Search of human proteins with 109637782

Search of human proteins with 109637782

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|109637782 GLIS family zinc finger 3 isoform b [Homo sapiens]
         (775 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|109637784 GLIS family zinc finger 3 isoform a [Homo sapiens]      1603   0.0  
gi|109637782 GLIS family zinc finger 3 isoform b [Homo sapiens]      1603   0.0  
gi|166706915 GLIS family zinc finger 1 [Homo sapiens]                 397   e-110
gi|86991432 GLI-Kruppel family member GLI2 [Homo sapiens]             275   9e-74
gi|4885279 GLI family zinc finger 1 isoform 1 [Homo sapiens]          263   6e-70
gi|119393899 GLI-Kruppel family member GLI3 [Homo sapiens]            261   2e-69
gi|229892345 GLI family zinc finger 1 isoform 2 [Homo sapiens]        229   6e-60
gi|110431364 GLIS family zinc finger 2 [Homo sapiens]                 206   9e-53
gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]   197   4e-50
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]    187   3e-47
gi|22547182 zinc finger protein of the cerebellum 1 [Homo sapiens]    183   5e-46
gi|22547201 zinc finger protein of the cerebellum 4 [Homo sapiens]    182   8e-46
gi|4507973 zinc finger protein of the cerebellum 3 [Homo sapiens]     176   7e-44
gi|116014328 zinc finger protein 143 [Homo sapiens]                   124   4e-28
gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]   117   3e-26
gi|133922582 zinc finger protein 358 [Homo sapiens]                   115   1e-25
gi|90193619 nuclear matrix transcription factor 4 isoform c [Hom...   114   3e-25
gi|90193617 nuclear matrix transcription factor 4 isoform b [Hom...   114   3e-25
gi|90193615 nuclear matrix transcription factor 4 isoform b [Hom...   114   3e-25
gi|90193613 nuclear matrix transcription factor 4 isoform a [Hom...   114   3e-25
gi|90193611 nuclear matrix transcription factor 4 isoform a [Hom...   114   3e-25
gi|36054194 nuclear matrix transcription factor 4 isoform a [Hom...   114   3e-25
gi|21361146 zinc finger protein 76 (expressed in testis) [Homo s...   113   6e-25
gi|38570115 zinc finger protein 362 [Homo sapiens]                    112   2e-24
gi|64368880 zinc finger and SCAN domain containing 25 [Homo sapi...   110   6e-24
gi|209180475 nuclear matrix transcription factor 4 isoform d [Ho...   109   8e-24
gi|122937229 zinc finger protein 629 [Homo sapiens]                   108   1e-23
gi|55769561 zinc finger protein 21 isoform 2 [Homo sapiens]           107   3e-23
gi|55769559 zinc finger protein 21 isoform 1 [Homo sapiens]           107   3e-23
gi|223468648 zinc finger protein 389 [Homo sapiens]                   105   2e-22

>gi|109637784 GLIS family zinc finger 3 isoform a [Homo sapiens]
          Length = 930

 Score = 1603 bits (4151), Expect = 0.0
 Identities = 775/775 (100%), Positives = 775/775 (100%)

Query: 1   MMVQRLGLISPPASQVSTACNQISPSLQRAMNAANLNIPPSDTRSLISRESLASTTLSLT 60
           MMVQRLGLISPPASQVSTACNQISPSLQRAMNAANLNIPPSDTRSLISRESLASTTLSLT
Sbjct: 156 MMVQRLGLISPPASQVSTACNQISPSLQRAMNAANLNIPPSDTRSLISRESLASTTLSLT 215

Query: 61  ESQSASSMKQEWSQGYRALPSLSNHGSQNGLDLGDLLSLPPGTSMSSNSVSNSLPSYLFG 120
           ESQSASSMKQEWSQGYRALPSLSNHGSQNGLDLGDLLSLPPGTSMSSNSVSNSLPSYLFG
Sbjct: 216 ESQSASSMKQEWSQGYRALPSLSNHGSQNGLDLGDLLSLPPGTSMSSNSVSNSLPSYLFG 275

Query: 121 TESSHSPYPSPRHSSTRSHSARSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAYINGSR 180
           TESSHSPYPSPRHSSTRSHSARSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAYINGSR
Sbjct: 276 TESSHSPYPSPRHSSTRSHSARSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAYINGSR 335

Query: 181 ASPANLSPQPEVYGHFLGVRGSCIPQPRPVPGSQKGVLVAPGGLALPAYGEDGALEHERM 240
           ASPANLSPQPEVYGHFLGVRGSCIPQPRPVPGSQKGVLVAPGGLALPAYGEDGALEHERM
Sbjct: 336 ASPANLSPQPEVYGHFLGVRGSCIPQPRPVPGSQKGVLVAPGGLALPAYGEDGALEHERM 395

Query: 241 QQLEHGGLQPGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPPAPPLPPLPPP 300
           QQLEHGGLQPGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPPAPPLPPLPPP
Sbjct: 396 QQLEHGGLQPGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPPAPPLPPLPPP 455

Query: 301 PGPPPPYHAHAHLHHPELGPHAQQLALPQATLDDDGEMDGIGGKHCCRWIDCSALYDQQE 360
           PGPPPPYHAHAHLHHPELGPHAQQLALPQATLDDDGEMDGIGGKHCCRWIDCSALYDQQE
Sbjct: 456 PGPPPPYHAHAHLHHPELGPHAQQLALPQATLDDDGEMDGIGGKHCCRWIDCSALYDQQE 515

Query: 361 ELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCE 420
           ELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCE
Sbjct: 516 ELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCE 575

Query: 421 KAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCT 480
           KAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCT
Sbjct: 576 KAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCT 635

Query: 481 KRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELHPDLLTDCLTVQSLQPATSPRDAAAEG 540
           KRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELHPDLLTDCLTVQSLQPATSPRDAAAEG
Sbjct: 636 KRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELHPDLLTDCLTVQSLQPATSPRDAAAEG 695

Query: 541 TVGRSPGPGPDLYSAPIFSSNYSSRSGTAAGAVPPPHPVSHPSPGHNVQGSPHNPSSQLP 600
           TVGRSPGPGPDLYSAPIFSSNYSSRSGTAAGAVPPPHPVSHPSPGHNVQGSPHNPSSQLP
Sbjct: 696 TVGRSPGPGPDLYSAPIFSSNYSSRSGTAAGAVPPPHPVSHPSPGHNVQGSPHNPSSQLP 755

Query: 601 PLTAVDAGAERFAPSAPSPHHISPRRVPAPSSILQRTQPPYTQQPSGSHLKSYQPETNSS 660
           PLTAVDAGAERFAPSAPSPHHISPRRVPAPSSILQRTQPPYTQQPSGSHLKSYQPETNSS
Sbjct: 756 PLTAVDAGAERFAPSAPSPHHISPRRVPAPSSILQRTQPPYTQQPSGSHLKSYQPETNSS 815

Query: 661 FQPNGIHVHGFYGQLQKFCPPHYPDSQRIVPPVSSCSVVPSFEDCLVPTSMGQASFDVFH 720
           FQPNGIHVHGFYGQLQKFCPPHYPDSQRIVPPVSSCSVVPSFEDCLVPTSMGQASFDVFH
Sbjct: 816 FQPNGIHVHGFYGQLQKFCPPHYPDSQRIVPPVSSCSVVPSFEDCLVPTSMGQASFDVFH 875

Query: 721 RAFSTHSGITVYDLPSSSSSLFGESLRSGAEDATFLQISTVDRCPSQLSSVYTEG 775
           RAFSTHSGITVYDLPSSSSSLFGESLRSGAEDATFLQISTVDRCPSQLSSVYTEG
Sbjct: 876 RAFSTHSGITVYDLPSSSSSLFGESLRSGAEDATFLQISTVDRCPSQLSSVYTEG 930


>gi|109637782 GLIS family zinc finger 3 isoform b [Homo sapiens]
          Length = 775

 Score = 1603 bits (4151), Expect = 0.0
 Identities = 775/775 (100%), Positives = 775/775 (100%)

Query: 1   MMVQRLGLISPPASQVSTACNQISPSLQRAMNAANLNIPPSDTRSLISRESLASTTLSLT 60
           MMVQRLGLISPPASQVSTACNQISPSLQRAMNAANLNIPPSDTRSLISRESLASTTLSLT
Sbjct: 1   MMVQRLGLISPPASQVSTACNQISPSLQRAMNAANLNIPPSDTRSLISRESLASTTLSLT 60

Query: 61  ESQSASSMKQEWSQGYRALPSLSNHGSQNGLDLGDLLSLPPGTSMSSNSVSNSLPSYLFG 120
           ESQSASSMKQEWSQGYRALPSLSNHGSQNGLDLGDLLSLPPGTSMSSNSVSNSLPSYLFG
Sbjct: 61  ESQSASSMKQEWSQGYRALPSLSNHGSQNGLDLGDLLSLPPGTSMSSNSVSNSLPSYLFG 120

Query: 121 TESSHSPYPSPRHSSTRSHSARSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAYINGSR 180
           TESSHSPYPSPRHSSTRSHSARSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAYINGSR
Sbjct: 121 TESSHSPYPSPRHSSTRSHSARSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAYINGSR 180

Query: 181 ASPANLSPQPEVYGHFLGVRGSCIPQPRPVPGSQKGVLVAPGGLALPAYGEDGALEHERM 240
           ASPANLSPQPEVYGHFLGVRGSCIPQPRPVPGSQKGVLVAPGGLALPAYGEDGALEHERM
Sbjct: 181 ASPANLSPQPEVYGHFLGVRGSCIPQPRPVPGSQKGVLVAPGGLALPAYGEDGALEHERM 240

Query: 241 QQLEHGGLQPGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPPAPPLPPLPPP 300
           QQLEHGGLQPGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPPAPPLPPLPPP
Sbjct: 241 QQLEHGGLQPGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPPAPPLPPLPPP 300

Query: 301 PGPPPPYHAHAHLHHPELGPHAQQLALPQATLDDDGEMDGIGGKHCCRWIDCSALYDQQE 360
           PGPPPPYHAHAHLHHPELGPHAQQLALPQATLDDDGEMDGIGGKHCCRWIDCSALYDQQE
Sbjct: 301 PGPPPPYHAHAHLHHPELGPHAQQLALPQATLDDDGEMDGIGGKHCCRWIDCSALYDQQE 360

Query: 361 ELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCE 420
           ELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCE
Sbjct: 361 ELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCE 420

Query: 421 KAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCT 480
           KAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCT
Sbjct: 421 KAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCT 480

Query: 481 KRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELHPDLLTDCLTVQSLQPATSPRDAAAEG 540
           KRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELHPDLLTDCLTVQSLQPATSPRDAAAEG
Sbjct: 481 KRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELHPDLLTDCLTVQSLQPATSPRDAAAEG 540

