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Search of human proteins with 8922077
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]
(739 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens] 1484 0.0
gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo s... 720 0.0
gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo s... 702 0.0
gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo... 684 0.0
gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo s... 666 0.0
gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa... 257 2e-68
gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sa... 257 2e-68
gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo sa... 250 4e-66
gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sa... 250 4e-66
gi|226530771 adenosine deaminase domain containing 1 (testis-spe... 158 2e-38
gi|21245124 adenosine deaminase domain containing 1 (testis-spec... 158 2e-38
gi|226529650 adenosine deaminase domain containing 1 (testis-spe... 143 5e-34
gi|223972690 adenosine deaminase domain containing 2 isoform 2 [... 135 2e-31
gi|223972688 adenosine deaminase domain containing 2 isoform 1 [... 130 4e-30
gi|24234756 interleukin enhancer binding factor 3 isoform c [Hom... 129 1e-29
gi|24234753 interleukin enhancer binding factor 3 isoform b [Hom... 129 1e-29
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 129 1e-29
gi|212549555 interleukin enhancer binding factor 3 isoform e [Ho... 128 2e-29
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 128 2e-29
gi|21361745 spermatid perinuclear RNA binding protein [Homo sapi... 121 3e-27
gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens] 73 8e-13
gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens] 50 1e-05
gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens] 50 1e-05
gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens] 50 1e-05
gi|7657625 staufen homolog 2 [Homo sapiens] 49 1e-05
gi|82659089 staufen isoform a [Homo sapiens] 44 7e-04
gi|82659087 staufen isoform b [Homo sapiens] 44 7e-04
gi|82659085 staufen isoform a [Homo sapiens] 44 7e-04
gi|82659083 staufen isoform a [Homo sapiens] 44 7e-04
gi|82659091 staufen isoform c [Homo sapiens] 42 0.002
>gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]
Length = 739
Score = 1484 bits (3843), Expect = 0.0
Identities = 739/739 (100%), Positives = 739/739 (100%)
Query: 1 MASVLGSGRGSGGLSSQLKCKSKRRRRRRSKRKDKVSILSTFLAPFKHLSPGITNTEDDD 60
MASVLGSGRGSGGLSSQLKCKSKRRRRRRSKRKDKVSILSTFLAPFKHLSPGITNTEDDD
Sbjct: 1 MASVLGSGRGSGGLSSQLKCKSKRRRRRRSKRKDKVSILSTFLAPFKHLSPGITNTEDDD 60
Query: 61 TLSTSSAEVKENRNVGNLAARPPPSGDRARGGAPGAKRKRPLEEGNGGHLCKLQLVWKKL 120
TLSTSSAEVKENRNVGNLAARPPPSGDRARGGAPGAKRKRPLEEGNGGHLCKLQLVWKKL
Sbjct: 61 TLSTSSAEVKENRNVGNLAARPPPSGDRARGGAPGAKRKRPLEEGNGGHLCKLQLVWKKL 120
Query: 121 SWSVAPKNALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMR 180
SWSVAPKNALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMR
Sbjct: 121 SWSVAPKNALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMR 180
Query: 181 AAELALRSFVQFPNACQAHLAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGR 240
AAELALRSFVQFPNACQAHLAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGR
Sbjct: 181 AAELALRSFVQFPNACQAHLAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGR 240
Query: 241 PGDAALLSAAYGRRRLLCRALDLVGPTPATPAAPGERNPVVLLNRLRAGLRYVCLAEPAE 300
PGDAALLSAAYGRRRLLCRALDLVGPTPATPAAPGERNPVVLLNRLRAGLRYVCLAEPAE
Sbjct: 241 PGDAALLSAAYGRRRLLCRALDLVGPTPATPAAPGERNPVVLLNRLRAGLRYVCLAEPAE 300
Query: 301 RRARSFVMAVSVDGRTFEGSGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMPQE 360
RRARSFVMAVSVDGRTFEGSGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMPQE
Sbjct: 301 RRARSFVMAVSVDGRTFEGSGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMPQE 360
Query: 361 FADSISQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDARQAQVVALSSGTKCISGEH 420
FADSISQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDARQAQVVALSSGTKCISGEH
Sbjct: 361 FADSISQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDARQAQVVALSSGTKCISGEH 420
Query: 421 LSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSERSIFVRLKEGGYRLRENIL 480
LSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSERSIFVRLKEGGYRLRENIL
Sbjct: 421 LSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSERSIFVRLKEGGYRLRENIL 480
Query: 481 FHLYVSTSPCGDARLHSPYEITTDLHSSKHLVRKFRGHLRTKIESGEGTVPVRGPSAVQT 540
FHLYVSTSPCGDARLHSPYEITTDLHSSKHLVRKFRGHLRTKIESGEGTVPVRGPSAVQT
Sbjct: 481 FHLYVSTSPCGDARLHSPYEITTDLHSSKHLVRKFRGHLRTKIESGEGTVPVRGPSAVQT 540
Query: 541 WDGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEPVYLQSIVVGSLHHTGHLARVMS 600
WDGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEPVYLQSIVVGSLHHTGHLARVMS
Sbjct: 541 WDGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEPVYLQSIVVGSLHHTGHLARVMS 600
Query: 601 HRMEGVGQLPASYRHNRPLLSGVSDAEARQPGKSPPFSMNWVVGSADLEIINATTGRRSC 660
HRMEGVGQLPASYRHNRPLLSGVSDAEARQPGKSPPFSMNWVVGSADLEIINATTGRRSC
Sbjct: 601 HRMEGVGQLPASYRHNRPLLSGVSDAEARQPGKSPPFSMNWVVGSADLEIINATTGRRSC 660
Query: 661 GGPSRLCKHVLSARWARLYGRLSTRTPSPGDTPSMYCEAKLGAHTYQSVKQQLFKAFQKA 720
GGPSRLCKHVLSARWARLYGRLSTRTPSPGDTPSMYCEAKLGAHTYQSVKQQLFKAFQKA
Sbjct: 661 GGPSRLCKHVLSARWARLYGRLSTRTPSPGDTPSMYCEAKLGAHTYQSVKQQLFKAFQKA 720
Query: 721 GLGTWVRKPPEQQQFLLTL 739
GLGTWVRKPPEQQQFLLTL
Sbjct: 721 GLGTWVRKPPEQQQFLLTL 739
>gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo
sapiens]
Length = 701
Score = 720 bits (1859), Expect = 0.0
Identities = 374/698 (53%), Positives = 489/698 (70%), Gaps = 17/698 (2%)
Query: 57 EDDDTLSTSSAEVKENRNVGNLAAR------PPPSGDRARGGAPGAKRKRPLEEGNGGHL 110
ED++ +S+SS +VKENRN+ N++ + P + GG G RKRPLEEG+ GH
Sbjct: 4 EDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSNGHS 63
Query: 111 CKLQLVWKKLSWSVAPKNALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGT 170
+K V PKNAL+QL+E++PGLQY +SQTGPVHAP+F ++VEVNG FEG+
Sbjct: 64 KYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEGS 123
Query: 171 GPTKKKAKMRAAELALRSFVQFPNACQAHLAMGGGPGPGTDFTSDQADFPDTLFQEFEPP 230
GPTKKKAK+ AAE ALRSFVQFPNA +AHLAMG TDFTSDQADFPDTLF FE P
Sbjct: 124 GPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETP 183
Query: 231 --APRPGLAGGRPGDAALLSAAYGRRRLLCRALDLVGPTPATPA--APGERNPVVLLNRL 286
A P G D+ S A P P P P +NPV++LN L
Sbjct: 184 DKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMILNEL 243
Query: 287 RAGLRYVCLAEPAERRARSFVMAVSVDGRTFEGSGRSKKLARGQAAQAALQELFDI---Q 343
R GL+Y L+E E A+SFVM+V VDG+ FEGSGR+KKLA+ +AAQ+AL +F++ Q
Sbjct: 244 RPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQ 303
Query: 344 MPGHAP--GRARRTPMPQEFADSISQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDA 401
P P + +PQ AD++S+LV KF ++T + + HAR K LAG+VMT G D
Sbjct: 304 TPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDV 363
Query: 402 RQAQVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSE 461
+ A+V+++S+GTKCI+GE++SD+GL +NDCHAE+++RR+ L FLYTQLEL+L+ + +D +
Sbjct: 364 KDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNK-DDQK 422
Query: 462 RSIFVRLKEGGYRLRENILFHLYVSTSPCGDARLHSPYEITTDLHSSKHLVRKFRGHLRT 521
RSIF + + GG+RL+EN+ FHLY+STSPCGDAR+ SP+E + + +H RK RG LRT
Sbjct: 423 RSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEEPADRHPNRKARGQLRT 482
Query: 522 KIESGEGTVPVRGPSAVQTWDGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEPVYL 581
KIESGEGT+PVR +++QTWDGVL GE+L+TMSC+DKIARWNV+G+QG+LLS FVEP+Y
Sbjct: 483 KIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYF 542
Query: 582 QSIVVGSLHHTGHLARVMSHRMEGVGQLPASYRHNRPLLSGVSDAEARQPGKSPPFSMNW 641
SI++GSL+H HL+R M R+ + LP Y N+PLLSG+S+AEARQPGK+P FS+NW
Sbjct: 543 SSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNW 602
Query: 642 VVGSADLEIINATTGRRSCGGPSRLCKHVLSARWARLYGRL-STRTPSPGDTPSMYCEAK 700
VG + +E+INATTG+ G SRLCKH L RW R++G++ S S P++Y E+K
Sbjct: 603 TVGDSAIEVINATTGKDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESK 662
Query: 701 LGAHTYQSVKQQLFKAFQKAGLGTWVRKPPEQQQFLLT 738
