Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 9966865
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9966865 transient receptor potential cation channel,
subfamily C, member 7 [Homo sapiens]
(862 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9966865 transient receptor potential cation channel, subfamil... 1726 0.0
gi|194733735 transient receptor potential cation channel, subfam... 1363 0.0
gi|4507687 transient receptor potential cation channel, subfamil... 1363 0.0
gi|5730102 transient receptor potential cation channel, subfamil... 1281 0.0
gi|209863024 transient receptor potential cation channel, subfam... 557 e-158
gi|209863026 transient receptor potential cation channel, subfam... 555 e-158
gi|7706747 transient receptor potential cation channel, subfamil... 555 e-158
gi|209863030 transient receptor potential cation channel, subfam... 537 e-152
gi|6912736 transient receptor potential cation channel, subfamil... 536 e-152
gi|209863028 transient receptor potential cation channel, subfam... 451 e-126
gi|4507685 transient receptor potential cation channel, subfamil... 414 e-115
gi|169216484 PREDICTED: similar to transient receptor potential ... 389 e-108
gi|209863032 transient receptor potential cation channel, subfam... 347 2e-95
gi|239754785 PREDICTED: similar to transient receptor potential ... 216 9e-56
gi|239749299 PREDICTED: similar to transient receptor potential ... 216 9e-56
gi|239743393 PREDICTED: hypothetical protein XP_002342847, parti... 216 9e-56
gi|239509090 PREDICTED: similar to transient receptor potential ... 216 9e-56
gi|4507689 transient receptor potential cation channel, subfamil... 80 8e-15
gi|109689695 transient receptor potential cation channel, subfam... 62 2e-09
gi|94538366 transient receptor potential cation channel, subfami... 61 4e-09
gi|148612863 transient receptor potential cation channel, subfam... 61 5e-09
gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens] 59 1e-08
gi|18921093 transient receptor potential cation channel, subfami... 58 4e-08
gi|154091312 transient receptor potential cation channel, subfam... 57 7e-08
gi|154091308 transient receptor potential cation channel, subfam... 57 7e-08
gi|154091310 transient receptor potential cation channel, subfam... 57 7e-08
gi|154091320 transient receptor potential cation channel, subfam... 57 7e-08
gi|154091318 transient receptor potential cation channel, subfam... 57 7e-08
gi|154091316 transient receptor potential cation channel, subfam... 57 7e-08
gi|154091314 transient receptor potential cation channel, subfam... 57 7e-08
>gi|9966865 transient receptor potential cation channel, subfamily
C, member 7 [Homo sapiens]
Length = 862
Score = 1726 bits (4470), Expect = 0.0
Identities = 862/862 (100%), Positives = 862/862 (100%)
Query: 1 MLRNSTFKNMQRRHTTLREKGRRQAIRGPAYMFNEKGTSLTPEEERFLDSAEYGNIPVVR 60
MLRNSTFKNMQRRHTTLREKGRRQAIRGPAYMFNEKGTSLTPEEERFLDSAEYGNIPVVR
Sbjct: 1 MLRNSTFKNMQRRHTTLREKGRRQAIRGPAYMFNEKGTSLTPEEERFLDSAEYGNIPVVR 60
Query: 61 KMLEESKTLNFNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVR 120
KMLEESKTLNFNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVR
Sbjct: 61 KMLEESKTLNFNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVR 120
Query: 121 IVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIV 180
IVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIV
Sbjct: 121 IVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIV 180
Query: 181 HILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVL 240
HILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVL
Sbjct: 181 HILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVL 240
Query: 241 TALELSNELARLANIETEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAILNGDVNFQVW 300
TALELSNELARLANIETEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAILNGDVNFQVW
Sbjct: 241 TALELSNELARLANIETEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAILNGDVNFQVW 300
Query: 301 SDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSI 360
SDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSI
Sbjct: 301 SDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSI 360
Query: 361 GLPFLAIAYWIAPCSKLGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNET 420
GLPFLAIAYWIAPCSKLGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNET
Sbjct: 361 GLPFLAIAYWIAPCSKLGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNET 420
Query: 421 FTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLS 480
FTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLS
Sbjct: 421 FTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLS 480
Query: 481 IFVASFTARFMAFLKATEAQLYVDQHVQDDTLHNVSLPPEVAYFTYARDKWWPSDPQIIS 540
IFVASFTARFMAFLKATEAQLYVDQHVQDDTLHNVSLPPEVAYFTYARDKWWPSDPQIIS
Sbjct: 481 IFVASFTARFMAFLKATEAQLYVDQHVQDDTLHNVSLPPEVAYFTYARDKWWPSDPQIIS 540
Query: 541 EGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNL 600
EGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNL
Sbjct: 541 EGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNL 600
Query: 601 YSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTM 660
YSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTM
Sbjct: 601 YSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTM 660
Query: 661 VVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYY 720
VVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYY
Sbjct: 661 VVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYY 720
Query: 721 LIMRIKMCLIKLCKSKAKSCENDLEMGMLNSKFKKTRYQAGMRNSENLTANNTLSKPTRY 780
LIMRIKMCLIKLCKSKAKSCENDLEMGMLNSKFKKTRYQAGMRNSENLTANNTLSKPTRY
Sbjct: 721 LIMRIKMCLIKLCKSKAKSCENDLEMGMLNSKFKKTRYQAGMRNSENLTANNTLSKPTRY 780
Query: 781 QKIMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLEEKSQATGELADLIQQ 840
QKIMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLEEKSQATGELADLIQQ
Sbjct: 781 QKIMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLEEKSQATGELADLIQQ 840
Query: 841 LSEKFGKNLNKDHLRVNKGKDI 862
LSEKFGKNLNKDHLRVNKGKDI
Sbjct: 841 LSEKFGKNLNKDHLRVNKGKDI 862
>gi|194733735 transient receptor potential cation channel, subfamily
C, member 3 isoform a [Homo sapiens]
Length = 921
Score = 1363 bits (3529), Expect = 0.0
Identities = 682/841 (81%), Positives = 754/841 (89%), Gaps = 7/841 (0%)
Query: 12 RRHTTLREKGRRQAIRGPAYMFNEKGTSLTPEEERFLDSAEYGNIPVVRKMLEESKTLNF 71
RR T +REKGRRQA+RGPA+MFN++GTSLT EEERFLD+AEYGNIPVVRKMLEESKTLN
Sbjct: 81 RRMTVMREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNV 140
Query: 72 NCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVRIVEAILNHPAF 131
NCVDYMGQNALQLAVGNEHLEVTELLLKKENLAR+GDALLLAISKGYVRIVEAILNHP F
Sbjct: 141 NCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGF 200
Query: 132 AQGQRLTLSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIE 191
A +RLTLSP EQEL+DDDFYAYDEDGTRFS DITPIILAAHCQ+YE+VH+LL+KGARIE
Sbjct: 201 AASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIE 260
Query: 192 RPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELAR 251
RPHDYFCKC +C EKQR DSFSHSRSR+NAYKGLAS AYLSLSSEDPVLTALELSNELA+
Sbjct: 261 RPHDYFCKCGDCMEKQRHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAK 320
Query: 252 LANIETEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAILNGDVNFQ--VWSDHHRPSLS 309
LANIE EFKNDYRKLSMQCKDFVVGVLDLCRD+EEVEAILNGD+ + H+ SLS
Sbjct: 321 LANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLESAEPLEVHRHKASLS 380
Query: 310 RIKLAIKYEVKKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAY 369
R+KLAIKYEVKKFVAHPNCQQQLLT+WYENLSGLR+Q+IA+K L V V++GLPFLAI Y
Sbjct: 381 RVKLAIKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGY 440
Query: 370 WIAPCSKLGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFTDYPKQIF 429
WIAPCS+LG+ LRSPFMKFVAHA SF IFLGLLV NASDRFEG+ TLPN T TDYPKQIF
Sbjct: 441 WIAPCSRLGKILRSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIF 500
Query: 430 RVKTTQFSWTEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTAR 489
