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Search of human proteins with 144446030
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|144446030 lymphocyte antigen 75 [Homo sapiens]
(1722 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|144446030 lymphocyte antigen 75 [Homo sapiens] 3692 0.0
gi|55953104 phospholipase A2 receptor 1 isoform 1 precursor [Hom... 809 0.0
gi|55953106 phospholipase A2 receptor 1 isoform 2 precursor [Hom... 792 0.0
gi|110624774 mannose receptor, C type 2 [Homo sapiens] 746 0.0
gi|57546917 mannose receptor, C type 1-like 1 [Homo sapiens] 536 e-152
gi|4505245 mannose receptor C type 1 precursor [Homo sapiens] 535 e-151
gi|26892293 CD302 molecule [Homo sapiens] 84 1e-15
gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens] 84 1e-15
gi|38372935 brevican isoform 1 [Homo sapiens] 75 4e-13
gi|126090892 aggrecan isoform 2 precursor [Homo sapiens] 70 1e-11
gi|126090883 aggrecan isoform 1 precursor [Homo sapiens] 68 7e-11
gi|187607300 versican isoform 2 [Homo sapiens] 67 1e-10
gi|21361116 versican isoform 1 [Homo sapiens] 67 1e-10
gi|29725633 regenerating islet-derived 1 alpha precursor [Homo s... 65 4e-10
gi|10835248 regenerating islet-derived 1 beta precursor [Homo sa... 65 7e-10
gi|18641360 collectin sub-family member 12 [Homo sapiens] 64 2e-09
gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens] 63 2e-09
gi|226823233 regenerating islet-derived family, member 4 isoform... 63 3e-09
gi|14042980 regenerating islet-derived family, member 4 isoform ... 63 3e-09
gi|38348296 C-type lectin domain family 4, member G [Homo sapiens] 62 5e-09
gi|33667103 C-type lectin, superfamily member 14 isoform 1 [Homo... 62 5e-09
gi|53832016 C-type lectin, superfamily member 14 isoform 2 [Homo... 62 5e-09
gi|20149533 Fc fragment of IgE, low affinity II, receptor for (C... 60 2e-08
gi|55742774 dectin-2 [Homo sapiens] 60 2e-08
gi|7657333 C-type lectin domain family 4, member E [Homo sapiens] 59 4e-08
gi|223029517 CD209 molecule isoform 8 [Homo sapiens] 59 5e-08
gi|223278347 C-type lectin domain family 4, member M isoform 9 [... 59 5e-08
gi|223278337 C-type lectin domain family 4, member M isoform 12 ... 59 5e-08
gi|223278335 C-type lectin domain family 4, member M isoform 2 [... 59 5e-08
gi|223029386 CD209 molecule isoform 3 [Homo sapiens] 59 5e-08
>gi|144446030 lymphocyte antigen 75 [Homo sapiens]
Length = 1722
Score = 3692 bits (9575), Expect = 0.0
Identities = 1722/1722 (100%), Positives = 1722/1722 (100%)
Query: 1 MRTGWATPRRPAGLLMLLFWFFDLAEPSGRAANDPFTIVHGNTGKCIKPVYGWIVADDCD 60
MRTGWATPRRPAGLLMLLFWFFDLAEPSGRAANDPFTIVHGNTGKCIKPVYGWIVADDCD
Sbjct: 1 MRTGWATPRRPAGLLMLLFWFFDLAEPSGRAANDPFTIVHGNTGKCIKPVYGWIVADDCD 60
Query: 61 ETEDKLWKWVSQHRLFHLHSQKCLGLDITKSVNELRMFSCDSSAMLWWKCEHHSLYGAAR 120
ETEDKLWKWVSQHRLFHLHSQKCLGLDITKSVNELRMFSCDSSAMLWWKCEHHSLYGAAR
Sbjct: 61 ETEDKLWKWVSQHRLFHLHSQKCLGLDITKSVNELRMFSCDSSAMLWWKCEHHSLYGAAR 120
Query: 121 YRLALKDGHGTAISNASDVWKKGGSEESLCDQPYHEIYTRDGNSYGRPCEFPFLIDGTWH 180
YRLALKDGHGTAISNASDVWKKGGSEESLCDQPYHEIYTRDGNSYGRPCEFPFLIDGTWH
Sbjct: 121 YRLALKDGHGTAISNASDVWKKGGSEESLCDQPYHEIYTRDGNSYGRPCEFPFLIDGTWH 180
Query: 181 HDCILDEDHSGPWCATTLNYEYDRKWGICLKPENGCEDNWEKNEQFGSCYQFNTQTALSW 240
HDCILDEDHSGPWCATTLNYEYDRKWGICLKPENGCEDNWEKNEQFGSCYQFNTQTALSW
Sbjct: 181 HDCILDEDHSGPWCATTLNYEYDRKWGICLKPENGCEDNWEKNEQFGSCYQFNTQTALSW 240
Query: 241 KEAYVSCQNQGADLLSINSAAELTYLKEKEGIAKIFWIGLNQLYSARGWEWSDHKPLNFL 300
KEAYVSCQNQGADLLSINSAAELTYLKEKEGIAKIFWIGLNQLYSARGWEWSDHKPLNFL
Sbjct: 241 KEAYVSCQNQGADLLSINSAAELTYLKEKEGIAKIFWIGLNQLYSARGWEWSDHKPLNFL 300
Query: 301 NWDPDRPSAPTIGGSSCARMDAESGLWQSFSCEAQLPYVCRKPLNNTVELTDVWTYSDTR 360
NWDPDRPSAPTIGGSSCARMDAESGLWQSFSCEAQLPYVCRKPLNNTVELTDVWTYSDTR
Sbjct: 301 NWDPDRPSAPTIGGSSCARMDAESGLWQSFSCEAQLPYVCRKPLNNTVELTDVWTYSDTR 360
Query: 361 CDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEE 420
CDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEE
Sbjct: 361 CDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEE 420
Query: 421 VWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYLGELGQWKVQSCEEK 480
VWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYLGELGQWKVQSCEEK
Sbjct: 421 VWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYLGELGQWKVQSCEEK 480
Query: 481 LKYVCKRKGEKLNDASSDKMCPPDEGWKRHGETCYKIYEDEVPFGTNCNLTITSRFEQEY 540
LKYVCKRKGEKLNDASSDKMCPPDEGWKRHGETCYKIYEDEVPFGTNCNLTITSRFEQEY
Sbjct: 481 LKYVCKRKGEKLNDASSDKMCPPDEGWKRHGETCYKIYEDEVPFGTNCNLTITSRFEQEY 540
Query: 541 LNDLMKKYDKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFLEPASPGGCVAM 600
LNDLMKKYDKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFLEPASPGGCVAM
Sbjct: 541 LNDLMKKYDKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFLEPASPGGCVAM 600
Query: 601 STGKSVGKWEVKDCRSFKALSICKKMSGPLGPEEASPKPDDPCPEGWQSFPASLSCYKVF 660
STGKSVGKWEVKDCRSFKALSICKKMSGPLGPEEASPKPDDPCPEGWQSFPASLSCYKVF
Sbjct: 601 STGKSVGKWEVKDCRSFKALSICKKMSGPLGPEEASPKPDDPCPEGWQSFPASLSCYKVF 660
Query: 661 HAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFLTDQFSGQHWLWIGLNKRSP 720
HAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFLTDQFSGQHWLWIGLNKRSP
Sbjct: 661 HAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFLTDQFSGQHWLWIGLNKRSP 720
Query: 721 DLQGSWQWSDRTPVSTIIMPNEFQQDYDIRDCAAVKVFHRPWRRGWHFYDDREFIYLRPF 780
DLQGSWQWSDRTPVSTIIMPNEFQQDYDIRDCAAVKVFHRPWRRGWHFYDDREFIYLRPF
Sbjct: 721 DLQGSWQWSDRTPVSTIIMPNEFQQDYDIRDCAAVKVFHRPWRRGWHFYDDREFIYLRPF 780
Query: 781 ACDTKLEWVCQIPKGRTPKTPDWYNPDRAGIHGPPLIIEGSEYWFVADLHLNYEEAVLYC 840
ACDTKLEWVCQIPKGRTPKTPDWYNPDRAGIHGPPLIIEGSEYWFVADLHLNYEEAVLYC
Sbjct: 781 ACDTKLEWVCQIPKGRTPKTPDWYNPDRAGIHGPPLIIEGSEYWFVADLHLNYEEAVLYC 840
Query: 841 ASNHSFLATITSFVGLKAIKNKIANISGDGQKWWIRISEWPIDDHFTYSRYPWHRFPVTF 900
ASNHSFLATITSFVGLKAIKNKIANISGDGQKWWIRISEWPIDDHFTYSRYPWHRFPVTF
Sbjct: 841 ASNHSFLATITSFVGLKAIKNKIANISGDGQKWWIRISEWPIDDHFTYSRYPWHRFPVTF 900
Query: 901 GEECLYMSAKTWLIDLGKPTDCSTKLPFICEKYNVSSLEKYSPDSAAKVQCSEQWIPFQN 960
GEECLYMSAKTWLIDLGKPTDCSTKLPFICEKYNVSSLEKYSPDSAAKVQCSEQWIPFQN
Sbjct: 901 GEECLYMSAKTWLIDLGKPTDCSTKLPFICEKYNVSSLEKYSPDSAAKVQCSEQWIPFQN 960
Query: 961 KCFLKIKPVSLTFSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATLWIGLRWTAYE 1020
KCFLKIKPVSLTFSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATLWIGLRWTAYE
Sbjct: 961 KCFLKIKPVSLTFSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATLWIGLRWTAYE 1020
Query: 1021 KINKWTDNRELTYSNFHPLLVSGRLRIPENFFEEESRYHCALILNLQKSPFTGTWNFTSC 1080
KINKWTDNRELTYSNFHPLLVSGRLRIPENFFEEESRYHCALILNLQKSPFTGTWNFTSC
Sbjct: 1021 KINKWTDNRELTYSNFHPLLVSGRLRIPENFFEEESRYHCALILNLQKSPFTGTWNFTSC 1080
Query: 1081 SERHFVSLCQKYSEVKSRQTLQNASETVKYLNNLYKIIPKTLTWHSAKRECLKSNMQLVS 1140
SERHFVSLCQKYSEVKSRQTLQNASETVKYLNNLYKIIPKTLTWHSAKRECLKSNMQLVS
Sbjct: 1081 SERHFVSLCQKYSEVKSRQTLQNASETVKYLNNLYKIIPKTLTWHSAKRECLKSNMQLVS 1140
Query: 1141 ITDPYQQAFLSVQALLHNSSLWIGLFSQDDELNFGWSDGKRLHFSRWAETNGQLEDCVVL 1200
ITDPYQQAFLSVQALLHNSSLWIGLFSQDDELNFGWSDGKRLHFSRWAETNGQLEDCVVL
Sbjct: 1141 ITDPYQQAFLSVQALLHNSSLWIGLFSQDDELNFGWSDGKRLHFSRWAETNGQLEDCVVL 1200
Query: 1201 DTDGFWKTVDCNDNQPGAICYYSGNETEKEVKPVDSVKCPSPVLNTPWIPFQNCCYNFII 1260
DTDGFWKTVDCNDNQPGAICYYSGNETEKEVKPVDSVKCPSPVLNTPWIPFQNCCYNFII
Sbjct: 1201 DTDGFWKTVDCNDNQPGAICYYSGNETEKEVKPVDSVKCPSPVLNTPWIPFQNCCYNFII 1260
Query: 1261 TKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNYMASWVMLGITYRN 1320
TKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNYMASWVMLGITYRN
Sbjct: 1261 TKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNYMASWVMLGITYRN 1320
Query: 1321 KSLMWFDKTPLSYTHWRAGRPTIKNEKFLAGLSTDGFWDIQTFKVIEEAVYFHQHSILAC 1380
KSLMWFDKTPLSYTHWRAGRPTIKNEKFLAGLSTDGFWDIQTFKVIEEAVYFHQHSILAC
Sbjct: 1321 KSLMWFDKTPLSYTHWRAGRPTIKNEKFLAGLSTDGFWDIQTFKVIEEAVYFHQHSILAC 1380
Query: 1381 KIEMVDYKEEYNTTLPQFMPYEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLF 1440
KIEMVDYKEEYNTTLPQFMPYEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLF
Sbjct: 1381 KIEMVDYKEEYNTTLPQFMPYEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLF 1440
Query: 1441 LEDIVKRDGFPLWVGLSSHDGSESSFEWSDGSTFDYIPWKGQTSPGNCVLLDPKGTWKHE 1500
LEDIVKRDGFPLWVGLSSHDGSESSFEWSDGSTFDYIPWKGQTSPGNCVLLDPKGTWKHE
Sbjct: 1441 LEDIVKRDGFPLWVGLSSHDGSESSFEWSDGSTFDYIPWKGQTSPGNCVLLDPKGTWKHE 1500
Query: 1501 KCNSVKDGAICYKPTKSKKLSRLTYSSRCPAAKENGSRWIQYKGHCYKSDQALHSFSEAK 1560
KCNSVKDGAICYKPTKSKKLSRLTYSSRCPAAKENGSRWIQYKGHCYKSDQALHSFSEAK
Sbjct: 1501 KCNSVKDGAICYKPTKSKKLSRLTYSSRCPAAKENGSRWIQYKGHCYKSDQALHSFSEAK 1560
Query: 1561 KLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRVWLGLSQHSVDQSWSWLDGSEVT 1620
KLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRVWLGLSQHSVDQSWSWLDGSEVT
Sbjct: 1561 KLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRVWLGLSQHSVDQSWSWLDGSEVT 1620
Query: 1621 FVKWENKSKSGVGRCSMLIASNETWKKVECEHGFGRVVCKVPLGPDYTAIAIIVATLSIL 1680
FVKWENKSKSGVGRCSMLIASNETWKKVECEHGFGRVVCKVPLGPDYTAIAIIVATLSIL
Sbjct: 1621 FVKWENKSKSGVGRCSMLIASNETWKKVECEHGFGRVVCKVPLGPDYTAIAIIVATLSIL 1680
Query: 1681 VLMGGLIWFLFQRHRLHLAGFSSVRYAQGVNEDEIMLPSFHD 1722
VLMGGLIWFLFQRHRLHLAGFSSVRYAQGVNEDEIMLPSFHD
Sbjct: 1681 VLMGGLIWFLFQRHRLHLAGFSSVRYAQGVNEDEIMLPSFHD 1722
>gi|55953104 phospholipase A2 receptor 1 isoform 1 precursor [Homo
sapiens]
Length = 1463
Score = 809 bits (2089), Expect = 0.0
Identities = 484/1378 (35%), Positives = 704/1378 (51%), Gaps = 105/1378 (7%)
Query: 36 FTIVHGNTGKCIKPVYGWIVADDCDET-EDKLWKWVSQHRLFHLHSQKCLGLDITKSVNE 94
F I + KCI+ + ++C + + LWKWVS H LF++ CLGL+ +
Sbjct: 41 FVIQSESLKKCIQAGKSVLTLENCKQANKHMLWKWVSNHGLFNIGGSGCLGLNFSAPEQP 100
Query: 95 LRMFSCDSSAM-LWWKCEHHSLYGAARYRLALKDGHGTAISNASDVWK---KGGSEESLC 150
L ++ CDS+ + L W+C + G +Y + + + T +++ + K G +C
Sbjct: 101 LSLYECDSTLVSLRWRCNRKMITGPLQYSVQVAHDN-TVVASRKYIHKWISYGSGGGDIC 159
Query: 151 DQPYHEIYTRDGNSYGRPCEFPFLIDGTWHHDCILD-EDHSGPWCATTLNYEYDRKWGIC 209
+ + +++T GN++G PC FPF + WHH+C + + WCATT YE D KWG C
Sbjct: 160 EYLHKDLHTIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFC 219
Query: 210 LKP---ENGCEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYL 266
P E GC+ WEK+ CYQFN ++LSW EA+ SCQ QG LLSI E ++
Sbjct: 220 PDPTSAEVGCDTIWEKDLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFI 279
Query: 267 KEKEGIAKI-FWIGLNQLYSARGWEWSDHKPLNFLNWDPDRPSAPTIGGSSCARMDAESG 325
+E + W+GLNQL GW+WSD PLN+LNW P+ P +
Sbjct: 280 REHMSSKTVEVWMGLNQLDEHAGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMPS 339
Query: 326 LWQSFSCEAQLPYVCRKPLNNT---VELTDVWTYSDTRCDAGWLPNNGFCYLLVNESNSW 382
W+S CE+ LPY+C+K LN+ + D W Y T C+ GW P N CY L E +W
Sbjct: 340 AWRSRDCESTLPYICKKYLNHIDHEIVEKDAWKYYATHCEPGWNPYNRNCYKLQKEEKTW 399
Query: 383 DKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEEVWIGLKNINIPTLFQWSDGTEV 442
+A C+A +S LI I SLA+VE +VT L +E+ E WIGL + IP F+WS+ + V
Sbjct: 400 HEALRSCQADNSALIDITSLAEVEFLVTLLGDENASE-TWIGLSSNKIPVSFEWSNDSSV 458
Query: 443 TLTYWDENEPNVPYNKTPNCVSYLGELGQWKVQSCEEKLKYVCKRKGEKLNDASSDKMCP 502
T W EP++ N++ CVS G WKV++CEE+L Y+CK+ G L+DA S C
Sbjct: 459 IFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEERLFYICKKAGHVLSDAESG--C- 515
Query: 503 PDEGWKRHGETCYKIYE-----DEVPFGTNCN---LTITSRFEQEYLNDLMKKYDKSLRK 554
EGW+RHG CYKI D+ G C +TIT+RFEQ ++ L+ K
Sbjct: 516 -QEGWERHGGFCYKIDTVLRSFDQASSGYYCPPALVTITNRFEQAFITSLISSVVKMKDS 574
Query: 555 YFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFLEPASPGGCVAMSTGKSVGKWEVKDC 614
YFW L+D + GEY W VG + V +++WN +P GGCVAM +G+WEVK C
Sbjct: 575 YFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPRYSGGCVAMRGRHPLGRWEVKHC 634
Query: 615 RSFKALSICKK-MSGPLGPEEASPKPDDPCPEGWQSFPASLSCYKVFHAERIVRKRNWEE 673
R FKA+S+CK+ + E P PC W+S P SC+KVFH+E+++ KR W E
Sbjct: 635 RHFKAMSLCKQPVENQEKAEYEERWPFHPCYLDWESEPGLASCFKVFHSEKVLMKRTWRE 694
Query: 674 AERFCQALGAHLSSFSHVDE---IKEFLHFLTDQFSGQHWLWIGLNKRSPDLQGSWQWSD 730
AE FC+ GAHL+SF+H++E + E LH + ++ + WIG NKR+P GSW+WSD
Sbjct: 695 AEAFCEEFGAHLASFAHIEEENFVNELLHSKFN-WTEERQFWIGFNKRNPLNAGSWEWSD 753
Query: 731 RTPVSTIIMPNEFQQDYDIRDCAAVKVFHRPWRRGWHFYDDREFIYLRPFACDTKLEWVC 790
RTPV + + N + + D R+CA K L P C +K EW+C
Sbjct: 754 RTPVVSSFLDNTYFGE-DARNCAVYKANKT----------------LLPLHCGSKREWIC 796
Query: 791 QIPKGRTPKTPDWYNPDRAGIHGPPLIIEGSEYWF--VADLHLNYEEAVLYCASNHSFLA 848
+IP+ PK P WY D P L + +EY F A LN+E C+ HS L
Sbjct: 797 KIPRDVKPKIPFWYQYD-----VPWLFYQDAEYLFHTFASEWLNFE---FVCSWLHSDLL 848
Query: 849 TITSFVGLKAIKNKIANISGDGQKWWIRISEWPIDDHFTYS------RYPW----HRFPV 898
TI S + I +KI +S G WWI + E +D F + W R
Sbjct: 849 TIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVN 908
Query: 899 TFGEECLYMSAKTWLIDLGKPTDCSTKLPFICEKYNVSSLEKYSPDSAAKVQCSEQWIPF 958
+ C ++S+ T L +CS +P IC++ V +EK C + W+ F
Sbjct: 909 NQSQRCGFISSIT---GLWGSEECSVSMPSICKRKKVWLIEKKKDTPKQHGTCPKGWLYF 965
Query: 959 QNKCFLKIKPVS----LTFSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATLWIGL 1014
KC L P ++ A C GGTL ++ S++EQ FIT L ++WIGL
Sbjct: 966 NYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTSVWIGL 1025
Query: 1015 RWTAYEKINKWTDNRELTYSNFHPLLVSGRLRIPENFFEEESRY--HCALILNLQKSPFT 1072
+ YE W + + + YSN+ P + + IP + E ++ CAL+ + FT
Sbjct: 1026 QNDDYE---TWLNGKPVVYSNWSPFDI---INIPSHNTTEVQKHIPLCALLSSNPNFHFT 1079
Query: 1073 GTWNFTSCSERHFVSLCQKYSEVK----SRQTLQNASETVKYLNNLYKIIPKTLTWHSAK 1128
G W F C + + +C+K + + + T++Y N YKII +TW++A
Sbjct: 1080 GKWYFEDCGKEGYGFVCEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAI 1139
Query: 1129 RECLKSNMQLVSITDPYQQAFLSVQALLHNSSLWIGLFSQDDELNFGWSDGKRLHFSRWA 1188
+ CL QLVSITD Y Q+FL+V + WIGLF+ D+ LNF WSDG + F+ W
Sbjct: 1140 KTCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHWIGLFTTDNGLNFDWSDGTKSSFTFWK 1199
Query: 1189 -ETNGQLEDCVVLDTDGFWKTVDCNDNQPGAICYYSGNETEKEVKPVDSVKCPSPVLNTP 1247
E + L DCV D++G W + C GAIC+ + E + S + P
Sbjct: 1200 DEESSLLGDCVFADSNGRWHSTACESFLQGAICHVPPETRQSEHPELCS------ETSIP 1253
Query: 1248 WIPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNY 1307
WI F++ CY+F + + + + H C+K S++L+I+DE EN F+LE+L F
Sbjct: 1254 WIKFKSNCYSFSTVLD---SMSFEAAHEFCKK--EGSNLLTIKDEAENAFLLEELFAFGS 1308
Query: 1308 MASWVMLGITY--RNKSLMWFDKTPLSYTHWRAGRPT---IKNEKFLAGLSTDGFWDI 1360
V L + N+++ WFD TP ++W +P K +A +G W +
Sbjct: 1309 SVQMVWLNAQFDGNNETIKWFDGTPTDQSNWGIRKPDTDYFKPHHCVALRIPEGLWQL 1366
Score = 157 bits (396), Expect = 1e-37
Identities = 188/850 (22%), Positives = 325/850 (38%), Gaps = 117/850 (13%)
Query: 930 CEKYNVSSLEKYSPDSAAKVQCSEQWIPFQNKCFLKIKP-----------------VSLT 972
C + SL K ++ K + E+W PF + C+L + + T
Sbjct: 634 CRHFKAMSLCKQPVENQEKAEYEERW-PF-HPCYLDWESEPGLASCFKVFHSEKVLMKRT 691
Query: 973 FSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDM-----EATLWIGLRWTAYEKINKWTD 1027
+ +A C +G L S E++F+ LL E WIG W
Sbjct: 692 WREAEAFCEEFGAHLASFAHIEEENFVNELLHSKFNWTEERQFWIGFNKRNPLNAGSWE- 750
Query: 1028 NRELTYSNFHPLLVSGRLRIPENFFEEESRYHCALILNLQKSPFTGTWNFTSC-SERHFV 1086
+S+ P++ S + +F E++R N P C S+R ++
Sbjct: 751 -----WSDRTPVVSSF---LDNTYFGEDARNCAVYKANKTLLPL-------HCGSKREWI 795
Query: 1087 SLCQKYSEVKSRQTLQNASETVKYLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITDPYQ 1146
+ + K Q + Y + Y W + + C + L++I ++
Sbjct: 796 CKIPRDVKPKIPFWYQYDVPWLFYQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHSAHE 855
Query: 1147 QAFL--SVQALL-HNSSLWIGLFSQDDELNFGWSDGKRLHFSRW-----AETNGQLEDCV 1198
Q F+ ++AL + +S WIGL + F W DG + + W N Q + C
Sbjct: 856 QEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRCG 915
Query: 1199 VLDT-DGFWKTVDCNDNQPGAICYYSGNET--EKEVKPVDSVKCPSPVLNTPWIPFQNCC 1255
+ + G W + +C+ + P +IC +K+ P CP W+ F C
Sbjct: 916 FISSITGLWGSEECSVSMP-SICKRKKVWLIEKKKDTPKQHGTCPKG-----WLYFNYKC 969
Query: 1256 YNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNYMASWVMLG 1315
I K+ ++ ++ H + +++I E E F+ L + + W+ L
Sbjct: 970 LLLNIPKDP--SSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNL-FGQTTSVWIGL- 1025
Query: 1316 ITYRNKSLMWFDKTPLSYTHWRA-------GRPTIKNEKFL---AGLSTD------GFWD 1359
+ W + P+ Y++W T + +K + A LS++ G W
Sbjct: 1026 --QNDDYETWLNGKPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTGKWY 1083
Query: 1360 IQTFKVIEEAVYFHQHSILACKIEMVDYKEEYNTTLPQFMPYEDGIYSVIQKKVTWYEAL 1419
+ +E F + V+ + Y +P + Y + Y +I +TWY A+
Sbjct: 1084 FEDCG--KEGYGFVCEKMQDTSGHGVNTSDMY--PMPNTLEYGNRTYKIINANMTWYAAI 1139
Query: 1420 NMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHDGSESSFEWSDGSTFDYIPW 1479
C L S+ +Q Q FL ++ R G+ W+GL + D +F+WSDG+ + W
Sbjct: 1140 KTCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHWIGLFTTDNG-LNFDWSDGTKSSFTFW 1198
Query: 1480 KGQTSP--GNCVLLDPKGTWKHEKCNSVKDGAICYKPTKSKKLSRLTYSSRCPAAKENGS 1537
K + S G+CV D G W C S GAIC+ P ++++ S E
Sbjct: 1199 KDEESSLLGDCVFADSNGRWHSTACESFLQGAICHVPPETRQ------SEHPELCSETSI 1252
Query: 1538 RWIQYKGHCYKSDQALH--SFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNIT 1595
WI++K +CY L SF A + C K + +++IKDE EN F+ + +
Sbjct: 1253 PWIKFKSNCYSFSTVLDSMSFEAAHEFCKK--EGSNLLTIKDEAENAFLLEELFAFGSSV 1310
Query: 1596 MRVWLGLSQHSVDQSWSWLDGSEVTFVKWENKSKS----GVGRCSMLIASNETWKKVECE 1651
VWL +++ W DG+ W + C L W+ C+
Sbjct: 1311 QMVWLNAQFDGNNETIKWFDGTPTDQSNWGIRKPDTDYFKPHHCVALRIPEGLWQLSPCQ 1370
Query: 1652 HGFGRVVCKVPL-----------GPDYTAIAIIVATLSILVLMGGLIWFLFQRHR----L 1696
G +CK+ GP ++ I + V I+++ + F +H
Sbjct: 1371 EKKG-FICKMEADIHTAEALPEKGPSHSIIPLAVVLTLIVIVAICTLSFCIYKHNGGFFR 1429
Query: 1697 HLAGFSSVRY 1706
LAGF + Y
Sbjct: 1430 RLAGFRNPYY 1439
Score = 150 bits (379), Expect = 1e-35
Identities = 254/1104 (23%), Positives = 427/1104 (38%), Gaps = 181/1104 (16%)
Query: 643 CPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFLT 702
C W+ S CY+ ++ +W EA CQ G L S + DE +E +F+
Sbjct: 229 CDTIWEKDLNSHICYQF----NLLSSLSWSEAHSSCQMQGGTLLSIT--DETEE--NFIR 280
Query: 703 DQFSGQHW-LWIGLNKRSPDLQGSWQWSDRTPVSTIIMPNEFQQDYDIRD-CAAVKVFH- 759
+ S + +W+GLN+ D WQWSD TP++ + E + + D C F
Sbjct: 281 EHMSSKTVEVWMGLNQL--DEHAGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMP 338
Query: 760 RPWRRGWHFYDDREFIYLRPFACDTKLEWVCQ--IPKGR-----TPKTPDWYNPDRAGIH 812
WR R+ P+ C L + + K T P W NP +
Sbjct: 339 SAWR-------SRDCESTLPYICKKYLNHIDHEIVEKDAWKYYATHCEPGW-NPYNRNCY 390
Query: 813 GPPLIIEGSEYWFVADLHLNYEEAVLYCASNHSFLATITSFVGLKAIKNKIANISGDGQK 872
+ + + W EA+ C +++S L ITS ++ + + + + +
Sbjct: 391 K---LQKEEKTW---------HEALRSCQADNSALIDITSLAEVEFLVTLLGD--ENASE 436
Query: 873 WWIRIS--------EWPIDDHFTYSRYPWHRF-PVTFGEECLYMSAKTWLIDLGKPTDCS 923
WI +S EW D ++ WH P F + K +C
Sbjct: 437 TWIGLSSNKIPVSFEWSNDSSVIFTN--WHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCE 494
Query: 924 TKLPFICEKYNVSSLEKYSPDSAAKVQCSEQWIPFQNKCFLKIKPVSLTFSQASDTCHSY 983
+L +IC+K S A+ C E W C+ KI V +F QAS +
Sbjct: 495 ERLFYICKKAGHVL-------SDAESGCQEGWERHGGFCY-KIDTVLRSFDQASSGYYC- 545
Query: 984 GGTLPSVLSQIEQDFITSLLPDM----EATLWIGLRWT------AYEKINKWTDNRELTY 1033
L ++ ++ EQ FITSL+ + ++ WI L+ ++ + + + + T+
Sbjct: 546 PPALVTITNRFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTH 605
Query: 1034 SNFHPLLVSG-----RLRIPENFFE-EESRYHCALIL------NLQKSPFTGTWNFTSCS 1081
N H SG R R P +E + R+ A+ L N +K+ + W F C
Sbjct: 606 WNTHQPRYSGGCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWPFHPC- 664
Query: 1082 ERHFVSLCQKYSEVKSRQTLQNASETVKYLNNLYKIIPKTLTWHSAKRECLKSNMQLVSI 1141
Y + +S L + + + K++ K TW A+ C + L S
Sbjct: 665 ----------YLDWESEPGLASCFKVF----HSEKVLMKR-TWREAEAFCEEFGAHLASF 709
Query: 1142 TDPYQQAFLSVQALLHNS-------SLWIGLFSQDDELNFG---WSDGKRLHFSRWAET- 1190
++ F V LLH+ WIG F++ + LN G WSD + S T
Sbjct: 710 AHIEEENF--VNELLHSKFNWTEERQFWIG-FNKRNPLNAGSWEWSDRTPVVSSFLDNTY 766
Query: 1191 -NGQLEDCVVLDTDGFWKTVDCNDNQPGAICYYSGNETEKEVKPVDSVKCPSPV-LNTPW 1248
+C V + + C + IC + ++VKP K P + PW
Sbjct: 767 FGEDARNCAVYKANKTLLPLHCGSKREW-IC-----KIPRDVKP----KIPFWYQYDVPW 816
Query: 1249 IPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFN-Y 1307
+ +Q+ Y F A+ C L+ S +L+I E F+ ++ + Y
Sbjct: 817 LFYQDAEYLF-----HTFASEWLNFEFVCSWLH--SDLLTIHSAHEQEFIHSKIKALSKY 869
Query: 1308 MASW-VMLGITYRNKSLMWFDKTPLSYTHWRAGRP-TIKNEKFLAGL--STDGFWDIQTF 1363
ASW + L N W D TP+ Y +W GR T+ N+ G S G W +
Sbjct: 870 GASWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRCGFISSITGLWGSEEC 929
Query: 1364 KVIEEAVYFHQHSILACKIEMVDYKEE---YNTTLPQ---FMPYEDGIYSVIQKKVTWYE 1417
V ++ + K+ +++ K++ + T P+ + Y+ + ++ + +W
Sbjct: 930 SVSMPSICKRK------KVWLIEKKKDTPKQHGTCPKGWLYFNYKCLLLNIPKDPSSWKN 983
Query: 1418 ---ALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHDG----SESSFEWSD 1470
A + C++ GG L ++ ++ Q F+ + +W+GL + D + +S+
Sbjct: 984 WTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTSVWIGLQNDDYETWLNGKPVVYSN 1043
Query: 1471 GSTFDY--IPWKGQTSPGN----CVLLDPK------GTWKHEKCNSVKDGAICYKPTKSK 1518
S FD IP T C LL G W E C G +C K +
Sbjct: 1044 WSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTGKWYFEDCGKEGYGFVCEK-MQDT 1102
Query: 1519 KLSRLTYSSRCPAAKENGSRWIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDE 1578
+ S P ++Y YK A ++ A K C H A +VSI D+
Sbjct: 1103 SGHGVNTSDMYPMPNT-----LEYGNRTYKIINANMTWYAAIKTCLM--HKAQLVSITDQ 1155
Query: 1579 DENKFVSRLMRENNNITMRVWLGLSQHSVDQSWSWLDGSEVTFVKWENKSKSGVGRCSML 1638
F++ ++ N + W+GL ++ W DG++ +F W+++ S +G C +
Sbjct: 1156 YHQSFLTVVL---NRLGYAHWIGLFTTDNGLNFDWSDGTKSSFTFWKDEESSLLGDC-VF 1211
Query: 1639 IASNETWKKVECEHGFGRVVCKVP 1662
SN W CE +C VP
Sbjct: 1212 ADSNGRWHSTACESFLQGAICHVP 1235
Score = 89.7 bits (221), Expect = 2e-17
Identities = 108/458 (23%), Positives = 180/458 (39%), Gaps = 62/458 (13%)
Query: 1239 CPSPV-----LNTPWIPFQNC--CYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRD 1291
CP P +T W N CY F N + + E H+ CQ +LSI D
Sbjct: 219 CPDPTSAEVGCDTIWEKDLNSHICYQF----NLLSSLSWSEAHSSCQMQG--GTLLSITD 272
Query: 1292 EKENNFVLEQLLYFNYMASWVMLGITYRNKSLMWFDKTPLSYTHWRAGRPTIKNEKFL-- 1349
E E NF+ E + + W+ L + W D TPL+Y +W P + E F+
Sbjct: 273 ETEENFIREHMSS-KTVEVWMGLNQLDEHAGWQWSDGTPLNYLNWS---PEVNFEPFVED 328
Query: 1350 -AGLSTDGFWDIQTFKVIEEAV-YFHQHSILACKIEMVD---YKEEYNTTLPQFMPYEDG 1404
G + + E + Y + + E+V+ +K P + PY
Sbjct: 329 HCGTFSSFMPSAWRSRDCESTLPYICKKYLNHIDHEIVEKDAWKYYATHCEPGWNPYNRN 388
Query: 1405 IYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLEDIV-KRDGFPLWVGLSSHDGSE 1463
Y + +++ TW+EAL C L + + FL ++ + W+GLSS+
Sbjct: 389 CYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASETWIGLSSNK-IP 447
Query: 1464 SSFEWSDGSTFDYIPW---KGQTSPGN---CVLLD-PKGTWKHEKCNSVKDGAICYKPTK 1516
SFEWS+ S+ + W + P CV + +G WK + C + IC K
Sbjct: 448 VSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEE-RLFYICKK--- 503
Query: 1517 SKKLSRLTYSSRCPAAKENGSR--WIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVS 1574
+ + E+G + W ++ G CYK D L SF +A S + +V+
Sbjct: 504 ---------AGHVLSDAESGCQEGWERHGGFCYKIDTVLRSFDQAS---SGYYCPPALVT 551
Query: 1575 IKDEDENKFVSRLMRENNNITMR---VWLGLSQHSVDQSWSWLDGSE----VTFVKWENK 1627
I + E F++ L+ ++ + M+ W+ L + ++W + V + W
Sbjct: 552 ITNRFEQAFITSLI--SSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTH 609
Query: 1628 SKSGVGRCSMLIASNE--TWKKVECEHGFGRVVCKVPL 1663
G C + + W+ C H +CK P+
