Search of human proteins with 92110023

Search of human proteins with 92110023

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|92110023 PQ loop repeat containing 2 isoform 2 [Homo
sapiens]
         (226 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|92110021 PQ loop repeat containing 2 isoform 1 [Homo sapiens]      441   e-124
gi|92110025 PQ loop repeat containing 2 isoform 1 [Homo sapiens]      441   e-124
gi|92110023 PQ loop repeat containing 2 isoform 2 [Homo sapiens]      441   e-124
gi|194018508 hypothetical protein LOC152078 isoform 1 [Homo sapi...    60   2e-09
gi|153791811 hypothetical protein LOC152078 isoform 3 [Homo sapi...    60   2e-09
gi|58533182 transmembrane protein 44 isoform b [Homo sapiens]          48   8e-06
gi|38679902 transmembrane protein 44 isoform a [Homo sapiens]          48   8e-06
gi|194018506 hypothetical protein LOC152078 isoform 2 [Homo sapi...    40   0.002
gi|119943110 cystinosis, nephropathic isoform 2 [Homo sapiens]         34   0.089
gi|119943118 cystinosis, nephropathic isoform 1 [Homo sapiens]         34   0.089
gi|45505167 immunoglobulin superfamily, member 1 isoform 1 [Homo...    29   2.9  
gi|22027651 adaptor-related protein complex 1 beta 1 subunit iso...    29   2.9  
gi|22027653 adaptor-related protein complex 1 beta 1 subunit iso...    29   2.9  
gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens]      28   4.9  
gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens]      28   4.9  
gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens]      28   4.9  
gi|13491166 pumilio 1 isoform 2 [Homo sapiens]                         28   6.4  
gi|66932909 pumilio 1 isoform 1 [Homo sapiens]                         28   6.4  

>gi|92110021 PQ loop repeat containing 2 isoform 1 [Homo sapiens]
          Length = 291

 Score =  441 bits (1135), Expect = e-124
 Identities = 226/226 (100%), Positives = 226/226 (100%)

Query: 1   MDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLVMLTLYFYYKFRTRP 60
           MDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLVMLTLYFYYKFRTRP
Sbjct: 66  MDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLVMLTLYFYYKFRTRP 125

Query: 61  SLLSAPINSVLLFLMGMACATPLLSAAGPVAAPREAFRGRALLSVESGSKPFTRQEVIGF 120
           SLLSAPINSVLLFLMGMACATPLLSAAGPVAAPREAFRGRALLSVESGSKPFTRQEVIGF
Sbjct: 126 SLLSAPINSVLLFLMGMACATPLLSAAGPVAAPREAFRGRALLSVESGSKPFTRQEVIGF 185

Query: 121 VIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGLSVLLKNPEEGQSE 180
           VIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGLSVLLKNPEEGQSE
Sbjct: 186 VIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGLSVLLKNPEEGQSE 245

Query: 181 GSYLLHHLPWLVGSLGVLLLDTIISIQFLVYRRSTAASELEPLLPS 226
           GSYLLHHLPWLVGSLGVLLLDTIISIQFLVYRRSTAASELEPLLPS
Sbjct: 246 GSYLLHHLPWLVGSLGVLLLDTIISIQFLVYRRSTAASELEPLLPS 291


>gi|92110025 PQ loop repeat containing 2 isoform 1 [Homo sapiens]
          Length = 291

 Score =  441 bits (1135), Expect = e-124
 Identities = 226/226 (100%), Positives = 226/226 (100%)

Query: 1   MDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLVMLTLYFYYKFRTRP 60
           MDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLVMLTLYFYYKFRTRP
Sbjct: 66  MDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLVMLTLYFYYKFRTRP 125

Query: 61  SLLSAPINSVLLFLMGMACATPLLSAAGPVAAPREAFRGRALLSVESGSKPFTRQEVIGF 120
           SLLSAPINSVLLFLMGMACATPLLSAAGPVAAPREAFRGRALLSVESGSKPFTRQEVIGF
Sbjct: 126 SLLSAPINSVLLFLMGMACATPLLSAAGPVAAPREAFRGRALLSVESGSKPFTRQEVIGF 185

Query: 121 VIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGLSVLLKNPEEGQSE 180
           VIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGLSVLLKNPEEGQSE
Sbjct: 186 VIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGLSVLLKNPEEGQSE 245

Query: 181 GSYLLHHLPWLVGSLGVLLLDTIISIQFLVYRRSTAASELEPLLPS 226
           GSYLLHHLPWLVGSLGVLLLDTIISIQFLVYRRSTAASELEPLLPS
Sbjct: 246 GSYLLHHLPWLVGSLGVLLLDTIISIQFLVYRRSTAASELEPLLPS 291


