Search of human proteins with 148539872

Search of human proteins with 148539872

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148539872 acetyl-Coenzyme A acetyltransferase 2 [Homo
sapiens]
         (397 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148539872 acetyl-Coenzyme A acetyltransferase 2 [Homo sapiens]     781   0.0  
gi|4557237 acetyl-Coenzyme A acetyltransferase 1 precursor [Homo...   300   1e-81
gi|167614485 acetyl-coenzyme A acyltransferase 2 [Homo sapiens]       295   5e-80
gi|4501853 acetyl-Coenzyme A acyltransferase 1 isoform a [Homo s...   246   3e-65
gi|4504327 mitochondrial trifunctional protein, beta subunit pre...   166   3e-41
gi|194353979 acetyl-Coenzyme A acyltransferase 1 isoform b [Homo...   102   8e-22
gi|19923233 sterol carrier protein 2 isoform 1 proprotein [Homo ...    59   6e-09
gi|55956775 sterol carrier protein 2 isoform 2 [Homo sapiens]          45   1e-04
gi|154090979 hypothetical protein LOC57481 [Homo sapiens]              30   5.0  
gi|56549696 E1A binding protein p400 [Homo sapiens]                    29   6.5  
gi|224926824 SH2B adaptor protein 1 isoform 2 [Homo sapiens]           29   8.5  
gi|110349719 titin isoform N2-A [Homo sapiens]                         29   8.5  
gi|110349717 titin isoform novex-2 [Homo sapiens]                      29   8.5  
gi|110349713 titin isoform novex-1 [Homo sapiens]                      29   8.5  
gi|110349715 titin isoform N2-B [Homo sapiens]                         29   8.5  
gi|224926830 SH2B adaptor protein 1 isoform 3 [Homo sapiens]           29   8.5  
gi|224926828 SH2B adaptor protein 1 isoform 2 [Homo sapiens]           29   8.5  
gi|224926826 SH2B adaptor protein 1 isoform 1 [Homo sapiens]           29   8.5  
gi|224926822 SH2B adaptor protein 1 isoform 2 [Homo sapiens]           29   8.5  
gi|149589021 doublecortin-like kinase 3 [Homo sapiens]                 29   8.5  

>gi|148539872 acetyl-Coenzyme A acetyltransferase 2 [Homo sapiens]
          Length = 397

 Score =  781 bits (2018), Expect = 0.0
 Identities = 397/397 (100%), Positives = 397/397 (100%)

Query: 1   MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHV 60
           MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHV
Sbjct: 1   MNAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHV 60

Query: 61  LAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGME 120
           LAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGME
Sbjct: 61  LAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGME 120

Query: 121 NMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDK 180
           NMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDK
Sbjct: 121 NMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDK 180

Query: 181 VAVLSQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLT 240
           VAVLSQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLT
Sbjct: 181 VAVLSQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLT 240

Query: 241 DGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPA 300
           DGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPA
Sbjct: 241 DGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPA 300

Query: 301 IKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGC 360
           IKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGC
Sbjct: 301 IKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGC 360

Query: 361 RILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE 397
           RILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE
Sbjct: 361 RILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE 397


>gi|4557237 acetyl-Coenzyme A acetyltransferase 1 precursor [Homo
           sapiens]
          Length = 427

 Score =  300 bits (769), Expect = 1e-81
 Identities = 170/390 (43%), Positives = 243/390 (62%), Gaps = 6/390 (1%)

Query: 8   VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67
           VVIVSA RT IGSF G+L+ +P   LGS  I+  +++A +  E+V E   G+VL  G GQ
Sbjct: 42  VVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQ 101

Query: 68  NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPH 127
            P RQA +GAG+P S P  +   +C SG+KA+ +A QS+  G   ++VAGGME+MS  P+
Sbjct: 102 APTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPY 161

Query: 128 LAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLSQN 187
           +   R     G + L D I+ DGLTD ++  HMG  AEN AKK  ++R +QD  A+ S  
Sbjct: 162 VMN-RGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYT 220

Query: 188 RTENAQKAGHFDKEIVPVLVSTR-KGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTV 246
           R++ A +AG F  E++PV V+ + +  + VK DE  +   +   + KLK  F  +  GTV
Sbjct: 221 RSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKR-VDFSKVPKLKTVFQKEN-GTV 278

