Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 14249170

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
sapiens]
         (410 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ...   831   0.0  
gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ...   716   0.0  
gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]    77   3e-14
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]     76   5e-14
gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]      75   8e-14
gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [...    57   2e-08
gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [...    57   2e-08
gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens]     56   7e-08
gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]    52   7e-07
gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens]     52   7e-07
gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ...    51   2e-06
gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ...    51   2e-06
gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [H...    51   2e-06
gi|190194416 F-box and leucine-rich repeat protein 15 [Homo sapi...    51   2e-06
gi|148922963 F-box and leucine-rich repeat protein 21 [Homo sapi...    49   8e-06
gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi...    48   2e-05
gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [H...    47   4e-05
gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens]     47   4e-05
gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens]     47   4e-05
gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]    46   5e-05
gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens]             44   3e-04
gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens]             44   3e-04
gi|30089922 F-box only protein 11 isoform 3 [Homo sapiens]             44   3e-04
gi|164663798 antagonist of mitotic exit network 1 homolog [Homo ...    43   6e-04
gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens]    41   0.002
gi|229576894 F-box and WD repeat domain containing 12 isoform 2 ...    39   0.007
gi|229576873 F-box and WD repeat domain containing 12 isoform 1 ...    39   0.007
gi|219281831 F-box protein 15 isoform 2 [Homo sapiens]                 37   0.032
gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [H...    37   0.032
gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [H...    37   0.032

>gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
           sapiens]
          Length = 410

 Score =  831 bits (2147), Expect = 0.0
 Identities = 410/410 (100%), Positives = 410/410 (100%)

Query: 1   MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG 60
           MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
Sbjct: 1   MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG 60

Query: 61  HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV 120
           HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
Sbjct: 61  HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV 120

Query: 121 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP 180
           SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
Sbjct: 121 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP 180

Query: 181 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC 240
           FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
Sbjct: 181 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC 240

Query: 241 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS 300
           SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
Sbjct: 241 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS 300

Query: 301 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLLVTRAG 360
           DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLLVTRAG
Sbjct: 301 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLLVTRAG 360

Query: 361 VRIRLDSDIGCPQTYRTSKLKSSHKLFCQHVRVICIFVCDFYFYRLVLKQ 410
           VRIRLDSDIGCPQTYRTSKLKSSHKLFCQHVRVICIFVCDFYFYRLVLKQ
Sbjct: 361 VRIRLDSDIGCPQTYRTSKLKSSHKLFCQHVRVICIFVCDFYFYRLVLKQ 410


>gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
           sapiens]
          Length = 424

 Score =  716 bits (1849), Expect = 0.0
 Identities = 354/354 (100%), Positives = 354/354 (100%)

Query: 1   MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG 60
           MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
Sbjct: 1   MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG 60

Query: 61  HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV 120
           HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
Sbjct: 61  HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV 120

Query: 121 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP 180
           SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
Sbjct: 121 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP 180

Query: 181 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC 240
           FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
Sbjct: 181 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC 240

Query: 241 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS 300
           SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
Sbjct: 241 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS 300

Query: 301 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLL 354
           DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLL
Sbjct: 301 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLL 354


>gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]
          Length = 436

 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 75/277 (27%), Positives = 122/277 (44%), Gaps = 22/277 (7%)

Query: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQG 159
           LP ELLL IFS L +  L + + V + W  LA D S WQ +DL   +   D+ GR++   
Sbjct: 28  LPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLF--DFQRDIEGRVVEN- 84

Query: 160 VIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEG-LRL 218
            I+ RC        L                  +  + L      C  ++ L+L G  + 
Sbjct: 85  -ISKRCGGFLRKLSLRGCLG-------------VGDNALRTFAQNCRNIEVLNLNGCTKT 130

Query: 219 SDPIVNTLAK-NSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVA 277
           +D    +L+K  S L  L+L+ C+  +  +L+ L   C  L++LN+SWC   T+  +Q A
Sbjct: 131 TDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQ-A 189

Query: 278 VAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQ-LNY 336
           +      +  L L G  + L+   L  +   CP LV L+L   + + ++      +  + 
Sbjct: 190 LVRGCGGLKALFLKGCTQ-LEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHK 248

Query: 337 LQHLSLSRCYDIIPETLLLVTRAGVRIRLDSDIGCPQ 373
           LQ L  S C +I    L  + +   R+R+     C Q
Sbjct: 249 LQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQ 285



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 38/139 (27%), Positives = 67/139 (48%), Gaps = 10/139 (7%)

Query: 193 IEVSTLHGILSQCSKLQNLSLEG-LRLSDPIVNTLAKNSN-LVRLNLSGCSGFSEFALQT 250
           +E   L  I + C +L  L+L+  L+++D  + T+ +  + L  L  SGCS  ++  L  
Sbjct: 208 LEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNA 267

Query: 251 LLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVR--- 307
           L  +C RL  L ++ C   T+    V    ++    +L      + +Q +D STL++   
Sbjct: 268 LGQNCPRLRILEVARCSQLTD----VGFTTLARNCHELEKMDLEECVQITD-STLIQLSI 322

Query: 308 RCPNLVHLDLSDSVMLKND 326
            CP L  L LS   ++ +D
Sbjct: 323 HCPRLQVLSLSHCELITDD 341



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 25/87 (28%), Positives = 44/87 (50%), Gaps = 2/87 (2%)

Query: 191 SVIEVSTLHGILSQCSKLQNLSLEGL-RLSDPIVNTLAKNSN-LVRLNLSGCSGFSEFAL 248
           S I  + L+ +   C +L+ L +    +L+D    TLA+N + L +++L  C   ++  L
Sbjct: 258 SNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTL 317

Query: 249 QTLLSSCSRLDELNLSWCFDFTEKHVQ 275
             L   C RL  L+LS C   T+  ++
Sbjct: 318 IQLSIHCPRLQVLSLSHCELITDDGIR 344


>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]
          Length = 423

 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 73/267 (27%), Positives = 123/267 (46%), Gaps = 24/267 (8%)

Query: 91  NFPGVSWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPD 150
           N  G+    LP ELLL IFS L +  L + + + K W  LA D S WQ +DL   N   D
Sbjct: 6   NDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLF--NFQID 63

Query: 151 VTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSV-IEVSTLHGILSQCSKLQ 209
           V GR++    I+ RC                 ++ + L   + +  S+L      C  ++
Sbjct: 64  VEGRVVEN--ISKRCGGF--------------LRKLSLRGCIGVGDSSLKTFAQNCRNIE 107

