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Search of human proteins with 94721253
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo
sapiens]
(759 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo s... 1478 0.0
gi|94721255 solute carrier family 26, member 6 isoform 2 [Homo s... 1471 0.0
gi|94721259 solute carrier family 26, member 6 isoform 4 [Homo s... 1439 0.0
gi|94721257 solute carrier family 26, member 6 isoform 3 [Homo s... 1407 0.0
gi|39752683 prestin isoform a [Homo sapiens] 560 e-159
gi|4505697 pendrin [Homo sapiens] 550 e-156
gi|45827800 prestin isoform b [Homo sapiens] 540 e-153
gi|16418413 solute carrier family 26, member 9 isoform a [Homo s... 504 e-142
gi|217272867 solute carrier family 26, member 9 isoform b [Homo ... 504 e-142
gi|4557535 solute carrier family 26, member 3 [Homo sapiens] 499 e-141
gi|45827802 prestin isoform c [Homo sapiens] 450 e-126
gi|47131207 solute carrier family 26, member 1 isoform a [Homo s... 405 e-113
gi|20336272 solute carrier family 26, member 1 isoform a [Homo s... 405 e-113
gi|100913030 solute carrier family 26 member 2 [Homo sapiens] 404 e-112
gi|16418457 solute carrier family 26, member 8 isoform a [Homo s... 373 e-103
gi|16306483 solute carrier family 26, member 7 isoform a [Homo s... 307 2e-83
gi|20336282 solute carrier family 26, member 7 isoform b [Homo s... 307 2e-83
gi|65506789 solute carrier family 26, member 10 [Homo sapiens] 279 8e-75
gi|217272870 solute carrier family 26, member 9 isoform c [Homo ... 259 5e-69
gi|45827804 prestin isoform d [Homo sapiens] 248 1e-65
gi|20336285 solute carrier family 26, member 8 isoform b [Homo s... 234 2e-61
gi|85540447 solute carrier family 26, member 11 [Homo sapiens] 226 6e-59
gi|20336274 solute carrier family 26, member 1 isoform b [Homo s... 115 2e-25
gi|116256458 hypothetical protein LOC121053 [Homo sapiens] 35 0.34
gi|62422577 neurobeachin [Homo sapiens] 33 1.3
gi|40068059 CBF1 interacting corepressor [Homo sapiens] 32 1.7
gi|55749531 splicing factor 3B subunit 2 [Homo sapiens] 32 1.7
gi|157649069 ATPase, aminophospholipid transporter (APLT), class... 32 2.2
gi|17978471 ATPase, aminophospholipid transporter (APLT), class ... 32 2.2
gi|45827729 scribble isoform b [Homo sapiens] 32 2.2
>gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo
sapiens]
Length = 759
Score = 1478 bits (3826), Expect = 0.0
Identities = 759/759 (100%), Positives = 759/759 (100%)
Query: 1 MGLADASGPRDTQALLSATQAMDLRRRDYHMERPLLNQEHLEELGRWGSAPRTHQWRTWL 60
MGLADASGPRDTQALLSATQAMDLRRRDYHMERPLLNQEHLEELGRWGSAPRTHQWRTWL
Sbjct: 1 MGLADASGPRDTQALLSATQAMDLRRRDYHMERPLLNQEHLEELGRWGSAPRTHQWRTWL 60
Query: 61 QCSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPV 120
QCSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPV
Sbjct: 61 QCSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPV 120
Query: 121 FGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALNDSMINETARDAAR 180
FGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALNDSMINETARDAAR
Sbjct: 121 FGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALNDSMINETARDAAR 180
Query: 181 VQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLS 240
VQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLS
Sbjct: 181 VQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLS 240
Query: 241 SHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELL 300
SHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELL
Sbjct: 241 SHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELL 300
Query: 301 TLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAI 360
TLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAI
Sbjct: 301 TLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAI 360
Query: 361 SLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGA 420
SLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGA
Sbjct: 361 SLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGA 420
Query: 421 ISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVT 480
ISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVT
Sbjct: 421 ISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVT 480
Query: 481 FTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGV 540
FTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGV
Sbjct: 481 FTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGV 540
Query: 541 KVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQ 600
KVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQ
Sbjct: 541 KVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQ 600
Query: 601 AASPKGASVSINVNTSLEDMRSNNVEDCKMMQVSSGDKMEDATANGQEDSKAPDGSTLKA 660
AASPKGASVSINVNTSLEDMRSNNVEDCKMMQVSSGDKMEDATANGQEDSKAPDGSTLKA
Sbjct: 601 AASPKGASVSINVNTSLEDMRSNNVEDCKMMQVSSGDKMEDATANGQEDSKAPDGSTLKA 660
Query: 661 LGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGH 720
LGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGH
Sbjct: 661 LGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGH 720
Query: 721 FFDASITKKHLFASVHDAVTFALQHPRPVPDSPVSVTRL 759
FFDASITKKHLFASVHDAVTFALQHPRPVPDSPVSVTRL
Sbjct: 721 FFDASITKKHLFASVHDAVTFALQHPRPVPDSPVSVTRL 759
>gi|94721255 solute carrier family 26, member 6 isoform 2 [Homo
sapiens]
Length = 758
Score = 1471 bits (3809), Expect = 0.0
Identities = 758/759 (99%), Positives = 758/759 (99%), Gaps = 1/759 (0%)
Query: 1 MGLADASGPRDTQALLSATQAMDLRRRDYHMERPLLNQEHLEELGRWGSAPRTHQWRTWL 60
MGLADASGPRDTQALLSATQAMDLRRRDYHMERPLLNQEHLEELGRWGSAPRTHQWRTWL
Sbjct: 1 MGLADASGPRDTQALLSATQAMDLRRRDYHMERPLLNQEHLEELGRWGSAPRTHQWRTWL 60
Query: 61 QCSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPV 120
QCSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPV
Sbjct: 61 QCSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPV 120
Query: 121 FGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALNDSMINETARDAAR 180
FGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALNDSMINETARDAAR
Sbjct: 121 FGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALNDSMINETARDAAR 180
Query: 181 VQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLS 240
VQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLS
Sbjct: 181 VQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLS 240
Query: 241 SHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELL 300
SHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELL
Sbjct: 241 SHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELL 300
Query: 301 TLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAI 360
TLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAI
Sbjct: 301 TLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAI 360
Query: 361 SLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGA 420
SLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGA
Sbjct: 361 SLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGA 420
Query: 421 ISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVT 480
ISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVT
Sbjct: 421 ISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVT 480
Query: 481 FTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGV 540
FTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGV
Sbjct: 481 FTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGV 540
Query: 541 KVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQ 600
KVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQ
Sbjct: 541 KVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQ 600
Query: 601 AASPKGASVSINVNTSLEDMRSNNVEDCKMMQVSSGDKMEDATANGQEDSKAPDGSTLKA 660
AASPKGASVSINVNTSLEDMRSNNVEDCKMM VSSGDKMEDATANGQEDSKAPDGSTLKA
Sbjct: 601 AASPKGASVSINVNTSLEDMRSNNVEDCKMM-VSSGDKMEDATANGQEDSKAPDGSTLKA 659
Query: 661 LGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGH 720
LGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGH
Sbjct: 660 LGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGH 719
Query: 721 FFDASITKKHLFASVHDAVTFALQHPRPVPDSPVSVTRL 759
FFDASITKKHLFASVHDAVTFALQHPRPVPDSPVSVTRL
Sbjct: 720 FFDASITKKHLFASVHDAVTFALQHPRPVPDSPVSVTRL 758
>gi|94721259 solute carrier family 26, member 6 isoform 4 [Homo
sapiens]
Length = 738
Score = 1439 bits (3725), Expect = 0.0
Identities = 738/738 (100%), Positives = 738/738 (100%)
Query: 22 MDLRRRDYHMERPLLNQEHLEELGRWGSAPRTHQWRTWLQCSRARAYALLLQHLPVLVWL 81
MDLRRRDYHMERPLLNQEHLEELGRWGSAPRTHQWRTWLQCSRARAYALLLQHLPVLVWL
Sbjct: 1 MDLRRRDYHMERPLLNQEHLEELGRWGSAPRTHQWRTWLQCSRARAYALLLQHLPVLVWL 60
Query: 82 PRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFYPVFIYFLFGTSRH 141
PRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFYPVFIYFLFGTSRH
Sbjct: 61 PRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFYPVFIYFLFGTSRH 120
Query: 142 ISVGTFAVMSVMVGSVTESLAPQALNDSMINETARDAARVQVASTLSVLVGLFQVGLGLI 201
ISVGTFAVMSVMVGSVTESLAPQALNDSMINETARDAARVQVASTLSVLVGLFQVGLGLI
Sbjct: 121 ISVGTFAVMSVMVGSVTESLAPQALNDSMINETARDAARVQVASTLSVLVGLFQVGLGLI 180
Query: 202 HFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQ 261
HFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQ
Sbjct: 181 HFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQ 240
Query: 262 SKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVD 321
SKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVD
Sbjct: 241 SKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVD 300
Query: 322 VVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELV 381
VVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELV
Sbjct: 301 VVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELV 360
Query: 382 ALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLP 441
ALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLP
Sbjct: 361 ALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLP 420
Query: 442 KAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSL 501
KAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSL
Sbjct: 421 KAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSL 480
Query: 502 LLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDAL 561
LLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDAL
Sbjct: 481 LLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDAL 540
Query: 562 KQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDMR 621
KQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDMR
Sbjct: 541 KQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDMR 600
Query: 622 SNNVEDCKMMQVSSGDKMEDATANGQEDSKAPDGSTLKALGLPQPDFHSLILDLGALSFV 681
SNNVEDCKMMQVSSGDKMEDATANGQEDSKAPDGSTLKALGLPQPDFHSLILDLGALSFV
Sbjct: 601 SNNVEDCKMMQVSSGDKMEDATANGQEDSKAPDGSTLKALGLPQPDFHSLILDLGALSFV 660
Query: 682 DTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGHFFDASITKKHLFASVHDAVTF 741
DTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGHFFDASITKKHLFASVHDAVTF
Sbjct: 661 DTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGHFFDASITKKHLFASVHDAVTF 720
Query: 742 ALQHPRPVPDSPVSVTRL 759
ALQHPRPVPDSPVSVTRL
Sbjct: 721 ALQHPRPVPDSPVSVTRL 738
>gi|94721257 solute carrier family 26, member 6 isoform 3 [Homo
sapiens]
Length = 740
Score = 1407 bits (3642), Expect = 0.0
Identities = 730/759 (96%), Positives = 732/759 (96%), Gaps = 19/759 (2%)
Query: 1 MGLADASGPRDTQALLSATQAMDLRRRDYHMERPLLNQEHLEELGRWGSAPRTHQWRTWL 60
MGLADASGPRDTQALLSATQAMDLRRRDYHMERPLLNQEHLEELGRWGSAPRTHQWRTWL
Sbjct: 1 MGLADASGPRDTQALLSATQAMDLRRRDYHMERPLLNQEHLEELGRWGSAPRTHQWRTWL 60
Query: 61 QCSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPV 120
QCSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPV
Sbjct: 61 QCSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPV 120
Query: 121 FGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALNDSMINETARDAAR 180
FGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALNDSMINETARDAAR
Sbjct: 121 FGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALNDSMINETARDAAR 180
Query: 181 VQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLS 240
VQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLS
Sbjct: 181 VQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLS 240
Query: 241 SHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELL 300
SHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELL
Sbjct: 241 SHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELL 300
Query: 301 TLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAI 360
TLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAI
Sbjct: 301 TLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAI 360
Query: 361 SLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGA 420
SLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGA
Sbjct: 361 SLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGA 420
Query: 421 ISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVT 480
ISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVT
Sbjct: 421 ISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVT 480
Query: 481 FTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGV 540
FTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGV
Sbjct: 481 FTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGV 540
Query: 541 KVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQ 600
KVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQ
Sbjct: 541 KVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQ 600
Query: 601 AASPKGASVSINVNTSLEDMRSNNVEDCKMMQVSSGDKMEDATANGQEDSKAPDGSTLKA 660
A A ++ QVSSGDKMEDATANGQEDSKAPDGSTLKA
Sbjct: 601 AGPLLSACLA-------------------PQQVSSGDKMEDATANGQEDSKAPDGSTLKA 641
Query: 661 LGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGH 720
LGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGH
Sbjct: 642 LGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGH 701
Query: 721 FFDASITKKHLFASVHDAVTFALQHPRPVPDSPVSVTRL 759
FFDASITKKHLFASVHDAVTFALQHPRPVPDSPVSVTRL
Sbjct: 702 FFDASITKKHLFASVHDAVTFALQHPRPVPDSPVSVTRL 740
>gi|39752683 prestin isoform a [Homo sapiens]
Length = 744
Score = 560 bits (1442), Expect = e-159
Identities = 300/742 (40%), Positives = 456/742 (61%), Gaps = 57/742 (7%)
Query: 15 LLSATQAMDLRRRDYHMERPLLNQEHLEE-LGRWGSAPRT--HQWRTWLQCSRARAYALL 71
+L+ATQ Y++ERP+ + L+E L P + + + C+ + ++
Sbjct: 9 ILAATQR-------YYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNII 61
Query: 72 LQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFYPVF 131
LP+ WLP Y ++++LGDL+SG+S ++QLPQGLA+A+LA +PP+FGLYSSFYPV
Sbjct: 62 YMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVI 121
Query: 132 IYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALN-DSMINET----ARDAARVQVAST 186
+Y GTSRHIS+G FAV+S+M+G V L P + +N T ARDA RV+VA +
Sbjct: 122 MYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMS 181
Query: 187 LSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPL 246
+++L G+ Q LG+ FGFV YL+EPLVRG+TTAAAV VF S LKY+FG+ +SG
Sbjct: 182 VTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIF 241
Query: 247 SLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIGAT 306
S++Y+ + V + V ++ + +L+ K N++ +++LP PIP E ++ T
Sbjct: 242 SVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGT 301
Query: 307 GISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGKIF 366
GIS G LK + VDVVG +P GL+PP P+T LF + A IA+VGF++ IS+ K
Sbjct: 302 GISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTL 361
Query: 367 ALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLFI 426
A +HGY+VD NQEL+ALGL N IG +FQ F +SCS+SRSLVQE TGG +Q+AG ++SL I
Sbjct: 362 ANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMI 421
