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Search of human proteins with 145207958
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|145207958 transmembrane protein 16G isoform NGEP long [Homo
sapiens]
(933 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|145207958 transmembrane protein 16G isoform NGEP long [Homo s... 1911 0.0
gi|218084958 anoctamin 4 [Homo sapiens] 571 e-162
gi|156766084 transmembrane protein 16C [Homo sapiens] 562 e-160
gi|209862785 anoctamin 2 [Homo sapiens] 548 e-156
gi|218081589 anoctamin 5 isoform b [Homo sapiens] 543 e-154
gi|47106048 anoctamin 5 isoform a [Homo sapiens] 543 e-154
gi|194306539 anoctamin 1, calcium activated chloride channel [Ho... 542 e-154
gi|218156303 anoctamin 6 isoform b [Homo sapiens] 521 e-148
gi|218156299 anoctamin 6 isoform a [Homo sapiens] 521 e-148
gi|218156307 anoctamin 6 isoform c [Homo sapiens] 491 e-138
gi|218156305 anoctamin 6 isoform c [Homo sapiens] 491 e-138
gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens] 379 e-105
gi|48717269 transmembrane protein 16G isoform NGEP short [Homo s... 318 1e-86
gi|94536803 transmembrane protein 16K [Homo sapiens] 194 3e-49
gi|239747244 PREDICTED: hypothetical protein [Homo sapiens] 178 2e-44
gi|169161033 PREDICTED: hypothetical protein [Homo sapiens] 172 1e-42
gi|55741655 anoctamin 8 [Homo sapiens] 121 3e-27
gi|239741065 PREDICTED: hypothetical protein [Homo sapiens] 110 5e-24
gi|25952092 potassium voltage-gated channel, shaker-related subf... 36 0.19
gi|22208951 ankyrin repeat and SOCS box-containing protein 3 iso... 33 1.6
gi|7705831 ankyrin repeat and SOCS box-containing protein 3 isof... 33 1.6
gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B... 32 2.1
gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B... 32 2.1
gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B... 32 2.8
gi|55743118 RAB3 GTPase-activating protein [Homo sapiens] 32 2.8
gi|224549005 RNA binding motif protein 17 [Homo sapiens] 32 3.6
gi|14249678 RNA binding motif protein 17 [Homo sapiens] 32 3.6
gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B... 32 3.6
gi|239752866 PREDICTED: similar to hCG1997308 [Homo sapiens] 32 3.6
gi|239747418 PREDICTED: hypothetical protein XP_002346694 [Homo ... 32 3.6
>gi|145207958 transmembrane protein 16G isoform NGEP long [Homo
sapiens]
Length = 933
Score = 1911 bits (4950), Expect = 0.0
Identities = 933/933 (100%), Positives = 933/933 (100%)
Query: 1 MRMAATAWAGLQGPPLPTLCPAVRTGLYCRDQAHAERWAMTSETSSGSHCARSRMLRRRA 60
MRMAATAWAGLQGPPLPTLCPAVRTGLYCRDQAHAERWAMTSETSSGSHCARSRMLRRRA
Sbjct: 1 MRMAATAWAGLQGPPLPTLCPAVRTGLYCRDQAHAERWAMTSETSSGSHCARSRMLRRRA 60
Query: 61 QEEDSTVLIDVSPPEAEKRGSYGSTAHASEPGGQQAAACRAGSPAKPRIADFVLVWEEDL 120
QEEDSTVLIDVSPPEAEKRGSYGSTAHASEPGGQQAAACRAGSPAKPRIADFVLVWEEDL
Sbjct: 61 QEEDSTVLIDVSPPEAEKRGSYGSTAHASEPGGQQAAACRAGSPAKPRIADFVLVWEEDL 120
Query: 121 KLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCVDQQDVQDGNTTVHYALLSASWAVLC 180
KLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCVDQQDVQDGNTTVHYALLSASWAVLC
Sbjct: 121 KLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCVDQQDVQDGNTTVHYALLSASWAVLC 180
Query: 181 YYAEDLRLKLPLQELPNQASNWSAGLLAWLGIPNVLLEVVPDVPPEYYSCRFRVNKLPRF 240
YYAEDLRLKLPLQELPNQASNWSAGLLAWLGIPNVLLEVVPDVPPEYYSCRFRVNKLPRF
Sbjct: 181 YYAEDLRLKLPLQELPNQASNWSAGLLAWLGIPNVLLEVVPDVPPEYYSCRFRVNKLPRF 240
Query: 241 LGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFKT 300
LGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFKT
Sbjct: 241 LGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFKT 300
Query: 301 PPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPA 360
PPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPA
Sbjct: 301 PPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPA 360
Query: 361 AVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLCLDCPFWLLSSACALAQAGRLFDH 420
AVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLCLDCPFWLLSSACALAQAGRLFDH
Sbjct: 361 AVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLCLDCPFWLLSSACALAQAGRLFDH 420
Query: 421 GGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAASAPMTAPNPI 480
GGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAASAPMTAPNPI
Sbjct: 421 GGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAASAPMTAPNPI 480
Query: 481 TGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAW 540
TGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAW
Sbjct: 481 TGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAW 540
Query: 541 ASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFIFQFVNFY 600
ASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFIFQFVNFY
Sbjct: 541 ASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFIFQFVNFY 600
Query: 601 SSPVYIAFFKGRFVGYPGNYHTLFGVRNEECAAGGCLIELAQELLVIMVGKQVINNMQEV 660
SSPVYIAFFKGRFVGYPGNYHTLFGVRNEECAAGGCLIELAQELLVIMVGKQVINNMQEV
Sbjct: 601 SSPVYIAFFKGRFVGYPGNYHTLFGVRNEECAAGGCLIELAQELLVIMVGKQVINNMQEV 660
Query: 661 LIPKLKGWWQKFRLRSKKRKAGASAGASQGPWEDDYELVPCEGLFDEYLEMVLQFGFVTI 720
LIPKLKGWWQKFRLRSKKRKAGASAGASQGPWEDDYELVPCEGLFDEYLEMVLQFGFVTI
Sbjct: 661 LIPKLKGWWQKFRLRSKKRKAGASAGASQGPWEDDYELVPCEGLFDEYLEMVLQFGFVTI 720
Query: 721 FVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISN 780
FVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISN
Sbjct: 721 FVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISN 780
Query: 781 AFLLAFSSDFLPRAYYRWTRAHDLRGFLNFTLARAPSSFAAAHNRTCRYRAFRDDDGHYS 840
AFLLAFSSDFLPRAYYRWTRAHDLRGFLNFTLARAPSSFAAAHNRTCRYRAFRDDDGHYS
Sbjct: 781 AFLLAFSSDFLPRAYYRWTRAHDLRGFLNFTLARAPSSFAAAHNRTCRYRAFRDDDGHYS 840
Query: 841 QTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKREYYLAKQALAENEVL 900
QTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKREYYLAKQALAENEVL
Sbjct: 841 QTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKREYYLAKQALAENEVL 900
Query: 901 FGTNGTKDEQPEGSELSSHWTPFTVPKASQLQQ 933
FGTNGTKDEQPEGSELSSHWTPFTVPKASQLQQ
Sbjct: 901 FGTNGTKDEQPEGSELSSHWTPFTVPKASQLQQ 933
>gi|218084958 anoctamin 4 [Homo sapiens]
Length = 920
Score = 571 bits (1471), Expect = e-162
Identities = 328/827 (39%), Positives = 478/827 (57%), Gaps = 54/827 (6%)
Query: 141 RETFLDNLRAAGLCVDQQDVQDGNTTVHYALLSASWAVLCYYAEDLRLKLPLQE----LP 196
RE F N+RA GL ++++ N+ + + L A W VL YAE + +++P + LP
Sbjct: 100 REVFERNIRAEGLQMEKESSLI-NSDIIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLP 158
Query: 197 NQASNWS------AGLLAWLGIPNVLL--EVVPDVPP-EYYSCRFRVNKLPRFLGSDNQD 247
+ S + WL + L E +PD+ + Y+ F ++ F+ N++
Sbjct: 159 RRYKFMSRIDKQISRFRRWLPKKPMRLDKETLPDLEENDCYTAPFSQQRIHHFI-IHNKE 217
Query: 248 TFFTSTKRHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFKTPPEGPQA 307
TFF + R +I+ IL + Y E KN +G+++LL G AAFPLH+G +++
Sbjct: 218 TFFNNATRSRIVHHILQRIKY-EEGKNKIGLNRLLTNGSYEAAFPLHEGSYRSKNSIRTH 276
Query: 308 PRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTLV 367
N R +L++ WA WG W KYQPLD VRRYFGEK+ LYFAWLG+YTG L PAA +G V
Sbjct: 277 GAENHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFV 336
Query: 368 FLVGCFLVFSDIPTQELCGSKDSFEMCPLCLD-CPFWLLSSACALAQAGRLFDHGGTVFF 426
FL G + ++E+C + D MCP+C CPF LS +C A+ LFD+G TVFF
Sbjct: 337 FLYGVTTLDHSQVSKEVCQATDII-MCPVCDKYCPFMRLSDSCVYAKVTHLFDNGATVFF 395
