BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo sapiens] (410 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ... 831 0.0 gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ... 716 0.0 gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens] 77 3e-14 gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens] 76 5e-14 gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens] 75 8e-14 gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [... 57 2e-08 gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [... 57 2e-08 gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens] 56 7e-08 gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens] 52 7e-07 gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens] 52 7e-07 gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ... 51 2e-06 gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ... 51 2e-06 gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [H... 51 2e-06 gi|190194416 F-box and leucine-rich repeat protein 15 [Homo sapi... 51 2e-06 gi|148922963 F-box and leucine-rich repeat protein 21 [Homo sapi... 49 8e-06 gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi... 48 2e-05 gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [H... 47 4e-05 gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens] 47 4e-05 gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens] 47 4e-05 gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens] 46 5e-05 gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens] 44 3e-04 gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens] 44 3e-04 gi|30089922 F-box only protein 11 isoform 3 [Homo sapiens] 44 3e-04 gi|164663798 antagonist of mitotic exit network 1 homolog [Homo ... 43 6e-04 gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens] 41 0.002 gi|229576894 F-box and WD repeat domain containing 12 isoform 2 ... 39 0.007 gi|229576873 F-box and WD repeat domain containing 12 isoform 1 ... 39 0.007 gi|219281831 F-box protein 15 isoform 2 [Homo sapiens] 37 0.032 gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [H... 37 0.032 gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [H... 37 0.032 >gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo sapiens] Length = 410 Score = 831 bits (2147), Expect = 0.0 Identities = 410/410 (100%), Positives = 410/410 (100%) Query: 1 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG 60 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG Sbjct: 1 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG 60 Query: 61 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV 120 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV Sbjct: 61 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV 120 Query: 121 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP 180 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP Sbjct: 121 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP 180 Query: 181 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC 240 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC Sbjct: 181 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC 240 Query: 241 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS 300 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS Sbjct: 241 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS 300 Query: 301 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLLVTRAG 360 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLLVTRAG Sbjct: 301 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLLVTRAG 360 Query: 361 VRIRLDSDIGCPQTYRTSKLKSSHKLFCQHVRVICIFVCDFYFYRLVLKQ 410 VRIRLDSDIGCPQTYRTSKLKSSHKLFCQHVRVICIFVCDFYFYRLVLKQ Sbjct: 361 VRIRLDSDIGCPQTYRTSKLKSSHKLFCQHVRVICIFVCDFYFYRLVLKQ 410 >gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo sapiens] Length = 424 Score = 716 bits (1849), Expect = 0.0 Identities = 354/354 (100%), Positives = 354/354 (100%) Query: 1 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG 60 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG Sbjct: 1 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG 60 Query: 61 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV 120 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV Sbjct: 61 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV 120 Query: 121 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP 180 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP Sbjct: 121 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP 180 Query: 181 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC 240 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC Sbjct: 181 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC 240 Query: 241 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS 300 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS Sbjct: 241 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS 300 Query: 301 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLL 354 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLL Sbjct: 301 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLL 354 >gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens] Length = 436 Score = 77.0 