Guide to the Human Genome
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Search of human proteins with 9951927

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9951927 adducin 3 (gamma) isoform b [Homo sapiens]
         (674 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9951927 adducin 3 (gamma) isoform b [Homo sapiens]                1351   0.0  
gi|62912453 adducin 3 (gamma) isoform b [Homo sapiens]               1351   0.0  
gi|9943848 adducin 3 (gamma) isoform a [Homo sapiens]                1334   0.0  
gi|9257192 adducin 2 isoform a [Homo sapiens]                         740   0.0  
gi|9257190 adducin 2 isoform e [Homo sapiens]                         687   0.0  
gi|29826319 adducin 1 (alpha) isoform a [Homo sapiens]                672   0.0  
gi|29826323 adducin 1 (alpha) isoform c [Homo sapiens]                660   0.0  
gi|89276787 adducin 2 isoform b [Homo sapiens]                        657   0.0  
gi|29826321 adducin 1 (alpha) isoform b [Homo sapiens]                656   0.0  
gi|29826325 adducin 1 (alpha) isoform d [Homo sapiens]                645   0.0  
gi|89276790 adducin 2 isoform d [Homo sapiens]                        222   8e-58
gi|9257180 adducin 2 isoform c [Homo sapiens]                         222   8e-58
gi|56676397 ankyrin repeat domain 11 [Homo sapiens]                    40   0.007
gi|206597543 hypothetical protein LOC118461 isoform 1 [Homo sapi...    37   0.059
gi|166235186 APAF1 interacting protein [Homo sapiens]                  36   0.10 
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]    36   0.13 
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     35   0.30 
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    34   0.50 
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    34   0.50 
gi|110349719 titin isoform N2-A [Homo sapiens]                         33   0.66 
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]        33   0.86 
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    32   1.9  
gi|40255052 IQ motif containing with AAA domain 1 [Homo sapiens]       32   1.9  
gi|221219020 NYD-SP11 protein [Homo sapiens]                           32   2.5  
gi|117190342 PHD finger protein 2 [Homo sapiens]                       32   2.5  
gi|19923599 calmin [Homo sapiens]                                      32   2.5  
gi|150418007 RAN binding protein 2 [Homo sapiens]                      31   3.3  
gi|27894339 keratin 23 [Homo sapiens]                                  31   3.3  
gi|5031873 lectin, mannose-binding, 1 precursor [Homo sapiens]         31   3.3  
gi|117968420 NUF2, NDC80 kinetochore complex component [Homo sap...    31   3.3  

>gi|9951927 adducin 3 (gamma) isoform b [Homo sapiens]
          Length = 674

 Score = 1351 bits (3496), Expect = 0.0
 Identities = 674/674 (100%), Positives = 674/674 (100%)

Query: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60
           MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ
Sbjct: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60

Query: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPIN 120
           ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPIN
Sbjct: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPIN 120

Query: 121 DLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLS 180
           DLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLS
Sbjct: 121 DLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLS 180

Query: 181 FSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAV 240
           FSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAV
Sbjct: 181 FSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAV 240

Query: 241 SSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALG 300
           SSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALG
Sbjct: 241 SSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALG 300

Query: 301 ETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGS 360
           ETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGS
Sbjct: 301 ETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGS 360

Query: 361 HQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTV 420
           HQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTV
Sbjct: 361 HQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTV 420

Query: 421 PLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGG 480
           PLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGG
Sbjct: 421 PLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGG 480

Query: 481 TPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQF 540
           TPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQF
Sbjct: 481 TPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQF 540

Query: 541 EDDDHGPPAPPNPFSHLTEGELEEYKRTIERKQQGLEENHELFSKSFISMEVPVMVVNGK 600
           EDDDHGPPAPPNPFSHLTEGELEEYKRTIERKQQGLEENHELFSKSFISMEVPVMVVNGK
Sbjct: 541 EDDDHGPPAPPNPFSHLTEGELEEYKRTIERKQQGLEENHELFSKSFISMEVPVMVVNGK 600

Query: 601 DDMHDVEDELAKRVSRLSTSTTIENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTP 660
           DDMHDVEDELAKRVSRLSTSTTIENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTP
Sbjct: 601 DDMHDVEDELAKRVSRLSTSTTIENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTP 660

Query: 661 SFLKKNKKKEKVEA 674
           SFLKKNKKKEKVEA
Sbjct: 661 SFLKKNKKKEKVEA 674


>gi|62912453 adducin 3 (gamma) isoform b [Homo sapiens]
          Length = 674

 Score = 1351 bits (3496), Expect = 0.0
 Identities = 674/674 (100%), Positives = 674/674 (100%)

Query: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60
           MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ
Sbjct: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60

Query: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPIN 120
           ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPIN
Sbjct: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPIN 120

Query: 121 DLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLS 180
           DLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLS
Sbjct: 121 DLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLS 180

Query: 181 FSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAV 240
           FSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAV
Sbjct: 181 FSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAV 240

Query: 241 SSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALG 300
           SSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALG
Sbjct: 241 SSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALG 300

Query: 301 ETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGS 360
           ETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGS
Sbjct: 301 ETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGS 360

Query: 361 HQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTV 420
           HQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTV
Sbjct: 361 HQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTV 420

Query: 421 PLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGG 480
           PLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGG
Sbjct: 421 PLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGG 480

Query: 481 TPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQF 540
           TPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQF
Sbjct: 481 TPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQF 540

Query: 541 EDDDHGPPAPPNPFSHLTEGELEEYKRTIERKQQGLEENHELFSKSFISMEVPVMVVNGK 600
           EDDDHGPPAPPNPFSHLTEGELEEYKRTIERKQQGLEENHELFSKSFISMEVPVMVVNGK
Sbjct: 541 EDDDHGPPAPPNPFSHLTEGELEEYKRTIERKQQGLEENHELFSKSFISMEVPVMVVNGK 600

Query: 601 DDMHDVEDELAKRVSRLSTSTTIENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTP 660
           DDMHDVEDELAKRVSRLSTSTTIENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTP
Sbjct: 601 DDMHDVEDELAKRVSRLSTSTTIENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTP 660

Query: 661 SFLKKNKKKEKVEA 674
           SFLKKNKKKEKVEA
Sbjct: 661 SFLKKNKKKEKVEA 674


>gi|9943848 adducin 3 (gamma) isoform a [Homo sapiens]
          Length = 706

 Score = 1334 bits (3453), Expect = 0.0
 Identities = 674/706 (95%), Positives = 674/706 (95%), Gaps = 32/706 (4%)

Query: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60
           MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ
Sbjct: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60

Query: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPIN 120
           ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPIN
Sbjct: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPIN 120

Query: 121 DLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLS 180
           DLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLS
Sbjct: 121 DLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLS 180