Query: 210 NLSLEG-LRLSDPIVNTLAK-NSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCF 267
           +L+L G  +++D    +L++  S L  L+L+ C   +  +L+ +   C  L+ LNLSWC 
Sbjct: 108 HLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCD 167

Query: 268 DFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDC 327
             T+  ++ A+      +  L L G  + L+   L  +   C  LV L+L     + ++ 
Sbjct: 168 QITKDGIE-ALVRGCRGLKALLLRGCTQ-LEDEALKHIQNYCHELVSLNLQSCSRITDEG 225

Query: 328 FQEFFQ-LNYLQHLSLSRCYDIIPETL 353
             +  +  + LQ L LS C ++   +L
Sbjct: 226 VVQICRGCHRLQALCLSGCSNLTDASL 252



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 45/166 (27%), Positives = 71/166 (42%), Gaps = 35/166 (21%)

Query: 193 IEVSTLHGILSQCSKLQNLSLEGL-RLSDPIVNTLAKNSN-LVRLNLSGCSGFSEFALQT 250
           +E   L  I + C +L +L+L+   R++D  V  + +  + L  L LSGCS  ++ +L  
Sbjct: 195 LEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTA 254

Query: 251 LLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDL-------- 302
           L  +C RL  L  + C   T+    +   +  E             L+K DL        
Sbjct: 255 LGLNCPRLQILEAARCSHLTDAGFTLLARNCHE-------------LEKMDLEECILITD 301

Query: 303 STLVR---RCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRC 345
           STL++    CP L  L LS   ++ +D          + HLS S C
Sbjct: 302 STLIQLSIHCPKLQALSLSHCELITDD---------GILHLSNSTC 338


>gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]
          Length = 491

 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 75/286 (26%), Positives = 127/286 (44%), Gaps = 48/286 (16%)

Query: 96  SWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRL 155
           S D LPD  ++ IFS L   +L + + VC+RWY LA D  LW+T+ LTG+ ++ D   ++
Sbjct: 113 SIDRLPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKV 172

Query: 156 LSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEG 215
           L++        R   D P                             + C  L+ +++ G
Sbjct: 173 LTR--------RLCQDTP-----------------------------NVCLMLETVTVSG 195

Query: 216 L-RLSDPIVNTLAK-NSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFT--- 270
             RL+D  + T+A+    L RL +SGC   S  A+  ++S C  L+ L++S C   T   
Sbjct: 196 CRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCIS 255

Query: 271 ---EKHVQVAVAHVSE-TITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKND 326
              E  ++++  H  + +I  L+++     L+   L T+   C  L HL L   V L ++
Sbjct: 256 LTREASIKLSPLHGKQISIRYLDMTDCFV-LEDEGLHTIAAHCTQLTHLYLRRCVRLTDE 314

Query: 327 CFQEF-FQLNYLQHLSLSRCYDIIPETLLLVTRAGVRIRLDSDIGC 371
             +        ++ LS+S C  +    L  + +   R+R  S   C
Sbjct: 315 GLRYLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHC 360



 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 69/251 (27%), Positives = 119/251 (47%), Gaps = 18/251 (7%)

Query: 113 CLPEL--LKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFM 170
           C PEL  L+VSG     Y + S+E+++  + L     H DV+G       I+     S  
Sbjct: 210 CCPELRRLEVSGC----YNI-SNEAVFDVVSLCPNLEHLDVSG-CSKVTCISLTREASIK 263

Query: 171 DQPLAEHFSPFRVQHMDLSNS-VIEVSTLHGILSQCSKLQNLSLEG-LRLSDPIVNTLAK 228
             PL  H     ++++D+++  V+E   LH I + C++L +L L   +RL+D  +  L  
Sbjct: 264 LSPL--HGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVI 321

Query: 229 N-SNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQ 287
             +++  L++S C   S+F L+ +    SRL  L+++ C   T+  ++    + S+ +  
Sbjct: 322 YCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSK-LRY 380

Query: 288 LNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLN--YLQHLSLSRC 345
           LN  G  + +    +  L + C  L  LD+     L +D   E   LN   L+ LSL  C
Sbjct: 381 LNARGC-EGITDHGVEYLAKNCTKLKSLDIG-KCPLVSDTGLECLALNCFNLKRLSLKSC 438

Query: 346 YDIIPETLLLV 356
             I  + L +V
Sbjct: 439 ESITGQGLQIV 449



 Score = 35.4 bits (80), Expect = 0.094
 Identities = 26/75 (34%), Positives = 38/75 (50%), Gaps = 5/75 (6%)

Query: 197 TLHGI---LSQCSKLQNLSLEGLRL-SDPIVNTLAKNS-NLVRLNLSGCSGFSEFALQTL 251
           T HG+      C+KL++L +    L SD  +  LA N  NL RL+L  C   +   LQ +
Sbjct: 390 TDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKSCESITGQGLQIV 449

Query: 252 LSSCSRLDELNLSWC 266
            ++C  L  LN+  C
Sbjct: 450 AANCFDLQTLNVQDC 464


>gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [Homo
            sapiens]
          Length = 1336

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 67/286 (23%), Positives = 122/286 (42%), Gaps = 55/286 (19%)

Query: 103  ELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTG-KNLHPDVTGRLLSQGVI 161
            E+ + +FS L   +L     VC+ W R   D+ LW  +DL   K++ P     L+  G+I
Sbjct: 1068 EVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITP-----LMLSGII 1122

Query: 162  AFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGIL--------------SQCSK 207
                      QP++   S   +    LS  +  +  L  ++              S C  
Sbjct: 1123 --------RRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPL 1174

Query: 208  LQNLS---LEGLR-------LSDPIVN------TLAKNSNLVRLNLSGCSGFSEFALQTL 251
            L+ L    +EGL+       LS P  N        +K  N+V L L+G    ++ +L+ +
Sbjct: 1175 LRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLD-ITDASLRLI 1233

Query: 252  LSSCSRLDELNLSWCFDFTEKHVQVAVA---HVSETITQLNLSGYRKNLQKSDLSTLVRR 308
            +     L +L+LS+C   T++ + +  A      +++T++NLS   K        +  +R
Sbjct: 1234 IRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNK--VTDQCLSFFKR 1291