Sbjct: 610 QPRYSGGCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPV 647
Score = 81.6 bits (200), Expect = 6e-15
Identities = 66/258 (25%), Positives = 113/258 (43%), Gaps = 13/258 (5%)
Query: 238 LSWKEAYVSCQNQGADLLSINSAAE---LTYLKEKEGIAKIFWIGLNQLYSARGWEWSDH 294
++W A +C A L+SI LT + + G A WIGL + ++WSD
Sbjct: 1133 MTWYAAIKTCLMHKAQLVSITDQYHQSFLTVVLNRLGYAH--WIGLFTTDNGLNFDWSDG 1190
Query: 295 KPLNFLNWDPDRPSAPTIGGSSCARMDAESGLWQSFSCEAQLP-YVCRKPLNNTVELTDV 353
+F W + S C D+ +G W S +CE+ L +C P T +
Sbjct: 1191 TKSSFTFWKDEESSLL----GDCVFADS-NGRWHSTACESFLQGAICHVP-PETRQSEHP 1244
Query: 354 WTYSDTRCDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLH 413
S+T +N + + V +S S++ AH CK S+L++I A+ ++ +L
Sbjct: 1245 ELCSETSIPWIKFKSNCYSFSTVLDSMSFEAAHEFCKKEGSNLLTIKDEAENAFLLEELF 1304
Query: 414 NEDIKEE-VWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYLGELGQW 472
+ VW+ + +W DGT + W +P+ Y K +CV+ G W
Sbjct: 1305 AFGSSVQMVWLNAQFDGNNETIKWFDGTPTDQSNWGIRKPDTDYFKPHHCVALRIPEGLW 1364
Query: 473 KVQSCEEKLKYVCKRKGE 490
++ C+EK ++CK + +
Sbjct: 1365 QLSPCQEKKGFICKMEAD 1382
>gi|55953106 phospholipase A2 receptor 1 isoform 2 precursor [Homo
sapiens]
Length = 1324
Score = 792 bits (2045), Expect = 0.0
Identities = 473/1335 (35%), Positives = 684/1335 (51%), Gaps = 100/1335 (7%)
Query: 36 FTIVHGNTGKCIKPVYGWIVADDCDET-EDKLWKWVSQHRLFHLHSQKCLGLDITKSVNE 94
F I + KCI+ + ++C + + LWKWVS H LF++ CLGL+ +
Sbjct: 41 FVIQSESLKKCIQAGKSVLTLENCKQANKHMLWKWVSNHGLFNIGGSGCLGLNFSAPEQP 100
Query: 95 LRMFSCDSSAM-LWWKCEHHSLYGAARYRLALKDGHGTAISNASDVWK---KGGSEESLC 150
L ++ CDS+ + L W+C + G +Y + + + T +++ + K G +C
Sbjct: 101 LSLYECDSTLVSLRWRCNRKMITGPLQYSVQVAHDN-TVVASRKYIHKWISYGSGGGDIC 159
Query: 151 DQPYHEIYTRDGNSYGRPCEFPFLIDGTWHHDCILD-EDHSGPWCATTLNYEYDRKWGIC 209
+ + +++T GN++G PC FPF + WHH+C + + WCATT YE D KWG C
Sbjct: 160 EYLHKDLHTIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFC 219
Query: 210 LKP---ENGCEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYL 266
P E GC+ WEK+ CYQFN ++LSW EA+ SCQ QG LLSI E ++
Sbjct: 220 PDPTSAEVGCDTIWEKDLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFI 279
Query: 267 KEKEGIAKI-FWIGLNQLYSARGWEWSDHKPLNFLNWDPDRPSAPTIGGSSCARMDAESG 325
+E + W+GLNQL GW+WSD PLN+LNW P+ P +
Sbjct: 280 REHMSSKTVEVWMGLNQLDEHAGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMPS 339
Query: 326 LWQSFSCEAQLPYVCRKPLNNT---VELTDVWTYSDTRCDAGWLPNNGFCYLLVNESNSW 382
W+S CE+ LPY+C+K LN+ + D W Y T C+ GW P N CY L E +W
Sbjct: 340 AWRSRDCESTLPYICKKYLNHIDHEIVEKDAWKYYATHCEPGWNPYNRNCYKLQKEEKTW 399
Query: 383 DKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEEVWIGLKNINIPTLFQWSDGTEV 442
+A C+A +S LI I SLA+VE +VT L +E+ E WIGL + IP F+WS+ + V
Sbjct: 400 HEALRSCQADNSALIDITSLAEVEFLVTLLGDENASE-TWIGLSSNKIPVSFEWSNDSSV 458
Query: 443 TLTYWDENEPNVPYNKTPNCVSYLGELGQWKVQSCEEKLKYVCKRKGEKLNDASSDKMCP 502
T W EP++ N++ CVS G WKV++CEE+L Y+CK+ G L+DA S C
Sbjct: 459 IFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEERLFYICKKAGHVLSDAESG--C- 515
Query: 503 PDEGWKRHGETCYKIYE-----DEVPFGTNCN---LTITSRFEQEYLNDLMKKYDKSLRK 554
EGW+RHG CYKI D+ G C +TIT+RFEQ ++ L+ K
Sbjct: 516 -QEGWERHGGFCYKIDTVLRSFDQASSGYYCPPALVTITNRFEQAFITSLISSVVKMKDS 574
Query: 555 YFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFLEPASPGGCVAMSTGKSVGKWEVKDC 614
YFW L+D + GEY W VG + V +++WN +P GGCVAM +G+WEVK C
Sbjct: 575 YFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPRYSGGCVAMRGRHPLGRWEVKHC 634
Query: 615 RSFKALSICKK-MSGPLGPEEASPKPDDPCPEGWQSFPASLSCYKVFHAERIVRKRNWEE 673
R FKA+S+CK+ + E P PC W+S P SC+KVFH+E+++ KR W E
Sbjct: 635 RHFKAMSLCKQPVENQEKAEYEERWPFHPCYLDWESEPGLASCFKVFHSEKVLMKRTWRE 694
Query: 674 AERFCQALGAHLSSFSHVDE---IKEFLHFLTDQFSGQHWLWIGLNKRSPDLQGSWQWSD 730
AE FC+ GAHL+SF+H++E + E LH + ++ + WIG NKR+P GSW+WSD
Sbjct: 695 AEAFCEEFGAHLASFAHIEEENFVNELLHSKFN-WTEERQFWIGFNKRNPLNAGSWEWSD 753
Query: 731 RTPVSTIIMPNEFQQDYDIRDCAAVKVFHRPWRRGWHFYDDREFIYLRPFACDTKLEWVC 790
RTPV + + N + + D R+CA K L P C +K EW+C
Sbjct: 754 RTPVVSSFLDNTYFGE-DARNCAVYKANKT----------------LLPLHCGSKREWIC 796
Query: 791 QIPKGRTPKTPDWYNPDRAGIHGPPLIIEGSEYWF--VADLHLNYEEAVLYCASNHSFLA 848
+IP+ PK P WY D P L + +EY F A LN+E C+ HS L
Sbjct: 797 KIPRDVKPKIPFWYQYD-----VPWLFYQDAEYLFHTFASEWLNFE---FVCSWLHSDLL 848
Query: 849 TITSFVGLKAIKNKIANISGDGQKWWIRISEWPIDDHFTYS------RYPW----HRFPV 898
TI S + I +KI +S G WWI + E +D F + W R
Sbjct: 849 TIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVN 908
Query: 899 TFGEECLYMSAKTWLIDLGKPTDCSTKLPFICEKYNVSSLEKYSPDSAAKVQCSEQWIPF 958
+ C ++S+ T L +CS +P IC++ V +EK C + W+ F
Sbjct: 909 NQSQRCGFISSIT---GLWGSEECSVSMPSICKRKKVWLIEKKKDTPKQHGTCPKGWLYF 965
Query: 959 QNKCFLKIKPVS----LTFSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATLWIGL 1014
KC L P ++ A C GGTL ++ S++EQ FIT L ++WIGL
Sbjct: 966 NYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTSVWIGL 1025
Query: 1015 RWTAYEKINKWTDNRELTYSNFHPLLVSGRLRIPENFFEEESRY--HCALILNLQKSPFT 1072
+ YE W + + + YSN+ P + + IP + E ++ CAL+ + FT
Sbjct: 1026 QNDDYE---TWLNGKPVVYSNWSPFDI---INIPSHNTTEVQKHIPLCALLSSNPNFHFT 1079
Query: 1073 GTWNFTSCSERHFVSLCQKYSEVK----SRQTLQNASETVKYLNNLYKIIPKTLTWHSAK 1128
G W F C + + +C+K + + + T++Y N YKII +TW++A
Sbjct: 1080 GKWYFEDCGKEGYGFVCEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAI 1139
Query: 1129 RECLKSNMQLVSITDPYQQAFLSVQALLHNSSLWIGLFSQDDELNFGWSDGKRLHFSRWA 1188
+ CL QLVSITD Y Q+FL+V + WIGLF+ D+ LNF WSDG + F+ W
Sbjct: 1140 KTCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHWIGLFTTDNGLNFDWSDGTKSSFTFWK 1199
Query: 1189 -ETNGQLEDCVVLDTDGFWKTVDCNDNQPGAICYYSGNETEKEVKPVDSVKCPSPVLNTP 1247
E + L DCV D++G W + C GAIC+ + E + S + P
Sbjct: 1200 DEESSLLGDCVFADSNGRWHSTACESFLQGAICHVPPETRQSEHPELCS------ETSIP 1253
Query: 1248 WIPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNY 1307
WI F++ CY+F + + + + H C+K S++L+I+DE EN F+LE+L F
Sbjct: 1254 WIKFKSNCYSFSTVLD---SMSFEAAHEFCKK--EGSNLLTIKDEAENAFLLEELFAFGS 1308
Query: 1308 MASWVMLGITYRNKS 1322
V L + S
Sbjct: 1309 SVQMVWLNAQFDGNS 1323
Score = 150 bits (379), Expect = 1e-35
Identities = 255/1104 (23%), Positives = 426/1104 (38%), Gaps = 181/1104 (16%)
Query: 643 CPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFLT 702
C W+ S CY+ ++ +W EA CQ G L S + DE +E +F+
Sbjct: 229 CDTIWEKDLNSHICYQF----NLLSSLSWSEAHSSCQMQGGTLLSIT--DETEE--NFIR 280
Query: 703 DQFSGQHW-LWIGLNKRSPDLQGSWQWSDRTPVSTIIMPNEFQQDYDIRD-CAAVKVFH- 759
+ S + +W+GLN+ D WQWSD TP++ + E + + D C F
Sbjct: 281 EHMSSKTVEVWMGLNQL--DEHAGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMP 338
Query: 760 RPWRRGWHFYDDREFIYLRPFACDTKLEWVCQ--IPKGR-----TPKTPDWYNPDRAGIH 812
WR R+ P+ C L + + K T P W NP +
Sbjct: 339 SAWR-------SRDCESTLPYICKKYLNHIDHEIVEKDAWKYYATHCEPGW-NPYNRNCY 390
Query: 813 GPPLIIEGSEYWFVADLHLNYEEAVLYCASNHSFLATITSFVGLKAIKNKIANISGDGQK 872
+ + + W EA+ C +++S L ITS ++ + + + + +
Sbjct: 391 K---LQKEEKTW---------HEALRSCQADNSALIDITSLAEVEFLVTLLGD--ENASE 436
Query: 873 WWIRIS--------EWPIDDHFTYSRYPWHRF-PVTFGEECLYMSAKTWLIDLGKPTDCS 923
WI +S EW D ++ WH P F + K +C
Sbjct: 437 TWIGLSSNKIPVSFEWSNDSSVIFTN--WHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCE 494
Query: 924 TKLPFICEKYNVSSLEKYSPDSAAKVQCSEQWIPFQNKCFLKIKPVSLTFSQASDTCHSY 983
+L +IC+K S A+ C E W C+ KI V +F QAS +
Sbjct: 495 ERLFYICKKAGHVL-------SDAESGCQEGWERHGGFCY-KIDTVLRSFDQASSGYYC- 545
Query: 984 GGTLPSVLSQIEQDFITSLLPDM----EATLWIGLRWT------AYEKINKWTDNRELTY 1033
L ++ ++ EQ FITSL+ + ++ WI L+ ++ + + + + T+
Sbjct: 546 PPALVTITNRFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTH 605
Query: 1034 SNFHPLLVSG-----RLRIPENFFE-EESRYHCALIL------NLQKSPFTGTWNFTSCS 1081
N H SG R R P +E + R+ A+ L N +K+ + W F C
Sbjct: 606 WNTHQPRYSGGCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWPFHPC- 664
Query: 1082 ERHFVSLCQKYSEVKSRQTLQNASETVKYLNNLYKIIPKTLTWHSAKRECLKSNMQLVSI 1141
Y + +S L + + + K++ K TW A+ C + L S
Sbjct: 665 ----------YLDWESEPGLASCFKVF----HSEKVLMKR-TWREAEAFCEEFGAHLASF 709
Query: 1142 TDPYQQAFLSVQALLHNS-------SLWIGLFSQDDELNFG---WSDGKRLHFSRWAET- 1190
++ F V LLH+ WIG F++ + LN G WSD + S T
Sbjct: 710 AHIEEENF--VNELLHSKFNWTEERQFWIG-FNKRNPLNAGSWEWSDRTPVVSSFLDNTY 766
Query: 1191 -NGQLEDCVVLDTDGFWKTVDCNDNQPGAICYYSGNETEKEVKPVDSVKCPSPV-LNTPW 1248
+C V + + C + IC + ++VKP K P + PW
Sbjct: 767 FGEDARNCAVYKANKTLLPLHCGSKREW-IC-----KIPRDVKP----KIPFWYQYDVPW 816
Query: 1249 IPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFN-Y 1307
+ +Q+ Y F A+ C L+ S +L+I E F+ ++ + Y
Sbjct: 817 LFYQDAEYLF-----HTFASEWLNFEFVCSWLH--SDLLTIHSAHEQEFIHSKIKALSKY 869
Query: 1308 MASW-VMLGITYRNKSLMWFDKTPLSYTHWRAGRP-TIKNEKFLAGL--STDGFWDIQTF 1363
ASW + L N W D TP+ Y +W GR T+ N+ G S G W +
Sbjct: 870 GASWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRCGFISSITGLWGSEEC 929
Query: 1364 KVIEEAVYFHQHSILACKIEMVDYKEE---YNTTLPQ---FMPYEDGIYSVIQKKVTWYE 1417
V ++ + K+ +++ K++ + T P+ + Y+ + ++ + +W
Sbjct: 930 SVSMPSICKRK------KVWLIEKKKDTPKQHGTCPKGWLYFNYKCLLLNIPKDPSSWKN 983
Query: 1418 ---ALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHDGSE----SSFEWSD 1470
A + C++ GG L ++ ++ Q F+ + +W+GL + D +S+
Sbjct: 984 WTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTSVWIGLQNDDYETWLNGKPVVYSN 1043
Query: 1471 GSTFDYI--PWKGQTSPGN----CVLLDPK------GTWKHEKCNSVKDGAICYKPTKSK 1518
S FD I P T C LL G W E C G +C K +
Sbjct: 1044 WSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTGKWYFEDCGKEGYGFVCEKMQDTS 1103
Query: 1519 KLSRLTYSSRCPAAKENGSRWIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDE 1578
T S P ++Y YK A ++ A K C H A +VSI D+
Sbjct: 1104 GHGVNT-SDMYPMPNT-----LEYGNRTYKIINANMTWYAAIKTCLMH--KAQLVSITDQ 1155
Query: 1579 DENKFVSRLMRENNNITMRVWLGLSQHSVDQSWSWLDGSEVTFVKWENKSKSGVGRCSML 1638
F++ ++ N + W+GL ++ W DG++ +F W+++ S +G C +
Sbjct: 1156 YHQSFLTVVL---NRLGYAHWIGLFTTDNGLNFDWSDGTKSSFTFWKDEESSLLGDC-VF 1211
Query: 1639 IASNETWKKVECEHGFGRVVCKVP 1662
SN W CE +C VP
Sbjct: 1212 ADSNGRWHSTACESFLQGAICHVP 1235
Score = 143 bits (360), Expect = 2e-33
Identities = 165/725 (22%), Positives = 284/725 (39%), Gaps = 97/725 (13%)
Query: 930 CEKYNVSSLEKYSPDSAAKVQCSEQWIPFQNKCFLKIKP-----------------VSLT 972
C + SL K ++ K + E+W PF + C+L + + T
Sbjct: 634 CRHFKAMSLCKQPVENQEKAEYEERW-PF-HPCYLDWESEPGLASCFKVFHSEKVLMKRT 691
Query: 973 FSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDM-----EATLWIGLRWTAYEKINKWTD 1027
+ +A C +G L S E++F+ LL E WIG W
Sbjct: 692 WREAEAFCEEFGAHLASFAHIEEENFVNELLHSKFNWTEERQFWIGFNKRNPLNAGSWE- 750
Query: 1028 NRELTYSNFHPLLVSGRLRIPENFFEEESRYHCALILNLQKSPFTGTWNFTSC-SERHFV 1086
+S+ P++ S + +F E++R N P C S+R ++
Sbjct: 751 -----WSDRTPVVSSF---LDNTYFGEDARNCAVYKANKTLLPL-------HCGSKREWI 795
Query: 1087 SLCQKYSEVKSRQTLQNASETVKYLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITDPYQ 1146
+ + K Q + Y + Y W + + C + L++I ++
Sbjct: 796 CKIPRDVKPKIPFWYQYDVPWLFYQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHSAHE 855
Query: 1147 QAFL--SVQALL-HNSSLWIGLFSQDDELNFGWSDGKRLHFSRW-----AETNGQLEDCV 1198
Q F+ ++AL + +S WIGL + F W DG + + W N Q + C
Sbjct: 856 QEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRCG 915
Query: 1199 VLDT-DGFWKTVDCNDNQPGAICYYSGNET--EKEVKPVDSVKCPSPVLNTPWIPFQNCC 1255
+ + G W + +C+ + P +IC +K+ P CP W+ F C
Sbjct: 916 FISSITGLWGSEECSVSMP-SICKRKKVWLIEKKKDTPKQHGTCPKG-----WLYFNYKC 969
Query: 1256 YNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNYMASWVMLG 1315
I K+ ++ ++ H + +++I E E F+ L + + W+ L
Sbjct: 970 LLLNIPKDP--SSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNL-FGQTTSVWIGL- 1025
Query: 1316 ITYRNKSLMWFDKTPLSYTHWRA-------GRPTIKNEKFL---AGLSTD------GFWD 1359
+ W + P+ Y++W T + +K + A LS++ G W
Sbjct: 1026 --QNDDYETWLNGKPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTGKWY 1083
Query: 1360 IQTFKVIEEAVYFHQHSILACKIEMVDYKEEYNTTLPQFMPYEDGIYSVIQKKVTWYEAL 1419
+ +E F + V+ + Y +P + Y + Y +I +TWY A+
Sbjct: 1084 FEDCG--KEGYGFVCEKMQDTSGHGVNTSDMY--PMPNTLEYGNRTYKIINANMTWYAAI 1139
Query: 1420 NMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHDGSESSFEWSDGSTFDYIPW 1479
C L S+ +Q Q FL ++ R G+ W+GL + D +F+WSDG+ + W
Sbjct: 1140 KTCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHWIGLFTTDNG-LNFDWSDGTKSSFTFW 1198
Query: 1480 KGQTSP--GNCVLLDPKGTWKHEKCNSVKDGAICYKPTKSKKLSRLTYSSRCPAAKENGS 1537
K + S G+CV D G W C S GAIC+ P ++++ S E
Sbjct: 1199 KDEESSLLGDCVFADSNGRWHSTACESFLQGAICHVPPETRQ------SEHPELCSETSI 1252
Query: 1538 RWIQYKGHCYKSDQALH--SFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNIT 1595
WI++K +CY L SF A + C K + +++IKDE EN F+ + +
Sbjct: 1253 PWIKFKSNCYSFSTVLDSMSFEAAHEFCKK--EGSNLLTIKDEAENAFLLEELFAFGSSV 1310
Query: 1596 MRVWL 1600
VWL
Sbjct: 1311 QMVWL 1315
Score = 89.7 bits (221), Expect = 2e-17
Identities = 108/458 (23%), Positives = 180/458 (39%), Gaps = 62/458 (13%)
Query: 1239 CPSPV-----LNTPWIPFQNC--CYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRD 1291
CP P +T W N CY F N + + E H+ CQ +LSI D
Sbjct: 219 CPDPTSAEVGCDTIWEKDLNSHICYQF----NLLSSLSWSEAHSSCQMQG--GTLLSITD 272
Query: 1292 EKENNFVLEQLLYFNYMASWVMLGITYRNKSLMWFDKTPLSYTHWRAGRPTIKNEKFL-- 1349
E E NF+ E + + W+ L + W D TPL+Y +W P + E F+
Sbjct: 273 ETEENFIREHMSS-KTVEVWMGLNQLDEHAGWQWSDGTPLNYLNWS---PEVNFEPFVED 328
Query: 1350 -AGLSTDGFWDIQTFKVIEEAV-YFHQHSILACKIEMVD---YKEEYNTTLPQFMPYEDG 1404
G + + E + Y + + E+V+ +K P + PY
Sbjct: 329 HCGTFSSFMPSAWRSRDCESTLPYICKKYLNHIDHEIVEKDAWKYYATHCEPGWNPYNRN 388
Query: 1405 IYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLEDIV-KRDGFPLWVGLSSHDGSE 1463
Y + +++ TW+EAL C L + + FL ++ + W+GLSS+
Sbjct: 389 CYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASETWIGLSSNK-IP 447
Query: 1464 SSFEWSDGSTFDYIPW---KGQTSPGN---CVLLD-PKGTWKHEKCNSVKDGAICYKPTK 1516
SFEWS+ S+ + W + P CV + +G WK + C + IC K
Sbjct: 448 VSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEE-RLFYICKK--- 503
Query: 1517 SKKLSRLTYSSRCPAAKENGSR--WIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVS 1574
+ + E+G + W ++ G CYK D L SF +A S + +V+
Sbjct: 504 ---------AGHVLSDAESGCQEGWERHGGFCYKIDTVLRSFDQAS---SGYYCPPALVT 551
Query: 1575 IKDEDENKFVSRLMRENNNITMR---VWLGLSQHSVDQSWSWLDGSE----VTFVKWENK 1627
I + E F++ L+ ++ + M+ W+ L + ++W + V + W
Sbjct: 552 ITNRFEQAFITSLI--SSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTH 609
Query: 1628 SKSGVGRCSMLIASNE--TWKKVECEHGFGRVVCKVPL 1663
G C + + W+ C H +CK P+
Sbjct: 610 QPRYSGGCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPV 647
>gi|110624774 mannose receptor, C type 2 [Homo sapiens]
Length = 1479
Score = 746 bits (1927), Expect = 0.0
Identities = 456/1328 (34%), Positives = 670/1328 (50%), Gaps = 108/1328 (8%)
Query: 67 WKWVSQHRLFHLHSQKCLGLDI--TKSVNELRMFSCDSSAM-LWWKC-----EHHSLYGA 118
WKWVS++RLF+L + +CLG T + L M+ CD A+ L W C + L GA
Sbjct: 77 WKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLRWHCRTLGDQLSLLLGA 136
Query: 119 ARYRLALKDGHGTAISNASDVWKKGGSEESLCDQPYHEIYTRDGNSYGRPCEFPFLIDGT 178
++ S W+ GSEE LC PYHE+YT GNS+G+PC PF D
Sbjct: 137 RTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQGNSHGKPCTIPFKYDNQ 196
Query: 179 WHHDCILDEDHSGP-WCATTLNYEYDRKWGICLKPENGCEDNWEKNEQFGSCYQFNTQTA 237
W H C G WCATT +Y D +WG C N CE W+K++ SCYQFN Q+
Sbjct: 197 WFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQST 256
Query: 238 LSWKEAYVSCQNQGADLLSINSAAELTYLKE-KEGIAKIFWIGLNQLYSARGWEWSDHKP 296
LSW+EA+ SC+ QGADLLSI E TY+ G + WIGLN L ++ GW+WSD+ P
Sbjct: 257 LSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSP 316
Query: 297 LNFLNWDPDRPSAPTIGGSSCARMDAESGLWQSFSCEAQLPYVCRKPLNNTVELT--DVW 354
L +LNW+ D+P P+ R ++ SG WQ+ C LPYVC+K N T E T D W
Sbjct: 317 LKYLNWESDQPDNPSEENCGVIRTES-SGGWQNRDCSIALPYVCKKKPNATAEPTPPDRW 375
Query: 355 TYSDTRCDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHN 414
C+ W P G CY L E SW ++ C DL+SIHS+A++E + ++
Sbjct: 376 ANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQ 435
Query: 415 EDIKEEVWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYLGELGQWKV 474
E EE+WIGL ++ + F+WSDG+ V+ T+W EPN + +CV+ G G+W
Sbjct: 436 E--VEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEGRWND 493
Query: 475 QSCEEKLKYVCKRKGEKLNDASSDKMCPPDEGWKRHGETCYKIYEDEVPFGTNCNL---- 530
C + L +CK+ G+ L+ ++++ +GW H +CY + ED+V + L
Sbjct: 494 SPCNQSLPSICKKAGQ-LSQGAAEEDHGCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDH 552
Query: 531 -----TITSRFEQEYLNDLMKKYDKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSN 585
TIT+RFEQ +++ L+ ++ +YFWT L+D++S G + W + V +++
Sbjct: 553 GSQLVTITNRFEQAFVSSLIYNWE---GEYFWTALQDLNSTGSFFWLS----GDEVMYTH 605
Query: 586 WNFLEPA-SPGGCVAMSTGKSVGKWEVKDCRSFKALSICKKMSG-PLGPEEASPKP---- 639
WN +P S GGCVA++TG ++G WEVK+C SF+A IC++ G P+ PE P P
Sbjct: 606 WNRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPDPTPSL 665
Query: 640 DDPCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLH 699
CP+GW S CYKVF +ER+ K++W +A+ CQ LGA L S + +E + F+
Sbjct: 666 TGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEE-EHFVA 724
Query: 700 FLTDQFSG--------QHWLWIGLNKRSPDLQGSWQWSDRTPVSTIIMPNEFQQDYDIRD 751
+ ++ G QHW WIGLN+R P SW+WSD S D DIR
Sbjct: 725 NMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG 784
Query: 752 CAAVKVFHRPWRRGWHFYDDREFIYLRPFACDTKLEWVCQIPKGRTPKTPDWYNPDRAGI 811
CA + + W CDT+L+W+C+IP+G + PD D
Sbjct: 785 CAVLDLASLQW---------------VAMQCDTQLDWICKIPRGTDVREPD----DSPQG 825
Query: 812 HGPPLIIEGSEYWFVADLHLNYEEAVLYCASNHSFLATITSFVGLKAIKNKIANIS-GDG 870
L + +EY F + H + +A C + L ++ S L + + + S
Sbjct: 826 RREWLRFQEAEYKFF-EHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQE 884
Query: 871 QKWWIRISEWPIDDHFTY---------SRYPWHRFPVTFGEECLYMSAKTWLIDLGKPTD 921
Q WWI + D F + S P PV ++C+YM+A D G
Sbjct: 885 QHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPVGKDKKCVYMTASR--EDWGDQR- 941
Query: 922 CSTKLPFICEKYNVSSLEKYSPD--SAAKVQCSEQWIPFQNKCF--LKIKPVS-LTFSQA 976
C T LP+IC++ NV+ E PD + A C WI F NKCF +P S + +S+A
Sbjct: 942 CLTALPYICKRSNVTK-ETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEA 1000
Query: 977 SDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATLWIGLRWTAYEKINKWTDNRELTYSNF 1036
+C L ++ + +EQ FIT+ LP++ LWIGL A ++ +W + L Y+N+
Sbjct: 1001 QFSCEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLH--ASQRDFQWVEQEPLMYANW 1058
Query: 1037 HPLLVSGRLRIPENFFEEESRYHCALILNLQKSPFTGTWNFTSCSERHFVSLCQKYSEVK 1096
P SG P CA++L+ + FTG W+ SC+E +CQK ++
Sbjct: 1059 APGEPSGPSPAPSG----NKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPS 1114
Query: 1097 ---SRQTLQNASET-VKYLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITDPYQQAFLSV 1152
S L A T + YLN ++++ K L WH A C N L + DPY QAFL+
Sbjct: 1115 LSPSPAALPPAPGTELSYLNGTFRLLQKPLRWHDALLLCESRNASLAYVPDPYTQAFLTQ 1174
Query: 1153 QALLHNSSLWIGLFSQDDELNFGWSDGKRLHFSRWAETNGQLE-DCVVLDTDGFWKTVDC 1211
A + LWIGL ++ + W + L++ W + Q C +D DG W+T C
Sbjct: 1175 AARGLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSC 1234
Query: 1212 NDNQPGAIC-YYSGNETEKEVKPVDSVKCPSPVLNTPWIPFQNCCYNFIITKNRHMATTQ 1270
+ GA+C SG + + S CP + ++ WIPF+ CY+F + +
Sbjct: 1235 DTKLQGAVCGVSSGPPPPRRISYHGS--CPQGLADSAWIPFREHCYSF----HMELLLGH 1288
Query: 1271 DEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNYMASWVMLGITYRNK--SLMWFDK 1328
E +CQ+ +LSI DE EN FV E L + + LG+ + K +L+W D
Sbjct: 1289 KEARQRCQRAG--GAVLSILDEMENVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDN 1346
Query: 1329 TPLSYTHW 1336
T ++Y++W
Sbjct: 1347 TAVNYSNW 1354
Score = 256 bits (654), Expect = 1e-67
Identities = 297/1283 (23%), Positives = 499/1283 (38%), Gaps = 206/1283 (16%)
Query: 530 LTITSRFEQEYLNDLMKKYDKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFL 589
L+IT EQ Y+N L+ Y +L W GL D+D+ G + W+ + + NW
Sbjct: 274 LSITEIHEQTYINGLLTGYSSTL----WIGLNDLDTSGGWQWSD----NSPLKYLNWESD 325
Query: 590 EPASPG--GCVAMSTGKSVGKWEVKDCRSFKALSICKKMSGPLGPEEASPKPDD------ 641
+P +P C + T +S G W+ +DC S +CKK A P P D
Sbjct: 326 QPDNPSEENCGVIRT-ESSGGWQNRDC-SIALPYVCKKKPNAT----AEPTPPDRWANVK 379
Query: 642 -PCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHF 700
C WQ F CY++ AE KR+W+E+++ C G L S + E L F
Sbjct: 380 VECEPSWQPFQGH--CYRL-QAE----KRSWQESKKACLRGGGDLVSIHSMAE----LEF 428
Query: 701 LTDQFSGQ-HWLWIGLNKRSPDLQGSWQWSDRTPVSTI----IMPNEFQQDYDIRDCAAV 755
+T Q + LWIGLN LQ +++WSD + VS PN F+ + DC +
Sbjct: 429 ITKQIKQEVEELWIGLNDLK--LQMNFEWSDGSLVSFTHWHPFEPNNFRDS--LEDCVTI 484
Query: 756 KVFHRPWRRGWHFYDDREFIYLRPFACDTKLEWVC----QIPKGRTP------KTPDWYN 805
W + D C+ L +C Q+ +G K W++
Sbjct: 485 ------WGPEGRWNDS---------PCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHS 529
Query: 806 PDRAGIHGPPLIIEGSEYWFVADLHLNYEEAVLYCASNHSFLATITSFVGLKAIKNKIAN 865
P S YW D + Y EA C + S L TIT+ + + I N
Sbjct: 530 P--------------SCYWLGED-QVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYN 574
Query: 866 ISGDGQKWWIRISE--------WPIDDHFTYSRYPWHRFPVTFGEECLYMSAKTWLIDLG 917
+G+ +W + + W D Y+ W+R + A + L
Sbjct: 575 --WEGEYFWTALQDLNSTGSFFWLSGDEVMYTH--WNRDQPGYSRGGCVALATGSAMGLW 630
Query: 918 KPTDCST-KLPFICEKYNVSSL--EKYSPDSAAKV--QCSEQWIPFQNK--CFLKIKPVS 970
+ +C++ + +IC + + + E PD + C + W C+
Sbjct: 631 EVKNCTSFRARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWASDTKLRYCYKVFSSER 690
Query: 971 L----TFSQASDTCHSYGGTLPSVLSQIEQDFITSLL--------PDMEAT--LWIGL-- 1014
L ++ QA C G L S+ S E+ F+ ++L P++ WIGL
Sbjct: 691 LQDKKSWVQAQGACQELGAQLLSLASYEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNR 750
Query: 1015 RWTAYEKINKWTDNRELTYSNFHPLLVSGRLRIPENFFEEESRYHCALI--LNLQKSPFT 1072
R + +W+D +Y NF + +++ CA++ +LQ
Sbjct: 751 RDPRGGQSWRWSDGVGFSYHNFD-----------RSRHDDDDIRGCAVLDLASLQ----- 794
Query: 1073 GTWNFTSC-SERHFVSLCQKYSEVKSRQ-TLQNASETVKYLNNLYKIIPKTLTWHSAKRE 1130
W C ++ ++ + ++V+ + Q E +++ YK TW A+R
Sbjct: 795 --WVAMQCDTQLDWICKIPRGTDVREPDDSPQGRREWLRFQEAEYKFFEHHSTWAQAQRI 852
Query: 1131 CLKSNMQLVSITDPYQQAFLSVQ----ALLHNSSLWIGLFSQDDELNFGWSDGKRLHFSR 1186
C +L S+ + FLS + WIGL + + + F W+DG ++F
Sbjct: 853 CTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRFRWTDGSIINFIS 912
Query: 1187 WAETN----GQLEDCVVLDTDGF-WKTVDCNDNQPGAICYYSGNETEKEVKPVDSVKCPS 1241
WA G+ + CV + W C P IC S KE +P D
Sbjct: 913 WAPGKPRPVGKDKKCVYMTASREDWGDQRCLTALP-YICKRSN--VTKETQPPDLPTTAL 969
Query: 1242 PVLNTPWIPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQ 1301
+ WI F N C+ + + E C++ ++ +++I + E F+
Sbjct: 970 GGCPSDWIQFLNKCFQ-VQGQEPQSRVKWSEAQFSCEQ--QEAQLVTITNPLEQAFITAS 1026
Query: 1302 LLYFNYMASWVMLGITYRNKSLMWFDKTPLSYTHWRAGRPTIKNEKFLAGLSTD------ 1355
L + W+ G+ + W ++ PL Y +W G P+ + T
Sbjct: 1027 LPNVTFDL-WI--GLHASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLH 1083
Query: 1356 -------GFWDIQTFKVIEEAVYFHQHSILACKIEMVDYKEEYNTTLPQF----MPYEDG 1404
G WD ++ EE F C+ LP + Y +G
Sbjct: 1084 SPSAHFTGRWDDRS--CTEETHGF------ICQKGTDPSLSPSPAALPPAPGTELSYLNG 1135
Query: 1405 IYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHDGSES 1464
+ ++QK + W++AL +C LA V + Q FL + PLW+GL+ +GS
Sbjct: 1136 TFRLLQKPLRWHDALLLCESRNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSR- 1194
Query: 1465 SFEWSDGSTFDYIPWKG--QTSPGNCVLLDPKGTWKHEKCNSVKDGAICYKPTKSKKLSR 1522