L A YQ+ K +LF AF KAGLG WV KP EQ QF LT
Sbjct: 663 LAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLT 700
>gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo
sapiens]
Length = 741
Score = 702 bits (1813), Expect = 0.0
Identities = 376/738 (50%), Positives = 492/738 (66%), Gaps = 57/738 (7%)
Query: 57 EDDDTLSTSSAEVKENRNVGNLAAR------PPPSGDRARGGAPGAKRKRPLEEGNGGHL 110
ED++ +S+SS +VKENRN+ N++ + P + GG G RKRPLEEG+ GH
Sbjct: 4 EDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSNGHS 63
Query: 111 CKLQLVWKKLSWSVAPKNALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGT 170
+K V PKNAL+QL+E++PGLQY +SQTGPVHAP+F ++VEVNG FEG+
Sbjct: 64 KYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEGS 123
Query: 171 GPTKKKAKMRAAELALRSFVQFPNACQAHLAMGGGPGPGTDFTSDQADFPDTLFQEFEPP 230
GPTKKKAK+ AAE ALRSFVQFPNA +AHLAMG TDFTSDQADFPDTLF FE P
Sbjct: 124 GPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETP 183
Query: 231 --APRPGLAGGRPGDAALLSAAYGRRRLLCRALDLVGPTPATP--AAPGERNPVVLLNRL 286
A P G D+ S A P P P P +NPV++LN L
Sbjct: 184 DKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMILNEL 243
Query: 287 RAGLRYVCLAEPAERRARSFVMAVSVDGRTFEGSGRSKKLARGQAAQAALQELFDI---Q 343
R GL+Y L+E E A+SFVM+V VDG+ FEGSGR+KKLA+ +AAQ+AL +F++ Q
Sbjct: 244 RPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQ 303
Query: 344 MPGH--APGRARRTPMPQEFADSISQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDA 401
P P + +PQ AD++S+LV KF ++T + + HAR K LAG+VMT G D
Sbjct: 304 TPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDV 363
Query: 402 RQAQVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSE 461
+ A+V+++S+GTKCI+GE++SD+GL +NDCHAE+++RR+ L FLYTQLEL+L+ ++D +
Sbjct: 364 KDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLN-NKDDQK 422
Query: 462 RSIFVRLKEGGYRLRENILFHLYVSTSPCGDARLHSPYE--------------------- 500
RSIF + + GG+RL+EN+ FHLY+STSPCGDAR+ SP+E
Sbjct: 423 RSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGS 482
Query: 501 -------ITTDLHSS------------KHLVRKFRGHLRTKIESGEGTVPVRGPSAVQTW 541
+ +D +S +H RK RG LRTKIESGEGT+PVR +++QTW
Sbjct: 483 LQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTW 542
Query: 542 DGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEPVYLQSIVVGSLHHTGHLARVMSH 601
DGVL GE+L+TMSC+DKIARWNV+G+QG+LLS FVEP+Y SI++GSL+H HL+R M
Sbjct: 543 DGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQ 602
Query: 602 RMEGVGQLPASYRHNRPLLSGVSDAEARQPGKSPPFSMNWVVGSADLEIINATTGRRSCG 661
R+ + LP Y N+PLLSG+S+AEARQPGK+P FS+NW VG + +E+INATTG+ G
Sbjct: 603 RISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDELG 662
Query: 662 GPSRLCKHVLSARWARLYGRL-STRTPSPGDTPSMYCEAKLGAHTYQSVKQQLFKAFQKA 720
SRLCKH L RW R++G++ S S P++Y E+KL A YQ+ K +LF AF KA
Sbjct: 663 RASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKA 722
Query: 721 GLGTWVRKPPEQQQFLLT 738
GLG WV KP EQ QF LT
Sbjct: 723 GLGAWVEKPTEQDQFSLT 740
>gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo
sapiens]
Length = 674
Score = 684 bits (1764), Expect = 0.0
Identities = 355/670 (52%), Positives = 469/670 (70%), Gaps = 17/670 (2%)
Query: 57 EDDDTLSTSSAEVKENRNVGNLAAR------PPPSGDRARGGAPGAKRKRPLEEGNGGHL 110
ED++ +S+SS +VKENRN+ N++ + P + GG G RKRPLEEG+ GH
Sbjct: 4 EDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSNGHS 63
Query: 111 CKLQLVWKKLSWSVAPKNALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGT 170
+K V PKNAL+QL+E++PGLQY +SQTGPVHAP+F ++VEVNG FEG+
Sbjct: 64 KYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEGS 123
Query: 171 GPTKKKAKMRAAELALRSFVQFPNACQAHLAMGGGPGPGTDFTSDQADFPDTLFQEFEPP 230
GPTKKKAK+ AAE ALRSFVQFPNA +AHLAMG TDFTSDQADFPDTLF FE P
Sbjct: 124 GPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETP 183
Query: 231 --APRPGLAGGRPGDAALLSAAYGRRRLLCRALDLVGPTPATPA--APGERNPVVLLNRL 286
A P G D+ S A P P P P +NPV++LN L
Sbjct: 184 DKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMILNEL 243
Query: 287 RAGLRYVCLAEPAERRARSFVMAVSVDGRTFEGSGRSKKLARGQAAQAALQELFDI---Q 343
R GL+Y L+E E A+SFVM+V VDG+ FEGSGR+KKLA+ +AAQ+AL +F++ Q
Sbjct: 244 RPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQ 303
Query: 344 MPGHAP--GRARRTPMPQEFADSISQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDA 401
P P + +PQ AD++S+LV KF ++T + + HAR K LAG+VMT G D
Sbjct: 304 TPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDV 363
Query: 402 RQAQVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSE 461
+ A+V+++S+GTKCI+GE++SD+GL +NDCHAE+++RR+ L FLYTQLEL+L+ + +D +
Sbjct: 364 KDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNK-DDQK 422
Query: 462 RSIFVRLKEGGYRLRENILFHLYVSTSPCGDARLHSPYEITTDLHSSKHLVRKFRGHLRT 521
RSIF + + GG+RL+EN+ FHLY+STSPCGDAR+ SP+E + + +H RK RG LRT
Sbjct: 423 RSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEEPADRHPNRKARGQLRT 482
Query: 522 KIESGEGTVPVRGPSAVQTWDGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEPVYL 581
KIESGEGT+PVR +++QTWDGVL GE+L+TMSC+DKIARWNV+G+QG+LLS FVEP+Y
Sbjct: 483 KIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYF 542
Query: 582 QSIVVGSLHHTGHLARVMSHRMEGVGQLPASYRHNRPLLSGVSDAEARQPGKSPPFSMNW 641
SI++GSL+H HL+R M R+ + LP Y N+PLLSG+S+AEARQPGK+P FS+NW
Sbjct: 543 SSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNW 602
Query: 642 VVGSADLEIINATTGRRSCGGPSRLCKHVLSARWARLYGRL-STRTPSPGDTPSMYCEAK 700
VG + +E+INATTG+ G SRLCKH L RW R++G++ S S P++Y E+K
Sbjct: 603 TVGDSAIEVINATTGKDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESK 662
Query: 701 LGAHTYQSVK 710
L A YQ+ K
Sbjct: 663 LAAKEYQAAK 672
>gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo
sapiens]
Length = 714
Score = 666 bits (1718), Expect = 0.0
Identities = 357/710 (50%), Positives = 472/710 (66%), Gaps = 57/710 (8%)
Query: 57 EDDDTLSTSSAEVKENRNVGNLAAR------PPPSGDRARGGAPGAKRKRPLEEGNGGHL 110
ED++ +S+SS +VKENRN+ N++ + P + GG G RKRPLEEG+ GH
Sbjct: 4 EDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSNGHS 63
Query: 111 CKLQLVWKKLSWSVAPKNALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGT 170
+K V PKNAL+QL+E++PGLQY +SQTGPVHAP+F ++VEVNG FEG+
Sbjct: 64 KYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEGS 123
Query: 171 GPTKKKAKMRAAELALRSFVQFPNACQAHLAMGGGPGPGTDFTSDQADFPDTLFQEFEPP 230
GPTKKKAK+ AAE ALRSFVQFPNA +AHLAMG TDFTSDQADFPDTLF FE P
Sbjct: 124 GPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETP 183
Query: 231 --APRPGLAGGRPGDAALLSAAYGRRRLLCRALDLVGPTPATP--AAPGERNPVVLLNRL 286
A P G D+ S A P P P P +NPV++LN L
Sbjct: 184 DKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMILNEL 243
Query: 287 RAGLRYVCLAEPAERRARSFVMAVSVDGRTFEGSGRSKKLARGQAAQAALQELFDI---Q 343
R GL+Y L+E E A+SFVM+V VDG+ FEGSGR+KKLA+ +AAQ+AL +F++ Q
Sbjct: 244 RPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQ 303
Query: 344 MPGH--APGRARRTPMPQEFADSISQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDA 401
P P + +PQ AD++S+LV KF ++T + + HAR K LAG+VMT G D
Sbjct: 304 TPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDV 363
Query: 402 RQAQVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSE 461
+ A+V+++S+GTKCI+GE++SD+GL +NDCHAE+++RR+ L FLYTQLEL+L+ ++D +
Sbjct: 364 KDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLN-NKDDQK 422
Query: 462 RSIFVRLKEGGYRLRENILFHLYVSTSPCGDARLHSPYE--------------------- 500
RSIF + + GG+RL+EN+ FHLY+STSPCGDAR+ SP+E
Sbjct: 423 RSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGS 482
Query: 501 -------ITTDLHSS------------KHLVRKFRGHLRTKIESGEGTVPVRGPSAVQTW 541
+ +D +S +H RK RG LRTKIESGEGT+PVR +++QTW
Sbjct: 483 LQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTW 542
Query: 542 DGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEPVYLQSIVVGSLHHTGHLARVMSH 601
DGVL GE+L+TMSC+DKIARWNV+G+QG+LLS FVEP+Y SI++GSL+H HL+R M
Sbjct: 543 DGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQ 602
Query: 602 RMEGVGQLPASYRHNRPLLSGVSDAEARQPGKSPPFSMNWVVGSADLEIINATTGRRSCG 661
R+ + LP Y N+PLLSG+S+AEARQPGK+P FS+NW VG + +E+INATTG+ G
Sbjct: 603 RISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDELG 662