RVKTTQF+WTEMLIM WVLGM+WSECKE+W EGPREY+L LWN+LDFGMLSIF+A+FTAR
Sbjct: 501 RVKTTQFTWTEMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTAR 560
Query: 490 FMAFLKATEAQLYVDQHVQDDTLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVV 549
F+AFL+AT+AQ YVD +VQ+ L V+LPPE+ YFTYARDKW PSDPQIISEGLYAIAVV
Sbjct: 561 FLAFLQATKAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVV 620
Query: 550 LSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKY 609
LSFSRIAYILPANESFGPLQISLGRTVKDIFKFMV+FIMVF AFMIGMF LYSYY GAK
Sbjct: 621 LSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKV 680
Query: 610 NPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLI 669
N AFTTVEESFKTLFWSIFGLSEV SVVLKYDHKFIENIGYVLYG+YNVTMVVVLLNMLI
Sbjct: 681 NAAFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLI 740
Query: 670 AMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCL 729
AMIN+SYQEIE+D+DVEWKFAR+KLWLSYFD+G+TLP PF+LVPSPKSF Y IMRI
Sbjct: 741 AMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRI---- 796
Query: 730 IKLCKSKAKSCENDLEMGMLNSKFKKTRY-QAGMRNSENLTANNTLSKPTRYQKIMKRLI 788
+ K + + + D+EMGM NSK + + Q+ R E+ + N+ L++PTRYQ+IMKRLI
Sbjct: 797 VNFPKCRRRRLQKDIEMGMGNSKSRLNLFTQSNSRVFESHSFNSILNQPTRYQQIMKRLI 856
Query: 789 KRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLEEKSQATGELADLIQQLSEKFGKN 848
KRYVLKAQVD+ENDEVNEGELKEIKQDISSLRYELLE+KSQAT ELA LI +LSEK +
Sbjct: 857 KRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKLNPS 916
Query: 849 L 849
+
Sbjct: 917 M 917
>gi|4507687 transient receptor potential cation channel, subfamily
C, member 3 isoform b [Homo sapiens]
Length = 848
Score = 1363 bits (3529), Expect = 0.0
Identities = 682/841 (81%), Positives = 754/841 (89%), Gaps = 7/841 (0%)
Query: 12 RRHTTLREKGRRQAIRGPAYMFNEKGTSLTPEEERFLDSAEYGNIPVVRKMLEESKTLNF 71
RR T +REKGRRQA+RGPA+MFN++GTSLT EEERFLD+AEYGNIPVVRKMLEESKTLN
Sbjct: 8 RRMTVMREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNV 67
Query: 72 NCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVRIVEAILNHPAF 131
NCVDYMGQNALQLAVGNEHLEVTELLLKKENLAR+GDALLLAISKGYVRIVEAILNHP F
Sbjct: 68 NCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGF 127
Query: 132 AQGQRLTLSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIE 191
A +RLTLSP EQEL+DDDFYAYDEDGTRFS DITPIILAAHCQ+YE+VH+LL+KGARIE
Sbjct: 128 AASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIE 187
Query: 192 RPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELAR 251
RPHDYFCKC +C EKQR DSFSHSRSR+NAYKGLAS AYLSLSSEDPVLTALELSNELA+
Sbjct: 188 RPHDYFCKCGDCMEKQRHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAK 247
Query: 252 LANIETEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAILNGDVNFQ--VWSDHHRPSLS 309
LANIE EFKNDYRKLSMQCKDFVVGVLDLCRD+EEVEAILNGD+ + H+ SLS
Sbjct: 248 LANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLESAEPLEVHRHKASLS 307
Query: 310 RIKLAIKYEVKKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAY 369
R+KLAIKYEVKKFVAHPNCQQQLLT+WYENLSGLR+Q+IA+K L V V++GLPFLAI Y
Sbjct: 308 RVKLAIKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGY 367
Query: 370 WIAPCSKLGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFTDYPKQIF 429
WIAPCS+LG+ LRSPFMKFVAHA SF IFLGLLV NASDRFEG+ TLPN T TDYPKQIF
Sbjct: 368 WIAPCSRLGKILRSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIF 427
Query: 430 RVKTTQFSWTEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTAR 489
RVKTTQF+WTEMLIM WVLGM+WSECKE+W EGPREY+L LWN+LDFGMLSIF+A+FTAR
Sbjct: 428 RVKTTQFTWTEMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTAR 487
Query: 490 FMAFLKATEAQLYVDQHVQDDTLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVV 549
F+AFL+AT+AQ YVD +VQ+ L V+LPPE+ YFTYARDKW PSDPQIISEGLYAIAVV
Sbjct: 488 FLAFLQATKAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVV 547
Query: 550 LSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKY 609
LSFSRIAYILPANESFGPLQISLGRTVKDIFKFMV+FIMVF AFMIGMF LYSYY GAK
Sbjct: 548 LSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKV 607
Query: 610 NPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLI 669
N AFTTVEESFKTLFWSIFGLSEV SVVLKYDHKFIENIGYVLYG+YNVTMVVVLLNMLI
Sbjct: 608 NAAFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLI 667
Query: 670 AMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCL 729
AMIN+SYQEIE+D+DVEWKFAR+KLWLSYFD+G+TLP PF+LVPSPKSF Y IMRI
Sbjct: 668 AMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRI---- 723
Query: 730 IKLCKSKAKSCENDLEMGMLNSKFKKTRY-QAGMRNSENLTANNTLSKPTRYQKIMKRLI 788
+ K + + + D+EMGM NSK + + Q+ R E+ + N+ L++PTRYQ+IMKRLI
Sbjct: 724 VNFPKCRRRRLQKDIEMGMGNSKSRLNLFTQSNSRVFESHSFNSILNQPTRYQQIMKRLI 783
Query: 789 KRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLEEKSQATGELADLIQQLSEKFGKN 848
KRYVLKAQVD+ENDEVNEGELKEIKQDISSLRYELLE+KSQAT ELA LI +LSEK +
Sbjct: 784 KRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKLNPS 843
Query: 849 L 849
+
Sbjct: 844 M 844
>gi|5730102 transient receptor potential cation channel, subfamily
C, member 6 [Homo sapiens]
Length = 931
Score = 1281 bits (3315), Expect = 0.0
Identities = 644/870 (74%), Positives = 732/870 (84%), Gaps = 20/870 (2%)
Query: 3 RNSTFKNMQRRHTTLREKGRRQAIRGPAYMFNEKGTSLTPEEERFLDSAEYGNIPVVRKM 62
R S + RR T LREKGRR A RGPAYMF+++ TSL+ EEERFLD+AEYGNIPVVRKM
Sbjct: 58 RGSDNRLAHRRQTVLREKGRRLANRGPAYMFSDRSTSLSIEEERFLDAAEYGNIPVVRKM 117
Query: 63 LEESKTLNFNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVRIV 122
LEE +LN NCVDYMGQNALQLAV NEHLE+TELLLKKENL+RVGDALLLAISKGYVRIV
Sbjct: 118 LEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGDALLLAISKGYVRIV 177
Query: 123 EAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIVHI 182
EAIL+HPAFA+G+RL SP + EL+ DDFYAYDEDGTRFSHD+TPIILAAHCQEYEIVH
Sbjct: 178 EAILSHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHT 237
Query: 183 LLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVLTA 242
LL KGARIERPHDYFCKCN+C +KQ+ DSFSHSRSR+NAYKGLAS AYLSLSSEDPV+TA
Sbjct: 238 LLRKGARIERPHDYFCKCNDCNQKQKHDSFSHSRSRINAYKGLASPAYLSLSSEDPVMTA 297
Query: 243 LELSNELARLANIETEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAILNGDVNFQVWSD 302
LELSNELA LANIE EFKNDY+KLSMQCKDFVVG+LDLCR+TEEVEAILNGDV D
Sbjct: 298 LELSNELAVLANIEKEFKNDYKKLSMQCKDFVVGLLDLCRNTEEVEAILNGDVETLQSGD 357
Query: 303 HHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSIGL 362
H RP+LSR+KLAIKYEVKKFVAHPNCQQQLL++WYENLSGLRQQ++AVKFL V V+IGL
Sbjct: 358 HGRPNLSRLKLAIKYEVKKFVAHPNCQQQLLSIWYENLSGLRQQTMAVKFLVVLAVAIGL 417
Query: 363 PFLAIAYWIAPCSKLGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFT 422
PFLA+ YW APCSK+G+ +R PFMKFVAHA SFTIFLGLLV+NA+DRFEG K LPNET T
Sbjct: 418 PFLALIYWFAPCSKMGKIMRGPFMKFVAHAASFTIFLGLLVMNAADRFEGTKLLPNETST 477
Query: 423 DYPKQIFRVKTTQFSWTEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIF 482
D KQ+FR+KT+ FSW EMLI+ WV+GMIW+ECKEIW +GP+EY+ LWN+LDFGML+IF
Sbjct: 478 DNAKQLFRMKTSCFSWMEMLIISWVIGMIWAECKEIWTQGPKEYLFELWNMLDFGMLAIF 537
Query: 483 VASFTARFMAFLKATEAQLYVDQHVQDDTLHNVSLPPEVAYFTYARDKWWPSDPQIISEG 542
ASF ARFMAF A++AQ +D + L V+L V Y+ AR KW PSDPQIISEG
Sbjct: 538 AASFIARFMAFWHASKAQSIIDANDTLKDLTKVTLGDNVKYYNLARIKWDPSDPQIISEG 597
Query: 543 LYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYS 602
LYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYS
Sbjct: 598 LYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYS 657
Query: 603 YYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVV 662
YY GAK N AFTTVEESFKTLFW+IFGLSEV SVV+ Y+HKFIENIGYVLYGVYNVTMV+
Sbjct: 658 YYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVI 717
Query: 663 VLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLI 722
VLLNMLIAMIN+S+QEIE+DADVEWKFARAKLW SYF+EGRTLP PFNLVPSPKS +YL+
Sbjct: 718 VLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSLFYLL 777
Query: 723 MRIKMCLIKLCKSKAKSCENDLEMGMLN--------------SKFKKTRYQAG------M 762
+++K + +L + K + D EM +N SK + Q G +
Sbjct: 778 LKLKKWISELFQGHKKGFQEDAEMNKINEEKKLGILGSHEDLSKLSLDKKQVGHNKQPSI 837
