Search of human proteins with 95147551

Search of human proteins with 95147551

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|95147551 kynurenine aminotransferase I isoform a [Homo
sapiens]
         (422 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169881279 kynurenine aminotransferase I isoform a [Homo sapiens]   872   0.0  
gi|95147551 kynurenine aminotransferase I isoform a [Homo sapiens]    872   0.0  
gi|169881281 kynurenine aminotransferase I isoform b [Homo sapiens]   749   0.0  
gi|56713254 kynurenine aminotransferase III isoform 1 [Homo sapi...   466   e-131
gi|56713256 kynurenine aminotransferase III isoform 2 [Homo sapi...   466   e-131
gi|4507369 tyrosine aminotransferase [Homo sapiens]                    84   2e-16
gi|187936925 1-aminocyclopropane-1-carboxylate synthase homolog ...    52   8e-07
gi|14211921 1-aminocyclopropane-1-carboxylate synthase homolog [...    52   8e-07
gi|149944424 1-aminocyclopropane-1-carboxylate synthase homolog ...    51   2e-06
gi|7705897 kynurenine aminotransferase II [Homo sapiens]               47   2e-05
gi|33469970 kynurenine aminotransferase II [Homo sapiens]              47   2e-05
gi|4885351 glutamic pyruvate transaminase [Homo sapiens]               42   0.001
gi|215599424 glutamic pyruvate transaminase 2 isoform 2 [Homo sa...    38   0.020
gi|19263340 glutamic pyruvate transaminase 2 isoform 1 [Homo sap...    38   0.020
gi|170932526 nuclear receptor coactivator 7 isoform 2 [Homo sapi...    30   3.2  
gi|21361334 cystathionase isoform 1 [Homo sapiens]                     29   9.2  
gi|167466276 protein phosphatase 1K (PP2C domain containing) [Ho...    29   9.2  

>gi|169881279 kynurenine aminotransferase I isoform a [Homo sapiens]
          Length = 422

 Score =  872 bits (2252), Expect = 0.0
 Identities = 422/422 (100%), Positives = 422/422 (100%)

Query: 1   MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML 60
           MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML
Sbjct: 1   MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML 60

Query: 61  NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII 120
           NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII
Sbjct: 61  NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII 120

Query: 121 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL 180
           IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL
Sbjct: 121 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL 180

Query: 181 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL 240
           NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL
Sbjct: 181 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL 240

Query: 241 TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR 300
           TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR
Sbjct: 241 TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR 300

Query: 301 QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE 360
           QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE
Sbjct: 301 QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE 360

Query: 361 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV 420
           PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV
Sbjct: 361 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV 420

Query: 421 EL 422
           EL
Sbjct: 421 EL 422


>gi|95147551 kynurenine aminotransferase I isoform a [Homo sapiens]
          Length = 422

 Score =  872 bits (2252), Expect = 0.0
 Identities = 422/422 (100%), Positives = 422/422 (100%)

Query: 1   MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML 60
           MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML
Sbjct: 1   MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML 60

Query: 61  NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII 120
           NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII
Sbjct: 61  NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII 120

Query: 121 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL 180
           IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL
Sbjct: 121 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL 180

Query: 181 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL 240
           NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL
Sbjct: 181 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL 240

Query: 241 TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR 300
           TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR
Sbjct: 241 TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR 300

Query: 301 QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE 360
           QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE
Sbjct: 301 QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE 360

Query: 361 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV 420
           PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV
Sbjct: 361 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV 420

Query: 421 EL 422
           EL
Sbjct: 421 EL 422


>gi|169881281 kynurenine aminotransferase I isoform b [Homo sapiens]
          Length = 372

 Score =  749 bits (1935), Expect = 0.0
 Identities = 372/422 (88%), Positives = 372/422 (88%), Gaps = 50/422 (11%)

Query: 1   MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML 60
           MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML
Sbjct: 1   MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML 60

Query: 61  NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII 120
           NQYTKTF                                                  VII
Sbjct: 61  NQYTKTF--------------------------------------------------VII 70

Query: 121 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL 180
           IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL
Sbjct: 71  IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL 130

Query: 181 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL 240
           NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL
Sbjct: 131 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL 190

Query: 241 TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR 300
           TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR
Sbjct: 191 TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR 250

Query: 301 QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE 360
           QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE
Sbjct: 251 QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE 310

Query: 361 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV 420
           PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV
Sbjct: 311 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV 370

Query: 421 EL 422
           EL
Sbjct: 371 EL 372


>gi|56713254 kynurenine aminotransferase III isoform 1 [Homo
           sapiens]
          Length = 454

