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Search of human proteins with 98986453
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic
[Homo sapiens]
(1940 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 3754 0.0
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 3241 0.0
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 3231 0.0
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 3231 0.0
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 3220 0.0
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 3196 0.0
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 3070 0.0
gi|156104908 myosin heavy chain 6 [Homo sapiens] 3054 0.0
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 3040 0.0
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 2586 0.0
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 2300 0.0
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 1424 0.0
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 1424 0.0
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 1417 0.0
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 1417 0.0
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 1405 0.0
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 1397 0.0
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 1303 0.0
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 1298 0.0
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 1288 0.0
gi|153945715 myosin VC [Homo sapiens] 606 e-173
gi|215982791 myosin VA isoform 1 [Homo sapiens] 603 e-172
gi|215982794 myosin VA isoform 2 [Homo sapiens] 599 e-171
gi|122937345 myosin VB [Homo sapiens] 583 e-166
gi|28416946 myosin 18A isoform a [Homo sapiens] 504 e-142
gi|42794779 myosin 18A isoform b [Homo sapiens] 502 e-141
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 490 e-138
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 490 e-138
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 490 e-138
gi|154354979 myosin X [Homo sapiens] 478 e-134
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 3754 bits (9735), Expect = 0.0
Identities = 1940/1940 (100%), Positives = 1940/1940 (100%)
Query: 1 MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKV 60
MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKV
Sbjct: 1 MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKV 60
Query: 61 TVETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSG 120
TVETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSG
Sbjct: 61 TVETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSG 120
Query: 121 LFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
LFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
Sbjct: 121 LFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
Query: 181 SGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRND 240
SGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRND
Sbjct: 181 SGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRND 240
Query: 241 NSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIE 300
NSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIE
Sbjct: 241 NSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIE 300
Query: 301 LLLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHY 360
LLLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHY
Sbjct: 301 LLLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHY 360
Query: 361 GNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQ 420
GNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQ
Sbjct: 361 GNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQ 420
Query: 421 VHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCIN 480
VHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCIN
Sbjct: 421 VHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCIN 480
Query: 481 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECM 540
FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECM
Sbjct: 481 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECM 540
Query: 541 FPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKD 600
FPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKD
Sbjct: 541 FPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKD 600
Query: 601 PLNETVVGLYQKSSNRLLAHLYATFATADADSGKKKVAKKKGSSFQTVSALFRENLNKLM 660
PLNETVVGLYQKSSNRLLAHLYATFATADADSGKKKVAKKKGSSFQTVSALFRENLNKLM
Sbjct: 601 PLNETVVGLYQKSSNRLLAHLYATFATADADSGKKKVAKKKGSSFQTVSALFRENLNKLM 660
Query: 661 SNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFK 720
SNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFK
Sbjct: 661 SNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFK 720
Query: 721 QRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDD 780
QRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDD
Sbjct: 721 QRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDD 780
Query: 781 RLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPL 840
RLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPL
Sbjct: 781 RLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPL 840
Query: 841 LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLL 900
LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLL
Sbjct: 841 LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLL 900
Query: 901 DAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL 960
DAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL
Sbjct: 901 DAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL 960
Query: 961 TLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNS 1020
TLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNS
Sbjct: 961 TLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNS 1020
Query: 1021 LNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDER 1080
LNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDER
Sbjct: 1021 LNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDER 1080
Query: 1081 LKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY 1140
LKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY
Sbjct: 1081 LKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY 1140
Query: 1141 ARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADS 1200
ARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADS
Sbjct: 1141 ARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADS 1200
Query: 1201 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 1260
VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA
Sbjct: 1201 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 1260
Query: 1261 RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQL 1320
RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQL
Sbjct: 1261 RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQL 1320
Query: 1321 EEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 1380
EEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA
Sbjct: 1321 EEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 1380
Query: 1381 IQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLA 1440
IQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLA
Sbjct: 1381 IQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLA 1440
Query: 1441 AALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVK 1500
AALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVK
Sbjct: 1441 AALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVK 1500
Query: 1501 RENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKIL 1560
RENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKIL
Sbjct: 1501 RENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKIL 1560
Query: 1561 RIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKME 1620
RIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKME
Sbjct: 1561 RIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKME 1620
Query: 1621 GDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRAN 1680
GDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRAN
Sbjct: 1621 GDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRAN 1680
Query: 1681 LLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQS 1740
LLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQS
Sbjct: 1681 LLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQS 1740
Query: 1741 EVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE 1800
EVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE
Sbjct: 1741 EVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE 1800
Query: 1801 AEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRK 1860
AEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRK
Sbjct: 1801 AEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRK 1860
Query: 1861 NVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNK 1920
NVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNK
Sbjct: 1861 NVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNK 1920
Query: 1921 LRAKTRDFTSSRMVVHESEE 1940
LRAKTRDFTSSRMVVHESEE
Sbjct: 1921 LRAKTRDFTSSRMVVHESEE 1940
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 3241 bits (8403), Expect = 0.0
Identities = 1636/1926 (84%), Positives = 1798/1926 (93%)
Query: 2 SSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKVT 61
SSD EM VFG AAP+LRKSEKERIEAQN+PFDAKT FV + KE Y K I+S + GKVT
Sbjct: 4 SSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVT 63
Query: 62 VETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGL 121
V+TE TL V+ + V+ MNPPK+D+IEDMAM+THL+EP VLYNLK+RY +WMIYTYSGL
Sbjct: 64 VKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGL 123
Query: 122 FCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 181
FCVTVNPYKWLPVY PEVV YRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES
Sbjct: 124 FCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGES 183
Query: 182 GAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDN 241
GAGKTVNTKRVIQYFATIA TG+ K + KM+GTLEDQIISANPLLEAFGNAKTVRNDN
Sbjct: 184 GAGKTVNTKRVIQYFATIAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDN 243
Query: 242 SSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIEL 301
SSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQI SNKKP+LIE+
Sbjct: 244 SSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEM 303
Query: 302 LLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYG 361
LLITTNPYDY F+SQGEI V SIDD EEL+ATDSAIDILGFTPEEK +YKLTGAVMHYG
Sbjct: 304 LLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYG 363
Query: 362 NMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQV 421
NMKFKQKQREEQAEPDGTEVADK AYL LNS+DLLKALC+PRVKVGNEYVTKGQTV QV
Sbjct: 364 NMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQV 423
Query: 422 HHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINF 481
++AV AL+K+VYEK+FLWMVTRINQQLDTK PRQ+FIGVLDIAGFEIF++NSLEQLCINF
Sbjct: 424 YNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINF 483
Query: 482 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMF 541
TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKP+GIFSILEEECMF
Sbjct: 484 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMF 543
Query: 542 PKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDP 601
PKATDTSFKNKLYDQHLGKS NFQKPKVVKG+AEAHFSLIHYAGTVDY+++GWL+KNKDP
Sbjct: 544 PKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDP 603
Query: 602 LNETVVGLYQKSSNRLLAHLYATFATADADSGKKKVAKKKGSSFQTVSALFRENLNKLMS 661
LN+TVVGLYQKS+ + LA L++T+A+A+ADS KK AKKKGSSFQTVSALFRENLNKLM+
Sbjct: 604 LNDTVVGLYQKSAMKTLASLFSTYASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMT 663
Query: 662 NLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQ 721
NLR+THPHFVRCIIPNETKTPGAMEH LVLHQLRCNGVLEGIRICRKGFP+RILYGDFKQ
Sbjct: 664 NLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQ 723
Query: 722 RYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDR 781
RY+VLNASAIPEGQFIDSKKA EKLLASIDIDHTQYKFGHTKVFFKAGLLG LEEMRD++
Sbjct: 724 RYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEK 783
Query: 782 LAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLL 841
LA++ITRTQAVCRGFLMRVE+QKM+QRRE++FCIQYN+R+FMNVKHWPWMKLFFKIKPLL
Sbjct: 784 LAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLL 843
Query: 842 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLD 901
KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEK+VTL++EKNDLQLQVQ+E+++L D
Sbjct: 844 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 903
Query: 902 AEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 961
AEERC+QLIK K QLEAKIKEVTERAE+EEEINAELTAKKRKLEDECSELKKDIDDLELT
Sbjct: 904 AEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELT 963
Query: 962 LAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSL 1021
LAKVEKEKHATENKVKNLTEE++GLDETIAKL++EKKALQE HQQ LDDLQAEEDKVN L
Sbjct: 964 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNIL 1023
Query: 1022 NKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERL 1081
K K+KLEQQV+DLE SLEQEKKLR+DLER KRKLEGDLKLAQES +D+ENDKQQLDE+L
Sbjct: 1024 TKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKL 1083
Query: 1082 KKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYA 1141
+KK+FE L SK+EDEQ + +Q QKKIKELQARIEEL EEIEAERA+RAK EKQRSD +
Sbjct: 1084 EKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLS 1143
Query: 1142 RELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSV 1201
RELEE+SERLEEAGG TS Q+ELNKKREAEF KLRRDLEEATLQHEAMVAALRKKHADS+
Sbjct: 1144 RELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSM 1203
Query: 1202 AELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEAR 1261
AELGEQIDNLQRVKQKLEKEKSE K+E DDLSS+ E++SK+K NLEK+CR+LEDQ+SE +
Sbjct: 1204 AELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELK 1263
Query: 1262 GKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLE 1321
K EE QR +++LT Q++RLQTEAGE SRQL+EK+++VSQLSRSKQA TQQ EELK QLE
Sbjct: 1264 TKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLE 1323
Query: 1322 EENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAI 1381
EE KAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAI
Sbjct: 1324 EETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAI 1383
Query: 1382 QRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAA 1441
QRTEELEEAKKKLAQRLQ++EE VEAVNAKCASLEKTKQRLQ EVEDLM+DVER+N+ A
Sbjct: 1384 QRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACA 1443
Query: 1442 ALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKR 1501
ALDKKQRNFDKVL+EWK K EE+QAELEAS KESRSLSTELFK+KN YEE+LDQLET++R
Sbjct: 1444 ALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRR 1503
Query: 1502 ENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILR 1561
ENKNL+QEI+DLTEQIAE GK IHELEK +KQ+E EK +IQ ALEEAEA+LEHEE KILR
Sbjct: 1504 ENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILR 1563
Query: 1562 IQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEG 1621
IQLEL QVKSE+DRKIAEKDEEI+QLKRN+ R VETMQS LDAE+RSRN+A+R+KKKMEG
Sbjct: 1564 IQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEG 1623
Query: 1622 DLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANL 1681
DLNE+EIQL+HANR AAE+L++ R+ QG LK+TQLHLDDALRGQEDLKEQLAIVERRANL
Sbjct: 1624 DLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANL 1683
Query: 1682 LQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSE 1741
LQAE+EEL ATLEQTER+RK+AEQELLD++ERVQLLHTQNTSLI+TKKKLE D+ QLQSE
Sbjct: 1684 LQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSE 1743
Query: 1742 VEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEA 1801
VE+ +++RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEA
Sbjct: 1744 VEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEA 1803
Query: 1802 EQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKN 1861
EQLALKGGKKQIQKLE R+RELE E+E EQK+N E+VKGLRK+ERRVKELTYQ+EEDRKN
Sbjct: 1804 EQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKN 1863
Query: 1862 VLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKL 1921
VLRLQDLVDKLQ KVKSYKRQAEEA+EQ+NA+L+KFRK QHELEEAEERADIAESQVNKL
Sbjct: 1864 VLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKL 1923
Query: 1922 RAKTRD 1927
R K+R+
Sbjct: 1924 RVKSRE 1929
Score = 228 bits (581), Expect = 4e-59
Identities = 228/973 (23%), Positives = 428/973 (43%), Gaps = 112/973 (11%)
Query: 844 AETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAES------- 896
A+ KE ++E Q+T D+L E K L + L Q+ +DL+ ++ E
Sbjct: 993 AKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLE 1052
Query: 897 --------------ENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKR 942
E+ +D E QL + + E +I + + EDE+ + +L K +
Sbjct: 1053 RAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIK 1112
Query: 943 KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELS---GLDETIAKLTREKKA 999
+L+ EL ++I+ + AK EK++ +++ ++E L G +L ++++A
Sbjct: 1113 ELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREA 1172
Query: 1000 ----------------------LQEAHQQALDDLQAEEDKVN----SLNKTKSKLEQQVE 1033
L++ H ++ +L + D + L K KS+L+ + +
Sbjct: 1173 EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETD 1232
Query: 1034 DLESSLEQEKKLRVDLERNKRKLE---GDLKLAQESILDLENDKQQLDERLKKKDFEYC- 1089
DL S+ E K + +LE+ R LE +LK +E L ND RL+ + EY
Sbjct: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292
Query: 1090 QLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSE 1149
QL K L Q ++++ +LEEE +A+ A + R D E+ E
Sbjct: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352
Query: 1150 RLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQID 1209
E G Q L+K +E + R E +Q + +KK A + E E ++
Sbjct: 1353 EQE---GKAELQRALSKAN-SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVE 1408
Query: 1210 NLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQR 1269
+ LEK K + E++DL +E + + A L+K R + LSE + K EE Q
Sbjct: 1409 AVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQA 1468
Query: 1270 SLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNA 1329
L + L TE ++ EE + L R + Q+ +L Q+ E K
Sbjct: 1469 ELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGK---- 1524
Query: 1330 LAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS--------------EVAQWRTK 1375
H+ + +++Q E+E K E+Q AL +A + E+ Q +++
Sbjct: 1525 -------QIHELEKIKKQVEQE---KCEIQAALEEAEASLEHEEGKILRIQLELNQVKSE 1574
Query: 1376 YETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVER 1435
+ ++ EE+++ K+ + ++ + ++A + K++++G++ ++ + +
Sbjct: 1575 VDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNH 1634
Query: 1436 ANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNA-YEEALD 1494
AN LAA + RN +L E + +++ E LKE ++ L A EE
Sbjct: 1635 ANRLAAESLRNYRNTQGILKETQLHLDDALRGQE-DLKEQLAIVERRANLLQAEIEELWA 1693
Query: 1495 QLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEH 1554
LE +R K EQE+ D +E++ L ++K++E + + +Q +EE +
Sbjct: 1694 TLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRN 1753
Query: 1555 EEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALD-AEVRSRNEAI 1613
E K + + + E+ +K + +E++K+N ++TV+ +Q LD AE +
Sbjct: 1754 AEEKAKKAITDAAMMAEEL-KKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1812
Query: 1614 RLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLA 1673
+ +K+E + E+E ++ + ++ AE +K LR + ++K+ + +ED K L
Sbjct: 1813 KQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKEL------TYQTEEDRKNVLR 1866
Query: 1674 IVERRANLLQAEVEELRATLEQTE--------RARKLAEQELLDSNERVQLLHTQNTSL- 1724
+ + + LQA+V+ + E+ E + RKL + EL ++ ER + +Q L
Sbjct: 1867 L-QDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKL-QHELEEAEERADIAESQVNKLR 1924
Query: 1725 -----IHTKKKLE 1732
+HTK E
Sbjct: 1925 VKSREVHTKISAE 1937
Score = 84.3 bits (207), Expect = 1e-15
Identities = 86/346 (24%), Positives = 152/346 (43%), Gaps = 48/346 (13%)
Query: 1636 QAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVE-ELRATLE 1694
++AET K + +++ + + T+ L + +++L+E++ + + N LQ +V+ E + +
Sbjct: 844 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 903
Query: 1695 QTERARKLA------EQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRD 1748
ER +L E ++ + ER + N L K+KLE + +L+ +++D
Sbjct: 904 AEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELT 963
Query: 1749 ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE----QTVKDLQHRLDEAEQL 1804
E++ + EE+ +T A L + KK L+ QT+ DLQ D+ L
Sbjct: 964 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNIL 1023
Query: 1805 ALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVK---ELTYQSEEDR-- 1859
K KLE ++ +LE LE E+K + + RK E +K E T E D+
Sbjct: 1024 T-----KAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQ 1078
Query: 1860 ------KNVLRLQDLVDK----------LQVKVKSYKRQAEEADEQANAHLTKFRKAQ-- 1901
K + +L+ K LQ K+K + + EE E+ A KA+
Sbjct: 1079 LDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQ 1138
Query: 1902 -----HELEEAEERADIA----ESQVNKLRAKTRDFTSSRMVVHES 1938
ELEE ER + A +QV + + +F R + E+
Sbjct: 1139 RSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEA 1184
Score = 52.0 bits (123), Expect = 6e-06
Identities = 53/218 (24%), Positives = 92/218 (42%), Gaps = 37/218 (16%)
Query: 842 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLD 901
K+ + + A M EE +K +D A E +K LE+ + DLQ ++ + L
Sbjct: 1757 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTV-------KDLQHRLDEAEQLALK 1809
Query: 902 AEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 961
++ Q +LEA+++E+ E+E++ NAE RK E EL
Sbjct: 1810 GGKKQIQ------KLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKEL---------- 1853
Query: 962 LAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSL 1021
+ TE KN+ +D+ AK+ K+ +EA +Q+ +L +
Sbjct: 1854 -------TYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANL-------SKF 1899
Query: 1022 NKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGD 1059
K + +LE+ E + + Q KLRV K+ +
Sbjct: 1900 RKLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE 1937
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 3231 bits (8378), Expect = 0.0
Identities = 1639/1932 (84%), Positives = 1788/1932 (92%), Gaps = 5/1932 (0%)
Query: 1 MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKV 60
MSSD+E+ VFG AAPFLRKSE+ERIEAQN+PFDAKT FV + KE + KG I+S + GKV
Sbjct: 1 MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60
Query: 61 TVETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSG 120
TV+TE TL VK + V+ MNPPK+D+IEDMAM+THL+EPAVLYNLK+RY +WMIYTYSG
Sbjct: 61 TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
Query: 121 LFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
LFCVTVNPYKWLPVY PEVV YRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
Sbjct: 121 LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
Query: 181 SGAGKTVNTKRVIQYFATIAATGDLAKKK--DSKMKGTLEDQIISANPLLEAFGNAKTVR 238
SGAGKTVNTKRVIQYFATIA TG+ K++ K++GTLEDQIISANPLLEAFGNAKTVR
Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240
Query: 239 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL 298
NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRV FQLKAERSYHIFYQI SNKKPEL
Sbjct: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300
Query: 299 IELLLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVM 358
IE+LLITTNPYDYPF+SQGEI VASIDD EEL+ATDSAIDILGFT EEK +YKLTGAVM
Sbjct: 301 IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360
Query: 359 HYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTV 418
HYGN+KFKQKQREEQAEPDGTEVADK AYL LNS+DLLKALC+PRVKVGNEYVTKGQTV
Sbjct: 361 HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420
Query: 419 DQVHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLC 478
+QV +AV AL+K+VYEK+FLWMV RINQQLDTK PRQ+FIGVLDIAGFEIF++NSLEQLC
Sbjct: 421 EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
Query: 479 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 538
INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
Query: 539 CMFPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKN 598
CMFPKATDTSFKNKLYDQHLGKS NFQKPKVVKG+AEAHF+LIHYAG VDY+++GWLEKN
Sbjct: 541 CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600
Query: 599 KDPLNETVVGLYQKSSNRLLAHLYATFATAD---ADSGKKKVAKKKGSSFQTVSALFREN 655
KDPLNETVVGLYQKS+ + LA L++ TA+ A G KK KKKGSSFQTVSALFREN
Sbjct: 601 KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660
Query: 656 LNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRIL 715
LNKLM+NLR+THPHFVRCIIPNETKTPGAMEH LVLHQLRCNGVLEGIRICRKGFP+RIL
Sbjct: 661 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720
Query: 716 YGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLE 775
Y DFKQRY+VLNASAIPEGQFIDSKKA EKLLASIDIDHTQYKFGHTKVFFKAGLLG LE
Sbjct: 721 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780
Query: 776 EMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFF 835
EMRDD+LA+LITRTQA CRGFL RVE+Q+MV+RRE+IFCIQYNIRSFMNVKHWPWMKLFF
Sbjct: 781 EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840
Query: 836 KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAE 895
KIKPLLKSAETEKEMATMKEEFQK KDELAKSEAKRKELEEK+VTL++EKNDLQLQVQAE
Sbjct: 841 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900
Query: 896 SENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 955
+E L DAEERCDQLIK K QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI
Sbjct: 901 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960
Query: 956 DDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEE 1015
DDLELTLAKVEKEKHATENKVKNLTEE++GLDETIAKLT+EKKALQEAHQQ LDDLQAEE
Sbjct: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020
Query: 1016 DKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQ 1075
DKVN+L K K KLEQQV+DLE SLEQEKKLR+DLER KRKLEGDLKLAQESI+D+EN+KQ
Sbjct: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080
Query: 1076 QLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEK 1135
QLDE+LKKK+FE LQSK+EDEQ LG+Q QKKIKELQARIEELEEEIEAERA+RAK EK
Sbjct: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140
Query: 1136 QRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRK 1195
QRSD +RELEE+SERLEEAGG TS QIE+NKKREAEF K+RRDLEEATLQHEA A LRK
Sbjct: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200
Query: 1196 KHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLED 1255
KHADSVAELGEQIDNLQRVKQKLEKEKSE K+EIDDL+S++E+VSK+K NLEK+CRTLED
Sbjct: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260
Query: 1256 QLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEE 1315
QLSE + K EE QR +++LT Q+ RLQTE+GE SRQL+EKE++VSQLSR KQAFTQQ EE
Sbjct: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320
Query: 1316 LKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTK 1375
LKRQLEEE KAKNALAHALQSSRHDCDLLREQYEEEQE KAELQRALSKAN+EVAQWRTK
Sbjct: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380
Query: 1376 YETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVER 1435
YETDAIQRTEELEEAKKKLAQRLQ +EE VEAVNAKCASLEKTKQRLQ EVEDLM+DVER
Sbjct: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440
Query: 1436 ANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQ 1495
N+ AALDKKQRNFDK+LAEWK KCEE+ AELEAS KE+RSL TELFK+KNAYEE+LDQ
Sbjct: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500
Query: 1496 LETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHE 1555
LET+KRENKNL+QEI+DLTEQIAE GK IHELEK +KQ+E EK ++Q ALEEAEA+LEHE
Sbjct: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560
Query: 1556 EAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRL 1615
E KILRIQLEL QVKSE+DRKIAEKDEEI+QLKRN+ R VE+MQS LDAE+RSRN+AIRL
Sbjct: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620
Query: 1616 KKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIV 1675
KKKMEGDLNE+EIQL+HANR AAE L++ R+ QG LKDTQ+HLDDALR QEDLKEQLA+V
Sbjct: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680
Query: 1676 ERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDL 1735
ERRANLLQAE+EELRATLEQTER+RK+AEQELLD++ERVQLLHTQNTSLI+TKKKLETD+
Sbjct: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740
Query: 1736 MQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1795
Q+Q E+ED ++ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ
Sbjct: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800
Query: 1796 HRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQS 1855
RLDEAEQLALKGGKKQIQKLE R+RELE E+E EQK+N E+VKGLRK+ERRVKELTYQ+
Sbjct: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860
Query: 1856 EEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAE 1915
EEDRKN+LRLQDLVDKLQ KVKSYKRQAEEA+EQ+N +L KFRK QHELEEAEERADIAE
Sbjct: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920
Query: 1916 SQVNKLRAKTRD 1927
SQVNKLR K+R+
Sbjct: 1921 SQVNKLRVKSRE 1932
Score = 224 bits (571), Expect = 6e-58
Identities = 241/988 (24%), Positives = 448/988 (45%), Gaps = 150/988 (15%)
Query: 844 AETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAES------- 896
A+ KE ++E Q+T D+L E K L + + L Q+ +DL+ ++ E
Sbjct: 996 AKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLE 1055
Query: 897 --------------ENLLDAE---ERCDQLIKAK------------------FQLEAKIK 921
E+++D E ++ D+ +K K QL+ KIK
Sbjct: 1056 RAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIK 1115
Query: 922 EVTERAED-EEEINAELTAKKRKLEDECSELKKDIDDLE--------LTLAKVE--KEKH 970
E+ R E+ EEEI AE A + K E + S+L ++++++ T A++E K++
Sbjct: 1116 ELQARIEELEEEIEAE-RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKRE 1174
Query: 971 ATENKVKNLTEELSGLDETIAKLTREKKALQEAHQ-QALDDLQAEEDKVNSLNKTKSKLE 1029
A K++ EE + E A R+K A A + +D+LQ + K L K KS+++
Sbjct: 1175 AEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK---LEKEKSEMK 1231
Query: 1030 QQVEDLESSLEQEKKLRVDLERNKRKLE---GDLKLAQESILDLENDKQQLDERLKKKDF 1086
+++DL S++E K + +LE+ R LE +LK +E L ND RL+ +
Sbjct: 1232 MEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESG 1291
Query: 1087 EYCQLQSKVEDEQTLGLQFQKKIKELQARIEEL----EEEIEAERATRAKTEKQRSD--- 1139
E+ + ++++++ L Q + + +IEEL EEEI+A+ A + R D
Sbjct: 1292 EFSR---QLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDL 1348
Query: 1140 ----YARELEELSERLEEAGGVTSTQI-ELNKKREAEFLKLRRDLEEATLQHEAMVAALR 1194
Y E E +E L+ A +T++ + K E + ++ +LEEA +
Sbjct: 1349 LREQYEEEQESKAE-LQRALSKANTEVAQWRTKYETDAIQRTEELEEA-----------K 1396
Query: 1195 KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLE 1254
KK A + E ++ + LEK K + E++DL +E + + A L+K R +
Sbjct: 1397 KKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFD 1456
Query: 1255 DQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTE 1314
L+E + K EE L + L TE ++ EE + L R + Q+
Sbjct: 1457 KILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEIS 1516
Query: 1315 ELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS------- 1367
+L Q+ E K H+ + +++Q E+E K ELQ AL +A +
Sbjct: 1517 DLTEQIAEGGKRI-----------HELEKIKKQVEQE---KCELQAALEEAEASLEHEEG 1562
Query: 1368 -------EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQ 1420
E+ Q +++ + ++ EE+++ K+ + ++ + ++A + K+
Sbjct: 1563 KILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1622
Query: 1421 RLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLST 1480
+++G++ ++ + + AN +AA + RN +L + + +++ E LKE ++
Sbjct: 1623 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQE-DLKEQLAMVE 1681
Query: 1481 ELFKLKNA-YEEALDQLETVKRENKNLEQEIADLTEQI----AENGKTIHELEKSRKQIE 1535
L A EE LE +R K EQE+ D +E++ +N I+ +K I
Sbjct: 1682 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1741
Query: 1536 LEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTV 1595
+ +++ L+EA A E + I + ++K E D +E++K+N ++TV
Sbjct: 1742 QMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSA-----HLERMKKNMEQTV 1796
Query: 1596 ETMQSALD-AEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDT 1654
+ +Q LD AE + + +K+E + E+E ++ ++ AE +K LR + ++K+
Sbjct: 1797 KDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKEL 1856
Query: 1655 QLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTE--------RARKLAEQE 1706
+ +ED K L + + + LQA+V+ + E+ E + RKL + E
Sbjct: 1857 ------TYQTEEDRKNILRL-QDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKL-QHE 1908
Query: 1707 LLDSNERVQLLHTQNTSL------IHTK 1728
L ++ ER + +Q L +HTK
Sbjct: 1909 LEEAEERADIAESQVNKLRVKSREVHTK 1936
Score = 82.0 bits (201), Expect = 5e-15
Identities = 79/341 (23%), Positives = 155/341 (45%), Gaps = 38/341 (11%)
Query: 1636 QAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVE-ELRATLE 1694
++AET K + +++ + + + L + +++L+E++ + + N LQ +V+ E +
Sbjct: 847 KSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906
Query: 1695 QTERARKLA------EQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRD 1748
ER +L E ++ + ER + N L K+KLE + +L+ +++D
Sbjct: 907 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 966
Query: 1749 ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE----QTVKDLQHRLDEAEQL 1804
E++ + EE+ +T A L + KK L+ QT+ DLQ D+ L
Sbjct: 967 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1026
Query: 1805 A------------LKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELT 1852
L+G +Q +KL + + +LEG+ K ES+ + ++++ E
Sbjct: 1027 TKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKL 1086
Query: 1853 YQSEEDRKNV-LRLQD---LVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQ------- 1901
+ E + N+ +++D L +LQ K+K + + EE +E+ A KA+
Sbjct: 1087 KKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS 1146
Query: 1902 HELEEAEERADIA----ESQVNKLRAKTRDFTSSRMVVHES 1938
ELEE ER + A +Q+ + + +F R + E+
Sbjct: 1147 RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1187
Score = 42.7 bits (99), Expect = 0.003
Identities = 29/130 (22%), Positives = 61/130 (46%), Gaps = 7/130 (5%)
Query: 847 EKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERC 906
+K++ ++ ++ + E+ + + E + L + +L Q + + +N+L ++
Sbjct: 1815 KKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLV 1874
Query: 907 DQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 966
D+L +AK+K +AE+ EE + AK RKL+ E E ++ D E + K+
Sbjct: 1875 DKL-------QAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLR 1927
Query: 967 KEKHATENKV 976
+ KV
Sbjct: 1928 VKSREVHTKV 1937
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 3231 bits (8378), Expect = 0.0
Identities = 1639/1932 (84%), Positives = 1788/1932 (92%), Gaps = 5/1932 (0%)
Query: 1 MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKV 60
MSSD+E+ VFG AAPFLRKSE+ERIEAQN+PFDAKT FV + KE + KG I+S + GKV
Sbjct: 1 MSSDSELAVFGEAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKV 60
Query: 61 TVETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSG 120
TV+TE TL VK + V+ MNPPK+D+IEDMAM+THL+EPAVLYNLK+RY +WMIYTYSG
Sbjct: 61 TVKTEGGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
Query: 121 LFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
LFCVTVNPYKWLPVY PEVV YRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
Sbjct: 121 LFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
Query: 181 SGAGKTVNTKRVIQYFATIAATGDLAKKK--DSKMKGTLEDQIISANPLLEAFGNAKTVR 238
SGAGKTVNTKRVIQYFATIA TG+ K++ K++GTLEDQIISANPLLEAFGNAKTVR
Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVR 240
Query: 239 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL 298
NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRV FQLKAERSYHIFYQI SNKKPEL
Sbjct: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPEL 300
Query: 299 IELLLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVM 358
IE+LLITTNPYDYPF+SQGEI VASIDD EEL+ATDSAIDILGFT EEK +YKLTGAVM
Sbjct: 301 IEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVM 360
Query: 359 HYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTV 418
HYGN+KFKQKQREEQAEPDGTEVADK AYL LNS+DLLKALC+PRVKVGNEYVTKGQTV
Sbjct: 361 HYGNLKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420
Query: 419 DQVHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLC 478
+QV +AV AL+K+VYEK+FLWMV RINQQLDTK PRQ+FIGVLDIAGFEIF++NSLEQLC
Sbjct: 421 EQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
Query: 479 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 538
INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
Query: 539 CMFPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKN 598
CMFPKATDTSFKNKLYDQHLGKS NFQKPKVVKG+AEAHF+LIHYAG VDY+++GWLEKN
Sbjct: 541 CMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKN 600
Query: 599 KDPLNETVVGLYQKSSNRLLAHLYATFATAD---ADSGKKKVAKKKGSSFQTVSALFREN 655
KDPLNETVVGLYQKS+ + LA L++ TA+ A G KK KKKGSSFQTVSALFREN
Sbjct: 601 KDPLNETVVGLYQKSAMKTLAQLFSGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFREN 660
Query: 656 LNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRIL 715
LNKLM+NLR+THPHFVRCIIPNETKTPGAMEH LVLHQLRCNGVLEGIRICRKGFP+RIL
Sbjct: 661 LNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRIL 720
Query: 716 YGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLE 775
Y DFKQRY+VLNASAIPEGQFIDSKKA EKLLASIDIDHTQYKFGHTKVFFKAGLLG LE
Sbjct: 721 YADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLE 780
Query: 776 EMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFF 835
EMRDD+LA+LITRTQA CRGFL RVE+Q+MV+RRE+IFCIQYNIRSFMNVKHWPWMKLFF
Sbjct: 781 EMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFF 840
Query: 836 KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAE 895
KIKPLLKSAETEKEMATMKEEFQK KDELAKSEAKRKELEEK+VTL++EKNDLQLQVQAE
Sbjct: 841 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900
Query: 896 SENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 955
+E L DAEERCDQLIK K QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI
Sbjct: 901 AEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960
Query: 956 DDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEE 1015
DDLELTLAKVEKEKHATENKVKNLTEE++GLDETIAKLT+EKKALQEAHQQ LDDLQAEE
Sbjct: 961 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020
Query: 1016 DKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQ 1075
DKVN+L K K KLEQQV+DLE SLEQEKKLR+DLER KRKLEGDLKLAQESI+D+EN+KQ
Sbjct: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080
Query: 1076 QLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEK 1135
QLDE+LKKK+FE LQSK+EDEQ LG+Q QKKIKELQARIEELEEEIEAERA+RAK EK
Sbjct: 1081 QLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEK 1140
Query: 1136 QRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRK 1195
QRSD +RELEE+SERLEEAGG TS QIE+NKKREAEF K+RRDLEEATLQHEA A LRK
Sbjct: 1141 QRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRK 1200
Query: 1196 KHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLED 1255
KHADSVAELGEQIDNLQRVKQKLEKEKSE K+EIDDL+S++E+VSK+K NLEK+CRTLED
Sbjct: 1201 KHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLED 1260
Query: 1256 QLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEE 1315
QLSE + K EE QR +++LT Q+ RLQTE+GE SRQL+EKE++VSQLSR KQAFTQQ EE
Sbjct: 1261 QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEE 1320
Query: 1316 LKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTK 1375
LKRQLEEE KAKNALAHALQSSRHDCDLLREQYEEEQE KAELQRALSKAN+EVAQWRTK
Sbjct: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTK 1380
Query: 1376 YETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVER 1435
YETDAIQRTEELEEAKKKLAQRLQ +EE VEAVNAKCASLEKTKQRLQ EVEDLM+DVER
Sbjct: 1381 YETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVER 1440
Query: 1436 ANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQ 1495
N+ AALDKKQRNFDK+LAEWK KCEE+ AELEAS KE+RSL TELFK+KNAYEE+LDQ
Sbjct: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500
