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Search of human proteins with 90669228
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|90669228 deleted in lung and esophageal cancer 1 isoform
DLEC1-S3 [Homo sapiens]
(1778 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|90669228 deleted in lung and esophageal cancer 1 isoform DLEC... 3611 0.0
gi|90669194 deleted in lung and esophageal cancer 1 isoform DLEC... 3382 0.0
gi|119703749 hydrocephalus inducing isoform a [Homo sapiens] 118 4e-26
gi|46361983 hydrocephalus inducing isoform b [Homo sapiens] 118 4e-26
gi|122937416 hypothetical protein LOC85452 [Homo sapiens] 44 0.001
gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo sa... 39 0.059
gi|21735548 centrosomal protein 2 [Homo sapiens] 38 0.077
gi|169217799 PREDICTED: hypothetical protein [Homo sapiens] 37 0.17
gi|239752508 PREDICTED: hypothetical protein XP_002347011 [Homo ... 37 0.17
gi|239743770 PREDICTED: hypothetical protein XP_002342956 [Homo ... 37 0.17
gi|58331242 formin homology 2 domain containing 3 [Homo sapiens] 35 0.50
gi|33946313 ninein isoform 4 [Homo sapiens] 35 0.50
gi|33946321 ninein isoform 5 [Homo sapiens] 35 0.50
gi|148536871 ninein isoform 1 [Homo sapiens] 35 0.50
gi|148536869 ninein isoform 2 [Homo sapiens] 35 0.50
gi|90963001 hypothetical protein LOC170063 [Homo sapiens] 34 1.1
gi|4557719 DNA ligase I [Homo sapiens] 33 2.5
gi|239756270 PREDICTED: StAR-related lipid transfer (START) doma... 33 3.2
gi|239750815 PREDICTED: StAR-related lipid transfer (START) doma... 33 3.2
gi|239745175 PREDICTED: StAR-related lipid transfer (START) doma... 33 3.2
gi|24234690 meiotic recombination 11 homolog A isoform 2 [Homo s... 32 4.2
gi|5031923 meiotic recombination 11 homolog A isoform 1 [Homo sa... 32 4.2
gi|8394499 ubiquitin associated protein 1 [Homo sapiens] 32 4.2
gi|4758822 nephrin precursor [Homo sapiens] 32 4.2
gi|47578115 DEP domain containing 2 isoform a [Homo sapiens] 32 4.2
gi|50811889 centrosomal protein 192kDa [Homo sapiens] 32 4.2
gi|153946403 BCL2/adenovirus E1B 19kD interacting protein 1 isof... 32 4.2
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens] 32 5.5
gi|46370057 ring finger protein 216 isoform b [Homo sapiens] 32 5.5
gi|46358403 ring finger protein 216 isoform a [Homo sapiens] 32 5.5
>gi|90669228 deleted in lung and esophageal cancer 1 isoform DLEC1-S3
[Homo sapiens]
Length = 1778
Score = 3611 bits (9364), Expect = 0.0
Identities = 1778/1778 (100%), Positives = 1778/1778 (100%)
Query: 1 METRSSKTRRSLASRTNECQGTMWAPTSPPAGSSSPSQPTWKSSLYSSLAYSEAFHYSFA 60
METRSSKTRRSLASRTNECQGTMWAPTSPPAGSSSPSQPTWKSSLYSSLAYSEAFHYSFA
Sbjct: 1 METRSSKTRRSLASRTNECQGTMWAPTSPPAGSSSPSQPTWKSSLYSSLAYSEAFHYSFA 60
Query: 61 ARPRRLTQLALAQRPEPQLLRLRPSSLRTQDISHLLTGVFRNLYSAEVIGDEVSASLIKA 120
ARPRRLTQLALAQRPEPQLLRLRPSSLRTQDISHLLTGVFRNLYSAEVIGDEVSASLIKA
Sbjct: 61 ARPRRLTQLALAQRPEPQLLRLRPSSLRTQDISHLLTGVFRNLYSAEVIGDEVSASLIKA 120
Query: 121 RGSENERHEEFVDQLQQIRELYKQRLDEFEMLERHITQAQARAIAENERVMSQAGVQDLE 180
RGSENERHEEFVDQLQQIRELYKQRLDEFEMLERHITQAQARAIAENERVMSQAGVQDLE
Sbjct: 121 RGSENERHEEFVDQLQQIRELYKQRLDEFEMLERHITQAQARAIAENERVMSQAGVQDLE 180
Query: 181 SLVRLPPVKSVSRWCIDSELLRKHHLISPEDYYTDTVPFHSAPKGISLPGCSKLTFSCEK 240
SLVRLPPVKSVSRWCIDSELLRKHHLISPEDYYTDTVPFHSAPKGISLPGCSKLTFSCEK
Sbjct: 181 SLVRLPPVKSVSRWCIDSELLRKHHLISPEDYYTDTVPFHSAPKGISLPGCSKLTFSCEK 240
Query: 241 RSVQKKELNKKLEDSCRKKLAEFEDELDHTVDSLTWNLTPKAKERTREPLKKASQPRNKN 300
RSVQKKELNKKLEDSCRKKLAEFEDELDHTVDSLTWNLTPKAKERTREPLKKASQPRNKN
Sbjct: 241 RSVQKKELNKKLEDSCRKKLAEFEDELDHTVDSLTWNLTPKAKERTREPLKKASQPRNKN 300
Query: 301 WMNHLRVPQRELDRLLLARMESRNHFLKNPRFFPPNTRYGGKSLVFPPKKPAPIGEFQST 360
WMNHLRVPQRELDRLLLARMESRNHFLKNPRFFPPNTRYGGKSLVFPPKKPAPIGEFQST
Sbjct: 301 WMNHLRVPQRELDRLLLARMESRNHFLKNPRFFPPNTRYGGKSLVFPPKKPAPIGEFQST 360
Query: 361 EPEQSCADTPVFLAKPPIGFFTDYEIGPVYEMVIALQNTTTTSRYLRVLPPSTPYFALGL 420
EPEQSCADTPVFLAKPPIGFFTDYEIGPVYEMVIALQNTTTTSRYLRVLPPSTPYFALGL
Sbjct: 361 EPEQSCADTPVFLAKPPIGFFTDYEIGPVYEMVIALQNTTTTSRYLRVLPPSTPYFALGL 420
Query: 421 GMFPGKGGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLS 480
GMFPGKGGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLS
Sbjct: 421 GMFPGKGGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLS 480
Query: 481 PVLDCGYCLIGGVKMTRFICKNVGFSVGRFCIMPKTSWPPLSFKAIATVGFVEQPPFGIL 540
PVLDCGYCLIGGVKMTRFICKNVGFSVGRFCIMPKTSWPPLSFKAIATVGFVEQPPFGIL
Sbjct: 481 PVLDCGYCLIGGVKMTRFICKNVGFSVGRFCIMPKTSWPPLSFKAIATVGFVEQPPFGIL 540
Query: 541 PSVFELAPGHAILVEVLFSPKSLGKAEQTFIIMCDNCQIKELVTIGIGQLIALDLIYISG 600
PSVFELAPGHAILVEVLFSPKSLGKAEQTFIIMCDNCQIKELVTIGIGQLIALDLIYISG
Sbjct: 541 PSVFELAPGHAILVEVLFSPKSLGKAEQTFIIMCDNCQIKELVTIGIGQLIALDLIYISG 600
Query: 601 EKSQPDPGELTDLTAQHFIRFEPENLRSTARKQLIIRNATHVELAFYWQIMKPNLQPLMP 660
EKSQPDPGELTDLTAQHFIRFEPENLRSTARKQLIIRNATHVELAFYWQIMKPNLQPLMP
Sbjct: 601 EKSQPDPGELTDLTAQHFIRFEPENLRSTARKQLIIRNATHVELAFYWQIMKPNLQPLMP 660
Query: 661 GETFSMDSIKCYPDKETAFSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVLEEVP 720
GETFSMDSIKCYPDKETAFSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVLEEVP
Sbjct: 661 GETFSMDSIKCYPDKETAFSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVLEEVP 720
Query: 721 EPVSSEAESLGHSSYSVDDVIVLEIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKAFK 780
EPVSSEAESLGHSSYSVDDVIVLEIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKAFK
Sbjct: 721 EPVSSEAESLGHSSYSVDDVIVLEIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKAFK 780
Query: 781 MWNNSKSPIRYLWGKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIE 840
MWNNSKSPIRYLWGKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIE
Sbjct: 781 MWNNSKSPIRYLWGKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIE 840
Query: 841 DSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPV 900
DSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPV
Sbjct: 841 DSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPV 900
Query: 901 SLQERPEDVSPFDIEPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLPVY 960
SLQERPEDVSPFDIEPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLPVY
Sbjct: 901 SLQERPEDVSPFDIEPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLPVY 960
Query: 961 AEVQKPHVYLQSSQVEVRNLYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEFCMVTVS 1020
AEVQKPHVYLQSSQVEVRNLYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEFCMVTVS
Sbjct: 961 AEVQKPHVYLQSSQVEVRNLYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEFCMVTVS 1020
Query: 1021 PKHGLLGPSEECQLKLELTAHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITIS 1080
PKHGLLGPSEECQLKLELTAHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITIS
Sbjct: 1021 PKHGLLGPSEECQLKLELTAHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITIS 1080
Query: 1081 KESSDCSTEQWPGHPKELRLDFGSAVPLRTRVTRQLILTNRSPIRTRFSLKFEYFGSPQN 1140
KESSDCSTEQWPGHPKELRLDFGSAVPLRTRVTRQLILTNRSPIRTRFSLKFEYFGSPQN
Sbjct: 1081 KESSDCSTEQWPGHPKELRLDFGSAVPLRTRVTRQLILTNRSPIRTRFSLKFEYFGSPQN 1140
Query: 1141 SLSKKTSLPNMPPALLKTVRMQEHLAKREQLDFMESMLSHGKGAAFFPHFSQGMLGPYQQ 1200
SLSKKTSLPNMPPALLKTVRMQEHLAKREQLDFMESMLSHGKGAAFFPHFSQGMLGPYQQ
Sbjct: 1141 SLSKKTSLPNMPPALLKTVRMQEHLAKREQLDFMESMLSHGKGAAFFPHFSQGMLGPYQQ 1200
Query: 1201 LCIDITGCANMWGEYWDNLICTVGDLLPEVIPVHMAAVGCPISSLRTTSYTIDQAQKEPA 1260
LCIDITGCANMWGEYWDNLICTVGDLLPEVIPVHMAAVGCPISSLRTTSYTIDQAQKEPA
Sbjct: 1201 LCIDITGCANMWGEYWDNLICTVGDLLPEVIPVHMAAVGCPISSLRTTSYTIDQAQKEPA 1260
Query: 1261 MRFGTQVSGGDTVTRTLRLNNSSPCDIRLDWETYVPEDKEDRLVELLVFYGPPFPLRDQA 1320
MRFGTQVSGGDTVTRTLRLNNSSPCDIRLDWETYVPEDKEDRLVELLVFYGPPFPLRDQA
Sbjct: 1261 MRFGTQVSGGDTVTRTLRLNNSSPCDIRLDWETYVPEDKEDRLVELLVFYGPPFPLRDQA 1320
Query: 1321 GNELVCPDTPEGGCLLWSPGPSSSSEFSHETDSSVEGSSSASNRVAQKLISVILQAHEGV 1380
GNELVCPDTPEGGCLLWSPGPSSSSEFSHETDSSVEGSSSASNRVAQKLISVILQAHEGV
Sbjct: 1321 GNELVCPDTPEGGCLLWSPGPSSSSEFSHETDSSVEGSSSASNRVAQKLISVILQAHEGV 1380
Query: 1381 PSGHLYCISPKQVVVPAGGSSTIYISFTPMVLSPEILHKVECTGYALGFMSLDSKVEREI 1440
PSGHLYCISPKQVVVPAGGSSTIYISFTPMVLSPEILHKVECTGYALGFMSLDSKVEREI
Sbjct: 1381 PSGHLYCISPKQVVVPAGGSSTIYISFTPMVLSPEILHKVECTGYALGFMSLDSKVEREI 1440
Query: 1441 PGKRHRLQDFAVGPLKLDLHSYVRPAQLSVELDYGGSMEFQCQASDLIPEQPCSGVLSEL 1500
PGKRHRLQDFAVGPLKLDLHSYVRPAQLSVELDYGGSMEFQCQASDLIPEQPCSGVLSEL
Sbjct: 1441 PGKRHRLQDFAVGPLKLDLHSYVRPAQLSVELDYGGSMEFQCQASDLIPEQPCSGVLSEL 1500
Query: 1501 VTTHHLKLTNTTEIPHYFRLMVSRPFSVSQDGASQDHRAPGPGQKQECEEETASADKQLV 1560
VTTHHLKLTNTTEIPHYFRLMVSRPFSVSQDGASQDHRAPGPGQKQECEEETASADKQLV
Sbjct: 1501 VTTHHLKLTNTTEIPHYFRLMVSRPFSVSQDGASQDHRAPGPGQKQECEEETASADKQLV 1560
Query: 1561 LQAQENMLVNVSFSLSLELLSYQKLPADQTLPGVDIQQSASGEREMVFTQNLLLEYTNQT 1620
LQAQENMLVNVSFSLSLELLSYQKLPADQTLPGVDIQQSASGEREMVFTQNLLLEYTNQT
Sbjct: 1561 LQAQENMLVNVSFSLSLELLSYQKLPADQTLPGVDIQQSASGEREMVFTQNLLLEYTNQT 1620
Query: 1621 TQVVPLRAVVAVPELQLSTSWVDFGTCFVSQQRVREVYLMNLSGCRSYWTMLMGVVSCTS 1680
TQVVPLRAVVAVPELQLSTSWVDFGTCFVSQQRVREVYLMNLSGCRSYWTMLMGVVSCTS
Sbjct: 1621 TQVVPLRAVVAVPELQLSTSWVDFGTCFVSQQRVREVYLMNLSGCRSYWTMLMGVVSCTS 1680
Query: 1681 PRWWWKVCSVRSPAPCGSGAKAPMMRDTCCLTSPEAPPQPSAPGPSWRKNIAQGLGAALQ 1740
PRWWWKVCSVRSPAPCGSGAKAPMMRDTCCLTSPEAPPQPSAPGPSWRKNIAQGLGAALQ
Sbjct: 1681 PRWWWKVCSVRSPAPCGSGAKAPMMRDTCCLTSPEAPPQPSAPGPSWRKNIAQGLGAALQ 1740
Query: 1741 HKDTDLGTWGPLGSSWNGRTPFHNGLSLGPHDMSSELT 1778
HKDTDLGTWGPLGSSWNGRTPFHNGLSLGPHDMSSELT
Sbjct: 1741 HKDTDLGTWGPLGSSWNGRTPFHNGLSLGPHDMSSELT 1778
>gi|90669194 deleted in lung and esophageal cancer 1 isoform DLEC1-N1
[Homo sapiens]
Length = 1755
Score = 3382 bits (8768), Expect = 0.0
Identities = 1674/1674 (100%), Positives = 1674/1674 (100%)
Query: 1 METRSSKTRRSLASRTNECQGTMWAPTSPPAGSSSPSQPTWKSSLYSSLAYSEAFHYSFA 60
METRSSKTRRSLASRTNECQGTMWAPTSPPAGSSSPSQPTWKSSLYSSLAYSEAFHYSFA
Sbjct: 1 METRSSKTRRSLASRTNECQGTMWAPTSPPAGSSSPSQPTWKSSLYSSLAYSEAFHYSFA 60
Query: 61 ARPRRLTQLALAQRPEPQLLRLRPSSLRTQDISHLLTGVFRNLYSAEVIGDEVSASLIKA 120
ARPRRLTQLALAQRPEPQLLRLRPSSLRTQDISHLLTGVFRNLYSAEVIGDEVSASLIKA
Sbjct: 61 ARPRRLTQLALAQRPEPQLLRLRPSSLRTQDISHLLTGVFRNLYSAEVIGDEVSASLIKA 120
Query: 121 RGSENERHEEFVDQLQQIRELYKQRLDEFEMLERHITQAQARAIAENERVMSQAGVQDLE 180
RGSENERHEEFVDQLQQIRELYKQRLDEFEMLERHITQAQARAIAENERVMSQAGVQDLE
Sbjct: 121 RGSENERHEEFVDQLQQIRELYKQRLDEFEMLERHITQAQARAIAENERVMSQAGVQDLE 180
Query: 181 SLVRLPPVKSVSRWCIDSELLRKHHLISPEDYYTDTVPFHSAPKGISLPGCSKLTFSCEK 240
SLVRLPPVKSVSRWCIDSELLRKHHLISPEDYYTDTVPFHSAPKGISLPGCSKLTFSCEK
Sbjct: 181 SLVRLPPVKSVSRWCIDSELLRKHHLISPEDYYTDTVPFHSAPKGISLPGCSKLTFSCEK 240
Query: 241 RSVQKKELNKKLEDSCRKKLAEFEDELDHTVDSLTWNLTPKAKERTREPLKKASQPRNKN 300
RSVQKKELNKKLEDSCRKKLAEFEDELDHTVDSLTWNLTPKAKERTREPLKKASQPRNKN
Sbjct: 241 RSVQKKELNKKLEDSCRKKLAEFEDELDHTVDSLTWNLTPKAKERTREPLKKASQPRNKN 300
Query: 301 WMNHLRVPQRELDRLLLARMESRNHFLKNPRFFPPNTRYGGKSLVFPPKKPAPIGEFQST 360
WMNHLRVPQRELDRLLLARMESRNHFLKNPRFFPPNTRYGGKSLVFPPKKPAPIGEFQST
Sbjct: 301 WMNHLRVPQRELDRLLLARMESRNHFLKNPRFFPPNTRYGGKSLVFPPKKPAPIGEFQST 360
Query: 361 EPEQSCADTPVFLAKPPIGFFTDYEIGPVYEMVIALQNTTTTSRYLRVLPPSTPYFALGL 420
EPEQSCADTPVFLAKPPIGFFTDYEIGPVYEMVIALQNTTTTSRYLRVLPPSTPYFALGL
Sbjct: 361 EPEQSCADTPVFLAKPPIGFFTDYEIGPVYEMVIALQNTTTTSRYLRVLPPSTPYFALGL 420
Query: 421 GMFPGKGGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLS 480
GMFPGKGGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLS
Sbjct: 421 GMFPGKGGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLS 480
Query: 481 PVLDCGYCLIGGVKMTRFICKNVGFSVGRFCIMPKTSWPPLSFKAIATVGFVEQPPFGIL 540
PVLDCGYCLIGGVKMTRFICKNVGFSVGRFCIMPKTSWPPLSFKAIATVGFVEQPPFGIL
Sbjct: 481 PVLDCGYCLIGGVKMTRFICKNVGFSVGRFCIMPKTSWPPLSFKAIATVGFVEQPPFGIL 540
Query: 541 PSVFELAPGHAILVEVLFSPKSLGKAEQTFIIMCDNCQIKELVTIGIGQLIALDLIYISG 600
PSVFELAPGHAILVEVLFSPKSLGKAEQTFIIMCDNCQIKELVTIGIGQLIALDLIYISG
Sbjct: 541 PSVFELAPGHAILVEVLFSPKSLGKAEQTFIIMCDNCQIKELVTIGIGQLIALDLIYISG 600
Query: 601 EKSQPDPGELTDLTAQHFIRFEPENLRSTARKQLIIRNATHVELAFYWQIMKPNLQPLMP 660
EKSQPDPGELTDLTAQHFIRFEPENLRSTARKQLIIRNATHVELAFYWQIMKPNLQPLMP
Sbjct: 601 EKSQPDPGELTDLTAQHFIRFEPENLRSTARKQLIIRNATHVELAFYWQIMKPNLQPLMP 660
Query: 661 GETFSMDSIKCYPDKETAFSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVLEEVP 720
GETFSMDSIKCYPDKETAFSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVLEEVP
Sbjct: 661 GETFSMDSIKCYPDKETAFSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVLEEVP 720
Query: 721 EPVSSEAESLGHSSYSVDDVIVLEIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKAFK 780
EPVSSEAESLGHSSYSVDDVIVLEIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKAFK
Sbjct: 721 EPVSSEAESLGHSSYSVDDVIVLEIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKAFK 780
Query: 781 MWNNSKSPIRYLWGKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIE 840
MWNNSKSPIRYLWGKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIE
Sbjct: 781 MWNNSKSPIRYLWGKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIE 840
Query: 841 DSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPV 900
DSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPV
Sbjct: 841 DSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPV 900
Query: 901 SLQERPEDVSPFDIEPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLPVY 960
SLQERPEDVSPFDIEPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLPVY
Sbjct: 901 SLQERPEDVSPFDIEPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLPVY 960
Query: 961 AEVQKPHVYLQSSQVEVRNLYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEFCMVTVS 1020
AEVQKPHVYLQSSQVEVRNLYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEFCMVTVS
Sbjct: 961 AEVQKPHVYLQSSQVEVRNLYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEFCMVTVS 1020
Query: 1021 PKHGLLGPSEECQLKLELTAHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITIS 1080
PKHGLLGPSEECQLKLELTAHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITIS
Sbjct: 1021 PKHGLLGPSEECQLKLELTAHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITIS 1080
Query: 1081 KESSDCSTEQWPGHPKELRLDFGSAVPLRTRVTRQLILTNRSPIRTRFSLKFEYFGSPQN 1140
KESSDCSTEQWPGHPKELRLDFGSAVPLRTRVTRQLILTNRSPIRTRFSLKFEYFGSPQN
Sbjct: 1081 KESSDCSTEQWPGHPKELRLDFGSAVPLRTRVTRQLILTNRSPIRTRFSLKFEYFGSPQN 1140
Query: 1141 SLSKKTSLPNMPPALLKTVRMQEHLAKREQLDFMESMLSHGKGAAFFPHFSQGMLGPYQQ 1200
SLSKKTSLPNMPPALLKTVRMQEHLAKREQLDFMESMLSHGKGAAFFPHFSQGMLGPYQQ
Sbjct: 1141 SLSKKTSLPNMPPALLKTVRMQEHLAKREQLDFMESMLSHGKGAAFFPHFSQGMLGPYQQ 1200
Query: 1201 LCIDITGCANMWGEYWDNLICTVGDLLPEVIPVHMAAVGCPISSLRTTSYTIDQAQKEPA 1260
LCIDITGCANMWGEYWDNLICTVGDLLPEVIPVHMAAVGCPISSLRTTSYTIDQAQKEPA
Sbjct: 1201 LCIDITGCANMWGEYWDNLICTVGDLLPEVIPVHMAAVGCPISSLRTTSYTIDQAQKEPA 1260
Query: 1261 MRFGTQVSGGDTVTRTLRLNNSSPCDIRLDWETYVPEDKEDRLVELLVFYGPPFPLRDQA 1320
MRFGTQVSGGDTVTRTLRLNNSSPCDIRLDWETYVPEDKEDRLVELLVFYGPPFPLRDQA
Sbjct: 1261 MRFGTQVSGGDTVTRTLRLNNSSPCDIRLDWETYVPEDKEDRLVELLVFYGPPFPLRDQA 1320
Query: 1321 GNELVCPDTPEGGCLLWSPGPSSSSEFSHETDSSVEGSSSASNRVAQKLISVILQAHEGV 1380
GNELVCPDTPEGGCLLWSPGPSSSSEFSHETDSSVEGSSSASNRVAQKLISVILQAHEGV
Sbjct: 1321 GNELVCPDTPEGGCLLWSPGPSSSSEFSHETDSSVEGSSSASNRVAQKLISVILQAHEGV 1380
Query: 1381 PSGHLYCISPKQVVVPAGGSSTIYISFTPMVLSPEILHKVECTGYALGFMSLDSKVEREI 1440
PSGHLYCISPKQVVVPAGGSSTIYISFTPMVLSPEILHKVECTGYALGFMSLDSKVEREI
Sbjct: 1381 PSGHLYCISPKQVVVPAGGSSTIYISFTPMVLSPEILHKVECTGYALGFMSLDSKVEREI 1440
Query: 1441 PGKRHRLQDFAVGPLKLDLHSYVRPAQLSVELDYGGSMEFQCQASDLIPEQPCSGVLSEL 1500
PGKRHRLQDFAVGPLKLDLHSYVRPAQLSVELDYGGSMEFQCQASDLIPEQPCSGVLSEL
Sbjct: 1441 PGKRHRLQDFAVGPLKLDLHSYVRPAQLSVELDYGGSMEFQCQASDLIPEQPCSGVLSEL 1500
Query: 1501 VTTHHLKLTNTTEIPHYFRLMVSRPFSVSQDGASQDHRAPGPGQKQECEEETASADKQLV 1560
VTTHHLKLTNTTEIPHYFRLMVSRPFSVSQDGASQDHRAPGPGQKQECEEETASADKQLV
Sbjct: 1501 VTTHHLKLTNTTEIPHYFRLMVSRPFSVSQDGASQDHRAPGPGQKQECEEETASADKQLV 1560
Query: 1561 LQAQENMLVNVSFSLSLELLSYQKLPADQTLPGVDIQQSASGEREMVFTQNLLLEYTNQT 1620
LQAQENMLVNVSFSLSLELLSYQKLPADQTLPGVDIQQSASGEREMVFTQNLLLEYTNQT
Sbjct: 1561 LQAQENMLVNVSFSLSLELLSYQKLPADQTLPGVDIQQSASGEREMVFTQNLLLEYTNQT 1620
Query: 1621 TQVVPLRAVVAVPELQLSTSWVDFGTCFVSQQRVREVYLMNLSGCRSYWTMLMG 1674
TQVVPLRAVVAVPELQLSTSWVDFGTCFVSQQRVREVYLMNLSGCRSYWTMLMG
Sbjct: 1621 TQVVPLRAVVAVPELQLSTSWVDFGTCFVSQQRVREVYLMNLSGCRSYWTMLMG 1674
Score = 32.3 bits (72), Expect = 4.2
Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 9/91 (9%)
Query: 1596 IQQSASGEREMVFT--------QNLLLEYTNQTTQVV-PLRAVVAVPELQLSTSWVDFGT 1646
I+ S G+ E+ FT Q+LL E + + VV + AV P L ++ S + FG
Sbjct: 811 IEPSEVGDFELNFTGGVPGPTSQDLLCEIEDSPSPVVLHIEAVFKGPALIINVSALQFGL 870
Query: 1647 CFVSQQRVREVYLMNLSGCRSYWTMLMGVVS 1677
+ Q+ + + N+S + W M VS
Sbjct: 871 LRLGQKATNSIQIRNVSQLPATWRMKESPVS 901
>gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]
Length = 5120
Score = 118 bits (296), Expect = 4e-26
Identities = 172/809 (21%), Positives = 307/809 (37%), Gaps = 111/809 (13%)
Query: 368 DTPVFLAKPPIGFFTDYEIGPVYEMVIALQNTTTTSRYLRVLPPSTPYFALGLGMFPGK- 426
D +F P F +Y VYE+ + L+N R ++V+ S+PYF + + P
Sbjct: 94 DQALFQPFPSEIIFQNYTPCEVYEVPLILRNNDKIPRLVKVVEESSPYFKV---ISPKDI 150
Query: 427 GGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLSPVLDCG 486
G VAPG+ + + F P+ D+ + T+ ++P++AR +L L+
Sbjct: 151 GHKVAPGVPSIFRILFTPEENKDYAHTLTCVTE-REKFIVPIKARGARAILDFPDKLNFS 209
Query: 487 YCLIGGVKMTRFICKNVGFSVGRFCIMPKTSWPPLSFKAIATVGFVEQPPFGILPSVFEL 546
C + + +N+G F I KT PF I P++ L
Sbjct: 210 TCPVKYSTQKILLVRNIGNKNAVFHI--KTC-----------------RPFSIEPAIGTL 250
Query: 547 APGHAILVEVLFSPKSLGKAEQTFIIMCDNCQ--IKELVTIGIGQLIALDLIYISGEKSQ 604
G ++ +EV F P+S+G I+ D + L I I LD ++ EK+
Sbjct: 251 NVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLDKNSLTIEKTY 310
Query: 605 PDPGELTDLTAQ-------HFI------RFEPENLRSTARKQLIIRNATHVELAFYWQIM 651
+T HF+ + E + + A LI + F I
Sbjct: 311 ISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDETDEFFEECIT 370
Query: 652 KPNLQPLMP--GETFSMDSIKCYPDKE----TAFSIMPRKGVLSPHTDHEFILSFSPHEL 705
P L+ + TF+ D + F++ P +G + P++ E + F+P E
Sbjct: 371 DPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAEITVYFNPLEA 430
Query: 706 RDFHSVL--QMVLEEVPEPVSSEAESLGHSSYSVDDVIVLEIEVKGSVEPFQVLLEPYAL 763
+ + + ++ E+ P+ + E +G + +++ + GS ++ +L
Sbjct: 431 KLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHCYEAIL----- 485
Query: 764 IIPGENYIGINVKKAFKMWNNSKSPIRYLWGKISDCHIIEVEPGTGVIEPSEVGDFELNF 823
Y ++ F M + + + C + P G+IEPS V +++F
Sbjct: 486 ------YNKGSIDALFNMTPPTSA--------LGACFVF--SPKEGIIEPSGVQAIQISF 529
Query: 824 TGGVPGPTSQDLLCEIEDSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQI 883
+ + G ++ L + SP PV L I GP NV AL FG + G T +
Sbjct: 530 SSTILGNFEEEFLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSL 589
Query: 884 RNVSQLPATWRMK--------------------ESPVSLQERPEDVSP--FDIEPSSGQL 921
N S +P T++++ + P +E + P F I P G +
Sbjct: 590 NNTSLIPMTYKLRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTI 649
Query: 922 HSLGECRVDITLEALHCQHLETVLELEVENGAWSYLP--VYAEVQKPHVYLQSSQVEVRN 979
G + +TL + Q E L ++VE L + A P ++L +++V+ +
Sbjct: 650 RPQGFAAIRVTLCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGH 709
Query: 980 LYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEFCMVTVSPKHGLLGPSEECQLKLELT 1039
+L P + T+ L N LP + + + + + G++ PS + L L
Sbjct: 710 CFLKYPYEKTLQLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLE 769
