Guide to the Human Genome
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Search of human proteins with 88758615

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
         (1039 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]           2115   0.0  
gi|49170034 integrin, alpha 8 [Homo sapiens]                          709   0.0  
gi|56237029 integrin alpha 5 precursor [Homo sapiens]                 649   0.0  
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]        630   e-180
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]                604   e-172
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]      590   e-168
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]      287   4e-77
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]      282   1e-75
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]        269   1e-71
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]        267   4e-71
gi|52485941 integrin, alpha 9 precursor [Homo sapiens]                249   1e-65
gi|67191027 integrin alpha 4 precursor [Homo sapiens]                 248   2e-65
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]                246   8e-65
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [...   236   8e-62
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [...   235   1e-61
gi|31657142 integrin, alpha 1 precursor [Homo sapiens]                187   3e-47
gi|62548866 integrin, alpha D precursor [Homo sapiens]                170   6e-42
gi|116295258 integrin alpha 2 precursor [Homo sapiens]                169   2e-41
gi|38569398 integrin, alpha 10 precursor [Homo sapiens]               156   8e-38
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]      149   1e-35
gi|34452173 integrin alpha X precursor [Homo sapiens]                 145   1e-34
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]       145   2e-34
gi|52485853 integrin, alpha 11 precursor [Homo sapiens]               142   1e-33
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]      140   6e-33
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]      138   2e-32
gi|148728188 integrin, alpha E precursor [Homo sapiens]               130   8e-30
gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ...    60   1e-08
gi|29171717 glycosylphosphatidylinositol specific phospholipase ...    54   6e-07
gi|153945755 zinc finger protein 608 [Homo sapiens]                    35   0.48 
gi|31652264 RNA binding motif protein 26 [Homo sapiens]                35   0.48 

>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
          Length = 1039

 Score = 2115 bits (5479), Expect = 0.0
 Identities = 1039/1039 (100%), Positives = 1039/1039 (100%)

Query: 1    MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDS 60
            MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDS
Sbjct: 1    MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDS 60

Query: 61   HGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKA 120
            HGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKA
Sbjct: 61   HGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKA 120

Query: 121  RQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGN 180
            RQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGN
Sbjct: 121  RQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGN 180

Query: 181  TLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRP 240
            TLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRP
Sbjct: 181  TLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRP 240

Query: 241  GILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEI 300
            GILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEI
Sbjct: 241  GILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEI 300

Query: 301  LDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVY 360
            LDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVY
Sbjct: 301  LDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVY 360

Query: 361  LFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQV 420
            LFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQV
Sbjct: 361  LFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQV 420

Query: 421  LVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYR 480
            LVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYR
Sbjct: 421  LVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYR 480

Query: 481  AQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQ 540
            AQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQ
Sbjct: 481  AQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQ 540

Query: 541  LDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSL 600
            LDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSL
Sbjct: 541  LDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSL 600

Query: 601  NVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADN 660
            NVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADN
Sbjct: 601  NVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADN 660

Query: 661  VLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCEL 720
            VLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCEL
Sbjct: 661  VLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCEL 720

Query: 721  GNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVE 780
            GNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVE
Sbjct: 721  GNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVE 780

Query: 781  LRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQP 840
            LRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQP
Sbjct: 781  LRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQP 840

Query: 841  SDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQP 900
            SDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQP
Sbjct: 841  SDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQP 900

Query: 901  SRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAW 960
            SRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAW
Sbjct: 901  SRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAW 960

Query: 961  FNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWK 1020
            FNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWK
Sbjct: 961  FNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWK 1020

Query: 1021 VGFFKRNRPPLEEDDEEGE 1039
            VGFFKRNRPPLEEDDEEGE
Sbjct: 1021 VGFFKRNRPPLEEDDEEGE 1039


>gi|49170034 integrin, alpha 8 [Homo sapiens]
          Length = 1063

 Score =  709 bits (1830), Expect = 0.0
 Identities = 421/1061 (39%), Positives = 599/1061 (56%), Gaps = 57/1061 (5%)

Query: 1    MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDS 60
            +A   C   AL +L W         +P   A NLD  +LT Y+GP GS FG+++DFH   
Sbjct: 17   IAPLCCAAAALGMLLW---------SPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPD 67

Query: 61   HGRVAIVVGAPR--TLGPSQEETGGVFLCPWRAEGG-QCPSLLFDLRD--ETRNVGSQTL 115
                +++VGAP+  T  P   E G V+ CPW AEG  QC  + FD  +  + R  G++  
Sbjct: 68   ARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKEP 127

Query: 116  QTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYS 175
              FK+ Q  GA+V +    +VACAP  HW  L+ T E  K PVG+C++A       AE+S
Sbjct: 128  IEFKSNQWFGATVKAHKGKVVACAPLYHWRTLKPTPE--KDPVGTCYVAIQNFSAYAEFS 185

Query: 176  PCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIF 235
            PCR +        N     + YC+AGFS    + G+L++G PG +Y+ G +  A VADI 
Sbjct: 186  PCRNS--------NADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADII 237

Query: 236  SSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTL 295
            ++Y    +L  ++ +  + + +   Y D Y GYSVA GEF GD +  E V G P  +   
Sbjct: 238  ANYSFKDILRKLAGEKQT-EVAPASYDDSYLGYSVAAGEFTGD-SQQELVAGIPRGAQNF 295

Query: 296  GAVEILDSYYQR-LHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLA 354
            G V I++S     +    GEQMASYFG++V V+DVN DG  D+LVGAPL+ME   +    
Sbjct: 296  GYVSIINSTDMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPR 355

Query: 355  EVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGP 414
            EVG++YL+LQ      L     +LTGT+ +GRFGSA+A LGDL++DGYNDIA+  P+ G 
Sbjct: 356  EVGQIYLYLQVSS--LLFRDPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGK 413

Query: 415  SGRGQVLVFLGQSEGLRSRPSQVLDSPFPTG---SAFGFSLRGAVDIDDNGYPDLIVGAY 471
              RG+VL++ G  +GL ++PSQVL   + +    S FGF+LRG  DID N YPDLIVGA+
Sbjct: 414  DQRGKVLIYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAF 473

Query: 472  GANQVAVYRAQPVVKASVQLLVQDSL-NPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIP 530
            G  +VAVYRA+PVV    QLL+   + N   K+C +P + T  +CF++++C   TG +I 
Sbjct: 474  GTGKVAVYRARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIA 533

Query: 531  QKLSLNAELQLDRQKPRQG-RRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADF 589
              + L AE+QLD  K +   +R L L + QA     L +  + S  C   + +LRDE +F
Sbjct: 534  NTIVLMAEVQLDSLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEF 593

Query: 590  RDKLSPIVLSLNVSLPPTE----AGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQL 645
            RDKLSPI +SLN SL  +       + P +  + +  V EQ  I++DCGED++CVP L+L
Sbjct: 594  RDKLSPINISLNYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKL 653

Query: 646  TASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLIC 705
            +A      +++G +N L L ++A NEGEGAYEAEL V +P+ A Y+    N +GF  L C
Sbjct: 654  SARPDKHQVIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSC 713

Query: 706  NQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSK 765
              K EN TR+V+C+LGNPM       + +  +V  LE+   S++F LQIRS N  NP+S 
Sbjct: 714  EYKMENVTRMVVCDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSN 773

Query: 766  IVLLDVPVRAEAQVELRGNSFPASLVVAAE--EGEREQNSLDSWGPKVEHTYELHNNGPG 823
             V L + + A AQVE+RG S P  +V+     E E E +  +  GP VEH YELHN GP 
Sbjct: 774  FVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPS 833

Query: 824  TVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPI--- 880
            T++   L +  P  ++   LLYI  IQ  G LQC P P +NP  +    P  SP      
Sbjct: 834  TISDTILEVGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIK---PAASPEDTPEL 890

Query: 881  ------HPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMV 934
                      H   +R + + E  + S  +   +++C +  C  + C +  +  G+ A++
Sbjct: 891  SAFLRNSTIPHLVRKRDVHVVEFHRQSPAK---ILNCTNIECLQISCAVGRLEGGESAVL 947

Query: 935  TVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALE--E 992
             V + LW  +  QR  D + L S   F V  +PY   P  LP G   + T ++ A     
Sbjct: 948  KVRSRLWAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVS 1007

Query: 993  RAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEE 1033
             +IP+W +++ +L GLL+L IL LA+WK GFF R RPP E+
Sbjct: 1008 FSIPLWVIILAILLGLLVLAILTLALWKCGFFDRARPPQED 1048


>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
          Length = 1049

 Score =  649 bits (1675), Expect = 0.0
 Identities = 404/1046 (38%), Positives = 577/1046 (55%), Gaps = 68/1046 (6%)

Query: 13   LLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPR 72
            LL  +LLLL P   P     NLD       +GP GS FGFS++F++     V+++VGAP+
Sbjct: 25   LLPLLLLLLPP--PPRVGGFNLDAEAPAVLSGPPGSFFGFSVEFYRPGTDGVSVLVGAPK 82

Query: 73   --TLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDE-------TRNVGSQTLQTFKARQG 123
              T  P   + G V+LCPW A   QC  + FD +         + + G + ++ +K+ Q 
Sbjct: 83   ANTSQPGVLQGGAVYLCPWGASPTQCTPIEFDSKGSRLLESSLSSSEGEEPVE-YKSLQW 141

Query: 124  LGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLS 183
             GA+V +    I+ACAP   W      +E    PVG+C+L+     R  EY+PCR     
Sbjct: 142  FGATVRAHGSSILACAPLYSWRT---EKEPLSDPVGTCYLSTDNFTRILEYAPCR----- 193

Query: 184  RIYVENDFSW--DKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPG 241
                 +DFSW   + YC+ GFS+  T+ G +VLG PG Y++ G +  A    I  SY P 
Sbjct: 194  -----SDFSWAAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIAESYYPE 248

Query: 242  ILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL 301
             L+  V  Q L    ++  Y D Y GYSVAVGEF GD +T ++V G P  + T G V IL
Sbjct: 249  YLINLVQGQ-LQTRQASSIYDDSYLGYSVAVGEFSGD-DTEDFVAGVPKGNLTYGYVTIL 306

Query: 302  D-SYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVY 360
            + S  + L+   GEQMASYFG++VA TDVNGDG  DLLVGAPL M+   D +  EVGRVY
Sbjct: 307  NGSDIRSLYNFSGEQMASYFGYAVAATDVNGDGLDDLLVGAPLLMDRTPDGRPQEVGRVY 366

Query: 361  LFLQPRGPHALG---APSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGR 417
            ++LQ    H  G    P+L LTG   +GRFGS++ PLGDLD+DGYND+A+ AP+GG + +
Sbjct: 367  VYLQ----HPAGIEPTPTLTLTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQ 422

Query: 418  GQVLVFLGQSEGLRSRPSQVLD---SPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGAN 474
            G V VF G   GL S+PSQVL    +   T   FG +LRG  D+D NGYPDLIVG++G +
Sbjct: 423  GVVFVFPGGPGGLGSKPSQVLQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVD 482

Query: 475  QVAVYRAQPVVKASVQLLVQDSL-NPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKL 533
            +  VYR +P+V AS  L +  ++ NP  +SC L     PV+C N+  C+ A+G ++   +
Sbjct: 483  KAVVYRGRPIVSASASLTIFPAMFNPEERSCSL--EGNPVACINLSFCLNASGKHVADSI 540

Query: 534  SLNAELQLDRQKPRQG-RRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDK 592
                ELQLD QK + G RR L L S+QA  T  L +       C     +LR+E++FRDK
Sbjct: 541  GFTVELQLDWQKQKGGVRRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRDK 600

Query: 593  LSPIVLSLNVSLPP----TEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTAS 648
            LSPI ++LN SL P       G+ PA+     + ++++ +I+LDCGED++CVP LQL   
Sbjct: 601  LSPIHIALNFSLDPQAPVDSHGLRPALHYQSKSRIEDKAQILLDCGEDNICVPDLQLEVF 660

Query: 649  VTGSPLLVGADNVLELQMDAANEGE-GAYEAELAVHLPQGAHYMRALSNVEGFERLICNQ 707
               + + +G  N L L   A N GE GAYEAEL V  P  A Y   + +   F  L C+ 
Sbjct: 661  GEQNHVYLGDKNALNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGLVRHPGNFSSLSCDY 720

Query: 708  KKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIV 767
               N++R+++C+LGNPMK  A +   +  +V +L +  +++ F  QI SKN  N  S +V
Sbjct: 721  FAVNQSRLLVCDLGNPMKAGASLWGGLRFTVPHLRDTKKTIQFDFQILSKNLNNSQSDVV 780

Query: 768  LLDVPVRAEAQVELRGNSFP-ASLVVAAEEGEREQ-NSLDSWGPKVEHTYELHNNGPGTV 825
               + V A+AQV L G S P A L   ++   R+Q    +  GP V H YEL N GP ++
Sbjct: 781  SFRLSVEAQAQVTLNGVSKPEAVLFPVSDWHPRDQPQKEEDLGPAVHHVYELINQGPSSI 840

Query: 826  NGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHH 885
            +   L +  P   +   LLY+  +    GL C    P+NP     GL +    P    HH
Sbjct: 841  SQGVLELSCPQALEGQQLLYVTRVT---GLNCTTNHPINPK----GLEL---DPEGSLHH 890

Query: 886  KRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSL 945
            ++ R       P + S    P ++ C  A C  ++C+L  + + +   + +   +W  + 
Sbjct: 891  QQKRE-----APSRSSASSGPQILKCPEAECFRLRCELGPLHQQESQSLQLHFRVWAKTF 945

Query: 946  YQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWT--QLLRALEERAIPIWWVLVG 1003
             QR    F LQ  A +    +PY + P  LP+ E QV T  Q  +A     +P+W +++ 
Sbjct: 946  LQREHQPFSLQCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLWIIILA 1005

Query: 1004 VLGGLLLLTILVLAMWKVGFFKRNRP 1029
            +L GLLLL +L+  ++K+GFFKR+ P
Sbjct: 1006 ILFGLLLLGLLIYILYKLGFFKRSLP 1031


>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
          Length = 1048

 Score =  630 bits (1624), Expect = e-180
 Identities = 399/1045 (38%), Positives = 569/1045 (54%), Gaps = 54/1045 (5%)

Query: 19   LLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDS-HGRVAIVVGAPR--TLG 75
            LLL     P   A NLD      Y+GP GS FGF++DF   S   R+ ++VGAP+  T  
Sbjct: 18   LLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQ 77

Query: 76   PSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVI 135
            P   E G V  C W +   +C  + FD            L+ FK+ Q  GASV S  D I
Sbjct: 78   PGIVEGGQVLKCDWSSTR-RCQPIEFDATGNRDYAKDDPLE-FKSHQWFGASVRSKQDKI 135

Query: 136  VACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDK 195
            +ACAP  HW    K E   + PVG+CFL   +  +  EY+PCR   +         +  +
Sbjct: 136  LACAPLYHWRTEMKQE---REPVGTCFLQ--DGTKTVEYAPCRSQDID--------ADGQ 182

Query: 196  RYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFD 255
             +C+ GFS   T+A  ++LG PG +Y+ G L    VA+I S Y P +     ++Q L+  
Sbjct: 183  GFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQ-LATR 241

Query: 256  SSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSY-YQRLHRLRGE 314
            ++   + D Y GYSVAVG+F+GD    ++V G P  + TLG V I D      L+   GE
Sbjct: 242  TAQAIFDDSYLGYSVAVGDFNGD-GIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE 300

Query: 315  QMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGA- 373
            QMA+YFG SVA TD+NGD   D+ +GAPL+M+  +D KL EVG+V + LQ     A G  
Sbjct: 301  QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQ----RASGDF 356

Query: 374  PSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSR 433
             +  L G +++ RFGSAIAPLGDLD+DG+NDIA+AAPYGG   +G V +F G+S GL + 
Sbjct: 357  QTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAV 416