+ W +Y+ W+ PG C +D G W+ C++ GA+C + R
Sbjct: 1195 RYSWVSEEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRR 1254
Query: 1523 LTYSSRCPAAKENGSRWIQYKGHCYKSD-QALHSFSEAKKLCSKHDHSATIVSIKDEDEN 1581
++Y CP + S WI ++ HCY + L EA++ C + ++SI DE EN
Sbjct: 1255 ISYHGSCPQGLAD-SAWIPFREHCYSFHMELLLGHKEARQRCQR--AGGAVLSILDEMEN 1311
Query: 1582 KFVSRLMRENNNITMRVWLGLSQHSVDQSWSWLDGSEVTFVKWE----NKSKSGVGRCSM 1637
FV ++ + WLG++ + + W D + V + W S C
Sbjct: 1312 VFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYW 1371
Query: 1638 LIASNETWKKVECEHGFGRVVCKVPLG----------PDYTA--IAIIVATLSILVLMGG 1685
+ +++ W+ C + VVCK+P P+ A + +++A L +L L+
Sbjct: 1372 IQSNSGLWRPGACTNITMGVVCKLPRAEQSSFSPSALPENPAALVVVLMAVLLLLALLTA 1431
Query: 1686 LIWFLFQRHRLHLAGFSSVRYAQ 1708
+ +R + F RY++
Sbjct: 1432 ALILYRRRQSIERGAFEGARYSR 1454
Score = 172 bits (437), Expect = 2e-42
Identities = 235/1106 (21%), Positives = 410/1106 (37%), Gaps = 162/1106 (14%)
Query: 637 PKPDDPCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKE 696
P + C W + SCY+ + +W EA C+ GA L S + + E +
Sbjct: 229 PIKSNDCETFWDKDQLTDSCYQFNFQSTL----SWREAWASCEQQGADLLSITEIHE-QT 283
Query: 697 FLHFLTDQFSGQHWLWIGLNKRSPDLQGSWQWSDRTPVSTIIMPNEFQQDYDIRDCAAVK 756
+++ L +S LWIGLN D G WQWSD +P+ + ++ + +C ++
Sbjct: 284 YINGLLTGYSST--LWIGLNDL--DTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIR 339
Query: 757 VFHRPWRRGWHFYDDREFIYLRPFACDTKLEWVCQIPKGRT--PKTPDWYNPDRAGIHGP 814
GW D C L +VC+ T P PD + +
Sbjct: 340 TESSG---GWQNRD-----------CSIALPYVCKKKPNATAEPTPPDRWANVKVECEPS 385
Query: 815 PLIIEGSEYWFVADLHLNYEEAVLYCASNHSFLATITSFVGLKAIKNKIANISGDGQKWW 874
+G Y A+ +++E+ C L +I S L+ I +I + ++ W
Sbjct: 386 WQPFQGHCYRLQAEKR-SWQESKKACLRGGGDLVSIHSMAELEFITKQIKQ---EVEELW 441
Query: 875 IRISEWPIDDHFTYSRYP------WHRFPVTFGEECLYMSAKTWLIDLGKPTD--CSTKL 926
I +++ + +F +S WH F + L W + G+ D C+ L
Sbjct: 442 IGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPE-GRWNDSPCNQSL 500
Query: 927 PFICEKYNVSSLEKYSPDSAAKVQCSEQWIPFQNKCFLKIKPVSLTFSQASDTCHSYGGT 986
P IC+K S D C + W C+ + +T+S+A C +G
Sbjct: 501 PSICKKAGQLSQGAAEEDHG----CRKGWTWHSPSCYW-LGEDQVTYSEARRLCTDHGSQ 555
Query: 987 LPSVLSQIEQDFITSLLPDMEATLWIGLRWTAYEKINK-----WTDNRELTYSNFHPLLV 1041
L ++ ++ EQ F++SL+ + E + WTA + +N W E+ Y++++
Sbjct: 556 LVTITNRFEQAFVSSLIYNWEGEYF----WTALQDLNSTGSFFWLSGDEVMYTHWN---- 607
Query: 1042 SGRLRIPENFFEEESRYHCALILNLQKSPFTGTWNFTSCSERHFVSLCQKYSEVKSRQTL 1101
++ Y + L G W +C+ +C++ L
Sbjct: 608 -----------RDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPEL 656
Query: 1102 QNASETVKY-------------LNNLYKI-----IPKTLTWHSAKRECLKSNMQLVSITD 1143
T L YK+ + +W A+ C + QL+S+
Sbjct: 657 PGPDPTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLAS 716
Query: 1144 PYQQAFLS---------VQALLHNSS-LWIGLFSQDDE--LNFGWSDGKRL---HFSRWA 1188
++ F++ + +H WIGL +D ++ WSDG +F R
Sbjct: 717 YEEEHFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSR 776
Query: 1189 ETNGQLEDCVVLDTDGF-WKTVDCNDNQPGAICYYSGNETEKEVKPVDSVKCPSPVLNTP 1247
+ + C VLD W + C D Q IC +E P DS P
Sbjct: 777 HDDDDIRGCAVLDLASLQWVAMQC-DTQLDWICKIPRGTDVRE--PDDS-----PQGRRE 828
Query: 1248 WIPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNY 1307
W+ FQ Y F H +T + C ++ + S+ + E +F+ L F+
Sbjct: 829 WLRFQEAEYKFF---EHH--STWAQAQRICTWF--QAELTSVHSQAELDFLSHNLQKFSR 881
Query: 1308 MAS---WVMLGITYRNKSLMWFDKTPLSYTHWRAG--RPTIKNEKFLAGLSTDGFWDIQT 1362
W+ L + + W D + +++ W G RP K++K + ++ W Q
Sbjct: 882 AQEQHWWIGLHTSESDGRFRWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDWGDQ- 940
Query: 1363 FKVIEEAVYFHQHSILACKIEMVDYKEEYNTTLPQ-FMPYEDGIYSVI----QKKVTWYE 1417
+ + Y + S + + + D P ++ + + + V Q +V W E
Sbjct: 941 -RCLTALPYICKRSNVTKETQPPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSE 999
Query: 1418 ALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHDGSESSFEWSDGSTFDYI 1477
A C Q L ++ N Q F+ + F LW+GL + S+ F+W + Y
Sbjct: 1000 AQFSCEQQEAQLVTITNPLEQAFITASLPNVTFDLWIGLHA---SQRDFQWVEQEPLMYA 1056
Query: 1478 PW-KGQTS----------PGNC--VLLDPK----GTWKHEKCNSVKDGAICYKPTKSKKL 1520
W G+ S P +C VL P G W C G IC K T
Sbjct: 1057 NWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPS-- 1114
Query: 1521 SRLTYSSRCPAAKENG-SRWIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDED 1579
S PAA + Y ++ Q + +A LC +A++ + D
Sbjct: 1115 -----LSPSPAALPPAPGTELSYLNGTFRLLQKPLRWHDALLLC--ESRNASLAYVPDPY 1167
Query: 1580 ENKFVSRLMRENNNITMRVWLGLSQHSVDQSWSWLDGSEVTFVKWENKSKSGVGRCSMLI 1639
F+++ R + +W+GL+ + +SW+ + +V W++ G C+ +
Sbjct: 1168 TQAFLTQAAR---GLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEPQQPGGCT-YV 1223
Query: 1640 ASNETWKKVECEHGFGRVVCKVPLGP 1665
+ W+ C+ VC V GP
Sbjct: 1224 DVDGAWRTTSCDTKLQGAVCGVSSGP 1249
Score = 123 bits (309), Expect = 1e-27
Identities = 107/429 (24%), Positives = 182/429 (42%), Gaps = 38/429 (8%)
Query: 1255 CYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNYMASWVML 1314
CY F N + E C++ + +LSI + E ++ L ++ W+ L
Sbjct: 248 CYQF----NFQSTLSWREAWASCEQQG--ADLLSITEIHEQTYINGLLTGYS-STLWIGL 300
Query: 1315 GITYRNKSLMWFDKTPLSYTHWRAGRPTIKNEKFLAGLSTD--GFWDIQTFKVIEEAVYF 1372
+ W D +PL Y +W + +P +E+ + T+ G W + + V
Sbjct: 301 NDLDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCK 360
Query: 1373 HQHSILACKIEMVDYKEEYNTTLPQFMPYEDGIYSVIQKKVTWYEALNMCSQSGGHLASV 1432
+ + A + P + P++ Y + +K +W E+ C + GG L S+
Sbjct: 361 KKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSI 420
Query: 1433 HNQNGQLFLEDIVKRDGFPLWVGLSSHDGSESSFEWSDGSTFDYIPW------KGQTSPG 1486
H+ F+ +K++ LW+GL+ + +FEWSDGS + W + S
Sbjct: 421 HSMAELEFITKQIKQEVEELWIGLNDLK-LQMNFEWSDGSLVSFTHWHPFEPNNFRDSLE 479
Query: 1487 NCVLL-DPKGTWKHEKCNSVKDGAICYKPTKSKKLSRLTYSSRCPAAKENGSR--WIQYK 1543
+CV + P+G W CN P+ KK +L S+ A +++G R W +
Sbjct: 480 DCVTIWGPEGRWNDSPCNQ-------SLPSICKKAGQL---SQGAAEEDHGCRKGWTWHS 529
Query: 1544 GHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRVWLGLS 1603
CY + ++SEA++LC+ DH + +V+I + E FVS L+ N W L
Sbjct: 530 PSCYWLGEDQVTYSEARRLCT--DHGSQLVTITNRFEQAFVSSLI--YNWEGEYFWTALQ 585
Query: 1604 QHSVDQSWSWLDGSEVTFVKWENKSKSGVGR--CSMLIASNE--TWKKVECEHGFGRVVC 1659
+ S+ WL G EV + W N+ + G R C L + W+ C R +C
Sbjct: 586 DLNSTGSFFWLSGDEVMYTHW-NRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYIC 644
Query: 1660 KVPLGPDYT 1668
+ LG T
Sbjct: 645 RQSLGTPVT 653
Score = 63.2 bits (152), Expect = 2e-09
Identities = 36/120 (30%), Positives = 56/120 (46%), Gaps = 5/120 (4%)
Query: 229 CYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTY----LKEKEGIAKIFWIGLNQLY 284
CY F+ + L KEA CQ G +LSI E + L+ EG ++ W+G+N
Sbjct: 1277 CYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQSYEGQSRGAWLGMNFNP 1336
Query: 285 SARGWEWSDHKPLNFLNWDPDRPSAPTIGGSSCARMDAESGLWQSFSC-EAQLPYVCRKP 343
W D+ +N+ NW P + +SC + + SGLW+ +C + VC+ P
Sbjct: 1337 KGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWRPGACTNITMGVVCKLP 1396
>gi|57546917 mannose receptor, C type 1-like 1 [Homo sapiens]
Length = 1456
Score = 536 bits (1381), Expect = e-152
Identities = 391/1359 (28%), Positives = 617/1359 (45%), Gaps = 129/1359 (9%)
Query: 61 ETEDKLWKWVSQHRLFHLHSQKCLGLDITKSVNELRMFSCDS-SAMLWWKCEHHSLYGAA 119
+ E + ++WVS+ ++ + + CLG+ + +++CDS S W+C++ +L G
Sbjct: 52 DAESQKFRWVSESQIMSVAFKLCLGVPSKTDWVAITLYACDSKSEFQKWECKNDTLLGIK 111
Query: 120 RYRLALKDGH----GTAISNASDVWKKG---GSEESLCDQPYHEIYTRDGNSYGRPCEFP 172
L G+ + S +W + G+ ++LC + Y +YT GN+ G C FP
Sbjct: 112 GEDLFFNYGNRQEKNIMLYKGSGLWSRWKIYGTTDNLCSRGYEAMYTLLGNANGATCAFP 171
Query: 173 FLIDGTWHHDCILDEDHSG-PWCATTLNYEYDRKWGICLKPENGCEDNWEKNEQFGSCYQ 231
F + W+ DC G WC TT +Y+ D+ +G C G E W K+ YQ
Sbjct: 172 FKFENKWYADCTSAGRSDGWLWCGTTTDYDTDKLFGYCPLKFEGSESLWNKDPLTSVSYQ 231
Query: 232 FNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKE-KEGIAKIFWIGLNQLYSARGWE 290
N+++AL+W +A SCQ Q A+LLSI E TYL + WIGLN L GW+
Sbjct: 232 INSKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQ 291
Query: 291 WSDHKPLNFLNWDPDRPSAPTIGGSSCARMD-AESGLWQSFSCEAQLPYVCRKPLNNTVE 349
WSD P +LNW P PSA G SC ++ ++ W++ C +L Y+C+K N T+
Sbjct: 292 WSDRSPFRYLNWLPGSPSAEP--GKSCVSLNPGKNAKWENLECVQKLGYICKKG-NTTLN 348
Query: 350 LTDVWTYSD--TRCDAGWLPNNGFCYLLVNESNSWDK-AHAKCKAFSSDLISIHSLADVE 406
+ + SD T C + W P G CY + + + A C+ SDL SIH++ + +
Sbjct: 349 SFVIPSESDVPTHCPSQWWPYAGHCYKIHRDEKKIQRDALTTCRKEGSDLASIHTIEEFD 408
Query: 407 VVVTKLHNEDIKEEVWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYL 466
++++L E +E+WIGL +I I F+WSDGT VT T W EP+ N+ +CV
Sbjct: 409 FIISQLGYEP-NDELWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMK 467
Query: 467 GELGQWKVQSCEEKLKYVCKRKGEKLNDASSDKMCPPDEGWKRHGETCYKIYEDEVPF-- 524
G+ G W + CE L Y+CK K + +GWK+H CY I F
Sbjct: 468 GKDGYWADRGCEWPLGYICKMKSRSQGPEIVEVEKGCRKGWKKHHFYCYMIGHTLSTFAE 527
Query: 525 -GTNCN------LTITSRFEQEYLNDLMKKYDKSLRKYFWTGLRDVDSCGEYNWATVGGR 577
CN TI R+EQ +L + + KYFWTGL D+ + G + W
Sbjct: 528 ANQTCNNENAYLTTIEDRYEQAFLTSFVGLRPE---KYFWTGLSDIQTKGTFQWTI---- 580
Query: 578 RRAVTFSNWNFLEPASPGGCVAMSTGKSVGKWEVKDCRSFKALSICKKMS-GPLGPEEAS 636
V F++WN P GCVAM TG + G W+V C KA +CK + G P + +
Sbjct: 581 EEEVRFTHWNSDMPGRKPGCVAMRTGIAGGLWDVLKCDE-KAKFVCKHWAEGVTHPPKPT 639
Query: 637 PKPDDPCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKE 696
P+ CPE W + + C+K++ A+ K+ W E+ FC+ALG L+S ++ +E +
Sbjct: 640 TTPEPKCPEDWGASSRTSLCFKLY-AKGKHEKKTWFESRDFCRALGGDLASINNKEEQQT 698
Query: 697 FLHFLTDQFSGQHWLWIGLNKRSPDLQGSWQWSDRTPVS----TIIMPNEFQQDYDIRDC 752
+T S W+GL SP + WSD +PVS PN +Q ++ C
Sbjct: 699 IWRLITASGSYHKLFWLGLTYGSP--SEGFTWSDGSPVSYENWAYGEPNNYQ---NVEYC 753
Query: 753 AAVKVFHRPWRRGWHFYDDREFIYLRPFACDTKLEWVCQIPKGRTPKTPDWYNPDRAGIH 812
+K W+ C+ W+CQI KG+TPK P A
Sbjct: 754 GELK---GDPTMSWN-----------DINCEHLNNWICQIQKGQTPKP----EPTPAPQD 795
Query: 813 GPPLIIEG------SEYWFVADLHLNYEEAVLYCASNHSFLATITSFVGLKAIKNKIANI 866
PP+ +G +Y+F + + A +C N L +I S K + +
Sbjct: 796 NPPVTEDGWVIYKDYQYYFSKEKE-TMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNR- 853
Query: 867 SGDGQKWWIRISEWPIDDHFTY------SRYPWHRFPVTFGEE-----CLYMSAKTWLID 915
D Q + +D F + W F E +Y ++ W
Sbjct: 854 -NDAQSAYFIGLLISLDKKFAWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGFW--- 909
Query: 916 LGKPTDCSTKLPFICEKYN--VSSLEKYSPDSAAKVQCSEQWIPFQNKCFL---KIKPVS 970
+C FIC+++N +++ + C E W + NKCF ++
Sbjct: 910 --NDINCGYPNAFICQRHNSSINATTVMPTMPSVPSGCKEGWNFYSNKCFKIFGFMEEER 967
Query: 971 LTFSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATLWIGLRWTAYEKINKWTDNRE 1030
+ +A C +GG L S+ ++ EQ F+T + D + W GL E WTD R
Sbjct: 968 KNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVNSEHTFLWTDGRG 1027
Query: 1031 LTYSNFHPLLVSGRLRIPENFFEEESRYHCALILNLQKSPFTGTWNFTSC-SERHFVSLC 1089
+ Y+N+ GR R ++ + + C +I+ S G W +C S+R ++ C
Sbjct: 1028 VHYTNWGKGYPGGR-RSSLSYEDAD----CVVIIG-GASNEAGKWMDDTCDSKRGYI--C 1079
Query: 1090 QKYSEVKSRQTLQNASET------VKYLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITD 1143
Q +S +L N T VKY + Y ++ + WH A+ C N + SI D
Sbjct: 1080 Q----TRSDPSLTNPPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKLHNSLIASILD 1135
Query: 1144 PYQQAFLSVQALLHNSSLWIGLFSQDDELNFGWSDGKRLHFSRWAETNGQLED-CVVLDT 1202
PY AF +Q N +WI L S + + W+D R+ ++ WA +L+ CV LD
Sbjct: 1136 PYSNAFAWLQMETSNERVWIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKSACVYLDL 1195
Query: 1203 DGFWKTVDCNDNQPGAICYYSGNETEKEVKPVDSVKCPSPVLNTPWIPFQNCCYNFIITK 1262
DG+WKT CN++ +C S +E P +CP +T WIPF CY +
Sbjct: 1196 DGYWKTAHCNESF-YFLCKRS-DEIPATEPPQLPGRCPESD-HTAWIPFHGHCYYIESSY 1252
Query: 1263 NRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNYMAS-WVMLGITYRN- 1320
R+ + +C ++ S ++SI E++F+ ++ + W+ L +RN
Sbjct: 1253 TRNWG----QASLECLRMG--SSLVSIESAAESSFLSYRVEPLKSKTNFWIGL---FRNV 1303
Query: 1321 -KSLMWFDKTPLSYTHWRAGRPTIKNEKFLAGLSTDGFW 1358
+ +W + +P+S+ +W G P+ + +A ++ GFW
Sbjct: 1304 EGTWLWINNSPVSFVNWNTGDPSGERNDCVALHASSGFW 1342
Score = 227 bits (578), Expect = 9e-59
Identities = 288/1248 (23%), Positives = 489/1248 (39%), Gaps = 163/1248 (13%)
Query: 530 LTITSRFEQEYLNDLMKKYDKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFL 589
L+IT EQ YL L SL W GL + + W+ R + NW
Sbjct: 255 LSITEIHEQTYLTGLTS----SLTSGLWIGLNSLSFNSGWQWSD----RSPFRYLNWLPG 306
Query: 590 EP-ASPG-GCVAMSTGKSVGKWEVKDCRSFKALSICKKMSGPLGPEEASPKPDDP--CPE 645
P A PG CV+++ GK+ KWE +C K ICKK + L + D P CP
Sbjct: 307 SPSAEPGKSCVSLNPGKNA-KWENLECVQ-KLGYICKKGNTTLNSFVIPSESDVPTHCPS 364
Query: 646 GWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFLTDQF 705
W +P + CYK+ E+ +++ +A C+ G+ L+S ++E + L +
Sbjct: 365 QW--WPYAGHCYKIHRDEKKIQR----DALTTCRKEGSDLASIHTIEEFDFIISQLGYEP 418
Query: 706 SGQHWLWIGLNKRSPDLQGSWQWSDRTPVSTI--IMPNEFQQDYDIRDCAAVKVFHRPWR 763
+ + LWIGLN +Q ++WSD TPV+ + ++ DC +K W
Sbjct: 419 NDE--LWIGLNDIK--IQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGKDGYWA 474
Query: 764 RGWHFYDDREFIYLRPFACDTKLEWVCQIP-KGRTPKTPDWYNPDRAGIHGPPLIIEGSE 822
DR C+ L ++C++ + + P+ + R G
Sbjct: 475 -------DR--------GCEWPLGYICKMKSRSQGPEIVEVEKGCRKGWKKHHFYC---- 515
Query: 823 YWFVADLHLNYEEAVLYCASNHSFLATI---------TSFVGLKAIKNKIANISGDGQKW 873
+ + + EA C + +++L TI TSFVGL+ K +S K
Sbjct: 516 -YMIGHTLSTFAEANQTCNNENAYLTTIEDRYEQAFLTSFVGLRPEKYFWTGLSDIQTKG 574
Query: 874 WIRISEWPIDDHFTYSRYPWHRFPVTFGEECLYMSAKTWLID-LGKPTDCSTKLPFICEK 932
+W I++ ++ W+ C+ M +T + L C K F+C+
Sbjct: 575 TF---QWTIEEEVRFTH--WNSDMPGRKPGCVAM--RTGIAGGLWDVLKCDEKAKFVCKH 627
Query: 933 YNVSSLEKYSPDSAAKVQCSEQWIPFQN-----KCFLKIKPVSLTFSQASDTCHSYGGTL 987
+ P + + +C E W K + K K T+ ++ D C + GG L
Sbjct: 628 WAEGVTHPPKPTTTPEPKCPEDWGASSRTSLCFKLYAKGKHEKKTWFESRDFCRALGGDL 687
Query: 988 PSVLSQIEQDFITSLLP---DMEATLWIGLRWTAYEKINKWTDNRELTYSNFHPLLVSGR 1044
S+ ++ EQ I L+ W+GL + + + W+D ++Y N+
Sbjct: 688 ASINNKEEQQTIWRLITASGSYHKLFWLGLTYGSPSEGFTWSDGSPVSYENWA------- 740
Query: 1045 LRIPENFFEEESRYHCALILNLQKSPFTGTWNFTSCSE-RHFVSLCQKYSEVKSRQT--- 1100
+ E + Y K T +WN +C +++ QK K T
Sbjct: 741 -------YGEPNNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQIQKGQTPKPEPTPAP 793
Query: 1101 LQNASET----VKYLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITDPYQQAFL--SVQA 1154
N T V Y + Y + T +A+ C ++ LVSI ++ FL V
Sbjct: 794 QDNPPVTEDGWVIYKDYQYYFSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNR 853
Query: 1155 LLHNSSLWIGLFSQDDELNFGWSDGKRLHFSRWA--ETNGQLED--CVVL-DTDGFWKTV 1209
S+ +IGL D+ F W DG ++ + WA E N ED CV + GFW +
Sbjct: 854 NDAQSAYFIGLLISLDK-KFAWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGFWNDI 912
Query: 1210 DCNDNQPGAICYYSGNETEKEVKPVDSVKCPSPVLNTPWIPFQNCCYNFIITKNRHMATT 1269
+C P A N + + ++ W + N C+
Sbjct: 913 NCG--YPNAFICQRHNSSINATTVMPTMPSVPSGCKEGWNFYSNKCFKIFGFMEEERKNW 970
Query: 1270 QDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNYMASWVMLGITYRNKSLMWFDKT 1329
Q E C + +++SI++EKE F+ + + A W L + +W D
Sbjct: 971 Q-EARKAC--IGFGGNLVSIQNEKEQAFLTYHMKDSTFSA-WTGLNDVNSEHTFLWTDGR 1026
Query: 1330 PLSYTHWRAGRPTIKNEKFLAGLSTDGFWDIQTFKVI----EEAVYFHQHSILACKIEMV 1385
+ YT+W G P + S+ + D +I EA + + + + +
Sbjct: 1027 GVHYTNWGKGYPGGRR-------SSLSYEDADCVVIIGGASNEAGKWMDDTCDSKRGYIC 1079
Query: 1386 DYKEEYNTTLPQ-------FMPYEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQ 1438
+ + + T P F+ Y YS++++K W+EA C +AS+ +
Sbjct: 1080 QTRSDPSLTNPPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKLHNSLIASILDPYSN 1139
Query: 1439 LFLEDIVKRDGFPLWVGLSSHDGSESSFEWSDGSTFDYIPWKGQTSP--GNCVLLDPKGT 1496
F ++ +W+ L+S+ +++ + W+D Y W CV LD G
Sbjct: 1140 AFAWLQMETSNERVWIALNSNL-TDNQYTWTDKWRVRYTNWAADEPKLKSACVYLDLDGY 1198
Query: 1497 WKHEKCNSVKDGAICYKPTKSKKLSRLTYSSRCPAAKENGSRWIQYKGHCYKSDQAL-HS 1555
WK CN +C + + RCP + + + WI + GHCY + + +
Sbjct: 1199 WKTAHCNE-SFYFLCKRSDEIPATEPPQLPGRCP--ESDHTAWIPFHGHCYYIESSYTRN 1255
Query: 1556 FSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRVWLGLSQHSVDQSWSWLD 1615
+ +A C + S +VSI+ E+ F+S + + T W+GL ++ V+ +W W++
Sbjct: 1256 WGQASLECLRMGSS--LVSIESAAESSFLSYRVEPLKSKT-NFWIGLFRN-VEGTWLWIN 1311
Query: 1616 GSEVTFVKWENKSKSGV-GRCSMLIASNETWKKVECEHGFGRVVCKVP------------ 1662
S V+FV W SG C L AS+ W + C + +CK P
Sbjct: 1312 NSPVSFVNWNTGDPSGERNDCVALHASSGFWSNIHCS-SYKGYICKRPKIIDAKPTHELL 1370
Query: 1663 --------LGP----DYTAIAIIVATLSILVLMGGLIWFLFQRHRLHL 1698
+ P A +I+ L IL G +F +++ R+HL
Sbjct: 1371 TTKADTRKMDPSKPSSNVAGVVIIVILLILTGAGLAAYFFYKKRRVHL 1418
Score = 182 bits (461), Expect = 3e-45
Identities = 254/1091 (23%), Positives = 423/1091 (38%), Gaps = 185/1091 (16%)
Query: 647 WQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFLTDQFS 706
W P + Y++ + W +A + CQ A L S + + E + +L LT +
Sbjct: 220 WNKDPLTSVSYQINSKSALT----WHQARKSCQQQNAELLSITEIHE-QTYLTGLTSSLT 274
Query: 707 GQHWLWIGLNKRSPDLQGSWQWSDRTPVSTIIMPNEFQQDYDIRDCAAVKVFHRPWRRG- 765
LWIGLN S WQWSDR+P + + C ++ P +
Sbjct: 275 SG--LWIGLNSLS--FNSGWQWSDRSPFRYLNWLPGSPSAEPGKSCVSLN----PGKNAK 326
Query: 766 WHFYDDREFIYLRPFACDTKLEWVCQIPKGRTPKTPDWYNPDRAGI--HGPPLIIEGSEY 823
W + C KL ++C+ KG T + P + + H P S++
Sbjct: 327 WENLE-----------CVQKLGYICK--KGNTTLN-SFVIPSESDVPTHCP------SQW 366
Query: 824 WFVAD----LHLNYE----EAVLYCASNHSFLATITSFVGLKAIKNKIANISGDGQKWWI 875
W A +H + + +A+ C S LA+I + I +++ D + WI
Sbjct: 367 WPYAGHCYKIHRDEKKIQRDALTTCRKEGSDLASIHTIEEFDFIISQLGYEPND--ELWI 424
Query: 876 RISEWPIDDHFTYSRYPWHRFPVTFG--------------EECLYMSAKT-WLIDLGKPT 920
+++ I +F +S PVTF E+C+ M K + D G
Sbjct: 425 GLNDIKIQMYFEWS----DGTPVTFTKWLRGEPSHENNRQEDCVVMKGKDGYWADRG--- 477
Query: 921 DCSTKLPFICEKYNVSSLEKYSPDSA-AKVQCSEQWIPFQNKCFLKIKPVSLTFSQASDT 979
C L +IC+ + S P+ + C + W C++ +S TF++A+ T
Sbjct: 478 -CEWPLGYICKMKSRSQ----GPEIVEVEKGCRKGWKKHHFYCYMIGHTLS-TFAEANQT 531
Query: 980 CHSYGGTLPSVLSQIEQDFITSLLP-DMEATLWIGLRWTAYEKINKWTDNRELTYSNFHP 1038
C++ L ++ + EQ F+TS + E W GL + +WT E+ +++++
Sbjct: 532 CNNENAYLTTIEDRYEQAFLTSFVGLRPEKYFWTGLSDIQTKGTFQWTIEEEVRFTHWNS 591
Query: 1039 LLVSGRLRIPENFFEEESRYHCALILNLQKSPFTGTWNFTSCSER-HFVSLCQKYSE--- 1094
+ GR + C ++ G W+ C E+ FV C+ ++E
Sbjct: 592 DM-PGR------------KPGCVA---MRTGIAGGLWDVLKCDEKAKFV--CKHWAEGVT 633
Query: 1095 --VKSRQTLQ-------NASETVKYLNNLY-KIIPKTLTWHSAKRECLKSNMQLVSITDP 1144
K T + AS LY K + TW ++ C L SI +
Sbjct: 634 HPPKPTTTPEPKCPEDWGASSRTSLCFKLYAKGKHEKKTWFESRDFCRALGGDLASINNK 693
Query: 1145 YQQAF---LSVQALLHNSSLWIGLFSQDDELNFGWSDGKRLHFSRWA--ETNG--QLEDC 1197
+Q L + ++ W+GL F WSDG + + WA E N +E C
Sbjct: 694 EEQQTIWRLITASGSYHKLFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYC 753
Query: 1198 VVLDTDGF--WKTVDCNDNQPGAICYYSGNETEKEVKPVDSVKCPSPVLNTPWIPFQNCC 1255
L D W ++C ++ IC +T K +P + + PV W+ +++
Sbjct: 754 GELKGDPTMSWNDINC-EHLNNWICQIQKGQTPKP-EPTPAPQDNPPVTEDGWVIYKD-- 809
Query: 1256 YNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNYMASWVMLG 1315
Y + +K + T D C++ ++SI+ E E F+ + + + +++ +
Sbjct: 810 YQYYFSKEKE---TMDNARAFCKR--NFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGL 864
Query: 1316 ITYRNKSLMWFDKTPLSYTHWRAGRPTIKNE--KFLAGLSTDGFW-DIQTFKVIEEAVYF 1372
+ +K W D + + Y W G P NE + S GFW DI
Sbjct: 865 LISLDKKFAWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGFWNDINCGYPNAFICQR 924
Query: 1373 HQHSILACKIEMV------DYKEEYNTTLPQFMPYEDGIYSVI----QKKVTWYEALNMC 1422
H SI A + KE +N Y + + + +++ W EA C
Sbjct: 925 HNSSINATTVMPTMPSVPSGCKEGWNF-------YSNKCFKIFGFMEEERKNWQEARKAC 977
Query: 1423 SQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHDGSESSFEWSDGSTFDYIPWKGQ 1482
GG+L S+ N+ Q FL +K F W GL+ + SE +F W+DG Y W G+
Sbjct: 978 IGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVN-SEHTFLWTDGRGVHYTNW-GK 1035
Query: 1483 TSPG-----------NCVLL-----DPKGTWKHEKCNSVKDGAICYKPTKSKKLSRLTYS 1526
PG +CV++ + G W + C+S K G IC +R S
Sbjct: 1036 GYPGGRRSSLSYEDADCVVIIGGASNEAGKWMDDTCDS-KRGYICQ--------TRSDPS 1086
Query: 1527 SRCPAAKENGSRWIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSR 1586
P A +++Y Y + + EA+ C H++ I SI D N F
Sbjct: 1087 LTNPPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKL--HNSLIASILDPYSNAFAWL 1144
Query: 1587 LMRENNNITMRVWLGLSQHSVDQSWSWLDGSEVTFVKW---ENKSKSGVGRCSMLIASNE 1643
M +N RVW+ L+ + D ++W D V + W E K KS + + +
Sbjct: 1145 QMETSNE---RVWIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKS----ACVYLDLDG 1197
Query: 1644 TWKKVECEHGF 1654
WK C F
Sbjct: 1198 YWKTAHCNESF 1208
Score = 142 bits (358), Expect = 3e-33
Identities = 132/595 (22%), Positives = 237/595 (39%), Gaps = 57/595 (9%)
Query: 217 EDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKE---KEGIA 273
ED W + + + +T A C+ DL+SI S +E +L + +
Sbjct: 801 EDGWVIYKDYQYYFSKEKETM---DNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQ 857
Query: 274 KIFWIGLNQLYSARGWEWSDHKPLNFLNWDPDRPSAPTIGGSSCARMDAESGLWQSFSCE 333
++IGL + + + W D +++++W P+ +C M + SG W +C
Sbjct: 858 SAYFIGL-LISLDKKFAWMDGSKVDYVSWATGEPNFAN-EDENCVTMYSNSGFWNDINCG 915
Query: 334 AQLPYVCRKPLNNTVELTDVWTYSDT---RCDAGWLPNNGFCY----LLVNESNSWDKAH 386
++C++ N+++ T V + C GW + C+ + E +W +A
Sbjct: 916 YPNAFICQRH-NSSINATTVMPTMPSVPSGCKEGWNFYSNKCFKIFGFMEEERKNWQEAR 974
Query: 387 AKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEEVWIGLKNINIPTLFQWSDGTEVTLTY 446
C F +L+SI + + E H +D W GL ++N F W+DG V T
Sbjct: 975 KACIGFGGNLVSIQN--EKEQAFLTYHMKDSTFSAWTGLNDVNSEHTFLWTDGRGVHYTN 1032
Query: 447 WDENEP-----NVPYNKTPNCVSYLG----ELGQWKVQSCEEKLKYVCKRKGEKLNDASS 497
W + P ++ Y +CV +G E G+W +C+ K Y+C+ + + ++
Sbjct: 1033 WGKGYPGGRRSSLSYEDA-DCVVIIGGASNEAGKWMDDTCDSKRGYICQTRSDP--SLTN 1089
Query: 498 DKMCPPDEGWKRHGETCYKIYEDEVPFG---TNCNL--TITSRFEQEYLNDLMKKYDKSL 552
+G+ ++G++ Y + + + T C L ++ + Y N ++
Sbjct: 1090 PPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKLHNSLIASILDPYSNAFAWLQMETS 1149
Query: 553 RKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFLEPASPGGCVAMSTGKSVGKWEVK 612
+ W L + +Y W + V ++NW EP CV + G W+
Sbjct: 1150 NERVWIALNSNLTDNQYTWTD----KWRVRYTNWAADEPKLKSACVYLDLD---GYWKTA 1202
Query: 613 DCRSFKALSICKKMSGPLGPEEASPKPDDPCPEGWQS--FPASLSCYKVFHAERIVRKRN 670
C +CK+ P P+ CPE + P CY + + RN
Sbjct: 1203 HCNE-SFYFLCKRSDEI--PATEPPQLPGRCPESDHTAWIPFHGHCYYIESSYT----RN 1255
Query: 671 WEEAERFCQALGAHLSSFSHVDEIKEFLHFLTDQFSGQHWLWIGLNKRSPDLQGSWQWSD 730
W +A C +G+ L S E FL + + + WIGL + +++G+W W +
Sbjct: 1256 WGQASLECLRMGSSLVSIESAAE-SSFLSYRVEPLKSKTNFWIGLFR---NVEGTWLWIN 1311
Query: 731 RTPVSTIIMPNEFQQDYDIRDCAAVKVFHRPWRRGWHFYDDREFIYLRPFACDTK 785
+PVS + N + DC A+ W H + +I RP D K
Sbjct: 1312 NSPVS-FVNWNTGDPSGERNDCVALHASSGFW-SNIHCSSYKGYICKRPKIIDAK 1364
Score = 114 bits (285), Expect = 8e-25
Identities = 113/447 (25%), Positives = 177/447 (39%), Gaps = 67/447 (14%)
Query: 214 NGCEDNWEKNEQFGSCYQ---FNTQTALSWKEAYVSCQNQGADLLSINSAAE---LTYLK 267
+GC++ W N C++ F + +W+EA +C G +L+SI + E LTY
Sbjct: 943 SGCKEGW--NFYSNKCFKIFGFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHM 1000
Query: 268 EKEGIAKIFWIGLNQLYSARGWEWSDHKPLNFLNWDPDRPSAPT-------------IGG 314
+ + W GLN + S + W+D + +++ NW P IGG
Sbjct: 1001 KDSTFSA--WTGLNDVNSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGG 1058
Query: 315 SSCARMDAESGLWQSFSCEAQLPYVCRKPLNNTVELTDVWTYSDTRCDAGWLPNNGFCYL 374
+S E+G W +C+++ Y+C+ + ++ +D G++ Y
Sbjct: 1059 AS-----NEAGKWMDDTCDSKRGYICQTRSDPSLTNPPATIQTD-----GFVKYGKSSYS 1108