Query: 763 RNSENLTANNTLSKPTRYQKIMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYE 822
R+SE+ N+ + P +YQKIMKRLIKRYVL+AQ+D+E+DEVNEGELKEIKQDISSLRYE
Sbjct: 838 RSSEDFHLNSFNNPPRQYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDISSLRYE 897
Query: 823 LLEEKSQATGELADLIQQLSEKFGKNLNKD 852
LLEEKSQ T +LA+LI++L EK N++
Sbjct: 898 LLEEKSQNTEDLAELIRELGEKLSMEPNQE 927
>gi|209863024 transient receptor potential cation channel, subfamily
C, member 4 isoform epsilon [Homo sapiens]
Length = 982
Score = 557 bits (1435), Expect = e-158
Identities = 326/804 (40%), Positives = 465/804 (57%), Gaps = 91/804 (11%)
Query: 38 TSLTPEEERFLDSAEYGNIPVVRKMLEESKT---LNFNCVDYMGQNALQLAVGNEHLEVT 94
+ L+P E+ +L++ E G+ V+K LEE++ +N NC+D +G+ AL +A+ NE+LE+
Sbjct: 27 SELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELI 86
Query: 95 ELLLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAY 154
ELLL VGDALL AI K V VE +LNH G++ + P+
Sbjct: 87 ELLLSFN--VYVGDALLHAIRKEVVGAVELLLNHKK-PSGEK-QVPPI----------LL 132
Query: 155 DEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSH 214
D+ + F+ DITPIILAAH YEI+ +L+ KG + RPH+ C C EC DS H
Sbjct: 133 DKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRH 192
Query: 215 SRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFV 274
SRSR+N YK LAS + ++LSSEDP LTA +LS EL L+ +E EFK++Y +LS QCK F
Sbjct: 193 SRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFA 252
Query: 275 VGVLDLCRDTEEVEAILNGDVNFQVWSDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLT 334
+LD R + E+E ILN + + + L+R+KLAIKY K+FVA PNCQQ L +
Sbjct: 253 KDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLAS 312
Query: 335 MWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGRTLRSPFMKFVAHAVS 394
WY+ G R++ AVK + F + + P ++ Y IAP S LG +R PF+KF+ H S
Sbjct: 313 RWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTAS 372
Query: 395 FTIFLGLLVVNAS--DRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIW 452
+ FL LL++ + DR + + P T E +I+ WVLG IW
Sbjct: 373 YLTFLFLLLLASQHIDRSDLNRQGPPPTI-----------------VEWMILPWVLGFIW 415
Query: 453 SECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKATEAQLYVDQHVQDDTL 512
E K++W+ G ++Y+ WNL+DF M S+++A+ + + +AF+K +
Sbjct: 416 GEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYS--------------- 460
Query: 513 HNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISL 572
+L P R+ W P +++E L+AIA + S R+ + AN GPLQISL
Sbjct: 461 ---ALNP--------RESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISL 509
Query: 573 GRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYY-----------RGAKYNPAFTTVEESFK 621
GR + DI KF+ I+ +V +AF G+ LY YY R K N AF+T+ E+ +
Sbjct: 510 GRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQ 569
Query: 622 TLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEE 681
+LFWSIFGL + +K H+F E +G ++G YNV +VVLLNMLIAM+NNSYQ I +
Sbjct: 570 SLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIAD 629
Query: 682 DADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSKAKSCE 741
AD+EWKFAR KLW+SYF+EG TLP PFN++PSPKS +YL IK LCK K +
Sbjct: 630 HADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYL---IKWIWTHLCKKKMR--- 683
Query: 742 NDLEMGMLNSKFKKTRYQAGMRNSENLTANNTLSKPTRYQKIMKRLIKRYVLKAQVDREN 801
+ ++ G+R A+N L + +YQ++M+ L+KRYV D +
Sbjct: 684 ----------RKPESFGTIGVRTQHRRAADN-LRRHHQYQEVMRNLVKRYVAAMIRDAKT 732
Query: 802 DE-VNEGELKEIKQDISSLRYELL 824
+E + E KE+KQDISS R+E+L
Sbjct: 733 EEGLTEENFKELKQDISSFRFEVL 756
>gi|209863026 transient receptor potential cation channel, subfamily
C, member 4 isoform beta [Homo sapiens]
Length = 893
Score = 555 bits (1429), Expect = e-158
Identities = 325/804 (40%), Positives = 465/804 (57%), Gaps = 96/804 (11%)
Query: 38 TSLTPEEERFLDSAEYGNIPVVRKMLEESKT---LNFNCVDYMGQNALQLAVGNEHLEVT 94
+ L+P E+ +L++ E G+ V+K LEE++ +N NC+D +G+ AL +A+ NE+LE+
Sbjct: 27 SELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELI 86
Query: 95 ELLLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAY 154
ELLL VGDALL AI K V VE +LNH G++ + P+
Sbjct: 87 ELLLSFN--VYVGDALLHAIRKEVVGAVELLLNHKK-PSGEK-QVPPI----------LL 132
Query: 155 DEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSH 214
D+ + F+ DITPIILAAH YEI+ +L+ KG + RPH+ C C EC DS H
Sbjct: 133 DKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRH 192
Query: 215 SRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFV 274
SRSR+N YK LAS + ++LSSEDP LTA +LS EL L+ +E EFK++Y +LS QCK F
Sbjct: 193 SRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFA 252
Query: 275 VGVLDLCRDTEEVEAILNGDVNFQVWSDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLT 334
+LD R + E+E ILN + + + L+R+KLAIKY K+FVA PNCQQ L +
Sbjct: 253 KDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLAS 312
Query: 335 MWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGRTLRSPFMKFVAHAVS 394
WY+ G R++ AVK + F + + P ++ Y IAP S LG +R PF+KF+ H S
Sbjct: 313 RWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTAS 372
Query: 395 FTIFLGLLVVNAS--DRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIW 452
+ FL LL++ + DR + + P T E +I+ WVLG IW
Sbjct: 373 YLTFLFLLLLASQHIDRSDLNRQGPPPTI-----------------VEWMILPWVLGFIW 415
Query: 453 SECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKATEAQLYVDQHVQDDTL 512
E K++W+ G ++Y+ WNL+DF M S+++A+ + + +AF+K +
Sbjct: 416 GEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYS--------------- 460
Query: 513 HNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISL 572
+L P R+ W P +++E L+AIA + S R+ + AN GPLQISL
Sbjct: 461 ---ALNP--------RESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISL 509
Query: 573 GRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYY-----------RGAKYNPAFTTVEESFK 621
GR + DI KF+ I+ +V +AF G+ LY YY R K N AF+T+ E+ +
Sbjct: 510 GRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQ 569
Query: 622 TLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEE 681
+LFWSIFGL + +K H+F E +G ++G YNV +VVLLNMLIAM+NNSYQ I +
Sbjct: 570 SLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIAD 629
Query: 682 DADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSKAKSCE 741
AD+EWKFAR KLW+SYF+EG TLP PFN++PSPKS +YL IK LCK K +
Sbjct: 630 HADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYL---IKWIWTHLCKKKMR--- 683
Query: 742 NDLEMGMLNSKFKKTRYQAGMRNSENLTANNTLSKPTRYQKIMKRLIKRYVLKAQVDREN 801
+ ++ G R ++NL ++ +YQ++M+ L+KRYV D +
Sbjct: 684 ----------RKPESFGTIGRRAADNLRRHH------QYQEVMRNLVKRYVAAMIRDAKT 727
Query: 802 DE-VNEGELKEIKQDISSLRYELL 824
+E + E KE+KQDISS R+E+L
Sbjct: 728 EEGLTEENFKELKQDISSFRFEVL 751
>gi|7706747 transient receptor potential cation channel, subfamily
C, member 4 isoform alpha [Homo sapiens]
Length = 977
Score = 555 bits (1429), Expect = e-158
Identities = 325/804 (40%), Positives = 465/804 (57%), Gaps = 96/804 (11%)
Query: 38 TSLTPEEERFLDSAEYGNIPVVRKMLEESKT---LNFNCVDYMGQNALQLAVGNEHLEVT 94
+ L+P E+ +L++ E G+ V+K LEE++ +N NC+D +G+ AL +A+ NE+LE+
Sbjct: 27 SELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELI 86
Query: 95 ELLLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAY 154
ELLL VGDALL AI K V VE +LNH G++ + P+
Sbjct: 87 ELLLSFN--VYVGDALLHAIRKEVVGAVELLLNHKK-PSGEK-QVPPI----------LL 132
Query: 155 DEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSH 214
D+ + F+ DITPIILAAH YEI+ +L+ KG + RPH+ C C EC DS H
Sbjct: 133 DKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRH 192
Query: 215 SRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFV 274
SRSR+N YK LAS + ++LSSEDP LTA +LS EL L+ +E EFK++Y +LS QCK F
Sbjct: 193 SRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFA 252
Query: 275 VGVLDLCRDTEEVEAILNGDVNFQVWSDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLT 334
+LD R + E+E ILN + + + L+R+KLAIKY K+FVA PNCQQ L +
Sbjct: 253 KDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLAS 312
Query: 335 MWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGRTLRSPFMKFVAHAVS 394
WY+ G R++ AVK + F + + P ++ Y IAP S LG +R PF+KF+ H S
