Search of human proteins with 14165431

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14165431 protocadherin alpha subfamily C, 2 isoform 2
precursor [Homo sapiens]
         (884 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precurs...  1748   0.0  
gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso...  1690   0.0  
gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precurs...   664   0.0  
gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precurs...   664   0.0  
gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]       654   0.0  
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]       652   0.0  
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs...   640   0.0  
gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precur...   640   0.0  
gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precurs...   629   e-180
gi|7662056 protocadherin gamma subfamily A, 8 isoform 2 precurso...   629   e-180
gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precurs...   622   e-178
gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precurs...   622   e-178
gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precur...   620   e-177
gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precur...   620   e-177
gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precurs...   618   e-177
gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precurs...   618   e-177
gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precurs...   617   e-176
gi|14270487 protocadherin gamma subfamily A, 9 isoform 2 precurs...   617   e-176
gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur...   617   e-176
gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precur...   617   e-176
gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precurs...   608   e-174
gi|14196465 protocadherin gamma subfamily A, 3 isoform 2 precurs...   608   e-174
gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precurs...   607   e-173
gi|14196459 protocadherin gamma subfamily A, 1 isoform 2 precurs...   607   e-173
gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precurs...   607   e-173
gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precurs...   607   e-173
gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi...   603   e-172
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]   603   e-172
gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precurs...   602   e-172
gi|14277675 protocadherin gamma subfamily C, 3 isoform 1 precurs...   602   e-172

>gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precursor
           [Homo sapiens]
          Length = 884

 Score = 1748 bits (4528), Expect = 0.0
 Identities = 884/884 (100%), Positives = 884/884 (100%)

Query: 1   MEQAGTRPAATEHPRLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGN 60
           MEQAGTRPAATEHPRLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGN
Sbjct: 1   MEQAGTRPAATEHPRLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGN 60

Query: 61  VARALGLELRRLGPGCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLS 120
           VARALGLELRRLGPGCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLS
Sbjct: 61  VARALGLELRRLGPGCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLS 120

Query: 121 LEVLAHNPVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGAN 180
           LEVLAHNPVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGAN
Sbjct: 121 LEVLAHNPVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGAN 180

Query: 181 SVQTYELSPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGT 240
           SVQTYELSPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGT
Sbjct: 181 SVQTYELSPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGT 240

Query: 241 AQISVRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYT 300
           AQISVRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYT
Sbjct: 241 AQISVRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYT 300

Query: 301 SDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVND 360
           SDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVND
Sbjct: 301 SDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVND 360

Query: 361 NAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYT 420
           NAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYT
Sbjct: 361 NAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYT 420

Query: 421 LVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQE 480
           LVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQE
Sbjct: 421 LVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQE 480

Query: 481 NNLPGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYE 540
           NNLPGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYE
Sbjct: 481 NNLPGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYE 540

Query: 541 KFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPA 600
           KFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPA
Sbjct: 541 KFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPA 600

Query: 601 GYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTV 660
           GYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTV
Sbjct: 601 GYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTV 660

Query: 661 VVRDNGEPSLSASVAITVAVVDRVSKILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFL 720
           VVRDNGEPSLSASVAITVAVVDRVSKILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFL
Sbjct: 661 VVRDNGEPSLSASVAITVAVVDRVSKILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFL 720

Query: 721 LTIIILSIIKCYRYTAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIE 780
           LTIIILSIIKCYRYTAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIE
Sbjct: 721 LTIIILSIIKCYRYTAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIE 780

Query: 781 VRGNGSLTKTYCYKACLTAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNA 840
           VRGNGSLTKTYCYKACLTAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNA
Sbjct: 781 VRGNGSLTKTYCYKACLTAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNA 840

Query: 841 GNLIILKNEAVSQNEVRQWSGGLLQTHAFVTHPPISCDLALLSH 884
           GNLIILKNEAVSQNEVRQWSGGLLQTHAFVTHPPISCDLALLSH
Sbjct: 841 GNLIILKNEAVSQNEVRQWSGGLLQTHAFVTHPPISCDLALLSH 884


>gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor
           [Homo sapiens]
          Length = 1007

 Score = 1690 bits (4377), Expect = 0.0
 Identities = 857/858 (99%), Positives = 857/858 (99%)

Query: 1   MEQAGTRPAATEHPRLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGN 60
           MEQAGTRPAATEHPRLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGN
Sbjct: 1   MEQAGTRPAATEHPRLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGN 60

Query: 61  VARALGLELRRLGPGCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLS 120
           VARALGLELRRLGPGCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLS
Sbjct: 61  VARALGLELRRLGPGCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLS 120

Query: 121 LEVLAHNPVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGAN 180
           LEVLAHNPVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGAN
Sbjct: 121 LEVLAHNPVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGAN 180

Query: 181 SVQTYELSPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGT 240
           SVQTYELSPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGT
Sbjct: 181 SVQTYELSPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGT 240

Query: 241 AQISVRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYT 300
           AQISVRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYT
Sbjct: 241 AQISVRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYT 300

Query: 301 SDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVND 360
           SDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVND
Sbjct: 301 SDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVND 360

Query: 361 NAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYT 420
           NAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYT
Sbjct: 361 NAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYT 420

Query: 421 LVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQE 480
           LVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQE
Sbjct: 421 LVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQE 480

Query: 481 NNLPGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYE 540
           NNLPGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYE
Sbjct: 481 NNLPGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYE 540

Query: 541 KFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPA 600
           KFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPA
Sbjct: 541 KFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPA 600

Query: 601 GYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTV 660
           GYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTV
Sbjct: 601 GYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTV 660

Query: 661 VVRDNGEPSLSASVAITVAVVDRVSKILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFL 720
           VVRDNGEPSLSASVAITVAVVDRVSKILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFL
Sbjct: 661 VVRDNGEPSLSASVAITVAVVDRVSKILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFL 720

Query: 721 LTIIILSIIKCYRYTAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIE 780
           LTIIILSIIKCYRYTAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIE
Sbjct: 721 LTIIILSIIKCYRYTAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIE 780

Query: 781 VRGNGSLTKTYCYKACLTAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNA 840
           VRGNGSLTKTYCYKACLTAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNA
Sbjct: 781 VRGNGSLTKTYCYKACLTAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNA 840

Query: 841 GNLIILKNEAVSQNEVRQ 858
           GNLIILKNEAVSQNE RQ
Sbjct: 841 GNLIILKNEAVSQNEPRQ 858


>gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precursor
           [Homo sapiens]
          Length = 878

 Score =  664 bits (1712), Expect = 0.0
 Identities = 355/783 (45%), Positives = 505/783 (64%), Gaps = 10/783 (1%)

Query: 28  LLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSP 87
           +L +L L   G  + QLRYSV EE  PG LVGNVA+ LGL++  L    L++      + 
Sbjct: 15  VLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLG--SEENG 72

Query: 88  RYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPR 147
           RY  L L SGAL VN++IDRE+LC     CLL ++V+  +P+ +  VEVEILD+NDNSP 
Sbjct: 73  RYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPS 132

Query: 148 FPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVL 207
           F  P  ++++SES A GARF ++SAQDPDVG N+V  Y LSP+ HF L++K L++     
Sbjct: 133 FATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFP 192

Query: 208 ELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLR 267
           ELVL + LDRE  A H LVLTAVDGG PARSGT  ISV VLD NDN+P F  S  RV + 
Sbjct: 193 ELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIP 252

Query: 268 EDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEE 327
           E++P GTL+++LNA+DPDEG+NG+L YS   +TS+  R LF +D S+G + V+G +D+EE
Sbjct: 253 ENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEE 312

Query: 328 ASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVL 387
           +  Y+I+ +A D+G   M GHC + VD+ DVNDNAPEV+L  L +PV E+    T+V + 
Sbjct: 313 SRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLF 372

Query: 388 SVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIP 447
           +V D+DSG N +VSL +   LPF++    N Y+L+ S PLDRE  + Y I + A+D G P
Sbjct: 373 NVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHYIIELLASDAGSP 432

Query: 448 QLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYS 507
            L    T+++ ISD+NDN P F +  Y+ YI EN  PG LLCTV A+DPD  +NA +TYS
Sbjct: 433 SLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYS 492

Query: 508 LLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANV 567
           ++  ++QG P +S+V +N   G ++A  +FDYE  +   + V  +D GSPPL +  + +V
Sbjct: 493 IVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHV 552

Query: 568 YVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH-LAQ 626
           +V+D ND+AP +L+P      +A + +PR+AP G LVTKV A+D+D+G NAWL Y  L Q
Sbjct: 553 FVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQ 612

Query: 627 TSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSK 686
           ++   LF V  HTGE+RT R + ++   T  + V+VRDNG+PSLS++  + + + D   +
Sbjct: 613 STAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE 672

Query: 687 ILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACCGGFC 746
            +P +   +  P   S++TLYLI+AL+TVS + L+T   LS  KC +  A G    GG C
Sbjct: 673 EMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLS-AKCLQGNADGDG-GGGQC 730

Query: 747 GVRERSPA-ELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDT 805
             R+ SP+ + YKQ++ N+       LK    ++EV    + ++++CY+ C +  S    
Sbjct: 731 CRRQDSPSPDFYKQSSPNLQVSSDGTLK----YMEVTLRPTDSQSHCYRTCFSPASDGSD 786

Query: 806 FMF 808
           F F
Sbjct: 787 FTF 789


>gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precursor
           [Homo sapiens]
          Length = 944

 Score =  664 bits (1712), Expect = 0.0
 Identities = 355/783 (45%), Positives = 505/783 (64%), Gaps = 10/783 (1%)

Query: 28  LLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSP 87
           +L +L L   G  + QLRYSV EE  PG LVGNVA+ LGL++  L    L++      + 
Sbjct: 15  VLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLG--SEENG 72

Query: 88  RYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPR 147
           RY  L L SGAL VN++IDRE+LC     CLL ++V+  +P+ +  VEVEILD+NDNSP 
Sbjct: 73  RYFSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPS 132

Query: 148 FPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVL 207
           F  P  ++++SES A GARF ++SAQDPDVG N+V  Y LSP+ HF L++K L++     
Sbjct: 133 FATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFP 192

Query: 208 ELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLR 267
           ELVL + LDRE  A H LVLTAVDGG PARSGT  ISV VLD NDN+P F  S  RV + 
Sbjct: 193 ELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIP 252

Query: 268 EDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEE 327
           E++P GTL+++LNA+DPDEG+NG+L YS   +TS+  R LF +D S+G + V+G +D+EE
Sbjct: 253 ENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEE 312

Query: 328 ASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVL 387
           +  Y+I+ +A D+G   M GHC + VD+ DVNDNAPEV+L  L +PV E+    T+V + 
Sbjct: 313 SRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLF 372

Query: 388 SVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIP 447
           +V D+DSG N +VSL +   LPF++    N Y+L+ S PLDRE  + Y I + A+D G P
Sbjct: 373 NVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLTSQPLDREATSHYIIELLASDAGSP 432

Query: 448 QLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYS 507
            L    T+++ ISD+NDN P F +  Y+ YI EN  PG LLCTV A+DPD  +NA +TYS
Sbjct: 433 SLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYS 492

Query: 508 LLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANV 567
           ++  ++QG P +S+V +N   G ++A  +FDYE  +   + V  +D GSPPL +  + +V
Sbjct: 493 IVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHV 552

Query: 568 YVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH-LAQ 626
           +V+D ND+AP +L+P      +A + +PR+AP G LVTKV A+D+D+G NAWL Y  L Q
Sbjct: 553 FVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQ 612

Query: 627 TSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSK 686
           ++   LF V  HTGE+RT R + ++   T  + V+VRDNG+PSLS++  + + + D   +
Sbjct: 613 STAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPE 672

Query: 687 ILPDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACCGGFC 746
            +P +   +  P   S++TLYLI+AL+TVS + L+T   LS  KC +  A G    GG C
Sbjct: 673 EMPKSSDFLIHPPERSDLTLYLIVALATVSLLSLVTFTFLS-AKCLQGNADGDG-GGGQC 730

Query: 747 GVRERSPA-ELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDT 805
             R+ SP+ + YKQ++ N+       LK    ++EV    + ++++CY+ C +  S    
Sbjct: 731 CRRQDSPSPDFYKQSSPNLQVSSDGTLK----YMEVTLRPTDSQSHCYRTCFSPASDGSD 786

Query: 806 FMF 808
           F F
Sbjct: 787 FTF 789


>gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
          Length = 896

 Score =  654 bits (1688), Expect = 0.0
 Identities = 377/896 (42%), Positives = 538/896 (60%), Gaps = 80/896 (8%)

Query: 25  LLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGP-GCLRINHLG 83
           ++ LLL  LL +     SQL Y+V EEQ  G  VGN+A  LGL++ +L   G   + +  
Sbjct: 1   MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60

Query: 84  APSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDIND 143
            P   YL+L+L +G L+VNE+IDRE +C+Q P C+L LEV   NP+ +  VE+E+LDIND
Sbjct: 61  TP---YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDIND 117

Query: 144 NSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQEN 203
           N P FP P+  +++SES  PG RF +ESA DPDVG NS++ YE++P+ +F LD++   + 
Sbjct: 118 NPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDG 177

Query: 204 SKVLELVLRKGLDREQAALHHLVLTAVDGG----------------IPA---RSGTAQIS 244
           ++  ELVL K LDREQ A+H  VLTAVDGG                +P    R+GTA ++
Sbjct: 178 NRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLT 237

Query: 245 VRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRE 304
           +RVLD+NDN PAFDQ  Y V L E+SPPGTLV++LNA+DPDEG NGE+ YS SS+ S R 
Sbjct: 238 IRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRA 297