Query: 181 FSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAV 240
           FSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAV
Sbjct: 181 FSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAV 240

Query: 241 SSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALG 300
           SSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALG
Sbjct: 241 SSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALG 300

Query: 301 ETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGS 360
           ETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGS
Sbjct: 301 ETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGS 360

Query: 361 HQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTV 420
           HQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTV
Sbjct: 361 HQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTV 420

Query: 421 PLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGG 480
           PLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGG
Sbjct: 421 PLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGG 480

Query: 481 TPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQF 540
           TPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQF
Sbjct: 481 TPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQF 540

Query: 541 EDDDHGPPAPPNPFSHLTEGELEEYKRTIERKQQG------------------------- 575
           EDDDHGPPAPPNPFSHLTEGELEEYKRTIERKQQG                         
Sbjct: 541 EDDDHGPPAPPNPFSHLTEGELEEYKRTIERKQQGLEDAEQELLSDDASSVSQIQSQTQS 600

Query: 576 -------LEENHELFSKSFISMEVPVMVVNGKDDMHDVEDELAKRVSRLSTSTTIENIEI 628
                  LEENHELFSKSFISMEVPVMVVNGKDDMHDVEDELAKRVSRLSTSTTIENIEI
Sbjct: 601 PQNVPEKLEENHELFSKSFISMEVPVMVVNGKDDMHDVEDELAKRVSRLSTSTTIENIEI 660

Query: 629 TIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVEA 674
           TIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVEA
Sbjct: 661 TIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVEA 706


>gi|9257192 adducin 2 isoform a [Homo sapiens]
          Length = 726

 Score =  740 bits (1911), Expect = 0.0
 Identities = 386/732 (52%), Positives = 514/732 (70%), Gaps = 64/732 (8%)

Query: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60
           MS +      + PPP   P    YFDR +E+DPEY+R RN + DLRQDFN+MEQ+KRVT 
Sbjct: 1   MSEETVPEAASPPPPQGQP----YFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTM 56

Query: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPIN 120
           ILQSP+FRE+LE LIQEQMKKG+N + + AL+QIAD++ + S + F +  +++ M+TPIN
Sbjct: 57  ILQSPSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPIN 116

Query: 121 DLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLS 180
           DL  AD+ +  KGE+L RCK++S+YRL+DL+GWA L++TY+++R+SKEQDH +I P+G+S
Sbjct: 117 DLHTADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVS 176

Query: 181 FSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAV 240
            SE TAS+L+KVNI+GEVV++GS+   +D TGF  H+AIY+ RPDV+C+IH+HT ATAAV
Sbjct: 177 CSEVTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAV 236

Query: 241 SSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALG 300
           S+MK G+LP+S  +LL+GD+AYYD+ G +E++ +RI LQK LGP+CK+LVLRNHGVVALG
Sbjct: 237 SAMKWGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALG 296

Query: 301 ETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGS 360
           +T+EEAF+ IF++Q ACEIQV AL+ AGGV+NL +L+ +K++   + V +    G   G 
Sbjct: 297 DTVEEAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHR--PHEVGSVQWAGSTFGP 354

Query: 361 HQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTV 420
            QK ++GE EFE LMR LDNLGYRTGY YRHP ++EK +HKS+VEIPATVTAF FE+D  
Sbjct: 355 MQKSRLGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDGA 414

Query: 421 PLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGG 480
           P+  L+  AQ+QQ+EKTRWLN+PNTY++VNV +E +    SPR K TWMKA++  K S G
Sbjct: 415 PVPALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSG 474

Query: 481 TPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDK--PPST- 537
            PI+IE+PNQFVPL T+P EVLE RNKIREQNR D+K+AGPQSQLLA ++ +K   PST 
Sbjct: 475 MPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTE 534

Query: 538 ---MQFEDD---DHGPPAPPNPFSHLTEGELEEYKRTIERKQ------------------ 573
              M   D+   D      PNPFS LT+ ELEEYK+ +ERK+                  
Sbjct: 535 SQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPA 594

Query: 574 -------------------------QGLEENHELFSKSFISMEVPV------MVVNGKDD 602
                                    + LEE  +    S  +   P       +VVNG+++
Sbjct: 595 KSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREE 654

Query: 603 MHDVEDELAKRVSRLSTSTTIENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTPSF 662
               E+ L+K +S+++TS   +      K+       +SPEGSPSKSPSKKKKKFRTPSF
Sbjct: 655 EQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSF 714

Query: 663 LKKNKKKEKVEA 674
           LKK+KKKEKVE+
Sbjct: 715 LKKSKKKEKVES 726


>gi|9257190 adducin 2 isoform e [Homo sapiens]
          Length = 643

 Score =  687 bits (1772), Expect = 0.0
 Identities = 340/587 (57%), Positives = 451/587 (76%), Gaps = 15/587 (2%)

Query: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60
           MS +      + PPP   P    YFDR +E+DPEY+R RN + DLRQDFN+MEQ+KRVT 
Sbjct: 1   MSEETVPEAASPPPPQGQP----YFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTM 56

Query: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPIN 120
           ILQSP+FRE+LE LIQEQMKKG+N + + AL+QIAD++ + S + F +  +++ M+TPIN
Sbjct: 57  ILQSPSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPIN 116

Query: 121 DLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLS 180
           DL  AD+ +  KGE+L RCK++S+YRL+DL+GWA L++TY+++R+SKEQDH +I P+G+S
Sbjct: 117 DLHTADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVS 176

Query: 181 FSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAV 240
            SE TAS+L+KVNI+GEVV++GS+   +D TGF  H+AIY+ RPDV+C+IH+HT ATAAV
Sbjct: 177 CSEVTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAV 236

Query: 241 SSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALG 300
           S+MK G+LP+S  +LL+GD+AYYD+ G +E++ +RI LQK LGP+CK+LVLRNHGVVALG
Sbjct: 237 SAMKWGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALG 296

Query: 301 ETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGS 360
           +T+EEAF+ IF++Q ACEIQV AL+ AGGV+NL +L+ +K++   + V +    G   G 
Sbjct: 297 DTVEEAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHR--PHEVGSVQWAGSTFGP 354

Query: 361 HQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTV 420
            QK ++GE EFE LMR LDNLGYRTGY YRHP ++EK +HKS+VEIPATVTAF FE+D  
Sbjct: 355 MQKSRLGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDGA 414

Query: 421 PLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGG 480
           P+  L+  AQ+QQ+EKTRWLN+PNTY++VNV +E +    SPR K TWMKA++  K S G
Sbjct: 415 PVPALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSG 474

Query: 481 TPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDK--PPST- 537
            PI+IE+PNQFVPL T+P EVLE RNKIREQNR D+K+AGPQSQLLA ++ +K   PST 
Sbjct: 475 MPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTE 534