Query: 309  CPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLL 354
            C N+ H+DL     +  +  ++F     +  +S+S  +  + E LL
Sbjct: 1292 CGNICHIDLRYCKQVTKEGCEQF-----IAEMSVSVQFGQVEEKLL 1332


>gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [Homo
            sapiens]
          Length = 1265

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 67/276 (24%), Positives = 117/276 (42%), Gaps = 51/276 (18%)

Query: 103  ELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTG-KNLHPDVTGRLLSQGVI 161
            E+ + +FS L   +L     VC+ W R   D+ LW  +DL   K++ P     L+  G+I
Sbjct: 999  EVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITP-----LMLSGII 1053

Query: 162  AFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGIL--------------SQCSK 207
                      QP++   S   +    LS  +  +  L  ++              S C  
Sbjct: 1054 --------RRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPL 1105

Query: 208  LQNLS---LEGLR-------LSDPIVN------TLAKNSNLVRLNLSGCSGFSEFALQTL 251
            L+ L    +EGL+       LS P  N        +K  N+V L L+G    ++ +L+ +
Sbjct: 1106 LRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLD-ITDASLRLI 1164

Query: 252  LSSCSRLDELNLSWCFDFTEKHVQVAVA---HVSETITQLNLSGYRKNLQKSDLSTLVRR 308
            +     L +L+LS+C   T++ + +  A      +++T++NLS   K        +  +R
Sbjct: 1165 IRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNK--VTDQCLSFFKR 1222

Query: 309  CPNLVHLDLS-DSVMLKNDCFQEFFQLNYLQHLSLS 343
            C N+ H+DL     + K  C Q   +++  Q  S S
Sbjct: 1223 CGNICHIDLRYCKQVTKEGCEQFIAEMSSFQGRSCS 1258


>gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens]
          Length = 621

 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 83/320 (25%), Positives = 133/320 (41%), Gaps = 73/320 (22%)

Query: 97  WDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLL 156
           +D LP EL+  I + L LP+L +++  CK                             LL
Sbjct: 280 FDKLPYELIQLILNHLTLPDLCRLAQTCK-----------------------------LL 310

Query: 157 SQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSN--SVIEVSTLHGILSQCSKLQ--NLS 212
           SQ                     P +  H++L    + ++ ++L  + S+C+ +Q  NLS
Sbjct: 311 SQHCC-----------------DPLQYIHLNLQPYWAKLDDTSLEFLQSRCTLVQWLNLS 353

Query: 213 LEGLR--LSDPIVNTLAK--NSNLVRLNLSGCSGF-SEFALQTLLSSCSRLDELNLSWCF 267
             G R  +S    +   K   S LVRL LS CS F +E  L+ +   C  L  LNLS C 
Sbjct: 354 WTGNRGFISVAGFSRFLKVCGSELVRLELS-CSHFLNETCLEVISEMCPNLQALNLSSC- 411

Query: 268 DFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKN-D 326
              +K    A  H+++  +   L  YR  ++++ L +++  C  L HL L   VM+++ D
Sbjct: 412 ---DKLPPQAFNHIAKLCSLKRLVLYRTKVEQTALLSILNFCSELQHLSLGSCVMIEDYD 468

Query: 327 CFQEFF--QLNYLQHLSLSRCYDIIPETLLLVTRAGVRIRLDSDIG-CPQ--------TY 375
                   +   L+ L L RC + I E  +    +G  +  + D+G CP         T 
Sbjct: 469 VIASMIGAKCKKLRTLDLWRCKN-ITENGIAELASGCPLLEELDLGWCPTLQSSTGCFTR 527

Query: 376 RTSKLKSSHKLFCQHVRVIC 395
              +L +  KLF    R +C
Sbjct: 528 LAHQLPNLQKLFLTANRSVC 547



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 47/172 (27%), Positives = 80/172 (46%), Gaps = 7/172 (4%)

Query: 183 VQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLS---DPIVNTL-AKNSNLVRLNLS 238
           ++ + L  + +E + L  IL+ CS+LQ+LSL    +    D I + + AK   L  L+L 
Sbjct: 428 LKRLVLYRTKVEQTALLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLW 487

Query: 239 GCSGFSEFALQTLLSSCSRLDELNLSWCFDF-TEKHVQVAVAHVSETITQLNLSGYRKNL 297
            C   +E  +  L S C  L+EL+L WC    +       +AH    + +L L+  R ++
Sbjct: 488 RCKNITENGIAELASGCPLLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTANR-SV 546

Query: 298 QKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQ-LNYLQHLSLSRCYDI 348
             +D+  L   C  L  LD+  + M+     ++  +    L  L +S C  I
Sbjct: 547 CDTDIDELACNCTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQI 598



 Score = 30.4 bits (67), Expect = 3.0
 Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 2/73 (2%)

Query: 204 QCSKLQNLSLEGLR-LSDPIVNTLAKN-SNLVRLNLSGCSGFSEFALQTLLSSCSRLDEL 261
           Q   LQ L L   R + D  ++ LA N + L +L++ G    S  +L+ LL SC  L  L
Sbjct: 531 QLPNLQKLFLTANRSVCDTDIDELACNCTRLQQLDILGTRMVSPASLRKLLESCKDLSLL 590

Query: 262 NLSWCFDFTEKHV 274
           ++S+C     + V
Sbjct: 591 DVSFCSQIDNRAV 603


>gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]
          Length = 1162

 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 64/291 (21%), Positives = 116/291 (39%), Gaps = 55/291 (18%)

Query: 96   SWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTG-KNLHPDVTGR 154
            SW  +  E+ + +F  L   EL +   VCK WY+   D+ LW  +DL+  K + P     
Sbjct: 891  SW--MQREVWMSVFRYLSRRELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSG 948

Query: 155  LLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGIL------------ 202
            ++ +             QP++   S   +    L+  V  +  L  +L            
Sbjct: 949  IIKR-------------QPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSAL 995

Query: 203  --SQCSKLQNLSLE-GLRLSDPIVNTL-------------AKNSNLVRLNLSGCSGFSEF 246
              S C  L+ L L   + + DP +  L             +K  N+    L+G    ++ 
Sbjct: 996  STSSCPLLRTLDLRWAVGIKDPQIRDLLTPPADKPGQDNRSKLRNMTDFRLAGLD-ITDA 1054

Query: 247  ALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSET---ITQLNLSGYRKNLQKSDLS 303
             L+ ++     L  L+LS C   T++   +  A  S T   +T+LN++G  K   ++ + 
Sbjct: 1055 TLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLI- 1113