Query: 427 LLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATIL 486
LL+I+ G LF LP+AVL+AI+IVNLKGM Q SD+ W+ ++ +L IWL TF +++
Sbjct: 422 LLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLF 481
Query: 487 LNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFRSS 546
L LD GL+ AVI +LL V+ RTQ P Y VLG++P+TD+Y D+ Y E KE+ G+K+F+ +
Sbjct: 482 LGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQIN 541
Query: 547 ATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQAASPKG 606
A +Y+AN++ YS+ALK++ GV+ ++ ++K ++K
Sbjct: 542 APIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKY----------------------- 578
Query: 607 ASVSINVNTSLEDMRSNNVEDCKMMQVSSGDKMEDATANGQEDS---------KAPDGST 657
+++ + N+ + +++ + EDAT +ED K+
Sbjct: 579 ----------AKEVGNANMANATVVKADAEVDGEDATKPEEEDGEVKYPPIVIKSTFPEE 628
Query: 658 LKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLE 717
++ P + H++ILD ++F+D+V +K+L I ++ ++ + VY+A C + VV+ L
Sbjct: 629 MQRFMPPGDNVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLT 688
Query: 718 AGHFFDASITKKHLFASVHDAV 739
FF+ + LF S+HDAV
Sbjct: 689 RNRFFENPALWELLFHSIHDAV 710
>gi|4505697 pendrin [Homo sapiens]
Length = 780
Score = 550 bits (1416), Expect = e-156
Identities = 284/691 (41%), Positives = 438/691 (63%), Gaps = 29/691 (4%)
Query: 62 CSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVF 121
CSR RA+ +L +P+L WLP+Y V++WLL D++SG+S ++ QG+AYALLA +P +
Sbjct: 56 CSRKRAFGVLKTLVPILEWLPKYRVKEWLLSDVISGVSTGLVATLQGMAYALLAAVPVGY 115
Query: 122 GLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQ-----------ALNDSM 170
GLYS+F+P+ YF+FGTSRHISVG F V+S+MVGSV S+AP LN +M
Sbjct: 116 GLYSAFFPILTYFIFGTSRHISVGPFPVVSLMVGSVVLSMAPDEHFLVSSSNGTVLNTTM 175
Query: 171 INETARDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQ 230
I+ ARD ARV +AS L++LVG+ Q+ G + GF+V YL++PLV G+TTAAA QV VSQ
Sbjct: 176 IDTAARDTARVLIASALTLLVGIIQLIFGGLQIGFIVRYLADPLVGGFTTAAAFQVLVSQ 235
Query: 231 LKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQ 290
LK V + +++G LS+IYT++E+ + + + + VV + VK LND+ + +
Sbjct: 236 LKIVLNVSTKNYNGVLSIIYTLVEIFQNIGDTNLADFTAGLLTIVVCMAVKELNDRFRHK 295
Query: 291 LPMPIPGELLTLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFT 350
+P+PIP E++ I AT ISYG L+ + +V +IP G +PP P LFS+++ ++F+
Sbjct: 296 IPVPIPIEVIVTIIATAISYGANLEKNYNAGIVKSIPRGFLPPELPPVSLFSEMLAASFS 355
Query: 351 IAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQES 410
IAVV +AIA+S+GK++A ++ Y +D NQE +A G+SN+ G F CF + ++SR+ VQES
Sbjct: 356 IAVVAYAIAVSVGKVYATKYDYTIDGNQEFIAFGISNIFSGFFSCFVATTALSRTAVQES 415
Query: 411 TGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKAN 470
TGG +QVAG IS+ +++ I+ LG+L L K+VLAA++I NLKGM QL D+ LW+ N
Sbjct: 416 TGGKTQVAGIISAAIVMIAILALGKLLEPLQKSVLAAVVIANLKGMFMQLCDIPRLWRQN 475
Query: 471 RADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAE 530
+ D +IW+ T +I+L LDLGL+ +IF LL VV+R Q P ++ LG +P TDIY+
Sbjct: 476 KIDAVIWVFTCIVSIILGLDLGLLAGLIFGLLTVVLRVQFPSWNGLGSIPSTDIYKSTKN 535
Query: 531 YSEAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQ 590
Y +E +GVK+ R S+ +++ N + + +K G D + +++ K L+ K+++
Sbjct: 536 YKNIEEPQGVKILRFSSPIFYGNVDGFKKCIKSTVGFDAIRVYNKRLKALR-----KIQK 590
Query: 591 LQKEEKLRKQAASPKGASVSINVNTSLEDMRSNNVEDCKMMQVSSGDKMEDATANGQEDS 650
L K +LR + K +S V+T+ ++ED + + + + + N +
Sbjct: 591 LIKSGQLR----ATKNGIISDAVSTNNAFEPDEDIEDLEELDIPTKEIEIQVDWNSELPV 646
Query: 651 KAPDGSTLKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHS 710
K + +P+ HSL+LD GA+SF+D V ++SL+ I +F+ I+V VY A+
Sbjct: 647 K---------VNVPKVPIHSLVLDCGAISFLDVVGVRSLRVIVKEFQRIDVNVYFASLQD 697
Query: 711 PVVSQLEAGHFFDASITKKHLFASVHDAVTF 741
V+ +LE FFD +I K F +VHDA+ +
Sbjct: 698 YVIEKLEQCGFFDDNIRKDTFFLTVHDAILY 728
>gi|45827800 prestin isoform b [Homo sapiens]
Length = 685
Score = 540 bits (1391), Expect = e-153
Identities = 288/711 (40%), Positives = 439/711 (61%), Gaps = 57/711 (8%)
Query: 15 LLSATQAMDLRRRDYHMERPLLNQEHLEE-LGRWGSAPRT--HQWRTWLQCSRARAYALL 71
+L+ATQ Y++ERP+ + L+E L P + + + C+ + ++
Sbjct: 9 ILAATQR-------YYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNII 61
Query: 72 LQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFYPVF 131
LP+ WLP Y ++++LGDL+SG+S ++QLPQGLA+A+LA +PP+FGLYSSFYPV
Sbjct: 62 YMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVI 121
Query: 132 IYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALN-DSMINET----ARDAARVQVAST 186
+Y GTSRHIS+G FAV+S+M+G V L P + +N T ARDA RV+VA +
Sbjct: 122 MYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMS 181
Query: 187 LSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPL 246
+++L G+ Q LG+ FGFV YL+EPLVRG+TTAAAV VF S LKY+FG+ +SG
Sbjct: 182 VTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIF 241
Query: 247 SLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIGAT 306
S++Y+ + V + V ++ + +L+ K N++ +++LP PIP E ++ T
Sbjct: 242 SVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGT 301
Query: 307 GISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGKIF 366
GIS G LK + VDVVG +P GL+PP P+T LF + A IA+VGF++ IS+ K
Sbjct: 302 GISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTL 361
Query: 367 ALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLFI 426
A +HGY+VD NQEL+ALGL N IG +FQ F +SCS+SRSLVQE TGG +Q+AG ++SL I
Sbjct: 362 ANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMI 421
Query: 427 LLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATIL 486
LL+I+ G LF LP+AVL+AI+IVNLKGM Q SD+ W+ ++ +L IWL TF +++
Sbjct: 422 LLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLF 481
Query: 487 LNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFRSS 546
L LD GL+ AVI +LL V+ RTQ P Y VLG++P+TD+Y D+ Y E KE+ G+K+F+ +
Sbjct: 482 LGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQIN 541
Query: 547 ATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQAASPKG 606
A +Y+AN++ YS+ALK++ GV+ ++ ++K ++K
Sbjct: 542 APIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKY----------------------- 578
Query: 607 ASVSINVNTSLEDMRSNNVEDCKMMQVSSGDKMEDATANGQEDS---------KAPDGST 657
+++ + N+ + +++ + EDAT +ED K+
Sbjct: 579 ----------AKEVGNANMANATVVKADAEVDGEDATKPEEEDGEVKYPPIVIKSTFPEE 628
Query: 658 LKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAAC 708
++ P + H++ILD ++F+D+V +K+L I ++ ++ + VY+A C
Sbjct: 629 MQRFMPPGDNVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGC 679
>gi|16418413 solute carrier family 26, member 9 isoform a [Homo
sapiens]
Length = 791
Score = 504 bits (1298), Expect = e-142
Identities = 265/713 (37%), Positives = 433/713 (60%), Gaps = 14/713 (1%)
Query: 51 PRTHQWRTWLQCSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLA 110
P + R +CS A+ A++ LPVL WLP+Y ++D+++ DLL GLS +Q+PQG+A
Sbjct: 32 PVGEKLRNAFRCSSAKIKAVVFGLLPVLSWLPKYKIKDYIIPDLLGGLSGGSIQVPQGMA 91
Query: 111 YALLAGLPPVFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQ------ 164
+ALLA LP V GLYSSF+P+ YF G + GTFAV+S++VG++ LAP+
Sbjct: 92 FALLANLPAVNGLYSSFFPLLTYFFLGGVHQMVPGTFAVISILVGNICLQLAPESKFQVF 151
Query: 165 --ALNDSMINETARDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAA 222
A N+S ++ A +A R+ V++TL+ L + Q+GLG + FGFV YLSE +RG+ TAA
Sbjct: 152 NNATNESYVDTAAMEAERLHVSATLACLTAIIQMGLGFMQFGFVAIYLSESFIRGFMTAA 211
Query: 223 AVQVFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKL 282
+Q+ +S LKY+FGL + S++GP S+++T +++C LP + + +++ A ++G LV+VK
Sbjct: 212 GLQILISVLKYIFGLTIPSYTGPGSIVFTFIDICKNLPHTNIASLIFALISGAFLVLVKE 271
Query: 283 LNDKLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFS 342
LN + ++ PIP E++ ++ AT IS G + ++ + +VG I G PV+P +
Sbjct: 272 LNARYMHKIRFPIPTEMIVVVVATAISGGCKMPKKYHMQIVGEIQRGFPTPVSPVVSQWK 331
Query: 343 KLVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSM 402
++G+AF++A+V + I +++G+ A +HGY VDSNQE++ALG SN G F+ + C++
