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Search of human proteins with 14150134
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14150134 coiled-coil-helix-coiled-coil-helix domain
containing 6 [Homo sapiens]
(235 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14150134 coiled-coil-helix-coiled-coil-helix domain containin... 466 e-131
gi|8923390 coiled-coil-helix-coiled-coil-helix domain containing... 143 1e-34
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 40 0.001
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 40 0.002
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 40 0.002
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap... 39 0.003
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap... 39 0.003
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 39 0.004
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 39 0.004
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 39 0.004
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 39 0.004
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 39 0.005
gi|31982906 cingulin-like 1 [Homo sapiens] 38 0.007
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 38 0.009
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 37 0.015
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 37 0.015
gi|162287076 RhoA/RAC/CDC42 exchange factor isoform 3 [Homo sapi... 37 0.015
gi|58535453 CDK5 regulatory subunit associated protein 2 isoform... 37 0.019
gi|58535451 CDK5 regulatory subunit associated protein 2 isoform... 37 0.019
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 37 0.019
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 37 0.019
gi|156104908 myosin heavy chain 6 [Homo sapiens] 37 0.019
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 36 0.025
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 36 0.025
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 36 0.025
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 36 0.025
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 36 0.025
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 36 0.025
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 36 0.025
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 36 0.033
>gi|14150134 coiled-coil-helix-coiled-coil-helix domain containing 6
[Homo sapiens]
Length = 235
Score = 466 bits (1198), Expect = e-131
Identities = 235/235 (100%), Positives = 235/235 (100%)
Query: 1 MGSTESSEGRRVSFGVDEEERVRVLQGVRLSENVVNRMKEPSSPPPAPTSSTFGLQDGNL 60
MGSTESSEGRRVSFGVDEEERVRVLQGVRLSENVVNRMKEPSSPPPAPTSSTFGLQDGNL
Sbjct: 1 MGSTESSEGRRVSFGVDEEERVRVLQGVRLSENVVNRMKEPSSPPPAPTSSTFGLQDGNL 60
Query: 61 RAPHKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASL 120
RAPHKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASL
Sbjct: 61 RAPHKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASL 120
Query: 121 PTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEA 180
PTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEA
Sbjct: 121 PTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEA 180
Query: 181 ASKMESTIKPRRVEPVCSGLQAQILHCYRDRPHEVLLCSDLVKAYQRCVSAAHKG 235
ASKMESTIKPRRVEPVCSGLQAQILHCYRDRPHEVLLCSDLVKAYQRCVSAAHKG
Sbjct: 181 ASKMESTIKPRRVEPVCSGLQAQILHCYRDRPHEVLLCSDLVKAYQRCVSAAHKG 235
>gi|8923390 coiled-coil-helix-coiled-coil-helix domain containing 3
[Homo sapiens]
Length = 227
Score = 143 bits (360), Expect = 1e-34
Identities = 84/236 (35%), Positives = 130/236 (55%), Gaps = 22/236 (9%)
Query: 1 MGSTESSEGRRVSFGVDEEERVRVLQGVRLSENVVNRMKE--PSSPPPAPTSSTFG--LQ 56
MG T S+ RRV+F DE E + V++G+RLSENV++RMKE PS S +G +
Sbjct: 1 MGGTTST--RRVTFEADENENITVVKGIRLSENVIDRMKESSPSGSKSQRYSGAYGASVS 58
Query: 57 DGNLRAPHKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHS 116
D L+ E + +K+ K ++E AA ++L + RER + +
Sbjct: 59 DEELKRRVAEELALEQAKKESEDQKRLKQA-KELDRERAAANEQLTRAILRERICSEE-- 115
Query: 117 KASLPTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQ 176
E K+ LAR+LE ++ L+++D FYKEQL R+E +++E Y++++EQ
Sbjct: 116 -------------ERAKAKHLARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQ 162
Query: 177 FHEAASKMESTIKPRRVEPVCSGLQAQILHCYRDRPHEVLLCSDLVKAYQRCVSAA 232
+ +AA ++E+ K PVC+ LQA+IL CYR+ H+ L CS L Y CV+ A
Sbjct: 163 YQKAAEEVEAKFKRYESHPVCADLQAKILQCYRENTHQTLKCSALATQYMHCVNHA 218
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 40.4 bits (93), Expect = 0.001
Identities = 40/175 (22%), Positives = 73/175 (41%), Gaps = 29/175 (16%)
Query: 17 DEEERVRVLQGVRLSENVVNRMKEPSSPPPAPTSSTFGLQDGNL-----RAPHKESTLPR 71
+E E+ G RL+ V + E ++ ++T QD L +A K++ L +
Sbjct: 483 EELEQASQAHGARLTAQVASLTSELTT-----LNATIQQQDQELAGLKQQAKEKQAQLAQ 537
Query: 72 SGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEE 131
+ Q G++ V++ + +L +VA+++ H++
Sbjct: 538 TLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQ-------------- 583
Query: 132 QKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMES 186