Query: 434  PSQVLDSPFPTGS---AFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQ 490
            PSQ+L+  +   S   +FG+S++GA DID NGYPDLIVGA+G ++  +YRA+PV+  +  
Sbjct: 417  PSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAG 476

Query: 491  LLVQDS-LNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNI-PQKLSLNAELQLDRQKPRQ 548
            L V  S LN   K+C LP T   VSCFN++ C+ A G  + P+KL+   EL LD+ K + 
Sbjct: 477  LEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKG 536

Query: 549  G-RRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPT 607
              RR L L S+    + N+ +       C   +A+LRDE++FRDKL+PI + +   L   
Sbjct: 537  AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYR 596

Query: 608  EA----GMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLE 663
             A    G+ P +      ++  Q  I+LDCGED+VC P+L+++       + +G DN L 
Sbjct: 597  TAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLT 656

Query: 664  LQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNP 723
            L + A N+GEGAYEAEL V +P  A ++  + N E   RL C  K EN+TR V+C+LGNP
Sbjct: 657  LIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNP 716

Query: 724  MKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRG 783
            MK   Q+   +  SV    E   SV F LQI+S N  +  S +V   V +   A VE+RG
Sbjct: 717  MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRG 776

Query: 784  NSFPASLVVAAEEGEREQN--SLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPS 841
             S P  + +     E ++N  + +  GP V+H YEL NNGP + +   L +  P +   +
Sbjct: 777  VSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNN 836

Query: 842  DLLYILDIQPQGGLQCFPQPPVNPLKVD-WGLPIPSPSPIHPAHHKRD----RRQIFLPE 896
             LLYIL     G + C     +NPL++    L     +       +RD    +R + L E
Sbjct: 837  TLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSE 896

Query: 897  PEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLD--QFV 954
                    D   + C  A C  + C +  + RG+ A++ V + LW  +   +      + 
Sbjct: 897  -------GDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYS 949

Query: 955  LQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALE--ERAIPIWWVLVGVLGGLLLLT 1012
            L+S A FNV   PY   P+        V T +   ++     +P+W +++ VL GLLLL 
Sbjct: 950  LKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLA 1009

Query: 1013 ILVLAMWKVGFFKRNRPPLEEDDEE 1037
            +LV  M+++GFFKR RPP EE + E
Sbjct: 1010 VLVFVMYRMGFFKRVRPPQEEQERE 1034


>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
          Length = 1002

 Score =  604 bits (1558), Expect = e-172
 Identities = 380/1000 (38%), Positives = 547/1000 (54%), Gaps = 53/1000 (5%)

Query: 63   RVAIVVGAPR--TLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKA 120
            R+ ++VGAP+  T  P   E G V  C W +   +C  + FD            L+ FK+
Sbjct: 17   RMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTR-RCQPIEFDATGNRDYAKDDPLE-FKS 74

Query: 121  RQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGN 180
             Q  GASV S  D I+ACAP  HW    K E   + PVG+CFL   +  +  EY+PCR  
Sbjct: 75   HQWFGASVRSKQDKILACAPLYHWRTEMKQE---REPVGTCFLQ--DGTKTVEYAPCRSQ 129

Query: 181  TLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRP 240
             +         +  + +C+ GFS   T+A  ++LG PG +Y+ G L    VA+I S Y P
Sbjct: 130  DID--------ADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDP 181

Query: 241  GILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEI 300
             +     ++Q L+  ++   + D Y GYSVAVG+F+GD    ++V G P  + TLG V I
Sbjct: 182  NVYSIKYNNQ-LATRTAQAIFDDSYLGYSVAVGDFNGD-GIDDFVSGVPRAARTLGMVYI 239

Query: 301  LDSY-YQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRV 359
             D      L+   GEQMA+YFG SVA TD+NGD   D+ +GAPL+M+  +D KL EVG+V
Sbjct: 240  YDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQV 299

Query: 360  YLFLQPRGPHALGA-PSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRG 418
             + LQ     A G   +  L G +++ RFGSAIAPLGDLD+DG+NDIA+AAPYGG   +G
Sbjct: 300  SVSLQ----RASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKG 355

Query: 419  QVLVFLGQSEGLRSRPSQVLDSPFPTGS---AFGFSLRGAVDIDDNGYPDLIVGAYGANQ 475
             V +F G+S GL + PSQ+L+  +   S   +FG+S++GA DID NGYPDLIVGA+G ++
Sbjct: 356  IVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDR 415

Query: 476  VAVYRAQPVVKASVQLLVQDS-LNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNI-PQKL 533
              +YRA+PV+  +  L V  S LN   K+C LP T   VSCFN++ C+ A G  + P+KL
Sbjct: 416  AILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKL 475

Query: 534  SLNAELQLDRQKPRQG-RRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDK 592
            +   EL LD+ K +   RR L L S+    + N+ +       C   +A+LRDE++FRDK
Sbjct: 476  NFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDK 535

Query: 593  LSPIVLSLNVSLPPTEA----GMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTAS 648
            L+PI + +   L    A    G+ P +      ++  Q  I+LDCGED+VC P+L+++  
Sbjct: 536  LTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD 595

Query: 649  VTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQK 708
                 + +G DN L L + A N+GEGAYEAEL V +P  A ++  + N E   RL C  K
Sbjct: 596  SDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFK 655

Query: 709  KENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVL 768
             EN+TR V+C+LGNPMK   Q+   +  SV    E   SV F LQI+S N  +  S +V 
Sbjct: 656  TENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVS 715

Query: 769  LDVPVRAEAQVELRGNSFPASLVVAAEEGEREQN--SLDSWGPKVEHTYELHNNGPGTVN 826
              V +   A VE+RG S P  + +     E ++N  + +  GP V+H YEL NNGP + +
Sbjct: 716  HKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFS 775

Query: 827  GLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVD-WGLPIPSPSPIHPAHH 885
               L +  P +   + LLYIL     G + C     +NPL++    L     +       
Sbjct: 776  KAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQG 835

Query: 886  KRD----RRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLW 941
            +RD    +R + L E        D   + C  A C  + C +  + RG+ A++ V + LW
Sbjct: 836  ERDHLITKRDLALSE-------GDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLW 888

Query: 942  LPSLYQRPLD--QFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALE--ERAIPI 997
              +   +      + L+S A FNV   PY   P+        V T +   ++     +P+
Sbjct: 889  TETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPV 948

Query: 998  WWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEE 1037
            W +++ VL GLLLL +LV  M+++GFFKR RPP EE + E
Sbjct: 949  WVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQERE 988


>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
          Length = 1012

 Score =  590 bits (1520), Expect = e-168
 Identities = 387/1045 (37%), Positives = 547/1045 (52%), Gaps = 90/1045 (8%)

Query: 19   LLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDS-HGRVAIVVGAPR--TLG 75
            LLL     P   A NLD      Y+GP GS FGF++DF   S   R+ ++VGAP+  T  
Sbjct: 18   LLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQ 77

Query: 76   PSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVI 135
            P   E G V  C W +   +C  + FD            L+ FK+ Q  GASV S  D I
Sbjct: 78   PGIVEGGQVLKCDWSSTR-RCQPIEFDATGNRDYAKDDPLE-FKSHQWFGASVRSKQDKI 135

Query: 136  VACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDK 195
            +ACAP  HW    K E   + PVG+CFL   +  +  EY+PCR   L             
Sbjct: 136  LACAPLYHWRTEMKQE---REPVGTCFLQ--DGTKTVEYAPCRSRQL------------- 177

Query: 196  RYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFD 255
                                               VA+I S Y P +     ++Q L+  
Sbjct: 178  -------------------------------ISDQVAEIVSKYDPNVYSIKYNNQ-LATR 205

Query: 256  SSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSY-YQRLHRLRGE 314
            ++   + D Y GYSVAVG+F+GD    ++V G P  + TLG V I D      L+   GE
Sbjct: 206  TAQAIFDDSYLGYSVAVGDFNGD-GIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE 264

Query: 315  QMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGA- 373
            QMA+YFG SVA TD+NGD   D+ +GAPL+M+  +D KL EVG+V + LQ     A G  
Sbjct: 265  QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQ----RASGDF 320

Query: 374  PSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSR 433
             +  L G +++ RFGSAIAPLGDLD+DG+NDIA+AAPYGG   +G V +F G+S GL + 
Sbjct: 321  QTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAV 380

Query: 434  PSQVLDSPFPTGS---AFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQ 490
            PSQ+L+  +   S   +FG+S++GA DID NGYPDLIVGA+G ++  +YRA+PV+  +  
Sbjct: 381  PSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAG 440

Query: 491  LLVQDS-LNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNI-PQKLSLNAELQLDRQKPRQ 548
            L V  S LN   K+C LP T   VSCFN++ C+ A G  + P+KL+   EL LD+ K + 
Sbjct: 441  LEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKG 500

Query: 549  G-RRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPT 607
              RR L L S+    + N+ +       C   +A+LRDE++FRDKL+PI + +   L   
Sbjct: 501  AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYR 560

Query: 608  EA----GMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLE 663
             A    G+ P +      ++  Q  I+LDCGED+VC P+L+++       + +G DN L 
Sbjct: 561  TAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLT 620

Query: 664  LQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNP 723
            L + A N+GEGAYEAEL V +P  A ++  + N E   RL C  K EN+TR V+C+LGNP
Sbjct: 621  LIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNP 680

Query: 724  MKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRG 783
            MK   Q+   +  SV    E   SV F LQI+S N  +  S +V   V +   A VE+RG
Sbjct: 681  MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRG 740

Query: 784  NSFPASLVVAAEEGEREQN--SLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPS 841
             S P  + +     E ++N  + +  GP V+H YEL NNGP + +   L +  P +   +
Sbjct: 741  VSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNN 800

Query: 842  DLLYILDIQPQGGLQCFPQPPVNPLKVD-WGLPIPSPSPIHPAHHKRD----RRQIFLPE 896
             LLYIL     G + C     +NPL++    L     +       +RD    +R + L E
Sbjct: 801  TLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSE 860

Query: 897  PEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLD--QFV 954
                    D   + C  A C  + C +  + RG+ A++ V + LW  +   +      + 
Sbjct: 861  -------GDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYS 913

Query: 955  LQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALE--ERAIPIWWVLVGVLGGLLLLT 1012
            L+S A FNV   PY   P+        V T +   ++     +P+W +++ VL GLLLL 
Sbjct: 914  LKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLA 973

Query: 1013 ILVLAMWKVGFFKRNRPPLEEDDEE 1037
            +LV  M+++GFFKR RPP EE + E
Sbjct: 974  VLVFVMYRMGFFKRVRPPQEEQERE 998


>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
          Length = 1137

 Score =  287 bits (734), Expect = 4e-77
 Identities = 318/1106 (28%), Positives = 495/1106 (44%), Gaps = 169/1106 (15%)

Query: 29   AWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVA--IVVGAPRTL---GPSQEETGG 83
            A A NLD +      G  GS FGFS+  H+    R    ++VGAP+ L   G     TGG
Sbjct: 31   AVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGG 90

Query: 84   VFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSD--VIVACAPW 141
            +F CP   E   C  +  D        G+   +  K  Q LG SV S      IV CA  
Sbjct: 91   LFACPLSLEETDCYRVDIDQ-------GADMQKESKENQWLGVSVRSQGPGGKIVTCA-- 141

Query: 142  QHWNVLEKTEEAEKTP--VGSCFLAQPESGRR-----AEYSPCRGNTLSRIYVENDFSWD 194
              +   ++ ++  +T   +G CF+   +   R      E+  C G    R      F + 
Sbjct: 142  HRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEG----RPQGHEQFGFC 197

Query: 195  KRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSF 254
            ++   A FS     +  L+ GAPG Y + GLL    V +I SS    ++   +       
Sbjct: 198  QQGTAAAFSP---DSHYLLFGAPGTYNWKGLLF---VTNIDSSDPDQLVYKTLDPADRLP 251

Query: 255  DSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL--DSYYQRLHR-- 310
              +     + Y G+S+  G+         +V GAP  +   GAV IL  DS  + +    
Sbjct: 252  GPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHK-GAVVILRKDSASRLVPEVM 310

Query: 311  LRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHA 370
            L GE++ S FG+S+AV D+N DG  DL+VGAP + E + +      G VY++L  +G H 
Sbjct: 311  LSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELG----GAVYVYLN-QGGHW 365

Query: 371  LGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGL 430
             G   L L G+     FG ++A LGDL++DG+ DIAV AP+ G    G+V ++ G S G+
Sbjct: 366  AGISPLRLCGSP-DSMFGISLAVLGDLNQDGFPDIAVGAPFDGD---GKVFIYHGSSLGV 421

Query: 431  RSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQ 490
             ++PSQVL+       +FG+SL G++D+D N YPDL+VG+  A+   ++RA+P++  S +
Sbjct: 422  VAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPILHVSHE 480

Query: 491  LLVQDSLNPAVKSCVLPQTKTPVS---CFNIQMCVG--ATGHNIPQKLSLNAELQLDRQK 545
            + +      A +S  L Q         C ++++C    A   +    ++L+  L  D  +
Sbjct: 481  VSI------APRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDR 534

Query: 546  PRQGR--RVLLLG-------SQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPI 596
              +G+  RV  L         Q +GT     L  +H  +C   M  L++  + +DKL  I
Sbjct: 535  RLRGQVPRVTFLSRNLEEPKHQASGTVW---LKHQHDRVCGDAMFQLQE--NVKDKLRAI 589

Query: 597  VLSLNVSL-PPTEAGMAP-------AVVLHGDTHVQEQTRIVL---DCGEDDVCVPQLQL 645
            V++L+ SL  P     AP       A +L+      ++  I      CGED +C   LQL
Sbjct: 590  VVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQL 649

Query: 646  TA--------------------------SVTGSPLLVGADNVLELQMDAAN---EGEGAY 676
                                        +++G P++     V  L  D A    +G+ A+
Sbjct: 650  VRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAH 709

Query: 677  EAELAVHLPQGAHY--MRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAM 734
            EA+L V LP   HY  +RAL   +  E+ +C    EN + V  CELGNPMK+ AQ+   +
Sbjct: 710  EAQLLVMLPDSLHYSGVRAL---DPAEKPLC-LSNENASHVE-CELGNPMKRGAQVTFYL 764

Query: 735  LVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVEL----RGNSFPASL 790
            ++S   +      +  +L + + + Q       L  V  RA   +EL     G + P  L
Sbjct: 765  ILSTSGISIETTELEVELLLATISEQE------LHPVSARARVFIELPLSIAGMAIPQQL 818

Query: 791  VVA-AEEGEREQNSLDSWGPKVEHTYELHNNGPG--TVNGLHLSIHLPGQ-SQPSDLLYI 846
              +    GER   S    G KV++   + N G    T+    L+I  P + +    LLY 
Sbjct: 819  FFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYP 878

Query: 847  LDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFL--PEPEQPSRLQ 904
            + ++ +GG     Q P        GL  P P+ +H     RDRR+  L  PE ++P   Q
Sbjct: 879  MQVELEGG-----QGPGQK-----GLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQ 928

Query: 905  DP---------------VLVSC--DSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQ 947
            +P               + + C   +A C V  C L    R   A++ V   LW  +  +
Sbjct: 929  EPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRA--AVLHVWGRLWNSTFLE 986

Query: 948  RPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLL---RALEERAIPIWWVLVGV 1004
                   L+     N+ ++  ++  L L      +   +     A+    +P W +L+ V
Sbjct: 987  EYSAVKSLEVIVRANI-TVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAV 1045

Query: 1005 LGGLLLLTILVLAMWKVGFFKRNRPP 1030
            L GLL+L +LVL +WK+GFFKR + P
Sbjct: 1046 LAGLLVLALLVLLLWKMGFFKRAKHP 1071


>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
          Length = 1141

 Score =  282 bits (721), Expect = 1e-75
 Identities = 317/1111 (28%), Positives = 492/1111 (44%), Gaps = 175/1111 (15%)

