BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|148612887 choline transporter-like protein 4 [Homo sapiens] (710 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|148612887 choline transporter-like protein 4 [Homo sapiens] 1447 0.0 gi|222831610 solute carrier family 44, member 2 isoform 2 [Homo ... 730 0.0 gi|222831612 solute carrier family 44, member 2 isoform 1 [Homo ... 728 0.0 gi|194239633 solute carrier family 44, member 5 isoform B [Homo ... 697 0.0 gi|194239631 solute carrier family 44, member 5 isoform A [Homo ... 692 0.0 gi|18034692 CDW92 antigen [Homo sapiens] 250 3e-66 gi|166235173 solute carrier family 44, member 3 isoform 1 [Homo ... 218 1e-56 gi|166235171 solute carrier family 44, member 3 isoform 2 [Homo ... 206 5e-53 gi|21264580 tetraspan 2 [Homo sapiens] 36 0.11 gi|4502827 cholinergic receptor, nicotinic, alpha 4 subunit prec... 33 1.2 gi|157388902 semaphorin 4C [Homo sapiens] 32 1.6 gi|4502187 aquaporin 7 [Homo sapiens] 30 5.9 gi|21729876 ATP-binding cassette, sub-family C, member 11 isofor... 30 7.7 gi|21729873 ATP-binding cassette, sub-family C, member 11 isofor... 30 7.7 gi|15149474 ATP-binding cassette, sub-family C, member 11 isofor... 30 7.7 >gi|148612887 choline transporter-like protein 4 [Homo sapiens] Length = 710 Score = 1447 bits (3745), Expect = 0.0 Identities = 710/710 (100%), Positives = 710/710 (100%) Query: 1 MGGKQRDEDDEAYGKPVKYDPSFRGPIKNRSCTDVICCVLFLLFILGYIVVGIVAWLYGD 60 MGGKQRDEDDEAYGKPVKYDPSFRGPIKNRSCTDVICCVLFLLFILGYIVVGIVAWLYGD Sbjct: 1 MGGKQRDEDDEAYGKPVKYDPSFRGPIKNRSCTDVICCVLFLLFILGYIVVGIVAWLYGD 60 Query: 61 PRQVLYPRNSTGAYCGMGENKDKPYLLYFNIFSCILSSNIISVAENGLQCPTPQVCVSSC 120 PRQVLYPRNSTGAYCGMGENKDKPYLLYFNIFSCILSSNIISVAENGLQCPTPQVCVSSC Sbjct: 61 PRQVLYPRNSTGAYCGMGENKDKPYLLYFNIFSCILSSNIISVAENGLQCPTPQVCVSSC 120 Query: 121 PEDPWTVGKNEFSQTVGEVFYTKNRNFCLPGVPWNMTVITSLQQELCPSFLLPSAPALGR 180 PEDPWTVGKNEFSQTVGEVFYTKNRNFCLPGVPWNMTVITSLQQELCPSFLLPSAPALGR Sbjct: 121 PEDPWTVGKNEFSQTVGEVFYTKNRNFCLPGVPWNMTVITSLQQELCPSFLLPSAPALGR 180 Query: 181 CFPWTNVTPPALPGITNDTTIQQGISGLIDSLNARDISVKIFEDFAQSWYWILVALGVAL 240 CFPWTNVTPPALPGITNDTTIQQGISGLIDSLNARDISVKIFEDFAQSWYWILVALGVAL Sbjct: 181 CFPWTNVTPPALPGITNDTTIQQGISGLIDSLNARDISVKIFEDFAQSWYWILVALGVAL 240 Query: 241 VLSLLFILLLRLVAGPLVLVLILGVLGVLAYGIYYCWEEYRVLRDKGASISQLGFTTNLS 300 VLSLLFILLLRLVAGPLVLVLILGVLGVLAYGIYYCWEEYRVLRDKGASISQLGFTTNLS Sbjct: 241 VLSLLFILLLRLVAGPLVLVLILGVLGVLAYGIYYCWEEYRVLRDKGASISQLGFTTNLS 300 Query: 301 AYQSVQETWLAALIVLAVLEAILLLMLIFLRQRIRIAIALLKEASKAVGQMMSTMFYPLV 360 AYQSVQETWLAALIVLAVLEAILLLMLIFLRQRIRIAIALLKEASKAVGQMMSTMFYPLV Sbjct: 301 AYQSVQETWLAALIVLAVLEAILLLMLIFLRQRIRIAIALLKEASKAVGQMMSTMFYPLV 360 Query: 361 TFVLLLICIAYWAMTALYLATSGQPQYVLWASNISSPGCEKVPINTSCNPTAHLVNSSCP 420 TFVLLLICIAYWAMTALYLATSGQPQYVLWASNISSPGCEKVPINTSCNPTAHLVNSSCP Sbjct: 361 TFVLLLICIAYWAMTALYLATSGQPQYVLWASNISSPGCEKVPINTSCNPTAHLVNSSCP 420 Query: 421 GLMCVFQGYSSKGLIQRSVFNLQIYGVLGLFWTLNWVLALGQCVLAGAFASFYWAFHKPQ 480 GLMCVFQGYSSKGLIQRSVFNLQIYGVLGLFWTLNWVLALGQCVLAGAFASFYWAFHKPQ Sbjct: 421 GLMCVFQGYSSKGLIQRSVFNLQIYGVLGLFWTLNWVLALGQCVLAGAFASFYWAFHKPQ 480 Query: 481 DIPTFPLISAFIRTLRYHTGSLAFGALILTLVQIARVILEYIDHKLRGVQNPVARCIMCC 540 DIPTFPLISAFIRTLRYHTGSLAFGALILTLVQIARVILEYIDHKLRGVQNPVARCIMCC Sbjct: 481 