bits (188), Expect = 3e-14 Identities = 75/277 (27%), Positives = 122/277 (44%), Gaps = 22/277 (7%) Query: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQG 159 LP ELLL IFS L + L + + V + W LA D S WQ +DL + D+ GR++ Sbjct: 28 LPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLF--DFQRDIEGRVVEN- 84 Query: 160 VIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEG-LRL 218 I+ RC L + + L C ++ L+L G + Sbjct: 85 -ISKRCGGFLRKLSLRGCLG-------------VGDNALRTFAQNCRNIEVLNLNGCTKT 130 Query: 219 SDPIVNTLAK-NSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVA 277 +D +L+K S L L+L+ C+ + +L+ L C L++LN+SWC T+ +Q A Sbjct: 131 TDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQ-A 189 Query: 278 VAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQ-LNY 336 + + L L G + L+ L + CP LV L+L + + ++ + + Sbjct: 190 LVRGCGGLKALFLKGCTQ-LEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHK 248 Query: 337 LQHLSLSRCYDIIPETLLLVTRAGVRIRLDSDIGCPQ 373 LQ L S C +I L + + R+R+ C Q Sbjct: 249 LQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQ 285 Score = 40.4 bits (93), Expect = 0.003 Identities = 38/139 (27%), Positives = 67/139 (48%), Gaps = 10/139 (7%) Query: 193 IEVSTLHGILSQCSKLQNLSLEG-LRLSDPIVNTLAKNSN-LVRLNLSGCSGFSEFALQT 250 +E L I + C +L L+L+ L+++D + T+ + + L L SGCS ++ L Sbjct: 208 LEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNA 267 Query: 251 LLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVR--- 307 L +C RL L ++ C T+ V ++ +L + +Q +D STL++ Sbjct: 268 LGQNCPRLRILEVARCSQLTD----VGFTTLARNCHELEKMDLEECVQITD-STLIQLSI 322 Query: 308 RCPNLVHLDLSDSVMLKND 326 CP L L LS ++ +D Sbjct: 323 HCPRLQVLSLSHCELITDD 341 Score = 31.2 bits (69), Expect = 1.8 Identities = 25/87 (28%), Positives = 44/87 (50%), Gaps = 2/87 (2%) Query: 191 SVIEVSTLHGILSQCSKLQNLSLEGL-RLSDPIVNTLAKNSN-LVRLNLSGCSGFSEFAL 248 S I + L+ + C +L+ L + +L+D TLA+N + L +++L C ++ L Sbjct: 258 SNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTL 317 Query: 249 QTLLSSCSRLDELNLSWCFDFTEKHVQ 275 L C RL L+LS C T+ ++ Sbjct: 318 IQLSIHCPRLQVLSLSHCELITDDGIR 344 >gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens] Length = 423 Score = 76.3 bits (186), Expect = 5e-14 Identities = 73/267 (27%), Positives = 123/267 (46%), Gaps = 24/267 (8%) Query: 91 NFPGVSWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPD 150 N G+ LP ELLL IFS L + L + + + K W LA D S WQ +DL N D Sbjct: 6 NDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLF--NFQID 63 Query: 151 VTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSV-IEVSTLHGILSQCSKLQ 209 V GR++ I+ RC ++ + L + + S+L C ++ Sbjct: 64 VEGRVVEN--ISKRCGGF--------------LRKLSLRGCIGVGDSSLKTFAQNCRNIE 107 Query: 210 NLSLEG-LRLSDPIVNTLAK-NSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCF 267 +L+L G +++D +L++ S L L+L+ C + +L+ + C L+ LNLSWC Sbjct: 108 HLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCD 167 Query: 268 DFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDC 327 T+ ++ A+ + L L G + L+ L + C LV L+L + ++ Sbjct: 168 QITKDGIE-ALVRGCRGLKALLLRGCTQ-LEDEALKHIQNYCHELVSLNLQSCSRITDEG 225 Query: 328 FQEFFQ-LNYLQHLSLSRCYDIIPETL 353 + + + LQ L LS C ++ +L Sbjct: 226 VVQICRGCHRLQALCLSGCSNLTDASL 252 Score = 40.4 bits (93), Expect = 0.003 Identities = 45/166 (27%), Positives = 71/166 (42%), Gaps = 35/166 (21%) Query: 193 IEVSTLHGILSQCSKLQNLSLEGL-RLSDPIVNTLAKNSN-LVRLNLSGCSGFSEFALQT 250 +E L I + C +L +L+L+ R++D V + + + L L LSGCS ++ +L Sbjct: 195 LEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTA 254 Query: 251 LLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDL-------- 302 L +C RL L + C T+ + + E L+K DL Sbjct: 255 LGLNCPRLQILEAARCSHLTDAGFTLLARNCHE-------------LEKMDLEECILITD 301 Query: 303 STLVR---RCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRC 345 STL++ CP L L LS ++ +D + HLS S C Sbjct: 302 STLIQLSIHCPKLQALSLSHCELITDD---------GILHLSNSTC 338 >gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens] Length = 491 Score = 75.5 bits (184), Expect = 8e-14 Identities = 75/286 (26%), Positives = 127/286 (44%), Gaps = 48/286 (16%) Query: 96 SWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRL 155 S D LPD ++ IFS L +L + + VC+RWY LA D LW+T+ LTG+ ++ D ++ Sbjct: 113 SIDRLPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVDRALKV 172 Query: 156 LSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEG 215 L++ R D P + C L+ +++ G Sbjct: 173 LTR--------RLCQDTP-----------------------------NVCLMLETVTVSG 195 Query: 216 L-RLSDPIVNTLAK-NSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFT--- 270 RL+D + T+A+ L RL +SGC S A+ ++S C L+ L++S C T Sbjct: 196 CRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCIS 255 Query: 271 ---EKHVQVAVAHVSE-TITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKND 326 E ++++ H + +I L+++ L+ L T+ C L HL L V L ++ Sbjct: 256 LTREASIKLSPLHGKQISIRYLDMTDCFV-LEDEGLHTIAAHCTQLTHLYLRRCVRLTDE 314 Query: 327 CFQEF-FQLNYLQHLSLSRCYDIIPETLLLVTRAGVRIRLDSDIGC 371 + ++ LS+S C + L + + R+R S C Sbjct: 315 GLRYLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHC 360 Score = 57.0 bits (136), Expect = 3e-08 Identities = 69/251 (27%), Positives = 119/251 (47%), Gaps = 18/251 (7%) Query: 113 