Query: 305 RQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPE 364
           R+LF +   TG + V G LDYEE+  YQ+YVQA D GP  +  HCKVLV ++D NDNAPE
Sbjct: 298 RELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPE 357

Query: 365 VVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVV 423
           +  + +   V E A P T+VA+ SV D+DS  N +V   L   +PFRL + F N YT+V 
Sbjct: 358 ISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVT 417

Query: 424 SGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNL 483
             PLDRE    Y +TV A D G P L++ ++++V++SD+NDN P F +  Y +Y+ ENN+
Sbjct: 418 EAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNV 477

Query: 484 PGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFR 543
           PG  +  V ATD DE  NA++ YS+LE +IQG+ V +YVSINS +G LYA+ SFDYE+ +
Sbjct: 478 PGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLK 537

Query: 544 EFFVTVEAQDKGSP-PLSSTVTANVYVVDMNDHAPHILYP-TSTNSSAAFEMVPRTAPAG 601
           +F   VEA+D GSP  L+   T N+ +VD ND+AP I+ P    N + A E++PR+A  G
Sbjct: 538 DFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPG 597

Query: 602 YLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKM--GDESGSTFNLT 659
           YL+T+V A+D+D G+NA L Y + + ++++LF+++  TGE+RT R++    +    + L 
Sbjct: 598 YLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELV 657

Query: 660 VVVRDNGEPSLSASVAITVAVVDRVSKILP------------DTQRHVKS--PRTYSEIT 705
           + VRD+G+P LS++  + V +VD    + P            + QR  +S    T  ++T
Sbjct: 658 IEVRDHGQPPLSSTATLVVQLVD--GAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLT 715

Query: 706 LYLIIALSTVSFIFLLTIIILSIIKCYR------YTAYGTACC--------GGFCGVRER 751
           L LIIAL +VSFIFLL +I+L+ ++C +      YT   + CC        GG      +
Sbjct: 716 LILIIALGSVSFIFLLAMIVLA-VRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQ 774

Query: 752 SPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSL-----TKTYCYKACLTAGSGSDTF 806
           + A   K + ++I       +   P  + +  +G        + YCY+ CLT  S     
Sbjct: 775 ARARKKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDL 834

Query: 807 MFY-----NTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEVR 857
           MF      +    T   P GA         +TG + Q      I+ N ++  NEVR
Sbjct: 835 MFLKPCSPSRSTDTEHNPCGA--------IVTGYTDQQPD---IISNGSILSNEVR 879


>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
          Length = 1040

 Score =  652 bits (1682), Expect = 0.0
 Identities = 376/892 (42%), Positives = 532/892 (59%), Gaps = 74/892 (8%)

Query: 25  LLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGP-GCLRINHLG 83
           ++ LLL  LL +     SQL Y+V EEQ  G  VGN+A  LGL++ +L   G   + +  
Sbjct: 1   MIVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSR 60

Query: 84  APSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDIND 143
            P   YL+L+L +G L+VNE+IDRE +C+Q P C+L LEV   NP+ +  VE+E+LDIND
Sbjct: 61  TP---YLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDIND 117

Query: 144 NSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQEN 203
           N P FP P+  +++SES  PG RF +ESA DPDVG NS++ YE++P+ +F LD++   + 
Sbjct: 118 NPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDG 177

Query: 204 SKVLELVLRKGLDREQAALHHLVLTAVDGG----------------IPA---RSGTAQIS 244
           ++  ELVL K LDREQ A+H  VLTAVDGG                +P    R+GTA ++
Sbjct: 178 NRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLT 237

Query: 245 VRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRE 304
           +RVLD+NDN PAFDQ  Y V L E+SPPGTLV++LNA+DPDEG NGE+ YS SS+ S R 
Sbjct: 238 IRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRA 297

Query: 305 RQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPE 364
           R+LF +   TG + V G LDYEE+  YQ+YVQA D GP  +  HCKVLV ++D NDNAPE
Sbjct: 298 RELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPE 357

Query: 365 VVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVV 423
           +  + +   V E A P T+VA+ SV D+DS  N +V   L   +PFRL + F N YT+V 
Sbjct: 358 ISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVT 417

Query: 424 SGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNL 483
             PLDRE    Y +TV A D G P L++ ++++V++SD+NDN P F +  Y +Y+ ENN+
Sbjct: 418 EAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNV 477

Query: 484 PGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFR 543
           PG  +  V ATD DE  NA++ YS+LE +IQG+ V +YVSINS +G LYA+ SFDYE+ +
Sbjct: 478 PGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLK 537

Query: 544 EFFVTVEAQDKGSP-PLSSTVTANVYVVDMNDHAPHILYP-TSTNSSAAFEMVPRTAPAG 601
           +F   VEA+D GSP  L+   T N+ +VD ND+AP I+ P    N + A E++PR+A  G
Sbjct: 538 DFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPG 597

Query: 602 YLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKM--GDESGSTFNLT 659
           YL+T+V A+D+D G+NA L Y + + ++++LF+++  TGE+RT R++    +    + L 
Sbjct: 598 YLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELV 657

Query: 660 VVVRDNGEPSLSASVAITVAVVDRVSKILP------------DTQRHVKS--PRTYSEIT 705
           + VRD+G+P LS++  + V +VD    + P            + QR  +S    T  ++T
Sbjct: 658 IEVRDHGQPPLSSTATLVVQLVD--GAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLT 715

Query: 706 LYLIIALSTVSFIFLLTIIILSIIKCYR------YTAYGTACC--------GGFCGVRER 751
           L LIIAL +VSFIFLL +I+L+ ++C +      YT   + CC        GG      +
Sbjct: 716 LILIIALGSVSFIFLLAMIVLA-VRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQ 774

Query: 752 SPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSL-----TKTYCYKACLTAGSGSDTF 806
           + A   K + ++I       +   P  + +  +G        + YCY+ CLT  S     
Sbjct: 775 ARARKKKLSKSDIMLVQSSNVPSNPAQVPIEESGGFGSHHHNQNYCYQVCLTPESAKTDL 834

Query: 807 MFY-----NTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQ 853
           MF      +    T   P GA          T Q      N  IL NE   Q
Sbjct: 835 MFLKPCSPSRSTDTEHNPCGAIVT-----GYTDQQPDIISNGSILSNETKHQ 881


>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  640 bits (1651), Expect = 0.0
 Identities = 368/800 (46%), Positives = 504/800 (63%), Gaps = 40/800 (5%)

Query: 15  RLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGP 74
           RL R    L+LL +LL  L        +Q+RYSVPEE   G+ VG+++R LGLE R L  
Sbjct: 5   RLHRDYKGLVLLGILLGTLW---ETGCTQIRYSVPEELEKGSRVGDISRDLGLEPRELAE 61

Query: 75  GCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAV 134
             +RI   G    +   L+  SG+L    RIDRE LC    +C L+L++L  + V +  V
Sbjct: 62  RGVRIIPRGRT--QLFALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGV 119

Query: 135 EVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFE 194
           EVE+ DINDN+P F     ++++SE+ A   RF +  A DPD+G NS+Q+YELSP+ HF 
Sbjct: 120 EVEVRDINDNAPYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFS 179

Query: 195 LDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNS 254
           L ++   + SK  ELVL++ LDRE+ A HHLVLTA DGG P R+GTA+I V VLD NDN+
Sbjct: 180 LIVQNGADGSKYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNA 239

Query: 255 PAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDAST 314
           PAF Q  YR  + E+   GT ++ +NA+DPDEG N E+RYS   Y  D+  Q+F +D ++
Sbjct: 240 PAFAQPEYRASVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNS 298

Query: 315 GEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPV 374
           G +  IG LD+EE+  YQ+ VQA D      +   KVL+ ++DVNDNAPEVVLT L S V
Sbjct: 299 GTISTIGELDHEESGFYQMEVQAMDN--AGYSARAKVLITVLDVNDNAPEVVLTSLASSV 356

Query: 375 PENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVA 433
           PEN+   T++A+L+VNDQDS  N +V   ++  LPF+L   +GN Y+LV    LDRE+V 
Sbjct: 357 PENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVP 416

Query: 434 VYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQA 493
            YNITVTATD G P L++   + + ++D NDNPP F + SYS YI ENN  GV L +V A
Sbjct: 417 SYNITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTA 476

Query: 494 TDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQD 553
            DPD +ENA++TYSL E  IQG  ++SYVSINS +G LYA++SFDYE+FR+  V V A+D
Sbjct: 477 HDPDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARD 536

Query: 554 KGSPPLSSTVTANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDS 612
            G PPLSS V+ +++V+D ND+AP ILYP   T+ S   E+ PR+A  GYLVTKV+A+D 
Sbjct: 537 NGHPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDR 596

Query: 613 DSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSA 672
           DSGQNAWL Y L + S+  LF V LHTGE+RT R + D      +L V V+D+G+P LSA
Sbjct: 597 DSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSA 656

Query: 673 SVAITVAVVDRVSKILPDTQRHVKSPRT--YSEITLYLIIALSTVSFIFLLTIIILSIIK 730
           +V +TVAV D + ++L D    ++SP     S++TLYL++A++ VS +FL  +I+L  ++
Sbjct: 657 TVTLTVAVADSIPQVLADL-GSLESPANSETSDLTLYLVVAVAAVSCVFLAFVILLLALR 715

Query: 731 CYRY--TAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLT 788
             R+  +    A  GG  G    +PA                      HF+ V G  +  
Sbjct: 716 LRRWHKSRLLQASGGGLTG----APAS---------------------HFVGVDGVQAFL 750

Query: 789 KTYCYKACLTAGSGSDTFMF 808
           +TY ++  LT  S     +F
Sbjct: 751 QTYSHEVSLTTDSRKSHLIF 770


>gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precursor
           [Homo sapiens]
          Length = 820

 Score =  640 bits (1651), Expect = 0.0
 Identities = 368/800 (46%), Positives = 504/800 (63%), Gaps = 40/800 (5%)

Query: 15  RLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGP 74
           RL R    L+LL +LL  L        +Q+RYSVPEE   G+ VG+++R LGLE R L  
Sbjct: 5   RLHRDYKGLVLLGILLGTLW---ETGCTQIRYSVPEELEKGSRVGDISRDLGLEPRELAE 61

Query: 75  GCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAV 134
             +RI   G    +   L+  SG+L    RIDRE LC    +C L+L++L  + V +  V
Sbjct: 62  RGVRIIPRGRT--QLFALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGV 119

Query: 135 EVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFE 194
           EVE+ DINDN+P F     ++++SE+ A   RF +  A DPD+G NS+Q+YELSP+ HF 
Sbjct: 120 EVEVRDINDNAPYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFS 179

Query: 195 LDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNS 254
           L ++   + SK  ELVL++ LDRE+ A HHLVLTA DGG P R+GTA+I V VLD NDN+
Sbjct: 180 LIVQNGADGSKYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNA 239

Query: 255 PAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDAST 314
           PAF Q  YR  + E+   GT ++ +NA+DPDEG N E+RYS   Y  D+  Q+F +D ++
Sbjct: 240 PAFAQPEYRASVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNS 298

Query: 315 GEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPV 374
           G +  IG LD+EE+  YQ+ VQA D      +   KVL+ ++DVNDNAPEVVLT L S V
Sbjct: 299 GTISTIGELDHEESGFYQMEVQAMDN--AGYSARAKVLITVLDVNDNAPEVVLTSLASSV 356

Query: 375 PENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVA 433
           PEN+   T++A+L+VNDQDS  N +V   ++  LPF+L   +GN Y+LV    LDRE+V 
Sbjct: 357 PENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVP 416

Query: 434 VYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQA 493
            YNITVTATD G P L++   + + ++D NDNPP F + SYS YI ENN  GV L +V A
Sbjct: 417 SYNITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTA 476

Query: 494 TDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQD 553
            DPD +ENA++TYSL E  IQG  ++SYVSINS +G LYA++SFDYE+FR+  V V A+D
Sbjct: 477 HDPDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARD 536

Query: 554 KGSPPLSSTVTANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDS 612
            G PPLSS V+ +++V+D ND+AP ILYP   T+ S   E+ PR+A  GYLVTKV+A+D 
Sbjct: 537 NGHPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDR 596

Query: 613 DSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSA 672
           DSGQNAWL Y L + S+  LF V LHTGE+RT R + D      +L V V+D+G+P LSA
Sbjct: 597 DSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSA 656

Query: 673 SVAITVAVVDRVSKILPDTQRHVKSPRT--YSEITLYLIIALSTVSFIFLLTIIILSIIK 730
           +V +TVAV D + ++L D    ++SP     S++TLYL++A++ VS +FL  +I+L  ++
Sbjct: 657 TVTLTVAVADSIPQVLADL-GSLESPANSETSDLTLYLVVAVAAVSCVFLAFVILLLALR 715

Query: 731 CYRY--TAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLT 788
             R+  +    A  GG  G    +PA                      HF+ V G  +  
Sbjct: 716 LRRWHKSRLLQASGGGLTG----APAS---------------------HFVGVDGVQAFL 750

Query: 789 KTYCYKACLTAGSGSDTFMF 808
           +TY ++  LT  S     +F
Sbjct: 751 QTYSHEVSLTTDSRKSHLIF 770


>gi|14270484 protocadherin gamma subfamily A, 8 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  629 bits (1622), Expect = e-180
 Identities = 333/712 (46%), Positives = 468/712 (65%), Gaps = 8/712 (1%)