Query: 375 LVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEEVWIGLKNINIPTLF 434
L+ + W +A CK +S + SI L L E E VWI L + +
Sbjct: 1109 LMRQKFQWHEAETYCKLHNSLIASI--LDPYSNAFAWLQMETSNERVWIALNSNLTDNQY 1166
Query: 435 QWSDGTEVTLTYWDENEPNVPYNKTPNCVSYLGELGQWKVQSCEEKLKYVCKRKGE--KL 492
W+D V T W +EP K + YL G WK C E ++CKR E
Sbjct: 1167 TWTDKWRVRYTNWAADEP-----KLKSACVYLDLDGYWKTAHCNESFYFLCKRSDEIPAT 1221
Query: 493 NDASSDKMCPPDE--GWKRHGETCYKIYEDEVPFGTNCNL----------TITSRFEQEY 540
CP + W CY I +L +I S E +
Sbjct: 1222 EPPQLPGRCPESDHTAWIPFHGHCYYIESSYTRNWGQASLECLRMGSSLVSIESAAESSF 1281
Query: 541 LNDLMKKYDKSLRKYFWTGL-RDVDSCGEYNWATVGGRRRAVTFSNWNFLEPASP-GGCV 598
L+ ++ + FW GL R+V+ G + W V+F NWN +P+ CV
Sbjct: 1282 LSYRVEPLKS--KTNFWIGLFRNVE--GTWLWI----NNSPVSFVNWNTGDPSGERNDCV 1333
Query: 599 AMSTGKSVGKWEVKDCRSFKALSICKK 625
A+ S G W C S+K ICK+
Sbjct: 1334 ALHA--SSGFWSNIHCSSYKGY-ICKR 1357
Score = 94.7 bits (234), Expect = 7e-19
Identities = 76/260 (29%), Positives = 113/260 (43%), Gaps = 20/260 (7%)
Query: 1413 VTWYEALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHDGSESSFEWSDGS 1472
+TW++A C Q L S+ + Q +L + LW+GL+S + S ++WSD S
Sbjct: 238 LTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFN-SGWQWSDRS 296
Query: 1473 TFDYIPW---KGQTSPG-NCVLLDPKGTWKHEKCNSV-KDGAICYKPTKSKKLSRLTYSS 1527
F Y+ W PG +CV L+P K E V K G IC K + L+ S
Sbjct: 297 PFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLECVQKLGYICKKGNTT--LNSFVIPS 354
Query: 1528 RCPAAKENGSRWIQYKGHCYKSDQALHSFS-EAKKLCSKHDHSATIVSIKDEDENKFV-S 1585
S+W Y GHCYK + +A C K + + SI +E F+ S
Sbjct: 355 ESDVPTHCPSQWWPYAGHCYKIHRDEKKIQRDALTTCRKE--GSDLASIHTIEEFDFIIS 412
Query: 1586 RLMRENNNITMRVWLGLSQHSVDQSWSWLDGSEVTFVKWENKSKSGVGR----CSMLIAS 1641
+L E N+ +W+GL+ + + W DG+ VTF KW S C ++
Sbjct: 413 QLGYEPND---ELWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGK 469
Query: 1642 NETWKKVECEHGFGRVVCKV 1661
+ W CE G +CK+
Sbjct: 470 DGYWADRGCEWPLG-YICKM 488
>gi|4505245 mannose receptor C type 1 precursor [Homo sapiens]
Length = 1456
Score = 535 bits (1379), Expect = e-151
Identities = 390/1359 (28%), Positives = 617/1359 (45%), Gaps = 129/1359 (9%)
Query: 61 ETEDKLWKWVSQHRLFHLHSQKCLGLDITKSVNELRMFSCDS-SAMLWWKCEHHSLYGAA 119
+ E + ++WVS+ ++ + + CLG+ + +++CDS S W+C++ +L G
Sbjct: 52 DAESQKFRWVSESQIMSVAFKLCLGVPSKTDWVAITLYACDSKSEFQKWECKNDTLLGIK 111
Query: 120 RYRLALKDGH----GTAISNASDVWKKG---GSEESLCDQPYHEIYTRDGNSYGRPCEFP 172
L G+ + S +W + G+ ++LC + Y +YT GN+ G C FP
Sbjct: 112 GEDLFFNYGNRQEKNIMLYKGSGLWSRWKIYGTTDNLCSRGYEAMYTLLGNANGATCAFP 171
Query: 173 FLIDGTWHHDCILDEDHSG-PWCATTLNYEYDRKWGICLKPENGCEDNWEKNEQFGSCYQ 231
F + W+ DC G WC TT +Y+ D+ +G C G E W K+ YQ
Sbjct: 172 FKFENKWYADCTSAGRSDGWLWCGTTTDYDTDKLFGYCPLKFEGSESLWNKDPLTSVSYQ 231
Query: 232 FNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKE-KEGIAKIFWIGLNQLYSARGWE 290
N+++AL+W +A SCQ Q A+LLSI E TYL + WIGLN L GW+
Sbjct: 232 INSKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQ 291
Query: 291 WSDHKPLNFLNWDPDRPSAPTIGGSSCARMD-AESGLWQSFSCEAQLPYVCRKPLNNTVE 349
WSD P +LNW P PSA G SC ++ ++ W++ C +L Y+C+K N T+
Sbjct: 292 WSDRSPFRYLNWLPGSPSAEP--GKSCVSLNPGKNAKWENLECVQKLGYICKKG-NTTLN 348
Query: 350 LTDVWTYSD--TRCDAGWLPNNGFCYLLVNESNSWDK-AHAKCKAFSSDLISIHSLADVE 406
+ + SD T C + W P G CY + + + A C+ DL SIH++ +++
Sbjct: 349 SFVIPSESDVPTHCPSQWWPYAGHCYKIHRDEKKIQRDALTTCRKEGGDLTSIHTIEELD 408
Query: 407 VVVTKLHNEDIKEEVWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYL 466
++++L E +E+WIGL +I I F+WSDGT VT T W EP+ N+ +CV
Sbjct: 409 FIISQLGYEP-NDELWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMK 467
Query: 467 GELGQWKVQSCEEKLKYVCKRKGEKLNDASSDKMCPPDEGWKRHGETCYKIYEDEVPF-- 524
G+ G W + CE L Y+CK K + +GWK+H CY I F
Sbjct: 468 GKDGYWADRGCEWPLGYICKMKSRSQGPEIVEVEKGCRKGWKKHHFYCYMIGHTLSTFAE 527
Query: 525 -GTNCN------LTITSRFEQEYLNDLMKKYDKSLRKYFWTGLRDVDSCGEYNWATVGGR 577
CN TI R+EQ +L + + KYFWTGL D+ + G + W
Sbjct: 528 ANQTCNNENAYLTTIEDRYEQAFLTSFVGLRPE---KYFWTGLSDIQTKGTFQWTI---- 580
Query: 578 RRAVTFSNWNFLEPASPGGCVAMSTGKSVGKWEVKDCRSFKALSICKKMS-GPLGPEEAS 636
V F++WN P GCVAM TG + G W+V C KA +CK + G P + +
Sbjct: 581 EEEVRFTHWNSDMPGRKPGCVAMRTGIAGGLWDVLKCDE-KAKFVCKHWAEGVTHPPKPT 639
Query: 637 PKPDDPCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKE 696
P+ CPE W + + C+K++ A+ K+ W E+ FC+ALG L+S ++ +E +
Sbjct: 640 TTPEPKCPEDWGASSRTSLCFKLY-AKGKHEKKTWFESRDFCRALGGDLASINNKEEQQT 698
Query: 697 FLHFLTDQFSGQHWLWIGLNKRSPDLQGSWQWSDRTPVS----TIIMPNEFQQDYDIRDC 752
+T S W+GL SP + WSD +PVS PN +Q ++ C
Sbjct: 699 IWRLITASGSYHKLFWLGLTYGSP--SEGFTWSDGSPVSYENWAYGEPNNYQ---NVEYC 753
Query: 753 AAVKVFHRPWRRGWHFYDDREFIYLRPFACDTKLEWVCQIPKGRTPKTPDWYNPDRAGIH 812
+K W+ C+ W+CQI KG+TPK P A
Sbjct: 754 GELK---GDPTMSWN-----------DINCEHLNNWICQIQKGQTPKP----EPTPAPQD 795
Query: 813 GPPLIIEG------SEYWFVADLHLNYEEAVLYCASNHSFLATITSFVGLKAIKNKIANI 866
PP+ +G +Y+F + + A +C N L +I S K + +
Sbjct: 796 NPPVTEDGWVIYKDYQYYFSKEKE-TMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNR- 853
Query: 867 SGDGQKWWIRISEWPIDDHFTY------SRYPWHRFPVTFGEE-----CLYMSAKTWLID 915
D Q + +D F + W F E +Y ++ W
Sbjct: 854 -NDAQSAYFIGLLISLDKKFAWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGFW--- 909
Query: 916 LGKPTDCSTKLPFICEKYN--VSSLEKYSPDSAAKVQCSEQWIPFQNKCFL---KIKPVS 970
+C FIC+++N +++ + C E W + NKCF ++
Sbjct: 910 --NDINCGYPNAFICQRHNSSINATTVMPTMPSVPSGCKEGWNFYSNKCFKIFGFMEEER 967
Query: 971 LTFSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATLWIGLRWTAYEKINKWTDNRE 1030
+ +A C +GG L S+ ++ EQ F+T + D + W GL E WTD R
Sbjct: 968 KNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVNSEHTFLWTDGRG 1027
Query: 1031 LTYSNFHPLLVSGRLRIPENFFEEESRYHCALILNLQKSPFTGTWNFTSC-SERHFVSLC 1089
+ Y+N+ GR R ++ + + C +I+ S G W +C S+R ++ C
Sbjct: 1028 VHYTNWGKGYPGGR-RSSLSYEDAD----CVVIIG-GASNEAGKWMDDTCDSKRGYI--C 1079
Query: 1090 QKYSEVKSRQTLQNASET------VKYLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITD 1143
Q +S +L N T VKY + Y ++ + WH A+ C N + SI D
Sbjct: 1080 Q----TRSDPSLTNPPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKLHNSLIASILD 1135
Query: 1144 PYQQAFLSVQALLHNSSLWIGLFSQDDELNFGWSDGKRLHFSRWAETNGQLED-CVVLDT 1202
PY AF +Q N +WI L S + + W+D R+ ++ WA +L+ CV LD
Sbjct: 1136 PYSNAFAWLQMETSNERVWIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKSACVYLDL 1195
Query: 1203 DGFWKTVDCNDNQPGAICYYSGNETEKEVKPVDSVKCPSPVLNTPWIPFQNCCYNFIITK 1262
DG+WKT CN++ +C S +E P +CP +T WIPF CY +
Sbjct: 1196 DGYWKTAHCNESF-YFLCKRS-DEIPATEPPQLPGRCPESD-HTAWIPFHGHCYYIESSY 1252
Query: 1263 NRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNYMAS-WVMLGITYRN- 1320
R+ + +C ++ S ++SI E++F+ ++ + W+ L +RN
Sbjct: 1253 TRNWG----QASLECLRMG--SSLVSIESAAESSFLSYRVEPLKSKTNFWIGL---FRNV 1303
Query: 1321 -KSLMWFDKTPLSYTHWRAGRPTIKNEKFLAGLSTDGFW 1358
+ +W + +P+S+ +W G P+ + +A ++ GFW
Sbjct: 1304 EGTWLWINNSPVSFVNWNTGDPSGERNDCVALHASSGFW 1342
Score = 228 bits (581), Expect = 4e-59
Identities = 290/1250 (23%), Positives = 488/1250 (39%), Gaps = 167/1250 (13%)
Query: 530 LTITSRFEQEYLNDLMKKYDKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFL 589
L+IT EQ YL L SL W GL + + W+ R + NW
Sbjct: 255 LSITEIHEQTYLTGLTS----SLTSGLWIGLNSLSFNSGWQWSD----RSPFRYLNWLPG 306
Query: 590 EP-ASPG-GCVAMSTGKSVGKWEVKDCRSFKALSICKKMSGPLGPEEASPKPDDP--CPE 645
P A PG CV+++ GK+ KWE +C K ICKK + L + D P CP
Sbjct: 307 SPSAEPGKSCVSLNPGKNA-KWENLECVQ-KLGYICKKGNTTLNSFVIPSESDVPTHCPS 364
Query: 646 GWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFLTDQ- 704
W +P + CYK+ E+ +++ +A C+ G L+S ++E L F+ Q
Sbjct: 365 QW--WPYAGHCYKIHRDEKKIQR----DALTTCRKEGGDLTSIHTIEE----LDFIISQL 414
Query: 705 -FSGQHWLWIGLNKRSPDLQGSWQWSDRTPVSTI--IMPNEFQQDYDIRDCAAVKVFHRP 761
+ LWIGLN +Q ++WSD TPV+ + ++ DC +K
Sbjct: 415 GYEPNDELWIGLNDIK--IQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGKDGY 472
Query: 762 WRRGWHFYDDREFIYLRPFACDTKLEWVCQIP-KGRTPKTPDWYNPDRAGIHGPPLIIEG 820
W DR C+ L ++C++ + + P+ + R G
Sbjct: 473 WA-------DR--------GCEWPLGYICKMKSRSQGPEIVEVEKGCRKGWKKHHFYC-- 515
Query: 821 SEYWFVADLHLNYEEAVLYCASNHSFLATI---------TSFVGLKAIKNKIANISGDGQ 871
+ + + EA C + +++L TI TSFVGL+ K +S
Sbjct: 516 ---YMIGHTLSTFAEANQTCNNENAYLTTIEDRYEQAFLTSFVGLRPEKYFWTGLSDIQT 572
Query: 872 KWWIRISEWPIDDHFTYSRYPWHRFPVTFGEECLYMSAKTWLID-LGKPTDCSTKLPFIC 930
K +W I++ ++ W+ C+ M +T + L C K F+C
Sbjct: 573 KGTF---QWTIEEEVRFTH--WNSDMPGRKPGCVAM--RTGIAGGLWDVLKCDEKAKFVC 625
Query: 931 EKYNVSSLEKYSPDSAAKVQCSEQWIPFQN-----KCFLKIKPVSLTFSQASDTCHSYGG 985
+ + P + + +C E W K + K K T+ ++ D C + GG
Sbjct: 626 KHWAEGVTHPPKPTTTPEPKCPEDWGASSRTSLCFKLYAKGKHEKKTWFESRDFCRALGG 685
Query: 986 TLPSVLSQIEQDFITSLLP---DMEATLWIGLRWTAYEKINKWTDNRELTYSNFHPLLVS 1042
L S+ ++ EQ I L+ W+GL + + + W+D ++Y N+
Sbjct: 686 DLASINNKEEQQTIWRLITASGSYHKLFWLGLTYGSPSEGFTWSDGSPVSYENWA----- 740
Query: 1043 GRLRIPENFFEEESRYHCALILNLQKSPFTGTWNFTSCSE-RHFVSLCQKYSEVKSRQT- 1100
+ E + Y K T +WN +C +++ QK K T
Sbjct: 741 ---------YGEPNNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQIQKGQTPKPEPTP 791
Query: 1101 --LQNASET----VKYLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITDPYQQAFL--SV 1152
N T V Y + Y + T +A+ C ++ LVSI ++ FL V
Sbjct: 792 APQDNPPVTEDGWVIYKDYQYYFSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYV 851
Query: 1153 QALLHNSSLWIGLFSQDDELNFGWSDGKRLHFSRWA--ETNGQLED--CVVL-DTDGFWK 1207
S+ +IGL D+ F W DG ++ + WA E N ED CV + GFW
Sbjct: 852 NRNDAQSAYFIGLLISLDK-KFAWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGFWN 910
Query: 1208 TVDCNDNQPGAICYYSGNETEKEVKPVDSVKCPSPVLNTPWIPFQNCCYNFIITKNRHMA 1267
++C P A N + + ++ W + N C+
Sbjct: 911 DINCG--YPNAFICQRHNSSINATTVMPTMPSVPSGCKEGWNFYSNKCFKIFGFMEEERK 968
Query: 1268 TTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNYMASWVMLGITYRNKSLMWFD 1327
Q E C + +++SI++EKE F+ + + A W L + +W D
Sbjct: 969 NWQ-EARKAC--IGFGGNLVSIQNEKEQAFLTYHMKDSTFSA-WTGLNDVNSEHTFLWTD 1024
Query: 1328 KTPLSYTHWRAGRPTIKNEKFLAGLSTDGFWDIQTFKVI----EEAVYFHQHSILACKIE 1383
+ YT+W G P + S+ + D +I EA + + + +
Sbjct: 1025 GRGVHYTNWGKGYPGGRR-------SSLSYEDADCVVIIGGASNEAGKWMDDTCDSKRGY 1077
Query: 1384 MVDYKEEYNTTLPQ-------FMPYEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQN 1436
+ + + + T P F+ Y YS++++K W+EA C +AS+ +
Sbjct: 1078 ICQTRSDPSLTNPPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKLHNSLIASILDPY 1137
Query: 1437 GQLFLEDIVKRDGFPLWVGLSSHDGSESSFEWSDGSTFDYIPWKGQTSP--GNCVLLDPK 1494
F ++ +W+ L+S+ +++ + W+D Y W CV LD
Sbjct: 1138 SNAFAWLQMETSNERVWIALNSNL-TDNQYTWTDKWRVRYTNWAADEPKLKSACVYLDLD 1196
Query: 1495 GTWKHEKCNSVKDGAICYKPTKSKKLSRLTYSSRCPAAKENGSRWIQYKGHCYKSDQAL- 1553
G WK CN +C + + RCP + + + WI + GHCY + +
Sbjct: 1197 GYWKTAHCNE-SFYFLCKRSDEIPATEPPQLPGRCP--ESDHTAWIPFHGHCYYIESSYT 1253
Query: 1554 HSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRVWLGLSQHSVDQSWSW 1613
++ +A C + S +VSI+ E+ F+S + + T W+GL ++ V+ +W W
Sbjct: 1254 RNWGQASLECLRMGSS--LVSIESAAESSFLSYRVEPLKSKT-NFWIGLFRN-VEGTWLW 1309
Query: 1614 LDGSEVTFVKWENKSKSGV-GRCSMLIASNETWKKVECEHGFGRVVCKVP---------- 1662
++ S V+FV W SG C L AS+ W + C + +CK P
Sbjct: 1310 INNSPVSFVNWNTGDPSGERNDCVALHASSGFWSNIHCS-SYKGYICKRPKIIDAKPTHE 1368
Query: 1663 ----------LGP----DYTAIAIIVATLSILVLMGGLIWFLFQRHRLHL 1698
+ P A +I+ L IL G +F +++ R+HL
Sbjct: 1369 LLTTKADTRKMDPSKPSSNVAGVVIIVILLILTGAGLAAYFFYKKRRVHL 1418
Score = 180 bits (457), Expect = 9e-45
Identities = 253/1091 (23%), Positives = 422/1091 (38%), Gaps = 185/1091 (16%)
Query: 647 WQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFLTDQFS 706
W P + Y++ + W +A + CQ A L S + + E + +L LT +
Sbjct: 220 WNKDPLTSVSYQINSKSALT----WHQARKSCQQQNAELLSITEIHE-QTYLTGLTSSLT 274
Query: 707 GQHWLWIGLNKRSPDLQGSWQWSDRTPVSTIIMPNEFQQDYDIRDCAAVKVFHRPWRRG- 765
LWIGLN S WQWSDR+P + + C ++ P +
Sbjct: 275 SG--LWIGLNSLS--FNSGWQWSDRSPFRYLNWLPGSPSAEPGKSCVSLN----PGKNAK 326
Query: 766 WHFYDDREFIYLRPFACDTKLEWVCQIPKGRTPKTPDWYNPDRAGI--HGPPLIIEGSEY 823
W + C KL ++C+ KG T + P + + H P S++
Sbjct: 327 WENLE-----------CVQKLGYICK--KGNTTLN-SFVIPSESDVPTHCP------SQW 366
Query: 824 WFVAD----LHLNYE----EAVLYCASNHSFLATITSFVGLKAIKNKIANISGDGQKWWI 875
W A +H + + +A+ C L +I + L I +++ D + WI
Sbjct: 367 WPYAGHCYKIHRDEKKIQRDALTTCRKEGGDLTSIHTIEELDFIISQLGYEPND--ELWI 424
Query: 876 RISEWPIDDHFTYSRYPWHRFPVTFG--------------EECLYMSAKT-WLIDLGKPT 920
+++ I +F +S PVTF E+C+ M K + D G
Sbjct: 425 GLNDIKIQMYFEWS----DGTPVTFTKWLRGEPSHENNRQEDCVVMKGKDGYWADRG--- 477
Query: 921 DCSTKLPFICEKYNVSSLEKYSPDSA-AKVQCSEQWIPFQNKCFLKIKPVSLTFSQASDT 979
C L +IC+ + S P+ + C + W C++ +S TF++A+ T
Sbjct: 478 -CEWPLGYICKMKSRSQ----GPEIVEVEKGCRKGWKKHHFYCYMIGHTLS-TFAEANQT 531
Query: 980 CHSYGGTLPSVLSQIEQDFITSLLP-DMEATLWIGLRWTAYEKINKWTDNRELTYSNFHP 1038
C++ L ++ + EQ F+TS + E W GL + +WT E+ +++++
Sbjct: 532 CNNENAYLTTIEDRYEQAFLTSFVGLRPEKYFWTGLSDIQTKGTFQWTIEEEVRFTHWNS 591
Query: 1039 LLVSGRLRIPENFFEEESRYHCALILNLQKSPFTGTWNFTSCSER-HFVSLCQKYSE--- 1094
+ GR + C ++ G W+ C E+ FV C+ ++E
Sbjct: 592 DM-PGR------------KPGCVA---MRTGIAGGLWDVLKCDEKAKFV--CKHWAEGVT 633
Query: 1095 --VKSRQTLQ-------NASETVKYLNNLY-KIIPKTLTWHSAKRECLKSNMQLVSITDP 1144
K T + AS LY K + TW ++ C L SI +
Sbjct: 634 HPPKPTTTPEPKCPEDWGASSRTSLCFKLYAKGKHEKKTWFESRDFCRALGGDLASINNK 693
Query: 1145 YQQAF---LSVQALLHNSSLWIGLFSQDDELNFGWSDGKRLHFSRWA--ETNG--QLEDC 1197
+Q L + ++ W+GL F WSDG + + WA E N +E C
Sbjct: 694 EEQQTIWRLITASGSYHKLFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYC 753
Query: 1198 VVLDTDGF--WKTVDCNDNQPGAICYYSGNETEKEVKPVDSVKCPSPVLNTPWIPFQNCC 1255
L D W ++C ++ IC +T K +P + + PV W+ +++
Sbjct: 754 GELKGDPTMSWNDINC-EHLNNWICQIQKGQTPKP-EPTPAPQDNPPVTEDGWVIYKD-- 809
Query: 1256 YNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNYMASWVMLG 1315
Y + +K + T D C++ ++SI+ E E F+ + + + +++ +
Sbjct: 810 YQYYFSKEKE---TMDNARAFCKR--NFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGL 864
Query: 1316 ITYRNKSLMWFDKTPLSYTHWRAGRPTIKNE--KFLAGLSTDGFW-DIQTFKVIEEAVYF 1372
+ +K W D + + Y W G P NE + S GFW DI
Sbjct: 865 LISLDKKFAWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGFWNDINCGYPNAFICQR 924
Query: 1373 HQHSILACKIEMV------DYKEEYNTTLPQFMPYEDGIYSVI----QKKVTWYEALNMC 1422
H SI A + KE +N Y + + + +++ W EA C
Sbjct: 925 HNSSINATTVMPTMPSVPSGCKEGWNF-------YSNKCFKIFGFMEEERKNWQEARKAC 977
Query: 1423 SQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHDGSESSFEWSDGSTFDYIPWKGQ 1482
GG+L S+ N+ Q FL +K F W GL+ + SE +F W+DG Y W G+
Sbjct: 978 IGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVN-SEHTFLWTDGRGVHYTNW-GK 1035
Query: 1483 TSPG-----------NCVLL-----DPKGTWKHEKCNSVKDGAICYKPTKSKKLSRLTYS 1526
PG +CV++ + G W + C+S K G IC +R S
Sbjct: 1036 GYPGGRRSSLSYEDADCVVIIGGASNEAGKWMDDTCDS-KRGYICQ--------TRSDPS 1086
Query: 1527 SRCPAAKENGSRWIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSR 1586
P A +++Y Y + + EA+ C H++ I SI D N F
Sbjct: 1087 LTNPPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKL--HNSLIASILDPYSNAFAWL 1144
Query: 1587 LMRENNNITMRVWLGLSQHSVDQSWSWLDGSEVTFVKW---ENKSKSGVGRCSMLIASNE 1643
M +N RVW+ L+ + D ++W D V + W E K KS + + +
Sbjct: 1145 QMETSNE---RVWIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKS----ACVYLDLDG 1197
Query: 1644 TWKKVECEHGF 1654
WK C F
Sbjct: 1198 YWKTAHCNESF 1208
Score = 142 bits (358), Expect = 3e-33
Identities = 132/595 (22%), Positives = 237/595 (39%), Gaps = 57/595 (9%)
Query: 217 EDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKE---KEGIA 273
ED W + + + +T A C+ DL+SI S +E +L + +
Sbjct: 801 EDGWVIYKDYQYYFSKEKETM---DNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQ 857
Query: 274 KIFWIGLNQLYSARGWEWSDHKPLNFLNWDPDRPSAPTIGGSSCARMDAESGLWQSFSCE 333
++IGL + + + W D +++++W P+ +C M + SG W +C
Sbjct: 858 SAYFIGL-LISLDKKFAWMDGSKVDYVSWATGEPNFAN-EDENCVTMYSNSGFWNDINCG 915
Query: 334 AQLPYVCRKPLNNTVELTDVWTYSDT---RCDAGWLPNNGFCY----LLVNESNSWDKAH 386
++C++ N+++ T V + C GW + C+ + E +W +A
Sbjct: 916 YPNAFICQRH-NSSINATTVMPTMPSVPSGCKEGWNFYSNKCFKIFGFMEEERKNWQEAR 974
Query: 387 AKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEEVWIGLKNINIPTLFQWSDGTEVTLTY 446
C F +L+SI + + E H +D W GL ++N F W+DG V T
Sbjct: 975 KACIGFGGNLVSIQN--EKEQAFLTYHMKDSTFSAWTGLNDVNSEHTFLWTDGRGVHYTN 1032
Query: 447 WDENEP-----NVPYNKTPNCVSYLG----ELGQWKVQSCEEKLKYVCKRKGEKLNDASS 497
W + P ++ Y +CV +G E G+W +C+ K Y+C+ + + ++
Sbjct: 1033 WGKGYPGGRRSSLSYEDA-DCVVIIGGASNEAGKWMDDTCDSKRGYICQTRSDP--SLTN 1089
Query: 498 DKMCPPDEGWKRHGETCYKIYEDEVPFG---TNCNL--TITSRFEQEYLNDLMKKYDKSL 552
+G+ ++G++ Y + + + T C L ++ + Y N ++
Sbjct: 1090 PPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKLHNSLIASILDPYSNAFAWLQMETS 1149
Query: 553 RKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFLEPASPGGCVAMSTGKSVGKWEVK 612
+ W L + +Y W + V ++NW EP CV + G W+
Sbjct: 1150 NERVWIALNSNLTDNQYTWTD----KWRVRYTNWAADEPKLKSACVYLDLD---GYWKTA 1202
Query: 613 DCRSFKALSICKKMSGPLGPEEASPKPDDPCPEGWQS--FPASLSCYKVFHAERIVRKRN 670
C +CK+ P P+ CPE + P CY + + RN
Sbjct: 1203 HCNE-SFYFLCKRSDEI--PATEPPQLPGRCPESDHTAWIPFHGHCYYIESSYT----RN 1255
Query: 671 WEEAERFCQALGAHLSSFSHVDEIKEFLHFLTDQFSGQHWLWIGLNKRSPDLQGSWQWSD 730
W +A C +G+ L S E FL + + + WIGL + +++G+W W +
Sbjct: 1256 WGQASLECLRMGSSLVSIESAAE-SSFLSYRVEPLKSKTNFWIGLFR---NVEGTWLWIN 1311
Query: 731 RTPVSTIIMPNEFQQDYDIRDCAAVKVFHRPWRRGWHFYDDREFIYLRPFACDTK 785
+PVS + N + DC A+ W H + +I RP D K
Sbjct: 1312 NSPVS-FVNWNTGDPSGERNDCVALHASSGFW-SNIHCSSYKGYICKRPKIIDAK 1364
Score = 114 bits (285), Expect = 8e-25
Identities = 113/447 (25%), Positives = 177/447 (39%), Gaps = 67/447 (14%)
Query: 214 NGCEDNWEKNEQFGSCYQ---FNTQTALSWKEAYVSCQNQGADLLSINSAAE---LTYLK 267
+GC++ W N C++ F + +W+EA +C G +L+SI + E LTY
Sbjct: 943 SGCKEGW--NFYSNKCFKIFGFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHM 1000
Query: 268 EKEGIAKIFWIGLNQLYSARGWEWSDHKPLNFLNWDPDRPSAPT-------------IGG 314
+ + W GLN + S + W+D + +++ NW P IGG
Sbjct: 1001 KDSTFSA--WTGLNDVNSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGG 1058
Query: 315 SSCARMDAESGLWQSFSCEAQLPYVCRKPLNNTVELTDVWTYSDTRCDAGWLPNNGFCYL 374
+S E+G W +C+++ Y+C+ + ++ +D G++ Y
Sbjct: 1059 AS-----NEAGKWMDDTCDSKRGYICQTRSDPSLTNPPATIQTD-----GFVKYGKSSYS 1108
Query: 375 LVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEEVWIGLKNINIPTLF 434
L+ + W +A CK +S + SI L L E E VWI L + +
Sbjct: 1109 LMRQKFQWHEAETYCKLHNSLIASI--LDPYSNAFAWLQMETSNERVWIALNSNLTDNQY 1166
Query: 435 QWSDGTEVTLTYWDENEPNVPYNKTPNCVSYLGELGQWKVQSCEEKLKYVCKRKGE--KL 492
W+D V T W +EP K + YL G WK C E ++CKR E
Sbjct: 1167 TWTDKWRVRYTNWAADEP-----KLKSACVYLDLDGYWKTAHCNESFYFLCKRSDEIPAT 1221
Query: 493 NDASSDKMCPPDE--GWKRHGETCYKIYEDEVPFGTNCNL----------TITSRFEQEY 540
CP + W CY I +L +I S E +
Sbjct: 1222 EPPQLPGRCPESDHTAWIPFHGHCYYIESSYTRNWGQASLECLRMGSSLVSIESAAESSF 1281
Query: 541 LNDLMKKYDKSLRKYFWTGL-RDVDSCGEYNWATVGGRRRAVTFSNWNFLEPASP-GGCV 598
L+ ++ + FW GL R+V+ G + W V+F NWN +P+ CV
Sbjct: 1282 LSYRVEPLKS--KTNFWIGLFRNVE--GTWLWI----NNSPVSFVNWNTGDPSGERNDCV 1333
Query: 599 AMSTGKSVGKWEVKDCRSFKALSICKK 625
A+ S G W C S+K ICK+
Sbjct: 1334 ALHA--SSGFWSNIHCSSYKGY-ICKR 1357
Score = 94.4 bits (233), Expect = 9e-19
Identities = 77/260 (29%), Positives = 112/260 (43%), Gaps = 20/260 (7%)
Query: 1413 VTWYEALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHDGSESSFEWSDGS 1472
+TW++A C Q L S+ + Q +L + LW+GL+S + S ++WSD S
Sbjct: 238 LTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFN-SGWQWSDRS 296
Query: 1473 TFDYIPW---KGQTSPG-NCVLLDPKGTWKHEKCNSV-KDGAICYKPTKSKKLSRLTYSS 1527
F Y+ W PG +CV L+P K E V K G IC K + L+ S
Sbjct: 297 PFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLECVQKLGYICKKGNTT--LNSFVIPS 354
Query: 1528 RCPAAKENGSRWIQYKGHCYKSDQALHSFS-EAKKLCSKHDHSATIVSIKDEDENKFV-S 1585
S+W Y GHCYK + +A C K T SI +E F+ S
Sbjct: 355 ESDVPTHCPSQWWPYAGHCYKIHRDEKKIQRDALTTCRKEGGDLT--SIHTIEELDFIIS 412
Query: 1586 RLMRENNNITMRVWLGLSQHSVDQSWSWLDGSEVTFVKWENKSKSGVGR----CSMLIAS 1641
+L E N+ +W+GL+ + + W DG+ VTF KW S C ++
Sbjct: 413 QLGYEPND---ELWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGK 469
Query: 1642 NETWKKVECEHGFGRVVCKV 1661
+ W CE G +CK+
Sbjct: 470 DGYWADRGCEWPLG-YICKM 488
>gi|26892293 CD302 molecule [Homo sapiens]
Length = 232
Score = 84.0 bits (206), Expect = 1e-15
Identities = 53/180 (29%), Positives = 90/180 (50%), Gaps = 21/180 (11%)
Query: 1529 CPAAKENGSRWIQYKGHCYKSDQA---LHSFSEAKKLCSKHDHSATIVSIKDEDENKFVS 1585
CP+ S WIQ++ CY Q + S + + C+ DH A ++SI +E+EN F+
Sbjct: 24 CPS-----STWIQFQDSCYIFLQEAIKVESIEDVRNQCT--DHGADMISIHNEEENAFIL 76
Query: 1586 RLMRENNNITMRVWLGLSQHSVDQSWSWLDGSEVTFVKW--ENKSKSGVGRCSMLIASNE 1643
+++ + LG+ + D S+ W D S +TF KW ++ + V C+ L
Sbjct: 77 DTLKKQWKGPDDILLGMFYDTDDASFKWFDNSNMTFDKWTDQDDDEDLVDTCAFLHIKTG 136
Query: 1644 TWKKVECE-HGFGRVVCK--VPLGPDYTA------IAIIVATLSILVLMGGLIWFLFQRH 1694
WKK CE +CK +P Y + A+++A+ IL ++G +IWFL+++H
Sbjct: 137 EWKKGNCEVSSVEGTLCKTAIPYKRKYLSDNHILISALVIASTVILTVLGAIIWFLYKKH 196
Score = 50.4 bits (119), Expect = 1e-05
Identities = 37/141 (26%), Positives = 60/141 (42%), Gaps = 21/141 (14%)
Query: 1398 FMPYEDGIYSVIQKKV---TWYEALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWV 1454
++ ++D Y +Q+ + + + N C+ G + S+HN+ F+ D +K+ W
Sbjct: 29 WIQFQDSCYIFLQEAIKVESIEDVRNQCTDHGADMISIHNEEENAFILDTLKKQ----WK 84
Query: 1455 GLSS------HDGSESSFEWSDGSTFDYIPWKGQTSP----GNCVLLDPK-GTWKHEKCN 1503
G +D ++SF+W D S + W Q C L K G WK C
Sbjct: 85 GPDDILLGMFYDTDDASFKWFDNSNMTFDKWTDQDDDEDLVDTCAFLHIKTGEWKKGNCE 144
Query: 1504 -SVKDGAICYK--PTKSKKLS 1521
S +G +C P K K LS
Sbjct: 145 VSSVEGTLCKTAIPYKRKYLS 165
Score = 43.9 bits (102), Expect = 0.001
Identities = 28/100 (28%), Positives = 52/100 (52%), Gaps = 10/100 (10%)
Query: 1239 CPSPVLNTPWIPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFV 1298
CPS + WI FQ+ CY F+ + + ++V +C + + ++SI +E+EN F+
Sbjct: 24 CPS----STWIQFQDSCYIFL--QEAIKVESIEDVRNQC--TDHGADMISIHNEEENAFI 75
Query: 1299 LEQLLYFNYMASWVMLGITY--RNKSLMWFDKTPLSYTHW 1336
L+ L ++LG+ Y + S WFD + +++ W
Sbjct: 76 LDTLKKQWKGPDDILLGMFYDTDDASFKWFDNSNMTFDKW 115
Score = 40.8 bits (94), Expect = 0.011
Identities = 25/118 (21%), Positives = 52/118 (44%), Gaps = 6/118 (5%)
Query: 365 WLPNNGFCYLLVNES---NSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNE-DIKEE 420
W+ CY+ + E+ S + +C +D+ISIH+ + ++ L + ++
Sbjct: 29 WIQFQDSCYIFLQEAIKVESIEDVRNQCTDHGADMISIHNEEENAFILDTLKKQWKGPDD 88
Query: 421 VWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYLGELGQWKVQSCE 478
+ +G+ F+W D + +T W + + + T C + G+WK +CE
Sbjct: 89 ILLGMFYDTDDASFKWFDNSNMTFDKWTDQDDDEDLVDT--CAFLHIKTGEWKKGNCE 144
Score = 36.2 bits (82), Expect = 0.28
Identities = 25/129 (19%), Positives = 56/129 (43%), Gaps = 13/129 (10%)
Query: 1104 ASETVKYLNNLYKIIPKTLTWHS---AKRECLKSNMQLVSITDPYQQAFLSVQALLHN-- 1158
+S +++ ++ Y + + + S + +C ++SI + + AF+ + L
Sbjct: 26 SSTWIQFQDSCYIFLQEAIKVESIEDVRNQCTDHGADMISIHNEEENAFI-LDTLKKQWK 84
Query: 1159 --SSLWIGLFSQDDELNFGWSDGKRLHFSRWAETNGQ---LEDCVVLD-TDGFWKTVDCN 1212
+ +G+F D+ +F W D + F +W + + ++ C L G WK +C
Sbjct: 85 GPDDILLGMFYDTDDASFKWFDNSNMTFDKWTDQDDDEDLVDTCAFLHIKTGEWKKGNCE 144