Query: 304  TLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLL 354
              +RR  N+  +DL     +     + F     +  LS++  Y +  E L+
Sbjct: 1114 -YLRRIANVTLIDLRGCKQITRKACEHF-----ISDLSINSLYCLSDEKLI 1158


>gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens]
          Length = 326

 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 26/57 (45%), Positives = 35/57 (61%)

Query: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLL 156
           LPD +LL IFS L + + +++S VC RW RL  D  LW+ +DLT   + P V   LL
Sbjct: 7   LPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLYTMRPKVMWHLL 63


>gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2
           [Homo sapiens]
          Length = 690

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 95/400 (23%), Positives = 158/400 (39%), Gaps = 80/400 (20%)

Query: 77  KDFVIVRRPKLNRENFPGVSWDS--------------LPDELLLGIFSCLCLPELLKVSG 122
           K+ +I++R      NFP  S                 LP+  +L IF  L L +++    
Sbjct: 121 KNRLILKRAAAEESNFPERSSSEVFLVDETLKCDISLLPERAILQIFFYLSLKDVIICGQ 180

Query: 123 VCKRWYRLASDESLWQTLDLTG-KNLHPDV------------TGRLLSQGVI----AFR- 164
           V   W  +    SLW  +D +  KN+ PD               RL  +G +     FR 
Sbjct: 181 VNHAWMLMTQLNSLWNAIDFSSVKNVIPDKYIVSTLQRWRLNVLRLNFRGCLLRPKTFRS 240

Query: 165 --------------CPRSFMDQPLAEHFSPF--RVQHMDLSNSVIEVSTLHGILSQCSKL 208
                         CP +F D+ +  H S     V  ++LSN+ I   T+  +      L
Sbjct: 241 VSHCRNLQELNVSDCP-TFTDESM-RHISEGCPGVLCLNLSNTTITNRTMRLLPRHFHNL 298

Query: 209 QNLSLEGLR-LSDPIVNTLAKNSN---LVRLNLSGCSGFSEFALQTLLSSCSRLDELNLS 264
           QNLSL   R  +D  +  L   +    L+ L+LSGC+  S    + + +SC+ +  L ++
Sbjct: 299 QNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRYIANSCTGIMHLTIN 358

Query: 265 WCFDFTEKHVQVAV--------------AHVSE-TITQLNLSGYRK-----NLQKSDLS- 303
                T+  V+  V               H+S+ T   L+    RK     N + +D S 
Sbjct: 359 DMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTFRALSACKLRKIRFEGNKRVTDASF 418

Query: 304 -TLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETL--LLVTRAG 360
             + +  PNL H+ ++D   + +   +    L  L  L+L+ C  I    L   L   A 
Sbjct: 419 KFIDKNYPNLSHIYMADCKGITDSSLRSLSPLKQLTVLNLANCVRIGDMGLKQFLDGPAS 478

Query: 361 VRIRLDSDIGCPQTYRTSKLKSSHKLFCQHVRVICIFVCD 400
           +RIR  +   C +    S +K S +  C ++  + +  C+
Sbjct: 479 MRIRELNLSNCVRLSDASVMKLSER--CPNLNYLSLRNCE 516



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 35/131 (26%), Positives = 64/131 (48%), Gaps = 20/131 (15%)

Query: 164 RCPR-SFMDQPLAEHFSP---------FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSL 213
           RCP  +++     EH +          F +  +DLS + I    L+ +LS+  KL+ LS+
Sbjct: 503 RCPNLNYLSLRNCEHLTAQGIGYIVNIFSLVSIDLSGTDISNEGLN-VLSRHKKLKELSV 561

Query: 214 --------EGLRLSDPIVNTL-AKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLS 264
                   +G++++D  +  L AK   L  L++SGC   ++  L+ L   C +L  L + 
Sbjct: 562 SECYRITDDGIQITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLRILKMQ 621

Query: 265 WCFDFTEKHVQ 275
           +C + ++K  Q
Sbjct: 622 YCTNISKKAAQ 632



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 40/147 (27%), Positives = 63/147 (42%), Gaps = 24/147 (16%)

Query: 235 LNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYR 294
           LNLS C   S+ ++  L   C  L+ L+L  C   T + +   V   S  +  ++LSG  
Sbjct: 484 LNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNIFS--LVSIDLSG-- 539

Query: 295 KNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQ------EFF--QLNYLQHLSLSRCY 346
            ++    L+ L R    L  L +S+   + +D  Q      E    + +YL  L +S C 
Sbjct: 540 TDISNEGLNVLSRH-KKLKELSVSECYRITDDGIQITDSAMEMLSAKCHYLHILDISGC- 597

Query: 347 DIIPETLLLVTRAGVRIRLDSDIGCPQ 373
                  +L+T    +I  D  IGC Q
Sbjct: 598 -------VLLTD---QILEDLQIGCKQ 614


>gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1
           [Homo sapiens]
          Length = 735

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 95/400 (23%), Positives = 158/400 (39%), Gaps = 80/400 (20%)

Query: 77  KDFVIVRRPKLNRENFPGVSWDS--------------LPDELLLGIFSCLCLPELLKVSG 122
           K+ +I++R      NFP  S                 LP+  +L IF  L L +++    
Sbjct: 121 KNRLILKRAAAEESNFPERSSSEVFLVDETLKCDISLLPERAILQIFFYLSLKDVIICGQ 180

Query: 123 VCKRWYRLASDESLWQTLDLTG-KNLHPDV------------TGRLLSQGVI----AFR- 164
           V   W  +    SLW  +D +  KN+ PD               RL  +G +     FR 
Sbjct: 181 VNHAWMLMTQLNSLWNAIDFSSVKNVIPDKYIVSTLQRWRLNVLRLNFRGCLLRPKTFRS 240

Query: 165 --------------CPRSFMDQPLAEHFSPF--RVQHMDLSNSVIEVSTLHGILSQCSKL 208
                         CP +F D+ +  H S     V  ++LSN+ I   T+  +      L
Sbjct: 241 VSHCRNLQELNVSDCP-TFTDESM-RHISEGCPGVLCLNLSNTTITNRTMRLLPRHFHNL 298

Query: 209 QNLSLEGLR-LSDPIVNTLAKNSN---LVRLNLSGCSGFSEFALQTLLSSCSRLDELNLS 264
           QNLSL   R  +D  +  L   +    L+ L+LSGC+  S    + + +SC+ +  L ++
Sbjct: 299 QNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRYIANSCTGIMHLTIN 358

Query: 265 WCFDFTEKHVQVAV--------------AHVSE-TITQLNLSGYRK-----NLQKSDLS- 303
                T+  V+  V               H+S+ T   L+    RK     N + +D S 
Sbjct: 359 DMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTFRALSACKLRKIRFEGNKRVTDASF 418

Query: 304 -TLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETL--LLVTRAG 360
             + +  PNL H+ ++D   + +   +    L  L  L+L+ C  I    L   L   A 
Sbjct: 419 KFIDKNYPNLSHIYMADCKGITDSSLRSLSPLKQLTVLNLANCVRIGDMGLKQFLDGPAS 478

Query: 361 VRIRLDSDIGCPQTYRTSKLKSSHKLFCQHVRVICIFVCD 400
           +RIR  +   C +    S +K S +  C ++  + +  C+
Sbjct: 479 MRIRELNLSNCVRLSDASVMKLSER--CPNLNYLSLRNCE 516



 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 36/150 (24%), Positives = 74/150 (49%), Gaps = 3/150 (2%)

Query: 200 GILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLD 259
           G +     L ++ L G  +S+  +N L+++  L  L++S C   ++  +Q    S   L+
Sbjct: 524 GYIVNIFSLVSIDLSGTDISNEGLNVLSRHKKLKELSVSECYRITDDGIQAFCKSSLILE 583

Query: 260 ELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSD 319
            L++S+C   ++  ++ A+A     +T L+++G  K +  S +  L  +C  L  LD+S 
Sbjct: 584 HLDVSYCSQLSDMIIK-ALAIYCINLTSLSIAGCPK-ITDSAMEMLSAKCHYLHILDISG 641

Query: 320 SVMLKNDCFQEF-FQLNYLQHLSLSRCYDI 348
            V+L +   ++       L+ L +  C +I
Sbjct: 642 CVLLTDQILEDLQIGCKQLRILKMQYCTNI 671



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 8/166 (4%)

Query: 235 LNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYR 294
           LNLS C   S+ ++  L   C  L+ L+L  C   T + +   V   S  +  ++LSG  
Sbjct: 484 LNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNIFS--LVSIDLSG-- 539

Query: 295 KNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLN-YLQHLSLSRCYDIIPETL 353
            ++    L+ L R    L  L +S+   + +D  Q F + +  L+HL +S C  +    +
Sbjct: 540 TDISNEGLNVLSRH-KKLKELSVSECYRITDDGIQAFCKSSLILEHLDVSYCSQLSDMII 598

Query: 354 LLVTRAGVRIRLDSDIGCPQTYRTSKLKSSHKLFCQHVRVICIFVC 399
             +    + +   S  GCP+   ++    S K  C ++ ++ I  C
Sbjct: 599 KALAIYCINLTSLSIAGCPKITDSAMEMLSAK--CHYLHILDISGC 642



 Score = 36.2 bits (82), Expect = 0.055
 Identities = 26/96 (27%), Positives = 50/96 (52%), Gaps = 3/96 (3%)

Query: 183 VQHMDLSN-SVIEVSTLHGILSQCSKLQNLSLEGL-RLSDPIVNTL-AKNSNLVRLNLSG 239
           ++H+D+S  S +    +  +   C  L +LS+ G  +++D  +  L AK   L  L++SG
Sbjct: 582 LEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISG 641

Query: 240 CSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQ 275
           C   ++  L+ L   C +L  L + +C + ++K  Q
Sbjct: 642 CVLLTDQILEDLQIGCKQLRILKMQYCTNISKKAAQ 677


>gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [Homo
           sapiens]
          Length = 539

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 48/185 (25%), Positives = 77/185 (41%), Gaps = 36/185 (19%)

Query: 85  PKLNRENFPGVSW-DSLPDELLLGIFSCLC-----LPELLKVSGVCKRWYRLASDESLWQ 138
           P    E  P   W D +P E+L+ IF  L      +P L + + VC+RW   AS  +LW 
Sbjct: 99  PTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWH 158

Query: 139 TLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTL 198
           T+ L+       + GR    GV A +   + ++  +   FS  ++Q + L +   +V  +
Sbjct: 159 TVTLSS-----PLVGRPAKGGVKAEKKLLASLEWLMPNRFS--QLQRLTLIHWKSQVHPV 211

Query: 199 HGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRL 258
             ++ +C                          L  L LSGC G +  AL  L  +C +L
Sbjct: 212 LKLVGECC-----------------------PRLTFLKLSGCHGVTADALVMLAKACCQL 248

Query: 259 DELNL 263
             L+L
Sbjct: 249 HSLDL 253


>gi|190194416 F-box and leucine-rich repeat protein 15 [Homo
           sapiens]
          Length = 300

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 50/201 (24%), Positives = 84/201 (41%), Gaps = 31/201 (15%)

Query: 196 STLHGILSQCSKLQNLSLEGLR--LSDP-IVNTLAKNSNLVRLNLSGCSGFSEFALQTLL 252
           + L  +L     LQ L+L      LSD  +V  LA+N  L  + L GC   S  AL  L 
Sbjct: 77  AALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALA 136

Query: 253 SSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRK----------------- 295
             C RL  L+L+ C D+ +      +A     + +L+L+  R+                 
Sbjct: 137 EGCPRLQRLSLAHC-DWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGL 195

Query: 296 ---------NLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQ-LNYLQHLSLSRC 345
                    N+  + +  L R CP L HLDL+  + + +D  +   +    L+ L +  C
Sbjct: 196 RSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHC 255

Query: 346 YDIIPETLLLVTRAGVRIRLD 366
           + +   +L  + + GV I ++
Sbjct: 256 HHVAESSLSRLRKRGVDIDVE 276


>gi|148922963 F-box and leucine-rich repeat protein 21 [Homo
           sapiens]
          Length = 434

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 49/201 (24%), Positives = 82/201 (40%), Gaps = 31/201 (15%)

Query: 95  VSWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLW--------QTLDLTGKN 146
           + W SLP  ++L IF  L L +    S VC+RW  +     LW        Q+   + K+
Sbjct: 40  LDWGSLPHHVVLQIFQYLPLLDRACASSVCRRWNEVFHISDLWRKFEFELNQSATSSFKS 99

