BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|145580602 translocation associated membrane protein 1-like 1 [Homo sapiens] (369 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|145580602 translocation associated membrane protein 1-like 1 ... 744 0.0 gi|7657655 translocation associated membrane protein 1 [Homo sap... 539 e-153 gi|6912450 translocation-associated membrane protein 2 [Homo sap... 319 2e-87 gi|205360977 LAG1 homolog, ceramide synthase 4 [Homo sapiens] 55 8e-08 gi|32455256 LAG1 longevity assurance 2 [Homo sapiens] 45 1e-04 gi|31077094 LAG1 longevity assurance 2 [Homo sapiens] 45 1e-04 gi|22218345 LAG1 homolog, ceramide synthase 5 [Homo sapiens] 38 0.017 gi|116235446 LAG1 longevity assurance homolog 3 [Homo sapiens] 36 0.063 gi|38176296 LAG1 homolog, ceramide synthase 1 isoform 2 [Homo sa... 31 1.6 gi|11641421 LAG1 homolog, ceramide synthase 1 isoform 1 [Homo sa... 31 1.6 gi|6005715 solute carrier family 6 (amino acid transporter), mem... 31 1.6 gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens] 31 2.0 gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein [... 30 3.5 gi|167004078 methyltransferase-like protein 1 isoform a [Homo sa... 29 7.7 gi|50593008 transmembrane BAX inhibitor motif containing 1 [Homo... 29 7.7 >gi|145580602 translocation associated membrane protein 1-like 1 [Homo sapiens] Length = 369 Score = 744 bits (1920), Expect = 0.0 Identities = 369/369 (100%), Positives = 369/369 (100%) Query: 1 MGLRKKSTKNPPVLSQEFILQNHADIVSCVGMFFLLGLVFEGTAEASIVFLTLQHSVAVP 60 MGLRKKSTKNPPVLSQEFILQNHADIVSCVGMFFLLGLVFEGTAEASIVFLTLQHSVAVP Sbjct: 1 MGLRKKSTKNPPVLSQEFILQNHADIVSCVGMFFLLGLVFEGTAEASIVFLTLQHSVAVP 60 Query: 61 AAEEQATGSKSLYYYGVKDLATVFFYMLVAIIIHATIQEYVLDKINKRMQFTKAKQNKFN 120 AAEEQATGSKSLYYYGVKDLATVFFYMLVAIIIHATIQEYVLDKINKRMQFTKAKQNKFN Sbjct: 61 AAEEQATGSKSLYYYGVKDLATVFFYMLVAIIIHATIQEYVLDKINKRMQFTKAKQNKFN 120 Query: 121 ESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQMKFFYISQLAYWFHAF 180 ESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQMKFFYISQLAYWFHAF Sbjct: 121 ESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQMKFFYISQLAYWFHAF 180 Query: 181 PELYFQKTKKQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLVLHYFVELLSHMCGLFY 240 PELYFQKTKKQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLVLHYFVELLSHMCGLFY Sbjct: 181 PELYFQKTKKQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLVLHYFVELLSHMCGLFY 240 Query: 241 FSDEKYQKGISLWAIVFILGRLVTLIVSVLTVGFHLAGSQNRNPDALTGNVNVLAAKIAV 300 FSDEKYQKGISLWAIVFILGRLVTLIVSVLTVGFHLAGSQNRNPDALTGNVNVLAAKIAV Sbjct: 241 FSDEKYQKGISLWAIVFILGRLVTLIVSVLTVGFHLAGSQNRNPDALTGNVNVLAAKIAV 300 Query: 301 LSSSCTIQAYVTWNLITLWLQRWVEDSNIQASCMKKKRSRSSKKRTENGVGVETSNRVDC 360 LSSSCTIQAYVTWNLITLWLQRWVEDSNIQASCMKKKRSRSSKKRTENGVGVETSNRVDC Sbjct: 301 LSSSCTIQAYVTWNLITLWLQRWVEDSNIQASCMKKKRSRSSKKRTENGVGVETSNRVDC 360 Query: 361 PPKRKEKSS 369 PPKRKEKSS Sbjct: 361 PPKRKEKSS 369 >gi|7657655 translocation associated membrane protein 1 [Homo sapiens] Length = 374 Score = 539 bits (1388), Expect = e-153 Identities = 267/374 (71%), Positives = 311/374 (83%), Gaps = 5/374 (1%) Query: 1 MGLRKKSTKNPPVLSQEFILQNHADIVSCVGMFFLLGLVFEGTAEASIVFLTLQHSVAVP 60 M +RKKSTK+PPVLS EF+LQNHADIVSCV M FLLGL+FE TA+ASI+F+TLQ++V +P Sbjct: 1 MAIRKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTLQYNVTLP 60 Query: 61 AAEEQATGSKSLYYYGVKDLATVFFYMLVAIIIHATIQEYVLDKINKRMQFTKAKQNKFN 120 A EEQAT S SLYYYG+KDLATVFFYMLVAIIIHA IQEY+LDKIN+RM F+K K +KFN Sbjct: 61 ATEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFN 120 Query: 