BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] (1039 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] 2115 0.0 gi|49170034 integrin, alpha 8 [Homo sapiens] 709 0.0 gi|56237029 integrin alpha 5 precursor [Homo sapiens] 649 0.0 gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] 630 e-180 gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] 604 e-172 gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] 590 e-168 gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] 287 4e-77 gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] 282 1e-75 gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] 269 1e-71 gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] 267 4e-71 gi|52485941 integrin, alpha 9 precursor [Homo sapiens] 249 1e-65 gi|67191027 integrin alpha 4 precursor [Homo sapiens] 248 2e-65 gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] 246 8e-65 gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [... 236 8e-62 gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [... 235 1e-61 gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 187 3e-47 gi|62548866 integrin, alpha D precursor [Homo sapiens] 170 6e-42 gi|116295258 integrin alpha 2 precursor [Homo sapiens] 169 2e-41 gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 156 8e-38 gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 149 1e-35 gi|34452173 integrin alpha X precursor [Homo sapiens] 145 1e-34 gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 145 2e-34 gi|52485853 integrin, alpha 11 precursor [Homo sapiens] 142 1e-33 gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 140 6e-33 gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 138 2e-32 gi|148728188 integrin, alpha E precursor [Homo sapiens] 130 8e-30 gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ... 60 1e-08 gi|29171717 glycosylphosphatidylinositol specific phospholipase ... 54 6e-07 gi|153945755 zinc finger protein 608 [Homo sapiens] 35 0.48 gi|31652264 RNA binding motif protein 26 [Homo sapiens] 35 0.48 >gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] Length = 1039 Score = 2115 bits (5479), Expect = 0.0 Identities = 1039/1039 (100%), Positives = 1039/1039 (100%) Query: 1 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDS 60 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDS Sbjct: 1 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDS 60 Query: 61 HGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKA 120 HGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKA Sbjct: 61 HGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKA 120 Query: 121 RQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGN 180 RQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGN Sbjct: 121 RQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGN 180 Query: 181 TLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRP 240 TLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRP Sbjct: 181 TLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRP 240 Query: 241 GILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEI 300 GILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEI Sbjct: 241 GILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEI 300 Query: 301 LDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVY 360 LDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVY Sbjct: 301 LDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVY 360 Query: 361 LFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQV 420 LFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQV Sbjct: 361 LFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQV 420 Query: 421 LVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYR 480 LVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYR Sbjct: 421 LVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYR 480 Query: 481 AQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQ 540 AQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQ Sbjct: 481 AQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQ 540 Query: 541 LDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSL 600 LDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSL Sbjct: 541 LDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSL 600 Query: 601 NVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADN 660 NVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADN Sbjct: 601 NVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADN 660 Query: 661 VLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCEL 720 VLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCEL Sbjct: 661 VLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCEL 720 Query: 721 GNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVE 780 GNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVE Sbjct: 721 GNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVE 780 Query: 781 LRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQP 840 LRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQP Sbjct: 781 LRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQP 840 Query: 841 SDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQP 900 SDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQP Sbjct: 841 SDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQP 900 Query: 901 SRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAW 960 SRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAW Sbjct: 901 SRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAW 960 Query: 961 FNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWK 1020 FNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWK Sbjct: 961 FNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWK 1020 Query: 1021 VGFFKRNRPPLEEDDEEGE 1039 VGFFKRNRPPLEEDDEEGE Sbjct: 1021 VGFFKRNRPPLEEDDEEGE 1039 >gi|49170034 integrin, alpha 8 [Homo sapiens] Length = 1063 Score = 709 bits (1830), Expect = 0.0 Identities = 421/1061 (39%), Positives = 599/1061 (56%), Gaps = 57/1061 (5%) Query: 1 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDS 60 +A C AL +L W +P A NLD +LT Y+GP GS FG+++DFH Sbjct: 17 IAPLCCAAAALGMLLW---------SPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPD 67 Query: 61 HGRVAIVVGAPR--TLGPSQEETGGVFLCPWRAEGG-QCPSLLFDLRD--ETRNVGSQTL 115 +++VGAP+ T P E G V+ CPW AEG QC + FD + + R G++ Sbjct: 68 ARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKEP 127 Query: 116 QTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYS 175 FK+ Q GA+V + +VACAP HW L+ T E K PVG+C++A AE+S Sbjct: 128 IEFKSNQWFGATVKAHKGKVVACAPLYHWRTLKPTPE--KDPVGTCYVAIQNFSAYAEFS 185 Query: 176 PCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIF 235 PCR + N + YC+AGFS + G+L++G PG +Y+ G + A VADI Sbjct: 186 PCRNS--------NADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADII 237 Query: 236 SSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTL 295 ++Y +L ++ + + + + Y D Y GYSVA GEF GD + E V G P + Sbjct: 238 ANYSFKDILRKLAGEKQT-EVAPASYDDSYLGYSVAAGEFTGD-SQQELVAGIPRGAQNF 295 Query: 296 GAVEILDSYYQR-LHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLA 354 G V I++S + GEQMASYFG++V V+DVN DG D+LVGAPL+ME + Sbjct: 296 GYVSIINSTDMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPR 355 Query: 355 EVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGP 414 EVG++YL+LQ L +LTGT+ +GRFGSA+A LGDL++DGYNDIA+ P+ G Sbjct: 356 EVGQIYLYLQVSS--LLFRDPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGK 413 Query: 415 SGRGQVLVFLGQSEGLRSRPSQVLDSPFPTG---SAFGFSLRGAVDIDDNGYPDLIVGAY 471 RG+VL++ G +GL ++PSQVL + + S FGF+LRG DID N YPDLIVGA+ Sbjct: 414 DQRGKVLIYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAF 473 Query: 472 GANQVAVYRAQPVVKASVQLLVQDSL-NPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIP 530 G +VAVYRA+PVV QLL+ + N K+C +P + T +CF++++C TG +I Sbjct: 474 GTGKVAVYRARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIA 533 Query: 531 QKLSLNAELQLDRQKPRQG-RRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADF 589 + L AE+QLD K + +R L L + QA L + + S C + +LRDE +F Sbjct: 534 NTIVLMAEVQLDSLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEF 593 Query: 590 RDKLSPIVLSLNVSLPPTE----AGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQL 645 RDKLSPI +SLN SL + + P + + + V EQ I++DCGED++CVP L+L Sbjct: 594 RDKLSPINISLNYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKL 653 Query: 646 TASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLIC 705 +A +++G +N L L ++A NEGEGAYEAEL V +P+ A Y+ N +GF L C Sbjct: 654 SARPDKHQVIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSC 713 Query: 706 NQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSK 765 K EN TR+V+C+LGNPM + + +V LE+ S++F LQIRS N NP+S Sbjct: 714 EYKMENVTRMVVCDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSN 773 Query: 766 IVLLDVPVRAEAQVELRGNSFPASLVVAAE--EGEREQNSLDSWGPKVEHTYELHNNGPG 823 V L + + A AQVE+RG S P +V+ E E E + + GP VEH YELHN GP Sbjct: 774 FVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPS 833 Query: 824 TVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPI--- 880 T++ L + P ++ LLYI IQ G LQC P P +NP + P SP Sbjct: 834 TISDTILEVGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIK---PAASPEDTPEL 890 Query: 881 ------HPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMV 934 H +R + + E + S + +++C + C + C + + G+ A++ Sbjct: 891 SAFLRNSTIPHLVRKRDVHVVEFHRQSPAK---ILNCTNIECLQISCAVGRLEGGESAVL 947 Query: 935 TVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALE--E 992 V + LW + QR D + L S F V +PY P LP G + T ++ A Sbjct: 948 KVRSRLWAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVS 1007 Query: 993 RAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEE 1033 +IP+W +++ +L GLL+L IL LA+WK GFF R RPP E+ Sbjct: 1008 FSIPLWVIILAILLGLLVLAILTLALWKCGFFDRARPPQED 1048 >gi|56237029 integrin alpha 5 precursor [Homo sapiens] Length = 1049 Score = 649 bits (1675), Expect = 0.0 Identities = 404/1046 (38%), Positives = 577/1046 (55%), Gaps = 68/1046 (6%) Query: 13 LLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPR 72 LL +LLLL P P NLD +GP GS FGFS++F++ V+++VGAP+ Sbjct: 25 LLPLLLLLLPP--PPRVGGFNLDAEAPAVLSGPPGSFFGFSVEFYRPGTDGVSVLVGAPK 82 Query: 73 --TLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDE-------TRNVGSQTLQTFKARQG 123 T P + G V+LCPW A QC + FD + + + G + ++ +K+ Q Sbjct: 83 ANTSQPGVLQGGAVYLCPWGASPTQCTPIEFDSKGSRLLESSLSSSEGEEPVE-YKSLQW 141 Query: 124 LGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLS 183 GA+V + I+ACAP W +E PVG+C+L+ R EY+PCR Sbjct: 142 FGATVRAHGSSILACAPLYSWRT---EKEPLSDPVGTCYLSTDNFTRILEYAPCR----- 193 Query: 184 RIYVENDFSW--DKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPG 241 +DFSW + YC+ GFS+ T+ G +VLG PG Y++ G + A I SY P Sbjct: 194 -----SDFSWAAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIAESYYPE 248 Query: 242 ILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL 301 L+ V Q L ++ Y D Y GYSVAVGEF GD +T ++V G P + T G V IL Sbjct: 249 YLINLVQGQ-LQTRQASSIYDDSYLGYSVAVGEFSGD-DTEDFVAGVPKGNLTYGYVTIL 306 Query: 302 D-SYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVY 360 + S + L+ GEQMASYFG++VA TDVNGDG DLLVGAPL M+ D + EVGRVY Sbjct: 307 NGSDIRSLYNFSGEQMASYFGYAVAATDVNGDGLDDLLVGAPLLMDRTPDGRPQEVGRVY 366 Query: 361 LFLQPRGPHALG---APSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGR 417 ++LQ H G P+L LTG +GRFGS++ PLGDLD+DGYND+A+ AP+GG + + Sbjct: 367 VYLQ----HPAGIEPTPTLTLTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQ 422 Query: 418 GQVLVFLGQSEGLRSRPSQVLD---SPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGAN 474 G V VF G GL S+PSQVL + T FG +LRG D+D NGYPDLIVG++G + Sbjct: 423 GVVFVFPGGPGGLGSKPSQVLQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVD 482 Query: 475 QVAVYRAQPVVKASVQLLVQDSL-NPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKL 533 + VYR +P+V AS L + ++ NP +SC L PV+C N+ C+ A+G ++ + Sbjct: 483 KAVVYRGRPIVSASASLTIFPAMFNPEERSCSL--EGNPVACINLSFCLNASGKHVADSI 540 Query: 534 SLNAELQLDRQKPRQG-RRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDK 592 ELQLD QK + G RR L L S+QA T L + C +LR+E++FRDK Sbjct: 541 GFTVELQLDWQKQKGGVRRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRDK 600 Query: 593 LSPIVLSLNVSLPP----TEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTAS 648 LSPI ++LN SL P G+ PA+ + ++++ +I+LDCGED++CVP LQL Sbjct: 601 LSPIHIALNFSLDPQAPVDSHGLRPALHYQSKSRIEDKAQILLDCGEDNICVPDLQLEVF 660 Query: 649 VTGSPLLVGADNVLELQMDAANEGE-GAYEAELAVHLPQGAHYMRALSNVEGFERLICNQ 707 + + +G N L L A N GE GAYEAEL V P A Y + + F L C+ Sbjct: 661 GEQNHVYLGDKNALNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGLVRHPGNFSSLSCDY 720 Query: 708 KKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIV 767 N++R+++C+LGNPMK A + + +V +L + +++ F QI SKN N S +V Sbjct: 721 FAVNQSRLLVCDLGNPMKAGASLWGGLRFTVPHLRDTKKTIQFDFQILSKNLNNSQSDVV 780 Query: 768 LLDVPVRAEAQVELRGNSFP-ASLVVAAEEGEREQ-NSLDSWGPKVEHTYELHNNGPGTV 825 + V A+AQV L G S P A L ++ R+Q + GP V H YEL N GP ++ Sbjct: 781 SFRLSVEAQAQVTLNGVSKPEAVLFPVSDWHPRDQPQKEEDLGPAVHHVYELINQGPSSI 840 Query: 826 NGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHH 885 + L + P + LLY+ + GL C P+NP GL + P HH Sbjct: 841 SQGVLELSCPQALEGQQLLYVTRVT---GLNCTTNHPINPK----GLEL---DPEGSLHH 890 Query: 886 KRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSL 945 ++ R P + S P ++ C A C ++C+L + + + + + +W + Sbjct: 891 QQKRE-----APSRSSASSGPQILKCPEAECFRLRCELGPLHQQESQSLQLHFRVWAKTF 945 Query: 946 YQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWT--QLLRALEERAIPIWWVLVG 1003 QR F LQ A + +PY + P LP+ E QV T Q +A +P+W +++ Sbjct: 946 LQREHQPFSLQCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLWIIILA 1005 Query: 1004 VLGGLLLLTILVLAMWKVGFFKRNRP 1029 +L GLLLL +L+ ++K+GFFKR+ P Sbjct: 1006 ILFGLLLLGLLIYILYKLGFFKRSLP 1031 >gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] Length = 1048 Score = 630 bits (1624), Expect = e-180 Identities = 399/1045 (38%), Positives = 569/1045 (54%), Gaps = 54/1045 (5%) Query: 19 LLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDS-HGRVAIVVGAPR--TLG 75 LLL P A NLD Y+GP GS FGF++DF S R+ ++VGAP+ T Sbjct: 18 LLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQ 77 Query: 76 PSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVI 135 P E G V C W + +C + FD L+ FK+ Q GASV S D I Sbjct: 78 PGIVEGGQVLKCDWSSTR-RCQPIEFDATGNRDYAKDDPLE-FKSHQWFGASVRSKQDKI 135 Query: 136 VACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDK 195 +ACAP HW K E + PVG+CFL + + EY+PCR + + + Sbjct: 136 LACAPLYHWRTEMKQE---REPVGTCFLQ--DGTKTVEYAPCRSQDID--------ADGQ 182 Query: 196 RYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFD 255 +C+ GFS T+A ++LG PG +Y+ G L VA+I S Y P + ++Q L+ Sbjct: 183 GFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQ-LATR 241 Query: 256 SSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSY-YQRLHRLRGE 314 ++ + D Y GYSVAVG+F+GD ++V G P + TLG V I D L+ GE Sbjct: 242 TAQAIFDDSYLGYSVAVGDFNGD-GIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE 300 Query: 315 QMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGA- 373 QMA+YFG SVA TD+NGD D+ +GAPL+M+ +D KL EVG+V + LQ A G Sbjct: 301 QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQ----RASGDF 356 Query: 374 PSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSR 433 + L G +++ RFGSAIAPLGDLD+DG+NDIA+AAPYGG +G V +F G+S GL + Sbjct: 357 QTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAV 416 Query: 434 PSQVLDSPFPTGS---AFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQ 490 PSQ+L+ + S +FG+S++GA DID NGYPDLIVGA+G ++ +YRA+PV+ + Sbjct: 417 PSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAG 476 Query: 491 LLVQDS-LNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNI-PQKLSLNAELQLDRQKPRQ 548 L V S LN K+C LP T VSCFN++ C+ A G + P+KL+ EL LD+ K + Sbjct: 477 LEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKG 536 Query: 549 G-RRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPT 607 RR L L S+ + N+ + C +A+LRDE++FRDKL+PI + + L Sbjct: 537 AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYR 596 Query: 608 EA----GMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLE 663 A G+ P + ++ Q I+LDCGED+VC P+L+++ + +G DN L Sbjct: 597 TAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLT 656 Query: 664 LQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNP 723 L + A N+GEGAYEAEL V +P A ++ + N E RL C K EN+TR V+C+LGNP Sbjct: 657 LIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNP 716 Query: 724 MKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRG 783 MK Q+ + SV E SV F LQI+S N + S +V V + A VE+RG Sbjct: 717 MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRG 776 Query: 784 NSFPASLVVAAEEGEREQN--SLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPS 841 S P + + E ++N + + GP V+H YEL NNGP + + L + P + + Sbjct: 777 VSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNN 836 Query: 842 DLLYILDIQPQGGLQCFPQPPVNPLKVD-WGLPIPSPSPIHPAHHKRD----RRQIFLPE 896 LLYIL G + C +NPL++ L + +RD +R + L E Sbjct: 837 TLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSE 896 Query: 897 PEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLD--QFV 954 D + C A C + C + + RG+ A++ V + LW + + + Sbjct: 897 -------GDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYS 949 Query: 955 LQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALE--ERAIPIWWVLVGVLGGLLLLT 1012 L+S A FNV PY P+ V T + ++ +P+W +++ VL GLLLL Sbjct: 950 LKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLA 1009 Query: 1013 ILVLAMWKVGFFKRNRPPLEEDDEE 1037 +LV M+++GFFKR RPP EE + E Sbjct: 1010 VLVFVMYRMGFFKRVRPPQEEQERE 1034 >gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] Length = 1002 Score = 604 bits (1558), Expect = e-172 Identities = 380/1000 (38%), Positives = 547/1000 (54%), Gaps = 53/1000 (5%) Query: 63 RVAIVVGAPR--TLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKA 120 R+ ++VGAP+ T P E G V C W + +C + FD L+ FK+ Sbjct: 17 RMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTR-RCQPIEFDATGNRDYAKDDPLE-FKS 74 Query: 121 RQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGN 180 Q GASV S D I+ACAP HW K E + PVG+CFL + + EY+PCR Sbjct: 75 HQWFGASVRSKQDKILACAPLYHWRTEMKQE---REPVGTCFLQ--DGTKTVEYAPCRSQ 129 Query: 181 TLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRP 240 + + + +C+ GFS T+A ++LG PG +Y+ G L VA+I S Y P Sbjct: 130 DID--------ADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDP 181 Query: 241 GILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEI 300 + ++Q L+ ++ + D Y GYSVAVG+F+GD ++V G P + TLG V I Sbjct: 182 NVYSIKYNNQ-LATRTAQAIFDDSYLGYSVAVGDFNGD-GIDDFVSGVPRAARTLGMVYI 239 Query: 301 LDSY-YQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRV 359 D L+ GEQMA+YFG SVA TD+NGD D+ +GAPL+M+ +D KL EVG+V Sbjct: 240 YDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQV 299 Query: 360 YLFLQPRGPHALGA-PSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRG 418 + LQ A G + L G +++ RFGSAIAPLGDLD+DG+NDIA+AAPYGG +G Sbjct: 300 SVSLQ----RASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKG 355 Query: 419 QVLVFLGQSEGLRSRPSQVLDSPFPTGS---AFGFSLRGAVDIDDNGYPDLIVGAYGANQ 475 V +F G+S GL + PSQ+L+ + S +FG+S++GA DID NGYPDLIVGA+G ++ Sbjct: 356 IVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDR 415 Query: 476 VAVYRAQPVVKASVQLLVQDS-LNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNI-PQKL 533 +YRA+PV+ + L V S LN K+C LP T VSCFN++ C+ A G + P+KL Sbjct: 416 AILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKL 475 Query: 534 SLNAELQLDRQKPRQG-RRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDK 592 + EL LD+ K + RR L L S+ + N+ + C +A+LRDE++FRDK Sbjct: 476 NFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDK 535 Query: 593 LSPIVLSLNVSLPPTEA----GMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTAS 648 L+PI + + L A G+ P + ++ Q I+LDCGED+VC P+L+++ Sbjct: 536 LTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD 595 Query: 649 VTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQK 708 + +G DN L L + A N+GEGAYEAEL V +P A ++ + N E RL C K Sbjct: 596 SDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFK 655 Query: 709 KENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVL 768 EN+TR V+C+LGNPMK Q+ + SV E SV F LQI+S N + S +V Sbjct: 656 TENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVS 715 Query: 769 LDVPVRAEAQVELRGNSFPASLVVAAEEGEREQN--SLDSWGPKVEHTYELHNNGPGTVN 826 V + A VE+RG S P + + E ++N + + GP V+H YEL NNGP + + Sbjct: 716 HKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFS 775 Query: 827 GLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVD-WGLPIPSPSPIHPAHH 885 L + P + + LLYIL G + C +NPL++ L + Sbjct: 776 KAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQG 835 Query: 886 KRD----RRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLW 941 +RD +R + L E D + C A C + C + + RG+ A++ V + LW Sbjct: 836 ERDHLITKRDLALSE-------GDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLW 888 Query: 942 LPSLYQRPLD--QFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALE--ERAIPI 997 + + + L+S A FNV PY P+ V T + ++ +P+ Sbjct: 889 TETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPV 948 Query: 998 WWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEE 1037 W +++ VL GLLLL +LV M+++GFFKR RPP EE + E Sbjct: 949 WVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQERE 988 >gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] Length = 1012 Score = 590 bits (1520), Expect = e-168 Identities = 387/1045 (37%), Positives = 547/1045 (52%), Gaps = 90/1045 (8%) Query: 19 LLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDS-HGRVAIVVGAPR--TLG 75 LLL P A NLD Y+GP GS FGF++DF S R+ ++VGAP+ T Sbjct: 18 LLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQ 77 Query: 76 PSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVI 135 P E G V C W + +C + FD L+ FK+ Q GASV S D I Sbjct: 78 PGIVEGGQVLKCDWSSTR-RCQPIEFDATGNRDYAKDDPLE-FKSHQWFGASVRSKQDKI 135 Query: 136 VACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDK 195 +ACAP HW K E + PVG+CFL + + EY+PCR L Sbjct: 136 LACAPLYHWRTEMKQE---REPVGTCFLQ--DGTKTVEYAPCRSRQL------------- 177 Query: 196 RYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFD 255 VA+I S Y P + ++Q L+ Sbjct: 178 -------------------------------ISDQVAEIVSKYDPNVYSIKYNNQ-LATR 205 Query: 256 SSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSY-YQRLHRLRGE 314 ++ + D Y GYSVAVG+F+GD ++V G P + TLG V I D L+ GE Sbjct: 206 TAQAIFDDSYLGYSVAVGDFNGD-GIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE 264 Query: 315 QMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGA- 373 QMA+YFG SVA TD+NGD D+ +GAPL+M+ +D KL EVG+V + LQ A G Sbjct: 265 QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQ----RASGDF 320 Query: 374 PSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSR 433 + L G +++ RFGSAIAPLGDLD+DG+NDIA+AAPYGG +G V +F G+S GL + Sbjct: 321 QTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAV 380 Query: 434 PSQVLDSPFPTGS---AFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQ 490 PSQ+L+ + S +FG+S++GA DID NGYPDLIVGA+G ++ +YRA+PV+ + Sbjct: 381 PSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAG 440 Query: 491 LLVQDS-LNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNI-PQKLSLNAELQLDRQKPRQ 548 L V S LN K+C LP T VSCFN++ C+ A G + P+KL+ EL LD+ K + Sbjct: 441 LEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKG 500 Query: 549 G-RRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPT 607 RR L L S+ + N+ + C +A+LRDE++FRDKL+PI + + L Sbjct: 501 AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYR 560 Query: 608 EA----GMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLE 663 A G+ P + ++ Q I+LDCGED+VC P+L+++ + +G DN L Sbjct: 561 TAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLT 620 Query: 664 LQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNP 723 L + A N+GEGAYEAEL V +P A ++ + N E RL C K EN+TR V+C+LGNP Sbjct: 621 LIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNP 680 Query: 724 MKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRG 783 MK Q+ + SV E SV F LQI+S N + S +V V + A VE+RG Sbjct: 681 MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRG 740 Query: 784 NSFPASLVVAAEEGEREQN--SLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPS 841 S P + + E ++N + + GP V+H YEL NNGP + + L + P + + Sbjct: 741 VSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNN 800 Query: 842 DLLYILDIQPQGGLQCFPQPPVNPLKVD-WGLPIPSPSPIHPAHHKRD----RRQIFLPE 896 LLYIL G + C +NPL++ L + +RD +R + L E Sbjct: 801 TLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSE 860 Query: 897 PEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLD--QFV 954 D + C A C + C + + RG+ A++ V + LW + + + Sbjct: 861 -------GDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYS 913 Query: 955 LQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALE--ERAIPIWWVLVGVLGGLLLLT 1012 L+S A FNV PY P+ V T + ++ +P+W +++ VL GLLLL Sbjct: 914 LKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLA 973 Query: 1013 ILVLAMWKVGFFKRNRPPLEEDDEE 1037 +LV M+++GFFKR RPP EE + E Sbjct: 974 VLVFVMYRMGFFKRVRPPQEEQERE 998 >gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] Length = 1137 Score = 287 bits (734), Expect = 4e-77 Identities = 318/1106 (28%), Positives = 495/1106 (44%), Gaps = 169/1106 (15%) Query: 29 AWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVA--IVVGAPRTL---GPSQEETGG 83 A A NLD + G GS FGFS+ H+ R ++VGAP+ L G TGG Sbjct: 31 AVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGG 90 Query: 84 VFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSD--VIVACAPW 141 +F CP E C + D G+ + K Q LG SV S IV CA Sbjct: 91 LFACPLSLEETDCYRVDIDQ-------GADMQKESKENQWLGVSVRSQGPGGKIVTCA-- 141 Query: 142 QHWNVLEKTEEAEKTP--VGSCFLAQPESGRR-----AEYSPCRGNTLSRIYVENDFSWD 194 + ++ ++ +T +G CF+ + R E+ C G R F + Sbjct: 142 HRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEG----RPQGHEQFGFC 197 Query: 195 KRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSF 254 ++ A FS + L+ GAPG Y + GLL V +I SS ++ + Sbjct: 198 QQGTAAAFSP---DSHYLLFGAPGTYNWKGLLF---VTNIDSSDPDQLVYKTLDPADRLP 251 Query: 255 DSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL--DSYYQRLHR-- 310 + + Y G+S+ G+ +V GAP + GAV IL DS + + Sbjct: 252 GPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHK-GAVVILRKDSASRLVPEVM 310 Query: 311 LRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHA 370 L GE++ S FG+S+AV D+N DG DL+VGAP + E + + G VY++L +G H Sbjct: 311 LSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELG----GAVYVYLN-QGGHW 365 Query: 371 LGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGL 430 G L L G+ FG ++A LGDL++DG+ DIAV AP+ G G+V ++ G S G+ Sbjct: 366 AGISPLRLCGSP-DSMFGISLAVLGDLNQDGFPDIAVGAPFDGD---GKVFIYHGSSLGV 421 Query: 431 RSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQ 490 ++PSQVL+ +FG+SL G++D+D N YPDL+VG+ A+ ++RA+P++ S + Sbjct: 422 VAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPILHVSHE 480 Query: 491 LLVQDSLNPAVKSCVLPQTKTPVS---CFNIQMCVG--ATGHNIPQKLSLNAELQLDRQK 545 + + A +S L Q C ++++C A + ++L+ L D + Sbjct: 481 VSI------APRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDR 534 Query: 546 PRQGR--RVLLLG-------SQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPI 596 +G+ RV L Q +GT L +H +C M L++ + +DKL I Sbjct: 535 RLRGQVPRVTFLSRNLEEPKHQASGTVW---LKHQHDRVCGDAMFQLQE--NVKDKLRAI 589 Query: 597 VLSLNVSL-PPTEAGMAP-------AVVLHGDTHVQEQTRIVL---DCGEDDVCVPQLQL 645 V++L+ SL P AP A +L+ ++ I CGED +C LQL Sbjct: 590 VVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQL 649 Query: 646 TA--------------------------SVTGSPLLVGADNVLELQMDAAN---EGEGAY 676 +++G P++ V L D A +G+ A+ Sbjct: 650 VRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAH 709 Query: 677 EAELAVHLPQGAHY--MRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAM 734 EA+L V LP HY +RAL + E+ +C EN + V CELGNPMK+ AQ+ + Sbjct: 710 EAQLLVMLPDSLHYSGVRAL---DPAEKPLC-LSNENASHVE-CELGNPMKRGAQVTFYL 764 Query: 735 LVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVEL----RGNSFPASL 790 ++S + + +L + + + Q L V RA +EL G + P L Sbjct: 765 ILSTSGISIETTELEVELLLATISEQE------LHPVSARARVFIELPLSIAGMAIPQQL 818 Query: 791 VVA-AEEGEREQNSLDSWGPKVEHTYELHNNGPG--TVNGLHLSIHLPGQ-SQPSDLLYI 846 + GER S G KV++ + N G T+ L+I P + + LLY Sbjct: 819 FFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYP 878 Query: 847 LDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFL--PEPEQPSRLQ 904 + ++ +GG Q P GL P P+ +H RDRR+ L PE ++P Q Sbjct: 879 MQVELEGG-----QGPGQK-----GLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQ 928 Query: 905 DP---------------VLVSC--DSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQ 947 +P + + C +A C V C L R A++ V LW + + Sbjct: 929 EPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRA--AVLHVWGRLWNSTFLE 986 Query: 948 RPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLL---RALEERAIPIWWVLVGV 1004 L+ N+ ++ ++ L L + + A+ +P W +L+ V Sbjct: 987 EYSAVKSLEVIVRANI-TVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAV 1045 Query: 1005 LGGLLLLTILVLAMWKVGFFKRNRPP 1030 L GLL+L +LVL +WK+GFFKR + P Sbjct: 1046 LAGLLVLALLVLLLWKMGFFKRAKHP 1071 >gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] Length = 1141 Score = 282 bits (721), Expect = 1e-75 Identities = 317/1111 (28%), Positives = 492/1111 (44%), Gaps = 175/1111 (15%) Query: 29 AWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVA--IVVGAPRTL---GPSQEETGG 83 A A NLD + G GS FGFS+ H+ R ++VGAP+ L G TGG Sbjct: 31 AVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGG 90 Query: 84 VFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSD--VIVACAPW 141 +F CP E C + D G+ + K Q LG SV S IV CA Sbjct: 91 LFACPLSLEETDCYRVDIDQ-------GADMQKESKENQWLGVSVRSQGPGGKIVTCA-- 141 Query: 142 QHWNVLEKTEEAEKTP--VGSCFLAQPESGRR-----AEYSPCRGNTLSRIYVENDFSWD 194 + ++ ++ +T +G CF+ + R E+ C G R F + Sbjct: 142 HRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEG----RPQGHEQFGFC 197 Query: 195 KRYCEAGFSSVVTQAGELVLGAPGGYYFLG-----LLAQAPVADIFSSYRPGILLWHVSS 249 ++ A FS + L+ GAPG Y + G L AQ P + Sbjct: 198 QQGTAAAFSP---DSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGP----YEAGG 250 Query: 250 QSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL--DSYYQR 307 + P + Y+G+S+ G+ +V GAP + GAV IL DS + Sbjct: 251 EKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHK-GAVVILRKDSASRL 309 Query: 308 LHR--LRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQP 365 + L GE++ S FG+S+AV D+N DG DL+VGAP + E + + G VY++L Sbjct: 310 VPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELG----GAVYVYLN- 364 Query: 366 RGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLG 425 +G H G L L G+ FG ++A LGDL++DG+ DIAV AP+ G G+V ++ G Sbjct: 365 QGGHWAGISPLRLCGSP-DSMFGISLAVLGDLNQDGFPDIAVGAPFDGD---GKVFIYHG 420 Query: 426 QSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVV 485 S G+ ++PSQVL+ +FG+SL G++D+D N YPDL+VG+ A+ ++RA+P++ Sbjct: 421 SSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPIL 479 Query: 486 KASVQLLVQDSLNPAVKSCVLPQTKTPVS---CFNIQMCVG--ATGHNIPQKLSLNAELQ 540 S ++ + A +S L Q C ++++C A + ++L+ L Sbjct: 480 HVSHEVSI------APRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLD 533 Query: 541 LDRQKPRQGR--RVLLLG-------SQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRD 591 D + +G+ RV L Q +GT L +H +C M L++ + +D Sbjct: 534 ADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVW---LKHQHDRVCGDAMFQLQE--NVKD 588 Query: 592 KLSPIVLSLNVSL-PPTEAGMAP-------AVVLHGDTHVQEQTRIVL---DCGEDDVCV 640 KL IV++L+ SL P AP A +L+ ++ I CGED +C Sbjct: 589 KLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQ 648 Query: 641 PQLQLTA--------------------------SVTGSPLLVGADNVLELQMDAAN---E 671 LQL +++G P++ V L D A + Sbjct: 649 SNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQAD 708 Query: 672 GEGAYEAELAVHLPQGAHY--MRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQ 729 G+ A+EA+L V LP HY +RAL + E+ +C EN + V CELGNPMK+ AQ Sbjct: 709 GDDAHEAQLLVMLPDSLHYSGVRAL---DPAEKPLC-LSNENASHVE-CELGNPMKRGAQ 763 Query: 730 IGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVEL----RGNS 785 + +++S + + +L + + + Q L V RA +EL G + Sbjct: 764 VTFYLILSTSGISIETTELEVELLLATISEQE------LHPVSARARVFIELPLSIAGMA 817 Query: 786 FPASLVVA-AEEGEREQNSLDSWGPKVEHTYELHNNGPG--TVNGLHLSIHLPGQ-SQPS 841 P L + GER S G KV++ + N G T+ L+I P + + Sbjct: 818 IPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGK 877 Query: 842 DLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFL--PEPEQ 899 LLY + ++ +GG Q P GL P P+ +H RDRR+ L PE ++ Sbjct: 878 WLLYPMQVELEGG-----QGPGQK-----GLCSPRPNILHLDVDSRDRRRRELEPPEQQE 927 Query: 900 PSRLQDP---------------VLVSC--DSAPCTVVQCDLQEMARGQRAMVTVLAFLWL 942 P Q+P + + C +A C V C L R A++ V LW Sbjct: 928 PGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRA--AVLHVWGRLWN 985 Query: 943 PSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLL---RALEERAIPIWW 999 + + L+ N+ ++ ++ L L + + A+ +P W Sbjct: 986 STFLEEYSAVKSLEVIVRANI-TVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWV 1044 Query: 1000 VLVGVLGGLLLLTILVLAMWKVGFFKRNRPP 1030 +L+ VL GLL+L +LVL +WK+GFFKR + P Sbjct: 1045 ILLAVLAGLLVLALLVLLLWKMGFFKRAKHP 1075 >gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] Length = 1051 Score = 269 bits (687), Expect = 1e-71 Identities = 303/1074 (28%), Positives = 466/1074 (43%), Gaps = 158/1074 (14%) Query: 31 ALNLDPVQLTFY-AGPNGSQFGFSLDFHKDSHG--RVAIVVGAPRTLGPSQ---EETGGV 84 A NLD L AG GS FG+S+ H+ + R ++ GAPR L TG V Sbjct: 32 AFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRYLLLAGAPRELAVPDGYTNRTGAV 91 Query: 85 FLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDV--IVACAPWQ 142 +LCP A C + ++++ G ++ LG +V S ++ CA + Sbjct: 92 YLCPLTAHKDDCERMNITVKNDP---GHHIIEDM----WLGVTVASQGPAGRVLVCAH-R 143 Query: 143 HWNVLEKTEEAEKTPVGSCF-------LAQPESGRRAEYSPCRGNTLSRIYVENDFSWDK 195 + VL E ++ VG C+ L + + C NT Y+E Sbjct: 144 YTQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTYHNEMCNSNT---DYLETGM---- 196 Query: 196 RYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFD 255 C+ G S TQ + GAPG Y + G +SY W +S S Sbjct: 197 --CQLGTSGGFTQ-NTVYFGAPGAYNWKG-----------NSYMIQRKEWDLSEYSYKDP 242 Query: 256 SSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSY----YQRLHRL 311 Y GY++ VG F V GAP +GAV +L +R L Sbjct: 243 EDQGNL---YIGYTMQVGSFILHPKNITIVTGAPRHRH-MGAVFLLSQEAGGDLRRRQVL 298 Query: 312 RGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHAL 371 G Q+ +YFG ++A+ D+N DG DLLVGAP Y E RK G +Y+F+ G Sbjct: 299 EGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFE----RKEEVGGAIYVFMNQAGTSFP 354 Query: 372 GAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLR 431 PSLLL G FG ++A +GD+++DG+ DIAV AP+ G G+V ++ S+GL Sbjct: 355 AHPSLLLHGPS-GSAFGLSVASIGDINQDGFQDIAVGAPF---EGLGKVYIYHSSSKGLL 410 Query: 432 SRPSQVLDSP---FPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKAS 488 +P QV+ P + FG+SL G +D+D+N YPDL+VG+ ++ + + RA+PV+ Sbjct: 411 RQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSL-SDHIVLLRARPVINIV 469 Query: 489 VQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCV----GATGHNIPQKLSLNAELQLDRQ 544 + LV PAV P T SC +++C A N + ++L L+ DR Sbjct: 470 HKTLVP---RPAVLD---PALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRD 523 Query: 545 KPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSL 604 R+ R+ GS+ A + C L D + RDKL PI++S+N SL Sbjct: 524 --RRPPRLRFAGSESA---VFHGFFSMPEMRCQKLELLLMD--NLRDKLRPIIISMNYSL 576 Query: 605 P---PTEAGMA-----------PAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVT 650 P P + A L T VQ Q +CG D+ C LQ+ A+ Sbjct: 577 PLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQK----ECGPDNKCESNLQMRAAFV 632 Query: 651 G------SPLLVGAD-NVLELQMDAAN------EGEGAYEAELAVHLPQGAHYMRALSNV 697 S L D L L ++ N GE A+EA L + +P LS+V Sbjct: 633 SEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPAL----LLSSV 688 Query: 698 EGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSK 757 + NET + CELGNP K+N ++ + + V + + QLQ+ + Sbjct: 689 RP-----PGACQANET--IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTS 741 Query: 758 NSQN---PNSKIVLLDVPVRAE-AQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEH 813 + Q+ P +L+D ++ + V R SF V+ GE +++ G +++ Sbjct: 742 SHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVM----GESGMKTVEDVGSPLKY 797 Query: 814 TYELHNNGPGTV--NGLHLSIHLPGQ-SQPSDLLYILDIQPQGGLQCFPQPP---VNPLK 867 +++ G G V L L + P + S LLY +I G +PP +NPL Sbjct: 798 EFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLN 857 Query: 868 VDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQP--------SRLQDPVLVSCDS--APCT 917 + L P P P +R RRQ+ + P + + +++C + A C Sbjct: 858 LT--LSDPGDRPSSP---QRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCV 912 Query: 918 VVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPR 977 ++C + + VTV A +W + + D ++ + W + L ++P +++ Sbjct: 913 WLECPIPDAP--VVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATL-FLRTSIPTINMEN 969 Query: 978 GEAQVWTQLLRALEER---AIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNR 1028 + L E I +W VLV V GLLLL +++L +WK GFFKR R Sbjct: 970 KTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRAR 1023 >gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] Length = 1066 Score = 267 bits (682), Expect = 4e-71 Identities = 302/1074 (28%), Positives = 465/1074 (43%), Gaps = 158/1074 (14%) Query: 31 ALNLDPVQLTFY-AGPNGSQFGFSLDFHKDSHG--RVAIVVGAPRTLGPSQ---EETGGV 84 A NLD L AG GS FG+S+ H+ + R ++ GAPR L TG V Sbjct: 32 AFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRYLLLAGAPRELAVPDGYTNRTGAV 91 Query: 85 FLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDV--IVACAPWQ 142 +LCP A C + ++++ G ++ LG +V S ++ CA + Sbjct: 92 YLCPLTAHKDDCERMNITVKNDP---GHHIIEDM----WLGVTVASQGPAGRVLVCAH-R 143 Query: 143 HWNVLEKTEEAEKTPVGSCF-------LAQPESGRRAEYSPCRGNTLSRIYVENDFSWDK 195 + VL E ++ VG C+ L + + C NT Y+E Sbjct: 144 YTQVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTYHNEMCNSNT---DYLETGM---- 196 Query: 196 RYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFD 255 C+ G S TQ + GAPG Y + G +SY W +S S Sbjct: 197 --CQLGTSGGFTQ-NTVYFGAPGAYNWKG-----------NSYMIQRKEWDLSEYSYKDP 