Query: 538 ---MQFEDD---DHGPPAPPNPFSHLTEGELEEYKRTIERKQQGLEE 578
              M   D+   D      PNPFS LT+ ELEEYK+ +ERK+  L+E
Sbjct: 535 SQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDE 581


>gi|29826319 adducin 1 (alpha) isoform a [Homo sapiens]
          Length = 737

 Score =  672 bits (1733), Expect = 0.0
 Identities = 377/748 (50%), Positives = 493/748 (65%), Gaps = 93/748 (12%)

Query: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60
           M+ D+   V+T+PPP + PHKERYFDR++EN+PEY+RERNM+PDLRQDFNMMEQ+KRV+ 
Sbjct: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60

Query: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPP--------LS 112
           ILQSPAF E+LE +IQEQ KKG NPTGLLALQQIAD++  N  + + + P        +S
Sbjct: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120

Query: 113 LGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHI 172
           LGMVTP+NDL G+D+ +Y KGEKL RCKLA+ YRL DLFGW+ L   +I+ R++ EQ+H 
Sbjct: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180

Query: 173 IIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHI 232
           +I+P GL +SE TAS+LVK+N+ G++VD+GSTNL ++  GF+ H+AIY+ RPDVKCV+HI
Sbjct: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240

Query: 233 HTLATAAVSSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLR 292
           HT A AAVS+MKCG+LPIS E+L LG+VAY+DY G L ++EE++ +QK LGP  KVL+LR
Sbjct: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300

Query: 293 NHGVVALGETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASG 352
           NHG+V++GE++EEAF+YI N+ +ACEIQV+ LA AGG DNL +L+ +KYKA + +  +  
Sbjct: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360

Query: 353 GGGVNMGSHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTA 412
           G G   GS  KW++GE EFE LMR LDNLGYRTGY YR+P +REK +  SDVE+PA+VT 
Sbjct: 361 GEGT--GSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTG 418

Query: 413 FSF--EDDTVPLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMK 470
           +SF  + D+   SPL++  Q+QQREKTRWLNS          EE +NG +SP++K  W K
Sbjct: 419 YSFASDGDSGTCSPLRHSFQKQQREKTRWLNSGR---GDEASEEGQNG-SSPKSKTKWTK 474

Query: 471 AEDSSKVSGGTPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIV 530
            ED  + S         PN FVPLNTNP EV E RNKIREQN  D+KTAGPQSQ+L G+V
Sbjct: 475 -EDGHRTSTSAV-----PNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVV 528

Query: 531 VDKPPSTMQFE---------DDDHGP-----PAPPNPFSHLTEGELEEYKRTIERKQQGL 576
           +D+  S +Q E         + ++ P        PNPF+ LT+ ELEEY+R +ERKQ+G 
Sbjct: 529 MDR--SLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGS 586

Query: 577 EEN----HELFSKS-----FISMEVPVMVVNGKDDM------HDVEDELAKRVSRLSTST 621
           EEN     E   KS      +    P   +  ++D+       D  D    + +    S 
Sbjct: 587 EENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDLVPEPTTGDDSDAATFKPTLPDLSP 646

Query: 622 TIENIEITIKSPEKIEEV------------LSPEGSPSKSP------------------- 650
              +  +     EK EE              SPE +P  +P                   
Sbjct: 647 DEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVAEEAAPSAVEEGAAADPG 706

Query: 651 ---------SKKKKKFRTPSFLKKNKKK 669
                    SKKKKKFRTPSFLKK+KKK
Sbjct: 707 SDGSPGKSPSKKKKKFRTPSFLKKSKKK 734


>gi|29826323 adducin 1 (alpha) isoform c [Homo sapiens]
          Length = 631

 Score =  660 bits (1703), Expect = 0.0
 Identities = 342/603 (56%), Positives = 446/603 (73%), Gaps = 38/603 (6%)

Query: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60
           M+ D+   V+T+PPP + PHKERYFDR++EN+PEY+RERNM+PDLRQDFNMMEQ+KRV+ 
Sbjct: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60

Query: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPP--------LS 112
           ILQSPAF E+LE +IQEQ KKG NPTGLLALQQIAD++  N  + + + P        +S
Sbjct: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120

Query: 113 LGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHI 172
           LGMVTP+NDL G+D+ +Y KGEKL RCKLA+ YRL DLFGW+ L   +I+ R++ EQ+H 
Sbjct: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180

Query: 173 IIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHI 232
           +I+P GL +SE TAS+LVK+N+ G++VD+GSTNL ++  GF+ H+AIY+ RPDVKCV+HI
Sbjct: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240

Query: 233 HTLATAAVSSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLR 292
           HT A AAVS+MKCG+LPIS E+L LG+VAY+DY G L ++EE++ +QK LGP  KVL+LR
Sbjct: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300

Query: 293 NHGVVALGETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASG 352
           NHG+V++GE++EEAF+YI N+ +ACEIQV+ LA AGG DNL +L+ +KYKA + +  +  
Sbjct: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360

Query: 353 GGGVNMGSHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTA 412
           G G   GS  KW++GE EFE LMR LDNLGYRTGY YR+P +REK +  SDVE+PA+VT 
Sbjct: 361 GEGT--GSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTG 418

Query: 413 FSF--EDDTVPLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMK 470
           +SF  + D+   SPL++  Q+QQREKTRWLNS          EE +NG +SP++K  W K
Sbjct: 419 YSFASDGDSGTCSPLRHSFQKQQREKTRWLNSGR---GDEASEEGQNG-SSPKSKTKWTK 474

Query: 471 AEDSSKVSGGTPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIV 530
            ED  + S         PN FVPLNTNP EV E RNKIREQN  D+KTAGPQSQ+L G+V
Sbjct: 475 -EDGHRTSTSAV-----PNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVV 528

Query: 531 VDKPPSTMQFE---------DDDHGP-----PAPPNPFSHLTEGELEEYKRTIERKQQGL 576
           +D+  S +Q E         + ++ P        PNPF+ LT+ ELEEY+R +ERKQ+G 
Sbjct: 529 MDR--SLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGS 586

Query: 577 EEN 579
           EEN
Sbjct: 587 EEN 589


>gi|89276787 adducin 2 isoform b [Homo sapiens]
          Length = 559

 Score =  657 bits (1696), Expect = 0.0
 Identities = 317/539 (58%), Positives = 424/539 (78%), Gaps = 6/539 (1%)

Query: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60
           MS +      + PPP   P    YFDR +E+DPEY+R RN + DLRQDFN+MEQ+KRVT 
Sbjct: 1   MSEETVPEAASPPPPQGQP----YFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTM 56