Query: 26  LPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAP 85
           L LL  LL  L      Q+RYSVPEE   G+ VGN+++ LGL+ R+L    +RI   G  
Sbjct: 13  LILLCALLGTLWEIGRGQIRYSVPEETDKGSFVGNISKDLGLDPRKLAKHGVRIVSRGRT 72

Query: 86  SPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNS 145
             +   L+  SG+L    RIDRE LC Q PRCL+++  L  +   +  VE+EI+DINDN+
Sbjct: 73  --QLFALNPRSGSLITAGRIDREELCAQSPRCLININTLVEDKGKLFGVEIEIIDINDNN 130

Query: 146 PRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSK 205
           P+F   + +++++E   PGAR+ +  A DPDVG NS+Q+Y+LSP+ HF LD++     + 
Sbjct: 131 PKFQVEDLEVKINEIAVPGARYPLPEAVDPDVGVNSLQSYQLSPNHHFSLDVQTGDNGAI 190

Query: 206 VLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQ 265
             ELVL + LDRE+ A HHLVLTA DGG P RS T +I V VLDTNDN+P F    YRV+
Sbjct: 191 NPELVLERALDREEEAAHHLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVFPHPIYRVK 250

Query: 266 LREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDY 325
           + E+ PPGT ++ + ASDPDEG NG++ Y      ++++  LF ++ +TGE+ +   LDY
Sbjct: 251 VLENMPPGTRLLTVTASDPDEGINGKVAYKFRK-INEKQTPLFQLNENTGEISIAKSLDY 309

Query: 326 EEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVA 385
           EE S Y++ +QA D G   + G  K+L+ + DVNDN PEV++T L+SPV EN+ P T++A
Sbjct: 310 EECSFYEMEIQAEDVG--ALLGRTKLLISVEDVNDNRPEVIITSLFSPVLENSLPGTVIA 367

Query: 386 VLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDG 444
            LSV+DQDSG N +V       LPF+L    GN Y LV    LDRE V++YNITV A+D 
Sbjct: 368 FLSVHDQDSGKNGQVVCYTRDNLPFKLEKSIGNYYRLVTRKYLDRENVSIYNITVMASDL 427

Query: 445 GIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEV 504
           G P L++   + + ++DINDNPP+F   SYS YI ENNL G  + ++ A DPD +ENA+V
Sbjct: 428 GTPPLSTETQIALHVADINDNPPTFPHASYSAYILENNLRGASIFSLTAHDPDSQENAQV 487

Query: 505 TYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVT 564
           TYS+ E  +QG P++SY+SINS +G LYA+ SFDYE+ R+  + V A D G PPLSS ++
Sbjct: 488 TYSVTEDTLQGAPLSSYISINSDTGVLYALQSFDYEQIRDLQLLVTASDSGDPPLSSNMS 547

Query: 565 ANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH 623
            +++V+D ND+AP ILYP   T+ S   E+ PR+A  GYLVTKV+A+D DSGQNAWL Y 
Sbjct: 548 LSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAERGYLVTKVVAVDRDSGQNAWLSYR 607

Query: 624 LAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDR 683
           L + S+  LF V LHTGE+RT R + D      +L V V+D+G+P LSA+V +TVAV D 
Sbjct: 608 LLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADS 667

Query: 684 VSKILPDTQRHVKS-PRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRY 734
           + ++L +      S     S +TLYL++A++ +S +FL  + +L  ++  R+
Sbjct: 668 IPEVLTELGSLKPSVDPNDSSLTLYLVVAVAAISCVFLAFVAVLLGLRLRRW 719


>gi|7662056 protocadherin gamma subfamily A, 8 isoform 2 precursor
           [Homo sapiens]
          Length = 820

 Score =  629 bits (1622), Expect = e-180
 Identities = 333/712 (46%), Positives = 468/712 (65%), Gaps = 8/712 (1%)

Query: 26  LPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAP 85
           L LL  LL  L      Q+RYSVPEE   G+ VGN+++ LGL+ R+L    +RI   G  
Sbjct: 13  LILLCALLGTLWEIGRGQIRYSVPEETDKGSFVGNISKDLGLDPRKLAKHGVRIVSRGRT 72

Query: 86  SPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNS 145
             +   L+  SG+L    RIDRE LC Q PRCL+++  L  +   +  VE+EI+DINDN+
Sbjct: 73  --QLFALNPRSGSLITAGRIDREELCAQSPRCLININTLVEDKGKLFGVEIEIIDINDNN 130

Query: 146 PRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSK 205
           P+F   + +++++E   PGAR+ +  A DPDVG NS+Q+Y+LSP+ HF LD++     + 
Sbjct: 131 PKFQVEDLEVKINEIAVPGARYPLPEAVDPDVGVNSLQSYQLSPNHHFSLDVQTGDNGAI 190

Query: 206 VLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQ 265
             ELVL + LDRE+ A HHLVLTA DGG P RS T +I V VLDTNDN+P F    YRV+
Sbjct: 191 NPELVLERALDREEEAAHHLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVFPHPIYRVK 250

Query: 266 LREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDY 325
           + E+ PPGT ++ + ASDPDEG NG++ Y      ++++  LF ++ +TGE+ +   LDY
Sbjct: 251 VLENMPPGTRLLTVTASDPDEGINGKVAYKFRK-INEKQTPLFQLNENTGEISIAKSLDY 309

Query: 326 EEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVA 385
           EE S Y++ +QA D G   + G  K+L+ + DVNDN PEV++T L+SPV EN+ P T++A
Sbjct: 310 EECSFYEMEIQAEDVG--ALLGRTKLLISVEDVNDNRPEVIITSLFSPVLENSLPGTVIA 367

Query: 386 VLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDG 444
            LSV+DQDSG N +V       LPF+L    GN Y LV    LDRE V++YNITV A+D 
Sbjct: 368 FLSVHDQDSGKNGQVVCYTRDNLPFKLEKSIGNYYRLVTRKYLDRENVSIYNITVMASDL 427

Query: 445 GIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEV 504
           G P L++   + + ++DINDNPP+F   SYS YI ENNL G  + ++ A DPD +ENA+V
Sbjct: 428 GTPPLSTETQIALHVADINDNPPTFPHASYSAYILENNLRGASIFSLTAHDPDSQENAQV 487

Query: 505 TYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVT 564
           TYS+ E  +QG P++SY+SINS +G LYA+ SFDYE+ R+  + V A D G PPLSS ++
Sbjct: 488 TYSVTEDTLQGAPLSSYISINSDTGVLYALQSFDYEQIRDLQLLVTASDSGDPPLSSNMS 547

Query: 565 ANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH 623
            +++V+D ND+AP ILYP   T+ S   E+ PR+A  GYLVTKV+A+D DSGQNAWL Y 
Sbjct: 548 LSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAERGYLVTKVVAVDRDSGQNAWLSYR 607

Query: 624 LAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDR 683
           L + S+  LF V LHTGE+RT R + D      +L V V+D+G+P LSA+V +TVAV D 
Sbjct: 608 LLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADS 667

Query: 684 VSKILPDTQRHVKS-PRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRY 734
           + ++L +      S     S +TLYL++A++ +S +FL  + +L  ++  R+
Sbjct: 668 IPEVLTELGSLKPSVDPNDSSLTLYLVVAVAAISCVFLAFVAVLLGLRLRRW 719


>gi|14196468 protocadherin gamma subfamily A, 4 isoform 2 precursor
           [Homo sapiens]
          Length = 820

 Score =  622 bits (1604), Expect = e-178
 Identities = 352/804 (43%), Positives = 498/804 (61%), Gaps = 41/804 (5%)

Query: 8   PAATEHPRLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGL 67
           PA  +H RL +          + LLL +L    A Q+ YSV EEQ  G++VGN+A+ LGL
Sbjct: 5   PARPDHTRLLQ----------ICLLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGL 54

Query: 68  ELRRLGPGCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHN 127
             R L    +RI   G    +   L+  SG L    RIDRE LC++ P C+ +LE+L  +
Sbjct: 55  APRELAERGVRIVSRGRT--QLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLED 112

Query: 128 PVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYEL 187
            V +  VEVEI+D+NDN P F     +++V+E+  PGARF +  A DPDVG NS+Q Y+L
Sbjct: 113 TVKILRVEVEIIDVNDNPPSFGTEQREIKVAENENPGARFPLPEAFDPDVGVNSLQGYQL 172

Query: 188 SPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRV 247
           + + +F LD++   +  K  ELVL + LDRE+ A+HHLVLTA DGG P RSGTA+I + +
Sbjct: 173 NSNGYFSLDVQSGADGIKYPELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIIL 232

Query: 248 LDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQL 307
           +DTNDN+P F Q  Y V +RE+ P GT ++ + A+DPDEG+NG++ YS      D+  QL
Sbjct: 233 VDTNDNAPVFTQPEYHVSVRENVPVGTRLLTVKATDPDEGANGDVTYSFRK-VRDKISQL 291

Query: 308 FSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVL 367
           F +++ +G++ ++GGLDYE++  Y I V+A D GP  +    KVLV ++D NDNAPEV +
Sbjct: 292 FQLNSLSGDITILGGLDYEDSGFYDIDVEAHD-GP-GLRARSKVLVTVLDENDNAPEVTV 349

Query: 368 TDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGP 426
           T L S V E+++P T++A+ +V+D DSG N  V+  +   LPF L   +GN Y L+    
Sbjct: 350 TSLTSSVQESSSPGTVIALFNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRT 409

Query: 427 LDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGV 486
           LDRE V+ YNITVTATD G P L++   + +++ DINDNPP+F   SYS YI ENN  G 
Sbjct: 410 LDREEVSEYNITVTATDQGTPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGA 469

Query: 487 LLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFF 546
            + ++ A DPD  +NA +TYSL E   QG P++SYVSINS +G LYA+ SFDYE+FR+  
Sbjct: 470 SILSMTAQDPDSGDNARITYSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQ 529

Query: 547 VTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVT 605
           + + A D G PPLSS V+ +++V+D ND+ P ILYPT  T+ S   E+ PR+A +GYLVT
Sbjct: 530 LLMTASDSGDPPLSSNVSLSLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVT 589

Query: 606 KVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDN 665
           KV+A+D DSGQNAWL Y L ++S+  LF V LHTGE+RT R + D       L VVV+D+
Sbjct: 590 KVVAVDRDSGQNAWLSYSLLKSSEPGLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDH 649

Query: 666 GEPSLSASVAITVAVVDRVSKILPDT-QRHVKSPRTYSEITLYLIIALSTVSFIFLLTII 724
           G+P LSA+V +TVAV D +  +L D       +    S +TLYL++A++ VS +FL  + 
Sbjct: 650 GQPPLSATVTLTVAVADSIPDVLADLGSLKPSADPDDSGLTLYLVVAVAAVSCVFLAFVT 709

Query: 725 ILSIIKCYRYTAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGN 784
           +L  +K  R+                   + L     + + A +P       HF+ V G 
Sbjct: 710 VLLALKLRRW-----------------HKSRLLHAEGSRL-AGVP-----ASHFVGVDGV 746

Query: 785 GSLTKTYCYKACLTAGSGSDTFMF 808
            +  +TY ++  LTA S     +F
Sbjct: 747 RAFLQTYSHEVSLTADSRKSHLIF 770


>gi|11056026 protocadherin gamma subfamily A, 4 isoform 1 precursor
           [Homo sapiens]
          Length = 931

 Score =  622 bits (1604), Expect = e-178
 Identities = 352/804 (43%), Positives = 498/804 (61%), Gaps = 41/804 (5%)

Query: 8   PAATEHPRLRRPMPWLLLLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGL 67
           PA  +H RL +          + LLL +L    A Q+ YSV EEQ  G++VGN+A+ LGL
Sbjct: 5   PARPDHTRLLQ----------ICLLLGVLVEIRAEQILYSVFEEQEEGSVVGNIAKDLGL 54

Query: 68  ELRRLGPGCLRINHLGAPSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHN 127
             R L    +RI   G    +   L+  SG L    RIDRE LC++ P C+ +LE+L  +
Sbjct: 55  APRELAERGVRIVSRGRT--QLFALNPRSGTLVTAGRIDREELCDRSPNCVTNLEILLED 112

Query: 128 PVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYEL 187
            V +  VEVEI+D+NDN P F     +++V+E+  PGARF +  A DPDVG NS+Q Y+L
Sbjct: 113 TVKILRVEVEIIDVNDNPPSFGTEQREIKVAENENPGARFPLPEAFDPDVGVNSLQGYQL 172

Query: 188 SPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRV 247
           + + +F LD++   +  K  ELVL + LDRE+ A+HHLVLTA DGG P RSGTA+I + +
Sbjct: 173 NSNGYFSLDVQSGADGIKYPELVLERALDREEEAVHHLVLTAFDGGDPVRSGTARILIIL 232

Query: 248 LDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQL 307
           +DTNDN+P F Q  Y V +RE+ P GT ++ + A+DPDEG+NG++ YS      D+  QL
Sbjct: 233 VDTNDNAPVFTQPEYHVSVRENVPVGTRLLTVKATDPDEGANGDVTYSFRK-VRDKISQL 291

Query: 308 FSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVL 367
           F +++ +G++ ++GGLDYE++  Y I V+A D GP  +    KVLV ++D NDNAPEV +
Sbjct: 292 FQLNSLSGDITILGGLDYEDSGFYDIDVEAHD-GP-GLRARSKVLVTVLDENDNAPEVTV 349

Query: 368 TDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGP 426
           T L S V E+++P T++A+ +V+D DSG N  V+  +   LPF L   +GN Y L+    
Sbjct: 350 TSLTSSVQESSSPGTVIALFNVHDSDSGGNGLVTCSIPDNLPFTLEKTYGNYYRLLTHRT 409