+LA E REA LR RD K QLE +E++ A ++ +Q A +S
Sbjct: 584 ----QLATAAEEREASLRERDAALK-QLEALEKEKAAKLEILQQQLQVANEARDS 633
Score = 32.3 bits (72), Expect = 0.36
Identities = 32/127 (25%), Positives = 65/127 (51%), Gaps = 10/127 (7%)
Query: 88 KRYEQEHAAIQ-DKLFQVAKREREAATKHSKASLPTG--EGSISHEEQKSVRLARELESR 144
++Y QE AA++ D ++A+ +REA + + + T EG+ ++ R E +
Sbjct: 1474 EKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKL 1533
Query: 145 EAELRRRDTFYKEQLERIE---RKNAEMYKLSSEQFHE----AASKMESTIKPRRVEPVC 197
A++ + + F +EQ +++E +K A+ + S Q + A ES + +R++
Sbjct: 1534 TAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQL 1593
Query: 198 SGLQAQI 204
+ LQAQ+
Sbjct: 1594 NELQAQL 1600
Score = 27.7 bits (60), Expect = 8.9
Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Query: 89 RYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRLARELESREAEL 148
R EQ+ A ++++ Q K + + + K SL +GS+ E++++ E + +EL
Sbjct: 681 RSEQQKATEKERVAQ-EKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISEL 739
Query: 149 RRRDTFYKEQLERIERKNAE 168
+ EQ +R ERK E
Sbjct: 740 KAETRSLVEQHKR-ERKELE 758
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 39.7 bits (91), Expect = 0.002
Identities = 25/105 (23%), Positives = 52/105 (49%), Gaps = 1/105 (0%)
Query: 106 KREREAATKHSKASLPTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERK 165
+++ EA +++L E S+ HEE K +R E +AE+ R+ E++E+ +R
Sbjct: 1530 RKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRN 1589
Query: 166 NAEMY-KLSSEQFHEAASKMESTIKPRRVEPVCSGLQAQILHCYR 209
+ + L + E S+ E+ +++E + ++ Q+ H R
Sbjct: 1590 HLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANR 1634
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 39.7 bits (91), Expect = 0.002
Identities = 33/137 (24%), Positives = 68/137 (49%), Gaps = 10/137 (7%)
Query: 83 MKEGVKRYEQEHAAIQDKLFQVAKR--EREAATK---HSKASLPTG----EGSISHEEQK 133
+K K +QE + + +++ + K E E K H K+ L T E S+ HEE K
Sbjct: 1502 LKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGK 1561
Query: 134 SVRLARELESREAELRRRDTFYKEQLERIERKNAEMYK-LSSEQFHEAASKMESTIKPRR 192
+R+ EL ++E+ R+ E+L++++R + + + + S E S+ ++ ++
Sbjct: 1562 ILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKK 1621
Query: 193 VEPVCSGLQAQILHCYR 209
+E + ++ Q+ H R
Sbjct: 1622 MEGDLNEMEIQLNHANR 1638
Score = 28.1 bits (61), Expect = 6.8
Identities = 25/114 (21%), Positives = 49/114 (42%), Gaps = 10/114 (8%)
Query: 83 MKEGVKRYEQEHAAIQDKL---------FQVAKREREAATKHSKASLPTGEGSISHEEQK 133
+ E +K+ E E + +Q K+ Q +E +A + + + S + E++
Sbjct: 1080 LNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1139
Query: 134 SVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMEST 187
L+RELE L Q+E +++ AE K+ + E+ + E+T
Sbjct: 1140 RSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRD-LEESTLQHEAT 1192
>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
Length = 2603
Score = 39.3 bits (90), Expect = 0.003
Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 2/78 (2%)
Query: 104 VAKREREAATKHSKASLPTGEGSIS--HEEQKSVRLARELESREAELRRRDTFYKEQLER 161
V ++R+AA + AS+ E + EE + + LA + E R+ + R++ + +LE
Sbjct: 1442 VQAKDRQAAEANKNASILLEELDLEKLREESRRLALAAKREKRKEKRRKKKEEQRRKLEE 1501
Query: 162 IERKNAEMYKLSSEQFHE 179
IE KN E ++L + Q E
Sbjct: 1502 IEAKNKENFELQAAQEKE 1519
Score = 29.3 bits (64), Expect = 3.1
Identities = 33/133 (24%), Positives = 62/133 (46%), Gaps = 23/133 (17%)
Query: 41 PSSP--PPAPTSSTFGLQDGNLRAPHKESTLPRS-----GSSGGQQPSGMKEGVKRYEQE 93
P P PPA ++T +++ S LP + G Q P + E
Sbjct: 758 PQEPDKPPANVATTLPIRNKAASKQKSSSHLPANSQDVQGYITNQSPESIVEEA------ 811
Query: 94 HAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRLAREL-ESREAELRRRD 152
Q KL ++ +R +EA K+ A L + E ++H +Q + EL ++RE +++++
Sbjct: 812 ----QGKLTELEQRIKEAIEKN--AQLQSLE--LAHADQLTKEKIEELNKTREEQIQKKQ 863
Query: 153 TFYKEQLERIERK 165
E+L+++ER+
Sbjct: 864 KIL-EELQKVERE 875
>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sapiens]
Length = 2352
Score = 39.3 bits (90), Expect = 0.003
Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 2/78 (2%)
Query: 104 VAKREREAATKHSKASLPTGEGSIS--HEEQKSVRLARELESREAELRRRDTFYKEQLER 161
V ++R+AA + AS+ E + EE + + LA + E R+ + R++ + +LE
Sbjct: 1191 VQAKDRQAAEANKNASILLEELDLEKLREESRRLALAAKREKRKEKRRKKKEEQRRKLEE 1250
Query: 162 IERKNAEMYKLSSEQFHE 179
IE KN E ++L + Q E
Sbjct: 1251 IEAKNKENFELQAAQEKE 1268
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 38.9 bits (89), Expect = 0.004
Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 9/105 (8%)
Query: 88 KRYEQEHAAIQDKLFQVAKREREAATK--HSKASLPTGEGSISHEEQKSVRLARELESRE 145
+R E + +Q + + EAA K ++A L G+++ E K++RL++EL S E
Sbjct: 1280 RRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTE 1339
Query: 146 AELRRRDTFYKEQL-------ERIERKNAEMYKLSSEQFHEAASK 183
A+L +E+ R+ AE L + EAA++
Sbjct: 1340 AQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAAR 1384
Score = 29.6 bits (65), Expect = 2.3
Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