Sbjct: 332 DMIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCAL 391
Query: 403 SRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSD 462
S +L + GG SQVA SL +++ ++ LG + LPK+VL A+I VNLK L+QL+D
Sbjct: 392 SVTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTD 451
Query: 463 MRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDT 522
LW+ ++ D IW+V+F ++ L+L G+ V V FS+L+VV +TQ + L QV DT
Sbjct: 452 PYYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDT 511
Query: 523 DIYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKK 582
DIY + Y+ A++++G+K+ + +YFAN+E + + + G+D ++ K+K LKK
Sbjct: 512 DIYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKK 571
Query: 583 QEQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDMRSNNVEDCKMMQVS----SGDK 638
QE+ +++ Q+ L + + + + + +NN VS S D
Sbjct: 572 QEKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDS 631
Query: 639 MEDATANGQEDSKAP-DGSTLKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFR 697
A + ++AP + S + A P FH+LILD+ +SFVD + +K+L + +
Sbjct: 632 SSPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYG 691
Query: 698 EIEVEVYMAACHSPVVSQLEAGHFF-DASITKKHLFASVHDAVTFALQHPRPV 749
+I V+V++ H+ V + + G F D S+ KH+F S+HDAV FA + R V
Sbjct: 692 KIGVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQANARDV 744
>gi|217272867 solute carrier family 26, member 9 isoform b [Homo
sapiens]
Length = 887
Score = 504 bits (1298), Expect = e-142
Identities = 265/713 (37%), Positives = 433/713 (60%), Gaps = 14/713 (1%)
Query: 51 PRTHQWRTWLQCSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLA 110
P + R +CS A+ A++ LPVL WLP+Y ++D+++ DLL GLS +Q+PQG+A
Sbjct: 32 PVGEKLRNAFRCSSAKIKAVVFGLLPVLSWLPKYKIKDYIIPDLLGGLSGGSIQVPQGMA 91
Query: 111 YALLAGLPPVFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQ------ 164
+ALLA LP V GLYSSF+P+ YF G + GTFAV+S++VG++ LAP+
Sbjct: 92 FALLANLPAVNGLYSSFFPLLTYFFLGGVHQMVPGTFAVISILVGNICLQLAPESKFQVF 151
Query: 165 --ALNDSMINETARDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAA 222
A N+S ++ A +A R+ V++TL+ L + Q+GLG + FGFV YLSE +RG+ TAA
Sbjct: 152 NNATNESYVDTAAMEAERLHVSATLACLTAIIQMGLGFMQFGFVAIYLSESFIRGFMTAA 211
Query: 223 AVQVFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKL 282
+Q+ +S LKY+FGL + S++GP S+++T +++C LP + + +++ A ++G LV+VK
Sbjct: 212 GLQILISVLKYIFGLTIPSYTGPGSIVFTFIDICKNLPHTNIASLIFALISGAFLVLVKE 271
Query: 283 LNDKLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFS 342
LN + ++ PIP E++ ++ AT IS G + ++ + +VG I G PV+P +
Sbjct: 272 LNARYMHKIRFPIPTEMIVVVVATAISGGCKMPKKYHMQIVGEIQRGFPTPVSPVVSQWK 331
Query: 343 KLVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSM 402
++G+AF++A+V + I +++G+ A +HGY VDSNQE++ALG SN G F+ + C++
Sbjct: 332 DMIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCAL 391
Query: 403 SRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSD 462
S +L + GG SQVA SL +++ ++ LG + LPK+VL A+I VNLK L+QL+D
Sbjct: 392 SVTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTD 451
Query: 463 MRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDT 522
LW+ ++ D IW+V+F ++ L+L G+ V V FS+L+VV +TQ + L QV DT
Sbjct: 452 PYYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDT 511
Query: 523 DIYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKK 582
DIY + Y+ A++++G+K+ + +YFAN+E + + + G+D ++ K+K LKK
Sbjct: 512 DIYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKK 571
Query: 583 QEQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDMRSNNVEDCKMMQVS----SGDK 638
QE+ +++ Q+ L + + + + + +NN VS S D
Sbjct: 572 QEKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDS 631
Query: 639 MEDATANGQEDSKAP-DGSTLKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFR 697
A + ++AP + S + A P FH+LILD+ +SFVD + +K+L + +
Sbjct: 632 SSPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYG 691
Query: 698 EIEVEVYMAACHSPVVSQLEAGHFF-DASITKKHLFASVHDAVTFALQHPRPV 749
+I V+V++ H+ V + + G F D S+ KH+F S+HDAV FA + R V
Sbjct: 692 KIGVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQANARDV 744
>gi|4557535 solute carrier family 26, member 3 [Homo sapiens]
Length = 764
Score = 499 bits (1286), Expect = e-141
Identities = 275/731 (37%), Positives = 430/731 (58%), Gaps = 34/731 (4%)
Query: 29 YHMERPLLNQEHLEE----LGRWGSAPRTHQWRTWLQCSRARAYALLLQHLPVLVWLPRY 84
Y + RP+ + EE GR H + CS +A ++L P+ WLP Y
Sbjct: 9 YIVARPVYSTNAFEENHKKTGRHHKTFLDHL-KVCCSCSPQKAKRIVLSLFPIASWLPAY 67
Query: 85 PVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFYPVFIYFLFGTSRHISV 144
+++WLL D++SG+S I+ + QGLA+ALL +PPV+GLY+SF+P IY FGTSRHISV
Sbjct: 68 RLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISV 127
Query: 145 GTFAVMSVMVGSVTESLAPQALND----------SMINETARDAARVQVASTLSVLV--G 192
G F ++S+MVG +A+ D + N + D RV+VA+ SV V G
Sbjct: 128 GPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSG 187
Query: 193 LFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTV 252
+ Q+ G++ GFVV YLSE L+ G+TTAAAV V VSQLK++F L + SH+ P+S+ +
Sbjct: 188 IIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVL 247
Query: 253 LEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIGATGISYGM 312
V ++ ++ + +VTA + +V+ +VK +N + + +LP+PIP E + + A G+SYG
Sbjct: 248 YSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGC 307
Query: 313 GLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGKIFALRHGY 372
K+RF+V VVG++ G PP+ P+ + F VG F IA+V FA+A S+ +++L++ Y
Sbjct: 308 DFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDY 367
Query: 373 RVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLFILLIIVK 432
+D NQEL+ALGL N++ G+F+ F S ++SRS VQESTGG +Q+AG I ++ +L++++
Sbjct: 368 PLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLA 427
Query: 433 LGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATILLNLDLG 492
+G L L K+VLAA+ + NLKGML Q +++ LW+ ++ D LIW++TF TI+L L LG
Sbjct: 428 IGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLG 487
Query: 493 LVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFRSSATVYFA 552
L +V F LL +V RTQ P S L + T+IY++ +Y + E GVK+FR + +YFA
Sbjct: 488 LAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFA 547
Query: 553 NAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQAASPKGASVSIN 612
N F+ L G ++ ++ K L+ K+++LQK+ L+ +PKG +++
Sbjct: 548 NIGFFRRKLIDAVGFSPLRILRKRNKALR-----KIRKLQKQGLLQ---VTPKGFICTVD 599
Query: 613 VNTSLEDMRSNNVEDCKMMQVSSGDKMEDATANGQEDSKAPDGSTLKALGLPQPDFHSLI 672
++ NN + +++ D N D L + +P+ HSLI
Sbjct: 600 TIKDSDEELDNNQIEVLDQPINTTDLPFHIDWN--------DDLPLN-IEVPKISLHSLI 650
Query: 673 LDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGHFFDASITKKHLF 732
LD A+SF+D ++ LK+I +F I+V+VY+ + +L FFD + F
Sbjct: 651 LDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFF 710
Query: 733 ASVHDAVTFAL 743
++HDAV L
Sbjct: 711 LTIHDAVLHIL 721
>gi|45827802 prestin isoform c [Homo sapiens]
Length = 516
Score = 450 bits (1158), Expect = e-126
Identities = 236/506 (46%), Positives = 334/506 (66%), Gaps = 15/506 (2%)
Query: 15 LLSATQAMDLRRRDYHMERPLLNQEHLEE-LGRWGSAPRT--HQWRTWLQCSRARAYALL 71
+L+ATQ Y++ERP+ + L+E L P + + + C+ + ++
Sbjct: 9 ILAATQR-------YYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNII 61
Query: 72 LQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFYPVF 131
LP+ WLP Y ++++LGDL+SG+S ++QLPQGLA+A+LA +PP+FGLYSSFYPV
Sbjct: 62 YMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVI 121
Query: 132 IYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALN-DSMINET----ARDAARVQVAST 186
+Y GTSRHIS+G FAV+S+M+G V L P + +N T ARDA RV+VA +
Sbjct: 122 MYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMS 181
Query: 187 LSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPL 246
+++L G+ Q LG+ FGFV YL+EPLVRG+TTAAAV VF S LKY+FG+ +SG
Sbjct: 182 VTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIF 241