Query: 427 LDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGV 486
           LDRE V+ YNITVTATD G P L++   + +++ DINDNPP+F   SYS YI ENN  G 
Sbjct: 410 LDREEVSEYNITVTATDQGTPPLSTETHISLQVMDINDNPPTFPHASYSAYIPENNPRGA 469

Query: 487 LLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFF 546
            + ++ A DPD  +NA +TYSL E   QG P++SYVSINS +G LYA+ SFDYE+FR+  
Sbjct: 470 SILSMTAQDPDSGDNARITYSLAEDTFQGAPLSSYVSINSNTGILYALCSFDYEQFRDLQ 529

Query: 547 VTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVT 605
           + + A D G PPLSS V+ +++V+D ND+ P ILYPT  T+ S   E+ PR+A +GYLVT
Sbjct: 530 LLMTASDSGDPPLSSNVSLSLFVLDQNDNVPEILYPTFPTDGSTGVELAPRSADSGYLVT 589

Query: 606 KVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDN 665
           KV+A+D DSGQNAWL Y L ++S+  LF V LHTGE+RT R + D       L VVV+D+
Sbjct: 590 KVVAVDRDSGQNAWLSYSLLKSSEPGLFAVGLHTGEVRTARALLDRDALKQRLVVVVQDH 649

Query: 666 GEPSLSASVAITVAVVDRVSKILPDT-QRHVKSPRTYSEITLYLIIALSTVSFIFLLTII 724
           G+P LSA+V +TVAV D +  +L D       +    S +TLYL++A++ VS +FL  + 
Sbjct: 650 GQPPLSATVTLTVAVADSIPDVLADLGSLKPSADPDDSGLTLYLVVAVAAVSCVFLAFVT 709

Query: 725 ILSIIKCYRYTAYGTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGN 784
           +L  +K  R+                   + L     + + A +P       HF+ V G 
Sbjct: 710 VLLALKLRRW-----------------HKSRLLHAEGSRL-AGVP-----ASHFVGVDGV 746

Query: 785 GSLTKTYCYKACLTAGSGSDTFMF 808
            +  +TY ++  LTA S     +F
Sbjct: 747 RAFLQTYSHEVSLTADSRKSHLIF 770


>gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precursor
           [Homo sapiens]
          Length = 837

 Score =  620 bits (1598), Expect = e-177
 Identities = 350/790 (44%), Positives = 493/790 (62%), Gaps = 37/790 (4%)

Query: 25  LLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGA 84
           LL LL + L  L G  A Q+RYSVPEE   G+ VGN+++ LGLE R L    +RI   G 
Sbjct: 13  LLLLLCIFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRG- 71

Query: 85  PSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDN 144
              +   ++  SG+L    RIDRE LCE    C L++E+L  + + +  VEVEI+DINDN
Sbjct: 72  -KTQLFAVNPRSGSLITAGRIDREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDN 130

Query: 145 SPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENS 204
           +P F     +++VSE   PGARF + +A+DPDVG NS+Q+Y+LSP+ +F L L+   + +
Sbjct: 131 APSFQEDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGA 190

Query: 205 KVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRV 264
           K  ELVL   LDRE+ A H L+LTA+DGG P R G   I V VLD ND+ P F QS YRV
Sbjct: 191 KNPELVLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRV 250

Query: 265 QLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLD 324
            + E+   GT V+ +NA+DPDEG NGE+ YS  +  S +  ++F +D+ TGEV+V G LD
Sbjct: 251 SVPENISSGTRVLMVNATDPDEGINGEVMYSFRNMES-KASEIFQLDSQTGEVQVRGSLD 309

Query: 325 YEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIV 384
           +E+   Y++ +Q  D G   +     +L+ +VDVNDNAPE+ +T   + + EN+ P T++
Sbjct: 310 FEKYRFYEMEIQGQDGG--GLFTTTTMLITVVDVNDNAPEITITSSINSILENSPPGTVI 367

Query: 385 AVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATD 443
           A+L+V DQDSG N +VS  +   LPF+L   +GN Y L+ S  LDRE V  YNIT+TATD
Sbjct: 368 ALLNVQDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATD 427

Query: 444 GGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAE 503
            G P L++   + + ++D NDNPP F   SYS YI ENN  G  + +V A DPD K+NA 
Sbjct: 428 QGSPPLSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNAL 487

Query: 504 VTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTV 563
           VTYSL +  +QG+P++SYVSINS +G LYA+ SFDYE+FR+  + V A+D G PPLSS V
Sbjct: 488 VTYSLTDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSGDPPLSSNV 547

Query: 564 TANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFY 622
           + +++V+D ND+AP ILYP   T+ S   E+ PR+A  GYLVTKV+A+D DSGQNAWL Y
Sbjct: 548 SLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSY 607

Query: 623 HLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVD 682
            L + S+  LF V  HTGE+RT R + D      +L V V+D+G+P LSA+V +TVAV D
Sbjct: 608 RLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 667

Query: 683 RVSKILPD--TQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRY--TAYG 738
            + ++L D  +   + +  T S+++LYL++A++ VS IFL+ +I+L  ++ +R+  +   
Sbjct: 668 SIPEVLADLGSLESLANSET-SDLSLYLVVAVAAVSCIFLVFVIVLLALRLWRWHKSRLL 726

Query: 739 TACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLT 798
            A  GG  G+                            HF+ V G  +  +TY ++  L 
Sbjct: 727 QASEGGLAGM-------------------------PTSHFVGVDGVQAFLQTYSHEVSLI 761

Query: 799 AGSGSDTFMF 808
           A S     +F
Sbjct: 762 ADSQKSHLIF 771


>gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precursor
           [Homo sapiens]
          Length = 935

 Score =  620 bits (1598), Expect = e-177
 Identities = 350/790 (44%), Positives = 493/790 (62%), Gaps = 37/790 (4%)

Query: 25  LLPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGA 84
           LL LL + L  L G  A Q+RYSVPEE   G+ VGN+++ LGLE R L    +RI   G 
Sbjct: 13  LLLLLCIFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRG- 71

Query: 85  PSPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDN 144
              +   ++  SG+L    RIDRE LCE    C L++E+L  + + +  VEVEI+DINDN
Sbjct: 72  -KTQLFAVNPRSGSLITAGRIDREELCETVSSCFLNMELLVEDTLKIYGVEVEIIDINDN 130

Query: 145 SPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENS 204
           +P F     +++VSE   PGARF + +A+DPDVG NS+Q+Y+LSP+ +F L L+   + +
Sbjct: 131 APSFQEDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGA 190

Query: 205 KVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRV 264
           K  ELVL   LDRE+ A H L+LTA+DGG P R G   I V VLD ND+ P F QS YRV
Sbjct: 191 KNPELVLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRV 250

Query: 265 QLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLD 324
            + E+   GT V+ +NA+DPDEG NGE+ YS  +  S +  ++F +D+ TGEV+V G LD
Sbjct: 251 SVPENISSGTRVLMVNATDPDEGINGEVMYSFRNMES-KASEIFQLDSQTGEVQVRGSLD 309

Query: 325 YEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIV 384
           +E+   Y++ +Q  D G   +     +L+ +VDVNDNAPE+ +T   + + EN+ P T++
Sbjct: 310 FEKYRFYEMEIQGQDGG--GLFTTTTMLITVVDVNDNAPEITITSSINSILENSPPGTVI 367

Query: 385 AVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATD 443
           A+L+V DQDSG N +VS  +   LPF+L   +GN Y L+ S  LDRE V  YNIT+TATD
Sbjct: 368 ALLNVQDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATD 427

Query: 444 GGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAE 503
            G P L++   + + ++D NDNPP F   SYS YI ENN  G  + +V A DPD K+NA 
Sbjct: 428 QGSPPLSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALDPDSKQNAL 487

Query: 504 VTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTV 563
           VTYSL +  +QG+P++SYVSINS +G LYA+ SFDYE+FR+  + V A+D G PPLSS V
Sbjct: 488 VTYSLTDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSGDPPLSSNV 547

Query: 564 TANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFY 622
           + +++V+D ND+AP ILYP   T+ S   E+ PR+A  GYLVTKV+A+D DSGQNAWL Y
Sbjct: 548 SLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNAWLSY 607

Query: 623 HLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVD 682
            L + S+  LF V  HTGE+RT R + D      +L V V+D+G+P LSA+V +TVAV D
Sbjct: 608 RLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 667

Query: 683 RVSKILPD--TQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRY--TAYG 738
            + ++L D  +   + +  T S+++LYL++A++ VS IFL+ +I+L  ++ +R+  +   
Sbjct: 668 SIPEVLADLGSLESLANSET-SDLSLYLVVAVAAVSCIFLVFVIVLLALRLWRWHKSRLL 726

Query: 739 TACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLT 798
            A  GG  G+                            HF+ V G  +  +TY ++  L 
Sbjct: 727 QASEGGLAGM-------------------------PTSHFVGVDGVQAFLQTYSHEVSLI 761

Query: 799 AGSGSDTFMF 808
           A S     +F
Sbjct: 762 ADSQKSHLIF 771


>gi|11056065 protocadherin gamma subfamily A, 6 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  618 bits (1593), Expect = e-177
 Identities = 358/834 (42%), Positives = 504/834 (60%), Gaps = 45/834 (5%)

Query: 28  LLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSP 87
           LLL LL  L G AA+Q+RYS+PEE   G+ VGN+ + LGLE + L    +RI   G    
Sbjct: 15  LLLTLLGTLWGAAAAQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGRM-- 72

Query: 88  RYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPR 147
           +   L+  +G+L    RIDRE LC Q PRCL+S  +L  + + +  VEVEI+DINDN+PR
Sbjct: 73  QLFSLNPRNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTPR 132

Query: 148 FPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVL 207
           F +   ++++ E+ AP +RF +    DPDVG NS+Q ++LS + HF +D++      K  
Sbjct: 133 FLKEELEVKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKYP 192

Query: 208 ELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLR 267
           ELVL   LDRE  A++ LVLTA+DGG P RS  AQI V VLD NDN+P F Q  YRV + 
Sbjct: 193 ELVLEGTLDREGEAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMFTQPVYRVSVP 252

Query: 268 EDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEE 327
           E+ P GT V+ + A+D DEG +GE+ YS    T ++  Q+F ++  TGE+     LDYE+
Sbjct: 253 ENLPVGTPVLAVTATDQDEGVHGEVTYSFVKIT-EKISQIFCLNVLTGEISTSANLDYED 311

Query: 328 ASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVL 387
           +S Y++ V+A D GP  +    KVL+ I+DVNDN PEVV+T     + E+A P T++A+ 
Sbjct: 312 SSFYELGVEARD-GP-GLRDRAKVLITILDVNDNVPEVVVTSGSRTIAESAPPGTVIALF 369

Query: 388 SVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGI 446
            V D+DSG N  V+  +  +LPF L    GN Y LV +  LDRE V +YNITVTATD G 
Sbjct: 370 QVFDRDSGLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAALDREEVFLYNITVTATDKGT 429

Query: 447 PQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTY 506
           P L++   + + ++D NDNPP+F   SYS+Y+ ENN  G  + +V A DPD  +NA+V+Y
Sbjct: 430 PPLSTETIISLNVADTNDNPPTFPHSSYSVYVLENNPRGASIFSVNALDPDVDQNAQVSY 489

Query: 507 SLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTAN 566
           SL E  +QG P++SYVSINS +G LYA+ SFDYE+ R+  + V A D G PPLSS V+ +
Sbjct: 490 SLAEDTLQGAPLSSYVSINSDTGILYALRSFDYEQLRDLQLWVTASDSGDPPLSSNVSLS 549

Query: 567 VYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLA 625
           ++V+D ND+AP ILYP   T+ S   E+ PR+A  GYLVTKV+A+D DSGQNAWL Y L 
Sbjct: 550 LFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLL 609

Query: 626 QTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVS 685
           + S+  LF V LHTGE+RT R + D      +L V V+D+G+P LSA+V +TVAV DR+ 
Sbjct: 610 KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIP 669

Query: 686 KILPDTQRHVKSPR-TYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACCGG 744
            IL D      S +   S++TLYL++A++ VS +FL  +I+L  ++  R+          
Sbjct: 670 DILADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLQRW---------- 719

Query: 745 FCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSD 804
                         QA+    A +P       HF+ V G  +  +TY ++  LTA S   
Sbjct: 720 --------HKSRLLQASGGGLASMPGS-----HFVGVEGVRAFLQTYSHEVSLTADSRKS 766

Query: 805 TFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEVRQ 858
             +F        P P+ A   +        +S + +  L+I ++   ++ E RQ
Sbjct: 767 HLIF--------PQPNYADTLINQ------ESYEKSEPLLITQDLLETKGEPRQ 806


>gi|14196474 protocadherin gamma subfamily A, 6 isoform 2 precursor
           [Homo sapiens]
          Length = 818

 Score =  618 bits (1593), Expect = e-177
 Identities = 358/834 (42%), Positives = 504/834 (60%), Gaps = 45/834 (5%)

Query: 28  LLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSP 87
           LLL LL  L G AA+Q+RYS+PEE   G+ VGN+ + LGLE + L    +RI   G    
Sbjct: 15  LLLTLLGTLWGAAAAQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGRM-- 72

Query: 88  RYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPR 147
           +   L+  +G+L    RIDRE LC Q PRCL+S  +L  + + +  VEVEI+DINDN+PR
Sbjct: 73  QLFSLNPRNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTPR 132