Query: 247 TPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVT 306
           T ANAS +NDGAAA+VLM    A +  +TPLARIV+++   VEP    I P+ A    + 
Sbjct: 279 TAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLK 338

Query: 307 KAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTL 366
             G   ED+ ++E+NEAF+ V  A +K L ++P+KVNI GGA++LGHP+G SG RI+  L
Sbjct: 339 DVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHL 398

Query: 367 LHTLERMGRSRGVAALCIGGGMGIAMCVQR 396
            H L++     G+A++C GGG   AM +Q+
Sbjct: 399 THALKQ--GEYGLASICNGGGGASAMLIQK 426


>gi|167614485 acetyl-coenzyme A acyltransferase 2 [Homo sapiens]
          Length = 397

 Score =  295 bits (755), Expect = 5e-80
 Identities = 166/390 (42%), Positives = 229/390 (58%), Gaps = 4/390 (1%)

Query: 8   VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67
           V +V+A RT  G++ G L      DL     K  L    V+PE V  VI G+VL +    
Sbjct: 7   VFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDA 66

Query: 68  NPV-RQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAP 126
             + R   +  GIP   PA +   +CGSG +++    Q I + ++ +V+ GG E+MS+AP
Sbjct: 67  IYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAP 126

Query: 127 H-LAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLS 185
           + +  +R G K+G     +  L   LTD      M +TAEN+A K ++SRE+ DK A+ S
Sbjct: 127 YCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQS 186

Query: 186 QNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGT 245
           Q R + A  AG+F+ E+ P+ V T+KG   ++ DE  R  + +E + KL P F  DGT  
Sbjct: 187 QQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDGT-- 244

Query: 246 VTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAV 305
           VT  NASG+ DGA AV++  +    K   TPLARIV +   G +PSIMGIGP+PAI  A+
Sbjct: 245 VTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGAL 304

Query: 306 TKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVT 365
            KAG SL+D+D+ E+NEAFA    A+ + L L+  K N+ GGAIALGHPLG SG RI   
Sbjct: 305 KKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITAH 364

Query: 366 LLHTLERMGRSRGVAALCIGGGMGIAMCVQ 395
           L+H L R G    V + CIGGG GIA+ +Q
Sbjct: 365 LVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394


>gi|4501853 acetyl-Coenzyme A acyltransferase 1 isoform a [Homo
           sapiens]
          Length = 424

 Score =  246 bits (628), Expect = 3e-65
 Identities = 163/396 (41%), Positives = 224/396 (56%), Gaps = 19/396 (4%)

Query: 3   AGSDPVVIVSAARTII-GSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVL 61
           A +  VV+V   RT I  +  G        +L S V+  VLK   + PE + ++  G+VL
Sbjct: 33  ASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVL 92

Query: 62  AAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMEN 121
             G G    R A   + IP +VP  +    C SGL+AV      I  G   I +A G+E+
Sbjct: 93  QPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVES 152

Query: 122 MSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKV 181
           MS A          ++ E       L            MGIT+ENVA+++ +SRE QD  
Sbjct: 153 MSLADRGNPGNITSRLMEKEKARDCLIP----------MGITSENVAERFGISREKQDTF 202

Query: 182 AVLSQNRTENAQKAGHFDKEIVPVLVSTR-----KGLIEVKTDEFPRHGSNIEAMSKLKP 236
           A+ SQ +   AQ  G F  EIVPV  +       K  I V  DE  R  + +E ++KLKP
Sbjct: 203 ALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKP 262

Query: 237 YFLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIG 296
            F  DG+   T  N+S ++DGAAA++L ++S+A++ GL  L  + S++ VGV P IMGIG
Sbjct: 263 AFKKDGS--TTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIG 320

Query: 297 PIPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLG 356
           P  AI  A+ KAG ++ DVDIFEINEAFA+ +A  V++L L PEKVN  GGA+ALGHPLG
Sbjct: 321 PAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLG 380

Query: 357 ASGCRILVTLLHTLERMG-RSRGVAALCIGGGMGIA 391
            +G R ++TLL+ L+R G R+ GV ++CIG GMG A
Sbjct: 381 CTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAA 416


>gi|4504327 mitochondrial trifunctional protein, beta subunit
           precursor [Homo sapiens]
          Length = 474

 Score =  166 bits (420), Expect = 3e-41
 Identities = 131/423 (30%), Positives = 207/423 (48%), Gaps = 41/423 (9%)

