BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|90903238 glutathione peroxidase 4 isoform B precursor [Homo sapiens] (227 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|90903238 glutathione peroxidase 4 isoform B precursor [Homo s... 479 e-136 gi|75709200 glutathione peroxidase 4 isoform A precursor [Homo s... 355 2e-98 gi|90903240 glutathione peroxidase 4 isoform C precursor [Homo s... 300 7e-82 gi|15618997 glutathione peroxidase 7 [Homo sapiens] 108 5e-24 gi|192455698 glutathione peroxidase 8 [Homo sapiens] 94 7e-20 gi|41406084 glutathione peroxidase 1 isoform 1 [Homo sapiens] 89 4e-18 gi|32967607 glutathione peroxidase 2 [Homo sapiens] 82 4e-16 gi|6006001 glutathione peroxidase 3 precursor [Homo sapiens] 77 9e-15 gi|33186887 glutathione peroxidase 6 [Homo sapiens] 67 1e-11 gi|4557629 glutathione peroxidase 5 isoform 1 precursor [Homo sa... 67 2e-11 gi|41406082 glutathione peroxidase 1 isoform 2 [Homo sapiens] 62 4e-10 gi|195539337 S-adenosylhomocysteine hydrolase-like 2 isoform b [... 28 4.9 gi|24308043 S-adenosylhomocysteine hydrolase-like 2 isoform a [H... 28 4.9 gi|169210434 PREDICTED: hypothetical protein [Homo sapiens] 28 6.4 gi|34452173 integrin alpha X precursor [Homo sapiens] 28 6.4 gi|194018443 potassium channel tetramerisation domain containing... 28 6.4 gi|194018441 potassium channel tetramerisation domain containing... 28 6.4 gi|194018439 potassium channel tetramerisation domain containing... 28 6.4 gi|16945972 kelch domain containing 3 [Homo sapiens] 28 6.4 gi|66472382 nischarin [Homo sapiens] 28 8.4 >gi|90903238 glutathione peroxidase 4 isoform B precursor [Homo sapiens] Length = 227 Score = 479 bits (1233), Expect = e-136 Identities = 227/227 (100%), Positives = 227/227 (100%) Query: 1 MSLGRLCRLLKPALLCGALAAPGLAGTMCASRDDWRCARSMHEFSAKDIDGHMVNLDKYR 60 MSLGRLCRLLKPALLCGALAAPGLAGTMCASRDDWRCARSMHEFSAKDIDGHMVNLDKYR Sbjct: 1 MSLGRLCRLLKPALLCGALAAPGLAGTMCASRDDWRCARSMHEFSAKDIDGHMVNLDKYR 60 Query: 61 GFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILAFPCNQFGKQEPGSNEEIKEFA 120 GFVCIVTNVASQ GKTEVNYTQLVDLHARYAECGLRILAFPCNQFGKQEPGSNEEIKEFA Sbjct: 61 GFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILAFPCNQFGKQEPGSNEEIKEFA 120 Query: 121 AGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILGNAIKWNFTKFGHRLSTVPHRQE 180 AGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILGNAIKWNFTKFGHRLSTVPHRQE Sbjct: 121 AGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILGNAIKWNFTKFGHRLSTVPHRQE 180 Query: 181 RLRGEALRTHGGAPGDREGPAPLFLAPQVCGPARAPAHALGAFHRHS 227 RLRGEALRTHGGAPGDREGPAPLFLAPQVCGPARAPAHALGAFHRHS Sbjct: 181 RLRGEALRTHGGAPGDREGPAPLFLAPQVCGPARAPAHALGAFHRHS 227 >gi|75709200 glutathione peroxidase 4 isoform A precursor [Homo sapiens] Length = 197 Score = 355 bits (910), Expect = 2e-98 Identities = 168/168 (100%), Positives = 168/168 (100%) Query: 1 MSLGRLCRLLKPALLCGALAAPGLAGTMCASRDDWRCARSMHEFSAKDIDGHMVNLDKYR 60 MSLGRLCRLLKPALLCGALAAPGLAGTMCASRDDWRCARSMHEFSAKDIDGHMVNLDKYR Sbjct: 1 MSLGRLCRLLKPALLCGALAAPGLAGTMCASRDDWRCARSMHEFSAKDIDGHMVNLDKYR 60 Query: 61 GFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILAFPCNQFGKQEPGSNEEIKEFA 120 GFVCIVTNVASQ GKTEVNYTQLVDLHARYAECGLRILAFPCNQFGKQEPGSNEEIKEFA Sbjct: 61 GFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILAFPCNQFGKQEPGSNEEIKEFA 120 Query: 121 AGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILGNAIKWNFTKF 168 AGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILGNAIKWNFTKF Sbjct: 121 AGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILGNAIKWNFTKF 168 >gi|90903240 glutathione peroxidase 4 isoform C precursor [Homo sapiens] Length = 234 Score = 300 bits (768), Expect = 7e-82 Identities = 140/140 (100%), Positives = 140/140 (100%) Query: 29 CASRDDWRCARSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHA 88 CASRDDWRCARSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQ GKTEVNYTQLVDLHA Sbjct: 66 CASRDDWRCARSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHA 125 Query: 89 RYAECGLRILAFPCNQFGKQEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMK 148 RYAECGLRILAFPCNQFGKQEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMK Sbjct: 126 RYAECGLRILAFPCNQFGKQEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMK 185 Query: 149 IQPKGKGILGNAIKWNFTKF 168 IQPKGKGILGNAIKWNFTKF Sbjct: 186 IQPKGKGILGNAIKWNFTKF 205 >gi|15618997 glutathione peroxidase 7 [Homo sapiens] Length = 187 Score = 108 bits (269), Expect = 5e-24 Identities = 60/131 (45%), Positives = 80/131 (61%), Gaps = 7/131 (5%) Query: 39 RSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRIL 98 + ++F A +I G +V+L+KYRG V +V NVAS+ G T+ +Y L L +L Sbjct: 23 QDFYDFKAVNIRGKLVSLEKYRGSVSLVVNVASECGFTDQHYRALQQLQRDLGPHHFNVL 82 Query: 99 AFPCNQFGKQEPGSNEEIKEFA-AGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGIL 157 AFPCNQFG+QEP SN+EI+ FA Y+V F MFSKI V G AHP +K++ Q GK Sbjct: 83 AFPCNQFGQQEPDSNKEIESFARRTYSVSFPMFSKIAVTGTGAHPAFKYL-AQTSGK--- 138 Query: 158 GNAIKWNFTKF 168 WNF K+ Sbjct: 139 --EPTWNFWKY 147 >gi|192455698 glutathione peroxidase 8 [Homo sapiens] Length = 209 Score = 94.4 bits (233), Expect = 7e-20 Identities = 49/130 (37%), Positives = 73/130 (56%), Gaps = 7/130 (5%) Query: 40 SMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILA 99 S + F KD G V+L+KY+G V +V NVAS T+ NY L +LH + +LA Sbjct: 46 SFYAFEVKDAKGRTVSLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLA 105 Query: 100 FPCNQFGKQEPGSNEEIKEFA-AGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILG 158 FPCNQFG+ EP ++E++ FA Y V F +F KI + G + P ++++ K + Sbjct: 106 FPCNQFGESEPRPSKEVESFARKNYGVTFPIFHKIKILGSEGEPAFRFLVDSSKKEP--- 162 Query: 159 NAIKWNFTKF 168 +WNF K+ Sbjct: 163 ---RWNFWKY 169 >gi|41406084 glutathione peroxidase 1 isoform 1 [Homo sapiens] Length = 203 Score = 88.6 bits (218), Expect = 4e-18 Identities = 66/186 (35%), Positives = 90/186 (48%), Gaps = 26/186 (13%) Query: 28 MCASR--DDWRCARSMHEFSAKDI-DGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLV 84 MCA+R A+S++ FSA+ + G V+L RG V ++ NVAS G T +YTQ+ Sbjct: 1 MCAARLAAAAAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYTQMN 60 Query: 85 DLHARYAECGLRILAFPCNQFGKQEPGSNEEIKEF------AAGYNVKFDMFSKICVNGD 138 +L R GL +L FPCNQFG QE NEEI G+ F +F K VNG Sbjct: 61 ELQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGA 120 Query: 139 DAHPLWKWMK--------------IQPK---GKGILGNAIKWNFTKFGHRLSTVPHRQER 181 AHPL+ +++ PK + N + WNF KF VP R+ Sbjct: 121 GAHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYS 180 Query: 182 LRGEAL 187 R + + Sbjct: 181 RRFQTI 186 >gi|32967607 glutathione peroxidase 2 [Homo sapiens] Length = 190 Score = 82.0 bits (201), Expect = 4e-16 Identities = 53/154 (34%), Positives = 78/154 (50%), Gaps = 24/154 (15%) Query: 38 ARSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRI 97 A+S ++ SA +DG V+ + +RG ++ NVAS G T ++TQL +L R+ L + Sbjct: 5 AKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPR-RLVV 63 Query: 98 LAFPCNQFGKQEPGSNEEIKEF------AAGYNVKFDMFSKICVNGDDAHPLWKWMK--- 148 L FPCNQFG QE NEEI GY F + K VNG + HP++ ++K Sbjct: 64 LGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKDKL 123 Query: 149 ---------IQPKGKGILGNAIK-----WNFTKF 168 + K I+ + ++ WNF KF Sbjct: 124 PYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKF 157 >gi|6006001 glutathione peroxidase 3 precursor [Homo sapiens] Length = 226 Score = 77.4 bits (189), Expect = 9e-15 Identities = 61/187 (32%), Positives = 86/187 (45%), Gaps = 25/187 (13%) Query: 6 LCRLLKPALLCGALAAPGLAGTMCASRDDWRC----ARSMHEFSAKDIDGH-MVNLDKYR 60 + RLL+ + L L A ++ + + C + +++E+ A IDG + +Y Sbjct: 1 MARLLQASCLLSLLLAGFVSQSRGQEKSKMDCHGGISGTIYEYGALTIDGEEYIPFKQYA 60 Query: 61 GFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILAFPCNQFGKQEPGSNEEIKEF- 119 G + NVAS G T Y +L L A GL IL FPCNQFGKQEPG N EI Sbjct: 61 GKYVLFVNVASYUGLTG-QYIELNALQEELAPFGLVILGFPCNQFGKQEPGENSEILPTL 119 Query: 120 -----AAGYNVKFDMFSKICVNGDDAHPLWKWMKIQ-PKGKGILGNA------------I 161 G+ F +F K VNG+ + ++K P +LG + I Sbjct: 120 KYVRPGGGFVPNFQLFEKGDVNGEKEQKFYTFLKNSCPPTSELLGTSDRLFWEPMKVHDI 179 Query: 162 KWNFTKF 168 +WNF KF Sbjct: 180 RWNFEKF 186 >gi|33186887 glutathione peroxidase 6 [Homo sapiens] Length = 221 Score = 67.4 bits (163), Expect = 1e-11 Identities = 47/149 (31%), Positives = 74/149 (49%), Gaps = 21/149 (14%) Query: 40 SMHEFSAKDIDGH-MVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRIL 98 +++E+ A ++G + ++ G + NVA+ G Y +L L G+ +L Sbjct: 39 TIYEYGALTLNGEEYIQFKQFAGKHVLFVNVAAYUGLA-AQYPELNALQEELKNFGVIVL 97 Query: 99 AFPCNQFGKQEPGSNEEIKEF------AAGYNVKFDMFSKICVNGDDAHPLWKWMKIQ-P 151 AFPCNQFGKQEPG+N EI +G+ F +F K VNG+ ++ ++K P Sbjct: 98 AFPCNQFGKQEPGTNSEILLGLKYVCPGSGFVPSFQLFEKGDVNGEKEQKVFTFLKNSCP 157 Query: 152 KGKGILGNA------------IKWNFTKF 168 +LG++ I+WNF KF Sbjct: 158 PTSDLLGSSSQLFWEPMKVHDIRWNFEKF 186 >gi|4557629 glutathione peroxidase 5 isoform 1 precursor [Homo sapiens] Length = 221 Score = 66.6 bits (161), Expect = 2e-11 Identities = 47/134 (35%), Positives = 63/134 (47%), Gaps = 20/134 (14%) Query: 54 VNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILAFPCNQFGKQEPGSN 113 V+ +Y G + NVA+ G T Y +L L GL +L FPCNQFGKQEPG N Sbjct: 54 VSFKQYVGKHILFVNVATYCGLT-AQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDN 112 Query: 114 EEI------KEFAAGYNVKFDMFSKICVNGDDAHPLWKWMKIQ-PKGKGILG-------- 158 +EI G+ F +F K VNG+ ++ ++K P ILG Sbjct: 113 KEILPGLKYVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWD 172 Query: 159 ----NAIKWNFTKF 168 + I+WNF KF Sbjct: 173 PVKVHDIRWNFEKF 186 >gi|41406082 glutathione peroxidase 1 isoform 2 [Homo sapiens] Length = 98 Score = 62.0 bits (149), Expect = 4e-10 Identities = 38/84 (45%), Positives = 51/84 (60%), Gaps = 3/84 (3%) Query: 28 MCASR--DDWRCARSMHEFSAKDI-DGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLV 84 MCA+R A+S++ FSA+ + G V+L RG V ++ NVAS G T +YTQ+ Sbjct: 1 MCAARLAAAAAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYTQMN 60 Query: 85 DLHARYAECGLRILAFPCNQFGKQ 108 +L R GL +L FPCNQFG Q Sbjct: 61 ELQRRLGPRGLVVLGFPCNQFGHQ 84 >gi|195539337 S-adenosylhomocysteine hydrolase-like 2 isoform b [Homo sapiens] Length = 610 Score = 28.5 bits (62), Expect = 4.9 Identities = 14/26 (53%), Positives = 14/26 (53%) Query: 195 GDREGPAPLFLAPQVCGPARAPAHAL 220 GD E PAP P V GP PA AL Sbjct: 48 GDPEAPAPAAERPPVPGPGSGPAAAL 73 >gi|24308043 S-adenosylhomocysteine hydrolase-like 2 isoform a [Homo sapiens] Length = 611 Score = 28.5 bits (62), Expect = 4.9 Identities = 14/26 (53%), Positives = 14/26 (53%) Query: 195 GDREGPAPLFLAPQVCGPARAPAHAL 220 GD E PAP P V GP PA AL Sbjct: 48 GDPEAPAPAAERPPVPGPGSGPAAAL 73 >gi|169210434 PREDICTED: hypothetical protein [Homo sapiens] Length = 301 Score = 28.1 bits (61), Expect = 6.4 Identities = 15/31 (48%), Positives = 16/31 (51%), Gaps = 2/31 (6%) Query: 188 RTHGGAPGD--REGPAPLFLAPQVCGPARAP 216 R G G+ R GPAP L P VC RAP Sbjct: 107 RAQKGGKGEETRRGPAPAGLTPSVCLYGRAP 137 >gi|34452173 integrin alpha X precursor [Homo sapiens] Length = 1163 Score = 28.1 bits (61), Expect = 6.4 Identities = 11/28 (39%), Positives = 18/28 (64%) Query: 192 GAPGDREGPAPLFLAPQVCGPARAPAHA 219 GAPG+ E ++L V GP+ +P+H+ Sbjct: 542 GAPGEEENRGAVYLFHGVLGPSISPSHS 569 >gi|194018443 potassium channel tetramerisation domain containing 15 isoform 2 [Homo sapiens] Length = 283 Score = 28.1 bits (61), Expect = 6.4 Identities = 13/25 (52%), Positives = 17/25 (68%), Gaps = 1/25 (4%) Query: 175 VPHRQERLRGEALRTHGGAPGDREG 199 +PHR+ER G +L TH G+ G EG Sbjct: 1 MPHRKERPSGSSLHTH-GSTGTAEG 24 >gi|194018441 potassium channel tetramerisation domain containing 15 isoform 2 [Homo sapiens] Length = 283 Score = 28.1 bits (61), Expect = 6.4 Identities = 13/25 (52%), Positives = 17/25 (68%), Gaps = 1/25 (4%) Query: 175 VPHRQERLRGEALRTHGGAPGDREG 199 +PHR+ER G +L TH G+ G EG Sbjct: 1 MPHRKERPSGSSLHTH-GSTGTAEG 24 >gi|194018439 potassium channel tetramerisation domain containing 15 isoform 1 [Homo sapiens] Length = 234 Score = 28.1 bits (61), Expect = 6.4 Identities = 13/25 (52%), Positives = 17/25 (68%), Gaps = 1/25 (4%) Query: 175 VPHRQERLRGEALRTHGGAPGDREG 199 +PHR+ER G +L TH G+ G EG Sbjct: 1 MPHRKERPSGSSLHTH-GSTGTAEG 24 >gi|16945972 kelch domain containing 3 [Homo sapiens] Length = 382 Score = 28.1 bits (61), Expect = 6.4 Identities = 19/52 (36%), Positives = 23/52 (44%), Gaps = 17/52 (32%) Query: 111 GSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWK-------WMKIQPKGKG 155 G N E+ F GYN + + H LWK W KI+PKGKG Sbjct: 246 GYNGELYIFG-GYNARLNRHF---------HDLWKFNPVSFTWKKIEPKGKG 287 >gi|66472382 nischarin [Homo sapiens] Length = 1504 Score = 27.7 bits (60), Expect = 8.4 Identities = 18/49 (36%), Positives = 23/49 (46%), Gaps = 5/49 (10%) Query: 171 RLSTVPHRQERLRGEALRTHGGAPGDREGPAPLFLAPQVCGPARAPAHA 219 R ++ R + + EAL AP E PAP A GPA+ PA A Sbjct: 1035 RRASNDQRPQEVPAEAL-----APAPAEVPAPAPAAASASGPAKTPAPA 1078 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.323 0.139 0.453 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,959,284 Number of Sequences: 37866 Number of extensions: 461576 Number of successful extensions: 1015 Number of sequences better than 10.0: 20 Number of HSP's better than 10.0 without gapping: 14 Number of HSP's successfully gapped in prelim test: 6 Number of HSP's that attempted gapping in prelim test: 994 Number of HSP's gapped (non-prelim): 21 length of query: 227 length of database: 18,247,518 effective HSP length: 99 effective length of query: 128 effective length of database: 14,498,784 effective search space: 1855844352 effective search space used: 1855844352 T: 11 A: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.