Query: 148 FPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVL 207
           F +   ++++ E+ AP +RF +    DPDVG NS+Q ++LS + HF +D++      K  
Sbjct: 133 FLKEELEVKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKYP 192

Query: 208 ELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLR 267
           ELVL   LDRE  A++ LVLTA+DGG P RS  AQI V VLD NDN+P F Q  YRV + 
Sbjct: 193 ELVLEGTLDREGEAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMFTQPVYRVSVP 252

Query: 268 EDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEE 327
           E+ P GT V+ + A+D DEG +GE+ YS    T ++  Q+F ++  TGE+     LDYE+
Sbjct: 253 ENLPVGTPVLAVTATDQDEGVHGEVTYSFVKIT-EKISQIFCLNVLTGEISTSANLDYED 311

Query: 328 ASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVL 387
           +S Y++ V+A D GP  +    KVL+ I+DVNDN PEVV+T     + E+A P T++A+ 
Sbjct: 312 SSFYELGVEARD-GP-GLRDRAKVLITILDVNDNVPEVVVTSGSRTIAESAPPGTVIALF 369

Query: 388 SVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGI 446
            V D+DSG N  V+  +  +LPF L    GN Y LV +  LDRE V +YNITVTATD G 
Sbjct: 370 QVFDRDSGLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAALDREEVFLYNITVTATDKGT 429

Query: 447 PQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTY 506
           P L++   + + ++D NDNPP+F   SYS+Y+ ENN  G  + +V A DPD  +NA+V+Y
Sbjct: 430 PPLSTETIISLNVADTNDNPPTFPHSSYSVYVLENNPRGASIFSVNALDPDVDQNAQVSY 489

Query: 507 SLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTAN 566
           SL E  +QG P++SYVSINS +G LYA+ SFDYE+ R+  + V A D G PPLSS V+ +
Sbjct: 490 SLAEDTLQGAPLSSYVSINSDTGILYALRSFDYEQLRDLQLWVTASDSGDPPLSSNVSLS 549

Query: 567 VYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLA 625
           ++V+D ND+AP ILYP   T+ S   E+ PR+A  GYLVTKV+A+D DSGQNAWL Y L 
Sbjct: 550 LFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLL 609

Query: 626 QTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVS 685
           + S+  LF V LHTGE+RT R + D      +L V V+D+G+P LSA+V +TVAV DR+ 
Sbjct: 610 KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIP 669

Query: 686 KILPDTQRHVKSPR-TYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACCGG 744
            IL D      S +   S++TLYL++A++ VS +FL  +I+L  ++  R+          
Sbjct: 670 DILADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLQRW---------- 719

Query: 745 FCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSD 804
                         QA+    A +P       HF+ V G  +  +TY ++  LTA S   
Sbjct: 720 --------HKSRLLQASGGGLASMPGS-----HFVGVEGVRAFLQTYSHEVSLTADSRKS 766

Query: 805 TFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEVRQ 858
             +F        P P+ A   +        +S + +  L+I ++   ++ E RQ
Sbjct: 767 HLIF--------PQPNYADTLINQ------ESYEKSEPLLITQDLLETKGEPRQ 806


>gi|11128043 protocadherin gamma subfamily A, 9 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  617 bits (1592), Expect = e-176
 Identities = 344/786 (43%), Positives = 490/786 (62%), Gaps = 31/786 (3%)

Query: 26  LPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAP 85
           L LL  LL +L    ASQ+RYSVPEE   G +VGN+++ L LE R L    +RI   G  
Sbjct: 13  LVLLCSLLGMLWEARASQIRYSVPEETEKGYIVGNISKDLALEPRELAERRVRIVSRGRT 72

Query: 86  SPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNS 145
             +   L+  SG L    RIDRE LC Q PRCL++ +VL  + V +  +E+E+ DIND++
Sbjct: 73  --QLFSLNPRSGTLVTAGRIDREELCAQSPRCLVNFKVLVEDRVKLYGIEIEVTDINDSA 130

Query: 146 PRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSK 205
           P+F   + +++++E   PGAR+ +  A DPDVG NS+Q+Y+LSP+ HF L+++     + 
Sbjct: 131 PKFQAESLEVKINEIAVPGARYPLPEAIDPDVGVNSLQSYQLSPNHHFSLNVQTGDNGAI 190

Query: 206 VLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQ 265
             ELVL + LDRE+A  HHLVLTA DGG P RS T +I V VLDTNDN+P F Q  YRV+
Sbjct: 191 NPELVLERALDREEATAHHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAPVFAQRIYRVK 250

Query: 266 LREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDY 325
           + E+ PPGT ++   ASD DEG NG++ Y      ++++  LF ++ +TGE+     LDY
Sbjct: 251 VLENVPPGTWLLTATASDLDEGINGKVAYKFWK-INEKQSLLFQLNENTGEISTAKSLDY 309

Query: 326 EEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVA 385
           EE S Y++ +QA D G   + G  KVL+ + DVNDN PEV +T L+SPV E+A   T++ 
Sbjct: 310 EECSFYEMEIQAEDGG--GLKGWTKVLISVEDVNDNRPEVTITSLFSPVREDAPQGTVIL 367

Query: 386 VLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDG 444
           + + +D+DSG N +V   ++  L F L N   + Y L+ +  LDRE+ + YNITVTATD 
Sbjct: 368 LFNAHDRDSGKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKASEYNITVTATDR 427

Query: 445 GIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEV 504
           G P L++   + ++++DINDNPP+F + SYS+Y+ ENN  G  + +V A DPD  EN+ V
Sbjct: 428 GTPPLSTEIHITLQVTDINDNPPAFSQASYSVYLPENNARGTSIFSVIAYDPDSNENSRV 487

Query: 505 TYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVT 564
            YSL E  IQG P+++YVSINS +G LYA+ SFDYE+FR+  + V A D GSPPLSS V+
Sbjct: 488 IYSLAEDTIQGSPLSTYVSINSDTGVLYALCSFDYEQFRDLQMQVTASDSGSPPLSSNVS 547

Query: 565 ANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH 623
             ++V+D ND+AP ILYP   T+ S   E+ PR+A  GYLVTKV+A+D DSGQNAWL Y 
Sbjct: 548 LRLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYR 607

Query: 624 LAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDR 683
           L + S+  LF V LHTGE+RT R + D      +L V V+D+G+P LSA+V +TVA+ D 
Sbjct: 608 LFKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAIADS 667

Query: 684 VSKILPDT-QRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACC 742
           +  IL D     + +    S++TLYL++A++ VS +FL  +I L  ++            
Sbjct: 668 IPDILADLGSLQIPADLEASDLTLYLVVAVAVVSCVFLTFVITLLALR------------ 715

Query: 743 GGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSG 802
                +R    + L +  ++ + A +P       HF+ V G  +  +TY  +  LTA S 
Sbjct: 716 -----LRHWHSSHLLRATSDGL-AGVP-----TSHFVGVDGVRAFLQTYSQEFSLTADSR 764

Query: 803 SDTFMF 808
               +F
Sbjct: 765 KSHLIF 770


>gi|14270487 protocadherin gamma subfamily A, 9 isoform 2 precursor
           [Homo sapiens]
          Length = 828

 Score =  617 bits (1592), Expect = e-176
 Identities = 344/786 (43%), Positives = 490/786 (62%), Gaps = 31/786 (3%)

Query: 26  LPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAP 85
           L LL  LL +L    ASQ+RYSVPEE   G +VGN+++ L LE R L    +RI   G  
Sbjct: 13  LVLLCSLLGMLWEARASQIRYSVPEETEKGYIVGNISKDLALEPRELAERRVRIVSRGRT 72

Query: 86  SPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNS 145
             +   L+  SG L    RIDRE LC Q PRCL++ +VL  + V +  +E+E+ DIND++
Sbjct: 73  --QLFSLNPRSGTLVTAGRIDREELCAQSPRCLVNFKVLVEDRVKLYGIEIEVTDINDSA 130

Query: 146 PRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSK 205
           P+F   + +++++E   PGAR+ +  A DPDVG NS+Q+Y+LSP+ HF L+++     + 
Sbjct: 131 PKFQAESLEVKINEIAVPGARYPLPEAIDPDVGVNSLQSYQLSPNHHFSLNVQTGDNGAI 190

Query: 206 VLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQ 265
             ELVL + LDRE+A  HHLVLTA DGG P RS T +I V VLDTNDN+P F Q  YRV+
Sbjct: 191 NPELVLERALDREEATAHHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAPVFAQRIYRVK 250

Query: 266 LREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDY 325
           + E+ PPGT ++   ASD DEG NG++ Y      ++++  LF ++ +TGE+     LDY
Sbjct: 251 VLENVPPGTWLLTATASDLDEGINGKVAYKFWK-INEKQSLLFQLNENTGEISTAKSLDY 309

Query: 326 EEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVA 385
           EE S Y++ +QA D G   + G  KVL+ + DVNDN PEV +T L+SPV E+A   T++ 
Sbjct: 310 EECSFYEMEIQAEDGG--GLKGWTKVLISVEDVNDNRPEVTITSLFSPVREDAPQGTVIL 367

Query: 386 VLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDG 444
           + + +D+DSG N +V   ++  L F L N   + Y L+ +  LDRE+ + YNITVTATD 
Sbjct: 368 LFNAHDRDSGKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKASEYNITVTATDR 427

Query: 445 GIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEV 504
           G P L++   + ++++DINDNPP+F + SYS+Y+ ENN  G  + +V A DPD  EN+ V
Sbjct: 428 GTPPLSTEIHITLQVTDINDNPPAFSQASYSVYLPENNARGTSIFSVIAYDPDSNENSRV 487

Query: 505 TYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVT 564
            YSL E  IQG P+++YVSINS +G LYA+ SFDYE+FR+  + V A D GSPPLSS V+
Sbjct: 488 IYSLAEDTIQGSPLSTYVSINSDTGVLYALCSFDYEQFRDLQMQVTASDSGSPPLSSNVS 547

Query: 565 ANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH 623
             ++V+D ND+AP ILYP   T+ S   E+ PR+A  GYLVTKV+A+D DSGQNAWL Y 
Sbjct: 548 LRLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYR 607

Query: 624 LAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDR 683
           L + S+  LF V LHTGE+RT R + D      +L V V+D+G+P LSA+V +TVA+ D 
Sbjct: 608 LFKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAIADS 667

Query: 684 VSKILPDT-QRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACC 742
           +  IL D     + +    S++TLYL++A++ VS +FL  +I L  ++            
Sbjct: 668 IPDILADLGSLQIPADLEASDLTLYLVVAVAVVSCVFLTFVITLLALR------------ 715

Query: 743 GGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSG 802
                +R    + L +  ++ + A +P       HF+ V G  +  +TY  +  LTA S 
Sbjct: 716 -----LRHWHSSHLLRATSDGL-AGVP-----TSHFVGVDGVRAFLQTYSQEFSLTADSR 764

Query: 803 SDTFMF 808
               +F
Sbjct: 765 KSHLIF 770


>gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor
           [Homo sapiens]
          Length = 936

 Score =  617 bits (1591), Expect = e-176
 Identities = 347/788 (44%), Positives = 485/788 (61%), Gaps = 38/788 (4%)

Query: 28  LLLLLLLLLPGPA-ASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPS 86
           +LL L   +P  A A Q+ YS+PEE   G+ VGN+++ LGL  R L    +RI   G   
Sbjct: 18  VLLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGRT- 76

Query: 87  PRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSP 146
            +   L+  SG+L    RIDRE LC Q  RC++S  +L  + V +  +E+E+ DINDN+P
Sbjct: 77  -QLFSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAP 135

Query: 147 RFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKV 206
           +F   N  ++++E+VA G RF +  A DPDVG NS+Q+Y+LSP++HF L ++      K 
Sbjct: 136 KFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKY 195

Query: 207 LELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQL 266
            ELVL   LDRE+ A+HHLVLTA DGG P RSGT  +SV V D NDN+P F    YRV +
Sbjct: 196 PELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSV 255

Query: 267 REDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYE 326
            E+ P GT ++ + A+D DEG+NGE+ YS      D +   F ++  TGE+++   LDYE
Sbjct: 256 PENLPVGTQLLTVTATDRDEGANGEVTYSFRK-LPDTQLLKFQLNKYTGEIKISENLDYE 314

Query: 327 EASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAV 386
           E   Y+I +QA D G        KVL+ + DVNDN+PE+ +T L+SPV E++   T+VA+
Sbjct: 315 ETGFYEIEIQAEDGG--AYLATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVAL 372

Query: 387 LSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGG 445
           L+V+D DS  N +V+  + A LPF+L     + Y LV+   LDRE+V+ YNITVTATDGG
Sbjct: 373 LNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGG 432

Query: 446 IPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVT 505
            P L++     ++++DINDNPP+F + SY  YI ENN  G  + +V A DPD KENA++ 
Sbjct: 433 SPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQII 492

Query: 506 YSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTA 565
           YSL E  IQG+P++SY+SINS +G LYA+ SFDYE+F E  + V A D G PPLSS V+ 
Sbjct: 493 YSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSL 552

Query: 566 NVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHL 624
           +++V+D ND+AP ILYP   T+ S   E+ PR+A  GYLVTKV+A+D DSGQNAWL Y L
Sbjct: 553 SLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRL 612

Query: 625 AQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRV 684
            + S+  LF V  HTGE+RT R + D      +L V V+D+G+P LSA+V +TVAV D +
Sbjct: 613 LKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSI 672

Query: 685 SKILPDTQRHVKSPRT--YSEITLYLIIALSTVSFIFLLTIIILSIIKCYRY--TAYGTA 740
            ++L D     +SP     S++TLYL++A++ VS +FL  +I+L   +  R+  +    A
Sbjct: 673 PQVLADL-GSFESPANSETSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLRRWHKSRLLQA 731