>gi|92110023 PQ loop repeat containing 2 isoform 2 [Homo sapiens]
          Length = 226

 Score =  441 bits (1135), Expect = e-124
 Identities = 226/226 (100%), Positives = 226/226 (100%)

Query: 1   MDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLVMLTLYFYYKFRTRP 60
           MDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLVMLTLYFYYKFRTRP
Sbjct: 1   MDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLVMLTLYFYYKFRTRP 60

Query: 61  SLLSAPINSVLLFLMGMACATPLLSAAGPVAAPREAFRGRALLSVESGSKPFTRQEVIGF 120
           SLLSAPINSVLLFLMGMACATPLLSAAGPVAAPREAFRGRALLSVESGSKPFTRQEVIGF
Sbjct: 61  SLLSAPINSVLLFLMGMACATPLLSAAGPVAAPREAFRGRALLSVESGSKPFTRQEVIGF 120

Query: 121 VIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGLSVLLKNPEEGQSE 180
           VIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGLSVLLKNPEEGQSE
Sbjct: 121 VIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGLSVLLKNPEEGQSE 180

Query: 181 GSYLLHHLPWLVGSLGVLLLDTIISIQFLVYRRSTAASELEPLLPS 226
           GSYLLHHLPWLVGSLGVLLLDTIISIQFLVYRRSTAASELEPLLPS
Sbjct: 181 GSYLLHHLPWLVGSLGVLLLDTIISIQFLVYRRSTAASELEPLLPS 226


>gi|194018508 hypothetical protein LOC152078 isoform 1 [Homo
           sapiens]
          Length = 135

 Score = 59.7 bits (143), Expect = 2e-09
 Identities = 32/88 (36%), Positives = 51/88 (57%), Gaps = 9/88 (10%)

Query: 1   MDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLVMLTLYFYYKFRT-- 58
           +D+A+SL FL  WIGGD  N  G +L +QLP+Q +TA++ +  D+++L+ + YY+ +   
Sbjct: 39  VDEAVSLGFLDCWIGGDLTNFKGCYLTNQLPIQIFTAIFDMNTDVIILSQFMYYRLKNQK 98

Query: 59  -----RPSLLSAPI--NSVLLFLMGMAC 79
                +P L    I    V L L G+ C
Sbjct: 99  KKMIFQPQLFKDSITREKVRLSLWGVLC 126


>gi|153791811 hypothetical protein LOC152078 isoform 3 [Homo
           sapiens]
          Length = 118

 Score = 59.7 bits (143), Expect = 2e-09
 Identities = 25/64 (39%), Positives = 44/64 (68%)

Query: 1   MDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLVMLTLYFYYKFRTRP 60
           +D+A+SL FL  WIGGD  N  G +L +QLP+Q +TA++ +  D+++L+ + YY+ + + 
Sbjct: 39  VDEAVSLGFLDCWIGGDLTNFKGCYLTNQLPIQIFTAIFDMNTDVIILSQFMYYRLKNQK 98

Query: 61  SLLS 64
             +S
Sbjct: 99  KKIS 102


>gi|58533182 transmembrane protein 44 isoform b [Homo sapiens]
          Length = 428

 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 52/197 (26%), Positives = 80/197 (40%), Gaps = 19/197 (9%)

Query: 19  CNLIGSFLADQLPLQTYTAVYYVLADLVMLTLYFY----YKFRTRPSLLSAPINSVLLFL 74
           C+ +G+ LA QL +Q +T  Y    DLV      +     KF++  S   A        L
Sbjct: 74  CDTVGALLARQLTIQVFTGAYLAAIDLVNFMFILFPVCGSKFKSN-SDREARERKRRRQL 132

Query: 75  MGMACATPLLSAAGP-----VAAPREAFRGRALLSVESGSKPFTRQEVIGFVIGSISSVL 129
                A  L  + GP     VA P+ +   R        S      E++G+++GS+++  
Sbjct: 133 RASVFALALPLSLGPCWALWVAVPKASATIRGPQRRLLASLLQENTEILGYLLGSVAAFG 192

Query: 130 YLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGLSVLL--KNPEEGQSEGSYLLHH 187
              SR+P +      K+   I      L  L   LY  +++   ++PE       YLL  
Sbjct: 193 SWASRIPPLSRICRGKTFPSIHLWTRLLSALAGLLYASAIVAHDQHPE-------YLLRA 245