CLPEL--LKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFM 170 C PEL L+VSG Y + S+E+++ + L H DV+G I+ S Sbjct: 210 CCPELRRLEVSGC----YNI-SNEAVFDVVSLCPNLEHLDVSG-CSKVTCISLTREASIK 263 Query: 171 DQPLAEHFSPFRVQHMDLSNS-VIEVSTLHGILSQCSKLQNLSLEG-LRLSDPIVNTLAK 228 PL H ++++D+++ V+E LH I + C++L +L L +RL+D + L Sbjct: 264 LSPL--HGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVI 321 Query: 229 N-SNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQ 287 +++ L++S C S+F L+ + SRL L+++ C T+ ++ + S+ + Sbjct: 322 YCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSK-LRY 380 Query: 288 LNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLN--YLQHLSLSRC 345 LN G + + + L + C L LD+ L +D E LN L+ LSL C Sbjct: 381 LNARGC-EGITDHGVEYLAKNCTKLKSLDIG-KCPLVSDTGLECLALNCFNLKRLSLKSC 438 Query: 346 YDIIPETLLLV 356 I + L +V Sbjct: 439 ESITGQGLQIV 449 Score = 35.4 bits (80), Expect = 0.094 Identities = 26/75 (34%), Positives = 38/75 (50%), Gaps = 5/75 (6%) Query: 197 TLHGI---LSQCSKLQNLSLEGLRL-SDPIVNTLAKNS-NLVRLNLSGCSGFSEFALQTL 251 T HG+ C+KL++L + L SD + LA N NL RL+L C + LQ + Sbjct: 390 TDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKSCESITGQGLQIV 449 Query: 252 LSSCSRLDELNLSWC 266 ++C L LN+ C Sbjct: 450 AANCFDLQTLNVQDC 464 >gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [Homo sapiens] Length = 1336 Score = 57.4 bits (137), Expect = 2e-08 Identities = 67/286 (23%), Positives = 122/286 (42%), Gaps = 55/286 (19%) Query: 103 ELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTG-KNLHPDVTGRLLSQGVI 161 E+ + +FS L +L VC+ W R D+ LW +DL K++ P L+ G+I Sbjct: 1068 EVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITP-----LMLSGII 1122 Query: 162 AFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGIL--------------SQCSK 207 QP++ S + LS + + L ++ S C Sbjct: 1123 --------RRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPL 1174 Query: 208 LQNLS---LEGLR-------LSDPIVN------TLAKNSNLVRLNLSGCSGFSEFALQTL 251 L+ L +EGL+ LS P N +K N+V L L+G ++ +L+ + Sbjct: 1175 LRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLD-ITDASLRLI 1233 Query: 252 LSSCSRLDELNLSWCFDFTEKHVQVAVA---HVSETITQLNLSGYRKNLQKSDLSTLVRR 308 + L +L+LS+C T++ + + A +++T++NLS K + +R Sbjct: 1234 IRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNK--VTDQCLSFFKR 1291 Query: 309 CPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLL 354 C N+ H+DL + + ++F + +S+S + + E LL Sbjct: 1292 CGNICHIDLRYCKQVTKEGCEQF-----IAEMSVSVQFGQVEEKLL 1332 >gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [Homo sapiens] Length = 1265 Score = 57.4 bits (137), Expect = 2e-08 Identities = 67/276 (24%), Positives = 117/276 (42%), Gaps = 51/276 (18%) Query: 103 ELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTG-KNLHPDVTGRLLSQGVI 161 E+ + +FS L +L VC+ W R D+ LW +DL K++ P L+ G+I Sbjct: 999 EVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNHCKSITP-----LMLSGII 1053 Query: 162 AFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGIL--------------SQCSK 207 QP++ S + LS + + L ++ S C Sbjct: 1054 --------RRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSSCPL 1105 Query: 208 LQNLS---LEGLR-------LSDPIVN------TLAKNSNLVRLNLSGCSGFSEFALQTL 251 L+ L +EGL+ LS P N +K N+V L L+G ++ +L+ + Sbjct: 1106 LRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLD-ITDASLRLI 1164 Query: 252 LSSCSRLDELNLSWCFDFTEKHVQVAVA---HVSETITQLNLSGYRKNLQKSDLSTLVRR 308 + L +L+LS+C T++ + + A +++T++NLS K + +R Sbjct: 1165 IRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNK--VTDQCLSFFKR 1222 Query: 309 CPNLVHLDLS-DSVMLKNDCFQEFFQLNYLQHLSLS 343 C N+ H+DL + K C Q +++ Q S S Sbjct: 1223 CGNICHIDLRYCKQVTKEGCEQFIAEMSSFQGRSCS 1258 >gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens] Length = 621 Score = 55.8 bits (133), Expect = 7e-08 Identities = 83/320 (25%), Positives = 133/320 (41%), Gaps = 73/320 (22%) Query: 97 WDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLL 156 +D LP EL+ I + L LP+L +++ CK LL Sbjct: 280 FDKLPYELIQLILNHLTLPDLCRLAQTCK-----------------------------LL 310 Query: 157 SQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSN--SVIEVSTLHGILSQCSKLQ--NLS 212 SQ P + H++L + ++ ++L + S+C+ +Q NLS Sbjct: 311 SQHCC-----------------DPLQYIHLNLQPYWAKLDDTSLEFLQSRCTLVQWLNLS 353 Query: 213 LEGLR--LSDPIVNTLAK--NSNLVRLNLSGCSGF-SEFALQTLLSSCSRLDELNLSWCF 267 G R +S + K S LVRL LS CS F +E L+ + C L LNLS C Sbjct: 354 WTGNRGFISVAGFSRFLKVCGSELVRLELS-CSHFLNETCLEVISEMCPNLQALNLSSC- 411 Query: 268 DFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKN-D 326 +K A H+++ + L YR ++++ L +++ C L HL L VM+++ D Sbjct: 412 ---DKLPPQAFNHIAKLCSLKRLVLYRTKVEQTALLSILNFCSELQHLSLGSCVMIEDYD 468 Query: 327 CFQEFF--QLNYLQHLSLSRCYDIIPETLLLVTRAGVRIRLDSDIG-CPQ--------TY 375 + L+ L L RC + I E + +G + + D+G CP T Sbjct: 469 VIASMIGAKCKKLRTLDLWRCKN-ITENGIAELASGCPLLEELDLGWCPTLQSSTGCFTR 527 Query: 376 RTSKLKSSHKLFCQHVRVIC 395 +L + KLF R +C Sbjct: 528 LAHQLPNLQKLFLTANRSVC 547 Score = 50.4 bits (119), Expect = 3e-06 Identities = 47/172 (27%), Positives = 80/172 (46%), Gaps = 7/172 (4%) Query: 183 VQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLS---DPIVNTL-AKNSNLVRLNLS 238 ++ + L + +E + L IL+ CS+LQ+LSL + D I + + AK L L+L Sbjct: 428 LKRLVLYRTKVEQTALLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLW 487 Query: 239 GCSGFSEFALQTLLSSCSRLDELNLSWCFDF-TEKHVQVAVAHVSETITQLNLSGYRKNL 297 C +E + L S C L+EL+L WC + +AH + +L L+ R ++ Sbjct: 488 RCKNITENGIAELASGCPLLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTANR-SV 546 Query: 298 QKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQ-LNYLQHLSLSRCYDI 348 +D+ L C L LD+ + M+ ++ + L L +S C I Sbjct: 547 CDTDIDELACNCTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQI 598 Score = 30.4 bits (67), Expect = 3.0 Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 2/73 (2%) Query: 204 QCSKLQNLSLEGLR-LSDPIVNTLAKN-SNLVRLNLSGCSGFSEFALQTLLSSCSRLDEL 261 Q LQ L L R + D ++ LA N + L +L++ G S +L+ LL SC L L Sbjct: 531 QLPNLQKLFLTANRSVCDTDIDELACNCTRLQQLDILGTRMVSPASLRKLLESCKDLSLL 590 Query: 262 NLSWCFDFTEKHV 274 ++S+C + V Sbjct: 591 DVSFCSQIDNRAV 603 >gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens] Length = 1162 Score = 52.4 bits (124), Expect = 7e-07 Identities = 64/291 (21%), Positives = 116/291 (39%), Gaps = 55/291 (18%) Query: 96 SWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTG-KNLHPDVTGR 154 SW + E+ + +F L EL + VCK WY+ D+ LW +DL+ K + P Sbjct: 891 SW--MQREVWMSVFRYLSRRELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSG 948 Query: 155 LLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGIL------------ 202 ++ + QP++ S + L+ V + L +L Sbjct: 949 IIKR-------------QPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSAL 995 Query: 203 --SQCSKLQNLSLE-GLRLSDPIVNTL-------------AKNSNLVRLNLSGCSGFSEF 246 S C L+ L L + + DP + L +K N+ L+G ++ Sbjct: 996 STSSCPLLRTLDLRWAVGIKDPQIRDLLTPPADKPGQDNRSKLRNMTDFRLAGLD-ITDA 1054 Query: 247 ALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSET---ITQLNLSGYRKNLQKSDLS 303 L+ ++ L L+LS C T++ + A S T +T+LN++G K ++ + Sbjct: 1055 TLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLI- 1113 Query: 304 TLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLL 354 +RR N+ +DL + + F + LS++ Y + E L+ Sbjct: 1114 -YLRRIANVTLIDLRGCKQITRKACEHF-----ISDLSINSLYCLSDEKLI 1158 >gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens] Length = 326 Score = 52.4 bits (124), Expect = 7e-07 Identities = 26/57 (45%), Positives = 35/57 (61%) Query: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLL 156 LPD +LL IFS L + + +++S VC RW RL D LW+ +DLT + P V LL Sbjct: 7 LPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLYTMRPKVMWHLL 63 >gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 [Homo sapiens] Length = 690 Score = 51.2 bits (121), Expect = 2e-06 Identities = 95/400 (23%), Positives = 158/400 (39%), Gaps = 80/400 (20%) Query: 77 KDFVIVRRPKLNRENFPGVSWDS--------------LPDELLLGIFSCLCLPELLKVSG 122 K+ +I++R NFP S LP+ +L IF L L +++ Sbjct: 121 KNRLILKRAAAEESNFPERSSSEVFLVDETLKCDISLLPERAILQIFFYLSLKDVIICGQ 180 Query: 123 VCKRWYRLASDESLWQTLDLTG-KNLHPDV------------TGRLLSQGVI----AFR- 164 V W + SLW +D + KN+ PD RL +G + FR Sbjct: 181 VNHAWMLMTQLNSLWNAIDFSSVKNVIPDKYIVSTLQRWRLNVLRLNFRGCLLRPKTFRS 240 Query: 165 --------------CPRSFMDQPLAEHFSPF--RVQHMDLSNSVIEVSTLHGILSQCSKL 208 CP +F D+ + H S V ++LSN+ I T+ + L Sbjct: 241 VSHCRNLQELNVSDCP-TFTDESM-RHISEGCPGVLCLNLSNTTITNRTMRLLPRHFHNL 298 Query: 209 QNLSLEGLR-LSDPIVNTLAKNSN---LVRLNLSGCSGFSEFALQTLLSSCSRLDELNLS 264 QNLSL R +D + L + L+ L+LSGC+ S + + +SC+ + L ++ Sbjct: 299 QNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRYIANSCTGIMHLTIN 358 Query: 265 WCFDFTEKHVQVAV--------------AHVSE-TITQLNLSGYRK-----NLQKSDLS- 303 T+ V+ V H+S+ T L+ RK N + +D S Sbjct: 359 DMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTFRALSACKLRKIRFEGNKRVTDASF 418 Query: 304 -TLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETL--LLVTRAG 360 + + PNL H+ ++D + + + L L L+L+ C I L L A Sbjct: 419 KFIDKNYPNLSHIYMADCKGITDSSLRSLSPLKQLTVLNLANCVRIGDMGLKQFLDGPAS 478 Query: 361 VRIRLDSDIGCPQTYRTSKLKSSHKLFCQHVRVICIFVCD 400 +RIR + C + S +K S + C ++ + + C+ Sbjct: 479 MRIRELNLSNCVRLSDASVMKLSER--CPNLNYLSLRNCE 516 Score = 38.5 bits (88), Expect = 0.011 Identities = 35/131 (26%), Positives = 64/131 (48%), Gaps = 20/131 (15%) Query: 164 RCPR-SFMDQPLAEHFSP---------FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSL 213 RCP +++ EH + F + +DLS + I L+ +LS+ KL+ LS+ Sbjct: 503 RCPNLNYLSLRNCEHLTAQGIGYIVNIFSLVSIDLSGTDISNEGLN-VLSRHKKLKELSV 561 Query: 214 --------EGLRLSDPIVNTL-AKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLS 264 +G++++D + L AK L L++SGC ++ L+ L C +L L + Sbjct: 562 SECYRITDDGIQITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLRILKMQ 621 Query: 265 WCFDFTEKHVQ 275 +C + ++K Q Sbjct: 622 YCTNISKKAAQ 632 Score = 31.6 bits (70), Expect = 1.4 Identities = 40/147 (27%), Positives = 63/147 (42%), Gaps = 24/147 (16%) Query: 235 LNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYR 294 LNLS C S+ ++ L C L+ L+L C T + + V S + ++LSG Sbjct: 484 LNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNIFS--LVSIDLSG-- 539 Query: 295 KNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQ------EFF--QLNYLQHLSLSRCY 346 ++ L+ L R L L +S+ + +D Q E + +YL L +S C Sbjct: 540 TDISNEGLNVLSRH-KKLKELSVSECYRITDDGIQITDSAMEMLSAKCHYLHILDISGC- 597 Query: 347 DIIPETLLLVTRAGVRIRLDSDIGCPQ 373 +L+T +I D IGC Q Sbjct: 598 -------VLLTD---QILEDLQIGCKQ 614 >gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 [Homo sapiens] Length = 735 Score = 51.2 bits (121), Expect = 2e-06 Identities = 95/400 (23%), Positives = 158/400 (39%), Gaps = 80/400 (20%) Query: 77 KDFVIVRRPKLNRENFPGVSWDS--------------LPDELLLGIFSCLCLPELLKVSG 122 K+ +I++R NFP S LP+ +L IF L L +++ Sbjct: 121 KNRLILKRAAAEESNFPERSSSEVFLVDETLKCDISLLPERAILQIFFYLSLKDVIICGQ 180 Query: 123 VCKRWYRLASDESLWQTLDLTG-KNLHPDV------------TGRLLSQGVI----AFR- 164 V W + SLW +D + KN+ PD RL +G + FR Sbjct: 181 VNHAWMLMTQLNSLWNAIDFSSVKNVIPDKYIVSTLQRWRLNVLRLNFRGCLLRPKTFRS 240 Query: 165 --------------CPRSFMDQPLAEHFSPF--RVQHMDLSNSVIEVSTLHGILSQCSKL 208 CP +F D+ + H S V ++LSN+ I T+ + L Sbjct: 241 VSHCRNLQELNVSDCP-TFTDESM-RHISEGCPGVLCLNLSNTTITNRTMRLLPRHFHNL 298 Query: 209 QNLSLEGLR-LSDPIVNTLAKNSN---LVRLNLSGCSGFSEFALQTLLSSCSRLDELNLS 264 QNLSL R +D + L + L+ L+LSGC+ S + + +SC+ + L ++ Sbjct: 299 QNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRYIANSCTGIMHLTIN 358 Query: 265 WCFDFTEKHVQVAV--------------AHVSE-TITQLNLSGYRK-----NLQKSDLS- 303 T+ V+ V H+S+ T L+ RK N + +D S Sbjct: 359 DMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTFRALSACKLRKIRFEGNKRVTDASF 418 Query: 304 -TLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETL--LLVTRAG 360 + + PNL H+ ++D + + + L L L+L+ C I L L A Sbjct: 419 KFIDKNYPNLSHIYMADCKGITDSSLRSLSPLKQLTVLNLANCVRIGDMGLKQFLDGPAS 478 Query: 361 VRIRLDSDIGCPQTYRTSKLKSSHKLFCQHVRVICIFVCD 400 +RIR + C + S +K S + C ++ + + C+ Sbjct: 479 MRIRELNLSNCVRLSDASVMKLSER--CPNLNYLSLRNCE 516 Score = 48.9 bits (115), Expect = 8e-06 Identities = 36/150 (24%), Positives = 74/150 (49%), Gaps = 3/150 (2%) Query: 200 GILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLD 259 G + L ++ L G +S+ +N L+++ L L++S C ++ +Q S L+ Sbjct: 524 GYIVNIFSLVSIDLSGTDISNEGLNVLSRHKKLKELSVSECYRITDDGIQAFCKSSLILE 583 Query: 260 ELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSD 319 L++S+C ++ ++ A+A +T L+++G K + S + L +C L LD+S Sbjct: 584 HLDVSYCSQLSDMIIK-ALAIYCINLTSLSIAGCPK-ITDSAMEMLSAKCHYLHILDISG 641 Query: 320 SVMLKNDCFQEF-FQLNYLQHLSLSRCYDI 348 V+L + ++ L+ L + C +I Sbjct: 642 CVLLTDQILEDLQIGCKQLRILKMQYCTNI 671 Score = 42.7 bits (99), Expect = 6e-04 Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 8/166 (4%) Query: 235 LNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYR 294 LNLS C S+ ++ L C L+ L+L C T + + V S + ++LSG Sbjct: 484 LNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNIFS--LVSIDLSG-- 539 Query: 295 KNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLN-YLQHLSLSRCYDIIPETL 353 ++ L+ L R L L +S+ + +D Q F + + L+HL +S C + + Sbjct: 540 TDISNEGLNVLSRH-KKLKELSVSECYRITDDGIQAFCKSSLILEHLDVSYCSQLSDMII 598 Query: 354 LLVTRAGVRIRLDSDIGCPQTYRTSKLKSSHKLFCQHVRVICIFVC 399 + + + S GCP+ ++ S K C ++ ++ I C Sbjct: 599 KALAIYCINLTSLSIAGCPKITDSAMEMLSAK--CHYLHILDISGC 642 Score = 36.2 bits (82), Expect = 0.055 Identities = 26/96 (27%), Positives = 50/96 (52%), Gaps = 3/96 (3%) Query: 183 VQHMDLSN-SVIEVSTLHGILSQCSKLQNLSLEGL-RLSDPIVNTL-AKNSNLVRLNLSG 239 ++H+D+S S + + + C L +LS+ G +++D + L AK L L++SG Sbjct: 582 LEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISG 641 Query: 240 CSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQ 275 C ++ L+ L C +L L + +C + ++K Q Sbjct: 642 CVLLTDQILEDLQIGCKQLRILKMQYCTNISKKAAQ 677 >gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [Homo sapiens] Length = 539 Score = 51.2 bits (121), Expect = 2e-06 Identities = 48/185 (25%), Positives = 77/185 (41%), Gaps = 36/185 (19%) Query: 85 PKLNRENFPGVSW-DSLPDELLLGIFSCLC-----LPELLKVSGVCKRWYRLASDESLWQ 138 P E P W D +P E+L+ IF L +P L + + VC+RW AS +LW Sbjct: 99 PTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWH 158 Query: 139 TLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTL 198 T+ L+ + GR GV A + + ++ + FS ++Q + L + +V + Sbjct: 159 TVTLSS-----PLVGRPAKGGVKAEKKLLASLEWLMPNRFS--QLQRLTLIHWKSQVHPV 211 Query: 199 HGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRL 258 ++ +C L L LSGC G + AL L +C +L Sbjct: 212 LKLVGECC-----------------------PRLTFLKLSGCHGVTADALVMLAKACCQL 248 Query: 259 DELNL 263 L+L Sbjct: 249 HSLDL 253 >gi|190194416 F-box and leucine-rich repeat protein 15 [Homo sapiens] Length = 300 Score = 50.8 bits (120), Expect = 2e-06 Identities = 50/201 (24%), Positives = 84/201 (41%), Gaps = 31/201 (15%) Query: 196 STLHGILSQCSKLQNLSLEGLR--LSDP-IVNTLAKNSNLVRLNLSGCSGFSEFALQTLL 252 + L +L LQ L+L LSD +V LA+N L + L GC S AL L Sbjct: 77 AALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALA 136 Query: 253 SSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRK----------------- 295 C RL L+L+ C D+ + +A + +L+L+ R+ Sbjct: 137 EGCPRLQRLSLAHC-DWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGL 195 Query: 296 ---------NLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQ-LNYLQHLSLSRC 345 N+ + + L R CP L HLDL+ + + +D + + L+ L + C Sbjct: 196 RSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHC 255 Query: 346 YDIIPETLLLVTRAGVRIRLD 366 + + +L + + GV I ++ Sbjct: 256 HHVAESSLSRLRKRGVDIDVE 276 >gi|148922963 F-box and leucine-rich repeat protein 21 [Homo sapiens] Length = 434 Score = 