Query: 29   AWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVA--IVVGAPRTL---GPSQEETGG 83
            A A NLD +      G  GS FGFS+  H+    R    ++VGAP+ L   G     TGG
Sbjct: 31   AVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGG 90

Query: 84   VFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSD--VIVACAPW 141
            +F CP   E   C  +  D        G+   +  K  Q LG SV S      IV CA  
Sbjct: 91   LFACPLSLEETDCYRVDIDQ-------GADMQKESKENQWLGVSVRSQGPGGKIVTCA-- 141

Query: 142  QHWNVLEKTEEAEKTP--VGSCFLAQPESGRR-----AEYSPCRGNTLSRIYVENDFSWD 194
              +   ++ ++  +T   +G CF+   +   R      E+  C G    R      F + 
Sbjct: 142  HRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEG----RPQGHEQFGFC 197

Query: 195  KRYCEAGFSSVVTQAGELVLGAPGGYYFLG-----LLAQAPVADIFSSYRPGILLWHVSS 249
            ++   A FS     +  L+ GAPG Y + G     L AQ           P    +    
Sbjct: 198  QQGTAAAFSP---DSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGP----YEAGG 250

Query: 250  QSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL--DSYYQR 307
            +        P   + Y+G+S+  G+         +V GAP  +   GAV IL  DS  + 
Sbjct: 251  EKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHK-GAVVILRKDSASRL 309

Query: 308  LHR--LRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQP 365
            +    L GE++ S FG+S+AV D+N DG  DL+VGAP + E + +      G VY++L  
Sbjct: 310  VPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELG----GAVYVYLN- 364

Query: 366  RGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLG 425
            +G H  G   L L G+     FG ++A LGDL++DG+ DIAV AP+ G    G+V ++ G
Sbjct: 365  QGGHWAGISPLRLCGSP-DSMFGISLAVLGDLNQDGFPDIAVGAPFDGD---GKVFIYHG 420

Query: 426  QSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVV 485
             S G+ ++PSQVL+       +FG+SL G++D+D N YPDL+VG+  A+   ++RA+P++
Sbjct: 421  SSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPIL 479

Query: 486  KASVQLLVQDSLNPAVKSCVLPQTKTPVS---CFNIQMCVG--ATGHNIPQKLSLNAELQ 540
              S ++ +      A +S  L Q         C ++++C    A   +    ++L+  L 
Sbjct: 480  HVSHEVSI------APRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLD 533

Query: 541  LDRQKPRQGR--RVLLLG-------SQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRD 591
             D  +  +G+  RV  L         Q +GT     L  +H  +C   M  L++  + +D
Sbjct: 534  ADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVW---LKHQHDRVCGDAMFQLQE--NVKD 588

Query: 592  KLSPIVLSLNVSL-PPTEAGMAP-------AVVLHGDTHVQEQTRIVL---DCGEDDVCV 640
            KL  IV++L+ SL  P     AP       A +L+      ++  I      CGED +C 
Sbjct: 589  KLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQ 648

Query: 641  PQLQLTA--------------------------SVTGSPLLVGADNVLELQMDAAN---E 671
              LQL                            +++G P++     V  L  D A    +
Sbjct: 649  SNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQAD 708

Query: 672  GEGAYEAELAVHLPQGAHY--MRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQ 729
            G+ A+EA+L V LP   HY  +RAL   +  E+ +C    EN + V  CELGNPMK+ AQ
Sbjct: 709  GDDAHEAQLLVMLPDSLHYSGVRAL---DPAEKPLC-LSNENASHVE-CELGNPMKRGAQ 763

Query: 730  IGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVEL----RGNS 785
            +   +++S   +      +  +L + + + Q       L  V  RA   +EL     G +
Sbjct: 764  VTFYLILSTSGISIETTELEVELLLATISEQE------LHPVSARARVFIELPLSIAGMA 817

Query: 786  FPASLVVA-AEEGEREQNSLDSWGPKVEHTYELHNNGPG--TVNGLHLSIHLPGQ-SQPS 841
             P  L  +    GER   S    G KV++   + N G    T+    L+I  P + +   
Sbjct: 818  IPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGK 877

Query: 842  DLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFL--PEPEQ 899
             LLY + ++ +GG     Q P        GL  P P+ +H     RDRR+  L  PE ++
Sbjct: 878  WLLYPMQVELEGG-----QGPGQK-----GLCSPRPNILHLDVDSRDRRRRELEPPEQQE 927

Query: 900  PSRLQDP---------------VLVSC--DSAPCTVVQCDLQEMARGQRAMVTVLAFLWL 942
            P   Q+P               + + C   +A C V  C L    R   A++ V   LW 
Sbjct: 928  PGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRA--AVLHVWGRLWN 985

Query: 943  PSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLL---RALEERAIPIWW 999
             +  +       L+     N+ ++  ++  L L      +   +     A+    +P W 
Sbjct: 986  STFLEEYSAVKSLEVIVRANI-TVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWV 1044

Query: 1000 VLVGVLGGLLLLTILVLAMWKVGFFKRNRPP 1030
            +L+ VL GLL+L +LVL +WK+GFFKR + P
Sbjct: 1045 ILLAVLAGLLVLALLVLLLWKMGFFKRAKHP 1075


>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
          Length = 1051

 Score =  269 bits (687), Expect = 1e-71
 Identities = 303/1074 (28%), Positives = 466/1074 (43%), Gaps = 158/1074 (14%)

Query: 31   ALNLDPVQLTFY-AGPNGSQFGFSLDFHKDSHG--RVAIVVGAPRTLGPSQ---EETGGV 84
            A NLD   L    AG  GS FG+S+  H+ +    R  ++ GAPR L         TG V
Sbjct: 32   AFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRYLLLAGAPRELAVPDGYTNRTGAV 91

Query: 85   FLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDV--IVACAPWQ 142
            +LCP  A    C  +   ++++    G   ++       LG +V S      ++ CA  +
Sbjct: 92   YLCPLTAHKDDCERMNITVKNDP---GHHIIEDM----WLGVTVASQGPAGRVLVCAH-R 143

Query: 143  HWNVLEKTEEAEKTPVGSCF-------LAQPESGRRAEYSPCRGNTLSRIYVENDFSWDK 195
            +  VL    E ++  VG C+       L   +  +      C  NT    Y+E       
Sbjct: 144  YTQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTYHNEMCNSNT---DYLETGM---- 196

Query: 196  RYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFD 255
              C+ G S   TQ   +  GAPG Y + G           +SY      W +S  S    
Sbjct: 197  --CQLGTSGGFTQ-NTVYFGAPGAYNWKG-----------NSYMIQRKEWDLSEYSYKDP 242

Query: 256  SSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSY----YQRLHRL 311
                     Y GY++ VG F         V GAP     +GAV +L        +R   L
Sbjct: 243  EDQGNL---YIGYTMQVGSFILHPKNITIVTGAPRHRH-MGAVFLLSQEAGGDLRRRQVL 298

Query: 312  RGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHAL 371
             G Q+ +YFG ++A+ D+N DG  DLLVGAP Y E    RK    G +Y+F+   G    
Sbjct: 299  EGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFE----RKEEVGGAIYVFMNQAGTSFP 354

Query: 372  GAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLR 431
              PSLLL G      FG ++A +GD+++DG+ DIAV AP+    G G+V ++   S+GL 
Sbjct: 355  AHPSLLLHGPS-GSAFGLSVASIGDINQDGFQDIAVGAPF---EGLGKVYIYHSSSKGLL 410

Query: 432  SRPSQVLDSP---FPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKAS 488
             +P QV+       P  + FG+SL G +D+D+N YPDL+VG+  ++ + + RA+PV+   
Sbjct: 411  RQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSL-SDHIVLLRARPVINIV 469

Query: 489  VQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCV----GATGHNIPQKLSLNAELQLDRQ 544
             + LV     PAV     P   T  SC  +++C      A   N  + ++L   L+ DR 
Sbjct: 470  HKTLVP---RPAVLD---PALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRD 523

Query: 545  KPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSL 604
              R+  R+   GS+ A   +           C      L D  + RDKL PI++S+N SL
Sbjct: 524  --RRPPRLRFAGSESA---VFHGFFSMPEMRCQKLELLLMD--NLRDKLRPIIISMNYSL 576

Query: 605  P---PTEAGMA-----------PAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVT 650
            P   P    +             A  L   T VQ Q     +CG D+ C   LQ+ A+  
Sbjct: 577  PLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQK----ECGPDNKCESNLQMRAAFV 632

Query: 651  G------SPLLVGAD-NVLELQMDAAN------EGEGAYEAELAVHLPQGAHYMRALSNV 697
                   S L    D   L L ++  N       GE A+EA L + +P        LS+V
Sbjct: 633  SEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPAL----LLSSV 688

Query: 698  EGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSK 757
                       + NET  + CELGNP K+N ++ + +   V  +      +  QLQ+ + 
Sbjct: 689  RP-----PGACQANET--IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTS 741

Query: 758  NSQN---PNSKIVLLDVPVRAE-AQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEH 813
            + Q+   P    +L+D  ++   + V  R  SF    V+    GE    +++  G  +++
Sbjct: 742  SHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVM----GESGMKTVEDVGSPLKY 797

Query: 814  TYELHNNGPGTV--NGLHLSIHLPGQ-SQPSDLLYILDIQPQGGLQCFPQPP---VNPLK 867
             +++   G G V    L L +  P + S    LLY  +I   G      +PP   +NPL 
Sbjct: 798  EFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLN 857

Query: 868  VDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQP--------SRLQDPVLVSCDS--APCT 917
            +   L  P   P  P   +R RRQ+     + P         + +   +++C +  A C 
Sbjct: 858  LT--LSDPGDRPSSP---QRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCV 912

Query: 918  VVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPR 977
             ++C + +        VTV A +W  +  +   D   ++ + W  +  L  ++P +++  
Sbjct: 913  WLECPIPDAP--VVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATL-FLRTSIPTINMEN 969

Query: 978  GEAQVWTQLLRALEER---AIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNR 1028
                    +   L E     I +W VLV V  GLLLL +++L +WK GFFKR R
Sbjct: 970  KTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRAR 1023


>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
          Length = 1066

 Score =  267 bits (682), Expect = 4e-71
 Identities = 302/1074 (28%), Positives = 465/1074 (43%), Gaps = 158/1074 (14%)

Query: 31   ALNLDPVQLTFY-AGPNGSQFGFSLDFHKDSHG--RVAIVVGAPRTLGPSQ---EETGGV 84
            A NLD   L    AG  GS FG+S+  H+ +    R  ++ GAPR L         TG V
Sbjct: 32   AFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRYLLLAGAPRELAVPDGYTNRTGAV 91

Query: 85   FLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDV--IVACAPWQ 142
            +LCP  A    C  +   ++++    G   ++       LG +V S      ++ CA  +
Sbjct: 92   YLCPLTAHKDDCERMNITVKNDP---GHHIIEDM----WLGVTVASQGPAGRVLVCAH-R 143

Query: 143  HWNVLEKTEEAEKTPVGSCF-------LAQPESGRRAEYSPCRGNTLSRIYVENDFSWDK 195
            +  VL    E ++  VG C+       L   +  +      C  NT    Y+E       
Sbjct: 144  YTQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTYHNEMCNSNT---DYLETGM---- 196

Query: 196  RYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFD 255
              C+ G S   TQ   +  GAPG Y + G           +SY      W +S  S    
Sbjct: 197  --CQLGTSGGFTQ-NTVYFGAPGAYNWKG-----------NSYMIQRKEWDLSEYSYKDP 242

Query: 256  SSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSY----YQRLHRL 311
                     Y GY++ VG F         V GAP     +GAV +L        +R   L
Sbjct: 243  EDQGNL---YIGYTMQVGSFILHPKNITIVTGAPRHRH-MGAVFLLSQEAGGDLRRRQVL 298

Query: 312  RGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHAL 371
             G Q+ +YFG ++A+ D+N DG  DLLVGAP Y E    RK    G +Y+F+   G    
Sbjct: 299  EGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFE----RKEEVGGAIYVFMNQAGTSFP 354

Query: 372  GAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLR 431
              PSLLL G      FG ++A +GD+++DG+ DIAV AP+    G G+V ++   S+GL 
Sbjct: 355  AHPSLLLHGPS-GSAFGLSVASIGDINQDGFQDIAVGAPF---EGLGKVYIYHSSSKGLL 410

Query: 432  SRPSQVLDSP---FPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKAS 488
             +P QV+       P  + FG+SL G +D+D+N YPDL+VG+  ++ + + RA+PV+   
Sbjct: 411  RQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSL-SDHIVLLRARPVINIV 469

Query: 489  VQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCV----GATGHNIPQKLSLNAELQLDRQ 544
             + LV     PAV     P   T  SC  +++C      A   N  + ++L   L+ DR 
Sbjct: 470  HKTLVP---RPAVLD---PALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRD 523

Query: 545  KPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSL 604
              R+  R+   GS+ A   +           C      L D  + RDKL PI++S+N SL
Sbjct: 524  --RRPPRLRFAGSESA---VFHGFFSMPEMRCQKLELLLMD--NLRDKLRPIIISMNYSL 576

Query: 605  P---PTEAGMA-----------PAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVT 650
            P   P    +             A  L   T VQ Q     +CG D+ C   LQ+ A+  
Sbjct: 577  PLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQK----ECGPDNKCESNLQMRAAFV 632

Query: 651  G------SPLLVGAD-NVLELQMDAAN------EGEGAYEAELAVHLPQGAHYMRALSNV 697
                   S L    D   L L ++  N       GE A+EA L + +P        LS+V
Sbjct: 633  SEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPAL----LLSSV 688

Query: 698  EGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSK 757
                       + NET  + CELGNP K+N ++ + +   V  +      +  QLQ+ + 
Sbjct: 689  RP-----PGACQANET--IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTS 741

Query: 758  NSQN---PNSKIVLLDVPVRAE-AQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEH 813
            + Q+   P    +L+D  ++   + V  R  SF    V+    GE    +++  G  +++
Sbjct: 742  SHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVM----GESGMKTVEDVGSPLKY 797

Query: 814  TYELHNNGPGTV--NGLHLSIHLPGQ-SQPSDLLYILDIQPQGGLQCFPQPP---VNPLK 867
             +++   G G V    L L +  P + S    LLY  +I   G      +PP   +NPL 
Sbjct: 798  EFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLN 857

Query: 868  VDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQP--------SRLQDPVLVSCDS--APCT 917
            +   L  P   P  P   +R RRQ+     + P         + +   +++C +  A C 
Sbjct: 858  LT--LSDPGDRPSSP---QRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCV 912

Query: 918  VVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPR 977
             ++C + +        VTV A +W  +  +   D   ++ + W  +  L  ++P +++  
Sbjct: 913  WLECPIPDAP--VVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATL-FLRTSIPTINMEN 969

Query: 978  GEAQVWTQLLRALEER---AIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNR 1028
                    +   L E     I +W VLV V  GLLLL +++L +WK  FFKR R
Sbjct: 970  KTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCDFFKRTR 1023


>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
          Length = 1035

 Score =  249 bits (636), Expect = 1e-65
 Identities = 269/1076 (25%), Positives = 460/1076 (42%), Gaps = 129/1076 (11%)

Query: 18   LLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRT---L 74
            LLL    A  PA A NLDP +   + GP  S FG+++  H   + R  ++VGAP+     
Sbjct: 16   LLLALVVAGIPAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRW-VLVGAPKADSKY 74

Query: 75   GPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVG-SQTLQTFKARQGLGASVVSWSD 133
             PS +  G VF C       +  + L   R + R     +T +  +  + +G S+     
Sbjct: 75   SPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMGVSLARQPK 134

Query: 134  V---IVACAPWQHW-NVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVEN 189
                ++ACA    W N+  + +     P G C++              +G TL   Y E 
Sbjct: 135  ADGRVLACA--HRWKNIYYEADHI--LPHGFCYIIPSNL-------QAKGRTLIPCYEEY 183