Query: 247 SLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIGAT 306
S++Y+ + V + V ++ + +L+ K N++ +++LP PIP E ++ T
Sbjct: 242 SVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGT 301
Query: 307 GISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGKIF 366
GIS G LK + VDVVG +P GL+PP P+T LF + A IA+VGF++ IS+ K
Sbjct: 302 GISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTL 361
Query: 367 ALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLFI 426
A +HGY+VD NQEL+ALGL N IG +FQ F +SCS+SRSLVQE TGG +Q+AG ++SL I
Sbjct: 362 ANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMI 421
Query: 427 LLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATIL 486
LL+I+ G LF LP+AVL+AI+IVNLKGM Q SD+ W+ ++ +L IWL TF +++
Sbjct: 422 LLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLF 481
Query: 487 LNLDLGLVVAVIFSLLLVVVRTQMPH 512
L LD GL+ AVI +LL V+ RTQ H
Sbjct: 482 LGLDYGLITAVIIALLTVIYRTQSFH 507
>gi|47131207 solute carrier family 26, member 1 isoform a [Homo
sapiens]
Length = 701
Score = 405 bits (1042), Expect = e-113
Identities = 240/711 (33%), Positives = 383/711 (53%), Gaps = 82/711 (11%)
Query: 57 RTWLQCSRAR--AYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALL 114
R W CS + AL+ LP WL +Y R++L GD++SGL + I+ +PQ +AY+LL
Sbjct: 34 RLWCSCSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLL 93
Query: 115 AGLPPVFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTE-------------SL 161
AGL P++ LY+SF+ IYFL GTSRH+SVG F+++ +MVG V + L
Sbjct: 94 AGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGL 153
Query: 162 APQALNDSMINETA------RDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLV 215
P A N S +N +A RD ++VA+ L+++ GL+QV +G++ GFV YLS+PL+
Sbjct: 154 QPGA-NSSTLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLL 212
Query: 216 RGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGV 275
G+ A+V + SQLK++ G+ + H GP ++ T L + Q+ V VVT+ V
Sbjct: 213 DGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLA 272
Query: 276 VLVVVKLLNDKLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVA 335
VL+ K L+D+ + +L +P+P ELL ++ AT +S+ L RF V G+IP G +PP
Sbjct: 273 VLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQV 332
Query: 336 PNTQLFSKLVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQC 395
P +L ++ A +A+V A +ISL ++FA HGY V +NQEL+A+G N++ C
Sbjct: 333 PEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHC 392
Query: 396 FPVSCSMSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKG 455
F S ++++SLV+ +TG +Q++ +S+ +LL+++ L LFHDL ++VLA +I+V+L+G
Sbjct: 393 FATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRG 452
Query: 456 MLRQLSDMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSV 515
LR++ D+ LW+ + AD L+W T +L++ + GL+ VI SLL + RTQ P ++
Sbjct: 453 ALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTAL 512
Query: 516 LGQVPDTDIYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQ 575
L ++ DT Y D E+ GV+VFR +Y+AN +F+ +L G+D + ++
Sbjct: 513 LARIGDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLDAGCMAAR 572
Query: 576 KKKLLKKQEQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDMRSNNVEDCKMMQVSS 635
RK+ S G
Sbjct: 573 ----------------------RKEGGSETGVG--------------------------- 583
Query: 636 GDKMEDATANGQEDSKAPDGSTLKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHD 695
E A G++ ST AL FH++++D L F+D + +L+++ D
Sbjct: 584 ----EGGPAQGEDLGPV---STRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRD 636
Query: 696 FREIEVEVYMAACHSPVVSQLEAGHFFDA----SITKKHLFASVHDAVTFA 742
+ + + + +A C PV L G F + ++ LF SVHDAV A
Sbjct: 637 YGALGISLLLACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTA 687
>gi|20336272 solute carrier family 26, member 1 isoform a [Homo
sapiens]
Length = 701
Score = 405 bits (1042), Expect = e-113
Identities = 240/711 (33%), Positives = 383/711 (53%), Gaps = 82/711 (11%)
Query: 57 RTWLQCSRAR--AYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALL 114
R W CS + AL+ LP WL +Y R++L GD++SGL + I+ +PQ +AY+LL
Sbjct: 34 RLWCSCSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLL 93
Query: 115 AGLPPVFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTE-------------SL 161
AGL P++ LY+SF+ IYFL GTSRH+SVG F+++ +MVG V + L
Sbjct: 94 AGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGL 153
Query: 162 APQALNDSMINETA------RDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLV 215
P A N S +N +A RD ++VA+ L+++ GL+QV +G++ GFV YLS+PL+
Sbjct: 154 QPGA-NSSTLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLL 212
Query: 216 RGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGV 275
G+ A+V + SQLK++ G+ + H GP ++ T L + Q+ V VVT+ V
Sbjct: 213 DGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLA 272
Query: 276 VLVVVKLLNDKLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVA 335
VL+ K L+D+ + +L +P+P ELL ++ AT +S+ L RF V G+IP G +PP
Sbjct: 273 VLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQV 332
Query: 336 PNTQLFSKLVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQC 395
P +L ++ A +A+V A +ISL ++FA HGY V +NQEL+A+G N++ C
Sbjct: 333 PEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHC 392
Query: 396 FPVSCSMSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKG 455
F S ++++SLV+ +TG +Q++ +S+ +LL+++ L LFHDL ++VLA +I+V+L+G
Sbjct: 393 FATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRG 452
Query: 456 MLRQLSDMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSV 515
LR++ D+ LW+ + AD L+W T +L++ + GL+ VI SLL + RTQ P ++
Sbjct: 453 ALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTAL 512
Query: 516 LGQVPDTDIYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQ 575
L ++ DT Y D E+ GV+VFR +Y+AN +F+ +L G+D + ++
Sbjct: 513 LARIGDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLDAGCMAAR 572
Query: 576 KKKLLKKQEQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDMRSNNVEDCKMMQVSS 635
RK+ S G
Sbjct: 573 ----------------------RKEGGSETGVG--------------------------- 583
Query: 636 GDKMEDATANGQEDSKAPDGSTLKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHD 695
E A G++ ST AL FH++++D L F+D + +L+++ D
Sbjct: 584 ----EGGPAQGEDLGPV---STRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRD 636
Query: 696 FREIEVEVYMAACHSPVVSQLEAGHFFDA----SITKKHLFASVHDAVTFA 742
+ + + + +A C PV L G F + ++ LF SVHDAV A
Sbjct: 637 YGALGISLLLACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTA 687
>gi|100913030 solute carrier family 26 member 2 [Homo sapiens]
Length = 739
Score = 404 bits (1037), Expect = e-112
Identities = 229/703 (32%), Positives = 383/703 (54%), Gaps = 83/703 (11%)
Query: 61 QCSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPV 120
QCS A+A ++L LPVL WLP+Y ++ +LGD++SGL V I+ +PQ +AY+LLAG PV
Sbjct: 79 QCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQEPV 138
Query: 121 FGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTE---------------SLAPQA 165
+GLY+SF+ IYFL GTSRHISVG F V+ +M+G + SL +
Sbjct: 139 YGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETVDRELQKAGYDNAHSAPSLGMVS 198
Query: 166 LNDSMINETA-----RDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTT 220
+++N T+ + + V ST++ + G++QV +G GFV YLS+ L+ G+ T
Sbjct: 199 NGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGFFQVGFVSVYLSDALLSGFVT 258
Query: 221 AAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVV 280
A+ + SQ KY+ GL+L +G SLI T + V + ++ + ++T+ + +VL+
Sbjct: 259 GASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRNIHKTNLCDLITSLLCLLVLLPT 318
Query: 281 KLLNDKLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQL 340
K LN+ + +L PIP EL+ ++ AT S+ L + + G+IP G +PP P L
Sbjct: 319 KELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHENYNSSIAGHIPTGFMPPKVPEWNL 378
Query: 341 FSKLVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSC 400