Query: 1213 -DNQPGAIC 1220
+ G +C
Sbjct: 145 VSSVEGTLC 153
Score = 35.0 bits (79), Expect = 0.63
Identities = 24/101 (23%), Positives = 45/101 (44%), Gaps = 12/101 (11%)
Query: 945 SAAKVQC-SEQWIPFQNKCFLKIKPVSL--TFSQASDTCHSYGGTLPSVLSQIEQDFITS 1001
+AA C S WI FQ+ C++ ++ + + C +G + S+ ++ E FI
Sbjct: 18 AAAVADCPSSTWIQFQDSCYIFLQEAIKVESIEDVRNQCTDHGADMISIHNEEENAFILD 77
Query: 1002 LL------PDMEATLWIGLRWTAYEKINKWTDNRELTYSNF 1036
L PD + +G+ + + KW DN +T+ +
Sbjct: 78 TLKKQWKGPD---DILLGMFYDTDDASFKWFDNSNMTFDKW 115
>gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens]
Length = 1321
Score = 84.0 bits (206), Expect = 1e-15
Identities = 55/190 (28%), Positives = 83/190 (43%), Gaps = 13/190 (6%)
Query: 161 DGNSYGRPCEFPFLIDGTWHH--DCILDEDHSGPWCATTLNYEY-----DRKWGICLKPE 213
+G YG C+ F + DC+ +G C +N C K
Sbjct: 1026 NGTMYGCSCDQGFAGENCEIDIDDCLCSPCENGGTCIDEVNGFVCLCLPSYGGSFCEKDT 1085
Query: 214 NGCEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKEKEGIA 273
GC+ W K + G CY++ +W++A C+ + L S++S E +++
Sbjct: 1086 EGCDRGWHKFQ--GHCYRYFAHRR-AWEDAEKDCRRRSGHLTSVHSPEEHSFINSFGH-- 1140
Query: 274 KIFWIGLNQLYSARGWEWSDHKPLNFLNWDPDRPSAPTIGGSSCARMDA-ESGLWQSFSC 332
+ WIGLN R ++W+D+ L F NW ++P GG C M A ESG W C
Sbjct: 1141 ENTWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVMVAHESGRWNDVPC 1200
Query: 333 EAQLPYVCRK 342
LPYVC+K
Sbjct: 1201 NYNLPYVCKK 1210
Score = 76.6 bits (187), Expect = 2e-13
Identities = 41/128 (32%), Positives = 59/128 (46%), Gaps = 6/128 (4%)
Query: 361 CDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEE 420
CD GW G CY +W+ A C+ S L S+HS + + + H E
Sbjct: 1088 CDRGWHKFQGHCYRYFAHRRAWEDAEKDCRRRSGHLTSVHSPEEHSFINSFGH-----EN 1142
Query: 421 VWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYLG-ELGQWKVQSCEE 479
WIGL + + FQW+D T + W EN+P+ + +CV + E G+W C
Sbjct: 1143 TWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVMVAHESGRWNDVPCNY 1202
Query: 480 KLKYVCKR 487
L YVCK+
Sbjct: 1203 NLPYVCKK 1210
Score = 59.3 bits (142), Expect = 3e-08
Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 10/115 (8%)
Query: 1109 KYLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITDPYQQAFLSVQALLHNSSLWIGLFSQ 1168
K+ + Y+ W A+++C + + L S+ P + +F++ + + WIGL +
Sbjct: 1094 KFQGHCYRYFAHRRAWEDAEKDCRRRSGHLTSVHSPEEHSFINS---FGHENTWIGLNDR 1150
Query: 1169 DDELNFGWSDGKRLHFSRWAETNGQL-----EDCVVL--DTDGFWKTVDCNDNQP 1216
E +F W+D L F W E EDCVV+ G W V CN N P
Sbjct: 1151 IVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVMVAHESGRWNDVPCNYNLP 1205
Score = 56.6 bits (135), Expect = 2e-07
Identities = 32/135 (23%), Positives = 61/135 (45%), Gaps = 19/135 (14%)
Query: 1539 WIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRV 1598
W +++GHCY+ ++ +A+K C + S + S+ +E+ F++ EN
Sbjct: 1092 WHKFQGHCYRYFAHRRAWEDAEKDCRR--RSGHLTSVHSPEEHSFINSFGHEN------T 1143
Query: 1599 WLGLSQHSVDQSWSWLDGSEVTFVKWENKSK----SGVGRCSMLIA-SNETWKKVECEHG 1653
W+GL+ V++ + W D + + F W +G C +++A + W V C +
Sbjct: 1144 WIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVMVAHESGRWNDVPCNYN 1203
Query: 1654 F------GRVVCKVP 1662
G V+C P
Sbjct: 1204 LPYVCKKGTVLCGPP 1218
Score = 50.1 bits (118), Expect = 2e-05
Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 15/95 (15%)
Query: 638 KPDDPCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEF 697
K + C GW F CY+ F +R WE+AE+ C+ HL+S +E
Sbjct: 1083 KDTEGCDRGWHKFQGH--CYRYF-----AHRRAWEDAEKDCRRRSGHLTSVHSPEE---- 1131
Query: 698 LHFLTDQFSGQHWLWIGLNKRSPDLQGSWQWSDRT 732
H + F G WIGLN R ++ +QW+D T
Sbjct: 1132 -HSFINSF-GHENTWIGLNDRI--VERDFQWTDNT 1162
Score = 46.2 bits (108), Expect = 3e-04
Identities = 46/175 (26%), Positives = 67/175 (38%), Gaps = 29/175 (16%)
Query: 951 CSEQWIPFQNKCFLKIKPVSLTFSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATL 1010
C W FQ C+ + + A C G L SV S E FI S +
Sbjct: 1088 CDRGWHKFQGHCY-RYFAHRRAWEDAEKDCRRRSGHLTSVHSPEEHSFINSFGHE---NT 1143
Query: 1011 WIGLRWTAYEKINKWTDNRELTYSNFHPLLVSGRLRIPENFFEEESRYHCALILNLQKSP 1070
WIGL E+ +WTDN L + N+ R P+NFF C +++ +
Sbjct: 1144 WIGLNDRIVERDFQWTDNTGLQFENW-------RENQPDNFF--AGGEDCVVMVAHE--- 1191
Query: 1071 FTGTWNFTSCSE------RHFVSLC------QKYSEVKSRQTLQNASETVKYLNN 1113
+G WN C+ + LC + S + +R+ N TV+Y N
Sbjct: 1192 -SGRWNDVPCNYNLPYVCKKGTVLCGPPPAVENASLIGARKAKYNVHATVRYQCN 1245
Score = 44.7 bits (104), Expect = 8e-04
Identities = 32/145 (22%), Positives = 57/145 (39%), Gaps = 29/145 (20%)
Query: 1211 CNDNQPGAICY----YSGNETEKEVKPVDSVKCPSPVLNTPWIPFQNCCYNFIITKNRHM 1266
C D G +C Y G+ EK+ + D W FQ CY + +
Sbjct: 1061 CIDEVNGFVCLCLPSYGGSFCEKDTEGCDR----------GWHKFQGHCYRYFAHRR--- 1107
Query: 1267 ATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNYMASWVMLGITYRNKSLMWF 1326
++ C++ + H+ S+ +E++F+ F + +W+ L + W
Sbjct: 1108 --AWEDAEKDCRRRS--GHLTSVHSPEEHSFINS----FGHENTWIGLNDRIVERDFQWT 1159
Query: 1327 DKTPLSYTHWRAGRPTIKNEKFLAG 1351
D T L + +WR +P + F AG
Sbjct: 1160 DNTGLQFENWRENQP----DNFFAG 1180
Score = 43.1 bits (100), Expect = 0.002
Identities = 27/112 (24%), Positives = 45/112 (40%), Gaps = 14/112 (12%)
Query: 1401 YEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHD 1460
++ Y + W +A C + GHL SVH+ F+ + W+GL+
Sbjct: 1095 FQGHCYRYFAHRRAWEDAEKDCRRRSGHLTSVHSPEEHSFINSFGHEN---TWIGLNDRI 1151
Query: 1461 GSESSFEWSDGSTFDYIPWKGQTSPGN-------CVLL--DPKGTWKHEKCN 1503
E F+W+D + + W+ + P N CV++ G W CN
Sbjct: 1152 -VERDFQWTDNTGLQFENWR-ENQPDNFFAGGEDCVVMVAHESGRWNDVPCN 1201
>gi|38372935 brevican isoform 1 [Homo sapiens]
Length = 911
Score = 75.5 bits (184), Expect = 4e-13
Identities = 50/173 (28%), Positives = 76/173 (43%), Gaps = 19/173 (10%)
Query: 182 DCILDEDHSGPWCATTLNYEYDRKWGICLKPENG---------CEDNWEKNEQFGSCYQF 232
DC+ H+G C E + +CL G C W+ + G+CY+
Sbjct: 649 DCVPSPCHNGGTCLE----EEEGVRCLCLPGYGGDLCDVGLRFCNPGWDAFQ--GACYK- 701
Query: 233 NTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKEKEGIAKIFWIGLNQLYSARGWEWS 292
+ T SW+EA C+ GA L SI++ E ++ + + WIGLN + WS
Sbjct: 702 HFSTRRSWEEAETQCRMYGAHLASISTPEEQDFINNR--YREYQWIGLNDRTIEGDFLWS 759
Query: 293 DHKPLNFLNWDPDRPSAPTIGGSSCARMD-AESGLWQSFSCEAQLPYVCRKPL 344
D PL + NW+P +P + + G +C M + G W C L Y C+ L
Sbjct: 760 DGVPLLYENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVPCNYHLSYTCKMGL 812
Score = 72.8 bits (177), Expect = 3e-12
Identities = 38/127 (29%), Positives = 59/127 (46%), Gaps = 6/127 (4%)
Query: 361 CDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEE 420
C+ GW G CY + SW++A +C+ + + L SI + + + + N +E
Sbjct: 688 CNPGWDAFQGACYKHFSTRRSWEEAETQCRMYGAHLASISTPEEQDFI-----NNRYREY 742
Query: 421 VWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYL-GELGQWKVQSCEE 479
WIGL + I F WSDG + W+ +P+ + NCV + + GQW C
Sbjct: 743 QWIGLNDRTIEGDFLWSDGVPLLYENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVPCNY 802
Query: 480 KLKYVCK 486
L Y CK
Sbjct: 803 HLSYTCK 809
Score = 59.3 bits (142), Expect = 3e-08
Identities = 34/92 (36%), Positives = 52/92 (56%), Gaps = 15/92 (16%)
Query: 643 CPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFLT 702
C GW +F + CYK F +R+WEEAE C+ GAHL+S S +E F+
Sbjct: 688 CNPGWDAFQGA--CYKHFST-----RRSWEEAETQCRMYGAHLASISTPEE----QDFIN 736
Query: 703 DQFSGQHWLWIGLNKRSPDLQGSWQWSDRTPV 734
+++ + + WIGLN R+ ++G + WSD P+
Sbjct: 737 NRY--REYQWIGLNDRT--IEGDFLWSDGVPL 764
Score = 49.3 bits (116), Expect = 3e-05
Identities = 32/130 (24%), Positives = 54/130 (41%), Gaps = 14/130 (10%)
Query: 1539 WIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRV 1598
W ++G CYK S+ EA+ C + A + SI +E F++ RE
Sbjct: 692 WDAFQGACYKHFSTRRSWEEAETQCRMY--GAHLASISTPEEQDFINNRYREYQ------ 743
Query: 1599 WLGLSQHSVDQSWSWLDGSEVTFVKW-----ENKSKSGVGRCSMLIASNETWKKVECEHG 1653
W+GL+ +++ + W DG + + W ++ SG M+ W V C +
Sbjct: 744 WIGLNDRTIEGDFLWSDGVPLLYENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVPCNYH 803
Query: 1654 FGRVVCKVPL 1663
CK+ L
Sbjct: 804 LS-YTCKMGL 812
Score = 48.9 bits (115), Expect = 4e-05
Identities = 34/107 (31%), Positives = 48/107 (44%), Gaps = 14/107 (13%)
Query: 1115 YKIIPKTLTWHSAKRECLKSNMQLVSITDPYQQAFLSVQALLHNSSLWIGLFSQDDELNF 1174
YK +W A+ +C L SI+ P +Q F++ + + WIGL + E +F
Sbjct: 700 YKHFSTRRSWEEAETQCRMYGAHLASISTPEEQDFINNR---YREYQWIGLNDRTIEGDF 756
Query: 1175 GWSDGKRLHFSRWAETNGQL-------EDCVVL--DTDGFWKTVDCN 1212
WSDG L + W GQ E+CVV+ G W V CN
Sbjct: 757 LWSDGVPLLYENW--NPGQPDSYFLSGENCVVMVWHDQGQWSDVPCN 801
Score = 48.1 bits (113), Expect = 7e-05
Identities = 28/88 (31%), Positives = 41/88 (46%), Gaps = 4/88 (4%)
Query: 951 CSEQWIPFQNKCFLKIKPVSLTFSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATL 1010
C+ W FQ C+ K ++ +A C YG L S+ + EQDFI + + +
Sbjct: 688 CNPGWDAFQGACY-KHFSTRRSWEEAETQCRMYGAHLASISTPEEQDFINNRYREYQ--- 743
Query: 1011 WIGLRWTAYEKINKWTDNRELTYSNFHP 1038
WIGL E W+D L Y N++P
Sbjct: 744 WIGLNDRTIEGDFLWSDGVPLLYENWNP 771
Score = 47.4 bits (111), Expect = 1e-04
Identities = 34/116 (29%), Positives = 48/116 (41%), Gaps = 12/116 (10%)
Query: 1396 PQFMPYEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVG 1455
P + ++ Y + +W EA C G HLAS+ Q F+ + + W+G
Sbjct: 690 PGWDAFQGACYKHFSTRRSWEEAETQCRMYGAHLASISTPEEQDFINNRYRE---YQWIG 746
Query: 1456 LSSHDGSESSFEWSDGSTFDYIPWK-GQ-----TSPGNCVLL--DPKGTWKHEKCN 1503
L+ E F WSDG Y W GQ S NCV++ +G W CN
Sbjct: 747 LNDRT-IEGDFLWSDGVPLLYENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVPCN 801
Score = 45.8 bits (107), Expect = 4e-04
Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 14/107 (13%)
Query: 1245 NTPWIPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLY 1304
N W FQ CY T+ + +E T+C+ +H+ SI +E +F+ + Y
Sbjct: 689 NPGWDAFQGACYKHFSTRR-----SWEEAETQCRMYG--AHLASISTPEEQDFINNR--Y 739
Query: 1305 FNYMASWVMLGITYRNKSLMWFDKTPLSYTHWRAGRPTIKNEKFLAG 1351
Y W+ L +W D PL Y +W G+P + FL+G
Sbjct: 740 REYQ--WIGLNDRTIEGDFLWSDGVPLLYENWNPGQP---DSYFLSG 781
Score = 35.4 bits (80), Expect = 0.48
Identities = 38/157 (24%), Positives = 61/157 (38%), Gaps = 33/157 (21%)
Query: 499 KMCPPDEGWKRHGETCYKIYEDEVPFG---TNCNL------TITSRFEQEYLNDLMKKYD 549
+ C P GW CYK + + T C + +I++ EQ+++N+
Sbjct: 686 RFCNP--GWDAFQGACYKHFSTRRSWEEAETQCRMYGAHLASISTPEEQDFINN------ 737
Query: 550 KSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFLEP----ASPGGCVAMSTGKS 605
R+Y W GL D G++ W+ + + NWN +P S CV M
Sbjct: 738 -RYREYQWIGLNDRTIEGDFLWSD----GVPLLYENWNPGQPDSYFLSGENCVVM-VWHD 791
Query: 606 VGKWEVKDCRSFKALSICKKMSGPLGPEEASPKPDDP 642
G+W C ++ CK +G P P+ P
Sbjct: 792 QGQWSDVPC-NYHLSYTCK-----MGLVSCGPPPELP 822
>gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]
Length = 2416
Score = 70.5 bits (171), Expect = 1e-11
Identities = 49/187 (26%), Positives = 77/187 (41%), Gaps = 13/187 (6%)
Query: 302 WDPDRPSAPTIGGSSCARMDAESGLWQSFSCEAQLPYVCRKPLNNTVELTDVWTYSDTRC 361
W + S SCA +G + E + +C P T E ++ C
Sbjct: 2154 WKRESESTAAAPARSCAEEPCGAGTCK----ETEGHVICLCPPGYTGEHCNI---DQEVC 2206
Query: 362 DAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEEV 421
+ GW G CY + +W A +C+ S L SI + + E V N + ++
Sbjct: 2207 EEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFV-----NNNAQDYQ 2261
Query: 422 WIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYL-GELGQWKVQSCEEK 480
WIGL + I F+WSDG + W N+P+ + +CV + E G+W C
Sbjct: 2262 WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYH 2321
Query: 481 LKYVCKR 487
L + CK+
Sbjct: 2322 LPFTCKK 2328
Score = 68.6 bits (166), Expect = 5e-11
Identities = 41/135 (30%), Positives = 59/135 (43%), Gaps = 6/135 (4%)
Query: 209 CLKPENGCEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKE 268
C + CE+ W K + G CY+ +W +A C+ Q + L SI + E ++
Sbjct: 2199 CNIDQEVCEEGWNKYQ--GHCYRHFPDRE-TWVDAERRCREQQSHLSSIVTPEEQEFVNN 2255
Query: 269 KEGIAKIFWIGLNQLYSARGWEWSDHKPLNFLNWDPDRPSAPTIGGSSCARMD-AESGLW 327
+ WIGLN + WSD P+ F NW P++P G C M E G W
Sbjct: 2256 NAQDYQ--WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEW 2313
Query: 328 QSFSCEAQLPYVCRK 342
C LP+ C+K
Sbjct: 2314 NDVPCNYHLPFTCKK 2328
Score = 63.2 bits (152), Expect = 2e-09
Identities = 39/115 (33%), Positives = 51/115 (44%), Gaps = 10/115 (8%)
Query: 1109 KYLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITDPYQQAFLSVQALLHNSSLWIGLFSQ 1168
KY + Y+ P TW A+R C + L SI P +Q F++ A WIGL +
Sbjct: 2212 KYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNA---QDYQWIGLNDR 2268
Query: 1169 DDELNFGWSDGKRLHFSRWAETN-----GQLEDCVVL--DTDGFWKTVDCNDNQP 1216
E +F WSDG + F W EDCVV+ G W V CN + P
Sbjct: 2269 TIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLP 2323
Score = 54.3 bits (129), Expect = 1e-06
Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 19/135 (14%)
Query: 1539 WIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRV 1598
W +Y+GHCY+ ++ +A++ C + + + SI +E +FV NNN
Sbjct: 2210 WNKYQGHCYRHFPDRETWVDAERRC--REQQSHLSSIVTPEEQEFV------NNNAQDYQ 2261
Query: 1599 WLGLSQHSVDQSWSWLDGSEVTFVKW-----ENKSKSGVGRCSMLIASNETWKKVECEHG 1653
W+GL+ +++ + W DG + F W +N +G M+ W V C +
Sbjct: 2262 WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYH 2321
Query: 1654 F------GRVVCKVP 1662
G V C P
Sbjct: 2322 LPFTCKKGTVACGEP 2336
Score = 52.4 bits (124), Expect = 4e-06
Identities = 46/170 (27%), Positives = 74/170 (43%), Gaps = 23/170 (13%)
Query: 614 CRSFKALSICKKMSGPLGPEEASPKPDDPCPEGWQSFPASLSCYKVFHAERIVRKRNWEE 673
C+ + IC G G E + C EGW + CY+ F + W +
Sbjct: 2179 CKETEGHVICLCPPGYTG--EHCNIDQEVCEEGWNKYQGH--CYRHFPD-----RETWVD 2229
Query: 674 AERFCQALGAHLSSFSHVDEIKEFLHFLTDQFSGQHWLWIGLNKRSPDLQGSWQWSDRTP 733
AER C+ +HLSS +E +EF++ + Q + WIGLN R+ ++G ++WSD P
Sbjct: 2230 AERRCREQQSHLSSIVTPEE-QEFVN-----NNAQDYQWIGLNDRT--IEGDFRWSDGHP 2281
Query: 734 VS-TIIMPNEFQQDYDIRDCAAVKVFHRPWRRGWHFYDDREFIYLRPFAC 782
+ PN+ + + V ++H ++D Y PF C
Sbjct: 2282 MQFENWRPNQPDNFFAAGEDCVVMIWHEKGE-----WNDVPCNYHLPFTC 2326
Score = 51.2 bits (121), Expect = 8e-06
Identities = 37/141 (26%), Positives = 60/141 (42%), Gaps = 18/141 (12%)
Query: 951 CSEQWIPFQNKCFLKIKPVSLTFSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATL 1010
C E W +Q C+ P T+ A C L S+++ EQ+F+ + D +
Sbjct: 2206 CEEGWNKYQGHCYRHF-PDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ--- 2261
Query: 1011 WIGLRWTAYEKINKWTDNRELTYSNFHPLLVSGRLRIPENFFEEESRYHCALILNLQKSP 1070
WIGL E +W+D + + N+ P P+NFF + C +++ +K
Sbjct: 2262 WIGLNDRTIEGDFRWSDGHPMQFENWRP-------NQPDNFF--AAGEDCVVMIWHEK-- 2310
Query: 1071 FTGTWNFTSCSERHFVSLCQK 1091
G WN C+ H C+K
Sbjct: 2311 --GEWNDVPCN-YHLPFTCKK 2328
Score = 44.7 bits (104), Expect = 8e-04
Identities = 34/133 (25%), Positives = 52/133 (39%), Gaps = 21/133 (15%)
Query: 1380 CKIEMVDYKEEYNTTLPQFMPYEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQL 1439
C I+ +E +N Y+ Y + TW +A C + HL+S+ Q
Sbjct: 2199 CNIDQEVCEEGWNK-------YQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQE 2251
Query: 1440 FLEDIVKRDGFPLWVGLSSHDGSESSFEWSDGSTFDYIPWKGQTSPGN-------CVLL- 1491
F+ + + W+GL+ E F WSDG + W+ P N CV++
Sbjct: 2252 FVNNNAQD---YQWIGLNDRT-IEGDFRWSDGHPMQFENWR-PNQPDNFFAAGEDCVVMI 2306
Query: 1492 -DPKGTWKHEKCN 1503
KG W CN
Sbjct: 2307 WHEKGEWNDVPCN 2319
Score = 38.1 bits (87), Expect = 0.074
Identities = 34/135 (25%), Positives = 56/135 (41%), Gaps = 26/135 (19%)
Query: 504 DEGWKRHGETCYKIYEDE---VPFGTNCN------LTITSRFEQEYLNDLMKKYDKSLRK 554
+EGW ++ CY+ + D V C +I + EQE++N+ + +
Sbjct: 2207 EEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNN-------NAQD 2259
Query: 555 YFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFLEP----ASPGGCVAMSTGKSVGKWE 610
Y W GL D G++ W+ + F NW +P A+ CV M + G+W
Sbjct: 2260 YQWIGLNDRTIEGDFRWSD----GHPMQFENWRPNQPDNFFAAGEDCVVMIWHEK-GEWN 2314
Query: 611 VKDCRSFKALSICKK 625
C ++ CKK
Sbjct: 2315 DVPC-NYHLPFTCKK 2328
Score = 33.1 bits (74), Expect = 2.4
Identities = 22/94 (23%), Positives = 35/94 (37%), Gaps = 11/94 (11%)
Query: 1248 WIPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNY 1307
W +Q CY RH + V + + +SH+ SI +E FV +
Sbjct: 2210 WNKYQGHCY-------RHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ- 2261
Query: 1308 MASWVMLGITYRNKSLMWFDKTPLSYTHWRAGRP 1341
W+ L W D P+ + +WR +P
Sbjct: 2262 ---WIGLNDRTIEGDFRWSDGHPMQFENWRPNQP 2292
>gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]
Length = 2317
Score = 68.2 bits (165), Expect = 7e-11
Identities = 40/128 (31%), Positives = 57/128 (44%), Gaps = 6/128 (4%)
Query: 216 CEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKEKEGIAKI 275
CE+ W K + G CY+ +W +A C+ Q + L SI + E ++ +
Sbjct: 2168 CEEGWNKYQ--GHCYRHFPDRE-TWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ- 2223
Query: 276 FWIGLNQLYSARGWEWSDHKPLNFLNWDPDRPSAPTIGGSSCARMD-AESGLWQSFSCEA 334
WIGLN + WSD P+ F NW P++P G C M E G W C
Sbjct: 2224 -WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNY 2282
Query: 335 QLPYVCRK 342
LP+ C+K
Sbjct: 2283 HLPFTCKK 2290
Score = 67.8 bits (164), Expect = 9e-11
Identities = 38/128 (29%), Positives = 59/128 (46%), Gaps = 6/128 (4%)
Query: 361 CDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEE 420
C+ GW G CY + +W A +C+ S L SI + + E V N + ++
Sbjct: 2168 CEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFV-----NNNAQDY 2222
Query: 421 VWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYL-GELGQWKVQSCEE 479
WIGL + I F+WSDG + W N+P+ + +CV + E G+W C
Sbjct: 2223 QWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNY 2282
Query: 480 KLKYVCKR 487
L + CK+
Sbjct: 2283 HLPFTCKK 2290
Score = 63.2 bits (152), Expect = 2e-09
Identities = 39/115 (33%), Positives = 51/115 (44%), Gaps = 10/115 (8%)
Query: 1109 KYLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITDPYQQAFLSVQALLHNSSLWIGLFSQ 1168
KY + Y+ P TW A+R C + L SI P +Q F++ A WIGL +
Sbjct: 2174 KYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNA---QDYQWIGLNDR 2230
Query: 1169 DDELNFGWSDGKRLHFSRWAETN-----GQLEDCVVL--DTDGFWKTVDCNDNQP 1216
E +F WSDG + F W EDCVV+ G W V CN + P
Sbjct: 2231 TIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLP 2285
Score = 54.7 bits (130), Expect = 8e-07
Identities = 52/204 (25%), Positives = 82/204 (40%), Gaps = 30/204 (14%)
Query: 905 LYMSAKTWLIDLG-KPTDCSTKLPFICEKYNVSSLEKYSPDSAAKVQ--CSEQWIPFQNK 961
LY +T ++ PTD S S K +S A Q C E W +Q
Sbjct: 2128 LYSGEETHTVETATSPTDASIP---------ASPEWKRESESTAADQEVCEEGWNKYQGH 2178
Query: 962 CFLKIKPVSLTFSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATLWIGLRWTAYEK 1021
C+ P T+ A C L S+++ EQ+F+ + D + WIGL E
Sbjct: 2179 CYRHF-PDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ---WIGLNDRTIEG 2234
Query: 1022 INKWTDNRELTYSNFHPLLVSGRLRIPENFFEEESRYHCALILNLQKSPFTGTWNFTSCS 1081
+W+D + + N+ P P+NFF + C +++ +K G WN C+
Sbjct: 2235 DFRWSDGHPMQFENWRP-------NQPDNFF--AAGEDCVVMIWHEK----GEWNDVPCN 2281
Query: 1082 ERHFVSLCQKYSEVKSRQTLQNAS 1105
H C+K + ++ LQ S
Sbjct: 2282 -YHLPFTCKKGTATTYKRRLQKRS 2304
Score = 54.3 bits (129), Expect = 1e-06
Identities = 44/160 (27%), Positives = 72/160 (45%), Gaps = 26/160 (16%)
Query: 629 PLGPE-----EASPKPDDPCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGA 683
P PE E++ + C EGW + CY+ F + W +AER C+ +
Sbjct: 2149 PASPEWKRESESTAADQEVCEEGWNKYQGH--CYRHFPD-----RETWVDAERRCREQQS 2201
Query: 684 HLSSFSHVDEIKEFLHFLTDQFSGQHWLWIGLNKRSPDLQGSWQWSDRTPVS-TIIMPNE 742
HLSS +E +EF++ + Q + WIGLN R+ ++G ++WSD P+ PN+
Sbjct: 2202 HLSSIVTPEE-QEFVN-----NNAQDYQWIGLNDRT--IEGDFRWSDGHPMQFENWRPNQ 2253
Query: 743 FQQDYDIRDCAAVKVFHRPWRRGWHFYDDREFIYLRPFAC 782
+ + V ++H ++D Y PF C
Sbjct: 2254 PDNFFAAGEDCVVMIWHEKGE-----WNDVPCNYHLPFTC 2288
Score = 53.5 bits (127), Expect = 2e-06
Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 13/119 (10%)
Query: 1539 WIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRV 1598
W +Y+GHCY+ ++ +A++ C + + + SI +E +FV NNN
Sbjct: 2172 WNKYQGHCYRHFPDRETWVDAERRC--REQQSHLSSIVTPEEQEFV------NNNAQDYQ 2223
Query: 1599 WLGLSQHSVDQSWSWLDGSEVTFVKW-----ENKSKSGVGRCSMLIASNETWKKVECEH 1652
W+GL+ +++ + W DG + F W +N +G M+ W V C +
Sbjct: 2224 WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNY 2282
Score = 47.0 bits (110), Expect = 2e-04
Identities = 39/143 (27%), Positives = 55/143 (38%), Gaps = 20/143 (13%)
Query: 1401 YEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHD 1460
Y+ Y + TW +A C + HL+S+ Q F+ + + W+GL+
Sbjct: 2175 YQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQD---YQWIGLNDRT 2231
Query: 1461 GSESSFEWSDGSTFDYIPWKGQTSPGN-------CVLL--DPKGTWKHEKCN------SV 1505
E F WSDG + W+ P N CV++ KG W CN
Sbjct: 2232 -IEGDFRWSDGHPMQFENWR-PNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCK 2289
Query: 1506 KDGAICYKPTKSKKLSRLTYSSR 1528
K A YK K+ SR SR
Sbjct: 2290 KGTATTYKRRLQKRSSRHPRRSR 2312
Score = 41.2 bits (95), Expect = 0.009
Identities = 38/151 (25%), Positives = 64/151 (42%), Gaps = 28/151 (18%)
Query: 488 KGEKLNDASSDKMCPPDEGWKRHGETCYKIYEDE---VPFGTNCN------LTITSRFEQ 538
K E + A+ ++C +EGW ++ CY+ + D V C +I + EQ
Sbjct: 2155 KRESESTAADQEVC--EEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQ 2212
Query: 539 EYLNDLMKKYDKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFLEP----ASP 594
E++N+ + + Y W GL D G++ W+ + F NW +P A+
Sbjct: 2213 EFVNN-------NAQDYQWIGLNDRTIEGDFRWSD----GHPMQFENWRPNQPDNFFAAG 2261
Query: 595 GGCVAMSTGKSVGKWEVKDCRSFKALSICKK 625
CV M + G+W C ++ CKK
Sbjct: 2262 EDCVVMIWHEK-GEWNDVPC-NYHLPFTCKK 2290
Score = 35.8 bits (81), Expect = 0.37
Identities = 33/137 (24%), Positives = 47/137 (34%), Gaps = 28/137 (20%)
Query: 1222 YSGNET---EKEVKPVDSVKCPSP--------------VLNTPWIPFQNCCYNFIITKNR 1264
YSG ET E P D+ SP V W +Q CY R
Sbjct: 2129 YSGEETHTVETATSPTDASIPASPEWKRESESTAADQEVCEEGWNKYQGHCY-------R 2181
Query: 1265 HMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNYMASWVMLGITYRNKSLM 1324
H + V + + +SH+ SI +E FV + W+ L
Sbjct: 2182 HFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ----WIGLNDRTIEGDFR 2237
Query: 1325 WFDKTPLSYTHWRAGRP 1341
W D P+ + +WR +P
Sbjct: 2238 WSDGHPMQFENWRPNQP 2254
>gi|187607300 versican isoform 2 [Homo sapiens]
Length = 655
Score = 67.0 bits (162), Expect = 1e-10
Identities = 40/136 (29%), Positives = 60/136 (44%), Gaps = 6/136 (4%)
Query: 208 ICLKPENGCEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLK 267
+C + C+ W K + G CY++ +W A C+ QGA L SI S E ++
Sbjct: 420 LCEQDTETCDYGWHKFQ--GQCYKYFAHRR-TWDAAERECRLQGAHLTSILSHEEQMFVN 476
Query: 268 EKEGIAKIFWIGLNQLYSARGWEWSDHKPLNFLNWDPDRPSAPTIGGSSCARMD-AESGL 326
+ WIGLN + W+D L + NW P++P + G C + E+G
Sbjct: 477 RVGHDYQ--WIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQ 534
Query: 327 WQSFSCEAQLPYVCRK 342
W C L Y C+K
Sbjct: 535 WNDVPCNYHLTYTCKK 550
Score = 66.6 bits (161), Expect = 2e-10
Identities = 39/128 (30%), Positives = 57/128 (44%), Gaps = 6/128 (4%)
Query: 361 CDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEE 420
CD GW G CY +WD A +C+ + L SI S + V H+
Sbjct: 428 CDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQ---- 483
Query: 421 VWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYL-GELGQWKVQSCEE 479
WIGL + F+W+DG+ + W N+P+ ++ +CV + E GQW C
Sbjct: 484 -WIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNY 542
