/367 (2%)

Query: 172 AFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIV 231
           +F   N  + ++  +    F +PTPIQ    P+ L G+D+   A TG+GKT A+ LP + 
Sbjct: 219 SFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLE 278

Query: 232 HINHQPYLERGDGPIC--LVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIR 289
            + ++P       P+   LVL PTREL  QV  V     +   + +    GG     Q  
Sbjct: 279 RLIYKPR----QAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEA 334

Query: 290 DLERGVEICIATPGRLIDFLESGKT-NLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRP 348
            L    +I IATPGRLID L +  + +L     L+LDEADRMLD  FE Q+++I+     
Sbjct: 335 ALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSH 394

Query: 349 DRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQ 408
            RQT+++SAT   EV+ LA   L++  +I V +    A     + + +    E D + I 
Sbjct: 395 HRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAI- 453

Query: 409 LMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGK 468
           +   +     +  ++F +TK++   +   +   G     +HG+ SQ +R   L  F+  +
Sbjct: 454 VAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQ 513

Query: 469 APILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLK 528
             IL+ATDVA+RGLD+E VK VIN+  PN+ + YVHR+GRTAR+   G + +       K
Sbjct: 514 IDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDERK 573

Query: 529 QARELIK 535
             +E++K
Sbjct: 574 MLKEIVK 580


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,557,827
Number of Sequences: 37866
Number of extensions: 1918705
Number of successful extensions: 26002
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 237
Number of HSP's successfully gapped in prelim test: 432
Number of HSP's that attempted gapping in prelim test: 19014
Number of HSP's gapped (non-prelim): 5713
length of query: 731
length of database: 18,247,518
effective HSP length: 110
effective length of query: 621
effective length of database: 14,082,258
effective search space: 8745082218
effective search space used: 8745082218
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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