Query: 741 CCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAG 800
             GG  GV                            HF+ V G  +  +TY ++  LTA 
Sbjct: 732 SGGGLTGVS-------------------------GSHFVGVDGVRAFLQTYSHEVSLTAD 766

Query: 801 SGSDTFMF 808
           S     +F
Sbjct: 767 SRKSHLIF 774



 Score =  143 bits (360), Expect = 8e-34
 Identities = 143/532 (26%), Positives = 233/532 (43%), Gaps = 97/532 (18%)

Query: 209 LVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRE 268
           +  ++   +E      LVL  +  GIP  +G  QIS  + +               +L +
Sbjct: 1   MAAQRNRSKESKDCSGLVLLCLFFGIPWEAGARQISYSIPE---------------ELEK 45

Query: 269 DSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEE- 327
            S  G +   L  +  +    G          S    QLFS++  +G +   G +D EE 
Sbjct: 46  GSFVGNISKDLGLAPRELAERG------VRIVSRGRTQLFSLNPRSGSLITAGRIDREEL 99

Query: 328 -------ASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAP------------EVVLT 368
                    S+ I V+  DR  V + G   + +++ D+NDNAP            E V  
Sbjct: 100 CAQSARCVVSFNILVE--DR--VKLFG---IEIEVTDINDNAPKFQAENLDVKINENVAA 152

Query: 369 DLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYTLVVSGPLD 428
            +  P+PE   P+  V V S+      PN+  SL +++    R NG      LV+   LD
Sbjct: 153 GMRFPLPEAIDPD--VGVNSLQSYQLSPNKHFSLRVQS----RANGV-KYPELVLEHSLD 205

Query: 429 RERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLL 488
           RE  A++++ +TA+DGG P  +    + V + D NDN P F    Y + + EN   G  L
Sbjct: 206 REEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLPVGTQL 265

Query: 489 CTVQATDPDEKENAEVTYSLLEREIQGLPVTSYV--SINSASGSLYAVNSFDYEKFREFF 546
            TV ATD DE  N EVTYS      + LP T  +   +N  +G +    + DYE+   + 
Sbjct: 266 LTVTATDRDEGANGEVTYS-----FRKLPDTQLLKFQLNKYTGEIKISENLDYEETGFYE 320

Query: 547 VTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTK 606
           + ++A+D G+    +T    + V D+ND++P +        ++ F  V   +P G +V  
Sbjct: 321 IEIQAEDGGA--YLATAKVLITVEDVNDNSPEL------TITSLFSPVTEDSPLGTVVAL 372

Query: 607 VIAMDSDSGQN--------AWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNL 658
           +   D DS QN        A+L + L ++ D   +++ +H       R +  E  S++N+
Sbjct: 373 LNVHDLDSEQNGQVTCSILAYLPFKLEKSID-SYYRLVIH-------RALDREQVSSYNI 424

Query: 659 TVVVRDNGEPSLSASVAITVAVVDRVSKILPDTQRHVKSPRTYSEITLYLII 710
           TV   D G P LS      + V D     + D      +P T+S+++ +  I
Sbjct: 425 TVTATDGGSPPLSTEAHFMLQVAD-----IND------NPPTFSQVSYFTYI 465


>gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precursor
           [Homo sapiens]
          Length = 850

 Score =  617 bits (1591), Expect = e-176
 Identities = 347/788 (44%), Positives = 485/788 (61%), Gaps = 38/788 (4%)

Query: 28  LLLLLLLLLPGPA-ASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPS 86
           +LL L   +P  A A Q+ YS+PEE   G+ VGN+++ LGL  R L    +RI   G   
Sbjct: 18  VLLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGRT- 76

Query: 87  PRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSP 146
            +   L+  SG+L    RIDRE LC Q  RC++S  +L  + V +  +E+E+ DINDN+P
Sbjct: 77  -QLFSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAP 135

Query: 147 RFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKV 206
           +F   N  ++++E+VA G RF +  A DPDVG NS+Q+Y+LSP++HF L ++      K 
Sbjct: 136 KFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKY 195

Query: 207 LELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQL 266
            ELVL   LDRE+ A+HHLVLTA DGG P RSGT  +SV V D NDN+P F    YRV +
Sbjct: 196 PELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSV 255

Query: 267 REDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYE 326
            E+ P GT ++ + A+D DEG+NGE+ YS      D +   F ++  TGE+++   LDYE
Sbjct: 256 PENLPVGTQLLTVTATDRDEGANGEVTYSFRK-LPDTQLLKFQLNKYTGEIKISENLDYE 314

Query: 327 EASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAV 386
           E   Y+I +QA D G        KVL+ + DVNDN+PE+ +T L+SPV E++   T+VA+
Sbjct: 315 ETGFYEIEIQAEDGG--AYLATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVAL 372

Query: 387 LSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGG 445
           L+V+D DS  N +V+  + A LPF+L     + Y LV+   LDRE+V+ YNITVTATDGG
Sbjct: 373 LNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGG 432

Query: 446 IPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVT 505
            P L++     ++++DINDNPP+F + SY  YI ENN  G  + +V A DPD KENA++ 
Sbjct: 433 SPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQII 492

Query: 506 YSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTA 565
           YSL E  IQG+P++SY+SINS +G LYA+ SFDYE+F E  + V A D G PPLSS V+ 
Sbjct: 493 YSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSL 552

Query: 566 NVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHL 624
           +++V+D ND+AP ILYP   T+ S   E+ PR+A  GYLVTKV+A+D DSGQNAWL Y L
Sbjct: 553 SLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRL 612

Query: 625 AQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRV 684
            + S+  LF V  HTGE+RT R + D      +L V V+D+G+P LSA+V +TVAV D +
Sbjct: 613 LKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSI 672

Query: 685 SKILPDTQRHVKSPRT--YSEITLYLIIALSTVSFIFLLTIIILSIIKCYRY--TAYGTA 740
            ++L D     +SP     S++TLYL++A++ VS +FL  +I+L   +  R+  +    A
Sbjct: 673 PQVLADL-GSFESPANSETSDLTLYLVVAVAAVSCVFLAFVIVLLAHRLRRWHKSRLLQA 731

Query: 741 CCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAG 800
             GG  GV                            HF+ V G  +  +TY ++  LTA 
Sbjct: 732 SGGGLTGVS-------------------------GSHFVGVDGVRAFLQTYSHEVSLTAD 766

Query: 801 SGSDTFMF 808
           S     +F
Sbjct: 767 SRKSHLIF 774



 Score =  143 bits (360), Expect = 8e-34
 Identities = 143/532 (26%), Positives = 233/532 (43%), Gaps = 97/532 (18%)

Query: 209 LVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRE 268
           +  ++   +E      LVL  +  GIP  +G  QIS  + +               +L +
Sbjct: 1   MAAQRNRSKESKDCSGLVLLCLFFGIPWEAGARQISYSIPE---------------ELEK 45

Query: 269 DSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEE- 327
            S  G +   L  +  +    G          S    QLFS++  +G +   G +D EE 
Sbjct: 46  GSFVGNISKDLGLAPRELAERG------VRIVSRGRTQLFSLNPRSGSLITAGRIDREEL 99

Query: 328 -------ASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAP------------EVVLT 368
                    S+ I V+  DR  V + G   + +++ D+NDNAP            E V  
Sbjct: 100 CAQSARCVVSFNILVE--DR--VKLFG---IEIEVTDINDNAPKFQAENLDVKINENVAA 152

Query: 369 DLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYTLVVSGPLD 428
            +  P+PE   P+  V V S+      PN+  SL +++    R NG      LV+   LD
Sbjct: 153 GMRFPLPEAIDPD--VGVNSLQSYQLSPNKHFSLRVQS----RANGV-KYPELVLEHSLD 205

Query: 429 RERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLL 488
           RE  A++++ +TA+DGG P  +    + V + D NDN P F    Y + + EN   G  L
Sbjct: 206 REEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLPVGTQL 265

Query: 489 CTVQATDPDEKENAEVTYSLLEREIQGLPVTSYV--SINSASGSLYAVNSFDYEKFREFF 546
            TV ATD DE  N EVTYS      + LP T  +   +N  +G +    + DYE+   + 
Sbjct: 266 LTVTATDRDEGANGEVTYS-----FRKLPDTQLLKFQLNKYTGEIKISENLDYEETGFYE 320

Query: 547 VTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTK 606
           + ++A+D G+    +T    + V D+ND++P +        ++ F  V   +P G +V  
Sbjct: 321 IEIQAEDGGA--YLATAKVLITVEDVNDNSPEL------TITSLFSPVTEDSPLGTVVAL 372

Query: 607 VIAMDSDSGQN--------AWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNL 658
           +   D DS QN        A+L + L ++ D   +++ +H       R +  E  S++N+
Sbjct: 373 LNVHDLDSEQNGQVTCSILAYLPFKLEKSID-SYYRLVIH-------RALDREQVSSYNI 424

Query: 659 TVVVRDNGEPSLSASVAITVAVVDRVSKILPDTQRHVKSPRTYSEITLYLII 710
           TV   D G P LS      + V D     + D      +P T+S+++ +  I
Sbjct: 425 TVTATDGGSPPLSTEAHFMLQVAD-----IND------NPPTFSQVSYFTYI 465


>gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  608 bits (1567), Expect = e-174
 Identities = 340/786 (43%), Positives = 477/786 (60%), Gaps = 31/786 (3%)

Query: 26  LPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAP 85
           L LL  LL  L    + Q+RYSV EE   G+ VGN+A  LGLE R L    +RI   G  
Sbjct: 13  LALLCALLGTLCETGSGQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSRGRT 72

Query: 86  SPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNS 145
             +   L+  SG+L   ERIDRE LC Q P CL+ + +L  + + +  VE+EI DINDN+
Sbjct: 73  --QLFSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDNA 130

Query: 146 PRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSK 205
           P FP    ++++ E   PG RF I++A DPDVG NS+Q Y+LSP+++F L +  + E +K
Sbjct: 131 PNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGAK 190

Query: 206 VLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQ 265
             ELVL + LDRE+  +H LVL A DGG P  SG   I V VLD NDN P F Q  YRV 
Sbjct: 191 YPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVS 250

Query: 266 LREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDY 325
           + E+ P GT ++ +NA+DPDEG N ++ Y L      +  ++F +++ +GEV ++  LDY
Sbjct: 251 VWENVPVGTRLLTVNATDPDEGFNAQVSYILDKMPG-KIAEIFHLNSVSGEVSILKSLDY 309

Query: 326 EEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVA 385
           E+A  Y+I ++A D GP  +    K+LV ++DVNDNAPE+ +T L S VPE  T    +A
Sbjct: 310 EDAMFYEIKIEAQD-GP-GLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGREIA 367

Query: 386 VLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDG 444
           ++ V+D+DSG N +V + +   LPF+L       Y LV +  LDRE+++ YNI++ A+DG
Sbjct: 368 LIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASDG 427

Query: 445 GIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEV 504
           G P L++   + + + DINDNPP+F   SYS YI ENN  G  + +V A DPD   NA +
Sbjct: 428 GSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNARI 487

Query: 505 TYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVT 564
           TY+L E  +QG P++S+VSINS +G LYA+ SFDYE+FR+  + V A D G+PPLSS V+
Sbjct: 488 TYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNVS 547

Query: 565 ANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH 623
            N++V+D ND+AP ILYP   T+ S   E+ PR+A  GYLVTKV+A+D DSGQNAWL Y 
Sbjct: 548 LNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYR 607

Query: 624 LAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDR 683
           L + S+  LF V LHTGE+RT R + D      +L V V+D+G+P LSA+V +TVAV DR
Sbjct: 608 LLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADR 667

Query: 684 VSKILPDTQRHVKSPR-TYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACC 742
           +  IL D      S +   S++TLYL++A++ VS +FL  +I+L  ++  R+        
Sbjct: 668 IPDILADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLRRWHKSRLLQA 727

Query: 743 GGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSG 802
            G  G    +P                       HF+   G  +  +TY ++  LTA S 
Sbjct: 728 SG--GGLASTPGS---------------------HFVGADGVRAFLQTYSHEVSLTADSR 764

Query: 803 SDTFMF 808
               +F
Sbjct: 765 KSHLIF 770


>gi|14196465 protocadherin gamma subfamily A, 3 isoform 2 precursor
           [Homo sapiens]
          Length = 829

 Score =  608 bits (1567), Expect = e-174
 Identities = 340/786 (43%), Positives = 477/786 (60%), Gaps = 31/786 (3%)

Query: 26  LPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAP 85
           L LL  LL  L    + Q+RYSV EE   G+ VGN+A  LGLE R L    +RI   G  
Sbjct: 13  LALLCALLGTLCETGSGQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSRGRT 72

Query: 86  SPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNS 145
             +   L+  SG+L   ERIDRE LC Q P CL+ + +L  + + +  VE+EI DINDN+
Sbjct: 73  --QLFSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDNA 130

Query: 146 PRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSK 205
           P FP    ++++ E   PG RF I++A DPDVG NS+Q Y+LSP+++F L +  + E +K
Sbjct: 131 PNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGAK 190

Query: 206 VLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQ 265
             ELVL + LDRE+  +H LVL A DGG P  SG   I V VLD NDN P F Q  YRV 
Sbjct: 191 YPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVS 250

