Guide to the Human Genome
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Search of human proteins with 88952306

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|88952306 PREDICTED: similar to nuclear transport factor 2
[Homo sapiens]
         (126 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|88952306 PREDICTED: similar to nuclear transport factor 2 [Ho...   266   3e-72
gi|169160905 PREDICTED: similar to nuclear transport factor 2 [H...   264   1e-71
gi|17451119 PREDICTED: similar to nuclear transport factor 2 [Ho...   264   2e-71
gi|5031985 nuclear transport factor 2 [Homo sapiens]                  229   3e-61
gi|7019471 NTF2-like export factor 1 [Homo sapiens]                    38   0.002
gi|21361724 nuclear transport factor 2-like export factor 2 [Hom...    38   0.002
gi|19923399 Ras-GTPase activating protein SH3 domain-binding pro...    36   0.009
gi|45359849 Ras-GTPase activating protein SH3 domain-binding pro...    36   0.009
gi|45359846 Ras-GTPase activating protein SH3 domain-binding pro...    36   0.009
gi|5031703 Ras-GTPase-activating protein SH3-domain-binding prot...    33   0.058
gi|38327552 Ras-GTPase-activating protein SH3-domain-binding pro...    33   0.058
gi|239740950 PREDICTED: similar to mitogen-activated protein kin...    27   4.1  
gi|4885433 mitogen-activated protein kinase 8 interacting protei...    27   4.1  
gi|169211037 PREDICTED: similar to mitogen-activated protein kin...    27   5.4  
gi|34452681 ring finger protein 10 [Homo sapiens]                      27   5.4  
gi|37594449 Abl-philin 2 isoform 1 [Homo sapiens]                      26   9.2  
gi|37594455 Abl-philin 2 isoform 1 [Homo sapiens]                      26   9.2  
gi|32698946 hypothetical protein LOC283422 [Homo sapiens]              26   9.2  

>gi|88952306 PREDICTED: similar to nuclear transport factor 2 [Homo
           sapiens]
          Length = 126

 Score =  266 bits (680), Expect = 3e-72
 Identities = 126/126 (100%), Positives = 126/126 (100%)

Query: 1   MGDKPVWEPIGSSFNQHYYQLFDNDRTQLGAIYIDASCLTWEVRQFQGKAAAVEKLSSLP 60
           MGDKPVWEPIGSSFNQHYYQLFDNDRTQLGAIYIDASCLTWEVRQFQGKAAAVEKLSSLP
Sbjct: 1   MGDKPVWEPIGSSFNQHYYQLFDNDRTQLGAIYIDASCLTWEVRQFQGKAAAVEKLSSLP 60

Query: 61  FQKIQNSLRAQDHQPTPDSCIIGVVVGQLKADEDPIKGFHQMFLLKNINDGFCANDMFRF 120
           FQKIQNSLRAQDHQPTPDSCIIGVVVGQLKADEDPIKGFHQMFLLKNINDGFCANDMFRF
Sbjct: 61  FQKIQNSLRAQDHQPTPDSCIIGVVVGQLKADEDPIKGFHQMFLLKNINDGFCANDMFRF 120

Query: 121 ALHNFG 126
           ALHNFG
Sbjct: 121 ALHNFG 126


>gi|169160905 PREDICTED: similar to nuclear transport factor 2 [Homo
           sapiens]
          Length = 340

 Score =  264 bits (675), Expect = 1e-71
 Identities = 125/125 (100%), Positives = 125/125 (100%)

Query: 2   GDKPVWEPIGSSFNQHYYQLFDNDRTQLGAIYIDASCLTWEVRQFQGKAAAVEKLSSLPF 61
           GDKPVWEPIGSSFNQHYYQLFDNDRTQLGAIYIDASCLTWEVRQFQGKAAAVEKLSSLPF
Sbjct: 216 GDKPVWEPIGSSFNQHYYQLFDNDRTQLGAIYIDASCLTWEVRQFQGKAAAVEKLSSLPF 275

Query: 62  QKIQNSLRAQDHQPTPDSCIIGVVVGQLKADEDPIKGFHQMFLLKNINDGFCANDMFRFA 121
           QKIQNSLRAQDHQPTPDSCIIGVVVGQLKADEDPIKGFHQMFLLKNINDGFCANDMFRFA
Sbjct: 276 QKIQNSLRAQDHQPTPDSCIIGVVVGQLKADEDPIKGFHQMFLLKNINDGFCANDMFRFA 335

Query: 122 LHNFG 126
           LHNFG
Sbjct: 336 LHNFG 340


>gi|17451119 PREDICTED: similar to nuclear transport factor 2 [Homo
           sapiens]
          Length = 126

 Score =  264 bits (674), Expect = 2e-71
 Identities = 125/126 (99%), Positives = 125/126 (99%)