Query: 427 SLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAAS-APMTAPNPITGEDE 485
++FMA+WA + LE+WKR+ A +AY WD D+E+ EE RPQF A + NPI+G+ E
Sbjct: 396 AVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPE 455
Query: 486 PYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWASRIA 545
PY + R++ + I M+ VV+ + I++YR + + L+ +
Sbjct: 456 PYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVAT 515
Query: 546 SLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVY 605
+ T +N I++L+ +Y +A +LT E RT++++E++FTLK+F+FQFVN SS Y
Sbjct: 516 TGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFY 575
Query: 606 IAFFKGRFVGYPGNYHTLFGV-RNEECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPK 664
IAFF GRF G+PG Y L R EEC GCLI+L ++ +IMV KQ NN E+ P
Sbjct: 576 IAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPL 635
Query: 665 LKGWWQKFRLRSKKRKAGASAGASQGPWEDDYELVPCE--GLFDEYLEMVLQFGFVTIFV 722
++ WW + ++R + G S WE DY L P GLFDEYLEM+LQFGF TIFV
Sbjct: 636 IQNWWTRRKVRQEH---GPERKISFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFV 692
Query: 723 AACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAF 782
AA PLAPL ALLNN +EIRLDA KFV ++RRP+A RA+DIGIW+ IL G+ L+VI+NAF
Sbjct: 693 AAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAF 752
Query: 783 LLAFSSDFLPRAYYRW----------TRAHDLRGFLNFTLA--------------RAPSS 818
++A +SDF+PR Y + + G++N +L+ S
Sbjct: 753 VIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSE 812
Query: 819 FAAAHNRTCRYRAFRDDDGH-----YSQTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVP 873
F+ + CRYR +RD Y+ +W++LA RLAF+IVFEH+VF + L+ L+P
Sbjct: 813 FSGTPLKYCRYRDYRDPPHSLVPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIP 872
Query: 874 DIPESVEIKVKREYYLAKQALAENEVLFGTNGTKDEQPEGSELSSHW 920
D+P+ + +++RE YL ++ + E E+ K+ + G + W
Sbjct: 873 DLPKDLRDRMRREKYLIQEMMYEAELERLQKERKERKKNGKAHHNEW 919
>gi|156766084 transmembrane protein 16C [Homo sapiens]
Length = 981
Score = 562 bits (1449), Expect = e-160
Identities = 318/806 (39%), Positives = 477/806 (59%), Gaps = 54/806 (6%)
Query: 133 RTDMHRTWRETFLDNLRAAGLCVDQQDVQDGNTTVHYALLSASWAVLCYYAEDLRLKLPL 192
+T++ R TF NLRA GL ++++ + + + + W LC YAE L +++P
Sbjct: 172 KTNIQYDKRNTFEKNLRAEGLMLEKEPAI-ASPDIMFIKIHIPWDTLCKYAERLNIRMPF 230
Query: 193 QEL----------PNQASNWSAGLLAWLGIPNVLLE--VVPDVPP-EYYSCRFRVNKLPR 239
++ + + + W+ ++L+ PD+ + Y+ F ++
Sbjct: 231 RKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHH 290
Query: 240 FLGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFK 299
F+ +N+DTFF++ R +I++ +L +T Y + + GI +L+ G AAFP H+G +K
Sbjct: 291 FI-INNKDTFFSNATRSRIVYHMLERTKYENGISKV-GIRKLINNGSYIAAFPPHEGAYK 348
Query: 300 TPP----EGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTG 355
+ GPQ N R +L++ WARWG W K+QPLD +R YFGEK+ LYFAWLG+YTG
Sbjct: 349 SSQPIKTHGPQ----NNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTG 404
Query: 356 WLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLC-LDCPFWLLSSACALAQA 414
L+PAA+VG VF G F + + +QE+C + + F MCPLC +C L+ +C A+
Sbjct: 405 MLIPAAIVGLCVFFYGLFTMNNSQVSQEICKATEVF-MCPLCDKNCSLQRLNDSCIYAKV 463
Query: 415 GRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAASA-P 473
LFD+GGTVFF++FMA+WA + LE+WKR+ + L Y WD ++E+ EE RPQF A
Sbjct: 464 TYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAKYYK 523
Query: 474 MTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYR-AIMAIVVSRS 532
M NPITG+ EP+ P + R+L I M+++V+ + +++YR +M S
Sbjct: 524 MEIVNPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFK 583
Query: 533 GNTLLAAWASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVF 592
N + W S +N + I++L+ Y +A++LT E RT++++E++F LK+F
Sbjct: 584 WNFIKQYWQFA-TSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMF 642
Query: 593 IFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLFGV-RNEECAAGGCLIELAQELLVIMVGK 651
+FQFVN SS YIAFF GRFVG+PG Y+ LF R EEC GCLI+L ++ VIM K
Sbjct: 643 LFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLK 702
Query: 652 QVINNMQEVLIPKLKGWWQKFRLRSKKRKAGASAGASQGPWEDDYELVPCE--GLFDEYL 709
Q+ NN E+ P ++ WW + +++ AS WE+D+ L P GL DEYL
Sbjct: 703 QIWNNFMELGYPLIQNWWSRHKIKR------GIHDASIPQWENDWNLQPMNLHGLMDEYL 756
Query: 710 EMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHIL 769
EMVLQFGF TIFVAA PLAPL ALLNN +EIRLDA KFV ++RRP+ RA DIGIW IL
Sbjct: 757 EMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGIL 816
Query: 770 AGLTHLAVISNAFLLAFSSDFLPRAYYRW----------TRAHDLRGFLNFTLARAP-SS 818
G+ LAVI+NAF++A +SD++PR Y + + L+G++N +L+ S
Sbjct: 817 EGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSE 876
Query: 819 FAAAHNRTCRYRAFR-----DDDGHYSQTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVP 873
+ CRYR +R ++ YW++LA RLAF+IVFEH+VF + + L+P
Sbjct: 877 LGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIP 936
Query: 874 DIPESVEIKVKREYYLAKQALAENEV 899
D+P+ + +++RE YL ++ + E E+
Sbjct: 937 DVPKGLHDRIRREKYLVQEMMYEAEL 962
>gi|209862785 anoctamin 2 [Homo sapiens]
Length = 998
Score = 548 bits (1412), Expect = e-156
Identities = 314/793 (39%), Positives = 472/793 (59%), Gaps = 57/793 (7%)
Query: 141 RETFLDNLRAAGLCVDQQDVQDGNTTVHYALLSASWAVLCYYAEDLRLKLPLQELPNQAS 200
RE F NL AGL +++ D+++ + + + A W VL AE L++K+P +++ +
Sbjct: 155 REEFEHNLMEAGLELEK-DLENKSQGSIFVRIHAPWQVLAREAEFLKIKVPTKKMYEIKA 213
Query: 201 NWSAGLLAWLGIPNVLLEVVPDVPP------EYYSCRFRVNKLPRFLGSDNQDTFFTSTK 254
S + + + P VP + S F K+ + +DTFF +
Sbjct: 214 GGSIAKKFSAALQKLSSHLQPRVPEHSNNKMKNLSYPFSREKMYLY-NIQEKDTFFDNAT 272
Query: 255 RHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFKTPPEGPQAPRLNQRQ 314
R +I+ EIL +T N +GI+ L+A + AA+PLHDG + +P + +N R+
Sbjct: 273 RSRIVHEILKRTACSRAN-NTMGINSLIANNIYEAAYPLHDGEYDSPEDD-----MNDRK 326
Query: 315 VLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTLVFLVGCFL 374
+L+Q WAR+G + K+QP+D +R+YFGEK+ LYFAWLG YT +L+P++V+G +VFL GC
Sbjct: 327 LLYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVIVFLYGCAT 386
Query: 375 VFSDIPTQELCGSKDSFEMCPLC-LDCPFWLLSSACALAQAGRLFDHGGTVFFSLFMALW 433
+ DIP++E+C +++F MCPLC C +W LSSAC AQA LFD+ TVFFS+FMALW
Sbjct: 387 IEEDIPSREMCDQQNAFTMCPLCDKSCDYWNLSSACGTAQASHLFDNPATVFFSIFMALW 446
Query: 434 AVLLLEYWKRKSATLAYRWDCSDYEDTEERP----RPQFAA------------SAPMTAP 477
A + LE WKR L Y WD + E+ EER RP++ SA
Sbjct: 447 ATMFLENWKRLQMRLGYFWDLTGIEEEEERAQEHSRPEYETKVREKMLKESNQSAVQKLE 506
Query: 478 NPITG----EDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSG 533
T +DE + R L I+ M+A+ + +I+YR A +S +
Sbjct: 507 TNTTECGDEDDEDKLTWKDRFPGYLMNFASILFMIALTFSIVFGVIVYRITTAAALSLNK 566
Query: 534 NTLLAAWASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFI 593
T + A T ++NLV ILIL +IY ++A LT+ E+ +T+ FE+ LK F+
Sbjct: 567 ATRSNVRVTVTA--TAVIINLVVILILDEIYGAVAKWLTKIEVPKTEQTFEERLILKAFL 624
Query: 594 FQFVNFYSSPVYIAFFKGRFVGYPGNYHTLF-GVRNEECAAGGCLIELAQELLVIMVGKQ 652
+FVN YS Y+AFFKGRFVG PG+Y +F G R EECA GGCL+EL +L +IM+GKQ
Sbjct: 625 LKFVNAYSPIFYVAFFKGRFVGRPGSYVYVFDGYRMEECAPGGCLMELCIQLSIIMLGKQ 684
Query: 653 VI-NNMQEVLIPKLKGWWQKFRLRSKKRKAGASAGASQGPWEDDYELVPCEGLFDEYLEM 711
+I NN+ E+ +PKLK ++K + ++ + ++ W+ DY L P GL EY+EM
Sbjct: 685 LIQNNIFEIGVPKLKKLFRKLKDETEAGETDSAHSKHPEQWDLDYSLEPYTGLTPEYMEM 744
Query: 712 VLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAG 771
++QFGFVT+FVA+ PLAP+FALLNN +E+RLDA+KFV E RRP A R +DIGIWF IL+G
Sbjct: 745 IIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTELRRPDAVRTKDIGIWFDILSG 804