Query: 190  DFSWDKRY--CEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVAD-IFSSYRPGILLWH 246
               + + +  C+AG +   T+   +V+GAPG +Y+ G +    + D  +      +++  
Sbjct: 184  KKKYGEEHGSCQAGIAGFFTEE-LVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEVIM-- 240

Query: 247  VSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQ 306
                       N  Y   Y GY+V  G F    +T + V GAP     +G V I  +  +
Sbjct: 241  -----------NRRYT--YLGYAVTAGHFSHP-STIDVVGGAPQ-DKGIGKVYIFRADRR 285

Query: 307  -----RLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYL 361
                 ++ +  G++M SYFG S+   D+NGDG  DLLVGAP++ E R +      G+V +
Sbjct: 286  SGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDE------GQVTV 339

Query: 362  FLQPRGPHALGAPSLLLTGTQLYG-RFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQV 420
            ++  RG  AL    L LTG   Y   FG +IA L DLD DG+ D+A+ AP       G V
Sbjct: 340  YIN-RGNGAL-EEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFA-GAV 396

Query: 421  LVFLGQSEGLRSRPSQVLDSPF--PTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAV 478
             ++ G + G+  + S  L      P    FG S+ G +D+D NGYPD+ VGA+ ++ V +
Sbjct: 397  YIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVL 456

Query: 479  YRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAE 538
             RA+PV+   V + +  S+N     C     + PV+C N+  C    G ++P ++ LN  
Sbjct: 457  LRARPVITVDVSIFLPGSINITAPQC--HDGQQPVNCLNVTTCFSFHGKHVPGEIGLNYV 514

Query: 539  LQLDRQKPRQGRR----VLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLS 594
            L  D  K  +G+      +LLG      T  L L       C   +A ++     +D +S
Sbjct: 515  LMADVAKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEE-TCRHYVAHVKRRV--QDVIS 571

Query: 595  PIVLSLNVSLPPTEAG--------MAPAVVLHGDTHVQEQTRIVLD--CGEDDVCVPQLQ 644
            PIV     SL     G        + P +       + ++ + V +  C  +D C   LQ
Sbjct: 572  PIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSED-CAADLQ 630

Query: 645  LTASVTGSP-------LLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNV 697
            L   +  S        L +GA   + L +  +N G+ AY+A ++ ++ +   ++      
Sbjct: 631  LQGKLLLSSMDEKTLYLALGAVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQKE 690

Query: 698  EGFERLICNQKKENETRVVLCELGNP-MKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRS 756
            E    + C      E+  + C +G P M+  ++   +++    +L    E +SF +  +S
Sbjct: 691  E--MGISCELL---ESDFLKCSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQS 745

Query: 757  KNSQNPNS---KIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGER---EQNSLDSWGPK 810
             N++   S     ++L VP+  E    + G   P S V           + + L+     
Sbjct: 746  GNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQP 805

Query: 811  VEHTYELHNNGPGTVNGLHLSIHLPGQ--SQPSDLLYILDI---QPQG--GLQCFPQPPV 863
            +  T +++N GP T+ G  +SI  P +  S  +++ ++ ++   Q +G    Q  P P +
Sbjct: 806  INITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCI 865

Query: 864  NPLKVDWGLPIPSPSPIHP--AHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQC 921
                    +P    +  H   A   +  R++   + E+P               C    C
Sbjct: 866  --------IPQEQENIFHTIFAFFTKSGRKVL--DCEKP------------GISCLTAHC 903

Query: 922  DLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQ 981
            +   +A+ +   + +   L    L +         S A   V      V        E  
Sbjct: 904  NFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGNPEEVT 963

Query: 982  VWTQLLRALEERAIPIWWVL-VGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDE 1036
            V  + L  LE R   + W++ + +L G+L+  +L + +WK+GFF+R    + E ++
Sbjct: 964  VVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEAEK 1019


>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
          Length = 1032

 Score =  248 bits (633), Expect = 2e-65
 Identities = 285/1086 (26%), Positives = 458/1086 (42%), Gaps = 152/1086 (13%)

Query: 15   EWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVA-IVVGAPRT 73
            E V+LLL     P     N+D      Y GP+ + FG+S+  H  SHG    ++VGAP  
Sbjct: 18   ETVMLLLC-LGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLH--SHGANRWLLVGAPTA 74

Query: 74   ---LGPSQEETGGVFLCPWRAEGGQ-CPSLLFDLRDETRNVGSQTLQTFKARQGLGASVV 129
                  S    G ++ C      GQ C  L   L         +T    +  Q LG ++ 
Sbjct: 75   NWLANASVINPGAIYRCRIGKNPGQTCEQL--QLGSPNGEPCGKTCLEERDNQWLGVTLS 132

Query: 130  SW---SDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYS----PCRGNTL 182
                 +  IV C     W  +   +   K P G C+   P+   R E S    PC  + +
Sbjct: 133  RQPGENGSIVTCG--HRWKNIFYIKNENKLPTGGCYGVPPDL--RTELSKRIAPCYQDYV 188

Query: 183  SRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGI 242
             + + EN  S     C+AG SS  T+   +V+GAPG  Y+ G L    V +I ++     
Sbjct: 189  KK-FGENFAS-----CQAGISSFYTK-DLIVMGAPGSSYWTGSLF---VYNITTNKYKAF 238

Query: 243  LLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL- 301
            L           D  N   F  Y GYSV  G F    +TTE V GAP     +G   I  
Sbjct: 239  L-----------DKQNQVKFGSYLGYSVGAGHFRSQ-HTTEVVGGAPQHE-QIGKAYIFS 285

Query: 302  --DSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRV 359
              +     LH ++G+++ SYFG SV   D+N DG  DLLVGAP+    R      E GRV
Sbjct: 286  IDEKELNILHEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIR------EEGRV 339

Query: 360  YLFLQPRGPHALGAPSLLLTGTQLY-GRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRG 418
            ++++       + A    L G+  Y  RFG +I  LGD+D DG+ D+A+ AP      +G
Sbjct: 340  FVYINSGSGAVMNAMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDL-QG 398

Query: 419  QVLVFLGQSEGLRSRPSQVLD--SPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQV 476
             + ++ G+++G+ S  SQ ++      + S FG S+ G +D D+NGY D+ VGA+ ++  
Sbjct: 399  AIYIYNGRADGISSTFSQRIEGLQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSA 458

Query: 477  AVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSL- 535
             + R +PVV     L   +S+N     CV  +   P  C ++ +C    G  +P  + L 
Sbjct: 459  VLLRTRPVVIVDASLSHPESVNRTKFDCV--ENGWPSVCIDLTLCFSYKGKEVPGYIVLF 516

Query: 536  -NAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLS 594
             N  L ++R+     R            T ++ +  + +  C T  AF+R   D RD L+
Sbjct: 517  YNMSLDVNRKAESPPRFYFSSNGTSDVITGSIQVSSREAN-CRTHQAFMR--KDVRDILT 573

Query: 595  PIVLSLNVSLPP-------TE--AGMAPAVVLHGDTHVQEQT-RIVLDCGEDDVCVPQLQ 644
            PI +     L P       TE    + P +    +  + ++T      C  ++ C   LQ
Sbjct: 574  PIQIEAAYHLGPHVISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN-CSADLQ 632

Query: 645  LTASV-------TGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNV 697
            ++A +         + L VG+   L L +   N G+ AYE  L V LP G ++++ L   
Sbjct: 633  VSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIKILELE 692

Query: 698  EGFERLICNQKKENETRVVLCELGNPMKKN-AQIGIAMLVSVGNLEEAGESVSFQLQIRS 756
            E  +++ C     +    + C +G     + ++I I+ L+ V +L  A E +S  +    
Sbjct: 693  E--KQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATC 750

Query: 757  KNSQ---NPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAA-EEGEREQNSLDSWGPKVE 812
            +N +   N     V + +P++ E ++ + G   P S V  + +E E E   ++    K+ 
Sbjct: 751  ENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFVNPTSFVYGSNDENEPETCMVE----KMN 806

Query: 813  HTYELHNNGPGTVNGLHLSIHLPGQSQP--SDLLYILDIQPQGGLQCFPQPPVNPLKVDW 870
             T+ + N G      + + I +P    P    L  ILD+Q   G +C             
Sbjct: 807  LTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLFNILDVQTTTG-EC------------- 852

Query: 871  GLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQ------------DPVLVSCDSAP--C 916
                         H +  +R   L   +Q S +Q            D  L+ C  A   C
Sbjct: 853  -------------HFENYQRVCAL--EQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHC 897

Query: 917  TVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAW---FNVSSLPYAVPPL 973
                C+  +M  G+ A V +        L  RP    + ++ A       +  P   P +
Sbjct: 898  LNFLCNFGKMESGKEASVHI-------QLEGRPSILEMDETSALKFEIRATGFPEPNPRV 950

Query: 974  SLPRGEAQVWTQLLRALEERAIPIWWVLV----GVLGGLLLLTILVLAMWKVGFFKRNRP 1029
                 +  V   LL  L  +    ++ +V     +L GL++L ++   MWK GFFKR   
Sbjct: 951  IELNKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYK 1010

Query: 1030 PLEEDD 1035
             + +++
Sbjct: 1011 SILQEE 1016


>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
          Length = 1044

 Score =  246 bits (628), Expect = 8e-65
 Identities = 275/973 (28%), Positives = 434/973 (44%), Gaps = 157/973 (16%)

Query: 158  VGSCFLAQPESGRR-----AEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGEL 212
            +G CF+   +   R      E+  C G    R      F + ++   A FS     +  L
Sbjct: 63   IGRCFVLSQDLAIRDELDGGEWKFCEG----RPQGHEQFGFCQQGTAAAFSP---DSHYL 115

Query: 213  VLGAPGGYYFLG-----LLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWG 267
            + GAPG Y + G     L AQ           P    +    +        P   + Y+G
Sbjct: 116  LFGAPGTYNWKGTARVELCAQGSADLAHLDDGP----YEAGGEKEQDPRLIPVPANSYFG 171

Query: 268  YSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL--DSYYQRLHR--LRGEQMASYFGHS 323
            +S+  G+         +V GAP  +   GAV IL  DS  + +    L GE++ S FG+S
Sbjct: 172  FSIDSGKGLVRAEELSFVAGAPRANHK-GAVVILRKDSASRLVPEVMLSGERLTSGFGYS 230

Query: 324  VAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQL 383
            +AV D+N DG  DL+VGAP + E + +      G VY++L  +G H  G   L L G+  
Sbjct: 231  LAVADLNSDGWPDLIVGAPYFFERQEELG----GAVYVYLN-QGGHWAGISPLRLCGSP- 284

Query: 384  YGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFP 443
               FG ++A LGDL++DG+ DIAV AP+ G    G+V ++ G S G+ ++PSQVL+    
Sbjct: 285  DSMFGISLAVLGDLNQDGFPDIAVGAPFDGD---GKVFIYHGSSLGVVAKPSQVLEGEAV 341

Query: 444  TGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKS 503
               +FG+SL G++D+D N YPDL+VG+  A+   ++RA+P++  S ++ +      A +S
Sbjct: 342  GIKSFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPILHVSHEVSI------APRS 394

Query: 504  CVLPQTKTPVS---CFNIQMCVG--ATGHNIPQKLSLNAELQLDRQKPRQGR--RVLLLG 556
              L Q         C ++++C    A   +    ++L+  L  D  +  +G+  RV  L 
Sbjct: 395  IDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLS 454

Query: 557  -------SQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSL-PPTE 608
                    Q +GT     L  +H  +C   M  L++  + +DKL  IV++L+ SL  P  
Sbjct: 455  RNLEEPKHQASGTVW---LKHQHDRVCGDAMFQLQE--NVKDKLRAIVVTLSYSLQTPRL 509

Query: 609  AGMAP-------AVVLHGDTHVQEQTRIVL---DCGEDDVCVPQLQLTA----------- 647
               AP       A +L+      ++  I      CGED +C   LQL             
Sbjct: 510  RRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTE 569

Query: 648  ---------------SVTGSPLLVGADNVLELQMDAAN---EGEGAYEAELAVHLPQGAH 689
                           +++G P++     V  L  D A    +G+ A+EA+L V LP   H
Sbjct: 570  FQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLH 629

Query: 690  Y--MRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGES 747
            Y  +RAL   +  E+ +C    EN + V  CELGNPMK+ AQ+   +++S   +      
Sbjct: 630  YSGVRAL---DPAEKPLC-LSNENASHVE-CELGNPMKRGAQVTFYLILSTSGISIETTE 684

Query: 748  VSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVEL----RGNSFPASLVVA-AEEGEREQN 802
            +  +L + + + Q       L  V  RA   +EL     G + P  L  +    GER   
Sbjct: 685  LEVELLLATISEQE------LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQ 738

Query: 803  SLDSWGPKVEHTYELHNNGPG--TVNGLHLSIHLPGQ-SQPSDLLYILDIQPQGGLQCFP 859
            S    G KV++   + N G    T+    L+I  P + +    LLY + ++ +GG     
Sbjct: 739  SERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGG----- 793

Query: 860  QPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFL--PEPEQPSRLQDP----------- 906
            Q P        GL  P P+ +H     RDRR+  L  PE ++P   Q+P           
Sbjct: 794  QGPGQK-----GLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAE 848

Query: 907  ----VLVSC--DSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAW 960
                + + C   +A C V  C L    R   A++ V   LW  +  +       L+    
Sbjct: 849  KKKNITLDCARGTANCVVFSCPLYSFDRA--AVLHVWGRLWNSTFLEEYSAVKSLEVIVR 906

Query: 961  FNVSSLPYAVPPLSLPRGEAQVWTQLL---RALEERAIPIWWVLVGVLGGLLLLTILVLA 1017
             N+ ++  ++  L L      +   +     A+    +P W +L+ VL GLL+L +LVL 
Sbjct: 907  ANI-TVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLL 965

Query: 1018 MWKVGFFKRNRPP 1030
            +WK+GFFKR + P
Sbjct: 966  LWKMGFFKRAKHP 978


>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo
            sapiens]
          Length = 1073

 Score =  236 bits (602), Expect = 8e-62
 Identities = 271/1072 (25%), Positives = 469/1072 (43%), Gaps = 150/1072 (13%)

Query: 44   GPNGSQFGFSLDFH--KDSHGRVAIVVGAPRTLG-PSQE--ETGGVFLCPWRAEGGQCPS 98
            G  GS FGFSL  H       +  ++VGAPR    P Q    TGG++ C   A G  C  
Sbjct: 38   GDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGLYSCDITARG-PCTR 96

Query: 99   LLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSD--VIVACAPWQHWNVLEKTEEAEKT 156
            + FD      N    T ++ K  Q +G +V S      +V CA          T++  + 
Sbjct: 97   IEFD------NDADPTSES-KEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRD 149

Query: 157  PVGSCFLAQP-----ESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGE 211
              G C++        +     ++S C G    R+     F      C+ G ++  T+   
Sbjct: 150  IFGRCYVLSQNLRIEDDMDGGDWSFCDG----RLRGHEKFG----SCQQGVAATFTKDFH 201

Query: 212  -LVLGAPGGYYFLGLLAQAPVADIF---SSYRPGILLWHVSSQSLSFDSSNPEYFDGYWG 267
             +V GAPG Y + G++      + F   + +  G   + V  ++   +S  P   + Y G
Sbjct: 202  YIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGP--YEVGGETEHDESLVPVPANSYLG 259

Query: 268  YSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLR-----GEQMASYFGH 322
            +S+  G+     +   +V GAP  + + GAV +L    +  H L      GE +AS FG+
Sbjct: 260  FSLDSGKGIVSKDEITFVSGAPRANHS-GAVVLLKRDMKSAHLLPEHIFDGEGLASSFGY 318