242 Query: 256 SSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSY----YQRLHRL 311 Y GY++ VG F V GAP +GAV +L +R L Sbjct: 243 EDQGNL---YIGYTMQVGSFILHPKNITIVTGAPRHRH-MGAVFLLSQEAGGDLRRRQVL 298 Query: 312 RGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHAL 371 G Q+ +YFG ++A+ D+N DG DLLVGAP Y E RK G +Y+F+ G Sbjct: 299 EGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFE----RKEEVGGAIYVFMNQAGTSFP 354 Query: 372 GAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLR 431 PSLLL G FG ++A +GD+++DG+ DIAV AP+ G G+V ++ S+GL Sbjct: 355 AHPSLLLHGPS-GSAFGLSVASIGDINQDGFQDIAVGAPF---EGLGKVYIYHSSSKGLL 410 Query: 432 SRPSQVLDSP---FPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKAS 488 +P QV+ P + FG+SL G +D+D+N YPDL+VG+ ++ + + RA+PV+ Sbjct: 411 RQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSL-SDHIVLLRARPVINIV 469 Query: 489 VQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCV----GATGHNIPQKLSLNAELQLDRQ 544 + LV PAV P T SC +++C A N + ++L L+ DR Sbjct: 470 HKTLVP---RPAVLD---PALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRD 523 Query: 545 KPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSL 604 R+ R+ GS+ A + C L D + RDKL PI++S+N SL Sbjct: 524 --RRPPRLRFAGSESA---VFHGFFSMPEMRCQKLELLLMD--NLRDKLRPIIISMNYSL 576 Query: 605 P---PTEAGMA-----------PAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVT 650 P P + A L T VQ Q +CG D+ C LQ+ A+ Sbjct: 577 PLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQK----ECGPDNKCESNLQMRAAFV 632 Query: 651 G------SPLLVGAD-NVLELQMDAAN------EGEGAYEAELAVHLPQGAHYMRALSNV 697 S L D L L ++ N GE A+EA L + +P LS+V Sbjct: 633 SEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPAL----LLSSV 688 Query: 698 EGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSK 757 + NET + CELGNP K+N ++ + + V + + QLQ+ + Sbjct: 689 RP-----PGACQANET--IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTS 741 Query: 758 NSQN---PNSKIVLLDVPVRAE-AQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEH 813 + Q+ P +L+D ++ + V R SF V+ GE +++ G +++ Sbjct: 742 SHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVM----GESGMKTVEDVGSPLKY 797 Query: 814 TYELHNNGPGTV--NGLHLSIHLPGQ-SQPSDLLYILDIQPQGGLQCFPQPP---VNPLK 867 +++ G G V L L + P + S LLY +I G +PP +NPL Sbjct: 798 EFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLN 857 Query: 868 VDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQP--------SRLQDPVLVSCDS--APCT 917 + L P P P +R RRQ+ + P + + +++C + A C Sbjct: 858 LT--LSDPGDRPSSP---QRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCV 912 Query: 918 VVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPR 977 ++C + + VTV A +W + + D ++ + W + L ++P +++ Sbjct: 913 WLECPIPDAP--VVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATL-FLRTSIPTINMEN 969 Query: 978 GEAQVWTQLLRALEER---AIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNR 1028 + L E I +W VLV V GLLLL +++L +WK FFKR R Sbjct: 970 KTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCDFFKRTR 1023 >gi|52485941 integrin, alpha 9 precursor [Homo sapiens] Length = 1035 Score = 249 bits (636), Expect = 1e-65 Identities = 269/1076 (25%), Positives = 460/1076 (42%), Gaps = 129/1076 (11%) Query: 18 LLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRT---L 74 LLL A PA A NLDP + + GP S FG+++ H + R ++VGAP+ Sbjct: 16 LLLALVVAGIPAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRW-VLVGAPKADSKY 74 Query: 75 GPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVG-SQTLQTFKARQGLGASVVSWSD 133 PS + G VF C + + L R + R +T + + + +G S+ Sbjct: 75 SPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMGVSLARQPK 134 Query: 134 V---IVACAPWQHW-NVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVEN 189 ++ACA W N+ + + P G C++ +G TL Y E Sbjct: 135 ADGRVLACA--HRWKNIYYEADHI--LPHGFCYIIPSNL-------QAKGRTLIPCYEEY 183 Query: 190 DFSWDKRY--CEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVAD-IFSSYRPGILLWH 246 + + + C+AG + T+ +V+GAPG +Y+ G + + D + +++ Sbjct: 184 KKKYGEEHGSCQAGIAGFFTEE-LVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEVIM-- 240 Query: 247 VSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQ 306 N Y Y GY+V G F +T + V GAP +G V I + + Sbjct: 241 -----------NRRYT--YLGYAVTAGHFSHP-STIDVVGGAPQ-DKGIGKVYIFRADRR 285 Query: 307 -----RLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYL 361 ++ + G++M SYFG S+ D+NGDG DLLVGAP++ E R + G+V + Sbjct: 286 SGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDE------GQVTV 339 Query: 362 FLQPRGPHALGAPSLLLTGTQLYG-RFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQV 420 ++ RG AL L LTG Y FG +IA L DLD DG+ D+A+ AP G V Sbjct: 340 YIN-RGNGAL-EEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFA-GAV 396 Query: 421 LVFLGQSEGLRSRPSQVLDSPF--PTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAV 478 ++ G + G+ + S L P FG S+ G +D+D NGYPD+ VGA+ ++ V + Sbjct: 397 YIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVL 456 Query: 479 YRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAE 538 RA+PV+ V + + S+N C + PV+C N+ C G ++P ++ LN Sbjct: 457 LRARPVITVDVSIFLPGSINITAPQC--HDGQQPVNCLNVTTCFSFHGKHVPGEIGLNYV 514 Query: 539 LQLDRQKPRQGRR----VLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLS 594 L D K +G+ +LLG T L L C +A ++ +D +S Sbjct: 515 LMADVAKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEE-TCRHYVAHVKRRV--QDVIS 571 Query: 595 PIVLSLNVSLPPTEAG--------MAPAVVLHGDTHVQEQTRIVLD--CGEDDVCVPQLQ 644 PIV SL G + P + + ++ + V + C +D C LQ Sbjct: 572 PIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSED-CAADLQ 630 Query: 645 LTASVTGSP-------LLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNV 697 L + S L +GA + L + +N G+ AY+A ++ ++ + ++ Sbjct: 631 LQGKLLLSSMDEKTLYLALGAVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQKE 690 Query: 698 EGFERLICNQKKENETRVVLCELGNP-MKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRS 756 E + C E+ + C +G P M+ ++ +++ +L E +SF + +S Sbjct: 691 E--MGISCELL---ESDFLKCSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQS 745 Query: 757 KNSQNPNS---KIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGER---EQNSLDSWGPK 810 N++ S ++L VP+ E + G P S V + + L+ Sbjct: 746 GNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQP 805 Query: 811 VEHTYELHNNGPGTVNGLHLSIHLPGQ--SQPSDLLYILDI---QPQG--GLQCFPQPPV 863 + T +++N GP T+ G +SI P + S +++ ++ ++ Q +G Q P P + Sbjct: 806 INITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCI 865 Query: 864 NPLKVDWGLPIPSPSPIHP--AHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQC 921 +P + H A + R++ + E+P C C Sbjct: 866 --------IPQEQENIFHTIFAFFTKSGRKVL--DCEKP------------GISCLTAHC 903 Query: 922 DLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQ 981 + +A+ + + + L L + S A V V E Sbjct: 904 NFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGNPEEVT 963 Query: 982 VWTQLLRALEERAIPIWWVL-VGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDE 1036 V + L LE R + W++ + +L G+L+ +L + +WK+GFF+R + E ++ Sbjct: 964 VVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEAEK 1019 >gi|67191027 integrin alpha 4 precursor [Homo sapiens] Length = 1032 Score = 248 bits (633), Expect = 2e-65 Identities = 285/1086 (26%), Positives = 458/1086 (42%), Gaps = 152/1086 (13%) Query: 15 EWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVA-IVVGAPRT 73 E V+LLL P N+D Y GP+ + FG+S+ H SHG ++VGAP Sbjct: 18 ETVMLLLC-LGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLH--SHGANRWLLVGAPTA 74 Query: 74 ---LGPSQEETGGVFLCPWRAEGGQ-CPSLLFDLRDETRNVGSQTLQTFKARQGLGASVV 129 S G ++ C GQ C L L +T + Q LG ++ Sbjct: 75 NWLANASVINPGAIYRCRIGKNPGQTCEQL--QLGSPNGEPCGKTCLEERDNQWLGVTLS 132 Query: 130 SW---SDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYS----PCRGNTL 182 + IV C W + + K P G C+ P+ R E S PC + + Sbjct: 133 RQPGENGSIVTCG--HRWKNIFYIKNENKLPTGGCYGVPPDL--RTELSKRIAPCYQDYV 188 Query: 183 SRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGI 242 + + EN S C+AG SS T+ +V+GAPG Y+ G L V +I ++ Sbjct: 189 KK-FGENFAS-----CQAGISSFYTK-DLIVMGAPGSSYWTGSLF---VYNITTNKYKAF 238 Query: 243 LLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL- 301 L D N F Y GYSV G F +TTE V GAP +G I Sbjct: 239 L-----------DKQNQVKFGSYLGYSVGAGHFRSQ-HTTEVVGGAPQHE-QIGKAYIFS 285 Query: 302 --DSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRV 359 + LH ++G+++ SYFG SV D+N DG DLLVGAP+ R E GRV Sbjct: 286 IDEKELNILHEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIR------EEGRV 339 Query: 360 YLFLQPRGPHALGAPSLLLTGTQLY-GRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRG 418 ++++ + A L G+ Y RFG +I LGD+D DG+ D+A+ AP +G Sbjct: 340 FVYINSGSGAVMNAMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDL-QG 398 Query: 419 QVLVFLGQSEGLRSRPSQVLD--SPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQV 476 + ++ G+++G+ S SQ ++ + S FG S+ G +D D+NGY D+ VGA+ ++ Sbjct: 399 AIYIYNGRADGISSTFSQRIEGLQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSA 458 Query: 477 AVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSL- 535 + R +PVV L +S+N CV + P C ++ +C G +P + L Sbjct: 459 VLLRTRPVVIVDASLSHPESVNRTKFDCV--ENGWPSVCIDLTLCFSYKGKEVPGYIVLF 516 Query: 536 -NAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLS 594 N L ++R+ R T ++ + + + C T AF+R D RD L+ Sbjct: 517 YNMSLDVNRKAESPPRFYFSSNGTSDVITGSIQVSSREAN-CRTHQAFMR--KDVRDILT 573 Query: 595 PIVLSLNVSLPP-------TE--AGMAPAVVLHGDTHVQEQT-RIVLDCGEDDVCVPQLQ 644 PI + L P TE + P + + + ++T C ++ C LQ Sbjct: 574 PIQIEAAYHLGPHVISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN-CSADLQ 632 Query: 645 LTASV-------TGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNV 697 ++A + + L VG+ L L + N G+ AYE L V LP G ++++ L Sbjct: 633 VSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIKILELE 692 Query: 698 EGFERLICNQKKENETRVVLCELGNPMKKN-AQIGIAMLVSVGNLEEAGESVSFQLQIRS 756 E +++ C + + C +G + ++I I+ L+ V +L A E +S + Sbjct: 693 E--KQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATC 750 Query: 757 KNSQ---NPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAA-EEGEREQNSLDSWGPKVE 812 +N + N V + +P++ E ++ + G P S V + +E E E ++ K+ Sbjct: 751 ENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFVNPTSFVYGSNDENEPETCMVE----KMN 806 Query: 813 HTYELHNNGPGTVNGLHLSIHLPGQSQP--SDLLYILDIQPQGGLQCFPQPPVNPLKVDW 870 T+ + N G + + I +P P L ILD+Q G +C Sbjct: 807 LTFHVINTGNSMAPNVSVEIMVPNSFSPQTDKLFNILDVQTTTG-EC------------- 852 Query: 871 GLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQ------------DPVLVSCDSAP--C 916 H + +R L +Q S +Q D L+ C A C Sbjct: 853 -------------HFENYQRVCAL--EQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHC 897 Query: 917 TVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAW---FNVSSLPYAVPPL 973 C+ +M G+ A V + L RP + ++ A + P P + Sbjct: 898 LNFLCNFGKMESGKEASVHI-------QLEGRPSILEMDETSALKFEIRATGFPEPNPRV 950 Query: 974 SLPRGEAQVWTQLLRALEERAIPIWWVLV----GVLGGLLLLTILVLAMWKVGFFKRNRP 1029 + V LL L + ++ +V +L GL++L ++ MWK GFFKR Sbjct: 951 IELNKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYK 1010 Query: 1030 PLEEDD 1035 + +++ Sbjct: 1011 SILQEE 1016 >gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] Length = 1044 Score = 246 bits (628), Expect = 8e-65 Identities = 275/973 (28%), Positives = 434/973 (44%), Gaps = 157/973 (16%) Query: 158 VGSCFLAQPESGRR-----AEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGEL 212 +G CF+ + R E+ C G R F + ++ A FS + L Sbjct: 63 IGRCFVLSQDLAIRDELDGGEWKFCEG----RPQGHEQFGFCQQGTAAAFSP---DSHYL 115 Query: 213 VLGAPGGYYFLG-----LLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWG 267 + GAPG Y + G L AQ P + + P + Y+G Sbjct: 116 LFGAPGTYNWKGTARVELCAQGSADLAHLDDGP----YEAGGEKEQDPRLIPVPANSYFG 171 Query: 268 YSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL--DSYYQRLHR--LRGEQMASYFGHS 323 +S+ G+ +V GAP + GAV IL DS + + L GE++ S FG+S Sbjct: 172 FSIDSGKGLVRAEELSFVAGAPRANHK-GAVVILRKDSASRLVPEVMLSGERLTSGFGYS 230 Query: 324 VAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQL 383 +AV D+N DG DL+VGAP + E + + G VY++L +G H G L L G+ Sbjct: 231 LAVADLNSDGWPDLIVGAPYFFERQEELG----GAVYVYLN-QGGHWAGISPLRLCGSP- 284 Query: 384 YGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFP 443 FG ++A LGDL++DG+ DIAV AP+ G G+V ++ G S G+ ++PSQVL+ Sbjct: 285 DSMFGISLAVLGDLNQDGFPDIAVGAPFDGD---GKVFIYHGSSLGVVAKPSQVLEGEAV 341 Query: 444 TGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKS 503 +FG+SL G++D+D N YPDL+VG+ A+ ++RA+P++ S ++ + A +S Sbjct: 342 GIKSFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPILHVSHEVSI------APRS 394 Query: 504 CVLPQTKTPVS---CFNIQMCVG--ATGHNIPQKLSLNAELQLDRQKPRQGR--RVLLLG 556 L Q C ++++C A + ++L+ L D + +G+ RV L Sbjct: 395 IDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLS 454 Query: 557 -------SQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSL-PPTE 608 Q +GT L +H +C M L++ + +DKL IV++L+ SL P Sbjct: 455 RNLEEPKHQASGTVW---LKHQHDRVCGDAMFQLQE--NVKDKLRAIVVTLSYSLQTPRL 509 Query: 609 AGMAP-------AVVLHGDTHVQEQTRIVL---DCGEDDVCVPQLQLTA----------- 647 AP A +L+ ++ I CGED +C LQL Sbjct: 510 RRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTE 569 Query: 648 ---------------SVTGSPLLVGADNVLELQMDAAN---EGEGAYEAELAVHLPQGAH 689 +++G P++ V L D A +G+ A+EA+L V LP H Sbjct: 570 FQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLH 629 Query: 690 Y--MRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGES 747 Y +RAL + E+ +C EN + V CELGNPMK+ AQ+ +++S + Sbjct: 630 YSGVRAL---DPAEKPLC-LSNENASHVE-CELGNPMKRGAQVTFYLILSTSGISIETTE 684 Query: 748 VSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVEL----RGNSFPASLVVA-AEEGEREQN 802 + +L + + + Q L V RA +EL G + P L + GER Sbjct: 685 LEVELLLATISEQE------LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQ 738 Query: 803 SLDSWGPKVEHTYELHNNGPG--TVNGLHLSIHLPGQ-SQPSDLLYILDIQPQGGLQCFP 859 S G KV++ + N G T+ L+I P + + LLY + ++ +GG Sbjct: 739 SERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGG----- 793 Query: 860 QPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFL--PEPEQPSRLQDP----------- 906 Q P GL P P+ +H RDRR+ L PE ++P Q+P Sbjct: 794 QGPGQK-----GLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAE 848 Query: 907 ----VLVSC--DSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAW 960 + + C +A C V C L R A++ V LW + + L+ Sbjct: 849 KKKNITLDCARGTANCVVFSCPLYSFDRA--AVLHVWGRLWNSTFLEEYSAVKSLEVIVR 906 Query: 961 FNVSSLPYAVPPLSLPRGEAQVWTQLL---RALEERAIPIWWVLVGVLGGLLLLTILVLA 1017 N+ ++ ++ L L + + A+ +P W +L+ VL GLL+L +LVL Sbjct: 907 ANI-TVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLL 965 Query: 1018 MWKVGFFKRNRPP 1030 +WK+GFFKR + P Sbjct: 966 LWKMGFFKRAKHP 978 >gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo sapiens] Length = 1073 Score = 236 bits (602), Expect = 8e-62 Identities = 271/1072 (25%), Positives = 469/1072 (43%), Gaps = 150/1072 (13%) Query: 44 GPNGSQFGFSLDFH--KDSHGRVAIVVGAPRTLG-PSQE--ETGGVFLCPWRAEGGQCPS 98 G GS FGFSL H + ++VGAPR P Q TGG++ C A G C Sbjct: 38 GDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGLYSCDITARG-PCTR 96 Query: 99 LLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSD--VIVACAPWQHWNVLEKTEEAEKT 156 + FD N T ++ K Q +G +V S +V CA T++ + Sbjct: 97 IEFD------NDADPTSES-KEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRD 149 Query: 157 PVGSCFLAQP-----ESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGE 211 G C++ + ++S C G R+ F C+ G ++ T+ Sbjct: 150 IFGRCYVLSQNLRIEDDMDGGDWSFCDG----RLRGHEKFG----SCQQGVAATFTKDFH 201 Query: 212 -LVLGAPGGYYFLGLLAQAPVADIF---SSYRPGILLWHVSSQSLSFDSSNPEYFDGYWG 267 +V GAPG Y + G++ + F + + G + V ++ +S P + Y G Sbjct: 202 YIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGP--YEVGGETEHDESLVPVPANSYLG 259 Query: 268 YSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLR-----GEQMASYFGH 322 +S+ G+ + +V GAP + + GAV +L + H L GE +AS FG+ Sbjct: 260 FSLDSGKGIVSKDEITFVSGAPRANHS-GAVVLLKRDMKSAHLLPEHIFDGEGLASSFGY 318 Query: 323 SVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQ 382 VAV D+N DG D+++GAP Y DR G VY+++ +G P + L GT+ Sbjct: 319 DVAVVDLNKDGWQDIVIGAPQYF----DRDGEVGGAVYVYMNQQGRWNNVKP-IRLNGTK 373 Query: 383 LYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPF 442 FG A+ +GD+++DGY DIAV APY G+V ++ G + G+ ++P+QVL Sbjct: 374 -DSMFGIAVKNIGDINQDGYPDIAVGAPY---DDLGKVFIYHGSANGINTKPTQVLKGIS 429 Query: 443 PTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVK 502 P FG+S+ G +D+D N YPD+ VG+ ++ V ++R++PV+ + V + + Sbjct: 430 PY---FGYSIAGNMDLDRNSYPDVAVGSL-SDSVTIFRSRPVINIQKTITVTPNRIDLRQ 485 Query: 503 --SCVLPQTKTPVSCFNIQMCVGAT----GHNIPQKLSLNAELQLDRQKPRQGRRVLLLG 556 +C P C ++ C T G+N + E + +R+K RV Sbjct: 486 KTACGAPSG----ICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRN 541 Query: 557 S-QQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEA----GM 611 + T L L + +C +L+D + RDKL PI ++ +V + + Sbjct: 542 QGSEPKYTQELTLKRQKQKVCMEETLWLQD--NIRDKLRPIPITASVEIQEPSSRRRVNS 599 Query: 612 APAVV----------LHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVT----------- 650 P V+ H D H ++ CG+D+VC L+L Sbjct: 600 LPEVLPILNSDEPKTAHIDVHFLKE-----GCGDDNVCNSNLKLEYKFCTREGNQDKFSY 654 Query: 651 -----GSPLLVGADNV-LELQMDAAN----------EGEGAYEAELAVHLPQGAHYMRAL 694 G P LV D + L++ N +G+ A+EA+L P Y A Sbjct: 655 LPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYS-AY 713 Query: 695 SNVEGF-ERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQ 753 + F E+ + +N ++ CELGNP K+N+ + +++S + + L+ Sbjct: 714 RELRAFPEKQLSCVANQNGSQAD-CELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLK 772 Query: 754 IRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEE-GEREQNSLDSWGPKVE 812 + + ++Q+ N + V E + + G + P+ + GE+ S D G +E Sbjct: 773 LETTSNQD-NLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIE 831 Query: 813 HTYELHNNGPGTVN--GLHLSIHLPGQ-SQPSDLLYILDIQPQG--GLQCFPQPPVNPLK 867 + + + N G N L+I P + S LLY++ ++ +G + C PQ +N L Sbjct: 832 YEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLN 891 Query: 868 VDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRL-----QDPVLVSCD-SAPCTVVQC 921 + +H+ R +R+I + + + + ++C + C ++C Sbjct: 892 LT------------ESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRC 939 Query: 922 DLQEMARGQRAMVTVLAFLWLPSLYQR--PLDQFVLQSHAWFNVSSLPYAVPPLSLPRGE 979 L+ + +A + + + LW + + L+ + A+ +V++ A + LP Sbjct: 940 PLRGL--DSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTA---AAENIRLPNAG 994 Query: 980 AQVWTQLLRA---LEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNR 1028 QV + + + +P W +LV +L G+L+L +LV +WK GFFKRN+ Sbjct: 995 TQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNK 1046 >gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo sapiens] Length = 1091 Score = 235 bits (600), Expect = 1e-61 Identities = 271/1072 (25%), Positives = 469/1072 (43%), Gaps = 150/1072 (13%) Query: 44 GPNGSQFGFSLDFH--KDSHGRVAIVVGAPRTLG-PSQE--ETGGVFLCPWRAEGGQCPS 98 G GS FGFSL H + ++VGAPR P Q TGG++ C A G C Sbjct: 38 GDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRANRTGGLYSCDITARG-PCTR 96 Query: 99 LLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSD--VIVACAPWQHWNVLEKTEEAEKT 156 + FD N T ++ K Q +G +V S +V CA T++ + Sbjct: 97 IEFD------NDADPTSES-KEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRD 149 Query: 157 PVGSCFLAQP-----ESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGE 211 G C++ + ++S C G R+ F C+ G ++ T+ Sbjct: 150 IFGRCYVLSQNLRIEDDMDGGDWSFCDG----RLRGHEKFG----SCQQGVAATFTKDFH 201 Query: 212 -LVLGAPGGYYFLGLLAQAPVADIF---SSYRPGILLWHVSSQSLSFDSSNPEYFDGYWG 267 +V GAPG Y + G++ + F + + G + V ++ +S P + Y G Sbjct: 202 YIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGP--YEVGGETEHDESLVPVPANSYLG 259 Query: 268 YSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLR-----GEQMASYFGH 322 +S+ G+ + +V GAP + + GAV +L + H L GE +AS FG+ Sbjct: 260 FSLDSGKGIVSKDEITFVSGAPRANHS-GAVVLLKRDMKSAHLLPEHIFDGEGLASSFGY 318 Query: 323 SVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQ 382 VAV D+N DG D+++GAP Y DR G VY+++ +G P + L GT+ Sbjct: 319 DVAVVDLNKDGWQDIVIGAPQYF----DRDGEVGGAVYVYMNQQGRWNNVKP-IRLNGTK 373 Query: 383 LYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPF 442 FG A+ +GD+++DGY DIAV APY G+V ++ G + G+ ++P+QVL Sbjct: 374 -DSMFGIAVKNIGDINQDGYPDIAVGAPY---DDLGKVFIYHGSANGINTKPTQVLKGIS 429 Query: 443 PTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVK 502 P FG+S+ G +D+D N YPD+ VG+ ++ V ++R++PV+ + V + + Sbjct: 430 PY---FGYSIAGNMDLDRNSYPDVAVGSL-SDSVTIFRSRPVINIQKTITVTPNRIDLRQ 485 Query: 503 --SCVLPQTKTPVSCFNIQMCVGAT----GHNIPQKLSLNAELQLDRQKPRQGRRVLLLG 556 +C P C ++ C T G+N + E + +R+K RV Sbjct: 486 KTACGAPSG----ICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRN 541 Query: 557 S-QQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEA----GM 611 + T L L + +C +L+D + RDKL PI ++ +V + + Sbjct: 542 QGSEPKYTQELTLKRQKQKVCMEETLWLQD--NIRDKLRPIPITASVEIQEPSSRRRVNS 599 Query: 612 APAVV----------LHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVT----------- 650 P V+ H D H ++ CG+D+VC L+L Sbjct: 600 LPEVLPILNSDEPKTAHIDVHFLKE-----GCGDDNVCNSNLKLEYKFCTREGNQDKFSY 654 Query: 651 -----GSPLLVGADNV-LELQMDAAN----------EGEGAYEAELAVHLPQGAHYMRAL 694 G P LV D + L++ N +G+ A+EA+L P Y A Sbjct: 655 LPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYS-AY 713 Query: 695 SNVEGF-ERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQ 753 + F E+ + +N ++ CELGNP K+N+ + +++S + + L+ Sbjct: 714 RELRAFPEKQLSCVANQNGSQAD-CELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLK 772 Query: 754 IRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEE-GEREQNSLDSWGPKVE 812 + + ++Q+ N + V E + + G + P+ + GE+ S D G +E Sbjct: 773 LETTSNQD-NLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIE 831 Query: 813 HTYELHNNGPGTVN--GLHLSIHLPGQ-SQPSDLLYILDIQPQG--GLQCFPQPPVNPLK 867 + + + N G N L+I P + S LLY++ ++ +G + C PQ +N L Sbjct: 832 YEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKGLEKVTCEPQKEINSLN 891 Query: 868 VDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRL-----QDPVLVSCD-SAPCTVVQC 921 + +H+ R +R+I + + + + ++C + C ++C Sbjct: 892 LT------------ESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRC 939 Query: 922 DLQEMARGQRAMVTVLAFLWLPSLYQR--PLDQFVLQSHAWFNVSSLPYAVPPLSLPRGE 979 L+ + +A + + + LW + + L+ + A+ +V++ A + LP Sbjct: 940 PLRGL--DSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTA---AAENIRLPNAG 994 Query: 980 AQVWTQLLRA---LEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNR 1028 QV + + + +P W +LV +L G+L+L +LV +WK GFFKR+R Sbjct: 995 TQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRSR 1046 >gi|31657142 integrin, alpha 1 precursor [Homo sapiens] Length = 1179 Score = 187 bits (476), Expect = 3e-47 Identities = 210/880 (23%), Positives = 362/880 (41%), Gaps = 106/880 (12%) Query: 192 SWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQS 251 S++ + GFS+ +Q ++LGA G Y + G + + I P ++V S Sbjct: 372 SFEMEMSQTGFSAHYSQDW-VMLGAVGAYDWNGTVVMQKASQIII---PRNTTFNVES-- 425 Query: 252 LSFDSSNPEYFDGYWGYSV-AVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL---DSYYQR 307 + E Y GY+V + GD+ Y+ G P ++ T G V I D + Sbjct: 426 ----TKKNEPLASYLGYTVNSATASSGDVL---YIAGQPRYNHT-GQVIIYRMEDGNIKI 477 Query: 308 LHRLRGEQMASYFGHSVAVTDVNGDGRHD-LLVGAPLYMESRADRKLAEVGRVYLFL--Q 364 L L GEQ+ SYFG + TD++ D D LLVGAP+YM + + E G+VY++ Q Sbjct: 478 LQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKE----EQGKVYVYALNQ 533 Query: 365 PRGPHALGAPSLLLT---------------GTQLYGRFGSAIAPLGDLDRDGYNDIAVAA 409 R + + + T RFG+AIA + DL+ DG+NDI + A Sbjct: 534 TRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGA 593 Query: 410 PYGGPSGRGQVLVFLGQSEGLRSRPSQVLDS--PFPTGSAFGFSLRGAVDIDDNGYPDLI 467 P G G V ++ G + +R +Q + S T FG S+ G +D++ +G D+ Sbjct: 594 PLEDDHG-GAVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVT 652 Query: 468 VGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGA--- 524 +G G + R VVK ++ + +N K+C + +T C N +C Sbjct: 653 IGGLGGAALFWSRDVAVVKVTMNF-EPNKVNIQKKNCHMEGKETV--CINATVCFDVKLK 709 Query: 525 TGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLR 584 + + + L + LD RQ R G+Q+ N+ + C ++ Sbjct: 710 SKEDTIYEADLQYRVTLDSL--RQISRSFFSGTQERKVQRNITVRKSE---CTKHSFYML 764 Query: 585 DEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQ 644 D+ DF+D + ++L+ +L E G L H E DCG + C+ L Sbjct: 765 DKHDFQDSVR---ITLDFNLTDPENGPVLDDSLPNSVH--EYIPFAKDCGNKEKCISDLS 819 Query: 645 LTASVTGSPLLV--GADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFER 702 L + T LL+ ++ + + N + AY VH + S +E ++ Sbjct: 820 LHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVF----SGIEAIQK 875 Query: 703 LICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNP 762 C + C++G P + ++ ++ N E+V+ L S + + P Sbjct: 876 DSCESNHN-----ITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPP 930 Query: 763 NS---KIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQ-NSLDSWGPKVEHTYELH 818 + +V + +PV+ E ++ ++ + +AA E E NS + G ++ Y + Sbjct: 931 ETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIR 990 Query: 819 NNGPGTVNGLHLSIHLPGQ-SQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSP 877 +G + L LSI P S +LY + C P +P ++ G + + Sbjct: 991 KSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTS 1050 Query: 878 SPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVL 937 + H KR ++ C++ + C+L Q V V Sbjct: 1051 TD----HLKRG------------------TILDCNTCKFATITCNLTSSDISQ---VNVS 1085 Query: 938 AFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPI 997 LW P+ + L + LS + ++ Q+ + +P+ Sbjct: 1086 LILWKPTFIKSYFSSLNLTIRGELRSENASLV---LSSSNQKRELAIQISKDGLPGRVPL 1142 Query: 998 WWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEE 1037 W +L+ GLLLL +L+LA+WK+GFFKR PL++ E+ Sbjct: 1143 WVILLSAFAGLLLLMLLILALWKIGFFKR---PLKKKMEK 1179 Score = 36.2 bits (82), Expect = 0.17 Identities = 24/96 (25%), Positives = 46/96 (47%), Gaps = 7/96 (7%) Query: 16 WVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLG 75 W+L ++ C + N+D ++GP FG+++ +++ G+ +++G+P +G Sbjct: 17 WLLTVVLRCCV----SFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGK-WVLIGSP-LVG 70 Query: 76 PSQEETGGVFLCP-WRAEGGQCPSLLFDLRDETRNV 110 + TG V+ CP R E C L + NV Sbjct: 71 QPKNRTGDVYKCPVGRGESLPCVKLDLPVNTSIPNV 106 >gi|62548866 integrin, alpha D precursor [Homo sapiens] Length = 1161 Score = 170 bits (431), Expect = 6e-42 Identities = 221/880 (25%), Positives = 366/880 (41%), Gaps = 117/880 (13%) Query: 192 SWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLW--HVSS 249 S+ + GFS+ +T G L LGA G + + G G L+ ++S Sbjct: 345 SFQHEMSQEGFSTALTMDG-LFLGAVGSFSWSG----------------GAFLYPPNMSP 387 Query: 250 QSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEI--LDSYYQR 307 ++ N + D Y GYS + + G N V+GAP + T AV + +++ Sbjct: 388 TFINMSQENVDMRDSYLGYSTELALWKGVQNL---VLGAPRYQHTGKAVIFTQVSRQWRK 444 Query: 308 LHRLRGEQMASYFGHSVAVTDVNGDGRHDL-LVGAPLYMESRADRKLAEVGRVYLFLQPR 366 + G Q+ SYFG S+ DV+ DG DL L+GAP Y E G+V + PR Sbjct: 445 KAEVTGTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYEQTRG------GQVSVCPLPR 498 Query: 367 GPHALGAPSLLLTGTQ--LYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFL 424 G +L G Q +GRFG+A+ LGD++ D D+A+ AP G RG V +F Sbjct: 499 G-RVQWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAP-GEQENRGAVYLFH 556 Query: 425 GQSE-GLRSRPSQVLDSP--FPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRA 481 G SE G+ SQ + S P FG +L G D+ +G DL VGA G QV + R+ Sbjct: 557 GASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVGARG--QVLLLRS 614 Query: 482 QPVVKASVQLLVQD-SLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQ 540 PV+K V + + AV C + + + + +C+ ++ Q + + ++ Sbjct: 615 LPVLKVGVAMRFSPVEVAKAVYRC-WEEKPSALEAGDATVCLTIQKSSLDQLGDIQSSVR 673 Query: 541 LD--RQKPRQGRRVLLLGSQQAGTTLNLDLG-GKHSPICHTTMAFLRDEADFRDKLSPIV 597 D R R + ++ T LG G H C T L D + D +SPI+ Sbjct: 674 FDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIH---CETLKLLLPDCVE--DVVSPII 728 Query: 598 LSLNVSLP----PTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTG-S 652 L LN SL P+ + P + + +CG+D +C L +T S +G Sbjct: 729 LHLNFSLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTLSFSGLQ 788 Query: 653 PLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNV----EGFERLICN-- 706 L VG+ L + + N GE +Y ++++ P G + R + RL C Sbjct: 789 TLTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETV 848 Query: 707 QKKENETRVVLCELGNPMKKNAQIGIAMLV-SVGNLEEAGESVSFQLQIRSKNSQNPNSK 765 ++ R C + +P+ G ++ V G+ + + S+N++ +SK Sbjct: 849 PTEDEGLRSSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASSENNKASSSK 908 Query: 766 IVL-LDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGT 824 L++PV+ + A E++ + EH Y ++N + Sbjct: 909 ATFQLELPVKYAVYTMISRQEESTKYFNFATSDEKKMK-------EAEHRYRVNNL---S 958 Query: 825 VNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAH 884 L +SI+ F P + W + + +PS P Sbjct: 959 QRDLAISIN------------------------FWVPVLLNGVAVWDVVMEAPSQSLPCV 994 Query: 885 HKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTV---LAFLW 941 +R Q + +++ ++ C A C +CD+ + + T+ L+F W Sbjct: 995 SERKPPQ----HSDFLTQISRSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGW 1050 Query: 942 LPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEE----RAIPI 997 + Q+ + ++ S A + Y+ LP EA + Q+ LEE AIPI Sbjct: 1051 VRETLQK---KVLVVSVAEITFDTSVYS----QLPGQEAFMRAQMEMVLEEDEVYNAIPI 1103 Query: 998 WWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEE 1037 ++ +G LLLL ++ ++K+GFFKR+ + ED E Sbjct: 1104 --IMGSSVGALLLLALITATLYKLGFFKRHYKEMLEDKPE 1141 >gi|116295258 integrin alpha 2 precursor [Homo sapiens] Length = 1181 Score = 169 bits (427), Expect = 2e-41 Identities = 213/881 (24%), Positives = 370/881 (41%), Gaps = 106/881 (12%) Query: 187 VENDFSWDKRYCEAGFSSVVTQAGE-LVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLW 245 V+ ++ + GFS+ + + L+LGA G + + G + Q G L++ Sbjct: 368 VQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKT--------SHGHLIF 419 Query: 246 HVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYY 305 + N + GY +++ GE +T +V GAP ++T G + +L S Sbjct: 420 PKQAFDQILQDRNHSSYLGYSVAAISTGE------STHFVAGAPRANYT-GQI-VLYSVN 471 Query: 306 QR-----LHRLRGEQMASYFGHSVAVTDVNGDGRHD-LLVGAPLYMESRADRKLAEVGRV 359 + + RG+Q+ SYFG + DV+ D D LLVGAP+YM +D K E GRV Sbjct: 472 ENGNITVIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYM---SDLKKEE-GRV 527 Query: 360 YLFLQPRGPHALGAPSLLLTGTQLYG-RFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRG 418 YLF G LG L + RFGSAIA L D++ DG+ND+ V +P + G Sbjct: 528 YLFTIKEG--ILGQHQFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNS-G 584 Query: 419 QVLVFLGQSEGLRSRPSQVL---DSPFPTG-SAFGFSLRGAVDIDDNGYPDLIVGAYGAN 474 V ++ G +R++ SQ + D F + FG SL G D++ + D+ +GA+G Sbjct: 585 AVYIYNGHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFG-- 642 Query: 475 QVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSC---FNIQMCVGA----TGH 527 QV VQL Q + A+++ P+ T V+ +++C A T Sbjct: 643 QV------------VQLWSQSIADVAIEASFTPEKITLVNKNAQIILKLCFSAKFRPTKQ 690 Query: 528 NIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEA 587 N + N L D R R L + + N+ + S C + ++++ + Sbjct: 691 NNQVAIVYNITLDADGFSSRVTSRGLFKENNERCLQKNMVVNQAQS--CPEHIIYIQEPS 748 Query: 588 DFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTA 647 D + L L V + G +PA+ + +T DCGED +C+ L L Sbjct: 749 DVVNSLD-----LRVDISLENPGTSPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDV 803 Query: 648 ----SVTGSPLLVGADNV-LELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFER 702 + P +V N L + N+ E AY + V + + V+G E Sbjct: 804 RQIPAAQEQPFIVSNQNKRLTFSVTLKNKRESAYNTGIVVDFSENLFFASFSLPVDGTE- 862 Query: 703 LICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQ-N 761 + C ++ V C++G P K Q + NL+ S Q S++ + N Sbjct: 863 VTCQVAASQKS--VACDVGYPALKREQQVTFTINFDFNLQNLQNQASLSFQALSESQEEN 920 Query: 762 PNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQ--NSLDSWGPKVEHTYELHN 819 +V L +P+ +A++ L S + + +G +S + GPK + ++ Sbjct: 921 KADNLVNLKIPLLYDAEIHLT-RSTNINFYEISSDGNVPSIVHSFEDVGPKFIFSLKV-T 978 Query: 820 NGPGTVNGLHLSIHLPGQSQPSD-LLYILDIQPQ--GGLQCFPQPPVNPLKVDWGLPIPS 876 G V+ + IH+P ++ + L+Y+ +Q G + C +NPLK+ S Sbjct: 979 TGSVPVSMATVIIHIPQYTKEKNPLMYLTGVQTDKAGDISC--NADINPLKIGQ----TS 1032 Query: 877 PSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTV 936 S + + R +++ +C +A C+ V C L+++ V V Sbjct: 1033 SSVSFKSENFRHTKEL-----------------NCRTASCSNVTCWLKDVHMKGEYFVNV 1075 Query: 937 LAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIP 996 +W + L + A N + V + + +++ E+ +P Sbjct: 1076 TTRIWNGTFASSTFQTVQLTAAAEINTYNPEIYV----IEDNTVTIPLMIMKPDEKAEVP 1131 Query: 997 IWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEE 1037 ++ ++ G+LLL LV +WK+GFFKR + ++ +E Sbjct: 1132 TGVIIGSIIAGILLLLALVAILWKLGFFKRKYEKMTKNPDE 1172 >gi|38569398 integrin, alpha 10 precursor [Homo sapiens] Length = 1167 Score = 156 bits (395), Expect = 8e-38 Identities = 201/769 (26%), Positives = 320/769 (41%), Gaps = 101/769 (13%) Query: 296 GAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHD-LLVGAPLYMESRADRKLA 354 GAV + S L+GEQ+ SYFG + D + DG D LLV AP+++ + Sbjct: 469 GAVRVAQS-------LQGEQIGSYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQNK---- 517 Query: 355 EVGRVYLFLQPRGPHALGAPSLL-LTGT-----QLYGRFGSAIAPLGDLDRDGYNDIAVA 408 E GRVY++L +G SLL L GT RFG A+ L DL++DG+ D+AV Sbjct: 518 ETGRVYVYL-------VGQQSLLTLQGTLQPEPPQDARFGFAMGALPDLNQDGFADVAVG 570 Query: 409 APYGGPSGRGQVLVFLGQSEGLRSRPSQ-VLDSPFPTG-SAFGFSLRGAVDIDDNGYPDL 466 AP +G + ++ G G+R P+Q + + P S FG S+ G +D+D + D+ Sbjct: 571 APL-EDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSYFGRSVDGRLDLDGDDLVDV 629 Query: 467 IVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATG 526 VGA GA + ++P+V + L V V+ + + V C +C T Sbjct: 630 AVGAQGA--AILLSSRPIVHLTPSLEVTPQAISVVQRDCRRRGQEAV-CLTAALCFQVTS 686 Query: 527 H---NIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQ--AGTTLNLDLGGKHSPICHTTMA 581 + + LD G R GS Q + L L +G + C Sbjct: 687 RTPGRWDHQFYMRFTASLDEW--TAGARAAFDGSGQRLSPRRLRLSVG---NVTCEQLHF 741 Query: 582 FLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLH--GDTHVQEQTRIVLDCGEDDVC 639 + D +D+ L P+ L++ +L T P VL+ T +Q+ DCG D+ C Sbjct: 742 HVLDTSDY---LRPVALTVTFALDNT---TKPGPVLNEGSPTSIQKLVPFSKDCGPDNEC 795 Query: 640 VPQ--LQLTASVTGS---PLLV-GADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRA 693 V LQ+ + GS P +V G + + N E AY L++ + H Sbjct: 796 VTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLENRKENAYNTSLSLIFSRNLHLASL 855 Query: 694 LSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQ 753 E ++ C + LC +G+P+ + A + + E + S+ Q+ Sbjct: 856 TPQRESPIKVECAAPSAHAR---LCSVGHPVFQTG----AKVTFLLEFEFSCSSLLSQVF 908 Query: 754 IR-SKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLD-SWGPKV 811 ++ + +S + L D + A ++ + +S +L GP+ Sbjct: 909 VKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSESTLHRYEVHPYGTLPVGPGPEF 968 Query: 812 EHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWG 871 + T + N G V+GL +S LP + + L C Q P Sbjct: 969 KTTLRVQNLGCYVVSGLIISALLPAVAHGGNYFLSLSQVITNNASCIVQNLTEP------ 1022 Query: 872 LPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQR 931 P P P+H P LQ ++ + C VV+C L ++A+G Sbjct: 1023 ---PGP-PVH------------------PEELQHTNRLNGSNTQCQVVRCHLGQLAKGTE 1060 Query: 932 AMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQ-LLRAL 990 V +L + + + S F + + +V L+ EA W++ LL + Sbjct: 1061 VSVGLLRLVHNEFFRRAKFKSLTVVS--TFELGTEEGSVLQLT----EASRWSESLLEVV 1114 Query: 991 EERAIPI-WWVLVG-VLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEE 1037 + R I I W+L+G VLGGLLLL +LV +WK+GFF + P EE EE Sbjct: 1115 QTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIPEEEKREE 1163 Score = 35.0 bits (79), Expect = 0.37 Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 7/72 (9%) Query: 17 VLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGP 76 ++ L G C+ NLD + GP ++FG+S+ H G+ ++VGAP GP Sbjct: 13 LVFLTGLCSP-----FNLDEHHPRLFPGPPEAEFGYSVLQHVGG-GQRWMLVGAPWD-GP 65 Query: 77 SQEETGGVFLCP 88 S + G V+ CP Sbjct: 66 SGDRRGDVYRCP 77 >gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] Length = 1153 Score = 149 bits (377), Expect = 1e-35 Identities = 214/891 (24%), Positives = 352/891 (39%), Gaps = 155/891 (17%) Query: 192 SWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQS 251 S++ + GFS+ +T G L L G Y + G G+ L+ +S Sbjct: 345 SFEHEMSQEGFSAAITSNGPL-LSTVGSYDWAG----------------GVFLYTSKEKS 387 Query: 252 --LSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL---DSYYQ 306 ++ + + D Y GY+ A+ + V+GAP + +G V + ++ Sbjct: 388 TFINMTRVDSDMNDAYLGYAAAIILRN---RVQSLVLGAPRYQH-IGLVAMFRQNTGMWE 443 Query: 307 RLHRLRGEQMASYFGHSVAVTDVNGDGRHDL-LVGAPLYMESRADRKLAEVGRVYLFLQP 365 ++G Q+ +YFG S+ DV+ +G DL L+GAP Y E G+V + P Sbjct: 444 SNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRG------GQVSVCPLP 497 Query: 366 RGPHALGAPSLLLTGTQ--LYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVF 423 RG A +L G Q +GRFG+A+ LGD++ D D+A+ AP G RG V +F Sbjct: 498 RGQRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLF 556 Query: 424 LGQS-EGLRSRPSQVLDSP--FPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYR 480 G S G+ SQ + P FG SL G D+ +G DL VGA G V + R Sbjct: 557 HGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLR 614 Query: 481 AQPVVKAS---------VQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQ 531 +QPV++ V V + + VK + + C ++Q Sbjct: 615 SQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRV---CLHVQKSTRDRLREGQI 671 Query: 532 KLSLNAELQLDRQKPRQG-----------RRVLLLGSQQAGTTLNLDLGGKHSPICHTTM 580 + + +L LD +P R+ +LG Q TL L L P C Sbjct: 672 QSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQL-----PNC---- 722 Query: 581 AFLRDEADFRDKLSPIVLSLNVSLPPTE----AGMAPAVVLHGDTHVQEQTRIVLDCGED 636 D +SPIVL LN SL T + P + +CG D Sbjct: 723 --------IEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGND 774 Query: 637 DVCVPQLQLTASVTGSP-LLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALS 695 ++C L +T S L+VG + + N+GE +Y ++ P Y R +S Sbjct: 775 NICQDDLSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSY-RKVS 833 Query: 696 NVEGFE-----RLICNQKKENETRVVL----CELGNPM-KKNAQIGIAMLVSVGNLEEAG 745 ++ RL C E L C + +P+ +N+++ + V + G Sbjct: 834 TLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLG 893 Query: 