Query: 147 LHPDVTGRLLSQ-----GVIAFRCPRSFMDQPLA---------------EHFSPFRVQHM 186
            HPD+  +++ +       ++F+   S      A                  S  +   M
Sbjct: 100 THPDLIQQIIKKHFAHLQYVSFKVDSSAESAEAACDILSQLVNCSIQTLGLISTAKPSFM 159

Query: 187 DLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTL-AKNSNLVRL-NLSGCSGFS 244
           ++S S   VS L  +      L ++ +E   + DP +  L A NS+ +RL  +S C   S
Sbjct: 160 NVSESHF-VSALTVVFINSKSLSSIKIEDTPVDDPSLKILVANNSDTLRLPKMSSCPHVS 218

Query: 245 EFALQTLLSSCSRLDELNLSW 265
              +  +   C  L EL L++
Sbjct: 219 SDGILCVADRCQGLRELALNY 239


>gi|157168349 F-box and leucine-rich repeat protein 19 [Homo
           sapiens]
          Length = 694

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 95/378 (25%), Positives = 137/378 (36%), Gaps = 101/378 (26%)

Query: 6   LQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEP-DSENIPQELLSNLGHPES 64
           L+ +PD SS+ + S     DS   S      G S  E E P ++ N  +    + G  E+
Sbjct: 317 LERVPDTSSSSSDS-----DSDSDSS-----GTSLSEDEAPGEARNGRRPARGSSGEKEN 366

Query: 65  PPRKRLKSKGSDKDFV------------------IVRRPKLNREN----FPGVSWDSLPD 102
              +R    GS    +                  +VR P  + E         S   LP 
Sbjct: 367 RGGRRAVRPGSGGPLLSWPLGPAPPPRPPQLERHVVRPPPRSPEPDTLPLAAGSDHPLPR 426

Query: 103 ELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIA 162
              L +F  L   EL     VC+ W R   D+ LW  +DL+ +     +T  +LS GV+ 
Sbjct: 427 AAWLRVFQHLGPRELCICMRVCRTWSRWCYDKRLWPRMDLSRRK---SLTPPMLS-GVVR 482

Query: 163 FRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEG------- 215
            R PR+                 +DLS + +    L  +L++   LQ L L G       
Sbjct: 483 -RQPRA-----------------LDLSWTGVSKKQLMWLLNRLQGLQELVLSGCSWLSVS 524

Query: 216 ---------LRLSDPIVNTLAKNSNL------------------------VRLNLSGCSG 242
                    LRL D       K+S L                          L L+G   
Sbjct: 525 ALGSAPLPALRLLDLRWIEDVKDSQLRELLLPPPDTKPGQTESRGRLQGVAELRLAGLE- 583

Query: 243 FSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVS---ETITQLNLSGYRKNLQK 299
            ++ +L+ LL    +L  L+LS C    +  V +  A  S   ET+  LNL+G  +    
Sbjct: 584 LTDASLRLLLRHAPQLSALDLSHCAHVGDPSVHLLTAPTSPLRETLVHLNLAGCHR--LT 641

Query: 300 SDLSTLVRRCPNLVHLDL 317
                L RRCP L  LDL
Sbjct: 642 DHCLPLFRRCPRLRRLDL 659


>gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [Homo
           sapiens]
          Length = 533

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 49/185 (26%), Positives = 73/185 (39%), Gaps = 42/185 (22%)

Query: 85  PKLNRENFPGVSW-DSLPDELLLGIFSCLC-----LPELLKVSGVCKRWYRLASDESLWQ 138
           P    E  P   W D +P E+L+ IF  L      +P L + + VC+RW   AS  +LW 
Sbjct: 99  PTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWH 158

Query: 139 TLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTL 198
           T+ L+       + GR    GV A +   + ++  +   F                    
Sbjct: 159 TVTLSS-----PLVGRPAKGGVKAEKKLLASLEWLMPNRF-------------------- 193

Query: 199 HGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRL 258
                  S+LQ L+L  +     +V        L  L LSGC G +  AL  L  +C +L
Sbjct: 194 -------SQLQRLTL--IHWKSQLVGECC--PRLTFLKLSGCHGVTADALVMLAKACCQL 242

Query: 259 DELNL 263
             L+L
Sbjct: 243 HSLDL 247


>gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens]
          Length = 223

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 51/177 (28%), Positives = 79/177 (44%), Gaps = 17/177 (9%)

Query: 198 LHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTL-LSSCS 256
           +HG  SQ + L       L+ S P +   A  +        G S  +  ALQ L L++CS
Sbjct: 28  MHGAPSQLASLSLAHCSSLK-SRPELEHQASGTKDACPEPQGPSLLTLRALQELDLTACS 86

Query: 257 RLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLD 316
           +L + +L+    F +             + QL+LS     L  + L  + R CP+L HL 
Sbjct: 87  KLTDASLAKVLQFLQ-------------LRQLSLS-LLPELTDNGLVAVARGCPSLEHLA 132

Query: 317 LSDSVMLKNDCF-QEFFQLNYLQHLSLSRCYDIIPETLLLVTRAGVRIRLDSDIGCP 372
           LS    L +  + Q       LQHL+LS C  +I +TL  + +A  ++R+     CP
Sbjct: 133 LSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCP 189


>gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens]
          Length = 223

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 51/177 (28%), Positives = 79/177 (44%), Gaps = 17/177 (9%)

Query: 198 LHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTL-LSSCS 256
           +HG  SQ + L       L+ S P +   A  +        G S  +  ALQ L L++CS
Sbjct: 28  MHGAPSQLASLSLAHCSSLK-SRPELEHQASGTKDACPEPQGPSLLTLRALQELDLTACS 86

Query: 257 RLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLD 316
           +L + +L+    F +             + QL+LS     L  + L  + R CP+L HL 
Sbjct: 87  KLTDASLAKVLQFLQ-------------LRQLSLS-LLPELTDNGLVAVARGCPSLEHLA 132

Query: 317 LSDSVMLKNDCF-QEFFQLNYLQHLSLSRCYDIIPETLLLVTRAGVRIRLDSDIGCP 372
           LS    L +  + Q       LQHL+LS C  +I +TL  + +A  ++R+     CP
Sbjct: 133 LSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCP 189


>gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]
          Length = 479

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 63/275 (22%), Positives = 114/275 (41%), Gaps = 18/275 (6%)

