Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 14249584
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14249584 hematopoietic SH2 domain containing [Homo sapiens]
(352 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14249584 hematopoietic SH2 domain containing [Homo sapiens] 726 0.0
gi|157820785 SH2 domain containing 7 [Homo sapiens] 102 7e-22
gi|239787762 SH2 domain protein 2A isoform 4 [Homo sapiens] 96 6e-20
gi|239787758 SH2 domain protein 2A isoform 3 [Homo sapiens] 96 6e-20
gi|239787750 SH2 domain protein 2A isoform 2 [Homo sapiens] 96 6e-20
gi|239787783 SH2 domain protein 2A isoform 2 [Homo sapiens] 96 6e-20
gi|239787752 SH2 domain protein 2A isoform 1 [Homo sapiens] 87 2e-17
gi|21361891 SH2 domain containing 4A [Homo sapiens] 79 5e-15
gi|4758476 GRB2-related adaptor protein 2 [Homo sapiens] 55 7e-08
gi|18250298 src-related kinase lacking C-terminal regulatory tyr... 54 3e-07
gi|4503787 fyn-related kinase [Homo sapiens] 48 2e-05
gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens] 47 3e-05
gi|5174647 PTK6 protein tyrosine kinase 6 [Homo sapiens] 46 4e-05
gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a... 46 6e-05
gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b... 46 6e-05
gi|58219064 Src homology 2 domain containing E [Homo sapiens] 46 6e-05
gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-lik... 45 1e-04
gi|205277435 spleen tyrosine kinase isoform 2 [Homo sapiens] 45 1e-04
gi|21361553 spleen tyrosine kinase isoform 1 [Homo sapiens] 45 1e-04
gi|219842230 feline sarcoma oncogene isoform 2 [Homo sapiens] 45 1e-04
gi|4503687 feline sarcoma oncogene isoform 1 [Homo sapiens] 45 1e-04
gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens] 45 1e-04
gi|153266778 arg tyrosine kinase isoform c [Homo sapiens] 44 2e-04
gi|6382062 arg tyrosine kinase isoform b [Homo sapiens] 44 2e-04
gi|209862778 arg tyrosine kinase isoform e [Homo sapiens] 44 2e-04
gi|209862772 arg tyrosine kinase isoform d [Homo sapiens] 44 2e-04
gi|153266757 arg tyrosine kinase isoform a [Homo sapiens] 44 2e-04
gi|52630425 NCK adaptor protein 2 isoform A [Homo sapiens] 44 2e-04
gi|52630423 NCK adaptor protein 2 isoform A [Homo sapiens] 44 2e-04
gi|148596974 TXK tyrosine kinase [Homo sapiens] 44 2e-04
>gi|14249584 hematopoietic SH2 domain containing [Homo sapiens]
Length = 352
Score = 726 bits (1873), Expect = 0.0
Identities = 352/352 (100%), Positives = 352/352 (100%)
Query: 1 MTEAGKLPLPLPPRLDWFVHTQMGQLAQDGVPEWFHGAISREDAENLLESQPLGSFLIRV 60
MTEAGKLPLPLPPRLDWFVHTQMGQLAQDGVPEWFHGAISREDAENLLESQPLGSFLIRV
Sbjct: 1 MTEAGKLPLPLPPRLDWFVHTQMGQLAQDGVPEWFHGAISREDAENLLESQPLGSFLIRV 60
Query: 61 SHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRREL 120
SHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRREL
Sbjct: 61 SHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRREL 120
Query: 121 LTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEEASPKPVLCHQSKERKPSAEMNR 180
LTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEEASPKPVLCHQSKERKPSAEMNR
Sbjct: 121 LTQPCRQKDPANVDYEDLFLYSNAVAEEAACPVSAPEEASPKPVLCHQSKERKPSAEMNR 180
Query: 181 ITTKEATSSCPPKSPLGETRQKLWRSLKMLPERGQRVRQQLKSHLATVNLSSLLDVRRST 240
ITTKEATSSCPPKSPLGETRQKLWRSLKMLPERGQRVRQQLKSHLATVNLSSLLDVRRST
Sbjct: 181 ITTKEATSSCPPKSPLGETRQKLWRSLKMLPERGQRVRQQLKSHLATVNLSSLLDVRRST 240
Query: 241 VISGPGTGKGSQDHSGDPTSGDRGYTDPCVATSLKSPSQPQAPKDRKVPTRKAERSVSCI 300
VISGPGTGKGSQDHSGDPTSGDRGYTDPCVATSLKSPSQPQAPKDRKVPTRKAERSVSCI
Sbjct: 241 VISGPGTGKGSQDHSGDPTSGDRGYTDPCVATSLKSPSQPQAPKDRKVPTRKAERSVSCI 300
Query: 301 EVTPGDRSWHQMVVRALSSQESKPEHQGLAEPENDQLPEEYQQPPPFAPGYC 352
EVTPGDRSWHQMVVRALSSQESKPEHQGLAEPENDQLPEEYQQPPPFAPGYC
Sbjct: 301 EVTPGDRSWHQMVVRALSSQESKPEHQGLAEPENDQLPEEYQQPPPFAPGYC 352
>gi|157820785 SH2 domain containing 7 [Homo sapiens]
Length = 451
Score = 102 bits (253), Expect = 7e-22
Identities = 66/200 (33%), Positives = 101/200 (50%), Gaps = 11/200 (5%)
Query: 15 LDWFVHTQMGQLAQDG-VPEWFHGAISREDAENLLESQPLGSFLIRVSHSHVGYTLSYKA 73
L WF+ TQ + Q+G +P WFHG I+R+ E LL + LGSFLIR+S GY LSY+
Sbjct: 31 LKWFMETQAPFILQNGALPPWFHGFITRKQTEQLLRDKALGSFLIRLSDRATGYILSYRG 90
Query: 74 QSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRRELLTQPC-RQKDPAN 132
C HF++ L + ++I G+ +H++L LV +Q+ +EP +E+LT C R +D
Sbjct: 91 SDRCRHFVINQLRNRRYIISGDTQSHSTLAELVHHYQEAQLEPFKEMLTAACPRPEDNDL 150
Query: 133 VDYEDLFLYSNAVAEE----AACPVSAPEEA-----SPKPVLCHQSKERKPSAEMNRITT 183
D L+ V E A P++A SPKP + ++ ++
Sbjct: 151 YDAITRGLHQTIVDPENPPATAFLTVVPDKAASPRSSPKPQVSFLHAQKSLDVSPRNLSQ 210
Query: 184 KEATSSCPPKSPLGETRQKL 203
+E+ + SPL E L
Sbjct: 211 EESMEAPIRVSPLPEKSSSL 230
>gi|239787762 SH2 domain protein 2A isoform 4 [Homo sapiens]
Length = 361
Score = 95.5 bits (236), Expect = 6e-20
Identities = 47/115 (40%), Positives = 68/115 (59%), Gaps = 1/115 (0%)
Query: 17 WFVHTQMGQLAQDGV-PEWFHGAISREDAENLLESQPLGSFLIRVSHSHVGYTLSYKAQS 75
WF TQ L Q G P WFHG I+R +AE LLE +P G +L+R S S V + L+Y++++
Sbjct: 49 WFQKTQAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRT 108
Query: 76 SCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRRELLTQPCRQKDP 130
C HF++ L DG ++ GE AH L L+ + P+ P E LT+P ++ P
Sbjct: 109 CCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTP 163
>gi|239787758 SH2 domain protein 2A isoform 3 [Homo sapiens]
Length = 371
Score = 95.5 bits (236), Expect = 6e-20
Identities = 47/115 (40%), Positives = 68/115 (59%), Gaps = 1/115 (0%)
Query: 17 WFVHTQMGQLAQDGV-PEWFHGAISREDAENLLESQPLGSFLIRVSHSHVGYTLSYKAQS 75
WF TQ L Q G P WFHG I+R +AE LLE +P G +L+R S S V + L+Y++++
Sbjct: 59 WFQKTQAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRT 118
Query: 76 SCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRRELLTQPCRQKDP 130
C HF++ L DG ++ GE AH L L+ + P+ P E LT+P ++ P
Sbjct: 119 CCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTP 173
>gi|239787750 SH2 domain protein 2A isoform 2 [Homo sapiens]