Query: 1040 AHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITISKESSDCSTEQWPGHPKELR 1099
E PLV + +G + + HP +
Sbjct: 770 TQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYV----------------HPNQ-- 811
Query: 1100 LDFGSAVPLRTRVTRQLILTNRSPIRTRF 1128
+DFG+ L+ +R L L N+S I F
Sbjct: 812 VDFGNIYVLKDS-SRILNLCNQSFIPAFF 839
Score = 45.8 bits (107), Expect = 4e-04
Identities = 34/146 (23%), Positives = 63/146 (43%), Gaps = 7/146 (4%)
Query: 804 VEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIEDSPSPVVLHIEAVFKGPALIINV 863
+EP T V++P+E + G ++C I D+P P + + P L +
Sbjct: 2878 LEPNTMVLKPNEKQILNVWAYPTSVGVFEDSIVCCINDNPEPAIFQLSCQGIRPELELEP 2937
Query: 864 SALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDVSPFDIEPSSGQLHS 923
L F L L ++ + + +RNV+ LP WR+ SL+ +D F + G +
Sbjct: 2938 RQLHFDRLLLHRQESRVVLLRNVTLLPVAWRI----TSLEHLGDD---FTVSLMQGTIPP 2990
Query: 924 LGECRVDITLEALHCQHLETVLELEV 949
E + + + +++ + LEV
Sbjct: 2991 EAEYGLHLYFQPTKPVNIKKAIRLEV 3016
Score = 39.3 bits (90), Expect = 0.034
Identities = 33/155 (21%), Positives = 69/155 (44%), Gaps = 9/155 (5%)
Query: 808 TGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIEDSPSP-VVLHIEAVFKGPALIINVSAL 866
+GVI PS L V G + I S P +V H+++ +GP + ++ + +
Sbjct: 753 SGVISPSSTIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYVHPNQV 812
Query: 867 QFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDVSPFDIEPSSGQLHSLGE 926
FG + + + ++ + + N S +PA ++ + S + IEP+ G + +
Sbjct: 813 DFGNIYVLKDSSRILNLCNQSFIPAFFQAHMA--------HKKSLWTIEPNEGMVPPETD 864
Query: 927 CRVDITLEALHCQHLETVLELEVENGAWSYLPVYA 961
++ +T + + L++EN + +PV A
Sbjct: 865 VQLALTANLNDTLTFKDCVILDIENSSTYRIPVQA 899
Score = 38.5 bits (88), Expect = 0.059
Identities = 91/407 (22%), Positives = 157/407 (38%), Gaps = 52/407 (12%)
Query: 620 RFEPENLRSTARKQLI--IRNATHVELAFYW-QIMKPNLQPLMPGETFSMDSIKCYPDKE 676
R E + LR T +I +R H E Y Q + + L E M SI E
Sbjct: 1271 RPEEKELRKTKASSVISDVRCPFHGEERIYSSQSQVEDQESLQTCEQNEMLSIGI----E 1326
Query: 677 TAFSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQ-MVLEEVPEPVSSEAESLGHSS- 734
F I+P GVL PH+ H+ +F H + + Q L EV E + E G +S
Sbjct: 1327 EVFDILPLFGVLQPHSSHQISFTFYGHA----NIIAQAKALCEVEEGPTYEITLKGEASL 1382
Query: 735 --YSVDDVIVLEIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKAFKMWNNSKSPIRYL 792
YS D ++ ++ F + E + + +G K + ++ SP L
Sbjct: 1383 VNYSFDTK-----DIHYGLQLFDHVTE-REITLTNMGKVGFEFK---VLTDHQSSPDNLL 1433
Query: 793 WGKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIED-SPSPVVLHIE 851
G + + P +G I + ++ + GVP + +I P + L E
Sbjct: 1434 PG------VPLILPVSGFISSHQEQVLKVYYLPGVPEVFKRSFQIQIAHLDPENITLSGE 1487
Query: 852 AVFKGPALII--NVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDV 909
+F L + N++A + + L Q N+ + N ++ + + +E PED
Sbjct: 1488 GIFPQICLDLPRNLTANEKYEMFLNQARKNTDKEYNKCEM-----LDHFDIITEEVPED- 1541
Query: 910 SPFDIEPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLP--VYAEVQKPH 967
EP+ H E + +++ +H +T +++ +S+ A++Q P
Sbjct: 1542 -----EPAEVSAHLQMEVE-RLIVQSYVLEHQKTTTPDPMDDPCFSHRSRRKLAKIQLPE 1595
Query: 968 VYLQSSQVEVRNLYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEF 1014
L + LG I +IN + P FH K + H+ F
Sbjct: 1596 YILDFGYI-----ILGEVRTHIIKIINTSHFPVSFHADKRVLHETGF 1637
Score = 36.6 bits (83), Expect = 0.22
Identities = 49/227 (21%), Positives = 88/227 (38%), Gaps = 26/227 (11%)
Query: 679 FSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVL------EEVPEPVSSEAESLGH 732
FS+ P G++ +F + FSP ++ DF S L + E+ P V+ +L
Sbjct: 3889 FSVEPSSGIVPVGKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPVLVAKGRSTLPI 3948
Query: 733 SSYSVDDVIVL-----EIEVKGS----VEPFQVLLEPYALIIPGENYIGINVKKAFKMWN 783
+ + D + E++GS ++P ++E + I G+N + F + N
Sbjct: 3949 CHFDLKDSDYISGHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNL------RTFTILN 4002
Query: 784 NSKSPIRYLW-----GKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCE 838
+ S + W + + G I P + + FT G T
Sbjct: 4003 PTNSTYSFCWISEEIESLQNPAAFTCLTEKGFIHPEKKAEIVFQFTPFHLGITESSWTFL 4062
Query: 839 IEDSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQIRN 885
I + V + P + +N S L F L +G++A ++QI N
Sbjct: 4063 IPEHNITVPFLLVGKTTEPLISLNKSHLNFSSLLIGREARETVQIIN 4109
Score = 35.8 bits (81), Expect = 0.38
Identities = 86/480 (17%), Positives = 185/480 (38%), Gaps = 57/480 (11%)
Query: 681 IMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVLEEVPEPVSSEAESLGHSSYSVDDV 740
+ P +G + P + + F+P + D + L +E+ PV+ ++ G++
Sbjct: 4135 VCPMEGWIPPLSRFPIDIFFTPKQEGDVNFNLICNVEKKVHPVTLNVKAEGYT------- 4187
Query: 741 IVLEIEVK-----GSVEPFQVLLEPYALIIPGENYIGIN--VKKAFKMWNNSKSPIRY-- 791
+ +E+K GS+ LL P I + +N V+ F N K +
Sbjct: 4188 --MNVEIKCKDRTGSI----TLLTPNQTNIINFYEVELNECVQCEFNFINTGKFTFSFQA 4241
Query: 792 -LWGKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGP-TSQDLLCEIEDSPSPVVLH 849
L G + +E P ++ + L+F T +L+ +I P+ + +
Sbjct: 4242 QLCGSKTLLQYLEFSPIDSTVDVGQSVHATLSFQPLKKCVLTDLELIIKISHGPT-FMCN 4300
Query: 850 IEAVFKGPALIINVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDV 909
I PA+ + ++ FG + Q + Q +E+P+S+ +
Sbjct: 4301 ISGCAVSPAIHFSFTSYNFGTCFIYQAGMPPYK-----QTLVITNKEETPMSIDCLYTNT 4355
Query: 910 SPFDIEPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLPVYAEVQKPHVY 969
+ ++ + + IT + + ++ E+ + + + + K +
Sbjct: 4356 THLEVNSRVDVVKPGNTLEIPITFYPRESINYQELIPFEINGLSQQTVEIKGKGTKMKIL 4415
Query: 970 LQSSQVEVRNLYLGVP---TKTTITLINGTLLPTQFHWGKL--LGHQAEFCMVTVSPKHG 1024
+ + L +P K T++++N +L F+ L + E ++T++P H
Sbjct: 4416 VLDPANRIVKLGAVLPGQVVKRTVSIMNNSLAQLTFNQSILFTIPELQEPKVLTLAPFHN 4475
Query: 1025 L-LGPSEECQLKLELTAHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITISKES 1083
+ L P E C+L++ + + G+ +PL L +SG Q L++++
Sbjct: 4476 ITLKPKEVCKLEVIFAPKKRVPPFSEEVFMECMGLLRPLFL-LSGCCQALEISLD----- 4529
Query: 1084 SDCSTEQWPGHPKELRLDFGSAVPLRTRVTRQLILTNRSPIRTRFSLKFEYFGSPQNSLS 1143
+ + FG V +T+ TR++++ N + RF + F P S+S
Sbjct: 4530 -------------QEHIPFGPVV-YQTQATRRILMMNTGDVGARFKWDIKKF-EPHFSIS 4574
Score = 34.7 bits (78), Expect = 0.85
Identities = 75/343 (21%), Positives = 121/343 (35%), Gaps = 73/343 (21%)
Query: 536 PFGILPSVFELAPGHAILVEVLFSPKSLGKAEQTFIIMCDNCQ---------IKELVTIG 586
PF + PS + G +V FSP +G E N K T+
Sbjct: 3888 PFSVEPSSGIVPVGKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPVLVAKGRSTLP 3947
Query: 587 IGQLIALDLIYISGEKSQPD-----PGELTDLTAQHFIRFEPENLRSTARKQLIIRNATH 641