Query: 1   MGDKPVWEPIGSSFNQHYYQLFDNDRTQLGAIYIDASCLTWEVRQFQGKAAAVEKLSSLP 60
           MGDKPVWEPIGSSFNQHYYQLFDNDRTQLGAIYIDASCLTWEVRQFQGKAAAVEKLSSLP
Sbjct: 1   MGDKPVWEPIGSSFNQHYYQLFDNDRTQLGAIYIDASCLTWEVRQFQGKAAAVEKLSSLP 60

Query: 61  FQKIQNSLRAQDHQPTPDSCIIGVVVGQLKADEDPIKGFHQMFLLKNINDGFCANDMFRF 120
           FQKIQNSL AQDHQPTPDSCIIGVVVGQLKADEDPIKGFHQMFLLKNINDGFCANDMFRF
Sbjct: 61  FQKIQNSLTAQDHQPTPDSCIIGVVVGQLKADEDPIKGFHQMFLLKNINDGFCANDMFRF 120

Query: 121 ALHNFG 126
           ALHNFG
Sbjct: 121 ALHNFG 126


>gi|5031985 nuclear transport factor 2 [Homo sapiens]
          Length = 127

 Score =  229 bits (585), Expect = 3e-61
 Identities = 110/127 (86%), Positives = 116/127 (91%), Gaps = 1/127 (0%)

Query: 1   MGDKPVWEPIGSSFNQHYYQLFDNDRTQLGAIYIDASCLTWEVRQFQGKAAAVEKLSSLP 60
           MGDKP+WE IGSSF QHYYQLFDNDRTQLGAIYIDASCLTWE +QFQGKAA VEKLSSLP
Sbjct: 1   MGDKPIWEQIGSSFIQHYYQLFDNDRTQLGAIYIDASCLTWEGQQFQGKAAIVEKLSSLP 60

Query: 61  FQKIQNSLRAQDHQPTPDSCIIGVVVGQLKADEDPIKGFHQMFLLKNINDGF-CANDMFR 119
           FQKIQ+S+ AQDHQPTPDSCII +VVGQLKADEDPI GFHQMFLLKNIND + C NDMFR
Sbjct: 61  FQKIQHSITAQDHQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFR 120

Query: 120 FALHNFG 126
            ALHNFG
Sbjct: 121 LALHNFG 127


>gi|7019471 NTF2-like export factor 1 [Homo sapiens]
          Length = 140

 Score = 38.1 bits (87), Expect = 0.002
 Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 8/94 (8%)

Query: 18  YYQLFDNDRTQLGAIYIDASCLTWEVRQFQGKAAAVEKLSSLPFQKIQNSLRAQDHQPTP 77
           YY   D  R  L  +Y+  + L W      G+ +  E    LP  + Q S+   D QP  
Sbjct: 24  YYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSEFFEMLPSSEFQISV--VDCQPVH 81

Query: 78  D------SCIIGVVVGQLKADEDPIKGFHQMFLL 105
           D      + ++ V+ G +K + +  + F+Q F+L
Sbjct: 82  DEATPSQTTVLVVICGSVKFEGNKQRDFNQNFIL 115


>gi|21361724 nuclear transport factor 2-like export factor 2 [Homo
           sapiens]
          Length = 197

 Score = 37.7 bits (86), Expect = 0.002
 Identities = 34/112 (30%), Positives = 47/112 (41%), Gaps = 9/112 (8%)

Query: 18  YYQLFDNDRTQLGAIYIDASCLTWEVRQFQGKAAAVEKLSSLPFQKIQ-NSLRAQD-HQP 75
           YY+  D  R  L  +Y+D + L W      G  A      +LP  + Q N L  Q  H+ 
Sbjct: 80  YYETMDKRRRALTRLYLDKATLIWNGNAVSGLDALNNFFDTLPSSEFQVNMLDCQPVHEQ 139

Query: 76  TPDS--CIIGVVVGQLKADEDPIKGFHQMFLL-----KNINDGFCANDMFRF 120
              S   ++ V  G +K D +    F+Q FLL      N      A+D FRF
Sbjct: 140 ATQSQTTVLVVTSGTVKFDGNKQHFFNQNFLLTAQSTPNNTVWKIASDCFRF 191


>gi|19923399 Ras-GTPase activating protein SH3 domain-binding
           protein 2 isoform a [Homo sapiens]
          Length = 482

 Score = 35.8 bits (81), Expect = 0.009
 Identities = 37/138 (26%), Positives = 53/138 (38%), Gaps = 16/138 (11%)

Query: 3   DKPVWEPIGSSFNQHYYQLFDNDRTQLGAIY----------IDASCLTWEVRQFQGKAAA 52
           +KP    +G  F + YY L +     L   Y          +DAS    E     G+   
Sbjct: 4   EKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEA--VYGQNDI 61