Query: 136 RLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMESTIKPRRVEP 195
+L ELE +A++ +E ++++ + A+M +L E S+ E + R E
Sbjct: 1646 KLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEK 1705
Query: 196 VCSGLQAQILHCYRDRPHEVLLCSD 220
GL+A++L R E L SD
Sbjct: 1706 RLKGLEAEVL-----RLQEELAASD 1725
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 38.9 bits (89), Expect = 0.004
Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 9/105 (8%)
Query: 88 KRYEQEHAAIQDKLFQVAKREREAATK--HSKASLPTGEGSISHEEQKSVRLARELESRE 145
+R E + +Q + + EAA K ++A L G+++ E K++RL++EL S E
Sbjct: 1272 RRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTE 1331
Query: 146 AELRRRDTFYKEQL-------ERIERKNAEMYKLSSEQFHEAASK 183
A+L +E+ R+ AE L + EAA++
Sbjct: 1332 AQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAAR 1376
Score = 29.6 bits (65), Expect = 2.3
Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
Query: 136 RLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMESTIKPRRVEP 195
+L ELE +A++ +E ++++ + A+M +L E S+ E + R E
Sbjct: 1638 KLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEK 1697
Query: 196 VCSGLQAQILHCYRDRPHEVLLCSD 220
GL+A++L R E L SD
Sbjct: 1698 RLKGLEAEVL-----RLQEELAASD 1717
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 38.9 bits (89), Expect = 0.004
Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 9/105 (8%)
Query: 88 KRYEQEHAAIQDKLFQVAKREREAATK--HSKASLPTGEGSISHEEQKSVRLARELESRE 145
+R E + +Q + + EAA K ++A L G+++ E K++RL++EL S E
Sbjct: 1313 RRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTE 1372
Query: 146 AELRRRDTFYKEQL-------ERIERKNAEMYKLSSEQFHEAASK 183
A+L +E+ R+ AE L + EAA++
Sbjct: 1373 AQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAAR 1417
Score = 29.6 bits (65), Expect = 2.3
Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
Query: 136 RLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMESTIKPRRVEP 195
+L ELE +A++ +E ++++ + A+M +L E S+ E + R E
Sbjct: 1679 KLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEK 1738
Query: 196 VCSGLQAQILHCYRDRPHEVLLCSD 220
GL+A++L R E L SD
Sbjct: 1739 RLKGLEAEVL-----RLQEELAASD 1758
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 38.9 bits (89), Expect = 0.004
Identities = 31/132 (23%), Positives = 65/132 (49%), Gaps = 10/132 (7%)
Query: 88 KRYEQEHAAIQDKLFQVAKREREAA-----TKHSKASLPTG----EGSISHEEQKSVRLA 138
K ++E + + +++ + K +EA + K+ L EGS+ HEE K +R+
Sbjct: 1507 KNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQ 1566
Query: 139 RELESREAELRRRDTFYKEQLERIERKNAEMYK-LSSEQFHEAASKMESTIKPRRVEPVC 197
EL ++EL R+ E++E+++R + + L S E S+ ++ +++E
Sbjct: 1567 LELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDL 1626
Query: 198 SGLQAQILHCYR 209
+ ++ Q+ H R
Sbjct: 1627 NEMEIQLGHSNR 1638
Score = 32.3 bits (72), Expect = 0.36
Identities = 23/92 (25%), Positives = 47/92 (51%), Gaps = 6/92 (6%)
Query: 91 EQEHAAIQDKLFQV-AKREREAATKHS----KASLPTGEGSISHE-EQKSVRLARELESR 144
E+ ++D+ ++ AK E++ H KA L T G +SH E+K +++ +S+
Sbjct: 1250 ERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSK 1309
Query: 145 EAELRRRDTFYKEQLERIERKNAEMYKLSSEQ 176
+A ++ + ++ E + KNA + L S +
Sbjct: 1310 QALTQQLEELKRQMEEETKAKNAMAHALQSSR 1341
Score = 30.4 bits (67), Expect = 1.4
Identities = 45/190 (23%), Positives = 78/190 (41%), Gaps = 21/190 (11%)
Query: 18 EEERVRVLQGVRLSENVVNRMKEPSSPPPAPTSSTFGL--QDGNLRAPHKESTLPRSGSS 75
+E + L +++ E+ VN + + ++ T G Q+ LRA + + G
Sbjct: 1004 QEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDL 1063
Query: 76 GGQQPSGM---------KEGVKRYEQEHAAIQDKLF--QVAKREREAATKHSKASLPTGE 124
Q S M +E +K+ E E + +Q K+ QV + + K +A + E
Sbjct: 1064 KMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELE 1123
Query: 125 GSISHE-------EQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQF 177
I E E++ LARELE L Q+E +++ AE K+ +
Sbjct: 1124 EEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRD-L 1182
Query: 178 HEAASKMEST 187
EA + E+T
Sbjct: 1183 EEATLQHEAT 1192
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 38.5 bits (88), Expect = 0.005
Identities = 36/156 (23%), Positives = 73/156 (46%), Gaps = 20/156 (12%)
Query: 55 LQDGNLRAPHKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATK 114
L+ N + S L + GG+Q +++ K+ EQE IQ AA +
Sbjct: 1501 LRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQ------------AALE 1548
Query: 115 HSKASLPTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYK-LS 173
++ASL HEE K +R+ EL ++E+ R+ E++++++R + + + +
Sbjct: 1549 EAEASL-------EHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQ 1601
Query: 174 SEQFHEAASKMESTIKPRRVEPVCSGLQAQILHCYR 209
S E S+ ++ +++E + ++ Q+ H R
Sbjct: 1602 STLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANR 1637
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 38.1 bits (87), Expect = 0.007
Identities = 39/175 (22%), Positives = 78/175 (44%), Gaps = 32/175 (18%)
Query: 84 KEGVKRYEQEHAAIQDKLFQVAKREREA--ATKHSKASLPTGEGSIS----HEEQKSVRL 137