746 ESVSFQLQIRSKNSQNPNSKIVL-LDVPVRAEAQVELRGNSFPASLV--VAAEEGEREQN 802 + + + S+N+ +K L++PV+ + + + + A+E R Sbjct: 894 NKLLLKANVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSR--- 950 Query: 803 SLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPP 862 ++H Y++ N G +S P L++++ ++ Sbjct: 951 -------VMQHQYQVSNLGQ--------------RSLPISLVFLVPVRLN---------- 979 Query: 863 VNPLKVDWGLP-IPSPSPIHPAHHKRDRRQIFLP-EPEQPSRLQDPVLVSCDSAPCTVVQ 920 V W P + + H ++R LP + + L+ +V+C A C +Q Sbjct: 980 ---QTVIWDRPQVTFSENLSSTCHTKER----LPSHSDFLAELRKAPVVNCSIAVCQRIQ 1032 Query: 921 CDLQEMARGQRAMVTV---LAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPR 977 CD+ + T+ L+F W L V + FN S LP Sbjct: 1033 CDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHL-LIVSTAEILFNDSVFTL------LPG 1085 Query: 978 GEAQVWTQLLRALE--ERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKR 1026 A V +Q +E E P+ ++ +GGLLLL ++ A++K+GFFKR Sbjct: 1086 QGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKR 1136 >gi|34452173 integrin alpha X precursor [Homo sapiens] Length = 1163 Score = 145 bits (367), Expect = 1e-34 Identities = 218/889 (24%), Positives = 353/889 (39%), Gaps = 137/889 (15%) Query: 192 SWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLW--HVSS 249 S++ + GFS+V T G VLGA G + + G G L+ ++S Sbjct: 346 SFELEMAQEGFSAVFTPDGP-VLGAVGSFTWSG----------------GAFLYPPNMSP 388 Query: 250 QSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEI--LDSYYQR 307 ++ N + D Y GYS + + G V+GAP + T AV + ++ Sbjct: 389 TFINMSQENVDMRDSYLGYSTELALWKG---VQSLVLGAPRYQHTGKAVIFTQVSRQWRM 445 Query: 308 LHRLRGEQMASYFGHSVAVTDVNGDGRHDL-LVGAPLYMESRADRKLAEVGRVYLFLQPR 366 + G Q+ SYFG S+ DV+ DG DL L+GAP Y E G+V + PR Sbjct: 446 KAEVTGTQIGSYFGASLCSVDVDSDGSTDLVLIGAPHYYEQTRG------GQVSVCPLPR 499 Query: 367 GPHALGAPSLLLTGTQ--LYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVF- 423 G ++L G Q +GRFG+A+ LGD++ D D+ + AP G RG V +F Sbjct: 500 GWRRWWCDAVLY-GEQGHPWGRFGAALTVLGDVNGDKLTDVVIGAP-GEEENRGAVYLFH 557 Query: 424 --LGQSEGLRSRPSQVLDSPFPTG-SAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYR 480 LG S S ++ S + FG +L G D+ +G DL VGA G QV + R Sbjct: 558 GVLGPSIS-PSHSQRIAGSQLSSRLQYFGQALSGGQDLTQDGLVDLAVGARG--QVLLLR 614 Query: 481 AQPV--VKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAE 538 +PV V S+Q + + A + ++ + NI + + N+ L + Sbjct: 615 TRPVLWVGVSMQFIPAEIPRSAFECREQVVSEQTLVQSNICLYIDKRSKNLLGSRDLQSS 674 Query: 539 LQLD---------------RQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFL 583 + LD K R RV +LG + NL L P C Sbjct: 675 VTLDLALDPGRLSPRATFQETKNRSLSRVRVLGLKAHCENFNLLL-----PSC------- 722 Query: 584 RDEADFRDKLSPIVLSLNVSL--PPTEA--GMAPAVVLHGDTHVQEQTRIVLDCGEDDVC 639 D ++PI L LN +L P A + P + + +CG D +C Sbjct: 723 -----VEDSVTPITLRLNFTLVGKPLLAFRNLRPMLAADAQRYFTASLPFEKNCGADHIC 777 Query: 640 VPQLQLTASVTG-SPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVE 698 L ++ S G LLVG++ L ++ N+GE +Y + P G Y + Sbjct: 778 QDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGLSYRYVAEGQK 837 Query: 699 GFE----RLICNQKK--ENETRVVLCELGNPM-KKNAQIGIAMLVSVGNLEEAGESVSFQ 751 + L C+ T C + + + + AQI V G+ + Sbjct: 838 QGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAVLGDRLLLT 897 Query: 752 LQIRSKNSQNPNSKIVL-LDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPK 810 + S+N+ SK L++PV+ + + + +E E+E + Sbjct: 898 ANVSSENNTPRTSKTTFQLELPVKYAVYTVVSSHEQFTKYLNFSESEEKESH-------V 950 Query: 811 VEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDW 870 H Y+++N G L +SI+ + + +D++ P NP Sbjct: 951 AMHRYQVNNLGQ---RDLPVSINFWVPVELNQEAVWMDVE--------VSHPQNPSLRCS 999 Query: 871 GLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQ 930 I P+ AH ++ +PVL C A C +CD+ + + Sbjct: 1000 SEKIAPPASDFLAHIQK-----------------NPVL-DCSIAGCLRFRCDVPSFSVQE 1041 Query: 931 RAMVTV---LAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLL 987 T+ L+F W+ + Q+ + + S A + Y+ LP EA + Q Sbjct: 1042 ELDFTLKGNLSFGWVRQILQKKVS---VVSVAEITFDTSVYS----QLPGQEAFMRAQTT 1094 Query: 988 RALEERAI--PIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEED 1034 LE+ + P ++ +GGLLLL ++ ++KVGFFKR + E+ Sbjct: 1095 TVLEKYKVHNPTPLIVGSSIGGLLLLALITAVLYKVGFFKRQYKEMMEE 1143 >gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] Length = 1152 Score = 145 bits (366), Expect = 2e-34 Identities = 212/890 (23%), Positives = 351/890 (39%), Gaps = 154/890 (17%) Query: 192 SWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQS 251 S++ + GFS+ +T G L L G Y + G G+ L+ +S Sbjct: 345 SFEHEMSQEGFSAAITSNGPL-LSTVGSYDWAG----------------GVFLYTSKEKS 387 Query: 252 --LSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL---DSYYQ 306 ++ + + D Y GY+ A+ + V+GAP + +G V + ++ Sbjct: 388 TFINMTRVDSDMNDAYLGYAAAIILRN---RVQSLVLGAPRYQH-IGLVAMFRQNTGMWE 443 Query: 307 RLHRLRGEQMASYFGHSVAVTDVNGDGRHDL-LVGAPLYMESRADRKLAEVGRVYLFLQP 365 ++G Q+ +YFG S+ DV+ +G DL L+GAP Y E G+V + P Sbjct: 444 SNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRG------GQVSVCPLP 497 Query: 366 RGPHALGAPSLLLTGT-QLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFL 424 RG ++L Q +GRFG+A+ LGD++ D D+A+ AP G RG V +F Sbjct: 498 RGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFH 556 Query: 425 GQS-EGLRSRPSQVLDSP--FPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRA 481 G S G+ SQ + P FG SL G D+ +G DL VGA G V + R+ Sbjct: 557 GTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQG--HVLLLRS 614 Query: 482 QPVVKAS---------VQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQK 532 QPV++ V V + + VK + + C ++Q + Sbjct: 615 QPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRV---CLHVQKSTRDRLREGQIQ 671 Query: 533 LSLNAELQLDRQKPRQG-----------RRVLLLGSQQAGTTLNLDLGGKHSPICHTTMA 581 + +L LD +P R+ +LG Q TL L L P C Sbjct: 672 SVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQL-----PNC----- 721 Query: 582 FLRDEADFRDKLSPIVLSLNVSLPPTE----AGMAPAVVLHGDTHVQEQTRIVLDCGEDD 637 D +SPIVL LN SL T + P + +CG D+ Sbjct: 722 -------IEDPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDN 774 Query: 638 VCVPQLQLTASVTGSP-LLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSN 696 +C L +T S L+VG + + N+GE +Y ++ P Y R +S Sbjct: 775 ICQDDLSITFSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSY-RKVST 833 Query: 697 VEGFE-----RLICNQKKENETRVVL----CELGNPM-KKNAQIGIAMLVSVGNLEEAGE 746 ++ RL C E L C + +P+ +N+++ + V + G Sbjct: 834 LQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGN 893 Query: 747 SVSFQLQIRSKNSQNPNSKIVL-LDVPVRAEAQVELRGNSFPASLV--VAAEEGEREQNS 803 + + + S+N+ +K L++PV+ + + + + A+E R Sbjct: 894 KLLLKANVTSENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSR---- 949 Query: 804 LDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPV 863 ++H Y++ N G +S P L++++ ++ Sbjct: 950 ------VMQHQYQVSNLGQ--------------RSLPISLVFLVPVRLN----------- 978 Query: 864 NPLKVDWGLP-IPSPSPIHPAHHKRDRRQIFLP-EPEQPSRLQDPVLVSCDSAPCTVVQC 921 V W P + + H ++R LP + + L+ +V+C A C +QC Sbjct: 979 --QTVIWDRPQVTFSENLSSTCHTKER----LPSHSDFLAELRKAPVVNCSIAVCQRIQC 1032 Query: 922 DLQEMARGQRAMVTV---LAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRG 978 D+ + T+ L+F W L V + FN S LP Sbjct: 1033 DIPFFGIQEEFNATLKGNLSFDWYIKTSHNHL-LIVSTAEILFNDSVFTL------LPGQ 1085 Query: 979 EAQVWTQLLRALE--ERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKR 1026 A V +Q +E E P+ ++ +GGLLLL ++ A++K+GFFKR Sbjct: 1086 GAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKR 1135 >gi|52485853 integrin, alpha 11 precursor [Homo sapiens] Length = 1188 Score = 142 bits (359), Expect = 1e-33 Identities = 212/899 (23%), Positives = 353/899 (39%), Gaps = 140/899 (15%) Query: 188 ENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHV 247 +N+ S+ + GFSS V + G L LGA G Y + G + + A R L Sbjct: 357 KNETSFGLEMSQTGFSSHVVEDGVL-LGAVGAYDWNGAVLKETSAGKVIPLRESYL---- 411 Query: 248 SSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQR 307 + + N + GY SV V G + YV GAP ++ T G V + + R Sbjct: 412 --KEFPEELKNHGAYLGYTVTSV-VSSRQGRV----YVAGAPRFNHT-GKVILFTMHNNR 463 Query: 308 ---LHR-LRGEQMASYFGHSVAVTDVNGDGRHD-LLVGAPLYMESRADRKLAEVGRVYLF 362 +H+ +RG+Q+ SYFG + D++GDG D LLVGAP+Y +R G+VY++ Sbjct: 464 SLTIHQAMRGQQIGSYFGSEITSVDIDGDGVTDVLLVGAPMYFNEGRER-----GKVYVY 518 Query: 363 LQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLV 422 + +L + + RFGS+IA + DL++D YND+ V AP + G + + Sbjct: 519 ELRQNLFVYNG-TLKDSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPL-EDNHAGAIYI 576 Query: 423 FLGQSEGLRSRPSQ-VLDSPFPTG-SAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYR 480 F G + P Q + S TG FG S+ G +D++++G DL VGA G N V ++ Sbjct: 577 FHGFRGSILKTPKQRITASELATGLQYFGCSIHGQLDLNEDGLIDLAVGALG-NAVILW- 634 Query: 481 AQPVVKASVQLLVQDS-LNPAVKSCVLPQTKTPVSCFNIQMC--------------VGAT 525 ++PVV+ + L + S +N + C ++ +C +C VG Sbjct: 635 SRPVVQINASLHFEPSKINIFHRDC--KRSGRDATCLAAFLCFTPIFLAPHFQTTTVGIR 692 Query: 526 GHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRD 585 + + LD R R +LL S Q +C + D Sbjct: 693 YNATMDERRYTPRAHLDEGGDRFTNRAVLLSSGQ--------------ELCERINFHVLD 738 Query: 586 EADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQL 645 AD+ + P+ S+ SL + G P + T ++ C ED+ CVP L L Sbjct: 739 TADY---VKPVTFSVEYSLEDPDHG--PMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVL 793 Query: 646 TASVTGSPLLVGADNVLE----------------------------LQMDAANEGEGAYE 677 A + VL ++ N GE AY Sbjct: 794 DARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYS 853 Query: 678 AELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVS 737 L + + + + + C +E + +C + P + A+ +A + Sbjct: 854 TVLNISQSANLQFASLIQKEDSDGSIEC-VNEERRLQKQVCNVSYPFFR-AKAKVAFRLD 911 Query: 738 VGNLEEAGESV-----SFQLQIRSKNSQNPNSK---IVLLDVPVRAEAQVELRGNSFPAS 789 E +S+ +L S +++ ++K + L ++ EA V +S S Sbjct: 912 F----EFSKSIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHLKYEADVLFTRSS---S 964 Query: 790 LVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDI 849 L + D GP + + N G ++G+ + I +P ++ + L Sbjct: 965 LSHYEVKPNSSLERYDGIGPPFSCIFRIQNLGLFPIHGMMMKITIPIATRSGNRLL---- 1020 Query: 850 QPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLV 909 L+ F N WG + + P + D R+ P+ D V + Sbjct: 1021 ----KLRDFLTDEANTSCNIWG----NSTEYRPTPVEEDLRR----APQLNHSNSDVVSI 1068 Query: 910 SCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYA 969 +C+ + Q +L LWL SL + +A + Sbjct: 1069 NCNI-----------RLVPNQEINFHLLGNLWLRSLKALKYKSMKIMVNA---ALQRQFH 1114 Query: 970 VPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNR 1028 P + ++ + E+ +PIW ++ LGGLLLL +LVLA+WK+GFF+ R Sbjct: 1115 SPFIFREEDPSRQIVFEISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFRSAR 1173 >gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] Length = 1086 Score = 140 bits (353), Expect = 6e-33 Identities = 207/827 (25%), Positives = 340/827 (41%), Gaps = 143/827 (17%) Query: 259 PEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDS-----YYQRLHRLRG 313 PE GY GY+V T+ GAP + +G V + ++ ++ + G Sbjct: 314 PEVRAGYLGYTVTW--LPSRQKTSLLASGAPRYQH-MGRVLLFQEPQGGGHWSQVQTIHG 370 Query: 314 EQMASYFGHSVAVTDVNGDGRHDLL-VGAPL-YMESRADRKLAEVGRVYLFLQPRGPHAL 371 Q+ SYFG + DV+ DG +LL +GAPL Y E R GRV+++ + + L Sbjct: 371 TQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRG-------GRVFIYQRRQ----L 419 Query: 372 GAPSLL-LTGTQLY--GRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSE 428 G + L G Y GRFG AI L D++ DG D+AV AP +G V +F G+ Sbjct: 420 GFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFNGRHG 476 Query: 429 GLRSRPSQVLDSPFPTGSA--FGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVK 486 GL +PSQ ++ FG S+ G D++ +G D+ VGA +Q+ V ++PVV Sbjct: 477 GLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSSRPVVD 534 Query: 487 ASVQLLVQDSLNPAVK-SCVLPQTKTPVSCFNIQMCVGATGHNIPQ-----KLSLNAELQ 540 + + P + C + NI +C IPQ +L LQ Sbjct: 535 MVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKS-LIPQFQGRLVANLTYTLQ 593 Query: 541 LDRQKPRQ-----GRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSP 595 LD + R+ G R L + T+++ H P+C +D +SP Sbjct: 594 LDGHRTRRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVC------------VQDLISP 641 Query: 596 IVLSLNVSLPPTE-------AGMAPAVVLHGDTHVQE-QTRIVLDCGEDDVCVPQLQLTA 647 I +SLN SL E AG +L H + + +CGED C L+++ Sbjct: 642 INVSLNFSLWEEEGTPRDQRAGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSF 701 Query: 648 SVTGS-PLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRA-LSNVEGFERLIC 705 S S L + A L +++ +N E AY +L +H P G + + + + C Sbjct: 702 SPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSC 761 Query: 706 NQKKENE---TRVVLCELGNPM-KKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQN 761 + E +R + C + +P+ K + + M+ + G+SV + N + Sbjct: 762 EELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDS 821 Query: 762 ----PNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPK---VEHT 814 NS ++ + +P ++++ +E S GPK V+H Sbjct: 822 DLLEDNSATTIIPI-------------LYPINILIQDQEDSTLYVSFTPKGPKIHQVKHM 868 Query: 815 YELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPP-VNPLKVDWGLP 873 Y++ + QPS ++ +I + PQPP P+ W + Sbjct: 869 YQV-------------------RIQPS--IHDHNIPTLEAVVGVPQPPSEGPITHQWSVQ 907 Query: 874 IPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAM 933 + P P H +R LP+ +P P + +C + Q + Sbjct: 908 MEPPVPCHYEDLER------LPDAAEP------------CLPGALFRC---PVVFRQEIL 946 Query: 934 VTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLR--ALE 991 V V+ L L + F L S + +S + L A + +++ + Sbjct: 947 VQVIGTLELVGEIEAS-SMFSLCSSLSISFNSSKH----FHLYGSNASLAQVVMKVDVVY 1001 Query: 992 ERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEG 1038 E+ + +VL G+ GGLLLL ++ + ++KVGFFKRN L+E E G Sbjct: 1002 EKQMLYLYVLSGI-GGLLLLLLIFIVLYKVGFFKRN---LKEKMEAG 1044 >gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] Length = 1170 Score = 138 bits (348), Expect = 2e-32 Identities = 206/828 (24%), Positives = 339/828 (40%), Gaps = 144/828 (17%) Query: 259 PEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDS-----YYQRLHRLRG 313 PE GY GY+V T+ GAP + +G V + ++ ++ + G Sbjct: 397 PEVRAGYLGYTVTW--LPSRQKTSLLASGAPRYQH-MGRVLLFQEPQGGGHWSQVQTIHG 453 Query: 314 EQMASYFGHSVAVTDVNGDGRHDLL-VGAPL-YMESRADRKLAEVGRVYLFLQPRGPHAL 371 Q+ SYFG + DV+ DG +LL +GAPL Y E R GRV+++ + + L Sbjct: 454 TQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRG-------GRVFIYQRRQ----L 502 Query: 372 GAPSLL-LTGTQLY--GRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSE 428 G + L G Y GRFG AI L D++ DG D+AV AP +G V +F G+ Sbjct: 503 GFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFNGRHG 559 Query: 429 GLRSRPSQVLDSPFPTGSA--FGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVK 486 GL +PSQ ++ FG S+ G D++ +G D+ VGA +Q+ V ++PVV Sbjct: 560 GLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSSRPVVD 617 Query: 487 ASVQLLVQDSLNPAVK-SCVLPQTKTPVSCFNIQMCVGATGHNIPQ-----KLSLNAELQ 540 + + P + C + NI +C IPQ +L LQ Sbjct: 618 MVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKS-LIPQFQGRLVANLTYTLQ 676 Query: 541 LDRQKPRQ-----GRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSP 595 LD + R+ G R L + T+++ H P+C +D +SP Sbjct: 677 LDGHRTRRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVC------------VQDLISP 724 Query: 596 IVLSLNVSLPPTEA--------GMAPAVVLHGDTHVQE-QTRIVLDCGEDDVCVPQLQLT 646 I +SLN SL E G +L H + + +CGED C L+++ Sbjct: 725 INVSLNFSLWEEEGTPRDQRAQGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVS 784 Query: 647 ASVTGS-PLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRA-LSNVEGFERLI 704 S S L + A L +++ +N E AY +L +H P G + + + + Sbjct: 785 FSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVS 844 Query: 705 CNQKKENE---TRVVLCELGNPM-KKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQ 760 C + E +R + C + +P+ K + + M+ + G+SV + N Sbjct: 845 CEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNED 904 Query: 761 N----PNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPK---VEH 813 + NS ++ + +P ++++ +E S GPK V+H Sbjct: 905 SDLLEDNSATTIIPI-------------LYPINILIQDQEDSTLYVSFTPKGPKIHQVKH 951 Query: 814 TYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPP-VNPLKVDWGL 872 Y++ + QPS ++ +I + PQPP P+ W + Sbjct: 952 MYQV-------------------RIQPS--IHDHNIPTLEAVVGVPQPPSEGPITHQWSV 990 Query: 873 PIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRA 932 + P P H +R LP+ +P P + +C + Q Sbjct: 991 QMEPPVPCHYEDLER------LPDAAEP------------CLPGALFRC---PVVFRQEI 1029 Query: 933 MVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLR--AL 990 +V V+ L L + F L S + +S + L A + +++ + Sbjct: 1030 LVQVIGTLELVGEIEAS-SMFSLCSSLSISFNSSKH----FHLYGSNASLAQVVMKVDVV 1084 Query: 991 EERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEG 1038 E+ + +VL G+ GGLLLL ++ + ++KVGFFKRN L+E E G Sbjct: 1085 YEKQMLYLYVLSGI-GGLLLLLLIFIVLYKVGFFKRN---LKEKMEAG 1128 >gi|148728188 integrin, alpha E precursor [Homo sapiens] Length = 1179 Score = 130 bits (326), Expect = 8e-30 Identities = 155/577 (26%), Positives = 249/577 (43%), Gaps = 82/577 (14%) Query: 199 EAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSF---- 254 + GFS+ + +++LGA G + + G G LL+ S+ F Sbjct: 403 QIGFSAQILDERQVLLGAVGAFDWSG----------------GALLYDTRSRRGRFLNQT 446 Query: 255 -----DSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQR-- 307 D+ +Y Y GY+VAV L+ Y+ GAP + E+ + Sbjct: 447 AAAAADAEAAQY--SYLGYAVAVLHKTCSLS---YIAGAPRYKHHGAVFELQKEGREASF 501 Query: 308 LHRLRGEQMASYFGHSVAVTDVNGDGRHD-LLVGAPLYMESRADRKLAEVGRVYLFLQPR 366 L L GEQM SYFG + D++ DG D LLV AP Y E GRVY++ R Sbjct: 502 LPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVH------GEEGRVYVY---R 552 Query: 367 GPHALGAPSL--LLTGTQLY--GRFGSAIAPLGDLDRDGYNDIAVAAP---YGGPSGR-- 417 G+ SL +L+G + RFG A+A +GDL +D D+A+ AP +G G Sbjct: 553 LSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASF 612 Query: 418 GQVLVFLGQSEGLRSRPSQVL--DSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQ 475 G V ++ G +GL + PSQ + + P FG S+ G DI +G D+ VG G Q Sbjct: 613 GSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLG--Q 670 Query: 476 VAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSL 535 V+R++PVV+ V + S P + V+ CF I A+ + + L L Sbjct: 671 AVVFRSRPVVRLKVSMAFTPSALPIGFNGVV----NVRLCFEISSVTTASESGLREAL-L 725 Query: 536 NAELQLDRQKPRQGRR-------VLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEAD 588 N L +D K R+ + + L +G+ L DL + T L +E Sbjct: 726 NFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDL------LLMPTEGELCEEDC 779 Query: 589 FRDKLSPIVLSLNVSLPPTEAG-MAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTA 647 F + + + +S + P + P + + + Q C CV +LQL Sbjct: 780 FSN--ASVKVSYQLQTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLAT 837 Query: 648 SVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQ 707 +V+ L+VG L L ++ N GE +Y +A++ P+ R + C+ Sbjct: 838 TVSQQELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQLKRMQKPPS--PNIQCDD 895 Query: 708 KKENETRVVL-CELGNPMKKNAQIGIAMLVSVGNLEE 743 + + +++ C +G+P+ K + +++ V LEE Sbjct: 896 PQPVASVLIMNCRIGHPVLKRSSAHVSV---VWQLEE 929 Score = 33.5 bits (75), Expect = 1.1 Identities = 16/54 (29%), Positives = 33/54 (61%), Gaps = 2/54 (3%) Query: 973 LSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKR 1026 L+ ++ L+ + ++PI ++ G +GGLL+L ++++ ++K GFFKR Sbjct: 1103 LNAENHRTKITVVFLKDEKYHSLPI--IIKGSVGGLLVLIVILVILFKCGFFKR 1154 >gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo sapiens] Length = 462 Score = 60.1 bits (144), Expect = 1e-08 Identities = 92/439 (20%), Positives = 172/439 (39%), Gaps = 51/439 (11%) Query: 632 DCGEDDVCVPQLQLTASVTG-SPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHY 690 +CG D +C L ++ S G LLVG++ L ++ N+GE +Y + P G Y Sbjct: 19 NCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGLSY 78 Query: 691 MRALSNVEGFE----RLICNQKKENE--TRVVLCELGNPM-KKNAQIGIAMLVSVGNLEE 743 + + L C+ T C + + + + AQI V Sbjct: 79 RYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAV 138 Query: 744 AGESVSFQLQIRSKNSQNPNSKIVL-LDVPVRAEAQVELRGNSFPASLVVAAEEGEREQN 802 G+ + + S+N+ SK L++PV+ + + + +E E+E + Sbjct: 139 LGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVSSHEQFTKYLNFSESEEKESH 198 Query: 803 SLDSWGPKVEHTYELHNNGPGTVNGLH--------LSIHLPGQSQPSDLLYILDIQ---P 851 H Y+ G G++ +SI+ + + +D++ P Sbjct: 199 V-------AMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQEAVWMDVEVSHP 251 Query: 852 QGGLQCFPQPPVNPLKVD-----WGLPIPSPS------PIHPAHHKRDRRQIFLPEPEQP 900 Q C P +D W +P+ + P +P+ + +I P + Sbjct: 252 QVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSL-RCSSEKIAPPASDFL 310 Query: 901 SRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTV---LAFLWLPSLYQRPLDQFVLQS 957 + +Q ++ C A C +CD+ + + T+ L+F W+ + Q+ + + S Sbjct: 311 AHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKVS---VVS 367 Query: 958 HAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAI--PIWWVLVGVLGGLLLLTILV 1015 A + Y+ LP EA + Q LE+ + P ++ +GGLLLL ++ Sbjct: 368 VAEITFDTSVYS----QLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLALIT 423 Query: 1016 LAMWKVGFFKRNRPPLEED 1034 ++KVGFFKR + E+ Sbjct: 424 AVLYKVGFFKRQYKEMMEE 442 >gi|29171717 glycosylphosphatidylinositol specific phospholipase D1 isoform 1 precursor [Homo sapiens] Length = 840 Score = 54.3 bits (129), Expect = 6e-07 Identities = 70/248 (28%), Positives = 103/248 (41%), Gaps = 35/248 (14%) Query: 246 HVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWT----------- 294 HVSS S+ S P Y W + A DG + VVGAP +S Sbjct: 364 HVSSPLASYFLSFP-YARLGWAMTSADLNQDGH---GDLVVGAPGYSRPGHIHIGRVYLI 419 Query: 295 ----LGAVEILDSYYQRLHR-LRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRA 349 LG + + HR L G Q + FG ++AV D N DG DL VGAP S Sbjct: 420 YGNDLGLPPVDLDLDKEAHRILEGFQPSGRFGSALAVLDFNVDGVPDLAVGAP----SVG 475 Query: 350 DRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAA 409 +L G VY++ + +P++ ++ +Y G + D++ D D+ + + Sbjct: 476 SEQLTYKGAVYVYFGSKQGGMSSSPNITISCQDIYCNLGWTLL-AADVNGDSEPDLVIGS 534 Query: 410 PY--GGPSGRGQVLVF-----LGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNG 462 P+ GG +G V F L E L + S FG+SL G V +D+ Sbjct: 535 PFAPGGGKQKGIVAAFYSGPSLSDKEKLNVEAANWTVRGEEDFSWFGYSLHG-VTVDNRT 593 Query: 463 YPDLIVGA 470 L+VG+ Sbjct: 594 L--LLVGS 599 Score = 42.4 bits (98), Expect = 0.002 Identities = 105/423 (24%), Positives = 163/423 (38%), Gaps = 86/423 (20%) Query: 53 SLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGS 112 S D ++D HG +VVGAP P G V+L G P + DL E + Sbjct: 387 SADLNQDGHGD--LVVGAPGYSRPGHIHIGRVYLIYGNDLG--LPPVDLDLDKEAHRI-- 440 Query: 113 QTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTP-VGSCFLAQPESGRR 171 L+ F+ G+++ +NV + A P VGS L + Sbjct: 441 --LEGFQPSGRFGSALAVLD-----------FNVDGVPDLAVGAPSVGSEQLTY-KGAVY 486 Query: 172 AEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAG-----ELVLG---APGGYYFL 223 + +G S + S YC G++ + +LV+G APGG Sbjct: 487 VYFGSKQGGMSSSPNIT--ISCQDIYCNLGWTLLAADVNGDSEPDLVIGSPFAPGGGKQK 544 Query: 224 GLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTE 283 G++A S ++ ++ ++ E F ++GYS+ D N T Sbjct: 545 GIVAAFYSGPSLSDKEK------LNVEAANWTVRGEEDFS-WFGYSLHGVTVD---NRTL 594 Query: 284 YVVGAPTWSWTLGAVEILD------------SYY----QRLHRLRGEQMASYFGHSVAVT 327 +VG+PTW +L Y+ Q + G++ G S++ Sbjct: 595 LLVGSPTWKNASRLGHLLHIRDEKKSLGRVYGYFPPNGQSWFTISGDKAMGKLGTSLSSG 654 Query: 328 DV--NGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGA------PSLLLT 379 V NG + LLVGAP Y + +++V + + L G + A P LL T Sbjct: 655 HVLMNGTLKQVLLVGAPTYDD------VSKVAFLTVTLHQGGATRMYALTSDAQPLLLST 708 Query: 380 --GTQLYGRFGSAIAPLGDLDRDGYNDIAVAAP----------YGGPSGRGQVLVFLGQS 427 G + + RFG + L DLD DG ++I +AAP GG GR V V+ G+ Sbjct: 709 FSGDRRFSRFGGVLH-LSDLDDDGLDEIIMAAPLRIADVTSGLIGGEDGR--VYVYNGKE 765 Query: 428 EGL 430 L Sbjct: 766 TTL 768 >gi|153945755 zinc finger protein 608 [Homo sapiens] Length = 1512 Score = 34.7 bits (78), Expect = 0.48 Identities = 34/110 (30%), Positives = 50/110 (45%), Gaps = 26/110 (23%) Query: 346 ESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDG---- 401 ESR AE +VY F ++G+ S L T + G+ + +APL L ++G Sbjct: 873 ESRMASIKAEADKVYTFTDNAPSPSIGSASRLECSTLVNGQ--APMAPLHVLTQNGAESS 930 Query: 402 --------YNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSR---PSQVLDS 440 Y+DI+ AA GG R SEG+RS+ PS ++ S Sbjct: 931 AAKTSSPAYSDISDAADDGGSDSR---------SEGMRSKASSPSDIISS 971 >gi|31652264 RNA binding motif protein 26 [Homo sapiens] Length = 980 Score = 34.7 bits (78), Expect = 0.48 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 8/102 (7%) Query: 818 HNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPV-NPLKVDWGLPIPS 876 H + P V ++L LP +QP +++ P GL P PP+ P V+ P+P Sbjct: 313 HGSDPVVVEDVNLPGMLPFPAQPP----VVEGPPPPGLP--PPPPILTPPPVNLRPPVPP 366 Query: 877 PSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTV 918 P P+ P+ LP P QPS + P + S P V Sbjct: 367 PGPLPPSLPPVTGPPPPLP-PLQPSGMDAPPNSATSSVPTVV 407 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.137 0.422 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 44,257,165 Number of Sequences: 37866 Number of extensions: 2292738 Number of successful extensions: 5557 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 33 Number of HSP's successfully gapped in prelim test: 26 Number of HSP's that attempted gapping in prelim test: 5181 Number of HSP's gapped (non-prelim): 97 length of query: 1039 length of database: 18,247,518 effective HSP length: 112 effective length of query: 927 effective length of database: 14,006,526 effective search space: 12984049602 effective search space used: 12984049602 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.