Query: 772 LTHLAVISNAFLLAFSSDFLPRAYYRWTRAHD--LRGFLNFTLA-----------RAPSS 818
+ +VISNAF++A +SDF+PR Y+++ +H+ L GF+N TL+ + +S
Sbjct: 805 IGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGTLHGFVNHTLSFFNVSQLKEGTQPENS 864
Query: 819 FAAAHNRTCRYRAFRD-----DDGHYSQTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVP 873
+ CR++ +R+ + +S+ YW +L+ RLAFVI+F+++V + L+D ++P
Sbjct: 865 QFDQEVQFCRFKDYREPPWAPNPYEFSKQYWFILSARLAFVIIFQNLVMFLSVLVDWMIP 924
Query: 874 DIPESVEIKVKRE 886
DIP + ++K+E
Sbjct: 925 DIPTDISDQIKKE 937
>gi|218081589 anoctamin 5 isoform b [Homo sapiens]
Length = 912
Score = 543 bits (1398), Expect = e-154
Identities = 326/830 (39%), Positives = 482/830 (58%), Gaps = 64/830 (7%)
Query: 108 RIADFVLVWEEDLKLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCV---DQQDVQDGN 164
R DFVL + +D+K D ++ R+ F NLR GL + D++D +DG
Sbjct: 77 RQIDFVLSYVDDVKKD----------AELKAERRKEFETNLRKTGLELEIEDKRDSEDGR 126
Query: 165 TTVHYALLSASWAVLCYYAEDLRLKLPLQE--LPNQASNWSAGLLAWLGIPNVLLEVVPD 222
T ++ + A W VL YAE L +K+P++E +P + +L + +P L P
Sbjct: 127 T--YFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLGPVRLP--LSVKYPH 182
Query: 223 VPPEYYSCRFRVNKLPRFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEK-KNLLGIHQL 281
PEY++ +F ++ FL D Q TFF S+ R++I++ IL++ P+G E K GI +L
Sbjct: 183 --PEYFTAQFSRHRQELFLIED-QATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERL 239
Query: 282 LAEGVLSAAFPLHDGPFKTPPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGE 341
L S+A+PLHDG + P E P N+R L Q+WAR+ + K QPLD ++ Y+GE
Sbjct: 240 LNSNTYSSAYPLHDGQYWKPSEPPNPT--NERYTLHQNWARFSYFYKEQPLDLIKNYYGE 297
Query: 342 KVALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEM--CPLCLD 399
K+ +YF +LGFYT L AAVVG F+ G + + + E+C + +M CPLC
Sbjct: 298 KIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQ 357
Query: 400 -CPFWLLSSACALAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYE 458
C +W L+S C ++ LFD+ TVFF++FM +W L LE+WK++ A L Y WD D+E
Sbjct: 358 VCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFE 417
Query: 459 DTEERP--RPQFAASAPMTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLV 516
+ +++ RP+F A N +T E EPY P +R + + +++VV +V
Sbjct: 418 EEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMV 477
Query: 517 SIILYR-AIMAIVVS-RSGNTLLAAWASRIA-----SLTGSVVNLVFILILSKIYVSLAH 569
++I+YR ++ A S + L S + SLTGS +N + ILIL+ Y ++
Sbjct: 478 AVIVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISA 537
Query: 570 VLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLFGV-RN 628
+T+ E+ RT ++E + TLK+F+FQFVNFYSS Y+AFFKG+FVGYPG Y LF R+
Sbjct: 538 WITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRS 597
Query: 629 EECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFRLRSKKRKAGASAGAS 688
EEC GGCLIEL +L +IM GKQ+ N++E + P WW ++RKA ++
Sbjct: 598 EECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWW-------RRRKARTNSEKL 650
Query: 689 QGPWEDDYELVPCE--GLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARK 746
WE D++L GLF EYLE V QFGFVT+FVA+ PLAPL AL+NN VEIR+DA K
Sbjct: 651 YSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWK 710
Query: 747 FVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRW----TRAH 802
+YRR VA +A IG+W IL G+ L+V +NAF++AF+SD +PR Y +
Sbjct: 711 LTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQ 770
Query: 803 DLRGFLN-----FTLARAPSSFAAAHNR---TCRYRAFR---DDDGHY--SQTYWNLLAI 849
+ G++N F +A P+ A + R TCRYR +R DD+ Y + +W++LA
Sbjct: 771 PMTGYVNNSLSVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVLAA 830
Query: 850 RLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKREYYLAKQALAENEV 899
++ F+IV EHVVF V LL ++PD+P+ V ++KRE + + L + E+
Sbjct: 831 KMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFEL 880
>gi|47106048 anoctamin 5 isoform a [Homo sapiens]
Length = 913
Score = 543 bits (1398), Expect = e-154
Identities = 326/830 (39%), Positives = 482/830 (58%), Gaps = 64/830 (7%)
Query: 108 RIADFVLVWEEDLKLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCV---DQQDVQDGN 164
R DFVL + +D+K D ++ R+ F NLR GL + D++D +DG
Sbjct: 78 RQIDFVLSYVDDVKKD----------AELKAERRKEFETNLRKTGLELEIEDKRDSEDGR 127
Query: 165 TTVHYALLSASWAVLCYYAEDLRLKLPLQE--LPNQASNWSAGLLAWLGIPNVLLEVVPD 222
T ++ + A W VL YAE L +K+P++E +P + +L + +P L P
Sbjct: 128 T--YFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLGPVRLP--LSVKYPH 183
Query: 223 VPPEYYSCRFRVNKLPRFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEK-KNLLGIHQL 281
PEY++ +F ++ FL D Q TFF S+ R++I++ IL++ P+G E K GI +L
Sbjct: 184 --PEYFTAQFSRHRQELFLIED-QATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERL 240
Query: 282 LAEGVLSAAFPLHDGPFKTPPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGE 341
L S+A+PLHDG + P E P N+R L Q+WAR+ + K QPLD ++ Y+GE
Sbjct: 241 LNSNTYSSAYPLHDGQYWKPSEPPNPT--NERYTLHQNWARFSYFYKEQPLDLIKNYYGE 298
Query: 342 KVALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEM--CPLCLD 399
K+ +YF +LGFYT L AAVVG F+ G + + + E+C + +M CPLC
Sbjct: 299 KIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQ 358
Query: 400 -CPFWLLSSACALAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYE 458
C +W L+S C ++ LFD+ TVFF++FM +W L LE+WK++ A L Y WD D+E
Sbjct: 359 VCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFE 418
Query: 459 DTEERP--RPQFAASAPMTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLV 516
+ +++ RP+F A N +T E EPY P +R + + +++VV +V
Sbjct: 419 EEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMV 478
Query: 517 SIILYR-AIMAIVVS-RSGNTLLAAWASRIA-----SLTGSVVNLVFILILSKIYVSLAH 569
++I+YR ++ A S + L S + SLTGS +N + ILIL+ Y ++
Sbjct: 479 AVIVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISA 538
Query: 570 VLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLFGV-RN 628
+T+ E+ RT ++E + TLK+F+FQFVNFYSS Y+AFFKG+FVGYPG Y LF R+
Sbjct: 539 WITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRS 598
Query: 629 EECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFRLRSKKRKAGASAGAS 688
EEC GGCLIEL +L +IM GKQ+ N++E + P WW ++RKA ++
Sbjct: 599 EECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWW-------RRRKARTNSEKL 651
Query: 689 QGPWEDDYELVPCE--GLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARK 746
WE D++L GLF EYLE V QFGFVT+FVA+ PLAPL AL+NN VEIR+DA K
Sbjct: 652 YSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWK 711
Query: 747 FVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRW----TRAH 802
+YRR VA +A IG+W IL G+ L+V +NAF++AF+SD +PR Y +
Sbjct: 712 LTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQ 771
Query: 803 DLRGFLN-----FTLARAPSSFAAAHNR---TCRYRAFR---DDDGHY--SQTYWNLLAI 849
+ G++N F +A P+ A + R TCRYR +R DD+ Y + +W++LA
Sbjct: 772 PMTGYVNNSLSVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVLAA 831
Query: 850 RLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKREYYLAKQALAENEV 899
++ F+IV EHVVF V LL ++PD+P+ V ++KRE + + L + E+
Sbjct: 832 KMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFEL 881
>gi|194306539 anoctamin 1, calcium activated chloride channel [Homo
sapiens]
Length = 986
Score = 542 bits (1396), Expect = e-154
Identities = 324/831 (38%), Positives = 480/831 (57%), Gaps = 81/831 (9%)
Query: 135 DMHRTWRETFLDNLRAAGLCVDQQDVQDGNTTVH---YALLSASWAVLCYYAEDLRLKLP 191
D R RE + NL AGL +++ D +T +H + + A W VLC AE L+LK+P