DIPTFPLISAFIRTLRYHTGSLAFGALILTLVQIARVILEYIDHKLRGVQNPVARCIMCC 540 Query: 541 FKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNIVRVVVLDKVTDLLLF 600 FKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNIVRVVVLDKVTDLLLF Sbjct: 541 FKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNIVRVVVLDKVTDLLLF 600 Query: 601 FGKLLVVGGVGVLSFFFFSGRIPGLGKDFKSPHLNYYWLPIMTSILGAYVIASGFFSVFG 660 FGKLLVVGGVGVLSFFFFSGRIPGLGKDFKSPHLNYYWLPIMTSILGAYVIASGFFSVFG Sbjct: 601 FGKLLVVGGVGVLSFFFFSGRIPGLGKDFKSPHLNYYWLPIMTSILGAYVIASGFFSVFG 660 Query: 661 MCVDTLFLCFLEDLERNNGSLDRPYYMSKSLLKILGKKNEAPPDNKKRKK 710 MCVDTLFLCFLEDLERNNGSLDRPYYMSKSLLKILGKKNEAPPDNKKRKK Sbjct: 661 MCVDTLFLCFLEDLERNNGSLDRPYYMSKSLLKILGKKNEAPPDNKKRKK 710 >gi|222831610 solute carrier family 44, member 2 isoform 2 [Homo sapiens] Length = 704 Score = 730 bits (1885), Expect = 0.0 Identities = 377/710 (53%), Positives = 489/710 (68%), Gaps = 40/710 (5%) Query: 12 AYGKPVKYDPSFRGPIKNRSCTDVICCVLFLLFILGYIVVGIVAWLYGDPRQVLYPRNST 71 AYG P KYDP+F+GPI NR CTD+ICCV LL I+GY+ VGI+AW +GDPR+V+YP +S Sbjct: 9 AYGTPQKYDPTFKGPIYNRGCTDIICCVFLLLAIVGYVAVGIIAWTHGDPRKVIYPTDSR 68 Query: 72 GAYCGMG--ENKDKPYLLYFNIFSCILSSNIISVAENGLQCPTPQVCVSSCPEDPWTVGK 129 G +CG +N++KPYL YFNI C ++ QCPTPQ+CV CP D + Sbjct: 69 GEFCGQKGTKNENKPYLFYFNIVKCASPLVLLE-----FQCPTPQICVEKCP-DRYLTYL 122 Query: 130 NEFSQTVGEVFYTKNRNFCLPGVPWNMTVITSLQQELCPSFLLPSAPALGRCFPWTNVTP 189 N S E + + FC+PG N V LQ CP+ L+PS P RCFP + Sbjct: 123 NARSSRDFEYY----KQFCVPGFKNNKGVAEVLQDGDCPAVLIPSKPLARRCFPAIHAYK 178 Query: 190 PALPGITNDTTIQQG------ISGLIDS-------LNARDISVKIFEDFAQSWYWILVAL 236 L + N+TT + G I+ L++ L AR ++++IFED+ SWYWI++ L Sbjct: 179 GVLM-VGNETTYEDGHGSRKNITDLVEGAKKANGVLEARQLAMRIFEDYTVSWYWIIIGL 237 Query: 237 GVALVLSLLFILLLRLVAGPLVLVLILGVLGVLAYGIYYCWEEYRVLRDKGAS---ISQL 293 +A+ +SLLFI+LLR +AG +V V+I+ V+ VL YGI++C+ EY LR + S + L Sbjct: 238 VIAMAMSLLFIILLRFLAGIMVWVMIIMVILVLGYGIFHCYMEYSRLRGEAGSDVSLVDL 297 Query: 294 GFTTNLSAYQSVQETWLAALIVLAVLEAILLLMLIFLRQRIRIAIALLKEASKAVGQMMS 353 GF T+ Y +++TWLA +I+L++LE I++L+LIFLR+RI IAIAL+KEAS+AVG +M Sbjct: 298 GFQTDFRVYLHLRQTWLAFMIILSILEVIIILLLIFLRKRILIAIALIKEASRAVGYVMC 357 Query: 354 TMFYPLVTFVLLLICIAYWAMTALYLATSGQPQYVLWASNISSPGCEKVPINTSCNP-TA 412 ++ YPLVTF LL +CIAYWA TA++L+TS + Y ++ + P K +CNP T Sbjct: 358 SLLYPLVTFFLLCLCIAYWASTAVFLSTSNEAVYKIFDDS-PCPFTAK-----TCNPETF 411 Query: 413 HLVNSS--CPGLMCVFQGYSSKGLIQRSVFNLQIYGVLGLFWTLNWVLALGQCVLAGAFA 470 N S CP C F Y + R++ LQI+ FW N+VLALGQ LAGAFA Sbjct: 412 PSSNESRQCPNARCQFAFYGGESGYHRALLGLQIFNAFMFFWLANFVLALGQVTLAGAFA 471 Query: 471 SFYWAFHKPQDIPTFPLISAFIRTLRYHTGSLAFGALILTLVQIARVILEYIDHKLRGVQ 530 S+YWA KP D+P FPL SAF R LRYHTGSLAFGALIL +VQI RVILEY+D +L+ + Sbjct: 472 SYYWALRKPDDLPAFPLFSAFGRALRYHTGSLAFGALILAIVQIIRVILEYLDQRLKAAE 531 Query: 531 NPVARCIMCCFKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNIVRVVV 590 N A+C+M C KCC WCLEKFIKFLNRNAYIMIAIYG NFC SA+NAF LLMRNI+RV V Sbjct: 532 NKFAKCLMTCLKCCFWCLEKFIKFLNRNAYIMIAIYGTNFCTSARNAFFLLMRNIIRVAV 591 Query: 591 LDKVTDLLLFFGKLLVVGGVGVLSFFFFSGRIPGLGKDFKSPHLNYYWLPIMTSILGAYV 650 LDKVTD L GKLL+VG VG+L+FFFF+ RI + +D +P LNYYW+PI+T I+G+Y+ Sbjct: 592 LDKVTDFLFLLGKLLIVGSVGILAFFFFTHRI-RIVQD-TAPPLNYYWVPILTVIVGSYL 649 Query: 651 IASGFFSVFGMCVDTLFLCFLEDLERNNGSLDRPYYMSKSLLKILGKKNE 