Query: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPIN 120
           ILQSP+FRE+LE LIQEQMKKG+N + + AL+QIAD++ + S + F +  +++ M+TPIN
Sbjct: 57  ILQSPSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPIN 116

Query: 121 DLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLS 180
           DL  AD+ +  KGE+L RCK++S+YRL+DL+GWA L++TY+++R+SKEQDH +I P+G+S
Sbjct: 117 DLHTADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVS 176

Query: 181 FSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHIHTLATAAV 240
            SE TAS+L+KVNI+GEVV++GS+   +D TGF  H+AIY+ RPDV+C+IH+HT ATAAV
Sbjct: 177 CSEVTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAV 236

Query: 241 SSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLRNHGVVALG 300
           S+MK G+LP+S  +LL+GD+AYYD+ G +E++ +RI LQK LGP+CK+LVLRNHGVVALG
Sbjct: 237 SAMKWGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALG 296

Query: 301 ETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASGGGGVNMGS 360
           +T+EEAF+ IF++Q ACEIQV AL+ AGGV+NL +L+ +K++   + V +    G   G 
Sbjct: 297 DTVEEAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHR--PHEVGSVQWAGSTFGP 354

Query: 361 HQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTV 420
            QK ++GE EFE LMR LDNLGYRTGY YRHP ++EK +HKS+VEIPATVTAF FE+D  
Sbjct: 355 MQKSRLGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDGA 414

Query: 421 PLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGG 480
           P+  L+  AQ+QQ+EKTRWLN+PNTY++VNV +E +    SPR K TWMKA++  K S G
Sbjct: 415 PVPALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSG 474

Query: 481 TPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQ 539
            PI+IE+PNQFVPL T+P EVLE RNKIREQNR D+K+AGPQSQLLA ++ +K  S ++
Sbjct: 475 MPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPVE 533


>gi|29826321 adducin 1 (alpha) isoform b [Homo sapiens]
          Length = 768

 Score =  656 bits (1693), Expect = 0.0
 Identities = 377/772 (48%), Positives = 494/772 (63%), Gaps = 110/772 (14%)

Query: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60
           M+ D+   V+T+PPP + PHKERYFDR++EN+PEY+RERNM+PDLRQDFNMMEQ+KRV+ 
Sbjct: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60

Query: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPP--------LS 112
           ILQSPAF E+LE +IQEQ KKG NPTGLLALQQIAD++  N  + + + P        +S
Sbjct: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120

Query: 113 LGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHI 172
           LGMVTP+NDL G+D+ +Y KGEKL RCKLA+ YRL DLFGW+ L   +I+ R++ EQ+H 
Sbjct: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180

Query: 173 IIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHI 232
           +I+P GL +SE TAS+LVK+N+ G++VD+GSTNL ++  GF+ H+AIY+ RPDVKCV+HI
Sbjct: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240

Query: 233 HTLATAAVSSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLR 292
           HT A AAVS+MKCG+LPIS E+L LG+VAY+DY G L ++EE++ +QK LGP  KVL+LR
Sbjct: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300

Query: 293 NHGVVALGETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASG 352
           NHG+V++GE++EEAF+YI N+ +ACEIQV+ LA AGG DNL +L+ +KYKA + +  +  
Sbjct: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360

Query: 353 GGGVNMGSHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTA 412
           G G   GS  KW++GE EFE LMR LDNLGYRTGY YR+P +REK +  SDVE+PA+VT 
Sbjct: 361 GEGT--GSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTG 418

Query: 413 FSF--EDDTVPLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGET-SPRTKITWM 469
           +SF  + D+   SPL++  Q+QQREKTRWLNS          EE +NG +   +TK+   
Sbjct: 419 YSFASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGD---EASEEGQNGSSPKSKTKVWTN 475

Query: 470 KAEDSSK-----VSGGTPIKI---------ED---------PNQFVPLNTNPNEVLEKRN 506
              D  K     +S G  +           ED         PN FVPLNTNP EV E RN
Sbjct: 476 ITHDHVKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRN 535

Query: 507 KIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQFE---------DDDHGP-----PAPPN 552
           KIREQN  D+KTAGPQSQ+L G+V+D+  S +Q E         + ++ P        PN
Sbjct: 536 KIREQNLQDIKTAGPQSQVLCGVVMDR--SLVQGELVTASKAIIEKEYQPHVIVSTTGPN 593

Query: 553 PFSHLTEGELEEYKRTIERKQQGLEEN----HELFSKS-----FISMEVPVMVVNGKDDM 603
           PF+ LT+ ELEEY+R +ERKQ+G EEN     E   KS      +    P   +  ++D+
Sbjct: 594 PFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPIKLEEDL 653

Query: 604 ------HDVEDELAKRVSRLSTSTTIENIEITIKSPEKIEEV------------LSPEGS 645
                  D  D    + +    S    +  +     EK EE              SPE +
Sbjct: 654 VPEPTTGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPA 713

Query: 646 PSKSP----------------------------SKKKKKFRTPSFLKKNKKK 669
           P  +P                            SKKKKKFRTPSFLKK+KKK
Sbjct: 714 PDPAPVAEEAAPSAVEEGAAADPGSDGSPGKSPSKKKKKFRTPSFLKKSKKK 765


>gi|29826325 adducin 1 (alpha) isoform d [Homo sapiens]
          Length = 662

 Score =  645 bits (1663), Expect = 0.0
 Identities = 342/627 (54%), Positives = 447/627 (71%), Gaps = 55/627 (8%)

Query: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60
           M+ D+   V+T+PPP + PHKERYFDR++EN+PEY+RERNM+PDLRQDFNMMEQ+KRV+ 
Sbjct: 1   MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM 60

Query: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPP--------LS 112
           ILQSPAF E+LE +IQEQ KKG NPTGLLALQQIAD++  N  + + + P        +S
Sbjct: 61  ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS 120

Query: 113 LGMVTPINDLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHI 172
           LGMVTP+NDL G+D+ +Y KGEKL RCKLA+ YRL DLFGW+ L   +I+ R++ EQ+H 
Sbjct: 121 LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHF 180

Query: 173 IIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHTGFSPHAAIYSTRPDVKCVIHI 232
           +I+P GL +SE TAS+LVK+N+ G++VD+GSTNL ++  GF+ H+AIY+ RPDVKCV+HI
Sbjct: 181 LIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHI 240

Query: 233 HTLATAAVSSMKCGILPISQESLLLGDVAYYDYQGSLEEQEERIQLQKVLGPSCKVLVLR 292
           HT A AAVS+MKCG+LPIS E+L LG+VAY+DY G L ++EE++ +QK LGP  KVL+LR
Sbjct: 241 HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR 300