Sbjct: 122 DDKRFRREEYEGNLLEAGLELER----DEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMP 177
Query: 192 LQELPNQASNWSAGLLAWLGIPNVLLEVVPDVPPEYYSCRFRVNKLPRFLGS-------- 243
+++ + N + GLL I +VL ++ + P+ R + K + S
Sbjct: 178 TKKMYH--INETRGLLK--KINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFD 233
Query: 244 -DNQDTFFTSTKRHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFKTPP 302
++D+FF S R I++EIL +T K ++ GI LLA GV +AA+PLHDG +
Sbjct: 234 LSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSM-GITSLLANGVYAAAYPLHDGDYNG-- 290
Query: 303 EGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAV 362
+ N R++L++ WAR+G + KYQP+D VR+YFGEK+ LYFAWLG YT L+PA++
Sbjct: 291 ---ENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASI 347
Query: 363 VGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLC-LDCPFWLLSSACALAQAGRLFDHG 421
VG +VFL GC + +IP+ E+C + + MCPLC C +W +SSACA A+A LFD+
Sbjct: 348 VGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNP 407
Query: 422 GTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEE----RPRPQFAA------- 470
TVFFS+FMALWA +E+WKRK L YRWD + +E+ EE PR ++ A
Sbjct: 408 ATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSL 467
Query: 471 ----------------------SAPMTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMV 508
TA + D+ R R L V I+ M+
Sbjct: 468 KKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMI 527
Query: 509 AVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWASRIASLTGSVVNLVFILILSKIYVSLA 568
AV ++ +I+YR MA ++ + + + + + T ++NLV I++L ++Y +A
Sbjct: 528 AVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIA 587
Query: 569 HVLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLF-GVR 627
LT+ E+ +T+ FE+ K F+ +FVN Y+ Y+AFFKGRFVG PG+Y +F R
Sbjct: 588 RWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFR 647
Query: 628 NEECAAGGCLIELAQELLVIMVGKQVI-NNMQEVLIPKLKGWWQKFRLRSKKRKAGASAG 686
EECA GGCL+EL +L +IM+GKQ+I NN+ E+ IPK+K + +L+ +
Sbjct: 648 MEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECV 707
Query: 687 ASQGPWEDDYELVPCEGLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARK 746
+ +E DY L P GL EY+EM++QFGFVT+FVA+ PLAPLFALLNN +EIRLDA+K
Sbjct: 708 KRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKK 767
Query: 747 FVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRA--YYRWTRAHDL 804
FV E RRPVA RA+DIGIW++IL G+ LAVI NAF+++F+SDF+PR Y +++ +
Sbjct: 768 FVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTM 827
Query: 805 RGFLNFTLA----------RAPSS--FAAAHNRTCRYRAFRD---DDGHY--SQTYWNLL 847
GF+N TL+ AP+ + CRY+ +R+ + Y S+ +W +L
Sbjct: 828 HGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVL 887
Query: 848 AIRLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKREYYLAKQALAENE 898
A RLAFVIVF+++V + +D ++PDIP+ + ++ +E L + E
Sbjct: 888 AARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREE 938
>gi|218156303 anoctamin 6 isoform b [Homo sapiens]
Length = 892
Score = 521 bits (1343), Expect = e-148
Identities = 318/839 (37%), Positives = 477/839 (56%), Gaps = 69/839 (8%)
Query: 108 RIADFVLVWEEDLKLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCVDQ-QDVQDGNTT 166
R DFVLV+E++ + +++ + + R R+ + NL GL ++ + V D
Sbjct: 49 RRIDFVLVYEDESR----KETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLV 104
Query: 167 VHYALLSASWAVLCYYAEDLRLKLPLQELPNQASNWSA--GLLAWLGIPNVLLEVVPDVP 224
+ + A W VLC YAE + +KLPL+ PN N S+ G L W + E +
Sbjct: 105 --FVKVHAPWEVLCTYAEIMHIKLPLK--PNDLKNRSSAFGTLNWFTKVLSVDESIIKPE 160
Query: 225 PEYYSCRFRVNKLPRFLGSDNQDTFFTSTKRHQILFEILAKTPYGH-EKKNLLGIHQLLA 283
E+++ F N++ F D +D FF R +I++ IL++ Y + GI++L+
Sbjct: 161 QEFFTAPFEKNRMNDFYIVD-RDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVN 219
Query: 284 EGVLSAAFPLHDGPFKTPPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKV 343
G+ AAFPLHD F+ E P P N+R +L++ WA K QPLD +R+Y+GEK+
Sbjct: 220 SGIYKAAFPLHDCKFRRQSEDPSCP--NERYLLYREWAHPRSIYKKQPLDLIRKYYGEKI 277
Query: 344 ALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELC----GSKDSFEMCPLCLD 399
+YFAWLG+YT LL AAVVG FL G + ++E+C G K MCP C
Sbjct: 278 GIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGK--IIMCPQCDR 335
Query: 400 -CPFWLLSSACALAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYE 458
CPFW L+ C ++ +FD GT+ F++FM +W L LE+WKR+ A L Y WD + +
Sbjct: 336 LCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQ 395
Query: 459 DTEERPRPQFAASAPMTAPNPITGEDEPY-FPERSRARRMLAGSVVIVVMVAVVVMCLVS 517
EE+ RP++ A N IT E+E F + R+ + + + +++ ++
Sbjct: 396 Q-EEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIG 454
Query: 518 IILYRAIMAIVVSR------SGNTLLAAWAS--RIASLTGSVVNLVFILILSKIYVSLAH 569
II+YR + IV S +G + + + S+T S+++ + I+IL+ IY +A
Sbjct: 455 IIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAI 514
Query: 570 VLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGN-YHTLFGVRN 628
++T +E+ RTQT +E++ T+K+F+FQFVN+YSS YIAFFKG+FVGYPG+ + L RN
Sbjct: 515 MITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRN 574
Query: 629 EECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFRLRSKKRKAGASAGAS 688
EEC GGCL+EL +L +IM GK + NN+QEVL+P + +F S K
Sbjct: 575 EECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPR---- 630
Query: 689 QGPWEDDYELVPCE--GLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARK 746
WE DY L P GLF EYLEM++QFGFVT+FVA+ PLAPL AL+NN +EIR+DA K
Sbjct: 631 ---WEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWK 687
Query: 747 FVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRWT------- 799
++RR V E+AQDIG W I+ G+ LAV++NA ++AF+SD +PR Y W+
Sbjct: 688 LTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYG 747
Query: 800 --RAHDLRGFLNFTLA------------RAPSSFAAAHNRTCRYRAFRDDDGH-----YS 840
++ + G++N TL+ P S H TCRYR FR GH ++
Sbjct: 748 DHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHT-TCRYRDFRYPPGHPQEYKHN 806
Query: 841 QTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKREYYLAKQALAENEV 899
YW+++A +LAF+IV EHV++SV + +PD+ + + K++RE YL ++ L EN +
Sbjct: 807 IYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKLLHENHL 865
>gi|218156299 anoctamin 6 isoform a [Homo sapiens]
Length = 910
Score = 521 bits (1343), Expect = e-148
Identities = 318/839 (37%), Positives = 477/839 (56%), Gaps = 69/839 (8%)
Query: 108 RIADFVLVWEEDLKLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCVDQ-QDVQDGNTT 166
R DFVLV+E++ + +++ + + R R+ + NL GL ++ + V D
Sbjct: 67 RRIDFVLVYEDESR----KETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLV 122
Query: 167 VHYALLSASWAVLCYYAEDLRLKLPLQELPNQASNWSA--GLLAWLGIPNVLLEVVPDVP 224
+ + A W VLC YAE + +KLPL+ PN N S+ G L W + E +
Sbjct: 123 --FVKVHAPWEVLCTYAEIMHIKLPLK--PNDLKNRSSAFGTLNWFTKVLSVDESIIKPE 178
Query: 225 PEYYSCRFRVNKLPRFLGSDNQDTFFTSTKRHQILFEILAKTPYGH-EKKNLLGIHQLLA 283
E+++ F N++ F D +D FF R +I++ IL++ Y + GI++L+
Sbjct: 179 QEFFTAPFEKNRMNDFYIVD-RDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVN 237
Query: 284 EGVLSAAFPLHDGPFKTPPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKV 343
G+ AAFPLHD F+ E P P N+R +L++ WA K QPLD +R+Y+GEK+
Sbjct: 238 SGIYKAAFPLHDCKFRRQSEDPSCP--NERYLLYREWAHPRSIYKKQPLDLIRKYYGEKI 295
Query: 344 ALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELC----GSKDSFEMCPLCLD 399
+YFAWLG+YT LL AAVVG FL G + ++E+C G K MCP C