Length = 389
Score = 95.5 bits (236), Expect = 6e-20
Identities = 47/115 (40%), Positives = 68/115 (59%), Gaps = 1/115 (0%)
Query: 17 WFVHTQMGQLAQDGV-PEWFHGAISREDAENLLESQPLGSFLIRVSHSHVGYTLSYKAQS 75
WF TQ L Q G P WFHG I+R +AE LLE +P G +L+R S S V + L+Y++++
Sbjct: 77 WFQKTQAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRT 136
Query: 76 SCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRRELLTQPCRQKDP 130
C HF++ L DG ++ GE AH L L+ + P+ P E LT+P ++ P
Sbjct: 137 CCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTP 191
>gi|239787783 SH2 domain protein 2A isoform 2 [Homo sapiens]
Length = 389
Score = 95.5 bits (236), Expect = 6e-20
Identities = 47/115 (40%), Positives = 68/115 (59%), Gaps = 1/115 (0%)
Query: 17 WFVHTQMGQLAQDGV-PEWFHGAISREDAENLLESQPLGSFLIRVSHSHVGYTLSYKAQS 75
WF TQ L Q G P WFHG I+R +AE LLE +P G +L+R S S V + L+Y++++
Sbjct: 77 WFQKTQAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRT 136
Query: 76 SCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRRELLTQPCRQKDP 130
C HF++ L DG ++ GE AH L L+ + P+ P E LT+P ++ P
Sbjct: 137 CCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTP 191
>gi|239787752 SH2 domain protein 2A isoform 1 [Homo sapiens]
Length = 399
Score = 87.4 bits (215), Expect = 2e-17
Identities = 47/125 (37%), Positives = 68/125 (54%), Gaps = 11/125 (8%)
Query: 17 WFVHTQMGQLAQDGV-PEWFHGAISRE----------DAENLLESQPLGSFLIRVSHSHV 65
WF TQ L Q G P WFHG I+R +AE LLE +P G +L+R S S V
Sbjct: 77 WFQKTQAHWLLQHGAAPAWFHGFITRRVRPPLSVTHREAERLLEPKPQGCYLVRFSESAV 136
Query: 66 GYTLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRRELLTQPC 125
+ L+Y++++ C HF++ L DG ++ GE AH L L+ + P+ P E LT+P
Sbjct: 137 TFVLTYRSRTCCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPL 196
Query: 126 RQKDP 130
++ P
Sbjct: 197 ARQTP 201
>gi|21361891 SH2 domain containing 4A [Homo sapiens]
Length = 454
Score = 79.3 bits (194), Expect = 5e-15
Identities = 48/130 (36%), Positives = 70/130 (53%), Gaps = 8/130 (6%)
Query: 17 WFVHTQMG-----QLAQDGVPEWFHGAISREDAENLLESQPL-GSFLIRVSHSHVGYTLS 70
WF Q+ Q D + WFHG ++ + A LL S + GSFLIRVS GY LS
Sbjct: 325 WFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKGYALS 384
Query: 71 YKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEP-RRELLTQPCRQKD 129
Y ++ C HF++ D + +++ H +L LV +H+++PI +ELL PC Q+D
Sbjct: 385 YLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQQD 444
Query: 130 PANVDYEDLF 139
DY +LF
Sbjct: 445 QL-PDYLELF 453
>gi|4758476 GRB2-related adaptor protein 2 [Homo sapiens]
Length = 330
Score = 55.5 bits (132), Expect = 7e-08
Identities = 31/99 (31%), Positives = 55/99 (55%), Gaps = 3/99 (3%)
Query: 32 PEWFHGAISREDAENLLESQPLGSFLIRVSHSHVG-YTLSYKAQSSCCHFMVKLLDDGTF 90
P+WFH +SR AENLL + +G F+IR S S G +++S + + HF V + G +
Sbjct: 56 PKWFHEGLSRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115
Query: 91 MIPGEKVAHTSLDALVTFHQQKPIEPRRELLTQPCRQKD 129
+ EK SL+ LV +++ I ++++ + ++D