Sbjct: 313 RWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTAS 372
Query: 395 FTIFLGLLVVNAS--DRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIW 452
+ FL LL++ + DR + + P T E +I+ WVLG IW
Sbjct: 373 YLTFLFLLLLASQHIDRSDLNRQGPPPTI-----------------VEWMILPWVLGFIW 415
Query: 453 SECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKATEAQLYVDQHVQDDTL 512
E K++W+ G ++Y+ WNL+DF M S+++A+ + + +AF+K +
Sbjct: 416 GEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYS--------------- 460
Query: 513 HNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISL 572
+L P R+ W P +++E L+AIA + S R+ + AN GPLQISL
Sbjct: 461 ---ALNP--------RESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISL 509
Query: 573 GRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYY-----------RGAKYNPAFTTVEESFK 621
GR + DI KF+ I+ +V +AF G+ LY YY R K N AF+T+ E+ +
Sbjct: 510 GRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQ 569
Query: 622 TLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEE 681
+LFWSIFGL + +K H+F E +G ++G YNV +VVLLNMLIAM+NNSYQ I +
Sbjct: 570 SLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIAD 629
Query: 682 DADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSKAKSCE 741
AD+EWKFAR KLW+SYF+EG TLP PFN++PSPKS +YL IK LCK K +
Sbjct: 630 HADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYL---IKWIWTHLCKKKMR--- 683
Query: 742 NDLEMGMLNSKFKKTRYQAGMRNSENLTANNTLSKPTRYQKIMKRLIKRYVLKAQVDREN 801
+ ++ G R ++NL ++ +YQ++M+ L+KRYV D +
Sbjct: 684 ----------RKPESFGTIGRRAADNLRRHH------QYQEVMRNLVKRYVAAMIRDAKT 727
Query: 802 DE-VNEGELKEIKQDISSLRYELL 824
+E + E KE+KQDISS R+E+L
Sbjct: 728 EEGLTEENFKELKQDISSFRFEVL 751
>gi|209863030 transient receptor potential cation channel, subfamily
C, member 4 isoform delta [Homo sapiens]
Length = 836
Score = 537 bits (1383), Expect = e-152
Identities = 314/783 (40%), Positives = 450/783 (57%), Gaps = 95/783 (12%)
Query: 38 TSLTPEEERFLDSAEYGNIPVVRKMLEESKT---LNFNCVDYMGQNALQLAVGNEHLEVT 94
+ L+P E+ +L++ E G+ V+K LEE++ +N NC+D +G+ AL +A+ NE+LE+
Sbjct: 27 SELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELI 86
Query: 95 ELLLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAY 154
ELLL VGDALL AI K V VE +LNH G++ + P+
Sbjct: 87 ELLLSFN--VYVGDALLHAIRKEVVGAVELLLNHKK-PSGEK-QVPPI----------LL 132
Query: 155 DEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSH 214
D+ + F+ DITPIILAAH YEI+ +L+ KG + RPH+ C C EC DS H
Sbjct: 133 DKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRH 192
Query: 215 SRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFV 274
SRSR+N YK LAS + ++LSSEDP LTA +LS EL L+ +E EFK++Y +LS QCK F
Sbjct: 193 SRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFA 252
Query: 275 VGVLDLCRDTEEVEAILNGDVNFQVWSDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLT 334
+LD R + E+E ILN + + + L+R+KLAIKY K+FVA PNCQQ L +
Sbjct: 253 KDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLAS 312
Query: 335 MWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGRTLRSPFMKFVAHAVS 394
WY+ G R++ AVK + F + + P ++ Y IAP S LG +R PF+KF+ H S
Sbjct: 313 RWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTAS 372
Query: 395 FTIFLGLLVVNAS--DRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIW 452
+ FL LL++ + DR + + P T E +I+ WVLG IW
Sbjct: 373 YLTFLFLLLLASQHIDRSDLNRQGPPPTI-----------------VEWMILPWVLGFIW 415
Query: 453 SECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKATEAQLYVDQHVQDDTL 512
E K++W+ G ++Y+ WNL+DF M S+++A+ + + +AF+K +
Sbjct: 416 GEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYS--------------- 460
Query: 513 HNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISL 572
+L P R+ W P +++E L+AIA + S R+ + AN GPLQISL
Sbjct: 461 ---ALNP--------RESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISL 509
Query: 573 GRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYY-----------RGAKYNPAFTTVEESFK 621
GR + DI KF+ I+ +V +AF G+ LY YY R K N AF+T+ E+ +
Sbjct: 510 GRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQ 569
Query: 622 TLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEE 681
+LFWSIFGL + +K H+F E +G ++G YNV +VVLLNMLIAM+NNSYQ I +
Sbjct: 570 SLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIAD 629
Query: 682 DADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSKAKSCE 741
AD+EWKFAR KLW+SYF+EG TLP PFN++PSPKS +YL IK LCK K +
Sbjct: 630 HADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYL---IKWIWTHLCKKKMR--- 683
Query: 742 NDLEMGMLNSKFKKTRYQAGMRNSENLTANNTLSKPTRYQKIMKRLIKRYVLKAQVDREN 801
+ ++ G R ++NL ++ +YQ++M+ L+KRYV D +
Sbjct: 684 ----------RKPESFGTIGRRAADNLRRHH------QYQEVMRNLVKRYVAAMIRDAKT 727
Query: 802 DEV 804
+EV
Sbjct: 728 EEV 730
>gi|6912736 transient receptor potential cation channel, subfamily
C, member 5 [Homo sapiens]
Length = 973
Score = 536 bits (1381), Expect = e-152
Identities = 316/812 (38%), Positives = 456/812 (56%), Gaps = 103/812 (12%)
Query: 38 TSLTPEEERFLDSAEYGNIPVVRKMLEESK---TLNFNCVDYMGQNALQLAVGNEHLEVT 94
T L+ EE+ FL++ E G+ V++ L+E++ +N NC+D +G++AL +A+ NE+LE+
Sbjct: 27 TELSAEEKAFLNAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIM 86
Query: 95 ELLLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAY 154
ELLL VGDALL AI K V VE +L++ + +++ ++ + +
Sbjct: 87 ELLLNHS--VYVGDALLYAIRKEVVGAVELLLSYRRPSGEKQVPTLMMDTQFSE------ 138
Query: 155 DEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSH 214
F+ DITPI+LAAH YEI+ +L+ K I RPH C C EC DS H
Sbjct: 139 ------FTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRH 192
Query: 215 SRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFV 274
SRSR+N YK LAS + ++LSSEDP+LTA L EL L+ +E EFK +Y +LS QCK F
Sbjct: 193 SRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFA 252
Query: 275 VGVLDLCRDTEEVEAILNG-DVNFQVWSDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLL 333
+LD R + E+E ILN D + + L+++K+AIKY K+FVA PNCQQ L
Sbjct: 253 KDLLDQARSSRELEIILNHRDDHSEELDPQKYHDLAKLKVAIKYHQKEFVAQPNCQQLLA 312
Query: 334 TMWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGRTLRSPFMKFVAHAV 393
T+WY+ G R++ VK L + P L+IAY I+P S LG ++ PF+KF+ H
Sbjct: 313 TLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTA 372
Query: 394 SFTIFLGLLVVNASDRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIWS 453
S+ FL +L++ + TD V+ + E +I+ WVLG IW
Sbjct: 373 SYLTFLFMLLLASQHIVR----------TD-----LHVQGPPPTVVEWMILPWVLGFIWG 417
Query: 454 ECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKATEAQLYVDQHVQDDTLH 513
E KE+W+ G EY+ WNL+DF M S+++A+ + + +A++K +
Sbjct: 418 EIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVK-----------------Y 460
Query: 514 NVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLG 573
N S P R++W P +I+E L+AI+ +LS R+ + AN GPLQISLG
Sbjct: 461 NGSRP---------REEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLG 511
Query: 574 RTVKDIFKFMVIFIMVFVAFMIGMFNLYSYY--------------RGAKYNPAFTTVEES 619
R + DI KF+ I+ +V +AF G+ LY YY R K N AF+T+ E+
Sbjct: 512 RMLLDILKFLFIYCLVLLAFANGLNQLYFYYETRAIDEPNNCKGIRCEKQNNAFSTLFET 571
Query: 620 FKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEI 679
++LFWS+FGL + +K H+F E +G ++G YNV +VVLLNMLIAM+NNSYQ I
Sbjct: 572 LQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLI 631
Query: 680 EEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSKAKS 739
+ AD+EWKFAR KLW+SYFDEG TLP PFN++PSPKSF YL
Sbjct: 632 ADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYL------------------ 673
Query: 740 CENDLEMGMLNSKFKKTRYQAGMRNSENLTA-----NNTLSKPTRYQKIMKRLIKRYV-L 793
N+ F R G R NL + ++L + YQ++++ L+KRYV
Sbjct: 674 ------GNWFNNTFCPKRDPDGRRRRRNLRSFTERNADSLIQNQHYQEVIRNLVKRYVAA 727
Query: 794 KAQVDRENDEVNEGELKEIKQDISSLRYELLE 825
+ + ++ + E KE+KQDISS RYE+L+
Sbjct: 728 MIRNSKTHEGLTEENFKELKQDISSFRYEVLD 759
>gi|209863028 transient receptor potential cation channel, subfamily
C, member 4 isoform gamma [Homo sapiens]
Length = 828
Score = 451 bits (1161), Expect = e-126