Query: 541 TVGRSPGPGPDLYSAPIFSSNYSSRSGTAAGAVPPPHPVSHPSPGHNVQGSPHNPSSQLP 600
           TVGRSPGPGPDLYSAPIFSSNYSSRSGTAAGAVPPPHPVSHPSPGHNVQGSPHNPSSQLP
Sbjct: 541 TVGRSPGPGPDLYSAPIFSSNYSSRSGTAAGAVPPPHPVSHPSPGHNVQGSPHNPSSQLP 600

Query: 601 PLTAVDAGAERFAPSAPSPHHISPRRVPAPSSILQRTQPPYTQQPSGSHLKSYQPETNSS 660
           PLTAVDAGAERFAPSAPSPHHISPRRVPAPSSILQRTQPPYTQQPSGSHLKSYQPETNSS
Sbjct: 601 PLTAVDAGAERFAPSAPSPHHISPRRVPAPSSILQRTQPPYTQQPSGSHLKSYQPETNSS 660

Query: 661 FQPNGIHVHGFYGQLQKFCPPHYPDSQRIVPPVSSCSVVPSFEDCLVPTSMGQASFDVFH 720
           FQPNGIHVHGFYGQLQKFCPPHYPDSQRIVPPVSSCSVVPSFEDCLVPTSMGQASFDVFH
Sbjct: 661 FQPNGIHVHGFYGQLQKFCPPHYPDSQRIVPPVSSCSVVPSFEDCLVPTSMGQASFDVFH 720

Query: 721 RAFSTHSGITVYDLPSSSSSLFGESLRSGAEDATFLQISTVDRCPSQLSSVYTEG 775
           RAFSTHSGITVYDLPSSSSSLFGESLRSGAEDATFLQISTVDRCPSQLSSVYTEG
Sbjct: 721 RAFSTHSGITVYDLPSSSSSLFGESLRSGAEDATFLQISTVDRCPSQLSSVYTEG 775


>gi|166706915 GLIS family zinc finger 1 [Homo sapiens]
          Length = 620

 Score =  397 bits (1020), Expect = e-110
 Identities = 282/703 (40%), Positives = 336/703 (47%), Gaps = 130/703 (18%)

Query: 99  LPPGTSMSSNSVSNSLPS-YLFGTESSHSPYPSPRHSSTRSHSARSKKRALS-LSPLSDG 156
           L P   +   S++   PS YL G+E S      P          R     L   SP S  
Sbjct: 20  LHPDLDLPGRSLATPAPSCYLLGSEPSSGLGLQPETHLPEGSLKRCCVLGLPPTSPASSS 79

Query: 157 --IGIDFNTIIRTSPTSLVAYINGSRASPANLSPQPEVYGHFLGVRGSCIPQPRPVPGSQ 214
                D  +IIR+S TSLV  +NG R+ P              G  G    + RP P S 
Sbjct: 80  PCASSDVTSIIRSSQTSLVTCVNGLRSPPLT------------GDLGGPSKRARPGPAST 127

Query: 215 KGVLVAPGGLALPAYGEDGALEHERMQQLEHGGLQPGLVNHMVVQHGLPGPDSQSAGLFK 274
                  G L L A  +   L+ E   +                   L GP  Q      
Sbjct: 128 DS---HEGSLQLEACRKASFLKQEPADEFSE----------------LFGPHQQG----- 163

Query: 275 TERLEEFPGSTVDLPPAPPLPPLPPPPGPPPPYHAHAHLHHPELGPHAQQLALPQATLDD 334
                        LPP  PL  LPP                   GP    L L  A    
Sbjct: 164 -------------LPPPYPLSQLPP-------------------GPSLGGLGLGLA---- 187

Query: 335 DGEMDGIGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFN 394
            G +  + G+  CRW+DC A Y+QQEELVRHIEK HIDQRKGEDFTCFWAGC RRYKPFN
Sbjct: 188 -GRV--VAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFN 244

Query: 395 ARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFS 454
           ARYKLLIHMRVHSGEKPNKC FEGC KAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFS
Sbjct: 245 ARYKLLIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFS 304

Query: 455 NSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELH 514
           NSSDRAKHQRTHLDTKPYACQIPGC+KRYTDPSSLRKHVKAHS+KEQQ RKKL +  +  
Sbjct: 305 NSSDRAKHQRTHLDTKPYACQIPGCSKRYTDPSSLRKHVKAHSAKEQQVRKKLHAGPDTE 364

Query: 515 PDLLTDCLTVQSLQPATSPRDAAAEGTVGRSPGPGPDLYSAPIFSSNYSSRSGTAAGAVP 574
            D+LT+CL +Q L   TS + AA++G  G   G G +L    ++  + +  +G A+G +P
Sbjct: 365 ADVLTECLVLQQLH--TSTQLAASDGKGG--CGLGQELLPG-VYPGSITPHNGLASGLLP 419

Query: 575 PPHPVSHPSPGHNVQGSPHNPSSQLPPLTAVDAGAERFAPSAPSPHHISPRRVPAPSSIL 634
           P H V  PS  H +  +  +    L PL   ++  +   P   SP  +SP         L
Sbjct: 420 PAHDV--PSRHHPLDATT-SSHHHLSPLPMAESTRDGLGPGLLSP-IVSP---------L 466

Query: 635 QRTQPPYTQQPSGSHLKSYQPETNSSFQPNGIHVHGFYGQLQKFCPPHYPDSQRIVPPVS 694
           +   PP     S SH    QP      +P+       Y   Q   PP  P  Q       
Sbjct: 467 KGLGPPPLPPSSQSHSPGGQPFPTLPSKPS-------YPPFQSPPPPPLPSPQGYQGSFH 519

Query: 695 SCSVVPSFEDC---LVPTSMGQASFDVFH----------RAFSTHSGITVYD-------- 733
           S      + DC     P + G       H           + ST    T Y+        
Sbjct: 520 SIQSCFPYGDCYRMAEPAAGGDGLVGETHGFNPLRPNGYHSLSTPLPATGYEALAEASCP 579

Query: 734 --LPSSSSSLFGESLRSGAEDATFLQISTVDRCPSQLSSVYTE 774
             LP   S    + + SG ED  F      D C   + S+YT+
Sbjct: 580 TALPQQPSE---DVVSSGPEDCGFFPNGAFDHCLGHIPSIYTD 619


>gi|86991432 GLI-Kruppel family member GLI2 [Homo sapiens]
          Length = 1586

 Score =  275 bits (704), Expect = 9e-74
 Identities = 208/527 (39%), Positives = 257/527 (48%), Gaps = 42/527 (7%)

Query: 126 SPYPSPRHSSTRSHSARSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAYINGSRASPAN 185
           +P    R SS R     S+KRALS+SPLSD   +D   +IRTSP SLVAYIN SR+S A 
Sbjct: 211 NPVDVSRFSSPRVTPRLSRKRALSISPLSDA-SLDLQRMIRTSPNSLVAYINNSRSSSAA 269

Query: 186 LSPQPEVYGHF-LGVRGSCIPQPRPV-PGSQKGVLVAPGGLALPAYGEDGALEHERMQQL 243
                  YGH   G        P P+ P + + +L    GL   A+G    L       L
Sbjct: 270 SGS----YGHLSAGALSPAFTFPHPINPVAYQQILSQQRGLG-SAFGHTPPLIQPSPTFL 324

Query: 244 EHGGLQPGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPPAP---------PL 294
               +    +N    Q       S S  L  T + ++   S V     P           
Sbjct: 325 AQQPMALTSINATPTQLS-----SSSNCLSDTNQNKQSSESAVSSTVNPVAIHKRSKVKT 379

Query: 295 PPLPPPPGPPPPYHAHAHLHHPELG---PHAQ-QLALPQATLDDDG---EMDGIGGKHCC 347
            P    P  P          H   G   P +Q QLA  +  LD D    E + +  +  C
Sbjct: 380 EPEGLRPASPLALTQGQVSGHGSCGCALPLSQEQLADLKEDLDRDDCKQEAEVVIYETNC 439

Query: 348 RWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHS 407
            W DC+  YD QE+LV HI   HI   K E F C W  C R  KPF A+Y L++HMR H+
Sbjct: 440 HWEDCTKEYDTQEQLVHHINNEHIHGEKKE-FVCRWQACTREQKPFKAQYMLVVHMRRHT 498

Query: 408 GEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQ-RTH 466
           GEKP+KCTFEGC KA+SRLENLK HLRSHTGEKPY+C+H GC KAFSN+SDRAKHQ RTH
Sbjct: 499 GEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTH 558

Query: 467 LDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELHPDLLTDCLTVQS 526
            + KPY C+IPGCTKRYTDPSSLRKHVK     +    KK R+   L   LL +    ++
Sbjct: 559 SNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEA 618

Query: 527 LQPATSPRDAAAEGTVGRSPGPGPDLYSAPI---FSSNYSSRSGTAAGAVPPPHPV-SHP 582
                 P    A  T   S      L+   I    S    S  G  +     P P+ S P
Sbjct: 619 GTEPGGPESTEASST---SQAVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAP 675

Query: 583 SPGHNVQGSPHNPSSQLPPLTAVD---AGAERFAPSAPSPHHISPRR 626
           +    V+     P S L  LTA+D    GA+  A +APS   +  R+
Sbjct: 676 NNDSGVEMPGTGPGS-LGDLTALDDTPPGADTSALAAPSAGGLQLRK 721



 Score = 31.6 bits (70), Expect = 2.9
 Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 9/84 (10%)

Query: 568  TAAGAVPPPHPV-SHPSPGHNVQGSPHNPS-SQLPPLTAVDAGAERFAPSAPSPHHISPR 625
            +A   VPPPHPV S+P   H++  S       Q+P L           P    P    P 
Sbjct: 1307 SALAGVPPPHPVQSYPQQSHHLAASMSQEGYHQVPSLLPAR------QPGFMEP-QTGPM 1359

Query: 626  RVPAPSSILQRTQPPYTQQPSGSH 649
             V      L + +PP    P+G H
Sbjct: 1360 GVATAGFGLVQPRPPLEPSPTGRH 1383


>gi|4885279 GLI family zinc finger 1 isoform 1 [Homo sapiens]
          Length = 1106

 Score =  263 bits (671), Expect = 6e-70
 Identities = 165/392 (42%), Positives = 207/392 (52%), Gaps = 63/392 (16%)

Query: 131 PRHSSTRSHSARSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAYINGSRASPANLSPQP 190
           P  SS RS    +KKRALS+SPLSD   +D  T+IRTSP+SLVA+IN    SP       
Sbjct: 66  PLFSSPRSAVKLTKKRALSISPLSDA-SLDLQTVIRTSPSSLVAFINSRCTSPGGS---- 120

Query: 191 EVYGHF-LGVRGSCIPQPRPVPGSQKGVLVAPGGLALPAYGEDGALEHERMQQLEHGGLQ 249
             YGH  +G     +  P  +   QKG          P++G      H+  +    GG+ 
Sbjct: 121 --YGHLSIGTMSPSLGFPAQM-NHQKG--------PSPSFGVQPCGPHDSAR----GGM- 164