121 ESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQMKFFYISQLAYWFHAF 180 ESGQ S FY F+C+WGTFILISEN +SDPT++W+A PH++MTFQMKFFYISQLAYW HAF Sbjct: 121 ESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAF 180 Query: 181 PELYFQKTKKQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLVLHYFVELLSHMCGLFY 240 PELYFQKTKK+DIPRQLVYIGL+LFHI GAYLL LNHLGL+LLVLHYFVE L H+ LFY Sbjct: 181 PELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFY 240 Query: 241 FSDEKYQKGISLWAIVFILGRLVTLIVSVLTVGFHLAGSQNRNPDALTGNVNVLAAKIAV 300 FS+EKYQKG SLWA++F+LGRL+TLI+SVLTVGF LA ++N+ D TGN NVLA +IAV Sbjct: 241 FSNEKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAV 300 Query: 301 LSSSCTIQAYVTWNLITLWLQRWVEDSNIQASCMKKK----RSRSSKKRTENGV-GVETS 355 L+S C QA++ W I L+RW E S QA +KKK + RSSKK TENGV G TS Sbjct: 301 LASICVTQAFMMWKFINFQLRRWREHSAFQAPAVKKKPTVTKGRSSKKGTENGVNGTLTS 360 Query: 356 NRVDCPPKRKEKSS 369 N D P +KEKSS Sbjct: 361 NVADSPRNKKEKSS 374 >gi|6912450 translocation-associated membrane protein 2 [Homo sapiens] Length = 370 Score = 319 bits (818), Expect = 2e-87 Identities = 155/328 (47%), Positives = 221/328 (67%), Gaps = 4/328 (1%) Query: 5 KKSTKNPPVLSQEFILQNHADIVSCVGMFFLLGLVFEGTAEASIVFLTLQHSVAVPAAEE 64 ++ TK+ P+ SQEF++ NHADI C+ + L+GL+FE TA+ + +F+ Q++++VP A+ Sbjct: 4 RRRTKSYPLFSQEFVIHNHADIGFCLVLCVLIGLMFEVTAKTAFLFILPQYNISVPTADS 63 Query: 65 QATGSKSLYYYGVKDLATVFFYMLVAIIIHATIQEYVLDKINKRMQFTKAKQNKFNESGQ 124 + Y+YG KDL T+ FY+ + II+HA +QEY+LDKI+KR+ +K K +KFNESGQ Sbjct: 64 ETVH----YHYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQ 119 Query: 125 FSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQMKFFYISQLAYWFHAFPELY 184 VF+F S IW +++++E L++P +W+ PH + FQ+KFFY+ QLAYW HA PELY Sbjct: 120 LVVFHFTSVIWCFYVVVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLAYWLHALPELY 179 Query: 185 FQKTKKQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLVLHYFVELLSHMCGLFYFSDE 244 FQK +K++IPRQL YI L+L HI GAYLL L+ LGL+LL+L Y E L H LFYF+DE Sbjct: 180 FQKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYFADE 239 Query: 245 KYQKGISLWAIVFILGRLVTLIVSVLTVGFHLAGSQNRNPDALTGNVNVLAAKIAVLSSS 304 +K S WA VF + RL L ++VL +GF LA +N+ D GN N L ++ VL Sbjct: 240 NNEKLFSAWAAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCVLLLV 299 Query: 305 CTIQAYVTWNLITLWLQRWVEDSNIQAS 332 C QA++ W I L+ W E N Q++ Sbjct: 300 CAAQAWLMWRFIHSQLRHWREYWNEQSA 327 >gi|205360977 LAG1 homolog, ceramide synthase 4 [Homo sapiens] Length = 394 Score = 55.5 bits (132), Expect = 8e-08 Identities = 46/181 (25%), Positives = 85/181 (46%), Gaps = 12/181 (6%) Query: 108 RMQFTKAKQNKFNESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQMKF 167 R Q TK KF E+ +FY S + G +L E+ L P + W P+ + + + Sbjct: 126 RPQLTK----KFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLYW 181 Query: 168 FYISQLAYWFHAFPELYFQKTKKQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLVLHY 227 +Y+ +L ++ L F K++D Q+++ + + +T +Y L +G L+L+LH Sbjct: 182 WYLLELGFYLSLLIRLPFD-VKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD 240 Query: 228 FVELLSHMCGLFYFSDEKYQKGIS----LWAIVFILGRLVTLIVSVLTVGFHLAGSQNRN 283 + L C + + +YQ+ +++ VF RLV +L ++ + S NR Sbjct: 241 SSDYLLEACKMVNYM--QYQQVCDALFLIFSFVFFYTRLVLFPTQILYTTYYESIS-NRG 297 Query: 284 P 284 P Sbjct: 298 P 298 >gi|32455256 LAG1 longevity assurance 2 [Homo sapiens] Length = 380 Score = 45.1 bits (105), Expect = 1e-04 Identities = 37/162 (22%), Positives = 70/162 (43%), Gaps = 5/162 (3%) Query: 107 KRMQFTKAKQNKFNESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQMK 166 +R Q + KF E+ FY + I G +++ + D +W+ P