Query: 662 GPSRLCKHVLSARWARLYGRL-STRTPSPGDTPSMYCEAKLGAHTYQSVK 710
SRLCKH L RW R++G++ S S P++Y E+KL A YQ+ K
Sbjct: 663 RASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 712
>gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
sapiens]
Length = 1181
Score = 257 bits (657), Expect = 2e-68
Identities = 167/446 (37%), Positives = 234/446 (52%), Gaps = 20/446 (4%)
Query: 306 FVMAVSVDGRTFEG-SGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMPQEFADS 364
FV V GR F SKK + +AA AAL+ L G F D
Sbjct: 739 FVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTELPLTGSTFHDQ 798
Query: 365 ISQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDARQAQVVALSSGTKCISGEHLSDQ 424
I+ L + F +T P K LA I+M K + VV+L +G +C+ G+ LS +
Sbjct: 799 IAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSED-MGVVVSLGTGNRCVKGDSLSLK 857
Query: 425 GLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSERSIFVRLKEGG-YRLRENILFHL 483
G VNDCHAE+++RR F+ FLY++L + S+ +DS IF K G ++++ + FHL
Sbjct: 858 GETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDS---IFEPAKGGEKLQIKKTVSFHL 914
Query: 484 YVSTSPCGDARLH--SPYEITTDLHSSKH---LVRKFRGHLRTKIESGEGTVPVRGPSAV 538
Y+ST+PCGD L S + + S+H +G LRTK+E+GEGT+PV V
Sbjct: 915 YISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIV 974
Query: 539 QTWDGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEPVYLQSIVVGSLHHTGHLARV 598
TWDG+ LGE+L TMSC+DKI RWNVLGLQGALL+HF++P+YL+S+ +G L GHL R
Sbjct: 975 PTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRA 1034
Query: 599 MSHRMEGVGQ-LPASYRH----NRPLLSGVSDAEA-RQPGKSPPFSMNWVVGSA-DLEII 651
+ R+ G RH N P + VS ++ RQ GK+ S+NW + DLEI+
Sbjct: 1035 ICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEIL 1094
Query: 652 NATTGRRSCGGPSRLCKHVLSARWARLYGRLSTRTPSPGDTPSMYCEAKLGAHTYQSVKQ 711
+ T G + GP V L+ +L + Y EAK A Y++ K
Sbjct: 1095 DGTRG--TVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKN 1152
Query: 712 QLFKAFQKAGLGTWVRKPPEQQQFLL 737
K + G G W+ KP E++ F L
Sbjct: 1153 YFKKGLKDMGYGNWISKPQEEKNFYL 1178
Score = 43.5 bits (101), Expect = 7e-04
Identities = 24/66 (36%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
Query: 125 APKNALVQ-LHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEG-TGPTKKKAKMRAA 182
+P L++ +H+L ++R +S+ GP H P F V V TF + P+KK AK AA
Sbjct: 614 SPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAA 673
Query: 183 ELALRS 188
E A+++
Sbjct: 674 EEAMKA 679
Score = 35.8 bits (81), Expect = 0.15
Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTFEGT-GPTKKKAKMRAAELALRSFV 190
+++ V Q+GP H P F +V G F +KK+ K AA+ ALR +
Sbjct: 724 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 774
Score = 32.0 bits (71), Expect = 2.1
Identities = 44/205 (21%), Positives = 74/205 (36%), Gaps = 50/205 (24%)
Query: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTF-EGTGPTKKKAKMRAAELALRSFVQFPNACQAH 199
++ + Q+GP H P F V +NG F +KK AK AA A+
Sbjct: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAM------------- 566
Query: 200 LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCR 259
L +E A + + S+ Y + +
Sbjct: 567 ---------------------TILLEE----------AKAKDSGKSEESSHYSTEKESEK 595
Query: 260 ALDLVGPTPATPAAPGERNPVVLL----NRLRAGLRYVCLAEPAERRARSFVMAVSVDGR 315
+ PTP+ + ++PV L ++L + L++ F V+V +
Sbjct: 596 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 655
Query: 316 TFEG-SGRSKKLARGQAAQAALQEL 339
TF S SKK+A+ AA+ A++ L
Sbjct: 656 TFPSVSAPSKKVAKQMAAEEAMKAL 680
>gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo
sapiens]
Length = 1200
Score = 257 bits (657), Expect = 2e-68
Identities = 167/446 (37%), Positives = 234/446 (52%), Gaps = 20/446 (4%)
Query: 306 FVMAVSVDGRTFEG-SGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMPQEFADS 364
FV V GR F SKK + +AA AAL+ L G F D
Sbjct: 758 FVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTELPLTGSTFHDQ 817
Query: 365 ISQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDARQAQVVALSSGTKCISGEHLSDQ 424
I+ L + F +T P K LA I+M K + VV+L +G +C+ G+ LS +
Sbjct: 818 IAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSED-MGVVVSLGTGNRCVKGDSLSLK 876
Query: 425 GLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSERSIFVRLKEGG-YRLRENILFHL 483
G VNDCHAE+++RR F+ FLY++L + S+ +DS IF K G ++++ + FHL
Sbjct: 877 GETVNDCHAEIISRRGFIRFLYSELMKYNSQTAKDS---IFEPAKGGEKLQIKKTVSFHL 933
Query: 484 YVSTSPCGDARLH--SPYEITTDLHSSKH---LVRKFRGHLRTKIESGEGTVPVRGPSAV 538
Y+ST+PCGD L S + + S+H +G LRTK+E+GEGT+PV V
Sbjct: 934 YISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIV 993
Query: 539 QTWDGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEPVYLQSIVVGSLHHTGHLARV 598
TWDG+ LGE+L TMSC+DKI RWNVLGLQGALL+HF++P+YL+S+ +G L GHL R
Sbjct: 994 PTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRA 1053
Query: 599 MSHRMEGVGQ-LPASYRH----NRPLLSGVSDAEA-RQPGKSPPFSMNWVVGSA-DLEII 651
+ R+ G RH N P + VS ++ RQ GK+ S+NW + DLEI+
Sbjct: 1054 ICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEIL 1113
Query: 652 NATTGRRSCGGPSRLCKHVLSARWARLYGRLSTRTPSPGDTPSMYCEAKLGAHTYQSVKQ 711
+ T G + GP V L+ +L + Y EAK A Y++ K
Sbjct: 1114 DGTRG--TVDGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKN 1171
Query: 712 QLFKAFQKAGLGTWVRKPPEQQQFLL 737
K + G G W+ KP E++ F L
Sbjct: 1172 YFKKGLKDMGYGNWISKPQEEKNFYL 1197
Score = 43.5 bits (101), Expect = 7e-04
Identities = 24/66 (36%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
Query: 125 APKNALVQ-LHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEG-TGPTKKKAKMRAA 182
+P L++ +H+L ++R +S+ GP H P F V V TF + P+KK AK AA
Sbjct: 614 SPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAA 673
Query: 183 ELALRS 188
E A+++
Sbjct: 674 EEAMKA 679
Score = 35.8 bits (81), Expect = 0.15
Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTFEGT-GPTKKKAKMRAAELALRSFV 190
+++ V Q+GP H P F +V G F +KK+ K AA+ ALR +
Sbjct: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 793
Score = 33.9 bits (76), Expect = 0.56
Identities = 51/246 (20%), Positives = 88/246 (35%), Gaps = 59/246 (23%)
Query: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTF-EGTGPTKKKAKMRAAELALRSFVQFPNACQAH 199
++ + Q+GP H P F V +NG F +KK AK AA A+
Sbjct: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAM------------- 566
Query: 200 LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCR 259
L +E A + + S+ Y + +
Sbjct: 567 ---------------------TILLEE----------AKAKDSGKSEESSHYSTEKESEK 595
Query: 260 ALDLVGPTPATPAAPGERNPVVLL----NRLRAGLRYVCLAEPAERRARSFVMAVSVDGR 315
+ PTP+ + ++PV L ++L + L++ F V+V +
Sbjct: 596 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 655
Query: 316 TFEG-SGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMPQ----EFADSISQLVT 370
TF S SKK+A+ AA+ A++ L G A P+ E D++ ++
Sbjct: 656 TFPSVSAPSKKVAKQMAAEEAMKALH-----GEATNSMASDNQPEGMISESLDNLESMMP 710
Query: 371 QKFREV 376
K R++
Sbjct: 711 NKVRKI 716
>gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo
sapiens]
Length = 931
Score = 250 bits (638), Expect = 4e-66
Identities = 169/472 (35%), Positives = 237/472 (50%), Gaps = 46/472 (9%)
Query: 306 FVMAVSVDGRTFEG-SGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMP------ 358
FV V GR F SKK + +AA AAL+ L G TP+
Sbjct: 463 FVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRR 522
Query: 359 --------------------QEFADSISQLVTQKFREVTTDLTPMHARHKALAGIVMTKG 398
F D I+ L + F +T P K LA I+M K
Sbjct: 523 TMLLLSRSPEAQPKTLPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKD 582
Query: 399 LDARQAQVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRRE 458
+ VV+L +G +C+ G+ LS +G VNDCHAE+++RR F+ FLY++L + S+ +
Sbjct: 583 SED-MGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAK 641
Query: 459 DSERSIFVRLKEGG-YRLRENILFHLYVSTSPCGDARLH--SPYEITTDLHSSKH---LV 512
DS IF K G ++++ + FHLY+ST+PCGD L S + + S+H
Sbjct: 642 DS---IFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFE 698
Query: 513 RKFRGHLRTKIESGEGTVPVRGPSAVQTWDGVLLGEQLITMSCTDKIARWNVLGLQGALL 572
+G LRTK+E+GEGT+PV V TWDG+ LGE+L TMSC+DKI RWNVLGLQGALL