Query: 250 PGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPPAPPLPPLPPPPGPPPPYHA 309
                       +P P  QS G F T +L+      V      PL      P        
Sbjct: 165 ------------IPHP--QSRGPFPTCQLKSELDMLVGKCREEPLEGDMSSPNS------ 204

Query: 310 HAHLHHPELGP-------HAQQLALPQATLDDDGEMDGIGGKHCCRWIDCSALYDQQEEL 362
              +  P LG          ++   P++  + D           CRW  CS  +D QE+L
Sbjct: 205 -TGIQDPLLGMLDGREDLEREEKREPESVYETD-----------CRWDGCSQEFDSQEQL 252

Query: 363 VRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCEKA 422
           V HI   HI   + E F C W GC R  +PF A+Y L++HMR H+GEKP+KCTFEGC K+
Sbjct: 253 VHHINSEHIHGERKE-FVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKS 311

Query: 423 FSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQ-RTHLDTKPYACQIPGCTK 481
           +SRLENLK HLRSHTGEKPY+C+H GC KAFSN+SDRAKHQ RTH + KPY C++PGCTK
Sbjct: 312 YSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTK 371

Query: 482 RYTDPSSLRKHVKAHSSKEQQARKKLRSSTEL 513
           RYTDPSSLRKHVK     +    K+ R    L
Sbjct: 372 RYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPL 403


>gi|119393899 GLI-Kruppel family member GLI3 [Homo sapiens]
          Length = 1580

 Score =  261 bits (667), Expect = 2e-69
 Identities = 194/503 (38%), Positives = 243/503 (48%), Gaps = 47/503 (9%)

Query: 120 GTESSHSPY----PSPRHSSTRSHSARSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAY 175
           GT + H  Y     S R SS R  +  S+KR LS+SPLSD    D  T+IRTSP SLV  
Sbjct: 262 GTGAIHMEYLHAMDSTRFSSPRLSARPSRKRTLSISPLSDH-SFDLQTMIRTSPNSLVTI 320

Query: 176 INGSRASPANLSPQPEVYGHFLGVRGSCIPQPRPVPGSQKGVLVAPGGLALPAYGEDGAL 235
           +N SR+S +       +    +    S      PV       +++       A+G    L
Sbjct: 321 LNNSRSSSSASGSYGHLSASAISPALSFTYSSAPVSLHMHQQILSRQQSLGSAFGHSPPL 380

Query: 236 EHERMQ---QLEHGGLQPGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPPAP 292
            H       Q    G+ P ++N + V  G P   SQ+         E    ST D P   
Sbjct: 381 IHPAPTFPTQRPIPGI-PTVLNPVQVSSG-PSESSQNK-----PTSESAVSSTGD-PMHN 432

Query: 293 PLPPLPPPPGPPPPYHAHAHLHHPELGPHAQQLALPQATLDDDGEMDGIGGKHCCRWIDC 352
               + P    P P  A      PE       L   +   D+  +   +  +  C W  C
Sbjct: 433 KRSKIKPDEDLPSP-GARGQQEQPE----GTTLVKEEGDKDESKQEPEVIYETNCHWEGC 487

Query: 353 SALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPN 412
           +  +D QE+LV HI   HI   K E F C W  C R  KPF A+Y L++HMR H+GEKP+
Sbjct: 488 AREFDTQEQLVHHINNDHIHGEKKE-FVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPH 546

Query: 413 KCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQ-RTHLDTKP 471
           KCTFEGC KA+SRLENLK HLRSHTGEKPY+C+H GC KAFSN+SDRAKHQ RTH + KP
Sbjct: 547 KCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 606

Query: 472 YACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELHPDLLTDCLTVQSLQPAT 531
           Y C+IPGCTKRYTDPSSLRKHVK     E    KK R   ++HP                
Sbjct: 607 YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRG--DIHP-------------RPP 651

Query: 532 SPRDAAAEGTVGRSPG-PGPDLYSAPIFSSNYSSRSGTA--AGAVPPPHPV-SHPSPGHN 587
            PRD+ +  +  RSPG P           SN +S+         V    P+ S PSPG  
Sbjct: 652 PPRDSGSH-SQSRSPGRPTQGALGEQQDLSNTTSKREECLQVKTVKAEKPMTSQPSPG-- 708

Query: 588 VQGSPHNPSSQLPPLTAVDAGAE 610
             G     S Q P     ++G E
Sbjct: 709 --GQSSCSSQQSPISNYSNSGLE 729


>gi|229892345 GLI family zinc finger 1 isoform 2 [Homo sapiens]
          Length = 978

 Score =  229 bits (585), Expect = 6e-60
 Identities = 104/168 (61%), Positives = 123/168 (73%), Gaps = 2/168 (1%)

Query: 347 CRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVH 406
           CRW  CS  +D QE+LV HI   HI   + E F C W GC R  +PF A+Y L++HMR H
Sbjct: 109 CRWDGCSQEFDSQEQLVHHINSEHIHGERKE-FVCHWGGCSRELRPFKAQYMLVVHMRRH 167

Query: 407 SGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQ-RT 465
           +GEKP+KCTFEGC K++SRLENLK HLRSHTGEKPY+C+H GC KAFSN+SDRAKHQ RT
Sbjct: 168 TGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRT 227

Query: 466 HLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSSTEL 513
           H + KPY C++PGCTKRYTDPSSLRKHVK     +    K+ R    L
Sbjct: 228 HSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPL 275


>gi|110431364 GLIS family zinc finger 2 [Homo sapiens]
          Length = 524

 Score =  206 bits (523), Expect = 9e-53
 Identities = 94/165 (56%), Positives = 116/165 (70%), Gaps = 5/165 (3%)

Query: 347 CRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVH 406
           CRW  C+ L++  ++LV H+   H+   K   + C W GC R  + FNARYK+LIH+R H
Sbjct: 170 CRWAKCNQLFELLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTH 229

Query: 407 SGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTH 466
           + EKP++C    C K+FSRLENLKIH RSHTGEKPY+C + GC K +SNSSDR KH RTH
Sbjct: 230 TNEKPHRCPT--CSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTH 287

Query: 467 LDTKPYACQIPGCTKRYTDPSSLRKHVKAHS---SKEQQARKKLR 508
              KPY C++PGC KRYTDPSSLRKH+KAH    S EQQ   +LR
Sbjct: 288 YVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLR 332


>gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]
          Length = 663

 Score =  197 bits (500), Expect = 4e-50
 Identities = 103/237 (43%), Positives = 121/237 (51%), Gaps = 38/237 (16%)

Query: 290 PAPPLPPLPPPPGPPPPYHA--HAHLHHPELGPHAQQLALPQATLDDDGEMDGIGGKHCC 347
           P P L    PPP PPPP     H H HHP L P A    L         E+        C
Sbjct: 347 PGPHLQHHAPPPAPPPPPAPAQHPHQHHPHL-PGAAGAFLRYMRQPIKQEL-------IC 398

Query: 348 RWID----------------------------CSALYDQQEELVRHIEKVHIDQRKGEDF 379
           +WID                            CS  +    ELV H+   H+   +    
Sbjct: 399 KWIDPDELAGLPPPPPPPPPPPPPPPAGGAKPCSKTFGTMHELVNHVTVEHVGGPEQSSH 458

Query: 380 TCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGE 439
            CFW  CPR  KPF A+YKL+ H+RVH+GEKP  C F GC K F+R ENLKIH R+HTGE
Sbjct: 459 VCFWEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGE 518

Query: 440 KPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAH 496
           KP+ C+  GC + F+NSSDR KH   H   KPY C+I GC K YT PSSLRKH+K H
Sbjct: 519 KPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIH 575



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 15/18 (83%), Positives = 15/18 (83%)

Query: 289 PPAPPLPPLPPPPGPPPP 306
           PPAPPLPP P PP PPPP
Sbjct: 152 PPAPPLPPTPSPPPPPPP 169



 Score = 37.4 bits (85), Expect = 0.053
 Identities = 13/17 (76%), Positives = 13/17 (76%)

Query: 290 PAPPLPPLPPPPGPPPP 306
           P PP PPLPP P PPPP
Sbjct: 150 PPPPAPPLPPTPSPPPP 166



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 13/23 (56%), Positives = 13/23 (56%)

Query: 282 PGSTVDLPPAPPLPPLPPPPGPP 304
           P     LPP P  PP PPPP PP
Sbjct: 151 PPPAPPLPPTPSPPPPPPPPPPP 173


>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
          Length = 532

 Score =  187 bits (475), Expect = 3e-47
 Identities = 101/250 (40%), Positives = 132/250 (52%), Gaps = 34/250 (13%)

Query: 307 YHAHAHLHHP-ELGPHAQQLALPQATLDDDGEMDGIGGKHCCRWID----------CSAL 355
           +H H H HHP     + +Q  + Q  +              C+WID          C+  
Sbjct: 231 HHHHHHHHHPGAFFRYMRQQCIKQELI--------------CKWIDPEQLSNPKKSCNKT 276

Query: 356 YDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPNKCT 415
           +    ELV H+   H+   +  +  CFW  CPR  KPF A+YKL+ H+RVH+GEKP  C 
Sbjct: 277 FSTMHELVTHVSVEHVGGPEQSNHVCFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCP 336

Query: 416 FEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQ 475
           F GC K F+R ENLKIH R+HTGEKP+ C+  GC + F+NSSDR KH   H   KPY C+
Sbjct: 337 FPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCK 396

Query: 476 IPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSS----TELHPDLLTDCLTVQS---LQ 528
           +  C K YT PSSLRKH+K H S  Q +     +S    +   P L++     QS   L 
Sbjct: 397 M--CDKSYTHPSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGLVSPSAEPQSSSNLS 454

Query: 529 PATSPRDAAA 538
           PA +   AAA
Sbjct: 455 PAAAAAAAAA 464


>gi|22547182 zinc finger protein of the cerebellum 1 [Homo sapiens]
          Length = 447

 Score =  183 bits (465), Expect = 5e-46
 Identities = 90/212 (42%), Positives = 119/212 (56%), Gaps = 15/212 (7%)

Query: 347 CRWID----------CSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNAR 396
           C+WI+          C+  +    ELV H+   H+   +  +  CFW  CPR  KPF A+
Sbjct: 227 CKWIEPEQLANPKKSCNKTFSTMHELVTHVTVEHVGGPEQSNHICFWEECPREGKPFKAK 286

Query: 397 YKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNS 456
           YKL+ H+RVH+GEKP  C F GC K F+R ENLKIH R+HTGEKP+ C+  GC + F+NS
Sbjct: 287 YKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANS 346

Query: 457 SDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELHPD 516
           SDR KH   H   KPY C++  C K YT PSSLRKH+K H S  Q ++    +S+     
Sbjct: 347 SDRKKHMHVHTSDKPYLCKM--CDKSYTHPSSLRKHMKVHESSSQGSQPSPAASSGYESS 404

