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Search of human proteins with 9966783
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9966783 BCL2-like 10 (apoptosis facilitator) [Homo sapiens]
(204 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9966783 BCL2-like 10 (apoptosis facilitator) [Homo sapiens] 422 e-118
gi|4757842 BCL2-like 2 protein [Homo sapiens] 41 6e-04
gi|20631964 BCL2-associated X protein isoform delta [Homo sapiens] 39 0.002
gi|20631958 BCL2-associated X protein isoform alpha [Homo sapiens] 39 0.002
gi|11386165 myeloid cell leukemia sequence 1 isoform 1 [Homo sap... 37 0.015
gi|20336335 BCL2-like 1 isoform 1 [Homo sapiens] 36 0.020
gi|72198189 B-cell lymphoma protein 2 alpha isoform [Homo sapiens] 31 0.64
gi|121582655 ankyrin repeat domain 35 [Homo sapiens] 31 0.64
gi|4757840 BCL2-related protein A1 isoform 1 [Homo sapiens] 30 1.4
gi|116268097 beta-1,3-galactosyltransferase 6 [Homo sapiens] 30 1.9
gi|168480072 BCL2-related protein A1 isoform 2 [Homo sapiens] 29 3.2
gi|4826740 growth differentiation factor 10 precursor [Homo sapi... 28 4.1
gi|19923356 Cdc42 effector protein 3 [Homo sapiens] 28 5.4
gi|157266337 betaine-homocysteine methyltransferase [Homo sapiens] 28 7.1
gi|169213954 PREDICTED: similar to hCG2040171 [Homo sapiens] 27 9.2
gi|239756839 PREDICTED: hypothetical protein [Homo sapiens] 27 9.2
gi|239751793 PREDICTED: similar to hCG2040171 [Homo sapiens] 27 9.2
gi|239751352 PREDICTED: hypothetical protein XP_002347815 [Homo ... 27 9.2
gi|239746284 PREDICTED: similar to hCG2040171 [Homo sapiens] 27 9.2
gi|239745851 PREDICTED: hypothetical protein XP_002343605 [Homo ... 27 9.2
gi|239740933 PREDICTED: hypothetical protein XP_002344111 [Homo ... 27 9.2
gi|29725607 smooth muscle cell associated protein-1 isoform 2 [H... 27 9.2
>gi|9966783 BCL2-like 10 (apoptosis facilitator) [Homo sapiens]
Length = 204
Score = 422 bits (1084), Expect = e-118
Identities = 204/204 (100%), Positives = 204/204 (100%)
Query: 1 MVDQLRERTTMADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIH 60
MVDQLRERTTMADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIH
Sbjct: 1 MVDQLRERTTMADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIH 60
Query: 61 RSFFSAYLGYPGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKK 120
RSFFSAYLGYPGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKK
Sbjct: 61 RSFFSAYLGYPGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKK 120
Query: 121 WGFQPRLKEQEGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWR 180
WGFQPRLKEQEGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWR
Sbjct: 121 WGFQPRLKEQEGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWR 180
Query: 181 KQLVQAFLSCLLTTAFIYLWTRLL 204
KQLVQAFLSCLLTTAFIYLWTRLL
Sbjct: 181 KQLVQAFLSCLLTTAFIYLWTRLL 204
>gi|4757842 BCL2-like 2 protein [Homo sapiens]
Length = 193
Score = 41.2 bits (95), Expect = 6e-04
Identities = 41/158 (25%), Positives = 61/158 (38%), Gaps = 30/158 (18%)
Query: 19 TELLLADYLGYCAREPGT-----PEPAPST-PEAAVLRSAAARLRQIHRSFFSAYLGY-- 70
T L+AD++GY R+ G P P+ P +R+A R FS
Sbjct: 10 TRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLH 69
Query: 71 --PGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLK 128