700 IA GFFSV+GMCVDTLFLCFLEDLERN+GS +RPY+MS +L K+L K N+ Sbjct: 650 IAHGFFSVYGMCVDTLFLCFLEDLERNDGSAERPYFMSSTLKKLLNKTNK 699 >gi|222831612 solute carrier family 44, member 2 isoform 1 [Homo sapiens] Length = 706 Score = 728 bits (1879), Expect = 0.0 Identities = 379/718 (52%), Positives = 491/718 (68%), Gaps = 43/718 (5%) Query: 7 DEDDEAYGK---PVKYDPSFRGPIKNRSCTDVICCVLFLLFILGYIVVGIVAWLYGDPRQ 63 DE YGK P KYDP+F+GPI NR CTD+ICCV LL I+GY+ VGI+AW +GDPR+ Sbjct: 3 DERPHYYGKHGTPQKYDPTFKGPIYNRGCTDIICCVFLLLAIVGYVAVGIIAWTHGDPRK 62 Query: 64 VLYPRNSTGAYCGMG--ENKDKPYLLYFNIFSCILSSNIISVAENGLQCPTPQVCVSSCP 121 V+YP +S G +CG +N++KPYL YFNI C ++ QCPTPQ+CV CP Sbjct: 63 VIYPTDSRGEFCGQKGTKNENKPYLFYFNIVKCASPLVLLE-----FQCPTPQICVEKCP 117 Query: 122 EDPWTVGKNEFSQTVGEVFYTKNRNFCLPGVPWNMTVITSLQQELCPSFLLPSAPALGRC 181 D + N S E + + FC+PG N V LQ CP+ L+PS P RC Sbjct: 118 -DRYLTYLNARSSRDFEYY----KQFCVPGFKNNKGVAEVLQDGDCPAVLIPSKPLARRC 172 Query: 182 FPWTNVTPPALPGITNDTTIQQG------ISGLIDS-------LNARDISVKIFEDFAQS 228 FP + L + N+TT + G I+ L++ L AR ++++IFED+ S Sbjct: 173 FPAIHAYKGVLM-VGNETTYEDGHGSRKNITDLVEGAKKANGVLEARQLAMRIFEDYTVS 231 Query: 229 WYWILVALGVALVLSLLFILLLRLVAGPLVLVLILGVLGVLAYGIYYCWEEYRVLRDKGA 288 WYWI++ L +A+ +SLLFI+LLR +AG +V V+I+ V+ VL YGI++C+ EY LR + Sbjct: 232 WYWIIIGLVIAMAMSLLFIILLRFLAGIMVWVMIIMVILVLGYGIFHCYMEYSRLRGEAG 291 Query: 289 S---ISQLGFTTNLSAYQSVQETWLAALIVLAVLEAILLLMLIFLRQRIRIAIALLKEAS 345 S + LGF T+ Y +++TWLA +I+L++LE I++L+LIFLR+RI IAIAL+KEAS Sbjct: 292 SDVSLVDLGFQTDFRVYLHLRQTWLAFMIILSILEVIIILLLIFLRKRILIAIALIKEAS 351 Query: 346 KAVGQMMSTMFYPLVTFVLLLICIAYWAMTALYLATSGQPQYVLWASNISSPGCEKVPIN 405 +AVG +M ++ YPLVTF LL +CIAYWA TA++L+TS + Y ++ + P K Sbjct: 352 RAVGYVMCSLLYPLVTFFLLCLCIAYWASTAVFLSTSNEAVYKIFDDS-PCPFTAK---- 406 Query: 406 TSCNP-TAHLVNSS--CPGLMCVFQGYSSKGLIQRSVFNLQIYGVLGLFWTLNWVLALGQ 462 +CNP T N S CP C F Y + R++ LQI+ FW N+VLALGQ Sbjct: 407 -TCNPETFPSSNESRQCPNARCQFAFYGGESGYHRALLGLQIFNAFMFFWLANFVLALGQ 465 Query: 463 CVLAGAFASFYWAFHKPQDIPTFPLISAFIRTLRYHTGSLAFGALILTLVQIARVILEYI 522 LAGAFAS+YWA KP D+P FPL SAF R LRYHTGSLAFGALIL +VQI RVILEY+ Sbjct: 466 VTLAGAFASYYWALRKPDDLPAFPLFSAFGRALRYHTGSLAFGALILAIVQIIRVILEYL 525 Query: 523 DHKLRGVQNPVARCIMCCFKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLM 582 D +L+ +N A+C+M C KCC WCLEKFIKFLNRNAYIMIAIYG NFC SA+NAF LLM Sbjct: 526 DQRLKAAENKFAKCLMTCLKCCFWCLEKFIKFLNRNAYIMIAIYGTNFCTSARNAFFLLM 585 Query: 583 RNIVRVVVLDKVTDLLLFFGKLLVVGGVGVLSFFFFSGRIPGLGKDFKSPHLNYYWLPIM 642 RNI+RV VLDKVTD L GKLL+VG VG+L+FFFF+ RI + +D +P LNYYW+PI+ Sbjct: 586 RNIIRVAVLDKVTDFLFLLGKLLIVGSVGILAFFFFTHRI-RIVQD-TAPPLNYYWVPIL 643 Query: 643 TSILGAYVIASGFFSVFGMCVDTLFLCFLEDLERNNGSLDRPYYMSKSLLKILGKKNE 700 T I+G+Y+IA GFFSV+GMCVDTLFLCFLEDLERN+GS +RPY+MS +L K+L K N+ Sbjct: 644 TVIVGSYLIAHGFFSVYGMCVDTLFLCFLEDLERNDGSAERPYFMSSTLKKLLNKTNK 701 >gi|194239633 solute carrier family 44, member 5 isoform B [Homo sapiens] Length = 717 Score = 697 bits (1800), Expect = 0.0 Identities = 338/721 (46%), Positives = 487/721 (67%), Gaps = 37/721 (5%) Query: 9 DDEAYGKPVKYDPSFRGPIKNRSCTDVICCVLFLLFILGYIVVGIVAWLYGDPRQVLYPR 68 ++E +G P YDP F+GP+ NRSCTDV+CC++FLL I+GYIV+G+VAW++GDPR+ YP Sbjct: 13 EEEDFGDPRTYDPDFKGPVANRSCTDVLCCMIFLLCIIGYIVLGLVAWVHGDPRRAAYPT 72 Query: 69 