Query: 517 LLTDCLTVQSLQPAT---SPRDAAAEGTVGRS 545
                ++  +  P T   SP  +A   T G S
Sbjct: 405 TPPTIVSPSTDNPTTSSLSPSSSAVHHTAGHS 436


>gi|22547201 zinc finger protein of the cerebellum 4 [Homo sapiens]
          Length = 334

 Score =  182 bits (463), Expect = 8e-46
 Identities = 102/250 (40%), Positives = 127/250 (50%), Gaps = 38/250 (15%)

Query: 281 FPGSTVDLPPAPPLPPLP--------------PPPGPPPP------YHAHAHLHHPELGP 320
           FPG   + P A P  PL               P P PP P        A A LH    G 
Sbjct: 43  FPGLHEEPPQASPSRPLNGLLRLGLPGDMYARPEPFPPGPAARSDALAAAAALH----GY 98

Query: 321 HAQQLALPQATLDDDGEM-----DGIGGKHCCRWID---------CSALYDQQEELVRHI 366
               L +  A     G         I  +  C+W+          CS  +    ELV H+
Sbjct: 99  GGMNLTVNLAAPHGPGAFFRYMRQPIKQELICKWLAADGTATPSLCSKTFSTMHELVTHV 158

Query: 367 EKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRL 426
              H+   +  +  CFW  CPR+ KPF A+YKL+ H+RVH+GEKP  C F GC K F+R 
Sbjct: 159 TVEHVGGPEQANHICFWEECPRQGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARS 218

Query: 427 ENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDP 486
           ENLKIH R+HTGEKP+ C+  GC++ F+NSSDR KH   H   KPY C++ GC K YT P
Sbjct: 219 ENLKIHKRTHTGEKPFRCEFEGCERRFANSSDRKKHSHVHTSDKPYTCKVRGCDKCYTHP 278

Query: 487 SSLRKHVKAH 496
           SSLRKH+K H
Sbjct: 279 SSLRKHMKVH 288


>gi|4507973 zinc finger protein of the cerebellum 3 [Homo sapiens]
          Length = 467

 Score =  176 bits (446), Expect = 7e-44
 Identities = 87/215 (40%), Positives = 116/215 (53%), Gaps = 16/215 (7%)

Query: 347 CRWID----------CSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNAR 396
           C+WID          C   +    ELV H+   H+   +  +  C+W  CPR  K F A+
Sbjct: 253 CKWIDEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWEECPREGKSFKAK 312

Query: 397 YKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNS 456
           YKL+ H+RVH+GEKP  C F GC K F+R ENLKIH R+HTGEKP+ C+  GC + F+NS
Sbjct: 313 YKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANS 372

Query: 457 SDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELHPD 516
           SDR KH   H   KPY C++  C K YT PSSLRKH+K H S+   +     S  E    
Sbjct: 373 SDRKKHMHVHTSDKPYICKV--CDKSYTHPSSLRKHMKVHESQGSDSSPAASSGYESS-- 428

Query: 517 LLTDCLTVQSLQPATSPRDAAAEGTVGRSPGPGPD 551
             T      +    T+   +A + +   +PG  P+
Sbjct: 429 --TPPAIASANSKDTTKTPSAVQTSTSHNPGLPPN 461


>gi|116014328 zinc finger protein 143 [Homo sapiens]
          Length = 638

 Score =  124 bits (310), Expect = 4e-28
 Identities = 63/186 (33%), Positives = 96/186 (51%), Gaps = 7/186 (3%)

Query: 368 KVHIDQRKGED-FTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRL 426
           K H+    GE  + C    C + +K      K   H+R H+GE+P KC FEGC ++F+  
Sbjct: 285 KSHVRTHTGEKPYRCSEDNCTKSFKTSGDLQK---HIRTHTGERPFKCPFEGCGRSFTTS 341

Query: 427 ENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDP 486
              K+H+R+HTGE+PY C  PGC +AF+++++   H R H   KPY C +PGC KR+T+ 
Sbjct: 342 NIRKVHVRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRFTEY 401

Query: 487 SSLRKHVKAHSSKEQQARKKLRSSTELHPDLLTDCLTVQSLQPATSPRDAAAEGTVGRSP 546
           SSL KH   H+  +           + +  + T  +  ++    T P +   E      P
Sbjct: 402 SSLYKHHVVHTHSKPY---NCNHCGKTYKQISTLAMHKRTAHNDTEPIEEEQEAFFEPPP 458

Query: 547 GPGPDL 552
           G G D+
Sbjct: 459 GQGEDV 464



 Score =  114 bits (285), Expect = 3e-25
 Identities = 55/154 (35%), Positives = 84/154 (54%), Gaps = 7/154 (4%)

Query: 347 CRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVH 406
           C +  C  LY     L  H E+ H   R    + C  AGC    K F   Y L  H+R H
Sbjct: 239 CEYDGCGKLYTTAHHLKVH-ERSHTGDRP---YQCEHAGCG---KAFATGYGLKSHVRTH 291

Query: 407 SGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTH 466
           +GEKP +C+ + C K+F    +L+ H+R+HTGE+P+ C   GC ++F+ S+ R  H RTH
Sbjct: 292 TGEKPYRCSEDNCTKSFKTSGDLQKHIRTHTGERPFKCPFEGCGRSFTTSNIRKVHVRTH 351

Query: 467 LDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKE 500
              +PY C  PGC + +   ++ + HV+ H+ ++
Sbjct: 352 TGERPYYCTEPGCGRAFASATNYKNHVRIHTGEK 385



 Score =  100 bits (248), Expect = 7e-21
 Identities = 40/93 (43%), Positives = 57/93 (61%)

Query: 407 SGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTH 466
           SGEK  +C ++GC K ++   +LK+H RSHTG++PY C+H GC KAF+       H RTH
Sbjct: 232 SGEKAFRCEYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHAGCGKAFATGYGLKSHVRTH 291

Query: 467 LDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSK 499
              KPY C    CTK +     L+KH++ H+ +
Sbjct: 292 TGEKPYRCSEDNCTKSFKTSGDLQKHIRTHTGE 324



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 25/89 (28%), Positives = 45/89 (50%), Gaps = 6/89 (6%)

Query: 437 TGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAH 496
           +GEK + C++ GC K ++ +     H+R+H   +PY C+  GC K +     L+ HV+ H
Sbjct: 232 SGEKAFRCEYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHAGCGKAFATGYGLKSHVRTH 291

Query: 497 SSK------EQQARKKLRSSTELHPDLLT 519
           + +      E    K  ++S +L   + T
Sbjct: 292 TGEKPYRCSEDNCTKSFKTSGDLQKHIRT 320


>gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]
          Length = 753

 Score =  117 bits (294), Expect = 3e-26
 Identities = 104/341 (30%), Positives = 141/341 (41%), Gaps = 50/341 (14%)

Query: 347 CRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVH 406
           C    C   +     L  H+ +VH    K + F C   GC    K FN  Y+L  H R+H
Sbjct: 172 CNQEGCGKAFLTSYSLRIHV-RVHT---KEKPFECDVQGCE---KAFNTLYRLKAHQRLH 224

Query: 407 SGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTH 466
           +G+  N C  EGC K F+ L +L+ H+R+HTGEKP+ C H GC KAF+ S     H RTH
Sbjct: 225 TGKTFN-CESEGCSKYFTTLSDLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTH 283

Query: 467 LDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSK--EQQARKKLRSSTELHPDLLTDCLTV 524
              +P+ C   GC K ++   SL+ H+K H +K     A  +   S + +  L   CL+ 
Sbjct: 284 TGERPFFCPSNGCEKTFSTQYSLKSHMKGHDNKGHSYNALPQHNGSEDTNHSL---CLSD 340

Query: 525 QSLQPATSPRDAAAEGTVGRSPGPGPDLYSAPIFSSNYSSRSGTAAGAVP---------- 574
            SL    S     +  T G+       +  A IF S + +   TA    P          
Sbjct: 341 LSLLSTDSELRENSSTTQGQDLS---TISPAIIFESMFQNSDDTAIQEDPQQTASLTESF 397

Query: 575 --PPHPVSH--PSPGHNVQGS---PHNPSSQLPPLTAVDAGAERFAPSAPS--------- 618
                 VS   PS G++   S      P    PP   + A A    P APS         
Sbjct: 398 NGDAESVSDVPPSTGNSASLSLPLVLQPGLSEPPQPLLPASAPSAPPPAPSLGPGSQQAA 457

Query: 619 ----PHHISPRRVPAPSSILQRTQPPYTQQPSGSHLKSYQP 655
               P  + P  VP P S    TQ     Q    H ++ QP
Sbjct: 458 FGNPPALLQPPEVPVPHS----TQFAANHQEFLPHPQAPQP 494



 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 68/288 (23%), Positives = 105/288 (36%), Gaps = 41/288 (14%)

Query: 333 DDDGEMDG-----IGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCP 387
           DDDG+        +GG+     ID  A+     + +   +++H+    G          P
Sbjct: 62  DDDGQCGEHLPFLVGGEEGFHLIDHEAMSQGYVQHIISPDQIHLTINPGS------TPMP 115

Query: 388 RRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHP 447
           R  +      +           K  +CTFEGC + +S   NL+ H ++H GE  ++C   
Sbjct: 116 RNIEGATLTLQSECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQE 175

Query: 448 GCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSK----EQQA 503
           GC KAF  S     H R H   KP+ C + GC K +     L+ H + H+ K    E + 
Sbjct: 176 GCGKAFLTSYSLRIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTGKTFNCESEG 235

Query: 504 RKKLRSSTELHPDLLTDCLTVQSLQPATSPRDAAAEG-------------TVGRSPGPGP 550
             K  ++     DL     T    +P     D   +                G  P   P
Sbjct: 236 CSKYFTTLS---DLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCP 292

Query: 551 DLYSAPIFSSNYSSRSGTAAGAVPPPHPVSHPSPGHNVQGSPHNPSSQ 598
                  FS+ YS +S          H   H + GH+    P +  S+
Sbjct: 293 SNGCEKTFSTQYSLKS----------HMKGHDNKGHSYNALPQHNGSE 330


>gi|133922582 zinc finger protein 358 [Homo sapiens]
          Length = 568

 Score =  115 bits (289), Expect = 1e-25
 Identities = 94/292 (32%), Positives = 120/292 (41%), Gaps = 46/292 (15%)

Query: 352 CSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKP 411
           C+  + Q   L++H+ + H  +R           CP+  K F     LL H R H+ E+P
Sbjct: 268 CAKGFGQGSALLKHL-RTHTGERPYP--------CPQCGKAFGQSSALLQHQRTHTAERP 318

Query: 412 NKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKP 471
            +C    C KAF +  NL+ HLR HTGE+PY C H  C KAF  SS   +H   H   +P
Sbjct: 319 YRCPH--CGKAFGQSSNLQHHLRIHTGERPYACPH--CSKAFGQSSALLQHLHVHSGERP 374