+ A I+++GFAI +SL ++FA +HGY V +NQE+ A+G N+I F CF S
Sbjct: 379 IPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCFTTSA 438
Query: 401 SMSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQL 460
+++++LV+ESTG ++Q++G +++L +LL+++ + LF+ L K+VL I IVNL+G LR+
Sbjct: 439 ALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQKSVLGVITIVNLRGALRKF 498
Query: 461 SDMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVP 520
D+ +W +R D +IW VT ++ LL+ ++GL+V V FS+ V++RTQ P S+LG V
Sbjct: 499 RDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGVCFSIFCVILRTQKPKSSLLGLVE 558
Query: 521 DTDIYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLL 580
+++++ V+ Y + G+K+FR A +Y+ N E + AL ++ + ++ KK
Sbjct: 559 ESEVFESVSAYKNLQIKPGIKIFRFVAPLYYINKECFKSALYKQTVNPILIKVAWKK--- 615
Query: 581 KKQEQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDMRSNN-VEDCKMMQVSSGDKM 639
+ K++++ + G ++V S + + + V DC +Q
Sbjct: 616 -----------AAKRKIKEKVVTLGGIQDEMSVQLSHDPLELHTIVIDCSAIQ------- 657
Query: 640 EDATANGQEDSKAPDGSTLKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREI 699
F+DT + +LK + D+ I
Sbjct: 658 ----------------------------------------FLDTAGIHTLKEVRRDYEAI 677
Query: 700 EVEVYMAACHSPVVSQLEAGHFFDASITKKHLFASVHDAVTFA 742
++V +A C+ V L G + + LF SV++A+ FA
Sbjct: 678 GIQVLLAQCNPTVRDSLTNGEYCKKE-EENLLFYSVYEAMAFA 719
>gi|16418457 solute carrier family 26, member 8 isoform a [Homo
sapiens]
Length = 970
Score = 373 bits (957), Expect = e-103
Identities = 241/787 (30%), Positives = 413/787 (52%), Gaps = 76/787 (9%)
Query: 21 AMDLRRRDYHMERPLLNQEHLEELGRWGSAP---RTHQWRTWLQCSRARAYALLLQHLPV 77
A D++R Y+ E QEH + G+ T + +CS R +L P
Sbjct: 22 AYDVKREVYNEET--FQQEHKRKASSSGNMNINITTFRHHVQCRCSWHRFLRCVLTIFPF 79
Query: 78 LVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAG--LPPVFGLYSSFYPVFIYFL 135
L W+ Y ++DWLLGDLL+G+SV ++Q+PQGL +LLA +PP+ Y++F IY +
Sbjct: 80 LEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPPLNIAYAAFCSSVIYVI 139
Query: 136 FGTSRHISVGTFAVMSVMVGSVTESLAP----QALNDSMI-NETARDA------ARVQVA 184
FG+ +S+G+F ++S ++ +V + ++P Q + S + NE + + + V
Sbjct: 140 FGSCHQMSIGSFFLVSALLINVLK-VSPFNNGQLVMGSFVKNEFSAPSYLMGYNKSLSVV 198
Query: 185 STLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSG 244
+T + L G+ Q+ +G++ GF+ TYL E + Y A A+ + +SQL ++FG+ +S H+G
Sbjct: 199 ATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIMLSQLTFIFGIMISFHAG 258
Query: 245 PLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIG 304
P+S Y ++ C LP++ +++ V L + K + Q P+ P EL +IG
Sbjct: 259 PISFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRISFNQY-PIEFPMELFLIIG 317
Query: 305 ATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGK 364
T I+ + + ++ IP + PV P+ L K++ AF++++V + I LGK
Sbjct: 318 FTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSSFLLIFLGK 377
Query: 365 IFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSL 424
A H Y V+SNQ+L+A+GL N++ F+ + +++R+++Q+ +GG Q A + +
Sbjct: 378 KIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQFASLVGAG 437
Query: 425 FILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTAT 484
+LL++VK+G F+ LP AVLA II+ N+ L +S++ SLW+ ++ D +W++TF+++
Sbjct: 438 VMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYDCALWMMTFSSS 497
Query: 485 ILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFR 544
I L LD+GL+++V+ + + VR+ +LGQ+P+T+IYR + +Y E + GVK+F+
Sbjct: 498 IFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSINDYREIITIPGVKIFQ 557
Query: 545 SSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKL-----KQLQKEEKLR- 598
+++ F N + LK + +VD + K LK++E L LQ + R
Sbjct: 558 CCSSITFVNVYY----LKHKLLKEVDMV----KVPLKEEEIFSLFNSSDTNLQGGKICRC 609
Query: 599 -------------------KQAASPKGASVSINVNTSLEDMRSNNV--EDCKMMQVSS-G 636
+ P+ +S+++ + E M ++ ED VSS
Sbjct: 610 FCNCDDLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTSQTASEDQVPYTVSSVS 669
Query: 637 DKMEDATANGQEDSKAPDGSTLKAL-GLPQ-------------------PDFHSLILDLG 676
K + E+ P+ S+ + GLP P H++ILD
Sbjct: 670 QKNQGQQYEEVEEVWLPNNSSRNSSPGLPDVAESQGRRSLIPYSDASLLPSVHTIILDFS 729
Query: 677 ALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGHFFDASITKKHLFASVH 736
+ +VD+ L L+ I + F+ + + +A CHS +V E FFDA ITK LF SVH
Sbjct: 730 MVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGITKTQLFLSVH 789
Query: 737 DAVTFAL 743
DAV FAL
Sbjct: 790 DAVLFAL 796
>gi|16306483 solute carrier family 26, member 7 isoform a [Homo
sapiens]
Length = 656
Score = 307 bits (787), Expect = 2e-83
Identities = 164/497 (32%), Positives = 291/497 (58%), Gaps = 10/497 (2%)
Query: 73 QHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFYPVFI 132
+ LP+L W P Y +++ LL D +SG+ +A+ Q+ QGLA+A+L+ + PVFGLY S +P I
Sbjct: 30 RRLPILDWAPHYNLKENLLPDTVSGIMLAVQQVTQGLAFAVLSSVHPVFGLYGSLFPAII 89
Query: 133 YFLFGTSRHISVGTFAVMSVMVGSVTESLAPQAL-------NDSMINETARDAARVQVAS 185
Y +FG H++ GTFA+ S++ + E + PQ + N S++ + + R+ VA+
Sbjct: 90 YAIFGMGHHVATGTFALTSLISANAVERIVPQNMQNLTTQSNTSVLGLSDFEMQRIHVAA 149
Query: 186 TLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGP 245
+S L G+ QV + ++ G ++EP++ TT AA V SQ+KY+ G+ + SGP
Sbjct: 150 AVSFLGGVIQVAMFVLQLGSATFVVTEPVISAMTTGAATHVVTSQVKYLLGMKMPYISGP 209
Query: 246 LSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIGA 305
L Y V + ++ ++ + ++ VVLV+VK LN++ ++++ + +P +L+ +I A
Sbjct: 210 LGFFYIYAYVFENIKSVRLEALLLSLLSIVVLVLVKELNEQFKRKIKVVLPVDLVLIIAA 269
Query: 306 TGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGKI 365
+ Y +++ + ++VVG+IP G+ P AP + S ++ AF +A+VG+ +++L +
Sbjct: 270 SFACYCTNMENTYGLEVVGHIPQGIPSPRAPPMNILSAVITEAFGVALVGYVASLALAQG 329
Query: 366 FALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLF 425
A + Y +D NQE +A GLSN++ F C P + +M R+ STG +QVA IS +F
Sbjct: 330 SAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAAAMGRTAGLYSTGAKTQVACLISCIF 389
Query: 426 ILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATI 485
+L++I +G L + LP VLA+II+V LKGML Q D++ W ++ D IW+ T+ TI
Sbjct: 390 VLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVDKIDWGIWVSTYVFTI 449
Query: 486 LLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFRS 545
++GL+ V+ ++ +V+ R P + ++ V +++ ++ VK+
Sbjct: 450 CFAANVGLLFGVVCTIAIVIGR--FPRAMTVSIKNMKEMEFKVKTEMDSETLQQVKIISI 507
Query: 546 SATVYFANA-EFYSDAL 561
+ + F NA +FY+D +
Sbjct: 508 NNPLVFLNAKKFYTDLM 524
>gi|20336282 solute carrier family 26, member 7 isoform b [Homo
sapiens]
Length = 663
Score = 307 bits (787), Expect = 2e-83
Identities = 164/497 (32%), Positives = 291/497 (58%), Gaps = 10/497 (2%)
Query: 73 QHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFYPVFI 132
+ LP+L W P Y +++ LL D +SG+ +A+ Q+ QGLA+A+L+ + PVFGLY S +P I
Sbjct: 30 RRLPILDWAPHYNLKENLLPDTVSGIMLAVQQVTQGLAFAVLSSVHPVFGLYGSLFPAII 89
Query: 133 YFLFGTSRHISVGTFAVMSVMVGSVTESLAPQAL-------NDSMINETARDAARVQVAS 185
Y +FG H++ GTFA+ S++ + E + PQ + N S++ + + R+ VA+
Sbjct: 90 YAIFGMGHHVATGTFALTSLISANAVERIVPQNMQNLTTQSNTSVLGLSDFEMQRIHVAA 149
Query: 186 TLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGP 245
+S L G+ QV + ++ G ++EP++ TT AA V SQ+KY+ G+ + SGP
Sbjct: 150 AVSFLGGVIQVAMFVLQLGSATFVVTEPVISAMTTGAATHVVTSQVKYLLGMKMPYISGP 209
Query: 246 LSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIGA 305
L Y V + ++ ++ + ++ VVLV+VK LN++ ++++ + +P +L+ +I A
Sbjct: 210 LGFFYIYAYVFENIKSVRLEALLLSLLSIVVLVLVKELNEQFKRKIKVVLPVDLVLIIAA 269
Query: 306 TGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGKI 365
+ Y +++ + ++VVG+IP G+ P AP + S ++ AF +A+VG+ +++L +
Sbjct: 270 SFACYCTNMENTYGLEVVGHIPQGIPSPRAPPMNILSAVITEAFGVALVGYVASLALAQG 329
Query: 366 FALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLF 425
A + Y +D NQE +A GLSN++ F C P + +M R+ STG +QVA IS +F
Sbjct: 330 SAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAAAMGRTAGLYSTGAKTQVACLISCIF 389