Sbjct: 116 FLWTEK--FPSLNKLVDYYRTNSISRQKQIFLRDRTRED 152
>gi|18250298 src-related kinase lacking C-terminal regulatory
tyrosine and N-terminal myristylation sites [Homo
sapiens]
Length = 488
Score = 53.5 bits (127), Expect = 3e-07
Identities = 37/101 (36%), Positives = 57/101 (56%), Gaps = 6/101 (5%)
Query: 34 WFHGAISREDAENLLESQPL--GSFLIRVSHSHVG-YTLSYKAQSSCCHFMVKLLDDGTF 90
W+ +SR A+ LL S P G+FLIR S S +G Y+LS +AQ+ CH+ V + DG+
Sbjct: 120 WYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGYSLSVRAQAKVCHYRVSMAADGSL 179
Query: 91 MIPGEKVAHTSLDALVTFHQQKPIEPRRELLTQPCR-QKDP 130
+ ++ L+ L+T+++ + LL QPC QK P
Sbjct: 180 YLQKGRL-FPGLEELLTYYKANWKLIQNPLL-QPCMPQKAP 218
>gi|4503787 fyn-related kinase [Homo sapiens]
Length = 505
Score = 47.8 bits (112), Expect = 2e-05
Identities = 35/95 (36%), Positives = 48/95 (50%), Gaps = 5/95 (5%)
Query: 34 WFHGAISREDAEN--LLESQPLGSFLIRVSHSHVG-YTLSYKAQSSCCHFMVKLLDDGTF 90
WF GAI R DAE L GSFLIR S S G ++LS + H+ +K LD+G F
Sbjct: 116 WFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRIKRLDEGGF 175
Query: 91 MIPGEKVAHTSLDALVTFHQQKPIEPRRELLTQPC 125
+ ++ T L+ V+ H K + L +PC
Sbjct: 176 FLTRRRIFST-LNEFVS-HYTKTSDGLCVKLGKPC 208
>gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens]
Length = 822
Score = 47.0 bits (110), Expect = 3e-05
Identities = 41/180 (22%), Positives = 77/180 (42%), Gaps = 21/180 (11%)
Query: 33 EWFHGAISREDAENLLESQPLGSFLIRVSHSHVG-YTLSYKAQSSCCHFMVKLLDDGTFM 91
+W+HGAI R +A+ LL+ Q G FL+R SH G Y LS + HF+++ +D+ M
Sbjct: 459 DWYHGAIPRIEAQELLKKQ--GDFLVRESHGKPGEYVLSVYSDGQRRHFIIQYVDN---M 513
Query: 92 IPGEKVAHTSLDALVTFH---QQKPIEPRRELLTQPCRQKDPANVDYEDLFL-------- 140
E +++ L+ H +Q + +L P + + +ED+ L
Sbjct: 514 YRFEGTGFSNIPQLIDHHYTTKQVITKKSGVVLLNPIPKDKKWILSHEDVILGELLGKGN 573
Query: 141 ----YSNAVAEEAACPVSAPEEASPKPVLCHQSKERKPSAEMNRITTKEATSSCPPKSPL 196
Y + ++ + V +E P+ + +E K + + + C + P+
Sbjct: 574 FGEVYKGTLKDKTSVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPV 633
>gi|5174647 PTK6 protein tyrosine kinase 6 [Homo sapiens]
Length = 451
Score = 46.2 bits (108), Expect = 4e-05
Identities = 34/107 (31%), Positives = 50/107 (46%), Gaps = 5/107 (4%)
Query: 34 WFHGAISREDAENLL--ESQPLGSFLIRVSHS-HVGYTLSYKAQSSCCHFMVKLLDDGTF 90
WF G ISR +A L E G+FLIRVS Y LS + + H+ + G
Sbjct: 78 WFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQAVRHYKIWRRAGGRL 137
Query: 91 MIPGEKVAHTSLDALVTFHQQKPIEPRRELLTQPCRQKDPANVDYED 137
+ E V+ SL LV +H+ + + L PCR+ +P + + D
Sbjct: 138 HL-NEAVSFLSLPELVNYHRAQSLSHGLR-LAAPCRKHEPEPLPHWD 182
>gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a
[Homo sapiens]
Length = 1130
Score = 45.8 bits (107), Expect = 6e-05
Identities = 28/77 (36%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Query: 34 WFHGAISREDAENLLESQPLGSFLIRVSHSHVGY-TLSYKAQSSCCHFMVKLLDDGTFMI 92
W+HG +SR AE LL S GSFL+R S S G ++S + + H+ + DG +
Sbjct: 127 WYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYV 186
Query: 93 PGEKVAHTSLDALVTFH 109
E +T L LV H