Sbjct: 121 RRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQY 180 Query: 167 FFYISQLA-YWFHAFPELYFQKTKKQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLVL 225 ++Y+ +L+ YW F K++D Q+++ + I+ ++ G L++ L Sbjct: 181 WYYMIELSFYWSLLFS--IASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMAL 238 Query: 226 HYFVELLSHMCGLFYFSDEK--YQKGISLWAIVFILGRLVTL 265 H + L +F ++ K ++AIVFI+ RLV L Sbjct: 239 HDSSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLVIL 280 >gi|31077094 LAG1 longevity assurance 2 [Homo sapiens] Length = 380 Score = 45.1 bits (105), Expect = 1e-04 Identities = 37/162 (22%), Positives = 70/162 (43%), Gaps = 5/162 (3%) Query: 107 KRMQFTKAKQNKFNESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQMK 166 +R Q + KF E+ FY + I G +++ + D +W+ P Sbjct: 121 RRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQY 180 Query: 167 FFYISQLA-YWFHAFPELYFQKTKKQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLVL 225 ++Y+ +L+ YW F K++D Q+++ + I+ ++ G L++ L Sbjct: 181 WYYMIELSFYWSLLFS--IASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMAL 238 Query: 226 HYFVELLSHMCGLFYFSDEK--YQKGISLWAIVFILGRLVTL 265 H + L +F ++ K ++AIVFI+ RLV L Sbjct: 239 HDSSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLVIL 280 >gi|22218345 LAG1 homolog, ceramide synthase 5 [Homo sapiens] Length = 392 Score = 37.7 bits (86), Expect = 0.017 Identities = 39/160 (24%), Positives = 67/160 (41%), Gaps = 5/160 (3%) Query: 106 NKRMQFTKAKQNKFNESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQM 165 ++R Q KF ES FY +G L S D W P ++ + Sbjct: 128 HRRNQDKPPTLTKFCESMWRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPFQPLSSGL 187 Query: 166 KFFYISQLA-YWFHAFPELYFQKTKKQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLV 224 +YI +LA YW F + F K++D V+ + + I+ +Y+ + +G L++ Sbjct: 188 YHYYIMELAFYWSLMFSQ--FTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVGTLIMC 245 Query: 225 LHYFVELLSHMCGLFYFSDEKYQKGISLWAIVFILGRLVT 264 LH + L L ++ KYQ+ ++F +VT Sbjct: 246 LHDVSDFLLEAAKLANYA--KYQRLCDTLFVIFSAVFMVT 283 >gi|116235446 LAG1 longevity assurance homolog 3 [Homo sapiens] Length = 383 Score = 35.8 bits (81), Expect = 0.063 Identities = 31/163 (19%), Positives = 66/163 (40%), Gaps = 9/163 (5%) Query: 106 NKRMQFTKAKQNKFNESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQM 165 ++R Q ++ KF E+ FY + G L + L D +W P + Sbjct: 119 SRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQ 178 Query: 166 KFFYISQLAYWFHAFPELYFQKTKKQ---DIPRQLVYIGLHLFHITGAYLLYLNHLGLLL 222 ++YI ++++++ L F +K I L I L F Y+ G L+ Sbjct: 179 YWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYI----RSGTLV 234 Query: 223 LVLHYFVELLSHMCGLFYFS--DEKYQKGISLWAIVFILGRLV 263 +++H ++ +F ++ + +++ +F + RL+ Sbjct: 235 MIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLI 277 >gi|38176296 LAG1 homolog, ceramide synthase 1 isoform 2 [Homo sapiens] Length = 337 Score = 31.2 bits (69), Expect = 1.6 Identities = 23/112 (20%), Positives = 50/112 (44%), Gaps = 3/112 (2%) Query: 118 KFNESGQFSVFYFFSCIWGTFILISENCL---SDPTLIWKARPHSMMTFQMKFFYISQLA 174 K ES +FY S + ++L + P++ + P + + Y+ Q + Sbjct: 98 KMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAAYLLQGS 157 Query: 175 YWFHAFPELYFQKTKKQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLVLH 226 ++ H+ + T ++D L++ + L I +Y +++G+L+L LH Sbjct: 158 FYGHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVLFLH 209 >gi|11641421 LAG1 homolog, ceramide synthase 1 isoform 1 [Homo sapiens] Length = 350 Score = 31.2 bits (69), Expect = 1.6 Identities = 23/112 (20%), Positives = 50/112 (44%), Gaps = 3/112 (2%) Query: 118 KFNESGQFSVFYFFSCIWGTFILISENCL---SDPTLIWKARPHSMMTFQMKFFYISQLA 174 K ES +FY S + ++L + P++ + P + + Y+ Q + Sbjct: 98 KMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAAYLLQGS 157 Query: 175 YWFHAFPELYFQKTKKQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLVLH 226 ++ H+ + T ++D L++ + L I +Y +++G+L+L LH Sbjct: 158 FYGHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVLFLH 209 >gi|6005715 solute carrier family 6 (amino acid transporter), member 14 [Homo sapiens] Length = 642 Score = 31.2 bits (69), Expect = 1.6 Identities = 21/96 (21%), Positives = 42/96 (43%), Gaps = 17/96 (17%) Query: 74 YYGVKDLATVFFY--------MLVAIIIHATIQ---EYVLDKINKRMQFTKAKQNKFNES 122 + G+K V ++ +L+ ++ AT++ + + I + FTK K+ + + Sbjct: 255 FKGIKSSGKVVYFTALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKD 314 Query: 123 GQFSVFYFFSCIWGTFILIS------ENCLSDPTLI 152 +FY S WG + +S NC SD ++ Sbjct: 315 AATQIFYSLSVAWGGLVALSSYNKFKNNCFSDAIVV 350 >gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens] Length = 279 Score = 30.8 bits (68), Expect = 2.0 Identities = 32/123 (26%), Positives = 53/123 (43%), Gaps = 17/123 (13%) Query: 252 LWAIVFILGRLVTLIVSVLTVGFHLAGSQ-------NRNP--DALTGNVNVLAAKIAVL- 301 LWA V LG + L + L + +HL G Q R P ++T N++ + K L Sbjct: 134 LWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFACRREPCLGSITCNLSRPSEKTIFLK 193 Query: 302 -----SSSCTIQAYVTWNLITL--WLQRWVEDSNIQASCMKKKRSRSSKKRTENGVGVET 354 S C + ++ L+ L W + W S+ + + +R KK T++ VET Sbjct: 194 TMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKYFLTSESTRRHKKATDSLPVVET 253 Query: 355 SNR 357 + Sbjct: 254 KEQ 256 >gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein [Homo sapiens] Length = 890 Score = 30.0 bits (66), Expect = 3.5 Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 2/59 (3%) Query: 261 RLVTLIVSVLTVGFHLAGSQNRNPDALTGNVNVLAAKIAVLSSSCTIQAYVTWNLITLW 319 RL+ V+ LTV + G + +PD+ T K+ + ++ Q VT ITLW Sbjct: 678 RLIQDAVTGLTVNGQITGDKRGSPDSKTR--KTYFGKLGIANAQMDFQVEVTTEKITLW 734 >gi|167004078 methyltransferase-like protein 1 isoform a [Homo sapiens] Length = 276 Score = 28.9 bits (63), Expect = 7.7 Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 17/77 (22%) Query: 167 FFYISQLAYWFHAFPELYFQKTKKQDIPRQLVYIGLHLFHITGAYLL----YLNHLGLLL 222 FFY QL F FP+ +F++TK H + I LL Y+ +G L+ Sbjct: 148 FFYKGQLTKMFFLFPDPHFKRTK-------------HKWRIISPTLLAEYAYVLRVGGLV 194 Query: 223 LVLHYFVELLSHMCGLF 239 + +EL MC F Sbjct: 195 YTITDVLELHDWMCTHF 211 >gi|50593008 transmembrane BAX inhibitor motif containing 1 [Homo sapiens] Length = 311 Score = 28.9 bits (63), Expect = 7.7 Identities = 13/38 (34%), Positives = 19/38 (50%) Query: 18 FILQNHADIVSCVGMFFLLGLVFEGTAEASIVFLTLQH 55 F Q D SC G+F +LG+V T + + L Q+ Sbjct: 208 FCFQTKVDFTSCTGLFCVLGIVLLVTGIVTSIVLYFQY 245 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.326 0.137 0.419 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,976,790 Number of Sequences: 37866 Number of extensions: 513401 Number of successful extensions: 1568 Number of sequences better than 10.0: 15 Number of HSP's better than 10.0 without gapping: 8 Number of HSP's successfully gapped in prelim test: 7 Number of HSP's that attempted gapping in prelim test: 1554 Number of HSP's gapped (non-prelim): 15 length of query: 369 length of database: 18,247,518 effective HSP length: 104 effective length of query: 265 effective length of database: 14,309,454 effective search space: 3792005310 effective search space used: 3792005310 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.