Query: 472 YACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELHPDLLTDCLTVQSLQPAT 531
           Y CQ+  C K +   SSL KH + H      A     ++      L         L P  
Sbjct: 375 YRCQL--CGKAFGQASSLTKHKRVHEGAAAAAAAAAAAAAAAAAGL--------GLGPGL 424

Query: 532 SPRDAAAEGTVGRSPGPGPDLYSAPIFSSNYSSRSGTAAGAVPP--------PHPVSHPS 583
           SP      G V      GPD  S  +  S      GT++G  P         P P S P 
Sbjct: 425 SPASMMRPGQVSLL---GPDAVS--VLGSGLGLSPGTSSGRNPDPGSGPGTLPDPSSKPL 479

Query: 584 PGHNVQGSPHNPSSQLPPLTAVDAGAERFAPS-----APSPHHISPRRVPAP 630
           PG     SP  P     P    DAG +   PS      PSP    P  VP+P
Sbjct: 480 PGSRSTPSP-TPVESSDPKAGHDAGPD-LVPSPDLDPVPSP---DPDPVPSP 526



 Score = 86.7 bits (213), Expect = 8e-17
 Identities = 73/238 (30%), Positives = 97/238 (40%), Gaps = 30/238 (12%)

Query: 263 PGPDSQSAGLFKTERLEEFPGSTVDLPPAPPLPPLPPPPGPPPPYHAHAHLHHPELG-PH 321
           P  D+ S G  K + +     +T  +    P   LP P  PP P+        P+ G   
Sbjct: 108 PNSDTLSPGDPKVDPISSGLTATPQVLATSPAV-LPAPASPPRPFSC------PDCGRAF 160

Query: 322 AQQLALPQATLDDDGEMDGIGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTC 381
            +   L Q      GE          R  DC   +     L +H   +H   R    + C
Sbjct: 161 RRSSGLSQHRRTHSGEKP-------YRCPDCGKSFSHGATLAQH-RGIHTGARP---YQC 209

Query: 382 FWAGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKP 441
              G     K F  R  LL H   HSGEKP+ C    C KAF     L  HLR+H G +P
Sbjct: 210 AACG-----KAFGWRSTLLKHRSSHSGEKPHHCPV--CGKAFGHGSLLAQHLRTHGGPRP 262

Query: 442 YLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSK 499
           + C  P C K F   S   KH RTH   +PY C  P C K +   S+L +H + H+++
Sbjct: 263 HKC--PVCAKGFGQGSALLKHLRTHTGERPYPC--PQCGKAFGQSSALLQHQRTHTAE 316



 Score = 66.6 bits (161), Expect = 8e-11
 Identities = 34/90 (37%), Positives = 49/90 (54%), Gaps = 4/90 (4%)

Query: 411 PNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTK 470
           P   +   C +AF R   L  H R+H+GEKPY C  P C K+FS+ +  A+H+  H   +
Sbjct: 148 PRPFSCPDCGRAFRRSSGLSQHRRTHSGEKPYRC--PDCGKSFSHGATLAQHRGIHTGAR 205

Query: 471 PYACQIPGCTKRYTDPSSLRKHVKAHSSKE 500
           PY C    C K +   S+L KH  +HS ++
Sbjct: 206 PYQC--AACGKAFGWRSTLLKHRSSHSGEK 233


>gi|90193619 nuclear matrix transcription factor 4 isoform c [Homo
           sapiens]
          Length = 461

 Score =  114 bits (285), Expect = 3e-25
 Identities = 64/167 (38%), Positives = 89/167 (53%), Gaps = 17/167 (10%)

Query: 333 DDDGEMDGIGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKP 392
           DDD + DG    + CR   CS  +  + E+  H  K H + +  +        CP   K 
Sbjct: 163 DDDHQKDG--KTYRCRM--CSLTFYSKSEMQIH-SKSHTETKPHK--------CPHCSKT 209

Query: 393 FNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKA 452
           F     L  H+R+HSG KP  C F  CEK+F +L +L+ H R HTG++PY C HPGC+KA
Sbjct: 210 FANSSYLAQHIRIHSGAKPYSCNF--CEKSFRQLSHLQQHTRIHTGDRPYKCAHPGCEKA 267

Query: 453 FSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSK 499
           F+  S+   H+R H   KP+ C    C + YTD +SL  H+  H+ K
Sbjct: 268 FTQLSNLQSHRRQHNKDKPFKCH--NCHRAYTDAASLEVHLSTHTVK 312


>gi|90193617 nuclear matrix transcription factor 4 isoform b [Homo
           sapiens]
          Length = 500

 Score =  114 bits (285), Expect = 3e-25
 Identities = 64/167 (38%), Positives = 89/167 (53%), Gaps = 17/167 (10%)

Query: 333 DDDGEMDGIGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKP 392
           DDD + DG    + CR   CS  +  + E+  H  K H + +  +        CP   K 
Sbjct: 202 DDDHQKDG--KTYRCRM--CSLTFYSKSEMQIH-SKSHTETKPHK--------CPHCSKT 248

Query: 393 FNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKA 452
           F     L  H+R+HSG KP  C F  CEK+F +L +L+ H R HTG++PY C HPGC+KA
Sbjct: 249 FANSSYLAQHIRIHSGAKPYSCNF--CEKSFRQLSHLQQHTRIHTGDRPYKCAHPGCEKA 306

Query: 453 FSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSK 499
           F+  S+   H+R H   KP+ C    C + YTD +SL  H+  H+ K
Sbjct: 307 FTQLSNLQSHRRQHNKDKPFKCH--NCHRAYTDAASLEVHLSTHTVK 351


>gi|90193615 nuclear matrix transcription factor 4 isoform b [Homo
           sapiens]
          Length = 500

 Score =  114 bits (285), Expect = 3e-25
 Identities = 64/167 (38%), Positives = 89/167 (53%), Gaps = 17/167 (10%)

Query: 333 DDDGEMDGIGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKP 392
           DDD + DG    + CR   CS  +  + E+  H  K H + +  +        CP   K 
Sbjct: 202 DDDHQKDG--KTYRCRM--CSLTFYSKSEMQIH-SKSHTETKPHK--------CPHCSKT 248

Query: 393 FNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKA 452
           F     L  H+R+HSG KP  C F  CEK+F +L +L+ H R HTG++PY C HPGC+KA
Sbjct: 249 FANSSYLAQHIRIHSGAKPYSCNF--CEKSFRQLSHLQQHTRIHTGDRPYKCAHPGCEKA 306

Query: 453 FSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSK 499
           F+  S+   H+R H   KP+ C    C + YTD +SL  H+  H+ K
Sbjct: 307 FTQLSNLQSHRRQHNKDKPFKCH--NCHRAYTDAASLEVHLSTHTVK 351


>gi|90193613 nuclear matrix transcription factor 4 isoform a [Homo
           sapiens]
          Length = 516

 Score =  114 bits (285), Expect = 3e-25
 Identities = 64/167 (38%), Positives = 89/167 (53%), Gaps = 17/167 (10%)

Query: 333 DDDGEMDGIGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKP 392
           DDD + DG    + CR   CS  +  + E+  H  K H + +  +        CP   K 
Sbjct: 218 DDDHQKDG--KTYRCRM--CSLTFYSKSEMQIH-SKSHTETKPHK--------CPHCSKT 264

Query: 393 FNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKA 452
           F     L  H+R+HSG KP  C F  CEK+F +L +L+ H R HTG++PY C HPGC+KA
Sbjct: 265 FANSSYLAQHIRIHSGAKPYSCNF--CEKSFRQLSHLQQHTRIHTGDRPYKCAHPGCEKA 322

Query: 453 FSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSK 499
           F+  S+   H+R H   KP+ C    C + YTD +SL  H+  H+ K
Sbjct: 323 FTQLSNLQSHRRQHNKDKPFKCH--NCHRAYTDAASLEVHLSTHTVK 367


>gi|90193611 nuclear matrix transcription factor 4 isoform a [Homo
           sapiens]
          Length = 516

 Score =  114 bits (285), Expect = 3e-25
 Identities = 64/167 (38%), Positives = 89/167 (53%), Gaps = 17/167 (10%)

Query: 333 DDDGEMDGIGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKP 392
           DDD + DG    + CR   CS  +  + E+  H  K H + +  +        CP   K 
Sbjct: 218 DDDHQKDG--KTYRCRM--CSLTFYSKSEMQIH-SKSHTETKPHK--------CPHCSKT 264

Query: 393 FNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKA 452
           F     L  H+R+HSG KP  C F  CEK+F +L +L+ H R HTG++PY C HPGC+KA
Sbjct: 265 FANSSYLAQHIRIHSGAKPYSCNF--CEKSFRQLSHLQQHTRIHTGDRPYKCAHPGCEKA 322

Query: 453 FSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSK 499
           F+  S+   H+R H   KP+ C    C + YTD +SL  H+  H+ K
Sbjct: 323 FTQLSNLQSHRRQHNKDKPFKCH--NCHRAYTDAASLEVHLSTHTVK 367


>gi|36054194 nuclear matrix transcription factor 4 isoform a [Homo
           sapiens]
          Length = 516

 Score =  114 bits (285), Expect = 3e-25
 Identities = 64/167 (38%), Positives = 89/167 (53%), Gaps = 17/167 (10%)

Query: 333 DDDGEMDGIGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKP 392
           DDD + DG    + CR   CS  +  + E+  H  K H + +  +        CP   K 
Sbjct: 218 DDDHQKDG--KTYRCRM--CSLTFYSKSEMQIH-SKSHTETKPHK--------CPHCSKT 264

Query: 393 FNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKA 452
           F     L  H+R+HSG KP  C F  CEK+F +L +L+ H R HTG++PY C HPGC+KA
Sbjct: 265 FANSSYLAQHIRIHSGAKPYSCNF--CEKSFRQLSHLQQHTRIHTGDRPYKCAHPGCEKA 322

Query: 453 FSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSK 499
           F+  S+   H+R H   KP+ C    C + YTD +SL  H+  H+ K
Sbjct: 323 FTQLSNLQSHRRQHNKDKPFKCH--NCHRAYTDAASLEVHLSTHTVK 367


>gi|21361146 zinc finger protein 76 (expressed in testis) [Homo
           sapiens]
          Length = 570

 Score =  113 bits (283), Expect = 6e-25
 Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 4/131 (3%)

Query: 368 KVHIDQRKGED-FTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRL 426
           K H+    GE  + C    C + +K      K   H+R H+GE+P +C FEGC ++F+  
Sbjct: 213 KSHVRTHTGEKPYKCPEELCSKAFKTSGDLQK---HVRTHTGERPFQCPFEGCGRSFTTS 269

Query: 427 ENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDP 486
              K+H+R+HTGE+PY C  P C + F+++++   H R H   KPY C +PGC KR+T+ 
Sbjct: 270 NIRKVHVRTHTGERPYTCPEPHCGRGFTSATNYKNHVRIHTGEKPYVCTVPGCGKRFTEY 329