Sbjct: 187 SSESRFNT-LAELVHHH 202
>gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b
[Homo sapiens]
Length = 1149
Score = 45.8 bits (107), Expect = 6e-05
Identities = 28/77 (36%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Query: 34 WFHGAISREDAENLLESQPLGSFLIRVSHSHVGY-TLSYKAQSSCCHFMVKLLDDGTFMI 92
W+HG +SR AE LL S GSFL+R S S G ++S + + H+ + DG +
Sbjct: 146 WYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYV 205
Query: 93 PGEKVAHTSLDALVTFH 109
E +T L LV H
Sbjct: 206 SSESRFNT-LAELVHHH 221
>gi|58219064 Src homology 2 domain containing E [Homo sapiens]
Length = 495
Score = 45.8 bits (107), Expect = 6e-05
Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 5/96 (5%)
Query: 24 GQLAQDGVP----EWFHGAISREDAENLLESQPLGSFLIRVSHS-HVGYTLSYKAQSSCC 78
G+ G+P W+HGAISR +AE+ L+ +L+R S S + Y+++ K C
Sbjct: 381 GEKVDPGLPLEKQPWYHGAISRAEAESRLQPCKEAGYLVRNSESGNSRYSIALKTSQGCV 440
Query: 79 HFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPI 114
H +V D + + S+ +V ++ + +
Sbjct: 441 HIIVAQTKDNKYTLNQTSAVFDSIPEVVHYYSNEKL 476
>gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-like
[Homo sapiens]
Length = 303
Score = 45.1 bits (105), Expect = 1e-04
Identities = 26/78 (33%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Query: 34 WFHGAISREDAENLLESQPLGSFLIRVSHSHVG-YTLSYKAQSSCCHFMVKLLDDGTFMI 92
W+ G +SR++A+ L+ Q G FL+R S + G Y LS S H+++ L + F I
Sbjct: 14 WYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKI 73
Query: 93 PGEKVAHTSLDALVTFHQ 110
++ H L AL+ F++
Sbjct: 74 GDQEFDH--LPALLEFYK 89
>gi|205277435 spleen tyrosine kinase isoform 2 [Homo sapiens]
Length = 612
Score = 44.7 bits (104), Expect = 1e-04
Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 9/117 (7%)
Query: 13 PRLDWFVHTQMGQLAQDGVPEWFHGAISREDAEN--LLESQPLGSFLIRVSHSHVGYTLS 70
P+L+ + T A + +P WFHG ISRE++E L+ S+ G FLIR ++ Y L
Sbjct: 152 PQLEKLIATT----AHEKMP-WFHGKISREESEQIVLIGSKTNGKFLIRARDNNGSYALC 206
Query: 71 YKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRRELLTQPCRQ 127
+ H+ + G IP K T L LV + K + +LT PC++
Sbjct: 207 LLHEGKVLHYRIDKDKTGKLSIPEGKKFDT-LWQLVEHYSYK-ADGLLRVLTVPCQK 261
>gi|21361553 spleen tyrosine kinase isoform 1 [Homo sapiens]
Length = 635
Score = 44.7 bits (104), Expect = 1e-04
Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 9/117 (7%)
Query: 13 PRLDWFVHTQMGQLAQDGVPEWFHGAISREDAEN--LLESQPLGSFLIRVSHSHVGYTLS 70
P+L+ + T A + +P WFHG ISRE++E L+ S+ G FLIR ++ Y L
Sbjct: 152 PQLEKLIATT----AHEKMP-WFHGKISREESEQIVLIGSKTNGKFLIRARDNNGSYALC 206
Query: 71 YKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRRELLTQPCRQ 127
+ H+ + G IP K T L LV + K + +LT PC++
Sbjct: 207 LLHEGKVLHYRIDKDKTGKLSIPEGKKFDT-LWQLVEHYSYK-ADGLLRVLTVPCQK 261
>gi|219842230 feline sarcoma oncogene isoform 2 [Homo sapiens]
Length = 764
Score = 44.7 bits (104), Expect = 1e-04
Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 13/133 (9%)
Query: 8 PLPLPPRLDWFVHTQMGQLAQDGVPEWFHGAISREDAENLLESQPLGSFLIRVSHSHVGY 67