Sbjct: 699 NPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALL 758
Query: 573 SHFVEPVYLQSIVVGSLHHTGHLARVMSHRMEGVGQ-LPASYRH----NRPLLSGVSDAE 627
+HF++P+YL+S+ +G L GHL R + R+ G RH N P + VS +
Sbjct: 759 THFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYD 818
Query: 628 A-RQPGKSPPFSMNWVVGSA-DLEIINATTGRRSCGGPSRLCKHVLSARWARLYGRLSTR 685
+ RQ GK+ S+NW + DLEI++ T G + GP V L+ +L +
Sbjct: 819 SKRQSGKTKETSVNWCLADGYDLEILDGTRG--TVDGPRNELSRVSKKNIFLLFKKLCSF 876
Query: 686 TPSPGDTPSMYCEAKLGAHTYQSVKQQLFKAFQKAGLGTWVRKPPEQQQFLL 737
Y EAK A Y++ K K + G G W+ KP E++ F L
Sbjct: 877 RYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYL 928
Score = 43.5 bits (101), Expect = 7e-04
Identities = 24/66 (36%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
Query: 125 APKNALVQ-LHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEG-TGPTKKKAKMRAA 182
+P L++ +H+L ++R +S+ GP H P F V V TF + P+KK AK AA
Sbjct: 319 SPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAA 378
Query: 183 ELALRS 188
E A+++
Sbjct: 379 EEAMKA 384
Score = 35.8 bits (81), Expect = 0.15
Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTFEGT-GPTKKKAKMRAAELALRSFV 190
+++ V Q+GP H P F +V G F +KK+ K AA+ ALR +
Sbjct: 448 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 498
Score = 33.9 bits (76), Expect = 0.56
Identities = 51/246 (20%), Positives = 88/246 (35%), Gaps = 59/246 (23%)
Query: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTF-EGTGPTKKKAKMRAAELALRSFVQFPNACQAH 199
++ + Q+GP H P F V +NG F +KK AK AA A+
Sbjct: 225 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAM------------- 271
Query: 200 LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCR 259
L +E A + + S+ Y + +
Sbjct: 272 ---------------------TILLEE----------AKAKDSGKSEESSHYSTEKESEK 300
Query: 260 ALDLVGPTPATPAAPGERNPVVLL----NRLRAGLRYVCLAEPAERRARSFVMAVSVDGR 315
+ PTP+ + ++PV L ++L + L++ F V+V +
Sbjct: 301 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 360
Query: 316 TFEG-SGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMPQ----EFADSISQLVT 370
TF S SKK+A+ AA+ A++ L G A P+ E D++ ++
Sbjct: 361 TFPSVSAPSKKVAKQMAAEEAMKALH-----GEATNSMASDNQPEGMISESLDNLESMMP 415
Query: 371 QKFREV 376
K R++
Sbjct: 416 NKVRKI 421
>gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo
sapiens]
Length = 1226
Score = 250 bits (638), Expect = 4e-66
Identities = 169/472 (35%), Positives = 237/472 (50%), Gaps = 46/472 (9%)
Query: 306 FVMAVSVDGRTFEG-SGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMP------ 358
FV V GR F SKK + +AA AAL+ L G TP+
Sbjct: 758 FVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERMGFTEVTPVTGASLRR 817
Query: 359 --------------------QEFADSISQLVTQKFREVTTDLTPMHARHKALAGIVMTKG 398
F D I+ L + F +T P K LA I+M K
Sbjct: 818 TMLLLSRSPEAQPKTLPLTGSTFHDQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKD 877
Query: 399 LDARQAQVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRRE 458
+ VV+L +G +C+ G+ LS +G VNDCHAE+++RR F+ FLY++L + S+ +
Sbjct: 878 SED-MGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKYNSQTAK 936
Query: 459 DSERSIFVRLKEGG-YRLRENILFHLYVSTSPCGDARLH--SPYEITTDLHSSKH---LV 512
DS IF K G ++++ + FHLY+ST+PCGD L S + + S+H
Sbjct: 937 DS---IFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESRHYPVFE 993
Query: 513 RKFRGHLRTKIESGEGTVPVRGPSAVQTWDGVLLGEQLITMSCTDKIARWNVLGLQGALL 572
+G LRTK+E+GEGT+PV V TWDG+ LGE+L TMSC+DKI RWNVLGLQGALL
Sbjct: 994 NPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALL 1053
Query: 573 SHFVEPVYLQSIVVGSLHHTGHLARVMSHRMEGVGQ-LPASYRH----NRPLLSGVSDAE 627
+HF++P+YL+S+ +G L GHL R + R+ G RH N P + VS +
Sbjct: 1054 THFLQPIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYD 1113
Query: 628 A-RQPGKSPPFSMNWVVGSA-DLEIINATTGRRSCGGPSRLCKHVLSARWARLYGRLSTR 685
+ RQ GK+ S+NW + DLEI++ T G + GP V L+ +L +
Sbjct: 1114 SKRQSGKTKETSVNWCLADGYDLEILDGTRG--TVDGPRNELSRVSKKNIFLLFKKLCSF 1171
Query: 686 TPSPGDTPSMYCEAKLGAHTYQSVKQQLFKAFQKAGLGTWVRKPPEQQQFLL 737
Y EAK A Y++ K K + G G W+ KP E++ F L
Sbjct: 1172 RYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYL 1223
Score = 43.5 bits (101), Expect = 7e-04
Identities = 24/66 (36%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
Query: 125 APKNALVQ-LHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEG-TGPTKKKAKMRAA 182
+P L++ +H+L ++R +S+ GP H P F V V TF + P+KK AK AA
Sbjct: 614 SPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAA 673
Query: 183 ELALRS 188
E A+++
Sbjct: 674 EEAMKA 679
Score = 35.8 bits (81), Expect = 0.15
Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTFEGT-GPTKKKAKMRAAELALRSFV 190
+++ V Q+GP H P F +V G F +KK+ K AA+ ALR +
Sbjct: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 793
Score = 33.9 bits (76), Expect = 0.56
Identities = 51/246 (20%), Positives = 88/246 (35%), Gaps = 59/246 (23%)
Query: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTF-EGTGPTKKKAKMRAAELALRSFVQFPNACQAH 199
++ + Q+GP H P F V +NG F +KK AK AA A+
Sbjct: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAM------------- 566
Query: 200 LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCR 259
L +E A + + S+ Y + +
Sbjct: 567 ---------------------TILLEE----------AKAKDSGKSEESSHYSTEKESEK 595
Query: 260 ALDLVGPTPATPAAPGERNPVVLL----NRLRAGLRYVCLAEPAERRARSFVMAVSVDGR 315
+ PTP+ + ++PV L ++L + L++ F V+V +
Sbjct: 596 TAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQ 655
Query: 316 TFEG-SGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMPQ----EFADSISQLVT 370
TF S SKK+A+ AA+ A++ L G A P+ E D++ ++
Sbjct: 656 TFPSVSAPSKKVAKQMAAEEAMKALH-----GEATNSMASDNQPEGMISESLDNLESMMP 710
Query: 371 QKFREV 376
K R++
Sbjct: 711 NKVRKI 716
>gi|226530771 adenosine deaminase domain containing 1
(testis-specific) isoform 3 [Homo sapiens]
Length = 558
Score = 158 bits (400), Expect = 2e-38
Identities = 141/470 (30%), Positives = 219/470 (46%), Gaps = 63/470 (13%)
Query: 306 FVMAVSVDGRTFE-GSGRSKKLARGQAAQAALQELFDIQMP--------GHAPGRARRTP 356
F VDG ++ G G++KK +R AA+ AL EL + P G P A
Sbjct: 110 FAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVV 169
Query: 357 MPQ--------------EFADSISQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDAR 402
+ + ++A ISQ+V ++F ++ ++ + +LA ++ + A
Sbjct: 170 LSELAYVSKVHYEGRHIQYA-KISQIVKERFNQLISNRSEYLKYSSSLAAFIIER---AG 225
Query: 403 QAQVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSER 462
Q +VVA+ +G S + + G V++D HA V ARR+ L + Y QL L SK E+
Sbjct: 226 QHEVVAIGTGEYNYS-QDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEK 284
Query: 463 SIFVRLKEGGY-RLRENILFHLYVSTSPCGDARLHSPYEITTDLHSSKHLVRKFRGHLRT 521
SIF L++NI LY++ P G A++ S L + H + F +
Sbjct: 285 SIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQIKS------QLRLNPHSISAFEANEEL 338
Query: 522 KIESGEGTVPVRGPSAVQTW---DGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEP 578
+ V V G + + DGV ++ +MS +DK+ RW VLG+QGALLSHF++P
Sbjct: 339 CLH-----VAVEGKIYLTVYCPKDGV---NRISSMSSSDKLTRWEVLGVQGALLSHFIQP 390
Query: 579 VYLQSIVV--GSLHHTGHLARVMSHRMEG--VGQLPASYRHNRPLLSGVSDAEARQPGKS 634
VY+ SI++ G+ T L + R++ +LP Y NRP +S V A Q
Sbjct: 391 VYISSILIGDGNCSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLE 450
Query: 635 PPF-SMNWVVGSADLEIINATTGRRSCGGP--------SRLCKHVLSARWARLYGRLSTR 685
F S+NW G LEI++ +G+ + P SRLCK + +R+ L
Sbjct: 451 YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKE 510
Query: 686 TPSPGDTPSMYCEAKLGAHTYQSVKQQLFKAFQKAGLGTWVRKPPEQQQF 735
G Y AK + +YQ K +L Q+ G G+W+ K P +QF
Sbjct: 511 LLEAG----TYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQF 556
Score = 38.9 bits (89), Expect = 0.017
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Query: 114 QLVWKKLSWSVAPKNALVQLHEL-RPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFE-GTG 171
+ + K + P +AL Q ++ R L + TG V P FA V+G+ ++ G G
Sbjct: 67 EFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLG 126
Query: 172 PTKKKAKMRAAELALRSFVQFPNACQAHLAMGGGP 206
KK+++ AA+LAL +Q L G P
Sbjct: 127 QNKKESRSNAAKLALDELLQLDEPEPRILETSGPP 161
>gi|21245124 adenosine deaminase domain containing 1