Query: 293 NHGVVALGETLEEAFHYIFNVQLACEIQVQALAGAGGVDNLHVLDFQKYKAFTYTVAASG 352
           NHG+V++GE++EEAF+YI N+ +ACEIQV+ LA AGG DNL +L+ +KYKA + +  +  
Sbjct: 301 NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPV 360

Query: 353 GGGVNMGSHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTA 412
           G G   GS  KW++GE EFE LMR LDNLGYRTGY YR+P +REK +  SDVE+PA+VT 
Sbjct: 361 GEGT--GSPPKWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTG 418

Query: 413 FSF--EDDTVPLSPLKYMAQRQQREKTRWLNSPNTYMKVNVPEESRNGET-SPRTKITWM 469
           +SF  + D+   SPL++  Q+QQREKTRWLNS          EE +NG +   +TK+   
Sbjct: 419 YSFASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGD---EASEEGQNGSSPKSKTKVWTN 475

Query: 470 KAEDSSK-----VSGGTPIKI---------ED---------PNQFVPLNTNPNEVLEKRN 506
              D  K     +S G  +           ED         PN FVPLNTNP EV E RN
Sbjct: 476 ITHDHVKPLLQSLSSGVCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNTNPKEVQEMRN 535

Query: 507 KIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQFE---------DDDHGP-----PAPPN 552
           KIREQN  D+KTAGPQSQ+L G+V+D+  S +Q E         + ++ P        PN
Sbjct: 536 KIREQNLQDIKTAGPQSQVLCGVVMDR--SLVQGELVTASKAIIEKEYQPHVIVSTTGPN 593

Query: 553 PFSHLTEGELEEYKRTIERKQQGLEEN 579
           PF+ LT+ ELEEY+R +ERKQ+G EEN
Sbjct: 594 PFTTLTDRELEEYRREVERKQKGSEEN 620


>gi|89276790 adducin 2 isoform d [Homo sapiens]
          Length = 253

 Score =  222 bits (566), Expect = 8e-58
 Identities = 106/191 (55%), Positives = 148/191 (77%), Gaps = 4/191 (2%)

Query: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60
           MS +      + PPP   P    YFDR +E+DPEY+R RN + DLRQDFN+MEQ+KRVT 
Sbjct: 1   MSEETVPEAASPPPPQGQP----YFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTM 56

Query: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPIN 120
           ILQSP+FRE+LE LIQEQMKKG+N + + AL+QIAD++ + S + F +  +++ M+TPIN
Sbjct: 57  ILQSPSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPIN 116

Query: 121 DLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLS 180
           DL  AD+ +  KGE+L RCK++S+YRL+DL+GWA L++TY+++R+SKEQDH +I P+G+S
Sbjct: 117 DLHTADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVS 176

Query: 181 FSEATASNLVK 191
            SE TAS+L+K
Sbjct: 177 CSEVTASSLIK 187



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 38/101 (37%), Positives = 53/101 (52%), Gaps = 22/101 (21%)

Query: 439 WLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGGTPIKIEDPNQFVPLNTNP 498
           W    +TY+ + V +E  +   SP       K    S+V+  + IK              
Sbjct: 149 WAQLSDTYVTLRVSKEQDHFLISP-------KGVSCSEVTASSLIK-------------- 187

Query: 499 NEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQ 539
            EVLE RNKIREQNR D+K+AGPQSQLLA ++ +K  S ++
Sbjct: 188 -EVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPVE 227


>gi|9257180 adducin 2 isoform c [Homo sapiens]
          Length = 420

 Score =  222 bits (566), Expect = 8e-58
 Identities = 106/191 (55%), Positives = 148/191 (77%), Gaps = 4/191 (2%)

Query: 1   MSSDASQGVITTPPPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQRKRVTQ 60
           MS +      + PPP   P    YFDR +E+DPEY+R RN + DLRQDFN+MEQ+KRVT 
Sbjct: 1   MSEETVPEAASPPPPQGQP----YFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTM 56

Query: 61  ILQSPAFREDLECLIQEQMKKGHNPTGLLALQQIADYIMANSFSGFSSPPLSLGMVTPIN 120
           ILQSP+FRE+LE LIQEQMKKG+N + + AL+QIAD++ + S + F +  +++ M+TPIN
Sbjct: 57  ILQSPSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPIN 116

Query: 121 DLPGADTSSYVKGEKLTRCKLASLYRLVDLFGWAHLANTYISVRISKEQDHIIIIPRGLS 180
           DL  AD+ +  KGE+L RCK++S+YRL+DL+GWA L++TY+++R+SKEQDH +I P+G+S
Sbjct: 117 DLHTADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVS 176

Query: 181 FSEATASNLVK 191
            SE TAS+L+K
Sbjct: 177 CSEVTASSLIK 187



 Score =  142 bits (357), Expect = 1e-33
 Identities = 107/294 (36%), Positives = 143/294 (48%), Gaps = 80/294 (27%)

Query: 439 WLNSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGGTPIKIEDPNQFVPLNTNP 498
           W    +TY+ + V +E  +   SP       K    S+V+  + IK              
Sbjct: 149 WAQLSDTYVTLRVSKEQDHFLISP-------KGVSCSEVTASSLIK-------------- 187

Query: 499 NEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDK--PPST----MQFEDD---DHGPPA 549
            EVLE RNKIREQNR D+K+AGPQSQLLA ++ +K   PST    M   D+   D     
Sbjct: 188 -EVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEET 246

Query: 550 PPNPFSHLTEGELEEYKRTIERKQ------------------------------------ 573
            PNPFS LT+ ELEEYK+ +ERK+                                    
Sbjct: 247 VPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPASPVQSPAKEAETK 306

Query: 574 -------QGLEENHELFSKSFISMEVPV------MVVNGKDDMHDVEDELAKRVSRLSTS 620
                  + LEE  +    S  +   P       +VVNG+++    E+ L+K +S+++TS
Sbjct: 307 SPLVSPSKSLEEGTKKTETSKAATTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTS 366

Query: 621 TTIENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVEA 674
              +      K+       +SPEGSPSKSPSKKKKKFRTPSFLKK+KKKEKVE+
Sbjct: 367 ADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES 420


>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
          Length = 2663

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 59/241 (24%), Positives = 98/241 (40%), Gaps = 55/241 (22%)

Query: 450 NVPEESRNGETSPRT------------KITWMKAEDSSKVSGGTPIKIEDPNQFVPLNT- 496
           N  + +R GET  +             K T+  +E+SS  S     + ED   F P ++ 
Sbjct: 259 NPQQSNRKGETPLKVANSPTMVNLLLGKGTYTSSEESSTESS----EEEDAPSFAPSSSV 314