I D YISG + P+ G L T I F + + I N T+
Sbjct: 3948 ICHFDLKDSDYISGHQRNPELRGSSGGALDPNT--RVIEFTTVGIGGKNLRTFTILNPTN 4005
Query: 642 VELAFYWQIMKPNLQPLMPGETFSMDSIKCYPDKETAFSIMPRKGVLSPHTDHEFILSFS 701
+F W + ++ L AF+ + KG + P E + F+
Sbjct: 4006 STYSFCW--ISEEIESLQ---------------NPAAFTCLTEKGFIHPEKKAEIVFQFT 4048
Query: 702 PHELRDFHSVLQMVLEE----VP--------EPVSSEAESLGHSSYSVDDVIVLEIEVKG 749
P L S ++ E VP EP+ S +S H ++S +++ E +
Sbjct: 4049 PFHLGITESSWTFLIPEHNITVPFLLVGKTTEPLISLNKS--HLNFS---SLLIGREARE 4103
Query: 750 SVEPFQVLLEPYALIIPGENYIGINVKKAFKMWNNSKSPIRYLWGKISDCHIIEVEPGTG 809
+V+ I + G + F +NS RY G + + +E G
Sbjct: 4104 TVQ------------IINKEEQGFD----FSFQDNS----RYSEGFSNSLLVCPME---G 4140
Query: 810 VIEPSEVGDFELNFTGGVPGPTSQDLLCEIEDSPSPVVLHIEA 852
I P ++ FT G + +L+C +E PV L+++A
Sbjct: 4141 WIPPLSRFPIDIFFTPKQEGDVNFNLICNVEKKVHPVTLNVKA 4183
Score = 32.0 bits (71), Expect = 5.5
Identities = 70/355 (19%), Positives = 123/355 (34%), Gaps = 90/355 (25%)
Query: 376 PPIGF-FTDYEIG---------PVYEMVIALQNTTTTSRYLRVLPPSTPYFALGLGMFPG 425
P I F FT Y G P Y+ + + N T + L +T + +
Sbjct: 4308 PAIHFSFTSYNFGTCFIYQAGMPPYKQTLVITNKEETPMSIDCLYTNTTHLEVN-----S 4362
Query: 426 KGGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPP-PVLTLSP--- 481
+ +V PG T + + F+P ++ + I E + ++ + +L L P
Sbjct: 4363 RVDVVKPGNTLEIPITFYPRESINYQELIPFEINGLSQQTVEIKGKGTKMKILVLDPANR 4422
Query: 482 VLDCGYCLIGGVKMTRFICKNVGFSVGRFCIMPKTSWPPLSFKA--IATVGFVEQPPFGI 539
++ G L G V V R + S L+F + T+ +++P
Sbjct: 4423 IVKLGAVLPGQV-------------VKRTVSIMNNSLAQLTFNQSILFTIPELQEP---- 4465
Query: 540 LPSVFELAPGHAILV--------EVLFSPKS-LGKAEQTFIIMCDNCQIKELVTIGIGQL 590
V LAP H I + EV+F+PK + + + C + G Q
Sbjct: 4466 --KVLTLAPFHNITLKPKEVCKLEVIFAPKKRVPPFSEEVFMECMGLLRPLFLLSGCCQA 4523
Query: 591 IALDLIYISGEKSQPDPGELTDLTAQHFIRFEPENLRSTARKQLIIRNATHVELAFYWQI 650
+ + L Q I F P ++ A +++++ N V F W I
Sbjct: 4524 LEISL-------------------DQEHIPFGPVVYQTQATRRILMMNTGDVGARFKWDI 4564
Query: 651 MKPNLQPLMPGETFSMDSIKCYPDKETAFSIMPRKGVLSPHTDHEFILSFSPHEL 705
K E FSI P +G ++ + F +++ P E+
Sbjct: 4565 KK----------------------FEPHFSISPEEGYITSGMEVSFEVTYHPTEV 4597
>gi|46361983 hydrocephalus inducing isoform b [Homo sapiens]
Length = 1017
Score = 118 bits (296), Expect = 4e-26
Identities = 172/809 (21%), Positives = 307/809 (37%), Gaps = 111/809 (13%)
Query: 368 DTPVFLAKPPIGFFTDYEIGPVYEMVIALQNTTTTSRYLRVLPPSTPYFALGLGMFPGK- 426
D +F P F +Y VYE+ + L+N R ++V+ S+PYF + + P
Sbjct: 94 DQALFQPFPSEIIFQNYTPCEVYEVPLILRNNDKIPRLVKVVEESSPYFKV---ISPKDI 150
Query: 427 GGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLSPVLDCG 486
G VAPG+ + + F P+ D+ + T+ ++P++AR +L L+
Sbjct: 151 GHKVAPGVPSIFRILFTPEENKDYAHTLTCVTE-REKFIVPIKARGARAILDFPDKLNFS 209
Query: 487 YCLIGGVKMTRFICKNVGFSVGRFCIMPKTSWPPLSFKAIATVGFVEQPPFGILPSVFEL 546
C + + +N+G F I KT PF I P++ L
Sbjct: 210 TCPVKYSTQKILLVRNIGNKNAVFHI--KTC-----------------RPFSIEPAIGTL 250
Query: 547 APGHAILVEVLFSPKSLGKAEQTFIIMCDNCQ--IKELVTIGIGQLIALDLIYISGEKSQ 604
G ++ +EV F P+S+G I+ D + L I I LD ++ EK+
Sbjct: 251 NVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLDKNSLTIEKTY 310
Query: 605 PDPGELTDLTAQ-------HFI------RFEPENLRSTARKQLIIRNATHVELAFYWQIM 651
+T HF+ + E + + A LI + F I
Sbjct: 311 ISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDETDEFFEECIT 370
Query: 652 KPNLQPLMP--GETFSMDSIKCYPDKE----TAFSIMPRKGVLSPHTDHEFILSFSPHEL 705
P L+ + TF+ D + F++ P +G + P++ E + F+P E
Sbjct: 371 DPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAEITVYFNPLEA 430
Query: 706 RDFHSVL--QMVLEEVPEPVSSEAESLGHSSYSVDDVIVLEIEVKGSVEPFQVLLEPYAL 763
+ + + ++ E+ P+ + E +G + +++ + GS ++ +L
Sbjct: 431 KLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHCYEAIL----- 485
Query: 764 IIPGENYIGINVKKAFKMWNNSKSPIRYLWGKISDCHIIEVEPGTGVIEPSEVGDFELNF 823
Y ++ F M + + + C + P G+IEPS V +++F
Sbjct: 486 ------YNKGSIDALFNMTPPTSA--------LGACFVF--SPKEGIIEPSGVQAIQISF 529
Query: 824 TGGVPGPTSQDLLCEIEDSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQI 883
+ + G ++ L + SP PV L I GP NV AL FG + G T +
Sbjct: 530 SSTILGNFEEEFLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSL 589
Query: 884 RNVSQLPATWRMK--------------------ESPVSLQERPEDVSP--FDIEPSSGQL 921
N S +P T++++ + P +E + P F I P G +
Sbjct: 590 NNTSLIPMTYKLRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTI 649
Query: 922 HSLGECRVDITLEALHCQHLETVLELEVENGAWSYLP--VYAEVQKPHVYLQSSQVEVRN 979
G + +TL + Q E L ++VE L + A P ++L +++V+ +
Sbjct: 650 RPQGFAAIRVTLCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGH 709
Query: 980 LYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEFCMVTVSPKHGLLGPSEECQLKLELT 1039
+L P + T+ L N LP + + + + + G++ PS + L L
Sbjct: 710 CFLKYPYEKTLQLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLE 769
Query: 1040 AHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITISKESSDCSTEQWPGHPKELR 1099
E PLV + +G + + HP +
Sbjct: 770 TQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYV----------------HPNQ-- 811
Query: 1100 LDFGSAVPLRTRVTRQLILTNRSPIRTRF 1128
+DFG+ L+ +R L L N+S I F
Sbjct: 812 VDFGNIYVLKDS-SRILNLCNQSFIPAFF 839
Score = 39.3 bits (90), Expect = 0.034
Identities = 33/155 (21%), Positives = 69/155 (44%), Gaps = 9/155 (5%)
Query: 808 TGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIEDSPSP-VVLHIEAVFKGPALIINVSAL 866
+GVI PS L V G + I S P +V H+++ +GP + ++ + +
Sbjct: 753 SGVISPSSTIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYVHPNQV 812
Query: 867 QFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDVSPFDIEPSSGQLHSLGE 926
FG + + + ++ + + N S +PA ++ + S + IEP+ G + +
Sbjct: 813 DFGNIYVLKDSSRILNLCNQSFIPAFFQAHMA--------HKKSLWTIEPNEGMVPPETD 864
Query: 927 CRVDITLEALHCQHLETVLELEVENGAWSYLPVYA 961
++ +T + + L++EN + +PV A
Sbjct: 865 VQLALTANLNDTLTFKDCVILDIENSSTYRIPVQA 899
>gi|122937416 hypothetical protein LOC85452 [Homo sapiens]
Length = 762
Score = 43.9 bits (102), Expect = 0.001
Identities = 38/144 (26%), Positives = 64/144 (44%), Gaps = 3/144 (2%)
Query: 372 FLAKPPIGFFTDYEIGPVYEMVIALQNTTTTSRYLRVLPPSTPYFALGLGMFPGKGGMVA 431
F +KP + F D++IG VY+ I L NTT T Y +++ + + + G ++
Sbjct: 515 FNSKPELLHFQDFDIGKVYKKKITLVNTTYTINYCKLVGVE-EHLRDFIHVDFDPPGPLS 573
Query: 432 PGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTL-SPVLDCGYCLI 490
GM+C+ +V F P D + I Q+ +PL+ L+L ++D G ++
Sbjct: 574 AGMSCEVLVTFKPMINKDLEGNISFLAQTGE-FSVPLKCSTKKCSLSLDKELIDFGSYVV 632