Query: 480 KLKYVCKR 487
L Y CK+
Sbjct: 543 HLTYTCKK 550
Score = 57.4 bits (137), Expect = 1e-07
Identities = 35/111 (31%), Positives = 49/111 (44%), Gaps = 10/111 (9%)
Query: 1109 KYLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITDPYQQAFLSVQALLHNSSLWIGLFSQ 1168
K+ YK TW +A+REC L SI +Q F++ + + WIGL +
Sbjct: 434 KFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVN---RVGHDYQWIGLNDK 490
Query: 1169 DDELNFGWSDGKRLHFSRWAETNGQL-----EDCVVL--DTDGFWKTVDCN 1212
E +F W+DG L + W EDCVV+ +G W V CN
Sbjct: 491 MFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCN 541
Score = 55.8 bits (133), Expect = 3e-07
Identities = 45/167 (26%), Positives = 70/167 (41%), Gaps = 18/167 (10%)
Query: 951 CSEQWIPFQNKCFLKIKPVSLTFSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATL 1010
C W FQ +C+ K T+ A C G L S+LS EQ F+ + D +
Sbjct: 428 CDYGWHKFQGQCY-KYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQ--- 483
Query: 1011 WIGLRWTAYEKINKWTDNRELTYSNFHPLLVSGRLRIPENFFEEESRYHCALILNLQKSP 1070
WIGL +E +WTD L Y N+ P P++FF + C +I+ +
Sbjct: 484 WIGLNDKMFEHDFRWTDGSTLQYENWRP-------NQPDSFF--SAGEDCVVIIWHE--- 531
Query: 1071 FTGTWNFTSCSERHFVSLCQKYSEVKSRQTLQNASETVKYLNNLYKI 1117
G WN C+ H C+K + + + ++T + Y+I
Sbjct: 532 -NGQWNDVPCN-YHLTYTCKKGTVACGQPPVVENAKTFGKMKPRYEI 576
Score = 48.1 bits (113), Expect = 7e-05
Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 17/91 (18%)
Query: 641 DPCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSS-FSHVDEIKEFLH 699
+ C GW F CYK F +R W+ AER C+ GAHL+S SH +++ F++
Sbjct: 426 ETCDYGWHKFQGQ--CYKYF-----AHRRTWDAAERECRLQGAHLTSILSHEEQM--FVN 476
Query: 700 FLTDQFSGQHWLWIGLNKRSPDLQGSWQWSD 730
+ G + WIGLN + + ++W+D
Sbjct: 477 RV-----GHDYQWIGLNDKM--FEHDFRWTD 500
Score = 47.0 bits (110), Expect = 2e-04
Identities = 32/112 (28%), Positives = 47/112 (41%), Gaps = 14/112 (12%)
Query: 1401 YEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPL-WVGLSSH 1459
++ Y + TW A C G HL S+ + Q+F V R G W+GL+
Sbjct: 435 FQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMF----VNRVGHDYQWIGLNDK 490
Query: 1460 DGSESSFEWSDGSTFDYIPWKGQ------TSPGNCVLL--DPKGTWKHEKCN 1503
E F W+DGST Y W+ ++ +CV++ G W CN
Sbjct: 491 M-FEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCN 541
Score = 46.6 bits (109), Expect = 2e-04
Identities = 33/135 (24%), Positives = 54/135 (40%), Gaps = 19/135 (14%)
Query: 1539 WIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRV 1598
W +++G CYK ++ A++ C A + SI +E FV+R+ +
Sbjct: 432 WHKFQGQCYKYFAHRRTWDAAERECRLQ--GAHLTSILSHEEQMFVNRVGHDYQ------ 483
Query: 1599 WLGLSQHSVDQSWSWLDGSEVTFVKWENKSK----SGVGRCSMLI-ASNETWKKVECEHG 1653
W+GL+ + + W DGS + + W S C ++I N W V C +
Sbjct: 484 WIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYH 543
Query: 1654 F------GRVVCKVP 1662
G V C P
Sbjct: 544 LTYTCKKGTVACGQP 558
Score = 34.7 bits (78), Expect = 0.82
Identities = 23/94 (24%), Positives = 35/94 (37%), Gaps = 11/94 (11%)
Query: 1248 WIPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNY 1307
W FQ CY + + T D +C+ +H+ SI +E FV +
Sbjct: 432 WHKFQGQCYKYFAHRR-----TWDAAERECRLQG--AHLTSILSHEEQMFVNR----VGH 480
Query: 1308 MASWVMLGITYRNKSLMWFDKTPLSYTHWRAGRP 1341
W+ L W D + L Y +WR +P
Sbjct: 481 DYQWIGLNDKMFEHDFRWTDGSTLQYENWRPNQP 514
>gi|21361116 versican isoform 1 [Homo sapiens]
Length = 3396
Score = 67.0 bits (162), Expect = 1e-10
Identities = 40/136 (29%), Positives = 60/136 (44%), Gaps = 6/136 (4%)
Query: 208 ICLKPENGCEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLK 267
+C + C+ W K + G CY++ +W A C+ QGA L SI S E ++
Sbjct: 3161 LCEQDTETCDYGWHKFQ--GQCYKYFAHRR-TWDAAERECRLQGAHLTSILSHEEQMFVN 3217
Query: 268 EKEGIAKIFWIGLNQLYSARGWEWSDHKPLNFLNWDPDRPSAPTIGGSSCARMD-AESGL 326
+ WIGLN + W+D L + NW P++P + G C + E+G
Sbjct: 3218 RVGHDYQ--WIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQ 3275
Query: 327 WQSFSCEAQLPYVCRK 342
W C L Y C+K
Sbjct: 3276 WNDVPCNYHLTYTCKK 3291
Score = 66.6 bits (161), Expect = 2e-10
Identities = 39/128 (30%), Positives = 57/128 (44%), Gaps = 6/128 (4%)
Query: 361 CDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEE 420
CD GW G CY +WD A +C+ + L SI S + V H+
Sbjct: 3169 CDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQ---- 3224
Query: 421 VWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYL-GELGQWKVQSCEE 479
WIGL + F+W+DG+ + W N+P+ ++ +CV + E GQW C
Sbjct: 3225 -WIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNY 3283
Query: 480 KLKYVCKR 487
L Y CK+
Sbjct: 3284 HLTYTCKK 3291
Score = 57.4 bits (137), Expect = 1e-07
Identities = 35/111 (31%), Positives = 49/111 (44%), Gaps = 10/111 (9%)
Query: 1109 KYLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITDPYQQAFLSVQALLHNSSLWIGLFSQ 1168
K+ YK TW +A+REC L SI +Q F++ + + WIGL +
Sbjct: 3175 KFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVN---RVGHDYQWIGLNDK 3231
Query: 1169 DDELNFGWSDGKRLHFSRWAETNGQL-----EDCVVL--DTDGFWKTVDCN 1212
E +F W+DG L + W EDCVV+ +G W V CN
Sbjct: 3232 MFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCN 3282
Score = 55.8 bits (133), Expect = 3e-07
Identities = 45/167 (26%), Positives = 70/167 (41%), Gaps = 18/167 (10%)
Query: 951 CSEQWIPFQNKCFLKIKPVSLTFSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATL 1010
C W FQ +C+ K T+ A C G L S+LS EQ F+ + D +
Sbjct: 3169 CDYGWHKFQGQCY-KYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQ--- 3224
Query: 1011 WIGLRWTAYEKINKWTDNRELTYSNFHPLLVSGRLRIPENFFEEESRYHCALILNLQKSP 1070
WIGL +E +WTD L Y N+ P P++FF + C +I+ +
Sbjct: 3225 WIGLNDKMFEHDFRWTDGSTLQYENWRP-------NQPDSFF--SAGEDCVVIIWHE--- 3272
Query: 1071 FTGTWNFTSCSERHFVSLCQKYSEVKSRQTLQNASETVKYLNNLYKI 1117
G WN C+ H C+K + + + ++T + Y+I
Sbjct: 3273 -NGQWNDVPCN-YHLTYTCKKGTVACGQPPVVENAKTFGKMKPRYEI 3317
Score = 48.1 bits (113), Expect = 7e-05
Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 17/91 (18%)
Query: 641 DPCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSS-FSHVDEIKEFLH 699
+ C GW F CYK F +R W+ AER C+ GAHL+S SH +++ F++
Sbjct: 3167 ETCDYGWHKFQGQ--CYKYF-----AHRRTWDAAERECRLQGAHLTSILSHEEQM--FVN 3217
Query: 700 FLTDQFSGQHWLWIGLNKRSPDLQGSWQWSD 730
+ G + WIGLN + + ++W+D
Sbjct: 3218 RV-----GHDYQWIGLNDKM--FEHDFRWTD 3241
Score = 47.0 bits (110), Expect = 2e-04
Identities = 32/112 (28%), Positives = 47/112 (41%), Gaps = 14/112 (12%)
Query: 1401 YEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPL-WVGLSSH 1459
++ Y + TW A C G HL S+ + Q+F V R G W+GL+
Sbjct: 3176 FQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMF----VNRVGHDYQWIGLNDK 3231
Query: 1460 DGSESSFEWSDGSTFDYIPWKGQ------TSPGNCVLL--DPKGTWKHEKCN 1503
E F W+DGST Y W+ ++ +CV++ G W CN
Sbjct: 3232 M-FEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCN 3282
Score = 46.6 bits (109), Expect = 2e-04
Identities = 33/135 (24%), Positives = 54/135 (40%), Gaps = 19/135 (14%)
Query: 1539 WIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRV 1598
W +++G CYK ++ A++ C A + SI +E FV+R+ +
Sbjct: 3173 WHKFQGQCYKYFAHRRTWDAAERECRLQ--GAHLTSILSHEEQMFVNRVGHDYQ------ 3224
Query: 1599 WLGLSQHSVDQSWSWLDGSEVTFVKWENKSK----SGVGRCSMLI-ASNETWKKVECEHG 1653
W+GL+ + + W DGS + + W S C ++I N W V C +
Sbjct: 3225 WIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYH 3284
Query: 1654 F------GRVVCKVP 1662
G V C P
Sbjct: 3285 LTYTCKKGTVACGQP 3299
Score = 34.7 bits (78), Expect = 0.82
Identities = 23/94 (24%), Positives = 35/94 (37%), Gaps = 11/94 (11%)
Query: 1248 WIPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNY 1307
W FQ CY + + T D +C+ +H+ SI +E FV +
Sbjct: 3173 WHKFQGQCYKYFAHRR-----TWDAAERECRLQG--AHLTSILSHEEQMFVNR----VGH 3221
Query: 1308 MASWVMLGITYRNKSLMWFDKTPLSYTHWRAGRP 1341
W+ L W D + L Y +WR +P
Sbjct: 3222 DYQWIGLNDKMFEHDFRWTDGSTLQYENWRPNQP 3255
>gi|29725633 regenerating islet-derived 1 alpha precursor [Homo
sapiens]
Length = 166
Score = 65.5 bits (158), Expect = 4e-10
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 6/123 (4%)
Query: 1542 YKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRVWLG 1601
Y+ +CY ++ ++ +A C ++ +S +VS+ + E FV+ L++E+ VW+G
Sbjct: 43 YRSYCYYFNEDRETWVDADLYC-QNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIG 101
Query: 1602 LSQHSVDQSWSWLDGSEVTFVKWENKSKSGV--GRCSMLIASN--ETWKKVECEHGFGRV 1657
L ++ W W GS V++ W + S V G C L +S + WK V CE F
Sbjct: 102 LHDPKKNRRWHWSSGSLVSYKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFS-F 160
Query: 1658 VCK 1660
VCK
Sbjct: 161 VCK 163
Score = 53.9 bits (128), Expect = 1e-06
Identities = 37/133 (27%), Positives = 59/133 (44%), Gaps = 8/133 (6%)
Query: 361 CDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSS-DLISIHSLADVEVVVTKLHNEDIKE 419
C G +CY + +W A C+ +S +L+S+ + A+ V + + +
Sbjct: 36 CPEGTNAYRSYCYYFNEDRETWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDD 95
Query: 420 -EVWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPN-CVSYLGELG--QWKVQ 475
VWIGL + + WS G+ V+ W P+ + P CVS G +WK
Sbjct: 96 FNVWIGLHDPKKNRRWHWSSGSLVSYKSWGIGAPS---SVNPGYCVSLTSSTGFQKWKDV 152
Query: 476 SCEEKLKYVCKRK 488
CE+K +VCK K
Sbjct: 153 PCEDKFSFVCKFK 165
Score = 53.5 bits (127), Expect = 2e-06
Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 10/120 (8%)
Query: 229 CYQFNTQTALSWKEAYVSCQNQGA-DLLSINSAAELTYLKE--KEGIAKIF--WIGLNQL 283
CY FN +W +A + CQN + +L+S+ + AE ++ KE F WIGL+
Sbjct: 47 CYYFNEDRE-TWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDP 105
Query: 284 YSARGWEWSDHKPLNFLNWDPDRPSAPTIGGSSCARMDAESGL--WQSFSCEAQLPYVCR 341
R W WS +++ +W PS ++ C + + +G W+ CE + +VC+
Sbjct: 106 KKNRRWHWSSGSLVSYKSWGIGAPS--SVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCK 163
Score = 36.2 bits (82), Expect = 0.28
Identities = 32/103 (31%), Positives = 44/103 (42%), Gaps = 14/103 (13%)
Query: 1123 TWHSAKRECLKSNM-QLVSITDPYQQAFLSVQALLHNS-----SLWIGLFSQDDELNFGW 1176
TW A C N LVS+ + AF V +L+ S ++WIGL + W
Sbjct: 56 TWVDADLYCQNMNSGNLVSVLTQAEGAF--VASLIKESGTDDFNVWIGLHDPKKNRRWHW 113
Query: 1177 SDGKRLHFSRW---AETNGQLEDCVVL-DTDGF--WKTVDCND 1213
S G + + W A ++ CV L + GF WK V C D
Sbjct: 114 SSGSLVSYKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCED 156
Score = 35.0 bits (79), Expect = 0.63
Identities = 32/136 (23%), Positives = 57/136 (41%), Gaps = 20/136 (14%)
Query: 501 CPPDEGWKRHGETCYKIYEDEVP------FGTNCN----LTITSRFEQEYLNDLMKKYDK 550
CP EG + CY ED + N N +++ ++ E ++ L+K+
Sbjct: 36 CP--EGTNAYRSYCYYFNEDRETWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGT 93
Query: 551 SLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFLEPAS--PGGCVAMSTGKSVGK 608
W GL D ++W++ V++ +W P+S PG CV++++ K
Sbjct: 94 DDFNV-WIGLHDPKKNRRWHWSSGS----LVSYKSWGIGAPSSVNPGYCVSLTSSTGFQK 148
Query: 609 WEVKDCRSFKALSICK 624
W+ C K +CK
Sbjct: 149 WKDVPCED-KFSFVCK 163
Score = 32.3 bits (72), Expect = 4.1
Identities = 35/140 (25%), Positives = 56/140 (40%), Gaps = 21/140 (15%)
Query: 1224 GNETEKEVKPVDSVKCPSPVLNTPWIPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPK 1283
G E + E+ P + CP +++ CY F N T D CQ +N
Sbjct: 22 GQEAQTEL-PQARISCPEGTN-----AYRSYCYYF----NEDRETWVD-ADLYCQNMN-S 69
Query: 1284 SHILSIRDEKENNFVLEQLLY-----FNYMASWVMLGITYRNKSLMWFDKTPLSYTHWRA 1338
+++S+ + E FV + FN W+ L +N+ W + +SY W
Sbjct: 70 GNLVSVLTQAEGAFVASLIKESGTDDFNV---WIGLHDPKKNRRWHWSSGSLVSYKSWGI 126
Query: 1339 GRPTIKNEKFLAGL-STDGF 1357
G P+ N + L S+ GF
Sbjct: 127 GAPSSVNPGYCVSLTSSTGF 146
>gi|10835248 regenerating islet-derived 1 beta precursor [Homo
sapiens]
Length = 166
Score = 64.7 bits (156), Expect = 7e-10
Identities = 35/123 (28%), Positives = 65/123 (52%), Gaps = 6/123 (4%)
Query: 1542 YKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRVWLG 1601
Y+ +CY ++ ++ +A C ++ +S +VS+ + E FV+ L++E++ VW+G
Sbjct: 43 YRSYCYYFNEDPETWVDADLYC-QNMNSGNLVSVLTQAEGAFVASLIKESSTDDSNVWIG 101
Query: 1602 LSQHSVDQSWSWLDGSEVTFVKWE--NKSKSGVGRCSMLIASN--ETWKKVECEHGFGRV 1657
L ++ W W GS V++ W+ + S + G C+ L + + + WK CE F
Sbjct: 102 LHDPKKNRRWHWSSGSLVSYKSWDTGSPSSANAGYCASLTSCSGFKKWKDESCEKKFS-F 160
Query: 1658 VCK 1660
VCK
Sbjct: 161 VCK 163
Score = 62.4 bits (150), Expect = 4e-09
Identities = 38/120 (31%), Positives = 60/120 (50%), Gaps = 10/120 (8%)
Query: 229 CYQFNTQTALSWKEAYVSCQNQGA-DLLSINSAAELTY----LKEKEGIAKIFWIGLNQL 283
CY FN +W +A + CQN + +L+S+ + AE + +KE WIGL+
Sbjct: 47 CYYFNEDPE-TWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESSTDDSNVWIGLHDP 105
Query: 284 YSARGWEWSDHKPLNFLNWDPDRPSAPTIGGSSCARMDAESGL--WQSFSCEAQLPYVCR 341
R W WS +++ +WD PS+ G CA + + SG W+ SCE + +VC+
Sbjct: 106 KKNRRWHWSSGSLVSYKSWDTGSPSSANAG--YCASLTSCSGFKKWKDESCEKKFSFVCK 163
Score = 57.8 bits (138), Expect = 9e-08
Identities = 34/130 (26%), Positives = 58/130 (44%), Gaps = 2/130 (1%)
Query: 361 CDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSS-DLISIHSLADVEVVVTKLHNEDIKE 419
C G +CY + +W A C+ +S +L+S+ + A+ V + + +
Sbjct: 36 CPEGTNAYRSYCYYFNEDPETWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESSTDD 95
Query: 420 E-VWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYLGELGQWKVQSCE 478
VWIGL + + WS G+ V+ WD P+ ++ +WK +SCE
Sbjct: 96 SNVWIGLHDPKKNRRWHWSSGSLVSYKSWDTGSPSSANAGYCASLTSCSGFKKWKDESCE 155
Query: 479 EKLKYVCKRK 488
+K +VCK K
Sbjct: 156 KKFSFVCKFK 165
Score = 35.0 bits (79), Expect = 0.63
Identities = 35/137 (25%), Positives = 57/137 (41%), Gaps = 15/137 (10%)
Query: 1224 GNETEKEVKPVDSVKCPSPVLNTPWIPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPK 1283
G E++ E+ P + CP +++ CY F N T D CQ +N
Sbjct: 22 GQESQTEL-PNPRISCPEGTN-----AYRSYCYYF----NEDPETWVD-ADLYCQNMN-S 69
Query: 1284 SHILSIRDEKENNFVLEQLLYFNYMAS--WVMLGITYRNKSLMWFDKTPLSYTHWRAGRP 1341
+++S+ + E FV + + S W+ L +N+ W + +SY W G P
Sbjct: 70 GNLVSVLTQAEGAFVASLIKESSTDDSNVWIGLHDPKKNRRWHWSSGSLVSYKSWDTGSP 129
Query: 1342 TIKNEKFLAGL-STDGF 1357
+ N + A L S GF
Sbjct: 130 SSANAGYCASLTSCSGF 146
Score = 33.5 bits (75), Expect = 1.8
Identities = 26/99 (26%), Positives = 42/99 (42%), Gaps = 10/99 (10%)
Query: 1123 TWHSAKRECLKSNM-QLVSITDPYQQAFLSV---QALLHNSSLWIGLFSQDDELNFGWSD 1178
TW A C N LVS+ + AF++ ++ +S++WIGL + WS
Sbjct: 56 TWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESSTDDSNVWIGLHDPKKNRRWHWSS 115
Query: 1179 GKRLHFSRW---AETNGQLEDCVVLDT-DGF--WKTVDC 1211
G + + W + ++ C L + GF WK C
Sbjct: 116 GSLVSYKSWDTGSPSSANAGYCASLTSCSGFKKWKDESC 154
>gi|18641360 collectin sub-family member 12 [Homo sapiens]
Length = 742
Score = 63.5 bits (153), Expect = 2e-09
Identities = 35/133 (26%), Positives = 64/133 (48%), Gaps = 7/133 (5%)
Query: 213 ENGCEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKEKEGI 272
+NGC +W+ CY F+ + + +++A + C+++ + L+ IN+ E ++K++
Sbjct: 604 DNGCPPHWKNFTD--KCYYFSVEKEI-FEDAKLFCEDKSSHLVFINTREEQQWIKKQMVG 660
Query: 273 AKIFWIGLNQLYSARGWEWSDHKPLNFLNWDPDRPSAPTIG---GSSCARMDAESGLWQS 329
+ WIGL W+W D ++ NW +P G G CA + +G W
Sbjct: 661 RESHWIGLTDSERENEWKWLDGTSPDYKNWKAGQPDNWGHGHGPGEDCAGL-IYAGQWND 719
Query: 330 FSCEAQLPYVCRK 342
F CE ++C K
Sbjct: 720 FQCEDVNNFICEK 732
Score = 54.3 bits (129), Expect = 1e-06
Identities = 35/133 (26%), Positives = 58/133 (43%), Gaps = 20/133 (15%)
Query: 1530 PAAKENGS--RWIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRL 1587
PA ++NG W + CY F +AK C D S+ +V I +E +++ +
Sbjct: 600 PAPEDNGCPPHWKNFTDKCYYFSVEKEIFEDAKLFCE--DKSSHLVFINTREEQQWIKKQ 657
Query: 1588 M--RENNNITMRVWLGLSQHSVDQSWSWLDGSEVTFVKWENKSKSGVGR-------CSML 1638
M RE++ W+GL+ + W WLDG+ + W+ G C+ L
Sbjct: 658 MVGRESH------WIGLTDSERENEWKWLDGTSPDYKNWKAGQPDNWGHGHGPGEDCAGL 711
Query: 1639 IASNETWKKVECE 1651
I + + W +CE
Sbjct: 712 IYAGQ-WNDFQCE 723
Score = 47.8 bits (112), Expect = 9e-05
Identities = 33/136 (24%), Positives = 57/136 (41%), Gaps = 7/136 (5%)
Query: 358 DTRCDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDI 417
D C W CY E ++ A C+ SS L+ I++ + + + ++
Sbjct: 604 DNGCPPHWKNFTDKCYYFSVEKEIFEDAKLFCEDKSSHLVFINTREEQQWIKKQMVG--- 660
Query: 418 KEEVWIGLKNINIPTLFQWSDGTEVTLTYWDENEP-NVPYNKTP--NCVSYLGELGQWKV 474
+E WIGL + ++W DGT W +P N + P +C + GQW
Sbjct: 661 RESHWIGLTDSERENEWKWLDGTSPDYKNWKAGQPDNWGHGHGPGEDCAGLI-YAGQWND 719
Query: 475 QSCEEKLKYVCKRKGE 490
CE+ ++C++ E
Sbjct: 720 FQCEDVNNFICEKDRE 735
Score = 45.4 bits (106), Expect = 5e-04
Identities = 39/144 (27%), Positives = 65/144 (45%), Gaps = 14/144 (9%)
Query: 1390 EYNTTLPQFMPYEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLE-DIVKRD 1448
E N P + + D Y +K + +A C HL ++ + Q +++ +V R+
Sbjct: 603 EDNGCPPHWKNFTDKCYYFSVEKEIFEDAKLFCEDKSSHLVFINTREEQQWIKKQMVGRE 662
Query: 1449 GFPLWVGLSSHDGSESSFEWSDGSTFDYIPWK-GQT-------SPG-NCVLLDPKGTWKH 1499
W+GL+ + E+ ++W DG++ DY WK GQ PG +C L G W
Sbjct: 663 SH--WIGLTDSE-RENEWKWLDGTSPDYKNWKAGQPDNWGHGHGPGEDCAGLIYAGQWND 719
Query: 1500 EKCNSVKDGAICYKPTKSKKLSRL 1523
+C V + IC K ++ S L
Sbjct: 720 FQCEDV-NNFICEKDRETVLSSAL 742
Score = 43.9 bits (102), Expect = 0.001
Identities = 39/145 (26%), Positives = 58/145 (40%), Gaps = 30/145 (20%)
Query: 605 SVGKWEVKDCRSFKALSICKKMSGPLGP----------------EEASPKPDDP-CPEGW 647
+VG+ V R L M GP GP E +P P+D CP W
Sbjct: 552 TVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTPAPEDNGCPPHW 611
Query: 648 QSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFLTDQFSG 707
++F CY V K +E+A+ FC+ +HL + +E ++ Q G
Sbjct: 612 KNFTDK--CYYFS-----VEKEIFEDAKLFCEDKSSHLVFIN----TREEQQWIKKQMVG 660
Query: 708 QHWLWIGLNKRSPDLQGSWQWSDRT 732
+ WIGL + + W+W D T
Sbjct: 661 RESHWIGLT--DSERENEWKWLDGT 683
Score = 40.0 bits (92), Expect = 0.020
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 9/94 (9%)
Query: 1248 WIPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNY 1307
W F + CY F + K ++ C+ + SH++ I +E ++ +Q++
Sbjct: 611 WKNFTDKCYYFSVEKEIF-----EDAKLFCE--DKSSHLVFINTREEQQWIKKQMV--GR 661
Query: 1308 MASWVMLGITYRNKSLMWFDKTPLSYTHWRAGRP 1341
+ W+ L + R W D T Y +W+AG+P
Sbjct: 662 ESHWIGLTDSERENEWKWLDGTSPDYKNWKAGQP 695
Score = 40.0 bits (92), Expect = 0.020
Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 9/98 (9%)
Query: 1124 WHSAKRECLKSNMQLVSITDPYQQAFLSVQALLHNSSLWIGLFSQDDELNFGWSDGKRLH 1183
+ AK C + LV I +Q ++ Q ++ S WIGL + E + W DG
Sbjct: 628 FEDAKLFCEDKSSHLVFINTREEQQWIKKQ-MVGRESHWIGLTDSERENEWKWLDGTSPD 686
Query: 1184 F--------SRWAETNGQLEDCVVLDTDGFWKTVDCND 1213
+ W +G EDC L G W C D
Sbjct: 687 YKNWKAGQPDNWGHGHGPGEDCAGLIYAGQWNDFQCED 724
Score = 33.9 bits (76), Expect = 1.4
Identities = 35/147 (23%), Positives = 58/147 (39%), Gaps = 31/147 (21%)
Query: 495 ASSDKMCPPDEGWKRHGETCY------KIYEDEVPFGTNCN---LTITSRFEQEYLNDLM 545
A D CPP WK + CY +I+ED F + + + I +R EQ+++ M
Sbjct: 601 APEDNGCPPH--WKNFTDKCYYFSVEKEIFEDAKLFCEDKSSHLVFINTREEQQWIKKQM 658
Query: 546 KKYDKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFLEPASPG-------GCV 598
R+ W GL D + E+ W + + NW +P + G C
Sbjct: 659 VG-----RESHWIGLTDSERENEWKWLD----GTSPDYKNWKAGQPDNWGHGHGPGEDCA 709
Query: 599 AMSTGKSVGKWEVKDCRSFKALSICKK 625
+ ++ +D +F IC+K
Sbjct: 710 GLIYAGQWNDFQCEDVNNF----ICEK 732
Score = 32.3 bits (72), Expect = 4.1
Identities = 35/146 (23%), Positives = 56/146 (38%), Gaps = 19/146 (13%)
Query: 951 CSEQWIPFQNKCFLKIKPVSLTFSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATL 1010
C W F +KC+ + F A C L + ++ EQ +I + E+
Sbjct: 607 CPPHWKNFTDKCYYFSVEKEI-FEDAKLFCEDKSSHLVFINTREEQQWIKKQMVGRESH- 664
Query: 1011 WIGLRWTAYEKINKWTDNRELTYSNFHPLLVSGRLRIPENFFEEES-RYHCALILNLQKS 1069
WIGL + E KW D Y N+ + P+N+ CA ++
Sbjct: 665 WIGLTDSERENEWKWLDGTSPDYKNW-------KAGQPDNWGHGHGPGEDCAGLI----- 712
Query: 1070 PFTGTWNFTSCSE-RHFVSLCQKYSE 1094
+ G WN C + +F+ C+K E
Sbjct: 713 -YAGQWNDFQCEDVNNFI--CEKDRE 735
>gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]
Length = 707
Score = 63.2 bits (152), Expect = 2e-09
Identities = 26/58 (44%), Positives = 36/58 (62%), Gaps = 1/58 (1%)
Query: 153 PYHEIYTRDGNSYGRPCEFPFLIDGTWHHDCILDEDHSG-PWCATTLNYEYDRKWGIC 209
P +YT+DGN+ G+PC+FPF+ G + C D G WCATT NY+ D+ +G C
Sbjct: 272 PSERLYTQDGNADGKPCQFPFIFQGQSYSACTTDGRSDGYRWCATTANYDRDKLFGFC 329
Score = 53.9 bits (128), Expect = 1e-06
Identities = 23/52 (44%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
Query: 159 TRDGNSYGRPCEFPFLIDGTWHHDCILDEDHSG-PWCATTLNYEYDRKWGIC 209
TR GN+ G C FPF+ +G + C D G PWC+TT NY+ D ++G C
Sbjct: 220 TRFGNADGAACHFPFIFEGRSYSACTTDGRSDGLPWCSTTANYDTDDRFGFC 271
Score = 49.3 bits (116), Expect = 3e-05
Identities = 24/55 (43%), Positives = 30/55 (54%), Gaps = 3/55 (5%)
Query: 162 GNSYGRPCEFPFLIDGTWHHDCILDEDHSGP-WCATTLNYEYDRKWGICLKPENG 215
GNS G C FPF G + C + G WCATT N++ D+KWG C P+ G
Sbjct: 340 GNSAGELCVFPFTFLGKEYSTCTSEGRGDGRLWCATTSNFDSDKKWGFC--PDQG 392
>gi|226823233 regenerating islet-derived family, member 4 isoform 1
[Homo sapiens]
Length = 158
Score = 62.8 bits (151), Expect = 3e-09
Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 11/118 (9%)
Query: 1539 WIQYKGHCYKSDQALHSFSEAKKLCSKHD---HSATIVSIKDEDE-NKFVSRLMRENNNI 1594
W +K +CY + L ++S+A+ C + H A+I+S+K+ +++S R
Sbjct: 34 WFYHKSNCYGYFRKLRNWSDAELECQSYGNGAHLASILSLKEASTIAEYISGYQR----- 88
Query: 1595 TMRVWLGLSQHSVDQSWSWLDGSEVTFVKWENKSKSGVGRCSMLIASNE--TWKKVEC 1650
+ +W+GL Q W W+DG+ + W KS G C+ + ++N TW EC
Sbjct: 89 SQPIWIGLHDPQKRQQWQWIDGAMYLYRSWSGKSMGGNKHCAEMSSNNNFLTWSSNEC 146
Score = 49.7 bits (117), Expect = 2e-05
Identities = 29/128 (22%), Positives = 52/128 (40%), Gaps = 4/128 (3%)
Query: 361 CDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSD--LISIHSLADVEVVVTKLHNEDIK 418
C GW + CY + +W A +C+++ + L SI SL + + +
Sbjct: 30 CAPGWFYHKSNCYGYFRKLRNWSDAELECQSYGNGAHLASILSLKEASTIAEYISGYQRS 89
Query: 419 EEVWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYLGELGQWKVQSCE 478
+ +WIGL + +QW DG W + ++ NK +S W C
Sbjct: 90 QPIWIGLHDPQKRQQWQWIDGAMYLYRSW--SGKSMGGNKHCAEMSSNNNFLTWSSNECN 147
Query: 479 EKLKYVCK 486
++ ++CK
Sbjct: 148 KRQHFLCK 155
Score = 48.5 bits (114), Expect = 6e-05
Identities = 38/120 (31%), Positives = 53/120 (44%), Gaps = 18/120 (15%)
Query: 615 RSFKALSI--CKKMSGPLGPEEASPKPDDPCPEGWQSFPASLSCYKVFHAERIVRKRNWE 672
RS + L + C +G LG P C GW F +CY F + RNW
Sbjct: 4 RSMRLLLLLSCLAKTGVLGDIIMRPS----CAPGW--FYHKSNCYGYFR-----KLRNWS 52
Query: 673 EAERFCQAL--GAHLSSFSHVDEIKEFLHFLTDQFSGQHWLWIGLNKRSPDLQGSWQWSD 730
+AE CQ+ GAHL+S + E +++ Q +WIGL+ P + WQW D
Sbjct: 53 DAELECQSYGNGAHLASILSLKEASTIAEYISGYQRSQP-IWIGLH--DPQKRQQWQWID 109
Score = 48.1 bits (113), Expect = 7e-05
Identities = 32/129 (24%), Positives = 57/129 (44%), Gaps = 12/129 (9%)
Query: 1396 PQFMPYEDGIYSVIQKKVTWYEALNMCSQ--SGGHLASVHNQNGQLFLEDIVK--RDGFP 1451
P + ++ Y +K W +A C +G HLAS+ + + + + + P
Sbjct: 32 PGWFYHKSNCYGYFRKLRNWSDAELECQSYGNGAHLASILSLKEASTIAEYISGYQRSQP 91
Query: 1452 LWVGLSSHDGSE-SSFEWSDGSTFDYIPWKGQTSPGN--CVLLDPKG---TWKHEKCNSV 1505
+W+GL HD + ++W DG+ + Y W G++ GN C + TW +CN
Sbjct: 92 IWIGL--HDPQKRQQWQWIDGAMYLYRSWSGKSMGGNKHCAEMSSNNNFLTWSSNECNKR 149
Query: 1506 KDGAICYKP 1514
+ Y+P
Sbjct: 150 QHFLCKYRP 158
Score = 47.8 bits (112), Expect = 9e-05
Identities = 33/142 (23%), Positives = 64/142 (45%), Gaps = 18/142 (12%)