Identities = 265/662 (40%), Positives = 379/662 (57%), Gaps = 73/662 (11%)
Query: 38 TSLTPEEERFLDSAEYGNIPVVRKMLEESKT---LNFNCVDYMGQNALQLAVGNEHLEVT 94
+ L+P E+ +L++ E G+ V+K LEE++ +N NC+D +G+ AL +A+ NE+LE+
Sbjct: 27 SELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELI 86
Query: 95 ELLLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAY 154
ELLL VGDALL AI K V VE +LNH G++ + P+
Sbjct: 87 ELLLSFN--VYVGDALLHAIRKEVVGAVELLLNHKK-PSGEK-QVPPI----------LL 132
Query: 155 DEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSH 214
D+ + F+ DITPIILAAH YEI+ +L+ KG + RPH+ C C EC DS H
Sbjct: 133 DKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRH 192
Query: 215 SRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFV 274
SRSR+N YK LAS + ++LSSEDP LTA +LS EL L+ +E EFK++Y +LS QCK F
Sbjct: 193 SRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFA 252
Query: 275 VGVLDLCRDTEEVEAILNGDVNFQVWSDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLT 334
+LD R + E+E ILN + + + L+R+KLAIKY K+FVA PNCQQ L +
Sbjct: 253 KDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLAS 312
Query: 335 MWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGRTLRSPFMKFVAHAVS 394
WY+ G R++ AVK + F + + P ++ Y IAP S LG +R PF+KF+ H S
Sbjct: 313 RWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTAS 372
Query: 395 FTIFLGLLVVNAS--DRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIW 452
+ FL LL++ + DR + + P T E +I+ WVLG IW
Sbjct: 373 YLTFLFLLLLASQHIDRSDLNRQGPPPTI-----------------VEWMILPWVLGFIW 415
Query: 453 SECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKATEAQLYVDQHVQDDTL 512
E K++W+ G ++Y+ WNL+DF M S+++A+ + + +AF+K +
Sbjct: 416 GEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYS--------------- 460
Query: 513 HNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISL 572
+L P R+ W P +++E L+AIA + S R+ + AN GPLQISL
Sbjct: 461 ---ALNP--------RESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISL 509
Query: 573 GRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYY-----------RGAKYNPAFTTVEESFK 621
GR + DI KF+ I+ +V +AF G+ LY YY R K N AF+T+ E+ +
Sbjct: 510 GRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQ 569
Query: 622 TLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEE 681
+LFWSIFGL + +K H+F E +G ++G YNV +VVLLNMLIAM+NNSYQ I
Sbjct: 570 SLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIAR 629
Query: 682 DA 683
A
Sbjct: 630 RA 631
Score = 48.9 bits (115), Expect = 2e-05
Identities = 29/69 (42%), Positives = 42/69 (60%), Gaps = 4/69 (5%)
Query: 760 AGMRNSENLTAN---NTLSKPTRYQKIMKRLIKRYVLKAQVDRENDE-VNEGELKEIKQD 815
A M NS L A + L + +YQ++M+ L+KRYV D + +E + E KE+KQD
Sbjct: 618 AMMNNSYQLIARRAADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQD 677
Query: 816 ISSLRYELL 824
ISS R+E+L
Sbjct: 678 ISSFRFEVL 686
>gi|4507685 transient receptor potential cation channel, subfamily
C, member 1 [Homo sapiens]
Length = 759
Score = 414 bits (1063), Expect = e-115
Identities = 265/806 (32%), Positives = 413/806 (51%), Gaps = 132/806 (16%)
Query: 41 TPEEERFLDSAEYGNIPVVRKMLEESKT--LNFNCVDYMGQNALQLAVGNEHLEVTELLL 98
T E+ FL + + G+ +V+K+LEE+ + LN NCVD +G+NA+ + + NE+L++ +LLL
Sbjct: 45 TLNEKLFLLACDKGDYYMVKKILEENSSGDLNINCVDVLGRNAVTITIENENLDILQLLL 104
Query: 99 KKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFYAYDEDG 158
G +++E I N P ++
Sbjct: 105 ----------------DYGCQKLMERIQN-PEYST------------------------- 122
Query: 159 TRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSR 218
+ D+ P+ILAAH YEI+ +LL + + +PH C+C C+ K +KDS HSR R
Sbjct: 123 ---TMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFR 179
Query: 219 MNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKNDYRKLSMQCKDFVVGVL 278
++ Y+ LAS A + L+ EDP+L A ELS +L L+ +E EF+NDY +L+ QCK F +L
Sbjct: 180 LDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLL 239
Query: 279 DLCRDTEEVEAILNGDVNFQVWSD----HHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLT 334
R++ E+E ILN + + R +LSR+KLAIKY K+FV+ NCQQ L T
Sbjct: 240 AQARNSRELEVILNHTSSDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNT 299
Query: 335 MWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGRTLRSPFMKFVAHAVS 394
+W+ +SG R++ K + V V I P L++ Y IAP S+ GR + +PFMKF+ H S
Sbjct: 300 VWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGAS 359
Query: 395 FTIFLGLLVVNASDRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIWSE 454
+ FL LL L + + + K + + L++ W++GMIWS+
Sbjct: 360 YFTFLLLL------------NLYSLVYNEDKKNTMGPALERIDY---LLILWIIGMIWSD 404
Query: 455 CKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKATEAQLYVDQHVQDDTLHN 514
K +W EG +++ N L F M S+++A+F + +A HN
Sbjct: 405 IKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVA--------------------HN 444
Query: 515 VSLPPEVAYFTYARDKWWPS-DPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLG 573
+ +A K W + P +++EGL+A A VLS+ R+ ++ + GPLQIS+G
Sbjct: 445 -------KFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMG 497
Query: 574 RTVKDIFKFMVIFIMVFVAFMIGMFNLY-------------SYYRGAKYNPAFTTVEESF 620
+ ++D KF+ +F++V +F IG+ LY + + N F + +
Sbjct: 498 QMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGIFCEQQSNDTFHSFIGTC 557
Query: 621 KTLFWSIFGLSEVISVVLK--YDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQE 678
LFW IF L+ V V + Y + +G V+ G YNV +V+VL +L+AM++ S+Q
Sbjct: 558 FALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQL 617
Query: 679 IEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSKAK 738
I D EWKFARAKLWLSYFD+ TLP PFN++PSPK+ Y+I + +C +K
Sbjct: 618 IANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYMISSLSKW---ICSHTSK 674
Query: 739 SCENDLEMGMLNSKFKKTRYQAGMRNSENLTANNTLSKPTRYQKIMKRLIKRYVLK-AQV 797
K + Q ++ NL + YQK+M L+ RY+ Q
Sbjct: 675 G---------------KVKRQNSLKEWRNLKQ----KRDENYQKVMCCLVHRYLTSMRQK 715
Query: 798 DRENDEVNEGELKEIKQDISSLRYEL 823
+ D+ L E++QD+S R E+
Sbjct: 716 MQSTDQATVENLNELRQDLSKFRNEI 741
>gi|169216484 PREDICTED: similar to transient receptor potential
channel subfamily C member 6 [Homo sapiens]
Length = 304
Score = 389 bits (1000), Expect = e-108
Identities = 194/278 (69%), Positives = 224/278 (80%)
Query: 449 GMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKATEAQLYVDQHVQ 508
GMIW+ECKEIW +GP+EY+ LWN+LDFGML+I ASF ARF AF A++AQ D
Sbjct: 17 GMIWAECKEIWTQGPKEYLFELWNMLDFGMLAILSASFIARFRAFWHASKAQSITDASDT 76
Query: 509 DDTLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPL 568
L V+L V Y++ AR +W PSDP+++SEGL A+AVVLSFS IA ILPANESFGPL
Sbjct: 77 LKDLTKVTLGDNVKYYSLARREWDPSDPRMVSEGLCAVAVVLSFSGIACILPANESFGPL 136
Query: 569 QISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIF 628
Q+SLG VKDIF+FM+IFIMVFVAFMIGMFNLYSYY K N AFTTVEESFKTLFW+ F
Sbjct: 137 QMSLGGAVKDIFRFMLIFIMVFVAFMIGMFNLYSYYIDVKQNEAFTTVEESFKTLFWATF 196
Query: 629 GLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWK 688
LS V SVV+ Y HKFIENIGYVLYGVY+VTMV+VLLNMLIAMIN+S QEIE+DADVEWK
Sbjct: 197 VLSAVKSVVINYSHKFIENIGYVLYGVYDVTMVIVLLNMLIAMINSSLQEIEDDADVEWK 256
Query: 689 FARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIK 726
FARAKLW S F EGR LP PFNLVP P S + L++++K
Sbjct: 257 FARAKLWFSCFGEGRALPVPFNLVPGPGSLFCLLLKLK 294
>gi|209863032 transient receptor potential cation channel, subfamily
C, member 4 isoform zeta [Homo sapiens]
Length = 804
Score = 347 bits (891), Expect = 2e-95
Identities = 202/519 (38%), Positives = 293/519 (56%), Gaps = 79/519 (15%)
Query: 320 KKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGR 379
K+FVA PNCQQ L + WY+ G R++ AVK + F + + P ++ Y IAP S LG
Sbjct: 125 KQFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGL 184
Query: 380 TLRSPFMKFVAHAVSFTIFLGLLVVNAS--DRFEGVKTLPNETFTDYPKQIFRVKTTQFS 437
+R PF+KF+ H S+ FL LL++ + DR + + P T
Sbjct: 185 FIRKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTI---------------- 228
Query: 438 WTEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKAT 497
E +I+ WVLG IW E K++W+ G ++Y+ WNL+DF M S+++A+ + + +AF+K +
Sbjct: 229 -VEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYS 287