Query: 491 GGVKMTRFICKNVGFSVGRFCIMP 514
G NVG F +P
Sbjct: 633 GETTSRTITLTNVGGLGTTFKFLP 656
>gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo
sapiens]
Length = 1925
Score = 38.5 bits (88), Expect = 0.059
Identities = 19/74 (25%), Positives = 41/74 (55%), Gaps = 3/74 (4%)
Query: 744 EIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKAFKMWNNSKSPIRYLWGKISDCH--I 801
E+ + EP Q+ L+ + + ++G + F N S+ P+++ W ++S+ H +
Sbjct: 866 EVSMYSREEPLQLKLDTHKSLYFKPTWVGCSSTSPFTFRNPSRLPLQFEW-RVSEQHRKL 924
Query: 802 IEVEPGTGVIEPSE 815
+ V+P G+I+P+E
Sbjct: 925 LAVQPSRGLIQPNE 938
Score = 32.3 bits (72), Expect = 4.2
Identities = 41/178 (23%), Positives = 71/178 (39%), Gaps = 25/178 (14%)
Query: 384 YEIGPVYEMVIALQNTTTTSRYLRVLPPSTPYFALGLGMFPGKGGMVAPGMTCQYIVQFF 443
+E+G + L+N + + ++ PP T +F + P + ++PG+T + F
Sbjct: 156 WELGKETTRNLVLKNRSLKLQKMKYRPPKTKFF---FTVIP-QPIFLSPGITLTLPIVFR 211
Query: 444 PDCLGDFDDFILVETQSAHTLLIPLQARRP-PPVLTLSPVLDCGYCLIGGVKMTRFICKN 502
P ++ D + E ++ + L+A P ++ P L C +G F N
Sbjct: 212 PLEAKEYMDQLWFE-KAEGMFCVGLRATLPCHRLICRPPSLQLPMCAVGDTTEAFFCLDN 270
Query: 503 VGFSVGRFCIMPKTSWPPLSFKAIATVGFVEQPPFGILPSVFELAPGHAILVEVLFSP 560
VG F +W S PF +LP+ L PG A ++V F P
Sbjct: 271 VGDLPTFF------TWEFSS-------------PFQMLPATGLLEPGQASQIKVTFQP 309
Score = 31.2 bits (69), Expect = 9.4
Identities = 59/289 (20%), Positives = 107/289 (37%), Gaps = 39/289 (13%)
Query: 664 FSMDSIKCYP-----DKETAFSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVLEE 718
F +D++ P + + F ++P G+L P + ++F P L V+ E
Sbjct: 266 FCLDNVGDLPTFFTWEFSSPFQMLPATGLLEPGQASQIKVTFQP---------LTAVIYE 316
Query: 719 VPEPVSSEAESLGHSSYSVDDVIV---LEIEVKGSVEPFQVLLEPYALIIPGENYIGINV 775
V A S SS + V L + +K Q L+ G +G
Sbjct: 317 VQATCWYGAGSRQRSSIQLQAVAKCAQLLVSIKHKCPEDQDAEGFQKLLYFGSVAVGCTS 376
Query: 776 KKAFKMWN----NSKSPIRYLWGKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPT 831
++ ++ N N+ I ++++ G++ P E + F
Sbjct: 377 ERQIRLHNPSAVNAPFRIEISPDELAEDQAFSCPTAHGIVLPGEKKCVSVFFHPKTLDTR 436
Query: 832 SQDLLCEIEDS--PSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQIRNVSQL 889
+ D C I S S +L + +GPA+ + + F + LG+++ + I N S
Sbjct: 437 TVDY-CSIMPSGCASKTLLKVVGFCRGPAVSLQHYCVNFSWVNLGERSEQPLWIENQSDC 495
Query: 890 PATWRMKESPVSLQERPEDVSPFDIEPSSGQLHSLGECRVDITLEALHC 938
A ++ + S F I P+ G L +G+ R+ LHC
Sbjct: 496 TAHFQFAIDCLE--------SVFTIRPAFGTL--VGKARM-----TLHC 529
Score = 31.2 bits (69), Expect = 9.4
Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 5/69 (7%)
Query: 981 YLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEFCMVTVSPKHGLLGPSEECQLKLELTA 1040
++G + + T N + LP QF W H+ ++ V P GL+ P+E +L L T
Sbjct: 892 WVGCSSTSPFTFRNPSRLPLQFEWRVSEQHRK---LLAVQPSRGLIQPNE--RLTLTWTF 946
Query: 1041 HTQEELTHL 1049
EE +L
Sbjct: 947 SPLEETKYL 955
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 38.1 bits (87), Expect = 0.077
Identities = 43/175 (24%), Positives = 77/175 (44%), Gaps = 19/175 (10%)
Query: 126 ERHEEFVDQLQQIRELYKQRLDEFEMLERHITQAQARAIAENERVMSQAG-VQDLESLVR 184
ER ++ Q +QIREL K R + +LE + + + + ++ + SQ G VQDL+
Sbjct: 1498 EREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKK----DQMIESQRGQVQDLKK--- 1550
Query: 185 LPPVKSVSRWCIDSELLRKHHLISPEDYYTDTVPFHSAPKGISLPGCSKLTFSCEKRSVQ 244
+ V+ C+ EL HH + + + + ++L + LT E+RS +
Sbjct: 1551 ----QLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVAL---THLTLDLEERSQE 1603
Query: 245 KKELNKKLED--SCRKKLAEFEDELDHTVDSLTWNL--TPKAKERTREPLKKASQ 295
+ + ++ D S LA E D V S + + KE + L++ Q
Sbjct: 1604 LQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQ 1658
>gi|169217799 PREDICTED: hypothetical protein [Homo sapiens]
Length = 149
Score = 37.0 bits (84), Expect = 0.17
Identities = 24/104 (23%), Positives = 47/104 (45%), Gaps = 13/104 (12%)
Query: 4 RSSKTRRSLASRTNEC----QGTMWAPTSPPAGSSSPSQPTWKSSLYSSLAYSEAFHYSF 59
R+S+ S A+R+ C QG+ W+ P +S P QP++ + + + +
Sbjct: 3 RTSRWAGSAANRSQWCLAIQQGSTWSSQEPWPSTSWPEQPSYSNKRVTKMGMLSTSKSNA 62
Query: 60 AARPRRLTQLALAQRPEPQLL---------RLRPSSLRTQDISH 94
+ + ++ + + EP+ L RLRP+ L +Q+ H
Sbjct: 63 SQAQWLMPEIPMPETLEPEQLHLEQELGKMRLRPAGLHSQEFRH 106
>gi|239752508 PREDICTED: hypothetical protein XP_002347011 [Homo
sapiens]
Length = 149
Score = 37.0 bits (84), Expect = 0.17
Identities = 24/104 (23%), Positives = 47/104 (45%), Gaps = 13/104 (12%)
Query: 4 RSSKTRRSLASRTNEC----QGTMWAPTSPPAGSSSPSQPTWKSSLYSSLAYSEAFHYSF 59
R+S+ S A+R+ C QG+ W+ P +S P QP++ + + + +
Sbjct: 3 RTSRWAGSAANRSQWCLAIQQGSTWSSQEPWPSTSWPEQPSYSNKRVTKMGMLSTSKSNA 62
Query: 60 AARPRRLTQLALAQRPEPQLL---------RLRPSSLRTQDISH 94
+ + ++ + + EP+ L RLRP+ L +Q+ H
Sbjct: 63 SQAQWLMPEIPMPETLEPEQLHLEQELGKMRLRPAGLHSQEFRH 106
>gi|239743770 PREDICTED: hypothetical protein XP_002342956 [Homo
sapiens]
Length = 149
Score = 37.0 bits (84), Expect = 0.17
Identities = 24/104 (23%), Positives = 47/104 (45%), Gaps = 13/104 (12%)
Query: 4 RSSKTRRSLASRTNEC----QGTMWAPTSPPAGSSSPSQPTWKSSLYSSLAYSEAFHYSF 59
R+S+ S A+R+ C QG+ W+ P +S P QP++ + + + +
Sbjct: 3 RTSRWAGSAANRSQWCLAIQQGSTWSSQEPWPSTSWPEQPSYSNKRVTKMGMLSTSKSNA 62
Query: 60 AARPRRLTQLALAQRPEPQLL---------RLRPSSLRTQDISH 94
+ + ++ + + EP+ L RLRP+ L +Q+ H
Sbjct: 63 SQAQWLMPEIPMPETLEPEQLHLEQELGKMRLRPAGLHSQEFRH 106
>gi|58331242 formin homology 2 domain containing 3 [Homo sapiens]
Length = 1439
Score = 35.4 bits (80), Expect = 0.50
Identities = 45/182 (24%), Positives = 73/182 (40%), Gaps = 17/182 (9%)
Query: 2 ETRSSKTRRSLASRTNECQGTMWAPTSP---PAGSSSPSQPTWKSSLYSSLAYSEAFHYS 58
E R RRS + T+ APTSP A S P+Q YS+ + ++H S
Sbjct: 353 EHRGLDRRRSRRHSVQSIKSTLSAPTSPCSQSAPSFKPNQVRDLREKYSNFG-NNSYHSS 411
Query: 59 FAARPRRLTQLALAQRPEPQLLRLRPSSLRTQDISHLLTGVFRNLYSAEVIGDEVSASLI 118
+ + + PQ RL SS S LLT FR + E
Sbjct: 412 RPSSGSSVPTTPTSSVSPPQEARLERSS-----PSGLLTSSFRQHQESLAAERERRRQER 466
Query: 119 KARGSENERHE------EFVDQLQQIRELYKQRLDEFEML--ERHITQAQARAIAENERV 170
+ R ER E +++D+ ++ R+ ++R E L E H + ++R+++
Sbjct: 467 EERLQRIEREERNKFSRDYLDKREEQRQAREERYKYLEQLAAEEHEKELRSRSVSRGRAD 526
Query: 171 MS 172
+S
Sbjct: 527 LS 528
>gi|33946313 ninein isoform 4 [Homo sapiens]
Length = 2096
Score = 35.4 bits (80), Expect = 0.50
Identities = 66/248 (26%), Positives = 100/248 (40%), Gaps = 43/248 (17%)
Query: 114 SASLIKARGSENERHEEFVDQLQQIRELYKQRLDE-----FEM-LERHITQAQARAIAEN 167
+A L +A RHEE QLQ E K L E EM L+ +TQAQA E