Query: 426 ILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATI 485
+L++I +G L + LP VLA+II+V LKGML Q D++ W ++ D IW+ T+ TI
Sbjct: 390 VLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVDKIDWGIWVSTYVFTI 449
Query: 486 LLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFRS 545
++GL+ V+ ++ +V+ R P + ++ V +++ ++ VK+
Sbjct: 450 CFAANVGLLFGVVCTIAIVIGR--FPRAMTVSIKNMKEMEFKVKTEMDSETLQQVKIISI 507
Query: 546 SATVYFANA-EFYSDAL 561
+ + F NA +FY+D +
Sbjct: 508 NNPLVFLNAKKFYTDLM 524
>gi|65506789 solute carrier family 26, member 10 [Homo sapiens]
Length = 563
Score = 279 bits (713), Expect = 8e-75
Identities = 147/371 (39%), Positives = 230/371 (61%), Gaps = 2/371 (0%)
Query: 108 GLAYALLAGLPPVFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQAL- 166
G+A+ALLA +PPVFGLY+SF+PV IY L GT RH+S GTFA++S+M GS E L P+ L
Sbjct: 41 GMAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERLVPEPLV 100
Query: 167 -NDSMINETARDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQ 225
N S I + DA RV VA+ ++ G +G+ ++ G + T+LSEP+V+ T+ AA+
Sbjct: 101 GNLSGIEKEQLDAQRVGVAAAVAFGSGALMLGMFVLQLGVLSTFLSEPVVKALTSGAALH 160
Query: 226 VFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLND 285
V +SQL + GL L G SL T+ + LP+S + +A++ +LV VK LN
Sbjct: 161 VLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELTISALSLALLVPVKELNV 220
Query: 286 KLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLV 345
+ + +LP PIPGE++ ++ A+ + + + R++V +VG +P G P+ PN +++
Sbjct: 221 RFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLPGGFPQPLLPNLAELPRIL 280
Query: 346 GSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRS 405
+ IA+V FA++ SL I A ++ Y +DSNQE +A G SNLI +F CFP S +++ +
Sbjct: 281 ADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNLISSLFSCFPNSATLATT 340
Query: 406 LVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRS 465
+ GG +Q+AG S +L +++ LG F+ LPKAVLA I I +++ + Q+ ++
Sbjct: 341 NLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACINISSMRQVFCQMQELPQ 400
Query: 466 LWKANRADLLI 476
LW +R D L+
Sbjct: 401 LWHISRVDFLL 411
>gi|217272870 solute carrier family 26, member 9 isoform c [Homo
sapiens]
Length = 459
Score = 259 bits (663), Expect = 5e-69
Identities = 144/412 (34%), Positives = 240/412 (58%), Gaps = 6/412 (1%)
Query: 344 LVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMS 403
++G+AF++A+V + I +++G+ A +HGY VDSNQE++ALG SN G F+ + C++S
Sbjct: 1 MIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALS 60
Query: 404 RSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDM 463
+L + GG SQVA SL +++ ++ LG + LPK+VL A+I VNLK L+QL+D
Sbjct: 61 VTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDP 120
Query: 464 RSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTD 523
LW+ ++ D IW+V+F ++ L+L G+ V V FS+L+VV +TQ + L QV DTD
Sbjct: 121 YYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTD 180
Query: 524 IYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQ 583
IY + Y+ A++++G+K+ + +YFAN+E + + + G+D ++ K+K LKKQ
Sbjct: 181 IYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQ 240
Query: 584 EQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDMRSNNVEDCKMMQVS----SGDKM 639
E+ +++ Q+ L + + + + + +NN VS S D
Sbjct: 241 EKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSS 300
Query: 640 EDATANGQEDSKAP-DGSTLKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFRE 698
A + ++AP + S + A P FH+LILD+ +SFVD + +K+L + + +
Sbjct: 301 SPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGK 360
Query: 699 IEVEVYMAACHSPVVSQLEAGHFF-DASITKKHLFASVHDAVTFALQHPRPV 749
I V+V++ H+ V + + G F D S+ KH+F S+HDAV FA + R V
Sbjct: 361 IGVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQANARDV 412
>gi|45827804 prestin isoform d [Homo sapiens]
Length = 335
Score = 248 bits (634), Expect = 1e-65
Identities = 136/323 (42%), Positives = 201/323 (62%), Gaps = 15/323 (4%)
Query: 15 LLSATQAMDLRRRDYHMERPLLNQEHLEE-LGRWGSAPRT--HQWRTWLQCSRARAYALL 71
+L+ATQ Y++ERP+ + L+E L P + + + C+ + ++
Sbjct: 9 ILAATQR-------YYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNII 61
Query: 72 LQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFYPVF 131
LP+ WLP Y ++++LGDL+SG+S ++QLPQGLA+A+LA +PP+FGLYSSFYPV
Sbjct: 62 YMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVI 121
Query: 132 IYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALN-DSMINET----ARDAARVQVAST 186
+Y GTSRHIS+G FAV+S+M+G V L P + +N T ARDA RV+VA +
Sbjct: 122 MYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMS 181
Query: 187 LSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPL 246
+++L G+ Q LG+ FGFV YL+EPLVRG+TTAAAV VF S LKY+FG+ +SG
Sbjct: 182 VTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIF 241
Query: 247 SLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIGAT 306
S++Y+ + V + V ++ + +L+ K N++ +++LP PIP E ++ T
Sbjct: 242 SVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGT 301
Query: 307 GISYGMGLKHRFEVDVVGNIPAG 329
GIS G LK + VDVVG +P G
Sbjct: 302 GISAGFNLKESYNVDVVGTLPLG 324
>gi|20336285 solute carrier family 26, member 8 isoform b [Homo
sapiens]
Length = 865
Score = 234 bits (598), Expect = 2e-61
Identities = 172/606 (28%), Positives = 290/606 (47%), Gaps = 65/606 (10%)
Query: 189 VLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSL 248
+ VGL QV GL + L PL Y + ++V +FG G L
Sbjct: 100 ISVGLVQVPQGLT-LSLLARQLIPPLNIAYAAFCSSVIYV-----IFGSCHQMSIGSFFL 153
Query: 249 IYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLL---NDKLQQQLPMPIPGELLTLIGA 305
+ +L K+ G +V + L N L ++ +IG
Sbjct: 154 VSALLINVLKVSPFNNGQLVMGSFVKNEFSAPSYLMGYNKSLSVVATTTFLTGIIQIIGF 213
Query: 306 TGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGKI 365
T I+ + + ++ IP + PV P+ L K++ AF++++V + I LGK
Sbjct: 214 TVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSSFLLIFLGKK 273
Query: 366 FALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLF 425
A H Y V+SNQ+L+A+GL N++ F+ + +++R+++Q+ +GG Q A + +
Sbjct: 274 IASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQFASLVGAGV 333
Query: 426 ILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATI 485
+LL++VK+G F+ LP AVLA II+ N+ L +S++ SLW+ ++ D +W++TF+++I
Sbjct: 334 MLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYDCALWMMTFSSSI 393
Query: 486 LLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFRS 545
L LD+GL+++V+ + + VR+ +LGQ+P+T+IYR + +Y E + GVK+F+
Sbjct: 394 FLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSINDYREIITIPGVKIFQC 453
Query: 546 SATVYFANAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKL-----KQLQKEEKLR-- 598
+++ F N + LK + +VD + K LK++E L LQ + R
Sbjct: 454 CSSITFVNVYY----LKHKLLKEVDMV----KVPLKEEEIFSLFNSSDTNLQGGKICRCF 505
Query: 599 ------------------KQAASPKGASVSINVNTSLEDMRSNNV--EDCKMMQVSS-GD 637
+ P+ +S+++ + E M ++ ED VSS
Sbjct: 506 CNCDDLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTSQTASEDQVPYTVSSVSQ 565
Query: 638 KMEDATANGQEDSKAPDGSTLKAL-GLPQ-------------------PDFHSLILDLGA 677
K + E+ P+ S+ + GLP P H++ILD
Sbjct: 566 KNQGQQYEEVEEVWLPNNSSRNSSPGLPDVAESQGRRSLIPYSDASLLPSVHTIILDFSM 625
Query: 678 LSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGHFFDASITKKHLFASVHD 737
+ +VD+ L L+ I + F+ + + +A CHS +V E FFDA ITK LF SVHD
Sbjct: 626 VHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGITKTQLFLSVHD 685
Query: 738 AVTFAL 743
AV FAL
Sbjct: 686 AVLFAL 691
Score = 85.1 bits (209), Expect = 2e-16
Identities = 50/142 (35%), Positives = 81/142 (57%), Gaps = 7/142 (4%)
Query: 21 AMDLRRRDYHMERPLLNQEHLEELGRWGSAP---RTHQWRTWLQCSRARAYALLLQHLPV 77
A D++R Y+ E QEH + G+ T + +CS R +L P
Sbjct: 22 AYDVKREVYNEET--FQQEHKRKASSSGNMNINITTFRHHVQCRCSWHRFLRCMLTIFPF 79
Query: 78 LVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAG--LPPVFGLYSSFYPVFIYFL 135