KE +K+YE E +++ L K E+EA A + + L +G++S ++Q S +L
Sbjct: 863 KETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKL 922
Query: 138 ARELESREAELRRRDTFYKEQ------LERIERKNAEMYKLS--------------SEQF 177
E E +E R ++ E+ +E+++++ A++ + S E+
Sbjct: 923 KEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKN 982
Query: 178 HEAASKMESTIKPRRVEPVCSGLQAQILHCYRDRPHEVLLCSDLVKAYQRCVSAA 232
++M+ +K + +E S L A + E+ L + ++ YQR A
Sbjct: 983 RRELAEMQRQLKEKTLEAEKSRLTAMKMQ------DEMRLMEEELRDYQRAQDEA 1031
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 37.7 bits (86), Expect = 0.009
Identities = 41/193 (21%), Positives = 82/193 (42%), Gaps = 10/193 (5%)
Query: 10 RRVSFGVDEEERVRVLQGVRLSENVVNRMKEPSSPPPAPTSSTFGLQDGNLRAPHKESTL 69
R + + E+E++R + R E + ++ +++ + +E +
Sbjct: 380 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM 439
Query: 70 PRSGSSGGQQPSGMKEGVKRYEQEHAAIQD-KLFQVAKREREAATKHSKASLPTGEGSI- 127
R +Q ++E KR EQE Q+ K+ + + R+ H + + E +
Sbjct: 440 WRQEEKIHEQEK-IREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVW 498
Query: 128 -----SHEEQKSVRLARELESREAE-LRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAA 181
H++++ +R E R+ E +R ++ +EQ E+I R+ EM + E+ E
Sbjct: 499 RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKI-REQEEMMQEQEEKMGEQE 557
Query: 182 SKMESTIKPRRVE 194
KM+ K RR E
Sbjct: 558 EKMQEQEKMRRQE 570
Score = 32.0 bits (71), Expect = 0.47
Identities = 19/90 (21%), Positives = 49/90 (54%), Gaps = 4/90 (4%)
Query: 91 EQEHAAIQDKLFQVAKREREAATK-HSKASLPTGEGSISHEEQKSVRLARELESREAELR 149
E++ +++ +++ ++ RE K H + + E +E++ +R + + +EA++
Sbjct: 362 EEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEK--RQEEEKIREQEKRQEQEAKMW 419
Query: 150 RRDTFYKEQLERIERKNAEMYKLSSEQFHE 179
R++ +EQ E+I + +M++ E+ HE
Sbjct: 420 RQEEKIREQEEKIREQEKKMWR-QEEKIHE 448
Score = 30.4 bits (67), Expect = 1.4
Identities = 23/111 (20%), Positives = 51/111 (45%), Gaps = 7/111 (6%)
Query: 84 KEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRLARELES 143
+E ++ +E++ ++K+ RE+E + + + E + +E+K R +
Sbjct: 306 EEKIQEWEEKIQEQEEKI-----REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
Query: 144 REAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMESTIKPRRVE 194
+E ++RR + E+ E+I +M++ E+ E K + K R E
Sbjct: 361 KEEKMRRLEEMMWEKEEKIRELEEKMHE--QEKIREQEEKRQEEEKIREQE 409
Score = 30.4 bits (67), Expect = 1.4
Identities = 27/177 (15%), Positives = 73/177 (41%), Gaps = 16/177 (9%)
Query: 18 EEERVRVLQGVRLSENVVNRMKEPSSPPPAPTSSTFGLQDGNLRAPHKESTLPRSGSSGG 77
++E++ + +R E V R +E + D + +E + R
Sbjct: 480 QKEKMHEQEKIRKQEEKVWRQEEK-------------MHDQEEKIREQEEKMWRQEEKIR 526
Query: 78 QQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRL 137
+Q ++E ++ ++ +Q++ ++ ++E + + + E I +E+K
Sbjct: 527 EQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM---QEQEKMRRQEEKIREQEEKIREQ 583
Query: 138 ARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMESTIKPRRVE 194
++ +E ++ ++ +EQ E ++ + +M++ + + E K RR E
Sbjct: 584 KEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 640
Score = 29.6 bits (65), Expect = 2.3
Identities = 15/71 (21%), Positives = 35/71 (49%)
Query: 124 EGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASK 183
E + +E+K +++ +E ++R ++ +EQ E++ R+ M++ + +
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 358
Query: 184 MESTIKPRRVE 194
E K RR+E
Sbjct: 359 WEKEEKMRRLE 369
Score = 28.5 bits (62), Expect = 5.2
Identities = 17/97 (17%), Positives = 43/97 (44%)
Query: 98 QDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRLARELESREAELRRRDTFYKE 157
+++L+ +++E + + E I +E+K ++ +E ++RR++ E
Sbjct: 287 ENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWE 346
Query: 158 QLERIERKNAEMYKLSSEQFHEAASKMESTIKPRRVE 194
+ E++ R+ M++ + E K R +E
Sbjct: 347 KEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELE 383
Score = 27.7 bits (60), Expect = 8.9
Identities = 21/115 (18%), Positives = 46/115 (40%), Gaps = 10/115 (8%)
Query: 65 KESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGE 124
+E + G+Q M+E K QE RE+E + K + E
Sbjct: 542 QEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKI----------REQEEKIREQKEKIREQE 591
Query: 125 GSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHE 179
I +E+K ++ +E ++ ++ EQ E+++ + +M + + + +
Sbjct: 592 EKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 646
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 37.0 bits (84), Expect = 0.015
Identities = 35/156 (22%), Positives = 74/156 (47%), Gaps = 20/156 (12%)
Query: 55 LQDGNLRAPHKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATK 114
L+ N + S L + GG++ +++ K+ EQE K E +AA +
Sbjct: 1502 LKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQE------------KSELQAALE 1549
Query: 115 HSKASLPTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYK-LS 173
++ASL HEE K +R+ EL ++E+ R+ E++++++R + + + +
Sbjct: 1550 EAEASL-------EHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQ 1602