Sbjct: 689 AAVLKEAHHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFERER 748
Query: 168 ERVMSQAGVQD-------------LESLVRLPPVKSVSRWCIDSELLRKHH---LISPED 211
E + S A ++ E L L ++ + + ELL KH E
Sbjct: 749 EGLQSSAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKELLEKHQRELQEGREK 808
Query: 212 YYTDTVPFHSAPKGISLPGCSKLTFSCEK--RSVQ---KKELNKKLEDSCRKKLAEFEDE 266
T+ S + C K+T CE +S++ ++EL K L++ R++ +++E E
Sbjct: 809 METECNRRTSQIEAQFQSDCQKVTERCESALQSLEGRYRQEL-KDLQEQQREEKSQWEFE 867
Query: 267 LDHTVDSLTWNLTPKAKERTREPLKK-------ASQPR---NKNWMNHLRVPQRELDRLL 316
D +A+E +E LK+ +Q R K + HL E +LL
Sbjct: 868 KDELTQECA-----EAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLL 922
Query: 317 LARMESRN 324
+ RN
Sbjct: 923 QDLEDLRN 930
>gi|33946321 ninein isoform 5 [Homo sapiens]
Length = 2090
Score = 35.4 bits (80), Expect = 0.50
Identities = 66/248 (26%), Positives = 100/248 (40%), Gaps = 43/248 (17%)
Query: 114 SASLIKARGSENERHEEFVDQLQQIRELYKQRLDE-----FEM-LERHITQAQARAIAEN 167
+A L +A RHEE QLQ E K L E EM L+ +TQAQA E
Sbjct: 683 AAVLKEAHHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFERER 742
Query: 168 ERVMSQAGVQD-------------LESLVRLPPVKSVSRWCIDSELLRKHH---LISPED 211
E + S A ++ E L L ++ + + ELL KH E
Sbjct: 743 EGLQSSAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKELLEKHQRELQEGREK 802
Query: 212 YYTDTVPFHSAPKGISLPGCSKLTFSCEK--RSVQ---KKELNKKLEDSCRKKLAEFEDE 266
T+ S + C K+T CE +S++ ++EL K L++ R++ +++E E
Sbjct: 803 METECNRRTSQIEAQFQSDCQKVTERCESALQSLEGRYRQEL-KDLQEQQREEKSQWEFE 861
Query: 267 LDHTVDSLTWNLTPKAKERTREPLKK-------ASQPR---NKNWMNHLRVPQRELDRLL 316
D +A+E +E LK+ +Q R K + HL E +LL
Sbjct: 862 KDELTQECA-----EAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLL 916
Query: 317 LARMESRN 324
+ RN
Sbjct: 917 QDLEDLRN 924
>gi|148536871 ninein isoform 1 [Homo sapiens]
Length = 2046
Score = 35.4 bits (80), Expect = 0.50
Identities = 66/248 (26%), Positives = 100/248 (40%), Gaps = 43/248 (17%)
Query: 114 SASLIKARGSENERHEEFVDQLQQIRELYKQRLDE-----FEM-LERHITQAQARAIAEN 167
+A L +A RHEE QLQ E K L E EM L+ +TQAQA E
Sbjct: 683 AAVLKEAHHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFERER 742
Query: 168 ERVMSQAGVQD-------------LESLVRLPPVKSVSRWCIDSELLRKHH---LISPED 211
E + S A ++ E L L ++ + + ELL KH E
Sbjct: 743 EGLQSSAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKELLEKHQRELQEGREK 802
Query: 212 YYTDTVPFHSAPKGISLPGCSKLTFSCEK--RSVQ---KKELNKKLEDSCRKKLAEFEDE 266
T+ S + C K+T CE +S++ ++EL K L++ R++ +++E E
Sbjct: 803 METECNRRTSQIEAQFQSDCQKVTERCESALQSLEGRYRQEL-KDLQEQQREEKSQWEFE 861
Query: 267 LDHTVDSLTWNLTPKAKERTREPLKK-------ASQPR---NKNWMNHLRVPQRELDRLL 316
D +A+E +E LK+ +Q R K + HL E +LL
Sbjct: 862 KDELTQECA-----EAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLL 916
Query: 317 LARMESRN 324
+ RN
Sbjct: 917 QDLEDLRN 924
>gi|148536869 ninein isoform 2 [Homo sapiens]
Length = 2133
Score = 35.4 bits (80), Expect = 0.50
Identities = 66/248 (26%), Positives = 100/248 (40%), Gaps = 43/248 (17%)
Query: 114 SASLIKARGSENERHEEFVDQLQQIRELYKQRLDE-----FEM-LERHITQAQARAIAEN 167
+A L +A RHEE QLQ E K L E EM L+ +TQAQA E
Sbjct: 683 AAVLKEAHHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFERER 742
Query: 168 ERVMSQAGVQD-------------LESLVRLPPVKSVSRWCIDSELLRKHH---LISPED 211
E + S A ++ E L L ++ + + ELL KH E
Sbjct: 743 EGLQSSAWTEEKVRGLTQELEQFHQEQLTSLVEKHTLEKEELRKELLEKHQRELQEGREK 802
Query: 212 YYTDTVPFHSAPKGISLPGCSKLTFSCEK--RSVQ---KKELNKKLEDSCRKKLAEFEDE 266
T+ S + C K+T CE +S++ ++EL K L++ R++ +++E E
Sbjct: 803 METECNRRTSQIEAQFQSDCQKVTERCESALQSLEGRYRQEL-KDLQEQQREEKSQWEFE 861
Query: 267 LDHTVDSLTWNLTPKAKERTREPLKK-------ASQPR---NKNWMNHLRVPQRELDRLL 316
D +A+E +E LK+ +Q R K + HL E +LL
Sbjct: 862 KDELTQECA-----EAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLL 916
Query: 317 LARMESRN 324
+ RN
Sbjct: 917 QDLEDLRN 924
>gi|90963001 hypothetical protein LOC170063 [Homo sapiens]
Length = 976
Score = 34.3 bits (77), Expect = 1.1
Identities = 29/106 (27%), Positives = 46/106 (43%), Gaps = 4/106 (3%)
Query: 381 FTDYEIGPVYEMVIALQNTTTTSRYLRVLPPSTPYFALGLGMFPGKGGMVAPGMTCQYIV 440
F D G VY + I + N ++ +R P P F L M +A G+ +V
Sbjct: 49 FLDTMAGRVYRLPITVHNICRWNQKIRFKEPVKPQFKL---MLTSLDKELASGLQMTAMV 105
Query: 441 QFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLSPVLDCG 486
++ PD D D +L+ ++ T IPL P L + V++ G
Sbjct: 106 EYHPDKDEDTFDRLLISIEN-KTTEIPLIGLIPSCQLEIESVVNFG 150
>gi|4557719 DNA ligase I [Homo sapiens]
Length = 919
Score = 33.1 bits (74), Expect = 2.5
Identities = 58/250 (23%), Positives = 95/250 (38%), Gaps = 19/250 (7%)
Query: 119 KARGSENERHEEFVDQLQQIRELYKQRLDEFEMLERHITQAQARAIAENERVMSQAGVQD 178
K G + +E + ++ K L E+ + R + RV+ G ++
Sbjct: 12 KKEGKAKKPEKEASNSSRETEPPPKAALKEWNGVVSESDSPVKRPGRKAARVLGSEGEEE 71
Query: 179 LESLVRLPPVKSVSRWCIDSELLRKHHLISPEDY--YTDTVPFHSAPKGISLPGCSKLTF 236
E+L P K S++ SPE+ +DT P S+P GI P
Sbjct: 72 DEAL---SPAKGQKPALDCSQVSPPRPATSPENNASLSDTSPMDSSPSGI--PKRRTARK 126
Query: 237 SCEKRSVQKKELNKKLEDSCRKKLAEFEDELDHTV-DSLTWNLTPKAKERTREPLKKASQ 295
KR++Q+ L ++ ED R+ + E+E + T +SLT A E+ E + +
Sbjct: 127 QLPKRTIQEV-LEEQSEDEDREAKRKKEEEEEETPKESLTE--AEVATEKEGEDGDQPTT 183
Query: 296 PRNKNWMNHLRVPQRELDRLLLA---RMESRNHFLKNPRFFPPNTRYGGKSLVFPPKKPA 352
P + P + +A ++ K PR P S F P+KPA
Sbjct: 184 PPKPLKTSKAETPTESVSEPEVATKQELQEEEEQTKPPRRAPKTL-----SSFFTPRKPA 238
Query: 353 PIGEFQSTEP 362
E + EP
Sbjct: 239 VKKEVKEEEP 248
>gi|239756270 PREDICTED: StAR-related lipid transfer (START) domain
containing 9 [Homo sapiens]
Length = 4614
Score = 32.7 bits (73), Expect = 3.2
Identities = 20/62 (32%), Positives = 28/62 (45%)
Query: 1533 ASQDHRAPGPGQKQECEEETASADKQLVLQAQENMLVNVSFSLSLELLSYQKLPADQTLP 1592
+ ++ PG QK+E EE + L LQ + S S+ L +QK P Q LP
Sbjct: 3686 SQEEGDVPGVPQKREAEETAQKMAQLLYLQEESTPYKPQSPSIPSSHLRFQKAPVGQHLP 3745
Query: 1593 GV 1594
V
Sbjct: 3746 SV 3747
>gi|239750815 PREDICTED: StAR-related lipid transfer (START) domain
containing 9 [Homo sapiens]
Length = 4614
Score = 32.7 bits (73), Expect = 3.2
Identities = 20/62 (32%), Positives = 28/62 (45%)
Query: 1533 ASQDHRAPGPGQKQECEEETASADKQLVLQAQENMLVNVSFSLSLELLSYQKLPADQTLP 1592
+ ++ PG QK+E EE + L LQ + S S+ L +QK P Q LP
Sbjct: 3686 SQEEGDVPGVPQKREAEETAQKMAQLLYLQEESTPYKPQSPSIPSSHLRFQKAPVGQHLP 3745
Query: 1593 GV 1594
V
Sbjct: 3746 SV 3747
>gi|239745175 PREDICTED: StAR-related lipid transfer (START) domain