Query: 208 ICLKPENGCEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQG-----ADLLSINSAAE 262
I ++P C W ++ +CY + + +W +A + CQ+ G A +LS+ A+
Sbjct: 24 IIMRPS--CAPGWFYHKS--NCYGYFRKLR-NWSDAELECQSYGNGAHLASILSLKEAST 78
Query: 263 LTYLKEKEGIAKIFWIGLNQLYSARGWEWSDHKPLNFLNWDPDRPSAPTIGGSS-CARMD 321
+ ++ WIGL+ + W+W D + +W S ++GG+ CA M
Sbjct: 79 IAEYISGYQRSQPIWIGLHDPQKRQQWQWIDGAMYLYRSW-----SGKSMGGNKHCAEMS 133
Query: 322 AESGL--WQSFSCEAQLPYVCR 341
+ + W S C + ++C+
Sbjct: 134 SNNNFLTWSSNECNKRQHFLCK 155
Score = 35.8 bits (81), Expect = 0.37
Identities = 24/112 (21%), Positives = 45/112 (40%), Gaps = 8/112 (7%)
Query: 1112 NNLYKIIPKTLTWHSAKRECLK--SNMQLVSITDPYQQAFLS--VQALLHNSSLWIGLFS 1167
+N Y K W A+ EC + L SI + + ++ + + +WIGL
Sbjct: 39 SNCYGYFRKLRNWSDAELECQSYGNGAHLASILSLKEASTIAEYISGYQRSQPIWIGLHD 98
Query: 1168 QDDELNFGWSDGKRLHFSRWA-ETNGQLEDCVVLDTDG---FWKTVDCNDNQ 1215
+ W DG + W+ ++ G + C + ++ W + +CN Q
Sbjct: 99 PQKRQQWQWIDGAMYLYRSWSGKSMGGNKHCAEMSSNNNFLTWSSNECNKRQ 150
>gi|14042980 regenerating islet-derived family, member 4 isoform 1
[Homo sapiens]
Length = 158
Score = 62.8 bits (151), Expect = 3e-09
Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 11/118 (9%)
Query: 1539 WIQYKGHCYKSDQALHSFSEAKKLCSKHD---HSATIVSIKDEDE-NKFVSRLMRENNNI 1594
W +K +CY + L ++S+A+ C + H A+I+S+K+ +++S R
Sbjct: 34 WFYHKSNCYGYFRKLRNWSDAELECQSYGNGAHLASILSLKEASTIAEYISGYQR----- 88
Query: 1595 TMRVWLGLSQHSVDQSWSWLDGSEVTFVKWENKSKSGVGRCSMLIASNE--TWKKVEC 1650
+ +W+GL Q W W+DG+ + W KS G C+ + ++N TW EC
Sbjct: 89 SQPIWIGLHDPQKRQQWQWIDGAMYLYRSWSGKSMGGNKHCAEMSSNNNFLTWSSNEC 146
Score = 49.7 bits (117), Expect = 2e-05
Identities = 29/128 (22%), Positives = 52/128 (40%), Gaps = 4/128 (3%)
Query: 361 CDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSD--LISIHSLADVEVVVTKLHNEDIK 418
C GW + CY + +W A +C+++ + L SI SL + + +
Sbjct: 30 CAPGWFYHKSNCYGYFRKLRNWSDAELECQSYGNGAHLASILSLKEASTIAEYISGYQRS 89
Query: 419 EEVWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYLGELGQWKVQSCE 478
+ +WIGL + +QW DG W + ++ NK +S W C
Sbjct: 90 QPIWIGLHDPQKRQQWQWIDGAMYLYRSW--SGKSMGGNKHCAEMSSNNNFLTWSSNECN 147
Query: 479 EKLKYVCK 486
++ ++CK
Sbjct: 148 KRQHFLCK 155
Score = 48.5 bits (114), Expect = 6e-05
Identities = 38/120 (31%), Positives = 53/120 (44%), Gaps = 18/120 (15%)
Query: 615 RSFKALSI--CKKMSGPLGPEEASPKPDDPCPEGWQSFPASLSCYKVFHAERIVRKRNWE 672
RS + L + C +G LG P C GW F +CY F + RNW
Sbjct: 4 RSMRLLLLLSCLAKTGVLGDIIMRPS----CAPGW--FYHKSNCYGYFR-----KLRNWS 52
Query: 673 EAERFCQAL--GAHLSSFSHVDEIKEFLHFLTDQFSGQHWLWIGLNKRSPDLQGSWQWSD 730
+AE CQ+ GAHL+S + E +++ Q +WIGL+ P + WQW D
Sbjct: 53 DAELECQSYGNGAHLASILSLKEASTIAEYISGYQRSQP-IWIGLH--DPQKRQQWQWID 109
Score = 48.1 bits (113), Expect = 7e-05
Identities = 32/129 (24%), Positives = 57/129 (44%), Gaps = 12/129 (9%)
Query: 1396 PQFMPYEDGIYSVIQKKVTWYEALNMCSQ--SGGHLASVHNQNGQLFLEDIVK--RDGFP 1451
P + ++ Y +K W +A C +G HLAS+ + + + + + P
Sbjct: 32 PGWFYHKSNCYGYFRKLRNWSDAELECQSYGNGAHLASILSLKEASTIAEYISGYQRSQP 91
Query: 1452 LWVGLSSHDGSE-SSFEWSDGSTFDYIPWKGQTSPGN--CVLLDPKG---TWKHEKCNSV 1505
+W+GL HD + ++W DG+ + Y W G++ GN C + TW +CN
Sbjct: 92 IWIGL--HDPQKRQQWQWIDGAMYLYRSWSGKSMGGNKHCAEMSSNNNFLTWSSNECNKR 149
Query: 1506 KDGAICYKP 1514
+ Y+P
Sbjct: 150 QHFLCKYRP 158
Score = 47.8 bits (112), Expect = 9e-05
Identities = 33/142 (23%), Positives = 64/142 (45%), Gaps = 18/142 (12%)
Query: 208 ICLKPENGCEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQG-----ADLLSINSAAE 262
I ++P C W ++ +CY + + +W +A + CQ+ G A +LS+ A+
Sbjct: 24 IIMRPS--CAPGWFYHKS--NCYGYFRKLR-NWSDAELECQSYGNGAHLASILSLKEAST 78
Query: 263 LTYLKEKEGIAKIFWIGLNQLYSARGWEWSDHKPLNFLNWDPDRPSAPTIGGSS-CARMD 321
+ ++ WIGL+ + W+W D + +W S ++GG+ CA M
Sbjct: 79 IAEYISGYQRSQPIWIGLHDPQKRQQWQWIDGAMYLYRSW-----SGKSMGGNKHCAEMS 133
Query: 322 AESGL--WQSFSCEAQLPYVCR 341
+ + W S C + ++C+
Sbjct: 134 SNNNFLTWSSNECNKRQHFLCK 155
Score = 35.8 bits (81), Expect = 0.37
Identities = 24/112 (21%), Positives = 45/112 (40%), Gaps = 8/112 (7%)
Query: 1112 NNLYKIIPKTLTWHSAKRECLK--SNMQLVSITDPYQQAFLS--VQALLHNSSLWIGLFS 1167
+N Y K W A+ EC + L SI + + ++ + + +WIGL
Sbjct: 39 SNCYGYFRKLRNWSDAELECQSYGNGAHLASILSLKEASTIAEYISGYQRSQPIWIGLHD 98
Query: 1168 QDDELNFGWSDGKRLHFSRWA-ETNGQLEDCVVLDTDG---FWKTVDCNDNQ 1215
+ W DG + W+ ++ G + C + ++ W + +CN Q
Sbjct: 99 PQKRQQWQWIDGAMYLYRSWSGKSMGGNKHCAEMSSNNNFLTWSSNECNKRQ 150
>gi|38348296 C-type lectin domain family 4, member G [Homo sapiens]
Length = 293
Score = 62.0 bits (149), Expect = 5e-09
Identities = 38/124 (30%), Positives = 56/124 (45%), Gaps = 11/124 (8%)
Query: 1398 FMPYEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLS 1457
++ +E Y K TW A + C+ + HL V + Q FL + G+ W+GL
Sbjct: 169 WLSFEGSCYFFSVPKTTWAAAQDHCADASAHLVIVGGLDEQGFLTRNTRGRGY--WLGLR 226
Query: 1458 S--HDGSESSFEWSDGSTFDYIPWKGQTSPG------NCVLLDPKGTWKHEKCNSVKDGA 1509
+ H G ++W DG + + W Q P NCV++ G W C+S KDG
Sbjct: 227 AVRHLGKVQGYQWVDGVSLSFSHW-NQGEPNDAWGRENCVMMLHTGLWNDAPCDSEKDGW 285
Query: 1510 ICYK 1513
IC K
Sbjct: 286 ICEK 289
Score = 57.4 bits (137), Expect = 1e-07
Identities = 37/152 (24%), Positives = 64/152 (42%), Gaps = 10/152 (6%)
Query: 341 RKPLNNTVELTDVWTYSDTRCDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIH 400
R L +E + S C WL G CY +W A C S+ L+ +
Sbjct: 145 RTELFRALEAVRLQNNSCEPCPTSWLSFEGSCYFFSVPKTTWAAAQDHCADASAHLVIVG 204
Query: 401 SLADVEVVVTKLHNEDIKEEVWIGLK---NINIPTLFQWSDGTEVTLTYWDENEPNVPYN 457
L + + W+GL+ ++ +QW DG ++ ++W++ EPN +
Sbjct: 205 GLDEQGFLTRNTRGRGY----WLGLRAVRHLGKVQGYQWVDGVSLSFSHWNQGEPNDAWG 260
Query: 458 KTPNCVSYLGELGQWKVQSCE-EKLKYVCKRK 488
+ NCV L G W C+ EK ++C+++
Sbjct: 261 R-ENCVMML-HTGLWNDAPCDSEKDGWICEKR 290
Score = 52.0 bits (123), Expect = 5e-06
Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 10/134 (7%)
Query: 216 CEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKEKEGIAKI 275
C +W E GSCY F+ +W A C + A L+ + E +L +
Sbjct: 165 CPTSWLSFE--GSCYFFSVPKT-TWAAAQDHCADASAHLVIVGGLDEQGFLTRNTR-GRG 220
Query: 276 FWIGLN---QLYSARGWEWSDHKPLNFLNWDPDRPSAPTIGGSSCARMDAESGLWQSFSC 332
+W+GL L +G++W D L+F +W+ P+ G +C M +GLW C
Sbjct: 221 YWLGLRAVRHLGKVQGYQWVDGVSLSFSHWNQGEPN-DAWGRENCVMM-LHTGLWNDAPC 278
Query: 333 EAQLP-YVCRKPLN 345
+++ ++C K N
Sbjct: 279 DSEKDGWICEKRHN 292
Score = 47.8 bits (112), Expect = 9e-05
Identities = 33/110 (30%), Positives = 49/110 (44%), Gaps = 10/110 (9%)
Query: 1118 IPKTLTWHSAKRECLKSNMQLVSITDPYQQAFLSVQALLHNSSLWIGLFSQ---DDELNF 1174
+PKT TW +A+ C ++ LV + +Q FL+ W+GL + +
Sbjct: 181 VPKT-TWAAAQDHCADASAHLVIVGGLDEQGFLTRNT--RGRGYWLGLRAVRHLGKVQGY 237
Query: 1175 GWSDGKRLHFSRW--AETNGQL--EDCVVLDTDGFWKTVDCNDNQPGAIC 1220
W DG L FS W E N E+CV++ G W C+ + G IC
Sbjct: 238 QWVDGVSLSFSHWNQGEPNDAWGRENCVMMLHTGLWNDAPCDSEKDGWIC 287
Score = 42.4 bits (98), Expect = 0.004
Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 14/128 (10%)
Query: 1539 WIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRV 1598
W+ ++G CY +++ A+ C+ D SA +V + DE F++R R
Sbjct: 169 WLSFEGSCYFFSVPKTTWAAAQDHCA--DASAHLVIVGGLDEQGFLTRNTRGRG-----Y 221
Query: 1599 WLGLS--QH-SVDQSWSWLDGSEVTFVKW---ENKSKSGVGRCSMLIASNETWKKVECEH 1652
WLGL +H Q + W+DG ++F W E G C M++ + W C+
Sbjct: 222 WLGLRAVRHLGKVQGYQWVDGVSLSFSHWNQGEPNDAWGRENCVMMLHTG-LWNDAPCDS 280
Query: 1653 GFGRVVCK 1660
+C+
Sbjct: 281 EKDGWICE 288
Score = 39.3 bits (90), Expect = 0.033
Identities = 32/96 (33%), Positives = 43/96 (44%), Gaps = 13/96 (13%)
Query: 641 DPCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHF 700
+PCP W SF SCY F + V K W A+ C AHL +DE F
Sbjct: 163 EPCPTSWLSFEG--SCY--FFS---VPKTTWAAAQDHCADASAHLVIVGGLDE----QGF 211
Query: 701 LTDQFSGQ-HWLWIGLNKRSPDLQGSWQWSDRTPVS 735
LT G+ +WL + + +QG +QW D +S
Sbjct: 212 LTRNTRGRGYWLGLRAVRHLGKVQG-YQWVDGVSLS 246
Score = 36.6 bits (83), Expect = 0.22
Identities = 22/96 (22%), Positives = 36/96 (37%), Gaps = 7/96 (7%)
Query: 1246 TPWIPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYF 1305
T W+ F+ CY F + K A QD + +H++ + E F+
Sbjct: 167 TSWLSFEGSCYFFSVPKTT-WAAAQDHC------ADASAHLVIVGGLDEQGFLTRNTRGR 219
Query: 1306 NYMASWVMLGITYRNKSLMWFDKTPLSYTHWRAGRP 1341
Y + + + W D LS++HW G P
Sbjct: 220 GYWLGLRAVRHLGKVQGYQWVDGVSLSFSHWNQGEP 255
>gi|33667103 C-type lectin, superfamily member 14 isoform 1 [Homo
sapiens]
Length = 316
Score = 62.0 bits (149), Expect = 5e-09
Identities = 44/138 (31%), Positives = 63/138 (45%), Gaps = 13/138 (9%)
Query: 216 CEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKEKEGIAKI 275
C NW +++ SCY F+ + +SW EA CQ + A L+ INS E ++++ G A
Sbjct: 181 CPVNWVEHQD--SCYWFS-HSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYLGSA-Y 236
Query: 276 FWIGLNQLYSARGWEWSD--HKPLNFLNWDPDRP----SAPTIGGSSCARMDAESGLWQS 329
W+GL+ A W+W D F NW P +P GG CA + G W
Sbjct: 237 TWMGLSDPEGA--WKWVDGTDYATGFQNWKPGQPDDWQGHGLGGGEDCAHFHPD-GRWND 293
Query: 330 FSCEAQLPYVCRKPLNNT 347
C+ +VC L T
Sbjct: 294 DVCQRPYHWVCEAGLGQT 311
Score = 49.3 bits (116), Expect = 3e-05
Identities = 42/163 (25%), Positives = 64/163 (39%), Gaps = 40/163 (24%)
Query: 643 CPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFLT 702
CP W S CY H+ +W EAE++CQ AHL + +E
Sbjct: 181 CPVNWVEHQDS--CYWFSHSGM-----SWAEAEKYCQLKNAHLVVINSREE-----QNFV 228
Query: 703 DQFSGQHWLWIGLNKRSPDLQGSWQWSDRTPVSTII------MPNEFQQD--YDIRDCAA 754
++ G + W+GL+ D +G+W+W D T +T P+++Q DCA
Sbjct: 229 QKYLGSAYTWMGLS----DPEGAWKWVDGTDYATGFQNWKPGQPDDWQGHGLGGGEDCA- 283
Query: 755 VKVFHRPWRRGWHFYDDREFIYLRPFACDTKLEWVCQIPKGRT 797
HF+ D + C WVC+ G+T
Sbjct: 284 ------------HFHPDGRW---NDDVCQRPYHWVCEAGLGQT 311
Score = 43.1 bits (100), Expect = 0.002
Identities = 24/89 (26%), Positives = 45/89 (50%), Gaps = 11/89 (12%)
Query: 1539 WIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRV 1598
W++++ CY + S++EA+K C +A +V I +E FV + + +
Sbjct: 185 WVEHQDSCYWFSHSGMSWAEAEKYCQL--KNAHLVVINSREEQNFVQKYLG-----SAYT 237
Query: 1599 WLGLSQHSVDQSWSWLDGSEVT--FVKWE 1625
W+GLS + +W W+DG++ F W+
Sbjct: 238 WMGLS--DPEGAWKWVDGTDYATGFQNWK 264
Score = 42.0 bits (97), Expect = 0.005
Identities = 27/117 (23%), Positives = 52/117 (44%), Gaps = 17/117 (14%)
Query: 1398 FMPYEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLS 1457
++ ++D Y ++W EA C HL ++++ Q F++ + W+GLS
Sbjct: 185 WVEHQDSCYWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYL--GSAYTWMGLS 242
Query: 1458 SHDGSESSFEWSDGSTF-----DYIP-----WKGQTSPG--NCVLLDPKGTWKHEKC 1502
+G +++W DG+ + ++ P W+G G +C P G W + C
Sbjct: 243 DPEG---AWKWVDGTDYATGFQNWKPGQPDDWQGHGLGGGEDCAHFHPDGRWNDDVC 296
Score = 40.4 bits (93), Expect = 0.015
Identities = 29/134 (21%), Positives = 55/134 (41%), Gaps = 13/134 (9%)
Query: 359 TRCDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIK 418
T C W+ + CY + SW +A C+ ++ L+ I+S + V L +
Sbjct: 179 TCCPVNWVEHQDSCYWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYLGS---- 234
Query: 419 EEVWIGLKNINIPTLFQWSDGTEVTLTY--WDENEPN----VPYNKTPNCVSYLGELGQW 472
W+GL + ++W DGT+ + W +P+ +C + + G+W
Sbjct: 235 AYTWMGLSDPE--GAWKWVDGTDYATGFQNWKPGQPDDWQGHGLGGGEDCAHFHPD-GRW 291
Query: 473 KVQSCEEKLKYVCK 486
C+ +VC+
Sbjct: 292 NDDVCQRPYHWVCE 305
>gi|53832016 C-type lectin, superfamily member 14 isoform 2 [Homo
sapiens]
Length = 292
Score = 62.0 bits (149), Expect = 5e-09
Identities = 44/138 (31%), Positives = 63/138 (45%), Gaps = 13/138 (9%)
Query: 216 CEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKEKEGIAKI 275
C NW +++ SCY F+ + +SW EA CQ + A L+ INS E ++++ G A
Sbjct: 157 CPVNWVEHQD--SCYWFS-HSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYLGSA-Y 212
Query: 276 FWIGLNQLYSARGWEWSD--HKPLNFLNWDPDRP----SAPTIGGSSCARMDAESGLWQS 329
W+GL+ A W+W D F NW P +P GG CA + G W
Sbjct: 213 TWMGLSDPEGA--WKWVDGTDYATGFQNWKPGQPDDWQGHGLGGGEDCAHFHPD-GRWND 269
Query: 330 FSCEAQLPYVCRKPLNNT 347
C+ +VC L T
Sbjct: 270 DVCQRPYHWVCEAGLGQT 287
Score = 49.7 bits (117), Expect = 2e-05
Identities = 46/173 (26%), Positives = 69/173 (39%), Gaps = 41/173 (23%)
Query: 633 EEASPKPDDPCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVD 692
EEAS + CP W S CY H+ +W EAE++CQ AHL + +
Sbjct: 148 EEASTE-GTCCPVNWVEHQDS--CYWFSHSGM-----SWAEAEKYCQLKNAHLVVINSRE 199
Query: 693 EIKEFLHFLTDQFSGQHWLWIGLNKRSPDLQGSWQWSDRTPVSTII------MPNEFQQD 746
E ++ G + W+GL+ D +G+W+W D T +T P+++Q
Sbjct: 200 E-----QNFVQKYLGSAYTWMGLS----DPEGAWKWVDGTDYATGFQNWKPGQPDDWQGH 250
Query: 747 --YDIRDCAAVKVFHRPWRRGWHFYDDREFIYLRPFACDTKLEWVCQIPKGRT 797
DCA HF+ D + C WVC+ G+T
Sbjct: 251 GLGGGEDCA-------------HFHPDGRW---NDDVCQRPYHWVCEAGLGQT 287
Score = 43.1 bits (100), Expect = 0.002
Identities = 24/89 (26%), Positives = 45/89 (50%), Gaps = 11/89 (12%)
Query: 1539 WIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRV 1598
W++++ CY + S++EA+K C +A +V I +E FV + + +
Sbjct: 161 WVEHQDSCYWFSHSGMSWAEAEKYCQL--KNAHLVVINSREEQNFVQKYLG-----SAYT 213
Query: 1599 WLGLSQHSVDQSWSWLDGSEVT--FVKWE 1625
W+GLS + +W W+DG++ F W+
Sbjct: 214 WMGLS--DPEGAWKWVDGTDYATGFQNWK 240
Score = 42.4 bits (98), Expect = 0.004
Identities = 32/142 (22%), Positives = 60/142 (42%), Gaps = 22/142 (15%)
Query: 1378 LACKIEMVDYKEEYNTTLPQFMP-----YEDGIYSVIQKKVTWYEALNMCSQSGGHLASV 1432
L C++ ++ E +T P ++D Y ++W EA C HL +
Sbjct: 136 LTCQVATLNNNGEEASTEGTCCPVNWVEHQDSCYWFSHSGMSWAEAEKYCQLKNAHLVVI 195
Query: 1433 HNQNGQLFLEDIVKRDGFPLWVGLSSHDGSESSFEWSDGSTF-----DYIP-----WKGQ 1482
+++ Q F++ + W+GLS +G +++W DG+ + ++ P W+G
Sbjct: 196 NSREEQNFVQKYL--GSAYTWMGLSDPEG---AWKWVDGTDYATGFQNWKPGQPDDWQGH 250
Query: 1483 TSPG--NCVLLDPKGTWKHEKC 1502
G +C P G W + C
Sbjct: 251 GLGGGEDCAHFHPDGRWNDDVC 272
Score = 40.4 bits (93), Expect = 0.015
Identities = 29/134 (21%), Positives = 55/134 (41%), Gaps = 13/134 (9%)
Query: 359 TRCDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIK 418
T C W+ + CY + SW +A C+ ++ L+ I+S + V L +
Sbjct: 155 TCCPVNWVEHQDSCYWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYLGS---- 210
Query: 419 EEVWIGLKNINIPTLFQWSDGTEVTLTY--WDENEPN----VPYNKTPNCVSYLGELGQW 472
W+GL + ++W DGT+ + W +P+ +C + + G+W
Sbjct: 211 AYTWMGLSDPE--GAWKWVDGTDYATGFQNWKPGQPDDWQGHGLGGGEDCAHFHPD-GRW 267
Query: 473 KVQSCEEKLKYVCK 486
C+ +VC+
Sbjct: 268 NDDVCQRPYHWVCE 281
>gi|20149533 Fc fragment of IgE, low affinity II, receptor for (CD23A)
[Homo sapiens]
Length = 321
Score = 60.1 bits (144), Expect = 2e-08
Identities = 50/157 (31%), Positives = 65/157 (41%), Gaps = 14/157 (8%)
Query: 1108 VKYLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITDPYQQAFLSVQALLHNSSLWIGLFS 1167
+ + Y T W A+ C QLVSI P +Q FL+ A H S WIGL +
Sbjct: 168 INFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHAS-HTGS-WIGLRN 225
Query: 1168 QDDELNFGWSDGKRLHFSRWA----ETNGQLEDCVVLDTDGFWKTVDCNDNQPG------ 1217
D + F W DG + +S WA + Q EDCV++ G W C D + G
Sbjct: 226 LDLKGEFIWVDGSHVDYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFC-DRKLGAWVCDR 284
Query: 1218 -AICYYSGNETEKEVKPVDSVKCPSPVLNTPWIPFQN 1253
A C +E E DS P L TP P +
Sbjct: 285 LATCTPPASEGSAESMGPDSRPDPDGRLPTPSAPLHS 321
Score = 58.5 bits (140), Expect = 5e-08
Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 7/128 (5%)
Query: 361 CDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEE 420
C W+ CY + W A C L+SIHS + + + +
Sbjct: 163 CPEKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGS--- 219
Query: 421 VWIGLKNINIPTLFQWSDGTEVTLTYWDENEPNVPYNKTPNCVSYLGELGQWKVQSCEEK 480
WIGL+N+++ F W DG+ V + W EP ++ +CV G G+W C+ K
Sbjct: 220 -WIGLRNLDLKGEFIWVDGSHVDYSNWAPGEP-TSRSQGEDCVMMRGS-GRWNDAFCDRK 276
Query: 481 L-KYVCKR 487
L +VC R
Sbjct: 277 LGAWVCDR 284
Score = 53.5 bits (127), Expect = 2e-06
Identities = 38/128 (29%), Positives = 56/128 (43%), Gaps = 7/128 (5%)
Query: 214 NGCEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKEKEGIA 273
N C + W ++ CY F T W A +C + L+SI+S E +L K
Sbjct: 161 NTCPEKWINFQR--KCYYFGKGTK-QWVHARYACDDMEGQLVSIHSPEEQDFLT-KHASH 216
Query: 274 KIFWIGLNQLYSARGWEWSDHKPLNFLNWDPDRPSAPTIGGSSCARMDAESGLWQSFSCE 333
WIGL L + W D +++ NW P P++ + G C M SG W C+
Sbjct: 217 TGSWIGLRNLDLKGEFIWVDGSHVDYSNWAPGEPTSRS-QGEDCVMMRG-SGRWNDAFCD 274
Query: 334 AQL-PYVC 340
+L +VC
Sbjct: 275 RKLGAWVC 282
Score = 50.4 bits (119), Expect = 1e-05
Identities = 32/125 (25%), Positives = 52/125 (41%), Gaps = 11/125 (8%)
Query: 1538 RWIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMR 1597
+WI ++ CY + + A+ C D +VSI +E F+++ +
Sbjct: 166 KWINFQRKCYYFGKGTKQWVHARYACD--DMEGQLVSIHSPEEQDFLTKHASHTGS---- 219
Query: 1598 VWLGLSQHSVDQSWSWLDGSEVTFVKW---ENKSKSGVGRCSMLIASNETWKKVECEHGF 1654
W+GL + + W+DGS V + W E S+S C M+ S W C+
Sbjct: 220 -WIGLRNLDLKGEFIWVDGSHVDYSNWAPGEPTSRSQGEDCVMMRGSGR-WNDAFCDRKL 277
Query: 1655 GRVVC 1659
G VC
Sbjct: 278 GAWVC 282
Score = 48.5 bits (114), Expect = 6e-05
Identities = 32/125 (25%), Positives = 50/125 (40%), Gaps = 8/125 (6%)
Query: 1392 NTTLPQFMPYEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFP 1451
NT +++ ++ Y + W A C G L S+H+ Q FL G
Sbjct: 161 NTCPEKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGS- 219
Query: 1452 LWVGLSSHDGSESSFEWSDGSTFDYIPW-----KGQTSPGNCVLLDPKGTWKHEKCNSVK 1506
W+GL + D + F W DGS DY W ++ +CV++ G W C+
Sbjct: 220 -WIGLRNLD-LKGEFIWVDGSHVDYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKL 277
Query: 1507 DGAIC 1511
+C
Sbjct: 278 GAWVC 282
Score = 47.4 bits (111), Expect = 1e-04
Identities = 31/88 (35%), Positives = 40/88 (45%), Gaps = 3/88 (3%)
Query: 951 CSEQWIPFQNKCFLKIKPVSLTFSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATL 1010
C E+WI FQ KC+ K + A C G L S+ S EQDF+T +
Sbjct: 163 CPEKWINFQRKCYYFGKGTK-QWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGS-- 219
Query: 1011 WIGLRWTAYEKINKWTDNRELTYSNFHP 1038
WIGLR + W D + YSN+ P
Sbjct: 220 WIGLRNLDLKGEFIWVDGSHVDYSNWAP 247
Score = 41.6 bits (96), Expect = 0.007
Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 10/99 (10%)
Query: 1248 WIPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQLLYFNY 1307
WI FQ CY F T+ VH + + + ++SI +E +F+ + + ++
Sbjct: 167 WINFQRKCYYF-------GKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTK---HASH 216
Query: 1308 MASWVMLGITYRNKSLMWFDKTPLSYTHWRAGRPTIKNE 1346
SW+ L +W D + + Y++W G PT +++
Sbjct: 217 TGSWIGLRNLDLKGEFIWVDGSHVDYSNWAPGEPTSRSQ 255
Score = 35.0 bits (79), Expect = 0.63
Identities = 30/105 (28%), Positives = 44/105 (41%), Gaps = 15/105 (14%)
Query: 557 WTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFLEPASPG---GCVAMSTGKSVGKWEVKD 613
W GLR++D GE+ W V G V +SNW EP S CV M + G+W
Sbjct: 220 WIGLRNLDLKGEFIW--VDGSH--VDYSNWAPGEPTSRSQGEDCVMM---RGSGRWNDAF 272
Query: 614 CRSFKALSICKKMS-----GPLGPEEASPKPDDPCPEGWQSFPAS 653
C +C +++ G E+ P P+G P++
Sbjct: 273 CDRKLGAWVCDRLATCTPPASEGSAESMGPDSRPDPDGRLPTPSA 317
>gi|55742774 dectin-2 [Homo sapiens]
Length = 209
Score = 59.7 bits (143), Expect = 2e-08
Identities = 41/153 (26%), Positives = 72/153 (47%), Gaps = 26/153 (16%)
Query: 643 CPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFLT 702
CP W+SF +S CY + E++ W ++E+ C +GAHL F+ E + L
Sbjct: 79 CPASWKSFGSS--CYFISSEEKV-----WSKSEQNCVEMGAHLVVFNTEAEQNFIVQQLN 131
Query: 703 DQFSGQHWLWIGLNKRSPDLQGSWQWSDRTPV-STIIMPNEFQQDYDIRDCAAVKVFHRP 761
+ FS ++GL+ P +WQW D+TP + + + ++ CA++ VF +P
Sbjct: 132 ESFS----YFLGLS--DPQGNNNWQWIDKTPYEKNVRFWHLGEPNHSAEQCASI-VFWKP 184
Query: 762 WRRGWHFYDDREFIYLRPFACDTKLEWVCQIPK 794
GW+ C+T+ +C++ K
Sbjct: 185 TGWGWN-----------DVICETRRNSICEMNK 206
Score = 49.3 bits (116), Expect = 3e-05
Identities = 31/128 (24%), Positives = 53/128 (41%), Gaps = 5/128 (3%)
Query: 361 CDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEE 420
C A W CY + +E W K+ C + L+ ++ A+ +V +L NE
Sbjct: 79 CPASWKSFGSSCYFISSEEKVWSKSEQNCVEMGAHLVVFNTEAEQNFIVQQL-NESF--S 135
Query: 421 VWIGLKNINIPTLFQWSDGT--EVTLTYWDENEPNVPYNKTPNCVSYLGELGQWKVQSCE 478
++GL + +QW D T E + +W EPN + + V + W CE
Sbjct: 136 YFLGLSDPQGNNNWQWIDKTPYEKNVRFWHLGEPNHSAEQCASIVFWKPTGWGWNDVICE 195
Query: 479 EKLKYVCK 486
+ +C+
Sbjct: 196 TRRNSICE 203
Score = 45.4 bits (106), Expect = 5e-04
Identities = 28/127 (22%), Positives = 50/127 (39%), Gaps = 5/127 (3%)
Query: 216 CEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKEKEGIAKI 275
C +W+ FGS F + W ++ +C GA L+ N+ AE ++ ++ +
Sbjct: 79 CPASWKS---FGSSCYFISSEEKVWSKSEQNCVEMGAHLVVFNTEAEQNFIVQQLNESFS 135
Query: 276 FWIGLNQLYSARGWEWSDHKPL--NFLNWDPDRPSAPTIGGSSCARMDAESGLWQSFSCE 333
+++GL+ W+W D P N W P+ +S W CE
Sbjct: 136 YFLGLSDPQGNNNWQWIDKTPYEKNVRFWHLGEPNHSAEQCASIVFWKPTGWGWNDVICE 195
Query: 334 AQLPYVC 340
+ +C
Sbjct: 196 TRRNSIC 202
Score = 35.0 bits (79), Expect = 0.63
Identities = 27/103 (26%), Positives = 48/103 (46%), Gaps = 13/103 (12%)
Query: 1248 WIPFQNCCYNFIITKNRHMATTQDEVHTKCQKLNPKSHILSIRDEKENNFVLEQL-LYFN 1306
W F + CY FI ++ + + ++ C ++ +H++ E E NF+++QL F+
Sbjct: 83 WKSFGSSCY-FISSEEKVWSKSEQN----CVEMG--AHLVVFNTEAEQNFIVQQLNESFS 135
Query: 1307 YMASWVMLGITYRNKSLMWFDKTPL--SYTHWRAGRPTIKNEK 1347
Y ++ L N + W DKTP + W G P E+
Sbjct: 136 Y---FLGLSDPQGNNNWQWIDKTPYEKNVRFWHLGEPNHSAEQ 175
Score = 33.5 bits (75), Expect = 1.8
Identities = 29/129 (22%), Positives = 52/129 (40%), Gaps = 18/129 (13%)
Query: 1529 CPAAKENGSRWIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLM 1588
CPA+ W + CY +S++++ C + A +V E E F+ + +
Sbjct: 79 CPAS------WKSFGSSCYFISSEEKVWSKSEQNCV--EMGAHLVVFNTEAEQNFIVQQL 130
Query: 1589 RENNNITMRVWLGLSQHSVDQSWSWLDGS--EVTFVKWE-NKSKSGVGRCSMLIASNET- 1644
E+ +LGLS + +W W+D + E W + +C+ ++ T
Sbjct: 131 NES----FSYFLGLSDPQGNNNWQWIDKTPYEKNVRFWHLGEPNHSAEQCASIVFWKPTG 186
Query: 1645 --WKKVECE 1651
W V CE
Sbjct: 187 WGWNDVICE 195
>gi|7657333 C-type lectin domain family 4, member E [Homo sapiens]
Length = 219
Score = 58.9 bits (141), Expect = 4e-08
Identities = 46/143 (32%), Positives = 64/143 (44%), Gaps = 15/143 (10%)
Query: 213 ENGCEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKEKEGI 272
+N C NWE + SCY F+T T +SW + +C GA L+ INS E +L K+
Sbjct: 77 KNCCPLNWEYFQS--SCYFFSTDT-ISWALSLKNCSAMGAHLVVINSQEEQEFLSYKKPK 133
Query: 273 AKIFWIGLNQLYSARGWEWSDHKPL--NFLNWDPDRP-SAPTIGGSSCARMDAESG---L 326
+ F+IGL+ W+W D PL + WD P + T+ CA M S
Sbjct: 134 MREFFIGLSDQVVEGQWQWVDGTPLTKSLSFWDVGEPNNIATL--EDCATMRDSSNPRQN 191
Query: 327 WQSFSCEAQLPYVCR----KPLN 345
W +C +C PLN
Sbjct: 192 WNDVTCFLNYFRICEMVGINPLN 214
Score = 50.1 bits (118), Expect = 2e-05
Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 5/95 (5%)
Query: 361 CDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEE 420
C W CY ++ SW + C A + L+ I+S + E + K + E
Sbjct: 80 CPLNWEYFQSSCYFFSTDTISWALSLKNCSAMGAHLVVINSQEEQEFLSYK---KPKMRE 136
Query: 421 VWIGLKNINIPTLFQWSDGTEVT--LTYWDENEPN 453
+IGL + + +QW DGT +T L++WD EPN
Sbjct: 137 FFIGLSDQVVEGQWQWVDGTPLTKSLSFWDVGEPN 171
Score = 47.0 bits (110), Expect = 2e-04
Identities = 38/131 (29%), Positives = 63/131 (48%), Gaps = 23/131 (17%)
Query: 643 CPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFLT 702
CP W+ F +S CY F + I +W + + C A+GAHL + +E +EFL +
Sbjct: 80 CPLNWEYFQSS--CY-FFSTDTI----SWALSLKNCSAMGAHLVVINSQEE-QEFLSYKK 131
Query: 703 DQFSGQHWLWIGLNKRSPDLQGSWQWSDRTPVSTIIM------PNEFQQDYDIRDCAAVK 756