Query: 1496 LETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHE 1555
LET+KRENKNL+QEI+DLTEQIAE GK IHELEK +KQ+E EK ++Q ALEEAEA+LEHE
Sbjct: 1501 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE 1560
Query: 1556 EAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRL 1615
E KILRIQLEL QVKSE+DRKIAEKDEEI+QLKRN+ R VE+MQS LDAE+RSRN+AIRL
Sbjct: 1561 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRL 1620
Query: 1616 KKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIV 1675
KKKMEGDLNE+EIQL+HANR AAE L++ R+ QG LKDTQ+HLDDALR QEDLKEQLA+V
Sbjct: 1621 KKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMV 1680
Query: 1676 ERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDL 1735
ERRANLLQAE+EELRATLEQTER+RK+AEQELLD++ERVQLLHTQNTSLI+TKKKLETD+
Sbjct: 1681 ERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740
Query: 1736 MQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1795
Q+Q E+ED ++ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ
Sbjct: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800
Query: 1796 HRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQS 1855
RLDEAEQLALKGGKKQIQKLE R+RELE E+E EQK+N E+VKGLRK+ERRVKELTYQ+
Sbjct: 1801 LRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQT 1860
Query: 1856 EEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAE 1915
EEDRKN+LRLQDLVDKLQ KVKSYKRQAEEA+EQ+N +L KFRK QHELEEAEERADIAE
Sbjct: 1861 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAE 1920
Query: 1916 SQVNKLRAKTRD 1927
SQVNKLR K+R+
Sbjct: 1921 SQVNKLRVKSRE 1932
Score = 224 bits (571), Expect = 6e-58
Identities = 241/988 (24%), Positives = 448/988 (45%), Gaps = 150/988 (15%)
Query: 844 AETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAES------- 896
A+ KE ++E Q+T D+L E K L + + L Q+ +DL+ ++ E
Sbjct: 996 AKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLE 1055
Query: 897 --------------ENLLDAE---ERCDQLIKAK------------------FQLEAKIK 921
E+++D E ++ D+ +K K QL+ KIK
Sbjct: 1056 RAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIK 1115
Query: 922 EVTERAED-EEEINAELTAKKRKLEDECSELKKDIDDLE--------LTLAKVE--KEKH 970
E+ R E+ EEEI AE A + K E + S+L ++++++ T A++E K++
Sbjct: 1116 ELQARIEELEEEIEAE-RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKRE 1174
Query: 971 ATENKVKNLTEELSGLDETIAKLTREKKALQEAHQ-QALDDLQAEEDKVNSLNKTKSKLE 1029
A K++ EE + E A R+K A A + +D+LQ + K L K KS+++
Sbjct: 1175 AEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK---LEKEKSEMK 1231
Query: 1030 QQVEDLESSLEQEKKLRVDLERNKRKLE---GDLKLAQESILDLENDKQQLDERLKKKDF 1086
+++DL S++E K + +LE+ R LE +LK +E L ND RL+ +
Sbjct: 1232 MEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESG 1291
Query: 1087 EYCQLQSKVEDEQTLGLQFQKKIKELQARIEEL----EEEIEAERATRAKTEKQRSD--- 1139
E+ + ++++++ L Q + + +IEEL EEEI+A+ A + R D
Sbjct: 1292 EFSR---QLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDL 1348
Query: 1140 ----YARELEELSERLEEAGGVTSTQI-ELNKKREAEFLKLRRDLEEATLQHEAMVAALR 1194
Y E E +E L+ A +T++ + K E + ++ +LEEA +
Sbjct: 1349 LREQYEEEQESKAE-LQRALSKANTEVAQWRTKYETDAIQRTEELEEA-----------K 1396
Query: 1195 KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLE 1254
KK A + E ++ + LEK K + E++DL +E + + A L+K R +
Sbjct: 1397 KKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFD 1456
Query: 1255 DQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTE 1314
L+E + K EE L + L TE ++ EE + L R + Q+
Sbjct: 1457 KILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEIS 1516
Query: 1315 ELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS------- 1367
+L Q+ E K H+ + +++Q E+E K ELQ AL +A +
Sbjct: 1517 DLTEQIAEGGKRI-----------HELEKIKKQVEQE---KCELQAALEEAEASLEHEEG 1562
Query: 1368 -------EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQ 1420
E+ Q +++ + ++ EE+++ K+ + ++ + ++A + K+
Sbjct: 1563 KILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKK 1622
Query: 1421 RLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLST 1480
+++G++ ++ + + AN +AA + RN +L + + +++ E LKE ++
Sbjct: 1623 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQE-DLKEQLAMVE 1681
Query: 1481 ELFKLKNA-YEEALDQLETVKRENKNLEQEIADLTEQI----AENGKTIHELEKSRKQIE 1535
L A EE LE +R K EQE+ D +E++ +N I+ +K I
Sbjct: 1682 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1741
Query: 1536 LEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTV 1595
+ +++ L+EA A E + I + ++K E D +E++K+N ++TV
Sbjct: 1742 QMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSA-----HLERMKKNMEQTV 1796
Query: 1596 ETMQSALD-AEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDT 1654
+ +Q LD AE + + +K+E + E+E ++ ++ AE +K LR + ++K+
Sbjct: 1797 KDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKEL 1856
Query: 1655 QLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTE--------RARKLAEQE 1706
+ +ED K L + + + LQA+V+ + E+ E + RKL + E
Sbjct: 1857 ------TYQTEEDRKNILRL-QDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKL-QHE 1908
Query: 1707 LLDSNERVQLLHTQNTSL------IHTK 1728
L ++ ER + +Q L +HTK
Sbjct: 1909 LEEAEERADIAESQVNKLRVKSREVHTK 1936
Score = 82.0 bits (201), Expect = 5e-15
Identities = 79/341 (23%), Positives = 155/341 (45%), Gaps = 38/341 (11%)
Query: 1636 QAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVE-ELRATLE 1694
++AET K + +++ + + + L + +++L+E++ + + N LQ +V+ E +
Sbjct: 847 KSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906
Query: 1695 QTERARKLA------EQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRD 1748
ER +L E ++ + ER + N L K+KLE + +L+ +++D
Sbjct: 907 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 966
Query: 1749 ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE----QTVKDLQHRLDEAEQL 1804
E++ + EE+ +T A L + KK L+ QT+ DLQ D+ L
Sbjct: 967 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1026
Query: 1805 A------------LKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELT 1852
L+G +Q +KL + + +LEG+ K ES+ + ++++ E
Sbjct: 1027 TKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKL 1086
Query: 1853 YQSEEDRKNV-LRLQD---LVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQ------- 1901
+ E + N+ +++D L +LQ K+K + + EE +E+ A KA+
Sbjct: 1087 KKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS 1146
Query: 1902 HELEEAEERADIA----ESQVNKLRAKTRDFTSSRMVVHES 1938
ELEE ER + A +Q+ + + +F R + E+
Sbjct: 1147 RELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1187
Score = 42.7 bits (99), Expect = 0.003
Identities = 29/130 (22%), Positives = 61/130 (46%), Gaps = 7/130 (5%)
Query: 847 EKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERC 906
+K++ ++ ++ + E+ + + E + L + +L Q + + +N+L ++
Sbjct: 1815 KKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLV 1874
Query: 907 DQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 966
D+L +AK+K +AE+ EE + AK RKL+ E E ++ D E + K+
Sbjct: 1875 DKL-------QAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLR 1927
Query: 967 KEKHATENKV 976
+ KV
Sbjct: 1928 VKSREVHTKV 1937
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 3220 bits (8348), Expect = 0.0
Identities = 1627/1931 (84%), Positives = 1792/1931 (92%), Gaps = 5/1931 (0%)
Query: 1 MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKV 60
MSSD+EM +FG AAPFLRKSE+ERIEAQN+PFDAKT FVVD KE + K ++S + GKV
Sbjct: 1 MSSDSEMAIFGEAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKV 60
Query: 61 TVETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSG 120
T +TE T+ VK + V+ MNPPK+D+IEDMAM+THL+EPAVLYNLK+RY +WMIYTYSG
Sbjct: 61 TAKTEAGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
Query: 121 LFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
LFCVTVNPYKWLPVYN EVV YRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
Sbjct: 121 LFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
Query: 181 SGAGKTVNTKRVIQYFATIAATGDLAKKK--DSKMKGTLEDQIISANPLLEAFGNAKTVR 238
SGAGKTVNTKRVIQYFATIA TG+ K++ KM+GTLEDQIISANPLLEAFGNAKTVR
Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVR 240
Query: 239 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL 298
NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQI+SNKKP+L
Sbjct: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDL 300
Query: 299 IELLLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVM 358
IE+LLITTNPYDY F+SQGEI V SIDD EEL+ATDSAI+ILGFT +E+ +YKLTGAVM
Sbjct: 301 IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVM 360
Query: 359 HYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTV 418
HYGNMKFKQKQREEQAEPDGTEVADK AYL LNS+DLLKALC+PRVKVGNEYVTKGQTV
Sbjct: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTV 420
Query: 419 DQVHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLC 478
QV++AV AL+K+VY+K+FLWMVTRINQQLDTK PRQ+FIGVLDIAGFEIF++NSLEQLC
Sbjct: 421 QQVYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
Query: 479 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 538
INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 540
Query: 539 CMFPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKN 598
CMFPKATDTSFKNKLY+QHLGKSNNFQKPK KG+ EAHFSLIHYAGTVDY+++GWL+KN
Sbjct: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKN 600
Query: 599 KDPLNETVVGLYQKSSNRLLAHLY--ATFATADADSGKKKVAKKKGSSFQTVSALFRENL 656
KDPLNETVVGLYQKS+ + LA L+ AT A A+A GKK KKKGSSFQTVSALFRENL
Sbjct: 601 KDPLNETVVGLYQKSAMKTLALLFVGATGAEAEAGGGKKG-GKKKGSSFQTVSALFRENL 659
Query: 657 NKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILY 716
NKLM+NLR+THPHFVRCIIPNETKTPGAMEH LVLHQLRCNGVLEGIRICRKGFP+RILY
Sbjct: 660 NKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILY 719
Query: 717 GDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEE 776
DFKQRY+VLNASAIPEGQFIDSKKA EKLL SIDIDHTQYKFGHTKVFFKAGLLG LEE
Sbjct: 720 ADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEE 779
Query: 777 MRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFK 836
MRD++LA+LITRTQA+CRGFL RVE+QKMV+RRESIFCIQYN+R+FMNVKHWPWMKL+FK
Sbjct: 780 MRDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFK 839
Query: 837 IKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAES 896
IKPLLKSAETEKEMA MKEEF+KTK+ELAK+EAKRKELEEK+VTL+QEKNDLQLQVQAE+
Sbjct: 840 IKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEA 899
Query: 897 ENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID 956
++L DAEERCDQLIK K QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID
Sbjct: 900 DSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID 959
Query: 957 DLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEED 1016
DLELTLAKVEKEKHATENKVKNLTEE++GLDETIAKLT+EKKALQEAHQQ LDDLQAEED
Sbjct: 960 DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEED 1019
Query: 1017 KVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQ 1076
KVN+L K K KLEQQV+DLE SLEQEKK+R+DLER KRKLEGDLKLAQES +D+ENDKQQ
Sbjct: 1020 KVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQ 1079
Query: 1077 LDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQ 1136
LDE+LKKK+FE LQSK+EDEQ LG+Q QKKIKELQARIEELEEEIEAERA+RAK EKQ
Sbjct: 1080 LDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1139
Query: 1137 RSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKK 1196
RSD +RELEE+SERLEEAGG TS QIE+NKKREAEF K+RRDLEEATLQHEA A LRKK
Sbjct: 1140 RSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKK 1199
Query: 1197 HADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQ 1256
HADSVAELGEQIDNLQRVKQKLEKEKSE K+EIDDL+S+ME+VSK+K NLEK+CR LEDQ
Sbjct: 1200 HADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQ 1259
Query: 1257 LSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEEL 1316
LSE + K EE QR +++LT Q++RLQTE+GE SRQL+EK+++VSQLSR KQAFTQQ EEL
Sbjct: 1260 LSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEEL 1319
Query: 1317 KRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKY 1376
KRQLEEE KAK+ALAHALQSSRHDCDLLREQYEEEQE KAELQRA+SKANSEVAQWRTKY
Sbjct: 1320 KRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKY 1379
Query: 1377 ETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERA 1436
ETDAIQRTEELEEAKKKLAQRLQD+EE VEAVNAKCASLEKTKQRLQ EVEDLM+DVER
Sbjct: 1380 ETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERT 1439
Query: 1437 NSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQL 1496
N+ AALDKKQRNFDK+LAEWK KCEE+ AELEAS KESRSLSTELFK+KNAYEE+LDQL
Sbjct: 1440 NAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQL 1499
Query: 1497 ETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEE 1556
ET+KRENKNL+QEI+DLTEQIAE GK IHELEK +KQ+E EK+++Q ALEEAEA+LEHEE
Sbjct: 1500 ETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEE 1559
Query: 1557 AKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLK 1616
KILRIQLEL QVKSE+DRKIAEKDEEI+Q+KRN+ R VE+MQS LDAE+RSRN+AIRLK
Sbjct: 1560 GKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLK 1619
Query: 1617 KKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVE 1676
KKMEGDLNE+EIQL+HANR AAE L++ R+ Q LKDTQLHLDDALR QEDLKEQLA+VE
Sbjct: 1620 KKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVE 1679
Query: 1677 RRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLM 1736
RRANLLQAE+EELRATLEQTER+RK+AEQELLD++ERVQLLHTQNTSLI+TKKKLETD+
Sbjct: 1680 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1739
Query: 1737 QLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1796
Q+Q E+ED ++ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH
Sbjct: 1740 QIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1799
Query: 1797 RLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSE 1856
RLDEAEQLALKGGKKQIQKLE R+RELE E+E EQK+N E+VKGLRK+ER+VKELTYQ+E
Sbjct: 1800 RLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTE 1859
Query: 1857 EDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAES 1916
EDRKN+LRLQDLVDKLQ KVKSYKRQAEEA+EQ+N +L+KFR+ QHELEEAEERADIAES
Sbjct: 1860 EDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAES 1919
Query: 1917 QVNKLRAKTRD 1927
QVNKLR K+R+
Sbjct: 1920 QVNKLRVKSRE 1930
Score = 228 bits (581), Expect = 4e-59
Identities = 220/964 (22%), Positives = 432/964 (44%), Gaps = 110/964 (11%)
Query: 844 AETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAE 903
A+ KE ++E Q+T D+L E K L + + L Q+ +DL+ ++ E + +D E
Sbjct: 994 AKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLE 1053
Query: 904 ------------------------ERCDQLIKAK------------------FQLEAKIK 921
++ D+ +K K QL+ KIK
Sbjct: 1054 RAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIK 1113
Query: 922 EVTERAED-EEEINAELTAKKRKLEDECSELKKDIDDLE--------LTLAKVE--KEKH 970
E+ R E+ EEEI AE A + K E + S+L ++++++ T A++E K++
Sbjct: 1114 ELQARIEELEEEIEAE-RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKRE 1172
Query: 971 ATENKVKNLTEELSGLDETIAKLTREKKALQEAHQ-QALDDLQAEEDKVNSLNKTKSKLE 1029
A K++ EE + E A R+K A A + +D+LQ + K L K KS+++
Sbjct: 1173 AEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK---LEKEKSEMK 1229
Query: 1030 QQVEDLESSLEQEKKLRVDLERNKRKLE---GDLKLAQESILDLENDKQQLDERLKKKDF 1086
+++DL S++E K + +LE+ R LE ++K +E L ND RL+ +
Sbjct: 1230 MEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESG 1289
Query: 1087 EYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEE 1146
EY + +++++ TL Q + + +IEEL+ ++E E ++ + +
Sbjct: 1290 EYSR---QLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDL 1346
Query: 1147 LSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGE 1206
L E+ EE + K +E + R E +Q + +KK A + + E
Sbjct: 1347 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1406
Query: 1207 QIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEE 1266
++ + LEK K + E++DL +E + + A L+K R + L+E + K EE
Sbjct: 1407 HVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEE 1466
Query: 1267 IQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKA 1326
L + L TE ++ EE + L R + Q+ +L Q+ E K
Sbjct: 1467 THAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKR 1526
Query: 1327 KNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS--------------EVAQW 1372
H+ + +++Q E+E K+ELQ AL +A + E+ Q
Sbjct: 1527 I-----------HELEKIKKQVEQE---KSELQAALEEAEASLEHEEGKILRIQLELNQV 1572
Query: 1373 RTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVD 1432
+++ + ++ EE+++ K+ + ++ + ++A + K++++G++ ++ +
Sbjct: 1573 KSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQ 1632
Query: 1433 VERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNA-YEE 1491
+ AN +AA + RN +L + + +++ E LKE ++ L A EE
Sbjct: 1633 LNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQE-DLKEQLAMVERRANLLQAEIEE 1691
Query: 1492 ALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAA 1551
LE +R K EQE+ D +E++ L ++K++E + + IQ +E+
Sbjct: 1692 LRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQE 1751
Query: 1552 LEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALD-AEVRSRN 1610
+ E K + + + E+ +K + +E++K+N ++TV+ +Q LD AE +
Sbjct: 1752 ARNAEEKAKKAITDAAMMAEEL-KKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALK 1810
Query: 1611 EAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKD----TQLHLDDALRGQE 1666
+ +K+E + E+E ++ ++ E +K LR + ++K+ T+ + LR Q+
Sbjct: 1811 GGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQD 1870
Query: 1667 ----------DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQL 1716
K Q E ++N+ ++ ++ LE+ E +AE ++ + +
Sbjct: 1871 LVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSRE 1930
Query: 1717 LHTQ 1720
+HT+
Sbjct: 1931 VHTK 1934
Score = 169 bits (427), Expect = 3e-41
Identities = 174/850 (20%), Positives = 363/850 (42%), Gaps = 125/850 (14%)
Query: 1108 KIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKK 1167
K E + + ++EE E + AKTE +R +ELEE L + Q++
Sbjct: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKR----KELEEKMVTLMQEKNDLQLQVQAEAD 900
Query: 1168 REAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQID-NLQRVKQKLEKEKSEFK 1226
A+ + L + +Q EA + + ++ D E+I+ L K+KLE E SE K
Sbjct: 901 SLADAEERCDQLIKTKIQLEAKIKEVTERAEDE-----EEINAELTAKKRKLEDECSELK 955
Query: 1227 LEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAG 1286
+IDDL ++ V K K E + L ++++ + ++++LT +K LQ
Sbjct: 956 KDIDDLELTLAKVEKEKHATENKVKNLTEEMAG-------LDETIAKLTKEKKALQEAHQ 1008
Query: 1287 ELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLRE 1346
+ L+ +E V+ L+++K QQ ++L+ LE+E K + L A + D L +E
Sbjct: 1009 QTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQE 1068
Query: 1347 QYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVE 1406
+ + K ++L+E KK + + ++E
Sbjct: 1069 STMDIENDK-----------------------------QQLDEKLKKKEFEMSGLQSKIE 1099
Query: 1407 AVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQA 1466
A L+K + LQ +E+L ++E + A +K++ + + L E + EE+
Sbjct: 1100 DEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG 1159
Query: 1467 ELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHE 1526
A ++ ++ E K++ EEA Q E L ++ AD +AE G+ I
Sbjct: 1160 ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAA---TLRKKHAD---SVAELGEQIDN 1213
Query: 1527 LEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQ 1586
L++ ++++E EK+++++ +++ + +E +++ K +++ ++++ +
Sbjct: 1214 LQRVKQKLEKEKSEMKMEIDDLASNME-----------TVSKAKGNLEKMCRALEDQLSE 1262
Query: 1587 LKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRS 1646
+K + + R N+ + +++ + E QL + ++ + ++
Sbjct: 1263 IKTKEEE-----------QQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQA 1311
Query: 1647 VQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQE 1706
Q+++ + L++ ++ + L L +LL+ + EE + + +RA A
Sbjct: 1312 FTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKA--- 1368
Query: 1707 LLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMM 1766
N+ + + K ETD +Q E+E+A + K + + DA
Sbjct: 1369 --------------NSEVAQWRTKYETDAIQRTEELEEAKK-------KLAQRLQDAEEH 1407
Query: 1767 AEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQ------IQKLETRI 1820
E + + A LE+ K+ L+ V+DL ++ KKQ + + + +
Sbjct: 1408 VEAVNAK---CASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKC 1464
Query: 1821 RELEFELEGEQKK----NTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQV-- 1874
E ELE QK+ +TE K YE + +L E++ + DL +++
Sbjct: 1465 EETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGG 1524
Query: 1875 ----KVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTS 1930
+++ K+Q E+ + A L +A+ LE E + + ++N+++++
Sbjct: 1525 KRIHELEKIKKQVEQEKSELQAAL---EEAEASLEHEEGKILRIQLELNQVKSEV----- 1576
Query: 1931 SRMVVHESEE 1940
R + + EE
Sbjct: 1577 DRKIAEKDEE 1586
Score = 38.9 bits (89), Expect = 0.049
Identities = 25/130 (19%), Positives = 62/130 (47%), Gaps = 7/130 (5%)
Query: 847 EKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERC 906
+K++ ++ ++ + E+ + + E + L ++ +L Q + + +N+L ++
Sbjct: 1813 KKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLV 1872
Query: 907 DQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 966
D+L +AK+K +AE+ EE + +K R+++ E E ++ D E + K+
Sbjct: 1873 DKL-------QAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLR 1925
Query: 967 KEKHATENKV 976
+ K+
Sbjct: 1926 VKSREVHTKI 1935
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 3196 bits (8286), Expect = 0.0
Identities = 1611/1930 (83%), Positives = 1788/1930 (92%), Gaps = 3/1930 (0%)
Query: 1 MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKV 60
MSSD+EM +FG AAPFLRKSEKERIEAQN+PFDAKT FVVD KE Y K ++S + GKV
Sbjct: 1 MSSDSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKV 60
Query: 61 TVETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSG 120
T +TE T+ VK + V++MNPPK+D+IEDMAM+THL+EPAVLYNLK+RY +WMIYTYSG
Sbjct: 61 TAKTEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
Query: 121 LFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
LFCVTVNPYKWLPVYNPEVV YRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE
Sbjct: 121 LFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
Query: 181 SGAGKTVNTKRVIQYFATIAATGDLAKKKDS--KMKGTLEDQIISANPLLEAFGNAKTVR 238
SGAGKTVNTKRVIQYFATIA TG+ K++ + KM+GTLEDQIISANPLLEAFGNAKTVR
Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVR 240
Query: 239 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL 298
NDNSSRFGKFIRIHFG TGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL
Sbjct: 241 NDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL 300
Query: 299 IELLLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVM 358
IE+LLITTNPYD+ F+SQGEI V SIDD EEL+ATDSA+DILGFT +EK +YKLTGAVM
Sbjct: 301 IEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVM 360
Query: 359 HYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTV 418
HYGNMKFKQKQREEQAEPDGTEVADK AYL LNS+DLLK+LC+PRVKVGNE+VTKGQTV
Sbjct: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTV 420
Query: 419 DQVHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLC 478
QV++AV AL+K++YEK+FLWMVTRINQQLDTK PRQ+FIGVLDIAGFEIF++NSLEQLC
Sbjct: 421 QQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLC 480
Query: 479 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEE 538
INFTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDLAACIELIEKPMGIFSILEEE
Sbjct: 481 INFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEE 540
Query: 539 CMFPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKN 598
CMFPKATDTSFKNKLY+QHLGKSNNFQKPK KG+ EAHFSL+HYAGTVDY+++GWL+KN
Sbjct: 541 CMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKN 600
Query: 599 KDPLNETVVGLYQKSSNRLLAHLYATFATADADSGK-KKVAKKKGSSFQTVSALFRENLN 657
KDPLNETVVGLYQKS+ + LA L++ TA+A+ G KK KKKGSSFQTVSALFRENLN
Sbjct: 601 KDPLNETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGSSFQTVSALFRENLN 660
Query: 658 KLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYG 717
KLM+NLR+THPHFVRCIIPNETKTPGAMEH LVLHQLRCNGVLEGIRICRKGFP+RILY
Sbjct: 661 KLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYA 720
Query: 718 DFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEM 777
DFKQRY+VLNASAIPEGQFIDSKKA EKLL SI+IDHTQYKFGHTKVFFKAGLLGTLEEM
Sbjct: 721 DFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEM 780
Query: 778 RDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKI 837
RD++LA+LITRTQA+CRGFLMRVEF+KM++RRESIFCIQYNIR+FMNVKHWPWMKL+FKI
Sbjct: 781 RDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKI 840
Query: 838 KPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESE 897
KPLLKSAETEKEMA MKEEF+KTK+ELAK+EAKRKELEEK+VTL+QEKNDLQLQVQAE++
Sbjct: 841 KPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEAD 900
Query: 898 NLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 957
L DAEERCDQLIK K QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD
Sbjct: 901 ALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 960
Query: 958 LELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDK 1017
LELTLAKVEKEKHATENKVKNLTEE++GLDETIAKLT+EKKALQEAHQQ LDDLQ EEDK
Sbjct: 961 LELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDK 1020
Query: 1018 VNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQL 1077
VN+L K K+KLEQQV+DLE SLEQEKKL +DLER KRKLEGDLKLAQES +D ENDKQQL
Sbjct: 1021 VNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQL 1080
Query: 1078 DERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQR 1137
+E+LKKK+FE LQ K+EDEQ L +Q QKKIKELQARIEELEEEIEAERA+RAK EKQR
Sbjct: 1081 NEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1140
Query: 1138 SDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKH 1197
SD +RELEE+SERLEEAGG TS QIE+NKKREAEF K+RRDLEE+TLQHEA AALRKKH
Sbjct: 1141 SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKH 1200
Query: 1198 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQL 1257
ADSVAELGEQID+LQRVKQKLEKEKSE K+EI+DL+S+ME+VSK+KAN EK+CRTLEDQL
Sbjct: 1201 ADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQL 1260
Query: 1258 SEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELK 1317
SE + K EE QR ++EL+ QK+RL TE+GE SRQL+EK+++VSQLSR KQAFTQQ EELK
Sbjct: 1261 SEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELK 1320
Query: 1318 RQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYE 1377
RQLEEE KAK+ LAHALQS+RHDCDLLREQYEEEQE KAELQR +SKANSEVAQWRTKYE
Sbjct: 1321 RQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYE 1380
Query: 1378 TDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERAN 1437
TDAIQRTEELEEAKKKLAQRLQD+EE VEAVN+KCASLEKTKQRLQ EVEDLM+DVER+N
Sbjct: 1381 TDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSN 1440
Query: 1438 SLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLE 1497
+ ALDKKQRNFDKVLAEWK K EE+QAELEAS KESRSLSTELFK+KNAYEE+LD LE
Sbjct: 1441 AACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLE 1500
Query: 1498 TVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEA 1557
T+KRENKNL+QEI+DLTEQIAE GK IHELEK +KQ++ EK+++Q +LEEAEA+LEHEE
Sbjct: 1501 TLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEG 1560
Query: 1558 KILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKK 1617
KILRIQLEL QVKSEIDRKIAEKDEE++QLKRN+ R VE+MQS LDAE+RSRN+A+R+KK
Sbjct: 1561 KILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKK 1620
Query: 1618 KMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVER 1677
KMEGDLNE+EIQL+HANRQAAE L++LR+ QG LKDTQLHLDDA+RGQ+DLKEQLA+VER
Sbjct: 1621 KMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVER 1680
Query: 1678 RANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQ 1737
RANL+QAEVEELRA+LE+TER RK+AEQELLD++ERVQLLHTQNTSLI+TKKKLETD+ Q
Sbjct: 1681 RANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1740
Query: 1738 LQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHR 1797
+Q E+ED ++ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQTVKDLQ R
Sbjct: 1741 IQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLR 1800
Query: 1798 LDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEE 1857
LDEAEQLALKGGKKQIQKLE R+RELE E+E EQK N E+VKGLRK+ERRVKELTYQ+EE
Sbjct: 1801 LDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEE 1860
Query: 1858 DRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQ 1917
DRKN+LRLQDLVDKLQ KVK+YKRQAEEA+EQ+N +L KFRK QHELEEA+ERADIAESQ
Sbjct: 1861 DRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQ 1920
Query: 1918 VNKLRAKTRD 1927
VNKLR K+R+
Sbjct: 1921 VNKLRVKSRE 1930
Score = 216 bits (550), Expect = 2e-55
Identities = 210/950 (22%), Positives = 419/950 (44%), Gaps = 82/950 (8%)
Query: 844 AETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAE 903
A+ KE ++E Q+T D+L E K L + L Q+ +DL+ ++ E + +D E
Sbjct: 994 AKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLE 1053
Query: 904 ------------------------ERCDQLIKAK------------------FQLEAKIK 921
++ ++ +K K QL+ KIK
Sbjct: 1054 RAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIK 1113
Query: 922 EVTERAED-EEEINAELTAKKRKLEDECSELKKDIDDLE--------LTLAKVE--KEKH 970
E+ R E+ EEEI AE A + K E + S+L ++++++ T A++E K++
Sbjct: 1114 ELQARIEELEEEIEAE-RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKRE 1172
Query: 971 ATENKVKNLTEELSGLDETIAKLTREKKALQEAHQ-QALDDLQAEEDKVNSLNKTKSKLE 1029
A K++ EE + E A R+K A A + +D LQ + K L K KS+L+
Sbjct: 1173 AEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQK---LEKEKSELK 1229
Query: 1030 QQVEDLESSLEQEKKLRVDLERNKRKLE---GDLKLAQESILDLENDKQQLDERLKKKDF 1086
++ DL S++E K + + E+ R LE ++K +E L N+ RL +
Sbjct: 1230 MEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESG 1289
Query: 1087 EYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEE 1146
E+ + +++++ + Q + + +IEEL+ ++E E ++ + +
Sbjct: 1290 EFSR---QLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDL 1346
Query: 1147 LSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGE 1206
L E+ EE + K +E + R E +Q + +KK A + + E
Sbjct: 1347 LREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1406
Query: 1207 QIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEE 1266
++ + LEK K + E++DL +E + + L+K R + L+E + K EE
Sbjct: 1407 HVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEE 1466
Query: 1267 IQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKA 1326
Q L + L TE ++ EE + L R + Q+ +L Q+ E K
Sbjct: 1467 TQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKH 1526
Query: 1327 KNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEE 1386
+ L + H+ L+ EE + + + + E+ Q +++ + ++ EE
Sbjct: 1527 IHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEE 1586
Query: 1387 LEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKK 1446
L++ K+ + ++ + ++A + K++++G++ ++ + + AN AA +
Sbjct: 1587 LDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRN 1646
Query: 1447 QRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNA-YEEALDQLETVKRENKN 1505
RN +L + + +++ + LKE ++ L A EE LE +R K
Sbjct: 1647 LRNTQGILKDTQLHLDDA-IRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKM 1705
Query: 1506 LEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLE 1565
EQE+ D +E++ L ++K++E + + IQ +E+ + E K + +
Sbjct: 1706 AEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITD 1765
Query: 1566 LTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALD-AEVRSRNEAIRLKKKMEGDLN 1624
+ E+ +K + +E++K+N ++TV+ +Q LD AE + + +K+E +
Sbjct: 1766 AAMMAEEL-KKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVR 1824
Query: 1625 EIEIQLSHANRQAAETLKHLRSVQGQLKD----TQLHLDDALRGQEDL----------KE 1670
E+E ++ + E +K LR + ++K+ T+ + LR Q+ + K
Sbjct: 1825 ELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKR 1884
Query: 1671 QLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQ 1720
Q E ++N+ A+ +L+ LE+ + +AE ++ + + +HT+
Sbjct: 1885 QAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSREVHTK 1934
Score = 85.1 bits (209), Expect = 6e-16
Identities = 86/346 (24%), Positives = 152/346 (43%), Gaps = 48/346 (13%)
Query: 1636 QAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVE-ELRATLE 1694
++AET K + +++ + + T+ L +++L+E++ + + N LQ +V+ E A +
Sbjct: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALAD 904
Query: 1695 QTERARKLA------EQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRD 1748
ER +L E ++ + ER + N L K+KLE + +L+ +++D
Sbjct: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
Query: 1749 ARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLE----QTVKDLQHRLDEAEQL 1804
E++ + EE+ +T A L + KK L+ QT+ DLQ D+ L
Sbjct: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTL 1024
Query: 1805 ALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVK---ELTYQSEEDRKN 1861
K KLE ++ +LE LE E+K + + RK E +K E T +E D++
Sbjct: 1025 T-----KAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQ 1079
Query: 1862 VLRL------------------QDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQ-- 1901
+ Q L +LQ K+K + + EE +E+ A KA+
Sbjct: 1080 LNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1139
Query: 1902 -----HELEEAEERADIA----ESQVNKLRAKTRDFTSSRMVVHES 1938
ELEE ER + A +Q+ + + +F R + ES
Sbjct: 1140 RSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEES 1185
Score = 50.8 bits (120), Expect = 1e-05
Identities = 45/195 (23%), Positives = 85/195 (43%), Gaps = 21/195 (10%)
Query: 842 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLD 901
K+ + + A M EE +K +D A E +K +E+ + DLQL++ + L
Sbjct: 1758 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTV-------KDLQLRLDEAEQLALK 1810
Query: 902 AEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 961
++ Q +LEA+++E+ E E++ N E RK E EL ++
Sbjct: 1811 GGKKQIQ------KLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKN 1864
Query: 962 LAKVEKEKHATENKVKNLTEELSGLDE----TIAKLTREKKALQEAHQQALDDLQAEEDK 1017
+ +++ + KVK + +E +AK + + L+EA ++A E +
Sbjct: 1865 ILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERA----DIAESQ 1920
Query: 1018 VNSLNKTKSKLEQQV 1032
VN L ++ +V
Sbjct: 1921 VNKLRVKSREVHTKV 1935
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 3070 bits (7960), Expect = 0.0
Identities = 1530/1936 (79%), Positives = 1748/1936 (90%), Gaps = 3/1936 (0%)
Query: 1 MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKV 60
MSSD EM +FG AAP+LRK EKERIEAQN+PFD+K CFV D+KE Y KG I++ ++ KV
Sbjct: 1 MSSDAEMAIFGEAAPYLRKPEKERIEAQNRPFDSKKACFVADNKEMYVKGMIQTRENDKV 60
Query: 61 TVETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSG 120
V+T D+R L + + V+ MNPPKFD+IEDMAM+THL+EPAVLYNLK+RY +WMIYTYSG
Sbjct: 61 IVKTLDDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSG 120
Query: 121 LFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGE 180
LFCVTVNPYKWLPVY PEVV YRGKKRQEAPPHIFSISDNAYQFMLTDR+NQSILITGE
Sbjct: 121 LFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGE 180
Query: 181 SGAGKTVNTKRVIQYFATIAATGDLAKK-KDSKMKGTLEDQIISANPLLEAFGNAKTVRN 239
SGAGKTVNTKRVIQYFATIA TGD K+ + KM+GTLEDQII ANPLLEAFGNAKTVRN
Sbjct: 181 SGAGKTVNTKRVIQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRN 240
Query: 240 DNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELI 299
DNSSRFGKFIRIHFG TGKLASADIETYLLEKSRVTFQL +ERSYHIFYQI+SNKKPELI
Sbjct: 241 DNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELI 300
Query: 300 ELLLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMH 359
+LLLI+TNP+D+PF+SQGE+ VASIDD+EELLATD+AIDILGF+ EEK G+YKLTGAVMH
Sbjct: 301 DLLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMH 360
Query: 360 YGNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVD 419
YGNMKFKQKQREEQAEPDGTEVADK YLMGLNS+++LK LC PRVKVGNEYVTKGQ V
Sbjct: 361 YGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQ 420
Query: 420 QVHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCI 479
QV ++V AL+K+VYEK+FLWMVTRINQQLDTK PRQ+FIGVLDIAGFEIF++NSLEQLCI
Sbjct: 421 QVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCI 480
Query: 480 NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEEC 539
NFTNEKLQQFFNHHMFVLEQEEYKKEGIEW FIDFGMDLAACIELIEKPMGIFSILEEEC
Sbjct: 481 NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEEC 540
Query: 540 MFPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNK 599
MFPKATDTSFKNKLYDQHLGKSNNFQKPK KG+AEAHFSL+HYAGTVDY+++GWL+KNK
Sbjct: 541 MFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNK 600
Query: 600 DPLNETVVGLYQKSSNRLLAHLYATFATADA--DSGKKKVAKKKGSSFQTVSALFRENLN 657
DPLNETVVGLYQKSS +LL+ L++ +A A+ G KK KKKGSSFQTVSA+FRENLN
Sbjct: 601 DPLNETVVGLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLN 660
Query: 658 KLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYG 717
KLM+NLR+THPHFVRC+IPNETKTPG M+H LV+HQLRCNGVLEGIRICRKGFP+RILY
Sbjct: 661 KLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYA 720
Query: 718 DFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEM 777
DFKQRYR+LNASAIPEGQFIDSK A EKLL SID+D Q++FG+TKVFFKAGLLG LEEM
Sbjct: 721 DFKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEM 780
Query: 778 RDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKI 837
RD++L L+T TQAVCRG+LMRVEF+KM++RR+SIFCIQYNIRSFMNVKHWPWM LFFKI
Sbjct: 781 RDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKI 840
Query: 838 KPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESE 897
KPLLKSAE EKEMATMKE+F++TK+ELA+SEA+RKELEEK+V+L+QEKNDLQLQVQ+E+E
Sbjct: 841 KPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETE 900
Query: 898 NLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 957
NL+DAEERC+ LIK+K LEAK+KE+TER E+EEE+N+EL AKKR LED+CS LK+DIDD
Sbjct: 901 NLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDD 960
Query: 958 LELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDK 1017
LELTL KVEKEKHATENKVKNL+EE++ L+E I+KLT+EKK+LQEAHQQ LDDLQ EEDK
Sbjct: 961 LELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDK 1020
Query: 1018 VNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQL 1077
VN L K +KLEQQ +DLE SLEQEKKLR DLER KRKLEGDLK++QESI+DLENDKQQ+
Sbjct: 1021 VNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQI 1080
Query: 1078 DERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQR 1137
+E+LKKK+FE QLQ+K++DEQ LQFQKKIKELQARIEELEEEIEAE RAK EKQR
Sbjct: 1081 EEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQR 1140
Query: 1138 SDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKH 1197
SD ARELEE+SERLEEA G TS QIE+NKKREAEF K+RRDLEEATLQHEA A LRKK
Sbjct: 1141 SDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQ 1200
Query: 1198 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQL 1257
ADSVAELGEQIDNLQRVKQKLEKEKSE K+EIDD++S++E++SKSK+N+E+ CRT+EDQ
Sbjct: 1201 ADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQF 1260
Query: 1258 SEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELK 1317
SE + K+E+ + + +L QK+RLQT+ GELS ++EEKES++SQL++SKQA TQQ EELK
Sbjct: 1261 SEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELK 1320
Query: 1318 RQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYE 1377
RQ+EEE KAKNA+AHALQSSRHDCDLLREQYEEEQE KAELQRALSKANSEVAQWRTKYE
Sbjct: 1321 RQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYE 1380
Query: 1378 TDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERAN 1437
TDAIQRTEELEEAKKKLAQRLQ++EE E N+KCASLEKTKQRLQGEVEDLM D+ER++
Sbjct: 1381 TDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSH 1440
Query: 1438 SLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLE 1497
+ A LDKKQRNFDKVLAEWK K +ESQAELEA+ KESRSLSTELFK++NAYEE +DQLE
Sbjct: 1441 TACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLE 1500
Query: 1498 TVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEA 1557
T++RENKNL++EI+DLTEQIAE GK + E EK++K +E EK+D+Q+ALEE E +LEHEE+
Sbjct: 1501 TLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEES 1560
Query: 1558 KILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKK 1617