Query: 497 ---NPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQFEDDDHGPPAPPNP 553
              N +   EK  K + +N        P+ Q     V D+     +F++DD     PP  
Sbjct: 315 DGNNTDSEFEKGLKHKAKN--------PEPQKATAPVKDE----YEFDEDDEQDRVPPVD 362

Query: 554 FSHLTEGELEEYKRTIERKQQGLEENHELFSKSFISMEVPVMVVNGKDDMHDVEDELAKR 613
             HL +   ++Y++             E  S SFIS  +P M V      + +  + A  
Sbjct: 363 DKHLLK---KDYRK-------------ETKSNSFIS--IPKMEVKSYTKNNTIAPKKASH 404

Query: 614 VSRLSTSTTIENIEITIKSPEKIE---EVLSPEGSPSKSPSKKKKKFRTPSFLKKNKKKE 670
              LS ++  E+  +T+ + EK+      + P GS ++ PS  K++       KK KK+ 
Sbjct: 405 -RILSDTSDEEDASVTVGTGEKLRLSAHTILP-GSKTREPSNAKQQKEKNKVKKKRKKET 462

Query: 671 K 671
           K
Sbjct: 463 K 463



 Score = 37.0 bits (84), Expect = 0.059
 Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 10/94 (10%)

Query: 563  EEYKRTIERKQQGLEENHELFSKSFISMEVPVMVVNGKDDMHDVEDELAKRVSRLSTSTT 622
            E+YK    RK  G  E      K F+  +   +  N K D   +EDEL K +   ST   
Sbjct: 1378 EDYKEGGSRKDSGQYE------KDFLEADAYGVSYNMKAD---IEDELDKTIELFSTEKK 1428

Query: 623  IENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKK 656
             +N +   +  +KIE+ L P GS + +  K+KKK
Sbjct: 1429 DKN-DSEREPSKKIEKELKPYGSSAINILKEKKK 1461


>gi|206597543 hypothetical protein LOC118461 isoform 1 [Homo sapiens]
          Length = 1435

 Score = 37.0 bits (84), Expect = 0.059
 Identities = 50/199 (25%), Positives = 74/199 (37%), Gaps = 43/199 (21%)

Query: 416  EDDTVPLSPLKYMAQRQQREKTRWLNSPNT---------YMKVNVPEESRNGETS---PR 463
            ED   P  P     ++    K+ +L++P             + N P     GE+S   P 
Sbjct: 1012 EDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPA 1071

Query: 464  TKITWMKAEDSSKVSGGTPIKIEDPNQFVP-LNTNPNEVLEKR------------NKIRE 510
                W   E+SS+  GG  +  E+PNQ  P  +++P  V  +             + + E
Sbjct: 1072 ASNIW---EESSQAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLE 1128

Query: 511  QNRYDLKTAGPQSQLLAGIVVDKPPST-------MQFEDDDHGPPAPPNPFSHLTEGELE 563
             +  DL+T  P+  LL   V   P  T        Q E     PPA P      TE  L 
Sbjct: 1129 LSAEDLRTLSPRGSLLD--VATSPAGTSGRLELPAQLERTASKPPAVPPK----TEKALR 1182

Query: 564  EYKR--TIERKQQGLEENH 580
              K+  +  RK    +E H
Sbjct: 1183 RAKKLASKRRKTDQAQEKH 1201


>gi|166235186 APAF1 interacting protein [Homo sapiens]
          Length = 242

 Score = 36.2 bits (82), Expect = 0.10
 Identities = 45/189 (23%), Positives = 75/189 (39%), Gaps = 28/189 (14%)

Query: 152 GWAHLANTYISVRISKEQDHIIIIPRGLSFSEATASNLVKVNIIGEVVDQGSTNLKIDHT 211
           GW       IS+   K  D I I P G+        ++   +I  + +   S + K+  +
Sbjct: 39  GWVTGTGGGISL---KHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKS 95

Query: 212 GFSPHAAIYSTRPDVKCVIHIHTLATAAVSSMKCGI-LPISQESLLLG-----DVAYYDY 265
             +P      T      VIH H+ A    + +  G    I+ + ++ G        YY Y
Sbjct: 96  QCTPLFMNAYTMRGAGAVIHTHSKAAVMATLLFPGREFKITHQEMIKGIKKCTSGGYYRY 155

Query: 266 QGSL---------EEQEERIQLQKVLGP---SCKVLVLRNHGVVALGETLE------EAF 307
              L         EE++ + ++   +     SC VLV R HGV   GET E      E +
Sbjct: 156 DDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLV-RRHGVYVWGETWEKAKTMCECY 214

Query: 308 HYIFNVQLA 316
            Y+F++ ++
Sbjct: 215 DYLFDIAVS 223


>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
          Length = 1462

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 4/94 (4%)

Query: 550  PPNPFSHLTEGELEEYKRTIERKQQGLEENHELFSKSFISMEVPVMV-VNGKDDMHDVE- 607
            PP  F    E E+++ + T E K++ + EN+E    + +  E      ++GK D   V  
Sbjct: 1018 PPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSEEDLSGKHDTVTVSS 1077

Query: 608  --DELAKRVSRLSTSTTIENIEITIKSPEKIEEV 639
              D+  K  S+LS S T  N E  +   + I+ V
Sbjct: 1078 DLDQFTKDDSKLSISPTALNTEENVACLQNIQHV 1111


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 34.7 bits (78), Expect = 0.30
 Identities = 59/296 (19%), Positives = 110/296 (37%), Gaps = 21/296 (7%)

Query: 394 IREKPRHKSDVEIPATVTAFSFEDDTVP---LSPLKYMAQRQQREKTRWLNSPNTYMKVN 450
           ++E+ +  ++ + P    A S  +   P    SP K  A+  ++ K+       +  K  
Sbjct: 608 VKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAK 667

Query: 451 VPEESRNGETSPRTKITWMKAEDSSKVSGGTPIKIE--DPNQFV-PLNTNPNEVLEKRNK 507
            P ++     SP    + +KAE  S     +P+K E   P +   P+        + ++ 
Sbjct: 668 SPVKAE--AKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP 725

Query: 508 IREQNRYDLKTAGPQSQLLAGIVVDKPPS---TMQFEDDDHGPPA------PPNPFSHLT 558
           ++E+ +   K   P  +        K P    T+  +  +   PA      P + F    
Sbjct: 726 VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKA 785

Query: 559 EGELEEYKRTIERKQQGLEENHELFSKSFISMEVPVMVVNGKDDMHDVE-DELAKRVSRL 617
           +  ++E  ++ E+ +  L+E+ +   K     E     V  ++   +V+  E  K+    
Sbjct: 786 KSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845

Query: 618 STSTTIENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVE 673
               T +  E   K   K EE    E    K   KK+     P   K   KKE+ E
Sbjct: 846 KAPATPKTEE---KKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAE 898