PL L P + +H Q+ W+HGAI R + LL G FL+R S Y
Sbjct: 386 PLQLIPEVQKPLHEQL----------WYHGAIPRAEVAELLVHS--GDFLVRESQGKQEY 433
Query: 68 TLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRRELLTQPCRQ 127
LS HF+++ LD+ + + GE L Q+P+ + ++
Sbjct: 434 VLSVLWDGLPRHFIIQSLDN-LYRLEGEGFPSIPLLIDHLLSTQQPLTKKSGVVLHRAVP 492
Query: 128 KDPANVDYEDLFL 140
KD +++EDL L
Sbjct: 493 KDKWVLNHEDLVL 505
>gi|4503687 feline sarcoma oncogene isoform 1 [Homo sapiens]
Length = 822
Score = 44.7 bits (104), Expect = 1e-04
Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 13/133 (9%)
Query: 8 PLPLPPRLDWFVHTQMGQLAQDGVPEWFHGAISREDAENLLESQPLGSFLIRVSHSHVGY 67
PL L P + +H Q+ W+HGAI R + LL G FL+R S Y
Sbjct: 444 PLQLIPEVQKPLHEQL----------WYHGAIPRAEVAELLVHS--GDFLVRESQGKQEY 491
Query: 68 TLSYKAQSSCCHFMVKLLDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRRELLTQPCRQ 127
LS HF+++ LD+ + + GE L Q+P+ + ++
Sbjct: 492 VLSVLWDGLPRHFIIQSLDN-LYRLEGEGFPSIPLLIDHLLSTQQPLTKKSGVVLHRAVP 550
Query: 128 KDPANVDYEDLFL 140
KD +++EDL L
Sbjct: 551 KDKWVLNHEDLVL 563
>gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]
Length = 526
Score = 44.7 bits (104), Expect = 1e-04
Identities = 36/106 (33%), Positives = 53/106 (50%), Gaps = 10/106 (9%)
Query: 33 EWFHGAISREDAEN--LLESQPLGSFLIRVSHSHVG-YTLSY-----KAQSSCCHFMVKL 84
EWF ISR+DAE L LGSF+IR S + G Y+LS + + H+ ++
Sbjct: 143 EWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRT 202
Query: 85 LDDGTFMIPGEKVAHTSLDALVTFHQQKPIEPRRELLTQPCRQKDP 130
LD+G F I + ++L LV H +K + + L+ PC P
Sbjct: 203 LDNGGFYI-SPRSTFSTLQELVD-HYKKGNDGLCQKLSVPCMSSKP 246
>gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]
Length = 1167
Score = 44.3 bits (103), Expect = 2e-04
Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Query: 34 WFHGAISREDAENLLESQPLGSFLIRVSHSHVG-YTLSYKAQSSCCHFMVKLLDDGTFMI 92
W+HG +SR AE LL S GSFL+R S S G ++S + + H+ + DG +
Sbjct: 158 WYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYV 217
Query: 93 PGEKVAHTSLDALVTFH 109
E ++L LV H
Sbjct: 218 TAES-RFSTLAELVHHH 233
>gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]
Length = 1182
Score = 44.3 bits (103), Expect = 2e-04
Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Query: 34 WFHGAISREDAENLLESQPLGSFLIRVSHSHVG-YTLSYKAQSSCCHFMVKLLDDGTFMI 92
W+HG +SR AE LL S GSFL+R S S G ++S + + H+ + DG +
Sbjct: 173 WYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYV 232
Query: 93 PGEKVAHTSLDALVTFH 109
E ++L LV H
Sbjct: 233 TAES-RFSTLAELVHHH 248
>gi|209862778 arg tyrosine kinase isoform e [Homo sapiens]
Length = 542
Score = 44.3 bits (103), Expect = 2e-04
Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Query: 34 WFHGAISREDAENLLESQPLGSFLIRVSHSHVG-YTLSYKAQSSCCHFMVKLLDDGTFMI 92
W+HG +SR AE LL S GSFL+R S S G ++S + + H+ + DG +
Sbjct: 152 WYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYV 211
Query: 93 PGEKVAHTSLDALVTFH 109
E ++L LV H
Sbjct: 212 TAES-RFSTLAELVHHH 227
>gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]