Query: 8   VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67
           VV+V   RT       +   +   DL    +  +L R +V  E V  +IFG V+      
Sbjct: 54  VVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTS 113

Query: 68  NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAP- 126
           N  R+A++GAG     PA +  M C S  +A+   V  I  G   ++VAGG+E MS  P 
Sbjct: 114 NVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPI 173

Query: 127 -HLAYLRTGV----KIGEMPLTDSILCD-----------GLTDAFHNCHMGITAENVAKK 170
            H   +R  +    K   M    S++              +++   +  MG +A+ +A  
Sbjct: 174 RHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAA 233

Query: 171 WQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEA 230
           + VSR +QD+ A+ S +  + AQ  G    ++VP  V  +    +  T +     S++E 
Sbjct: 234 FAVSRLEQDEYALRSHSLAKKAQDEGLLS-DVVPFKVPGK----DTVTKDNGIRPSSLEQ 288

Query: 231 MSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEP 290
           M+KLKP F+    GTVT AN+S + DGA+A+++M + +A   G  P A +  +  V  +P
Sbjct: 289 MAKLKPAFIKP-YGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDP 347

Query: 291 SI-MGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVK---------------- 333
              + +GP  A  + + KAG ++ D+D FE +EAF+    A  K                
Sbjct: 348 KDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKT 407

Query: 334 ELGLNP-EKVNIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAM 392
           ++GL P EK N  GG+++LGHP GA+GCR+++   + L + G   G+ A C  GG G AM
Sbjct: 408 KVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAM 467

Query: 393 CVQ 395
            V+
Sbjct: 468 IVE 470


>gi|194353979 acetyl-Coenzyme A acyltransferase 1 isoform b [Homo
           sapiens]
          Length = 331

 Score =  102 bits (253), Expect = 8e-22
 Identities = 59/110 (53%), Positives = 79/110 (71%), Gaps = 5/110 (4%)

Query: 287 GVEPS--IMGIGPI-PAIKQ-AVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKV 342
           G+ PS  + G+  + PA K+   T AG ++ DVDIFEINEAFA+ +A  V++L L PEKV
Sbjct: 214 GIRPSTTMEGLAKLKPAFKKDGSTTAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKV 273

Query: 343 NIEGGAIALGHPLGASGCRILVTLLHTLERMG-RSRGVAALCIGGGMGIA 391
           N  GGA+ALGHPLG +G R ++TLL+ L+R G R+ GV ++CIG GMG A
Sbjct: 274 NPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAA 323



 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 88/292 (30%), Positives = 124/292 (42%), Gaps = 55/292 (18%)

Query: 3   AGSDPVVIVSAARTII-GSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVL 61
           A +  VV+V   RT I  +  G        +L S V+  VLK   + PE + ++  G+VL
Sbjct: 33  ASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVL 92

Query: 62  AAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMEN 121
             G G    R A   + IP +VP  +    C SGL+AV               +AGG+ N
Sbjct: 93  QPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVAS-------------IAGGIRN 139

Query: 122 MSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKV 181
                                       G  D    C  GIT+ENVA+++ +SRE QD  
Sbjct: 140 ----------------------------GSYDIGMAC--GITSENVAERFGISREKQDTF 169

Query: 182 AVLSQNRTENAQKAGHFDKEIVPVLVSTR-----KGLIEVKTDEFPRHGSNIEAMSKLKP 236
           A+ SQ +   AQ  G F  EIVPV  +       K  I V  DE  R  + +E ++KLKP
Sbjct: 170 ALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKP 229

Query: 237 YFLTDGTG----TVTPANASGINDGAA--AVVLMKKSEADKRGLTPLARIVS 282
            F  DG+     TV+  +   IN+  A  A   ++K       + PL   V+
Sbjct: 230 AFKKDGSTTAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVA 281


>gi|19923233 sterol carrier protein 2 isoform 1 proprotein [Homo
           sapiens]
          Length = 547

 Score = 59.3 bits (142), Expect = 6e-09
 Identities = 85/360 (23%), Positives = 137/360 (38%), Gaps = 67/360 (18%)

Query: 32  DLGSTVIKEVLKRATVAPEDVSEVIFGHVLA-AGCGQNPVRQASVGAGIPYSVPAWSCQM 90
           DL     K+ L  A +    V +   G+V   + CGQ  +  +    GIP      +   
Sbjct: 37  DLAEEAGKKALADAQIPYSAVDQACVGYVFGDSTCGQRAIYHSLGMTGIPII----NVNN 92