Query: 487 SSLRKHVKAHS 497
           SSL KH   H+
Sbjct: 330 SSLYKHHVVHT 340



 Score =  111 bits (278), Expect = 2e-24
 Identities = 56/154 (36%), Positives = 82/154 (53%), Gaps = 7/154 (4%)

Query: 347 CRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVH 406
           C +  C  LY     L  H E+ H   R    + C +  C    K F   Y L  H+R H
Sbjct: 167 CGYKGCGRLYTTAHHLKVH-ERAHTGDRP---YRCDFPSCG---KAFATGYGLKSHVRTH 219

Query: 407 SGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTH 466
           +GEKP KC  E C KAF    +L+ H+R+HTGE+P+ C   GC ++F+ S+ R  H RTH
Sbjct: 220 TGEKPYKCPEELCSKAFKTSGDLQKHVRTHTGERPFQCPFEGCGRSFTTSNIRKVHVRTH 279

Query: 467 LDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKE 500
              +PY C  P C + +T  ++ + HV+ H+ ++
Sbjct: 280 TGERPYTCPEPHCGRGFTSATNYKNHVRIHTGEK 313



 Score =  102 bits (253), Expect = 2e-21
 Identities = 56/150 (37%), Positives = 75/150 (50%), Gaps = 10/150 (6%)

Query: 352 CSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKP 411
           CS  +    +L +H+ + H  +R    F C + GC R +   N R    +H+R H+GE+P
Sbjct: 232 CSKAFKTSGDLQKHV-RTHTGERP---FQCPFEGCGRSFTTSNIRK---VHVRTHTGERP 284

Query: 412 NKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKP 471
             C    C + F+   N K H+R HTGEKPY+C  PGC K F+  S   KH   H   KP
Sbjct: 285 YTCPEPHCGRGFTSATNYKNHVRIHTGEKPYVCTVPGCGKRFTEYSSLYKHHVVHTHCKP 344

Query: 472 YACQIPGCTKRYTDPSSLRKHVK-AHSSKE 500
           Y C    C K Y   S+L  H + AH   E
Sbjct: 345 YTCST--CGKTYRQTSTLAMHKRSAHGELE 372



 Score = 86.7 bits (213), Expect = 8e-17
 Identities = 34/92 (36%), Positives = 54/92 (58%)

Query: 408 GEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHL 467
           G++  +C ++GC + ++   +LK+H R+HTG++PY C  P C KAF+       H RTH 
Sbjct: 161 GDRAFRCGYKGCGRLYTTAHHLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHVRTHT 220

Query: 468 DTKPYACQIPGCTKRYTDPSSLRKHVKAHSSK 499
             KPY C    C+K +     L+KHV+ H+ +
Sbjct: 221 GEKPYKCPEELCSKAFKTSGDLQKHVRTHTGE 252



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 22/88 (25%), Positives = 42/88 (47%), Gaps = 6/88 (6%)

Query: 438 GEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHS 497
           G++ + C + GC + ++ +     H+R H   +PY C  P C K +     L+ HV+ H+
Sbjct: 161 GDRAFRCGYKGCGRLYTTAHHLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHVRTHT 220

Query: 498 SK------EQQARKKLRSSTELHPDLLT 519
            +      E+   K  ++S +L   + T
Sbjct: 221 GEKPYKCPEELCSKAFKTSGDLQKHVRT 248


>gi|38570115 zinc finger protein 362 [Homo sapiens]
          Length = 420

 Score =  112 bits (279), Expect = 2e-24
 Identities = 55/119 (46%), Positives = 76/119 (63%), Gaps = 6/119 (5%)

Query: 386 CPRRYKPF-NARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLC 444
           CP   K F NA Y L  H+R+H G KP  C++  C+K+F +L +L+ H R HTG++PY C
Sbjct: 257 CPHCSKSFANASY-LAQHLRIHLGVKPYHCSY--CDKSFRQLSHLQQHTRIHTGDRPYKC 313

Query: 445 QHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKEQQA 503
            HPGC+KAF+  S+   HQR H   KPY C  P C + Y+D +SL+ H+ AH+ K  +A
Sbjct: 314 PHPGCEKAFTQLSNLQSHQRQHNKDKPYKC--PNCYRAYSDSASLQIHLSAHAIKHAKA 370



 Score = 87.8 bits (216), Expect = 3e-17
 Identities = 50/151 (33%), Positives = 76/151 (50%), Gaps = 15/151 (9%)

Query: 352 CSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKP 411
           CS  +     L +H+ ++H+  +    + C +       K F     L  H R+H+G++P
Sbjct: 260 CSKSFANASYLAQHL-RIHLGVKP---YHCSYCD-----KSFRQLSHLQQHTRIHTGDRP 310

Query: 412 NKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHL--DT 469
            KC   GCEKAF++L NL+ H R H  +KPY C  P C +A+S+S+    H   H     
Sbjct: 311 YKCPHPGCEKAFTQLSNLQSHQRQHNKDKPYKC--PNCYRAYSDSASLQIHLSAHAIKHA 368

Query: 470 KPYACQIPGCTKRYTDPSSLRKHVKAHSSKE 500
           K Y C +  C + YT  + L KH+  H+  E
Sbjct: 369 KAYCCSM--CGRAYTSETYLMKHMSKHTVVE 397



 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 31/79 (39%), Positives = 44/79 (55%), Gaps = 4/79 (5%)

Query: 419 CEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPG 478
           C   F     ++IH +SHT  KP+ C H  C K+F+N+S  A+H R HL  KPY C    
Sbjct: 232 CPLTFFTKSEMQIHSKSHTEAKPHKCPH--CSKSFANASYLAQHLRIHLGVKPYHCSY-- 287

Query: 479 CTKRYTDPSSLRKHVKAHS 497
           C K +   S L++H + H+
Sbjct: 288 CDKSFRQLSHLQQHTRIHT 306


>gi|64368880 zinc finger and SCAN domain containing 25 [Homo
           sapiens]
          Length = 544

 Score =  110 bits (274), Expect = 6e-24
 Identities = 74/233 (31%), Positives = 114/233 (48%), Gaps = 42/233 (18%)

Query: 279 EEFPGSTVDLPPAPPLPPLPPPPGPPPPYHAHAHLHH--------PELGP---HAQQLAL 327
           E+ PG      PA   P LPPP     P       H         PE G     +  L  
Sbjct: 311 EQEPGG-----PAGSAPGLPPPQHGAIPLPDEVKTHSSFWKPFQCPECGKGFSRSSNLVR 365

Query: 328 PQATLDDDGEMDGIGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCP 387
            Q T ++          + C  ++C   +  +E L++H ++ H+ +R           C 
Sbjct: 366 HQRTHEEKS--------YGC--VECGKGFTLREYLMKH-QRTHLGKRPYV--------CS 406

Query: 388 RRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHP 447
             +K F+ R+ L +H R H+GEKP KC    C K+FSR ++L++H R+HTGEKPY C+  
Sbjct: 407 ECWKTFSQRHHLEVHQRSHTGEKPYKCG--DCWKSFSRRQHLQVHRRTHTGEKPYTCE-- 462

Query: 448 GCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKE 500
            C K+FS +++ A H+R H   KPY CQ+  C KR++    L +H + H+ ++
Sbjct: 463 -CGKSFSRNANLAVHRRAHTGEKPYGCQV--CGKRFSKGERLVRHQRIHTGEK 512



 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 42/121 (34%), Positives = 61/121 (50%), Gaps = 14/121 (11%)

Query: 351 DCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEK 410
           DC   + +++ L  H  + H  ++    +TC         K F+    L +H R H+GEK
Sbjct: 435 DCWKSFSRRQHLQVH-RRTHTGEKP---YTCECG------KSFSRNANLAVHRRAHTGEK 484

Query: 411 PNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTK 470
           P  C  + C K FS+ E L  H R HTGEKPY C  P C ++F+  S   +HQ+T    +
Sbjct: 485 PYGC--QVCGKRFSKGERLVRHQRIHTGEKPYHC--PACGRSFNQRSILNRHQKTQHRQE 540

Query: 471 P 471
           P
Sbjct: 541 P 541


>gi|209180475 nuclear matrix transcription factor 4 isoform d [Homo
           sapiens]
          Length = 577

 Score =  109 bits (273), Expect = 8e-24
 Identities = 64/196 (32%), Positives = 94/196 (47%), Gaps = 17/196 (8%)

Query: 308 HAHAHLH-HPELGPHAQQLALPQATLDDDGEMDGIGGKHCCRWIDCSALYDQQEELVRHI 366
           H+ +H    P   PH  +     + L     +      + C +  C   + Q   L +H 
Sbjct: 246 HSKSHTETKPHKCPHCSKTFANSSYLAQHIRIHSGAKPYSCNF--CEKSFRQLSHLQQHT 303

Query: 367 E---KVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCEKAF 423
               K+H +  K          CP   K F     L  H+R+HSG KP  C++  C+KAF
Sbjct: 304 RIHSKMHTETIKPHK-------CPHCSKTFANTSYLAQHLRIHSGAKPYNCSY--CQKAF 354

Query: 424 SRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRY 483
            +L +L+ H R HTG++PY C HPGC+KAF+  S+   H+R H   KP+ C    C + Y
Sbjct: 355 RQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKPFKCH--NCHRAY 412

Query: 484 TDPSSLRKHVKAHSSK 499
           TD +SL  H+  H+ K
Sbjct: 413 TDAASLEVHLSTHTVK 428



 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 45/150 (30%), Positives = 70/150 (46%), Gaps = 16/150 (10%)

Query: 353 SALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPN 412
           S L +  +  V   E     Q+ G+ + C           F ++ ++ IH + H+  KP+
Sbjct: 202 SGLPEMNDPYVLSPEDDDDHQKDGKTYRCRMCSLT-----FYSKSEMQIHSKSHTETKPH 256

Query: 413 KCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHL----- 467
           KC    C K F+    L  H+R H+G KPY C    C+K+F   S   +H R H      
Sbjct: 257 KCPH--CSKTFANSSYLAQHIRIHSGAKPYSCNF--CEKSFRQLSHLQQHTRIHSKMHTE 312

Query: 468 DTKPYACQIPGCTKRYTDPSSLRKHVKAHS 497
             KP+ C  P C+K + + S L +H++ HS
Sbjct: 313 TIKPHKC--PHCSKTFANTSYLAQHLRIHS 340



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 33/87 (37%), Positives = 45/87 (51%), Gaps = 4/87 (4%)

Query: 419 CEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPG 478
           C   F     ++IH +SHT  KP+ C H  C K F+NSS  A+H R H   KPY+C    
Sbjct: 233 CSLTFYSKSEMQIHSKSHTETKPHKCPH--CSKTFANSSYLAQHIRIHSGAKPYSCNF-- 288

Query: 479 CTKRYTDPSSLRKHVKAHSSKEQQARK 505
           C K +   S L++H + HS    +  K
Sbjct: 289 CEKSFRQLSHLQQHTRIHSKMHTETIK 315