Query: 188 LPWLVGSLGVLLLDTII 204
            PW + SLG   LD  I
Sbjct: 246 TPWFLTSLGRAALDLAI 262


>gi|38679902 transmembrane protein 44 isoform a [Homo sapiens]
          Length = 439

 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 52/197 (26%), Positives = 80/197 (40%), Gaps = 19/197 (9%)

Query: 19  CNLIGSFLADQLPLQTYTAVYYVLADLVMLTLYFY----YKFRTRPSLLSAPINSVLLFL 74
           C+ +G+ LA QL +Q +T  Y    DLV      +     KF++  S   A        L
Sbjct: 74  CDTVGALLARQLTIQVFTGAYLAAIDLVNFMFILFPVCGSKFKSN-SDREARERKRRRQL 132

Query: 75  MGMACATPLLSAAGP-----VAAPREAFRGRALLSVESGSKPFTRQEVIGFVIGSISSVL 129
                A  L  + GP     VA P+ +   R        S      E++G+++GS+++  
Sbjct: 133 RASVFALALPLSLGPCWALWVAVPKASATIRGPQRRLLASLLQENTEILGYLLGSVAAFG 192

Query: 130 YLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGLSVLL--KNPEEGQSEGSYLLHH 187
              SR+P +      K+   I      L  L   LY  +++   ++PE       YLL  
Sbjct: 193 SWASRIPPLSRICRGKTFPSIHLWTRLLSALAGLLYASAIVAHDQHPE-------YLLRA 245

Query: 188 LPWLVGSLGVLLLDTII 204
            PW + SLG   LD  I
Sbjct: 246 TPWFLTSLGRAALDLAI 262


>gi|194018506 hypothetical protein LOC152078 isoform 2 [Homo
          sapiens]
          Length = 133

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 18/33 (54%), Positives = 24/33 (72%)

Query: 1  MDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQ 33
          +D+A+SL FL  WIGGD  N  G +L +QLP+Q
Sbjct: 39 VDEAVSLGFLDCWIGGDLTNFKGCYLTNQLPIQ 71


>gi|119943110 cystinosis, nephropathic isoform 2 [Homo sapiens]
          Length = 367

 Score = 34.3 bits (77), Expect = 0.089
 Identities = 19/51 (37%), Positives = 28/51 (54%)

Query: 117 VIGFVIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGL 167
           +I  VIG I  V + +S  PQ+  N+ RKS  G+S+   AL + G   Y +
Sbjct: 125 IINQVIGWIYFVAWSISFYPQVIMNWRRKSVIGLSFDFVALNLTGFVAYSV 175



 Score = 28.1 bits (61), Expect = 6.4
 Identities = 30/104 (28%), Positives = 44/104 (42%), Gaps = 7/104 (6%)

Query: 120 FVIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGLSVLLKNPEEGQS 179
           F    I   + L+   PQ   NF  KST+G S     L   G +   L + L++    Q 
Sbjct: 267 FCFSYIKLAVTLVKYFPQAYMNFYYKSTEGWSIGNVLLDFTGGSFSLLQMFLQSYNNDQW 326

Query: 180 EGSYLLHHLPWLVGSLGV--LLLDTIISIQ-FLVYRRSTAASEL 220
               L+   P   G LGV  ++ D +  IQ F +YR+     +L
Sbjct: 327 T---LIFGDPTKFG-LGVFSIVFDVVFFIQHFCLYRKRPGYDQL 366


>gi|119943118 cystinosis, nephropathic isoform 1 [Homo sapiens]
          Length = 400

 Score = 34.3 bits (77), Expect = 0.089
 Identities = 19/51 (37%), Positives = 28/51 (54%)

Query: 117 VIGFVIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGL 167
           +I  VIG I  V + +S  PQ+  N+ RKS  G+S+   AL + G   Y +
Sbjct: 125 IINQVIGWIYFVAWSISFYPQVIMNWRRKSVIGLSFDFVALNLTGFVAYSV 175


>gi|45505167 immunoglobulin superfamily, member 1 isoform 1 [Homo
           sapiens]
          Length = 1336

 Score = 29.3 bits (64), Expect = 2.9
 Identities = 21/69 (30%), Positives = 31/69 (44%), Gaps = 10/69 (14%)

Query: 60  PSLLSAPINSVLLFLMGMACATPLLSAAGPVAAPREAFRGR----------ALLSVESGS 109
           P+L S P N + L + G+     L +  GP+ AP E+   R          AL+ VE   
Sbjct: 207 PTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLNLRCQGPIYGMTFALMRVEDLE 266

Query: 110 KPFTRQEVI 118
           K F  ++ I
Sbjct: 267 KSFYHKKTI 275


>gi|22027651 adaptor-related protein complex 1 beta 1 subunit
           isoform a [Homo sapiens]
          Length = 949