Query: 323  SVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQ 382
             VAV D+N DG  D+++GAP Y     DR     G VY+++  +G      P + L GT+
Sbjct: 319  DVAVVDLNKDGWQDIVIGAPQYF----DRDGEVGGAVYVYMNQQGRWNNVKP-IRLNGTK 373

Query: 383  LYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPF 442
                FG A+  +GD+++DGY DIAV APY      G+V ++ G + G+ ++P+QVL    
Sbjct: 374  -DSMFGIAVKNIGDINQDGYPDIAVGAPY---DDLGKVFIYHGSANGINTKPTQVLKGIS 429

Query: 443  PTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVK 502
            P    FG+S+ G +D+D N YPD+ VG+  ++ V ++R++PV+     + V  +     +
Sbjct: 430  PY---FGYSIAGNMDLDRNSYPDVAVGSL-SDSVTIFRSRPVINIQKTITVTPNRIDLRQ 485

Query: 503  --SCVLPQTKTPVSCFNIQMCVGAT----GHNIPQKLSLNAELQLDRQKPRQGRRVLLLG 556
              +C  P       C  ++ C   T    G+N    +    E + +R+K     RV    
Sbjct: 486  KTACGAPSG----ICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRN 541

Query: 557  S-QQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEA----GM 611
               +   T  L L  +   +C     +L+D  + RDKL PI ++ +V +    +      
Sbjct: 542  QGSEPKYTQELTLKRQKQKVCMEETLWLQD--NIRDKLRPIPITASVEIQEPSSRRRVNS 599

Query: 612  APAVV----------LHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVT----------- 650
             P V+           H D H  ++      CG+D+VC   L+L                
Sbjct: 600  LPEVLPILNSDEPKTAHIDVHFLKE-----GCGDDNVCNSNLKLEYKFCTREGNQDKFSY 654

Query: 651  -----GSPLLVGADNV-LELQMDAAN----------EGEGAYEAELAVHLPQGAHYMRAL 694
                 G P LV  D   + L++   N          +G+ A+EA+L    P    Y  A 
Sbjct: 655  LPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYS-AY 713

Query: 695  SNVEGF-ERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQ 753
              +  F E+ +     +N ++   CELGNP K+N+ +   +++S   +      +   L+
Sbjct: 714  RELRAFPEKQLSCVANQNGSQAD-CELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLK 772

Query: 754  IRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEE-GEREQNSLDSWGPKVE 812
            + + ++Q+ N   +     V  E  + + G + P+ +       GE+   S D  G  +E
Sbjct: 773  LETTSNQD-NLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIE 831

Query: 813  HTYELHNNGPGTVN--GLHLSIHLPGQ-SQPSDLLYILDIQPQG--GLQCFPQPPVNPLK 867
            + + + N G    N     L+I  P + S    LLY++ ++ +G   + C PQ  +N L 
Sbjct: 832  YEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLN 891

Query: 868  VDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRL-----QDPVLVSCD-SAPCTVVQC 921
            +              +H+ R +R+I   + +   +      +    ++C  +  C  ++C
Sbjct: 892  LT------------ESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRC 939

Query: 922  DLQEMARGQRAMVTVLAFLWLPSLYQR--PLDQFVLQSHAWFNVSSLPYAVPPLSLPRGE 979
             L+ +    +A + + + LW  +  +    L+   +   A+ +V++   A   + LP   
Sbjct: 940  PLRGL--DSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTA---AAENIRLPNAG 994

Query: 980  AQVWTQLLRA---LEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNR 1028
             QV   +  +    +   +P W +LV +L G+L+L +LV  +WK GFFKRN+
Sbjct: 995  TQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNK 1046


>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo
            sapiens]
          Length = 1091

 Score =  235 bits (600), Expect = 1e-61
 Identities = 271/1072 (25%), Positives = 469/1072 (43%), Gaps = 150/1072 (13%)

Query: 44   GPNGSQFGFSLDFH--KDSHGRVAIVVGAPRTLG-PSQE--ETGGVFLCPWRAEGGQCPS 98
            G  GS FGFSL  H       +  ++VGAPR    P Q    TGG++ C   A G  C  
Sbjct: 38   GDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGLYSCDITARG-PCTR 96

Query: 99   LLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSD--VIVACAPWQHWNVLEKTEEAEKT 156
            + FD      N    T ++ K  Q +G +V S      +V CA          T++  + 
Sbjct: 97   IEFD------NDADPTSES-KEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRD 149

Query: 157  PVGSCFLAQP-----ESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGE 211
              G C++        +     ++S C G    R+     F      C+ G ++  T+   
Sbjct: 150  IFGRCYVLSQNLRIEDDMDGGDWSFCDG----RLRGHEKFG----SCQQGVAATFTKDFH 201

Query: 212  -LVLGAPGGYYFLGLLAQAPVADIF---SSYRPGILLWHVSSQSLSFDSSNPEYFDGYWG 267
             +V GAPG Y + G++      + F   + +  G   + V  ++   +S  P   + Y G
Sbjct: 202  YIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGP--YEVGGETEHDESLVPVPANSYLG 259

Query: 268  YSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLR-----GEQMASYFGH 322
            +S+  G+     +   +V GAP  + + GAV +L    +  H L      GE +AS FG+
Sbjct: 260  FSLDSGKGIVSKDEITFVSGAPRANHS-GAVVLLKRDMKSAHLLPEHIFDGEGLASSFGY 318

Query: 323  SVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQ 382
             VAV D+N DG  D+++GAP Y     DR     G VY+++  +G      P + L GT+
Sbjct: 319  DVAVVDLNKDGWQDIVIGAPQYF----DRDGEVGGAVYVYMNQQGRWNNVKP-IRLNGTK 373

Query: 383  LYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPF 442
                FG A+  +GD+++DGY DIAV APY      G+V ++ G + G+ ++P+QVL    
Sbjct: 374  -DSMFGIAVKNIGDINQDGYPDIAVGAPY---DDLGKVFIYHGSANGINTKPTQVLKGIS 429

Query: 443  PTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVK 502
            P    FG+S+ G +D+D N YPD+ VG+  ++ V ++R++PV+     + V  +     +
Sbjct: 430  PY---FGYSIAGNMDLDRNSYPDVAVGSL-SDSVTIFRSRPVINIQKTITVTPNRIDLRQ 485

Query: 503  --SCVLPQTKTPVSCFNIQMCVGAT----GHNIPQKLSLNAELQLDRQKPRQGRRVLLLG 556
              +C  P       C  ++ C   T    G+N    +    E + +R+K     RV    
Sbjct: 486  KTACGAPSG----ICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRN 541

Query: 557  S-QQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEA----GM 611
               +   T  L L  +   +C     +L+D  + RDKL PI ++ +V +    +      
Sbjct: 542  QGSEPKYTQELTLKRQKQKVCMEETLWLQD--NIRDKLRPIPITASVEIQEPSSRRRVNS 599

Query: 612  APAVV----------LHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVT----------- 650
             P V+           H D H  ++      CG+D+VC   L+L                
Sbjct: 600  LPEVLPILNSDEPKTAHIDVHFLKE-----GCGDDNVCNSNLKLEYKFCTREGNQDKFSY 654

Query: 651  -----GSPLLVGADNV-LELQMDAAN----------EGEGAYEAELAVHLPQGAHYMRAL 694
                 G P LV  D   + L++   N          +G+ A+EA+L    P    Y  A 
Sbjct: 655  LPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYS-AY 713

Query: 695  SNVEGF-ERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQ 753
              +  F E+ +     +N ++   CELGNP K+N+ +   +++S   +      +   L+
Sbjct: 714  RELRAFPEKQLSCVANQNGSQAD-CELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLK 772

Query: 754  IRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEE-GEREQNSLDSWGPKVE 812
            + + ++Q+ N   +     V  E  + + G + P+ +       GE+   S D  G  +E
Sbjct: 773  LETTSNQD-NLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIE 831

Query: 813  HTYELHNNGPGTVN--GLHLSIHLPGQ-SQPSDLLYILDIQPQG--GLQCFPQPPVNPLK 867
            + + + N G    N     L+I  P + S    LLY++ ++ +G   + C PQ  +N L 
Sbjct: 832  YEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLN 891

Query: 868  VDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRL-----QDPVLVSCD-SAPCTVVQC 921
            +              +H+ R +R+I   + +   +      +    ++C  +  C  ++C
Sbjct: 892  LT------------ESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRC 939

Query: 922  DLQEMARGQRAMVTVLAFLWLPSLYQR--PLDQFVLQSHAWFNVSSLPYAVPPLSLPRGE 979
             L+ +    +A + + + LW  +  +    L+   +   A+ +V++   A   + LP   
Sbjct: 940  PLRGL--DSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTA---AAENIRLPNAG 994

Query: 980  AQVWTQLLRA---LEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNR 1028
             QV   +  +    +   +P W +LV +L G+L+L +LV  +WK GFFKR+R
Sbjct: 995  TQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRSR 1046


>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
          Length = 1179

 Score =  187 bits (476), Expect = 3e-47
 Identities = 210/880 (23%), Positives = 362/880 (41%), Gaps = 106/880 (12%)

Query: 192  SWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQS 251
            S++    + GFS+  +Q   ++LGA G Y + G +     + I     P    ++V S  
Sbjct: 372  SFEMEMSQTGFSAHYSQDW-VMLGAVGAYDWNGTVVMQKASQIII---PRNTTFNVES-- 425

Query: 252  LSFDSSNPEYFDGYWGYSV-AVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL---DSYYQR 307
                +   E    Y GY+V +     GD+    Y+ G P ++ T G V I    D   + 
Sbjct: 426  ----TKKNEPLASYLGYTVNSATASSGDVL---YIAGQPRYNHT-GQVIIYRMEDGNIKI 477

Query: 308  LHRLRGEQMASYFGHSVAVTDVNGDGRHD-LLVGAPLYMESRADRKLAEVGRVYLFL--Q 364
            L  L GEQ+ SYFG  +  TD++ D   D LLVGAP+YM +  +    E G+VY++   Q
Sbjct: 478  LQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKE----EQGKVYVYALNQ 533

Query: 365  PRGPHALGAPSLLLT---------------GTQLYGRFGSAIAPLGDLDRDGYNDIAVAA 409
             R  + +    +  T                     RFG+AIA + DL+ DG+NDI + A
Sbjct: 534  TRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGA 593

Query: 410  PYGGPSGRGQVLVFLGQSEGLRSRPSQVLDS--PFPTGSAFGFSLRGAVDIDDNGYPDLI 467
            P     G G V ++ G  + +R   +Q + S     T   FG S+ G +D++ +G  D+ 
Sbjct: 594  PLEDDHG-GAVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVT 652

Query: 468  VGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGA--- 524
            +G  G   +   R   VVK ++     + +N   K+C +   +T   C N  +C      
Sbjct: 653  IGGLGGAALFWSRDVAVVKVTMNF-EPNKVNIQKKNCHMEGKETV--CINATVCFDVKLK 709

Query: 525  TGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLR 584
            +  +   +  L   + LD    RQ  R    G+Q+     N+ +       C     ++ 
Sbjct: 710  SKEDTIYEADLQYRVTLDSL--RQISRSFFSGTQERKVQRNITVRKSE---CTKHSFYML 764

Query: 585  DEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQ 644
            D+ DF+D +    ++L+ +L   E G      L    H  E      DCG  + C+  L 
Sbjct: 765  DKHDFQDSVR---ITLDFNLTDPENGPVLDDSLPNSVH--EYIPFAKDCGNKEKCISDLS 819

Query: 645  LTASVTGSPLLV--GADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFER 702
            L  + T   LL+    ++   + +   N  + AY     VH      +    S +E  ++
Sbjct: 820  LHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVF----SGIEAIQK 875

Query: 703  LICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNP 762
              C          + C++G P  +  ++    ++   N     E+V+  L   S + + P
Sbjct: 876  DSCESNHN-----ITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPP 930

Query: 763  NS---KIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQ-NSLDSWGPKVEHTYELH 818
             +    +V + +PV+ E  ++   ++    + +AA E   E  NS +  G ++   Y + 
Sbjct: 931  ETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIR 990

Query: 819  NNGPGTVNGLHLSIHLPGQ-SQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSP 877
             +G   +  L LSI  P   S    +LY   +       C P    +P  ++ G  + + 
Sbjct: 991  KSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTS 1050

Query: 878  SPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVL 937
            +     H KR                    ++ C++     + C+L      Q   V V 
Sbjct: 1051 TD----HLKRG------------------TILDCNTCKFATITCNLTSSDISQ---VNVS 1085

Query: 938  AFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPI 997
              LW P+  +       L         +       LS    + ++  Q+ +      +P+
Sbjct: 1086 LILWKPTFIKSYFSSLNLTIRGELRSENASLV---LSSSNQKRELAIQISKDGLPGRVPL 1142

Query: 998  WWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEE 1037
            W +L+    GLLLL +L+LA+WK+GFFKR   PL++  E+
Sbjct: 1143 WVILLSAFAGLLLLMLLILALWKIGFFKR---PLKKKMEK 1179



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 24/96 (25%), Positives = 46/96 (47%), Gaps = 7/96 (7%)

Query: 16  WVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLG 75
           W+L ++  C      + N+D      ++GP    FG+++  +++  G+  +++G+P  +G
Sbjct: 17  WLLTVVLRCCV----SFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGK-WVLIGSP-LVG 70

Query: 76  PSQEETGGVFLCP-WRAEGGQCPSLLFDLRDETRNV 110
             +  TG V+ CP  R E   C  L   +     NV
Sbjct: 71  QPKNRTGDVYKCPVGRGESLPCVKLDLPVNTSIPNV 106


>gi|62548866 integrin, alpha D precursor [Homo sapiens]
          Length = 1161

 Score =  170 bits (431), Expect = 6e-42
 Identities = 221/880 (25%), Positives = 366/880 (41%), Gaps = 117/880 (13%)

Query: 192  SWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLW--HVSS 249
            S+     + GFS+ +T  G L LGA G + + G                G  L+  ++S 
Sbjct: 345  SFQHEMSQEGFSTALTMDG-LFLGAVGSFSWSG----------------GAFLYPPNMSP 387

Query: 250  QSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEI--LDSYYQR 307
              ++    N +  D Y GYS  +  + G  N    V+GAP +  T  AV    +   +++
Sbjct: 388  TFINMSQENVDMRDSYLGYSTELALWKGVQNL---VLGAPRYQHTGKAVIFTQVSRQWRK 444

Query: 308  LHRLRGEQMASYFGHSVAVTDVNGDGRHDL-LVGAPLYMESRADRKLAEVGRVYLFLQPR 366
               + G Q+ SYFG S+   DV+ DG  DL L+GAP Y E          G+V +   PR
Sbjct: 445  KAEVTGTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYEQTRG------GQVSVCPLPR 498

Query: 367  GPHALGAPSLLLTGTQ--LYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFL 424
            G         +L G Q   +GRFG+A+  LGD++ D   D+A+ AP G    RG V +F 
Sbjct: 499  G-RVQWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAP-GEQENRGAVYLFH 556

Query: 425  GQSE-GLRSRPSQVLDSP--FPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRA 481
            G SE G+    SQ + S    P    FG +L G  D+  +G  DL VGA G  QV + R+
Sbjct: 557  GASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVGARG--QVLLLRS 614

Query: 482  QPVVKASVQLLVQD-SLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQ 540
             PV+K  V +      +  AV  C   +  + +   +  +C+     ++ Q   + + ++
Sbjct: 615  LPVLKVGVAMRFSPVEVAKAVYRC-WEEKPSALEAGDATVCLTIQKSSLDQLGDIQSSVR 673

Query: 541  LD--RQKPRQGRRVLLLGSQQAGTTLNLDLG-GKHSPICHTTMAFLRDEADFRDKLSPIV 597
             D      R   R +   ++    T    LG G H   C T    L D  +  D +SPI+
Sbjct: 674  FDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIH---CETLKLLLPDCVE--DVVSPII 728

