Search of human proteins with 86991432

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|86991432 GLI-Kruppel family member GLI2 [Homo sapiens]
         (1586 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|86991432 GLI-Kruppel family member GLI2 [Homo sapiens]            3237   0.0  
gi|119393899 GLI-Kruppel family member GLI3 [Homo sapiens]           1177   0.0  
gi|4885279 GLI family zinc finger 1 isoform 1 [Homo sapiens]          559   e-159
gi|229892345 GLI family zinc finger 1 isoform 2 [Homo sapiens]        489   e-138
gi|109637784 GLIS family zinc finger 3 isoform a [Homo sapiens]       275   2e-73
gi|109637782 GLIS family zinc finger 3 isoform b [Homo sapiens]       275   2e-73
gi|166706915 GLIS family zinc finger 1 [Homo sapiens]                 230   7e-60
gi|110431364 GLIS family zinc finger 2 [Homo sapiens]                 194   4e-49
gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]   182   2e-45
gi|22547201 zinc finger protein of the cerebellum 4 [Homo sapiens]    181   4e-45
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]    181   7e-45
gi|4507973 zinc finger protein of the cerebellum 3 [Homo sapiens]     176   1e-43
gi|22547182 zinc finger protein of the cerebellum 1 [Homo sapiens]    176   2e-43
gi|116014328 zinc finger protein 143 [Homo sapiens]                   128   4e-29
gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]   123   2e-27
gi|115583660 zinc finger protein 391 [Homo sapiens]                   112   3e-24
gi|21361146 zinc finger protein 76 (expressed in testis) [Homo s...   111   6e-24
gi|65507817 Wilms tumor 1 isoform B [Homo sapiens]                    109   2e-23
gi|4508035 zinc finger protein 7 [Homo sapiens]                       105   3e-22
gi|117956407 zinc finger protein 568 [Homo sapiens]                   104   6e-22
gi|10863995 zinc finger protein 410 [Homo sapiens]                    103   1e-21
gi|65507714 Wilms tumor 1 isoform A [Homo sapiens]                    103   1e-21
gi|209180475 nuclear matrix transcription factor 4 isoform d [Ho...   103   1e-21
gi|239747149 PREDICTED: hypothetical protein XP_002343926 isofor...   102   2e-21
gi|239747147 PREDICTED: hypothetical protein XP_002343925 isofor...   102   2e-21
gi|239747145 PREDICTED: hypothetical protein XP_002343927 isofor...   102   2e-21
gi|55769561 zinc finger protein 21 isoform 2 [Homo sapiens]           102   2e-21
gi|55769559 zinc finger protein 21 isoform 1 [Homo sapiens]           102   2e-21
gi|188497655 zinc finger protein 84 [Homo sapiens]                    102   2e-21
gi|188497653 zinc finger protein 84 [Homo sapiens]                    102   2e-21

>gi|86991432 GLI-Kruppel family member GLI2 [Homo sapiens]
          Length = 1586

 Score = 3237 bits (8393), Expect = 0.0
 Identities = 1586/1586 (100%), Positives = 1586/1586 (100%)

Query: 1    METSASATASEKQEAKSGILEAAGFPDPGKKASPLVVAAAAAAAVAAQGVPQHLLPPFHA 60
            METSASATASEKQEAKSGILEAAGFPDPGKKASPLVVAAAAAAAVAAQGVPQHLLPPFHA
Sbjct: 1    METSASATASEKQEAKSGILEAAGFPDPGKKASPLVVAAAAAAAVAAQGVPQHLLPPFHA 60

Query: 61   PLPIDMRHQEGRYHYEPHSVHGVHGPPALSGSPVISDISLIRLSPHPAGPGESPFNAPHP 120
            PLPIDMRHQEGRYHYEPHSVHGVHGPPALSGSPVISDISLIRLSPHPAGPGESPFNAPHP
Sbjct: 61   PLPIDMRHQEGRYHYEPHSVHGVHGPPALSGSPVISDISLIRLSPHPAGPGESPFNAPHP 120

Query: 121  YVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAQEHLKERGLFGLPAPGTTPSDYYHQM 180
            YVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAQEHLKERGLFGLPAPGTTPSDYYHQM
Sbjct: 121  YVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAQEHLKERGLFGLPAPGTTPSDYYHQM 180

Query: 181  TLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDVSRFSSPRVTPRLSRKRALSISPLSD 240
            TLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDVSRFSSPRVTPRLSRKRALSISPLSD
Sbjct: 181  TLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDVSRFSSPRVTPRLSRKRALSISPLSD 240