PG+ + ++D + GP WGR+V F L + K
Sbjct: 70 VTPGSAQQRFTQVSDELFQG--GPNWGRLVAFFVFGAALCA--------------ESVNK 113
Query: 129 EQEGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGF 166
E E V + + +VA L +RL W+ + GGW F
Sbjct: 114 EMEPLVGQVQEWMVAYLETRLAD----WIHSSGGWAEF 147
>gi|20631964 BCL2-associated X protein isoform delta [Homo sapiens]
Length = 143
Score = 39.3 bits (90), Expect = 0.002
Identities = 35/110 (31%), Positives = 47/110 (42%), Gaps = 25/110 (22%)
Query: 94 WGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQH 153
WGRVV L FA L+ + P L D L RL+G
Sbjct: 58 WGRVVALFYFASKLVLKALCTKV--------PELIRTIMGWTLD------FLRERLLG-- 101
Query: 154 RAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSCLLTTAFIYLWTRL 203
W+Q QGGWDG +F TP W Q V F++ +L TA + +W ++
Sbjct: 102 --WIQDQGGWDGLLSYFGTP----TW--QTVTIFVAGVL-TASLTIWKKM 142
>gi|20631958 BCL2-associated X protein isoform alpha [Homo sapiens]
Length = 192
Score = 39.3 bits (90), Expect = 0.002
Identities = 35/110 (31%), Positives = 47/110 (42%), Gaps = 25/110 (22%)
Query: 94 WGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQH 153
WGRVV L FA L+ + P L D L RL+G
Sbjct: 107 WGRVVALFYFASKLVLKALCTKV--------PELIRTIMGWTLD------FLRERLLG-- 150
Query: 154 RAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSCLLTTAFIYLWTRL 203
W+Q QGGWDG +F TP W Q V F++ +L TA + +W ++
Sbjct: 151 --WIQDQGGWDGLLSYFGTP----TW--QTVTIFVAGVL-TASLTIWKKM 191
>gi|11386165 myeloid cell leukemia sequence 1 isoform 1 [Homo
sapiens]
Length = 350
Score = 36.6 bits (83), Expect = 0.015
Identities = 37/146 (25%), Positives = 56/146 (38%), Gaps = 28/146 (19%)
Query: 35 GTPEPAPSTPEAAVLRSAAARLRQI-------HRSFFSAYLGYPG--NRFELVALMADSV 85
G + P A R A LR++ H + F L N ++ +L +
Sbjct: 192 GAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMI 251
Query: 86 LSDSPGPT-WGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVAL 144
S G T WGR+VTL++F + + + QE + + L
Sbjct: 252 HVFSDGVTNWGRIVTLISFGAFVAKHLKTIN--------------QESCI----EPLAES 293
Query: 145 LSSRLMGQHRAWLQAQGGWDGFCHFF 170
++ L+ R WL Q GWDGF FF
Sbjct: 294 ITDVLVRTKRDWLVKQRGWDGFVEFF 319
>gi|20336335 BCL2-like 1 isoform 1 [Homo sapiens]
Length = 233
Score = 36.2 bits (82), Expect = 0.020
Identities = 31/134 (23%), Positives = 50/134 (37%), Gaps = 27/134 (20%)
Query: 44 PEAAV---LRSAAARLRQIHRSFFSAYLGY----PGNRFELVALMADSVLSDSPGPTWGR 96
P AAV LR A +R FS PG ++ + + + D G WGR
Sbjct: 82 PMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRD--GVNWGR 139
Query: 97 VVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQHRAW 156
+V +F G L ++ + ++ R+ A +++ L W
Sbjct: 140 IVAFFSFGGALC------------------VESVDKEMQVLVSRIAAWMATYLNDHLEPW 181
Query: 157 LQAQGGWDGFCHFF 170
+Q GGWD F +
Sbjct: 182 IQENGGWDTFVELY 195
>gi|72198189 B-cell lymphoma protein 2 alpha isoform [Homo sapiens]
Length = 239
Score = 31.2 bits (69), Expect = 0.64
Identities = 39/158 (24%), Positives = 56/158 (35%), Gaps = 43/158 (27%)
Query: 50 RSAAARLRQIHRSFFSAYLGYPGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLL- 108
R A Q+H + F+A RF A + + + D G WGR+V F G +
Sbjct: 110 RDFAEMSSQLHLTPFTAR-----GRF---ATVVEELFRD--GVNWGRIVAFFEFGGVMCV 159
Query: 109 -----ERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQH-RAWLQAQGG 162
E PLV +AL + + +H W+Q GG