Query: 102 DELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVI 161
           +++L G+F      E   ++ VCK W R+      W  L      LH      +L  G  
Sbjct: 99  EKILNGLFWYFSACEKCVLAQVCKAWRRVLYQPKFWAGLTPV---LHAKELYNVLPGGEK 155

Query: 162 AFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVS-TLHGILSQCSKLQNLSLEGLRLSD 220
            F   + F  +   E F    V  +D+   +   + +  G+ +   K   ++  GL +  
Sbjct: 156 EFVNLQGFAARGF-EGFCLVGVSDLDICEFIDNYALSKKGVKAMSLKRSTITDAGLEVM- 213

Query: 221 PIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAH 280
                L +   +VRL LSGC+ F+E  L + LS  +R+  L++S C +  +  +  A++ 
Sbjct: 214 -----LEQMQGVVRLELSGCNDFTEAGLWSSLS--ARITSLSVSDCINVADDAI-AAISQ 265

Query: 281 VSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHL--DLSDSVMLKNDCFQEFFQLNYLQ 338
           +   + +L+L  Y  ++  + L+    R  +  H    LS   +  +        L  L 
Sbjct: 266 LLPNLAELSLQAY--HVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLT 323

Query: 339 HLSLSRCYDIIPETLLLVTRAGVRIRLDSDIGCPQ 373
            LSLS C  +  + + LV     ++R      CP+
Sbjct: 324 ALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPR 358



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 44/161 (27%), Positives = 72/161 (44%), Gaps = 11/161 (6%)

Query: 197 TLHGILSQCSKLQNL---SLEGL-RLSDPIVNTLAKNSNLVR-LNLSGCSGFSEFALQTL 251
           T HG+++    L NL   SL G  +++D  V  +A+N   +R L+LS C   ++ AL+ +
Sbjct: 308 TNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYV 367

Query: 252 LSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTL-VRRCP 310
                RL+EL L  C   T+      ++++S T++ L     R   Q  D     +    
Sbjct: 368 ACDLHRLEELVLDRCVRITD----TGLSYLS-TMSSLRSLYLRWCCQVQDFGLKHLLALG 422

Query: 311 NLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPE 351
           +L  L  +   +L         QL  L+ L L+ C    PE
Sbjct: 423 SLRLLSPAGCPLLTTTGLSGLVQLQELEELELTNCPGATPE 463


>gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens]
          Length = 843

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 5/58 (8%)

Query: 98  DSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTL-----DLTGKNLHPD 150
           + LPDE++L IFS L   +L + + VCKR+  LA+D  LW+ L     + T   +HP+
Sbjct: 73  EKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPE 130


>gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens]
          Length = 686

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 5/58 (8%)

Query: 98  DSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTL-----DLTGKNLHPD 150
           + LPDE++L IFS L   +L + + VCKR+  LA+D  LW+ L     + T   +HP+
Sbjct: 73  EKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPE 130


>gi|30089922 F-box only protein 11 isoform 3 [Homo sapiens]
          Length = 585

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 5/58 (8%)

Query: 98  DSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTL-----DLTGKNLHPD 150
           + LPDE++L IFS L   +L + + VCKR+  LA+D  LW+ L     + T   +HP+
Sbjct: 73  EKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPE 130


>gi|164663798 antagonist of mitotic exit network 1 homolog [Homo
           sapiens]
          Length = 258

 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 46/205 (22%), Positives = 94/205 (45%), Gaps = 27/205 (13%)

Query: 187 DLSNSVIEVSTLHGILSQCS-------KLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSG 239
           ++ + +I++ ++ G ++  +       ++Q L L    +SD  +  L+    L +LNL+ 
Sbjct: 35  NIKDRLIKIMSMQGQITDSNISEILHPEVQTLDLRSCDISDAALLHLSNCRKLKKLNLNA 94

Query: 240 CSG----FSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRK 295
             G     +   ++ + SSCS L E +L  C + T++ V VA+A   + +  ++L G   
Sbjct: 95  SKGNRVSVTSEGIKAVASSCSYLHEASLKRCCNLTDEGV-VALALNCQLLKIIDLGGC-L 152

Query: 296 NLQKSDLSTLVRRCPNLVHLD-----LSDS---VMLKNDCFQEFFQLNYLQHLSLSRCYD 347
           ++    L  L + CP L  +D     +SDS    ++   C ++      L+ + +  C +
Sbjct: 153 SITDVSLHALGKNCPFLQCVDFSATQVSDSGVIALVSGPCAKK------LEEIHMGHCVN 206

Query: 348 IIPETLLLVTRAGVRIRLDSDIGCP 372
           +    +  V     +IR+    GCP
Sbjct: 207 LTDGAVEAVLTYCPQIRILLFHGCP 231


>gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens]
          Length = 418

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 60/282 (21%), Positives = 119/282 (42%), Gaps = 32/282 (11%)

Query: 103 ELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLD--LTGKNLHPDVTGRLLSQG- 159
           ELL  IF  L + +  + + VC  W   A  +S+W+ ++  L  +  +P +   L ++G 
Sbjct: 11  ELLAMIFGYLDVRDKGRAAQVCTAWRDAAYHKSVWRGVEAKLHLRRANPSLFPSLQARGI 70

Query: 160 ----VIAFRCPRSFMDQPLAEHFSPFRVQHMDLSN--SVIEVSTLHGILSQCSKLQNLSL 213
               +++ R   S++ Q +A       ++ ++LS   ++ +    H  + +   L+ L+L
Sbjct: 71  RRVQILSLRRSLSYVIQGMA------NIESLNLSGCYNLTDNGLGHAFVQEIGSLRALNL 124

Query: 214 EGLR-LSDPIVNTLAKN-SNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTE 271
              + ++D  +  +A+    L  L L GCS  +   L  +     RL  LNL  C   ++
Sbjct: 125 SLCKQITDSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSCRHLSD 184

Query: 272 KHVQVAVAHVSET----------ITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSV 321
               V + H++            + QL L   +K L    L  + R    L  L+LS   
Sbjct: 185 ----VGIGHLAGMTRSAAEGCLGLEQLTLQDCQK-LTDLSLKHISRGLTGLRLLNLSFCG 239

Query: 322 MLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLLVTRAGVRI 363
            + +        +  L+ L+L  C +I    ++ +    +R+
Sbjct: 240 GISDAGLLHLSHMGSLRSLNLRSCDNISDTGIMHLAMGSLRL 281



 Score = 36.6 bits (83), Expect = 0.042
 Identities = 43/175 (24%), Positives = 78/175 (44%), Gaps = 22/175 (12%)