KILR+QLEL+QVKSE+DRK+ EKDEEIEQLKRN QR E +QS LDAE+RSRN+A+RLKK
Sbjct: 1561 KILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKK 1620
Query: 1618 KMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVER 1677
KMEGDLNE+EIQL H+NRQ AET KHLR+VQGQLKD+QLHLDDALR EDLKEQLAIVER
Sbjct: 1621 KMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVER 1680
Query: 1678 RANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQ 1737
R LL E+EE++ LEQTER R+L+EQELLD+++RVQLLH+QNTSLI+TKKKLE D+ Q
Sbjct: 1681 RNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQ 1740
Query: 1738 LQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHR 1797
Q+EVE++ +++RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHR
Sbjct: 1741 CQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHR 1800
Query: 1798 LDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEE 1857
LDEAEQLALKGGKKQIQKLE R+RELE EL+ EQK+ E++KG KYER+VKE+TYQ+EE
Sbjct: 1801 LDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEE 1860
Query: 1858 DRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQ 1917
D KN+LRLQDLVDKLQ KVKSYKRQAEEA+EQAN L++ R+ QHELEEA ERADIAESQ
Sbjct: 1861 DHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQ 1920
Query: 1918 VNKLRAKTRDFTSSRM 1933
VNKLRAK+RD S +M
Sbjct: 1921 VNKLRAKSRDVGSQKM 1936
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 3054 bits (7917), Expect = 0.0
Identities = 1530/1939 (78%), Positives = 1745/1939 (89%), Gaps = 3/1939 (0%)
Query: 3 SDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKVTV 62
+D +M FG AA +LRKSEKER+EAQ +PFD +T CFV D KEE+ K KI S + GKV
Sbjct: 2 TDAQMADFGAAAQYLRKSEKERLEAQTRPFDIRTECFVPDDKEEFVKAKILSREGGKVIA 61
Query: 63 ETEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLF 122
ETE+ +T+ VK + V NPPKFD+IEDMAMLT L+EPAVL+NLK+RY +WMIYTYSGLF
Sbjct: 62 ETENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLF 121
Query: 123 CVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESG 182
CVTVNPYKWLPVYN EVV YRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESG
Sbjct: 122 CVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESG 181
Query: 183 AGKTVNTKRVIQYFATIAATGDLAKKKDSKM-KGTLEDQIISANPLLEAFGNAKTVRNDN 241
AGKTVNTKRVIQYFA+IAA GD KK ++ KGTLEDQII ANP LEAFGNAKTVRNDN
Sbjct: 182 AGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQANPALEAFGNAKTVRNDN 241
Query: 242 SSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIEL 301
SSRFGKFIRIHFG TGKLASADIETYLLEKSRV FQLKAER+YHIFYQILSNKKPEL+++
Sbjct: 242 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDM 301
Query: 302 LLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYG 361
LL+T NPYDY F+SQGE+ VASIDD+EEL+ATDSA D+LGFT EEK+G+YKLTGA+MHYG
Sbjct: 302 LLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYG 361
Query: 362 NMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQV 421
NMKFKQKQREEQAEPDGTE ADK+AYLMGLNS+DLLK LC PRVKVGNEYVTKGQ+V QV
Sbjct: 362 NMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQV 421
Query: 422 HHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINF 481
++++ AL+K+VYEK+F WMVTRIN L+TK PRQ+FIGVLDIAGFEIF++NS EQLCINF
Sbjct: 422 YYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINF 481
Query: 482 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMF 541
TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL ACI+LIEKPMGI SILEEECMF
Sbjct: 482 TNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMF 541
Query: 542 PKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDP 601
PKATD +FK KLYD HLGKSNNFQKP+ +KG+ EAHFSLIHYAGTVDY++ GWLEKNKDP
Sbjct: 542 PKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDP 601
Query: 602 LNETVVGLYQKSSNRLLAHLYATFATADA-DSGKKKVAKKKGSSFQTVSALFRENLNKLM 660
LNETVV LYQKSS +L+A L++++ATAD DSGK K KKKGSSFQTVSAL RENLNKLM
Sbjct: 602 LNETVVALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLM 661
Query: 661 SNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFK 720
+NLRTTHPHFVRCIIPNE K PG M++ LV+HQLRCNGVLEGIRICRKGFPNRILYGDF+
Sbjct: 662 TNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFR 721
Query: 721 QRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDD 780
QRYR+LN AIPEGQFIDS+K EKLL+S+DIDH QYKFGHTKVFFKAGLLG LEEMRD+
Sbjct: 722 QRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDE 781
Query: 781 RLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPL 840
RL+++ITR QA RG LMR+EF+K+V+RR+++ IQ+NIR+FM VK+WPWMKL+FKIKPL
Sbjct: 782 RLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPL 841
Query: 841 LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLL 900
LKSAETEKEMATMKEEF + K+ L KSEA+RKELEEK+V+L+QEKNDLQLQVQAE +NL
Sbjct: 842 LKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLN 901
Query: 901 DAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL 960
DAEERCDQLIK K QLEAK+KE+ ER EDEEE+NAELTAKKRKLEDECSELKKDIDDLEL
Sbjct: 902 DAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLEL 961
Query: 961 TLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNS 1020
TLAKVEKEKHATENKVKNLTEE++GLDE IAKLT+EKKALQEAHQQALDDLQ EEDKVNS
Sbjct: 962 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNS 1021
Query: 1021 LNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDER 1080
L+K+K KLEQQV+DLE SLEQEKK+R+DLER KRKLEGDLKL QESI+DLENDK QL+E+
Sbjct: 1022 LSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEK 1081
Query: 1081 LKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY 1140
LKKK+F+ Q SK+EDEQ L LQ QKK+KE QARIEELEEE+EAER RAK EK RSD
Sbjct: 1082 LKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDL 1141
Query: 1141 ARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADS 1200
+RELEE+SERLEEAGG TS QIE+NKKREAEF K+RRDLEEATLQHEA AALRKKHADS
Sbjct: 1142 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 1201
Query: 1201 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 1260
VAELGEQIDNLQRVKQKLEKEKSEFKLE+DD++S+ME + K+KANLEK+ RTLEDQ +E
Sbjct: 1202 VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEY 1261
Query: 1261 RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQL 1320
R K EE QRSL++ TTQ+++LQTE GEL+RQLEEKE+++SQL+R K ++TQQ E+LKRQL
Sbjct: 1262 RVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQL 1321
Query: 1321 EEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 1380
EEE KAKNALAHALQS+RHDCDLLREQYEEE E KAELQR LSKANSEVAQWRTKYETDA
Sbjct: 1322 EEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1381
Query: 1381 IQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLA 1440
IQRTEELEEAKKKLAQRLQD+EE VEAVNAKC+SLEKTK RLQ E+EDLMVDVER+N+ A
Sbjct: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAA 1441
Query: 1441 AALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVK 1500
AALDKKQRNFDK+LAEWK K EESQ+ELE+S KE+RSLSTELFKLKNAYEE+L+ LET K
Sbjct: 1442 AALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFK 1501
Query: 1501 RENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKIL 1560
RENKNL++EI+DLTEQ+ E GK +HELEK RKQ+E+EK ++Q ALEEAEA+LEHEE KIL
Sbjct: 1502 RENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKIL 1561
Query: 1561 RIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKME 1620
R QLE Q+K+EI+RK+AEKDEE+EQ KRN+QR V+++Q++LDAE RSRNE +R+KKKME
Sbjct: 1562 RAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKME 1621
Query: 1621 GDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRAN 1680
GDLNE+EIQLSHANR AAE K ++S+Q LKDTQ+ LDDA+R +DLKE +AIVERR N
Sbjct: 1622 GDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNN 1681
Query: 1681 LLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQS 1740
LLQAE+EELRA +EQTER+RKLAEQEL++++ERVQLLH+QNTSLI+ KKK+E+DL QLQS
Sbjct: 1682 LLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQS 1741
Query: 1741 EVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE 1800
EVE+A ++ RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQT+KDLQHRLDE
Sbjct: 1742 EVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDE 1801
Query: 1801 AEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRK 1860
AEQ+ALKGGKKQ+QKLE R+RELE ELE EQK+N ESVKG+RK ERR+KELTYQ+EED+K
Sbjct: 1802 AEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKK 1861
Query: 1861 NVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNK 1920
N+LRLQDLVDKLQ+KVK+YKRQAEEA+EQAN +L+KFRK QHEL+EAEERADIAESQVNK
Sbjct: 1862 NLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNK 1921
Query: 1921 LRAKTRDFTSSRMVVHESE 1939
LRAK+RD ++ +H+ E
Sbjct: 1922 LRAKSRDI-GAKQKMHDEE 1939
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 3040 bits (7882), Expect = 0.0
Identities = 1525/1924 (79%), Positives = 1728/1924 (89%)
Query: 4 DTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKVTVE 63
D+EM VFG AAP+LRKSEKER+EAQ +PFD K FV D K+E+ K KI S + GKVT E
Sbjct: 3 DSEMAVFGAAAPYLRKSEKERLEAQTRPFDLKKDVFVPDDKQEFVKAKIVSREGGKVTAE 62
Query: 64 TEDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLFC 123
TE +T+ VK + V NPPKFD+IEDMAMLT L+EPAVLYNLKDRY SWMIYTYSGLFC
Sbjct: 63 TEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFC 122
Query: 124 VTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGA 183
VTVNPYKWLPVY PEVV YRGKKR EAPPHIFSISDNAYQ+MLTDRENQSILITGESGA
Sbjct: 123 VTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGA 182
Query: 184 GKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSS 243
GKTVNTKRVIQYFA IAA GD +KK S KGTLEDQII ANP LEAFGNAKTVRNDNSS
Sbjct: 183 GKTVNTKRVIQYFAVIAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSS 242
Query: 244 RFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIELLL 303
RFGKFIRIHFG TGKLASADIETYLLEKSRV FQLKAER YHIFYQILSNKKPEL+++LL
Sbjct: 243 RFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLL 302
Query: 304 ITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNM 363
IT NPYDY FISQGE VASIDDAEEL+ATD+A D+LGFT EEK+ +YKLTGA+MH+GNM
Sbjct: 303 ITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNM 362
Query: 364 KFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHH 423
KFK KQREEQAEPDGTE ADK+AYLMGLNS+DLLK LC PRVKVGNEYVTKGQ V QV +
Sbjct: 363 KFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIY 422
Query: 424 AVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTN 483
A AL+K+VYE++F WMVTRIN L+TK PRQ+FIGVLDIAGFEIF++NS EQLCINFTN
Sbjct: 423 ATGALAKAVYERMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTN 482
Query: 484 EKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPK 543
EKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL ACI+LIEKPMGI SILEEECMFPK
Sbjct: 483 EKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPK 542
Query: 544 ATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLN 603
ATD +FK KL+D HLGKS NFQKP+ +KG+ EAHFSLIHYAG VDY++ GWL+KNKDPLN
Sbjct: 543 ATDMTFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLN 602
Query: 604 ETVVGLYQKSSNRLLAHLYATFATADADSGKKKVAKKKGSSFQTVSALFRENLNKLMSNL 663
ETVVGLYQKSS +LL+ L+A +A ADA K K KKGSSFQTVSAL RENLNKLM+NL
Sbjct: 603 ETVVGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNL 662
Query: 664 RTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRY 723
R+THPHFVRCIIPNETK+PG M++ LV+HQLRCNGVLEGIRICRKGFPNRILYGDF+QRY
Sbjct: 663 RSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRY 722
Query: 724 RVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLA 783
R+LN +AIPEGQFIDS+K EKLL+S+DIDH QYKFGHTKVFFKAGLLG LEEMRD+RL+
Sbjct: 723 RILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLS 782
Query: 784 KLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKS 843
++ITR QA RG L R+E++K+++RR+S+ IQ+NIR+FM VK+WPWMKL+FKIKPLLKS
Sbjct: 783 RIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKS 842
Query: 844 AETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAE 903
AE EKEMA+MKEEF + K+ L KSEA+RKELEEK+V+L+QEKNDLQLQVQAE +NL DAE
Sbjct: 843 AEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 902
Query: 904 ERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 963
ERCDQLIK K QLEAK+KE+ ER EDEEE+NAELTAKKRKLEDECSELK+DIDDLELTLA
Sbjct: 903 ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLA 962
Query: 964 KVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNK 1023
KVEKEKHATENKVKNLTEE++GLDE IAKLT+EKKALQEAHQQALDDLQAEEDKVN+L K
Sbjct: 963 KVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTK 1022
Query: 1024 TKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKK 1083
K KLEQQV+DLE SLEQEKK+R+DLER KRKLEGDLKL QESI+DLENDKQQLDERLKK
Sbjct: 1023 AKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKK 1082
Query: 1084 KDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARE 1143
KDFE L +++EDEQ LG Q QKK+KELQARIEELEEE+EAER RAK EK RSD +RE
Sbjct: 1083 KDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRE 1142
Query: 1144 LEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAE 1203
LEE+SERLEEAGG TS QIE+NKKREAEF K+RRDLEEATLQHEA AALRKKHADSVAE
Sbjct: 1143 LEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAE 1202
Query: 1204 LGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGK 1263
LGEQIDNLQRVKQKLEKEKSEFKLE+DD++S+ME + K+KANLEK+CRTLEDQ++E R K
Sbjct: 1203 LGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSK 1262
Query: 1264 NEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEE 1323
EE QRS+++LT+Q+++LQTE GELSRQL+EKE+++SQL+R K +TQQ E+LKRQLEEE
Sbjct: 1263 AEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEE 1322
Query: 1324 NKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQR 1383
KAKNALAHALQS+RHDCDLLREQYEEE E KAELQR LSKANSEVAQWRTKYETDAIQR
Sbjct: 1323 VKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR 1382
Query: 1384 TEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAAL 1443
TEELEEAKKKLAQRLQ++EE VEAVNAKC+SLEKTK RLQ E+EDLMVDVER+N+ AAAL
Sbjct: 1383 TEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL 1442
Query: 1444 DKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKREN 1503
DKKQRNFDK+LAEWK K EESQ+ELE+S KE+RSLSTELFKLKNAYEE+L+ LET KREN
Sbjct: 1443 DKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKREN 1502
Query: 1504 KNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQ 1563
KNL++EI+DLTEQ+ +GKTIHELEK RKQ+E EK ++Q ALEEAEA+LEHEE KILR Q
Sbjct: 1503 KNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQ 1562
Query: 1564 LELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDL 1623
LE Q+K+EI+RK+AEKDEE+EQ KRN+ R V+++Q++LDAE RSRNEA+R+KKKMEGDL
Sbjct: 1563 LEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDL 1622
Query: 1624 NEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQ 1683
NE+EIQLSHANR AAE K ++S+Q LKDTQ+ LDDA+R +DLKE +AIVERR NLLQ
Sbjct: 1623 NEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQ 1682
Query: 1684 AEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVE 1743
AE+EELRA +EQTER+RKLAEQEL++++ERVQLLH+QNTSLI+ KKK++ DL QLQ+EVE
Sbjct: 1683 AELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVE 1742
Query: 1744 DASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQ 1803
+A ++ RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN+EQT+KDLQHRLDEAEQ
Sbjct: 1743 EAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1802
Query: 1804 LALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVL 1863
+ALKGGKKQ+QKLE R+RELE ELE EQK+N ESVKG+RK ERR+KELTYQ+EEDRKN+L
Sbjct: 1803 IALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLL 1862
Query: 1864 RLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRA 1923
RLQDLVDKLQ+KVK+YKRQAEEA+EQAN +L+KFRK QHEL+EAEERADIAESQVNKLRA
Sbjct: 1863 RLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRA 1922
Query: 1924 KTRD 1927
K+RD
Sbjct: 1923 KSRD 1926
Score = 146 bits (368), Expect = 2e-34
Identities = 165/758 (21%), Positives = 331/758 (43%), Gaps = 83/758 (10%)
Query: 1196 KHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLED 1255
K A+ E+ + R+K+ LEK ++ K +L M S+ + K +L+ + +D
Sbjct: 841 KSAEREKEMASMKEEFTRLKEALEKSEARRK----ELEEKMVSLLQEKNDLQLQVQAEQD 896
Query: 1256 QLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEE 1315
L++A + +L K +L+ + E++ +LE++E + ++L+ K+ + E
Sbjct: 897 NLADA-------EERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSE 949
Query: 1316 LKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTK 1375
LKR +++ + LA ++ +H + + EE G E+ L+K + Q +
Sbjct: 950 LKRDIDD---LELTLAK-VEKEKHATENKVKNLTEEMAGLDEIIAKLTK-EKKALQEAHQ 1004
Query: 1376 YETDAIQRTEE----LEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMV 1431
D +Q E+ L +AK KL Q++ D E +E LE+ K++L+G+++
Sbjct: 1005 QALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQE 1064
Query: 1432 DVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEE 1491
+ + LD++ + D L + E+ QA K+ + L + +L+ E
Sbjct: 1065 SIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEA 1124
Query: 1492 ALDQLETVKRENKNLEQEIADLTEQIAE-NGKTIHELEKSRKQIELEKADIQLALEEAEA 1550
V++ +L +E+ +++E++ E G T ++E ++K+ E E ++ LEEA
Sbjct: 1125 ERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR-EAEFQKMRRDLEEA-- 1181
Query: 1551 ALEHEE-AKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSR 1609
L+HE A LR K D +AE E+I+ L+R Q+ L+ E
Sbjct: 1182 TLQHEATAAALR--------KKHAD-SVAELGEQIDNLQRVKQK--------LEKE---- 1220
Query: 1610 NEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLK 1669
K + + +L+++ + + A K R+++ Q+ + + ++ R DL
Sbjct: 1221 ------KSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLT 1274
Query: 1670 EQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKK 1729
Q A ++ L +++E A + Q R + Q+L D +++ +L H +
Sbjct: 1275 SQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQ 1334
Query: 1730 KLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQ 1789
D L+ + E+ + + KA ++ A K E D E LE+
Sbjct: 1335 SARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW--RTKYETDAIQRTEE----LEE 1388
Query: 1790 TVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEG---EQKKNTESVKGLRKYER 1846
K L RL EAE+ A++ + LE L+ E+E + +++ + L K +R
Sbjct: 1389 AKKKLAQRLQEAEE-AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR 1447
Query: 1847 RVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEE 1906
++ + ++ K + + + E + ++A + T+ K ++ EE
Sbjct: 1448 NFDKILAEWKQ-----------------KYEESQSELESSQKEARSLSTELFKLKNAYEE 1490
Query: 1907 AEERADIAESQVNKLRAKTRDFT----SSRMVVHESEE 1940
+ E + + + L+ + D T SS +HE E+
Sbjct: 1491 SLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 1528
Score = 66.2 bits (160), Expect = 3e-10
Identities = 74/308 (24%), Positives = 134/308 (43%), Gaps = 58/308 (18%)
Query: 843 SAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDA 902
+AE +K++ +++ + T+ +L + +L+E + +V+ +N+L +QAE E L
Sbjct: 1636 AAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKEN-IAIVERRNNL---LQAELEELRAV 1691
Query: 903 EERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTL 962
E+ ++ K E ++ E +ER + N L +K+K++ + S+L+ ++++
Sbjct: 1692 VEQTERSRKLA---EQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQEC 1748
Query: 963 AKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSL- 1021
E++ + EEL +T A L R KK ++ Q + DLQ D+ +
Sbjct: 1749 RNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME----QTIKDLQHRLDEAEQIA 1804
Query: 1022 ----NKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLK-LAQESILDLEN---- 1072
K KLE +V +LE+ LE E+K + + RK E +K L ++ D +N
Sbjct: 1805 LKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRL 1864
Query: 1073 ----DKQQL------------------------------DERLKKKDFEYCQ---LQSKV 1095
DK QL DE ++ D Q L++K
Sbjct: 1865 QDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKS 1924
Query: 1096 EDEQTLGL 1103
D T GL
Sbjct: 1925 RDIGTKGL 1932
Score = 37.4 bits (85), Expect = 0.14
Identities = 42/177 (23%), Positives = 74/177 (41%), Gaps = 44/177 (24%)
Query: 840 LLKSAETEKEMATMKEEFQKT-------------------KDELAKSEAKRKELEEKLVT 880
L K +T + MK+ ++T K +L K EA+ +ELE +L
Sbjct: 1769 LKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEA 1828
Query: 881 LVQEKN---------------DLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTE 925
Q++N +L Q + + +NLL ++ D+L + K+K
Sbjct: 1829 -EQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKL-------QLKVKAYKR 1880
Query: 926 RAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 982
+AE+ EE +K RK++ E E ++ D E + K+ + + + K L EE
Sbjct: 1881 QAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAK--SRDIGTKGLNEE 1935
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 2586 bits (6703), Expect = 0.0
Identities = 1304/1932 (67%), Positives = 1607/1932 (83%), Gaps = 11/1932 (0%)
Query: 6 EMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKS-SQDGKVTVET 64
++ G +A +LR+ +E + P+D K +V D ++ Y + ++KS + G+VTVET
Sbjct: 45 DVSELGESARYLRQGYQEMTKVHTIPWDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVET 104
Query: 65 EDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCV 124
+D + L+V+ ++ MNPP+FD +EDMAM+THLNE +VL+NL+ RY WMIYTYSGLFCV
Sbjct: 105 KDQKVLMVREAELQPMNPPRFDLLEDMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCV 164
Query: 125 TVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 184
T+NPYKWLPVY VV Y+GK+R ++PPHI++++DNAY ML +R+NQS+LITGESGAG
Sbjct: 165 TINPYKWLPVYTASVVAAYKGKRRSDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAG 224
Query: 185 KTVNTKRVIQYFATIAATGDLAKKKD----SKMKGTLEDQIISANPLLEAFGNAKTVRND 240
KTVNTKRVIQYFA +AA GD KK +K GTLEDQII ANP +EAFGNAKT+RND
Sbjct: 225 KTVNTKRVIQYFAIVAALGDGPGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRND 284
Query: 241 NSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIE 300
NSSRFGKFIRIHFG +GKLASADI++YLLEKSRV FQL ERSYH++YQILS +KPEL +
Sbjct: 285 NSSRFGKFIRIHFGPSGKLASADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQD 344
Query: 301 LLLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHY 360
+LL++ NPYDY F SQG I V +++D EEL+ATD A+DILGF+ +EK YK+ GA++H+
Sbjct: 345 MLLLSMNPYDYHFCSQGVITVDNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHF 404
Query: 361 GNMKFKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQ 420
GNMKFKQKQREEQAE DGTE ADK AYLMG++S DLLK L PRV+VGNEYVTKGQ+V+Q
Sbjct: 405 GNMKFKQKQREEQAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQ 464
Query: 421 VHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCIN 480
V AV AL+K+ Y++LF W+V+RINQ LDTKLPRQ FIGVLDIAGFEIFE+NS EQLCIN
Sbjct: 465 VVFAVGALAKATYDRLFRWLVSRINQTLDTKLPRQFFIGVLDIAGFEIFEFNSFEQLCIN 524
Query: 481 FTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECM 540
FTNEKLQQFFN HMFVLEQEEYK+EGI+W FIDFG+DL CI+LIEKP+GI SILEEECM
Sbjct: 525 FTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPLGILSILEEECM 584
Query: 541 FPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRA-EAHFSLIHYAGTVDYSVSGWLEKNK 599
FPKA+D SF+ KLYD H GKS NFQ+P+ K R +AHF ++HYAG V YS+ GWLEKNK
Sbjct: 585 FPKASDASFRAKLYDNHAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNK 644
Query: 600 DPLNETVVGLYQKSSNRLLAHLYATFA----TADADSGKKKVAKKKGSSFQTVSALFREN 655
DPLNETVV ++QKS NRLLA LY +A T SG K+ +KK +SFQTVS L +EN
Sbjct: 645 DPLNETVVPIFQKSQNRLLATLYENYAGSCSTEPPKSGVKE-KRKKAASFQTVSQLHKEN 703
Query: 656 LNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRIL 715
LNKLM+NLR T PHFVRCI+PNE KTPG M+ LVLHQLRCNGVLEGIRICR+GFPNR+L
Sbjct: 704 LNKLMTNLRATQPHFVRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLL 763
Query: 716 YGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLE 775
Y DF+QRYR+LN SAIP+ F+DS+KA EKLL S+D+DHTQY+FGHTKVFFKAGLLG LE
Sbjct: 764 YTDFRQRYRILNPSAIPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLE 823
Query: 776 EMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFF 835
E+RD RLAK++T QA RG LMR+E+Q+++ R+++F IQ+NIR+F VK+W WMKLFF
Sbjct: 824 ELRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKLFF 883
Query: 836 KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAE 895
K+KPLL+SA+ E+E+A ++ E + + LA +EAKR+ELEE V++ QEKNDL LQ+QAE
Sbjct: 884 KMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAE 943
Query: 896 SENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 955
+NL DAEERC LIK+K QLE K+KE++ER EDEEE+NA+L A++RKLEDEC+ELKKDI
Sbjct: 944 QDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDI 1003
Query: 956 DDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEE 1015
DDL+LTLAK EKEK ATENKVKNLTEE++ LDE++A+LT+EKKALQEAHQQAL DLQAEE
Sbjct: 1004 DDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEE 1063
Query: 1016 DKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQ 1075
D+V++L K K +LEQQVEDLE SLEQEKKLR+D ER KRKLEGDLKL QES+ D DKQ
Sbjct: 1064 DRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQ 1123
Query: 1076 QLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEK 1135
QL+E+LKKKD E QL +VEDEQ LG Q QKKIKELQAR EELEEE+EAERA RA+ EK
Sbjct: 1124 QLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEK 1183
Query: 1136 QRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRK 1195
QR++ ARELEELSERLEEAGG ++ Q E +KREAE +LRR+LEEA L+HEA VAALR+
Sbjct: 1184 QRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRR 1243
Query: 1196 KHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLED 1255
K A+ AELGEQ+D+LQRV+QKLEKEKSE ++E+DDL++++E+++++KA+ EK+CRT ED
Sbjct: 1244 KQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYED 1303
Query: 1256 QLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEE 1315
QLSEA+ K EE+QR L++ +TQ+ RLQTE+GELSR LEEKE ++SQLSR K Q EE
Sbjct: 1304 QLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEE 1363
Query: 1316 LKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTK 1375
L+RQLEEE+KAK+ALAHA+Q+ RHDCDLLREQ+EEE E +AELQR LSKAN+EVAQWR+K
Sbjct: 1364 LRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSK 1423
Query: 1376 YETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVER 1435
YE DAIQRTEELEEAKKKLA RLQ++EE VEA NAKC+SLEK K RLQ E ED+ +++ER
Sbjct: 1424 YEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELER 1483
Query: 1436 ANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQ 1495
A S AAALDKKQR+ ++ L E + + EE Q ELEA+ +ESR L TELF+L++ +EEAL+
Sbjct: 1484 ATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEA 1543
Query: 1496 LETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHE 1555
LET+KRENKNL++EI+DLT+Q++ +GK+I ELEK++K +E EK++IQ ALEEAE ALE E
Sbjct: 1544 LETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELE 1603
Query: 1556 EAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRL 1615
E K LRIQLEL+QVK+E+DRK+AEKDEE L+RN+QR VE++Q++LDAE R+RNEA+RL
Sbjct: 1604 ETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRL 1663
Query: 1616 KKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIV 1675
KKKMEGDLN++E+QL HA RQA E R +Q QLK+ Q D+ R +L EQ +
Sbjct: 1664 KKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQAL 1723
Query: 1676 ERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDL 1735
ERRA+LL AE+EELRA LEQ ER+R+LAEQELL++ ER+ LLH+QNT L++ KKKLE DL
Sbjct: 1724 ERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADL 1783
Query: 1736 MQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1795
QL EVE+A+++ R AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK LEQTV++LQ
Sbjct: 1784 AQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQ 1843
Query: 1796 HRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQS 1855
RL+EAEQ AL+GGKKQ+QKLE ++RELE EL+ EQKK+ E++KG+RK+ERRVKEL YQ+
Sbjct: 1844 ARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQA 1903
Query: 1856 EEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAE 1915
EEDRKN+ R+QDLVDKLQ KVKSYKRQ EEA++QAN +L K+RKAQHEL++AEERAD+AE
Sbjct: 1904 EEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAE 1963
Query: 1916 SQVNKLRAKTRD 1927
+Q NKLRA+TRD
Sbjct: 1964 TQANKLRARTRD 1975
Score = 144 bits (363), Expect = 8e-34
Identities = 148/697 (21%), Positives = 291/697 (41%), Gaps = 44/697 (6%)
Query: 1244 ANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLS 1303
A L R L L+ A K +E++ + +T +K+ L + L + E L
Sbjct: 899 AALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLI 958
Query: 1304 RSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALS 1363
+SK + +EL +LE+E + LA + +C L++ ++ L+ L+
Sbjct: 959 KSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDD-------LKLTLA 1011
Query: 1364 KANSE--VAQWRTKYETDAIQRTEE----LEEAKKKLAQRLQDSEEQVEAVNAKCASLEK 1417
KA E + + K T+ + +E L + KK L + Q + ++A + ++L K
Sbjct: 1012 KAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTK 1071
Query: 1418 TKQRLQGEVEDLMVDVERANSLAAALDKKQRNFD---KVLAEWKTKCEESQAELEASLKE 1474
K RL+ +VEDL +E+ L ++ +R + K+ E + + +LE LK+
Sbjct: 1072 AKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKK 1131
Query: 1475 SRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQI 1534
S EL +L E+ ++++ K L+ +L E++ +EK R +
Sbjct: 1132 KDS---ELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEA 1188
Query: 1535 ELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRT 1594
E ++ LEEA A + + + EL +++ E++ + + L+R
Sbjct: 1189 ARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEG 1248
Query: 1595 VETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDT 1654
+ +D+ R R + + K ++ +++++ + R A K R+ + QL +
Sbjct: 1249 AAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEA 1308
Query: 1655 QLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERV 1714
++ +++ R D Q ++ + L +EE + Q R + LA Q L + ++
Sbjct: 1309 KIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQL 1368
Query: 1715 QLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQ 1774
+ ++L H + L D L+ + E+ + + KA + A K E
Sbjct: 1369 EEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRS--KYEA 1426
Query: 1775 DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKK--QIQKLETRIRELEFELEGEQK 1832
D E LE+ K L RL EAE+ K ++K + R++ ++ E +
Sbjct: 1427 DAIQRTEE----LEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELE 1482
Query: 1833 KNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANA 1892
+ T + L K +R ++ EE R+ +Q R+ E A ++
Sbjct: 1483 RATSAAAALDKKQRHLERAL---EERRRQEEEMQ--------------RELEAAQRESRG 1525
Query: 1893 HLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFT 1929
T+ + +H EEA E + + + L+ + D T
Sbjct: 1526 LGTELFRLRHGHEEALEALETLKRENKNLQEEISDLT 1562
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 2300 bits (5960), Expect = 0.0
Identities = 1156/1926 (60%), Positives = 1511/1926 (78%), Gaps = 11/1926 (0%)
Query: 6 EMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSKEEYAKGKIKSSQD-GKVTVET 64
++ G AA FLR+SE E + Q D K C++ D + Y + ++K S+D G V VET
Sbjct: 22 DLSDLGEAAAFLRRSEAELLLLQATALDGKKKCWIPDGENAYIEAEVKGSEDDGTVIVET 81
Query: 65 EDNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCV 124
D +L +K + + MNPP+F+ IEDMAMLTHLNE +VL+ LK RY WMIYTYSGLFCV
Sbjct: 82 ADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCV 141
Query: 125 TVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 184
T+NPYKWLPVY EV+ Y+GK+R EAPPHIF++++NA+Q ML +RENQSIL TGESGAG
Sbjct: 142 TINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAG 201
Query: 185 KTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSR 244
KTVN+K +IQYFATIAA + KK+ G LEDQI+ AN +LEAFGNAKT+RNDNSSR
Sbjct: 202 KTVNSKHIIQYFATIAAMIESRKKQ-----GALEDQIMQANTILEAFGNAKTLRNDNSSR 256
Query: 245 FGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIELLLI 304
FGKFIR+HFG G L+S DI+ YLLEKSRV FQ ER+YHIFYQILS +K EL +LLL+
Sbjct: 257 FGKFIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSGQK-ELHDLLLV 315
Query: 305 TTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMK 364
+ NP D+ F S G + V S+DDAEELLAT+ A+DILGF P+EK G YKLTGA+MH+GNMK
Sbjct: 316 SANPSDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMK 375
Query: 365 FKQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHA 424
FKQK REEQ E DGTE ADK A+LMG+NSS+L+K L PR+KVGNEYVT+GQT++QV A
Sbjct: 376 FKQKPREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCA 435
Query: 425 VNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNE 484
V ALSKS+YE++F W+V RIN+ LD KL RQ FIG+LDI GFEI EYNSLEQLCINFTNE
Sbjct: 436 VGALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEILEYNSLEQLCINFTNE 495
Query: 485 KLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKA 544
KLQQFFN HMFVLEQEEYKKE IEW I FG+DL ACI+LIEKPMGI SILEEECMFPKA
Sbjct: 496 KLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILSILEEECMFPKA 555
Query: 545 TDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNE 604
TD +FK KL+D H GKS + QKPK K + EAHF L+HYAG V Y++SGWLEKNKD LNE
Sbjct: 556 TDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNE 615
Query: 605 TVVGLYQKSSNRLLAHLYATFATADA--DSGKKKVAKKKGSSFQTVSALFRENLNKLMSN 662
TVV ++QKSSNRLLA L+ + + D+ G+KK +KKG+SFQTV++L +ENLNKLM+N
Sbjct: 616 TVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKK--RKKGASFQTVASLHKENLNKLMTN 673
Query: 663 LRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQR 722
L++T PHFVRCI PN K PG ++ LVL QLRCNGVLEG RICR+GFPNR+ Y DFKQR
Sbjct: 674 LKSTAPHFVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQR 733
Query: 723 YRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRL 782
Y +LN P+ +F+ S+KA E+LL S++IDHTQY+FG TKVFFKAG LG LE +RD+RL
Sbjct: 734 YCILNPRTFPKSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERL 793
Query: 783 AKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLK 842
+K+ T QA +G LMR++FQK+++ R+++ IQ+NIR+FM VK+WPWM+LFFKIKPL+K
Sbjct: 794 SKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVK 853
Query: 843 SAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDA 902
S+E +E+A +KEE + + L KSE +R+EL+ K V+L QEKNDL LQ+QAE E L +
Sbjct: 854 SSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANV 913
Query: 903 EERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTL 962
EE+C+ LIK+K QLEA++KE++ER E+EEEIN+ELTA+ RKLEDEC ELKK+IDDLE L
Sbjct: 914 EEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETML 973
Query: 963 AKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLN 1022
K EKEK TE+KVKNLTEE+ L+E I+KL R K +QEAHQQ LDDL EE+K++SL+
Sbjct: 974 VKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLS 1033
Query: 1023 KTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLK 1082
K KLEQQV++LE +LEQE+K R++ ER KLEG+LKL +ES+ +LE+ ++ L E L+
Sbjct: 1034 KANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELR 1093
Query: 1083 KKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYAR 1142
KK+ E Q+ SKVE+E+ L Q QK +KELQ +I++L+E++EAER TRAK E++R+D +
Sbjct: 1094 KKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQ 1153
Query: 1143 ELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVA 1202
+L +L+ERLEE GG + Q+E+ KK+E +F KL RD+EEATL E A+L+K+HADS+A
Sbjct: 1154 DLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLA 1213
Query: 1203 ELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARG 1262
EL Q++NLQ+VKQKLEK+KS+ +LE+DDL + +E ++++KAN EK+C E++L EA
Sbjct: 1214 ELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATA 1273
Query: 1263 KNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEE 1322
K +++ + ++L QK++L +E+GE R+LEEKE++++QLSR K FT+Q E+L+ QLE+
Sbjct: 1274 KLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEK 1333
Query: 1323 ENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQ 1382
E K+++ALAHALQ ++ DCDLLREQYEEEQE KAEL R LSK N+E+ QWR KYE + IQ
Sbjct: 1334 ETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQ 1393
Query: 1383 RTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAA 1442
RTE+LE+AKK+LA RLQ++ E + NA+ ASLE+ + +LQ E+ D + D+ + S AA
Sbjct: 1394 RTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAAR 1453
Query: 1443 LDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRE 1502
LD+KQ K LA+WK K EESQA L+AS KE ++LSTEL KLKN YEE++ ET++RE
Sbjct: 1454 LDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRE 1513
Query: 1503 NKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRI 1562
NKNL++EI++LT Q+ E K + E+EK +K IE EK ++Q+ LEE E ALE E+KIL
Sbjct: 1514 NKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHF 1573
Query: 1563 QLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGD 1622
QLEL + K+E++RK++EKDEEIE +R Q T++++QS+LD+E +SR E RLKKKME D
Sbjct: 1574 QLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEED 1633
Query: 1623 LNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLL 1682
LNE+E+QLS ANRQ +E K L +Q Q+KD Q+ LDD+ + DLKEQ+A+ ERR +LL
Sbjct: 1634 LNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLL 1693
Query: 1683 QAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEV 1742
Q+E+E+LR+ EQTER R+L+E+ELL++ ER+ L +TQNTSL+ KKKLE D+ ++Q E
Sbjct: 1694 QSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEA 1753
Query: 1743 EDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAE 1802
E+ ++ +NAEEKAKKA +AA ++EELKK+QDT AHLER ++N+EQT+ DLQ RL EAE
Sbjct: 1754 EEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAE 1813
Query: 1803 QLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNV 1862
Q+AL G +KQIQKLE+R+RELE ELEGE +++ E+ +G R+ ER +KELTYQ+EED+KN+
Sbjct: 1814 QMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNL 1873
Query: 1863 LRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLR 1922
R+Q +DKLQ+KV++YK+Q E A+ QAN +L+K++K QHEL E +ERA++AESQVNKL+
Sbjct: 1874 SRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLK 1933
Query: 1923 AKTRDF 1928
K R+F
Sbjct: 1934 IKAREF 1939
Score = 99.0 bits (245), Expect = 4e-20
Identities = 115/492 (23%), Positives = 210/492 (42%), Gaps = 64/492 (13%)
Query: 1473 KESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRK 1532
+E L E +L+ A E++ Q E +K + +L QE DL Q+ +T+ +E+ +
Sbjct: 859 EEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCE 918
Query: 1533 QIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQ 1592
+ K ++ ++E +E EE I ELT +++ + E +EI+ L
Sbjct: 919 WLIKSKIQLEARVKELSERVEEEE----EINSELTARGRKLEDECFELKKEIDDL----- 969
Query: 1593 RTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLK 1652
ETM + E R+ ++ + LNE +S NR A K ++ Q
Sbjct: 970 ---ETMLVKSEKEKRTTEHKVKNLTEEVEFLNE---DISKLNRAA----KVVQEAHQQTL 1019
Query: 1653 DTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQEL--LDS 1710
D LH+++ E+L+ + + L+ +V+EL LEQ +AR E+EL L+
Sbjct: 1020 D-DLHMEE---------EKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEG 1069
Query: 1711 N-----ERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAM 1765
N E ++ L + L +K E +L Q+ S+VE+ ++ K+ T
Sbjct: 1070 NLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKD 1129
Query: 1766 MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLAL------KGGKKQIQKLET- 1818
+ E+L+ E+ T A +ER + +L Q + DL RL+E +L K + + QKL
Sbjct: 1130 LKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRD 1189
Query: 1819 ---------------------RIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEE 1857
+ ELE ++E Q+ + K + V +L + E+
Sbjct: 1190 MEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQ 1249
Query: 1858 DRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQ 1917
+ + L + ++ + ++ + AN + K E E R + E+
Sbjct: 1250 MTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEAL 1309
Query: 1918 VNKLRAKTRDFT 1929
+N+L + +FT
Sbjct: 1310 INQLSREKSNFT 1321
Score = 94.4 bits (233), Expect = 1e-18
Identities = 78/320 (24%), Positives = 151/320 (47%), Gaps = 28/320 (8%)
Query: 845 ETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQV----------QA 894
E E +++ + + L + + + K+L+ +L Q +DL+ QV Q+
Sbjct: 1636 EMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQS 1695
Query: 895 ESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKD 954
E E+L +E+ + + + E ++ E TER N L ++K+KLE + + ++K+