Query: 53  VEKLSSLPFQKIQNSLRAQDHQPTPDSCIIGVVVGQLKADEDPIKGFHQMFLL----KNI 108
             K+ SL F +    +R  D   T    ++  V+G L     P + F Q F+L       
Sbjct: 62  HHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVP 121

Query: 109 NDGFCANDMFRFALHNFG 126
           N  +  NDMFR+    FG
Sbjct: 122 NKFYVHNDMFRYEDEVFG 139


>gi|45359849 Ras-GTPase activating protein SH3 domain-binding
           protein 2 isoform a [Homo sapiens]
          Length = 482

 Score = 35.8 bits (81), Expect = 0.009
 Identities = 37/138 (26%), Positives = 53/138 (38%), Gaps = 16/138 (11%)

Query: 3   DKPVWEPIGSSFNQHYYQLFDNDRTQLGAIY----------IDASCLTWEVRQFQGKAAA 52
           +KP    +G  F + YY L +     L   Y          +DAS    E     G+   
Sbjct: 4   EKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEA--VYGQNDI 61

Query: 53  VEKLSSLPFQKIQNSLRAQDHQPTPDSCIIGVVVGQLKADEDPIKGFHQMFLL----KNI 108
             K+ SL F +    +R  D   T    ++  V+G L     P + F Q F+L       
Sbjct: 62  HHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVP 121

Query: 109 NDGFCANDMFRFALHNFG 126
           N  +  NDMFR+    FG
Sbjct: 122 NKFYVHNDMFRYEDEVFG 139


>gi|45359846 Ras-GTPase activating protein SH3 domain-binding
           protein 2 isoform b [Homo sapiens]
          Length = 449

 Score = 35.8 bits (81), Expect = 0.009
 Identities = 37/138 (26%), Positives = 53/138 (38%), Gaps = 16/138 (11%)

Query: 3   DKPVWEPIGSSFNQHYYQLFDNDRTQLGAIY----------IDASCLTWEVRQFQGKAAA 52
           +KP    +G  F + YY L +     L   Y          +DAS    E     G+   
Sbjct: 4   EKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEA--VYGQNDI 61

Query: 53  VEKLSSLPFQKIQNSLRAQDHQPTPDSCIIGVVVGQLKADEDPIKGFHQMFLL----KNI 108
             K+ SL F +    +R  D   T    ++  V+G L     P + F Q F+L       
Sbjct: 62  HHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVP 121

Query: 109 NDGFCANDMFRFALHNFG 126
           N  +  NDMFR+    FG
Sbjct: 122 NKFYVHNDMFRYEDEVFG 139


>gi|5031703 Ras-GTPase-activating protein SH3-domain-binding protein
           [Homo sapiens]
          Length = 466

 Score = 33.1 bits (74), Expect = 0.058
 Identities = 33/136 (24%), Positives = 50/136 (36%), Gaps = 12/136 (8%)

Query: 3   DKPVWEPIGSSFNQHYYQLFDNDRTQLGAIYIDASCLTWEVRQFQGKAAAV--------E 54
           +KP    +G  F + YY L +     L   Y   S          GK A           
Sbjct: 4   EKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKPADAVYGQKEIHR 63

Query: 55  KLSSLPFQKIQNSLRAQDHQPTPDSCIIGVVVGQLKADEDPIKGFHQMFLL----KNIND 110
           K+ S  F      +R  D   T +  ++  V+G L  +   ++ F Q F+L       N 
Sbjct: 64  KVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANK 123

Query: 111 GFCANDMFRFALHNFG 126
            +  ND+FR+    FG
Sbjct: 124 FYVHNDIFRYQDEVFG 139


>gi|38327552 Ras-GTPase-activating protein SH3-domain-binding
           protein [Homo sapiens]
          Length = 466

 Score = 33.1 bits (74), Expect = 0.058
 Identities = 33/136 (24%), Positives = 50/136 (36%), Gaps = 12/136 (8%)

Query: 3   DKPVWEPIGSSFNQHYYQLFDNDRTQLGAIYIDASCLTWEVRQFQGKAAAV--------E 54
           +KP    +G  F + YY L +     L   Y   S          GK A           
Sbjct: 4   EKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKPADAVYGQKEIHR 63

Query: 55  KLSSLPFQKIQNSLRAQDHQPTPDSCIIGVVVGQLKADEDPIKGFHQMFLL----KNIND 110
           K+ S  F      +R  D   T +  ++  V+G L  +   ++ F Q F+L       N 
Sbjct: 64  KVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANK 123

Query: 111 GFCANDMFRFALHNFG 126
            +  ND+FR+    FG
Sbjct: 124 FYVHNDIFRYQDEVFG 139


>gi|239740950 PREDICTED: similar to mitogen-activated protein kinase
           8 interacting protein 1 [Homo sapiens]
          Length = 442