Sbjct: 296 GIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGK--IIMCPQCDR 353
Query: 400 -CPFWLLSSACALAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYE 458
CPFW L+ C ++ +FD GT+ F++FM +W L LE+WKR+ A L Y WD + +
Sbjct: 354 LCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQ 413
Query: 459 DTEERPRPQFAASAPMTAPNPITGEDEPY-FPERSRARRMLAGSVVIVVMVAVVVMCLVS 517
EE+ RP++ A N IT E+E F + R+ + + + +++ ++
Sbjct: 414 Q-EEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIG 472
Query: 518 IILYRAIMAIVVSR------SGNTLLAAWAS--RIASLTGSVVNLVFILILSKIYVSLAH 569
II+YR + IV S +G + + + S+T S+++ + I+IL+ IY +A
Sbjct: 473 IIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAI 532
Query: 570 VLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGN-YHTLFGVRN 628
++T +E+ RTQT +E++ T+K+F+FQFVN+YSS YIAFFKG+FVGYPG+ + L RN
Sbjct: 533 MITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRN 592
Query: 629 EECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFRLRSKKRKAGASAGAS 688
EEC GGCL+EL +L +IM GK + NN+QEVL+P + +F S K
Sbjct: 593 EECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPR---- 648
Query: 689 QGPWEDDYELVPCE--GLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARK 746
WE DY L P GLF EYLEM++QFGFVT+FVA+ PLAPL AL+NN +EIR+DA K
Sbjct: 649 ---WEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWK 705
Query: 747 FVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRWT------- 799
++RR V E+AQDIG W I+ G+ LAV++NA ++AF+SD +PR Y W+
Sbjct: 706 LTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYG 765
Query: 800 --RAHDLRGFLNFTLA------------RAPSSFAAAHNRTCRYRAFRDDDGH-----YS 840
++ + G++N TL+ P S H TCRYR FR GH ++
Sbjct: 766 DHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHT-TCRYRDFRYPPGHPQEYKHN 824
Query: 841 QTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKREYYLAKQALAENEV 899
YW+++A +LAF+IV EHV++SV + +PD+ + + K++RE YL ++ L EN +
Sbjct: 825 IYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQREKYLTQKLLHENHL 883
>gi|218156307 anoctamin 6 isoform c [Homo sapiens]
Length = 929
Score = 491 bits (1265), Expect = e-138
Identities = 304/800 (38%), Positives = 453/800 (56%), Gaps = 69/800 (8%)
Query: 108 RIADFVLVWEEDLKLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCVDQ-QDVQDGNTT 166
R DFVLV+E++ + +++ + + R R+ + NL GL ++ + V D
Sbjct: 67 RRIDFVLVYEDESR----KETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLV 122
Query: 167 VHYALLSASWAVLCYYAEDLRLKLPLQELPNQASNWSA--GLLAWLGIPNVLLEVVPDVP 224
+ + A W VLC YAE + +KLPL+ PN N S+ G L W + E +
Sbjct: 123 --FVKVHAPWEVLCTYAEIMHIKLPLK--PNDLKNRSSAFGTLNWFTKVLSVDESIIKPE 178
Query: 225 PEYYSCRFRVNKLPRFLGSDNQDTFFTSTKRHQILFEILAKTPYGH-EKKNLLGIHQLLA 283
E+++ F N++ F D +D FF R +I++ IL++ Y + GI++L+
Sbjct: 179 QEFFTAPFEKNRMNDFYIVD-RDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVN 237
Query: 284 EGVLSAAFPLHDGPFKTPPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKV 343
G+ AAFPLHD F+ E P P N+R +L++ WA K QPLD +R+Y+GEK+
Sbjct: 238 SGIYKAAFPLHDCKFRRQSEDPSCP--NERYLLYREWAHPRSIYKKQPLDLIRKYYGEKI 295
Query: 344 ALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELC----GSKDSFEMCPLCLD 399
+YFAWLG+YT LL AAVVG FL G + ++E+C G K MCP C
Sbjct: 296 GIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGK--IIMCPQCDR 353
Query: 400 -CPFWLLSSACALAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYE 458
CPFW L+ C ++ +FD GT+ F++FM +W L LE+WKR+ A L Y WD + +
Sbjct: 354 LCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQ 413
Query: 459 DTEERPRPQFAASAPMTAPNPITGEDEPY-FPERSRARRMLAGSVVIVVMVAVVVMCLVS 517
EE+ RP++ A N IT E+E F + R+ + + + +++ ++
Sbjct: 414 Q-EEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIG 472
Query: 518 IILYRAIMAIVVSR------SGNTLLAAWAS--RIASLTGSVVNLVFILILSKIYVSLAH 569
II+YR + IV S +G + + + S+T S+++ + I+IL+ IY +A
Sbjct: 473 IIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAI 532
Query: 570 VLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGN-YHTLFGVRN 628
++T +E+ RTQT +E++ T+K+F+FQFVN+YSS YIAFFKG+FVGYPG+ + L RN
Sbjct: 533 MITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRN 592
Query: 629 EECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFRLRSKKRKAGASAGAS 688
EEC GGCL+EL +L +IM GK + NN+QEVL+P + +F S K
Sbjct: 593 EECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPR---- 648
Query: 689 QGPWEDDYELVPCE--GLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARK 746
WE DY L P GLF EYLEM++QFGFVT+FVA+ PLAPL AL+NN +EIR+DA K
Sbjct: 649 ---WEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWK 705
Query: 747 FVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRWT------- 799
++RR V E+AQDIG W I+ G+ LAV++NA ++AF+SD +PR Y W+
Sbjct: 706 LTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYG 765
Query: 800 --RAHDLRGFLNFTLA------------RAPSSFAAAHNRTCRYRAFRDDDGH-----YS 840
++ + G++N TL+ P S H TCRYR FR GH ++
Sbjct: 766 DHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHT-TCRYRDFRYPPGHPQEYKHN 824
Query: 841 QTYWNLLAIRLAFVIVFEHV 860
YW+++A +LAF+IV E++
Sbjct: 825 IYYWHVIAAKLAFIIVMEYL 844
>gi|218156305 anoctamin 6 isoform c [Homo sapiens]
Length = 929
Score = 491 bits (1265), Expect = e-138
Identities = 304/800 (38%), Positives = 453/800 (56%), Gaps = 69/800 (8%)
Query: 108 RIADFVLVWEEDLKLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCVDQ-QDVQDGNTT 166
R DFVLV+E++ + +++ + + R R+ + NL GL ++ + V D
Sbjct: 67 RRIDFVLVYEDESR----KETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLV 122
Query: 167 VHYALLSASWAVLCYYAEDLRLKLPLQELPNQASNWSA--GLLAWLGIPNVLLEVVPDVP 224
+ + A W VLC YAE + +KLPL+ PN N S+ G L W + E +
Sbjct: 123 --FVKVHAPWEVLCTYAEIMHIKLPLK--PNDLKNRSSAFGTLNWFTKVLSVDESIIKPE 178
Query: 225 PEYYSCRFRVNKLPRFLGSDNQDTFFTSTKRHQILFEILAKTPYGH-EKKNLLGIHQLLA 283
E+++ F N++ F D +D FF R +I++ IL++ Y + GI++L+
Sbjct: 179 QEFFTAPFEKNRMNDFYIVD-RDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVN 237
Query: 284 EGVLSAAFPLHDGPFKTPPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKV 343
G+ AAFPLHD F+ E P P N+R +L++ WA K QPLD +R+Y+GEK+
Sbjct: 238 SGIYKAAFPLHDCKFRRQSEDPSCP--NERYLLYREWAHPRSIYKKQPLDLIRKYYGEKI 295
Query: 344 ALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELC----GSKDSFEMCPLCLD 399
+YFAWLG+YT LL AAVVG FL G + ++E+C G K MCP C
Sbjct: 296 GIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGK--IIMCPQCDR 353
Query: 400 -CPFWLLSSACALAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYE 458
CPFW L+ C ++ +FD GT+ F++FM +W L LE+WKR+ A L Y WD + +
Sbjct: 354 LCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQ 413
Query: 459 DTEERPRPQFAASAPMTAPNPITGEDEPY-FPERSRARRMLAGSVVIVVMVAVVVMCLVS 517
EE+ RP++ A N IT E+E F + R+ + + + +++ ++
Sbjct: 414 Q-EEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIG 472
Query: 518 IILYRAIMAIVVSR------SGNTLLAAWAS--RIASLTGSVVNLVFILILSKIYVSLAH 569
II+YR + IV S +G + + + S+T S+++ + I+IL+ IY +A
Sbjct: 473 IIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAI 532
Query: 570 VLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGN-YHTLFGVRN 628
++T +E+ RTQT +E++ T+K+F+FQFVN+YSS YIAFFKG+FVGYPG+ + L RN
Sbjct: 533 MITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRN 592
Query: 629 EECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFRLRSKKRKAGASAGAS 688
EEC GGCL+EL +L +IM GK + NN+QEVL+P + +F S K