Sbjct: 1696 ELEDLRSLQEQTE---RGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKE 1752
Query: 955 IDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQ-- 1012
+++ E++ + NL+EEL +TIA L R ++ ++ Q + DLQ
Sbjct: 1753 AEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENME----QTITDLQKR 1808
Query: 1013 ---AEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILD 1069
AE+ + K KLE +V +LE LE E + + +R R+LE +K E
Sbjct: 1809 LAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIK---ELTYQ 1865
Query: 1070 LENDKQQLDE---RLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAE 1126
E DK+ L ++ K + + +VE +T Q+ K K+ Q + E++E E
Sbjct: 1866 AEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVA 1925
Query: 1127 RATRAKTEKQRSDYARELEE 1146
+ K + + ++ ++++E
Sbjct: 1926 ESQVNKLKIKAREFGKKVQE 1945
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 1424 bits (3686), Expect = 0.0
Identities = 780/1908 (40%), Positives = 1182/1908 (61%), Gaps = 25/1908 (1%)
Query: 34 AKTYCFVVDSKEEYAKGKIKSSQDGKVTVE-TEDNRTLVVKPEDVYAMNPPKFDRIEDMA 92
AK +V K+ + IK + +V VE E+ + + V +D+ MNPPKF ++EDMA
Sbjct: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
Query: 93 MLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAP 152
LT LNE +VL+NL++RY S +IYTYSGLFCV VNPYK LP+Y+ ++V+ Y+GKKR E P
Sbjct: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSK 212
PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A++ KKD+
Sbjct: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHK--GKKDTS 209
Query: 213 MKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKS 272
+ G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLEKS
Sbjct: 210 ITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKS 269
Query: 273 RVTFQLKAERSYHIFYQILSNKKPEL-IELLLITTNPYDYPFISQGEILVASIDDAEELL 331
R Q + ER++HIFY +++ K ++ +LLL N +Y F+S G + + + D E
Sbjct: 270 RAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDDEMFQ 327
Query: 332 ATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLMGL 391
T A+ I+GF+ EE+ + K+ +V+ GN+ FK+++ +QA A K +LMG+
Sbjct: 328 ETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGI 387
Query: 392 NSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLDTK 451
N +D +++ PR+KVG + V K QT +Q AV AL+K+ YE+LF W++TR+N+ LD K
Sbjct: 388 NVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALD-K 446
Query: 452 LPRQ--HFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 509
RQ F+G+LDIAGFEIFE NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 447 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
Query: 510 TFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQK 566
FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G FQK
Sbjct: 507 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565
Query: 567 PKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYATF- 625
PK +K + E FS+IHYAG VDY+ S WL KN DPLN+ V L SS++ +A L+
Sbjct: 566 PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623
Query: 626 -------ATADADSGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNE 678
+S +K K F+TV L++E L KLM+ LR T P+FVRCIIPN
Sbjct: 624 RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
Query: 679 TKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFID 738
K G ++ LVL QLRCNGVLEGIRICR+GFPNRI++ +F+QRY +L A+AIP+G F+D
Sbjct: 684 EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742
Query: 739 SKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLM 798
K+AC ++ ++++D Y+ G +K+FF+ G+L LEE RD ++ +I QA+CRG+L
Sbjct: 743 GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802
Query: 799 RVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 858
R F K Q+ ++ IQ N +++ +++W W +LF K+KPLL+ E+EM ++E Q
Sbjct: 803 RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862
Query: 859 KTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEA 918
KTK+ K+E + KELE+K L +EKN LQ Q+QAE+E +AEE +L K +LE
Sbjct: 863 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
Query: 919 KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 978
+ E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK E K+K
Sbjct: 923 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
Query: 979 LTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESS 1038
L +E+ +D+ KL++E+K L+E +L EE+K +L K K+K E + +LE
Sbjct: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
Query: 1039 LEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDE 1098
L++E+K R +LE+ KRKLEGD E I DL+ +L +L KK+ E ++++DE
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
Query: 1099 QTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVT 1158
KKI+EL+ I +L+E++++ERA R K EKQ+ D ELE L LE+ T
Sbjct: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
Query: 1159 STQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKL 1218
+TQ EL KRE E L++ L+E T HEA V +R+KHA +V EL EQ++ +R K L
Sbjct: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
Query: 1219 EKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQK 1278
+K K + E DL+ + + ++K +E + LE Q+ E + K + +R+ +EL +
Sbjct: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
Query: 1279 SRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSR 1338
+LQ E ++ L E E +L++ + + Q ++ + L+EE + K ++ L+
Sbjct: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
Query: 1339 HDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1398
+ + L++Q +EE E K L+R +S N +++ + K + D E LEE KK+ + +
Sbjct: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401
Query: 1399 QDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWK 1458
++ +Q E A LEKTK RLQ E++DL+VD++ L + L+KKQR FD++LAE K
Sbjct: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
Query: 1459 TKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIA 1518
+ E + + E+R T+ L A EEAL+ E ++R NK L+ E+ DL
Sbjct: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521
Query: 1519 ENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIA 1578
+ GK +HELEKS++ +E + +++ LEE E L+ E LR+++ + +K + +R +
Sbjct: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581
Query: 1579 EKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAA 1638
+DE+ E+ +R QR + ++ L+ E + R A KKK+EGDL ++E+Q A +
Sbjct: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641
Query: 1639 ETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTER 1698
E +K LR +Q Q+KD Q L+DA ++++ E++A L+A++ +L+ L ER
Sbjct: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701
Query: 1699 ARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKK 1758
ARK A+ E + E + + +L K++LE + QL+ E+E+ + ++ +K
Sbjct: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761
Query: 1759 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLET 1818
A A ++ EL E+ T+ E ++ LE+ K+L+ +L E E K I LE
Sbjct: 1762 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821
Query: 1819 RIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKS 1878
+I +LE ++E E ++ + K L++ ++++KE+ Q E++RK + ++ +K +VK
Sbjct: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881
Query: 1879 YKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTR 1926
KRQ EEA+E++ RK Q EL+EA E + +VN L++K R
Sbjct: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 211 bits (537), Expect = 6e-54
Identities = 214/990 (21%), Positives = 431/990 (43%), Gaps = 152/990 (15%)
Query: 845 ETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESE------- 897
+ E+++ + QK + E +EAK K+LE++++ + + N L + + E
Sbjct: 954 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1013
Query: 898 NLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 957
NL + EE+ L K K + E+ I E+ R + EE+ EL KRKLE + S+ + I D
Sbjct: 1014 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1073
Query: 958 LE-------LTLAKVEKE--------------KHATENKVKNLTEELSGLDETIAK---- 992
L+ + LAK E+E K+ K++ L +S L E +
Sbjct: 1074 LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1133
Query: 993 ----------LTREKKALQEAHQQALD------DLQAE-EDKVNSLNKT----------- 1024
L E +AL+ + LD +L+A+ E +V L K
Sbjct: 1134 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1193
Query: 1025 ----KSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDER 1080
+ K Q VE+L LEQ K+ + +L++NK+ LE + + L KQ+++ +
Sbjct: 1194 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK 1253
Query: 1081 LKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY 1140
KK + + +LQSK D + + K+ +LQ +E + + K K +
Sbjct: 1254 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1313
Query: 1141 ARELEELSERLEEAG----GVTSTQIELNKKREA------EFLKLRRDLEE--ATLQHE- 1187
+ +L++ E L+E V++ +L ++R + E ++ +++LE +TL +
Sbjct: 1314 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1373
Query: 1188 -----------AMVAAL---RKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLS 1233
+ V AL +K+ + L +Q + KLEK K+ + E+DDL
Sbjct: 1374 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1433
Query: 1234 SSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLE 1293
+++ + +NLEK R + L+E + + + + +T+A L+R LE
Sbjct: 1434 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1493
Query: 1294 EKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQE 1353
E +L R+ + + E+L ++ K + L + ++ + ++ Q EE ++
Sbjct: 1494 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1553
Query: 1354 GKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCA 1413
+ A + + + ++E D R E+ EE +++L ++L + E ++E + A
Sbjct: 1554 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 1613
Query: 1414 SLEKTKQRLQGEVEDLMVDV-------ERANSLAAALDKKQRNFDKVLAEWKTKCEESQA 1466
K++L+G+++DL + E A L + ++F + L + + +E A
Sbjct: 1614 LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA 1673
Query: 1467 ELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHE 1526
+ + K+++SL +L +L+ + L +R K + E +L E++A + +
Sbjct: 1674 TAKENEKKAKSLEADLMQLQ-------EDLAAAERARKQADLEKEELAEELASSLSGRNA 1726
Query: 1527 LEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEI--DRKIAEKDE-- 1582
L+ ++++E A ++ LEE + +E ++ + + Q+ +E+ +R A+K+E
Sbjct: 1727 LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESA 1786
Query: 1583 --EIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAET 1640
++E+ + + + M+ A+ ++ +S A+ K + ++E Q+ R+
Sbjct: 1787 RQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAK------IAQLEEQVEQEAREKQAA 1840
Query: 1641 LKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEE------------ 1688
K L+ +LK+ L ++D + E KEQ R L+ ++EE
Sbjct: 1841 TKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANR 1900
Query: 1689 -----------------------LRATLEQ 1695
L++ L +
Sbjct: 1901 RKLQRELDEATESNEAMGREVNALKSKLRR 1930
Score = 139 bits (350), Expect = 3e-32
Identities = 138/564 (24%), Positives = 259/564 (45%), Gaps = 52/564 (9%)
Query: 838 KPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVT----LVQEKNDLQLQVQ 893
K L A T + + K+ FQK + L + ++ +KL L QE +DL + +
Sbjct: 1378 KKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1437
Query: 894 AESE---NLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEE------------------E 932
+ + NL + + DQL+ + + +K + +RAE E E
Sbjct: 1438 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALE 1497
Query: 933 INAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAK 992
EL + L+ E +L DD+ + ++EK K A E +++ + +L L++ + +
Sbjct: 1498 AKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL-Q 1556
Query: 993 LTREKKALQEAHQQALD-----DLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRV 1047
T + K E + QAL DLQA +++ + + +L++Q+ + E+ LE E+K R
Sbjct: 1557 ATEDAKLRLEVNMQALKGQFERDLQARDEQNE---EKRRQLQRQLHEYETELEDERKQRA 1613
Query: 1048 DLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQK 1107
K+KLEGDLK + +++ ++L+K + Q ++ED + +
Sbjct: 1614 LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA 1673
Query: 1108 KIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKK 1167
KE + + + LE ++ + A E+ R E EEL+E L + + + ++
Sbjct: 1674 TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR 1733
Query: 1168 REAEFLKLRRDLEEATLQHEAMVAALRK--KHADSVA-ELGEQIDNLQR---VKQKLEKE 1221
EA +L +LEE EAM +RK + A+ ++ EL + Q+ +Q+LE++
Sbjct: 1734 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1793
Query: 1222 KSEFKLEIDDLSSSMESVSKSK-ANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSR 1280
E + ++ ++ +++S KS A LE LE+Q+ + + + +SL QK +
Sbjct: 1794 NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK----QKDK 1849
Query: 1281 LQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQL---EEENKAKNALAHALQSS 1337
+ E+ Q+E++ + Q + + ++LKRQL EEE++ NA LQ
Sbjct: 1850 ---KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1906
Query: 1338 RHDCDLLREQYEEEQEG-KAELQR 1360
+ E E K++L+R
Sbjct: 1907 LDEATESNEAMGREVNALKSKLRR 1930
Score = 131 bits (330), Expect = 6e-30
Identities = 124/538 (23%), Positives = 251/538 (46%), Gaps = 51/538 (9%)
Query: 1404 QVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEE 1463
Q E + AK L+KTK+R Q + E+ + ++E+ +S ++K +++ AE + E
Sbjct: 850 QEEEMQAKEDELQKTKERQQ-KAENELKELEQKHSQLT--EEKNLLQEQLQAETELYAEA 906
Query: 1464 SQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKT 1523
+ + + K+ + L L +++ EE D+ + ++ E K + Q++ DL EQ+ E
Sbjct: 907 EEMRVRLAAKK-QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE--- 962
Query: 1524 IHELEKSRKQIELEKADIQLALEEAE---AALEHEEAKILRIQLELTQVKSEIDRKIAEK 1580
E +R++++LEK + +++ E ++ + K+ + + L + S++ +AE+
Sbjct: 963 ----EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1018
Query: 1581 DEE---IEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQA 1637
+E+ + +LK ++ + ++ L E +SR E +LK+K+EGD ++ Q++ Q
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078
Query: 1638 AETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTE 1697
AE L + +L+ LDD + + + +++ +E + LQ +++ RA
Sbjct: 1079 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA------ 1132
Query: 1698 RARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAK 1757
AR AE++ K+ L +L L++E+ED +E
Sbjct: 1133 -ARNKAEKQ---------------------KRDLGEELEALKTELEDTLDSTATQQELRA 1170
Query: 1758 KAITDAAMMAEELKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1816
K + ++ + L +E + A ++ M++ Q V++L +L++ ++ K + Q L
Sbjct: 1171 KREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK-QTL 1229
Query: 1817 ETRIRELEFELE--GEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQV 1874
E +L EL G+ K+ E K +K E +V+EL + + + L D V KLQ
Sbjct: 1230 EKENADLAGELRVLGQAKQEVEHKK--KKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1287
Query: 1875 KVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSSR 1932
+V+S EA+ +A +L++ +E Q + K R R
Sbjct: 1288 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1345
Score = 79.0 bits (193), Expect = 4e-14
Identities = 75/314 (23%), Positives = 138/314 (43%), Gaps = 21/314 (6%)
Query: 1616 KKKMEGDLNEIEIQLSHANRQAAET-LKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAI 1674
+++ E E E+Q + +Q AE LK L QL + + L + L+ + +L
Sbjct: 849 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETEL------ 902
Query: 1675 VERRANLLQAEVEELRATLEQTERARKLAEQELLDSNE-RVQLLHTQNTSLIHTKKKLET 1733
AE EE+R L A+K +E+L E R++ + L +KK+
Sbjct: 903 --------YAEAEEMRVRLA----AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQ 950
Query: 1734 DLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKD 1793
++ L+ ++E+ + + + A + +E+ D + L + +K LE+ + D
Sbjct: 951 QMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1010
Query: 1794 LQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTY 1853
L L E E+ A K K K E+ I ELE L+ E+K E K RK E +
Sbjct: 1011 LTTNLAEEEEKA-KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1069
Query: 1854 QSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADI 1913
Q + + + L+ + K + ++++ + ++ Q N L K R+ + + + +E D
Sbjct: 1070 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDS 1129
Query: 1914 AESQVNKLRAKTRD 1927
+ NK + RD
Sbjct: 1130 ERAARNKAEKQKRD 1143
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 1424 bits (3686), Expect = 0.0
Identities = 780/1908 (40%), Positives = 1182/1908 (61%), Gaps = 25/1908 (1%)
Query: 34 AKTYCFVVDSKEEYAKGKIKSSQDGKVTVE-TEDNRTLVVKPEDVYAMNPPKFDRIEDMA 92
AK +V K+ + IK + +V VE E+ + + V +D+ MNPPKF ++EDMA
Sbjct: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
Query: 93 MLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAP 152
LT LNE +VL+NL++RY S +IYTYSGLFCV VNPYK LP+Y+ ++V+ Y+GKKR E P
Sbjct: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSK 212
PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A++ KKD+
Sbjct: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHK--GKKDTS 209
Query: 213 MKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKS 272
+ G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLEKS
Sbjct: 210 ITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKS 269
Query: 273 RVTFQLKAERSYHIFYQILSNKKPEL-IELLLITTNPYDYPFISQGEILVASIDDAEELL 331
R Q + ER++HIFY +++ K ++ +LLL N +Y F+S G + + + D E
Sbjct: 270 RAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDDEMFQ 327
Query: 332 ATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLMGL 391
T A+ I+GF+ EE+ + K+ +V+ GN+ FK+++ +QA A K +LMG+
Sbjct: 328 ETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGI 387
Query: 392 NSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLDTK 451
N +D +++ PR+KVG + V K QT +Q AV AL+K+ YE+LF W++TR+N+ LD K
Sbjct: 388 NVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALD-K 446
Query: 452 LPRQ--HFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 509
RQ F+G+LDIAGFEIFE NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 447 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
Query: 510 TFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQK 566
FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G FQK
Sbjct: 507 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565
Query: 567 PKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYATF- 625
PK +K + E FS+IHYAG VDY+ S WL KN DPLN+ V L SS++ +A L+
Sbjct: 566 PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623
Query: 626 -------ATADADSGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNE 678
+S +K K F+TV L++E L KLM+ LR T P+FVRCIIPN
Sbjct: 624 RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
Query: 679 TKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFID 738
K G ++ LVL QLRCNGVLEGIRICR+GFPNRI++ +F+QRY +L A+AIP+G F+D
Sbjct: 684 EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742
Query: 739 SKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLM 798
K+AC ++ ++++D Y+ G +K+FF+ G+L LEE RD ++ +I QA+CRG+L
Sbjct: 743 GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802
Query: 799 RVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 858
R F K Q+ ++ IQ N +++ +++W W +LF K+KPLL+ E+EM ++E Q
Sbjct: 803 RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862
Query: 859 KTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEA 918
KTK+ K+E + KELE+K L +EKN LQ Q+QAE+E +AEE +L K +LE
Sbjct: 863 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
Query: 919 KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 978
+ E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK E K+K
Sbjct: 923 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
Query: 979 LTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESS 1038
L +E+ +D+ KL++E+K L+E +L EE+K +L K K+K E + +LE
Sbjct: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
Query: 1039 LEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDE 1098
L++E+K R +LE+ KRKLEGD E I DL+ +L +L KK+ E ++++DE
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
Query: 1099 QTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVT 1158
KKI+EL+ I +L+E++++ERA R K EKQ+ D ELE L LE+ T
Sbjct: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
Query: 1159 STQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKL 1218
+TQ EL KRE E L++ L+E T HEA V +R+KHA +V EL EQ++ +R K L
Sbjct: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
Query: 1219 EKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQK 1278
+K K + E DL+ + + ++K +E + LE Q+ E + K + +R+ +EL +
Sbjct: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
Query: 1279 SRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSR 1338
+LQ E ++ L E E +L++ + + Q ++ + L+EE + K ++ L+
Sbjct: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
Query: 1339 HDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1398
+ + L++Q +EE E K L+R +S N +++ + K + D E LEE KK+ + +
Sbjct: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401
Query: 1399 QDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWK 1458
++ +Q E A LEKTK RLQ E++DL+VD++ L + L+KKQR FD++LAE K
Sbjct: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
Query: 1459 TKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIA 1518
+ E + + E+R T+ L A EEAL+ E ++R NK L+ E+ DL
Sbjct: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521
Query: 1519 ENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIA 1578
+ GK +HELEKS++ +E + +++ LEE E L+ E LR+++ + +K + +R +
Sbjct: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581
Query: 1579 EKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAA 1638
+DE+ E+ +R QR + ++ L+ E + R A KKK+EGDL ++E+Q A +
Sbjct: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641
Query: 1639 ETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTER 1698
E +K LR +Q Q+KD Q L+DA ++++ E++A L+A++ +L+ L ER
Sbjct: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701
Query: 1699 ARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKK 1758
ARK A+ E + E + + +L K++LE + QL+ E+E+ + ++ +K
Sbjct: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761
Query: 1759 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLET 1818
A A ++ EL E+ T+ E ++ LE+ K+L+ +L E E K I LE
Sbjct: 1762 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821
Query: 1819 RIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKS 1878
+I +LE ++E E ++ + K L++ ++++KE+ Q E++RK + ++ +K +VK
Sbjct: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881
Query: 1879 YKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTR 1926
KRQ EEA+E++ RK Q EL+EA E + +VN L++K R
Sbjct: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 131 bits (330), Expect = 6e-30
Identities = 124/538 (23%), Positives = 251/538 (46%), Gaps = 51/538 (9%)
Query: 1404 QVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEE 1463
Q E + AK L+KTK+R Q + E+ + ++E+ +S ++K +++ AE + E
Sbjct: 850 QEEEMQAKEDELQKTKERQQ-KAENELKELEQKHSQLT--EEKNLLQEQLQAETELYAEA 906
Query: 1464 SQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKT 1523
+ + + K+ + L L +++ EE D+ + ++ E K + Q++ DL EQ+ E
Sbjct: 907 EEMRVRLAAKK-QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE--- 962
Query: 1524 IHELEKSRKQIELEKADIQLALEEAE---AALEHEEAKILRIQLELTQVKSEIDRKIAEK 1580
E +R++++LEK + +++ E ++ + K+ + + L + S++ +AE+
Sbjct: 963 ----EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1018
Query: 1581 DEE---IEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQA 1637
+E+ + +LK ++ + ++ L E +SR E +LK+K+EGD ++ Q++ Q
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078
Query: 1638 AETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTE 1697
AE L + +L+ LDD + + + +++ +E + LQ +++ RA
Sbjct: 1079 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA------ 1132
Query: 1698 RARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAK 1757
AR AE++ K+ L +L L++E+ED +E
Sbjct: 1133 -ARNKAEKQ---------------------KRDLGEELEALKTELEDTLDSTATQQELRA 1170
Query: 1758 KAITDAAMMAEELKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1816
K + ++ + L +E + A ++ M++ Q V++L +L++ ++ K + Q L
Sbjct: 1171 KREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK-QTL 1229
Query: 1817 ETRIRELEFELE--GEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQV 1874
E +L EL G+ K+ E K +K E +V+EL + + + L D V KLQ
Sbjct: 1230 EKENADLAGELRVLGQAKQEVEHKK--KKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1287
Query: 1875 KVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSSR 1932
+V+S EA+ +A +L++ +E Q + K R R
Sbjct: 1288 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1345
Score = 79.0 bits (193), Expect = 4e-14
Identities = 75/314 (23%), Positives = 138/314 (43%), Gaps = 21/314 (6%)
Query: 1616 KKKMEGDLNEIEIQLSHANRQAAET-LKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAI 1674
+++ E E E+Q + +Q AE LK L QL + + L + L+ + +L
Sbjct: 849 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETEL------ 902
Query: 1675 VERRANLLQAEVEELRATLEQTERARKLAEQELLDSNE-RVQLLHTQNTSLIHTKKKLET 1733
AE EE+R L A+K +E+L E R++ + L +KK+
Sbjct: 903 --------YAEAEEMRVRLA----AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQ 950
Query: 1734 DLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKD 1793
++ L+ ++E+ + + + A + +E+ D + L + +K LE+ + D
Sbjct: 951 QMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1010
Query: 1794 LQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTY 1853
L L E E+ A K K K E+ I ELE L+ E+K E K RK E +
Sbjct: 1011 LTTNLAEEEEKA-KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1069
Query: 1854 QSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADI 1913
Q + + + L+ + K + ++++ + ++ Q N L K R+ + + + +E D
Sbjct: 1070 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDS 1129
Query: 1914 AESQVNKLRAKTRD 1927
+ NK + RD
Sbjct: 1130 ERAARNKAEKQKRD 1143
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 1417 bits (3668), Expect = 0.0
Identities = 780/1915 (40%), Positives = 1182/1915 (61%), Gaps = 32/1915 (1%)
Query: 34 AKTYCFVVDSKEEYAKGKIKSSQDGKVTVE-TEDNRTLVVKPEDVYAMNPPKFDRIEDMA 92
AK +V K+ + IK + +V VE E+ + + V +D+ MNPPKF ++EDMA
Sbjct: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
Query: 93 MLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAP 152
LT LNE +VL+NL++RY S +IYTYSGLFCV VNPYK LP+Y+ ++V+ Y+GKKR E P
Sbjct: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSK 212
PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A++ KKD+
Sbjct: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHK--GKKDTS 209
Query: 213 MK-------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 265
+ G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IE
Sbjct: 210 ITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 269
Query: 266 TYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL-IELLLITTNPYDYPFISQGEILVASI 324
TYLLEKSR Q + ER++HIFY +++ K ++ +LLL N +Y F+S G + + +
Sbjct: 270 TYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAA 327
Query: 325 DDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADK 384
D E T A+ I+GF+ EE+ + K+ +V+ GN+ FK+++ +QA A K
Sbjct: 328 QDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQK 387
Query: 385 TAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRI 444
+LMG+N +D +++ PR+KVG + V K QT +Q AV AL+K+ YE+LF W++TR+
Sbjct: 388 VCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRV 447
Query: 445 NQQLDTKLPRQ--HFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 502
N+ LD K RQ F+G+LDIAGFEIFE NS EQLCIN+TNEKLQQ FNH MF+LEQEEY
Sbjct: 448 NKALD-KTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 506
Query: 503 KKEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLG 559
++EGIEW FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G
Sbjct: 507 QREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-G 565
Query: 560 KSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLA 619
FQKPK +K + E FS+IHYAG VDY+ S WL KN DPLN+ V L SS++ +A
Sbjct: 566 SHPKFQKPKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVA 623
Query: 620 HLYATF--------ATADADSGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFV 671
L+ +S +K K F+TV L++E L KLM+ LR T P+FV
Sbjct: 624 DLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFV 683
Query: 672 RCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAI 731
RCIIPN K G ++ LVL QLRCNGVLEGIRICR+GFPNRI++ +F+QRY +L A+AI
Sbjct: 684 RCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAI 743
Query: 732 PEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQA 791
P+G F+D K+AC ++ ++++D Y+ G +K+FF+ G+L LEE RD ++ +I QA
Sbjct: 744 PKG-FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQA 802
Query: 792 VCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMA 851
+CRG+L R F K Q+ ++ IQ N +++ +++W W +LF K+KPLL+ E+EM
Sbjct: 803 MCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQ 862
Query: 852 TMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIK 911
++E QKTK+ K+E + KELE+K L +EKN LQ Q+QAE+E +AEE +L
Sbjct: 863 AKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAA 922
Query: 912 AKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHA 971
K +LE + E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK
Sbjct: 923 KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVT 982
Query: 972 TENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQ 1031
E K+K L +E+ +D+ KL++E+K L+E +L EE+K +L K K+K E
Sbjct: 983 AEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESM 1042
Query: 1032 VEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQL 1091
+ +LE L++E+K R +LE+ KRKLEGD E I DL+ +L +L KK+ E
Sbjct: 1043 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 1102
Query: 1092 QSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERL 1151
++++DE KKI+EL+ I +L+E++++ERA R K EKQ+ D ELE L L
Sbjct: 1103 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 1162
Query: 1152 EEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNL 1211
E+ T+TQ EL KRE E L++ L+E T HEA V +R+KHA +V EL EQ++
Sbjct: 1163 EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQF 1222
Query: 1212 QRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSL 1271
+R K L+K K + E DL+ + + ++K +E + LE Q+ E + K + +R+
Sbjct: 1223 KRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERAR 1282
Query: 1272 SELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALA 1331
+EL + +LQ E ++ L E E +L++ + + Q ++ + L+EE + K ++
Sbjct: 1283 AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVS 1342
Query: 1332 HALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAK 1391
L+ + + L++Q +EE E K L+R +S N +++ + K + D E LEE K
Sbjct: 1343 TKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGK 1401
Query: 1392 KKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFD 1451
K+ + +++ +Q E A LEKTK RLQ E++DL+VD++ L + L+KKQR FD
Sbjct: 1402 KRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFD 1461
Query: 1452 KVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIA 1511
++LAE K + E + + E+R T+ L A EEAL+ E ++R NK L+ E+
Sbjct: 1462 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1521
Query: 1512 DLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKS 1571
DL + GK +HELEKS++ +E + +++ LEE E L+ E LR+++ + +K
Sbjct: 1522 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKG 1581
Query: 1572 EIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLS 1631
+ +R + +DE+ E+ +R QR + ++ L+ E + R A KKK+EGDL ++E+Q
Sbjct: 1582 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1641
Query: 1632 HANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRA 1691
A + E +K LR +Q Q+KD Q L+DA ++++ E++A L+A++ +L+
Sbjct: 1642 SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 1701
Query: 1692 TLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARN 1751
L ERARK A+ E + E + + +L K++LE + QL+ E+E+ +
Sbjct: 1702 DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA 1761
Query: 1752 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKK 1811
++ +KA A ++ EL E+ T+ E ++ LE+ K+L+ +L E E K
Sbjct: 1762 MSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKS 1821
Query: 1812 QIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDK 1871
I LE +I +LE ++E E ++ + K L++ ++++KE+ Q E++RK + ++ +K
Sbjct: 1822 TIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEK 1881
Query: 1872 LQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTR 1926
+VK KRQ EEA+E++ RK Q EL+EA E + +VN L++K R
Sbjct: 1882 GNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 211 bits (537), Expect = 6e-54
Identities = 214/990 (21%), Positives = 431/990 (43%), Gaps = 152/990 (15%)
Query: 845 ETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESE------- 897
+ E+++ + QK + E +EAK K+LE++++ + + N L + + E
Sbjct: 961 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1020
Query: 898 NLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDD 957
NL + EE+ L K K + E+ I E+ R + EE+ EL KRKLE + S+ + I D
Sbjct: 1021 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1080
Query: 958 LE-------LTLAKVEKE--------------KHATENKVKNLTEELSGLDETIAK---- 992
L+ + LAK E+E K+ K++ L +S L E +
Sbjct: 1081 LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1140
Query: 993 ----------LTREKKALQEAHQQALD------DLQAE-EDKVNSLNKT----------- 1024
L E +AL+ + LD +L+A+ E +V L K
Sbjct: 1141 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1200
Query: 1025 ----KSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDER 1080
+ K Q VE+L LEQ K+ + +L++NK+ LE + + L KQ+++ +
Sbjct: 1201 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK 1260
Query: 1081 LKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY 1140
KK + + +LQSK D + + K+ +LQ +E + + K K +
Sbjct: 1261 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1320
Query: 1141 ARELEELSERLEEAG----GVTSTQIELNKKREA------EFLKLRRDLEE--ATLQHE- 1187
+ +L++ E L+E V++ +L ++R + E ++ +++LE +TL +
Sbjct: 1321 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1380
Query: 1188 -----------AMVAAL---RKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLS 1233
+ V AL +K+ + L +Q + KLEK K+ + E+DDL
Sbjct: 1381 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1440
Query: 1234 SSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLE 1293
+++ + +NLEK R + L+E + + + + +T+A L+R LE
Sbjct: 1441 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1500
Query: 1294 EKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQE 1353
E +L R+ + + E+L ++ K + L + ++ + ++ Q EE ++
Sbjct: 1501 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1560
Query: 1354 GKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCA 1413
+ A + + + ++E D R E+ EE +++L ++L + E ++E + A
Sbjct: 1561 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 1620
Query: 1414 SLEKTKQRLQGEVEDLMVDV-------ERANSLAAALDKKQRNFDKVLAEWKTKCEESQA 1466
K++L+G+++DL + E A L + ++F + L + + +E A
Sbjct: 1621 LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA 1680
Query: 1467 ELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHE 1526
+ + K+++SL +L +L+ + L +R K + E +L E++A + +
Sbjct: 1681 TAKENEKKAKSLEADLMQLQ-------EDLAAAERARKQADLEKEELAEELASSLSGRNA 1733
Query: 1527 LEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEI--DRKIAEKDE-- 1582
L+ ++++E A ++ LEE + +E ++ + + Q+ +E+ +R A+K+E
Sbjct: 1734 LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESA 1793
Query: 1583 --EIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAET 1640
++E+ + + + M+ A+ ++ +S A+ K + ++E Q+ R+
Sbjct: 1794 RQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAK------IAQLEEQVEQEAREKQAA 1847
Query: 1641 LKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEE------------ 1688
K L+ +LK+ L ++D + E KEQ R L+ ++EE
Sbjct: 1848 TKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANR 1907
Query: 1689 -----------------------LRATLEQ 1695
L++ L +
Sbjct: 1908 RKLQRELDEATESNEAMGREVNALKSKLRR 1937
Score = 139 bits (350), Expect = 3e-32
Identities = 138/564 (24%), Positives = 259/564 (45%), Gaps = 52/564 (9%)
Query: 838 KPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVT----LVQEKNDLQLQVQ 893
K L A T + + K+ FQK + L + ++ +KL L QE +DL + +
Sbjct: 1385 KKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1444
Query: 894 AESE---NLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEE------------------E 932
+ + NL + + DQL+ + + +K + +RAE E E
Sbjct: 1445 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALE 1504
Query: 933 INAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAK 992
EL + L+ E +L DD+ + ++EK K A E +++ + +L L++ + +
Sbjct: 1505 AKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL-Q 1563
Query: 993 LTREKKALQEAHQQALD-----DLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRV 1047
T + K E + QAL DLQA +++ + + +L++Q+ + E+ LE E+K R
Sbjct: 1564 ATEDAKLRLEVNMQALKGQFERDLQARDEQNE---EKRRQLQRQLHEYETELEDERKQRA 1620
Query: 1048 DLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQK 1107
K+KLEGDLK + +++ ++L+K + Q ++ED + +
Sbjct: 1621 LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA 1680
Query: 1108 KIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKK 1167
KE + + + LE ++ + A E+ R E EEL+E L + + + ++
Sbjct: 1681 TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR 1740
Query: 1168 REAEFLKLRRDLEEATLQHEAMVAALRK--KHADSVA-ELGEQIDNLQR---VKQKLEKE 1221
EA +L +LEE EAM +RK + A+ ++ EL + Q+ +Q+LE++
Sbjct: 1741 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1800
Query: 1222 KSEFKLEIDDLSSSMESVSKSK-ANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSR 1280
E + ++ ++ +++S KS A LE LE+Q+ + + + +SL QK +
Sbjct: 1801 NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK----QKDK 1856
Query: 1281 LQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQL---EEENKAKNALAHALQSS 1337
+ E+ Q+E++ + Q + + ++LKRQL EEE++ NA LQ
Sbjct: 1857 ---KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1913
Query: 1338 RHDCDLLREQYEEEQEG-KAELQR 1360
+ E E K++L+R
Sbjct: 1914 LDEATESNEAMGREVNALKSKLRR 1937
Score = 131 bits (330), Expect = 6e-30
Identities = 124/538 (23%), Positives = 251/538 (46%), Gaps = 51/538 (9%)
Query: 1404 QVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEE 1463
Q E + AK L+KTK+R Q + E+ + ++E+ +S ++K +++ AE + E
Sbjct: 857 QEEEMQAKEDELQKTKERQQ-KAENELKELEQKHSQLT--EEKNLLQEQLQAETELYAEA 913
Query: 1464 SQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKT 1523
+ + + K+ + L L +++ EE D+ + ++ E K + Q++ DL EQ+ E
Sbjct: 914 EEMRVRLAAKK-QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE--- 969
Query: 1524 IHELEKSRKQIELEKADIQLALEEAE---AALEHEEAKILRIQLELTQVKSEIDRKIAEK 1580
E +R++++LEK + +++ E ++ + K+ + + L + S++ +AE+
Sbjct: 970 ----EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1025
Query: 1581 DEE---IEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQA 1637
+E+ + +LK ++ + ++ L E +SR E +LK+K+EGD ++ Q++ Q
Sbjct: 1026 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1085
Query: 1638 AETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTE 1697
AE L + +L+ LDD + + + +++ +E + LQ +++ RA
Sbjct: 1086 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA------ 1139
Query: 1698 RARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAK 1757
AR AE++ K+ L +L L++E+ED +E
Sbjct: 1140 -ARNKAEKQ---------------------KRDLGEELEALKTELEDTLDSTATQQELRA 1177
Query: 1758 KAITDAAMMAEELKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1816
K + ++ + L +E + A ++ M++ Q V++L +L++ ++ K + Q L
Sbjct: 1178 KREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK-QTL 1236
Query: 1817 ETRIRELEFELE--GEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQV 1874
E +L EL G+ K+ E K +K E +V+EL + + + L D V KLQ
Sbjct: 1237 EKENADLAGELRVLGQAKQEVEHKK--KKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1294
Query: 1875 KVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSSR 1932
+V+S EA+ +A +L++ +E Q + K R R
Sbjct: 1295 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1352