+ +IGL+ + ++G WQW D TP++ + PN + DCA ++
Sbjct: 132 PKMRE---FFIGLSDQV--VEGQWQWVDGTPLTKSLSFWDVGEPNNIA---TLEDCATMR 183
Query: 757 VFHRPWRRGWH 767
P R+ W+
Sbjct: 184 DSSNP-RQNWN 193
Score = 39.7 bits (91), Expect = 0.026
Identities = 35/138 (25%), Positives = 60/138 (43%), Gaps = 20/138 (14%)
Query: 1539 WIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRL---MRENNNIT 1595
W ++ CY S++ + K CS A +V I ++E +F+S MRE
Sbjct: 84 WEYFQSSCYFFSTDTISWALSLKNCSAM--GAHLVVINSQEEQEFLSYKKPKMRE----- 136
Query: 1596 MRVWLGLSQHSVDQSWSWLDGSEVT--FVKWENKSKSGVGR----CSMLIASN--ETWKK 1647
++GLS V+ W W+DG+ +T W+ + + +M +SN + W
Sbjct: 137 --FFIGLSDQVVEGQWQWVDGTPLTKSLSFWDVGEPNNIATLEDCATMRDSSNPRQNWND 194
Query: 1648 VECEHGFGRVVCKVPLGP 1665
V C + R+ V + P
Sbjct: 195 VTCFLNYFRICEMVGINP 212
Score = 37.7 bits (86), Expect = 0.097
Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 3/113 (2%)
Query: 922 CSTKLPFICEKYNVSSLEKYSPDSAAKVQCSEQWIPFQNKCFLKIKPVSLTFSQASDTCH 981
C K + E + S Y S K C W FQ+ C+ +++++ + C
Sbjct: 52 CDEKKFQLPENFTELSCYNYGSGSV-KNCCPLNWEYFQSSCYF-FSTDTISWALSLKNCS 109
Query: 982 SYGGTLPSVLSQIEQDFITSLLPDMEATLWIGLRWTAYEKINKWTDNRELTYS 1034
+ G L + SQ EQ+F++ P M +IGL E +W D LT S
Sbjct: 110 AMGAHLVVINSQEEQEFLSYKKPKMR-EFFIGLSDQVVEGQWQWVDGTPLTKS 161
Score = 34.7 bits (78), Expect = 0.82
Identities = 39/151 (25%), Positives = 57/151 (37%), Gaps = 18/151 (11%)
Query: 1077 FTSCSERHFVSLCQKYSEVKSRQTLQNASETVKYLN------NLYKIIPKTLTWHSAKRE 1130
F +C E+ F L + ++E+ + + LN + Y T++W + +
Sbjct: 49 FQTCDEKKF-QLPENFTELSCYNYGSGSVKNCCPLNWEYFQSSCYFFSTDTISWALSLKN 107
Query: 1131 CLKSNMQLVSITDPYQQAFLSVQALLHNSSLWIGLFSQDDELNFGWSDG----KRLHFSR 1186
C LV I +Q FLS + +IGL Q E + W DG K L F
Sbjct: 108 CSAMGAHLVVINSQEEQEFLSYKK-PKMREFFIGLSDQVVEGQWQWVDGTPLTKSLSFWD 166
Query: 1187 WAETN--GQLEDCVVLDTDG----FWKTVDC 1211
E N LEDC + W V C
Sbjct: 167 VGEPNNIATLEDCATMRDSSNPRQNWNDVTC 197
Score = 33.1 bits (74), Expect = 2.4
Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 1401 YEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHD 1460
++ Y ++W +L CS G HL +++Q Q FL K ++GLS
Sbjct: 87 FQSSCYFFSTDTISWALSLKNCSAMGAHLVVINSQEEQEFL-SYKKPKMREFFIGLSD-Q 144
Query: 1461 GSESSFEWSDGS 1472
E ++W DG+
Sbjct: 145 VVEGQWQWVDGT 156
>gi|223029517 CD209 molecule isoform 8 [Homo sapiens]
Length = 243
Score = 58.5 bits (140), Expect = 5e-08
Identities = 36/127 (28%), Positives = 59/127 (46%), Gaps = 9/127 (7%)
Query: 220 WEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKEKEGIAKIF-WI 278
WE G+CY F + + +W ++ +C+ GA L+ I SA E +L+ + + F W+
Sbjct: 97 WEWTFFQGNCY-FMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWM 155
Query: 279 GLNQLYSARGWEWSDHKPL--NFLN-WDPDRPSAPTIGGSSCARMDAESGLWQSFSCEAQ 335
GL+ L W+W D PL +F W+ P+ +G CA W C
Sbjct: 156 GLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPN--NVGEEDCAEFSGNG--WNDDKCNLA 211
Query: 336 LPYVCRK 342
++C+K
Sbjct: 212 KFWICKK 218
Score = 54.7 bits (130), Expect = 8e-07
Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 9/130 (6%)
Query: 361 CDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEE 420
C W G CY + N +W + CK + L+ I S + + +L +
Sbjct: 95 CPWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFL--QLQSSRSNRF 152
Query: 421 VWIGLKNINIPTLFQWSDGTEVTLT---YWDENEPNVPYNKTPNCVSYLGELGQWKVQSC 477
W+GL ++N +QW DG+ + + YW+ EPN + +C + G W C
Sbjct: 153 TWMGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEE--DCAEFSG--NGWNDDKC 208
Query: 478 EEKLKYVCKR 487
++CK+
Sbjct: 209 NLAKFWICKK 218
Score = 48.9 bits (115), Expect = 4e-05
Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 8/115 (6%)
Query: 1539 WIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRV 1598
W ++G+CY + ++ ++ C + A +V IK +E F+ +N T
Sbjct: 99 WTFFQGNCYFMSNSQRNWHDSITACK--EVGAQLVVIKSAEEQNFLQLQSSRSNRFT--- 153
Query: 1599 WLGLSQHSVDQSWSWLDGSEV--TFVK-WENKSKSGVGRCSMLIASNETWKKVEC 1650
W+GLS + + +W W+DGS + +F + W + VG S W +C
Sbjct: 154 WMGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEEDCAEFSGNGWNDDKC 208
Score = 48.5 bits (114), Expect = 6e-05
Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 7/109 (6%)
Query: 1110 YLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITDPYQQAFLSVQALLHNSSLWIGLFSQD 1169
+ N Y + WH + C + QLV I +Q FL +Q+ N W+GL +
Sbjct: 102 FQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLN 161
Query: 1170 DELNFGWSDGKRL------HFSRWAETNGQLEDCVVLDTDGFWKTVDCN 1212
E + W DG L +++R N EDC +G W CN
Sbjct: 162 QEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEEDCAEFSGNG-WNDDKCN 209
Score = 45.4 bits (106), Expect = 5e-04
Identities = 34/138 (24%), Positives = 56/138 (40%), Gaps = 10/138 (7%)
Query: 1401 YEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHD 1460
++ Y + + W++++ C + G L + + Q FL+ R W+GLS +
Sbjct: 102 FQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLN 161
Query: 1461 GSESSFEWSDGSTF--DYIPWKGQTSPGN-----CVLLDPKGTWKHEKCNSVKDGAICYK 1513
E +++W DGS + + + P N C G W +KCN K IC K
Sbjct: 162 -QEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEEDCAEFSGNG-WNDDKCNLAKFW-ICKK 218
Query: 1514 PTKSKKLSRLTYSSRCPA 1531
S + S PA
Sbjct: 219 SAASCSRDEEQFLSPAPA 236
Score = 44.7 bits (104), Expect = 8e-04
Identities = 26/93 (27%), Positives = 47/93 (50%), Gaps = 12/93 (12%)
Query: 642 PCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFL 701
PCP W F + CY + +++R NW ++ C+ +GA L +E + FL
Sbjct: 94 PCPWEWTFFQGN--CYFMSNSQR-----NWHDSITACKEVGAQLVVIKSAEE-QNFLQLQ 145
Query: 702 TDQFSGQHWLWIGLNKRSPDLQGSWQWSDRTPV 734
+ + + W+GL+ + + G+WQW D +P+
Sbjct: 146 SSR--SNRFTWMGLSDLNQE--GTWQWVDGSPL 174
Score = 32.0 bits (71), Expect = 5.3
Identities = 39/153 (25%), Positives = 55/153 (35%), Gaps = 19/153 (12%)
Query: 951 CSEQWIPFQNKCFLKIKPVSLTFSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATL 1010
C +W FQ C+ + + + C G L + S EQ+F+
Sbjct: 95 CPWEWTFFQGNCYF-MSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFT 153
Query: 1011 WIGLRWTAYEKINKWTDNRELTYSNFHPLLVSGRLRIPENFFEEESRYHCALILNLQKSP 1070
W+GL E +W D L S F G P N EE+ CA
Sbjct: 154 WMGLSDLNQEGTWQWVDGSPLLPS-FKQYWNRGE---PNNVGEED----CA--------E 197
Query: 1071 FTGT-WNFTSCSERHFVSLCQKYSEVKSRQTLQ 1102
F+G WN C+ F +C+K + SR Q
Sbjct: 198 FSGNGWNDDKCNLAKF-WICKKSAASCSRDEEQ 229
Score = 31.2 bits (69), Expect = 9.1
Identities = 34/121 (28%), Positives = 46/121 (38%), Gaps = 17/121 (14%)
Query: 530 LTITSRFEQEYLNDLMKKYDKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSN-WNF 588
+ I S EQ +L + ++ W GL D++ G + W V G +F WN
Sbjct: 131 VVIKSAEEQNFL----QLQSSRSNRFTWMGLSDLNQEGTWQW--VDGSPLLPSFKQYWNR 184
Query: 589 LEPASPG--GCVAMSTGKSVGKWEVKDCRSFKALSICKKMSGPLGPEE---ASPKPDDPC 643
EP + G C S W C K ICKK + +E SP P P
Sbjct: 185 GEPNNVGEEDCAEFSG----NGWNDDKCNLAK-FWICKKSAASCSRDEEQFLSPAPATPN 239
Query: 644 P 644
P
Sbjct: 240 P 240
>gi|223278347 C-type lectin domain family 4, member M isoform 9
[Homo sapiens]
Length = 353
Score = 58.5 bits (140), Expect = 5e-08
Identities = 37/152 (24%), Positives = 65/152 (42%), Gaps = 12/152 (7%)
Query: 349 ELTDVWTYSDT---RCDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADV 405
ELTD+ T + C W G CY + N +W + C+ + L+ I + +
Sbjct: 207 ELTDLKTAFERLCRHCPKDWTFFQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQ 266
Query: 406 EVVVTKLHNEDIKEEVWIGLKNINIPTLFQWSDGTEVTLT---YWDENEPNVPYNKTPNC 462
+ +L W+GL ++N +QW DG+ ++ + YW+ EPN N+ +C
Sbjct: 267 NFL--QLQTSRSNRFSWMGLSDLNQEGTWQWVDGSPLSPSFQRYWNSGEPNNSGNE--DC 322
Query: 463 VSYLGELGQWKVQSCEEKLKYVCKRKGEKLND 494
+ G W C+ ++CK+ D
Sbjct: 323 AEFSG--SGWNDNRCDVDNYWICKKPAACFRD 352
Score = 57.4 bits (137), Expect = 1e-07
Identities = 35/132 (26%), Positives = 60/132 (45%), Gaps = 11/132 (8%)
Query: 216 CEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKEKEGIAKI 275
C +W + G+CY F + + +W ++ +CQ A L+ I +A E +L+ + +
Sbjct: 222 CPKDWTFFQ--GNCY-FMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNR 278
Query: 276 F-WIGLNQLYSARGWEWSDHKPLN---FLNWDPDRPSAPTIGGSSCARMDAESGLWQSFS 331
F W+GL+ L W+W D PL+ W+ P+ G CA W
Sbjct: 279 FSWMGLSDLNQEGTWQWVDGSPLSPSFQRYWNSGEPN--NSGNEDCAEFSGSG--WNDNR 334
Query: 332 CEAQLPYVCRKP 343
C+ ++C+KP
Sbjct: 335 CDVDNYWICKKP 346
Score = 47.4 bits (111), Expect = 1e-04
Identities = 41/158 (25%), Positives = 66/158 (41%), Gaps = 40/158 (25%)
Query: 643 CPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFLT 702
CP+ W F + CY + +++R NW ++ CQ + A L +E + FL T
Sbjct: 222 CPKDWTFFQGN--CYFMSNSQR-----NWHDSVTACQEVRAQLVVIKTAEE-QNFLQLQT 273
Query: 703 DQFSGQHWLWIGLNKRSPDLQGSWQWSDRTPVSTIIM-------PNEFQQDYDIRDCAAV 755
+ + W+GL+ + + G+WQW D +P+S PN + DCA
Sbjct: 274 SR--SNRFSWMGLSDLNQE--GTWQWVDGSPLSPSFQRYWNSGEPNNSGNE----DCAEF 325
Query: 756 KVFHRPWRRGWHFYDDREFIYLRPFACDTKLEWVCQIP 793
GW+ D+R CD W+C+ P
Sbjct: 326 S------GSGWN--DNR---------CDVDNYWICKKP 346
Score = 46.2 bits (108), Expect = 3e-04
Identities = 30/127 (23%), Positives = 56/127 (44%), Gaps = 9/127 (7%)
Query: 1539 WIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRV 1598
W ++G+CY + ++ ++ C + A +V IK +E F+ +N +
Sbjct: 226 WTFFQGNCYFMSNSQRNWHDSVTACQ--EVRAQLVVIKTAEEQNFLQLQTSRSNRFS--- 280
Query: 1599 WLGLSQHSVDQSWSWLDGSEV--TFVK-WENKSKSGVGRCSMLIASNETWKKVECEHGFG 1655
W+GLS + + +W W+DGS + +F + W + + G S W C+
Sbjct: 281 WMGLSDLNQEGTWQWVDGSPLSPSFQRYWNSGEPNNSGNEDCAEFSGSGWNDNRCDVD-N 339
Query: 1656 RVVCKVP 1662
+CK P
Sbjct: 340 YWICKKP 346
Score = 43.9 bits (102), Expect = 0.001
Identities = 29/109 (26%), Positives = 42/109 (38%), Gaps = 7/109 (6%)
Query: 1110 YLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITDPYQQAFLSVQALLHNSSLWIGLFSQD 1169
+ N Y + WH + C + QLV I +Q FL +Q N W+GL +
Sbjct: 229 FQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNRFSWMGLSDLN 288
Query: 1170 DELNFGWSDGKRL------HFSRWAETNGQLEDCVVLDTDGFWKTVDCN 1212
E + W DG L +++ N EDC G W C+
Sbjct: 289 QEGTWQWVDGSPLSPSFQRYWNSGEPNNSGNEDCAEFSGSG-WNDNRCD 336
Score = 37.4 bits (85), Expect = 0.13
Identities = 28/121 (23%), Positives = 49/121 (40%), Gaps = 10/121 (8%)
Query: 1401 YEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHD 1460
++ Y + + W++++ C + L + Q FL+ R W+GLS +
Sbjct: 229 FQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNRFSWMGLSDLN 288
Query: 1461 GSESSFEWSDGSTF--DYIPWKGQTSPGN-----CVLLDPKGTWKHEKCNSVKDGAICYK 1513
E +++W DGS + + P N C G W +C+ V + IC K
Sbjct: 289 -QEGTWQWVDGSPLSPSFQRYWNSGEPNNSGNEDCAEFSGSG-WNDNRCD-VDNYWICKK 345
Query: 1514 P 1514
P
Sbjct: 346 P 346
>gi|223278337 C-type lectin domain family 4, member M isoform 12
[Homo sapiens]
Length = 375
Score = 58.5 bits (140), Expect = 5e-08
Identities = 37/152 (24%), Positives = 65/152 (42%), Gaps = 12/152 (7%)
Query: 349 ELTDVWTYSDT---RCDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADV 405
ELTD+ T + C W G CY + N +W + C+ + L+ I + +
Sbjct: 229 ELTDLKTAFERLCRHCPKDWTFFQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQ 288
Query: 406 EVVVTKLHNEDIKEEVWIGLKNINIPTLFQWSDGTEVTLT---YWDENEPNVPYNKTPNC 462
+ +L W+GL ++N +QW DG+ ++ + YW+ EPN N+ +C
Sbjct: 289 NFL--QLQTSRSNRFSWMGLSDLNQEGTWQWVDGSPLSPSFQRYWNSGEPNNSGNE--DC 344
Query: 463 VSYLGELGQWKVQSCEEKLKYVCKRKGEKLND 494
+ G W C+ ++CK+ D
Sbjct: 345 AEFSG--SGWNDNRCDVDNYWICKKPAACFRD 374
Score = 57.4 bits (137), Expect = 1e-07
Identities = 35/132 (26%), Positives = 60/132 (45%), Gaps = 11/132 (8%)
Query: 216 CEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKEKEGIAKI 275
C +W + G+CY F + + +W ++ +CQ A L+ I +A E +L+ + +
Sbjct: 244 CPKDWTFFQ--GNCY-FMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNR 300
Query: 276 F-WIGLNQLYSARGWEWSDHKPLN---FLNWDPDRPSAPTIGGSSCARMDAESGLWQSFS 331
F W+GL+ L W+W D PL+ W+ P+ G CA W
Sbjct: 301 FSWMGLSDLNQEGTWQWVDGSPLSPSFQRYWNSGEPN--NSGNEDCAEFSGSG--WNDNR 356
Query: 332 CEAQLPYVCRKP 343
C+ ++C+KP
Sbjct: 357 CDVDNYWICKKP 368
Score = 47.4 bits (111), Expect = 1e-04
Identities = 41/158 (25%), Positives = 66/158 (41%), Gaps = 40/158 (25%)
Query: 643 CPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFLT 702
CP+ W F + CY + +++R NW ++ CQ + A L +E + FL T
Sbjct: 244 CPKDWTFFQGN--CYFMSNSQR-----NWHDSVTACQEVRAQLVVIKTAEE-QNFLQLQT 295
Query: 703 DQFSGQHWLWIGLNKRSPDLQGSWQWSDRTPVSTIIM-------PNEFQQDYDIRDCAAV 755
+ + W+GL+ + + G+WQW D +P+S PN + DCA
Sbjct: 296 SR--SNRFSWMGLSDLNQE--GTWQWVDGSPLSPSFQRYWNSGEPNNSGNE----DCAEF 347
Query: 756 KVFHRPWRRGWHFYDDREFIYLRPFACDTKLEWVCQIP 793
GW+ D+R CD W+C+ P
Sbjct: 348 S------GSGWN--DNR---------CDVDNYWICKKP 368
Score = 46.2 bits (108), Expect = 3e-04
Identities = 30/127 (23%), Positives = 56/127 (44%), Gaps = 9/127 (7%)
Query: 1539 WIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRV 1598
W ++G+CY + ++ ++ C + A +V IK +E F+ +N +
Sbjct: 248 WTFFQGNCYFMSNSQRNWHDSVTACQ--EVRAQLVVIKTAEEQNFLQLQTSRSNRFS--- 302
Query: 1599 WLGLSQHSVDQSWSWLDGSEV--TFVK-WENKSKSGVGRCSMLIASNETWKKVECEHGFG 1655
W+GLS + + +W W+DGS + +F + W + + G S W C+
Sbjct: 303 WMGLSDLNQEGTWQWVDGSPLSPSFQRYWNSGEPNNSGNEDCAEFSGSGWNDNRCDVD-N 361
Query: 1656 RVVCKVP 1662
+CK P
Sbjct: 362 YWICKKP 368
Score = 43.9 bits (102), Expect = 0.001
Identities = 29/109 (26%), Positives = 42/109 (38%), Gaps = 7/109 (6%)
Query: 1110 YLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITDPYQQAFLSVQALLHNSSLWIGLFSQD 1169
+ N Y + WH + C + QLV I +Q FL +Q N W+GL +
Sbjct: 251 FQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNRFSWMGLSDLN 310
Query: 1170 DELNFGWSDGKRL------HFSRWAETNGQLEDCVVLDTDGFWKTVDCN 1212
E + W DG L +++ N EDC G W C+
Sbjct: 311 QEGTWQWVDGSPLSPSFQRYWNSGEPNNSGNEDCAEFSGSG-WNDNRCD 358
Score = 37.4 bits (85), Expect = 0.13
Identities = 28/121 (23%), Positives = 49/121 (40%), Gaps = 10/121 (8%)
Query: 1401 YEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHD 1460
++ Y + + W++++ C + L + Q FL+ R W+GLS +
Sbjct: 251 FQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNRFSWMGLSDLN 310
Query: 1461 GSESSFEWSDGSTF--DYIPWKGQTSPGN-----CVLLDPKGTWKHEKCNSVKDGAICYK 1513
E +++W DGS + + P N C G W +C+ V + IC K
Sbjct: 311 -QEGTWQWVDGSPLSPSFQRYWNSGEPNNSGNEDCAEFSGSG-WNDNRCD-VDNYWICKK 367
Query: 1514 P 1514
P
Sbjct: 368 P 368
>gi|223278335 C-type lectin domain family 4, member M isoform 2
[Homo sapiens]
Length = 348
Score = 58.5 bits (140), Expect = 5e-08
Identities = 37/152 (24%), Positives = 65/152 (42%), Gaps = 12/152 (7%)
Query: 349 ELTDVWTYSDT---RCDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADV 405
ELTD+ T + C W G CY + N +W + C+ + L+ I + +
Sbjct: 202 ELTDLKTAFERLCRHCPKDWTFFQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQ 261
Query: 406 EVVVTKLHNEDIKEEVWIGLKNINIPTLFQWSDGTEVTLT---YWDENEPNVPYNKTPNC 462
+ +L W+GL ++N +QW DG+ ++ + YW+ EPN N+ +C
Sbjct: 262 NFL--QLQTSRSNRFSWMGLSDLNQEGTWQWVDGSPLSPSFQRYWNSGEPNNSGNE--DC 317
Query: 463 VSYLGELGQWKVQSCEEKLKYVCKRKGEKLND 494
+ G W C+ ++CK+ D
Sbjct: 318 AEFSG--SGWNDNRCDVDNYWICKKPAACFRD 347
Score = 57.4 bits (137), Expect = 1e-07
Identities = 35/132 (26%), Positives = 60/132 (45%), Gaps = 11/132 (8%)
Query: 216 CEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKEKEGIAKI 275
C +W + G+CY F + + +W ++ +CQ A L+ I +A E +L+ + +
Sbjct: 217 CPKDWTFFQ--GNCY-FMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNR 273
Query: 276 F-WIGLNQLYSARGWEWSDHKPLN---FLNWDPDRPSAPTIGGSSCARMDAESGLWQSFS 331
F W+GL+ L W+W D PL+ W+ P+ G CA W
Sbjct: 274 FSWMGLSDLNQEGTWQWVDGSPLSPSFQRYWNSGEPN--NSGNEDCAEFSGSG--WNDNR 329
Query: 332 CEAQLPYVCRKP 343
C+ ++C+KP
Sbjct: 330 CDVDNYWICKKP 341
Score = 47.4 bits (111), Expect = 1e-04
Identities = 41/158 (25%), Positives = 66/158 (41%), Gaps = 40/158 (25%)
Query: 643 CPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFLT 702
CP+ W F + CY + +++R NW ++ CQ + A L +E + FL T
Sbjct: 217 CPKDWTFFQGN--CYFMSNSQR-----NWHDSVTACQEVRAQLVVIKTAEE-QNFLQLQT 268
Query: 703 DQFSGQHWLWIGLNKRSPDLQGSWQWSDRTPVSTIIM-------PNEFQQDYDIRDCAAV 755
+ + W+GL+ + + G+WQW D +P+S PN + DCA
Sbjct: 269 SR--SNRFSWMGLSDLNQE--GTWQWVDGSPLSPSFQRYWNSGEPNNSGNE----DCAEF 320
Query: 756 KVFHRPWRRGWHFYDDREFIYLRPFACDTKLEWVCQIP 793
GW+ D+R CD W+C+ P
Sbjct: 321 S------GSGWN--DNR---------CDVDNYWICKKP 341
Score = 46.2 bits (108), Expect = 3e-04
Identities = 30/127 (23%), Positives = 56/127 (44%), Gaps = 9/127 (7%)
Query: 1539 WIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRV 1598
W ++G+CY + ++ ++ C + A +V IK +E F+ +N +
Sbjct: 221 WTFFQGNCYFMSNSQRNWHDSVTACQ--EVRAQLVVIKTAEEQNFLQLQTSRSNRFS--- 275
Query: 1599 WLGLSQHSVDQSWSWLDGSEV--TFVK-WENKSKSGVGRCSMLIASNETWKKVECEHGFG 1655
W+GLS + + +W W+DGS + +F + W + + G S W C+
Sbjct: 276 WMGLSDLNQEGTWQWVDGSPLSPSFQRYWNSGEPNNSGNEDCAEFSGSGWNDNRCDVD-N 334
Query: 1656 RVVCKVP 1662
+CK P
Sbjct: 335 YWICKKP 341
Score = 43.9 bits (102), Expect = 0.001
Identities = 29/109 (26%), Positives = 42/109 (38%), Gaps = 7/109 (6%)
Query: 1110 YLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITDPYQQAFLSVQALLHNSSLWIGLFSQD 1169
+ N Y + WH + C + QLV I +Q FL +Q N W+GL +
Sbjct: 224 FQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNRFSWMGLSDLN 283
Query: 1170 DELNFGWSDGKRL------HFSRWAETNGQLEDCVVLDTDGFWKTVDCN 1212
E + W DG L +++ N EDC G W C+
Sbjct: 284 QEGTWQWVDGSPLSPSFQRYWNSGEPNNSGNEDCAEFSGSG-WNDNRCD 331
Score = 37.4 bits (85), Expect = 0.13
Identities = 28/121 (23%), Positives = 49/121 (40%), Gaps = 10/121 (8%)
Query: 1401 YEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHD 1460
++ Y + + W++++ C + L + Q FL+ R W+GLS +
Sbjct: 224 FQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNRFSWMGLSDLN 283
Query: 1461 GSESSFEWSDGSTF--DYIPWKGQTSPGN-----CVLLDPKGTWKHEKCNSVKDGAICYK 1513
E +++W DGS + + P N C G W +C+ V + IC K
Sbjct: 284 -QEGTWQWVDGSPLSPSFQRYWNSGEPNNSGNEDCAEFSGSG-WNDNRCD-VDNYWICKK 340
Query: 1514 P 1514
P
Sbjct: 341 P 341
>gi|223029386 CD209 molecule isoform 3 [Homo sapiens]
Length = 380
Score = 58.5 bits (140), Expect = 5e-08
Identities = 36/127 (28%), Positives = 59/127 (46%), Gaps = 9/127 (7%)
Query: 220 WEKNEQFGSCYQFNTQTALSWKEAYVSCQNQGADLLSINSAAELTYLKEKEGIAKIF-WI 278
WE G+CY F + + +W ++ +C+ GA L+ I SA E +L+ + + F W+
Sbjct: 234 WEWTFFQGNCY-FMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWM 292
Query: 279 GLNQLYSARGWEWSDHKPL--NFLN-WDPDRPSAPTIGGSSCARMDAESGLWQSFSCEAQ 335
GL+ L W+W D PL +F W+ P+ +G CA W C
Sbjct: 293 GLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPN--NVGEEDCAEFSGNG--WNDDKCNLA 348
Query: 336 LPYVCRK 342
++C+K
Sbjct: 349 KFWICKK 355
Score = 54.7 bits (130), Expect = 8e-07
Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 9/130 (6%)
Query: 361 CDAGWLPNNGFCYLLVNESNSWDKAHAKCKAFSSDLISIHSLADVEVVVTKLHNEDIKEE 420
C W G CY + N +W + CK + L+ I S + + +L +
Sbjct: 232 CPWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFL--QLQSSRSNRF 289
Query: 421 VWIGLKNINIPTLFQWSDGTEVTLT---YWDENEPNVPYNKTPNCVSYLGELGQWKVQSC 477
W+GL ++N +QW DG+ + + YW+ EPN + +C + G W C
Sbjct: 290 TWMGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEE--DCAEFSG--NGWNDDKC 345
Query: 478 EEKLKYVCKR 487
++CK+
Sbjct: 346 NLAKFWICKK 355
Score = 48.9 bits (115), Expect = 4e-05
Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 8/115 (6%)
Query: 1539 WIQYKGHCYKSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRLMRENNNITMRV 1598
W ++G+CY + ++ ++ C + A +V IK +E F+ +N T
Sbjct: 236 WTFFQGNCYFMSNSQRNWHDSITACK--EVGAQLVVIKSAEEQNFLQLQSSRSNRFT--- 290
Query: 1599 WLGLSQHSVDQSWSWLDGSEV--TFVK-WENKSKSGVGRCSMLIASNETWKKVEC 1650
W+GLS + + +W W+DGS + +F + W + VG S W +C
Sbjct: 291 WMGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEEDCAEFSGNGWNDDKC 345
Score = 48.5 bits (114), Expect = 6e-05
Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 7/109 (6%)
Query: 1110 YLNNLYKIIPKTLTWHSAKRECLKSNMQLVSITDPYQQAFLSVQALLHNSSLWIGLFSQD 1169
+ N Y + WH + C + QLV I +Q FL +Q+ N W+GL +
Sbjct: 239 FQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLN 298
Query: 1170 DELNFGWSDGKRL------HFSRWAETNGQLEDCVVLDTDGFWKTVDCN 1212
E + W DG L +++R N EDC +G W CN
Sbjct: 299 QEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEEDCAEFSGNG-WNDDKCN 346
Score = 45.4 bits (106), Expect = 5e-04
Identities = 34/138 (24%), Positives = 56/138 (40%), Gaps = 10/138 (7%)
Query: 1401 YEDGIYSVIQKKVTWYEALNMCSQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSSHD 1460
++ Y + + W++++ C + G L + + Q FL+ R W+GLS +
Sbjct: 239 FQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLN 298
Query: 1461 GSESSFEWSDGSTF--DYIPWKGQTSPGN-----CVLLDPKGTWKHEKCNSVKDGAICYK 1513
E +++W DGS + + + P N C G W +KCN K IC K
Sbjct: 299 -QEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEEDCAEFSGNG-WNDDKCNLAKFW-ICKK 355
Query: 1514 PTKSKKLSRLTYSSRCPA 1531
S + S PA
Sbjct: 356 SAASCSRDEEQFLSPAPA 373
Score = 44.7 bits (104), Expect = 8e-04
Identities = 26/93 (27%), Positives = 47/93 (50%), Gaps = 12/93 (12%)
Query: 642 PCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFCQALGAHLSSFSHVDEIKEFLHFL 701
PCP W F + CY + +++R NW ++ C+ +GA L +E + FL
Sbjct: 231 PCPWEWTFFQGN--CYFMSNSQR-----NWHDSITACKEVGAQLVVIKSAEE-QNFLQLQ 282
Query: 702 TDQFSGQHWLWIGLNKRSPDLQGSWQWSDRTPV 734
+ + + W+GL+ + + G+WQW D +P+
Sbjct: 283 SSR--SNRFTWMGLSDLNQE--GTWQWVDGSPL 311
Score = 32.0 bits (71), Expect = 5.3
Identities = 39/153 (25%), Positives = 55/153 (35%), Gaps = 19/153 (12%)
Query: 951 CSEQWIPFQNKCFLKIKPVSLTFSQASDTCHSYGGTLPSVLSQIEQDFITSLLPDMEATL 1010
C +W FQ C+ + + + C G L + S EQ+F+
Sbjct: 232 CPWEWTFFQGNCYF-MSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFT 290
Query: 1011 WIGLRWTAYEKINKWTDNRELTYSNFHPLLVSGRLRIPENFFEEESRYHCALILNLQKSP 1070
W+GL E +W D L S F G P N EE+ CA
Sbjct: 291 WMGLSDLNQEGTWQWVDGSPLLPS-FKQYWNRGE---PNNVGEED----CA--------E 334
Query: 1071 FTGT-WNFTSCSERHFVSLCQKYSEVKSRQTLQ 1102
F+G WN C+ F +C+K + SR Q
Sbjct: 335 FSGNGWNDDKCNLAKF-WICKKSAASCSRDEEQ 366
Score = 31.2 bits (69), Expect = 9.1
Identities = 34/121 (28%), Positives = 46/121 (38%), Gaps = 17/121 (14%)
Query: 530 LTITSRFEQEYLNDLMKKYDKSLRKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSN-WNF 588
+ I S EQ +L + ++ W GL D++ G + W V G +F WN
Sbjct: 268 VVIKSAEEQNFL----QLQSSRSNRFTWMGLSDLNQEGTWQW--VDGSPLLPSFKQYWNR 321
Query: 589 LEPASPG--GCVAMSTGKSVGKWEVKDCRSFKALSICKKMSGPLGPEE---ASPKPDDPC 643
EP + G C S W C K ICKK + +E SP P P
Sbjct: 322 GEPNNVGEEDCAEFSG----NGWNDDKCNLAK-FWICKKSAASCSRDEEQFLSPAPATPN 376
Query: 644 P 644
P
Sbjct: 377 P 377
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.448
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 74,895,585
Number of Sequences: 37866
Number of extensions: 3651113
Number of successful extensions: 9323
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 99
Number of HSP's successfully gapped in prelim test: 56
Number of HSP's that attempted gapping in prelim test: 7679
Number of HSP's gapped (non-prelim): 904
length of query: 1722
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1606
effective length of database: 13,855,062
effective search space: 22251229572
effective search space used: 22251229572
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.