48.9 bits (115), Expect = 8e-06 Identities = 49/201 (24%), Positives = 82/201 (40%), Gaps = 31/201 (15%) Query: 95 VSWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLW--------QTLDLTGKN 146 + W SLP ++L IF L L + S VC+RW + LW Q+ + K+ Sbjct: 40 LDWGSLPHHVVLQIFQYLPLLDRACASSVCRRWNEVFHISDLWRKFEFELNQSATSSFKS 99 Query: 147 LHPDVTGRLLSQ-----GVIAFRCPRSFMDQPLA---------------EHFSPFRVQHM 186 HPD+ +++ + ++F+ S A S + M Sbjct: 100 THPDLIQQIIKKHFAHLQYVSFKVDSSAESAEAACDILSQLVNCSIQTLGLISTAKPSFM 159 Query: 187 DLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTL-AKNSNLVRL-NLSGCSGFS 244 ++S S VS L + L ++ +E + DP + L A NS+ +RL +S C S Sbjct: 160 NVSESHF-VSALTVVFINSKSLSSIKIEDTPVDDPSLKILVANNSDTLRLPKMSSCPHVS 218 Query: 245 EFALQTLLSSCSRLDELNLSW 265 + + C L EL L++ Sbjct: 219 SDGILCVADRCQGLRELALNY 239 >gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapiens] Length = 694 Score = 47.8 bits (112), Expect = 2e-05 Identities = 95/378 (25%), Positives = 137/378 (36%), Gaps = 101/378 (26%) Query: 6 LQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEP-DSENIPQELLSNLGHPES 64 L+ +PD SS+ + S DS S G S E E P ++ N + + G E+ Sbjct: 317 LERVPDTSSSSSDS-----DSDSDSS-----GTSLSEDEAPGEARNGRRPARGSSGEKEN 366 Query: 65 PPRKRLKSKGSDKDFV------------------IVRRPKLNREN----FPGVSWDSLPD 102 +R GS + +VR P + E S LP Sbjct: 367 RGGRRAVRPGSGGPLLSWPLGPAPPPRPPQLERHVVRPPPRSPEPDTLPLAAGSDHPLPR 426 Query: 103 ELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIA 162 L +F L EL VC+ W R D+ LW +DL+ + +T +LS GV+ Sbjct: 427 AAWLRVFQHLGPRELCICMRVCRTWSRWCYDKRLWPRMDLSRRK---SLTPPMLS-GVVR 482 Query: 163 FRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEG------- 215 R PR+ +DLS + + L +L++ LQ L L G Sbjct: 483 -RQPRA-----------------LDLSWTGVSKKQLMWLLNRLQGLQELVLSGCSWLSVS 524 Query: 216 ---------LRLSDPIVNTLAKNSNL------------------------VRLNLSGCSG 242 LRL D K+S L L L+G Sbjct: 525 ALGSAPLPALRLLDLRWIEDVKDSQLRELLLPPPDTKPGQTESRGRLQGVAELRLAGLE- 583 Query: 243 FSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVS---ETITQLNLSGYRKNLQK 299 ++ +L+ LL +L L+LS C + V + A S ET+ LNL+G + Sbjct: 584 LTDASLRLLLRHAPQLSALDLSHCAHVGDPSVHLLTAPTSPLRETLVHLNLAGCHR--LT 641 Query: 300 SDLSTLVRRCPNLVHLDL 317 L RRCP L LDL Sbjct: 642 DHCLPLFRRCPRLRRLDL 659 >gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [Homo sapiens] Length = 533 Score = 46.6 bits (109), Expect = 4e-05 Identities = 49/185 (26%), Positives = 73/185 (39%), Gaps = 42/185 (22%) Query: 85 PKLNRENFPGVSW-DSLPDELLLGIFSCLC-----LPELLKVSGVCKRWYRLASDESLWQ 138 P E P W D +P E+L+ IF L +P L + + VC+RW AS +LW Sbjct: 99 PTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWH 158 Query: 139 TLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTL 198 T+ L+ + GR GV A + + ++ + F Sbjct: 159 TVTLSS-----PLVGRPAKGGVKAEKKLLASLEWLMPNRF-------------------- 193 Query: 199 HGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRL 258 S+LQ L+L + +V L L LSGC G + AL L +C +L Sbjct: 194 -------SQLQRLTL--IHWKSQLVGECC--PRLTFLKLSGCHGVTADALVMLAKACCQL 242 Query: 259 DELNL 263 L+L Sbjct: 243 HSLDL 247 >gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens] Length = 223 Score = 46.6 bits (109), Expect = 4e-05 Identities = 51/177 (28%), Positives = 79/177 (44%), Gaps = 17/177 (9%) Query: 198 LHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTL-LSSCS 256 +HG SQ + L L+ S P + A + G S + ALQ L L++CS Sbjct: 28 MHGAPSQLASLSLAHCSSLK-SRPELEHQASGTKDACPEPQGPSLLTLRALQELDLTACS 86 Query: 257 RLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLD 316 +L + +L+ F + + QL+LS L + L + R CP+L HL Sbjct: 87 KLTDASLAKVLQFLQ-------------LRQLSLS-LLPELTDNGLVAVARGCPSLEHLA 132 Query: 317 LSDSVMLKNDCF-QEFFQLNYLQHLSLSRCYDIIPETLLLVTRAGVRIRLDSDIGCP 372 LS L + + Q LQHL+LS C +I +TL + +A ++R+ CP Sbjct: 133 LSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCP 189 >gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens] Length = 223 Score = 46.6 bits (109), Expect = 4e-05 Identities = 51/177 (28%), Positives = 79/177 (44%), Gaps = 17/177 (9%) Query: 198 LHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTL-LSSCS 256 +HG SQ + L L+ S P + A + G S + ALQ L L++CS Sbjct: 28 MHGAPSQLASLSLAHCSSLK-SRPELEHQASGTKDACPEPQGPSLLTLRALQELDLTACS 86 Query: 257 RLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLD 316 +L + +L+ F + + QL+LS L + L + R CP+L HL Sbjct: 87 KLTDASLAKVLQFLQ-------------LRQLSLS-LLPELTDNGLVAVARGCPSLEHLA 132 Query: 317 LSDSVMLKNDCF-QEFFQLNYLQHLSLSRCYDIIPETLLLVTRAGVRIRLDSDIGCP 372 LS L + + Q LQHL+LS C +I +TL + +A ++R+ CP Sbjct: 133 LSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCP 189 >gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens] Length = 479 Score = 46.2 bits (108), Expect = 5e-05 Identities = 63/275 (22%), Positives = 114/275 (41%), Gaps = 18/275 (6%) Query: 102 DELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVI 161 +++L G+F E ++ VCK W R+ W L LH +L G Sbjct: 99 EKILNGLFWYFSACEKCVLAQVCKAWRRVLYQPKFWAGLTPV---LHAKELYNVLPGGEK 155 Query: 162 AFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVS-TLHGILSQCSKLQNLSLEGLRLSD 220 F + F + E F V +D+ + + + G+ + K ++ GL + Sbjct: 156 EFVNLQGFAARGF-EGFCLVGVSDLDICEFIDNYALSKKGVKAMSLKRSTITDAGLEVM- 213 Query: 221 PIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAH 280 L + +VRL LSGC+ F+E L + LS +R+ L++S C + + + A++ Sbjct: 214 -----LEQMQGVVRLELSGCNDFTEAGLWSSLS--ARITSLSVSDCINVADDAI-AAISQ 265 Query: 281 VSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHL--DLSDSVMLKNDCFQEFFQLNYLQ 338 + + +L+L Y ++ + L+ R + H LS + + L L Sbjct: 266 LLPNLAELSLQAY--HVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLT 323 Query: 339 HLSLSRCYDIIPETLLLVTRAGVRIRLDSDIGCPQ 373 LSLS C + + + LV ++R CP+ Sbjct: 324 ALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPR 358 Score = 38.1 bits (87), Expect = 0.015 Identities = 44/161 (27%), Positives = 72/161 (44%), Gaps = 11/161 (6%) Query: 197 TLHGILSQCSKLQNL---SLEGL-RLSDPIVNTLAKNSNLVR-LNLSGCSGFSEFALQTL 251 T HG+++ L NL SL G +++D V +A+N +R L+LS C ++ AL+ + Sbjct: 308 TNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYV 367 Query: 252 LSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTL-VRRCP 310 RL+EL L C T+ ++++S T++ L R Q D + Sbjct: 368 ACDLHRLEELVLDRCVRITD----TGLSYLS-TMSSLRSLYLRWCCQVQDFGLKHLLALG 422 Query: 311 NLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPE 351 +L L + +L QL L+ L L+ C PE Sbjct: 423 SLRLLSPAGCPLLTTTGLSGLVQLQELEELELTNCPGATPE 463 >gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens] Length = 843 Score = 43.5 bits (101), Expect = 3e-04 Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 5/58 (8%) Query: 98 DSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTL-----DLTGKNLHPD 150 + LPDE++L IFS L +L + + VCKR+ LA+D LW+ L + T +HP+ Sbjct: 73 EKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPE 130 >gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens] Length = 686 Score = 43.5 bits (101), Expect = 3e-04 Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 5/58 (8%) Query: 98 DSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTL-----DLTGKNLHPD 150 + LPDE++L IFS L +L + + VCKR+ LA+D LW+ L + T +HP+ Sbjct: 73 EKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPE 130 >gi|30089922 F-box only protein 11 isoform 3 [Homo sapiens] Length = 585 Score = 43.5 bits (101), Expect = 3e-04 Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 5/58 (8%) Query: 98 DSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTL-----DLTGKNLHPD 150 + LPDE++L IFS L +L + + VCKR+ LA+D LW+ L + T +HP+ Sbjct: 73 EKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPE 130 >gi|164663798 antagonist of mitotic exit network 1 homolog [Homo sapiens] Length = 258 Score = 42.7 bits (99), Expect = 6e-04 Identities = 46/205 (22%), Positives = 94/205 (45%), Gaps = 27/205 (13%) Query: 187 DLSNSVIEVSTLHGILSQCS-------KLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSG 239 ++ + +I++ ++ G ++ + ++Q L L +SD + L+ L +LNL+ Sbjct: 35 NIKDRLIKIMSMQGQITDSNISEILHPEVQTLDLRSCDISDAALLHLSNCRKLKKLNLNA 94 Query: 240 CSG----FSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRK 295 G + ++ + SSCS L E +L C + T++ V VA+A + + ++L G Sbjct: 95 SKGNRVSVTSEGIKAVASSCSYLHEASLKRCCNLTDEGV-VALALNCQLLKIIDLGGC-L 152 Query: 296 NLQKSDLSTLVRRCPNLVHLD-----LSDS---VMLKNDCFQEFFQLNYLQHLSLSRCYD 347 ++ L L + CP L +D +SDS ++ C ++ L+ + + C + Sbjct: 153 SITDVSLHALGKNCPFLQCVDFSATQVSDSGVIALVSGPCAKK------LEEIHMGHCVN 206 Query: 348 IIPETLLLVTRAGVRIRLDSDIGCP 372 + + V +IR+ GCP Sbjct: 207 LTDGAVEAVLTYCPQIRILLFHGCP 231 >gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens] Length = 418 Score = 41.2 bits (95), Expect = 0.002 Identities = 60/282 (21%), Positives = 119/282 (42%), Gaps = 32/282 (11%) Query: 103 ELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLD--LTGKNLHPDVTGRLLSQG- 159 ELL IF L + + + + VC W A +S+W+ ++ L + +P + L ++G Sbjct: 11 ELLAMIFGYLDVRDKGRAAQVCTAWRDAAYHKSVWRGVEAKLHLRRANPSLFPSLQARGI 70 Query: 160 ----VIAFRCPRSFMDQPLAEHFSPFRVQHMDLSN--SVIEVSTLHGILSQCSKLQNLSL 213 +++ R S++ Q +A ++ ++LS ++ + H + + L+ L+L Sbjct: 71 RRVQILSLRRSLSYVIQGMA------NIESLNLSGCYNLTDNGLGHAFVQEIGSLRALNL 124 Query: 214 EGLR-LSDPIVNTLAKN-SNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTE 271 + ++D + +A+ L L L GCS + L + RL LNL C ++ Sbjct: 125 SLCKQITDSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSCRHLSD 184 Query: 272 KHVQVAVAHVSET----------ITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSV 321 V + H++ + QL L +K L L + R L L+LS Sbjct: 185 ----VGIGHLAGMTRSAAEGCLGLEQLTLQDCQK-LTDLSLKHISRGLTGLRLLNLSFCG 239 Query: 322 MLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLLVTRAGVRI 363 + + + L+ L+L C +I ++ + +R+ Sbjct: 240 GISDAGLLHLSHMGSLRSLNLRSCDNISDTGIMHLAMGSLRL 281 Score = 36.6 bits (83), Expect = 0.042 Identities = 43/175 (24%), Positives = 78/175 (44%), Gaps = 22/175 (12%) Query: 202 LSQCSKLQNLSLE-------GLRL---------SDPIVNTLAKNSNLVRLNLSGCSGFSE 245 L C KL +LSL+ GLRL SD + L+ +L LNL C S+ Sbjct: 209 LQDCQKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGLLHLSHMGSLRSLNLRSCDNISD 268 Query: 246 FALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQL-NLSGYRKNLQKSDLST 304 + L RL L++S+C +K ++A++++ + L +LS ++ ++ Sbjct: 269 TGIMHLAMGSLRLSGLDVSFC----DKVGDQSLAYIAQGLDGLKSLSLCSCHISDDGINR 324 Query: 305 LVRRCPNLVHLDLSDSVMLKNDCFQEFFQ-LNYLQHLSLSRCYDIIPETLLLVTR 358 +VR+ L L++ V + + + + L+ L + L C I L +T+ Sbjct: 325 MVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQLTGIDLYGCTRITKRGLERITQ 379 >gi|229576894 F-box and WD repeat domain containing 12 isoform 2 [Homo sapiens] Length = 394 Score = 39.3 bits (90), Expect = 0.007 Identities = 22/43 (51%), Positives = 27/43 (62%) Query: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDL 142 LPD L IFS L L LL+VS V K W R+A + LW++L L Sbjct: 5 LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47 >gi|229576873 F-box and WD repeat domain containing 12 isoform 1 [Homo sapiens] Length = 464 Score = 39.3 bits (90), Expect = 0.007 Identities = 22/43 (51%), Positives = 27/43 (62%) Query: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDL 142 LPD L IFS L L LL+VS V K W R+A + LW++L L Sbjct: 5 LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47 >gi|219281831 F-box protein 15 isoform 2 [Homo sapiens] Length = 510 Score = 37.0 bits (84), Expect = 0.032 Identities = 18/40 (45%), Positives = 24/40 (60%) Query: 98 DSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLW 137 D +P E+LL IFS L LL V +R+Y LA+D +W Sbjct: 75 DGMPSEILLKIFSYLDAVSLLCTGCVSRRFYHLANDNFIW 114 >gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [Homo sapiens] Length = 565 Score = 37.0 bits (84), Expect = 0.032 Identities = 56/232 (24%), Positives = 87/232 (37%), Gaps = 37/232 (15%) Query: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTL-------------DLTGKN 146 LP E++L IFS L EL + S V +W +L SLW+ L T + Sbjct: 82 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHWARGDWYSGPATELD 141 Query: 147 LHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCS 206 PD + R + + + + + +S + +E LHG++ Sbjct: 142 TEPD--DEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHGLIHNVL 199 Query: 207 KLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGF------------SEFALQTLLSS 254 S++ L L+ + A +S +VR L C S F + L Sbjct: 200 PYVGTSVKTLVLA----YSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWLGC 255 Query: 255 CSRLDELNLSWCFDFTEKHVQVAVAHVSETITQL--NLSGYRKNLQKSDLST 304 C L L+LS C EK VA+ +S + L + SG+ K ST Sbjct: 256 CQSLRHLDLSGC----EKITDVALEKISRALGILTSHQSGFLKTSTSKITST 303 Score = 32.0 bits (71), Expect = 1.0 Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 5/83 (6%) Query: 280 HVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQL---NY 336 +V ++ L L+ Y + + ++ CPNL HLDL+ + + + F + L Sbjct: 201 YVGTSVKTLVLA-YSSAVSSKMVRQILELCPNLEHLDLTQT-DISDSAFDSWSWLGCCQS 258 Query: 337 LQHLSLSRCYDIIPETLLLVTRA 359 L+HL LS C I L ++RA Sbjct: 259 LRHLDLSGCEKITDVALEKISRA 281 Score = 32.0 bits (71), Expect = 1.0 Identities = 16/46 (34%), Positives = 23/46 (50%) Query: 232 LVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVA 277 L LNLSGC + LQ L+S+C L++ +C + H A Sbjct: 502 LEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADTA 547 >gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [Homo sapiens] Length = 691 Score = 37.0 bits (84), Expect = 0.032 Identities = 56/232 (24%), Positives = 87/232 (37%), Gaps = 37/232 (15%) Query: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTL-------------DLTGKN 146 LP E++L IFS L EL + S V +W +L SLW+ L T + Sbjct: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHWARGDWYSGPATELD 267 Query: 147 LHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLHGILSQCS 206 PD + R + + + + + +S + +E LHG++ Sbjct: 268 TEPD--DEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHGLIHNVL 325 Query: 207 KLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGF------------SEFALQTLLSS 254 S++ L L+ + A +S +VR L C S F + L Sbjct: 326 PYVGTSVKTLVLA----YSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWLGC 381 Query: 255 CSRLDELNLSWCFDFTEKHVQVAVAHVSETITQL--NLSGYRKNLQKSDLST 304 C L L+LS C EK VA+ +S + L + SG+ K ST Sbjct: 382 CQSLRHLDLSGC----EKITDVALEKISRALGILTSHQSGFLKTSTSKITST 429 Score = 32.0 bits (71), Expect = 1.0 Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 5/83 (6%) Query: 280 HVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQL---NY 336 +V ++ L L+ Y + + ++ CPNL HLDL+ + + + F + L Sbjct: 327 YVGTSVKTLVLA-YSSAVSSKMVRQILELCPNLEHLDLTQT-DISDSAFDSWSWLGCCQS 384 Query: 337 LQHLSLSRCYDIIPETLLLVTRA 359 L+HL LS C I L ++RA Sbjct: 385 LRHLDLSGCEKITDVALEKISRA 407 Score = 32.0 bits (71), Expect = 1.0 Identities = 16/46 (34%), Positives = 23/46 (50%) Query: 232 LVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVA 277 L LNLSGC + LQ L+S+C L++ +C + H A Sbjct: 628 LEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADTA 673 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.136 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,587,865 Number of Sequences: 37866 Number of extensions: 682458 Number of successful extensions: 2058 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 56 Number of HSP's successfully gapped in prelim test: 41 Number of HSP's that attempted gapping in prelim test: 1882 Number of HSP's gapped (non-prelim): 154 length of query: 410 length of database: 18,247,518 effective HSP length: 105 effective length of query: 305 effective length of database: 14,271,588 effective search space: 4352834340 effective search space used: 4352834340 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.