NSTGAYCGMG--ENKDKPYLLYFNIFSCILSSNIISVAENGLQCPTPQVCVSSCPEDPWT 126 +S G +CG N++K L YFN+ C S +++ LQCPT Q+CVS CPE T Sbjct: 73 DSQGHFCGQKGTPNENKTILFYFNLLRCTSPSVLLN-----LQCPTTQICVSKCPEKFLT 127 Query: 127 VGKNEFSQTVGEVFYTKNRNFCLPGVPWNMTVITSLQQELCPSFLLPSAPALGRCFPWTN 186 + + T + ++ R FC ++ L + CP+ + PS P L RCFP + Sbjct: 128 YVEMQLLYTKDKSYWEDYRQFCKTTAKPVKSLTQLLLDDDCPTAIFPSKPFLQRCFPDFS 187 Query: 187 VTPPALPGITNDTTIQQG-------------ISGLIDSLNARDISVKIFEDFAQSWYWIL 233 L I + Q G +G+ L+A+ + +K+FED+A++WYWIL Sbjct: 188 TKNGTLT-IGSKMMFQDGNGGTRSVVELGIAANGINKLLDAKSLGLKVFEDYARTWYWIL 246 Query: 234 VALGVALVLSLLFILLLRLVAGPLVLVLILGVLGVLAYGIYYCWEEYRVLRDKGAS---I 290 + L +A+VLS +F++LLR +AG L V ++GV+G++ YGI++C+++Y L+++ +S I Sbjct: 247 IGLTIAMVLSWIFLILLRFIAGCLFWVFMIGVIGIIGYGIWHCYQQYTNLQERPSSVLTI 306 Query: 291 SQLGFTTNLSAYQSVQETWLAALIVLAVLEAILLLMLIFLRQRIRIAIALLKEASKAVGQ 350 +G TN+S Y +Q+TW +I+L ++E I++LMLIFLR RIR+AI LLKE SKA+G Sbjct: 307 YDIGIQTNISMYFELQQTWFTFMIILCIIEVIVILMLIFLRNRIRVAIILLKEGSKAIGY 366 Query: 351 MMSTMFYPLVTFVLLLICIAYWAMTALYLATSGQPQYVLWASNISSPGCEKVPINTSCNP 410 + ST+ YP +TF+LL ICI YW +TA++LATSG P Y + +PG + N +C+P Sbjct: 367 VPSTLVYPALTFILLSICICYWVVTAVFLATSGVPVY-----KVIAPGGHCIHENQTCDP 421 Query: 411 ---TAHLVNSSCPGLMCVFQGYSSKGLIQRSVFNLQIYGVLGLFWTLNWVLALGQCVLAG 467 + +CPG +C F Y K L + + +Y + W +N+V+ALGQC LAG Sbjct: 422 EIFNTTEIAKACPGALCNFAFYGGKSLYHQYIPTFHVYNLFVFLWLINFVIALGQCALAG 481 Query: 468 AFASFYWAFHKPQDIPTFPLISAFIRTLRYHTGSLAFGALILTLVQIARVILEYIDHKLR 527 AFA++YWA KP DIP +PL +AF R +RYHTGSLAFG+LI+ L+Q+ +++LEY+DH+L+ Sbjct: 482 AFATYYWAMKKPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLDHRLK 541 Query: 528 GVQNPVARCIMCCFKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNIVR 587 QN +++ + CC +CC WCLE IKFLNRNAYIMIAIYG+NFC SAK+AF LLMRN+++ Sbjct: 542 RTQNTLSKFLQCCLRCCFWCLENAIKFLNRNAYIMIAIYGRNFCRSAKDAFNLLMRNVLK 601 Query: 588 VVVLDKVTDLLLFFGKLLVVGGVGVLSFFFFSGRIPGLGKDFKSPHLNYYWLPIMTSILG 647 V V D+VT +LF GKLLV G +GVL+F FF+ R+P + + S LNYYW+P++T I G Sbjct: 602 VAVTDEVTYFVLFLGKLLVAGSIGVLAFLFFTQRLPVIAQGPAS--LNYYWVPLLTVIFG 659 Query: 648 AYVIASGFFSVFGMCVDTLFLCFLEDLERNNGSLDRPYYMSKSLLKILGKKNEAPPDNKK 707 +Y+IA GFFSV+ MCV+T+F+CFLEDLERN+GS RPYY+S+ LLKI ++N P +K Sbjct: 660 SYLIAHGFFSVYAMCVETIFICFLEDLERNDGSTARPYYVSQPLLKIFQEEN---PQTRK 716 Query: 708 R 708 + Sbjct: 717 Q 717 >gi|194239631 solute carrier family 44, member 5 isoform A [Homo sapiens] Length = 719 Score = 692 bits (1786), Expect = 0.0 Identities = 334/720 (46%), Positives = 484/720 (67%), Gaps = 34/720 (4%) Query: 9 DDEAYGKPVKYDPSFRGPIKNRSCTDVICCVLFLLFILGYIVVGIVAWLYGDPRQVLYPR 68 ++E +G P YDP F+GP+ NRSCTDV+CC++FLL I+GYIV+G+VAW++GDPR+ YP Sbjct: 13 EEEDFGDPRTYDPDFKGPVANRSCTDVLCCMIFLLCIIGYIVLGLVAWVHGDPRRAAYPT 72 Query: 69 NSTGAYCGMG--ENKDKPYLLYFNIFSCILSSNIISVAENGLQCPTPQVCVSSCPEDPWT 126 +S G +CG N++K L YFN+ C S +++ LQCPT Q+CVS CPE T Sbjct: 73 DSQGHFCGQKGTPNENKTILFYFNLLRCTSPSVLLN-----LQCPTTQICVSKCPEKFLT 127 Query: 127 VGKNEFSQTVGEVFYTKNRNFCLPGVPWNMTVITSLQQELCPSFLLPSAPALGRCFPWTN 186 + + T + ++ R FC ++ L + CP+ + PS P L RCFP + Sbjct: 128 YVEMQLLYTKDKSYWEDYRQFCKTTAKPVKSLTQLLLDDDCPTAIFPSKPFLQRCFPDFS 187 Query: 187 VTPPALPGITNDTTIQQG-------------ISGLIDSLNARDISVKIFEDFAQSWYWIL 233 L I + Q G +G+ L+A+ + +K+FED+A++WYWIL Sbjct: 188 