Query: 598  LSLNVSLP----PTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTG-S 652
            L LN SL     P+   + P + +              +CG+D +C   L +T S +G  
Sbjct: 729  LHLNFSLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTLSFSGLQ 788

Query: 653  PLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNV----EGFERLICN-- 706
             L VG+   L + +   N GE +Y   ++++ P G  + R         +   RL C   
Sbjct: 789  TLTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETV 848

Query: 707  QKKENETRVVLCELGNPMKKNAQIGIAMLV-SVGNLEEAGESVSFQLQIRSKNSQNPNSK 765
              ++   R   C + +P+      G  ++   V      G+ +  +    S+N++  +SK
Sbjct: 849  PTEDEGLRSSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASSENNKASSSK 908

Query: 766  IVL-LDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGT 824
                L++PV+      +            A   E++         + EH Y ++N    +
Sbjct: 909  ATFQLELPVKYAVYTMISRQEESTKYFNFATSDEKKMK-------EAEHRYRVNNL---S 958

Query: 825  VNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAH 884
               L +SI+                        F  P +      W + + +PS   P  
Sbjct: 959  QRDLAISIN------------------------FWVPVLLNGVAVWDVVMEAPSQSLPCV 994

Query: 885  HKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTV---LAFLW 941
             +R   Q      +  +++    ++ C  A C   +CD+   +  +    T+   L+F W
Sbjct: 995  SERKPPQ----HSDFLTQISRSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGW 1050

Query: 942  LPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEE----RAIPI 997
            +    Q+   + ++ S A     +  Y+     LP  EA +  Q+   LEE     AIPI
Sbjct: 1051 VRETLQK---KVLVVSVAEITFDTSVYS----QLPGQEAFMRAQMEMVLEEDEVYNAIPI 1103

Query: 998  WWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEE 1037
              ++   +G LLLL ++   ++K+GFFKR+   + ED  E
Sbjct: 1104 --IMGSSVGALLLLALITATLYKLGFFKRHYKEMLEDKPE 1141


>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
          Length = 1181

 Score =  169 bits (427), Expect = 2e-41
 Identities = 213/881 (24%), Positives = 370/881 (41%), Gaps = 106/881 (12%)

Query: 187  VENDFSWDKRYCEAGFSSVVTQAGE-LVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLW 245
            V+   ++     + GFS+  +   + L+LGA G + + G + Q            G L++
Sbjct: 368  VQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKT--------SHGHLIF 419

Query: 246  HVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYY 305
               +        N   + GY   +++ GE      +T +V GAP  ++T G + +L S  
Sbjct: 420  PKQAFDQILQDRNHSSYLGYSVAAISTGE------STHFVAGAPRANYT-GQI-VLYSVN 471

Query: 306  QR-----LHRLRGEQMASYFGHSVAVTDVNGDGRHD-LLVGAPLYMESRADRKLAEVGRV 359
            +      +   RG+Q+ SYFG  +   DV+ D   D LLVGAP+YM   +D K  E GRV
Sbjct: 472  ENGNITVIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYM---SDLKKEE-GRV 527

Query: 360  YLFLQPRGPHALGAPSLLLTGTQLYG-RFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRG 418
            YLF    G   LG    L     +   RFGSAIA L D++ DG+ND+ V +P    +  G
Sbjct: 528  YLFTIKEG--ILGQHQFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNS-G 584

Query: 419  QVLVFLGQSEGLRSRPSQVL---DSPFPTG-SAFGFSLRGAVDIDDNGYPDLIVGAYGAN 474
             V ++ G    +R++ SQ +   D  F +    FG SL G  D++ +   D+ +GA+G  
Sbjct: 585  AVYIYNGHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFG-- 642

Query: 475  QVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSC---FNIQMCVGA----TGH 527
            QV            VQL  Q   + A+++   P+  T V+      +++C  A    T  
Sbjct: 643  QV------------VQLWSQSIADVAIEASFTPEKITLVNKNAQIILKLCFSAKFRPTKQ 690

Query: 528  NIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEA 587
            N    +  N  L  D    R   R L   + +     N+ +    S  C   + ++++ +
Sbjct: 691  NNQVAIVYNITLDADGFSSRVTSRGLFKENNERCLQKNMVVNQAQS--CPEHIIYIQEPS 748

Query: 588  DFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTA 647
            D  + L      L V +     G +PA+  + +T          DCGED +C+  L L  
Sbjct: 749  DVVNSLD-----LRVDISLENPGTSPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDV 803

Query: 648  ----SVTGSPLLVGADNV-LELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFER 702
                +    P +V   N  L   +   N+ E AY   + V   +   +      V+G E 
Sbjct: 804  RQIPAAQEQPFIVSNQNKRLTFSVTLKNKRESAYNTGIVVDFSENLFFASFSLPVDGTE- 862

Query: 703  LICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQ-N 761
            + C      ++  V C++G P  K  Q     +    NL+      S   Q  S++ + N
Sbjct: 863  VTCQVAASQKS--VACDVGYPALKREQQVTFTINFDFNLQNLQNQASLSFQALSESQEEN 920

Query: 762  PNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQ--NSLDSWGPKVEHTYELHN 819
                +V L +P+  +A++ L   S   +    + +G      +S +  GPK   + ++  
Sbjct: 921  KADNLVNLKIPLLYDAEIHLT-RSTNINFYEISSDGNVPSIVHSFEDVGPKFIFSLKV-T 978

Query: 820  NGPGTVNGLHLSIHLPGQSQPSD-LLYILDIQPQ--GGLQCFPQPPVNPLKVDWGLPIPS 876
             G   V+   + IH+P  ++  + L+Y+  +Q    G + C     +NPLK+       S
Sbjct: 979  TGSVPVSMATVIIHIPQYTKEKNPLMYLTGVQTDKAGDISC--NADINPLKIGQ----TS 1032

Query: 877  PSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTV 936
             S    + + R  +++                 +C +A C+ V C L+++       V V
Sbjct: 1033 SSVSFKSENFRHTKEL-----------------NCRTASCSNVTCWLKDVHMKGEYFVNV 1075

Query: 937  LAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIP 996
               +W  +          L + A  N  +    V    +      +   +++  E+  +P
Sbjct: 1076 TTRIWNGTFASSTFQTVQLTAAAEINTYNPEIYV----IEDNTVTIPLMIMKPDEKAEVP 1131

Query: 997  IWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEE 1037
               ++  ++ G+LLL  LV  +WK+GFFKR    + ++ +E
Sbjct: 1132 TGVIIGSIIAGILLLLALVAILWKLGFFKRKYEKMTKNPDE 1172


>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
          Length = 1167

 Score =  156 bits (395), Expect = 8e-38
 Identities = 201/769 (26%), Positives = 320/769 (41%), Gaps = 101/769 (13%)

Query: 296  GAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHD-LLVGAPLYMESRADRKLA 354
            GAV +  S       L+GEQ+ SYFG  +   D + DG  D LLV AP+++  +      
Sbjct: 469  GAVRVAQS-------LQGEQIGSYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQNK---- 517

Query: 355  EVGRVYLFLQPRGPHALGAPSLL-LTGT-----QLYGRFGSAIAPLGDLDRDGYNDIAVA 408
            E GRVY++L       +G  SLL L GT         RFG A+  L DL++DG+ D+AV 
Sbjct: 518  ETGRVYVYL-------VGQQSLLTLQGTLQPEPPQDARFGFAMGALPDLNQDGFADVAVG 570

Query: 409  APYGGPSGRGQVLVFLGQSEGLRSRPSQ-VLDSPFPTG-SAFGFSLRGAVDIDDNGYPDL 466
            AP      +G + ++ G   G+R  P+Q +  +  P   S FG S+ G +D+D +   D+
Sbjct: 571  APL-EDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSYFGRSVDGRLDLDGDDLVDV 629

Query: 467  IVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATG 526
             VGA GA    +  ++P+V  +  L V       V+     + +  V C    +C   T 
Sbjct: 630  AVGAQGA--AILLSSRPIVHLTPSLEVTPQAISVVQRDCRRRGQEAV-CLTAALCFQVTS 686

Query: 527  H---NIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQ--AGTTLNLDLGGKHSPICHTTMA 581
                    +  +     LD      G R    GS Q  +   L L +G   +  C     
Sbjct: 687  RTPGRWDHQFYMRFTASLDEW--TAGARAAFDGSGQRLSPRRLRLSVG---NVTCEQLHF 741

Query: 582  FLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLH--GDTHVQEQTRIVLDCGEDDVC 639
             + D +D+   L P+ L++  +L  T     P  VL+    T +Q+      DCG D+ C
Sbjct: 742  HVLDTSDY---LRPVALTVTFALDNT---TKPGPVLNEGSPTSIQKLVPFSKDCGPDNEC 795

Query: 640  VPQ--LQLTASVTGS---PLLV-GADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRA 693
            V    LQ+   + GS   P +V G    + +     N  E AY   L++   +  H    
Sbjct: 796  VTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLENRKENAYNTSLSLIFSRNLHLASL 855

Query: 694  LSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQ 753
                E   ++ C     +     LC +G+P+ +      A +  +   E +  S+  Q+ 
Sbjct: 856  TPQRESPIKVECAAPSAHAR---LCSVGHPVFQTG----AKVTFLLEFEFSCSSLLSQVF 908

Query: 754  IR-SKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLD-SWGPKV 811
            ++ + +S +      L D   +  A ++   +   +S             +L    GP+ 
Sbjct: 909  VKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSESTLHRYEVHPYGTLPVGPGPEF 968

Query: 812  EHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWG 871
            + T  + N G   V+GL +S  LP  +   +    L         C  Q    P      
Sbjct: 969  KTTLRVQNLGCYVVSGLIISALLPAVAHGGNYFLSLSQVITNNASCIVQNLTEP------ 1022

Query: 872  LPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQR 931
               P P P+H                  P  LQ    ++  +  C VV+C L ++A+G  
Sbjct: 1023 ---PGP-PVH------------------PEELQHTNRLNGSNTQCQVVRCHLGQLAKGTE 1060

Query: 932  AMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQ-LLRAL 990
              V +L  +      +       + S   F + +   +V  L+    EA  W++ LL  +
Sbjct: 1061 VSVGLLRLVHNEFFRRAKFKSLTVVS--TFELGTEEGSVLQLT----EASRWSESLLEVV 1114

Query: 991  EERAIPI-WWVLVG-VLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEE 1037
            + R I I  W+L+G VLGGLLLL +LV  +WK+GFF   + P EE  EE
Sbjct: 1115 QTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIPEEEKREE 1163



 Score = 35.0 bits (79), Expect = 0.37
 Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 7/72 (9%)

Query: 17 VLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGP 76
          ++ L G C+       NLD      + GP  ++FG+S+  H    G+  ++VGAP   GP
Sbjct: 13 LVFLTGLCSP-----FNLDEHHPRLFPGPPEAEFGYSVLQHVGG-GQRWMLVGAPWD-GP 65

Query: 77 SQEETGGVFLCP 88
          S +  G V+ CP
Sbjct: 66 SGDRRGDVYRCP 77


>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
          Length = 1153

 Score =  149 bits (377), Expect = 1e-35
 Identities = 214/891 (24%), Positives = 352/891 (39%), Gaps = 155/891 (17%)

Query: 192  SWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQS 251
            S++    + GFS+ +T  G L L   G Y + G                G+ L+    +S
Sbjct: 345  SFEHEMSQEGFSAAITSNGPL-LSTVGSYDWAG----------------GVFLYTSKEKS 387

Query: 252  --LSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL---DSYYQ 306
              ++    + +  D Y GY+ A+   +        V+GAP +   +G V +       ++
Sbjct: 388  TFINMTRVDSDMNDAYLGYAAAIILRN---RVQSLVLGAPRYQH-IGLVAMFRQNTGMWE 443

Query: 307  RLHRLRGEQMASYFGHSVAVTDVNGDGRHDL-LVGAPLYMESRADRKLAEVGRVYLFLQP 365
                ++G Q+ +YFG S+   DV+ +G  DL L+GAP Y E          G+V +   P
Sbjct: 444  SNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRG------GQVSVCPLP 497

Query: 366  RGPHALGAPSLLLTGTQ--LYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVF 423
            RG  A      +L G Q   +GRFG+A+  LGD++ D   D+A+ AP G    RG V +F
Sbjct: 498  RGQRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLF 556

Query: 424  LGQS-EGLRSRPSQVLDSP--FPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYR 480
             G S  G+    SQ +      P    FG SL G  D+  +G  DL VGA G   V + R
Sbjct: 557  HGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLR 614

Query: 481  AQPVVKAS---------VQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQ 531
            +QPV++           V   V +  +  VK     + +    C ++Q            
Sbjct: 615  SQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRV---CLHVQKSTRDRLREGQI 671

Query: 532  KLSLNAELQLDRQKPRQG-----------RRVLLLGSQQAGTTLNLDLGGKHSPICHTTM 580
            +  +  +L LD  +P              R+  +LG  Q   TL L L     P C    
Sbjct: 672  QSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQL-----PNC---- 722

Query: 581  AFLRDEADFRDKLSPIVLSLNVSLPPTE----AGMAPAVVLHGDTHVQEQTRIVLDCGED 636
                      D +SPIVL LN SL  T       + P +                +CG D
Sbjct: 723  --------IEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGND 774

Query: 637  DVCVPQLQLTASVTGSP-LLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALS 695
            ++C   L +T S      L+VG      + +   N+GE +Y  ++    P    Y R +S
Sbjct: 775  NICQDDLSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSY-RKVS 833

Query: 696  NVEGFE-----RLICNQKKENETRVVL----CELGNPM-KKNAQIGIAMLVSVGNLEEAG 745
             ++        RL C      E    L    C + +P+  +N+++   +   V +    G
Sbjct: 834  TLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLG 893

Query: 746  ESVSFQLQIRSKNSQNPNSKIVL-LDVPVRAEAQVELRGNSFPASLV--VAAEEGEREQN 802
              +  +  + S+N+    +K    L++PV+    + +  +      +   A+E   R   
Sbjct: 894  NKLLLKANVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSR--- 950

Query: 803  SLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPP 862
                    ++H Y++ N G               +S P  L++++ ++            
Sbjct: 951  -------VMQHQYQVSNLGQ--------------RSLPISLVFLVPVRLN---------- 979

Query: 863  VNPLKVDWGLP-IPSPSPIHPAHHKRDRRQIFLP-EPEQPSRLQDPVLVSCDSAPCTVVQ 920
                 V W  P +     +    H ++R    LP   +  + L+   +V+C  A C  +Q
Sbjct: 980  ---QTVIWDRPQVTFSENLSSTCHTKER----LPSHSDFLAELRKAPVVNCSIAVCQRIQ 1032

Query: 921  CDLQEMARGQRAMVTV---LAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPR 977
            CD+      +    T+   L+F W        L   V  +   FN S          LP 
Sbjct: 1033 CDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHL-LIVSTAEILFNDSVFTL------LPG 1085

Query: 978  GEAQVWTQLLRALE--ERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKR 1026
              A V +Q    +E  E   P+  ++   +GGLLLL ++  A++K+GFFKR
Sbjct: 1086 QGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKR 1136


>gi|34452173 integrin alpha X precursor [Homo sapiens]
          Length = 1163

 Score =  145 bits (367), Expect = 1e-34
 Identities = 218/889 (24%), Positives = 353/889 (39%), Gaps = 137/889 (15%)

Query: 192  SWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLW--HVSS 249
            S++    + GFS+V T  G  VLGA G + + G                G  L+  ++S 
Sbjct: 346  SFELEMAQEGFSAVFTPDGP-VLGAVGSFTWSG----------------GAFLYPPNMSP 388

Query: 250  QSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEI--LDSYYQR 307
              ++    N +  D Y GYS  +  + G       V+GAP +  T  AV    +   ++ 
Sbjct: 389  TFINMSQENVDMRDSYLGYSTELALWKG---VQSLVLGAPRYQHTGKAVIFTQVSRQWRM 445