Query: 266 LREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDY 325
           + E+ P GT ++ +NA+DPDEG N ++ Y L      +  ++F +++ +GEV ++  LDY
Sbjct: 251 VWENVPVGTRLLTVNATDPDEGFNAQVSYILDKMPG-KIAEIFHLNSVSGEVSILKSLDY 309

Query: 326 EEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVA 385
           E+A  Y+I ++A D GP  +    K+LV ++DVNDNAPE+ +T L S VPE  T    +A
Sbjct: 310 EDAMFYEIKIEAQD-GP-GLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGREIA 367

Query: 386 VLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDG 444
           ++ V+D+DSG N +V + +   LPF+L       Y LV +  LDRE+++ YNI++ A+DG
Sbjct: 368 LIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASDG 427

Query: 445 GIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEV 504
           G P L++   + + + DINDNPP+F   SYS YI ENN  G  + +V A DPD   NA +
Sbjct: 428 GSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNARI 487

Query: 505 TYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVT 564
           TY+L E  +QG P++S+VSINS +G LYA+ SFDYE+FR+  + V A D G+PPLSS V+
Sbjct: 488 TYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNVS 547

Query: 565 ANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH 623
            N++V+D ND+AP ILYP   T+ S   E+ PR+A  GYLVTKV+A+D DSGQNAWL Y 
Sbjct: 548 LNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYR 607

Query: 624 LAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDR 683
           L + S+  LF V LHTGE+RT R + D      +L V V+D+G+P LSA+V +TVAV DR
Sbjct: 608 LLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADR 667

Query: 684 VSKILPDTQRHVKSPR-TYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACC 742
           +  IL D      S +   S++TLYL++A++ VS +FL  +I+L  ++  R+        
Sbjct: 668 IPDILADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLRRWHKSRLLQA 727

Query: 743 GGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSG 802
            G  G    +P                       HF+   G  +  +TY ++  LTA S 
Sbjct: 728 SG--GGLASTPGS---------------------HFVGADGVRAFLQTYSHEVSLTADSR 764

Query: 803 SDTFMF 808
               +F
Sbjct: 765 KSHLIF 770


>gi|11056032 protocadherin gamma subfamily A, 1 isoform 1 precursor
           [Homo sapiens]
          Length = 931

 Score =  607 bits (1566), Expect = e-173
 Identities = 344/786 (43%), Positives = 482/786 (61%), Gaps = 31/786 (3%)

Query: 26  LPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAP 85
           L LL L L LL    A  + YSVPEE   G+ VGN+A+ LGL+ + L  G +RI   G  
Sbjct: 13  LMLLCLSLELLLEAGAGNIHYSVPEETDKGSFVGNIAKDLGLQPQELADGGVRIVSRGRM 72

Query: 86  SPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNS 145
                 L+  SG+L    RIDRE LC Q   CL+S  +L  + + +  VEVEI+DINDN+
Sbjct: 73  P--LFALNPRSGSLITARRIDREELCAQSMPCLVSFNILVEDKMKLFPVEVEIIDINDNT 130

Query: 146 PRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSK 205
           P+F     + +++E   PG R  +   QD DVG NS+Q+Y+LS + HF LD++   +  +
Sbjct: 131 PQFQLEELEFKMNEITTPGTRVSLPFGQDLDVGMNSLQSYQLSSNPHFSLDVQQGADGPQ 190

Query: 206 VLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQ 265
             E+VL+  LDRE+ A+HHL+LTA DGG P RSGT +I ++V+D NDN PAF Q+ Y + 
Sbjct: 191 HPEMVLQSPLDREEEAVHHLILTASDGGEPVRSGTLRIYIQVVDANDNPPAFTQAQYHIN 250

Query: 266 LREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDY 325
           + E+ P GT ++ +NA+DPDEG+NGE+ YS  +    R  Q+F +D+ TGE+     LD+
Sbjct: 251 VPENVPLGTQLLMVNATDPDEGANGEVTYSFHN-VDHRVAQIFRLDSYTGEISNKEPLDF 309

Query: 326 EEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVA 385
           EE   Y + VQA D     +    KVL+ ++DVNDNAPEV +T + + VPEN  P TI+A
Sbjct: 310 EEYKMYSMEVQAQD--GAGLMAKVKVLIKVLDVNDNAPEVTITSVTTAVPENFPPGTIIA 367

Query: 386 VLSVNDQDSGPNRKVSLGLEATLPFRLNGF-GNSYTLVVSGPLDRERVAVYNITVTATDG 444
           ++SV+DQDSG N   +  +   LPF+L     N Y LV    LDRE ++ YNIT+TA D 
Sbjct: 368 LISVHDQDSGDNGYTTCFIPGNLPFKLEKLVDNYYRLVTERTLDRELISGYNITITAIDQ 427

Query: 445 GIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEV 504
           G P L++   + + ++DINDN P F +DSYS YI ENN  G  + +V+A D D  ENA++
Sbjct: 428 GTPALSTETHISLLVTDINDNSPVFHQDSYSAYIPENNPRGASIFSVRAHDLDSNENAQI 487

Query: 505 TYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVT 564
           TYSL+E  IQG P+++Y+SINS +G LYA+ SFDYE+FR+  + V A+D G PPLSS V+
Sbjct: 488 TYSLIEDTIQGAPLSAYLSINSDTGVLYALRSFDYEQFRDMQLKVMARDSGDPPLSSNVS 547

Query: 565 ANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH 623
            +++++D ND+AP ILYP   T+ S   E+ P +A  GYLVTKV+A+D DSGQNAWL Y 
Sbjct: 548 LSLFLLDQNDNAPEILYPALPTDGSTGVELAPLSAEPGYLVTKVVAVDRDSGQNAWLSYR 607

Query: 624 LAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDR 683
           L + S+  LF V LHTGE+RT R + D      +L V V+D+G+P LSA+V +TVAV DR
Sbjct: 608 LLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADR 667

Query: 684 VSKILPDTQRHVKSPR-TYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACC 742
           +S IL D      S +   S++TLYL++A + VS +FL  +I+L   +  R+        
Sbjct: 668 ISDILADLGSLEPSAKPNDSDLTLYLVVAAAAVSCVFLAFVIVLLAHRLRRW-------- 719

Query: 743 GGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSG 802
                           QA+    A +P       HF+ V G  +  +TY ++  LTA S 
Sbjct: 720 ----------HKSRLLQASGGGLASMPGS-----HFVGVDGVRAFLQTYSHEVSLTADSR 764

Query: 803 SDTFMF 808
               +F
Sbjct: 765 KSHLIF 770


>gi|14196459 protocadherin gamma subfamily A, 1 isoform 2 precursor
           [Homo sapiens]
          Length = 823

 Score =  607 bits (1566), Expect = e-173
 Identities = 344/786 (43%), Positives = 482/786 (61%), Gaps = 31/786 (3%)

Query: 26  LPLLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAP 85
           L LL L L LL    A  + YSVPEE   G+ VGN+A+ LGL+ + L  G +RI   G  
Sbjct: 13  LMLLCLSLELLLEAGAGNIHYSVPEETDKGSFVGNIAKDLGLQPQELADGGVRIVSRGRM 72

Query: 86  SPRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNS 145
                 L+  SG+L    RIDRE LC Q   CL+S  +L  + + +  VEVEI+DINDN+
Sbjct: 73  P--LFALNPRSGSLITARRIDREELCAQSMPCLVSFNILVEDKMKLFPVEVEIIDINDNT 130

Query: 146 PRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSK 205
           P+F     + +++E   PG R  +   QD DVG NS+Q+Y+LS + HF LD++   +  +
Sbjct: 131 PQFQLEELEFKMNEITTPGTRVSLPFGQDLDVGMNSLQSYQLSSNPHFSLDVQQGADGPQ 190

Query: 206 VLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQ 265
             E+VL+  LDRE+ A+HHL+LTA DGG P RSGT +I ++V+D NDN PAF Q+ Y + 
Sbjct: 191 HPEMVLQSPLDREEEAVHHLILTASDGGEPVRSGTLRIYIQVVDANDNPPAFTQAQYHIN 250

Query: 266 LREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDY 325
           + E+ P GT ++ +NA+DPDEG+NGE+ YS  +    R  Q+F +D+ TGE+     LD+
Sbjct: 251 VPENVPLGTQLLMVNATDPDEGANGEVTYSFHN-VDHRVAQIFRLDSYTGEISNKEPLDF 309

Query: 326 EEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVA 385
           EE   Y + VQA D     +    KVL+ ++DVNDNAPEV +T + + VPEN  P TI+A
Sbjct: 310 EEYKMYSMEVQAQD--GAGLMAKVKVLIKVLDVNDNAPEVTITSVTTAVPENFPPGTIIA 367

Query: 386 VLSVNDQDSGPNRKVSLGLEATLPFRLNGF-GNSYTLVVSGPLDRERVAVYNITVTATDG 444
           ++SV+DQDSG N   +  +   LPF+L     N Y LV    LDRE ++ YNIT+TA D 
Sbjct: 368 LISVHDQDSGDNGYTTCFIPGNLPFKLEKLVDNYYRLVTERTLDRELISGYNITITAIDQ 427

Query: 445 GIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEV 504
           G P L++   + + ++DINDN P F +DSYS YI ENN  G  + +V+A D D  ENA++
Sbjct: 428 GTPALSTETHISLLVTDINDNSPVFHQDSYSAYIPENNPRGASIFSVRAHDLDSNENAQI 487

Query: 505 TYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVT 564
           TYSL+E  IQG P+++Y+SINS +G LYA+ SFDYE+FR+  + V A+D G PPLSS V+
Sbjct: 488 TYSLIEDTIQGAPLSAYLSINSDTGVLYALRSFDYEQFRDMQLKVMARDSGDPPLSSNVS 547

Query: 565 ANVYVVDMNDHAPHILYPT-STNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYH 623
            +++++D ND+AP ILYP   T+ S   E+ P +A  GYLVTKV+A+D DSGQNAWL Y 
Sbjct: 548 LSLFLLDQNDNAPEILYPALPTDGSTGVELAPLSAEPGYLVTKVVAVDRDSGQNAWLSYR 607

Query: 624 LAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDR 683
           L + S+  LF V LHTGE+RT R + D      +L V V+D+G+P LSA+V +TVAV DR
Sbjct: 608 LLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADR 667

Query: 684 VSKILPDTQRHVKSPR-TYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACC 742
           +S IL D      S +   S++TLYL++A + VS +FL  +I+L   +  R+        
Sbjct: 668 ISDILADLGSLEPSAKPNDSDLTLYLVVAAAAVSCVFLAFVIVLLAHRLRRW-------- 719

Query: 743 GGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSG 802
                           QA+    A +P       HF+ V G  +  +TY ++  LTA S 
Sbjct: 720 ----------HKSRLLQASGGGLASMPGS-----HFVGVDGVRAFLQTYSHEVSLTADSR 764

Query: 803 SDTFMF 808
               +F
Sbjct: 765 KSHLIF 770


>gi|14277682 protocadherin gamma subfamily C, 4 isoform 2 precursor
           [Homo sapiens]
          Length = 871

 Score =  607 bits (1564), Expect = e-173
 Identities = 330/780 (42%), Positives = 482/780 (61%), Gaps = 12/780 (1%)

Query: 30  LLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRY 89
           LL L    G    Q+RY VPEE   G  VGNVA+   L+   L    L++   G  + R+
Sbjct: 17  LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQV--AGEVNQRH 74

Query: 90  LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149
             +DL SGAL +   IDREALC     C++ LE +   P+ +   EVEI+D+ND++PRFP
Sbjct: 75  FRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFP 134

Query: 150 RPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLEL 209
           R    L++ E+  PG RF +E AQD DVG+NS+ +Y LS +EHF LD+K   + S V EL
Sbjct: 135 RQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPEL 194

Query: 210 VLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRED 269
           +L K LDRE+ + + LVLTAVDGG P RSGTA++ V VLD NDN+PAF QS+YR+ + E 
Sbjct: 195 LLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLES 254

Query: 270 SPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEAS 329
           +P G ++++LNASDPD G +G + +  S +T DR R LFS+  +TG++ ++G LD+E  +
Sbjct: 255 APAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESEN 314

Query: 330 SYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSV 389
            Y+  V+A D G   M  HC + VD++DVNDNAP + +T     +PE+A P T+VA++SV
Sbjct: 315 YYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISV 374

Query: 390 NDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQ 448
            D DSG N  VSL +   LPF L + F N ++LV +GPLDRE  + Y+I VTA+D G P 
Sbjct: 375 QDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPP 434

Query: 449 LTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508
           L++ RT+ + ISD+NDNPPSF + S+ +++ ENN PG LLC++ A+DPD   NA ++YSL
Sbjct: 435 LSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSL 494

Query: 509 LEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVY 568
           LE   + +  +S++S+N  +G+++A  SFDYE+ +     V+A+D+G+PPLSSTVT  ++
Sbjct: 495 LEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLF 554

Query: 569 VVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTS 628
           V+D+ND+AP +L P +   S   + +P +  AG+L+TKV A+D DSG NAW+ Y L +  
Sbjct: 555 VLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAP 614

Query: 629 DLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKIL 688
           D  LF V  + GE+RT   +  +      L +VV+D+G P LS SV + V++ +    ++
Sbjct: 615 DPSLFAVSRYAGEVRTAVPIPADLPPQ-KLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVV 673

Query: 689 PDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACC-GGFCG 747
           PD +         S +TLYL ++L  + F+   + + L + KC R  A G  C   G C 
Sbjct: 674 PDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVAL-LSKCLRGAACGVTCFPAGTCA 732