Query: 241  ASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPAFTFPHPINPVAYQQIL 300
            ASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPAFTFPHPINPVAYQQIL
Sbjct: 241  ASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPAFTFPHPINPVAYQQIL 300

Query: 301  SQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSINATPTQLSSSSNCLSDTNQNKQSSES 360
            SQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSINATPTQLSSSSNCLSDTNQNKQSSES
Sbjct: 301  SQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSINATPTQLSSSSNCLSDTNQNKQSSES 360

Query: 361  AVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQGQVSGHGSCGCALPLSQEQLADLKED 420
            AVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQGQVSGHGSCGCALPLSQEQLADLKED
Sbjct: 361  AVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQGQVSGHGSCGCALPLSQEQLADLKED 420

Query: 421  LDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTRE 480
            LDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTRE
Sbjct: 421  LDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTRE 480

Query: 481  QKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGC 540
            QKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGC
Sbjct: 481  QKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGC 540

Query: 541  NKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQR 600
            NKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQR
Sbjct: 541  NKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQR 600

Query: 601  NDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGA 660
            NDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGA
Sbjct: 601  NDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGA 660

Query: 661  QSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLTALDDTPPGADTSALAAPSAGGLQLR 720
            QSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLTALDDTPPGADTSALAAPSAGGLQLR
Sbjct: 661  QSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLTALDDTPPGADTSALAAPSAGGLQLR 720

Query: 721  KHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRNTKLPPLPGSGSILENFSGSGGGGPA 780
            KHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRNTKLPPLPGSGSILENFSGSGGGGPA
Sbjct: 721  KHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRNTKLPPLPGSGSILENFSGSGGGGPA 780

Query: 781  GLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSSAYTVSRRSSGISPYFSSRRSSEASP 840
            GLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSSAYTVSRRSSGISPYFSSRRSSEASP
Sbjct: 781  GLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSSAYTVSRRSSGISPYFSSRRSSEASP 840

Query: 841  LGAGRPHNASSADSYDPISTDASRRSSEASQCSGGSGLLNLTPAQQYSLRAKYAAATGGP 900
            LGAGRPHNASSADSYDPISTDASRRSSEASQCSGGSGLLNLTPAQQYSLRAKYAAATGGP
Sbjct: 841  LGAGRPHNASSADSYDPISTDASRRSSEASQCSGGSGLLNLTPAQQYSLRAKYAAATGGP 900

Query: 901  PPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPLGPRRGSDGPTYGHGHAGAAPAFPHE 960
            PPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPLGPRRGSDGPTYGHGHAGAAPAFPHE
Sbjct: 901  PPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPLGPRRGSDGPTYGHGHAGAAPAFPHE 960

Query: 961  APGGGARRASDPVRRPDALSLPRVQRFHSTHNVNPGPLPPCADRRGLRLQSHPSTDGGLA 1020
            APGGGARRASDPVRRPDALSLPRVQRFHSTHNVNPGPLPPCADRRGLRLQSHPSTDGGLA
Sbjct: 961  APGGGARRASDPVRRPDALSLPRVQRFHSTHNVNPGPLPPCADRRGLRLQSHPSTDGGLA 1020

Query: 1021 RGAYSPRPPSISENVAMEAVAAGVDGAGPEADLGLPEDDLVLPDDVVQYIKAHASGALDE 1080
            RGAYSPRPPSISENVAMEAVAAGVDGAGPEADLGLPEDDLVLPDDVVQYIKAHASGALDE
Sbjct: 1021 RGAYSPRPPSISENVAMEAVAAGVDGAGPEADLGLPEDDLVLPDDVVQYIKAHASGALDE 1080

Query: 1081 GTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADSNVGPSAPMLGGCQLGFGAPSSLNKN 1140
            GTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADSNVGPSAPMLGGCQLGFGAPSSLNKN
Sbjct: 1081 GTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADSNVGPSAPMLGGCQLGFGAPSSLNKN 1140

Query: 1141 NMPVQWNEVSSGTVDALASQVKPPPFPQGNLAVVQQKPAFGQYPGYSPQGLQASPGGLDS 1200
            NMPVQWNEVSSGTVDALASQVKPPPFPQGNLAVVQQKPAFGQYPGYSPQGLQASPGGLDS
Sbjct: 1141 NMPVQWNEVSSGTVDALASQVKPPPFPQGNLAVVQQKPAFGQYPGYSPQGLQASPGGLDS 1200