Query: 202 LSQCSKLQNLSLE-------GLRL---------SDPIVNTLAKNSNLVRLNLSGCSGFSE 245
           L  C KL +LSL+       GLRL         SD  +  L+   +L  LNL  C   S+
Sbjct: 209 LQDCQKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGLLHLSHMGSLRSLNLRSCDNISD 268

Query: 246 FALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQL-NLSGYRKNLQKSDLST 304
             +  L     RL  L++S+C    +K    ++A++++ +  L +LS    ++    ++ 
Sbjct: 269 TGIMHLAMGSLRLSGLDVSFC----DKVGDQSLAYIAQGLDGLKSLSLCSCHISDDGINR 324

Query: 305 LVRRCPNLVHLDLSDSVMLKNDCFQEFFQ-LNYLQHLSLSRCYDIIPETLLLVTR 358
           +VR+   L  L++   V + +   +   + L+ L  + L  C  I    L  +T+
Sbjct: 325 MVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQLTGIDLYGCTRITKRGLERITQ 379


>gi|229576894 F-box and WD repeat domain containing 12 isoform 2
           [Homo sapiens]
          Length = 394

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 22/43 (51%), Positives = 27/43 (62%)

Query: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDL 142
           LPD  L  IFS L L  LL+VS V K W R+A  + LW++L L
Sbjct: 5   LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47


>gi|229576873 F-box and WD repeat domain containing 12 isoform 1
           [Homo sapiens]
          Length = 464

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 22/43 (51%), Positives = 27/43 (62%)

Query: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDL 142
           LPD  L  IFS L L  LL+VS V K W R+A  + LW++L L
Sbjct: 5   LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47


>gi|219281831 F-box protein 15 isoform 2 [Homo sapiens]
          Length = 510

 Score = 37.0 bits (84), Expect = 0.032
 Identities = 18/40 (45%), Positives = 24/40 (60%)

Query: 98  DSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLW 137
           D +P E+LL IFS L    LL    V +R+Y LA+D  +W
Sbjct: 75  DGMPSEILLKIFSYLDAVSLLCTGCVSRRFYHLANDNFIW 114


>gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [Homo
           sapiens]
          Length = 565

 Score = 37.0 bits (84), Expect = 0.032
 Identities = 56/232 (24%), Positives = 87/232 (37%), Gaps = 37/232 (15%)

Query: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTL-------------DLTGKN 146
           LP E++L IFS L   EL + S V  +W +L    SLW+ L               T  +
Sbjct: 82  LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHWARGDWYSGPATELD 141

Query: 147 LHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCS 206
             PD     +       R    + +    +       + + +S + +E   LHG++    
Sbjct: 142 TEPD--DEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHGLIHNVL 199

Query: 207 KLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGF------------SEFALQTLLSS 254
                S++ L L+     + A +S +VR  L  C               S F   + L  
Sbjct: 200 PYVGTSVKTLVLA----YSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWLGC 255

Query: 255 CSRLDELNLSWCFDFTEKHVQVAVAHVSETITQL--NLSGYRKNLQKSDLST 304
           C  L  L+LS C    EK   VA+  +S  +  L  + SG+ K       ST
Sbjct: 256 CQSLRHLDLSGC----EKITDVALEKISRALGILTSHQSGFLKTSTSKITST 303



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 5/83 (6%)

Query: 280 HVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQL---NY 336
           +V  ++  L L+ Y   +    +  ++  CPNL HLDL+ +  + +  F  +  L     
Sbjct: 201 YVGTSVKTLVLA-YSSAVSSKMVRQILELCPNLEHLDLTQT-DISDSAFDSWSWLGCCQS 258

Query: 337 LQHLSLSRCYDIIPETLLLVTRA 359
           L+HL LS C  I    L  ++RA
Sbjct: 259 LRHLDLSGCEKITDVALEKISRA 281



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 16/46 (34%), Positives = 23/46 (50%)

Query: 232 LVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVA 277
           L  LNLSGC   +   LQ L+S+C  L++    +C +    H   A
Sbjct: 502 LEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADTA 547


>gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [Homo
           sapiens]
          Length = 691

 Score = 37.0 bits (84), Expect = 0.032
 Identities = 56/232 (24%), Positives = 87/232 (37%), Gaps = 37/232 (15%)

Query: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTL-------------DLTGKN 146
           LP E++L IFS L   EL + S V  +W +L    SLW+ L               T  +
Sbjct: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHWARGDWYSGPATELD 267

Query: 147 LHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCS 206
             PD     +       R    + +    +       + + +S + +E   LHG++    
Sbjct: 268 TEPD--DEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHGLIHNVL 325

Query: 207 KLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGF------------SEFALQTLLSS 254
                S++ L L+     + A +S +VR  L  C               S F   + L  
Sbjct: 326 PYVGTSVKTLVLA----YSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWLGC 381

Query: 255 CSRLDELNLSWCFDFTEKHVQVAVAHVSETITQL--NLSGYRKNLQKSDLST 304
           C  L  L+LS C    EK   VA+  +S  +  L  + SG+ K       ST
Sbjct: 382 CQSLRHLDLSGC----EKITDVALEKISRALGILTSHQSGFLKTSTSKITST 429



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 5/83 (6%)

Query: 280 HVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQL---NY 336
           +V  ++  L L+ Y   +    +  ++  CPNL HLDL+ +  + +  F  +  L     
Sbjct: 327 YVGTSVKTLVLA-YSSAVSSKMVRQILELCPNLEHLDLTQT-DISDSAFDSWSWLGCCQS 384

Query: 337 LQHLSLSRCYDIIPETLLLVTRA 359
           L+HL LS C  I    L  ++RA
Sbjct: 385 LRHLDLSGCEKITDVALEKISRA 407



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 16/46 (34%), Positives = 23/46 (50%)

Query: 232 LVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVA 277
           L  LNLSGC   +   LQ L+S+C  L++    +C +    H   A
Sbjct: 628 LEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADTA 673


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,587,865
Number of Sequences: 37866
Number of extensions: 682458
Number of successful extensions: 2058
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 41
Number of HSP's that attempted gapping in prelim test: 1882
Number of HSP's gapped (non-prelim): 154
length of query: 410
length of database: 18,247,518
effective HSP length: 105
effective length of query: 305
effective length of database: 14,271,588
effective search space: 4352834340
effective search space used: 4352834340
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press