Sbjct: 593 EECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPR---- 648
Query: 689 QGPWEDDYELVPCE--GLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARK 746
WE DY L P GLF EYLEM++QFGFVT+FVA+ PLAPL AL+NN +EIR+DA K
Sbjct: 649 ---WEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWK 705
Query: 747 FVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRWT------- 799
++RR V E+AQDIG W I+ G+ LAV++NA ++AF+SD +PR Y W+
Sbjct: 706 LTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYG 765
Query: 800 --RAHDLRGFLNFTLA------------RAPSSFAAAHNRTCRYRAFRDDDGH-----YS 840
++ + G++N TL+ P S H TCRYR FR GH ++
Sbjct: 766 DHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHT-TCRYRDFRYPPGHPQEYKHN 824
Query: 841 QTYWNLLAIRLAFVIVFEHV 860
YW+++A +LAF+IV E++
Sbjct: 825 IYYWHVIAAKLAFIIVMEYL 844
>gi|145611446 tumor protein p53 inducible protein 5 [Homo sapiens]
Length = 782
Score = 379 bits (973), Expect = e-105
Identities = 245/673 (36%), Positives = 364/673 (54%), Gaps = 67/673 (9%)
Query: 281 LLAEGVLSAAFPLHDGPFKTPPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFG 340
L+ +GV A FPLH G + L + WARW + QP+D +R YFG
Sbjct: 141 LMKDGVFEARFPLHKGEGR----------------LKKTWARWRHMFREQPVDEIRNYFG 184
Query: 341 EKVALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLCLDC 400
EKVALYF WLG+YT L+PAA+ G LVFL G L + ++E+C + D MCPL
Sbjct: 185 EKVALYFVWLGWYTYMLVPAALTGLLVFLSGFSLFEASQISKEICEAHDIL-MCPLGDHS 243
Query: 401 P-FWLLSSACALAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYED 459
+ LS C A+ LFD+ GTV F++FMALWA + LE WKR+ A + WD +++
Sbjct: 244 RRYQRLSETCTFAKLTHLFDNDGTVVFAIFMALWATVFLEIWKRQRARVVLHWDLYVWDE 303
Query: 460 TEERPRPQFAASAPMTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSII 519
+E Q I D P + R V+ ++M+ +++ ++
Sbjct: 304 EQEEMALQL-----------INCPDYKLRPYQHSYLRSTVILVLTLLMICLMIGMAHVLV 352
Query: 520 LYRAIMAIVVSRSGNTLLAAWASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRT 579
+YR + + + S S L + +TG++V+ V I+I++KI +A L +EM RT
Sbjct: 353 VYRVLASALFSSSAVPFLEEQVTTAVVVTGALVHYVTIIIMTKINRCVALKLCDFEMPRT 412
Query: 580 QTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLFGV-RNEECAAGGCLI 638
++ E FT++ F QF +SS +YIAF GR G+PG L G+ + EEC A GC++
Sbjct: 413 FSERESRFTIRFFTLQFFTHFSSLIYIAFILGRINGHPGKSTRLAGLWKLEECHASGCMM 472
Query: 639 ELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFRLRSKKRKAGASAGASQGP----WED 694
+L ++ +IM KQ ++N E L+P W + RS + A S + P W
Sbjct: 473 DLFVQMAIIMGLKQTLSNCVEYLVP-----WVTHKCRSLR--ASESGHLPRDPELRDWRR 525
Query: 695 DYELVPCE--GLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYR 752
+Y L P LFDE++EM++Q+GF TIFVAA PLAPL AL +N VEIRLDA K V R
Sbjct: 526 NYLLNPVNTFSLFDEFMEMMIQYGFTTIFVAAFPLAPLLALFSNLVEIRLDAIKMVWLQR 585
Query: 753 RPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRW----------TRAH 802
R V +A+DIG W +L + LAVI+N ++AF+S+F+PR Y++ +
Sbjct: 586 RLVPRKAKDIGTWLQVLETIGVLAVIANGMVIAFTSEFIPRVVYKYRYSPCLKEGNSTVD 645
Query: 803 DLRGFLNFTLA-------RAPSSFAAAHNRT-CRYRAFRD-DDGHYSQTYWNLLAIRLAF 853
L+G++N +L+ + P + N T CRYR +R+ D ++S+ +W LLAIRLAF
Sbjct: 646 CLKGYVNHSLSVFHTKDFQDPDGIEGSENVTLCRYRDYRNPPDYNFSEQFWFLLAIRLAF 705
Query: 854 VIVFEHVVFSVGRLLDLLVPDIPESVEIKV-KREYYLAKQALAENEVLFGTNGTKDEQPE 912
VI+FEHV + + VPDIP+SV+ KV + +Y ++ + G G P
Sbjct: 706 VILFEHVALCIKLIAAWFVPDIPQSVKNKVLEVKYQRLREKMWHGRQRLGGVGAGSRPP- 764
Query: 913 GSELSSHWTPFTV 925
+ +H TP ++
Sbjct: 765 ---MPAHPTPASI 774
>gi|48717269 transmembrane protein 16G isoform NGEP short [Homo
sapiens]
Length = 179
Score = 318 bits (816), Expect = 1e-86
Identities = 156/157 (99%), Positives = 156/157 (99%), Gaps = 1/157 (0%)
Query: 1 MRMAATAWAGLQGPPLPTLCPAVRTGLYCRDQAHAERWAMTSETSSGSHCARSRMLRRRA 60
MRMAATAWAGLQGPPLPTLCPAVRTGLYCRDQAHAERWAMTSETSSGSHCARSRMLRRRA
Sbjct: 1 MRMAATAWAGLQGPPLPTLCPAVRTGLYCRDQAHAERWAMTSETSSGSHCARSRMLRRRA 60
Query: 61 QEEDSTVLIDVSPPEAEKRGSYGSTAHASEPGGQQAAACRAGSPAKPRIADFVLVWEEDL 120
QEEDSTVLIDVSPPEAEKRGSYGSTAHASEPGGQQAAACRAGSPAKPRI DFVLVWEEDL
Sbjct: 61 QEEDSTVLIDVSPPEAEKRGSYGSTAHASEPGGQQAAACRAGSPAKPRI-DFVLVWEEDL 119
Query: 121 KLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCVDQ 157
KLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCVDQ
Sbjct: 120 KLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCVDQ 156
>gi|94536803 transmembrane protein 16K [Homo sapiens]
Length = 660
Score = 194 bits (493), Expect = 3e-49
Identities = 167/689 (24%), Positives = 285/689 (41%), Gaps = 162/689 (23%)
Query: 244 DNQDTFFTSTKRHQILFEILAKTPYGHEK-------------KNLLGIHQLLAEGVLSAA 290
DN D F T + I+ L EK K+LL +LL G++
Sbjct: 113 DNNDDFLTMAECQFIIKHELENLRAKDEKMIPGYPQAKLYPGKSLL--RRLLTSGIVIQV 170
Query: 291 FPLHDGPFKTPPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWL 350
FPLHD E R KYQP+D +R YFGE +ALYF +L
Sbjct: 171 FPLHDSEALKKLEDTWYTRFAL---------------KYQPIDSIRGYFGETIALYFGFL 215
Query: 351 GFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLCLDCPFWLLSSACA 410
++T L+P AV+G P++L
Sbjct: 216 EYFTFALIPMAVIGL-----------------------------------PYYLFVWE-- 238
Query: 411 LAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAA 470
D+ V F+ F +W+ ++LE WKR A + YRW + E PRP F
Sbjct: 239 --------DYDKYVIFASFNLIWSTVILELWKRGCANMTYRWGTLLMKRKFEEPRPGFHG 290
Query: 471 SAPMTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVS 530
+ N ITG++EP +P R R+ S+ V + + ++ I + A+ +
Sbjct: 291 ---VLGINSITGKEEPLYPSYKRQLRIYLVSLPFVCLCLYFSLYVMMIYFDMEVWALGLH 347
Query: 531 RSGNTLLAAWASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLK 590
+ + W S + S++ + I I++++Y A LT WE HR ++ +++ LK
Sbjct: 348 ENSGS---EWTS-VLLYVPSIIYAIVIEIMNRLYRYAAEFLTSWENHRLESAYQNHLILK 403
Query: 591 VFIFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLFGVRNEECAAGGCLIELAQELLVIMVG 650
V +F F+N ++S YIAF +++ + L Q L +++
Sbjct: 404 VLVFNFLNCFASLFYIAFV----------------LKDMKL--------LRQSLATLLIT 439
Query: 651 KQVINNMQEVLIPKLKGWWQ-KFRLRSKKRKAGASAGASQGPWED---DYELVPCEGLFD 706
Q++N + E +P W Q K +R K++ A +E + E+ G FD
Sbjct: 440 SQILNQIMESFLPY---WLQRKHGVRVKRKVQALKADIDATLYEQVILEKEMGTYLGTFD 496
Query: 707 EYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWF 766
+YLE+ LQFG+V++F PLA FA+LNN+ E+ DA K ++RP +E + +IG+W
Sbjct: 497 DYLELFLQFGYVSLFSCVYPLAAAFAVLNNFTEVNSDALKMCRVFKRPFSEPSANIGVWQ 556
Query: 767 HILAGLTHLAVISNAFLLAFSSDFLPRAYYRWTRAHDLRGFLNFTLARAPSSFAAAHNRT 826
++ ++V++N L+ S
Sbjct: 557 LAFETMSVISVVTNCALIGMSPQV------------------------------------ 580
Query: 827 CRYRAFRDDDGHYSQTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKRE 886
+ + ++ +L+ I +A EH + ++ +L +PD P +++K+ R
Sbjct: 581 ---------NAVFPESKADLILIVVA----VEHALLALKFILAFAIPDKPRHIQMKLARL 627
Query: 887 YYLAKQALAENEVLFGTNGTKDEQPEGSE 915
+ + +AL + ++ T K+E E +
Sbjct: 628 EFESLEALKQQQMKLVTENLKEEPMESGK 656
>gi|239747244 PREDICTED: hypothetical protein [Homo sapiens]
Length = 719
Score = 178 bits (451), Expect = 2e-44
Identities = 155/508 (30%), Positives = 209/508 (41%), Gaps = 152/508 (29%)
Query: 417 LFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTE--------------- 461
LFDH GTVFFS+FM+ W L + SATLA+ WDCSD++D E
Sbjct: 258 LFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWDCSDF 317
Query: 462 -----------------------ERPRPQFAASAPMTAPNPITGEDEPYFPERSRARRML 498
E P QFAA A NP+TG EPYF S +L
Sbjct: 318 QDQEVMPSSALHHWDCSDFQDQEECPHLQFAALALQMTQNPVTGLKEPYFQPHSCLSHLL 377