Sbjct: 160 ESVNREMSPLVDN-------------------------IALWMTEYLNRHLHTWIQDNGG 194
Query: 163 WDGFCHFFRTPF-PLAFWRKQLVQAFLSCLLTTAFIYL 199
WD F + PL + ++ LS L A I L
Sbjct: 195 WDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITL 232
>gi|121582655 ankyrin repeat domain 35 [Homo sapiens]
Length = 1001
Score = 31.2 bits (69), Expect = 0.64
Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 1 MVDQLRERTTMADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQ 58
+VD+ RE + L+E + L L C REPGT AP++P+ A L +L +
Sbjct: 736 LVDRHREAQQVLARLQEENQQLRGS-LSPC-REPGTSLKAPASPQVAALEQDLGKLEE 791
>gi|4757840 BCL2-related protein A1 isoform 1 [Homo sapiens]
Length = 175
Score = 30.0 bits (66), Expect = 1.4
Identities = 18/78 (23%), Positives = 33/78 (42%), Gaps = 16/78 (20%)
Query: 94 WGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQH 153
WGR+VT+ F G L+++ L++Q + + ++ +M
Sbjct: 86 WGRIVTIFAFEGILIKK---------------LLRQQIAPDVDTYKEISYFVAEFIMNNT 130
Query: 154 RAWLQAQGGWD-GFCHFF 170
W++ GGW+ GF F
Sbjct: 131 GEWIRQNGGWENGFVKKF 148
>gi|116268097 beta-1,3-galactosyltransferase 6 [Homo sapiens]
Length = 329
Score = 29.6 bits (65), Expect = 1.9
Identities = 24/62 (38%), Positives = 30/62 (48%), Gaps = 14/62 (22%)
Query: 26 YLGYCAREPGTPE---------PAPSTPEA--AVLRSAAARL---RQIHRSFFSAYLGYP 71
YL CA EPG P PAP+ A AVL ++A R R + RS + A G P
Sbjct: 28 YLARCAAEPGDPRAMSGRSPPPPAPARAAAFLAVLVASAPRAAERRSVIRSTWLARRGAP 87
Query: 72 GN 73
G+
Sbjct: 88 GD 89
>gi|168480072 BCL2-related protein A1 isoform 2 [Homo sapiens]
Length = 163
Score = 28.9 bits (63), Expect = 3.2
Identities = 15/70 (21%), Positives = 29/70 (41%), Gaps = 15/70 (21%)
Query: 94 WGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQH 153
WGR+VT+ F G L+++ L++Q + + ++ +M
Sbjct: 86 WGRIVTIFAFEGILIKK---------------LLRQQIAPDVDTYKEISYFVAEFIMNNT 130
Query: 154 RAWLQAQGGW 163
W++ GGW
Sbjct: 131 GEWIRQNGGW 140
>gi|4826740 growth differentiation factor 10 precursor [Homo
sapiens]
Length = 478
Score = 28.5 bits (62), Expect = 4.1
Identities = 14/41 (34%), Positives = 21/41 (51%)
Query: 4 QLRERTTMADPLRERTELLLADYLGYCAREPGTPEPAPSTP 44
Q ++ + + R ELLL+ L R+PG P P+P P
Sbjct: 202 QAKDISPIVKAARRDGELLLSAQLDSEERDPGVPRPSPYAP 242
>gi|19923356 Cdc42 effector protein 3 [Homo sapiens]
Length = 254
Score = 28.1 bits (61), Expect = 5.4
Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 5/65 (7%)
Query: 66 AYLG-YPG-NRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPL---VTARWKK 120
A+LG +PG N F +DSV +++P P ++L T G+ PL VT K+
Sbjct: 73 AHLGQFPGHNEFFRANSTSDSVFTETPSPVLKNAISLPTIGGSQALMLPLLSPVTFNSKQ 132
Query: 121 WGFQP 125
F P
Sbjct: 133 ESFGP 137
>gi|157266337 betaine-homocysteine methyltransferase [Homo
sapiens]
Length = 406
Score = 27.7 bits (60), Expect = 7.1
Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 9/39 (23%)
Query: 28 GYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSA 66
GY P TPE A PEA +RQ+HR F A
Sbjct: 37 GYVKAGPWTPEAAVEHPEA---------VRQLHREFLRA 66
>gi|169213954 PREDICTED: similar to hCG2040171 [Homo sapiens]
Length = 354
Score = 27.3 bits (59), Expect = 9.2
Identities = 31/95 (32%), Positives = 36/95 (37%), Gaps = 16/95 (16%)
Query: 34 PGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGYPGNRFELVALMADSVLSDSPGPT 93