Score = 79.0 bits (193), Expect = 4e-14
Identities = 75/314 (23%), Positives = 138/314 (43%), Gaps = 21/314 (6%)
Query: 1616 KKKMEGDLNEIEIQLSHANRQAAET-LKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAI 1674
+++ E E E+Q + +Q AE LK L QL + + L + L+ + +L
Sbjct: 856 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETEL------ 909
Query: 1675 VERRANLLQAEVEELRATLEQTERARKLAEQELLDSNE-RVQLLHTQNTSLIHTKKKLET 1733
AE EE+R L A+K +E+L E R++ + L +KK+
Sbjct: 910 --------YAEAEEMRVRLA----AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQ 957
Query: 1734 DLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKD 1793
++ L+ ++E+ + + + A + +E+ D + L + +K LE+ + D
Sbjct: 958 QMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1017
Query: 1794 LQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTY 1853
L L E E+ A K K K E+ I ELE L+ E+K E K RK E +
Sbjct: 1018 LTTNLAEEEEKA-KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1076
Query: 1854 QSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADI 1913
Q + + + L+ + K + ++++ + ++ Q N L K R+ + + + +E D
Sbjct: 1077 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDS 1136
Query: 1914 AESQVNKLRAKTRD 1927
+ NK + RD
Sbjct: 1137 ERAARNKAEKQKRD 1150
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 1417 bits (3668), Expect = 0.0
Identities = 780/1915 (40%), Positives = 1182/1915 (61%), Gaps = 32/1915 (1%)
Query: 34 AKTYCFVVDSKEEYAKGKIKSSQDGKVTVE-TEDNRTLVVKPEDVYAMNPPKFDRIEDMA 92
AK +V K+ + IK + +V VE E+ + + V +D+ MNPPKF ++EDMA
Sbjct: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
Query: 93 MLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAP 152
LT LNE +VL+NL++RY S +IYTYSGLFCV VNPYK LP+Y+ ++V+ Y+GKKR E P
Sbjct: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSK 212
PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A++ KKD+
Sbjct: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHK--GKKDTS 209
Query: 213 MK-------GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 265
+ G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IE
Sbjct: 210 ITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 269
Query: 266 TYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL-IELLLITTNPYDYPFISQGEILVASI 324
TYLLEKSR Q + ER++HIFY +++ K ++ +LLL N +Y F+S G + + +
Sbjct: 270 TYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAA 327
Query: 325 DDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADK 384
D E T A+ I+GF+ EE+ + K+ +V+ GN+ FK+++ +QA A K
Sbjct: 328 QDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQK 387
Query: 385 TAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRI 444
+LMG+N +D +++ PR+KVG + V K QT +Q AV AL+K+ YE+LF W++TR+
Sbjct: 388 VCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRV 447
Query: 445 NQQLDTKLPRQ--HFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 502
N+ LD K RQ F+G+LDIAGFEIFE NS EQLCIN+TNEKLQQ FNH MF+LEQEEY
Sbjct: 448 NKALD-KTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 506
Query: 503 KKEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLG 559
++EGIEW FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G
Sbjct: 507 QREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-G 565
Query: 560 KSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLA 619
FQKPK +K + E FS+IHYAG VDY+ S WL KN DPLN+ V L SS++ +A
Sbjct: 566 SHPKFQKPKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVA 623
Query: 620 HLYATF--------ATADADSGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFV 671
L+ +S +K K F+TV L++E L KLM+ LR T P+FV
Sbjct: 624 DLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFV 683
Query: 672 RCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAI 731
RCIIPN K G ++ LVL QLRCNGVLEGIRICR+GFPNRI++ +F+QRY +L A+AI
Sbjct: 684 RCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAI 743
Query: 732 PEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQA 791
P+G F+D K+AC ++ ++++D Y+ G +K+FF+ G+L LEE RD ++ +I QA
Sbjct: 744 PKG-FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQA 802
Query: 792 VCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMA 851
+CRG+L R F K Q+ ++ IQ N +++ +++W W +LF K+KPLL+ E+EM
Sbjct: 803 MCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQ 862
Query: 852 TMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIK 911
++E QKTK+ K+E + KELE+K L +EKN LQ Q+QAE+E +AEE +L
Sbjct: 863 AKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAA 922
Query: 912 AKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHA 971
K +LE + E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK
Sbjct: 923 KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVT 982
Query: 972 TENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQ 1031
E K+K L +E+ +D+ KL++E+K L+E +L EE+K +L K K+K E
Sbjct: 983 AEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESM 1042
Query: 1032 VEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQL 1091
+ +LE L++E+K R +LE+ KRKLEGD E I DL+ +L +L KK+ E
Sbjct: 1043 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 1102
Query: 1092 QSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERL 1151
++++DE KKI+EL+ I +L+E++++ERA R K EKQ+ D ELE L L
Sbjct: 1103 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 1162
Query: 1152 EEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNL 1211
E+ T+TQ EL KRE E L++ L+E T HEA V +R+KHA +V EL EQ++
Sbjct: 1163 EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQF 1222
Query: 1212 QRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSL 1271
+R K L+K K + E DL+ + + ++K +E + LE Q+ E + K + +R+
Sbjct: 1223 KRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERAR 1282
Query: 1272 SELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALA 1331
+EL + +LQ E ++ L E E +L++ + + Q ++ + L+EE + K ++
Sbjct: 1283 AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVS 1342
Query: 1332 HALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAK 1391
L+ + + L++Q +EE E K L+R +S N +++ + K + D E LEE K
Sbjct: 1343 TKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGK 1401
Query: 1392 KKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFD 1451
K+ + +++ +Q E A LEKTK RLQ E++DL+VD++ L + L+KKQR FD
Sbjct: 1402 KRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFD 1461
Query: 1452 KVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIA 1511
++LAE K + E + + E+R T+ L A EEAL+ E ++R NK L+ E+
Sbjct: 1462 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1521
Query: 1512 DLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKS 1571
DL + GK +HELEKS++ +E + +++ LEE E L+ E LR+++ + +K
Sbjct: 1522 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKG 1581
Query: 1572 EIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLS 1631
+ +R + +DE+ E+ +R QR + ++ L+ E + R A KKK+EGDL ++E+Q
Sbjct: 1582 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1641
Query: 1632 HANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRA 1691
A + E +K LR +Q Q+KD Q L+DA ++++ E++A L+A++ +L+
Sbjct: 1642 SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQE 1701
Query: 1692 TLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARN 1751
L ERARK A+ E + E + + +L K++LE + QL+ E+E+ +
Sbjct: 1702 DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA 1761
Query: 1752 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKK 1811
++ +KA A ++ EL E+ T+ E ++ LE+ K+L+ +L E E K
Sbjct: 1762 MSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKS 1821
Query: 1812 QIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDK 1871
I LE +I +LE ++E E ++ + K L++ ++++KE+ Q E++RK + ++ +K
Sbjct: 1822 TIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEK 1881
Query: 1872 LQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTR 1926
+VK KRQ EEA+E++ RK Q EL+EA E + +VN L++K R
Sbjct: 1882 GNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 131 bits (330), Expect = 6e-30
Identities = 124/538 (23%), Positives = 251/538 (46%), Gaps = 51/538 (9%)
Query: 1404 QVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEE 1463
Q E + AK L+KTK+R Q + E+ + ++E+ +S ++K +++ AE + E
Sbjct: 857 QEEEMQAKEDELQKTKERQQ-KAENELKELEQKHSQLT--EEKNLLQEQLQAETELYAEA 913
Query: 1464 SQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKT 1523
+ + + K+ + L L +++ EE D+ + ++ E K + Q++ DL EQ+ E
Sbjct: 914 EEMRVRLAAKK-QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE--- 969
Query: 1524 IHELEKSRKQIELEKADIQLALEEAE---AALEHEEAKILRIQLELTQVKSEIDRKIAEK 1580
E +R++++LEK + +++ E ++ + K+ + + L + S++ +AE+
Sbjct: 970 ----EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1025
Query: 1581 DEE---IEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQA 1637
+E+ + +LK ++ + ++ L E +SR E +LK+K+EGD ++ Q++ Q
Sbjct: 1026 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1085
Query: 1638 AETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTE 1697
AE L + +L+ LDD + + + +++ +E + LQ +++ RA
Sbjct: 1086 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA------ 1139
Query: 1698 RARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAK 1757
AR AE++ K+ L +L L++E+ED +E
Sbjct: 1140 -ARNKAEKQ---------------------KRDLGEELEALKTELEDTLDSTATQQELRA 1177
Query: 1758 KAITDAAMMAEELKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1816
K + ++ + L +E + A ++ M++ Q V++L +L++ ++ K + Q L
Sbjct: 1178 KREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK-QTL 1236
Query: 1817 ETRIRELEFELE--GEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQV 1874
E +L EL G+ K+ E K +K E +V+EL + + + L D V KLQ
Sbjct: 1237 EKENADLAGELRVLGQAKQEVEHKK--KKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1294
Query: 1875 KVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSSR 1932
+V+S EA+ +A +L++ +E Q + K R R
Sbjct: 1295 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1352
Score = 79.0 bits (193), Expect = 4e-14
Identities = 75/314 (23%), Positives = 138/314 (43%), Gaps = 21/314 (6%)
Query: 1616 KKKMEGDLNEIEIQLSHANRQAAET-LKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAI 1674
+++ E E E+Q + +Q AE LK L QL + + L + L+ + +L
Sbjct: 856 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETEL------ 909
Query: 1675 VERRANLLQAEVEELRATLEQTERARKLAEQELLDSNE-RVQLLHTQNTSLIHTKKKLET 1733
AE EE+R L A+K +E+L E R++ + L +KK+
Sbjct: 910 --------YAEAEEMRVRLA----AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQ 957
Query: 1734 DLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKD 1793
++ L+ ++E+ + + + A + +E+ D + L + +K LE+ + D
Sbjct: 958 QMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1017
Query: 1794 LQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTY 1853
L L E E+ A K K K E+ I ELE L+ E+K E K RK E +
Sbjct: 1018 LTTNLAEEEEKA-KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1076
Query: 1854 QSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADI 1913
Q + + + L+ + K + ++++ + ++ Q N L K R+ + + + +E D
Sbjct: 1077 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDS 1136
Query: 1914 AESQVNKLRAKTRD 1927
+ NK + RD
Sbjct: 1137 ERAARNKAEKQKRD 1150
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 1405 bits (3637), Expect = 0.0
Identities = 776/1925 (40%), Positives = 1185/1925 (61%), Gaps = 28/1925 (1%)
Query: 27 AQNQPFDAKTYCFVVDSKEEYAKGKIKSSQDGKVTVETEDN-RTLVVKPEDVYAMNPPKF 85
A + AK ++ + + IK + +V VE +N + +V +D+ MNPPKF
Sbjct: 25 ATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKF 84
Query: 86 DRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRG 145
++EDMA LT LNE +VL+NLKDRY S +IYTYSGLFCV +NPYK LP+Y+ ++E YRG
Sbjct: 85 SKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRG 144
Query: 146 KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDL 205
KKR E PPHI++IS++AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A++
Sbjct: 145 KKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHK- 203
Query: 206 AKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 265
+KD + G LE Q++ ANP+LE+FGNAKTV+NDNSSRFGKFIRI+F TG + A+IE
Sbjct: 204 -GRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 262
Query: 266 TYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL-IELLLITTNPYDYPFISQGEILVASI 324
TYLLEKSR Q K ER++HIFYQ+LS L +LLL N +Y F+S G I +
Sbjct: 263 TYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFN--NYRFLSNGYIPIPGQ 320
Query: 325 DDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADK 384
D + T A+ I+GF+ EE + K+ +V+ +GN+ FK+++ +QA VA K
Sbjct: 321 QDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQK 380
Query: 385 TAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRI 444
+L+G+N + +A+ PR+KVG +YV K QT +Q AV AL+K+ YE+LF W+V RI
Sbjct: 381 LCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRI 440
Query: 445 NQQLD-TKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 503
N+ LD TK FIG+LDIAGFEIFE NS EQLCIN+TNEKLQQ FNH MF+LEQEEY+
Sbjct: 441 NKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQ 500
Query: 504 KEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGK 560
+EGIEW FIDFG+DL CI+LIE+P G+ ++L+EEC FPKATD +F KL Q G
Sbjct: 501 REGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLV-QEQGS 559
Query: 561 SNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAH 620
+ FQKP+ +K +A+ F +IHYAG VDY WL KN DPLN+ V L +SS+R +A
Sbjct: 560 HSKFQKPRQLKDKAD--FCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAE 617
Query: 621 LYAT---FATADADSGKKKVA-----KKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVR 672
L+ D +G + A K K F+TV L++E+L KLM+ LR T+P+FVR
Sbjct: 618 LWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVR 677
Query: 673 CIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIP 732
CIIPN K G ++ LVL QLRCNGVLEGIRICR+GFPNRI++ +F+QRY +L +AIP
Sbjct: 678 CIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIP 737
Query: 733 EGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAV 792
+G F+D K+ACE+++ ++++D Y+ G +K+FF+AG+L LEE RD ++ +I QAV
Sbjct: 738 KG-FMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAV 796
Query: 793 CRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMAT 852
CRG+L R F K Q+ ++ +Q N +++ ++HW W ++F K+KPLL+ E+E+
Sbjct: 797 CRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQA 856
Query: 853 MKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKA 912
EE K K++ K E + +E+E K L++EKN L Q+QAE+E +AEE +L
Sbjct: 857 KDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAK 916
Query: 913 KFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 972
K +LE + ++ R E+EEE N L +K+K++ +L++ +D+ E K++ EK
Sbjct: 917 KQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTA 976
Query: 973 ENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQV 1032
E K+K + EE+ L++ +K +EKK +++ + L EE+K +L K ++K E +
Sbjct: 977 EAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMI 1036
Query: 1033 EDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQ 1092
DLE L++E+K R +LE+ KRKL+G+ Q+ I +L+ +L +L KK+ E
Sbjct: 1037 SDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGAL 1096
Query: 1093 SKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLE 1152
++ +DE K ++ELQA+I EL+E+ E+E+A+R K EKQ+ D + ELE L LE
Sbjct: 1097 ARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELE 1156
Query: 1153 EAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQ 1212
+ T+ Q EL KRE E +L++ LEE T HEA + +R++HA ++ EL EQ++ +
Sbjct: 1157 DTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAK 1216
Query: 1213 RVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLS 1272
R K LEK K + + +L+ ++ + + KA E + L+ Q+ E K E R
Sbjct: 1217 RFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRV 1276
Query: 1273 ELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAH 1332
EL + S+LQ E +S LEE E + ++ + Q ++ + L+EE + K L+
Sbjct: 1277 ELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSS 1336
Query: 1333 ALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK 1392
++ + + L+EQ EEE+E + L++ + S++A + K + D + E LEEAKK
Sbjct: 1337 RIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD-LGTIESLEEAKK 1395
Query: 1393 KLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDK 1452
KL + + +++E LEKTK RLQ E++DL VD++ +A+ L+KKQ+ FD+
Sbjct: 1396 KLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQ 1455
Query: 1453 VLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIAD 1512
+LAE K+ E + + E+R T+ L A EEAL+ E +R+NK L ++ D
Sbjct: 1456 LLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMED 1515
Query: 1513 LTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSE 1572
L + GK +HELEKS++ +E + +++ LEE E L+ E LR+++ + +K++
Sbjct: 1516 LMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQ 1575
Query: 1573 IDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSH 1632
+R + +DE+ E+ KR + V +++ L+ E + R A+ KKKME DL ++E Q+
Sbjct: 1576 FERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEA 1635
Query: 1633 ANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRAT 1692
AN+ E +K LR +Q Q+KD Q L++A ++++ Q E++ L+AE+ +L+
Sbjct: 1636 ANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEE 1695
Query: 1693 LEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNA 1752
L +ERAR+ AEQE + + + + ++L+ K++LE + QL+ E+E+ +
Sbjct: 1696 LASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELL 1755
Query: 1753 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQ 1812
++ +K + EL E+ + + ++ LE+ K+L+ +L E E K
Sbjct: 1756 NDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKAT 1815
Query: 1813 IQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKL 1872
I LE +I +LE +LE E K+ + K +R+ E+++KE+ Q E++R++ + ++ ++K
Sbjct: 1816 ISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKA 1875
Query: 1873 QVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTR-----D 1927
++K KRQ EEA+E+A RK Q EL++A E + +V+ L+ + R
Sbjct: 1876 NARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPIS 1935
Query: 1928 FTSSR 1932
F+SSR
Sbjct: 1936 FSSSR 1940
Score = 128 bits (322), Expect = 5e-29
Identities = 121/542 (22%), Positives = 246/542 (45%), Gaps = 55/542 (10%)
Query: 1417 KTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESR 1476
+ ++ LQ + E+L+ E+ + L++ +R ++L E E+ QAE E E+
Sbjct: 849 RQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETEL-FAEAE 907
Query: 1477 SLSTELFKLKNAYEEALDQLET-----------VKRENKNLEQEIADLTEQIAENGKTIH 1525
+ L K EE L LE+ ++ E K ++ I DL EQ+ E
Sbjct: 908 EMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEE----- 962
Query: 1526 ELEKSRKQIELEKADIQLALEEAEAA---LEHEEAKILRIQLELTQVKSEIDRKIAEKDE 1582
E +R++++LEK + +++ E LE + +K ++ + + +E ++AE++E
Sbjct: 963 --EGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEE 1020
Query: 1583 EIEQLK--RNYQRT-VETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAE 1639
+ + L RN Q + ++ L E ++R E + K+K++G+ +++ Q++ Q E
Sbjct: 1021 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDE 1080
Query: 1640 TLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERA 1699
L + +L+ DD E L + A+ R LQA++ EL+ E + +
Sbjct: 1081 LKLQLAKKEEELQGALARGDD-----ETLHKNNALKVVRE--LQAQIAELQEDFESEKAS 1133
Query: 1700 RKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKA 1759
R AE++ K+ L +L L++E+ED +E K
Sbjct: 1134 RNKAEKQ---------------------KRDLSEELEALKTELEDTLDTTAAQQELRTKR 1172
Query: 1760 ITDAAMMAEELKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLET 1818
+ A + + L++E ++ A ++ M++ +++L +L++A++ K + Q LET
Sbjct: 1173 EQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNK-QGLET 1231
Query: 1819 RIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKS 1878
+EL E++ Q+ ES +K + +V+EL + E + + L + KLQ ++ +
Sbjct: 1232 DNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDN 1291
Query: 1879 YKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHES 1938
EEA+++ + +L++ +E Q L ++ R + + E
Sbjct: 1292 VSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQ 1351
Query: 1939 EE 1940
+E
Sbjct: 1352 QE 1353
Score = 116 bits (291), Expect = 2e-25
Identities = 134/566 (23%), Positives = 245/566 (43%), Gaps = 117/566 (20%)
Query: 838 KPLLKSAETE----KEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQ 893
K LLK AE +E A ++ +KTK+ L ++EL++ V L D Q QV
Sbjct: 1395 KKLLKDAEALSQRLEEKALAYDKLEKTKNRL------QQELDDLTVDL-----DHQRQV- 1442
Query: 894 AESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEE------------------EINA 935
+ NL +++ DQL+ + + A+ E +RAE E E
Sbjct: 1443 --ASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKE 1500
Query: 936 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTR 995
E + ++L + +L DD+ + ++EK K A E +V+ + +L L++ + + T
Sbjct: 1501 EFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDEL-QATE 1559
Query: 996 EKKALQEAHQQALD-----DLQAEEDKVNSLNKTKSKLE-QQVEDLESSLEQEKKLRVDL 1049
+ K E + QA+ DLQ +++ N+ K +L +QV +LE+ LE E+K R
Sbjct: 1560 DAKLRLEVNMQAMKAQFERDLQTRDEQ----NEEKKRLLIKQVRELEAELEDERKQRALA 1615
Query: 1050 ERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTL-------G 1102
+K+K+E DLK + I + ++ ++L+K + Q ++E+ +
Sbjct: 1616 VASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQS 1675
Query: 1103 LQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELE----------------- 1145
+ +KK+K L+A I +L+EE+ + R E++R + A E+
Sbjct: 1676 KESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLE 1735
Query: 1146 ----ELSERLEEAGG----------VTSTQIE-LNKKREAEFL----------KLRRDLE 1180
+L E LEE T+ Q++ LN + AE +L R +
Sbjct: 1736 ARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNK 1795
Query: 1181 EATLQHEAMVAALRKKHADSVAELGEQIDNLQ--------------RVKQKLEKEKSEFK 1226
E + + + A++ K +++ L +I L+ ++ ++ EK+ E
Sbjct: 1796 ELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIF 1855
Query: 1227 LEIDD----LSSSMESVSKSKANLEKICRTLEDQLSEARGKN---EEIQRSLSELTTQKS 1279
++++D E + K+ A ++++ R LE+ EA N ++QR L + T
Sbjct: 1856 MQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANE 1915
Query: 1280 RLQTEAGELSRQLEEKESIVSQLSRS 1305
L E L +L I SRS
Sbjct: 1916 GLSREVSTLKNRLRRGGPISFSSSRS 1941
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 1397 bits (3617), Expect = 0.0
Identities = 772/1907 (40%), Positives = 1168/1907 (61%), Gaps = 26/1907 (1%)
Query: 34 AKTYCFVVDSKEEYAKGKIKSSQDGKVTVE-TEDNRTLVVKPEDVYAMNPPKFDRIEDMA 92
AK +V K + +K + VE E+ + + V +D+ MNPPKF ++EDMA
Sbjct: 28 AKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMA 87
Query: 93 MLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAP 152
LT LNE +VL+NLK+RY S +IYTYSGLFCV +NPYK LP+Y+ E+VE Y+GKKR E P
Sbjct: 88 ELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMP 147
Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSK 212
PHI++I+D AY+ M+ DRE+QSIL TGESGAGKT NTK+VIQY A +A++ K K
Sbjct: 148 PHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASS-----HKSKK 202
Query: 213 MKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKS 272
+G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLEKS
Sbjct: 203 DQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKS 262
Query: 273 RVTFQLKAERSYHIFYQILSNKKPELIELLLITTNPYD-YPFISQGEILVASIDDAEELL 331
R Q K ER++HIFY +LS L LL+ PY+ Y F+S G + + D +
Sbjct: 263 RAIRQAKEERTFHIFYYLLSGAGEHLKTDLLL--EPYNKYRFLSNGHVTIPGQQDKDMFQ 320
Query: 332 ATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLMGL 391
T A+ I+G EE+ GL ++ V+ GN+ FK+++ +QA A K ++L+G+
Sbjct: 321 ETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGI 380
Query: 392 NSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLD-T 450
N +D + + PR+KVG +YV K QT +Q A+ AL+K+ YE++F W+V RIN+ LD T
Sbjct: 381 NVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKT 440
Query: 451 KLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWT 510
K FIG+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 441 KRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWN 500
Query: 511 FIDFGMDLAACIELIEKPMG---IFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKP 567
FIDFG+DL CI+LIEKP G I ++L+EEC FPKATD SF K+ Q G FQKP
Sbjct: 501 FIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVM-QEQGTHPKFQKP 559
Query: 568 KVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYAT--- 624
K +K +A+ F +IHYAG VDY WL KN DPLN+ + L +SS++ ++ L+
Sbjct: 560 KQLKDKAD--FCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDR 617
Query: 625 FATADADSGKKKVA-----KKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNET 679
D +G + A K + F+TV L++E L KLM+ LR T+P+FVRCIIPN
Sbjct: 618 IIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHE 677
Query: 680 KTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDS 739
K G ++ LVL QLRCNGVLEGIRICR+GFPNR+++ +F+QRY +L ++IP+G F+D
Sbjct: 678 KKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKG-FMDG 736
Query: 740 KKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLMR 799
K+AC ++ ++++D Y+ G +KVFF+AG+L LEE RD ++ +I QA CRG+L R
Sbjct: 737 KQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLAR 796
Query: 800 VEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQK 859
F K Q+ ++ +Q N +++ +++W W +LF K+KPLL+ + E+EM +EE K
Sbjct: 797 KAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVK 856
Query: 860 TKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAK 919
+++ +E + E+E L+ EK LQ Q+QAE+E +AEE +L K +LE
Sbjct: 857 VREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEI 916
Query: 920 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 979
++ R E+EEE L A+K+K++ EL++ +++ E K++ EK TE K+K L
Sbjct: 917 CHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKL 976
Query: 980 TEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSL 1039
EE L++ KL +EKK L++ + +L EE+K SL K K+K E + DLE L
Sbjct: 977 EEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERL 1036
Query: 1040 EQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQ 1099
+E+K R +LE+ +RKLEGD + I +L+ +L +L KK+ E ++VE+E
Sbjct: 1037 RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEA 1096
Query: 1100 TLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTS 1159
KKI+EL+++I EL+E++E+ERA+R K EKQ+ D ELE L LE+ T+
Sbjct: 1097 AQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 1156
Query: 1160 TQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLE 1219
Q EL KRE E L++ LEE HEA + +R+KH+ +V EL EQ++ +RVK LE
Sbjct: 1157 AQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLE 1216
Query: 1220 KEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKS 1279
K K + E +L++ ++ + + K + E + +E QL E + K E +R +EL + +
Sbjct: 1217 KAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVT 1276
Query: 1280 RLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRH 1339
+LQ E ++ L + +S S+L++ A Q ++ + L+EEN+ K +L+ L+
Sbjct: 1277 KLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVED 1336
Query: 1340 DCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1399
+ + REQ EEE+E K L++ ++ +++VA + K E D++ E EE K+KL + L+
Sbjct: 1337 EKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME-DSVGCLETAEEVKRKLQKDLE 1395
Query: 1400 DSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKT 1459
++ E A LEKTK RLQ E++DL+VD++ A L+KKQ+ FD++LAE KT
Sbjct: 1396 GLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKT 1455
Query: 1460 KCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAE 1519
+ E + + E+R T+ L A EEA++Q ++R NK E+ DL +
Sbjct: 1456 ISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDD 1515
Query: 1520 NGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAE 1579
GK++HELEKS++ +E + +++ LEE E L+ E LR+++ L +K++ +R +
Sbjct: 1516 VGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQG 1575
Query: 1580 KDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAE 1639
+DE+ E+ K+ R V M++ L+ E + R+ A+ +KK+E DL ++E + AN+ E
Sbjct: 1576 RDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDE 1635
Query: 1640 TLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERA 1699
+K LR +Q Q+KD LDD +E++ Q E++ ++AE+ +L+ L ERA
Sbjct: 1636 AIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERA 1695
Query: 1700 RKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKA 1759
++ A+QE + + + + + K++LE + QL+ E+E+ + ++ KKA
Sbjct: 1696 KRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKA 1755
Query: 1760 ITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETR 1819
+ +L E+ + E ++ LE+ K+L+ +L E E K I LE +
Sbjct: 1756 NLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAK 1815
Query: 1820 IRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSY 1879
I +LE +L+ E K+ + K +R+ E+++K++ Q +++R+N + +D DK ++K
Sbjct: 1816 IAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQL 1875
Query: 1880 KRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTR 1926
KRQ EEA+E+A RK Q ELE+A E AD +V+ L+ K R
Sbjct: 1876 KRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
Score = 157 bits (397), Expect = 1e-37
Identities = 142/642 (22%), Positives = 288/642 (44%), Gaps = 43/642 (6%)
Query: 842 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLD 901
KS++ K+ + ++ + Q T++ L + ++ L KL + EKN + Q++ E E +
Sbjct: 1295 KSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHN 1354
Query: 902 AEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAEL--------------TAKKRKLEDE 947
E++ L ++ K+++ E EE+ +L A KLE
Sbjct: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414
Query: 948 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREK-KALQEAHQQ 1006
+ L++++DDL + L + E K K + L+ AK E+ +A EA ++
Sbjct: 1415 KTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREK 1474
Query: 1007 ---------ALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLE 1057
AL++ ++ ++ LNK + ++EDL SS + K +LE++KR LE
Sbjct: 1475 ETKALSLARALEEAMEQKAELERLNK---QFRTEMEDLMSSKDDVGKSVHELEKSKRALE 1531
Query: 1058 GDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVE-DEQTLGLQFQKKIKELQARI 1116
++ + + +LE++ Q ++ + + ++++ E D Q Q ++K K+L ++
Sbjct: 1532 QQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQV 1591
Query: 1117 EELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLR 1176
E+E E+E ER R+ R +L++L ++ A I+ +K +A+
Sbjct: 1592 REMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCM 1651
Query: 1177 RDLEEATLQHEAMVAALR------KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEID 1230
R+L++ E ++A + K + +L E++ +R K++ ++E+ E EI
Sbjct: 1652 RELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIA 1711
Query: 1231 DLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSR 1290
+ S + K LE LE++L E +G E I L + Q ++ T+
Sbjct: 1712 NSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERS 1771
Query: 1291 QLEEKESIVSQLSRSKQAFTQQTEELKRQLEE-ENKAKNALAHALQSSRHDCDLLREQYE 1349
++ E+ QL R Q +ELK +L+E E K+ ++ + L EQ +
Sbjct: 1772 HAQKNENARQQLER-------QNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLD 1824
Query: 1350 EEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVN 1409
E + + + + + ++ + + D + E+ ++ K + RL+ + Q+E
Sbjct: 1825 NETKERQAACKQVRRTEKKLKDVLLQVD-DERRNAEQYKDQADKASTRLKQLKRQLEEAE 1883
Query: 1410 AKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFD 1451
+ ++++LQ E+ED + N ++L K R D
Sbjct: 1884 EEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925
Score = 82.4 bits (202), Expect = 4e-15
Identities = 78/305 (25%), Positives = 145/305 (47%), Gaps = 31/305 (10%)
Query: 1627 EIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEV 1686
E QL+ NR L + ++Q QL +L L + L+ + +L + + R + E+
Sbjct: 859 EKQLAAENR-----LTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQEL 913
Query: 1687 EELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDAS 1746
EE+ LE ++ E+E ER Q L + KKK++ ++ +L+ ++E+
Sbjct: 914 EEICHDLEA-----RVEEEE-----ERCQHLQAE-------KKKMQQNIQELEEQLEE-- 954
Query: 1747 RDARNAEEKAKKAITDAAMMAEELKKEQ----DTSAHLERMKKNLEQTVKDLQHRLDEAE 1802
++ + + +K T+A + ++L++EQ D + L + KK LE + + L E E
Sbjct: 955 EESARQKLQLEKVTTEAKL--KKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEE 1012
Query: 1803 QLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNV 1862
+ + K K K E I +LE L E+K+ E K RK E +L+ Q E + +
Sbjct: 1013 EKS-KSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQI 1071
Query: 1863 LRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLR 1922
L+ + K + ++++ + EE Q N L K R+ + ++ E +E + + NK
Sbjct: 1072 AELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAE 1131
Query: 1923 AKTRD 1927
+ RD
Sbjct: 1132 KQKRD 1136
Score = 64.3 bits (155), Expect = 1e-09
Identities = 64/273 (23%), Positives = 131/273 (47%), Gaps = 33/273 (12%)
Query: 840 LLKSAETEKEMATMKEEFQKTKDELAKSE-AKRKELEE-------------KLVTLVQEK 885
L ++ E EK++ +M+ E + ++ELA +E AKR+ +E K ++EK
Sbjct: 1665 LAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEK 1724
Query: 886 NDLQLQVQAESENLLDAEERC----DQLIKAKFQLEAKIKEVT-ERAEDEEEINAELTAK 940
L+ ++ E L + + D+L KA Q++ ++ ER+ ++ NA
Sbjct: 1725 RRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENA----- 1779
Query: 941 KRKLEDECSELKKDIDDLELTL-AKVEKEKHATENKVKNLTEELSG----LDETIAKLTR 995
+++LE + ELK + ++E T+ +K + A E K+ L E+L ++ R
Sbjct: 1780 RQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRR 1839
Query: 996 EKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRK 1055
+K L++ Q D+ + E + +K ++L+Q LE + E+ ++ ++RK
Sbjct: 1840 TEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANA----SRRK 1895
Query: 1056 LEGDLKLAQESILDLENDKQQLDERLKKKDFEY 1088
L+ +L+ A E+ + + L +L++ D +
Sbjct: 1896 LQRELEDATETADAMNREVSSLKNKLRRGDLPF 1928
Score = 62.8 bits (151), Expect = 3e-09
Identities = 65/299 (21%), Positives = 122/299 (40%), Gaps = 39/299 (13%)
Query: 1668 LKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHT 1727
+K L + + ++ E E ++ +Q +L E E L S + L Q T
Sbjct: 834 VKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAET 893
Query: 1728 ----------------KKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELK 1771
K++LE L++ VE+ ++ + + KK + + E+L+
Sbjct: 894 ELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLE 953
Query: 1772 KEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK----LETRIRELEFEL 1827
+E+ L+ K E +K L E EQ+ L+ ++ K LE RI E L
Sbjct: 954 EEESARQKLQLEKVTTEAKLKKL-----EEEQIILEDQNCKLAKEKKLLEDRIAEFTTNL 1008
Query: 1828 EGEQKKNTESVKGLRKYERRVKEL--TYQSEEDRKNVLR------------LQDLVDKLQ 1873
E++K+ K K+E + +L + EE ++ L L D + +LQ
Sbjct: 1009 TEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQ 1068
Query: 1874 VKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSSR 1932
++ K Q + +E+ A L + + + A ++ ESQ+++L+ +SR
Sbjct: 1069 AQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASR 1127
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 1303 bits (3371), Expect = 0.0
Identities = 728/1908 (38%), Positives = 1146/1908 (60%), Gaps = 28/1908 (1%)
Query: 34 AKTYCFVVDSKEEYAKGKIKSSQDGKVTVE-TEDNRTLVVKPEDVYAMNPPKFDRIEDMA 92
A+ +V + ++ + + VE E R L + + + MNPPKF + EDMA
Sbjct: 52 ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111
Query: 93 MLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAP 152
LT LNE +VL+NL++RY S +IYTYSGLFCV +NPYK LP+Y +VE YRGKKR E P
Sbjct: 112 ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171
Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSK 212
PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A++ +K+
Sbjct: 172 PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPK--GRKEPG 229
Query: 213 MKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKS 272
+ G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLEKS
Sbjct: 230 VPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKS 289
Query: 273 RVTFQLKAERSYHIFYQILSNKKPELIELLLITTNPYDYPFISQGEILVASIDDAEELLA 332
R Q K E S+HIFYQ+L +L LL+ + Y F++ G + E
Sbjct: 290 RAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERELFQE 347
Query: 333 TDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLN 392
T ++ +LGF+ EE + ++ AV+ +GN+ K+++ +QA A K L+GL
Sbjct: 348 TLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLG 407
Query: 393 SSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLDTKL 452
+D +AL PR+KVG +YV K QT +Q A+ AL+K+ YE+LF W+V R+N+ LD +
Sbjct: 408 VTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD-RS 466
Query: 453 PRQ--HFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWT 510
PRQ F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI WT
Sbjct: 467 PRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWT 526
Query: 511 FIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKP 567
F+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ Q G FQ+P
Sbjct: 527 FLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGHPKFQRP 585
Query: 568 KVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYATFAT 627
+ ++ +A+ FS++HYAG VDY + WL KN DPLN+ V L +S++RL A ++
Sbjct: 586 RHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD--- 640
Query: 628 ADADSGKKKVA---------KKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNE 678
+ G ++V+ + + F+TV L++E+L++LM+ L T+P FVRCI+PN
Sbjct: 641 VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNH 700
Query: 679 TKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFID 738
K G +E LVL QLRCNGVLEGIRICR+GFPNRIL+ +F+QRY +L +AIP+G F+D
Sbjct: 701 EKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMD 759
Query: 739 SKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLM 798
K+ACEK++ ++++D Y+ G +K+FF+AG+L LEE RD ++ +I QA RG+L
Sbjct: 760 GKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLA 819
Query: 799 RVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 858
R FQK Q++ ++ +Q N +++ ++HW W +LF K+KPLL+ ++ + +E Q
Sbjct: 820 RRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQ 879
Query: 859 KTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEA 918
K ++ +S + EL+ ++ L +E+ L Q++AE+E +AEE +L K +LE
Sbjct: 880 KVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELEL 939
Query: 919 KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 978
+ E+ R +EEE + ++ +K++L+ EL+ ++ E K++ EK TE K+K
Sbjct: 940 VVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKK 999
Query: 979 LTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESS 1038
E+L L++ +KL++E+K L++ + EE+KV SLNK + K E + D+E
Sbjct: 1000 FEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDR 1059
Query: 1039 LEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDE 1098
L +E+K R +LE+ KR+L+G+ QE +++ + ++L +L +K+ E ++ EDE
Sbjct: 1060 LRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDE 1119
Query: 1099 QTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVT 1158
Q K ++E QA + E +E++E+ER R K EKQR D ELE L LE+ T
Sbjct: 1120 GGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDST 1179
Query: 1159 STQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKL 1218
+ Q EL KRE E +L++ LEE T HEA V LR++H ++ EL EQ++ +R K
Sbjct: 1180 NAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAW 1239
Query: 1219 EKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQK 1278
EK + + E+ +L + + S+ ++ E+ R LE QL E +G+ + +R+ +E +
Sbjct: 1240 EKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKL 1299
Query: 1279 SRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSR 1338
R Q E +S L E ES +LS+ + Q + + L+EE +AK AL +++
Sbjct: 1300 QRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAME 1359
Query: 1339 HDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1398
+ LREQ EEE + R L A +++++WR + E +A E EEA+++ A+
Sbjct: 1360 AEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREA 1418
Query: 1399 QDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWK 1458