Query: 499 AGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWASRIASLTGSVVNLVFIL 558
S I+ ++ VV++ LVS+I+Y I++I + +GN+
Sbjct: 378 TSSAAILTVLCVVMIFLVSVIIYHGIISIAMFHTGNS----------------------- 414
Query: 559 ILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPG 618
+ ++ A+VL W + + + V F F
Sbjct: 415 ----VLMTQANVL--WGNGGDASMKMPSLSFSVCQFLF---------------------- 446
Query: 619 NYHTLFGVRNEECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFRLRSKK 678
+ L G+ +C GGC I++ Q+L++IMVGKQ++N+M+E +
Sbjct: 447 -FSLLHGILQRQCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFV----------------- 488
Query: 679 RKAGASAGASQGPWEDDYELVPCEGLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWV 738
G GP D PC LQFGF+TIFV A LAPLF LLNN V
Sbjct: 489 -------GLGGGPGPD----TPCLP--------ELQFGFITIFVGAFLLAPLFTLLNNRV 529
Query: 739 EIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRW 798
EI LDA KF+C+Y+RP+A R G S+ LPR R
Sbjct: 530 EIGLDAHKFLCKYQRPMAGRGWTSG---------------SDCSCWRPCELILPRTNARS 574
Query: 799 TRAHDLRGFLNFTLARAPSSFAA--------AHNRTCRYRAFRDDDGHYSQTYWNLLA-- 848
+ L G L R A RY+A RD + + YW LLA
Sbjct: 575 RLGYWLNG-QGQILGRRRGGNAGFGVEIREPLQTPQPRYKASRDVGVNLALFYWKLLAVH 633
Query: 849 IRLAFVIVFEHVVFSVGRLLDLLVPDIP 876
+ L F+I FE+VVF D LVPD+P
Sbjct: 634 VHLGFIIAFENVVFFFLCPNDRLVPDVP 661
Score = 102 bits (253), Expect = 2e-21
Identities = 90/321 (28%), Positives = 133/321 (41%), Gaps = 75/321 (23%)
Query: 261 EILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFKTPPEGPQAPRLNQRQVLFQHW 320
EIL +T +K +GI LL G F+ P LN Q+L+ +W
Sbjct: 190 EILDRTISRKKKHTEMGIAHLL-------------GLFELPGYQVPGSDLNSCQLLYPYW 236
Query: 321 ARWGKWNKYQPLDH----VRRYFGEKVALYFAWLGFYTGWLLPAAV---VGTLVFLVGCF 373
A WG W+KYQPLD + F ++F+ + G LP A+ TL C
Sbjct: 237 ACWGYWHKYQPLDQPLDKLSCLFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDC- 295
Query: 374 LVFSDIPTQELCGSKDSFEMCPLCLDCPFWLLSSACALAQAGRLFDHGGTVFFSLFMALW 433
SD QE S P DC +
Sbjct: 296 ---SDFQDQEAMPSS-----APHHWDCSDF------------------------------ 317
Query: 434 AVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAASAPMTAPNPITGEDEPYFPERSR 493
+ + ++ + WDCSD++D EE P QFAA A NP+TG EPYF S
Sbjct: 318 -----QDQEVMPSSALHHWDCSDFQDQEECPHLQFAALALQMTQNPVTGLKEPYFQPHSC 372
Query: 494 ARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWAS----------- 542
+L S I+ ++ VV++ LVS+I+Y I++I + +GN++L A+
Sbjct: 373 LSHLLTSSAAILTVLCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQANVLWGNGGDASM 432
Query: 543 RIASLTGSVVNLVFILILSKI 563
++ SL+ SV +F +L I
Sbjct: 433 KMPSLSFSVCQFLFFSLLHGI 453
>gi|169161033 PREDICTED: hypothetical protein [Homo sapiens]
Length = 723
Score = 172 bits (436), Expect = 1e-42
Identities = 165/573 (28%), Positives = 225/573 (39%), Gaps = 181/573 (31%)
Query: 352 FYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLCLDCPFWLLSSACAL 411
FY LLP +VGTL+F+ V ++ W+
Sbjct: 226 FYMACLLPVTLVGTLLFISSLVTVGTNTLV---------------------WVAVEG--- 261
Query: 412 AQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTE---------- 461
L D GTVFFS+FM+ W L + SATLA+ WDCSD++D E
Sbjct: 262 -----LGDGLGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHW 316
Query: 462 ----------------------------ERPRPQFAASAPMTAPNPITGEDEPYFPERSR 493
E P QFAA A NP+TG EPYF S
Sbjct: 317 DCSDFQDQEVMPSSALHHWDCSDFQDQEECPHLQFAALALQMTQNPVTGLKEPYFQPHSC 376
Query: 494 ARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWASRIASLTGSVVN 553
+L S I+ ++ VV++ LVS+I+Y I++I + +GN+
Sbjct: 377 LSHLLTSSAAILTVLCVVMIFLVSVIIYHGIISIAMFHTGNS------------------ 418
Query: 554 LVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRF 613
+ ++ A+VL W + + + V F F
Sbjct: 419 ---------VLMTQANVL--WGNGGDASMKMPSLSFSVCQFLF----------------- 450
Query: 614 VGYPGNYHTLFGVRNEECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFR 673
+ L G+ +C GGC I++ Q+L++IMVGKQ++N+M+E +
Sbjct: 451 ------FSLLHGILQRQCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFV------------ 492
Query: 674 LRSKKRKAGASAGASQGPWEDDYELVPCEGLFDEYLEMVLQFGFVTIFVAACPLAPLFAL 733
G GP D PC LQFGF+TIFV A LAPLF L
Sbjct: 493 ------------GLGGGPGPD----TPCLP--------ELQFGFITIFVGAFLLAPLFTL 528
Query: 734 LNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPR 793
LNN VEI LDA KF+C+Y+RP+A R G S+ LPR
Sbjct: 529 LNNRVEIGLDAHKFLCKYQRPMAGRGWTSG---------------SDCSCWRPCELILPR 573
Query: 794 AYYRWTRAHDLRGFLNFTLARAPSSFAA--------AHNRTCRYRAFRDDDGHYSQTYWN 845
R + L G L R A RY+A RD + + YW
Sbjct: 574 TNARSRLGYWLNG-QGQILGRRRGGNAGFGVEIREPLQTPQPRYKASRDVGVNLALFYWK 632
Query: 846 LLA--IRLAFVIVFEHVVFSVGRLLDLLVPDIP 876
LLA + L F+I FE+VVF D LVPD+P
Sbjct: 633 LLAVHVHLGFIIAFENVVFFFLCPNDRLVPDVP 665
>gi|55741655 anoctamin 8 [Homo sapiens]
Length = 1232
Score = 121 bits (303), Expect = 3e-27
Identities = 115/430 (26%), Positives = 179/430 (41%), Gaps = 110/430 (25%)
Query: 249 FFTSTKRHQI----LFEILAKTPYGHEKKNLLG----IHQLLAEGVLSAAFPLHDGPFKT 300
FFTS +R I L + AK L I +L A G++ FP+H+
Sbjct: 159 FFTSQERQSIIRFWLQNLRAKQGEALHNVRFLEDQPIIPELAARGIIQQVFPVHE----- 213
Query: 301 PPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPA 360
R+ R L + W + N QPLD + YFG K+A+YFAWLGFYT ++
Sbjct: 214 -------QRILNR--LMKSWVQAVCEN--QPLDDICDYFGVKIAMYFAWLGFYTSAMVYP 262
Query: 361 AVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLCLDCPFWLLSSACALAQAGRLFDH 420
AV G++++ +A +
Sbjct: 263 AVFGSVLY-----------------------------------------TFTEADQTSRD 281
Query: 421 GGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYE-DTEERPRPQFAASAPMTAPNP 479
V F+LF +W+ L LE WKR+ A LAY+W D + E PRPQF + +P
Sbjct: 282 VSCVVFALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEPRPQFRG---VRRISP 338
Query: 480 ITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYR----AIMAIVVSRSGNT 535
IT +E Y+P R L +V + + + CLV + L + +V+S G
Sbjct: 339 ITRAEEFYYPPWKRLLFQL------LVSLPLCLACLVCVFLLMLGCFQLQELVLSVKG-- 390
Query: 536 LLAAWASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFIFQ 595
R+A V+ + + + ++ Y LA L E +R ++ +E +KV +FQ
Sbjct: 391 -----LPRLARFLPKVMLALLVSVSAEGYKKLAIWLNDMENYRLESAYEKHLIIKVVLFQ 445
Query: 596 FVNFYSSPVYIAFFKGRFVGYPGNYHTLFGVRNEECAAGGCLIELAQELLVIMVGKQVIN 655
FVN Y S YI F+ +++ E L + L +++ +Q +
Sbjct: 446 FVNSYLSLFYIGFY----------------LKDME--------RLKEMLATLLITRQFLQ 481
Query: 656 NMQEVLIPKL 665
N++EVL P L
Sbjct: 482 NVREVLQPHL 491
Score = 73.6 bits (179), Expect = 8e-13
Identities = 35/83 (42%), Positives = 52/83 (62%)
Query: 702 EGLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQD 761
E F +Y EM +QFG+V +F +A PLA L AL+NN +EIR DA K +RP +R +
Sbjct: 742 EDTFQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVES 801
Query: 762 IGIWFHILAGLTHLAVISNAFLL 784
IG W ++ + LA++ N +L+
Sbjct: 802 IGQWQKVMEAMGVLAIVVNCYLI 824
>gi|239741065 PREDICTED: hypothetical protein [Homo sapiens]
Length = 494
Score = 110 bits (276), Expect = 5e-24
Identities = 93/272 (34%), Positives = 120/272 (44%), Gaps = 62/272 (22%)
Query: 615 GYPGNYHTLFGVRNEECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFRL 674
G P + V ++C GGC I++ Q+L++IMVGKQ++N+M+E +
Sbjct: 217 GGPKALSKVLCVCQQQCGPGGCHIQVTQQLIIIMVGKQLLNHMEEFV------------- 263
Query: 675 RSKKRKAGASAGASQGPWEDDYELVPCEGLFDEYLEMVLQFGFVTIFVAACPLAPLFALL 734
G GP D PC LQFGF+TIFV A LAPLF LL
Sbjct: 264 -----------GLGGGPGPD----TPCLP--------ELQFGFITIFVGAFLLAPLFTLL 300
Query: 735 NNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRA 794