TKNGTLT-IGSKMMFQDGNGGTRSVVELGIAANGINKLLDAKSLGLKVFEDYARTWYWIL 246 Query: 234 VALGVALVLSLLFILLLRLVAGPLVLVLILGVLGVLAYGIYYCWEEYRVLRDKGAS---I 290 + L +A+VLS +F++LLR +AG L V ++GV+G++ YGI++C+++Y L+++ +S I Sbjct: 247 IGLTIAMVLSWIFLILLRFIAGCLFWVFMIGVIGIIGYGIWHCYQQYTNLQERPSSVLTI 306 Query: 291 SQLGFTTNLSAYQSVQETWLAALIVLAVLEAILLLMLIFLRQRIRIAIALLKEASKAVGQ 350 +G TN+S Y +Q+TW +I+L ++E I++LMLIFLR RIR+AI LLKE SKA+G Sbjct: 307 YDIGIQTNISMYFELQQTWFTFMIILCIIEVIVILMLIFLRNRIRVAIILLKEGSKAIGY 366 Query: 351 MMSTMFYPLVTFVLLLICIAYWAMTALYLATSGQPQYVLWASNISSPGCEKVPINTSCNP 410 + ST+ YP +TF+LL ICI YW +TA++LATSG P Y + +PG + N +C+P Sbjct: 367 VPSTLVYPALTFILLSICICYWVVTAVFLATSGVPVY-----KVIAPGGHCIHENQTCDP 421 Query: 411 ---TAHLVNSSCPGLMCVFQGYSSKGLIQRSVFNLQIYGVLGLFWTLNWVLALGQCVLAG 467 + +CPG +C F Y K L + + +Y + W +N+V+ALGQC LAG Sbjct: 422 EIFNTTEIAKACPGALCNFAFYGGKSLYHQYIPTFHVYNLFVFLWLINFVIALGQCALAG 481 Query: 468 AFASFYWAFHKPQDIPTFPLISAFIRTLRYHTGSLAFGALILTLVQIARVILEYIDHKLR 527 AFA++YWA KP DIP +PL +AF R +RYHTGSLAFG+LI+ L+Q+ +++LEY+DH+L+ Sbjct: 482 AFATYYWAMKKPDDIPRYPLFTAFGRAIRYHTGSLAFGSLIIALIQMFKIVLEYLDHRLK 541 Query: 528 GVQNPVARCIMCCFKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNIVR 587 QN +++ + CC +CC WCLE IKFLNRNAYIMIAIYG+NFC SAK+AF LLMRN+++ Sbjct: 542 RTQNTLSKFLQCCLRCCFWCLENAIKFLNRNAYIMIAIYGRNFCRSAKDAFNLLMRNVLK 601 Query: 588 VVVLDKVTDLLLFFGKLLVVGGVGVLSFFFFSGRIPGLGKDFKSPHLNYYWLPIMTSILG 647 V V D+VT +LF GKLLV G +GVL+F FF+ R+P + + S LNYYW+P++T I G Sbjct: 602 VAVTDEVTYFVLFLGKLLVAGSIGVLAFLFFTQRLPVIAQGPAS--LNYYWVPLLTVIFG 659 Query: 648 AYVIASGFFSVFGMCVDTLFLCFLEDLERNNGSLDRPYYMSKSLLKILGKKNEAPPDNKK 707 +Y+IA GFFSV+ MCV+T+F+CF EDLERN+GS ++PY+++ +L IL KK P K+ Sbjct: 660 SYLIAHGFFSVYAMCVETIFICFCEDLERNDGSTEKPYFVTPNLHGILIKKQLVPQKQKE 719 >gi|18034692 CDW92 antigen [Homo sapiens] Length = 657 Score = 250 bits (639), Expect = 3e-66 Identities = 197/699 (28%), Positives = 328/699 (46%), Gaps = 109/699 (15%) Query: 26 PIKNRSCTDVICCVLFLLFILGYIVVGIVAWLYGDPRQVLYPRNSTGAYCGMGENK---- 81 P+++RSCTD+ +LF+LF +G + + G +++ +S G CG K Sbjct: 20 PLEDRSCTDIPWLLLFILFCIGMGFICGFSIATGAAARLVSGYDSYGNICGQKNTKLEAI 79 Query: 82 --------DKPYLLYFNIFSC-ILSSNIISVAENGLQCPTPQVCVSSCPEDPWTVGKN-- 130 + Y+ + + + +++ I SVA +CV++CP + Sbjct: 80 PNSGMDHTQRKYVFFLDPCNLDLINRKIKSVA----------LCVAACPRQELKTLSDVQ 129 Query: 131 EFSQTVGEVFYTKNRNFCLPGVPWNMTVITSLQQELCPSFLLPSA---PALGRCFPWTNV 187 +F++ G + N P T + LCP +P++ P RC P Sbjct: 130 KFAEINGSALCSYNLK------PSEYTT-SPKSSVLCPKLPVPASAPIPFFHRCAP---- 178 Query: 188 TPPALPGITNDTTIQQGISGLIDSLNARDISVKIFEDFAQSWYWILVALGVALVLSLLFI 247 N + + LI ++ + ++ S IL ++LVLS++ + Sbjct: 179 --------VNISCYAKFAEALITFVSDNSVLHRLISGVMTSKEIILGLCLLSLVLSMILM 230 Query: 248 LLLRLVAGPLVLVL-ILGVLGVLAYGIYYCWEEYRVLRDKGASISQLGFTTNLSAYQSVQ 306 +++R ++ LV +L IL +LG L G W Y R T + Sbjct: 231 VIIRYISRVLVWILTILVILGSLG-GTGVLWWLYAKQRRSPKE-------TVTPEQLQIA 282 Query: 307 ETWLAALIVLA----VLEAILLLMLIFLRQRIRIAIALLKEASKAVGQMMSTMFYPLVTF 362 E L AL++ A V IL L+++ +R+R+ + IAL A K + +F P TF Sbjct: 283 EDNLRALLIYAISATVFTVILFLIMLVMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTF 342 Query: 363 VLLLICIAYWAMTALYLATSGQPQYVLWASNISSPGCEKVPINTSCNPTAHLVNSSCPGL 422 L++ YW MT L+L T+G P + G Sbjct: 343 FALVLFWVYWIMTLLFLGTTGSPVQ-------NEQG------------------------ 371 Query: 423 