+ +++ LE+ ++RLQ E++D +D+E+ L + L+KKQR FD++LAE K
Sbjct: 1419 EALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEK 1478
Query: 1459 TKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIA 1518
+ E E + E R L A EE + E ++R+N+ L E+ L
Sbjct: 1479 AAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKD 1538
Query: 1519 ENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIA 1578
+ GK++HELE++ + E D++ + E E L E LR+++ + +K++ +R +
Sbjct: 1539 DVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQ 1598
Query: 1579 EKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAA 1638
+DE E+ +R + + + D E + R A+ +KK+EG+L E++ Q++ A +
Sbjct: 1599 GRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKE 1658
Query: 1639 ETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTER 1698
E +K LR +Q Q+K+ +++ +E++ Q E+R L+AEV L+ L ++R
Sbjct: 1659 EAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDR 1718
Query: 1699 ARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKK 1758
AR+ A+Q+ + + V + +++ K++LE L QL+ E+E+ ++ ++ +K
Sbjct: 1719 ARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRK 1778
Query: 1759 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLET 1818
+ + EL E+ SA E ++ LE+ +++L+ RL E + A K I LE+
Sbjct: 1779 LLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALES 1838
Query: 1819 RIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKS 1878
++ + E +LE E ++ S K +R+ E+R+KE+ Q EE+R+ +L+D ++K ++VK
Sbjct: 1839 KLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQ 1898
Query: 1879 YKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTR 1926
KRQ EEA+E+A+ R+ Q ELE+ E A+ +V LR + R
Sbjct: 1899 LKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1946
Score = 124 bits (311), Expect = 9e-28
Identities = 163/721 (22%), Positives = 313/721 (43%), Gaps = 81/721 (11%)
Query: 1269 RSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKN 1328
+ L ++T Q LQ A EL + V +L + + + QLEEE +
Sbjct: 859 KPLLQVTRQDEVLQARAQELQK--------VQELQQQSAREVGELQGRVAQLEEE---RA 907
Query: 1329 ALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELE 1388
LA L++ C E K EL+ +S+ + V + + + +++
Sbjct: 908 RLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEE--------ECSRQMQ 959
Query: 1389 EAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQR 1448
KK+L Q +Q+ E +EA L+ K + +++ D+ + L K+++
Sbjct: 960 TEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERK 1019
Query: 1449 NFDKVLAEWKTKCEESQAELEA----SLKESRSLSTELFKLKNAYEEALDQLETVKRENK 1504
+ LAE+ ++ E + ++++ LK +++ +L+ E+ +LE +KR
Sbjct: 1020 LLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE-EKGRQELEKLKRR-- 1076
Query: 1505 NLEQEIADLTEQIAENGKTIHEL--EKSRKQIELEKADIQLALEEAEAALEHEEAKILR- 1561
L+ E ++L EQ+ E + EL + RK+ EL+ A LA E E + K LR
Sbjct: 1077 -LDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAA---LARAEDEGGARAQLLKSLRE 1132
Query: 1562 IQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEG 1621
Q L + + +++ + + + E+ +R+ +E ++ L+ + S N L+ K E
Sbjct: 1133 AQAALAEAQEDLESERVARTKA-EKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQ 1191
Query: 1622 DLNEIEIQLSHANRQAAETLKHLRSVQGQ-LKDTQLHLDDALRGQEDLKEQLAIVERRAN 1680
++ E++ L R ++ LR GQ L + L+ A RG+ ++ +E +
Sbjct: 1192 EVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVS 1251
Query: 1681 LLQAEVEELRATLEQTERARKLAEQEL--------------LDSNERVQLLHTQNTSLIH 1726
L+AE+ L+ ++ E+ R+ E +L ++ E++Q + ++
Sbjct: 1252 ELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSG 1311
Query: 1727 TKKKLETDLMQLQSEVEDASRDARNAEE------KAKKAI--------TDAAMMAEELKK 1772
+ E+ ++L E+ +A+E +AK A+ +AA + E+L++
Sbjct: 1312 ALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEE 1371
Query: 1773 EQDTSAHLERMKKNLEQTVKDLQH--RLDEAEQLALKGGKKQIQKLETRIRELEFELEGE 1830
E +A ER + L+ L R E E AL+ G++ ++ L L +
Sbjct: 1372 E---AAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEK 1428
Query: 1831 QKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRL---QDLVDKLQVKVKSYKRQAEEAD 1887
+ +G R+ ++ + + T E+ R+ V L Q D+L + K+ +A E
Sbjct: 1429 TETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEER 1488
Query: 1888 EQANAHLTKFRKAQ-----HELEEAEERADIAESQVNKLRAKTRDFTSSR----MVVHES 1938
E+A A + R+A+ LEE +E + E Q LRA+ SS+ VHE
Sbjct: 1489 ERAEAE-GREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHEL 1547
Query: 1939 E 1939
E
Sbjct: 1548 E 1548
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 1298 bits (3359), Expect = 0.0
Identities = 728/1914 (38%), Positives = 1145/1914 (59%), Gaps = 32/1914 (1%)
Query: 34 AKTYCFVVDSKEEYAKGKIKSSQDGKVTVE-TEDNRTLVVKPEDVYAMNPPKFDRIEDMA 92
A+ +V + ++ + + VE E R L + + + MNPPKF + EDMA
Sbjct: 52 ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111
Query: 93 MLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAP 152
LT LNE +VL+NL++RY S +IYTYSGLFCV +NPYK LP+Y +VE YRGKKR E P
Sbjct: 112 ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171
Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKK--- 209
PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A++ K+
Sbjct: 172 PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP 231
Query: 210 ---DSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 266
+ G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IET
Sbjct: 232 ASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIET 291
Query: 267 YLLEKSRVTFQLKAERSYHIFYQILSNKKPELIELLLITTNPYDYPFISQGEILVASIDD 326
YLLEKSR Q K E S+HIFYQ+L +L LL+ + Y F++ G +
Sbjct: 292 YLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QE 349
Query: 327 AEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTA 386
E T ++ +LGF+ EE + ++ AV+ +GN+ K+++ +QA A K
Sbjct: 350 RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLC 409
Query: 387 YLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQ 446
L+GL +D +AL PR+KVG +YV K QT +Q A+ AL+K+ YE+LF W+V R+N+
Sbjct: 410 RLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNR 469
Query: 447 QLDTKLPRQ--HFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 504
LD + PRQ F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++
Sbjct: 470 ALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQR 528
Query: 505 EGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKS 561
EGI WTF+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ Q G
Sbjct: 529 EGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGH 587
Query: 562 NNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHL 621
FQ+P+ ++ +A+ FS++HYAG VDY + WL KN DPLN+ V L +S++RL A +
Sbjct: 588 PKFQRPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
Query: 622 YATFATADADSGKKKVA---------KKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVR 672
+ + G ++V+ + + F+TV L++E+L++LM+ L T+P FVR
Sbjct: 646 WKD---VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVR 702
Query: 673 CIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIP 732
CI+PN K G +E LVL QLRCNGVLEGIRICR+GFPNRIL+ +F+QRY +L +AIP
Sbjct: 703 CIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIP 762
Query: 733 EGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAV 792
+G F+D K+ACEK++ ++++D Y+ G +K+FF+AG+L LEE RD ++ +I QA
Sbjct: 763 KG-FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAA 821
Query: 793 CRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMAT 852
RG+L R FQK Q++ ++ +Q N +++ ++HW W +LF K+KPLL+ ++ +
Sbjct: 822 ARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQA 881
Query: 853 MKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKA 912
+E QK ++ +S + EL+ ++ L +E+ L Q++AE+E +AEE +L
Sbjct: 882 RAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAAR 941
Query: 913 KFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 972
K +LE + E+ R +EEE + ++ +K++L+ EL+ ++ E K++ EK T
Sbjct: 942 KQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTT 1001
Query: 973 ENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQV 1032
E K+K E+L L++ +KL++E+K L++ + EE+KV SLNK + K E +
Sbjct: 1002 EAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATI 1061
Query: 1033 EDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQ 1092
D+E L +E+K R +LE+ KR+L+G+ QE +++ + ++L +L +K+ E
Sbjct: 1062 ADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAAL 1121
Query: 1093 SKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLE 1152
++ EDE Q K ++E QA + E +E++E+ER R K EKQR D ELE L LE
Sbjct: 1122 ARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELE 1181
Query: 1153 EAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQ 1212
+ T+ Q EL KRE E +L++ LEE T HEA V LR++H ++ EL EQ++ +
Sbjct: 1182 DTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQAR 1241
Query: 1213 RVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLS 1272
R K EK + + E+ +L + + S+ ++ E+ R LE QL E +G+ + +R+ +
Sbjct: 1242 RGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARA 1301
Query: 1273 ELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAH 1332
E + R Q E +S L E ES +LS+ + Q + + L+EE +AK AL
Sbjct: 1302 EAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGS 1361
Query: 1333 ALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK 1392
+++ + LREQ EEE + R L A +++++WR + E +A E EEA++
Sbjct: 1362 RVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARR 1420
Query: 1393 KLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDK 1452
+ A+ + +++ LE+ ++RLQ E++D +D+E+ L + L+KKQR FD+
Sbjct: 1421 RAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQ 1480
Query: 1453 VLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIAD 1512
+LAE K + E E + E R L A EE + E ++R+N+ L E+
Sbjct: 1481 LLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA 1540
Query: 1513 LTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSE 1572
L + GK++HELE++ + E D++ + E E L E LR+++ + +K++
Sbjct: 1541 LLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQ 1600
Query: 1573 IDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSH 1632
+R + +DE E+ +R + + + D E + R A+ +KK+EG+L E++ Q++
Sbjct: 1601 HERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMAS 1660
Query: 1633 ANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRAT 1692
A + E +K LR +Q Q+K+ +++ +E++ Q E+R L+AEV L+
Sbjct: 1661 AGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1720
Query: 1693 LEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNA 1752
L ++RAR+ A+Q+ + + V + +++ K++LE L QL+ E+E+ ++
Sbjct: 1721 LAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELL 1780
Query: 1753 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQ 1812
++ +K + + EL E+ SA E ++ LE+ +++L+ RL E + A K
Sbjct: 1781 NDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMT 1840
Query: 1813 IQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKL 1872
I LE+++ + E +LE E ++ S K +R+ E+R+KE+ Q EE+R+ +L+D ++K
Sbjct: 1841 IAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKG 1900
Query: 1873 QVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTR 1926
++VK KRQ EEA+E+A+ R+ Q ELE+ E A+ +V LR + R
Sbjct: 1901 NLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1954
Score = 124 bits (311), Expect = 9e-28
Identities = 163/721 (22%), Positives = 313/721 (43%), Gaps = 81/721 (11%)
Query: 1269 RSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKN 1328
+ L ++T Q LQ A EL + V +L + + + QLEEE +
Sbjct: 867 KPLLQVTRQDEVLQARAQELQK--------VQELQQQSAREVGELQGRVAQLEEE---RA 915
Query: 1329 ALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELE 1388
LA L++ C E K EL+ +S+ + V + + + +++
Sbjct: 916 RLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEE--------ECSRQMQ 967
Query: 1389 EAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQR 1448
KK+L Q +Q+ E +EA L+ K + +++ D+ + L K+++
Sbjct: 968 TEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERK 1027
Query: 1449 NFDKVLAEWKTKCEESQAELEA----SLKESRSLSTELFKLKNAYEEALDQLETVKRENK 1504
+ LAE+ ++ E + ++++ LK +++ +L+ E+ +LE +KR
Sbjct: 1028 LLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE-EKGRQELEKLKRR-- 1084
Query: 1505 NLEQEIADLTEQIAENGKTIHEL--EKSRKQIELEKADIQLALEEAEAALEHEEAKILR- 1561
L+ E ++L EQ+ E + EL + RK+ EL+ A LA E E + K LR
Sbjct: 1085 -LDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAA---LARAEDEGGARAQLLKSLRE 1140
Query: 1562 IQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEG 1621
Q L + + +++ + + + E+ +R+ +E ++ L+ + S N L+ K E
Sbjct: 1141 AQAALAEAQEDLESERVARTKA-EKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQ 1199
Query: 1622 DLNEIEIQLSHANRQAAETLKHLRSVQGQ-LKDTQLHLDDALRGQEDLKEQLAIVERRAN 1680
++ E++ L R ++ LR GQ L + L+ A RG+ ++ +E +
Sbjct: 1200 EVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVS 1259
Query: 1681 LLQAEVEELRATLEQTERARKLAEQEL--------------LDSNERVQLLHTQNTSLIH 1726
L+AE+ L+ ++ E+ R+ E +L ++ E++Q + ++
Sbjct: 1260 ELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSG 1319
Query: 1727 TKKKLETDLMQLQSEVEDASRDARNAEE------KAKKAI--------TDAAMMAEELKK 1772
+ E+ ++L E+ +A+E +AK A+ +AA + E+L++
Sbjct: 1320 ALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEE 1379
Query: 1773 EQDTSAHLERMKKNLEQTVKDLQH--RLDEAEQLALKGGKKQIQKLETRIRELEFELEGE 1830
E +A ER + L+ L R E E AL+ G++ ++ L L +
Sbjct: 1380 E---AAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEK 1436
Query: 1831 QKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRL---QDLVDKLQVKVKSYKRQAEEAD 1887
+ +G R+ ++ + + T E+ R+ V L Q D+L + K+ +A E
Sbjct: 1437 TETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEER 1496
Query: 1888 EQANAHLTKFRKAQ-----HELEEAEERADIAESQVNKLRAKTRDFTSSR----MVVHES 1938
E+A A + R+A+ LEE +E + E Q LRA+ SS+ VHE
Sbjct: 1497 ERAEAE-GREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHEL 1555
Query: 1939 E 1939
E
Sbjct: 1556 E 1556
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 1288 bits (3333), Expect = 0.0
Identities = 730/1944 (37%), Positives = 1148/1944 (59%), Gaps = 59/1944 (3%)
Query: 34 AKTYCFVVDSKEEYAKGKIKSSQDGKVTVE-TEDNRTLVVKPEDVYAMNPPKFDRIEDMA 92
A+ +V + ++ + + VE E R L + + + MNPPKF + EDMA
Sbjct: 52 ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111
Query: 93 MLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAP 152
LT LNE +VL+NL++RY S +IYTYSGLFCV +NPYK LP+Y +VE YRGKKR E P
Sbjct: 112 ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171
Query: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKK--- 209
PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A++ K+
Sbjct: 172 PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP 231
Query: 210 ---DSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 266
+ G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IET
Sbjct: 232 ASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIET 291
Query: 267 YLLEKSRVTFQLKAERSYHIFYQILSNKKPELIELLLITTNPYDYPFISQGEILVASIDD 326
YLLEKSR Q K E S+HIFYQ+L +L LL+ + Y F++ G +
Sbjct: 292 YLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QE 349
Query: 327 AEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTA 386
E T ++ +LGF+ EE + ++ AV+ +GN+ K+++ +QA A K
Sbjct: 350 RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLC 409
Query: 387 YLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQ 446
L+GL +D +AL PR+KVG +YV K QT +Q A+ AL+K+ YE+LF W+V R+N+
Sbjct: 410 RLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNR 469
Query: 447 QLDTKLPRQ--HFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 504
LD + PRQ F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++
Sbjct: 470 ALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQR 528
Query: 505 EGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKS 561
EGI WTF+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ Q G
Sbjct: 529 EGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGH 587
Query: 562 NNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHL 621
FQ+P+ ++ +A+ FS++HYAG VDY + WL KN DPLN+ V L +S++RL A +
Sbjct: 588 PKFQRPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
Query: 622 Y-------------ATFATADADS-----------------GKKKVA---------KKKG 642
+ +F + S G ++V+ + +
Sbjct: 646 WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRR 705
Query: 643 SSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEG 702
F+TV L++E+L++LM+ L T+P FVRCI+PN K G +E LVL QLRCNGVLEG
Sbjct: 706 GMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEG 765
Query: 703 IRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHT 762
IRICR+GFPNRIL+ +F+QRY +L +AIP+G F+D K+ACEK++ ++++D Y+ G +
Sbjct: 766 IRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQS 824
Query: 763 KVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSF 822
K+FF+AG+L LEE RD ++ +I QA RG+L R FQK Q++ ++ +Q N ++
Sbjct: 825 KIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAY 884
Query: 823 MNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLV 882
+ ++HW W +LF K+KPLL+ ++ + +E QK ++ +S + EL+ ++ L
Sbjct: 885 LKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLE 944
Query: 883 QEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKR 942
+E+ L Q++AE+E +AEE +L K +LE + E+ R +EEE + ++ +K+
Sbjct: 945 EERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKK 1004
Query: 943 KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQE 1002
+L+ EL+ ++ E K++ EK TE K+K E+L L++ +KL++E+K L++
Sbjct: 1005 RLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLED 1064
Query: 1003 AHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKL 1062
+ EE+KV SLNK + K E + D+E L +E+K R +LE+ KR+L+G+
Sbjct: 1065 RLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSE 1124
Query: 1063 AQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEE 1122
QE +++ + ++L +L +K+ E ++ EDE Q K ++E QA + E +E+
Sbjct: 1125 LQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQED 1184
Query: 1123 IEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEA 1182
+E+ER R K EKQR D ELE L LE+ T+ Q EL KRE E +L++ LEE
Sbjct: 1185 LESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEE 1244
Query: 1183 TLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKS 1242
T HEA V LR++H ++ EL EQ++ +R K EK + + E+ +L + + S+ +
Sbjct: 1245 TRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1304
Query: 1243 KANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQL 1302
+ E+ R LE QL E +G+ + +R+ +E + R Q E +S L E ES +L
Sbjct: 1305 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRL 1364
Query: 1303 SRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRAL 1362
S+ + Q + + L+EE +AK AL +++ + LREQ EEE + R L
Sbjct: 1365 SKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGREL 1424
Query: 1363 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRL 1422
A +++++WR + E +A E EEA+++ A+ + +++ LE+ ++RL
Sbjct: 1425 QTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
Query: 1423 QGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTEL 1482
Q E++D +D+E+ L + L+KKQR FD++LAE K + E E + E R
Sbjct: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
Query: 1483 FKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQ 1542
L A EE + E ++R+N+ L E+ L + GK++HELE++ + E D++
Sbjct: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
Query: 1543 LALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSAL 1602
+ E E L E LR+++ + +K++ +R + +DE E+ +R + + +
Sbjct: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
Query: 1603 DAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDAL 1662
D E + R A+ +KK+EG+L E++ Q++ A + E +K LR +Q Q+K+ +++
Sbjct: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
Query: 1663 RGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNT 1722
+E++ Q E+R L+AEV L+ L ++RAR+ A+Q+ + + V +
Sbjct: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
Query: 1723 SLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLER 1782
+++ K++LE L QL+ E+E+ ++ ++ +K + + EL E+ SA E
Sbjct: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843
Query: 1783 MKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLR 1842
++ LE+ +++L+ RL E + A K I LE+++ + E +LE E ++ S K +R
Sbjct: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903
Query: 1843 KYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQH 1902
+ E+R+KE+ Q EE+R+ +L+D ++K ++VK KRQ EEA+E+A+ R+ Q
Sbjct: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963
Query: 1903 ELEEAEERADIAESQVNKLRAKTR 1926
ELE+ E A+ +V LR + R
Sbjct: 1964 ELEDVTESAESMNREVTTLRNRLR 1987
Score = 124 bits (311), Expect = 9e-28
Identities = 163/721 (22%), Positives = 313/721 (43%), Gaps = 81/721 (11%)
Query: 1269 RSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKN 1328
+ L ++T Q LQ A EL + V +L + + + QLEEE +
Sbjct: 900 KPLLQVTRQDEVLQARAQELQK--------VQELQQQSAREVGELQGRVAQLEEE---RA 948
Query: 1329 ALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELE 1388
LA L++ C E K EL+ +S+ + V + + + +++
Sbjct: 949 RLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEE--------ECSRQMQ 1000
Query: 1389 EAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQR 1448
KK+L Q +Q+ E +EA L+ K + +++ D+ + L K+++
Sbjct: 1001 TEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERK 1060
Query: 1449 NFDKVLAEWKTKCEESQAELEA----SLKESRSLSTELFKLKNAYEEALDQLETVKRENK 1504
+ LAE+ ++ E + ++++ LK +++ +L+ E+ +LE +KR
Sbjct: 1061 LLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE-EKGRQELEKLKRR-- 1117
Query: 1505 NLEQEIADLTEQIAENGKTIHEL--EKSRKQIELEKADIQLALEEAEAALEHEEAKILR- 1561
L+ E ++L EQ+ E + EL + RK+ EL+ A LA E E + K LR
Sbjct: 1118 -LDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAA---LARAEDEGGARAQLLKSLRE 1173
Query: 1562 IQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEG 1621
Q L + + +++ + + + E+ +R+ +E ++ L+ + S N L+ K E
Sbjct: 1174 AQAALAEAQEDLESERVARTKA-EKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQ 1232
Query: 1622 DLNEIEIQLSHANRQAAETLKHLRSVQGQ-LKDTQLHLDDALRGQEDLKEQLAIVERRAN 1680
++ E++ L R ++ LR GQ L + L+ A RG+ ++ +E +
Sbjct: 1233 EVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVS 1292
Query: 1681 LLQAEVEELRATLEQTERARKLAEQEL--------------LDSNERVQLLHTQNTSLIH 1726
L+AE+ L+ ++ E+ R+ E +L ++ E++Q + ++
Sbjct: 1293 ELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSG 1352
Query: 1727 TKKKLETDLMQLQSEVEDASRDARNAEE------KAKKAI--------TDAAMMAEELKK 1772
+ E+ ++L E+ +A+E +AK A+ +AA + E+L++
Sbjct: 1353 ALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEE 1412
Query: 1773 EQDTSAHLERMKKNLEQTVKDLQH--RLDEAEQLALKGGKKQIQKLETRIRELEFELEGE 1830
E +A ER + L+ L R E E AL+ G++ ++ L L +
Sbjct: 1413 E---AAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEK 1469
Query: 1831 QKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRL---QDLVDKLQVKVKSYKRQAEEAD 1887
+ +G R+ ++ + + T E+ R+ V L Q D+L + K+ +A E
Sbjct: 1470 TETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEER 1529
Query: 1888 EQANAHLTKFRKAQ-----HELEEAEERADIAESQVNKLRAKTRDFTSSR----MVVHES 1938
E+A A + R+A+ LEE +E + E Q LRA+ SS+ VHE
Sbjct: 1530 ERAEAE-GREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHEL 1588
Query: 1939 E 1939
E
Sbjct: 1589 E 1589
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 606 bits (1562), Expect = e-173
Identities = 428/1364 (31%), Positives = 682/1364 (50%), Gaps = 114/1364 (8%)
Query: 72 VKPEDVYAM-NPPKFDRIEDMAMLTHLNEPAVLYNLKDRYT-SWMIYTYSGLFCVTVNPY 129
V PE + + NP D+ L++L+EPAVL+NL+ R+ S +IYTYSG+ V +NPY
Sbjct: 52 VNPESLPPLRNPDILVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPY 111
Query: 130 KWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNT 189
K LP+Y ++ Y G+ + PHIF++++ AY+ M + NQSI+++GESGAGKTV+
Sbjct: 112 KQLPIYGDAIIHAYSGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSA 171
Query: 190 KRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFI 249
+ ++YFAT++ +G A +ED+++++NP+ EA GNAKT RNDNSSRFGK+
Sbjct: 172 RYAMRYFATVSKSGSNAH---------VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYT 222
Query: 250 RIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSN-KKPELIELLLITTNP 308
I F ++ A++ TYLLEKSRV FQ + ER+YHIFYQ+ ++ ++ E L L +
Sbjct: 223 EISFDEQNQIIGANMSTYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEE 282
Query: 309 YDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQK 368
++Y + G ++ ++D E++ T +LGF + + ++K+ A++H GN++
Sbjct: 283 FNYTRMG-GNTVIEGVNDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAV 341
Query: 369 QREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNAL 428
E + + L+GL S + + LC ++ +E V K T Q +A +AL
Sbjct: 342 GNERSSVSEDDSHLKVFCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDAL 401
Query: 429 SKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQ 488
+K +Y LF ++V RINQ L + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ
Sbjct: 402 AKKIYAHLFDFIVERINQALQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQ 461
Query: 489 FFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTS 548
FN H+F LEQEEY KE I WT IDF D I+LIE MGI +L+EEC+ P TD +
Sbjct: 462 QFNMHVFKLEQEEYMKEDIPWTLIDF-YDNQPVIDLIEAKMGILELLDEECLLPHGTDEN 520
Query: 549 FKNKLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVG 608
+ KLY+ + ++ F+KP++ + F + H+A V+Y G+LEKN+D + + +V
Sbjct: 521 WLQKLYNNFVNRNPLFEKPRM----SNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVE 576
Query: 609 LYQKSSNRLLAHLYATFATADADSGK-------KKVAKKKGSSFQ-TVSALFRENLNKLM 660
+ + S L A+ + T + G K+V K F+ TV + FR +L LM
Sbjct: 577 ILRASKFHLCANFFQENPTPPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLM 636
Query: 661 SNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFK 720
L T PH+VRCI PN+ K P + ++ QLR GVLE IRI + +P+R Y +F
Sbjct: 637 ETLNATTPHYVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFY 696
Query: 721 QRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDD 780
RY +L E F D K+ C+ +L + D QY+FG TK+FF+AG + LE++R D
Sbjct: 697 SRYGILMTK--QELSFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLD 754
Query: 781 RLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVK--------HWPWMK 832
+L + Q RG+L R +K ++ R + IQ R V+ W
Sbjct: 755 KLRQSCVMVQKHMRGWLQR---KKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAA 811
Query: 833 LFFKIK---PLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQ 889
+ + L++S MAT+ Q RK LEE ++Q+
Sbjct: 812 IIIQKHCRGYLVRSLYQLIRMATI--TMQAYSRGFLARRRYRKMLEEHKAVILQKYARAW 869
Query: 890 LQVQAESENLLDAEERCDQLIK--AKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 947
L A R + + QL +++ + ++ ED+ + N L K L
Sbjct: 870 L-----------ARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAAL 918
Query: 948 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQA 1007
+ + I LE L K + E K K + ++E +AKL + L+ +Q
Sbjct: 919 RAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRD---AVEEKLAKLQKHNSELETQKEQI 975
Query: 1008 LDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESI 1067
LQ + +++ K K++ + L +++E++ R+ LE++ +LK
Sbjct: 976 QLKLQEKTEEL------KEKMDNLTKQLFDDVQKEERQRMLLEKS-----FELKTQ---- 1020
Query: 1068 LDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQAR---IEELEEEIE 1124
D E Q L E +K E QLQ VE E + ++ L + I E E+EIE
Sbjct: 1021 -DYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIE 1079
Query: 1125 AERATRAKTEK----QRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLE 1180
+A + EK Q+ + ++ E++++L E+ + + L+ + DLE
Sbjct: 1080 LLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVE----------DLE 1129
Query: 1181 EATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVS 1240
E A K A V E + Q K EKE ++ LS + +
Sbjct: 1130 HLNEDGELWFAYEGLKKATRVLE-----SHFQSQKDCYEKEIEALNFKVVHLSQEINHLQ 1184
Query: 1241 KSKANLEKICRTLEDQLSEARGKN---EEIQRSLSELTTQKSRLQTEAGELSRQLEEK-E 1296
K I ++ +++ +N + ++ +SEL QK L+ E + +++ K E
Sbjct: 1185 KLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLE 1244
Query: 1297 SIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKA 1356
+ +QL RS++ Q + L+ Q E K K L +Q + D L++Q+E E E K
Sbjct: 1245 ELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKC 1304
Query: 1357 ELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQD 1400
++ S+ E + EE + K ++ ++LQD
Sbjct: 1305 NFRQEASRLTLE------------NRDLEEELDMKDRVIKKLQD 1336
Score = 90.9 bits (224), Expect = 1e-17
Identities = 140/643 (21%), Positives = 275/643 (42%), Gaps = 129/643 (20%)
Query: 781 RLAKLITRT-QAVCRGFLMRVEFQKMVQRRESIFCIQY-----NIRSFMNVKHWPW-MKL 833
+L ++ T T QA RGFL R ++KM++ +++ +Y R F +++ + ++L
Sbjct: 828 QLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQL 887
Query: 834 FFKIKPLLKSAETEKE-----------MATMK----EEFQKTKDELAKSEAKRKELEEKL 878
++++ L K E + + +A ++ E+ QK + EL K+ R+ EEK
Sbjct: 888 TYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEK- 946
Query: 879 VTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELT 938
+ A E L ++ +L K Q++ K++E TE
Sbjct: 947 ---------GKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEEL----------- 986
Query: 939 AKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKK 998
K K+++ +L D+ E +EK + E K ++ +++ L E I L EK
Sbjct: 987 --KEKMDNLTKQLFDDVQKEERQRMLLEK---SFELKTQDYEKQIQSLKEEIKALKDEKM 1041
Query: 999 ALQ---EAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRK 1055
LQ E D L+AE +++ KT S+ E+++E L++ ++D+E++ +
Sbjct: 1042 QLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQ-------KIDVEKHVQS 1094
Query: 1056 LEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQAR 1115
+ +++ E + + L+ D E + + VED L+ + EL
Sbjct: 1095 QKREMR---------EKMSEITKQLLESYDIEDVRSRLSVED-----LEHLNEDGELWFA 1140
Query: 1116 IEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKL 1175
E L+ +A R + + Q+ Y +E+E L+ + V E+N + + +
Sbjct: 1141 YEGLK---KATRVLESHFQSQKDCYEKEIEALNFK------VVHLSQEINHLQ--KLFRE 1189
Query: 1176 RRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSS 1235
D+ E +++HE V L ++ + + +QI L++ KQ LE +
Sbjct: 1190 ENDINE-SIRHE--VTRLTSENM-MIPDFKQQISELEKQKQDLEIRLN------------ 1233
Query: 1236 MESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEK 1295
E K K LE++ + ++ RS E TQ+ L+ + E+ +EK
Sbjct: 1234 -EQAEKMKGKLEEL--------------SNQLHRSQEEEGTQRKALEAQ-NEI--HTKEK 1275
Query: 1296 ESIVSQLSRSKQAFTQQTEELKRQLEEENKAK-------NALAHALQSSRHDCDLLREQY 1348
E ++ ++ ++A ++ LK+Q E E++ K + L + + D+
Sbjct: 1276 EKLIDKIQEMQEA----SDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVI 1331
Query: 1349 EEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAK 1391
++ Q+ L + + KAN + K +Q E +EAK
Sbjct: 1332 KKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKRE-DEAK 1373
Score = 88.6 bits (218), Expect = 5e-17
Identities = 111/534 (20%), Positives = 236/534 (44%), Gaps = 63/534 (11%)
Query: 1310 TQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEV 1369
T + + L+++LE++NK + L L S L E+ Q+ +AEL++A
Sbjct: 888 TYRVQRLQKKLEDQNKENHGLVEKLTSL---AALRAGDVEKIQKLEAELEKA-------- 936
Query: 1370 AQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCAS-LEKTKQRLQGEVED 1428
A R YE + + +EE KL + + E Q E + K E+ K+++ +
Sbjct: 937 ATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQ 996
Query: 1429 LMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNA 1488
L DV++ L+K ++ K ++ + ++++ +E ++L E +L++
Sbjct: 997 LFDDVQKEERQRMLLEKS----------FELKTQDYEKQIQSLKEEIKALKDEKMQLQHL 1046
Query: 1489 YEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEA 1548
E E V + L+ E+A L++Q+ KTI E EK + ++ +K D++ ++
Sbjct: 1047 VEG-----EHVTSDG--LKAEVARLSKQV----KTISEFEKEIELLQAQKIDVEKHVQSQ 1095
Query: 1549 EAALEHEEAKILRIQLE---LTQVKSEI---DRKIAEKDEEIEQLKRNYQRTVETMQSAL 1602
+ + + ++I + LE + V+S + D + +D E+ ++ ++S
Sbjct: 1096 KREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHF 1155
Query: 1603 DAE---VRSRNEAIRLKK-KMEGDLNEIEIQLSHANRQAAETLKH----LRSVQGQLKDT 1654
++ EA+ K + ++N ++ +L E+++H L S + D
Sbjct: 1156 QSQKDCYEKEIEALNFKVVHLSQEINHLQ-KLFREENDINESIRHEVTRLTSENMMIPDF 1214
Query: 1655 QLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERV 1714
+ + + + ++DL+ +L +A ++ ++EEL L +++ + L NE
Sbjct: 1215 KQQISELEKQKQDLEIRL---NEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNE-- 1269
Query: 1715 QLLHT-QNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKE 1773
+HT + LI ++++ L+ + E S N ++A + + + EEL +
Sbjct: 1270 --IHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMK 1327
Query: 1774 QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFEL 1827
+R+ K L+ VK L + +A + G K+ + RE E +L
Sbjct: 1328 -------DRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDEAKL 1374
Score = 84.7 bits (208), Expect = 8e-16
Identities = 118/511 (23%), Positives = 226/511 (44%), Gaps = 60/511 (11%)
Query: 1176 RRDLEEATLQHEAMV------AALRKKHADSVAELGEQID---NLQRVKQKLEKEKSEFK 1226
RR + +H+A++ A L ++ S+ I +QR+++KLE + E
Sbjct: 847 RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENH 906
Query: 1227 LEIDDLSS-------SMESVSKSKANLEKIC---RTLEDQLSEARGKNEE----IQRSLS 1272
++ L+S +E + K +A LEK R E++ R EE +Q+ S
Sbjct: 907 GLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNS 966
Query: 1273 ELTTQKSRLQTEAGELSRQLEEK-ESIVSQLSRSKQ-----------AFTQQTEELKRQL 1320
EL TQK ++Q + E + +L+EK +++ QL Q +F +T++ ++Q+
Sbjct: 967 ELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQI 1026
Query: 1321 EEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 1380
+ + AL +H L+ ++ KAE+ R LSK ++++ + E
Sbjct: 1027 QSLKEEIKALKDEKMQLQH---LVEGEHVTSDGLKAEVAR-LSKQVKTISEFEKEIE--- 1079
Query: 1381 IQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLA 1440
+ + ++++ K +Q+ + E+ E S + R + VEDL + L
Sbjct: 1080 LLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDL-EHLNEDGELW 1138
Query: 1441 AALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVK 1500
A + ++ + + ++++ + + E+EA + LS E+ L+ + E D E+++
Sbjct: 1139 FAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIR 1198
Query: 1501 RENKNLEQE---IADLTEQIAENGKTIHELE-KSRKQIELEKADIQLALEEAEAALEHE- 1555
E L E I D +QI+E K +LE + +Q E K ++ + + E E
Sbjct: 1199 HEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEG 1258
Query: 1556 -EAKILRIQLEL-TQVKSEIDRKIAEKDEEIEQLKRNYQRTVETM------QSALDAEVR 1607
+ K L Q E+ T+ K ++ KI E E + LK+ ++ E S L E R
Sbjct: 1259 TQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENR 1318
Query: 1608 SRNEAIRLK----KKMEGDLNEIEIQLSHAN 1634
E + +K KK++ + + + AN
Sbjct: 1319 DLEEELDMKDRVIKKLQDQVKTLSKTIGKAN 1349
Score = 76.3 bits (186), Expect = 3e-13
Identities = 101/517 (19%), Positives = 218/517 (42%), Gaps = 51/517 (9%)
Query: 1447 QRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAY--EEALDQLETVKRENK 1504
+R + K+L E K + A + + +S+ + ++ Y + +LE +EN
Sbjct: 847 RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENH 906
Query: 1505 NLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQL 1564
L +++ L A + + I +LE ++ + + + + A+E + AK+ +
Sbjct: 907 GLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNS 966
Query: 1565 ELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLN 1624
EL K +I K+ EK EE+++ N + + D + + + L+K E
Sbjct: 967 ELETQKEQIQLKLQEKTEELKEKMDNLTKQL------FDDVQKEERQRMLLEKSFELKTQ 1020
Query: 1625 EIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQ----EDLKEQLAIVERRAN 1680
+ E Q ++ L+ LKD ++ L + G+ + LK ++A + ++
Sbjct: 1021 DYEKQ-----------IQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVK 1069
Query: 1681 LL---QAEVEELRATLEQTERARKLAEQELLDSNERV--QLLHTQNTSLIHTKKKLETDL 1735
+ + E+E L+A E+ + ++E+ + + QLL + + + ++ +E DL
Sbjct: 1070 TISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVE-DL 1128
Query: 1736 MQLQSE---------VEDASRDARNAEEKAK----KAITDAAMMAEELKKEQDTSAHLER 1782
L + ++ A+R + + K K I L +E + L R
Sbjct: 1129 EHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFR 1188
Query: 1783 MKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLR 1842
+ ++ ++++ RL +E + + K+QI +LE + ++LE L + +K ++ L
Sbjct: 1189 EENDINESIRHEVTRL-TSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELS 1247
Query: 1843 KYERRVKE--------LTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHL 1894
R +E L Q+E K +L D + ++Q K+Q E E
Sbjct: 1248 NQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFR 1307
Query: 1895 TKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSS 1931
+ + E + EE D+ + + KL+ + + + +
Sbjct: 1308 QEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKT 1344
Score = 62.0 bits (149), Expect = 5e-09
Identities = 76/386 (19%), Positives = 161/386 (41%), Gaps = 65/386 (16%)
Query: 841 LKSAETEKEMATMKEEFQKTKDE------------------------LAKSEAKRKELEE 876
LK+ + EK++ ++KEE + KDE L+K E E+
Sbjct: 1017 LKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEK 1076
Query: 877 KLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTER--AEDEEEIN 934
++ L +K D++ VQ++ + E+ ++ K + I++V R ED E +N
Sbjct: 1077 EIELLQAQKIDVEKHVQSQKREM---REKMSEITKQLLE-SYDIEDVRSRLSVEDLEHLN 1132
Query: 935 AE---------LTAKKRKLEDECSELK----KDIDDLELTLAKVEKEKHATENKVKNLTE 981
+ L R LE K K+I+ L + + +E + + + +
Sbjct: 1133 EDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREEND 1192
Query: 982 ELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQ 1041
+ + +LT E + + QQ + + ++D LN+ K++ ++E+L + L +
Sbjct: 1193 INESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHR 1252
Query: 1042 EKKLRVDLERNKRKLEGDLKLAQ-ESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQT 1100
++ +R + + ++ + E ++D + Q+ + LKK + E E
Sbjct: 1253 SQE-EEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKK----------QFETESE 1301
Query: 1101 LGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTST 1160
+ F+++ L +LEEE++ + K + Q ++ LS+ + +A V S+
Sbjct: 1302 VKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQ-------VKTLSKTIGKANDVHSS 1354
Query: 1161 QIELNKKREAEFLKLRRDLEEATLQH 1186
K L+ +R+ E +Q+
Sbjct: 1355 S---GPKEYLGMLQYKREDEAKLIQN 1377
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 603 bits (1555), Expect = e-172
Identities = 438/1442 (30%), Positives = 730/1442 (50%), Gaps = 129/1442 (8%)
Query: 81 NPPKFDRIEDMAMLTHLNEPAVLYNLKDRYT-SWMIYTYSGLFCVTVNPYKWLPVYNPEV 139
NP D+ L++L+EPAVL+NL+ R+ S +IYTY G+ V +NPY+ LP+Y ++
Sbjct: 64 NPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDI 123
Query: 140 VEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATI 199
+ Y G+ + PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFAT+
Sbjct: 124 INAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATV 183
Query: 200 AATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKL 259
+ S + +E++++++NP++E+ GNAKT RNDNSSRFGK+I I F ++
Sbjct: 184 SG---------SASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRI 234
Query: 260 ASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKK-PELIELLLITTNPYDYPFISQGE 318
A++ TYLLEKSRV FQ + ER+YHIFYQ+ ++ K PE L L + ++Y G
Sbjct: 235 IGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTK-QGGS 293
Query: 319 ILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDG 378
++ +DDA+E+ T A +LG + + G++++ ++H GN+ F + + P
Sbjct: 294 PVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPK 353
Query: 379 TEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFL 438
E LMG++ ++ LC ++ E K + Q +A +AL+K +Y KLF
Sbjct: 354 HEPLCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFN 413
Query: 439 WMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLE 498
W+V +NQ L + + + FIGVLDI GFE FE NS EQ CIN+ NEKLQQ FN H+F LE
Sbjct: 414 WIVDNVNQALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLE 473
Query: 499 QEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHL 558
QEEY KE I WT IDF D CI LIE +GI +L+EEC PK TD ++ KLY+ HL
Sbjct: 474 QEEYMKEQIPWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHL 532
Query: 559 GKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLL 618