Query: 308  LHRLRGEQMASYFGHSVAVTDVNGDGRHDL-LVGAPLYMESRADRKLAEVGRVYLFLQPR 366
               + G Q+ SYFG S+   DV+ DG  DL L+GAP Y E          G+V +   PR
Sbjct: 446  KAEVTGTQIGSYFGASLCSVDVDSDGSTDLVLIGAPHYYEQTRG------GQVSVCPLPR 499

Query: 367  GPHALGAPSLLLTGTQ--LYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVF- 423
            G       ++L  G Q   +GRFG+A+  LGD++ D   D+ + AP G    RG V +F 
Sbjct: 500  GWRRWWCDAVLY-GEQGHPWGRFGAALTVLGDVNGDKLTDVVIGAP-GEEENRGAVYLFH 557

Query: 424  --LGQSEGLRSRPSQVLDSPFPTG-SAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYR 480
              LG S    S   ++  S   +    FG +L G  D+  +G  DL VGA G  QV + R
Sbjct: 558  GVLGPSIS-PSHSQRIAGSQLSSRLQYFGQALSGGQDLTQDGLVDLAVGARG--QVLLLR 614

Query: 481  AQPV--VKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAE 538
             +PV  V  S+Q +  +    A +      ++  +   NI + +     N+     L + 
Sbjct: 615  TRPVLWVGVSMQFIPAEIPRSAFECREQVVSEQTLVQSNICLYIDKRSKNLLGSRDLQSS 674

Query: 539  LQLD---------------RQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFL 583
            + LD                 K R   RV +LG +      NL L     P C       
Sbjct: 675  VTLDLALDPGRLSPRATFQETKNRSLSRVRVLGLKAHCENFNLLL-----PSC------- 722

Query: 584  RDEADFRDKLSPIVLSLNVSL--PPTEA--GMAPAVVLHGDTHVQEQTRIVLDCGEDDVC 639
                   D ++PI L LN +L   P  A   + P +      +         +CG D +C
Sbjct: 723  -----VEDSVTPITLRLNFTLVGKPLLAFRNLRPMLAADAQRYFTASLPFEKNCGADHIC 777

Query: 640  VPQLQLTASVTG-SPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVE 698
               L ++ S  G   LLVG++  L  ++   N+GE +Y   +    P G  Y       +
Sbjct: 778  QDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGLSYRYVAEGQK 837

Query: 699  GFE----RLICNQKK--ENETRVVLCELGNPM-KKNAQIGIAMLVSVGNLEEAGESVSFQ 751
              +     L C+        T    C + + + +  AQI       V      G+ +   
Sbjct: 838  QGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAVLGDRLLLT 897

Query: 752  LQIRSKNSQNPNSKIVL-LDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPK 810
              + S+N+    SK    L++PV+      +  +      +  +E  E+E +        
Sbjct: 898  ANVSSENNTPRTSKTTFQLELPVKYAVYTVVSSHEQFTKYLNFSESEEKESH-------V 950

Query: 811  VEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDW 870
              H Y+++N G      L +SI+     + +     +D++           P NP     
Sbjct: 951  AMHRYQVNNLGQ---RDLPVSINFWVPVELNQEAVWMDVE--------VSHPQNPSLRCS 999

Query: 871  GLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQ 930
               I  P+    AH ++                 +PVL  C  A C   +CD+   +  +
Sbjct: 1000 SEKIAPPASDFLAHIQK-----------------NPVL-DCSIAGCLRFRCDVPSFSVQE 1041

Query: 931  RAMVTV---LAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLL 987
                T+   L+F W+  + Q+ +    + S A     +  Y+     LP  EA +  Q  
Sbjct: 1042 ELDFTLKGNLSFGWVRQILQKKVS---VVSVAEITFDTSVYS----QLPGQEAFMRAQTT 1094

Query: 988  RALEERAI--PIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEED 1034
              LE+  +  P   ++   +GGLLLL ++   ++KVGFFKR    + E+
Sbjct: 1095 TVLEKYKVHNPTPLIVGSSIGGLLLLALITAVLYKVGFFKRQYKEMMEE 1143


>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
          Length = 1152

 Score =  145 bits (366), Expect = 2e-34
 Identities = 212/890 (23%), Positives = 351/890 (39%), Gaps = 154/890 (17%)

Query: 192  SWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQS 251
            S++    + GFS+ +T  G L L   G Y + G                G+ L+    +S
Sbjct: 345  SFEHEMSQEGFSAAITSNGPL-LSTVGSYDWAG----------------GVFLYTSKEKS 387

Query: 252  --LSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL---DSYYQ 306
              ++    + +  D Y GY+ A+   +        V+GAP +   +G V +       ++
Sbjct: 388  TFINMTRVDSDMNDAYLGYAAAIILRN---RVQSLVLGAPRYQH-IGLVAMFRQNTGMWE 443

Query: 307  RLHRLRGEQMASYFGHSVAVTDVNGDGRHDL-LVGAPLYMESRADRKLAEVGRVYLFLQP 365
                ++G Q+ +YFG S+   DV+ +G  DL L+GAP Y E          G+V +   P
Sbjct: 444  SNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRG------GQVSVCPLP 497

Query: 366  RGPHALGAPSLLLTGT-QLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFL 424
            RG       ++L     Q +GRFG+A+  LGD++ D   D+A+ AP G    RG V +F 
Sbjct: 498  RGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFH 556

Query: 425  GQS-EGLRSRPSQVLDSP--FPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRA 481
            G S  G+    SQ +      P    FG SL G  D+  +G  DL VGA G   V + R+
Sbjct: 557  GTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRS 614

Query: 482  QPVVKAS---------VQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQK 532
            QPV++           V   V +  +  VK     + +    C ++Q            +
Sbjct: 615  QPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRV---CLHVQKSTRDRLREGQIQ 671

Query: 533  LSLNAELQLDRQKPRQG-----------RRVLLLGSQQAGTTLNLDLGGKHSPICHTTMA 581
              +  +L LD  +P              R+  +LG  Q   TL L L     P C     
Sbjct: 672  SVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQL-----PNC----- 721

Query: 582  FLRDEADFRDKLSPIVLSLNVSLPPTE----AGMAPAVVLHGDTHVQEQTRIVLDCGEDD 637
                     D +SPIVL LN SL  T       + P +                +CG D+
Sbjct: 722  -------IEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDN 774

Query: 638  VCVPQLQLTASVTGSP-LLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSN 696
            +C   L +T S      L+VG      + +   N+GE +Y  ++    P    Y R +S 
Sbjct: 775  ICQDDLSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSY-RKVST 833

Query: 697  VEGFE-----RLICNQKKENETRVVL----CELGNPM-KKNAQIGIAMLVSVGNLEEAGE 746
            ++        RL C      E    L    C + +P+  +N+++   +   V +    G 
Sbjct: 834  LQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGN 893

Query: 747  SVSFQLQIRSKNSQNPNSKIVL-LDVPVRAEAQVELRGNSFPASLV--VAAEEGEREQNS 803
             +  +  + S+N+    +K    L++PV+    + +  +      +   A+E   R    
Sbjct: 894  KLLLKANVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSR---- 949

Query: 804  LDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPV 863
                   ++H Y++ N G               +S P  L++++ ++             
Sbjct: 950  ------VMQHQYQVSNLGQ--------------RSLPISLVFLVPVRLN----------- 978

Query: 864  NPLKVDWGLP-IPSPSPIHPAHHKRDRRQIFLP-EPEQPSRLQDPVLVSCDSAPCTVVQC 921
                V W  P +     +    H ++R    LP   +  + L+   +V+C  A C  +QC
Sbjct: 979  --QTVIWDRPQVTFSENLSSTCHTKER----LPSHSDFLAELRKAPVVNCSIAVCQRIQC 1032

Query: 922  DLQEMARGQRAMVTV---LAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRG 978
            D+      +    T+   L+F W        L   V  +   FN S          LP  
Sbjct: 1033 DIPFFGIQEEFNATLKGNLSFDWYIKTSHNHL-LIVSTAEILFNDSVFTL------LPGQ 1085

Query: 979  EAQVWTQLLRALE--ERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKR 1026
             A V +Q    +E  E   P+  ++   +GGLLLL ++  A++K+GFFKR
Sbjct: 1086 GAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKR 1135


>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
          Length = 1188

 Score =  142 bits (359), Expect = 1e-33
 Identities = 212/899 (23%), Positives = 353/899 (39%), Gaps = 140/899 (15%)

Query: 188  ENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHV 247
            +N+ S+     + GFSS V + G L LGA G Y + G + +   A      R   L    
Sbjct: 357  KNETSFGLEMSQTGFSSHVVEDGVL-LGAVGAYDWNGAVLKETSAGKVIPLRESYL---- 411

Query: 248  SSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQR 307
              +    +  N   + GY   SV V    G +    YV GAP ++ T G V +   +  R
Sbjct: 412  --KEFPEELKNHGAYLGYTVTSV-VSSRQGRV----YVAGAPRFNHT-GKVILFTMHNNR 463

Query: 308  ---LHR-LRGEQMASYFGHSVAVTDVNGDGRHD-LLVGAPLYMESRADRKLAEVGRVYLF 362
               +H+ +RG+Q+ SYFG  +   D++GDG  D LLVGAP+Y     +R     G+VY++
Sbjct: 464  SLTIHQAMRGQQIGSYFGSEITSVDIDGDGVTDVLLVGAPMYFNEGRER-----GKVYVY 518

Query: 363  LQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLV 422
               +        +L  + +    RFGS+IA + DL++D YND+ V AP    +  G + +
Sbjct: 519  ELRQNLFVYNG-TLKDSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPL-EDNHAGAIYI 576

Query: 423  FLGQSEGLRSRPSQ-VLDSPFPTG-SAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYR 480
            F G    +   P Q +  S   TG   FG S+ G +D++++G  DL VGA G N V ++ 
Sbjct: 577  FHGFRGSILKTPKQRITASELATGLQYFGCSIHGQLDLNEDGLIDLAVGALG-NAVILW- 634

Query: 481  AQPVVKASVQLLVQDS-LNPAVKSCVLPQTKTPVSCFNIQMC--------------VGAT 525
            ++PVV+ +  L  + S +N   + C   ++    +C    +C              VG  
Sbjct: 635  SRPVVQINASLHFEPSKINIFHRDC--KRSGRDATCLAAFLCFTPIFLAPHFQTTTVGIR 692

Query: 526  GHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRD 585
             +    +        LD    R   R +LL S Q               +C      + D
Sbjct: 693  YNATMDERRYTPRAHLDEGGDRFTNRAVLLSSGQ--------------ELCERINFHVLD 738

Query: 586  EADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQL 645
             AD+   + P+  S+  SL   + G  P +     T ++        C ED+ CVP L L
Sbjct: 739  TADY---VKPVTFSVEYSLEDPDHG--PMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVL 793

Query: 646  TASVTGSPLLVGADNVLE----------------------------LQMDAANEGEGAYE 677
             A       +     VL                             ++    N GE AY 
Sbjct: 794  DARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYS 853

Query: 678  AELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVS 737
              L +       +   +   +    + C   +E   +  +C +  P  + A+  +A  + 
Sbjct: 854  TVLNISQSANLQFASLIQKEDSDGSIEC-VNEERRLQKQVCNVSYPFFR-AKAKVAFRLD 911

Query: 738  VGNLEEAGESV-----SFQLQIRSKNSQNPNSK---IVLLDVPVRAEAQVELRGNSFPAS 789
                 E  +S+       +L   S +++  ++K   +  L   ++ EA V    +S   S
Sbjct: 912  F----EFSKSIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHLKYEADVLFTRSS---S 964

Query: 790  LVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDI 849
            L     +        D  GP     + + N G   ++G+ + I +P  ++  + L     
Sbjct: 965  LSHYEVKPNSSLERYDGIGPPFSCIFRIQNLGLFPIHGMMMKITIPIATRSGNRLL---- 1020

Query: 850  QPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLV 909
                 L+ F     N     WG    + +   P   + D R+     P+      D V +
Sbjct: 1021 ----KLRDFLTDEANTSCNIWG----NSTEYRPTPVEEDLRR----APQLNHSNSDVVSI 1068

Query: 910  SCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYA 969
            +C+             +   Q     +L  LWL SL         +  +A        + 
Sbjct: 1069 NCNI-----------RLVPNQEINFHLLGNLWLRSLKALKYKSMKIMVNA---ALQRQFH 1114

Query: 970  VPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNR 1028
             P +      ++     +   E+  +PIW ++   LGGLLLL +LVLA+WK+GFF+  R
Sbjct: 1115 SPFIFREEDPSRQIVFEISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFRSAR 1173


>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
          Length = 1086

 Score =  140 bits (353), Expect = 6e-33
 Identities = 207/827 (25%), Positives = 340/827 (41%), Gaps = 143/827 (17%)

Query: 259  PEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDS-----YYQRLHRLRG 313
            PE   GY GY+V          T+    GAP +   +G V +        ++ ++  + G
Sbjct: 314  PEVRAGYLGYTVTW--LPSRQKTSLLASGAPRYQH-MGRVLLFQEPQGGGHWSQVQTIHG 370

Query: 314  EQMASYFGHSVAVTDVNGDGRHDLL-VGAPL-YMESRADRKLAEVGRVYLFLQPRGPHAL 371
             Q+ SYFG  +   DV+ DG  +LL +GAPL Y E R        GRV+++ + +    L
Sbjct: 371  TQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRG-------GRVFIYQRRQ----L 419

Query: 372  GAPSLL-LTGTQLY--GRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSE 428
            G   +  L G   Y  GRFG AI  L D++ DG  D+AV AP      +G V +F G+  
Sbjct: 420  GFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFNGRHG 476

Query: 429  GLRSRPSQVLDSPFPTGSA--FGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVK 486
            GL  +PSQ ++          FG S+ G  D++ +G  D+ VGA   +Q+ V  ++PVV 
Sbjct: 477  GLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSSRPVVD 534

Query: 487  ASVQLLVQDSLNPAVK-SCVLPQTKTPVSCFNIQMCVGATGHNIPQ-----KLSLNAELQ 540
                +    +  P  +  C    +       NI +C       IPQ       +L   LQ
Sbjct: 535  MVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKS-LIPQFQGRLVANLTYTLQ 593

Query: 541  LDRQKPRQ-----GRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSP 595
            LD  + R+     G R  L  +    T+++      H P+C             +D +SP
Sbjct: 594  LDGHRTRRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVC------------VQDLISP 641

Query: 596  IVLSLNVSLPPTE-------AGMAPAVVLHGDTHVQE-QTRIVLDCGEDDVCVPQLQLTA 647
            I +SLN SL   E       AG     +L    H +  +     +CGED  C   L+++ 
Sbjct: 642  INVSLNFSLWEEEGTPRDQRAGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSF 701

Query: 648  SVTGS-PLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRA-LSNVEGFERLIC 705
            S   S  L + A   L +++  +N  E AY  +L +H P G  + +  +        + C
Sbjct: 702  SPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSC 761

Query: 706  NQKKENE---TRVVLCELGNPM-KKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQN 761
             +  E     +R + C + +P+ K    + + M+ +       G+SV     +   N  +
Sbjct: 762  EELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDS 821

Query: 762  ----PNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPK---VEHT 814
                 NS   ++ +              +P ++++  +E      S    GPK   V+H 
Sbjct: 822  DLLEDNSATTIIPI-------------LYPINILIQDQEDSTLYVSFTPKGPKIHQVKHM 868

Query: 815  YELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPP-VNPLKVDWGLP 873
            Y++                   + QPS  ++  +I     +   PQPP   P+   W + 
Sbjct: 869  YQV-------------------RIQPS--IHDHNIPTLEAVVGVPQPPSEGPITHQWSVQ 907

Query: 874  IPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAM 933
            +  P P H    +R      LP+  +P              P  + +C    +   Q  +
Sbjct: 908  MEPPVPCHYEDLER------LPDAAEP------------CLPGALFRC---PVVFRQEIL 946