Query: 174 SEQFHEAASKMESTIKPRRVEPVCSGLQAQILHCYR 209
S E S+ ++ +++E + ++ Q+ H R
Sbjct: 1603 STLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1638
Score = 30.0 bits (66), Expect = 1.8
Identities = 26/114 (22%), Positives = 49/114 (42%), Gaps = 10/114 (8%)
Query: 83 MKEGVKRYEQEHAAIQDKL---------FQVAKREREAATKHSKASLPTGEGSISHEEQK 133
+ E +K+ E E + +Q K+ Q +E +A + + + S + E++
Sbjct: 1080 LDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1139
Query: 134 SVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMEST 187
L+RELE L Q+E +++ AE K+ + EA + E+T
Sbjct: 1140 RSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRD-LEEATLQHEAT 1192
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 37.0 bits (84), Expect = 0.015
Identities = 32/110 (29%), Positives = 52/110 (47%), Gaps = 14/110 (12%)
Query: 88 KRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRLARELESREAE 147
KR E++HA +++K +RE E +H + + E QK +ARE RE
Sbjct: 104 KRKEKKHARVKEK-----EREHERRKRHREEQ---DKARREWERQKRREMAREHSRRE-- 153
Query: 148 LRRRD--TFYKEQLERIERKNAEMYKLSSEQFHEAASK-MESTIKPRRVE 194
R D ++++LE++ERK K+ +Q + K E + RR E
Sbjct: 154 -RGNDGVCLFRDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKE 202
Score = 28.9 bits (63), Expect = 4.0
Identities = 32/153 (20%), Positives = 52/153 (33%), Gaps = 26/153 (16%)
Query: 42 SSPPPAPTSSTFGLQDGNLRAPHKESTLPR-------------------SGSSGGQQPSG 82
S PP P F L DG R P KE + + SS + SG
Sbjct: 230 SRSPPRPPRERFELGDG--RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG 287
Query: 83 MKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRLARELE 142
+E E+E +++ ++ E + + TG S EQ + ++ E
Sbjct: 288 SEE-----EEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 342
Query: 143 SREAELRRRDTFYKEQLERIERKNAEMYKLSSE 175
S + E + R +R + E + E
Sbjct: 343 SEDEERENENHLLVVPESRFDRDSGESEEAEEE 375
>gi|162287076 RhoA/RAC/CDC42 exchange factor isoform 3 [Homo
sapiens]
Length = 619
Score = 37.0 bits (84), Expect = 0.015
Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 10/99 (10%)
Query: 38 MKEPSSPPPAPTSSTFGLQDGNLRA---PHKESTLPRS--GSSGGQQPSGMKEGVKRYEQ 92
MK P P P T G+ G LRA P +E RS G G + S EG R ++
Sbjct: 1 MKPPDRPAPGRTDRILGVMGGMLRACALPGQEGPPRRSPLGLVGTEPESERTEGDHRRDR 60
Query: 93 EH----AAIQDKLFQVAKRERE-AATKHSKASLPTGEGS 126
EH A+Q + + +A E +A+ S + P+G S
Sbjct: 61 EHEVLAGALQPESYSIAGSEGSISASAASGLAAPSGPSS 99
>gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b
[Homo sapiens]
Length = 1814
Score = 36.6 bits (83), Expect = 0.019
Identities = 28/101 (27%), Positives = 49/101 (48%), Gaps = 4/101 (3%)
Query: 78 QQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEG--SISHEEQKSV 135
QQP G K + E++ ++ ++L QV K+E++ T H SL + ++ E K
Sbjct: 531 QQPPGSKTIFSK-EKKQSSDYEELIQVLKKEQDIYT-HLVKSLQESDSINNLQAELNKIF 588
Query: 136 RLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQ 176
L ++LE + +EQ+ I R+ E + L S+Q
Sbjct: 589 ALRKQLEQDVLSYQNLRKTLEEQISEIRRREEESFSLYSDQ 629
>gi|58535451 CDK5 regulatory subunit associated protein 2 isoform a
[Homo sapiens]
Length = 1893
Score = 36.6 bits (83), Expect = 0.019
Identities = 28/101 (27%), Positives = 49/101 (48%), Gaps = 4/101 (3%)
Query: 78 QQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEG--SISHEEQKSV 135
QQP G K + E++ ++ ++L QV K+E++ T H SL + ++ E K
Sbjct: 531 QQPPGSKTIFSK-EKKQSSDYEELIQVLKKEQDIYT-HLVKSLQESDSINNLQAELNKIF 588
Query: 136 RLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQ 176
L ++LE + +EQ+ I R+ E + L S+Q
Sbjct: 589 ALRKQLEQDVLSYQNLRKTLEEQISEIRRREEESFSLYSDQ 629
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 36.6 bits (83), Expect = 0.019
Identities = 35/156 (22%), Positives = 74/156 (47%), Gaps = 20/156 (12%)
Query: 55 LQDGNLRAPHKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATK 114
L+ N + S L + GG++ +++ K+ EQE K E +AA +
Sbjct: 1504 LKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQE------------KCELQAALE 1551
Query: 115 HSKASLPTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYK-LS 173
++ASL HEE K +R+ EL ++E+ R+ E++++++R + + + +
Sbjct: 1552 EAEASL-------EHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQ 1604
Query: 174 SEQFHEAASKMESTIKPRRVEPVCSGLQAQILHCYR 209
S E S+ ++ +++E + ++ Q+ H R
Sbjct: 1605 STLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1640
Score = 28.9 bits (63), Expect = 4.0
Identities = 26/114 (22%), Positives = 49/114 (42%), Gaps = 10/114 (8%)
Query: 83 MKEGVKRYEQEHAAIQDKL---------FQVAKREREAATKHSKASLPTGEGSISHEEQK 133
+ E +K+ E E + +Q K+ Q +E +A + + + S + E++
Sbjct: 1082 LDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1141
Query: 134 SVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMEST 187
L+RELE L Q+E +++ AE K+ + EA + E+T
Sbjct: 1142 RSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRD-LEEATLQHEAT 1194
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 36.6 bits (83), Expect = 0.019
Identities = 35/156 (22%), Positives = 74/156 (47%), Gaps = 20/156 (12%)