containing 9 [Homo sapiens]
Length = 4614
Score = 32.7 bits (73), Expect = 3.2
Identities = 20/62 (32%), Positives = 28/62 (45%)
Query: 1533 ASQDHRAPGPGQKQECEEETASADKQLVLQAQENMLVNVSFSLSLELLSYQKLPADQTLP 1592
+ ++ PG QK+E EE + L LQ + S S+ L +QK P Q LP
Sbjct: 3686 SQEEGDVPGVPQKREAEETAQKMAQLLYLQEESTPYKPQSPSIPSSHLRFQKAPVGQHLP 3745
Query: 1593 GV 1594
V
Sbjct: 3746 SV 3747
>gi|24234690 meiotic recombination 11 homolog A isoform 2 [Homo
sapiens]
Length = 680
Score = 32.3 bits (72), Expect = 4.2
Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 6/72 (8%)
Query: 687 VLSPHTDHEFILSFSPHELRDFHSVLQMVLEEVPEPV-SSEAESLGHSSYSVDDVIVLEI 745
VL+ H D F+P + ++ LE++ E + ++E E LG+S ++ L +
Sbjct: 313 VLANHPD-----IFNPDNPKVTQAIQSFCLEKIEEMLENAERERLGNSHQPEKPLVRLRV 367
Query: 746 EVKGSVEPFQVL 757
+ G EPF VL
Sbjct: 368 DYSGGFEPFSVL 379
>gi|5031923 meiotic recombination 11 homolog A isoform 1 [Homo
sapiens]
Length = 708
Score = 32.3 bits (72), Expect = 4.2
Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 6/72 (8%)
Query: 687 VLSPHTDHEFILSFSPHELRDFHSVLQMVLEEVPEPV-SSEAESLGHSSYSVDDVIVLEI 745
VL+ H D F+P + ++ LE++ E + ++E E LG+S ++ L +
Sbjct: 313 VLANHPD-----IFNPDNPKVTQAIQSFCLEKIEEMLENAERERLGNSHQPEKPLVRLRV 367
Query: 746 EVKGSVEPFQVL 757
+ G EPF VL
Sbjct: 368 DYSGGFEPFSVL 379
>gi|8394499 ubiquitin associated protein 1 [Homo sapiens]
Length = 502
Score = 32.3 bits (72), Expect = 4.2
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 20/76 (26%)
Query: 213 YTDTVPFHSAPK-----------GISLPGCSKLT------FSCEKRSVQKKELNKKLEDS 255
Y D VPF + K G SLP C ++ FS EK++++ E KK+E++
Sbjct: 16 YLDDVPFKTGDKFKTPAKVGLPIGFSLPDCLQVVREVQYDFSLEKKTIEWAEEIKKIEEA 75
Query: 256 CRK---KLAEFEDELD 268
R+ K+AE E +++
Sbjct: 76 EREAECKIAEAEAKVN 91
>gi|4758822 nephrin precursor [Homo sapiens]
Length = 1241
Score = 32.3 bits (72), Expect = 4.2
Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 12/91 (13%)
Query: 917 SSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLPVYAEVQKPHVYLQSSQVE 976
SSG LH R D L LHCQ+ E E + Y P +Q P ++V
Sbjct: 700 SSGALHLWNVTRADDGLYQLHCQNSEGTAEARLRLDV-HYAPTIRALQDP------TEVN 752
Query: 977 VRNLYLGVPTKTTITLINGTLLPTQFHWGKL 1007
V G T+ +LP F+W +L
Sbjct: 753 V-----GGSVDIVCTVDANPILPGMFNWERL 778
>gi|47578115 DEP domain containing 2 isoform a [Homo sapiens]
Length = 1606
Score = 32.3 bits (72), Expect = 4.2
Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 207 ISPEDYYTDTVPFHSAPKGISL--PGCSKLTFSCEKRSVQKKELNKKLEDSCRKKLAEFE 264
+SP Y T+ +AP G+SL L + ++ ++ +++ +KL + L E E
Sbjct: 982 LSPMVYIQHTITTMAAPSGLSLGQQDGHGLRYLLKEEDLETQDIYQKLLGKLQTALKEVE 1041
Query: 265 ---DELDHTVDSLTWNLTPKAKERTREPLKKASQPRNKNWMNHLRV 307
++D + S+T+ +PK + +T E + K N RV
Sbjct: 1042 MCVCQIDDLLSSITY--SPKLERKTSEGIIPTDSDNEKGERNSKRV 1085
>gi|50811889 centrosomal protein 192kDa [Homo sapiens]
Length = 1941
Score = 32.3 bits (72), Expect = 4.2
Identities = 25/117 (21%), Positives = 53/117 (45%), Gaps = 29/117 (24%)
Query: 612 DLTAQHFIRFEPENLRSTARKQLIIRNATHVELAFYWQIMKPNLQPLMPGETFSMDSIKC 671
DL HF+ + S+ ++ L ++NA ++E+ ++
Sbjct: 1056 DLQTMHFLA----KVASSRKQHLPLKNAGNIEVYLDIKV--------------------- 1090
Query: 672 YPDKETAFSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVLEEVPEPVSSEAE 728
P++ + FS+ P+ +L P +HE I+SF+P +D + + +L+ +P + E
Sbjct: 1091 -PEQGSHFSVDPKNLLLKPGEEHEVIVSFTP---KDPEACEERILKIFVQPFGPQYE 1143
>gi|153946403 BCL2/adenovirus E1B 19kD interacting protein 1 isoform
BNIP1-a [Homo sapiens]
Length = 194
Score = 32.3 bits (72), Expect = 4.2
Identities = 32/152 (21%), Positives = 65/152 (42%), Gaps = 18/152 (11%)
Query: 1465 PAQLSVELDYGGSMEFQCQASDLIPE-QPCSGVLSELVTTHHLKLTNTTEIPHYFRLMVS 1523
P + V + ++F + LI + + CSG LS L + T++ F+ +
Sbjct: 4 PQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELN-------TKVKEKFQQLRH 56
Query: 1524 RPFSVSQDGASQDHRAPGPGQKQECEEETASADKQLVLQAQENMLVNVSFSLSLELLSYQ 1583
R + Q QD + +KQ +E + KQ++ + + L S +++ L+
Sbjct: 57 RIQDLEQLAKEQDKES----EKQLLLQEVENHKKQMLRKTTKESLAQTSSTITESLMGIS 112
Query: 1584 KLPADQTLPGVDIQQSASGEREMVFTQNLLLE 1615
++ A Q +QQS + +V + +L+
Sbjct: 113 RMMAQQ------VQQSEEAMQSLVTSSRTILD 138
>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1230
Score = 32.0 bits (71), Expect = 5.5
Identities = 29/101 (28%), Positives = 37/101 (36%), Gaps = 17/101 (16%)
Query: 1645 GTCFVSQQRVREVYLMNLSGCRSYWTMLMGVVSCTSPRWWWKVCSVRSPAPC--GSGAKA 1702
GTC V+++ R M SG + PRW P PC GA
Sbjct: 1096 GTCLVTEESSRHSLKMKDSGLEKRGRL---------PRW--PPAERSRPLPCLDSPGAAH 1144
Query: 1703 PMM----RDTCCLTSPEAPPQPSAPGPSWRKNIAQGLGAAL 1739
P+ C LTSP+ PP S P + +A AL
Sbjct: 1145 PIRWIPHESRCWLTSPKKPPPHSGPSVTGSSPLAAVRALAL 1185
>gi|46370057 ring finger protein 216 isoform b [Homo sapiens]
Length = 866
Score = 32.0 bits (71), Expect = 5.5
Identities = 29/117 (24%), Positives = 47/117 (40%), Gaps = 15/117 (12%)
Query: 249 NKKLEDSCRKKLAEFEDEL----DHTVDSLTWNLTPKAKERTREPLKKASQPRNKNWMNH 304
N+ EDS + L+ + D ++ W P + ++P + +Q +
Sbjct: 141 NQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQQPREITNQVVPQE---- 196
Query: 305 LRVPQRELDRLLLARMESRNHFLKNPRFFPPNTRYGGKSLVFPPKKPAPIGEFQSTE 361
R P+ EL RLL H P F P + GG S P+ P+GEF+ +
Sbjct: 197 -RQPEAELGRLLF------QHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFEDQQ 246
>gi|46358403 ring finger protein 216 isoform a [Homo sapiens]
Length = 923
Score = 32.0 bits (71), Expect = 5.5
Identities = 29/117 (24%), Positives = 47/117 (40%), Gaps = 15/117 (12%)
Query: 249 NKKLEDSCRKKLAEFEDEL----DHTVDSLTWNLTPKAKERTREPLKKASQPRNKNWMNH 304
N+ EDS + L+ + D ++ W P + ++P + +Q +
Sbjct: 198 NQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQQPREITNQVVPQE---- 253
Query: 305 LRVPQRELDRLLLARMESRNHFLKNPRFFPPNTRYGGKSLVFPPKKPAPIGEFQSTE 361
R P+ EL RLL H P F P + GG S P+ P+GEF+ +
Sbjct: 254 -RQPEAELGRLLF------QHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFEDQQ 303
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,795,017
Number of Sequences: 37866
Number of extensions: 3794972
Number of successful extensions: 11550
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 11386
Number of HSP's gapped (non-prelim): 158
length of query: 1778
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1661
effective length of database: 13,817,196
effective search space: 22950362556
effective search space used: 22950362556
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.