(testis-specific) isoform 1 [Homo sapiens]
Length = 576
Score = 158 bits (400), Expect = 2e-38
Identities = 141/470 (30%), Positives = 219/470 (46%), Gaps = 63/470 (13%)
Query: 306 FVMAVSVDGRTFE-GSGRSKKLARGQAAQAALQELFDIQMP--------GHAPGRARRTP 356
F VDG ++ G G++KK +R AA+ AL EL + P G P A
Sbjct: 128 FAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVV 187
Query: 357 MPQ--------------EFADSISQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDAR 402
+ + ++A ISQ+V ++F ++ ++ + +LA ++ + A
Sbjct: 188 LSELAYVSKVHYEGRHIQYA-KISQIVKERFNQLISNRSEYLKYSSSLAAFIIER---AG 243
Query: 403 QAQVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSER 462
Q +VVA+ +G S + + G V++D HA V ARR+ L + Y QL L SK E+
Sbjct: 244 QHEVVAIGTGEYNYS-QDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEK 302
Query: 463 SIFVRLKEGGY-RLRENILFHLYVSTSPCGDARLHSPYEITTDLHSSKHLVRKFRGHLRT 521
SIF L++NI LY++ P G A++ S L + H + F +
Sbjct: 303 SIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQIKS------QLRLNPHSISAFEANEEL 356
Query: 522 KIESGEGTVPVRGPSAVQTW---DGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEP 578
+ V V G + + DGV ++ +MS +DK+ RW VLG+QGALLSHF++P
Sbjct: 357 CLH-----VAVEGKIYLTVYCPKDGV---NRISSMSSSDKLTRWEVLGVQGALLSHFIQP 408
Query: 579 VYLQSIVV--GSLHHTGHLARVMSHRMEG--VGQLPASYRHNRPLLSGVSDAEARQPGKS 634
VY+ SI++ G+ T L + R++ +LP Y NRP +S V A Q
Sbjct: 409 VYISSILIGDGNCSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLE 468
Query: 635 PPF-SMNWVVGSADLEIINATTGRRSCGGP--------SRLCKHVLSARWARLYGRLSTR 685
F S+NW G LEI++ +G+ + P SRLCK + +R+ L
Sbjct: 469 YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKE 528
Query: 686 TPSPGDTPSMYCEAKLGAHTYQSVKQQLFKAFQKAGLGTWVRKPPEQQQF 735
G Y AK + +YQ K +L Q+ G G+W+ K P +QF
Sbjct: 529 LLEAG----TYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQF 574
Score = 38.9 bits (89), Expect = 0.017
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Query: 114 QLVWKKLSWSVAPKNALVQLHEL-RPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFE-GTG 171
+ + K + P +AL Q ++ R L + TG V P FA V+G+ ++ G G
Sbjct: 85 EFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLG 144
Query: 172 PTKKKAKMRAAELALRSFVQFPNACQAHLAMGGGP 206
KK+++ AA+LAL +Q L G P
Sbjct: 145 QNKKESRSNAAKLALDELLQLDEPEPRILETSGPP 179
>gi|226529650 adenosine deaminase domain containing 1
(testis-specific) isoform 2 [Homo sapiens]
Length = 565
Score = 143 bits (361), Expect = 5e-34
Identities = 137/470 (29%), Positives = 214/470 (45%), Gaps = 74/470 (15%)
Query: 306 FVMAVSVDGRTFE-GSGRSKKLARGQAAQAALQELFDIQMP--------GHAPGRARRTP 356
F VDG ++ G G++KK +R AA+ AL EL + P G P A
Sbjct: 128 FAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVV 187
Query: 357 MPQ--------------EFADSISQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDAR 402
+ + ++A ISQ+V ++F ++ ++ + +LA ++ + A
Sbjct: 188 LSELAYVSKVHYEGRHIQYA-KISQIVKERFNQLISNRSEYLKYSSSLAAFIIER---AG 243
Query: 403 QAQVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSER 462
Q +VVA+ +G S + + G V++D HA V ARR+ L SK E+
Sbjct: 244 QHEVVAIGTGEYNYS-QDIKPDGRVLHDTHAVVTARRSLL-----------SKNPAMMEK 291
Query: 463 SIFVRLKEGGY-RLRENILFHLYVSTSPCGDARLHSPYEITTDLHSSKHLVRKFRGHLRT 521
SIF L++NI LY++ P G A++ S L + H + F +
Sbjct: 292 SIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQIKS------QLRLNPHSISAFEANEEL 345
Query: 522 KIESGEGTVPVRGPSAVQTW---DGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEP 578
+ V V G + + DGV ++ +MS +DK+ RW VLG+QGALLSHF++P
Sbjct: 346 CLH-----VAVEGKIYLTVYCPKDGV---NRISSMSSSDKLTRWEVLGVQGALLSHFIQP 397
Query: 579 VYLQSIVV--GSLHHTGHLARVMSHRMEG--VGQLPASYRHNRPLLSGVSDAEARQPGKS 634
VY+ SI++ G+ T L + R++ +LP Y NRP +S V A Q
Sbjct: 398 VYISSILIGDGNCSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLE 457
Query: 635 PPF-SMNWVVGSADLEIINATTGRRSCGGP--------SRLCKHVLSARWARLYGRLSTR 685
F S+NW G LEI++ +G+ + P SRLCK + +R+ L
Sbjct: 458 YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKE 517
Query: 686 TPSPGDTPSMYCEAKLGAHTYQSVKQQLFKAFQKAGLGTWVRKPPEQQQF 735
G Y AK + +YQ K +L Q+ G G+W+ K P +QF
Sbjct: 518 LLEAG----TYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQF 563
Score = 38.9 bits (89), Expect = 0.017
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Query: 114 QLVWKKLSWSVAPKNALVQLHEL-RPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFE-GTG 171
+ + K + P +AL Q ++ R L + TG V P FA V+G+ ++ G G
Sbjct: 85 EFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLG 144
Query: 172 PTKKKAKMRAAELALRSFVQFPNACQAHLAMGGGP 206
KK+++ AA+LAL +Q L G P
Sbjct: 145 QNKKESRSNAAKLALDELLQLDEPEPRILETSGPP 179
>gi|223972690 adenosine deaminase domain containing 2 isoform 2
[Homo sapiens]
Length = 583
Score = 135 bits (339), Expect = 2e-31
Identities = 140/487 (28%), Positives = 214/487 (43%), Gaps = 52/487 (10%)
Query: 274 PGERNPVVLLNRLRAGLRYVCLAEPAERRARSFVMAVS--VDGRTFE-GSGRSKKLARGQ 330
P V LL A L L + F +VS +DG G+ SK A+ Q
Sbjct: 111 PPASQAVSLLTEYAASLGIFLLFREDQPPGPCFPFSVSAELDGVVCPAGTANSKTEAKQQ 170
Query: 331 AAQAALQELFDIQMPGHAPGRARRTPMPQEFADSI-------SQLVTQKFREVTTDLTPM 383
AA +AL + +P + R P+ ++I + LV+ F + + +P
Sbjct: 171 AALSALCYIRSQLENPESPQTSSRPPLAPLSVENILTHEQRCAALVSAGFDLLLDERSPY 230
Query: 384 HARHKALAGIVMTKGLDARQAQV------VALSSGTKCISGEHLSDQGLVVNDCHAEVVA 437
A +AG+++ + + + V VAL +G+ C +G L G ++DCH V+A
Sbjct: 231 WACKGTVAGVILEREIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIA 289
Query: 438 RRAFLHFLYTQLELHLSKRREDSERSIFVRLKEGG--YRLRENILFHLYVSTSPCGDAR- 494
RRA L FL+ QL L + E+S+ G + L+ + HLY+S +P G AR
Sbjct: 290 RRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARD 349
Query: 495 LHSPYEITTDLHSSKHLVRKFRGHLRTKIESGEGTVPVRGPSAVQTWDGVLLGEQLITMS 554
++ P L S + + + H+ +++ V PS T G L S
Sbjct: 350 IYLPPTSEGGLPHSPPM--RLQAHVLGQLKP----VCYVAPSLCDTHVGCL--------S 395
Query: 555 CTDKIARWNVLGLQGALLSHFVEPVYLQSIVVG-SLHHTGHLARVMSHR-----MEGVGQ 608
+DK+ARW VLGL GALL+H V P+Y S+++ S H L+R + R + G
Sbjct: 396 ASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCL 455
Query: 609 LPASYRHNRPLLSGVSDAEAR-QPGKSPPFSMNWVVGSADLEIINATTGR----RSCGGP 663
P R L +G A + P S+NW +G +E+++ TGR + G P
Sbjct: 456 PPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALGPP 515
Query: 664 SRLCKHVLSARWARLYGRLSTRTPSPGDTP-SMYCEAKLGAHTYQSVKQQLFKAFQKAGL 722
SRLCK A + R + + + P Y AK G YQ ++QL + GL
Sbjct: 516 SRLCK----ASFLRAFHQAARAVGKPYLLALKTYEAAKAG--PYQEARRQLSLLLDQQGL 569
Query: 723 GTWVRKP 729
G W KP
Sbjct: 570 GAWPSKP 576
>gi|223972688 adenosine deaminase domain containing 2 isoform 1
[Homo sapiens]
Length = 665
Score = 130 bits (327), Expect = 4e-30
Identities = 131/463 (28%), Positives = 205/463 (44%), Gaps = 60/463 (12%)
Query: 306 FVMAVSVDGRTFE-GSGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRTPMPQEFADS 364
F ++ +DG G+ SK A+ QAA +AL + +P + R P+ ++
Sbjct: 217 FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAPLSVEN 276
Query: 365 I-------SQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDARQA------------- 404
I + LV+ F + + +P A +AG+++ +G
Sbjct: 277 ILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSCTEIPRARGHVK 336
Query: 405 ---QVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSE 461
++VAL +G+ C +G L G ++DCH V+ARRA L FL+ QL L + E
Sbjct: 337 EIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKE 395
Query: 462 RSIFVRLKEGG--YRLRENILFHLYVSTSPCGDAR-LHSPYEITTDLHSSKHLVRKFRGH 518
+S+ G + L+ + HLY+S +P G AR ++ P L S + + + H
Sbjct: 396 QSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLPPTSEGGLPHSPPM--RLQAH 453
Query: 519 LRTKIESGEGTVPVRGPSAVQTWDGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEP 578
+ +++ V PS T G L S +DK+ARW VLGL GALL+H V P
Sbjct: 454 VLGQLKP----VCYVAPSLCDTHVGCL--------SASDKLARWAVLGLGGALLAHLVSP 501
Query: 579 VYLQSIVVG-SLHHTGHLARVMSHR-----MEGVGQLPASYRHNRPLLSGVSDAEAR-QP 631
+Y S+++ S H L+R + R + G P R L +G A + P
Sbjct: 502 LYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTP 561
Query: 632 GKSPPFSMNWVVGSADLEIINATTGR----RSCGGPSRLCKHVLSARWARLYGRLSTRTP 687