 Score = 26.9 bits (58), Expect = 4.1
 Identities = 20/59 (33%), Positives = 25/59 (42%), Gaps = 7/59 (11%)

Query: 58  SLPFQKIQNSLRAQDHQPTPDSCII-----GVVVGQLKADEDPIKG--FHQMFLLKNIN 109
           S   QKI  + R   H   P SC++     GV +G    D    KG      F LKNI+
Sbjct: 318 SAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADDSQEAKGNKCSHFFQLKNIS 376


>gi|4885433 mitogen-activated protein kinase 8 interacting protein 1
           [Homo sapiens]
          Length = 711

 Score = 26.9 bits (58), Expect = 4.1
 Identities = 21/59 (35%), Positives = 26/59 (44%), Gaps = 9/59 (15%)

Query: 62  QKIQNSLRAQDHQPTPDSCII-----GVVVGQLKADEDPIKG--FHQMFLLKNINDGFC 113
           QKI  + R   H   P SC++     GV +G    D    KG      F LKNI+  FC
Sbjct: 591 QKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADDSQEAKGNKCSHFFQLKNIS--FC 647


>gi|169211037 PREDICTED: similar to mitogen-activated protein kinase
           8 interacting protein 1 [Homo sapiens]
          Length = 423

 Score = 26.6 bits (57), Expect = 5.4
 Identities = 20/59 (33%), Positives = 25/59 (42%), Gaps = 7/59 (11%)

Query: 58  SLPFQKIQNSLRAQDHQPTPDSCII-----GVVVGQLKADEDPIKG--FHQMFLLKNIN 109
           S   QKI  + R   H   P SC++     GV +G    D    KG      F LKNI+
Sbjct: 299 SAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGIKADDSQEAKGNKCSHFFQLKNIS 357


>gi|34452681 ring finger protein 10 [Homo sapiens]
          Length = 811

 Score = 26.6 bits (57), Expect = 5.4
 Identities = 10/37 (27%), Positives = 20/37 (54%)

Query: 62  QKIQNSLRAQDHQPTPDSCIIGVVVGQLKADEDPIKG 98
           +K+    +  + + TP+SC I   + +LK  E+ + G
Sbjct: 348 EKVALEQQLAEEKHTPESCFIEAAIQELKTREEALSG 384


>gi|37594449 Abl-philin 2 isoform 1 [Homo sapiens]
          Length = 377

 Score = 25.8 bits (55), Expect = 9.2
 Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 5/64 (7%)

Query: 14  FNQHYYQLFDNDRTQLGAIYIDASCLTWEVRQFQGKAAAVEKLSSLPFQKIQNSLRAQDH 73
           +N  Y+  F    T LG +Y   S  +W++  F+   AA+EK+  L   K+Q       H
Sbjct: 195 YNHRYFFSFCFFMT-LGCVY--CSYGSWDL--FREAYAAIEKMKQLDKNKLQAVANQTYH 249

Query: 74  QPTP 77
           Q  P
Sbjct: 250 QTPP 253


>gi|37594455 Abl-philin 2 isoform 1 [Homo sapiens]
          Length = 377

 Score = 25.8 bits (55), Expect = 9.2
 Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 5/64 (7%)

Query: 14  FNQHYYQLFDNDRTQLGAIYIDASCLTWEVRQFQGKAAAVEKLSSLPFQKIQNSLRAQDH 73
           +N  Y+  F    T LG +Y   S  +W++  F+   AA+EK+  L   K+Q       H
Sbjct: 195 YNHRYFFSFCFFMT-LGCVY--CSYGSWDL--FREAYAAIEKMKQLDKNKLQAVANQTYH 249

Query: 74  QPTP 77
           Q  P
Sbjct: 250 QTPP 253


>gi|32698946 hypothetical protein LOC283422 [Homo sapiens]
          Length = 138

 Score = 25.8 bits (55), Expect = 9.2
 Identities = 14/43 (32%), Positives = 23/43 (53%), Gaps = 5/43 (11%)

Query: 39  LTWEVRQFQ-GKAAAVEKLSSLPFQKIQNSLRAQDHQPTPDSC 80
           + W +++ + G+ A +EK      QKI+  +R Q  Q T D C
Sbjct: 100 IAWRIQRLKSGQTALIEKKK----QKIEEDVRHQCQQTTCDRC 138


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,889,370
Number of Sequences: 37866
Number of extensions: 183092
Number of successful extensions: 341
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 333
Number of HSP's gapped (non-prelim): 18
length of query: 126
length of database: 18,247,518
effective HSP length: 90
effective length of query: 36
effective length of database: 14,839,578
effective search space: 534224808
effective search space used: 534224808
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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