Query: 55 LQDGNLRAPHKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATK 114
L+ N + S L + GG++ +++ K+ EQE K E +AA +
Sbjct: 1504 LKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQE------------KCELQAALE 1551
Query: 115 HSKASLPTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYK-LS 173
++ASL HEE K +R+ EL ++E+ R+ E++++++R + + + +
Sbjct: 1552 EAEASL-------EHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQ 1604
Query: 174 SEQFHEAASKMESTIKPRRVEPVCSGLQAQILHCYR 209
S E S+ ++ +++E + ++ Q+ H R
Sbjct: 1605 STLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1640
Score = 28.9 bits (63), Expect = 4.0
Identities = 26/114 (22%), Positives = 49/114 (42%), Gaps = 10/114 (8%)
Query: 83 MKEGVKRYEQEHAAIQDKL---------FQVAKREREAATKHSKASLPTGEGSISHEEQK 133
+ E +K+ E E + +Q K+ Q +E +A + + + S + E++
Sbjct: 1082 LDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQ 1141
Query: 134 SVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMEST 187
L+RELE L Q+E +++ AE K+ + EA + E+T
Sbjct: 1142 RSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRD-LEEATLQHEAT 1194
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 36.6 bits (83), Expect = 0.019
Identities = 24/105 (22%), Positives = 50/105 (47%), Gaps = 1/105 (0%)
Query: 106 KREREAATKHSKASLPTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERK 165
+++ E +++L E S+ HEE K +R E +AE+ R+ E++E+ +R
Sbjct: 1532 RKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRN 1591
Query: 166 NAEMY-KLSSEQFHEAASKMESTIKPRRVEPVCSGLQAQILHCYR 209
+ + L + E S+ E +++E + ++ Q+ H R
Sbjct: 1592 HQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANR 1636
>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
sapiens]
Length = 693
Score = 36.2 bits (82), Expect = 0.025
Identities = 45/200 (22%), Positives = 78/200 (39%), Gaps = 28/200 (14%)
Query: 18 EEERVRVLQGVRLSENVVNRMKE-----PSSPPPAPTSSTFGLQD-------------GN 59
+EE+ R + ++ E ++ +K PS PPA TS LQD G
Sbjct: 258 KEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGK 317
Query: 60 LRAP-HKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKA 118
L++ L Q+ +E ++ E + Q++L + +R RE K
Sbjct: 318 LQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLRE----QQKT 373
Query: 119 SLPTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFH 178
GE + +EQ+ + L E L++++ +Q ER+ +K + K Q
Sbjct: 374 LQEQGE-RLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQK----QEE 428
Query: 179 EAASKMESTIKPRRVEPVCS 198
A + + EP CS
Sbjct: 429 RLALSQNHKLDKQLAEPQCS 448
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 36.2 bits (82), Expect = 0.025
Identities = 45/200 (22%), Positives = 78/200 (39%), Gaps = 28/200 (14%)
Query: 18 EEERVRVLQGVRLSENVVNRMKE-----PSSPPPAPTSSTFGLQD-------------GN 59
+EE+ R + ++ E ++ +K PS PPA TS LQD G
Sbjct: 258 KEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGK 317
Query: 60 LRAP-HKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKA 118
L++ L Q+ +E ++ E + Q++L + +R RE K
Sbjct: 318 LQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLRE----QQKT 373
Query: 119 SLPTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFH 178
GE + +EQ+ + L E L++++ +Q ER+ +K + K Q
Sbjct: 374 LQEQGE-RLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQK----QEE 428
Query: 179 EAASKMESTIKPRRVEPVCS 198
A + + EP CS
Sbjct: 429 RLALSQNHKLDKQLAEPQCS 448
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 36.2 bits (82), Expect = 0.025
Identities = 21/117 (17%), Positives = 55/117 (47%), Gaps = 2/117 (1%)
Query: 78 QQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRL 137
+Q ++E K+ ++ I+++ + ++E + + K + E + +E+K R
Sbjct: 436 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGK--MCEQEAKMQEQEEKMRRQ 493
Query: 138 ARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMESTIKPRRVE 194
++ +E ++R ++ +EQ E ++ + +M++ + + E K RR E
Sbjct: 494 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 550
Score = 33.5 bits (75), Expect = 0.16
Identities = 22/106 (20%), Positives = 48/106 (45%), Gaps = 4/106 (3%)
Query: 89 RYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRLARELESREAEL 148
R ++E Q+++ Q E+E + + E + +E+K R ++ +E ++
Sbjct: 393 REQEEKIREQEEMMQ----EQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI 448
Query: 149 RRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMESTIKPRRVE 194
R ++ +EQ E ++ + +M + + + A E K RR E
Sbjct: 449 REQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQE 494
Score = 32.3 bits (72), Expect = 0.36
Identities = 17/92 (18%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Query: 78 QQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRL 137
+Q + M+E ++ ++ I+++ ++ RE+E + + + E + +E+K
Sbjct: 478 EQEAKMQEQEEKMRRQEEKIREQEKKI--REQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 535
Query: 138 ARELESREAELRRRDTFYKEQLERIERKNAEM 169
+++ +E ++RR++ +EQ R+ ++ +M
Sbjct: 536 EEKMQEQEEKMRRQEEKMREQEVRLRQQEEKM 567
Score = 30.0 bits (66), Expect = 1.8