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 33.9 bits (76), Expect = 0.50
 Identities = 29/117 (24%), Positives = 50/117 (42%), Gaps = 15/117 (12%)

Query: 557  LTEGELEEYKRTIERKQQGLEENHELFSKSFISMEVPVMVVNGKDDMHDVEDELAKRVSR 616
            ++E E E+  RT   K+  LEEN   + +      + V   +  ++  + E+E  ++   
Sbjct: 1355 VSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEK--- 1411

Query: 617  LSTSTTIENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVE 673
                      E   +  E+ EE    E   SKSP K +KK R    LK +K + + +
Sbjct: 1412 ----------EEEEEEEEEEEEEEEDENDDSKSPGKGRKKIR--KILKDDKLRTETQ 1456


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 33.9 bits (76), Expect = 0.50
 Identities = 29/117 (24%), Positives = 50/117 (42%), Gaps = 15/117 (12%)

Query: 557  LTEGELEEYKRTIERKQQGLEENHELFSKSFISMEVPVMVVNGKDDMHDVEDELAKRVSR 616
            ++E E E+  RT   K+  LEEN   + +      + V   +  ++  + E+E  ++   
Sbjct: 1393 VSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEK--- 1449

Query: 617  LSTSTTIENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVE 673
                      E   +  E+ EE    E   SKSP K +KK R    LK +K + + +
Sbjct: 1450 ----------EEEEEEEEEEEEEEEDENDDSKSPGKGRKKIR--KILKDDKLRTETQ 1494


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 33.5 bits (75), Expect = 0.66
 Identities = 33/119 (27%), Positives = 54/119 (45%), Gaps = 22/119 (18%)

Query: 561   ELEEYKRTIERKQQGLEENHELFSKSFISMEVPVMVVNGKDDMHDVEDE-LAKRVSRLST 619
             E EE+    E  ++G  E HE+  + FI +E            H VE+E   ++V R+  
Sbjct: 10379 EEEEFHEVEEYFEEG--EFHEV--EEFIKLE-----------QHRVEEEHRVEKVHRVIE 10423

Query: 620   STTIENIEI------TIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKV 672
                 E +E+        K PE  E+++ P+  P+K   +K+   + P   KK   +EKV
Sbjct: 10424 VFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKV 10482


>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
          Length = 1564

 Score = 33.1 bits (74), Expect = 0.86
 Identities = 36/122 (29%), Positives = 53/122 (43%), Gaps = 13/122 (10%)

Query: 561 ELEEYKRTIERKQQGLEENHELFSKSFISMEVPVMVVNGKDDMHDVEDELAKR-----VS 615
           E E+ K T ER  +  EEN E  +    S    +      D +H++  E+ ++     + 
Sbjct: 123 EKEDIKITKERTPESEEENVEWETNRDDSDNGDI----NYDYVHELSLEMKRQKIQRELM 178

Query: 616 RLSTSTTIENIEITIK---SPEKIEEVLSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKV 672
           +L      +  EI IK   SPE +   LSP  S  KS SK  K+  +P     +KK  K 
Sbjct: 179 KLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKS-SKSPKRKSSPKSSSASKKDRKT 237

Query: 673 EA 674
            A
Sbjct: 238 SA 239


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 32.0 bits (71), Expect = 1.9
 Identities = 44/221 (19%), Positives = 87/221 (39%), Gaps = 22/221 (9%)

Query: 465 KITWMKAEDSSKVSGGTPIKIEDPNQFVPLNTNPNE---VLEKRNKIREQNRYDLKTA-- 519
           K  + K++D     GGTP+K +   +     TNP     V EK  +  E ++  LK++  
Sbjct: 112 KAEYKKSKDEK---GGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHE 168

Query: 520 GPQSQLLAGIVVDKPPS----------TMQFEDDDHGPPAPPNPFSHLTEGELEEYKRTI 569
             QS+         P S          + + + D          F H         K+ +
Sbjct: 169 NEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNP----KKDL 224

Query: 570 ERKQQGLEENHELFSKSFISMEVPVMVVNGKDDMHDVEDELAKRVSRLSTSTTIENIEIT 629
           +R +   +   E+ S++ ++++  ++V    D+  + +  L       S + +++  + T
Sbjct: 225 KRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYT 284

Query: 630 IKSPEKIEEVLSPEGSPSKSPSKKKKKFRTPSFLKKNKKKE 670
            K  +K  +  S   S     +KK  K    +  K +KKK+
Sbjct: 285 KKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKD 325


>gi|40255052 IQ motif containing with AAA domain 1 [Homo sapiens]
          Length = 822

 Score = 32.0 bits (71), Expect = 1.9
 Identities = 28/135 (20%), Positives = 62/135 (45%), Gaps = 15/135 (11%)

Query: 550 PPNPFSHLTEGELEEYKRTIERKQQGLEENHEL-FSKSFISMEVPVMVVNGKDDMHDVED 608
           PP  F+ ++   ++  K  ++R +  ++  HE  + ++ ++++  + ++ G D   +++D
Sbjct: 242 PPPLFNEVSATVIQAEK--VDRLRNEVQIKHEEDYREALVTIKNDLKLIEGVDIKENLQD 299

Query: 609 ELAKRVSRLSTST-------TIENIEITIKSPEK-----IEEVLSPEGSPSKSPSKKKKK 656
           ++          T        +E     I   +K     IE++++ +    K+  KKKKK
Sbjct: 300 QIRHWFIECRNLTGTFPDYPDVEEGGSAIIFSDKTIQQVIEDIIANQEEEEKNKKKKKKK 359

Query: 657 FRTPSFLKKNKKKEK 671
            + P   KK KK  K
Sbjct: 360 EKQPKKAKKQKKGTK 374


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 39/170 (22%), Positives = 69/170 (40%), Gaps = 19/170 (11%)

Query: 506  NKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQFEDDDHGPPAPPN--PFSHLTEGELE 563
            NK+R     + K    +S+L       +  S +  +D++ G        PF      + +
Sbjct: 2148 NKMRRMINKEEKMTEEESKLA------RKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRK 2201

Query: 564  EYKRTIERKQQGLEENHELFSKSFISMEVPVMVVNGKDDMHDVEDELAKRVSRLSTSTTI 623
            E KR  + K++   +  E+ S+   S E+  ++    D++   E   ++           
Sbjct: 2202 EAKRGDKPKEKFSSQVDEVESEEHFSEEMESLL----DELEKQESLSSEEEEEREEEEER 2257

Query: 624  ENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVE 673
            E  E+  +  E+ EE    E    K   +KKKK       KK KKKE+V+
Sbjct: 2258 EEEEVREEEEERKEEEEGEEKQVEKEEEEKKKK-------KKEKKKEEVQ 2300