S+NW +G +E+++ TGR + G PSRLCK A + R + + +
Sbjct: 562 DTCRGLSLNWSLGDPGIEVVDVATGRVKANAALGPPSRLCK----ASFLRAFHQAARAVG 617
Query: 688 SPGDTP-SMYCEAKLGAHTYQSVKQQLFKAFQKAGLGTWVRKP 729
P Y AK G YQ ++QL + GLG W KP
Sbjct: 618 KPYLLALKTYEAAKAG--PYQEARRQLSLLLDQQGLGAWPSKP 658
>gi|24234756 interleukin enhancer binding factor 3 isoform c [Homo
sapiens]
Length = 690
Score = 129 bits (323), Expect = 1e-29
Identities = 100/303 (33%), Positives = 147/303 (48%), Gaps = 36/303 (11%)
Query: 60 DTLSTSSAEVKENRNVGNLAARPPPSGDRARGGAPGAKRKRPLEEGNG--GHLCKLQLVW 117
D L + + +N N + + PPS A KRP+EE K + +
Sbjct: 337 DPLPSKMPKKPKNENPVDYTVQIPPSTTYAI-----TPMKRPMEEDGEEKSPSKKKKKIQ 391
Query: 118 KKLSWSVAPK--NALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKK 175
KK + P+ NAL++L++L+PGLQY+ VSQTGPVHAP+F ++VEV+G +FE +GP+KK
Sbjct: 392 KKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKK 451
Query: 176 KAKMRAAELALRSFVQFPNACQAHLAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPG 235
AK+ A L+ + P A G G D + P + AP P
Sbjct: 452 TAKLHVAVKVLQD-MGLPTG-----AEGRDSSKGEDSAEETEAKPAVV-------APAPV 498
Query: 236 LAGGRPGDAALLSAAYGRRRLLCRALDLVGPTPATPAAPGERNPVVLLNRLRAGLRYVCL 295
+ AA S A + GP +NPV+ LN R GL+Y +
Sbjct: 499 VEAVSTPSAAFPSDATAEQ----------GPI----LTKHGKNPVMELNEKRRGLKYELI 544
Query: 296 AEPAERRARSFVMAVSVDGRTFEGSGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRT 355
+E + FVM V VDG+ F+G+G +KK+A+ AA AAL++LF + +R
Sbjct: 545 SETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRA 604
Query: 356 PMP 358
P+P
Sbjct: 605 PVP 607
Score = 55.5 bits (132), Expect = 2e-07
Identities = 44/124 (35%), Positives = 60/124 (48%), Gaps = 11/124 (8%)
Query: 127 KNALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELAL 186
KN +++L+E R GL+Y +S+TG H F + VEV+G F+G G KK AK AA AL
Sbjct: 526 KNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAAL 585
Query: 187 -RSFVQFPNACQAH------LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAG- 238
+ F P A A+ + + GGP + + E PP P L G
Sbjct: 586 EKLFPDTPLALDANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPP---PNLRGR 642
Query: 239 GRPG 242
GR G
Sbjct: 643 GRGG 646
>gi|24234753 interleukin enhancer binding factor 3 isoform b [Homo
sapiens]
Length = 702
Score = 129 bits (323), Expect = 1e-29
Identities = 100/303 (33%), Positives = 147/303 (48%), Gaps = 36/303 (11%)
Query: 60 DTLSTSSAEVKENRNVGNLAARPPPSGDRARGGAPGAKRKRPLEEGNG--GHLCKLQLVW 117
D L + + +N N + + PPS A KRP+EE K + +
Sbjct: 337 DPLPSKMPKKPKNENPVDYTVQIPPSTTYAI-----TPMKRPMEEDGEEKSPSKKKKKIQ 391
Query: 118 KKLSWSVAPK--NALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKK 175
KK + P+ NAL++L++L+PGLQY+ VSQTGPVHAP+F ++VEV+G +FE +GP+KK
Sbjct: 392 KKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKK 451
Query: 176 KAKMRAAELALRSFVQFPNACQAHLAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPG 235
AK+ A L+ + P A G G D + P + AP P
Sbjct: 452 TAKLHVAVKVLQD-MGLPTG-----AEGRDSSKGEDSAEETEAKPAVV-------APAPV 498
Query: 236 LAGGRPGDAALLSAAYGRRRLLCRALDLVGPTPATPAAPGERNPVVLLNRLRAGLRYVCL 295
+ AA S A + GP +NPV+ LN R GL+Y +
Sbjct: 499 VEAVSTPSAAFPSDATAEQ----------GPI----LTKHGKNPVMELNEKRRGLKYELI 544
Query: 296 AEPAERRARSFVMAVSVDGRTFEGSGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRT 355
+E + FVM V VDG+ F+G+G +KK+A+ AA AAL++LF + +R
Sbjct: 545 SETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRA 604
Query: 356 PMP 358
P+P
Sbjct: 605 PVP 607
Score = 55.5 bits (132), Expect = 2e-07
Identities = 44/124 (35%), Positives = 60/124 (48%), Gaps = 11/124 (8%)
Query: 127 KNALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELAL 186
KN +++L+E R GL+Y +S+TG H F + VEV+G F+G G KK AK AA AL
Sbjct: 526 KNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAAL 585
Query: 187 -RSFVQFPNACQAH------LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAG- 238
+ F P A A+ + + GGP + + E PP P L G
Sbjct: 586 EKLFPDTPLALDANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPP---PNLRGR 642
Query: 239 GRPG 242
GR G
Sbjct: 643 GRGG 646
>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
sapiens]
Length = 894
Score = 129 bits (323), Expect = 1e-29
Identities = 100/303 (33%), Positives = 147/303 (48%), Gaps = 36/303 (11%)
Query: 60 DTLSTSSAEVKENRNVGNLAARPPPSGDRARGGAPGAKRKRPLEEGNG--GHLCKLQLVW 117
D L + + +N N + + PPS A KRP+EE K + +
Sbjct: 337 DPLPSKMPKKPKNENPVDYTVQIPPSTTYAI-----TPMKRPMEEDGEEKSPSKKKKKIQ 391
Query: 118 KKLSWSVAPK--NALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKK 175
KK + P+ NAL++L++L+PGLQY+ VSQTGPVHAP+F ++VEV+G +FE +GP+KK
Sbjct: 392 KKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKK 451
Query: 176 KAKMRAAELALRSFVQFPNACQAHLAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPG 235
AK+ A L+ + P A G G D + P + AP P
Sbjct: 452 TAKLHVAVKVLQD-MGLPTG-----AEGRDSSKGEDSAEETEAKPAVV-------APAPV 498
Query: 236 LAGGRPGDAALLSAAYGRRRLLCRALDLVGPTPATPAAPGERNPVVLLNRLRAGLRYVCL 295
+ AA S A + GP +NPV+ LN R GL+Y +
Sbjct: 499 VEAVSTPSAAFPSDATAEQ----------GPI----LTKHGKNPVMELNEKRRGLKYELI 544
Query: 296 AEPAERRARSFVMAVSVDGRTFEGSGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRT 355
+E + FVM V VDG+ F+G+G +KK+A+ AA AAL++LF + +R
Sbjct: 545 SETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRA 604
Query: 356 PMP 358
P+P
Sbjct: 605 PVP 607
Score = 55.5 bits (132), Expect = 2e-07
Identities = 44/124 (35%), Positives = 60/124 (48%), Gaps = 11/124 (8%)
Query: 127 KNALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELAL 186
KN +++L+E R GL+Y +S+TG H F + VEV+G F+G G KK AK AA AL
Sbjct: 526 KNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAAL 585
Query: 187 -RSFVQFPNACQAH------LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAG- 238
+ F P A A+ + + GGP + + E PP P L G
Sbjct: 586 EKLFPDTPLALDANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPP---PNLRGR 642
Query: 239 GRPG 242
GR G
Sbjct: 643 GRGG 646
>gi|212549555 interleukin enhancer binding factor 3 isoform e [Homo
sapiens]
Length = 706
Score = 128 bits (322), Expect = 2e-29
Identities = 100/303 (33%), Positives = 147/303 (48%), Gaps = 32/303 (10%)
Query: 60 DTLSTSSAEVKENRNVGNLAARPPPSGDRARGGAPGAKRKRPLEEGNG--GHLCKLQLVW 117
D L + + +N N + + PPS A KRP+EE K + +
Sbjct: 337 DPLPSKMPKKPKNENPVDYTVQIPPSTTYAI-----TPMKRPMEEDGEEKSPSKKKKKIQ 391
Query: 118 KKLSWSVAPK--NALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKK 175
KK + P+ NAL++L++L+PGLQY+ VSQTGPVHAP+F ++VEV+G +FE +GP+KK
Sbjct: 392 KKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKK 451
Query: 176 KAKMRAAELALRSFVQFPNACQAHLAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPG 235
AK+ A L+ + P A G G D + P + AP P
Sbjct: 452 TAKLHVAVKVLQD-MGLPTG-----AEGRDSSKGEDSAEETEAKPAVV-------APAPV 498
Query: 236 LAGGRPGDAALLSAAYGRRRLLCRALDLVGPTPATPAAPGERNPVVLLNRLRAGLRYVCL 295
+ AA S A + GP +NPV+ LN R GL+Y +
Sbjct: 499 VEAVSTPSAAFPSDATAEN------VKQQGPI----LTKHGKNPVMELNEKRRGLKYELI 548
Query: 296 AEPAERRARSFVMAVSVDGRTFEGSGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRT 355
+E + FVM V VDG+ F+G+G +KK+A+ AA AAL++LF + +R
Sbjct: 549 SETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRA 608
Query: 356 PMP 358
P+P
Sbjct: 609 PVP 611
Score = 55.5 bits (132), Expect = 2e-07
Identities = 44/124 (35%), Positives = 60/124 (48%), Gaps = 11/124 (8%)
Query: 127 KNALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELAL 186
KN +++L+E R GL+Y +S+TG H F + VEV+G F+G G KK AK AA AL
Sbjct: 530 KNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAAL 589
Query: 187 -RSFVQFPNACQAH------LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAG- 238
+ F P A A+ + + GGP + + E PP P L G
Sbjct: 590 EKLFPDTPLALDANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPP---PNLRGR 646
Query: 239 GRPG 242
GR G
Sbjct: 647 GRGG 650
>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
sapiens]
Length = 898
Score = 128 bits (322), Expect = 2e-29
Identities = 100/303 (33%), Positives = 147/303 (48%), Gaps = 32/303 (10%)
Query: 60 DTLSTSSAEVKENRNVGNLAARPPPSGDRARGGAPGAKRKRPLEEGNG--GHLCKLQLVW 117