L W+ Y ++DWLLGDLL+G+SV ++Q+PQGL +LLA +PP+ Y++F IY +
Sbjct: 80 LEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPPLNIAYAAFCSSVIYVI 139
Query: 136 FGTSRHISVGTFAVMSVMVGSV 157
FG+ +S+G+F ++S ++ +V
Sbjct: 140 FGSCHQMSIGSFFLVSALLINV 161
>gi|85540447 solute carrier family 26, member 11 [Homo sapiens]
Length = 606
Score = 226 bits (576), Expect = 6e-59
Identities = 149/474 (31%), Positives = 248/474 (52%), Gaps = 53/474 (11%)
Query: 69 ALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFY 128
A L + LP+L WLP Y ++ WL D ++GLSV + +PQ LAYA +AGLPP +GLYS+F
Sbjct: 28 AALQRRLPILAWLPSYSLQ-WLKMDFVAGLSVGLTAIPQALAYAEVAGLPPQYGLYSAFM 86
Query: 129 PVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLAPQALNDSMINETARDAARVQVASTLS 188
F+YF GTSR +++G A+MS++V T +E A A L+
Sbjct: 87 GCFVYFFLGTSRDVTLGPTAIMSLLVSFYT------------FHEPA-------YAVLLA 127
Query: 189 VLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSL 248
L G Q+ +G++ GF++ ++S P+++G+T+AAAV + Q+K + GL L +
Sbjct: 128 FLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIGFGQIKNLLGLQNIPRPFFLQV 187
Query: 249 IYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELL-------- 300
+T L + +++VG V V ++L+V+KL+ D + P PG L
Sbjct: 188 YHTFLRIA----ETRVGDAVLGLVCMLLLLVLKLMRDHVPPVHPEMPPGVRLSRGLVWAA 243
Query: 301 -TLIGATGISYGMGLKHRFEV----------DVVGNIPAGLVPP----VAPNTQLFSKLV 345
T A +S+ + + FEV + +P +PP A T F+++V
Sbjct: 244 TTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPFSVTTANGTISFTEMV 303
Query: 346 ----GSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSCS 401
+ ++G +I++ K FA ++ YR+D+NQEL+A+GL+N++G + +PV+ S
Sbjct: 304 QDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIGLTNMLGSLVSSYPVTGS 363
Query: 402 MSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQLS 461
R+ V +G + G ++ + +LL + L LF+ +PK+ LAA+II+ + L
Sbjct: 364 FGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALAAVIIMAV-APLFDTK 422
Query: 462 DMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSV 515
R+LW+ R DLL VTF + G++ + SLL+++ P V
Sbjct: 423 IFRTLWRVKRLDLLPLCVTF-LLCFWEVQYGILAGALVSLLMLLHSAARPETKV 475
>gi|20336274 solute carrier family 26, member 1 isoform b [Homo
sapiens]
Length = 224
Score = 115 bits (288), Expect = 2e-25
Identities = 66/164 (40%), Positives = 97/164 (59%), Gaps = 22/164 (13%)
Query: 57 RTWLQCSRAR--AYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALL 114
R W CS + AL+ LP WL +Y R++L GD++SGL + I+ +PQ +AY+LL
Sbjct: 34 RLWCSCSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLL 93
Query: 115 AGLPPVFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVT-------------ESL 161
AGL P++ LY+SF+ IYFL GTSRH+SVG F+++ +MVG V + L
Sbjct: 94 AGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGL 153
Query: 162 APQALNDSMINETA------RDAARVQVASTLSVLVGLFQVGLG 199
P A N S +N +A RD ++VA+ L+++ GL+Q G
Sbjct: 154 QPGA-NSSTLNGSAAMLDCGRDCYAIRVATALTLMTGLYQTSWG 196
>gi|116256458 hypothetical protein LOC121053 [Homo sapiens]
Length = 185
Score = 34.7 bits (78), Expect = 0.34
Identities = 25/104 (24%), Positives = 49/104 (47%), Gaps = 11/104 (10%)
Query: 575 QKKKLLKKQEQLKLKQLQKEEKLRKQ-AASPKGA----------SVSINVNTSLEDMRSN 623
++ LL + + + + EKLRK+ AA+P G S I ++ +L +M +
Sbjct: 64 ERSPLLDQVQTFLPQMARANEKLRKEMAAAPPGRFNIENIDGPHSKVIQMDVALFEMNQS 123
Query: 624 NVEDCKMMQVSSGDKMEDATANGQEDSKAPDGSTLKALGLPQPD 667
+ ++ + SS D E+++ + ED P T+ + LP +
Sbjct: 124 DSKEVDSSEESSQDSSENSSESEDEDDSIPSEVTIDNIKLPNSE 167
>gi|62422577 neurobeachin [Homo sapiens]
Length = 2946
Score = 32.7 bits (73), Expect = 1.3
Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 4/81 (4%)
Query: 166 LNDSMINETARDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQ 225
LNDS + T + L V + + LG F V+ YL E R + T A ++
Sbjct: 514 LNDSQVETTVCATLLAFLVELLKSSVAMQEQMLGGKGF-LVIGYLLEKSSRVHITRAVLE 572
Query: 226 VFVSQLKYVFGLHLSSHSGPL 246
F+S KY+ GL SH PL
Sbjct: 573 QFLSFAKYLDGL---SHGAPL 590
>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
Length = 450
Score = 32.3 bits (72), Expect = 1.7
Identities = 31/113 (27%), Positives = 52/113 (46%), Gaps = 22/113 (19%)
Query: 568 DVDFLIS----QKKKLLKKQEQLKLKQLQKEEKLRK---------------QAASPKGAS 608
+V+FL S QK+KLL+K ++L+ K+ +K+ K +K ++S +S
Sbjct: 209 EVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSS 268
Query: 609 VSINVNTSLEDMRSNNVEDCKMMQVSSGDKMEDATANGQEDSKAPDGSTLKAL 661
S + S + SNN E K +Q K + + DS+ D S + L
Sbjct: 269 SSTETSESSSESESNNKE--KKIQ-RKKRKKNKCSGHNNSDSEEKDKSKKRKL 318
>gi|55749531 splicing factor 3B subunit 2 [Homo sapiens]
Length = 895
Score = 32.3 bits (72), Expect = 1.7
Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 13/88 (14%)
Query: 580 LKKQEQLKLKQLQKEEKLRKQAASPKGASVS------INVNTSLEDMRSNNVEDCKMMQ- 632
LK+ Q ++ Q+EE++ A S G S S ++V+ ++ + N + K Q
Sbjct: 279 LKESRQEEMNSQQEEEEMETDARSSLGQSASETEEDTVSVSKKEKNRKRRNRKKKKKPQR 338
Query: 633 ------VSSGDKMEDATANGQEDSKAPD 654
SSGD+ +D+T + DS A D
Sbjct: 339 VRGVSSESSGDREKDSTRSRGSDSPAAD 366
>gi|157649069 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform b [Homo sapiens]
Length = 1149
Score = 32.0 bits (71), Expect = 2.2
Identities = 50/198 (25%), Positives = 90/198 (45%), Gaps = 19/198 (9%)
Query: 504 VVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEV--RGVKVFRSSA--TVYFANAEFYSD 559
V+VRT + + DT IY +AE S+ KE+ + ++ F + T+ FA AE
Sbjct: 543 VIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISES 602
Query: 560 ALKQRCGVDVDFLISQKKKLLKKQEQLKL--KQLQK------EEKLRKQAASP----KGA 607
++ V S + +LLK +E +L K LQ E+KL+ Q A
Sbjct: 603 DFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKA 662
Query: 608 SVSINVNTSLEDMRSNNV-EDCKMMQVSSG-DKMEDATANGQEDSKAPDGSTLKALGLPQ 665
+ I + T + + N+ CK+++ + G + + + +G ++ + +TL +
Sbjct: 663 DIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKE 722
Query: 666 PDFHSLILDLGALSFVDT 683
DF +LI+D L + T
Sbjct: 723 NDF-ALIIDGKTLKYALT 739
>gi|17978471 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform a [Homo sapiens]
Length = 1164
Score = 32.0 bits (71), Expect = 2.2
Identities = 50/198 (25%), Positives = 90/198 (45%), Gaps = 19/198 (9%)
Query: 504 VVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEV--RGVKVFRSSA--TVYFANAEFYSD 559
V+VRT + + DT IY +AE S+ KE+ + ++ F + T+ FA AE
Sbjct: 558 VIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISES 617
Query: 560 ALKQRCGVDVDFLISQKKKLLKKQEQLKL--KQLQK------EEKLRKQAASP----KGA 607
++ V S + +LLK +E +L K LQ E+KL+ Q A
Sbjct: 618 DFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKA 677
Query: 608 SVSINVNTSLEDMRSNNV-EDCKMMQVSSG-DKMEDATANGQEDSKAPDGSTLKALGLPQ 665
+ I + T + + N+ CK+++ + G + + + +G ++ + +TL +
Sbjct: 678 DIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRKE 737
Query: 666 PDFHSLILDLGALSFVDT 683
DF +LI+D L + T
Sbjct: 738 NDF-ALIIDGKTLKYALT 754
>gi|45827729 scribble isoform b [Homo sapiens]
Length = 1630
Score = 32.0 bits (71), Expect = 2.2
Identities = 19/75 (25%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 584 EQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDMRSNNVEDCKMMQVSSGDKMEDAT 643
EQL ++ QK +L + +G +++ +D+R E+ + +Q + +A
Sbjct: 1350 EQLSFRERQKYFELEVRVPQAEGPPKRVSL-VGADDLRKMQEEEARKLQQKRAQMLREAA 1408
Query: 644 ANGQEDSKAPDGSTL 658
G E A DG TL
Sbjct: 1409 EAGAEARLALDGETL 1423
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,940,830
Number of Sequences: 37866
Number of extensions: 1083806
Number of successful extensions: 3722
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 3622
Number of HSP's gapped (non-prelim): 86
length of query: 759
length of database: 18,247,518
effective HSP length: 110
effective length of query: 649
effective length of database: 14,082,258
effective search space: 9139385442
effective search space used: 9139385442
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.