 Score = 29.3 bits (64), Expect = 2.9
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 8/83 (9%)

Query: 60  PSLLSAPINSVLLFLMGMACATPLLSAAGPVAAPREAFRGRALLSVESGSKPFTRQEVIG 119
           P+ L API S L  L  +      LS  G   AP+  +           S  FTRQ    
Sbjct: 688 PANLGAPIGSGLSDLFDLTSGVGTLS--GSYVAPKAVWLPAMKAKGLEISGTFTRQ---- 741

Query: 120 FVIGSISSVLYLLSRLPQIRTNF 142
             +GSIS  L L ++  Q+ T+F
Sbjct: 742 --VGSISMDLQLTNKALQVMTDF 762


>gi|22027653 adaptor-related protein complex 1 beta 1 subunit
           isoform b [Homo sapiens]
          Length = 942

 Score = 29.3 bits (64), Expect = 2.9
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 8/83 (9%)

Query: 60  PSLLSAPINSVLLFLMGMACATPLLSAAGPVAAPREAFRGRALLSVESGSKPFTRQEVIG 119
           P+ L API S L  L  +      LS  G   AP+  +           S  FTRQ    
Sbjct: 681 PANLGAPIGSGLSDLFDLTSGVGTLS--GSYVAPKAVWLPAMKAKGLEISGTFTRQ---- 734

Query: 120 FVIGSISSVLYLLSRLPQIRTNF 142
             +GSIS  L L ++  Q+ T+F
Sbjct: 735 --VGSISMDLQLTNKALQVMTDF 755


>gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens]
          Length = 568

 Score = 28.5 bits (62), Expect = 4.9
 Identities = 15/35 (42%), Positives = 25/35 (71%), Gaps = 3/35 (8%)

Query: 159 MLGNTLYGLSVLLKNPEEGQSEGSYLLHHLPWLVG 193
           +LG  + G+ +LLK PEE Q+E ++  H +P++VG
Sbjct: 319 LLGTVIDGM-LLLKTPEELQAERNF--HTVPYMVG 350


>gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens]
          Length = 567

 Score = 28.5 bits (62), Expect = 4.9
 Identities = 15/35 (42%), Positives = 25/35 (71%), Gaps = 3/35 (8%)

Query: 159 MLGNTLYGLSVLLKNPEEGQSEGSYLLHHLPWLVG 193
           +LG  + G+ +LLK PEE Q+E ++  H +P++VG
Sbjct: 318 LLGTVIDGM-LLLKTPEELQAERNF--HTVPYMVG 349


>gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens]
          Length = 566

 Score = 28.5 bits (62), Expect = 4.9
 Identities = 15/35 (42%), Positives = 25/35 (71%), Gaps = 3/35 (8%)

Query: 159 MLGNTLYGLSVLLKNPEEGQSEGSYLLHHLPWLVG 193
           +LG  + G+ +LLK PEE Q+E ++  H +P++VG
Sbjct: 318 LLGTVIDGM-LLLKTPEELQAERNF--HTVPYMVG 349


>gi|13491166 pumilio 1 isoform 2 [Homo sapiens]
          Length = 1186

 Score = 28.1 bits (61), Expect = 6.4
 Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 4/54 (7%)

Query: 57  RTRPSLLSAPINSVLLFLMGMACATPLLSAAGPVAAPREAFRGRALLSVESGSK 110
           +T P + +A +NS L F  G+A   P      PV AP   +     L V +G++
Sbjct: 523 QTDPLVAAAAVNSALAFGQGLAAGMP----GYPVLAPAAYYDQTGALVVNAGAR 572


>gi|66932909 pumilio 1 isoform 1 [Homo sapiens]
          Length = 1188

 Score = 28.1 bits (61), Expect = 6.4
 Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 4/54 (7%)

Query: 57  RTRPSLLSAPINSVLLFLMGMACATPLLSAAGPVAAPREAFRGRALLSVESGSK 110
           +T P + +A +NS L F  G+A   P      PV AP   +     L V +G++
Sbjct: 523 QTDPLVAAAAVNSALAFGQGLAAGMP----GYPVLAPAAYYDQTGALVVNAGAR 572


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.140    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,726,114
Number of Sequences: 37866
Number of extensions: 304107
Number of successful extensions: 1011
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 998
Number of HSP's gapped (non-prelim): 21
length of query: 226
length of database: 18,247,518
effective HSP length: 99
effective length of query: 127
effective length of database: 14,498,784
effective search space: 1841345568
effective search space used: 1841345568
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.