K F+KP++ + F + H+A V+Y G+LEKNKD + E + + + S ++L
Sbjct: 533 NKCALFEKPRL----SNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKML 588
Query: 619 AHLY-----ATFATADADSGKKKVAK-----KKGSSFQ-------TVSALFRENLNKLMS 661
L+ A T+ SG+ + + KG Q TV FR +L+ LM
Sbjct: 589 PELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLME 648
Query: 662 NLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQ 721
L T PH+VRCI PN+ K P + + QLR GVLE IRI GFP+R Y +F
Sbjct: 649 TLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFS 708
Query: 722 RYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDR 781
RYRVL + D K+ C+ +L + +D +Y+FG TK+FF+AG + LE++R D+
Sbjct: 709 RYRVLMKQ---KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADK 765
Query: 782 LAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFM---------NVKHWPWMK 832
L R Q RG+L+R ++ +M R++ +Q +R + K ++
Sbjct: 766 LRAACIRIQKTIRGWLLRKKYLRM---RKAAITMQRYVRGYQARCYAKFLRRTKAATIIQ 822
Query: 833 LFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQE--KNDLQL 890
++++ + + + + + + + + LA++ RK L E ++Q+ + L
Sbjct: 823 KYWRMYVVRRRYKIRRAATIVLQSY--LRGFLARNR-YRKILREHKAVIIQKRVRGWLAR 879
Query: 891 QVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 950
S + + + C + + AK +L+ K+K E ++++ + K +L+ + E
Sbjct: 880 THYKRSMHAIIYLQCCFRRMMAKRELK-KLKIEARSVERYKKLHIGMENKIMQLQRKVDE 938
Query: 951 LKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDD 1010
KD L L +E ++ K+++ E L +E T +LQE + D
Sbjct: 939 QNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKD 998
Query: 1011 LQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDL 1070
L+ + + + + +Q+ E L S+L++E L L++ K L + +
Sbjct: 999 LEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTL---LKQEKEALNHRI---------V 1046
Query: 1071 ENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEI------- 1123
+ K+ + KK E QL+ + DE+ + L+ R ++L+EE+
Sbjct: 1047 QQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVP 1106
Query: 1124 -EAERATRAKTEKQRSDY-----ARELEELSERLEEAGGVTSTQIELN-------KKREA 1170
+ T + S+Y E+E++ R EE + ++ L+ +KR
Sbjct: 1107 KPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEP---SEKKVPLDMSLFLKLQKRVT 1163
Query: 1171 EFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEID 1230
E + ++ +++ + E V + K + G +++ +Q+LE E + K E++
Sbjct: 1164 ELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELN 1223
Query: 1231 DLSSSM--ESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGEL 1288
+L ++ +S + A R L +QL+ +EE+ E+ +S+L
Sbjct: 1224 ELRKALSEKSAPEVTAPGAPAYRVLMEQLTSV---SEELDVRKEEVLILRSQL------- 1273
Query: 1289 SRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAH-ALQSSRHDCDLLREQ 1347
+ +KE+I Q K T T L+ + ++K + A A+ L+ + L +
Sbjct: 1274 ---VSQKEAI--QPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSAL--DY 1326
Query: 1348 YEEEQEGKAEL-QRALSKAN----SEVAQWRTKYETDAIQRTEELEEAKKK-------LA 1395
+E ++G+ L L +AN S++ + +E +A E++ K++ LA
Sbjct: 1327 HELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLA 1386
Query: 1396 QRLQ-DSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVL 1454
Q LQ E ++E ASL+ RL E DLM +E+ + L K+ + F K +
Sbjct: 1387 QNLQLPPEARIE------ASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKI 1440
Query: 1455 AE 1456
E
Sbjct: 1441 GE 1442
Score = 78.2 bits (191), Expect = 7e-14
Identities = 137/624 (21%), Positives = 264/624 (42%), Gaps = 84/624 (13%)
Query: 1208 IDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEI 1267
++ +++ +E + + + ++D+ + + + + NLE I + ++L R E +
Sbjct: 915 VERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKL---RSDLERL 971
Query: 1268 QRSLSELTTQKSR---LQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEEN 1324
Q S E R LQ E +L + LE+ S + + Q+TE+L L+EEN
Sbjct: 972 QLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEEN 1031
Query: 1325 KAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRT 1384
LL+++ E N + Q + K T+ +++
Sbjct: 1032 -----------------TLLKQEKE--------------ALNHRIVQ-QAKEMTETMEK- 1058
Query: 1385 EELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDV-----ERANSL 1439
+L E K+L L D + + + + + LE+ L+ E+ LMV V +R +S
Sbjct: 1059 -KLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEM-TLMVHVPKPGHKRTDST 1116
Query: 1440 AAALDKKQRNFDKVLAEWK------TKCEESQAELEASL-KESRSLSTELFKLKNAYEEA 1492
++ ++ + F +AE + + E + L+ SL + + TEL + K ++
Sbjct: 1117 HSS-NESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDE 1175
Query: 1493 LDQLETVKRENKNLEQEIADLT-EQIAENGKTIHELEKSRKQIELEKADIQLALEEAEA- 1550
LD+ E +K E+E + ++ ELE K+++ E +++ AL E A
Sbjct: 1176 LDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAP 1235
Query: 1551 ALEHEEAKILRIQLE-LTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSR 1609
+ A R+ +E LT V E+D + EE+ L+ E +Q D +
Sbjct: 1236 EVTAPGAPAYRVLMEQLTSVSEELD----VRKEEVLILRSQLVSQKEAIQPKDDKNTMTD 1291
Query: 1610 NEAIR---LKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQE 1666
+ + K K +G++ + I L NR +A L G+L L A R E
Sbjct: 1292 STILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNE-DGELWLVYEGLKQANRLLE 1350
Query: 1667 -DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQEL-LDSNERVQL-------- 1716
L+ Q E A L+ E++ L+ E+ R ++L Q L L R++
Sbjct: 1351 SQLQSQKRSHENEAEALRGEIQSLK---EENNRQQQLLAQNLQLPPEARIEASLQHEITR 1407
Query: 1717 LHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEEL------ 1770
L +N L+ +K + + +L+ +++ ++ E + I+ ++ E +
Sbjct: 1408 LTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIP 1467
Query: 1771 KKEQDTSAHLERMKKNLEQTVKDL 1794
+KE+D LE K++ ++ VK+L
Sbjct: 1468 RKEKDFQGMLEYKKEDEQKLVKNL 1491
Score = 73.9 bits (180), Expect = 1e-12
Identities = 123/552 (22%), Positives = 243/552 (44%), Gaps = 58/552 (10%)
Query: 1017 KVNSLNKTKSKLEQQVEDLESSLEQE-KKLRVDLERNKRKLEGDLKLAQESILDLENDKQ 1075
KV+ NK L +++ +LE E +KLR DLER + E + K+A +L L+ +
Sbjct: 935 KVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLS-EEEAKVATGRVLSLQEEIA 993
Query: 1076 QLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEK 1135
+L +KD E + + K +E + +E + + L+EE T K EK
Sbjct: 994 KL-----RKDLEQTRSEKKCIEEHA-----DRYKQETEQLVSNLKEE-----NTLLKQEK 1038
Query: 1136 QRSDY--ARELEELSERLEEAGGVTSTQIELNKKREA--------EFLKLRRDLEEATLQ 1185
+ ++ ++ +E++E +E+ + Q+EL+ E EF +L ++ +
Sbjct: 1039 EALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEE 1098
Query: 1186 HEAMVAALRKKH--ADSVAELGE-------QIDNLQRVKQKLEKEKSEFKLEIDDLSSSM 1236
MV + H DS E +I ++ + + E E SE K+ +D S
Sbjct: 1099 MTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTE-EPSEKKVPLD--MSLF 1155
Query: 1237 ESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKE 1296
+ K LE+ + ++D+L K E++ RS ++ ++ R Q EL + +++
Sbjct: 1156 LKLQKRVTELEQEKQVMQDELDR---KEEQVLRSKAK---EEERPQIRGAELEYESLKRQ 1209
Query: 1297 SIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKA 1356
+ S+ + K + EL++ L E++ A A + R + L EE K
Sbjct: 1210 ELESENKKLKN----ELNELRKALSEKS-APEVTAPGAPAYRVLMEQLTSVSEELDVRKE 1264
Query: 1357 ELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNA-KCASL 1415
E+ S+ S+ + K + + + + L E +K+ + + ++ + + ++L
Sbjct: 1265 EVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSAL 1324
Query: 1416 EKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKES 1475
+ + GE+ + +++AN L + + Q+ + AE E Q+ E + ++
Sbjct: 1325 DYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAE--ALRGEIQSLKEENNRQQ 1382
Query: 1476 RSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIE 1535
+ L+ L A EA Q E + N+NL DL EQ+ + KT+ +L+K K
Sbjct: 1383 QLLAQNLQLPPEARIEASLQHEITRLTNENL-----DLMEQLEKQDKTVRKLKKQLKVFA 1437
Query: 1536 LEKADIQLALEE 1547
+ ++++ E
Sbjct: 1438 KKIGELEVGQME 1449
Score = 63.5 bits (153), Expect = 2e-09
Identities = 113/501 (22%), Positives = 221/501 (44%), Gaps = 94/501 (18%)
Query: 1464 SQAELEASLKESRSLSTELFKLKNAYEEALDQLET-VKRENKNLEQEIADLTEQIAENGK 1522
++ EL+ E+RS+ KL E + QL+ V +NK+ + + LT N +
Sbjct: 901 AKRELKKLKIEARSVE-RYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLT-----NLE 954
Query: 1523 TIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDE 1582
I+ E + + +LE+ +QL+ EEA+ A ++L +Q E+ +++ ++++ +EK +
Sbjct: 955 GIYNSETEKLRSDLER--LQLSEEEAKVAT----GRVLSLQEEIAKLRKDLEQTRSEK-K 1007
Query: 1583 EIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLK 1642
IE+ Y++ E + S L + E LK++ E LN +Q + ++ ET++
Sbjct: 1008 CIEEHADRYKQETEQLVSNL------KEENTLLKQEKEA-LNHRIVQQA---KEMTETME 1057
Query: 1643 HLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKL 1702
+ + + K +L L+D ++L + + +E R + L+ EE+ + + K
Sbjct: 1058 --KKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLK---EEMTLMVHVPKPGHK- 1111
Query: 1703 AEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITD 1762
T H+ + E +E+ED +R E KK D
Sbjct: 1112 ------------------RTDSTHSSNESEYIFSSEIAEMEDIP--SRTEEPSEKKVPLD 1151
Query: 1763 AAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRE 1822
++ + L++ LEQ + +Q LD E+ L+ K+ ++ + R E
Sbjct: 1152 MSLFLK-----------LQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAE 1200
Query: 1823 LEF------ELEGEQKKNTESVKGLRK-----------------YERRVKELTYQSEEDR 1859
LE+ ELE E KK + LRK Y +++LT SEE
Sbjct: 1201 LEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEE-- 1258
Query: 1860 KNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVN 1919
+V + + L+ L+ ++ S K + D++ +T ++++ +++ +IA++ +
Sbjct: 1259 LDVRKEEVLI--LRSQLVSQKEAIQPKDDKNT--MTDSTILLEDVQKMKDKGEIAQAYIG 1314
Query: 1920 KLRAKTRDFTSSRMVVHESEE 1940
L+ R SS + HE E
Sbjct: 1315 -LKETNR---SSALDYHELNE 1331
Score = 53.1 bits (126), Expect = 3e-06
Identities = 75/335 (22%), Positives = 141/335 (42%), Gaps = 61/335 (18%)
Query: 831 MKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAK------------------RK 872
M LF K++ + E EK++ M++E + ++++ +S+AK R+
Sbjct: 1152 MSLFLKLQKRVTELEQEKQV--MQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQ 1209
Query: 873 ELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEE 932
ELE + L E N+L+ + +S + A + + QL + +E+ R E+
Sbjct: 1210 ELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLME-QLTSVSEELDVRKEEVLI 1268
Query: 933 INAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAK 992
+ ++L ++K ++ + + K + D + L V+K K E + + GL ET
Sbjct: 1269 LRSQLVSQKEAIQPK--DDKNTMTDSTILLEDVQKMKDKGE-----IAQAYIGLKET--- 1318
Query: 993 LTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERN 1052
ALD + ED L L+Q LES L+ +K+ E
Sbjct: 1319 ----------NRSSALDYHELNED--GELWLVYEGLKQANRLLESQLQSQKRSH---ENE 1363
Query: 1053 KRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKEL 1112
L G+++ +E EN++QQ + ++ E + Q +I L
Sbjct: 1364 AEALRGEIQSLKE-----ENNRQQ----------QLLAQNLQLPPEARIEASLQHEITRL 1408
Query: 1113 QARIEELEEEIEAERATRAKTEKQRSDYARELEEL 1147
+L E++E + T K +KQ +A+++ EL
Sbjct: 1409 TNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGEL 1443
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 599 bits (1545), Expect = e-171
Identities = 434/1429 (30%), Positives = 715/1429 (50%), Gaps = 130/1429 (9%)
Query: 81 NPPKFDRIEDMAMLTHLNEPAVLYNLKDRYT-SWMIYTYSGLFCVTVNPYKWLPVYNPEV 139
NP D+ L++L+EPAVL+NL+ R+ S +IYTY G+ V +NPY+ LP+Y ++
Sbjct: 64 NPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDI 123
Query: 140 VEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATI 199
+ Y G+ + PHIF++++ AY+ M D NQSI+++GESGAGKTV+ K ++YFAT+
Sbjct: 124 INAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATV 183
Query: 200 AATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKL 259
+ S + +E++++++NP++E+ GNAKT RNDNSSRFGK+I I F ++
Sbjct: 184 SG---------SASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRI 234
Query: 260 ASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKK-PELIELLLITTNPYDYPFISQGE 318
A++ TYLLEKSRV FQ + ER+YHIFYQ+ ++ K PE L L + ++Y G
Sbjct: 235 IGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTK-QGGS 293
Query: 319 ILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDG 378
++ +DDA+E+ T A +LG + + G++++ ++H GN+ F + + P
Sbjct: 294 PVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPK 353
Query: 379 TEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFL 438
E LMG++ ++ LC ++ E K + Q +A +AL+K +Y KLF
Sbjct: 354 HEPLCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFN 413
Query: 439 WMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLE 498
W+V +NQ L + + + FIGVLDI GFE FE NS EQ CIN+ NEKLQQ FN H+F LE
Sbjct: 414 WIVDNVNQALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLE 473
Query: 499 QEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHL 558
QEEY KE I WT IDF D CI LIE +GI +L+EEC PK TD ++ KLY+ HL
Sbjct: 474 QEEYMKEQIPWTLIDF-YDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHL 532
Query: 559 GKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLL 618
K F+KP++ + F + H+A V+Y G+LEKNKD + E + + + S ++L
Sbjct: 533 NKCALFEKPRL----SNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKML 588
Query: 619 AHLY-----ATFATADADSGKKKVAKK-----KGSSFQ-------TVSALFRENLNKLMS 661
L+ A T+ SG+ + + KG Q TV FR +L+ LM
Sbjct: 589 PELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLME 648
Query: 662 NLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQ 721
L T PH+VRCI PN+ K P + + QLR GVLE IRI GFP+R Y +F
Sbjct: 649 TLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFS 708
Query: 722 RYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDR 781
RYRVL + D K+ C+ +L + +D +Y+FG TK+FF+AG + LE++R D+
Sbjct: 709 RYRVLMKQ---KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADK 765
Query: 782 LAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNIRSFM---------NVKHWPWMK 832
L R Q RG+L+R ++ +M R++ +Q +R + K ++
Sbjct: 766 LRAACIRIQKTIRGWLLRKKYLRM---RKAAITMQRYVRGYQARCYAKFLRRTKAATIIQ 822
Query: 833 LFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEK--NDLQL 890
++++ + + + + + + + + LA++ RK L E ++Q++ L
Sbjct: 823 KYWRMYVVRRRYKIRRAATIVLQSY--LRGFLARNRY-RKILREHKAVIIQKRVRGWLAR 879
Query: 891 QVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSE 950
S + + + C + + AK +L+ K+K E ++++ + K +L+ + E
Sbjct: 880 THYKRSMHAIIYLQCCFRRMMAKRELK-KLKIEARSVERYKKLHIGMENKIMQLQRKVDE 938
Query: 951 LKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDD 1010
KD L L +E ++ K+++ E L +E T +LQE + D
Sbjct: 939 QNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKD 998
Query: 1011 LQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDL 1070
L+ + + + + +Q+ E L S+L++E L L++ K L + +
Sbjct: 999 LEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTL---LKQEKEALNHRI---------V 1046
Query: 1071 ENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEI------- 1123
+ K+ + KK E QL+ + DE+ + L+ R ++L+EE+
Sbjct: 1047 QQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVP 1106
Query: 1124 -EAERATRAKTEKQRSDY-----ARELEELSERLEEAGGVTSTQIELN-------KKREA 1170
+ T + S+Y E+E++ R EE + ++ L+ +KR
Sbjct: 1107 KPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEP---SEKKVPLDMSLFLKLQKRVT 1163
Query: 1171 EFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEID 1230
E + ++ +++ + E V + K + G +++ +Q+LE E + K E++
Sbjct: 1164 ELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELN 1223
Query: 1231 DLSSSM--ESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGEL 1288
+L ++ +S + A R L +QL+ +EE+ E+ +S+L
Sbjct: 1224 ELRKALSEKSAPEVTAPGAPAYRVLMEQLTSV---SEELDVRKEEVLILRSQL------- 1273
Query: 1289 SRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQY 1348
+ +KE+I Q K T T L+ ++ K K +A A + LL Q
Sbjct: 1274 ---VSQKEAI--QPKDDKNTMTDSTILLED--VQKMKDKGEIAQAYIGLKETNRLLESQL 1326
Query: 1349 EEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ-DSEEQVEA 1407
+ ++ AL E+ + EE ++ LAQ LQ E ++E
Sbjct: 1327 QSQKRSHENEAEAL---RGEIQSLK-----------EENNRQQQLLAQNLQLPPEARIE- 1371
Query: 1408 VNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAE 1456
ASL+ RL E DLM +E+ + L K+ + F K + E
Sbjct: 1372 -----ASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1415
Score = 78.6 bits (192), Expect = 6e-14
Identities = 115/503 (22%), Positives = 232/503 (46%), Gaps = 71/503 (14%)
Query: 843 SAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDA 902
++ETEK + + E Q +++E + + L+E++ L + DL+ Q ++E + +
Sbjct: 958 NSETEKLRSDL-ERLQLSEEEAKVATGRVLSLQEEIAKL---RKDLE-QTRSEKKCI--- 1009
Query: 903 EERCDQLIKAKFQLEAKIKEV-TERAEDEEEINAELTAK--------KRKLEDECSELKK 953
EE D+ + QL + +KE T +++E +N + + ++KL +E +L+
Sbjct: 1010 EEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLEL 1069
Query: 954 DIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQA 1013
D++D L + +NL E S L+E L E + +
Sbjct: 1070 DLNDERL--------------RYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPG----HK 1111
Query: 1014 EEDKVNSLNKTK---SKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDL 1070
D +S N+++ S ++ED+ S E+ + +V L+ + LKL Q+ + +L
Sbjct: 1112 RTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLD-----MSLFLKL-QKRVTEL 1165
Query: 1071 ENDKQQLDERLKKKDFEYCQLQSKVEDE-QTLGLQFQ---KKIKELQARIEELEEEIEAE 1126
E +KQ + + L +K+ + + ++K E+ Q G + + K +EL++ ++L+ E+
Sbjct: 1166 EQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNEL 1225
Query: 1127 RATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQH 1186
R +A +EK + L E +TS EL+ ++E E L LR L Q
Sbjct: 1226 R--KALSEKSAPEVTAPGAPAYRVLMEQ--LTSVSEELDVRKE-EVLILRSQL---VSQK 1277
Query: 1187 EAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDD--LSSSMESVSKSKA 1244
EA+ K +++ + ++++Q++K K E ++ L+ + L S ++S +S
Sbjct: 1278 EAIQP---KDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHE 1334
Query: 1245 NLEKICRTLEDQLSEARGKNEEI----------QRSLSELTTQKSRLQTEAGELSRQLEE 1294
N + R L E + +++ R + L + +RL E +L QLE+
Sbjct: 1335 NEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEK 1394
Query: 1295 KESIVSQLSRSKQAFTQQTEELK 1317
++ V +L + + F ++ EL+
Sbjct: 1395 QDKTVRKLKKQLKVFAKKIGELE 1417
Score = 68.6 bits (166), Expect = 6e-11
Identities = 129/623 (20%), Positives = 255/623 (40%), Gaps = 109/623 (17%)
Query: 1208 IDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEI 1267
++ +++ +E + + + ++D+ + + + + NLE I + ++L R E +
Sbjct: 915 VERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKL---RSDLERL 971
Query: 1268 QRSLSELTTQKSR---LQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEEN 1324
Q S E R LQ E +L + LE+ S + + Q+TE+L L+EEN
Sbjct: 972 QLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEEN 1031
Query: 1325 KAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRT 1384
LL+++ E N + Q + K T+ +++
Sbjct: 1032 -----------------TLLKQEKE--------------ALNHRIVQ-QAKEMTETMEK- 1058
Query: 1385 EELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDV-----ERANSL 1439
+L E K+L L D + + + + + LE+ L+ E+ LMV V +R +S
Sbjct: 1059 -KLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEM-TLMVHVPKPGHKRTDST 1116
Query: 1440 AAALDKKQRNFDKVLAEWK------TKCEESQAELEASL-KESRSLSTELFKLKNAYEEA 1492
++ ++ + F +AE + + E + L+ SL + + TEL + K ++
Sbjct: 1117 HSS-NESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDE 1175
Query: 1493 LDQLETVKRENKNLEQEIADLT-EQIAENGKTIHELEKSRKQIELEKADIQLALEEAEA- 1550
LD+ E +K E+E + ++ ELE K+++ E +++ AL E A
Sbjct: 1176 LDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAP 1235
Query: 1551 ALEHEEAKILRIQLE-LTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSR 1609
+ A R+ +E LT V E+D + EE+ L+ E +Q D +
Sbjct: 1236 EVTAPGAPAYRVLMEQLTSVSEELD----VRKEEVLILRSQLVSQKEAIQPKDDKNTMTD 1291
Query: 1610 NEAIR---LKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQE 1666
+ + K K +G++ + I L NR +
Sbjct: 1292 STILLEDVQKMKDKGEIAQAYIGLKETNRLL---------------------------ES 1324
Query: 1667 DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQEL-LDSNERVQL--------L 1717
L+ Q E A L+ E++ L+ E+ R ++L Q L L R++ L
Sbjct: 1325 QLQSQKRSHENEAEALRGEIQSLK---EENNRQQQLLAQNLQLPPEARIEASLQHEITRL 1381
Query: 1718 HTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEEL------K 1771
+N L+ +K + + +L+ +++ ++ E + I+ ++ E + +
Sbjct: 1382 TNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPR 1441
Query: 1772 KEQDTSAHLERMKKNLEQTVKDL 1794
KE+D LE K++ ++ VK+L
Sbjct: 1442 KEKDFQGMLEYKKEDEQKLVKNL 1464
Score = 62.0 bits (149), Expect = 5e-09
Identities = 106/479 (22%), Positives = 212/479 (44%), Gaps = 90/479 (18%)
Query: 1464 SQAELEASLKESRSLSTELFKLKNAYEEALDQLET-VKRENKNLEQEIADLTEQIAENGK 1522
++ EL+ E+RS+ KL E + QL+ V +NK+ + + LT N +
Sbjct: 901 AKRELKKLKIEARSVE-RYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLT-----NLE 954
Query: 1523 TIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDE 1582
I+ E + + +LE+ +QL+ EEA+ A ++L +Q E+ +++ ++++ +EK +
Sbjct: 955 GIYNSETEKLRSDLER--LQLSEEEAKVAT----GRVLSLQEEIAKLRKDLEQTRSEK-K 1007
Query: 1583 EIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLK 1642
IE+ Y++ E + S L + E LK++ E LN +Q + ++ ET++
Sbjct: 1008 CIEEHADRYKQETEQLVSNL------KEENTLLKQEKEA-LNHRIVQQA---KEMTETME 1057
Query: 1643 HLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKL 1702
+ + + K +L L+D ++L + + +E R + L+ EE+ + + K
Sbjct: 1058 --KKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLK---EEMTLMVHVPKPGHK- 1111
Query: 1703 AEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITD 1762
T H+ + E +E+ED +R E KK D
Sbjct: 1112 ------------------RTDSTHSSNESEYIFSSEIAEMEDIP--SRTEEPSEKKVPLD 1151
Query: 1763 AAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRE 1822
++ + L++ LEQ + +Q LD E+ L+ K+ ++ + R E
Sbjct: 1152 MSLFLK-----------LQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAE 1200
Query: 1823 LEF------ELEGEQKKNTESVKGLRK-----------------YERRVKELTYQSEEDR 1859
LE+ ELE E KK + LRK Y +++LT SEE
Sbjct: 1201 LEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEE-- 1258
Query: 1860 KNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQV 1918
+V + + L+ L+ ++ S K + D++ +T ++++ +++ +IA++ +
Sbjct: 1259 LDVRKEEVLI--LRSQLVSQKEAIQPKDDKNT--MTDSTILLEDVQKMKDKGEIAQAYI 1313
Score = 56.2 bits (134), Expect = 3e-07
Identities = 76/320 (23%), Positives = 143/320 (44%), Gaps = 60/320 (18%)
Query: 831 MKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAK------------------RK 872
M LF K++ + E EK++ M++E + ++++ +S+AK R+
Sbjct: 1152 MSLFLKLQKRVTELEQEKQV--MQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQ 1209
Query: 873 ELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEE 932
ELE + L E N+L+ + +S + A + + QL + +E+ R E+
Sbjct: 1210 ELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLME-QLTSVSEELDVRKEEVLI 1268
Query: 933 INAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAK 992
+ ++L ++K ++ + + K + D + L V+K K E + + GL ET
Sbjct: 1269 LRSQLVSQKEAIQPK--DDKNTMTDSTILLEDVQKMKDKGE-----IAQAYIGLKETNRL 1321
Query: 993 LTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDL------ESSLEQE---- 1042
L + ++ + +H+ + L+ E + N + +L Q L E+SL+ E
Sbjct: 1322 LESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRL 1381
Query: 1043 KKLRVDL-------ERNKRKLEGDLKLAQESILDLE-------NDKQQLDERL------- 1081
+DL ++ RKL+ LK+ + I +LE + Q +DE +
Sbjct: 1382 TNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPR 1441
Query: 1082 KKKDFEYCQLQSKVEDEQTL 1101
K+KDF+ L+ K EDEQ L
Sbjct: 1442 KEKDFQ-GMLEYKKEDEQKL 1460
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 583 bits (1502), Expect = e-166
Identities = 468/1600 (29%), Positives = 797/1600 (49%), Gaps = 180/1600 (11%)
Query: 36 TYCFVVDSKEEYAKGKI-KSSQDGKVTVETE-DNRTLVVKPEDV------YAMNPPKFDR 87
T ++ D E + ++ K ++G +++ ++ T++ P DV + NP
Sbjct: 11 TRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVG 70
Query: 88 IEDMAMLTHLNEPAVLYNLKDRYT-SWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGK 146
D+ L++L+EPAVL+NLK R+ S IYTY G+ V +NPY+ LP+Y +V+ Y G+
Sbjct: 71 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130
Query: 147 KRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLA 206
+ PHIF++++ AY+ M D +NQSI+++GESGAGKTV+ K ++YFAT+
Sbjct: 131 NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGG----- 185
Query: 207 KKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 266
S + +E+++++++P++EA GNAKT RNDNSSRFGK+I+I F + A++ T
Sbjct: 186 ----SASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRT 241
Query: 267 YLLEKSRVTFQLKAERSYHIFYQILSNKK-PELIELLLITTNPYDYPFISQG-EILVASI 324
YLLEKSRV FQ ER+YHIFYQ+ + PE EL L T+ D+ + SQG + + +
Sbjct: 242 YLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELAL--TSAEDFFYTSQGGDTSIEGV 299
Query: 325 DDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTE--VA 382
DDAE+ T A +LG + ++K+ +++H G++ QAE DG ++
Sbjct: 300 DDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAI-------QAERDGDSCSIS 352
Query: 383 DKTAYL------MGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKL 436
+ YL +G+ S + LC ++ +E K ++ QV +A NAL+K +Y +L
Sbjct: 353 PQDVYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQL 412
Query: 437 FLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFV 496
F W+V IN+ L T L + FIGVLDI GFE FE NS EQ CIN+ NEKLQQ FN H+F
Sbjct: 413 FGWIVEHINKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFK 472
Query: 497 LEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQ 556
LEQEEY KE I WT IDF D CI+LIE +GI +L+EEC PK TD ++ KLYD+
Sbjct: 473 LEQEEYMKEQIPWTLIDF-YDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDR 531
Query: 557 HLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNR 616
H S +FQKP++ + F ++H+A V+Y G+LEKN+D + E + + + S
Sbjct: 532 H-SSSQHFQKPRM----SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFP 586
Query: 617 LLAHLY-----ATFATADADSGKKKVAKKKG---------SSFQTVSALFRENLNKLMSN 662
L+A L+ AT K++ + +TV FR +L+ LM
Sbjct: 587 LVADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMET 646
Query: 663 LRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQR 722
L T PH+VRCI PN+ K P + + QLR GVLE IRI G+P+R Y DF R
Sbjct: 647 LNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNR 706
Query: 723 YRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRL 782
YRVL E D K C +L ++ D +++FG TK+FF+AG + LE++R D+
Sbjct: 707 YRVLVKKR--ELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKF 764
Query: 783 AKLITRTQAVCRGFLMRVEFQKMVQRRESI--FCIQYNIR----SFMNVKHWPWMKLFFK 836
Q RG+L +V++ ++ ++ +C + R ++ ++ ++
Sbjct: 765 RTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYR 824
Query: 837 IKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAES 896
++ ++ + + A + + F T+ + ++ +E K T+ +K+ +
Sbjct: 825 MQRARQAYQRVRRAAVVIQAF--TRAMFVRRTYRQVLMEHKATTI--QKHVRGWMARRHF 880
Query: 897 ENLLDAE---ERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKK 953
+ L DA + +++KA+ +L+A ++ AE + +N +E++ +L++
Sbjct: 881 QRLRDAAIVIQCAFRMLKARRELKA-LRIEARSAEHLKRLNV-------GMENKVVQLQR 932
Query: 954 DIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIA-KLTREKKALQEAHQQALDDLQ 1012
ID+ + K L+E+LS T ++ R KK L Q +D
Sbjct: 933 KIDE--------------QNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGED-- 976
Query: 1013 AEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLK-----LAQESI 1067
T +L+++VE L + L++ R LE + + +L+ L QE+
Sbjct: 977 -----------TSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENA 1025
Query: 1068 LDLENDKQQLDERL--KKKDFEYCQ-------LQSKVEDEQTLGLQFQKKIKELQARIEE 1118
L L+++K+QL+ ++ + KD E+ Q ++ ++E+E++ K+ +L+ R +
Sbjct: 1026 L-LKDEKEQLNNQILCQSKD-EFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDN 1083
Query: 1119 LEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRD 1178
L +E+ KQ + R S ++ + + E+ +A +
Sbjct: 1084 LRDEM--------TIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDA-----LQQ 1130
Query: 1179 LEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMES 1238
+EE L+ AM + K V EL ++ LQ +K E++ S+ K++ + + ++
Sbjct: 1131 VEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSK-KVQAEPPQTDID- 1188
Query: 1239 VSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESI 1298
N + +L+ Q E +N++++ L+EL + T+ + +
Sbjct: 1189 ---LDPNADLAYNSLKRQ--ELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLL 1243
Query: 1299 VSQLSRSKQAFTQQTEE---LKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGK 1355
++QL + + + EE L+ Q+ ++ + A +A + + +QE
Sbjct: 1244 LNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDA 1303
Query: 1356 AELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASL 1415
E + + NS+ W + EL A + L Q + E Q++A SL
Sbjct: 1304 IEAYHGVCQTNSKTEDW------GYLNEDGELGLAYQGLKQVARLLEAQLQA-----QSL 1352
Query: 1416 EKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKES 1475
E + EVE L +E +L +DK+Q+ F + L E+Q E + S
Sbjct: 1353 EH-----EEEVEHLKAQLE---ALKEEMDKQQQTFCQTL----LLSPEAQVEFGVQQEIS 1400
Query: 1476 RSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADL--TEQIAENGKTIHELEKSRKQ 1533
R L+ E LK E+ +K++ K ++ DL + +A++ + HEL + +
Sbjct: 1401 R-LTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNR-QVT 1458
Query: 1534 IELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEI 1573
++ ++ D Q LE H+E + L I+ +T +K ++
Sbjct: 1459 VQRKEKDFQGMLE------YHKEDEALLIRNLVTDLKPQM 1492
Score = 55.8 bits (133), Expect = 4e-07
Identities = 89/357 (24%), Positives = 156/357 (43%), Gaps = 40/357 (11%)
Query: 1601 ALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDD 1660
AL E RS RL ME + +++ ++ N++ +TL SV T + +
Sbjct: 905 ALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEF-KTLSEQLSVT-----TSTYTME 958
Query: 1661 ALRGQEDLKE-QLAIVERRANLLQAEVEELRATLEQTERARKLAE----QELLDSNERVQ 1715
R +++L Q + E + LQ EVE LR L++ RK+ E +E + +RV
Sbjct: 959 VERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVA 1018
Query: 1716 LLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQD 1775
L +N L K++L ++ QS+ E A + E KK + + + L KE
Sbjct: 1019 DLEQENALLKDEKEQLNNQIL-CQSKDEFAQNSVK--ENLMKKELEEERSRYQNLVKEY- 1074
Query: 1776 TSAHLERMKKNLEQTVKDLQ----HRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQ 1831
+ LE+ NL + ++ HR + + Q +L+ + I + E L+ +
Sbjct: 1075 --SQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVE 1132
Query: 1832 ----KKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAE--- 1884
+K + K ++RV+EL E++RK +LQ ++K + + S K QAE
Sbjct: 1133 EIGLEKAAMDMTVFLKLQKRVREL----EQERK---KLQVQLEKRE-QQDSKKVQAEPPQ 1184
Query: 1885 -EADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESEE 1940
+ D NA L + ELE ++ ++ +N+LR D + H S +
Sbjct: 1185 TDIDLDPNADLAYNSLKRQELESENKK---LKNDLNELRKAVADQATQNNSSHGSPD 1238
Score = 37.7 bits (86), Expect = 0.11
Identities = 45/199 (22%), Positives = 89/199 (44%), Gaps = 27/199 (13%)
Query: 1707 LLDSNERVQLLHTQNTSLIHTKKK---LETDLMQLQSEVEDASRDARNAEEKAKKAITDA 1763
+L + ++ L + S H K+ +E ++QLQ ++++ +++ + E+ +
Sbjct: 896 MLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTY 955
Query: 1764 AMMAEELKKE---------QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ 1814
M E LKKE +DTS R+++ +E +LQ R ++ ++
Sbjct: 956 TMEVERLKKELVHYQQSPGEDTSL---RLQEEVESLRTELQ-RAHSERKILEDAHSREKD 1011
Query: 1815 KLETRIRELEFE---LEGEQKKNTESVKGLRKYE---RRVKE--LTYQSEEDRKNVLRLQ 1866
+L R+ +LE E L+ E+++ + K E VKE + + EE+R R Q
Sbjct: 1012 ELRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERS---RYQ 1068
Query: 1867 DLVDKLQVKVKSYKRQAEE 1885
+LV + + Y +E
Sbjct: 1069 NLVKEYSQLEQRYDNLRDE 1087
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 504 bits (1298), Expect = e-142
Identities = 435/1701 (25%), Positives = 823/1701 (48%), Gaps = 234/1701 (13%)
Query: 57 DGKVTVETE-DNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMI 115
+GKV V+ + D L V +DV N P DR+ED+A L +LNE +VL+ L+ RY + ++
Sbjct: 375 EGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLL 434
Query: 116 YTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSI 175
+TY+G + + P VY+ +V+ ++G +R++ PHI++++ AY+ ML R++QSI
Sbjct: 435 HTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSI 494
Query: 176 LITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAK 235
++ G SG+GKT + + ++QY ATIA +K+ + Q + LLEAFGN+
Sbjct: 495 ILLGSSGSGKTTSCQHLVQYLATIAGISG------NKVFSVEKWQALYT--LLEAFGNSP 546
Query: 236 TVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILS--- 292
T+ N N++RF + + + F G++ASA I+T LLEK RV + +E ++++FY +L+
Sbjct: 547 TIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGD 606
Query: 293 -NKKPELIELLLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLY 351
+ EL L N + +++ E + A++ +A+ +LG +P+E+ +
Sbjct: 607 GTLRTELHLNHLAENNVFGIVPLAKPEEKQKA---AQQFSKLQAAMKVLGISPDEQKACW 663
Query: 352 KLTGAVMHYGNMKFKQKQREEQAEPDGT-EVADKTAYLMGLNSSDLLKALCFPRVKVGN- 409
+ A+ H G ++ E + E A K AYL+G + +L A+ + K G
Sbjct: 664 FILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGTL 723
Query: 410 ----------EYVTKGQTVDQVHHAVNAL---SKSVYEKLFLWMVTRINQQLDTKLPRQH 456
E G A+ L + +Y +LF +V+ +N+ L +
Sbjct: 724 QRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLC 783
Query: 457 FIGVLDIAGFEIFEYN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWT 510
+ ++D GF+ E S E+LC N+T ++LQ+ F+ FV E E YK+E IE
Sbjct: 784 SMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELA 843
Query: 511 FIDF---------GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKLYD 555
F D +D A+ L+ ++ G+ +LEEE + P A++ + +L+
Sbjct: 844 FDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFS 903
Query: 556 QHLGKSNNFQKPK--VVKGRAEAHFSLIHYAGT--VDYSVSGWLEKNK-DPLNETVVGLY 610
+ G +K + ++ HF L H GT V+Y+V+GWL K +P + L
Sbjct: 904 YY-GPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLL 962
Query: 611 QKSSNRLLAHLY---ATFATADADS-----GKKKVAKKKGSSFQT-----VSALFRENL- 656
Q S +++++L+ A AT + S G ++A ++ +S + ++A+ +++L
Sbjct: 963 QDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLC 1022
Query: 657 -------NKLMSNLRTTHPHFVRCIIP--------------------NETKTPGA----- 684
+ L+ ++ + HFV C +P +E P
Sbjct: 1023 IQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEA 1082
Query: 685 ----MEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQ----F 736
++ L+ QLR + +L+ +R+ R+G+P+ +++ +F++R+ VL +
Sbjct: 1083 GLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIV 1142
Query: 737 IDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGF 796
+D ++A E+LL +D++ + G ++VFF+AG L LEE RD++ ++ +T QA CRG+
Sbjct: 1143 VDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGY 1202
Query: 797 LMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEE 856
L R F+K + +I C+Q NI+ VK WPW KLF ++PL++ +E+++ EE
Sbjct: 1203 LARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEE 1262
Query: 857 FQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQL 916
Q+ + +L K+E +R EL L ++L ++ E + E QL+ A
Sbjct: 1263 IQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDER----NTGESASQLLDA---- 1314
Query: 917 EAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA-----KVEKEKHA 971
E ER E+E+ EL + L+ + ++ ++ + L A +V+ +
Sbjct: 1315 -----ETAERLRAEKEMK-ELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAG 1368
Query: 972 TENKVKNLTEELSGLDETIAKLTREKKALQEAHQQ-------ALDDLQAEEDK----VNS 1020
E ++K + +D T +L +E + E QQ L DLQA+ ++ +
Sbjct: 1369 GEWRLK-YERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQ 1427
Query: 1021 LNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDER 1080
L K +L +++D + LE ++ +LE+ +R+ + +L A E + + +K Q ++
Sbjct: 1428 LKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE---EAQREKLQREKL 1484
Query: 1081 LKKKDF---EYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQR 1137
++KD E L+ ++E++ F +K+ L+A ++++ + + A+ AK +KQ
Sbjct: 1485 QREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQL 1544
Query: 1138 SDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKH 1197
D ++++ E L+E G LE+A L+ E + +R+ H
Sbjct: 1545 RDLEAKVKDQEEELDEQAGTIQM------------------LEQAKLRLEMEMERMRQTH 1586
Query: 1198 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQL 1257
+ + E++ + +Q +K+ + ++++++ + V + K LE TL DQ+
Sbjct: 1587 SKEMESRDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV 1643
Query: 1258 SEARGKNE-----EIQRSLSELTTQKSRL---------QTEAGELSRQLEEKESIVSQLS 1303
+ ++E +++R+ + L + L + E +L QLEE E +
Sbjct: 1644 NRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAV 1703
Query: 1304 RSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALS 1363
++++A + E+L Q+++ KAK AL L + + + ++ + EE+QE EL +
Sbjct: 1704 KARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNEL---MK 1760
Query: 1364 KANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQ 1423
K + VAQ A + LAQ + D + Q+E N + L++ Q LQ
Sbjct: 1761 KHKAAVAQ------------------ASRDLAQ-INDLQAQLEEANKEKQELQEKLQALQ 1801
Query: 1424 GEVEDL---MVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLST 1480
+VE L MVD SL + + K R + L +T+ + ++ L + LKE+
Sbjct: 1802 SQVEFLEQSMVD----KSLVSRQEAKIRELETRLEFERTQVKRLES-LASRLKEN----- 1851
Query: 1481 ELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKAD 1540
+ KL ++ + K +NK L++++ D E++ E + E E SRK+ ELE
Sbjct: 1852 -MEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELAR--KEAEASRKKHELE--- 1905
Query: 1541 IQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEE-----IEQLKRNYQRTV 1595
+ LE EAA + +A + + +++ I+ ++ + E ++ + YQ+
Sbjct: 1906 --MDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSLQDMVTKYQKRK 1963
Query: 1596 ETMQ--SALDAEVRSRNEAIR 1614
++ S +D+E+ R + ++
Sbjct: 1964 NKLEGDSDVDSELEDRVDGVK 1984
Score = 196 bits (497), Expect = 2e-49
Identities = 174/695 (25%), Positives = 330/695 (47%), Gaps = 52/695 (7%)
Query: 1253 LEDQLSEA--RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFT 1310
+E QLSE R K+EEIQ+ S+L + + E EL + ES +S+L+
Sbjct: 1247 IEVQLSEEQIRNKDEEIQQLRSKL----EKAEKERNELRLNSDRLESRISELTSELTDER 1302
Query: 1311 QQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYE--EEQEGKAELQRALSKANSE 1368
E + L+ E + ++ + D L++Q E E + +A L RA ++ N E
Sbjct: 1303 NTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRA-AEINGE 1361
Query: 1369 V------AQWRTKYETDAIQ--------------RTEELEEAKKKLAQRLQDSEEQVEAV 1408
V +WR KYE + + E ++ K++L +RL D + E
Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421
Query: 1409 NAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAEL 1468
L+K QRL E++D + +E L+KKQR FD L++ + + + +
Sbjct: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481
Query: 1469 EASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELE 1528
E +E L E F LK EE + ++ +LE E+ D++ Q +++ ++ +++
Sbjct: 1482 EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVK 1541
Query: 1529 KSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLK 1588
K + +E + D + L+E ++ E LR+++E+ +++ +++ +DEE+E+ +
Sbjct: 1542 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1601
Query: 1589 RNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETL-KHLRSV 1647
++ Q+ ++ M+ L+ E + + +R K+++EG L + Q++ + ++ + L K L+
Sbjct: 1602 QSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRT 1661
Query: 1648 QGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQEL 1707
+ L D QL LD L+ K ++A L+ ++EE T +ARK E E+
Sbjct: 1662 KALLADAQLMLDH-LKNSAPSKREIA-------QLKNQLEESEFTCAAAVKARKAMEVEI 1713
Query: 1708 LDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMA 1767
D + ++ + T+L +L+ + ++Q+ +E+ D +K K A+ A +
Sbjct: 1714 EDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQA---S 1770
Query: 1768 EELKKEQDTSAHLE---RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELE 1824
+L + D A LE + K+ L++ ++ LQ +++ EQ + K + + E +IRELE
Sbjct: 1771 RDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQEAKIRELE 1828
Query: 1825 FELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQA- 1883
LE E+ + VK L R+KE + E+R + ++ + +++ R
Sbjct: 1829 TRLEFERTQ----VKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTK 1884
Query: 1884 EEADEQANAHLTKFRKAQHELEEAEERADIAESQV 1918