D L + + +N N + + PPS A KRP+EE K + +
Sbjct: 337 DPLPSKMPKKPKNENPVDYTVQIPPSTTYAI-----TPMKRPMEEDGEEKSPSKKKKKIQ 391
Query: 118 KKLSWSVAPK--NALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKK 175
KK + P+ NAL++L++L+PGLQY+ VSQTGPVHAP+F ++VEV+G +FE +GP+KK
Sbjct: 392 KKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKK 451
Query: 176 KAKMRAAELALRSFVQFPNACQAHLAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPG 235
AK+ A L+ + P A G G D + P + AP P
Sbjct: 452 TAKLHVAVKVLQD-MGLPTG-----AEGRDSSKGEDSAEETEAKPAVV-------APAPV 498
Query: 236 LAGGRPGDAALLSAAYGRRRLLCRALDLVGPTPATPAAPGERNPVVLLNRLRAGLRYVCL 295
+ AA S A + GP +NPV+ LN R GL+Y +
Sbjct: 499 VEAVSTPSAAFPSDATAEN------VKQQGPI----LTKHGKNPVMELNEKRRGLKYELI 548
Query: 296 AEPAERRARSFVMAVSVDGRTFEGSGRSKKLARGQAAQAALQELFDIQMPGHAPGRARRT 355
+E + FVM V VDG+ F+G+G +KK+A+ AA AAL++LF + +R
Sbjct: 549 SETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRA 608
Query: 356 PMP 358
P+P
Sbjct: 609 PVP 611
Score = 55.5 bits (132), Expect = 2e-07
Identities = 44/124 (35%), Positives = 60/124 (48%), Gaps = 11/124 (8%)
Query: 127 KNALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELAL 186
KN +++L+E R GL+Y +S+TG H F + VEV+G F+G G KK AK AA AL
Sbjct: 530 KNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAAL 589
Query: 187 -RSFVQFPNACQAH------LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAG- 238
+ F P A A+ + + GGP + + E PP P L G
Sbjct: 590 EKLFPDTPLALDANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPP---PNLRGR 646
Query: 239 GRPG 242
GR G
Sbjct: 647 GRGG 650
>gi|21361745 spermatid perinuclear RNA binding protein [Homo
sapiens]
Length = 672
Score = 121 bits (303), Expect = 3e-27
Identities = 83/254 (32%), Positives = 136/254 (53%), Gaps = 32/254 (12%)
Query: 92 GAPGAKRKRPLEEGNGGHLCKLQLVWKKL-----SWSVAPKNALVQLHELRPGLQYRTVS 146
GA + KRP E+G G + + + L S ++ NAL++L+++RPGLQY+ +S
Sbjct: 349 GAGSSALKRPFEDGLGDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLLS 408
Query: 147 QTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALRSFVQFPNACQAHLAMGGGP 206
Q+GPVHAPVF ++V+V+G T+E +GP+KK AK+ A L++ + +P A +
Sbjct: 409 QSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQA-MGYPTGFDADIEC---- 463
Query: 207 GPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCRALDLVGP 266
+D SD +T+ + G++ +++ L++
Sbjct: 464 -MSSDEKSDNESKNETVSSN----------SSNNTGNSTTETSS---------TLEVRTQ 503
Query: 267 TPATPAAPGERNPVVLLNRLRAGLRYVCLAEPAERRARSFVMAVSVDGRTFEGSGRSKKL 326
P A+ +NPV+ LN R GL+Y ++E + FVM V VDG+ F G+G +KK+
Sbjct: 504 GPILTAS--GKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKV 561
Query: 327 ARGQAAQAALQELF 340
A+ AA AAL++LF
Sbjct: 562 AKASAALAALEKLF 575
Score = 61.6 bits (148), Expect = 3e-09
Identities = 32/69 (46%), Positives = 41/69 (59%)
Query: 127 KNALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELAL 186
KN +++L+E R GL+Y +S+TG H F + VEV+G F G GP KK AK AA AL
Sbjct: 512 KNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAAL 571
Query: 187 RSFVQFPNA 195
PNA
Sbjct: 572 EKLFSGPNA 580
>gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens]
Length = 502
Score = 73.2 bits (178), Expect = 8e-13
Identities = 63/216 (29%), Positives = 100/216 (46%), Gaps = 32/216 (14%)
Query: 547 GEQLITMSCTDKIARWNVLGLQGALLSHFV-EPVYLQSIVVGSLHHTGH-LARVMSHRME 604
G++ +MSC+DK+ARWNVLG QGALL H + EP+YL ++V+G ++ + R + R +
Sbjct: 291 GDRTRSMSCSDKMARWNVLGCQGALLMHLLEEPIYLSAVVIGKCPYSQEAMQRALIGRCQ 350
Query: 605 GVGQLPASYRHNRPLL-----------SGVSDAEARQPGKSPP--FSMNW-VVGSADLEI 650
V LP + + S V A PG+ P +++W V L++
Sbjct: 351 NVSALPKGFGVQELKILQSDLLFEQSRSAVQAKRADSPGRLVPCGAAISWSAVPEQPLDV 410
Query: 651 I-----NATTGRR--SCGGPSRLCKHVLSARWARLYGRLSTRTPSPGDTP----SMYCEA 699
TT + S S++ K L + +L R++ R P Y E
Sbjct: 411 TANGFPQGTTKKTIGSLQARSQISKVELFRSFQKLLSRIA-RDKWPHSLRVQKLDTYQEY 469
Query: 700 KLGAHTYQSVKQQLFKAFQKAGLGTWVRKPPEQQQF 735
K A +Y Q+ + +K G+W+R PP+ QF
Sbjct: 470 KEAASSY----QEAWSTLRKQVFGSWIRNPPDYHQF 501
Score = 70.1 bits (170), Expect = 7e-12
Identities = 36/92 (39%), Positives = 60/92 (65%), Gaps = 5/92 (5%)
Query: 405 QVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSERSI 464
++V++ +GTKCI + G ++ND HAEV+ARR+F +L QL+L + + E SI
Sbjct: 60 EIVSMGTGTKCIGQSKMRKNGDILNDSHAEVIARRSFQRYLLHQLQLAATLK----EDSI 115
Query: 465 FV-RLKEGGYRLRENILFHLYVSTSPCGDARL 495
FV ++G ++LR +++F + S +PCGDA +
Sbjct: 116 FVPGTQKGVWKLRRDLIFVFFSSHTPCGDASI 147
>gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 49.7 bits (117), Expect = 1e-05
Identities = 56/208 (26%), Positives = 80/208 (38%), Gaps = 30/208 (14%)
Query: 142 YRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALRSFVQFPNACQAHLA 201
Y + G H P F V V + G GP+KK AK +AAE+AL+ HL
Sbjct: 27 YDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALK-----------HLK 75
Query: 202 MGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCRAL 261
G P + +S + +L ++ P A +A +L R+
Sbjct: 76 GGSMLEPALEDSSSFSPLDSSLPEDI-------------PVFTAAAAATPVPSVVLTRSP 122
Query: 262 DLVGPTPATPAAPGERNPVVLLNRL--RAGLR---YVCLAEPAERRARSFVMAVSVDGRT 316
+ P +P E NPV L L + G R Y E + F M V+
Sbjct: 123 PMELQPPVSP-QQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFI 181
Query: 317 FEGSGRSKKLARGQAAQAALQELFDIQM 344
GSG SKKLA+ AA L + + +
Sbjct: 182 EIGSGTSKKLAKRNAAAKMLLRVHTVPL 209
Score = 30.0 bits (66), Expect = 8.1
Identities = 14/42 (33%), Positives = 20/42 (47%)
Query: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAA 182
+Y ++GP H F + V G+G +KK AK AA
Sbjct: 156 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAA 197
>gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 49.7 bits (117), Expect = 1e-05
Identities = 56/208 (26%), Positives = 80/208 (38%), Gaps = 30/208 (14%)
Query: 142 YRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALRSFVQFPNACQAHLA 201
Y + G H P F V V + G GP+KK AK +AAE+AL+ HL
Sbjct: 48 YDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALK-----------HLK 96
Query: 202 MGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCRAL 261
G P + +S + +L ++ P A +A +L R+
Sbjct: 97 GGSMLEPALEDSSSFSPLDSSLPEDI-------------PVFTAAAAATPVPSVVLTRSP 143
Query: 262 DLVGPTPATPAAPGERNPVVLLNRL--RAGLR---YVCLAEPAERRARSFVMAVSVDGRT 316
+ P +P E NPV L L + G R Y E + F M V+
Sbjct: 144 PMELQPPVSP-QQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFI 202
Query: 317 FEGSGRSKKLARGQAAQAALQELFDIQM 344
GSG SKKLA+ AA L + + +
Sbjct: 203 EIGSGTSKKLAKRNAAAKMLLRVHTVPL 230
Score = 30.0 bits (66), Expect = 8.1
Identities = 14/42 (33%), Positives = 20/42 (47%)
Query: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAA 182
+Y ++GP H F + V G+G +KK AK AA
Sbjct: 177 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAA 218
>gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 49.7 bits (117), Expect = 1e-05
Identities = 56/208 (26%), Positives = 80/208 (38%), Gaps = 30/208 (14%)
Query: 142 YRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALRSFVQFPNACQAHLA 201
Y + G H P F V V + G GP+KK AK +AAE+AL+ HL
Sbjct: 27 YDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALK-----------HLK 75
Query: 202 MGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCRAL 261
G P + +S + +L ++ P A +A +L R+
Sbjct: 76 GGSMLEPALEDSSSFSPLDSSLPEDI-------------PVFTAAAAATPVPSVVLTRSP 122
Query: 262 DLVGPTPATPAAPGERNPVVLLNRL--RAGLR---YVCLAEPAERRARSFVMAVSVDGRT 316
+ P +P E NPV L L + G R Y E + F M V+
Sbjct: 123 PMELQPPVSP-QQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFI 181
Query: 317 FEGSGRSKKLARGQAAQAALQELFDIQM 344
GSG SKKLA+ AA L + + +
Sbjct: 182 EIGSGTSKKLAKRNAAAKMLLRVHTVPL 209
Score = 30.0 bits (66), Expect = 8.1
Identities = 14/42 (33%), Positives = 20/42 (47%)
Query: 141 QYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAA 182
+Y ++GP H F + V G+G +KK AK AA
Sbjct: 156 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAA 197
>gi|7657625 staufen homolog 2 [Homo sapiens]
Length = 479
Score = 49.3 bits (116), Expect = 1e-05
Identities = 49/200 (24%), Positives = 74/200 (37%), Gaps = 49/200 (24%)