MCVFQGYSSKGLIQRSVFNLQIYGVLGLFWTLNWVLALGQCVLAGAFASFYWAFHKPQDI 482 F + G +Q + Y V+GL W ++LA Q +AGA ++Y+ K +++ Sbjct: 372 ---FVEFKISGPLQYMWW----YHVVGLIWISEFILACQQMTVAGAVVTYYFTRDK-RNL 423 Query: 483 PTFPLISAFIRTLRYHTGSLAFGALILTLVQIARVILEYIDHKLRGVQNPVARCIMCCFK 542 P P++++ R +RYH G++A G+ I+TLV+I R+IL YI +L+G +N ARC++ Sbjct: 424 PFTPILASVNRLIRYHLGTVAKGSFIITLVKIPRMILMYIHSQLKGKENACARCVLKSCI 483 Query: 543 CCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNIVRVVVLDKVTDLLLFFG 602 CCLWCLEK + +LN+NAY AI NFC SAK+AF++L+ N +RV ++ V D +LF G Sbjct: 484 CCLWCLEKCLNYLNQNAYTATAINSTNFCTSAKDAFVILVENALRVATINTVGDFMLFLG 543 Query: 603 KLLVVGGVGVLSFFFFSGRIPGLGKDFKSPHLNYYWLPIMTSILGAYVIASGFFSVFGMC 662 K+L+V G+ + + +D+ + LP++ L A+++A F S++ M Sbjct: 544 KVLIVCSTGLAGIMLLNYQ-----QDY-----TVWVLPLIIVCLFAFLVAHCFLSIYEMV 593 Query: 663 VDTLFLCFLEDLERNNGSLDRPYYMSKSLLKILGKKNEA 701 VD LFLCF D + N+GS R +YM K L++ + +A Sbjct: 594 VDVLFLCFAIDTKYNDGSPGREFYMDKVLMEFVENSRKA 632 >gi|166235173 solute carrier family 44, member 3 isoform 1 [Homo sapiens] Length = 653 Score = 218 bits (556), Expect = 1e-56 Identities = 180/683 (26%), Positives = 303/683 (44%), Gaps = 94/683 (13%) Query: 30 RSCTDVICCVLFLLFILGYIVVGIVAWLYGDPRQVLYPRNSTGAYCGMGENKDKPYLLY- 88 R CTD LF LF G + + + + G ++L+ +S G CG + + L Sbjct: 27 RKCTDTAWLFLFFLFWTGLVFIMGYSVVAGAAGRLLFGYDSFGNMCGKKNSPVEGAPLSG 86 Query: 89 --FNIFSCILSSNIISVAENGLQCPTPQVCVSSCPEDPWTVGKNE--FSQTVGEVFYTKN 144 + + N ++ G Q +CVS+CPE+ + F+ T G + Sbjct: 87 QDMTLKKHVFFMNSCNLEVKGTQLNRMALCVSNCPEEQLDSLEEVQFFANTSGSFLCVYS 146 Query: 145 RNFCLPGVPWNMTVITSLQQELCPSFLLP---SAPALGRCFPWTNVTPPALPGIT-NDT- 199 N +N T + LCP +P S P RC P T + ND Sbjct: 147 LN------SFNYTH-SPKADSLCPRLPVPPSKSFPLFNRCVPQTPECYSLFASVLINDVD 199 Query: 200 TIQQGISGLIDSLNARDISVKIFEDFAQSWYWILVALGVALVLSLLFILLLRLVAGPLVL 259 T+ + +SG+ ++ RD + + ++AL ++L + F + L+ + Sbjct: 200 TLHRILSGI---MSGRDTILGL----------CILALALSLAMMFTFRFITTLLVHIFIS 246 Query: 260 VLILGVLGVLAYGIYYCWEEYRVLRDKGASISQLGFTTNLSAYQSVQETWLAALIVLAVL 319 ++ILG+L V G+ + W Y D + L + + L IV + Sbjct: 247 LVILGLLFVC--GVLW-WLYYDYTND---------LSIELDTERENMKCVLGFAIVSTGI 294 Query: 320 EAILLLMLIFLRQRIRIAIALLKEASKAVGQMMSTMFYPLVTFVLLLICIAYWAMTALYL 379 A+LL+++ LR+RI++ + L + +KA+ +F PL TF +L+ W L L Sbjct: 295 TAVLLVLIFVLRKRIKLTVELFQITNKAISSAPFLLFQPLWTFAILIFFWVLWVAVLLSL 354 Query: 380 ATSGQPQYVLWASNISSPGCEKVPINTSCNPTAHLVNSSCPGLMCVFQGYSSKGLIQRSV 439 T+G Q V +G + + Sbjct: 355 GTAGAAQ--------------------------------------VMEGGQVEYKPLSGI 376 Query: 440 FNLQIYGVLGLFWTLNWVLALGQCVLAGAFASFYWAFHKPQDIPTFPLISAFIRTLRYHT 499 + Y ++GL WT ++LA Q +AGA + Y+ K D P P++S+ YH Sbjct: 377 RYMWSYHLIGLIWTSEFILACQQMTIAGAVVTCYFNRSK-NDPPDHPILSSLSILFFYHQ 435 Query: 500 GSLAFGALILTLVQIARVILEYIDHKLRGVQN-PVARCIMCCFKCCLWCLEKFIKFLNRN 558 G++ G+ ++++V+I R+I+ Y+ + L+ Q+ ++R + C CC WCL+K++ LN+N Sbjct: 436 GTVVKGSFLISVVRIPRIIVMYMQNALKEQQHGALSRYLFRCCYCCFWCLDKYLLHLNQN 495 Query: 559 AYIMIAIYGKNFCVSAKNAFMLLMRNIVRVVVLDKVTDLLLFFGKLLVVGGVGVLSFFFF 618 AY AI G +FC SAK+AF +L +N ++ D ++F GK+LVV F F Sbjct: 496 AYTTTAINGTDFCTSAKDAFKILSKNSSHFTSINCFGDFIIFLGKVLVV------CFTVF 549 Query: 619 SGRIPGLGKDFKSPHLNYYW-LPIMTSILGAYVIASGFFSVFGMCVDTLFLCFLEDLERN 677 G + F W +P++ AY++A F SVF +D LFLCF DLE N Sbjct: 550 GGLMA-----FNYNRAFQVWAVPLLLVAFFAYLVAHSFLSVFETVLDALFLCFAVDLETN 