Query: 748 VRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDTFM 807
              RS        +N I  RI  G      F++V G+     ++      +A + SD+FM
Sbjct: 733 CLTRSRRREGLPPSNGI-LRIQLGSDDPIKFVDVGGH-----SHGCTPLASAPTRSDSFM 786


>gi|11128025 protocadherin gamma subfamily C, 4 isoform 1 precursor
           [Homo sapiens]
          Length = 938

 Score =  607 bits (1564), Expect = e-173
 Identities = 330/780 (42%), Positives = 482/780 (61%), Gaps = 12/780 (1%)

Query: 30  LLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRY 89
           LL L    G    Q+RY VPEE   G  VGNVA+   L+   L    L++   G  + R+
Sbjct: 17  LLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQV--AGEVNQRH 74

Query: 90  LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149
             +DL SGAL +   IDREALC     C++ LE +   P+ +   EVEI+D+ND++PRFP
Sbjct: 75  FRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFP 134

Query: 150 RPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLEL 209
           R    L++ E+  PG RF +E AQD DVG+NS+ +Y LS +EHF LD+K   + S V EL
Sbjct: 135 RQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPEL 194

Query: 210 VLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRED 269
           +L K LDRE+ + + LVLTAVDGG P RSGTA++ V VLD NDN+PAF QS+YR+ + E 
Sbjct: 195 LLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLES 254

Query: 270 SPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEAS 329
           +P G ++++LNASDPD G +G + +  S +T DR R LFS+  +TG++ ++G LD+E  +
Sbjct: 255 APAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESEN 314

Query: 330 SYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSV 389
            Y+  V+A D G   M  HC + VD++DVNDNAP + +T     +PE+A P T+VA++SV
Sbjct: 315 YYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISV 374

Query: 390 NDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQ 448
            D DSG N  VSL +   LPF L + F N ++LV +GPLDRE  + Y+I VTA+D G P 
Sbjct: 375 QDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPP 434

Query: 449 LTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508
           L++ RT+ + ISD+NDNPPSF + S+ +++ ENN PG LLC++ A+DPD   NA ++YSL
Sbjct: 435 LSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSL 494

Query: 509 LEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVY 568
           LE   + +  +S++S+N  +G+++A  SFDYE+ +     V+A+D+G+PPLSSTVT  ++
Sbjct: 495 LEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLF 554

Query: 569 VVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTS 628
           V+D+ND+AP +L P +   S   + +P +  AG+L+TKV A+D DSG NAW+ Y L +  
Sbjct: 555 VLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAP 614

Query: 629 DLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKIL 688
           D  LF V  + GE+RT   +  +      L +VV+D+G P LS SV + V++ +    ++
Sbjct: 615 DPSLFAVSRYAGEVRTAVPIPADLPPQ-KLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVV 673

Query: 689 PDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGTACC-GGFCG 747
           PD +         S +TLYL ++L  + F+   + + L + KC R  A G  C   G C 
Sbjct: 674 PDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVAL-LSKCLRGAACGVTCFPAGTCA 732

Query: 748 VRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTAGSGSDTFM 807
              RS        +N I  RI  G      F++V G+     ++      +A + SD+FM
Sbjct: 733 CLTRSRRREGLPPSNGI-LRIQLGSDDPIKFVDVGGH-----SHGCTPLASAPTRSDSFM 786


>gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo
           sapiens]
          Length = 814

 Score =  603 bits (1556), Expect = e-172
 Identities = 330/714 (46%), Positives = 459/714 (64%), Gaps = 15/714 (2%)

Query: 28  LLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSP 87
           LLLLLLL      + QL YSVPEE   G  VG +A+ LGLEL  L P   R+      S 
Sbjct: 15  LLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRV-----ASK 69

Query: 88  RY---LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDN 144
           R+   LE+ L +G LFVN RIDRE LC +   C + LEV+   P+ V  V+VE+ D+NDN
Sbjct: 70  RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129

Query: 145 SPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENS 204
            P F   + +L VSES  P +RF +E A D DVGANSV TY LS  ++F LD+    + +
Sbjct: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189

Query: 205 KVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRV 264
           K++ELVLRK LDRE A  HHL LTA DGG P  +GT Q+ V VLD NDN+P F+QS Y V
Sbjct: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249

Query: 265 QLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLD 324
           ++ E++  GT V+KLNASDPDEG+NG + YS +S         FSID +TGE+ + G LD
Sbjct: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309

Query: 325 YEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIV 384
           +E+ + Y+I + ATD+G  PMAGHC VLV I+D NDN PE+ LT L  PV E+A   T++
Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369

Query: 385 AVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATD 443
           A++SVND DSG N +V+  L   +PF+L + F N Y+LV+   LDRERV+ Y + VTA D
Sbjct: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429

Query: 444 GGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAE 503
           GG P L +  +L VE++D+NDN P+F +  Y+++++ENN PG  + TV A D D +ENA 
Sbjct: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489

Query: 504 VTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTV 563
           V+YSL+ER +    ++SY+S+++ SG +YA+   D+E+       V A+D G PPL S V
Sbjct: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 564 TANVYVVDMNDHAPHILYP-TSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFY 622
           T  V+V+D ND+AP +L P       AA ++VPR+  AG++V KV A+D+DSG NAWL Y
Sbjct: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 623 HL--AQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAV 680
            L  A +S    F+V L+TGEI TTR + +       L V+V+D+GEP+L+A+  + V++
Sbjct: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669

Query: 681 VD--RVSKILPDTQRHVKSPR-TYSEITLYLIIALSTVSFIFLLTIIILSIIKC 731
           V+  +  K        V  P     ++ +YLIIA+  VS + +LT+++ + ++C
Sbjct: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723


>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score =  603 bits (1556), Expect = e-172
 Identities = 330/714 (46%), Positives = 459/714 (64%), Gaps = 15/714 (2%)

Query: 28  LLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSP 87
           LLLLLLL      + QL YSVPEE   G  VG +A+ LGLEL  L P   R+      S 
Sbjct: 15  LLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRV-----ASK 69

Query: 88  RY---LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDN 144
           R+   LE+ L +G LFVN RIDRE LC +   C + LEV+   P+ V  V+VE+ D+NDN
Sbjct: 70  RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129

Query: 145 SPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENS 204
            P F   + +L VSES  P +RF +E A D DVGANSV TY LS  ++F LD+    + +
Sbjct: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189

Query: 205 KVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRV 264
           K++ELVLRK LDRE A  HHL LTA DGG P  +GT Q+ V VLD NDN+P F+QS Y V
Sbjct: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249

Query: 265 QLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLD 324
           ++ E++  GT V+KLNASDPDEG+NG + YS +S         FSID +TGE+ + G LD
Sbjct: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309

Query: 325 YEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIV 384
           +E+ + Y+I + ATD+G  PMAGHC VLV I+D NDN PE+ LT L  PV E+A   T++
Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369

Query: 385 AVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATD 443
           A++SVND DSG N +V+  L   +PF+L + F N Y+LV+   LDRERV+ Y + VTA D
Sbjct: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429

Query: 444 GGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAE 503
           GG P L +  +L VE++D+NDN P+F +  Y+++++ENN PG  + TV A D D +ENA 
Sbjct: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489

Query: 504 VTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTV 563
           V+YSL+ER +    ++SY+S+++ SG +YA+   D+E+       V A+D G PPL S V
Sbjct: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 564 TANVYVVDMNDHAPHILYP-TSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFY 622
           T  V+V+D ND+AP +L P       AA ++VPR+  AG++V KV A+D+DSG NAWL Y
Sbjct: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 623 HL--AQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAV 680
            L  A +S    F+V L+TGEI TTR + +       L V+V+D+GEP+L+A+  + V++
Sbjct: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669

Query: 681 VD--RVSKILPDTQRHVKSPR-TYSEITLYLIIALSTVSFIFLLTIIILSIIKC 731
           V+  +  K        V  P     ++ +YLIIA+  VS + +LT+++ + ++C
Sbjct: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723


>gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precursor
           [Homo sapiens]
          Length = 863

 Score =  602 bits (1552), Expect = e-172
 Identities = 311/706 (44%), Positives = 456/706 (64%), Gaps = 5/706 (0%)

Query: 30  LLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRY 89
           +LLLL     A++ + Y +PEE+  G  VGNV   LGL+L  L     R+  +   S R+
Sbjct: 19  VLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRV--VSGASRRF 76

Query: 90  LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149
            E++  +G +FVN+R+DRE LC   P C ++LE++  NP+ + +VEV I DINDN+P FP
Sbjct: 77  FEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFP 136

Query: 150 RPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLEL 209
               +L++SE+VAPG RF +ESA DPDVG+NS+QTYELS +E+F L ++  ++++K  EL
Sbjct: 137 TQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAEL 196

Query: 210 VLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRED 269
           VL + LDRE+     LVLTA+DGG PA S +  I ++VLD NDN+P F+QS YR ++ ED
Sbjct: 197 VLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLED 256

Query: 270 SPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEAS 329
           +P GT VV++ A+D DEG NGE+ YS  S+     RQLF++D  TG + + G LD+E+  
Sbjct: 257 APSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTK 316

Query: 330 SYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSV 389
            ++IY+QA D+G  P   HCKVLV++VDVNDNAPE+ +T +YSPVPE+A   T++A+LSV
Sbjct: 317 LHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSV 376

Query: 390 NDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQ 448
            D D+G N  V+  +   LPF L +   N +TL  S  LDRE V  YN+++TA D G P 
Sbjct: 377 TDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPS 436

Query: 449 LTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508
           L++L  ++V++SDINDNPP   + SY +YI+ENNLPG  +  +   DPD  +NA +++ L
Sbjct: 437 LSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFL 496

Query: 509 LEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVY 568
           LE+  +   V  Y +IN  +G + ++   DYE  REF +T    D G+P L++ ++ N++
Sbjct: 497 LEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIF 556

Query: 569 VVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTS 628
           V D ND+AP +LYP    SS   EM+PR   AG+LV++V+  D+D+G NAWL Y L  + 
Sbjct: 557 VTDRNDNAPQVLYPRPGGSSV--EMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSP 614

Query: 629 DLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKIL 688
           +  LF + LHTG+I T R + D       LTV+++DNGEPSLS +  +TV+V +   +  
Sbjct: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEAR 674

Query: 689 PDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRY 734
            +             +T YL+++L  VS  F++T+  + I K Y++
Sbjct: 675 AEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW 720


>gi|14277675 protocadherin gamma subfamily C, 3 isoform 1 precursor
           [Homo sapiens]
          Length = 934

 Score =  602 bits (1552), Expect = e-172
 Identities = 311/706 (44%), Positives = 456/706 (64%), Gaps = 5/706 (0%)

Query: 30  LLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSPRY 89
           +LLLL     A++ + Y +PEE+  G  VGNV   LGL+L  L     R+  +   S R+
Sbjct: 19  VLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSARRFRV--VSGASRRF 76

Query: 90  LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149
            E++  +G +FVN+R+DRE LC   P C ++LE++  NP+ + +VEV I DINDN+P FP
Sbjct: 77  FEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVVIQDINDNNPAFP 136

Query: 150 RPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLEL 209
               +L++SE+VAPG RF +ESA DPDVG+NS+QTYELS +E+F L ++  ++++K  EL
Sbjct: 137 TQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRVQTREDSTKYAEL 196

Query: 210 VLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRED 269
           VL + LDRE+     LVLTA+DGG PA S +  I ++VLD NDN+P F+QS YR ++ ED
Sbjct: 197 VLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVFNQSLYRARVLED 256

Query: 270 SPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEAS 329
           +P GT VV++ A+D DEG NGE+ YS  S+     RQLF++D  TG + + G LD+E+  
Sbjct: 257 APSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGMLTIKGRLDFEDTK 316

Query: 330 SYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSV 389
            ++IY+QA D+G  P   HCKVLV++VDVNDNAPE+ +T +YSPVPE+A   T++A+LSV
Sbjct: 317 LHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSV 376

Query: 390 NDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQ 448
            D D+G N  V+  +   LPF L +   N +TL  S  LDRE V  YN+++TA D G P 
Sbjct: 377 TDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYNLSITARDAGTPS 436

Query: 449 LTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL 508
           L++L  ++V++SDINDNPP   + SY +YI+ENNLPG  +  +   DPD  +NA +++ L
Sbjct: 437 LSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDPDAPQNARLSFFL 496

Query: 509 LEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVY 568
           LE+  +   V  Y +IN  +G + ++   DYE  REF +T    D G+P L++ ++ N++
Sbjct: 497 LEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGTPVLATNISVNIF 556

Query: 569 VVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTS 628
           V D ND+AP +LYP    SS   EM+PR   AG+LV++V+  D+D+G NAWL Y L  + 
Sbjct: 557 VTDRNDNAPQVLYPRPGGSSV--EMLPRGTSAGHLVSRVVGWDADAGHNAWLSYSLLGSP 614

Query: 629 DLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVDRVSKIL 688
           +  LF + LHTG+I T R + D       LTV+++DNGEPSLS +  +TV+V +   +  
Sbjct: 615 NQSLFAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTTATLTVSVTEDSPEAR 674

Query: 689 PDTQRHVKSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRY 734
            +             +T YL+++L  VS  F++T+  + I K Y++
Sbjct: 675 AEFPSGSAPREQKKNLTFYLLLSLILVSVGFVVTVFGVIIFKVYKW 720


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,755,448
Number of Sequences: 37866
Number of extensions: 1636818
Number of successful extensions: 11919
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 190
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 4271
Number of HSP's gapped (non-prelim): 739
length of query: 884
length of database: 18,247,518
effective HSP length: 111
effective length of query: 773
effective length of database: 14,044,392
effective search space: 10856315016
effective search space used: 10856315016
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.