>gi|117190342 PHD finger protein 2 [Homo sapiens]
          Length = 1096

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 63/306 (20%), Positives = 118/306 (38%), Gaps = 45/306 (14%)

Query: 373 GLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEIPATVTAFSFEDDTVPLSPLKYMAQRQ 432
           G +    N      Y  +H L   K  HKS  ++P  +   +   +    S  K  A  +
Sbjct: 358 GSLTQFPNFETACWYMGKHLLEAFKGSHKSGKQLPPHLVQGAKILNGAFRSWTKKQALAE 417

Query: 433 QREKTRWLNSPNTYMKVNVPEE--SRNGETSPRTKITWMKAEDSSKVSGGTPIKIEDPNQ 490
             ++      P+  +K    E   S N   + R ++  + + D  +V  G   K E P+ 
Sbjct: 418 HEDELPEHFKPSQLIKDLAKEIRLSENASKAVRPEVNTVASSD--EVCDGDREKEEPPSP 475

Query: 491 FVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQFEDDDHGPPAP 550
                T P  +LEK +K  ++    +K   P         + KPP           PP P
Sbjct: 476 IEA--TPPQSLLEKVSK--KKTPKTVKMPKPSK-------IPKPPK----------PPKP 514

Query: 551 PNPFSHLTEGELEEYKRTIERKQQGLEENHELFSKSFISMEVP---VMVVNGKDDMHDVE 607
           P P             +T++ K  G ++  +  S+   S  +P   ++  + K+ +  +E
Sbjct: 515 PRP------------PKTLKLKDGGKKKGKK--SRESASPTIPNLDLLEAHTKEALTKME 560

Query: 608 DELAKRVSRLSTSTTIENIEITIKSPEKIEEVLSPEGSPSKSPSKKKKKFRTPSFLKKNK 667
                + ++   S   +++   +     +E +   E + SKS +K K K   P  L K +
Sbjct: 561 PPKKGKATKSVLSVPNKDV---VHMQNDVERLEIREQTKSKSEAKWKYKNSKPDSLLKME 617

Query: 668 KKEKVE 673
           +++K+E
Sbjct: 618 EEQKLE 623


>gi|19923599 calmin [Homo sapiens]
          Length = 1002

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 18/50 (36%), Positives = 24/50 (48%), Gaps = 3/50 (6%)

Query: 8   GVITTP---PPPSMPHKERYFDRINENDPEYIRERNMSPDLRQDFNMMEQ 54
           GV TTP   P P  PH++       ENDP    +   SP+L    N +E+
Sbjct: 804 GVGTTPASEPAPLAPHEDHQQRETKENDPMDSHQSQESPNLENIANPLEE 853


>gi|150418007 RAN binding protein 2 [Homo sapiens]
          Length = 3224

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 2/45 (4%)

Query: 605  DVEDELAKRVSRLSTSTTIE--NIEITIKSPEKIEEVLSPEGSPS 647
            D+E     +V  L  S   E  +I  T K+PEK +E   PE SPS
Sbjct: 2584 DIEQSSDSKVKNLFASFPTEESSINYTFKTPEKAKEKKKPEDSPS 2628


>gi|27894339 keratin 23 [Homo sapiens]
          Length = 422

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 55/265 (20%), Positives = 100/265 (37%), Gaps = 59/265 (22%)

Query: 368 EIEFEGLMRTLDNLGYRTG------YAYRHPLIREKPRHKSDVE---IPATVTAFSFEDD 418
           EIE EGL RTLDNL   T          R  LI  K  H+ ++E   +P+     + + D
Sbjct: 172 EIEVEGLRRTLDNLTIVTTDLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNV-NVKVD 230

Query: 419 TVPLSPL-----------KYMAQRQQREKTRWLNSPNTYMKVNVPE----ESRNGETSPR 463
           T P   L           + + +++ R+   W    +  M          +SR G+    
Sbjct: 231 TGPREDLIKVLEDMRQEYELIIKKKHRDLDTWYKEQSAAMSQEAASPATVQSRQGDIH-E 289

Query: 464 TKITWMKAEDSSKVSGGTPIKIED-----PNQFVPLNTNPNEVLEKRNKIREQNRYDLKT 518
            K T+   E   +    T   +E+      +++     +  E++    +   Q R++L+ 
Sbjct: 290 LKRTFQALEIDLQTQYSTKSALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRHELER 349

Query: 519 AGPQSQLLAGIVVDKPPSTMQFEDDDHGPPAPPNPFSHLTEGELEEYKRTIERKQQGLEE 578
              + Q+L GI                         +HL E E+  Y+R +E + +G  E
Sbjct: 350 QNNEYQVLLGIK------------------------THL-EKEITTYRRLLEGESEGTRE 384

Query: 579 NHELFSKSFISMEVPVM---VVNGK 600
             +   K   + ++  +    +NG+
Sbjct: 385 ESKSSMKVSATPKIKAITQETINGR 409


>gi|5031873 lectin, mannose-binding, 1 precursor [Homo sapiens]
          Length = 510

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 14/36 (38%), Positives = 20/36 (55%)

Query: 550 PPNPFSHLTEGELEEYKRTIERKQQGLEENHELFSK 585
           PP P   ++E E E+Y+   E  QQ L++  E F K
Sbjct: 274 PPTPDKEISEKEKEKYQEEFEHFQQELDKKKEEFQK 309


>gi|117968420 NUF2, NDC80 kinetochore complex component [Homo
           sapiens]
          Length = 464

 Score = 31.2 bits (69), Expect = 3.3
 Identities = 34/118 (28%), Positives = 59/118 (50%), Gaps = 13/118 (11%)

Query: 563 EEYKRTIER---KQQGLEENHELFSKS---FISMEVPVMVVNGKDDMHDVEDELAKRVSR 616
           E+ K T+++    +Q + E +E++  S     S ++ V +   K  + D+ D   K  S 
Sbjct: 256 EKMKDTVQKLKNARQEVVEKYEIYGDSVDCLPSCQLEVQLYQKK--IQDLSDNREKLASI 313

Query: 617 LSTSTTIENIEITIKSPE-KIEEVLSPEGSPSKSPSKKKKKFRTPSFLKKNKKKEKVE 673
           L  S    N+E  I+S E +++++ + E S  +    KK+K  T  F K NKK E V+
Sbjct: 314 LKESL---NLEDQIESDESELKKLKTEENSFKRLMIVKKEKLATAQF-KINKKHEDVK 367


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,815,199
Number of Sequences: 37866
Number of extensions: 1329032
Number of successful extensions: 4399
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 4289
Number of HSP's gapped (non-prelim): 108
length of query: 674
length of database: 18,247,518
effective HSP length: 109
effective length of query: 565
effective length of database: 14,120,124
effective search space: 7977870060
effective search space used: 7977870060
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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