Query: 140 LQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALRSFVQFPNACQAH 199
+ + + ++GP H F V V + EG G +KK +K RAA L+ + P
Sbjct: 191 VSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLP------ 244
Query: 200 LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCR 259
P P + P F++ RP YG+
Sbjct: 245 ------PLP-------VVEKPKLFFKK-------------RPKTIVKAGPEYGQ------ 272
Query: 260 ALDLVGPTPATPAAPGERNPVVLLNRLRAGLRYVCLAEPAERRARSFVMAVSVDGRTFEG 319
++ + A E+ P YV L+E R R FVM V V G
Sbjct: 273 GMNPISRLAQIQQAKKEKEP-----------DYVLLSERGMPRRREFVMQVKVGNEVATG 321
Query: 320 SGRSKKLARGQAAQAALQEL 339
+G +KK+A+ AA+A L +L
Sbjct: 322 TGPNKKIAKKNAAEAMLLQL 341
Score = 32.0 bits (71), Expect = 2.1
Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Query: 126 PKNALVQLHELRPGLQ--YRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAE 183
P + L Q+ + + + Y +S+ G F + V+V GTGP KK AK AAE
Sbjct: 276 PISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAE 335
Query: 184 LAL 186
L
Sbjct: 336 AML 338
Score = 30.4 bits (67), Expect = 6.2
Identities = 15/44 (34%), Positives = 25/44 (56%)
Query: 306 FVMAVSVDGRTFEGSGRSKKLARGQAAQAALQELFDIQMPGHAP 349
F + ++V F G G++++ AR AA ALQ L + +P +P
Sbjct: 114 FYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSP 157
>gi|82659089 staufen isoform a [Homo sapiens]
Length = 496
Score = 43.5 bits (101), Expect = 7e-04
Identities = 49/215 (22%), Positives = 75/215 (34%), Gaps = 58/215 (26%)
Query: 140 LQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALRSFVQFPNACQAH 199
+ + ++GP H F V V EG G +KK +K AA L + P
Sbjct: 119 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP------ 172
Query: 200 LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCR 259
P P + +P R+ +
Sbjct: 173 --------------------------------PLPAVERVKP-------------RIKKK 187
Query: 260 ALDLVGPTPATPAAPGERNPVVLLNRLRAGLR-----YVCLAEPAERRARSFVMAVSVDG 314
+V P + G NP+ L +++ + Y L E R R FVM V V
Sbjct: 188 TKPIVKPQTSPEYGQGI-NPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 246
Query: 315 RTFEGSGRSKKLARGQAAQAALQELFDIQMPGHAP 349
T EG+G +KK+A+ AA+ L E+ ++P P
Sbjct: 247 HTAEGTGTNKKVAKRNAAENML-EILGFKVPQAQP 280
Score = 32.3 bits (72), Expect = 1.6
Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 124 VAPKNALVQLHELRPGLQ--YRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRA 181
+ P + L Q+ + + + Y +++ G F + V+V T EGTG KK AK A
Sbjct: 204 INPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNA 263
Query: 182 AE 183
AE
Sbjct: 264 AE 265
>gi|82659087 staufen isoform b [Homo sapiens]
Length = 577
Score = 43.5 bits (101), Expect = 7e-04
Identities = 49/215 (22%), Positives = 75/215 (34%), Gaps = 58/215 (26%)
Query: 140 LQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALRSFVQFPNACQAH 199
+ + ++GP H F V V EG G +KK +K AA L + P
Sbjct: 200 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP------ 253
Query: 200 LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCR 259
P P + +P R+ +
Sbjct: 254 --------------------------------PLPAVERVKP-------------RIKKK 268
Query: 260 ALDLVGPTPATPAAPGERNPVVLLNRLRAGLR-----YVCLAEPAERRARSFVMAVSVDG 314
+V P + G NP+ L +++ + Y L E R R FVM V V
Sbjct: 269 TKPIVKPQTSPEYGQGI-NPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 327
Query: 315 RTFEGSGRSKKLARGQAAQAALQELFDIQMPGHAP 349
T EG+G +KK+A+ AA+ L E+ ++P P
Sbjct: 328 HTAEGTGTNKKVAKRNAAENML-EILGFKVPQAQP 361
Score = 32.3 bits (72), Expect = 1.6
Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 124 VAPKNALVQLHELRPGLQ--YRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRA 181
+ P + L Q+ + + + Y +++ G F + V+V T EGTG KK AK A
Sbjct: 285 INPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNA 344
Query: 182 AE 183
AE
Sbjct: 345 AE 346
>gi|82659085 staufen isoform a [Homo sapiens]
Length = 496
Score = 43.5 bits (101), Expect = 7e-04
Identities = 49/215 (22%), Positives = 75/215 (34%), Gaps = 58/215 (26%)
Query: 140 LQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALRSFVQFPNACQAH 199
+ + ++GP H F V V EG G +KK +K AA L + P
Sbjct: 119 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP------ 172
Query: 200 LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCR 259
P P + +P R+ +
Sbjct: 173 --------------------------------PLPAVERVKP-------------RIKKK 187
Query: 260 ALDLVGPTPATPAAPGERNPVVLLNRLRAGLR-----YVCLAEPAERRARSFVMAVSVDG 314
+V P + G NP+ L +++ + Y L E R R FVM V V
Sbjct: 188 TKPIVKPQTSPEYGQGI-NPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 246
Query: 315 RTFEGSGRSKKLARGQAAQAALQELFDIQMPGHAP 349
T EG+G +KK+A+ AA+ L E+ ++P P
Sbjct: 247 HTAEGTGTNKKVAKRNAAENML-EILGFKVPQAQP 280
Score = 32.3 bits (72), Expect = 1.6
Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 124 VAPKNALVQLHELRPGLQ--YRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRA 181
+ P + L Q+ + + + Y +++ G F + V+V T EGTG KK AK A
Sbjct: 204 INPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNA 263
Query: 182 AE 183
AE
Sbjct: 264 AE 265
>gi|82659083 staufen isoform a [Homo sapiens]
Length = 496
Score = 43.5 bits (101), Expect = 7e-04
Identities = 49/215 (22%), Positives = 75/215 (34%), Gaps = 58/215 (26%)
Query: 140 LQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALRSFVQFPNACQAH 199
+ + ++GP H F V V EG G +KK +K AA L + P
Sbjct: 119 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP------ 172
Query: 200 LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCR 259
P P + +P R+ +
Sbjct: 173 --------------------------------PLPAVERVKP-------------RIKKK 187
Query: 260 ALDLVGPTPATPAAPGERNPVVLLNRLRAGLR-----YVCLAEPAERRARSFVMAVSVDG 314
+V P + G NP+ L +++ + Y L E R R FVM V V
Sbjct: 188 TKPIVKPQTSPEYGQGI-NPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 246
Query: 315 RTFEGSGRSKKLARGQAAQAALQELFDIQMPGHAP 349
T EG+G +KK+A+ AA+ L E+ ++P P
Sbjct: 247 HTAEGTGTNKKVAKRNAAENML-EILGFKVPQAQP 280
Score = 32.3 bits (72), Expect = 1.6
Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 124 VAPKNALVQLHELRPGLQ--YRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRA 181
+ P + L Q+ + + + Y +++ G F + V+V T EGTG KK AK A
Sbjct: 204 INPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNA 263
Query: 182 AE 183
AE
Sbjct: 264 AE 265
>gi|82659091 staufen isoform c [Homo sapiens]
Length = 502
Score = 42.4 bits (98), Expect = 0.002
Identities = 49/208 (23%), Positives = 73/208 (35%), Gaps = 58/208 (27%)
Query: 147 QTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALRSFVQFPNACQAHLAMGGGP 206
++GP H F V V EG G +KK +K AA L + P
Sbjct: 132 ESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP------------- 178
Query: 207 GPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCRALDLVGP 266
P P + +P R+ + +V P
Sbjct: 179 -------------------------PLPAVERVKP-------------RIKKKTKPIVKP 200
Query: 267 TPATPAAPGERNPVVLLNRLRAGLR-----YVCLAEPAERRARSFVMAVSVDGRTFEGSG 321
+ G NP+ L +++ + Y L E R R FVM V V T EG+G
Sbjct: 201 QTSPEYGQGI-NPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTG 259
Query: 322 RSKKLARGQAAQAALQELFDIQMPGHAP 349
+KK+A+ AA+ L E+ ++P P
Sbjct: 260 TNKKVAKRNAAENML-EILGFKVPQAQP 286
Score = 32.3 bits (72), Expect = 1.6
Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 124 VAPKNALVQLHELRPGLQ--YRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRA 181
+ P + L Q+ + + + Y +++ G F + V+V T EGTG KK AK A
Sbjct: 210 INPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNA 269
Query: 182 AE 183
AE
Sbjct: 270 AE 271
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,276,731
Number of Sequences: 37866
Number of extensions: 1660607
Number of successful extensions: 5696
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 5468
Number of HSP's gapped (non-prelim): 166
length of query: 739
length of database: 18,247,518
effective HSP length: 110
effective length of query: 629
effective length of database: 14,082,258
effective search space: 8857740282
effective search space used: 8857740282
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.