Query: 91  ICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDG 150
            C +G  A+ +A Q I  G +  V+A G E MSK         G+K  +  +      D 
Sbjct: 93  NCATGSTALFMARQLIQGGVAECVLALGFEKMSKGS------LGIKFSDRTIPTDKHVDL 146

Query: 151 LTDAFHNCHMGITAENVAKKW--QVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVS 208
           L + +     G++A  VA +      +E  +K             K  HF K    +   
Sbjct: 147 LINKY-----GLSAHPVAPQMFGYAGKEHMEKYGT----------KIEHFAK----IGWK 187

Query: 209 TRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKKSE 268
             K  +     +F    S  E M+  + +        +T       +DGAAA +L  ++ 
Sbjct: 188 NHKHSVNNPYSQFQDEYSLDEVMASKEVFDF------LTILQCCPTSDGAAAAILASEAF 241

Query: 269 ADKRGLTPLARIVSWSQVGV-------EPSIMGIGPIPAIKQAVTK----AGWSLEDVDI 317
             K GL   A  +   ++         E SI+ +      K+A  K    +G +  D+D+
Sbjct: 242 VQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDIDV 301

Query: 318 FEINEAFAAVSAAIVKELGLNPE------------------KVNIEGGAIALGHPLGASG 359
            E+++ F+       + LGL PE                   +N  GG I+ GHPLGA+G
Sbjct: 302 IELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPSGGLISKGHPLGATG 361


>gi|55956775 sterol carrier protein 2 isoform 2 [Homo sapiens]
          Length = 322

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 29/134 (21%)

Query: 255 NDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGV-------EPSIMGIGPIPAIKQAVTK 307
           +DGAAA +L  ++   K GL   A  +   ++         E SI+ +      K+A  K
Sbjct: 184 SDGAAAAILASEAFVQKYGLQSKAVEILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARK 243

Query: 308 ----AGWSLEDVDIFEINEAFAAVSAAIVKELGLNPE------------------KVNIE 345
               +G +  D+D+ E+++ F+       + LGL PE                   +N  
Sbjct: 244 CYEKSGLTPNDIDVIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWVINPS 303

Query: 346 GGAIALGHPLGASG 359
           GG I+ GHPLGA+G
Sbjct: 304 GGLISKGHPLGATG 317


>gi|154090979 hypothetical protein LOC57481 [Homo sapiens]
          Length = 1709

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 18/70 (25%), Positives = 30/70 (42%)

Query: 184  LSQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGT 243
            LS  +   A +   +++++ PV  S+ K     K    P+H S     SK +P   + G 
Sbjct: 1292 LSPRQLSQALRKPEYEQKVSPVSASSPKEWRNSKKQLPPKHSSQASDRSKFQPQMSSKGP 1351

Query: 244  GTVTPANASG 253
              V    +SG
Sbjct: 1352 VNVPVKQSSG 1361


>gi|56549696 E1A binding protein p400 [Homo sapiens]
          Length = 3122

 Score = 29.3 bits (64), Expect = 6.5
 Identities = 13/43 (30%), Positives = 25/43 (58%)

Query: 326  AVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLLH 368
            +V AA+V   G+    +N+ G ++A+G P  A+G  ++   +H
Sbjct: 2883 SVPAAVVSSPGVTTLPMNVAGISVAIGQPQKAAGQTVVAQPVH 2925


>gi|224926824 SH2B adaptor protein 1 isoform 2 [Homo sapiens]
          Length = 671

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 22/55 (40%), Positives = 25/55 (45%), Gaps = 5/55 (9%)

Query: 343 NIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE 397
           N  GGA  +G  L + G        H  ER+  SRG  AL  G GM     VQRE
Sbjct: 201 NSSGGAGTVGRGLVSDGTSPGERWTHRFERLRLSRGGGALKDGAGM-----VQRE 250


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 21/103 (20%)

Query: 199   DKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGA 258
             ++ +VP+L  T KGL E K  +F     N   +S  +P   T  T  V P +        
Sbjct: 14630 NEHLVPILTYTAKGLEEGKEYQFRVRAENAAGIS--EPSRATPPTKAVDPID-------- 14679

Query: 259   AAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAI 301
             A  V+++ S   KRG           ++ ++ SI G  P P I
Sbjct: 14680 APKVILRTSLEVKRG----------DEIALDASISG-SPYPTI 14711