NN VEI LDA KF+C+Y+RP+A R G S+ LPR
Sbjct: 301 NNRVEIGLDAHKFLCKYQRPMAGRGWTSG---------------SDCSCWRPCELILPRT 345
Query: 795 YYRWTRAHDLRGFLNFTLARAPSSFAA--------AHNRTCRYRAFRDDDGHYSQTYWNL 846
R + L G L R A RY+A RD + + YW L
Sbjct: 346 NARSRLGYWLNG-QGQILGRRRGGNAGFGVEIREPLQTPQPRYKASRDVGVNLALFYWKL 404
Query: 847 LA--IRLAFVIVFEHVVFSVGRLLDLLVPDIP 876
LA + L F+I FE+VVF D LVPD+P
Sbjct: 405 LAVHVHLGFIIAFENVVFFFLCPNDRLVPDVP 436
Score = 96.7 bits (239), Expect = 9e-20
Identities = 56/158 (35%), Positives = 79/158 (50%), Gaps = 32/158 (20%)
Query: 417 LFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEERPRP---------- 466
LFDH GTVFFS+FM+ W L + SATLA+ WDCSD++D E P
Sbjct: 54 LFDHPGTVFFSIFMSFWGHGLPGALEAGSATLAHHWDCSDFQDQEAMPSSAPHHWDCSDF 113
Query: 467 ----------------------QFAASAPMTAPNPITGEDEPYFPERSRARRMLAGSVVI 504
+FAA A NP+TG EPYF S +L S I
Sbjct: 114 QDQEVMPSSALHHWDCSDFQDQEFAALALQMTQNPVTGLKEPYFQPHSCLSHLLTSSAAI 173
Query: 505 VVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWAS 542
+ ++ VV++ LVS+I+Y I++I + +GN++L A+
Sbjct: 174 LTVLCVVMIFLVSVIIYHGIISIAMFHTGNSVLMTQAN 211
>gi|25952092 potassium voltage-gated channel, shaker-related
subfamily, member 7 [Homo sapiens]
Length = 456
Score = 35.8 bits (81), Expect = 0.19
Identities = 22/55 (40%), Positives = 33/55 (60%), Gaps = 6/55 (10%)
Query: 488 FPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWAS 542
FPE S+A R+LA V+V++V++VV CL ++ +R R G L AA A+
Sbjct: 135 FPESSQAARVLAVVSVLVILVSIVVFCLETLPDFRD------DRDGTGLAAAAAA 183
>gi|22208951 ankyrin repeat and SOCS box-containing protein 3
isoform b [Homo sapiens]
Length = 445
Score = 32.7 bits (73), Expect = 1.6
Identities = 32/108 (29%), Positives = 44/108 (40%), Gaps = 28/108 (25%)
Query: 686 GASQGPWEDDYELV----PCEGLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVE-I 740
G S GPW YE V + + E+L +L GF PL L N+W++ +
Sbjct: 295 GCSLGPWNHIYEFVNHAIKAQAKYKEWLPHLLVAGF----------DPLILLCNSWIDSV 344
Query: 741 RLDARKFVCEYRR-----PVAER---AQDIGIWF---HI--LAGLTHL 775
+D F E+ P ER A+ W HI + LTHL
Sbjct: 345 SIDTLIFTLEFTNWKTLAPAVERMLSARASNAWILQQHIATVPSLTHL 392
>gi|7705831 ankyrin repeat and SOCS box-containing protein 3 isoform
a [Homo sapiens]
Length = 518
Score = 32.7 bits (73), Expect = 1.6
Identities = 32/108 (29%), Positives = 44/108 (40%), Gaps = 28/108 (25%)
Query: 686 GASQGPWEDDYELV----PCEGLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVE-I 740
G S GPW YE V + + E+L +L GF PL L N+W++ +
Sbjct: 368 GCSLGPWNHIYEFVNHAIKAQAKYKEWLPHLLVAGF----------DPLILLCNSWIDSV 417
Query: 741 RLDARKFVCEYRR-----PVAER---AQDIGIWF---HI--LAGLTHL 775
+D F E+ P ER A+ W HI + LTHL
Sbjct: 418 SIDTLIFTLEFTNWKTLAPAVERMLSARASNAWILQQHIATVPSLTHL 465
>gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 4 [Homo sapiens]
Length = 651
Score = 32.3 bits (72), Expect = 2.1
Identities = 20/59 (33%), Positives = 33/59 (55%), Gaps = 3/59 (5%)
Query: 466 PQFAASAPMTAPNPITG-EDEPYFPERSRARRMLAG--SVVIVVMVAVVVMCLVSIILY 521
P S+P T P +G ED+P P S + L VVI ++VAV+++ L+ ++L+
Sbjct: 422 PSGGPSSPTTGPTSTSGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLLLLLLF 480
>gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 1 [Homo sapiens]
Length = 650
Score = 32.3 bits (72), Expect = 2.1
Identities = 20/59 (33%), Positives = 33/59 (55%), Gaps = 3/59 (5%)
Query: 466 PQFAASAPMTAPNPITG-EDEPYFPERSRARRMLAG--SVVIVVMVAVVVMCLVSIILY 521
P S+P T P +G ED+P P S + L VVI ++VAV+++ L+ ++L+
Sbjct: 422 PSGGPSSPTTGPTSTSGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLLLLLLF 480
>gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B,
member 2 isoform 1 [Homo sapiens]
Length = 598
Score = 32.0 bits (71), Expect = 2.8
Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 4/60 (6%)
Query: 466 PQFAASAPMTAP--NPITGEDEPYFPERSRARRMLAG--SVVIVVMVAVVVMCLVSIILY 521
P +S P T P P ED+P P S + L VVI ++VAVV++ L+ ++L+
Sbjct: 421 PSMGSSPPPTGPISTPAGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVVLLLLLLLLLF 480
>gi|55743118 RAB3 GTPase-activating protein [Homo sapiens]
Length = 981
Score = 32.0 bits (71), Expect = 2.8
Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 2/104 (1%)
Query: 191 PLQELPNQASNWSAGLLAWLGIPNVLLEVVPDVPPEYYSCRFRVNKLPRFLGSDNQDTFF 250
P+ EL + A+ W L + + N + + + ++S R R + P+ L D FF
Sbjct: 275 PISEL-HLATTWPH-LTEGIIVDNDVYSDLDPIQAPHWSVRVRKAENPQCLLGDFVTEFF 332
Query: 251 TSTKRHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLH 294
+R + EIL ++ + E K I L++ A+ P+H
Sbjct: 333 KICRRKESTDEILGRSAFEEEGKETADITHALSKLTEPASVPIH 376
>gi|224549005 RNA binding motif protein 17 [Homo sapiens]
Length = 401
Score = 31.6 bits (70), Expect = 3.6
Identities = 16/48 (33%), Positives = 27/48 (56%), Gaps = 2/48 (4%)
Query: 456 DYEDTEERPRPQFAASAPMTAPNPITGEDEPYFPERSRARRMLAGSVV 503
+ E+ E+R + + AS P+P + EDE Y ER R +R + G+ +
Sbjct: 130 EIEEREKRRKDRHEASGFARRPDPDSDEDEDY--ERERRKRSMGGAAI 175
>gi|14249678 RNA binding motif protein 17 [Homo sapiens]
Length = 401
Score = 31.6 bits (70), Expect = 3.6
Identities = 16/48 (33%), Positives = 27/48 (56%), Gaps = 2/48 (4%)
Query: 456 DYEDTEERPRPQFAASAPMTAPNPITGEDEPYFPERSRARRMLAGSVV 503
+ E+ E+R + + AS P+P + EDE Y ER R +R + G+ +
Sbjct: 130 EIEEREKRRKDRHEASGFARRPDPDSDEDEDY--ERERRKRSMGGAAI 175
>gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B,
member 2 isoform 2 [Homo sapiens]
Length = 597
Score = 31.6 bits (70), Expect = 3.6
Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 3/59 (5%)
Query: 466 PQFAASAPMTAPNPITG-EDEPYFPERSRARRMLAG--SVVIVVMVAVVVMCLVSIILY 521
P +S P T P G ED+P P S + L VVI ++VAVV++ L+ ++L+
Sbjct: 421 PSMGSSPPPTGPISTPGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVVLLLLLLLLLF 479
>gi|239752866 PREDICTED: similar to hCG1997308 [Homo sapiens]
Length = 173
Score = 31.6 bits (70), Expect = 3.6
Identities = 31/107 (28%), Positives = 36/107 (33%), Gaps = 10/107 (9%)
Query: 9 AGLQGPPLPTL-------CPAVRTGLYCRDQAHAERWAMTSETSSGSHCARSRMLRRRAQ 61
A L PP+PTL CP + R A + S G R R R
Sbjct: 62 ASLTPPPVPTLQVAPEAPCPQSHLSFTSEGSSGTSRGA--TGKSMGHSSQRPVSSRARCW 119
Query: 62 EEDSTVLIDVSPPEAEKRGSYGSTAHASEPGGQQAAACRAGS-PAKP 107
L + E +K A EPG AAA A S PA P
Sbjct: 120 TRSGWRLKESGEEEEDKSSEAAQRCRAQEPGASSAAALLASSVPALP 166
>gi|239747418 PREDICTED: hypothetical protein XP_002346694 [Homo
sapiens]
Length = 173
Score = 31.6 bits (70), Expect = 3.6
Identities = 31/107 (28%), Positives = 36/107 (33%), Gaps = 10/107 (9%)
Query: 9 AGLQGPPLPTL-------CPAVRTGLYCRDQAHAERWAMTSETSSGSHCARSRMLRRRAQ 61
A L PP+PTL CP + R A + S G R R R
Sbjct: 62 ASLTPPPVPTLQVAPEAPCPQSHLSFTSEGSSGTSRGA--TGKSMGHSSQRPVSSRARCW 119
Query: 62 EEDSTVLIDVSPPEAEKRGSYGSTAHASEPGGQQAAACRAGS-PAKP 107
L + E +K A EPG AAA A S PA P
Sbjct: 120 TRSGWRLKESGEEEEDKSSEAAQRCRAQEPGASSAAALLASSVPALP 166
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,025,369
Number of Sequences: 37866
Number of extensions: 1697878
Number of successful extensions: 5993
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 5822
Number of HSP's gapped (non-prelim): 72
length of query: 933
length of database: 18,247,518
effective HSP length: 112
effective length of query: 821
effective length of database: 14,006,526
effective search space: 11499357846
effective search space used: 11499357846
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.