>gi|122937229 zinc finger protein 629 [Homo sapiens]
          Length = 869

 Score =  108 bits (271), Expect = 1e-23
 Identities = 62/150 (41%), Positives = 83/150 (55%), Gaps = 15/150 (10%)

Query: 351 DCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEK 410
           +C   + Q   LV+H ++ H  ++  +        CP   K F+    L+ H R H+GEK
Sbjct: 182 ECGKSFTQSSHLVQH-QRTHTGEKPYK--------CPDCGKCFSWSSNLVQHQRTHTGEK 232

Query: 411 PNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTK 470
           P KCT   CEKAF++  NL  H RSHTGEKPY C    C++AF  SSD  +HQ TH   K
Sbjct: 233 PYKCT--ECEKAFTQSTNLIKHQRSHTGEKPYKCGE--CRRAFYRSSDLIQHQATHTGEK 288

Query: 471 PYACQIPGCTKRYTDPSSLRKHVKAHSSKE 500
           PY C  P C KR+    +L KH K H+ ++
Sbjct: 289 PYKC--PECGKRFGQNHNLLKHQKIHAGEK 316



 Score =  101 bits (251), Expect = 3e-21
 Identities = 57/148 (38%), Positives = 81/148 (54%), Gaps = 6/148 (4%)

Query: 386 CPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQ 445
           C    K F+   KLL H R+H+GE+PN C+   C K+F++  +L  H R+HTGEKPY C 
Sbjct: 152 CNECGKSFSQWSKLLRHQRIHTGERPNTCS--ECGKSFTQSSHLVQHQRTHTGEKPYKC- 208

Query: 446 HPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARK 505
            P C K FS SS+  +HQRTH   KPY C    C K +T  ++L KH ++H+ ++     
Sbjct: 209 -PDCGKCFSWSSNLVQHQRTHTGEKPYKC--TECEKAFTQSTNLIKHQRSHTGEKPYKCG 265

Query: 506 KLRSSTELHPDLLTDCLTVQSLQPATSP 533
           + R +     DL+    T    +P   P
Sbjct: 266 ECRRAFYRSSDLIQHQATHTGEKPYKCP 293



 Score = 97.8 bits (242), Expect = 3e-20
 Identities = 53/149 (35%), Positives = 81/149 (54%), Gaps = 15/149 (10%)

Query: 351 DCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEK 410
           +C   + +  +L++H +  H  ++  +        CP   K F   + LL H ++H+GEK
Sbjct: 266 ECRRAFYRSSDLIQH-QATHTGEKPYK--------CPECGKRFGQNHNLLKHQKIHAGEK 316

Query: 411 PNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTK 470
           P +CT   C K+F +   L  H R+HTGEKPY C    C K+F +SS   KHQRTHL   
Sbjct: 317 PYRCT--ECGKSFIQSSELTQHQRTHTGEKPYECLE--CGKSFGHSSTLIKHQRTHLRED 372

Query: 471 PYACQIPGCTKRYTDPSSLRKHVKAHSSK 499
           P+ C  P C K +T  ++L +H + H+ +
Sbjct: 373 PFKC--PVCGKTFTLSATLLRHQRTHTGE 399



 Score = 93.2 bits (230), Expect = 8e-19
 Identities = 71/234 (30%), Positives = 98/234 (41%), Gaps = 24/234 (10%)

Query: 351 DCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEK 410
           +C   +     L+ H +++H  +R    + C   G     K F     L+ H R+H+GEK
Sbjct: 406 ECGKSFSVSSNLINH-QRIHRGERP---YICADCG-----KSFIMSSTLIRHQRIHTGEK 456

Query: 411 PNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTK 470
           P KC+   C K+F R  +L  H R+HTGEKPY C  P C K+FS SS+   H RTH+D  
Sbjct: 457 PYKCS--DCGKSFIRSSHLIQHRRTHTGEKPYKC--PECGKSFSQSSNLITHVRTHMDEN 512

Query: 471 PYACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSST--ELHPDLLTDCLTVQSLQ 528
            + C    C K + +   L +H   H   +  AR+    S      P LLT         
Sbjct: 513 LFVCS--DCGKAFLEAHELEQHRVIHERGKTPARRAQGDSLLGLGDPSLLTP-------P 563

Query: 529 PATSPRDAAAEGTVGRSPGPGPDLYSAPIFSSNYSSRSGTAAGAVPPPHPVSHP 582
           P   P      G      G         I  + Y +  G  A A P P  +  P
Sbjct: 564 PGAKPHKCLVCGKGFNDEGIFMQHQRIHIGENPYKNADGLIAHAAPKPPQLRSP 617



 Score = 84.0 bits (206), Expect = 5e-16
 Identities = 53/158 (33%), Positives = 75/158 (47%), Gaps = 15/158 (9%)

Query: 343 GKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIH 402
           G+   R  +C   + Q  EL +H ++ H  ++  E   C         K F     L+ H
Sbjct: 314 GEKPYRCTECGKSFIQSSELTQH-QRTHTGEKPYECLECG--------KSFGHSSTLIKH 364

Query: 403 MRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKH 462
            R H  E P KC    C K F+    L  H R+HTGE+PY C  P C K+FS SS+   H
Sbjct: 365 QRTHLREDPFKCPV--CGKTFTLSATLLRHQRTHTGERPYKC--PECGKSFSVSSNLINH 420

Query: 463 QRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKE 500
           QR H   +PY C    C K +   S+L +H + H+ ++
Sbjct: 421 QRIHRGERPYIC--ADCGKSFIMSSTLIRHQRIHTGEK 456



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 6/86 (6%)

Query: 386 CPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQ 445
           CP   + F    +LL+H +VH+G K ++ + E  + +   LE    HLRS  G +PY C 
Sbjct: 716 CPECKQSFGLSSELLLHQKVHAGGKSSQKSPELGKSSSVLLE----HLRSPLGARPYRCS 771

Query: 446 HPGCQKAFSNSSDRAKHQRTHLDTKP 471
              C+ +F +     +HQ TH   KP
Sbjct: 772 --DCRASFLDRVALTRHQETHTQEKP 795



 Score = 30.0 bits (66), Expect = 8.5
 Identities = 25/103 (24%), Positives = 39/103 (37%), Gaps = 25/103 (24%)

Query: 434 RSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPY--------------------- 472
           R     K Y+C H  C ++F + S   +HQ TH + KP+                     
Sbjct: 654 RGLLSSKTYICSH--CGESFLDRSVLLQHQLTHGNEKPFLFPDYRIGLGEGAGPSPFLSG 711

Query: 473 -ACQIPGCTKRYTDPSSLRKHVKAHS-SKEQQARKKLRSSTEL 513
              + P C + +   S L  H K H+  K  Q   +L  S+ +
Sbjct: 712 KPFKCPECKQSFGLSSELLLHQKVHAGGKSSQKSPELGKSSSV 754


>gi|55769561 zinc finger protein 21 isoform 2 [Homo sapiens]
          Length = 620

 Score =  107 bits (268), Expect = 3e-23
 Identities = 62/160 (38%), Positives = 84/160 (52%), Gaps = 15/160 (9%)

Query: 351 DCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEK 410
           +C   + Q+  L+ H ++ H +++    + C   G     K F  + KL+IH R+H+GEK
Sbjct: 471 ECEKAFSQKSYLIIH-QRTHTEEKP---YKCNECG-----KAFREKSKLIIHQRIHTGEK 521

Query: 411 PNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTK 470
           P +C    C KAFS+   L IH R+HTGEKPY C    C KAF   S    HQRTH   K
Sbjct: 522 PYECPV--CWKAFSQKSQLIIHQRTHTGEKPYACTE--CGKAFREKSTFTVHQRTHTGEK 577

Query: 471 PYACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSS 510
           PY C    C K +T  S+L  H + H+ K+   R   R S
Sbjct: 578 PYKC--TECGKAFTQKSNLIVHQRTHAGKKAHGRGHTRKS 615



 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 56/150 (37%), Positives = 79/150 (52%), Gaps = 15/150 (10%)

Query: 351 DCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEK 410
           +C   ++++  L+ H ++ H  ++  E   C         K F  +  L +H R HSGEK
Sbjct: 387 ECGKSFNEKSTLIVH-QRTHTGEKPYECDVCG--------KTFTQKSNLGVHQRTHSGEK 437

Query: 411 PNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTK 470
           P +C    CEKAFS+   L +H R HTGEKPY C    C+KAFS  S    HQRTH + K
Sbjct: 438 PFECN--ECEKAFSQKSYLMLHQRGHTGEKPYECNE--CEKAFSQKSYLIIHQRTHTEEK 493

Query: 471 PYACQIPGCTKRYTDPSSLRKHVKAHSSKE 500
           PY C    C K + + S L  H + H+ ++
Sbjct: 494 PYKCN--ECGKAFREKSKLIIHQRIHTGEK 521



 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 51/115 (44%), Positives = 65/115 (56%), Gaps = 6/115 (5%)

Query: 386 CPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQ 445
           C    K F+ +  L++H R H+GEKP  CT   C KAFS+   L IHLR+HTGE+P+ C 
Sbjct: 217 CTACRKTFSKKSHLIVHWRTHTGEKPFGCT--ECGKAFSQKSQLIIHLRTHTGERPFEC- 273

Query: 446 HPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKE 500
            P C KAF   S    H RTH   KPY C    C K +T  S+L  H K H+ ++
Sbjct: 274 -PECGKAFREKSTVIIHYRTHTGEKPYECN--ECGKAFTQKSNLIVHQKTHTGEK 325



 Score = 94.0 bits (232), Expect = 5e-19
 Identities = 53/149 (35%), Positives = 77/149 (51%), Gaps = 15/149 (10%)

Query: 352 CSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKP 411
           C   + Q+ +L+ H    H  ++  E        C    K F+ +  L+IH R H+GEKP
Sbjct: 332 CGESFIQKLDLIIH-HSTHTGKKPHE--------CNECKKTFSDKSTLIIHQRTHTGEKP 382

Query: 412 NKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKP 471
           +KCT   C K+F+    L +H R+HTGEKPY C    C K F+  S+   HQRTH   KP
Sbjct: 383 HKCT--ECGKSFNEKSTLIVHQRTHTGEKPYECD--VCGKTFTQKSNLGVHQRTHSGEKP 438

Query: 472 YACQIPGCTKRYTDPSSLRKHVKAHSSKE 500
           + C    C K ++  S L  H + H+ ++
Sbjct: 439 FECN--ECEKAFSQKSYLMLHQRGHTGEK 465



 Score = 91.7 bits (226), Expect = 2e-18
 Identities = 50/150 (33%), Positives = 78/150 (52%), Gaps = 15/150 (10%)

Query: 351 DCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEK 410
           +C   + Q+ +L+ H+ + H  +R  E        CP   K F  +  ++IH R H+GEK
Sbjct: 247 ECGKAFSQKSQLIIHL-RTHTGERPFE--------CPECGKAFREKSTVIIHYRTHTGEK 297