Identities = 22/95 (23%), Positives = 49/95 (51%), Gaps = 4/95 (4%)
Query: 91 EQEHAAIQDKLFQVAKREREAATK-HSKASLPTGEGSISHEEQKSVRLARELESREAELR 149
E++ ++ +++ ++ RE K H + + E +E++ +R + + +EA++
Sbjct: 329 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK--RQEEEKIREQEKRQEQEAKMW 386
Query: 150 RRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKM 184
R++ +EQ E+I R+ EM + E+ E KM
Sbjct: 387 RQEEKIREQEEKI-REQEEMMQEQEEKMGEQEEKM 420
Score = 28.9 bits (63), Expect = 4.0
Identities = 14/65 (21%), Positives = 33/65 (50%)
Query: 130 EEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMESTIK 189
+E+K R +++ RE +++ ++ +EQ E++ R+ M++ + + E K
Sbjct: 286 QEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 345
Query: 190 PRRVE 194
R +E
Sbjct: 346 IRELE 350
Score = 28.1 bits (61), Expect = 6.8
Identities = 19/86 (22%), Positives = 38/86 (44%), Gaps = 2/86 (2%)
Query: 109 REAATKHSKASLPTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAE 168
+E + + + E I +E+K R + +E ++RR++ E+ E+I +
Sbjct: 293 QEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 352
Query: 169 MYKLSSEQFHEAASKMESTIKPRRVE 194
M++ E+ E K + K R E
Sbjct: 353 MHE--QEKIREQEEKRQEEEKIREQE 376
Score = 27.7 bits (60), Expect = 8.9
Identities = 24/137 (17%), Positives = 61/137 (44%), Gaps = 13/137 (9%)
Query: 65 KESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKRE-----REAATKHSKAS 119
+E + R +Q ++E ++ ++ +Q++ ++ ++E +EA + +
Sbjct: 430 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEK 489
Query: 120 LPTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHE 179
+ E I +E+K + +E ++R ++ +EQ E++ + +M + E+ E
Sbjct: 490 MRRQEEKIREQEKK-------IREQEEKIREQEEMMQEQEEKMWEQEEKMCE-QEEKMQE 541
Query: 180 AASKMESTIKPRRVEPV 196
KM + R + V
Sbjct: 542 QEEKMRRQEEKMREQEV 558
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 36.2 bits (82), Expect = 0.025
Identities = 31/112 (27%), Positives = 50/112 (44%), Gaps = 7/112 (6%)
Query: 71 RSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAK-------REREAATKHSKASLPTG 123
+S G Q+ + + V R EQE +VA+ R E A + + LPT
Sbjct: 766 KSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTL 825
Query: 124 EGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSE 175
S +++ +L+R+L RE EL + + Q+E +ER E L+ E
Sbjct: 826 RHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKE 877
Score = 33.1 bits (74), Expect = 0.21
Identities = 43/176 (24%), Positives = 76/176 (43%), Gaps = 23/176 (13%)
Query: 59 NLRAPHKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKA 118
NL P LP + + ++E + +QE + ++D L Q E A K++
Sbjct: 58 NLSQPESPVLLPATEMAS---LLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAV 114
Query: 119 S------LPTGEGSISHEE-----QKSVRLARELESREAELRRRDTFYKEQLERIERKNA 167
S L G + +E ++SV L R+L+ +A RR+ Y+E +R + +
Sbjct: 115 SERLEQALRLEPGELETQEPRGLVRQSVELRRQLQEEQASYRRKLQAYQEGQQR-QAQLV 173
Query: 168 EMYKLSSEQFHEAASKMESTIKPRRVEPVCSGLQAQILHCYRDRPHEVLLCSDLVK 223
+ + Q+ + S++E + R E L+ Q L RD H L S L++
Sbjct: 174 QRLQGKILQYKKRCSELEQQLLERSGE-----LEQQRL---RDTEHSQDLESALIR 221
Score = 28.1 bits (61), Expect = 6.8
Identities = 22/95 (23%), Positives = 45/95 (47%), Gaps = 10/95 (10%)
Query: 92 QEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRLARELESREAELRRR 151
+E A ++ Q +RE+EAA + +A + + E+++ L LE+ + EL
Sbjct: 985 REQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEE---LLARLEAEKEEL--- 1038
Query: 152 DTFYKEQLERIERKNAEMYKLSSEQFHEAASKMES 186
E++ ++++ E L+ + +A S ES
Sbjct: 1039 ----SEEIAALQQERDEGLLLAESEKQQALSLKES 1069
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 36.2 bits (82), Expect = 0.025
Identities = 29/108 (26%), Positives = 46/108 (42%), Gaps = 19/108 (17%)
Query: 88 KRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRLARELESREAE 147
KR E++HA +++K +RE E +H EEQ R E + R
Sbjct: 104 KRKEKKHARVKEK-----EREHERRKRH-------------REEQDKARREWERQKRREM 145
Query: 148 LRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASK-MESTIKPRRVE 194
R +++LE++ERK K+ +Q + K E + RR E
Sbjct: 146 AREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKE 193
Score = 28.9 bits (63), Expect = 4.0
Identities = 32/153 (20%), Positives = 52/153 (33%), Gaps = 26/153 (16%)
Query: 42 SSPPPAPTSSTFGLQDGNLRAPHKESTLPR-------------------SGSSGGQQPSG 82
S PP P F L DG R P KE + + SS + SG
Sbjct: 221 SRSPPRPPRERFELGDG--RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG 278
Query: 83 MKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRLARELE 142
+E E+E +++ ++ E + + TG S EQ + ++ E
Sbjct: 279 SEE-----EEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 333
Query: 143 SREAELRRRDTFYKEQLERIERKNAEMYKLSSE 175
S + E + R +R + E + E
Sbjct: 334 SEDEERENENHLLVVPESRFDRDSGESEEAEEE 366
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 36.2 bits (82), Expect = 0.025
Identities = 29/108 (26%), Positives = 46/108 (42%), Gaps = 19/108 (17%)
Query: 88 KRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRLARELESREAE 147