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 21/103 (20%)

Query: 199  DKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGA 258
            ++ +VP+L  T KGL E K  +F     N   +S  +P   T  T  V P +        
Sbjct: 8325 NEHLVPILTYTAKGLEEGKEYQFRVRAENAAGIS--EPSRATPPTKAVDPID-------- 8374

Query: 259  AAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAI 301
            A  V+++ S   KRG           ++ ++ SI G  P P I
Sbjct: 8375 APKVILRTSLEVKRG----------DEIALDASISG-SPYPTI 8406


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 21/103 (20%)

Query: 199  DKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGA 258
            ++ +VP+L  T KGL E K  +F     N   +S  +P   T  T  V P +        
Sbjct: 8258 NEHLVPILTYTAKGLEEGKEYQFRVRAENAAGIS--EPSRATPPTKAVDPID-------- 8307

Query: 259  AAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAI 301
            A  V+++ S   KRG           ++ ++ SI G  P P I
Sbjct: 8308 APKVILRTSLEVKRG----------DEIALDASISG-SPYPTI 8339


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 21/103 (20%)

Query: 199  DKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGA 258
            ++ +VP+L  T KGL E K  +F     N   +S  +P   T  T  V P +        
Sbjct: 8133 NEHLVPILTYTAKGLEEGKEYQFRVRAENAAGIS--EPSRATPPTKAVDPID-------- 8182

Query: 259  AAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAI 301
            A  V+++ S   KRG           ++ ++ SI G  P P I
Sbjct: 8183 APKVILRTSLEVKRG----------DEIALDASISG-SPYPTI 8214


>gi|224926830 SH2B adaptor protein 1 isoform 3 [Homo sapiens]
          Length = 683

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 22/55 (40%), Positives = 25/55 (45%), Gaps = 5/55 (9%)

Query: 343 NIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE 397
           N  GGA  +G  L + G        H  ER+  SRG  AL  G GM     VQRE
Sbjct: 201 NSSGGAGTVGRGLVSDGTSPGERWTHRFERLRLSRGGGALKDGAGM-----VQRE 250


>gi|224926828 SH2B adaptor protein 1 isoform 2 [Homo sapiens]
          Length = 671

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 22/55 (40%), Positives = 25/55 (45%), Gaps = 5/55 (9%)

Query: 343 NIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE 397
           N  GGA  +G  L + G        H  ER+  SRG  AL  G GM     VQRE
Sbjct: 201 NSSGGAGTVGRGLVSDGTSPGERWTHRFERLRLSRGGGALKDGAGM-----VQRE 250


>gi|224926826 SH2B adaptor protein 1 isoform 1 [Homo sapiens]
          Length = 756

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 22/55 (40%), Positives = 25/55 (45%), Gaps = 5/55 (9%)

Query: 343 NIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE 397
           N  GGA  +G  L + G        H  ER+  SRG  AL  G GM     VQRE
Sbjct: 201 NSSGGAGTVGRGLVSDGTSPGERWTHRFERLRLSRGGGALKDGAGM-----VQRE 250


>gi|224926822 SH2B adaptor protein 1 isoform 2 [Homo sapiens]
          Length = 671

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 22/55 (40%), Positives = 25/55 (45%), Gaps = 5/55 (9%)

Query: 343 NIEGGAIALGHPLGASGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE 397
           N  GGA  +G  L + G        H  ER+  SRG  AL  G GM     VQRE
Sbjct: 201 NSSGGAGTVGRGLVSDGTSPGERWTHRFERLRLSRGGGALKDGAGM-----VQRE 250


>gi|149589021 doublecortin-like kinase 3 [Homo sapiens]
          Length = 648

 Score = 28.9 bits (63), Expect = 8.5
 Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 4/44 (9%)

Query: 186 QNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFP----RHG 225
           +++  +AQ A    K++V VL  T +GL EVK D  P    +HG
Sbjct: 230 EDQESHAQGAAKAKKDLVEVLPVTEEGLREVKKDTRPMSRSKHG 273


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,076,892
Number of Sequences: 37866
Number of extensions: 586902
Number of successful extensions: 1429
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1381
Number of HSP's gapped (non-prelim): 41
length of query: 397
length of database: 18,247,518
effective HSP length: 104
effective length of query: 293
effective length of database: 14,309,454
effective search space: 4192670022
effective search space used: 4192670022
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.