Query: 498 EAQLYVDQHVQDDTLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAY 557
+L P R+ W P +++E L+AIA + S R+
Sbjct: 288 ------------------ALNP--------RESWDMWHPTLVAEALFAIANIFSSLRLIS 321
Query: 558 ILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYY-----------RG 606
+ AN GPLQISLGR + DI KF+ I+ +V +AF G+ LY YY R
Sbjct: 322 LFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRC 381
Query: 607 AKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLN 666
K N AF+T+ E+ ++LFWSIFGL + +K H+F E +G ++G YNV +VVLLN
Sbjct: 382 EKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLN 441
Query: 667 MLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIK 726
MLIAM+NNSYQ I + AD+EWKFAR KLW+SYF+EG TLP PFN++PSPKS +YL IK
Sbjct: 442 MLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYL---IK 498
Query: 727 MCLIKLCKSKAKSCENDLEMGMLNSKFKKTRYQAGMRNSENLTANNTLSKPTRYQKIMKR 786
LCK K + + ++ G R ++NL ++ +YQ++M+
Sbjct: 499 WIWTHLCKKKMR-------------RKPESFGTIGRRAADNLRRHH------QYQEVMRN 539
Query: 787 LIKRYVLKAQVDRENDE-VNEGELKEIKQDISSLRYELL 824
L+KRYV D + +E + E KE+KQDISS R+E+L
Sbjct: 540 LVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVL 578
Score = 75.1 bits (183), Expect = 3e-13
Identities = 46/118 (38%), Positives = 70/118 (59%), Gaps = 5/118 (4%)
Query: 38 TSLTPEEERFLDSAEYGNIPVVRKMLEESKT---LNFNCVDYMGQNALQLAVGNEHLEVT 94
+ L+P E+ +L++ E G+ V+K LEE++ +N NC+D +G+ AL +A+ NE+LE+
Sbjct: 27 SELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELI 86
Query: 95 ELLLKKENLARVGDALLLAISKGYVRIVEAILNHPAFAQGQRLTLSPLEQELRDDDFY 152
ELLL VGDALL AI K V VE +LNH + ++ P Q+L +Y
Sbjct: 87 ELLLSFN--VYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQFVAQPNCQQLLASRWY 142
>gi|239754785 PREDICTED: similar to transient receptor potential
cation channel, subfamily C, member 6, partial [Homo
sapiens]
Length = 182
Score = 216 bits (549), Expect = 9e-56
Identities = 109/165 (66%), Positives = 127/165 (76%)
Query: 453 SECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKATEAQLYVDQHVQDDTL 512
+ECKEIW +GP+EY+ LWN+LDFGML IF A F ARF AF A++AQ +D + L
Sbjct: 3 TECKEIWTQGPKEYLFELWNMLDFGMLVIFTALFIARFRAFWHASKAQSIIDANDTLKDL 62
Query: 513 HNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISL 572
V+L V Y+ AR +W PSDP ++SEGL A+AVVLSFS IA ILPANESFGPLQ SL
Sbjct: 63 TEVTLGDNVKYYNLARREWVPSDPWVVSEGLCAVAVVLSFSGIACILPANESFGPLQTSL 122
Query: 573 GRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVE 617
G VKDIF+FMVIFIMVFVAFMIGMFNLYSYY GAK N AFTT++
Sbjct: 123 GGAVKDIFRFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTLK 167
>gi|239749299 PREDICTED: similar to transient receptor potential
cation channel, subfamily C, member 6, partial [Homo
sapiens]
Length = 182
Score = 216 bits (549), Expect = 9e-56
Identities = 109/165 (66%), Positives = 127/165 (76%)
Query: 453 SECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKATEAQLYVDQHVQDDTL 512
+ECKEIW +GP+EY+ LWN+LDFGML IF A F ARF AF A++AQ +D + L
Sbjct: 3 TECKEIWTQGPKEYLFELWNMLDFGMLVIFTALFIARFRAFWHASKAQSIIDANDTLKDL 62
Query: 513 HNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISL 572
V+L V Y+ AR +W PSDP ++SEGL A+AVVLSFS IA ILPANESFGPLQ SL
Sbjct: 63 TEVTLGDNVKYYNLARREWVPSDPWVVSEGLCAVAVVLSFSGIACILPANESFGPLQTSL 122
Query: 573 GRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVE 617
G VKDIF+FMVIFIMVFVAFMIGMFNLYSYY GAK N AFTT++
Sbjct: 123 GGAVKDIFRFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTLK 167
>gi|239743393 PREDICTED: hypothetical protein XP_002342847, partial
[Homo sapiens]
Length = 182
Score = 216 bits (549), Expect = 9e-56
Identities = 109/165 (66%), Positives = 127/165 (76%)
Query: 453 SECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKATEAQLYVDQHVQDDTL 512
+ECKEIW +GP+EY+ LWN+LDFGML IF A F ARF AF A++AQ +D + L
Sbjct: 3 TECKEIWTQGPKEYLFELWNMLDFGMLVIFTALFIARFRAFWHASKAQSIIDANDTLKDL 62
Query: 513 HNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISL 572
V+L V Y+ AR +W PSDP ++SEGL A+AVVLSFS IA ILPANESFGPLQ SL
Sbjct: 63 TEVTLGDNVKYYNLARREWVPSDPWVVSEGLCAVAVVLSFSGIACILPANESFGPLQTSL 122
Query: 573 GRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVE 617
G VKDIF+FMVIFIMVFVAFMIGMFNLYSYY GAK N AFTT++
Sbjct: 123 GGAVKDIFRFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTLK 167
>gi|239509090 PREDICTED: similar to transient receptor potential
cation channel, subfamily C, member 6, partial [Homo
sapiens]
Length = 182
Score = 216 bits (549), Expect = 9e-56
Identities = 109/165 (66%), Positives = 127/165 (76%)
Query: 453 SECKEIWEEGPREYVLHLWNLLDFGMLSIFVASFTARFMAFLKATEAQLYVDQHVQDDTL 512
+ECKEIW +GP+EY+ LWN+LDFGML IF A F ARF AF A++AQ +D + L
Sbjct: 3 TECKEIWTQGPKEYLFELWNMLDFGMLVIFTALFIARFRAFWHASKAQSIIDANDTLKDL 62
Query: 513 HNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISL 572
V+L V Y+ AR +W PSDP ++SEGL A+AVVLSFS IA ILPANESFGPLQ SL
Sbjct: 63 TEVTLGDNVKYYNLARREWVPSDPWVVSEGLCAVAVVLSFSGIACILPANESFGPLQTSL 122
Query: 573 GRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVE 617
G VKDIF+FMVIFIMVFVAFMIGMFNLYSYY GAK N AFTT++
Sbjct: 123 GGAVKDIFRFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTLK 167
>gi|4507689 transient receptor potential cation channel, subfamily M,
member 2 [Homo sapiens]
Length = 1503
Score = 80.1 bits (196), Expect = 8e-15
Identities = 124/565 (21%), Positives = 217/565 (38%), Gaps = 135/565 (23%)
Query: 228 AAYLSLSSEDPVLTALELSNELARLANIE--TEFKNDYRKLSMQCKDFVVGVLDLC--RD 283
A + S+D + AL S L L+ E T+ + L+ + + +GV C +D
Sbjct: 638 AGIIWAQSQDCIAAALACSKILKELSKEEEDTDSSEEMLALAEEYEHRAIGVFTECYRKD 697
Query: 284 TEEVEAILNGDVNFQVWSDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLTMWYENLS-- 341
E + +L + W + ++LA++ + KFV+H Q L +W+ LS
Sbjct: 698 EERAQKLLTRVS--EAWG-----KTTCLQLALEAKDMKFVSHGGIQAFLTKVWWGQLSVD 750
Query: 342 -GLRQQSIAV-KFLAVFGVSIGLPFLAIAYWIAPCSKLGRTLRSPFMKFVAHAVSFTIFL 399
GL + ++ + F + I + P ++ +P + F + +S+ FL
Sbjct: 751 NGLWRVTLCMLAFPLLLTGLISFREKRLQDVGTPAARARAFFTAPVVVFHLNILSYFAFL 810
Query: 400 GLLVVNASDRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIWSECKEIW 459
L F+ V SW E I W+ ++ E ++++
Sbjct: 811 CLFAYVLMVDFQPVP----------------------SWCECAIYLWLFSLVCEEMRQLF 848
Query: 460 EEGPRE---------YVLHLWNLLDFGMLSIFVASFTARFMAFLKATEAQLYVDQHVQDD 510
+ P E Y WN LD G + +FVA T R + A LY
Sbjct: 849 YD-PDECGLMKKAALYFSDFWNKLDVGAILLFVAGLTCRLIP------ATLY-------- 893
Query: 511 TLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQI 570
P V + ++ +L R+ +I +++ GP I
Sbjct: 894 -------PGRV---------------------ILSLDFILFCLRLMHIFTISKTLGPKII 925
Query: 571 SLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSY--------YRGAKYNPAFTTVEESFKT 622
+ R +KD+F F+ + + V+F + + + +RGA Y+ S+ T
Sbjct: 926 IVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNERRVDWLFRGAVYH--------SYLT 977
Query: 623 LFWSIFGLSEVI---------------------SVVLKYDHKFIENIGYVLYGVYNVTMV 661
+F I G + + S + F E + +L +Y +
Sbjct: 978 IFGQIPGYIDGVNFNPEHCSPNGTDPYKPKCPESDATQQRPAFPEWLTVLLLCLYLLFTN 1037
Query: 662 VVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGR-TLPAPFNLVPSPKSFYY 720
++LLN+LIAM N ++Q+++E D WKF R L Y GR P PF L+ +
Sbjct: 1038 ILLLNLLIAMFNYTFQQVQEHTDQIWKFQRHDLIEEY--HGRPAAPPPFILLS------H 1089
Query: 721 LIMRIKMCLIKLCKSKAKSCENDLE 745
L + IK ++K + K +N LE
Sbjct: 1090 LQLFIKRVVLKTPAKRHKQLKNKLE 1114
>gi|109689695 transient receptor potential cation channel, subfamily
M, member 8 [Homo sapiens]
Length = 1104
Score = 62.4 bits (150), Expect = 2e-09
Identities = 107/527 (20%), Positives = 194/527 (36%), Gaps = 109/527 (20%)
Query: 240 LTALELSNELARLANIETEFK--NDYRKLSMQCKDFVVGVLDLCRDTEE--VEAILNGDV 295
L AL S L LA ++ + + +L+ + + V + C ++E E +L
Sbjct: 589 LAALGASKLLKTLAKVKNDINAAGESEELANEYETRAVELFTECYSSDEDLAEQLL---- 644
Query: 296 NFQVWSDHHRPSLSRIKLAIKYEVKKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAV 355
V+S + ++LA++ + F+A P Q L WY +S + + L +
Sbjct: 645 ---VYSCEAWGGSNCLELAVEATDQHFIAQPGVQNFLSKQWYGEISRDTKNWKIILCLFI 701