KR E++HA +++K +RE E +H EEQ R E + R
Sbjct: 70 KRKEKKHARVKEK-----EREHERRKRH-------------REEQDKARREWERQKRREM 111
Query: 148 LRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASK-MESTIKPRRVE 194
R +++LE++ERK K+ +Q + K E + RR E
Sbjct: 112 AREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKE 159
Score = 28.9 bits (63), Expect = 4.0
Identities = 32/153 (20%), Positives = 52/153 (33%), Gaps = 26/153 (16%)
Query: 42 SSPPPAPTSSTFGLQDGNLRAPHKESTLPR-------------------SGSSGGQQPSG 82
S PP P F L DG R P KE + + SS + SG
Sbjct: 187 SRSPPRPPRERFELGDG--RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG 244
Query: 83 MKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRLARELE 142
+E E+E +++ ++ E + + TG S EQ + ++ E
Sbjct: 245 SEE-----EEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 299
Query: 143 SREAELRRRDTFYKEQLERIERKNAEMYKLSSE 175
S + E + R +R + E + E
Sbjct: 300 SEDEERENENHLLVVPESRFDRDSGESEEAEEE 332
>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
sapiens]
Length = 693
Score = 36.2 bits (82), Expect = 0.025
Identities = 45/200 (22%), Positives = 78/200 (39%), Gaps = 28/200 (14%)
Query: 18 EEERVRVLQGVRLSENVVNRMKE-----PSSPPPAPTSSTFGLQD-------------GN 59
+EE+ R + ++ E ++ +K PS PPA TS LQD G
Sbjct: 258 KEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGK 317
Query: 60 LRAP-HKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKA 118
L++ L Q+ +E ++ E + Q++L + +R RE K
Sbjct: 318 LQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLRE----QQKT 373
Query: 119 SLPTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFH 178
GE + +EQ+ + L E L++++ +Q ER+ +K + K Q
Sbjct: 374 LQEQGE-RLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQK----QEE 428
Query: 179 EAASKMESTIKPRRVEPVCS 198
A + + EP CS
Sbjct: 429 RLALSQNHKLDKQLAEPQCS 448
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 35.8 bits (81), Expect = 0.033
Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 79 QPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRLA 138
Q + ++E + R E+E + K+ R++E + L EG + +E+K R
Sbjct: 266 QTNTLQEEMWRQEEELREQEKKI-----RKQEEKMWRQEERLREQEGKMREQEEKMWRQE 320
Query: 139 RELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKM 184
+ L +E ELR ++ +EQ E R+ E + E+ E KM
Sbjct: 321 KRLREQEKELREQEKELREQKEL--REQEEQMQEQEEKMWEQEEKM 364
Score = 33.1 bits (74), Expect = 0.21
Identities = 23/112 (20%), Positives = 50/112 (44%), Gaps = 9/112 (8%)
Query: 83 MKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRLARELE 142
M+E K EQE +K+++ K E++ + K T + EE+ +++
Sbjct: 673 MQEQEKMQEQE-----EKIWEQEKMEKKTQEQEKK----TWDQEKMREEESMREREKKMR 723
Query: 143 SREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMESTIKPRRVE 194
E +R ++ +EQ E+++ + EM++ + + + E P + E
Sbjct: 724 EEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKE 775
Score = 29.6 bits (65), Expect = 2.3
Identities = 23/114 (20%), Positives = 50/114 (43%), Gaps = 4/114 (3%)
Query: 78 QQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRL 137
+Q ++E K ++ +++ Q RE+E + + + E + +E+K R
Sbjct: 318 RQEKRLREQEKELREQEKELRE---QKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQ 374
Query: 138 ARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMESTIKPR 191
L +E ++R ++ ++Q ER+ ++ E + E+ E E K R
Sbjct: 375 EERLWEQEKQMREQEQKMRDQEERMWEQD-ERLREKEERMREQEKMWEQVEKMR 427
Score = 29.6 bits (65), Expect = 2.3
Identities = 15/91 (16%), Positives = 43/91 (47%), Gaps = 7/91 (7%)
Query: 89 RYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRLARELESREAEL 148
R ++E Q+K+++ ++ RE + + EE++ + RE ++
Sbjct: 407 REKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEER-------IREREKKM 459
Query: 149 RRRDTFYKEQLERIERKNAEMYKLSSEQFHE 179
R + +EQ E+++++ M++ +++ +
Sbjct: 460 REEEETMREQEEKMQKQEENMWEQEEKEWQQ 490
Score = 28.1 bits (61), Expect = 6.8
Identities = 23/111 (20%), Positives = 48/111 (43%), Gaps = 19/111 (17%)
Query: 84 KEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRLARELES 143
+EG R ++E K+++ KR RE + E++K +R +EL
Sbjct: 305 QEGKMREQEE------KMWRQEKRLREQEKE-------------LREQEKELREQKELRE 345
Query: 144 REAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMESTIKPRRVE 194
+E +++ ++ EQ E++ + +M++ + + E K R E
Sbjct: 346 QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE 396
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.126 0.348
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,232,841
Number of Sequences: 37866
Number of extensions: 443077
Number of successful extensions: 3331
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 297
Number of HSP's that attempted gapping in prelim test: 2711
Number of HSP's gapped (non-prelim): 809
length of query: 235
length of database: 18,247,518
effective HSP length: 99
effective length of query: 136
effective length of database: 14,498,784
effective search space: 1971834624
effective search space used: 1971834624
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.