Query: 934  VTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLR--ALE 991
            V V+  L L    +     F L S    + +S  +      L    A +   +++   + 
Sbjct: 947  VQVIGTLELVGEIEAS-SMFSLCSSLSISFNSSKH----FHLYGSNASLAQVVMKVDVVY 1001

Query: 992  ERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEG 1038
            E+ +   +VL G+ GGLLLL ++ + ++KVGFFKRN   L+E  E G
Sbjct: 1002 EKQMLYLYVLSGI-GGLLLLLLIFIVLYKVGFFKRN---LKEKMEAG 1044


>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
          Length = 1170

 Score =  138 bits (348), Expect = 2e-32
 Identities = 206/828 (24%), Positives = 339/828 (40%), Gaps = 144/828 (17%)

Query: 259  PEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDS-----YYQRLHRLRG 313
            PE   GY GY+V          T+    GAP +   +G V +        ++ ++  + G
Sbjct: 397  PEVRAGYLGYTVTW--LPSRQKTSLLASGAPRYQH-MGRVLLFQEPQGGGHWSQVQTIHG 453

Query: 314  EQMASYFGHSVAVTDVNGDGRHDLL-VGAPL-YMESRADRKLAEVGRVYLFLQPRGPHAL 371
             Q+ SYFG  +   DV+ DG  +LL +GAPL Y E R        GRV+++ + +    L
Sbjct: 454  TQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRG-------GRVFIYQRRQ----L 502

Query: 372  GAPSLL-LTGTQLY--GRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSE 428
            G   +  L G   Y  GRFG AI  L D++ DG  D+AV AP      +G V +F G+  
Sbjct: 503  GFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFNGRHG 559

Query: 429  GLRSRPSQVLDSPFPTGSA--FGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVK 486
            GL  +PSQ ++          FG S+ G  D++ +G  D+ VGA   +Q+ V  ++PVV 
Sbjct: 560  GLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSSRPVVD 617

Query: 487  ASVQLLVQDSLNPAVK-SCVLPQTKTPVSCFNIQMCVGATGHNIPQ-----KLSLNAELQ 540
                +    +  P  +  C    +       NI +C       IPQ       +L   LQ
Sbjct: 618  MVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKS-LIPQFQGRLVANLTYTLQ 676

Query: 541  LDRQKPRQ-----GRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSP 595
            LD  + R+     G R  L  +    T+++      H P+C             +D +SP
Sbjct: 677  LDGHRTRRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVC------------VQDLISP 724

Query: 596  IVLSLNVSLPPTEA--------GMAPAVVLHGDTHVQE-QTRIVLDCGEDDVCVPQLQLT 646
            I +SLN SL   E         G     +L    H +  +     +CGED  C   L+++
Sbjct: 725  INVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVS 784

Query: 647  ASVTGS-PLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRA-LSNVEGFERLI 704
             S   S  L + A   L +++  +N  E AY  +L +H P G  + +  +        + 
Sbjct: 785  FSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVS 844

Query: 705  CNQKKENE---TRVVLCELGNPM-KKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQ 760
            C +  E     +R + C + +P+ K    + + M+ +       G+SV     +   N  
Sbjct: 845  CEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNED 904

Query: 761  N----PNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPK---VEH 813
            +     NS   ++ +              +P ++++  +E      S    GPK   V+H
Sbjct: 905  SDLLEDNSATTIIPI-------------LYPINILIQDQEDSTLYVSFTPKGPKIHQVKH 951

Query: 814  TYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPP-VNPLKVDWGL 872
             Y++                   + QPS  ++  +I     +   PQPP   P+   W +
Sbjct: 952  MYQV-------------------RIQPS--IHDHNIPTLEAVVGVPQPPSEGPITHQWSV 990

Query: 873  PIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRA 932
             +  P P H    +R      LP+  +P              P  + +C    +   Q  
Sbjct: 991  QMEPPVPCHYEDLER------LPDAAEP------------CLPGALFRC---PVVFRQEI 1029

Query: 933  MVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLR--AL 990
            +V V+  L L    +     F L S    + +S  +      L    A +   +++   +
Sbjct: 1030 LVQVIGTLELVGEIEAS-SMFSLCSSLSISFNSSKH----FHLYGSNASLAQVVMKVDVV 1084

Query: 991  EERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEG 1038
             E+ +   +VL G+ GGLLLL ++ + ++KVGFFKRN   L+E  E G
Sbjct: 1085 YEKQMLYLYVLSGI-GGLLLLLLIFIVLYKVGFFKRN---LKEKMEAG 1128


>gi|148728188 integrin, alpha E precursor [Homo sapiens]
          Length = 1179

 Score =  130 bits (326), Expect = 8e-30
 Identities = 155/577 (26%), Positives = 249/577 (43%), Gaps = 82/577 (14%)

Query: 199 EAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSF---- 254
           + GFS+ +    +++LGA G + + G                G LL+   S+   F    
Sbjct: 403 QIGFSAQILDERQVLLGAVGAFDWSG----------------GALLYDTRSRRGRFLNQT 446

Query: 255 -----DSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQR-- 307
                D+   +Y   Y GY+VAV      L+   Y+ GAP +       E+     +   
Sbjct: 447 AAAAADAEAAQY--SYLGYAVAVLHKTCSLS---YIAGAPRYKHHGAVFELQKEGREASF 501

Query: 308 LHRLRGEQMASYFGHSVAVTDVNGDGRHD-LLVGAPLYMESRADRKLAEVGRVYLFLQPR 366
           L  L GEQM SYFG  +   D++ DG  D LLV AP Y          E GRVY++   R
Sbjct: 502 LPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVH------GEEGRVYVY---R 552

Query: 367 GPHALGAPSL--LLTGTQLY--GRFGSAIAPLGDLDRDGYNDIAVAAP---YGGPSGR-- 417
                G+ SL  +L+G   +   RFG A+A +GDL +D   D+A+ AP   +G   G   
Sbjct: 553 LSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASF 612

Query: 418 GQVLVFLGQSEGLRSRPSQVL--DSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQ 475
           G V ++ G  +GL + PSQ +   +  P    FG S+ G  DI  +G  D+ VG  G  Q
Sbjct: 613 GSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLG--Q 670

Query: 476 VAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSL 535
             V+R++PVV+  V +    S  P   + V+        CF I     A+   + + L L
Sbjct: 671 AVVFRSRPVVRLKVSMAFTPSALPIGFNGVV----NVRLCFEISSVTTASESGLREAL-L 725

Query: 536 NAELQLDRQKPRQGRR-------VLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEAD 588
           N  L +D  K R+  +       +  L    +G+ L  DL      +   T   L +E  
Sbjct: 726 NFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDL------LLMPTEGELCEEDC 779

Query: 589 FRDKLSPIVLSLNVSLPPTEAG-MAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTA 647
           F +  + + +S  +  P  +     P +  + +     Q      C     CV +LQL  
Sbjct: 780 FSN--ASVKVSYQLQTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLAT 837

Query: 648 SVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQ 707
           +V+   L+VG    L L ++  N GE +Y   +A++ P+     R          + C+ 
Sbjct: 838 TVSQQELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQLKRMQKPPS--PNIQCDD 895

Query: 708 KKENETRVVL-CELGNPMKKNAQIGIAMLVSVGNLEE 743
            +   + +++ C +G+P+ K +   +++   V  LEE
Sbjct: 896 PQPVASVLIMNCRIGHPVLKRSSAHVSV---VWQLEE 929



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 16/54 (29%), Positives = 33/54 (61%), Gaps = 2/54 (3%)

Query: 973  LSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKR 1026
            L+      ++    L+  +  ++PI  ++ G +GGLL+L ++++ ++K GFFKR
Sbjct: 1103 LNAENHRTKITVVFLKDEKYHSLPI--IIKGSVGGLLVLIVILVILFKCGFFKR 1154


>gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo
            sapiens]
          Length = 462

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 92/439 (20%), Positives = 172/439 (39%), Gaps = 51/439 (11%)

Query: 632  DCGEDDVCVPQLQLTASVTG-SPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHY 690
            +CG D +C   L ++ S  G   LLVG++  L  ++   N+GE +Y   +    P G  Y
Sbjct: 19   NCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGLSY 78

Query: 691  MRALSNVEGFE----RLICNQKKENE--TRVVLCELGNPM-KKNAQIGIAMLVSVGNLEE 743
                   +  +     L C+        T    C + + + +  AQI       V     
Sbjct: 79   RYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAV 138

Query: 744  AGESVSFQLQIRSKNSQNPNSKIVL-LDVPVRAEAQVELRGNSFPASLVVAAEEGEREQN 802
             G+ +     + S+N+    SK    L++PV+      +  +      +  +E  E+E +
Sbjct: 139  LGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVSSHEQFTKYLNFSESEEKESH 198

Query: 803  SLDSWGPKVEHTYELHNNGPGTVNGLH--------LSIHLPGQSQPSDLLYILDIQ---P 851
                      H Y+      G   G++        +SI+     + +     +D++   P
Sbjct: 199  V-------AMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQEAVWMDVEVSHP 251

Query: 852  QGGLQCFPQPPVNPLKVD-----WGLPIPSPS------PIHPAHHKRDRRQIFLPEPEQP 900
            Q    C       P  +D     W   +P+ +      P +P+  +    +I  P  +  
Sbjct: 252  QVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSL-RCSSEKIAPPASDFL 310

Query: 901  SRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTV---LAFLWLPSLYQRPLDQFVLQS 957
            + +Q   ++ C  A C   +CD+   +  +    T+   L+F W+  + Q+ +    + S
Sbjct: 311  AHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKVS---VVS 367

Query: 958  HAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAI--PIWWVLVGVLGGLLLLTILV 1015
             A     +  Y+     LP  EA +  Q    LE+  +  P   ++   +GGLLLL ++ 
Sbjct: 368  VAEITFDTSVYS----QLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLALIT 423

Query: 1016 LAMWKVGFFKRNRPPLEED 1034
              ++KVGFFKR    + E+
Sbjct: 424  AVLYKVGFFKRQYKEMMEE 442


>gi|29171717 glycosylphosphatidylinositol specific phospholipase D1
           isoform 1 precursor [Homo sapiens]
          Length = 840

 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 70/248 (28%), Positives = 103/248 (41%), Gaps = 35/248 (14%)

Query: 246 HVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWT----------- 294
           HVSS   S+  S P Y    W  + A    DG     + VVGAP +S             
Sbjct: 364 HVSSPLASYFLSFP-YARLGWAMTSADLNQDGH---GDLVVGAPGYSRPGHIHIGRVYLI 419

Query: 295 ----LGAVEILDSYYQRLHR-LRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRA 349
               LG   +     +  HR L G Q +  FG ++AV D N DG  DL VGAP    S  
Sbjct: 420 YGNDLGLPPVDLDLDKEAHRILEGFQPSGRFGSALAVLDFNVDGVPDLAVGAP----SVG 475

Query: 350 DRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAA 409
             +L   G VY++   +      +P++ ++   +Y   G  +    D++ D   D+ + +
Sbjct: 476 SEQLTYKGAVYVYFGSKQGGMSSSPNITISCQDIYCNLGWTLL-AADVNGDSEPDLVIGS 534

Query: 410 PY--GGPSGRGQVLVF-----LGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNG 462
           P+  GG   +G V  F     L   E L    +          S FG+SL G V +D+  
Sbjct: 535 PFAPGGGKQKGIVAAFYSGPSLSDKEKLNVEAANWTVRGEEDFSWFGYSLHG-VTVDNRT 593

Query: 463 YPDLIVGA 470
              L+VG+
Sbjct: 594 L--LLVGS 599



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 105/423 (24%), Positives = 163/423 (38%), Gaps = 86/423 (20%)

Query: 53  SLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGS 112
           S D ++D HG   +VVGAP    P     G V+L      G   P +  DL  E   +  
Sbjct: 387 SADLNQDGHGD--LVVGAPGYSRPGHIHIGRVYLIYGNDLG--LPPVDLDLDKEAHRI-- 440

Query: 113 QTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTP-VGSCFLAQPESGRR 171
             L+ F+     G+++               +NV    + A   P VGS  L   +    
Sbjct: 441 --LEGFQPSGRFGSALAVLD-----------FNVDGVPDLAVGAPSVGSEQLTY-KGAVY 486

Query: 172 AEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAG-----ELVLG---APGGYYFL 223
             +   +G   S   +    S    YC  G++ +          +LV+G   APGG    
Sbjct: 487 VYFGSKQGGMSSSPNIT--ISCQDIYCNLGWTLLAADVNGDSEPDLVIGSPFAPGGGKQK 544

Query: 224 GLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTE 283
           G++A        S          ++ ++ ++     E F  ++GYS+     D   N T 
Sbjct: 545 GIVAAFYSGPSLSDKEK------LNVEAANWTVRGEEDFS-WFGYSLHGVTVD---NRTL 594

Query: 284 YVVGAPTWSWTLGAVEILD------------SYY----QRLHRLRGEQMASYFGHSVAVT 327
            +VG+PTW        +L              Y+    Q    + G++     G S++  
Sbjct: 595 LLVGSPTWKNASRLGHLLHIRDEKKSLGRVYGYFPPNGQSWFTISGDKAMGKLGTSLSSG 654

Query: 328 DV--NGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGA------PSLLLT 379
            V  NG  +  LLVGAP Y +      +++V  + + L   G   + A      P LL T
Sbjct: 655 HVLMNGTLKQVLLVGAPTYDD------VSKVAFLTVTLHQGGATRMYALTSDAQPLLLST 708

Query: 380 --GTQLYGRFGSAIAPLGDLDRDGYNDIAVAAP----------YGGPSGRGQVLVFLGQS 427
             G + + RFG  +  L DLD DG ++I +AAP           GG  GR  V V+ G+ 
Sbjct: 709 FSGDRRFSRFGGVLH-LSDLDDDGLDEIIMAAPLRIADVTSGLIGGEDGR--VYVYNGKE 765

Query: 428 EGL 430
             L
Sbjct: 766 TTL 768


>gi|153945755 zinc finger protein 608 [Homo sapiens]
          Length = 1512

 Score = 34.7 bits (78), Expect = 0.48
 Identities = 34/110 (30%), Positives = 50/110 (45%), Gaps = 26/110 (23%)

Query: 346 ESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDG---- 401
           ESR     AE  +VY F       ++G+ S L   T + G+  + +APL  L ++G    
Sbjct: 873 ESRMASIKAEADKVYTFTDNAPSPSIGSASRLECSTLVNGQ--APMAPLHVLTQNGAESS 930

Query: 402 --------YNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSR---PSQVLDS 440
                   Y+DI+ AA  GG   R         SEG+RS+   PS ++ S
Sbjct: 931 AAKTSSPAYSDISDAADDGGSDSR---------SEGMRSKASSPSDIISS 971


>gi|31652264 RNA binding motif protein 26 [Homo sapiens]
          Length = 980

 Score = 34.7 bits (78), Expect = 0.48
 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 8/102 (7%)

Query: 818 HNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPV-NPLKVDWGLPIPS 876
           H + P  V  ++L   LP  +QP     +++  P  GL   P PP+  P  V+   P+P 
Sbjct: 313 HGSDPVVVEDVNLPGMLPFPAQPP----VVEGPPPPGLP--PPPPILTPPPVNLRPPVPP 366

Query: 877 PSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTV 918
           P P+ P+          LP P QPS +  P   +  S P  V
Sbjct: 367 PGPLPPSLPPVTGPPPPLP-PLQPSGMDAPPNSATSSVPTVV 407


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,257,165
Number of Sequences: 37866
Number of extensions: 2292738
Number of successful extensions: 5557
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 5181
Number of HSP's gapped (non-prelim): 97
length of query: 1039
length of database: 18,247,518
effective HSP length: 112
effective length of query: 927
effective length of database: 14,006,526
effective search space: 12984049602
effective search space used: 12984049602
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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