 Score =  466 bits (1199), Expect = e-131
 Identities = 216/419 (51%), Positives = 301/419 (71%), Gaps = 4/419 (0%)

Query: 3   KQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQ 62
           K   A+R++G+D N W+EF KLA++  VVNLGQGFPD  PP +  E      + D  LNQ
Sbjct: 38  KFTNAKRIEGLDSNVWIEFTKLAADPSVVNLGQGFPDISPPTYVKEELSKIAAID-SLNQ 96

Query: 63  YTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIE 122
           YT+ FG+P L K L+  + +L  ++ID  + +LVTVG YG+LF   QAL+DEGDEVI+I 
Sbjct: 97  YTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIV 156

Query: 123 PFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNT 182
           PF+DCYEPM  MAG  PVF+ L+  P+  G+  SSS+W LDP EL  KF S+TKA++LNT
Sbjct: 157 PFYDCYEPMVRMAGATPVFIPLRSKPVY-GKRWSSSDWTLDPQELESKFNSKTKAIILNT 215

Query: 183 PNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTI 242
           P+NPLGKV++REEL+++A LC ++D +CI+DEVY+W+VY G++H+ IA+ PGMWERT+TI
Sbjct: 216 PHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITI 275

Query: 243 GSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQP 302
           GSAGKTFS TGWK+GW +GP+H++KHL+TV QN+++ C T  Q A+A++F  +      P
Sbjct: 276 GSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFWIDIKRMDDP 335

Query: 303 SSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPY 362
             YF   P+ ++  RD M+R L+SVGLKPI+P G YF+I D+S     + D+    +EPY
Sbjct: 336 ECYFNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFIIADVSLLDPDLSDMKN--NEPY 393

Query: 363 DRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVE 421
           D +FVKWM K+K L AIPVS F +   +  F+ ++RFCF+K ++TL A +E ++ W V+
Sbjct: 394 DYKFVKWMTKHKKLSAIPVSAFCNSETKSQFEKFVRFCFIKKDSTLDAAEEIIKAWSVQ 452


>gi|56713256 kynurenine aminotransferase III isoform 2 [Homo
           sapiens]
          Length = 420

 Score =  466 bits (1199), Expect = e-131
 Identities = 216/419 (51%), Positives = 301/419 (71%), Gaps = 4/419 (0%)

Query: 3   KQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQ 62
           K   A+R++G+D N W+EF KLA++  VVNLGQGFPD  PP +  E      + D  LNQ
Sbjct: 4   KFTNAKRIEGLDSNVWIEFTKLAADPSVVNLGQGFPDISPPTYVKEELSKIAAID-SLNQ 62

Query: 63  YTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIE 122
           YT+ FG+P L K L+  + +L  ++ID  + +LVTVG YG+LF   QAL+DEGDEVI+I 
Sbjct: 63  YTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIV 122

Query: 123 PFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNT 182
           PF+DCYEPM  MAG  PVF+ L+  P+  G+  SSS+W LDP EL  KF S+TKA++LNT
Sbjct: 123 PFYDCYEPMVRMAGATPVFIPLRSKPVY-GKRWSSSDWTLDPQELESKFNSKTKAIILNT 181

Query: 183 PNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTI 242
           P+NPLGKV++REEL+++A LC ++D +CI+DEVY+W+VY G++H+ IA+ PGMWERT+TI
Sbjct: 182 PHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITI 241

Query: 243 GSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQP 302
           GSAGKTFS TGWK+GW +GP+H++KHL+TV QN+++ C T  Q A+A++F  +      P
Sbjct: 242 GSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFWIDIKRMDDP 301

Query: 303 SSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPY 362
             YF   P+ ++  RD M+R L+SVGLKPI+P G YF+I D+S     + D+    +EPY
Sbjct: 302 ECYFNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFIIADVSLLDPDLSDMKN--NEPY 359

Query: 363 DRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVE 421
           D +FVKWM K+K L AIPVS F +   +  F+ ++RFCF+K ++TL A +E ++ W V+
Sbjct: 360 DYKFVKWMTKHKKLSAIPVSAFCNSETKSQFEKFVRFCFIKKDSTLDAAEEIIKAWSVQ 418


>gi|4507369 tyrosine aminotransferase [Homo sapiens]
          Length = 454

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 79/357 (22%), Positives = 155/357 (43%), Gaps = 39/357 (10%)

Query: 37  FPDFPPPDFAVEAFQHAV-SGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVL 95
           F + P      +A + A+ SG +  N Y  + G+    + +AS++     +     ++V+
Sbjct: 84  FGNLPTDPEVTQAMKDALDSGKY--NGYAPSIGFLSSREEIASYYH--CPEAPLEAKDVI 139