Query: 356 FGVSIGLPFLAIAYWIAPCSKLGRTL-------RSPFMKFVAHAVSFTIFLGLLVVNASD 408
+ +G F +++ P K + L SPF+ F + V + FL L
Sbjct: 702 IPL-VGCGF--VSFRKKPVDKHKKLLWYYVAFFTSPFVVFSWNVVFYIAFLLLFAYVLLM 758
Query: 409 RFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIWSECKEIWEEGPREYVL 468
F V P E+++ V + E ++ W Y
Sbjct: 759 DFHSVPHPP----------------------ELVLYSLVFVLFCDEVRQ-WYVNGVNYFT 795
Query: 469 HLWNLLDFGMLSIFVASFTARFMAFLKATEAQLYVDQHVQDDTLHNVSLPPEVAYFTYAR 528
LWN++D L F+A R + + ++ LY + +
Sbjct: 796 DLWNVMDTLGLFYFIAGIVFRLHS---SNKSSLYSGRVI--------------------- 831
Query: 529 DKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIM 588
+ + ++ R+ +I + + GP I L R + D+F F+ +F +
Sbjct: 832 ---------------FCLDYIIFTLRLIHIFTVSRNLGPKIIMLQRMLIDVFFFLFLFAV 876
Query: 589 VFVAFMIGMFNLYSY--------YRGAKYNPAF-------TTVEESFKTLFWSIFGLSEV 633
VAF + + +R Y P + V+ + F +E
Sbjct: 877 WMVAFGVARQGILRQNEQRWRWIFRSVIYEPYLAMFGQVPSDVDGTTYDFAHCTFTGNES 936
Query: 634 ISVVLKYDH----KFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKF 689
+ ++ D +F E I L +Y ++ ++L+N+L+AM + ++E+ D WKF
Sbjct: 937 KPLCVELDEHNLPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGTVQENNDQVWKF 996
Query: 690 ARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSK 736
R L Y +P PF + F Y M +K C CK K
Sbjct: 997 QRYFLVQEYCSR-LNIPFPFIV------FAYFYMVVKKCFKCCCKEK 1036
>gi|94538366 transient receptor potential cation channel, subfamily M,
member 1 [Homo sapiens]
Length = 1603
Score = 61.2 bits (147), Expect = 4e-09
Identities = 47/226 (20%), Positives = 102/226 (45%), Gaps = 32/226 (14%)
Query: 543 LYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYS 602
+Y + ++ + R+ I N+ GP + +G+ + D+ F+VI ++V ++F + +
Sbjct: 930 IYCVDIIFWYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILH 989
Query: 603 YYRGAKYNPAFTTVEESFKTLFWSIFG---LSEVISVVLKYDHKFIENI----------- 648
+ P++ F +W I+G ++ ++ + EN+
Sbjct: 990 ----PEEKPSWKLARNIFYMPYWMIYGEVFADQIDLYAMEINPPCGENLYDEEGKRLPPC 1045
Query: 649 ------GYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEG 702
L Y + ++L+N+LIA+ NN++ E++ ++ WKF R +L +++ D
Sbjct: 1046 IPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDR- 1104
Query: 703 RTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSKAKSCENDLEMGM 748
LP P ++ Y +IMR L C+ K + + + + G+
Sbjct: 1105 PVLPPPMIIL---SHIYIIIMR----LSGRCRKKREGDQEERDRGL 1143
>gi|148612863 transient receptor potential cation channel, subfamily
M, member 7 [Homo sapiens]
Length = 1865
Score = 60.8 bits (146), Expect = 5e-09
Identities = 41/189 (21%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Query: 543 LYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYS 602
+Y + ++ + R+ L N+ GP + +G+ V ++F +VI +V ++F + +
Sbjct: 964 IYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKAILY 1023
Query: 603 YYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENI-------GYVLYGV 655
+ P++T ++ +W IFG + + + I I L V
Sbjct: 1024 PHEA----PSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTWLTPFLQAV 1079
Query: 656 YNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSP 715
Y ++++N+LIA NN Y +++ +++ WK+ R ++Y E LP P ++
Sbjct: 1080 YLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAY-HEKPVLPPPLIILSHI 1138
Query: 716 KSFYYLIMR 724
S + I +
Sbjct: 1139 VSLFCCICK 1147
>gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens]
Length = 805
Score = 59.3 bits (142), Expect = 1e-08
Identities = 58/221 (26%), Positives = 97/221 (43%), Gaps = 35/221 (15%)
Query: 466 YVLHLWNLLDFGMLSIFVASFTARFMAFLKATEAQLYVDQHVQDDTLHNVSLPPEVAYFT 525
Y+ +WN+LD L + + S A + E + + +Q P A F
Sbjct: 381 YLSSIWNILD---LVVILLSIVAVGFHIFRTLEVNRLMGKLLQQ--------PNTYADFE 429
Query: 526 YARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVI 585
+ +W Q + A+ + ++ +I + N++ L +L R KDI F V+
Sbjct: 430 FLA--FW----QTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAVM 483
Query: 586 FIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFI 645
F +VF A+ + L F T E+F T IF +I + +D+ I
Sbjct: 484 FFIVFFAYAQLGYLL------------FGTQVENFSTFIKCIFTQFRII--LGDFDYNAI 529
Query: 646 ENIGYVLYGVYNVTMVV----VLLNMLIAMINNSYQEIEED 682
+N +L Y VT V VLLNM +A+IN++Y E++E+
Sbjct: 530 DNANRILGPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEE 570
>gi|18921093 transient receptor potential cation channel, subfamily M,
member 6 [Homo sapiens]
Length = 2022
Score = 57.8 bits (138), Expect = 4e-08
Identities = 46/219 (21%), Positives = 96/219 (43%), Gaps = 20/219 (9%)
Query: 535 DPQIISEG--LYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVA 592
DP + G +Y I ++ FSR+ N+ GP + + ++F ++I +V ++
Sbjct: 931 DPPFHTAGRLIYCIDIIFWFSRLLDFFAVNQHAGPYVTMIAKMTANMFYIVIIMAIVLLS 990
Query: 593 FMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYV- 651
F + + S K P+++ + +W I+G + + ++
Sbjct: 991 FGVARKAILS----PKEPPSWSLARDIVFEPYWMIYGEVYAGEIDVCSSQPSCPPGSFLT 1046
Query: 652 --LYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPF 709
L VY ++++N+LIA NN Y ++E ++ WK+ R + ++Y E LP P
Sbjct: 1047 PFLQAVYLFVQYIIMVNLLIAFFNNVYLDMESISNNLWKYNRYRYIMTY-HEKPWLPPPL 1105
Query: 710 NLVPSPKSFYYLIMRIKMCLIKLCKSKAKSCENDLEMGM 748
L+ + + L +LC +A + + ++G+
Sbjct: 1106 ----------ILLSHVGLLLRRLCCHRAPHDQEEGDVGL 1134
>gi|154091312 transient receptor potential cation channel, subfamily
M, member 3 isoform b [Homo sapiens]
Length = 1566
Score = 57.0 bits (136), Expect = 7e-08
Identities = 46/198 (23%), Positives = 95/198 (47%), Gaps = 28/198 (14%)
Query: 528 RDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFI 587
+D+ + SD ++I Y + ++ + R+ I N+ GP + +G+ + D+ F++I +
Sbjct: 820 QDQPFRSDGRVI----YCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIML 875
Query: 588 MVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVL--------- 638
+V ++F + + P++ + F +W I+G EV + +
Sbjct: 876 VVLMSFGVARQAILF----PNEEPSWKLAKNIFYMPYWMIYG--EVFADQIDPPCGQNET 929
Query: 639 KYDHKFIEN--------IGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFA 690
+ D K I+ I + Y + ++L+N+LIA+ NN++ E++ ++ WKF
Sbjct: 930 REDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQ 989
Query: 691 RAKLWLSYFDEGRTLPAP 708
R +L ++ F E LP P
Sbjct: 990 RYQLIMT-FHERPVLPPP 1006
Score = 30.0 bits (66), Expect = 9.6
Identities = 19/103 (18%), Positives = 45/103 (43%), Gaps = 1/103 (0%)
Query: 570 ISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFG 629
I LGR + + + ++ + IG L++Y K + + +E + G
Sbjct: 715 IPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME-RWPSTQEWIVISYIFTLG 773
Query: 630 LSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMI 672
+ ++ +++ K ++ + L +NVT ++ +L + MI
Sbjct: 774 IEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMI 816
>gi|154091308 transient receptor potential cation channel, subfamily
M, member 3 isoform f [Homo sapiens]
Length = 1579
Score = 57.0 bits (136), Expect = 7e-08
Identities = 46/198 (23%), Positives = 95/198 (47%), Gaps = 28/198 (14%)
Query: 528 RDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFI 587
+D+ + SD ++I Y + ++ + R+ I N+ GP + +G+ + D+ F++I +
Sbjct: 833 QDQPFRSDGRVI----YCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIML 888
Query: 588 MVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVL--------- 638
+V ++F + + P++ + F +W I+G EV + +
Sbjct: 889 VVLMSFGVARQAILF----PNEEPSWKLAKNIFYMPYWMIYG--EVFADQIDPPCGQNET 942
Query: 639 KYDHKFIEN--------IGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFA 690
+ D K I+ I + Y + ++L+N+LIA+ NN++ E++ ++ WKF
Sbjct: 943 REDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQ 1002
Query: 691 RAKLWLSYFDEGRTLPAP 708
R +L ++ F E LP P
Sbjct: 1003 RYQLIMT-FHERPVLPPP 1019
Score = 30.0 bits (66), Expect = 9.6
Identities = 19/103 (18%), Positives = 45/103 (43%), Gaps = 1/103 (0%)
Query: 570 ISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFG 629
I LGR + + + ++ + IG L++Y K + + +E + G
Sbjct: 728 IPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME-RWPSTQEWIVISYIFTLG 786
Query: 630 LSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMI 672