604 Query: 678 NGSLDRPYYMSKSLLKILGKKNE 700 +GS ++PY+M + L + + N+ Sbjct: 605 DGSSEKPYFMDQEFLSFVKRSNK 627 >gi|166235171 solute carrier family 44, member 3 isoform 2 [Homo sapiens] Length = 605 Score = 206 bits (525), Expect = 5e-53 Identities = 175/667 (26%), Positives = 295/667 (44%), Gaps = 100/667 (14%) Query: 46 LGYIVVGIVAWLYGDPRQVLYPRNSTGAYCGMGENKDKPYLLY---FNIFSCILSSNIIS 102 +GY VV G ++L+ +S G CG + + L + + N + Sbjct: 1 MGYSVVA------GAAGRLLFGYDSFGNMCGKKNSPVEGAPLSGQDMTLKKHVFFMNSCN 54 Query: 103 VAENGLQCPTPQVCVSSCPEDPWTVGKNE--FSQTVGEVFYTKNRNFCLPGVPWNMTVIT 160 + G Q +CVS+CPE+ + F+ T G + N +N T + Sbjct: 55 LEVKGTQLNRMALCVSNCPEEQLDSLEEVQFFANTSGSFLCVYSLN------SFNYTH-S 107 Query: 161 SLQQELCPSFLLP---SAPALGRCFPWTNVTPPALPGIT-NDT-TIQQGISGLIDSLNAR 215 LCP +P S P RC P T + ND T+ + +SG+ ++ R Sbjct: 108 PKADSLCPRLPVPPSKSFPLFNRCVPQTPECYSLFASVLINDVDTLHRILSGI---MSGR 164 Query: 216 DISVKIFEDFAQSWYWILVALGVALVLSLLFILLLRLVAGPLVLVLILGVLGVLAYGIYY 275 D + + ++AL ++L + F + L+ + ++ILG+L V G+ + Sbjct: 165 DTILGL----------CILALALSLAMMFTFRFITTLLVHIFISLVILGLLFVC--GVLW 212 Query: 276 CWEEYRVLRDKGASISQLGFTTNLSAYQSVQETWLAALIVLAVLEAILLLMLIFLRQRIR 335 W Y D + L + + L IV + A+LL+++ LR+RI+ Sbjct: 213 -WLYYDYTND---------LSIELDTERENMKCVLGFAIVSTGITAVLLVLIFVLRKRIK 262 Query: 336 IAIALLKEASKAVGQMMSTMFYPLVTFVLLLICIAYWAMTALYLATSGQPQYVLWASNIS 395 + + L + +KA+ +F PL TF +L+ W L L T+G Q Sbjct: 263 LTVELFQITNKAISSAPFLLFQPLWTFAILIFFWVLWVAVLLSLGTAGAAQ--------- 313 Query: 396 SPGCEKVPINTSCNPTAHLVNSSCPGLMCVFQGYSSKGLIQRSVFNLQIYGVLGLFWTLN 455 V +G + + + Y ++GL WT Sbjct: 314 -----------------------------VMEGGQVEYKPLSGIRYMWSYHLIGLIWTSE 344 Query: 456 WVLALGQCVLAGAFASFYWAFHKPQDIPTFPLISAFIRTLRYHTGSLAFGALILTLVQIA 515 ++LA Q +AGA + Y+ K D P P++S+ YH G++ G+ ++++V+I Sbjct: 345 FILACQQMTIAGAVVTCYFNRSK-NDPPDHPILSSLSILFFYHQGTVVKGSFLISVVRIP 403 Query: 516 RVILEYIDHKLRGVQN-PVARCIMCCFKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSA 574 R+I+ Y+ + L+ Q+ ++R + C CC WCL+K++ LN+NAY AI G +FC SA Sbjct: 404 RIIVMYMQNALKEQQHGALSRYLFRCCYCCFWCLDKYLLHLNQNAYTTTAINGTDFCTSA 463 Query: 575 KNAFMLLMRNIVRVVVLDKVTDLLLFFGKLLVVGGVGVLSFFFFSGRIPGLGKDFKSPHL 634 K+AF +L +N ++ D ++F GK+LVV F F G + F Sbjct: 464 KDAFKILSKNSSHFTSINCFGDFIIFLGKVLVV------CFTVFGGLMA-----FNYNRA 512 Query: 635 NYYW-LPIMTSILGAYVIASGFFSVFGMCVDTLFLCFLEDLERNNGSLDRPYYMSKSLLK 693 W +P++ AY++A F SVF +D LFLCF DLE N+GS ++PY+M + L Sbjct: 513 FQVWAVPLLLVAFFAYLVAHSFLSVFETVLDALFLCFAVDLETNDGSSEKPYFMDQEFLS 572 Query: 694 ILGKKNE 700 + + N+ Sbjct: 573 FVKRSNK 579 >gi|21264580 tetraspan 2 [Homo sapiens] Length = 221 Score = 36.2 bits (82), Expect = 0.11 Identities = 30/84 (35%), Positives = 39/84 (46%), Gaps = 10/84 (11%) Query: 597 LLLFFGKLLVVGGVGVLSF---FFFSGRIPGLGKDFKSPHLNYYWLPIMTSILGAYVIAS 653 LLL F L + G V++F F F G I L + KSP Y L ++ GA ++A Sbjct: 14 LLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYVLVG-AGALMMAV 72 Query: 654 GFFSVFG-----MCV-DTLFLCFL 671 GFF G CV + F C L Sbjct: 73 GFFGCCGAMRESQCVLGSFFTCLL 96 >gi|4502827 cholinergic receptor, nicotinic, alpha 4 subunit precursor [Homo sapiens] Length = 627 Score = 32.7 bits (73), Expect = 1.2 Identities = 28/101 (27%), Positives = 44/101 (43%), Gaps = 20/101 (19%) Query: 168 