Query: 96  VTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELG 155
           +T G   A+      L + G  +++  P F  Y+ +    G      +L P         
Sbjct: 140 LTSGCSQAIDLCLAVLANPGQNILVPRPGFSLYKTLAESMGIEVKLYNLLP--------- 190

Query: 156 SSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEV 215
              +W++D  +L      +T  L++N P+NP G VFS+  L+ + ++  +  V  + DE+
Sbjct: 191 -EKSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILADEI 249

Query: 216 YQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPD-------HIMKH 268
           Y  MV+   ++  +A+L       L+ G   K +   GW++GW+L  D        I   
Sbjct: 250 YGDMVFSDCKYEPLATL-STDVPILSCGGLAKRWLVPGWRLGWILIHDRRDIFGNEIRDG 308

Query: 269 LRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSV- 327
           L  + Q  +  C T  Q A+      + +L R P  ++      ++   D    +L ++ 
Sbjct: 309 LVKLSQRILGPC-TIVQGAL------KSILCRTPGEFYHNTLSFLKSNADLCYGALAAIP 361

Query: 328 GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIF 384
           GL+P+ P G+ +L+  I     +M   P   +   D  F + ++  + +  +P + F
Sbjct: 362 GLRPVRPSGAMYLMVGI-----EMEHFP---EFENDVEFTERLVAEQSVHCLPATCF 410


>gi|187936925 1-aminocyclopropane-1-carboxylate synthase homolog
           [Homo sapiens]
          Length = 501

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 59/210 (28%), Positives = 97/210 (46%), Gaps = 17/210 (8%)

Query: 60  LNQYTKTFGYPPLTKILASFFGELLGQEIDPLR--NVLVTVGGYGALFTAFQALVDEGDE 117
           L QY    G+  L + +A F        + PLR  NV+V  GG  +LF+A   ++ E  E
Sbjct: 129 LLQYADWRGHLFLREEVAKFLSFYCKSPV-PLRPENVVVLNGG-ASLFSALATVLCEAGE 186

Query: 118 VIIIE-PFFDCYEPMTMMAGG-RPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTS-- 173
             +I  P++        + G  R  +V L       G         ++ +E+A +     
Sbjct: 187 AFLIPTPYYGAITQHVCLYGNIRLAYVYLDSEV--TGLDTRPFQLTVEKLEMALREAHSE 244

Query: 174 --RTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYD---GHQHI- 227
             + K L+L +P NPLG V+S EEL+      ++H +  I DEVY   V++   G++ + 
Sbjct: 245 GVKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEKSVGYRSVL 304

Query: 228 SIASLPGMWERTLTIGSAGKTFSATGWKVG 257
           S+  LP   +RT  + +  K F  +G + G
Sbjct: 305 SLERLPDP-QRTHVMWATSKDFGMSGLRFG 333


>gi|14211921 1-aminocyclopropane-1-carboxylate synthase homolog
           [Homo sapiens]
          Length = 501

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 59/210 (28%), Positives = 97/210 (46%), Gaps = 17/210 (8%)

Query: 60  LNQYTKTFGYPPLTKILASFFGELLGQEIDPLR--NVLVTVGGYGALFTAFQALVDEGDE 117
           L QY    G+  L + +A F        + PLR  NV+V  GG  +LF+A   ++ E  E
Sbjct: 129 LLQYADWRGHLFLREEVAKFLSFYCKSPV-PLRPENVVVLNGG-ASLFSALATVLCEAGE 186

Query: 118 VIIIE-PFFDCYEPMTMMAGG-RPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTS-- 173
             +I  P++        + G  R  +V L       G         ++ +E+A +     
Sbjct: 187 AFLIPTPYYGAITQHVCLYGNIRLAYVYLDSEV--TGLDTRPFQLTVEKLEMALREAHSE 244

Query: 174 --RTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYD---GHQHI- 227
             + K L+L +P NPLG V+S EEL+      ++H +  I DEVY   V++   G++ + 
Sbjct: 245 GVKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEKSVGYRSVL 304

Query: 228 SIASLPGMWERTLTIGSAGKTFSATGWKVG 257
           S+  LP   +RT  + +  K F  +G + G
Sbjct: 305 SLERLPDP-QRTHVMWATSKDFGMSGLRFG 333


>gi|149944424 1-aminocyclopropane-1-carboxylate synthase homolog
           (Arabidopsis)(non-functional)-like [Homo sapiens]
          Length = 568

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 57/214 (26%), Positives = 94/214 (43%), Gaps = 25/214 (11%)