+ ++ +++ K ++ + L +NVT ++ +L + MI
Sbjct: 787 IEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMI 829
>gi|154091310 transient receptor potential cation channel, subfamily
M, member 3 isoform g [Homo sapiens]
Length = 1569
Score = 57.0 bits (136), Expect = 7e-08
Identities = 46/198 (23%), Positives = 95/198 (47%), Gaps = 28/198 (14%)
Query: 528 RDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFI 587
+D+ + SD ++I Y + ++ + R+ I N+ GP + +G+ + D+ F++I +
Sbjct: 823 QDQPFRSDGRVI----YCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIML 878
Query: 588 MVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVL--------- 638
+V ++F + + P++ + F +W I+G EV + +
Sbjct: 879 VVLMSFGVARQAILF----PNEEPSWKLAKNIFYMPYWMIYG--EVFADQIDPPCGQNET 932
Query: 639 KYDHKFIEN--------IGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFA 690
+ D K I+ I + Y + ++L+N+LIA+ NN++ E++ ++ WKF
Sbjct: 933 REDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQ 992
Query: 691 RAKLWLSYFDEGRTLPAP 708
R +L ++ F E LP P
Sbjct: 993 RYQLIMT-FHERPVLPPP 1009
Score = 30.0 bits (66), Expect = 9.6
Identities = 19/103 (18%), Positives = 45/103 (43%), Gaps = 1/103 (0%)
Query: 570 ISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFG 629
I LGR + + + ++ + IG L++Y K + + +E + G
Sbjct: 718 IPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME-RWPSTQEWIVISYIFTLG 776
Query: 630 LSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMI 672
+ ++ +++ K ++ + L +NVT ++ +L + MI
Sbjct: 777 IEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMI 819
>gi|154091320 transient receptor potential cation channel, subfamily
M, member 3 isoform a [Homo sapiens]
Length = 1554
Score = 57.0 bits (136), Expect = 7e-08
Identities = 46/198 (23%), Positives = 95/198 (47%), Gaps = 28/198 (14%)
Query: 528 RDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFI 587
+D+ + SD ++I Y + ++ + R+ I N+ GP + +G+ + D+ F++I +
Sbjct: 808 QDQPFRSDGRVI----YCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIML 863
Query: 588 MVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVL--------- 638
+V ++F + + P++ + F +W I+G EV + +
Sbjct: 864 VVLMSFGVARQAILF----PNEEPSWKLAKNIFYMPYWMIYG--EVFADQIDPPCGQNET 917
Query: 639 KYDHKFIEN--------IGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFA 690
+ D K I+ I + Y + ++L+N+LIA+ NN++ E++ ++ WKF
Sbjct: 918 REDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQ 977
Query: 691 RAKLWLSYFDEGRTLPAP 708
R +L ++ F E LP P
Sbjct: 978 RYQLIMT-FHERPVLPPP 994
Score = 30.0 bits (66), Expect = 9.6
Identities = 19/103 (18%), Positives = 45/103 (43%), Gaps = 1/103 (0%)
Query: 570 ISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFG 629
I LGR + + + ++ + IG L++Y K + + +E + G
Sbjct: 703 IPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME-RWPSTQEWIVISYIFTLG 761
Query: 630 LSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMI 672
+ ++ +++ K ++ + L +NVT ++ +L + MI
Sbjct: 762 IEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMI 804
>gi|154091318 transient receptor potential cation channel, subfamily
M, member 3 isoform d [Homo sapiens]
Length = 1544
Score = 57.0 bits (136), Expect = 7e-08
Identities = 46/198 (23%), Positives = 95/198 (47%), Gaps = 28/198 (14%)
Query: 528 RDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFI 587
+D+ + SD ++I Y + ++ + R+ I N+ GP + +G+ + D+ F++I +
Sbjct: 798 QDQPFRSDGRVI----YCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIML 853
Query: 588 MVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVL--------- 638
+V ++F + + P++ + F +W I+G EV + +
Sbjct: 854 VVLMSFGVARQAILF----PNEEPSWKLAKNIFYMPYWMIYG--EVFADQIDPPCGQNET 907
Query: 639 KYDHKFIEN--------IGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFA 690
+ D K I+ I + Y + ++L+N+LIA+ NN++ E++ ++ WKF
Sbjct: 908 REDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQ 967
Query: 691 RAKLWLSYFDEGRTLPAP 708
R +L ++ F E LP P
Sbjct: 968 RYQLIMT-FHERPVLPPP 984
Score = 30.0 bits (66), Expect = 9.6
Identities = 19/103 (18%), Positives = 45/103 (43%), Gaps = 1/103 (0%)
Query: 570 ISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFG 629
I LGR + + + ++ + IG L++Y K + + +E + G
Sbjct: 693 IPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME-RWPSTQEWIVISYIFTLG 751
Query: 630 LSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMI 672
+ ++ +++ K ++ + L +NVT ++ +L + MI
Sbjct: 752 IEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMI 794
>gi|154091316 transient receptor potential cation channel, subfamily
M, member 3 isoform e [Homo sapiens]
Length = 1556
Score = 57.0 bits (136), Expect = 7e-08
Identities = 46/198 (23%), Positives = 95/198 (47%), Gaps = 28/198 (14%)
Query: 528 RDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFI 587
+D+ + SD ++I Y + ++ + R+ I N+ GP + +G+ + D+ F++I +
Sbjct: 810 QDQPFRSDGRVI----YCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIML 865
Query: 588 MVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVL--------- 638
+V ++F + + P++ + F +W I+G EV + +
Sbjct: 866 VVLMSFGVARQAILF----PNEEPSWKLAKNIFYMPYWMIYG--EVFADQIDPPCGQNET 919
Query: 639 KYDHKFIEN--------IGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFA 690
+ D K I+ I + Y + ++L+N+LIA+ NN++ E++ ++ WKF
Sbjct: 920 REDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQ 979
Query: 691 RAKLWLSYFDEGRTLPAP 708
R +L ++ F E LP P
Sbjct: 980 RYQLIMT-FHERPVLPPP 996
Score = 30.0 bits (66), Expect = 9.6
Identities = 19/103 (18%), Positives = 45/103 (43%), Gaps = 1/103 (0%)
Query: 570 ISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFG 629
I LGR + + + ++ + IG L++Y K + + +E + G
Sbjct: 705 IPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME-RWPSTQEWIVISYIFTLG 763
Query: 630 LSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMI 672
+ ++ +++ K ++ + L +NVT ++ +L + MI
Sbjct: 764 IEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMI 806
>gi|154091314 transient receptor potential cation channel, subfamily
M, member 3 isoform k [Homo sapiens]
Length = 1707
Score = 57.0 bits (136), Expect = 7e-08
Identities = 46/198 (23%), Positives = 95/198 (47%), Gaps = 28/198 (14%)
Query: 528 RDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFI 587
+D+ + SD ++I Y + ++ + R+ I N+ GP + +G+ + D+ F++I +
Sbjct: 961 QDQPFRSDGRVI----YCVNIIYWYIRLLDIFGVNKYLGPYVMMIGKMMIDMMYFVIIML 1016
Query: 588 MVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVL--------- 638
+V ++F + + P++ + F +W I+G EV + +
Sbjct: 1017 VVLMSFGVARQAILF----PNEEPSWKLAKNIFYMPYWMIYG--EVFADQIDPPCGQNET 1070
Query: 639 KYDHKFIEN--------IGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFA 690
+ D K I+ I + Y + ++L+N+LIA+ NN++ E++ ++ WKF
Sbjct: 1071 REDGKIIQLPPCKTGAWIVPAIMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQ 1130
Query: 691 RAKLWLSYFDEGRTLPAP 708
R +L ++ F E LP P
Sbjct: 1131 RYQLIMT-FHERPVLPPP 1147
Score = 30.0 bits (66), Expect = 9.6
Identities = 19/103 (18%), Positives = 45/103 (43%), Gaps = 1/103 (0%)
Query: 570 ISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFG 629
I LGR + + + ++ + IG L++Y K + + +E + G
Sbjct: 856 IPLGRKIYEFYNAPIVKFWFYTLAYIGYLMLFNYIVLVKME-RWPSTQEWIVISYIFTLG 914
Query: 630 LSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMI 672
+ ++ +++ K ++ + L +NVT ++ +L + MI
Sbjct: 915 IEKMREILMSEPGKLLQKVKVWLQEYWNVTDLIAILLFSVGMI 957
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,722,892
Number of Sequences: 37866
Number of extensions: 1253745
Number of successful extensions: 4286
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 89
Number of HSP's that attempted gapping in prelim test: 3870
Number of HSP's gapped (non-prelim): 403
length of query: 862
length of database: 18,247,518
effective HSP length: 111
effective length of query: 751
effective length of database: 14,044,392
effective search space: 10547338392
effective search space used: 10547338392
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.