Length = 1064
Score = 44.3 bits (103), Expect = 2e-04
Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Query: 34 WFHGAISREDAENLLESQPLGSFLIRVSHSHVG-YTLSYKAQSSCCHFMVKLLDDGTFMI 92
W+HG +SR AE LL S GSFL+R S S G ++S + + H+ + DG +
Sbjct: 158 WYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYV 217
Query: 93 PGEKVAHTSLDALVTFH 109
E ++L LV H
Sbjct: 218 TAES-RFSTLAELVHHH 233
>gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]
Length = 1146
Score = 44.3 bits (103), Expect = 2e-04
Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
Query: 34 WFHGAISREDAENLLESQPLGSFLIRVSHSHVG-YTLSYKAQSSCCHFMVKLLDDGTFMI 92
W+HG +SR AE LL S GSFL+R S S G ++S + + H+ + DG +
Sbjct: 137 WYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYV 196
Query: 93 PGEKVAHTSLDALVTFH 109
E ++L LV H
Sbjct: 197 TAES-RFSTLAELVHHH 212
>gi|52630425 NCK adaptor protein 2 isoform A [Homo sapiens]
Length = 380
Score = 43.9 bits (102), Expect = 2e-04
Identities = 31/84 (36%), Positives = 50/84 (59%), Gaps = 5/84 (5%)
Query: 33 EWFHGAISREDAENLLESQPL-GSFLIRVSHSHVG-YTLSYKAQSSCCHFMVKLLDDGTF 90
EW++G ++R AE L + + G FLIR S S +++S KA HF V+L+D+ +
Sbjct: 284 EWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDN-VY 342
Query: 91 MIPGEKVAHTSLDALVTFHQQKPI 114
I G++ HT +D LV +++ PI
Sbjct: 343 CI-GQRRFHT-MDELVEHYKKAPI 364
>gi|52630423 NCK adaptor protein 2 isoform A [Homo sapiens]
Length = 380
Score = 43.9 bits (102), Expect = 2e-04
Identities = 31/84 (36%), Positives = 50/84 (59%), Gaps = 5/84 (5%)
Query: 33 EWFHGAISREDAENLLESQPL-GSFLIRVSHSHVG-YTLSYKAQSSCCHFMVKLLDDGTF 90
EW++G ++R AE L + + G FLIR S S +++S KA HF V+L+D+ +
Sbjct: 284 EWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDN-VY 342
Query: 91 MIPGEKVAHTSLDALVTFHQQKPI 114
I G++ HT +D LV +++ PI
Sbjct: 343 CI-GQRRFHT-MDELVEHYKKAPI 364
>gi|148596974 TXK tyrosine kinase [Homo sapiens]
Length = 527
Score = 43.9 bits (102), Expect = 2e-04
Identities = 26/85 (30%), Positives = 45/85 (52%), Gaps = 8/85 (9%)
Query: 33 EWFHGAISREDAENLLESQPL-GSFLIRVSHSHVGYTLSY------KAQSSCCHFMVKLL 85
EW+H I+R AE+LL + G+F++R S YT+S +++ H+ +K
Sbjct: 149 EWYHRNITRNQAEHLLRQESKEGAFIVRDSRHLGSYTISVFMGARRSTEAAIKHYQIKKN 208
Query: 86 DDGTFMIPGEKVAHTSLDALVTFHQ 110
D G + + E+ A S+ L+ +HQ
Sbjct: 209 DSGQWYV-AERHAFQSIPELIWYHQ 232
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,601,396
Number of Sequences: 37866
Number of extensions: 838557
Number of successful extensions: 2748
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 66
Number of HSP's successfully gapped in prelim test: 137
Number of HSP's that attempted gapping in prelim test: 2598
Number of HSP's gapped (non-prelim): 273
length of query: 352
length of database: 18,247,518
effective HSP length: 103
effective length of query: 249
effective length of database: 14,347,320
effective search space: 3572482680
effective search space used: 3572482680
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.