PG P+ P TPE +A RL G PG R L D + DSP P
Sbjct: 156 PG-PDAPPLTPETLQTLFSAPRL------------GEPGARTPLFTSETDKLRLDSPFPF 202
Query: 94 WGRVVTLVTFAGTLLERGPLVTARWK-KWGFQPRL 127
G T + LL GP A + W F P L
Sbjct: 203 LGSGATSYSKPPGLL--GPYGRAFPEYPWNFNPYL 235
>gi|239756839 PREDICTED: hypothetical protein [Homo sapiens]
Length = 743
Score = 27.3 bits (59), Expect = 9.2
Identities = 13/25 (52%), Positives = 16/25 (64%)
Query: 32 REPGTPEPAPSTPEAAVLRSAAARL 56
R GTP PA TP A V R++ AR+
Sbjct: 206 RPAGTPMPAALTPAAHVPRASTARM 230
>gi|239751793 PREDICTED: similar to hCG2040171 [Homo sapiens]
Length = 354
Score = 27.3 bits (59), Expect = 9.2
Identities = 31/95 (32%), Positives = 36/95 (37%), Gaps = 16/95 (16%)
Query: 34 PGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGYPGNRFELVALMADSVLSDSPGPT 93
PG P+ P TPE +A RL G PG R L D + DSP P
Sbjct: 156 PG-PDAPPLTPETLQTLFSAPRL------------GEPGARTPLFTSETDKLRLDSPFPF 202
Query: 94 WGRVVTLVTFAGTLLERGPLVTARWK-KWGFQPRL 127
G T + LL GP A + W F P L
Sbjct: 203 LGSGATSYSKPPGLL--GPYGRAFPEYPWNFNPYL 235
>gi|239751352 PREDICTED: hypothetical protein XP_002347815 [Homo
sapiens]
Length = 697
Score = 27.3 bits (59), Expect = 9.2
Identities = 13/25 (52%), Positives = 16/25 (64%)
Query: 32 REPGTPEPAPSTPEAAVLRSAAARL 56
R GTP PA TP A V R++ AR+
Sbjct: 206 RPAGTPMPAALTPAAHVPRASTARM 230
>gi|239746284 PREDICTED: similar to hCG2040171 [Homo sapiens]
Length = 354
Score = 27.3 bits (59), Expect = 9.2
Identities = 31/95 (32%), Positives = 36/95 (37%), Gaps = 16/95 (16%)
Query: 34 PGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGYPGNRFELVALMADSVLSDSPGPT 93
PG P+ P TPE +A RL G PG R L D + DSP P
Sbjct: 156 PG-PDAPPLTPETLQTLFSAPRL------------GEPGARTPLFTSETDKLRLDSPFPF 202
Query: 94 WGRVVTLVTFAGTLLERGPLVTARWK-KWGFQPRL 127
G T + LL GP A + W F P L
Sbjct: 203 LGSGATSYSKPPGLL--GPYGRAFPEYPWNFNPYL 235
>gi|239745851 PREDICTED: hypothetical protein XP_002343605 [Homo
sapiens]
Length = 500
Score = 27.3 bits (59), Expect = 9.2
Identities = 13/25 (52%), Positives = 16/25 (64%)
Query: 32 REPGTPEPAPSTPEAAVLRSAAARL 56
R GTP PA TP A V R++ AR+
Sbjct: 206 RPAGTPMPAALTPAAHVPRASTARM 230
>gi|239740933 PREDICTED: hypothetical protein XP_002344111 [Homo
sapiens]
Length = 697
Score = 27.3 bits (59), Expect = 9.2
Identities = 13/25 (52%), Positives = 16/25 (64%)
Query: 32 REPGTPEPAPSTPEAAVLRSAAARL 56
R GTP PA TP A V R++ AR+
Sbjct: 206 RPAGTPMPAALTPAAHVPRASTARM 230
>gi|29725607 smooth muscle cell associated protein-1 isoform 2
[Homo sapiens]
Length = 944
Score = 27.3 bits (59), Expect = 9.2
Identities = 10/14 (71%), Positives = 12/14 (85%)
Query: 34 PGTPEPAPSTPEAA 47
PGTPEP P+TP A+
Sbjct: 6 PGTPEPRPATPGAS 19
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.138 0.451
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,636,571
Number of Sequences: 37866
Number of extensions: 387052
Number of successful extensions: 1741
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1718
Number of HSP's gapped (non-prelim): 29
length of query: 204
length of database: 18,247,518
effective HSP length: 97
effective length of query: 107
effective length of database: 14,574,516
effective search space: 1559473212
effective search space used: 1559473212
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.