Query: 60  LNQYTKTFGYPPLTKILASFFGELLGQ--EIDPLRNVLVTVGGYGALFTAFQALVDEGDE 117
           L QY    G P L + +A F          +DP  NV+V  G           L D G+ 
Sbjct: 201 LLQYPDWRGQPFLREEVARFLTYYCRAPTRLDP-ENVVVLNGCCSVFCALAMVLCDPGEA 259

Query: 118 VIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSN-WQL--DPME-------L 167
            ++  PF+  +   + +       V L P  +++    ++++ +QL  D +E       L
Sbjct: 260 FLVPAPFYGGFAFSSRLYAK----VELIPVHLESEVTVTNTHPFQLTVDKLEEALLEARL 315

Query: 168 AGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDG---- 223
            GK   + + LVL  P NPLG ++S + L       +++++  I DE+Y   V+D     
Sbjct: 316 EGK---KVRGLVLINPQNPLGDIYSPDSLMKYLEFAKRYNLHVIIDEIYMLSVFDESITF 372

Query: 224 HQHISIASLPGMWERTLTIGSAGKTFSATGWKVG 257
           H  +S+ SLP    RT  I    K F  +G++ G
Sbjct: 373 HSILSMKSLPDS-NRTHVIWGTSKDFGISGFRFG 405


>gi|7705897 kynurenine aminotransferase II [Homo sapiens]
          Length = 425

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 44/199 (22%), Positives = 91/199 (45%), Gaps = 4/199 (2%)

Query: 93  NVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFV-SLKPGPIQN 151
           ++ VT G    L   F+ +++ GD V++ EP +          G   + V S + G + +
Sbjct: 110 DLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPD 169

Query: 152 GELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCI 211
                 S W+ +  +   K T +    V N  NNP G   + E  + +  L +++D + I
Sbjct: 170 SLRDILSRWKPEDAKNPQKNTPKFLYTVPNG-NNPTGNSLTSERKKEIYELARKYDFLII 228

Query: 212 TDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRT 271
            D+ Y ++ ++  +  +  S+  +  R +   S  K  S+ G ++G++ GP  +++ +  
Sbjct: 229 EDDPYYFLQFNKFRVPTFLSMD-VDGRVIRADSFSKIISS-GLRIGFLTGPKPLIERVIL 286

Query: 272 VHQNSVFHCPTQSQAAVAE 290
             Q S  H  T +Q  +++
Sbjct: 287 HIQVSTLHPSTFNQLMISQ 305


>gi|33469970 kynurenine aminotransferase II [Homo sapiens]
          Length = 425

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 44/199 (22%), Positives = 91/199 (45%), Gaps = 4/199 (2%)

Query: 93  NVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFV-SLKPGPIQN 151
           ++ VT G    L   F+ +++ GD V++ EP +          G   + V S + G + +
Sbjct: 110 DLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPD 169

Query: 152 GELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCI 211
                 S W+ +  +   K T +    V N  NNP G   + E  + +  L +++D + I
Sbjct: 170 SLRDILSRWKPEDAKNPQKNTPKFLYTVPNG-NNPTGNSLTSERKKEIYELARKYDFLII 228

Query: 212 TDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRT 271
            D+ Y ++ ++  +  +  S+  +  R +   S  K  S+ G ++G++ GP  +++ +  
Sbjct: 229 EDDPYYFLQFNKFRVPTFLSMD-VDGRVIRADSFSKIISS-GLRIGFLTGPKPLIERVIL 286

Query: 272 VHQNSVFHCPTQSQAAVAE 290
             Q S  H  T +Q  +++
Sbjct: 287 HIQVSTLHPSTFNQLMISQ 305


>gi|4885351 glutamic pyruvate transaminase [Homo sapiens]
          Length = 496

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 50/193 (25%), Positives = 75/193 (38%), Gaps = 24/193 (12%)

Query: 43  PDFAVEAFQHA-----VSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVT 97
           P+F  +A + A       G   L  Y+ + G   + + +A +     G       NV ++
Sbjct: 98  PNFPDDAKKRAERILQACGGHSLGAYSVSSGIQLIREDVARYIERRDGGIPADPNNVFLS 157

Query: 98  VGGYGALFTAFQALV-DEGDE---VIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGE 153
            G   A+ T  + LV  EG     V+I  P +  Y       G   V          +  
Sbjct: 158 TGASDAIVTVLKLLVAGEGHTRTGVLIPIPQYPLYSATLAELGAVQV----------DYY 207