PSFLLPSAPALGRCFPWTNVTPPALPGITNDTTIQQGISGLIDSLNARDISVKIFEDFAQ 227 PS + PSA R T PP LP T +G+ + D L A D + ED Sbjct: 537 PSSVSPSATVKTRS---TKAPPPHLPLSPALTRAVEGVQYIADHLKAEDTDFSVKED--- 590 Query: 228 SWYWILVALGVALVLSLLFILLLRLVAGPLVLVLILGVLGV 268 W + VA+V+ +F+ + ++V +LG +G+ Sbjct: 591 -WKY------VAMVIDRIFLWM-------FIIVCLLGTVGL 617 >gi|157388902 semaphorin 4C [Homo sapiens] Length = 833 Score = 32.3 bits (72), Expect = 1.6 Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 23/99 (23%) Query: 272 GIYYCWEEYRVLRDKGASISQLGFTTNLSAYQSVQE-----------TWLAALIVLAVLE 320 G Y+C+ E ++GA ++ G+ + A SV WLA ++ L + Sbjct: 623 GAYHCFSE-----EQGARLAAEGYLVAVVAGPSVTLEARAPLENLGLVWLA-VVALGAVC 676 Query: 321 AILLLMLIFLRQRIRIAIALLKEASKAVGQMMSTMFYPL 359 +LLL+++ LR+R+R +E K T+ YPL Sbjct: 677 LVLLLLVLSLRRRLR------EELEKGAKATERTLVYPL 709 >gi|4502187 aquaporin 7 [Homo sapiens] Length = 342 Score = 30.4 bits (67), Expect = 5.9 Identities = 12/29 (41%), Positives = 19/29 (65%) Query: 622 IPGLGKDFKSPHLNYYWLPIMTSILGAYV 650 I G GK S N++W+P++ +LGAY+ Sbjct: 239 IAGWGKQVFSNGENWWWVPVVAPLLGAYL 267 >gi|21729876 ATP-binding cassette, sub-family C, member 11 isoform b [Homo sapiens] Length = 1344 Score = 30.0 bits (66), Expect = 7.7 Identities = 18/72 (25%), Positives = 32/72 (44%), Gaps = 1/72 (1%) Query: 25 GPIKNRSCTDVICCVLFLLFILGYIV-VGIVAWLYGDPRQVLYPRNSTGAYCGMGENKDK 83 GP+ +C ++ C + FI+GY + I+ +L P V R + A E D+ Sbjct: 278 GPLVLITCASLVICSISSYFIIGYTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQ 337 Query: 84 PYLLYFNIFSCI 95 + + +CI Sbjct: 338 RIRVTSEVLTCI 349 >gi|21729873 ATP-binding cassette, sub-family C, member 11 isoform a [Homo sapiens] Length = 1382 Score = 30.0 bits (66), Expect = 7.7 Identities = 18/72 (25%), Positives = 32/72 (44%), Gaps = 1/72 (1%) Query: 25 GPIKNRSCTDVICCVLFLLFILGYIV-VGIVAWLYGDPRQVLYPRNSTGAYCGMGENKDK 83 GP+ +C ++ C + FI+GY + I+ +L P V R + A E D+ Sbjct: 278 GPLVLITCASLVICSISSYFIIGYTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQ 337 Query: 84 PYLLYFNIFSCI 95 + + +CI Sbjct: 338 RIRVTSEVLTCI 349 >gi|15149474 ATP-binding cassette, sub-family C, member 11 isoform a [Homo sapiens] Length = 1382 Score = 30.0 bits (66), Expect = 7.7 Identities = 18/72 (25%), Positives = 32/72 (44%), Gaps = 1/72 (1%) Query: 25 GPIKNRSCTDVICCVLFLLFILGYIV-VGIVAWLYGDPRQVLYPRNSTGAYCGMGENKDK 83 GP+ +C ++ C + FI+GY + I+ +L P V R + A E D+ Sbjct: 278 GPLVLITCASLVICSISSYFIIGYTAFIAILCYLLVFPLAVFMTRMAVKAQHHTSEVSDQ 337 Query: 84 PYLLYFNIFSCI 95 + + +CI Sbjct: 338 RIRVTSEVLTCI 349 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.328 0.143 0.457 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 26,699,243 Number of Sequences: 37866 Number of extensions: 1190123 Number of successful extensions: 3956 Number of sequences better than 10.0: 15 Number of HSP's better than 10.0 without gapping: 9 Number of HSP's successfully gapped in prelim test: 6 Number of HSP's that attempted gapping in prelim test: 3893 Number of HSP's gapped (non-prelim): 22 length of query: 710 length of database: 18,247,518 effective HSP length: 109 effective length of query: 601 effective length of database: 14,120,124 effective search space: 8486194524 effective search space used: 8486194524 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.