Query: 411 PNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTK 470
           P +C    C KAF++  NL +H ++HTGEK Y C    C ++F    D   H  TH   K
Sbjct: 298 PYECN--ECGKAFTQKSNLIVHQKTHTGEKTYECTK--CGESFIQKLDLIIHHSTHTGKK 353

Query: 471 PYACQIPGCTKRYTDPSSLRKHVKAHSSKE 500
           P+ C    C K ++D S+L  H + H+ ++
Sbjct: 354 PHECN--ECKKTFSDKSTLIIHQRTHTGEK 381



 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 45/116 (38%), Positives = 62/116 (53%), Gaps = 6/116 (5%)

Query: 385 GCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLC 444
           GC    K F+ + +L+IH+R H+GE+P +C    C KAF     + IH R+HTGEKPY C
Sbjct: 244 GCTECGKAFSQKSQLIIHLRTHTGERPFEC--PECGKAFREKSTVIIHYRTHTGEKPYEC 301

Query: 445 QHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKE 500
               C KAF+  S+   HQ+TH   K Y C    C + +     L  H   H+ K+
Sbjct: 302 NE--CGKAFTQKSNLIVHQKTHTGEKTYEC--TKCGESFIQKLDLIIHHSTHTGKK 353



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 9/109 (8%)

Query: 394 NARYKLLIHM---RVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQ 450
           N   KL  H    + + G KP    ++ C K   R + L +H R   GEKP+ C    C+
Sbjct: 166 NGCAKLFFHTEYEKTNPGMKPYG--YKECGKGLRRKKGLSLHQRIKNGEKPFEC--TACR 221

Query: 451 KAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSK 499
           K FS  S    H RTH   KP+ C    C K ++  S L  H++ H+ +
Sbjct: 222 KTFSKKSHLIVHWRTHTGEKPFGC--TECGKAFSQKSQLIIHLRTHTGE 268


>gi|55769559 zinc finger protein 21 isoform 1 [Homo sapiens]
          Length = 639

 Score =  107 bits (268), Expect = 3e-23
 Identities = 62/160 (38%), Positives = 84/160 (52%), Gaps = 15/160 (9%)

Query: 351 DCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEK 410
           +C   + Q+  L+ H ++ H +++    + C   G     K F  + KL+IH R+H+GEK
Sbjct: 490 ECEKAFSQKSYLIIH-QRTHTEEKP---YKCNECG-----KAFREKSKLIIHQRIHTGEK 540

Query: 411 PNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTK 470
           P +C    C KAFS+   L IH R+HTGEKPY C    C KAF   S    HQRTH   K
Sbjct: 541 PYECPV--CWKAFSQKSQLIIHQRTHTGEKPYACTE--CGKAFREKSTFTVHQRTHTGEK 596

Query: 471 PYACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSS 510
           PY C    C K +T  S+L  H + H+ K+   R   R S
Sbjct: 597 PYKC--TECGKAFTQKSNLIVHQRTHAGKKAHGRGHTRKS 634



 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 56/150 (37%), Positives = 79/150 (52%), Gaps = 15/150 (10%)

Query: 351 DCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEK 410
           +C   ++++  L+ H ++ H  ++  E   C         K F  +  L +H R HSGEK
Sbjct: 406 ECGKSFNEKSTLIVH-QRTHTGEKPYECDVCG--------KTFTQKSNLGVHQRTHSGEK 456

Query: 411 PNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTK 470
           P +C    CEKAFS+   L +H R HTGEKPY C    C+KAFS  S    HQRTH + K
Sbjct: 457 PFECN--ECEKAFSQKSYLMLHQRGHTGEKPYECNE--CEKAFSQKSYLIIHQRTHTEEK 512

Query: 471 PYACQIPGCTKRYTDPSSLRKHVKAHSSKE 500
           PY C    C K + + S L  H + H+ ++
Sbjct: 513 PYKCN--ECGKAFREKSKLIIHQRIHTGEK 540



 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 51/115 (44%), Positives = 65/115 (56%), Gaps = 6/115 (5%)

Query: 386 CPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQ 445
           C    K F+ +  L++H R H+GEKP  CT   C KAFS+   L IHLR+HTGE+P+ C 
Sbjct: 236 CTACRKTFSKKSHLIVHWRTHTGEKPFGCT--ECGKAFSQKSQLIIHLRTHTGERPFEC- 292

Query: 446 HPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKE 500
            P C KAF   S    H RTH   KPY C    C K +T  S+L  H K H+ ++
Sbjct: 293 -PECGKAFREKSTVIIHYRTHTGEKPYECN--ECGKAFTQKSNLIVHQKTHTGEK 344



 Score = 94.0 bits (232), Expect = 5e-19
 Identities = 53/149 (35%), Positives = 77/149 (51%), Gaps = 15/149 (10%)

Query: 352 CSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKP 411
           C   + Q+ +L+ H    H  ++  E        C    K F+ +  L+IH R H+GEKP
Sbjct: 351 CGESFIQKLDLIIH-HSTHTGKKPHE--------CNECKKTFSDKSTLIIHQRTHTGEKP 401

Query: 412 NKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKP 471
           +KCT   C K+F+    L +H R+HTGEKPY C    C K F+  S+   HQRTH   KP
Sbjct: 402 HKCT--ECGKSFNEKSTLIVHQRTHTGEKPYECD--VCGKTFTQKSNLGVHQRTHSGEKP 457

Query: 472 YACQIPGCTKRYTDPSSLRKHVKAHSSKE 500
           + C    C K ++  S L  H + H+ ++
Sbjct: 458 FECN--ECEKAFSQKSYLMLHQRGHTGEK 484



 Score = 91.7 bits (226), Expect = 2e-18
 Identities = 50/150 (33%), Positives = 78/150 (52%), Gaps = 15/150 (10%)

Query: 351 DCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEK 410
           +C   + Q+ +L+ H+ + H  +R  E        CP   K F  +  ++IH R H+GEK
Sbjct: 266 ECGKAFSQKSQLIIHL-RTHTGERPFE--------CPECGKAFREKSTVIIHYRTHTGEK 316

Query: 411 PNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTK 470
           P +C    C KAF++  NL +H ++HTGEK Y C    C ++F    D   H  TH   K
Sbjct: 317 PYECN--ECGKAFTQKSNLIVHQKTHTGEKTYECTK--CGESFIQKLDLIIHHSTHTGKK 372

Query: 471 PYACQIPGCTKRYTDPSSLRKHVKAHSSKE 500
           P+ C    C K ++D S+L  H + H+ ++
Sbjct: 373 PHECN--ECKKTFSDKSTLIIHQRTHTGEK 400



 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 45/116 (38%), Positives = 62/116 (53%), Gaps = 6/116 (5%)

Query: 385 GCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLC 444
           GC    K F+ + +L+IH+R H+GE+P +C    C KAF     + IH R+HTGEKPY C
Sbjct: 263 GCTECGKAFSQKSQLIIHLRTHTGERPFEC--PECGKAFREKSTVIIHYRTHTGEKPYEC 320

Query: 445 QHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKE 500
               C KAF+  S+   HQ+TH   K Y C    C + +     L  H   H+ K+
Sbjct: 321 NE--CGKAFTQKSNLIVHQKTHTGEKTYEC--TKCGESFIQKLDLIIHHSTHTGKK 372



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 9/109 (8%)

Query: 394 NARYKLLIHM---RVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQ 450
           N   KL  H    + + G KP    ++ C K   R + L +H R   GEKP+ C    C+
Sbjct: 185 NGCAKLFFHTEYEKTNPGMKPYG--YKECGKGLRRKKGLSLHQRIKNGEKPFEC--TACR 240

Query: 451 KAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSK 499
           K FS  S    H RTH   KP+ C    C K ++  S L  H++ H+ +
Sbjct: 241 KTFSKKSHLIVHWRTHTGEKPFGC--TECGKAFSQKSQLIIHLRTHTGE 287


>gi|223468648 zinc finger protein 389 [Homo sapiens]
          Length = 269

 Score =  105 bits (262), Expect = 2e-22
 Identities = 62/156 (39%), Positives = 83/156 (53%), Gaps = 15/156 (9%)

Query: 351 DCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEK 410
           +C   + Q   LVRH +++H  ++  E        C    K F+ R  L +H R+H+GEK
Sbjct: 48  ECGKKFAQSSGLVRH-QRIHTGEKPYE--------CDHYGKAFSVRSTLTVHERIHTGEK 98

Query: 411 PNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTK 470
           P  C    C+KAFS   +L IH R H GEKPY C    C KAFS SSD  KHQR H   K
Sbjct: 99  PYTCN--ECKKAFSVRAHLIIHQRIHNGEKPYECNE--CGKAFSVSSDLIKHQRIHTGEK 154

Query: 471 PYACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKK 506
           PY C    C K ++  S+L KH + H+ ++    K+
Sbjct: 155 PYECD--ECGKAFSVSSALIKHQRIHTGEKPYEYKE 188



 Score = 87.4 bits (215), Expect = 5e-17
 Identities = 52/147 (35%), Positives = 74/147 (50%), Gaps = 15/147 (10%)

Query: 351 DCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEK 410
           +C   +    +L++H +++H  ++  E        C    K F+    L+ H R+H+GEK
Sbjct: 132 ECGKAFSVSSDLIKH-QRIHTGEKPYE--------CDECGKAFSVSSALIKHQRIHTGEK 182

Query: 411 PNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTK 470
           P +  ++ C KAF     L  H R H+GEKPY C    C KAFS  S    HQR H   K
Sbjct: 183 PYE--YKECGKAFYVNSALINHQRIHSGEKPYECGE--CGKAFSQISTLIHHQRIHTGEK 238

Query: 471 PYACQIPGCTKRYTDPSSLRKHVKAHS 497
           PY C+   C K +   S+L KH K H+
Sbjct: 239 PYECE--ECGKAFHGSSNLTKHQKTHA 263



 Score = 80.9 bits (198), Expect = 4e-15
 Identities = 46/120 (38%), Positives = 63/120 (52%), Gaps = 13/120 (10%)

Query: 351 DCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEK 410
           +C   +     L++H +++H  ++  E   C         K F     L+ H R+HSGEK
Sbjct: 160 ECGKAFSVSSALIKH-QRIHTGEKPYEYKECG--------KAFYVNSALINHQRIHSGEK 210

Query: 411 PNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTK 470
           P +C    C KAFS++  L  H R HTGEKPY C+   C KAF  SS+  KHQ+TH   K
Sbjct: 211 PYECG--ECGKAFSQISTLIHHQRIHTGEKPYECEE--CGKAFHGSSNLTKHQKTHAKGK 266


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,481,416
Number of Sequences: 37866
Number of extensions: 2513154
Number of successful extensions: 56625
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1298
Number of HSP's successfully gapped in prelim test: 737
Number of HSP's that attempted gapping in prelim test: 15563
Number of HSP's gapped (non-prelim): 15151
length of query: 775
length of database: 18,247,518
effective HSP length: 110
effective length of query: 665
effective length of database: 14,082,258
effective search space: 9364701570
effective search space used: 9364701570
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.