Query: 154 LGSSSNWQLDPMEL-----AGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDV 208
           L     W LD  EL       +   R +AL +  P NP G+V +RE +E V     +  +
Sbjct: 208 LDEERAWALDVAELHRALGQARDHCRPRALCVINPGNPTGQVQTRECIEAVIRFAFEERL 267

Query: 209 VCITDEVYQWMVY 221
             + DEVYQ  VY
Sbjct: 268 FLLADEVYQDNVY 280


>gi|215599424 glutamic pyruvate transaminase 2 isoform 2 [Homo
           sapiens]
          Length = 423

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 47/193 (24%), Positives = 73/193 (37%), Gaps = 24/193 (12%)

Query: 43  PDFAVEAFQHA-----VSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVT 97
           P F  +A + A       G   L  Y+ + G   + + +A++     G       N+ +T
Sbjct: 25  PSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDNIYLT 84

Query: 98  VGGYGALFTAFQALVDEGDE----VIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGE 153
            G    + T  + LV  G +    V+I  P +  Y  +        V          N  
Sbjct: 85  TGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQV----------NYY 134

Query: 154 LGSSSNWQLDPMELA-----GKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDV 208
           L   + W L+  EL       K     K L +  P NP G+V SR+ +E V     +  +
Sbjct: 135 LDEENCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKL 194

Query: 209 VCITDEVYQWMVY 221
             + DEVYQ  VY
Sbjct: 195 FLLADEVYQDNVY 207


>gi|19263340 glutamic pyruvate transaminase 2 isoform 1 [Homo
           sapiens]
          Length = 523

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 47/193 (24%), Positives = 73/193 (37%), Gaps = 24/193 (12%)

Query: 43  PDFAVEAFQHA-----VSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVT 97
           P F  +A + A       G   L  Y+ + G   + + +A++     G       N+ +T
Sbjct: 125 PSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDNIYLT 184

Query: 98  VGGYGALFTAFQALVDEGDE----VIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGE 153
            G    + T  + LV  G +    V+I  P +  Y  +        V          N  
Sbjct: 185 TGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQV----------NYY 234

Query: 154 LGSSSNWQLDPMELA-----GKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDV 208
           L   + W L+  EL       K     K L +  P NP G+V SR+ +E V     +  +
Sbjct: 235 LDEENCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKL 294

Query: 209 VCITDEVYQWMVY 221
             + DEVYQ  VY
Sbjct: 295 FLLADEVYQDNVY 307


>gi|170932526 nuclear receptor coactivator 7 isoform 2 [Homo
           sapiens]
          Length = 931

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 16/63 (25%), Positives = 33/63 (52%), Gaps = 4/63 (6%)

Query: 178 LVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASL---PG 234
           +++ TPNN +      + L ++ + C+++ ++C  +EV    +Y+   H+ I      PG
Sbjct: 239 VMIVTPNNIMFDPHKSDPL-VIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSPG 297

Query: 235 MWE 237
            WE
Sbjct: 298 EWE 300


>gi|21361334 cystathionase isoform 1 [Homo sapiens]
          Length = 405

 Score = 28.9 bits (63), Expect = 9.2
 Identities = 22/92 (23%), Positives = 39/92 (42%), Gaps = 19/92 (20%)

Query: 167 LAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQH-DVVCITDEVYQWMVYDGHQ 225
           L    T  TK + + TP NP  KV    ++E  A +  +H D++ + D  +         
Sbjct: 143 LEAAITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHGDIILVVDNTF--------- 190

Query: 226 HISIASLPGMWERTLTIGSAGKTFSATGWKVG 257
                 +   ++R L +G+    +SAT +  G
Sbjct: 191 ------MSPYFQRPLALGADISMYSATKYMNG 216


>gi|167466276 protein phosphatase 1K (PP2C domain containing) [Homo
           sapiens]
          Length = 372

 Score = 28.9 bits (63), Expect = 9.2
 Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 14/79 (17%)

Query: 155 GSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQ---------Q 205
           GS + W     +  G + +R    +L  P+   GK   +  LE V    Q         +
Sbjct: 56  GSPATW-----DNFGIWDNRIDEPILLPPSIKYGKPIPKISLENVGCASQIGKRKENEDR 110

Query: 206 HDVVCITDEVYQWMVYDGH 224
            D   +TDEV  + VYDGH
Sbjct: 111 FDFAQLTDEVLYFAVYDGH 129


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,323,622
Number of Sequences: 37866
Number of extensions: 795978
Number of successful extensions: 1490
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1469
Number of HSP's gapped (non-prelim): 18
length of query: 422
length of database: 18,247,518
effective HSP length: 105
effective length of query: 317
effective length of database: 14,271,588
effective search space: 4524093396
effective search space used: 4524093396
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.