EE E A RK +HELE E + A +
Sbjct: 1885 EEMGELARKEAEASRK-KHELEMDLESLEAANQSL 1918
Score = 166 bits (421), Expect = 2e-40
Identities = 196/815 (24%), Positives = 367/815 (45%), Gaps = 95/815 (11%)
Query: 1008 LDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESI 1067
L ++Q E+++ NK +++++ L S LE+ +K R +L N +LE + +
Sbjct: 1246 LIEVQLSEEQIR--NK-----DEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSEL 1298
Query: 1068 LDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAER 1127
D N + + L + E + + ++++ QT + L+ ++E +E E+ R
Sbjct: 1299 TDERNTGESASQLLDAETAERLRAEKEMKELQT-------QYDALKKQMEVMEMEVMEAR 1351
Query: 1128 ATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLK--LRRDLEEATLQ 1185
RA ++ E+++ ++AGG + E RE +F K L+++ E+
Sbjct: 1352 LIRA------AEINGEVDD-----DDAGGEWRLKYE-RAVREVDFTKKRLQQEFEDKLEV 1399
Query: 1186 HEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKAN 1245
+ L ++ D A+ E QR Q+L+K+ E+ D +E
Sbjct: 1400 EQQNKRQLERRLGDLQADSEES----QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE 1455
Query: 1246 LEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRS 1305
LEK R + +LS+A + + + +L +K L EA L +QLEEK+ ++
Sbjct: 1456 LEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIA----- 1510
Query: 1306 KQAFTQQTEELKRQLEE----ENKAKNALAHALQSSRHDCDLLREQYEE--EQEGKAE-L 1358
FTQ+ L+ +L++ E+K + +LA + R +++Q EE EQ G + L
Sbjct: 1511 --GFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQML 1568
Query: 1359 QRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKT 1418
++A + E+ + R + + R EE+EEA++ ++L+ E Q+E + +
Sbjct: 1569 EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628
Query: 1419 KQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSL 1478
K+ L+G++ L V R + + ++ K L K ++Q L+ LK S
Sbjct: 1629 KRELEGKLATLSDQVNRRDF------ESEKRLRKDLKRTKALLADAQLMLD-HLKNSAPS 1681
Query: 1479 STELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEK 1538
E+ +LKN EE+ + K +E EI DL QI + K LE+ +++ EK
Sbjct: 1682 KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK 1741
Query: 1539 ADIQLALEE----------------AEAALEHEEAKILRIQLE-LTQVKSEIDRKIAEKD 1581
+IQ LEE A+A+ + + L+ QLE + K E+ K+
Sbjct: 1742 NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQ 1801
Query: 1582 EEIEQLKRNY-QRTVETMQSALDAEVRSRNE------------AIRLKKKMEGDLNEIEI 1628
++E L+++ +++ + Q A E+ +R E A RLK+ ME E +
Sbjct: 1802 SQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQ 1861
Query: 1629 QLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEE 1688
+++ NR+ + + +Q QL+DT+ + + R + + + +E L+A +
Sbjct: 1862 RIAAENREKEQN----KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQS 1917
Query: 1689 LRATLEQTERA---RKLAEQELLDSNERVQLLHTQN---TSLIHTKKKLETDLMQLQSEV 1742
L+A L+ + + A ++ ++S+E L+++ T K KLE D + SE+
Sbjct: 1918 LQADLKLAFKRIGDLQAAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEGD-SDVDSEL 1976
Query: 1743 EDASRDARNAEEKAKKAITDAAMMAEELKKEQDTS 1777
ED ++ K K + AA LK TS
Sbjct: 1977 EDRVDGVKSWLSK-NKGPSKAASDDGSLKSSSPTS 2010
Score = 84.7 bits (208), Expect = 8e-16
Identities = 79/327 (24%), Positives = 155/327 (47%), Gaps = 29/327 (8%)
Query: 1626 IEIQLSHAN-RQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQA 1684
IE+QLS R E ++ LRS L+ A + + +L+ +E R + L +
Sbjct: 1247 IEVQLSEEQIRNKDEEIQQLRS----------KLEKAEKERNELRLNSDRLESRISELTS 1296
Query: 1685 EVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQ------- 1737
E+ + R T E + E L + + ++ L TQ +L + +E ++M+
Sbjct: 1297 ELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAA 1356
Query: 1738 -LQSEVEDASRDARNAEEKAK--KAITDAAMMAEELKKEQDTSAHLERM-KKNLEQTVKD 1793
+ EV+D D E + K +A+ + + L++E + +E+ K+ LE+ + D
Sbjct: 1357 EINGEVDD---DDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGD 1413
Query: 1794 LQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTY 1853
LQ +E+++ AL+ KK+ Q+L +++ + LEG+Q +N E K R+++ + +
Sbjct: 1414 LQADSEESQR-ALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE 1472
Query: 1854 QSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADI 1913
+++ ++ +LQ D L + S K+Q EE D K + EL++ +
Sbjct: 1473 EAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESK 1532
Query: 1914 AESQVNKLRAKTRDFTSSRMVVHESEE 1940
E+ + K++ + RD + V + EE
Sbjct: 1533 DEASLAKVKKQLRDLEAK---VKDQEE 1556
Score = 50.1 bits (118), Expect = 2e-05
Identities = 60/245 (24%), Positives = 114/245 (46%), Gaps = 40/245 (16%)
Query: 847 EKEMATMKEEFQKTKDELAKSE---AKRKELEEKLVTLVQEKNDLQLQVQA-ESENLLDA 902
E++ M E +K K +A++ A+ +L+ +L +EK +LQ ++QA +S+
Sbjct: 1749 EEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLE 1808
Query: 903 EERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTL 962
+ D+ + ++ EAKI+E+ R E E L + +L++ +L ++ D
Sbjct: 1809 QSMVDKSLVSR--QEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAE 1866
Query: 963 AKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQ------EAHQQALD------- 1009
+ +++ + ++++ EE+ L A+ +R+K L+ EA Q+L
Sbjct: 1867 NREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAF 1926
Query: 1010 ----DLQA----------EEDKVNSLNKTKSKLEQQVEDLE--SSLEQEKKLRVD----- 1048
DLQA ED +NSL +K +++ LE S ++ E + RVD
Sbjct: 1927 KRIGDLQAAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEGDSDVDSELEDRVDGVKSW 1986
Query: 1049 LERNK 1053
L +NK
Sbjct: 1987 LSKNK 1991
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 502 bits (1292), Expect = e-141
Identities = 430/1673 (25%), Positives = 815/1673 (48%), Gaps = 222/1673 (13%)
Query: 57 DGKVTVETE-DNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMI 115
+GKV V+ + D L V +DV N P DR+ED+A L +LNE +VL+ L+ RY + ++
Sbjct: 375 EGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLL 434
Query: 116 YTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSI 175
+TY+G + + P VY+ +V+ ++G +R++ PHI++++ AY+ ML R++QSI
Sbjct: 435 HTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSI 494
Query: 176 LITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAK 235
++ G SG+GKT + + ++QY ATIA +K+ + Q + LLEAFGN+
Sbjct: 495 ILLGSSGSGKTTSCQHLVQYLATIAGISG------NKVFSVEKWQALYT--LLEAFGNSP 546
Query: 236 TVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILS--- 292
T+ N N++RF + + + F G++ASA I+T LLEK RV + +E ++++FY +L+
Sbjct: 547 TIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGD 606
Query: 293 -NKKPELIELLLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLY 351
+ EL L N + +++ E + A++ +A+ +LG +P+E+ +
Sbjct: 607 GTLRTELHLNHLAENNVFGIVPLAKPEEKQKA---AQQFSKLQAAMKVLGISPDEQKACW 663
Query: 352 KLTGAVMHYGNMKFKQKQREEQAEPDGT-EVADKTAYLMGLNSSDLLKALCFPRVKVGN- 409
+ A+ H G ++ E + E A K AYL+G + +L A+ + K G
Sbjct: 664 FILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGTL 723
Query: 410 ----------EYVTKGQTVDQVHHAVNAL---SKSVYEKLFLWMVTRINQQLDTKLPRQH 456
E G A+ L + +Y +LF +V+ +N+ L +
Sbjct: 724 QRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLC 783
Query: 457 FIGVLDIAGFEIFEYN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWT 510
+ ++D GF+ E S E+LC N+T ++LQ+ F+ FV E E YK+E IE
Sbjct: 784 SMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELA 843
Query: 511 FIDF---------GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKLYD 555
F D +D A+ L+ ++ G+ +LEEE + P A++ + +L+
Sbjct: 844 FDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFS 903
Query: 556 QHLGKSNNFQKPK--VVKGRAEAHFSLIHYAGT--VDYSVSGWLEKNK-DPLNETVVGLY 610
+ G +K + ++ HF L H GT V+Y+V+GWL K +P + L
Sbjct: 904 YY-GPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLL 962
Query: 611 QKSSNRLLAHLY---ATFATADADS-----GKKKVAKKKGSSFQT-----VSALFRENL- 656
Q S +++++L+ A AT + S G ++A ++ +S + ++A+ +++L
Sbjct: 963 QDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLC 1022
Query: 657 -------NKLMSNLRTTHPHFVRCIIP--------------------NETKTPGA----- 684
+ L+ ++ + HFV C +P +E P
Sbjct: 1023 IQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEA 1082
Query: 685 ----MEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQ----F 736
++ L+ QLR + +L+ +R+ R+G+P+ +++ +F++R+ VL +
Sbjct: 1083 GLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIV 1142
Query: 737 IDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGF 796
+D ++A E+LL +D++ + G ++VFF+AG L LEE RD++ ++ +T QA CRG+
Sbjct: 1143 VDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGY 1202
Query: 797 LMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEE 856
L R F+K + +I C+Q NI+ VK WPW KLF ++PL++ +E+++ EE
Sbjct: 1203 LARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEE 1262
Query: 857 FQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQL 916
Q+ + +L K+E +R EL L ++L ++ E + E QL+ A
Sbjct: 1263 IQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDER----NTGESASQLLDA---- 1314
Query: 917 EAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA-----KVEKEKHA 971
E ER E+E+ EL + L+ + ++ ++ + L A +V+ +
Sbjct: 1315 -----ETAERLRAEKEMK-ELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAG 1368
Query: 972 TENKVKNLTEELSGLDETIAKLTREKKALQEAHQQ-------ALDDLQAEEDK----VNS 1020
E ++K + +D T +L +E + E QQ L DLQA+ ++ +
Sbjct: 1369 GEWRLK-YERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQ 1427
Query: 1021 LNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDER 1080
L K +L +++D + LE ++ +LE+ +R+ + +L A E + + +K Q ++
Sbjct: 1428 LKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE---EAQREKLQREKL 1484
Query: 1081 LKKKDF---EYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQR 1137
++KD E L+ ++E++ F +K+ L+A ++++ + + A+ AK +KQ
Sbjct: 1485 QREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQL 1544
Query: 1138 SDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKH 1197
D ++++ E L+E G LE+A L+ E + +R+ H
Sbjct: 1545 RDLEAKVKDQEEELDEQAGTIQM------------------LEQAKLRLEMEMERMRQTH 1586
Query: 1198 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQL 1257
+ + E++ + +Q +K+ + ++++++ + V + K LE TL DQ+
Sbjct: 1587 SKEMESRDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV 1643
Query: 1258 SEARGKNE-----EIQRSLSELTTQKSRL---------QTEAGELSRQLEEKESIVSQLS 1303
+ ++E +++R+ + L + L + E +L QLEE E +
Sbjct: 1644 NRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAV 1703
Query: 1304 RSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALS 1363
++++A + E+L Q+++ KAK AL L + + + ++ + EE+QE EL +
Sbjct: 1704 KARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNEL---MK 1760
Query: 1364 KANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQ 1423
K + VAQ A + LAQ + D + Q+E N + L++ Q LQ
Sbjct: 1761 KHKAAVAQ------------------ASRDLAQ-INDLQAQLEEANKEKQELQEKLQALQ 1801
Query: 1424 GEVEDL---MVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLST 1480
+VE L MVD SL + + K R + L +T+ + ++ L + LKE+ T
Sbjct: 1802 SQVEFLEQSMVD----KSLVSRQEAKIRELETRLEFERTQVKRLES-LASRLKENMEKLT 1856
Query: 1481 ELFKLKNAYE-EALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELE-- 1537
E + A E +Q + ++R+ ++ ++E+ +L + AE + HELE + +E
Sbjct: 1857 EERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQ 1916
Query: 1538 --KADIQLALE---EAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIE 1585
+AD++LA + + +AA+E E L ++ S++D ++ ++ + ++
Sbjct: 1917 SLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVK 1969
Score = 196 bits (497), Expect = 2e-49
Identities = 174/695 (25%), Positives = 330/695 (47%), Gaps = 52/695 (7%)
Query: 1253 LEDQLSEA--RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFT 1310
+E QLSE R K+EEIQ+ S+L + + E EL + ES +S+L+
Sbjct: 1247 IEVQLSEEQIRNKDEEIQQLRSKL----EKAEKERNELRLNSDRLESRISELTSELTDER 1302
Query: 1311 QQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYE--EEQEGKAELQRALSKANSE 1368
E + L+ E + ++ + D L++Q E E + +A L RA ++ N E
Sbjct: 1303 NTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRA-AEINGE 1361
Query: 1369 V------AQWRTKYETDAIQ--------------RTEELEEAKKKLAQRLQDSEEQVEAV 1408
V +WR KYE + + E ++ K++L +RL D + E
Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421
Query: 1409 NAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAEL 1468
L+K QRL E++D + +E L+KKQR FD L++ + + + +
Sbjct: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481
Query: 1469 EASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELE 1528
E +E L E F LK EE + ++ +LE E+ D++ Q +++ ++ +++
Sbjct: 1482 EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVK 1541
Query: 1529 KSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLK 1588
K + +E + D + L+E ++ E LR+++E+ +++ +++ +DEE+E+ +
Sbjct: 1542 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1601
Query: 1589 RNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETL-KHLRSV 1647
++ Q+ ++ M+ L+ E + + +R K+++EG L + Q++ + ++ + L K L+
Sbjct: 1602 QSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRT 1661
Query: 1648 QGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQEL 1707
+ L D QL LD L+ K ++A L+ ++EE T +ARK E E+
Sbjct: 1662 KALLADAQLMLDH-LKNSAPSKREIA-------QLKNQLEESEFTCAAAVKARKAMEVEI 1713
Query: 1708 LDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMA 1767
D + ++ + T+L +L+ + ++Q+ +E+ D +K K A+ A +
Sbjct: 1714 EDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQA---S 1770
Query: 1768 EELKKEQDTSAHLE---RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELE 1824
+L + D A LE + K+ L++ ++ LQ +++ EQ + K + + E +IRELE
Sbjct: 1771 RDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQEAKIRELE 1828
Query: 1825 FELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQA- 1883
LE E+ + VK L R+KE + E+R + ++ + +++ R
Sbjct: 1829 TRLEFERTQ----VKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTK 1884
Query: 1884 EEADEQANAHLTKFRKAQHELEEAEERADIAESQV 1918
EE E A RK +HELE E + A +
Sbjct: 1885 EEMGELARKEAEASRK-KHELEMDLESLEAANQSL 1918
Score = 165 bits (418), Expect = 4e-40
Identities = 194/811 (23%), Positives = 364/811 (44%), Gaps = 102/811 (12%)
Query: 1008 LDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESI 1067
L ++Q E+++ NK +++++ L S LE+ +K R +L N +LE + +
Sbjct: 1246 LIEVQLSEEQIR--NK-----DEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSEL 1298
Query: 1068 LDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAER 1127
D N + + L + E + + ++++ QT + L+ ++E +E E+ R
Sbjct: 1299 TDERNTGESASQLLDAETAERLRAEKEMKELQT-------QYDALKKQMEVMEMEVMEAR 1351
Query: 1128 ATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLK--LRRDLEEATLQ 1185
RA ++ E+++ ++AGG + E RE +F K L+++ E+
Sbjct: 1352 LIRA------AEINGEVDD-----DDAGGEWRLKYE-RAVREVDFTKKRLQQEFEDKLEV 1399
Query: 1186 HEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKAN 1245
+ L ++ D A+ E QR Q+L+K+ E+ D +E
Sbjct: 1400 EQQNKRQLERRLGDLQADSEES----QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE 1455
Query: 1246 LEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRS 1305
LEK R + +LS+A + + + +L +K L EA L +QLEEK+ ++
Sbjct: 1456 LEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIA----- 1510
Query: 1306 KQAFTQQTEELKRQLEE----ENKAKNALAHALQSSRHDCDLLREQYEE--EQEGKAE-L 1358
FTQ+ L+ +L++ E+K + +LA + R +++Q EE EQ G + L
Sbjct: 1511 --GFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQML 1568
Query: 1359 QRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKT 1418
++A + E+ + R + + R EE+EEA++ ++L+ E Q+E + +
Sbjct: 1569 EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628
Query: 1419 KQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSL 1478
K+ L+G++ L V R + + ++ K L K ++Q L+ LK S
Sbjct: 1629 KRELEGKLATLSDQVNRRDF------ESEKRLRKDLKRTKALLADAQLMLD-HLKNSAPS 1681
Query: 1479 STELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEK 1538
E+ +LKN EE+ + K +E EI DL QI + K LE+ +++ EK
Sbjct: 1682 KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK 1741
Query: 1539 ADIQLALEE----------------AEAALEHEEAKILRIQLE-LTQVKSEIDRKIAEKD 1581
+IQ LEE A+A+ + + L+ QLE + K E+ K+
Sbjct: 1742 NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQ 1801
Query: 1582 EEIEQLKRNY-QRTVETMQSALDAEVRSRNE------------AIRLKKKMEGDLNEIEI 1628
++E L+++ +++ + Q A E+ +R E A RLK+ ME E +
Sbjct: 1802 SQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQ 1861
Query: 1629 QLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEE 1688
+++ NR+ + + +Q QL+DT+ + + R + A R+ + L+ ++E
Sbjct: 1862 RIAAENREKEQN----KRLQRQLRDTKEEMGELARKE-------AEASRKKHELEMDLES 1910
Query: 1689 LRATLEQTERARKLAEQELLDSNERV--QLLHTQNTSLIHTKKKLETDLMQLQSEVEDAS 1746
L A + + KLA + + D + ++ +N LI+++ + D SE+ED
Sbjct: 1911 LEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVD-----SELEDRV 1965
Query: 1747 RDARNAEEKAKKAITDAAMMAEELKKEQDTS 1777
++ K K + AA LK TS
Sbjct: 1966 DGVKSWLSK-NKGPSKAASDDGSLKSSSPTS 1995
Score = 84.7 bits (208), Expect = 8e-16
Identities = 79/327 (24%), Positives = 155/327 (47%), Gaps = 29/327 (8%)
Query: 1626 IEIQLSHAN-RQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQA 1684
IE+QLS R E ++ LRS L+ A + + +L+ +E R + L +
Sbjct: 1247 IEVQLSEEQIRNKDEEIQQLRS----------KLEKAEKERNELRLNSDRLESRISELTS 1296
Query: 1685 EVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQ------- 1737
E+ + R T E + E L + + ++ L TQ +L + +E ++M+
Sbjct: 1297 ELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAA 1356
Query: 1738 -LQSEVEDASRDARNAEEKAK--KAITDAAMMAEELKKEQDTSAHLERM-KKNLEQTVKD 1793
+ EV+D D E + K +A+ + + L++E + +E+ K+ LE+ + D
Sbjct: 1357 EINGEVDD---DDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGD 1413
Query: 1794 LQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTY 1853
LQ +E+++ AL+ KK+ Q+L +++ + LEG+Q +N E K R+++ + +
Sbjct: 1414 LQADSEESQR-ALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE 1472
Query: 1854 QSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADI 1913
+++ ++ +LQ D L + S K+Q EE D K + EL++ +
Sbjct: 1473 EAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESK 1532
Query: 1914 AESQVNKLRAKTRDFTSSRMVVHESEE 1940
E+ + K++ + RD + V + EE
Sbjct: 1533 DEASLAKVKKQLRDLEAK---VKDQEE 1556
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 490 bits (1262), Expect = e-138
Identities = 344/1029 (33%), Positives = 520/1029 (50%), Gaps = 88/1029 (8%)
Query: 52 IKSSQDGKVTVETEDNRTLVVKPED---VYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKD 108
+K G+V V +++ + P++ + M+P +EDM L LNE +L NL
Sbjct: 28 VKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLLI 87
Query: 109 RYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLT 168
RY +IYTY+G V VNPY+ L +Y+PE + Y KK E PPHIF+I+DN Y M
Sbjct: 88 RYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKR 147
Query: 169 DRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLL 228
+ +Q +I+GESGAGKT +TK ++Q+ A I S +E Q++ A P+L
Sbjct: 148 NSRDQCCIISGESGAGKTESTKLILQFLAAI-----------SGQHSWIEQQVLEATPIL 196
Query: 229 EAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFY 288
EAFGNAKT+RNDNSSRFGK+I IHF G + A IE YLLEKSRV Q ER+YH+FY
Sbjct: 197 EAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFY 256
Query: 289 QILSNKKPELIELLLITTNPYDYPFISQGE-ILVASIDDAEELLATDSAIDILGFTPEEK 347
+L + + L + DY +++ G I D++E SA+ +L FT E
Sbjct: 257 CMLEGMSEDQKKKLGL-GQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTEN 315
Query: 348 SGLYKLTGAVMHYGNMKFKQKQRE--EQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRV 405
+ KL A++H GN++++ + E + E + A L+ +N DL+ L +
Sbjct: 316 WEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTL 375
Query: 406 KVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQL------DTKLPRQHFIG 459
E V+ + +Q +A K +Y +LF+W+V +IN + D K R+ IG
Sbjct: 376 ITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRS-IG 434
Query: 460 VLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLA 519
+LDI GFE F NS EQLCINF NE LQQFF H+F LEQEEY E I+W I+F +
Sbjct: 435 LLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQD 494
Query: 520 ACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFS 579
A + KPM I S+++EE FPK TDT+ +KL QH +N K E F
Sbjct: 495 ALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPP----KNNHETQFG 550
Query: 580 LIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYATFATADADSGKKKVAK 639
+ H+AG V Y G+LEKN+D L+ ++ L S N+ + ++ A++ K+
Sbjct: 551 INHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMGAETRKRS--- 607
Query: 640 KKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGV 699
T+S+ F+ +L LM L P FVRCI PNE K P + L + QLR +G+
Sbjct: 608 ------PTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGM 661
Query: 700 LEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKF 759
+E IRI R G+P R + +F +RYRVL P + D + C+++ ++ H ++
Sbjct: 662 METIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQI 721
Query: 760 GHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNI 819
G TK+F K LE RD + + Q V RGF R F K+ + + IQ +
Sbjct: 722 GKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKL---KNAATLIQRHW 778
Query: 820 RSFMNVKHWPWMKL-FFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKL 878
R K++ M+L F +++ L +S + ++ ++ + + ++ RK +L
Sbjct: 779 RGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQAR-CRAYLVRKAFRHRL 837
Query: 879 VTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELT 938
+ L VQA + ++ R Q ++A++ + +++ R +EE++ E++
Sbjct: 838 WAV--------LTVQAYARGMI--ARRLHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMS 885
Query: 939 AKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKK 998
AKK K E E ++ LA++ +E E K K + R KK
Sbjct: 886 AKKAKEEAERKHQER--------LAQLAREDAERELKEK--------------EAARRKK 923
Query: 999 ALQEAHQQALDDLQAEEDKVNSL---NKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRK 1055
L E ++A + D V+ + T L Q S E DLER +R+
Sbjct: 924 ELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFE-------DLERGRRE 976
Query: 1056 L-EGDLKLA 1063
+ E DL A
Sbjct: 977 MVEEDLDAA 985
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 490 bits (1262), Expect = e-138
Identities = 344/1029 (33%), Positives = 520/1029 (50%), Gaps = 88/1029 (8%)
Query: 52 IKSSQDGKVTVETEDNRTLVVKPED---VYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKD 108
+K G+V V +++ + P++ + M+P +EDM L LNE +L NL
Sbjct: 28 VKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLLI 87
Query: 109 RYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLT 168
RY +IYTY+G V VNPY+ L +Y+PE + Y KK E PPHIF+I+DN Y M
Sbjct: 88 RYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKR 147
Query: 169 DRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLL 228
+ +Q +I+GESGAGKT +TK ++Q+ A I S +E Q++ A P+L
Sbjct: 148 NSRDQCCIISGESGAGKTESTKLILQFLAAI-----------SGQHSWIEQQVLEATPIL 196
Query: 229 EAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFY 288
EAFGNAKT+RNDNSSRFGK+I IHF G + A IE YLLEKSRV Q ER+YH+FY
Sbjct: 197 EAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFY 256
Query: 289 QILSNKKPELIELLLITTNPYDYPFISQGE-ILVASIDDAEELLATDSAIDILGFTPEEK 347
+L + + L + DY +++ G I D++E SA+ +L FT E
Sbjct: 257 CMLEGMSEDQKKKLGL-GQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTEN 315
Query: 348 SGLYKLTGAVMHYGNMKFKQKQRE--EQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRV 405
+ KL A++H GN++++ + E + E + A L+ +N DL+ L +
Sbjct: 316 WEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTL 375
Query: 406 KVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQL------DTKLPRQHFIG 459
E V+ + +Q +A K +Y +LF+W+V +IN + D K R+ IG
Sbjct: 376 ITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRS-IG 434
Query: 460 VLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLA 519
+LDI GFE F NS EQLCINF NE LQQFF H+F LEQEEY E I+W I+F +
Sbjct: 435 LLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQD 494
Query: 520 ACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFS 579
A + KPM I S+++EE FPK TDT+ +KL QH +N K E F
Sbjct: 495 ALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPP----KNNHETQFG 550
Query: 580 LIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYATFATADADSGKKKVAK 639
+ H+AG V Y G+LEKN+D L+ ++ L S N+ + ++ A++ K+
Sbjct: 551 INHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMGAETRKRS--- 607
Query: 640 KKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGV 699
T+S+ F+ +L LM L P FVRCI PNE K P + L + QLR +G+
Sbjct: 608 ------PTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGM 661
Query: 700 LEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKF 759
+E IRI R G+P R + +F +RYRVL P + D + C+++ ++ H ++
Sbjct: 662 METIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQI 721
Query: 760 GHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNI 819
G TK+F K LE RD + + Q V RGF R F K+ + + IQ +
Sbjct: 722 GKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKL---KNAATLIQRHW 778
Query: 820 RSFMNVKHWPWMKL-FFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKL 878
R K++ M+L F +++ L +S + ++ ++ + + ++ RK +L
Sbjct: 779 RGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQAR-CRAYLVRKAFRHRL 837
Query: 879 VTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELT 938
+ L VQA + ++ R Q ++A++ + +++ R +EE++ E++
Sbjct: 838 WAV--------LTVQAYARGMI--ARRLHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMS 885
Query: 939 AKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKK 998
AKK K E E ++ LA++ +E E K K + R KK
Sbjct: 886 AKKAKEEAERKHQER--------LAQLAREDAERELKEK--------------EAARRKK 923
Query: 999 ALQEAHQQALDDLQAEEDKVNSL---NKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRK 1055
L E ++A + D V+ + T L Q S E DLER +R+
Sbjct: 924 ELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFE-------DLERGRRE 976
Query: 1056 L-EGDLKLA 1063
+ E DL A
Sbjct: 977 MVEEDLDAA 985
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 490 bits (1262), Expect = e-138
Identities = 344/1029 (33%), Positives = 520/1029 (50%), Gaps = 88/1029 (8%)
Query: 52 IKSSQDGKVTVETEDNRTLVVKPED---VYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKD 108
+K G+V V +++ + P++ + M+P +EDM L LNE +L NL
Sbjct: 28 VKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLLI 87
Query: 109 RYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLT 168
RY +IYTY+G V VNPY+ L +Y+PE + Y KK E PPHIF+I+DN Y M
Sbjct: 88 RYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKR 147
Query: 169 DRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLL 228
+ +Q +I+GESGAGKT +TK ++Q+ A I S +E Q++ A P+L
Sbjct: 148 NSRDQCCIISGESGAGKTESTKLILQFLAAI-----------SGQHSWIEQQVLEATPIL 196
Query: 229 EAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFY 288
EAFGNAKT+RNDNSSRFGK+I IHF G + A IE YLLEKSRV Q ER+YH+FY
Sbjct: 197 EAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFY 256
Query: 289 QILSNKKPELIELLLITTNPYDYPFISQGE-ILVASIDDAEELLATDSAIDILGFTPEEK 347
+L + + L + DY +++ G I D++E SA+ +L FT E
Sbjct: 257 CMLEGMSEDQKKKLGL-GQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTEN 315
Query: 348 SGLYKLTGAVMHYGNMKFKQKQRE--EQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRV 405
+ KL A++H GN++++ + E + E + A L+ +N DL+ L +
Sbjct: 316 WEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTL 375
Query: 406 KVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQL------DTKLPRQHFIG 459
E V+ + +Q +A K +Y +LF+W+V +IN + D K R+ IG
Sbjct: 376 ITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRS-IG 434
Query: 460 VLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLA 519
+LDI GFE F NS EQLCINF NE LQQFF H+F LEQEEY E I+W I+F +
Sbjct: 435 LLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEFTDNQD 494
Query: 520 ACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHFS 579
A + KPM I S+++EE FPK TDT+ +KL QH +N K E F
Sbjct: 495 ALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPP----KNNHETQFG 550
Query: 580 LIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYATFATADADSGKKKVAK 639
+ H+AG V Y G+LEKN+D L+ ++ L S N+ + ++ A++ K+
Sbjct: 551 INHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQADVAMGAETRKRS--- 607
Query: 640 KKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGV 699
T+S+ F+ +L LM L P FVRCI PNE K P + L + QLR +G+
Sbjct: 608 ------PTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGM 661
Query: 700 LEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKF 759
+E IRI R G+P R + +F +RYRVL P + D + C+++ ++ H ++
Sbjct: 662 METIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQI 721
Query: 760 GHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQYNI 819
G TK+F K LE RD + + Q V RGF R F K+ + + IQ +
Sbjct: 722 GKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKL---KNAATLIQRHW 778
Query: 820 RSFMNVKHWPWMKL-FFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKL 878
R K++ M+L F +++ L +S + ++ ++ + + ++ RK +L
Sbjct: 779 RGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQAR-CRAYLVRKAFRHRL 837
Query: 879 VTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELT 938
+ L VQA + ++ R Q ++A++ + +++ R +EE++ E++
Sbjct: 838 WAV--------LTVQAYARGMI--ARRLHQRLRAEYLWRLEAEKM--RLAEEEKLRKEMS 885
Query: 939 AKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKK 998
AKK K E E ++ LA++ +E E K K + R KK
Sbjct: 886 AKKAKEEAERKHQER--------LAQLAREDAERELKEK--------------EAARRKK 923
Query: 999 ALQEAHQQALDDLQAEEDKVNSL---NKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRK 1055
L E ++A + D V+ + T L Q S E DLER +R+
Sbjct: 924 ELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFE-------DLERGRRE 976
Query: 1056 L-EGDLKLA 1063
+ E DL A
Sbjct: 977 MVEEDLDAA 985
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 478 bits (1230), Expect = e-134
Identities = 314/950 (33%), Positives = 534/950 (56%), Gaps = 59/950 (6%)
Query: 52 IKSSQDGKVTVETEDNRTLVVKP-----EDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNL 106
+ S +G V T+ + K + V AM+P + ++DMA LT L+ +++YNL
Sbjct: 24 VNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEEGVDDMASLTELHGGSIMYNL 83
Query: 107 KDRYTSWMIYTYSGLFCVTVNPYKWLP-VYNPEVVEGYRGKKRQEAPPHIFSISDNAYQF 165
RY IYTY G +VNPY+ + +Y P +E Y + E PPHIF+I++ Y+
Sbjct: 84 FQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSRRHLGELPPHIFAIANECYRC 143
Query: 166 MLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATG-DLAKKKDSKMKGTLEDQIISA 224
+ +NQ ILI+GESGAGKT +TK ++++ + I+ +L+ K+ + +E I+ +
Sbjct: 144 LWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQSLELSLKEKTSC---VERAILES 200
Query: 225 NPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSY 284
+P++EAFGNAKTV N+NSSRFGKF++++ G + I YLLEK+RV Q ER+Y
Sbjct: 201 SPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIVDYLLEKNRVVRQNPGERNY 260
Query: 285 HIFYQILSNKKPELIELLLITTNPYDYPFISQ-GEILVASIDDAEELLATDSAIDILGFT 343
HIFY +L+ + E E ++T P +Y +++Q G + +I D E +A+D++ F+
Sbjct: 261 HIFYALLAGLEHEEREEFYLST-PENYHYLNQSGCVEDKTISDQESFREVITAMDVMQFS 319
Query: 344 PEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAY-----LMGLNSSDLLK 398
EE + +L ++H GN++F G +V+ KTA L+GL+ + L
Sbjct: 320 KEEVREVSRLLAGILHLGNIEF--------ITAGGAQVSFKTALGRSAELLGLDPTQLTD 371
Query: 399 ALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFI 458
AL + + E + V Q + ++L+ ++Y F W++ +IN ++ + I
Sbjct: 372 ALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKKINSRIKGNEDFKS-I 430
Query: 459 GVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDL 518
G+LDI GFE FE N EQ IN+ NEKLQ++FN H+F LEQ EY +EG+ W ID+ +D
Sbjct: 431 GILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYSREGLVWEDIDW-IDN 489
Query: 519 AACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAHF 578
C++LIEK +G+ +++ EE FP+ATD++ KL+ QH ++ + KP+V A +F
Sbjct: 490 GECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQH-ANNHFYVKPRV----AVNNF 544
Query: 579 SLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYATFATADADSGKKKVA 638
+ HYAG V Y V G LEKN+D + ++ L ++S + L+ ++ + K +
Sbjct: 545 GVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEHVSSRNNQDTLKCGS 604
Query: 639 KKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNG 698
K + TVS+ F+++L+ LM+ L +++P FVRCI PN K P + ++VL+QLR +G
Sbjct: 605 KHRR---PTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYSG 661
Query: 699 VLEGIRICRKGFPNRILYGDFKQRYRVLNAS-AIPEGQFIDSKKACEKLLASIDIDHTQY 757
+LE +RI + G+ R + DF +RY+VL + A+PE D + C LL D ++++
Sbjct: 662 MLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE----DVRGKCTSLLQLYDASNSEW 717
Query: 758 KFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQRRESIFCIQY 817
+ G TKVF + L LE+ R++ ++ +A GFL R +++K++ + IQ
Sbjct: 718 QLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLY---CVVIIQK 774
Query: 818 NIRSFMNVKHWPWMK----LFFK-IKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRK 872
N R+F+ + + +K +F K ++ + + +A +E+ +K K E + E K++
Sbjct: 775 NYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQE--EEEKKKR 832
Query: 873 ELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEE 932
E EE+ +E+ + +L+ Q E E E Q K Q EA++ E+ ++ ++
Sbjct: 833 EEEER--ERERERREAELRAQQEEETRKQQELEALQ----KSQKEAELTRELEKQKENKQ 886
Query: 933 INAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 982
+ E+ ++++ED + K+ +L LT A ++K + + +++ L EE
Sbjct: 887 VE-EILRLEKEIED--LQRMKEQQELSLTEASLQKLQERRDQELRRLEEE 933
Score = 53.5 bits (127), Expect = 2e-06
Identities = 57/216 (26%), Positives = 98/216 (45%), Gaps = 16/216 (7%)
Query: 1267 IQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKA 1326
IQ++ ++ L + + Q + + I ++ R A ++ EE K+Q EEE K
Sbjct: 772 IQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKK 831
Query: 1327 KNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEE 1386
+ + R + + LR Q EEE + EL+ AL K+ E R + ++ EE
Sbjct: 832 REEEERERERERREAE-LRAQQEEETRKQQELE-ALQKSQKEAELTRELEKQKENKQVEE 889
Query: 1387 LEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKK 1446
+ +K++ + LQ +EQ E ++ ASL+K ++R E+ L E AA +
Sbjct: 890 ILRLEKEI-EDLQRMKEQQE-LSLTEASLQKLQERRDQELRRL----EEEACRAAQEFLE 943
Query: 1447 QRNFDKVLAEWKTKCEESQAELEASLKESRSLSTEL 1482
NFD++ +E +E SL S+EL
Sbjct: 944 SLNFDEI--------DECVRNIERSLSVGSEFSSEL 971
Score = 45.1 bits (105), Expect = 7e-04
Identities = 52/232 (22%), Positives = 103/232 (44%), Gaps = 38/232 (16%)
Query: 926 RAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSG 985
R + + +L A+KR+ E++ + +++ K ++E+ E + + EL
Sbjct: 800 RGQIARRVYRQLLAEKREQEEKKKQEEEE---------KKKREEEERERERERREAELRA 850
Query: 986 LDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKL 1045
E + +E +ALQ++ ++A + E+ K N + +LE+++EDL+ EQ+
Sbjct: 851 QQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQ--- 907
Query: 1046 RVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQF 1105
+L L + S+ L+ ++ D+ L++ + E C + E L F
Sbjct: 908 -------------ELSLTEASLQKLQ---ERRDQELRRLEEEAC----RAAQEFLESLNF 947
Query: 1106 QKKIKELQARIE---ELEEEIEAERATRAKTEKQRSDYAREL--EELSERLE 1152
+I E IE + E +E A A EK ++++ EE+ E E
Sbjct: 948 D-EIDECVRNIERSLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFE 998
Score = 43.5 bits (101), Expect = 0.002
Identities = 36/145 (24%), Positives = 70/145 (48%), Gaps = 8/145 (5%)
Query: 1104 QFQKKIKELQARIEELEEEIEAERATR-AKTEKQRSDYAR---ELEELSERLEEAGGVTS 1159
Q +KK +E + + + EEE E ER R A+ Q+ + R ELE L + +EA
Sbjct: 818 QEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRE 877
Query: 1160 TQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLE 1219
+ + K+ E L+L +++E+ E +L + + E +Q L+R++++
Sbjct: 878 LEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQ--ELRRLEEEAC 935
Query: 1220 KEKSEF--KLEIDDLSSSMESVSKS 1242
+ EF L D++ + ++ +S
Sbjct: 936 RAAQEFLESLNFDEIDECVRNIERS 960
Score = 38.1 bits (87), Expect = 0.084
Identities = 29/113 (25%), Positives = 54/113 (47%), Gaps = 9/113 (7%)
Query: 1817 ETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKV 1876
E R +E + + E E+KK E + R+ ERR EL Q EE+ R Q ++ LQ
Sbjct: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE----TRKQQELEALQKSQ 869
Query: 1877 KSYKRQAEEADEQANAHLTKFRKAQHELEE-----AEERADIAESQVNKLRAK 1924
K + E ++ N + + + + E+E+ ++ + E+ + KL+ +
Sbjct: 870 KEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQER 922
Score = 37.7 bits (86), Expect = 0.11
Identities = 52/238 (21%), Positives = 101/238 (42%), Gaps = 53/238 (22%)
Query: 1254 EDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQT 1313
E + E + K EE + + + E E R+ E +E+
Sbjct: 814 EKREQEEKKKQEE-----------EEKKKREEEERERERERREA---------------- 846
Query: 1314 EELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWR 1373
EL+ Q EEE + + L ALQ S+ + +L RE ++++ + E L K ++ + +
Sbjct: 847 -ELRAQQEEETRKQQEL-EALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMK 904
Query: 1374 TKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQ-GEVEDLMVD 1432
+ E + + L++ +++ Q L+ EE+ C + ++ + L E+++ + +
Sbjct: 905 EQQELSLTEAS--LQKLQERRDQELRRLEEEA------CRAAQEFLESLNFDEIDECVRN 956
Query: 1433 VERANSLAAALDKKQRNFDKVLAEWKTKCEE------SQAELEASLKESRSLSTELFK 1484
+ER+ S+ + F LAE + CEE SQ E + E + FK
Sbjct: 957 IERSLSVGS-------EFSSELAE--SACEEKPNFNFSQPYPEEEVDEGFEADDDAFK 1005
Score = 37.0 bits (84), Expect = 0.19
Identities = 38/153 (24%), Positives = 71/153 (46%), Gaps = 20/153 (13%)
Query: 1444 DKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVK-RE 1502
+KK+R + E + + E +AEL A +E EL L+ + +EA E K +E
Sbjct: 828 EKKKREEE----ERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKE 883
Query: 1503 NKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRI 1562
NK + E+I K I +L++ ++Q EL + L + E + ++ R+
Sbjct: 884 NKQV--------EEILRLEKEIEDLQRMKEQQELSLTEASL-----QKLQERRDQELRRL 930
Query: 1563 QLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTV 1595
+ E + E + +EI++ RN +R++
Sbjct: 931 EEEACRAAQEFLESL--NFDEIDECVRNIERSL 961
Score = 35.4 bits (80), Expect = 0.55
Identities = 33/152 (21%), Positives = 68/152 (44%), Gaps = 10/152 (6%)
Query: 1484 KLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQI----ELEKA 1539
K + E+ + E +RE + E E+ E+ + + L+KS+K+ ELEK
Sbjct: 822 KKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQ 881
Query: 1540 DIQLALEE-AEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETM 1598
+EE E E+ + ++ Q EL+ ++ + + +D+E+ +L+ R +
Sbjct: 882 KENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEF 941
Query: 1599 QSAL-----DAEVRSRNEAIRLKKKMEGDLNE 1625
+L D VR+ ++ + + +L E
Sbjct: 942 LESLNFDEIDECVRNIERSLSVGSEFSSELAE 973
Score = 34.7 bits (78), Expect = 0.93
Identities = 46/176 (26%), Positives = 83/176 (47%), Gaps = 33/176 (18%)
Query: 1656 LHLDDA-LRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERV 1714
LHL A + Q+ L+ Q+A R L AE E +Q E +K E+E
Sbjct: 786 LHLKKAAIVFQKQLRGQIA--RRVYRQLLAEKREQEEKKKQEEEEKKKREEE-------- 835
Query: 1715 QLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQ 1774
+++ E +L+++ E+ +R + E +A + A + EL+K++
Sbjct: 836 -----------ERERERERREAELRAQQEEETR--KQQELEALQKSQKEAELTRELEKQK 882
Query: 1775 DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETR----IRELEFE 1826
+ E ++ LE+ ++DLQ R+ E ++L+L + +QKL+ R +R LE E
Sbjct: 883 ENKQVEEILR--LEKEIEDLQ-RMKEQQELSLT--EASLQKLQERRDQELRRLEEE 933
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.340
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,480,406
Number of Sequences: 37866
Number of extensions: 2903312
Number of successful extensions: 60580
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 778
Number of HSP's successfully gapped in prelim test: 1588
Number of HSP's that attempted gapping in prelim test: 13041
Number of HSP's gapped (non-prelim): 15630
length of query: 1940
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1823
effective length of database: 13,817,196
effective search space: 25188748308
effective search space used: 25188748308
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.