Query: 1201 TQPHLQPRSGAPSQGIPRVNYMQQLRQPVAGSQCPGMTTTMSPHACYGQVHPQLSPSTIS 1260
            TQPHLQPRSGAPSQGIPRVNYMQQLRQPVAGSQCPGMTTTMSPHACYGQVHPQLSPSTIS
Sbjct: 1201 TQPHLQPRSGAPSQGIPRVNYMQQLRQPVAGSQCPGMTTTMSPHACYGQVHPQLSPSTIS 1260

Query: 1261 GALNQFPQSCSNMPAKPGHLGHPQQTEVAPDPTTMGNRHRELGVPDSALAGVPPPHPVQS 1320
            GALNQFPQSCSNMPAKPGHLGHPQQTEVAPDPTTMGNRHRELGVPDSALAGVPPPHPVQS
Sbjct: 1261 GALNQFPQSCSNMPAKPGHLGHPQQTEVAPDPTTMGNRHRELGVPDSALAGVPPPHPVQS 1320

Query: 1321 YPQQSHHLAASMSQEGYHQVPSLLPARQPGFMEPQTGPMGVATAGFGLVQPRPPLEPSPT 1380
            YPQQSHHLAASMSQEGYHQVPSLLPARQPGFMEPQTGPMGVATAGFGLVQPRPPLEPSPT
Sbjct: 1321 YPQQSHHLAASMSQEGYHQVPSLLPARQPGFMEPQTGPMGVATAGFGLVQPRPPLEPSPT 1380

Query: 1381 GRHRGVRAVQQQLAYARATGHAMAAMPSSQETAEAVPKGAMGNMGSVPPQPPPQDAGGAP 1440
            GRHRGVRAVQQQLAYARATGHAMAAMPSSQETAEAVPKGAMGNMGSVPPQPPPQDAGGAP
Sbjct: 1381 GRHRGVRAVQQQLAYARATGHAMAAMPSSQETAEAVPKGAMGNMGSVPPQPPPQDAGGAP 1440

Query: 1441 DHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQPQACQDSIQPQPLPSPGVNQVSSTV 1500
            DHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQPQACQDSIQPQPLPSPGVNQVSSTV
Sbjct: 1441 DHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQPQACQDSIQPQPLPSPGVNQVSSTV 1500

Query: 1501 DSQLLEAPQIDFDAIMDDGDHSSLFSGALSPSLLHSLSQNSSRLTTPRNSLTLPSIPAGI 1560
            DSQLLEAPQIDFDAIMDDGDHSSLFSGALSPSLLHSLSQNSSRLTTPRNSLTLPSIPAGI
Sbjct: 1501 DSQLLEAPQIDFDAIMDDGDHSSLFSGALSPSLLHSLSQNSSRLTTPRNSLTLPSIPAGI 1560

Query: 1561 SNMAVGDMSSMLTSLAEESKFLNMMT 1586
            SNMAVGDMSSMLTSLAEESKFLNMMT
Sbjct: 1561 SNMAVGDMSSMLTSLAEESKFLNMMT 1586


>gi|119393899 GLI-Kruppel family member GLI3 [Homo sapiens]
          Length = 1580

 Score = 1177 bits (3044), Expect = 0.0
 Identities = 739/1573 (46%), Positives = 927/1573 (58%), Gaps = 155/1573 (9%)

Query: 51   PQHLLPPFHAPLPIDMRHQEGRYHYEPHSVHGVHGPPALSGSPVISDISLIRLSPH--PA 108
            P HL P FH P+PID RH EGRYHY+P  +  +H   ALS SP   D+  IR+SPH  P 
Sbjct: 124  PPHLFPAFHPPVPIDARHHEGRYHYDPSPIPPLHMTSALSSSPTYPDLPFIRISPHRNPT 183

Query: 109  GPGESPFNAPHPYVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAQEHLKERGLFGLPA 168
               ESPF+ PHPY+NP+M+ Y+RS+HSSP+LSMISA RGLSP D              P 
Sbjct: 184  AASESPFSPPHPYINPYMD-YIRSLHSSPSLSMISATRGLSPTDA-------------PH 229

Query: 169  PGTTPSDYYHQMTLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDVSRFSSPRVTPRLS 228
             G +P++YYHQM L+ G  +PY D++  +  A +     +YL+ +D +RFSSPR++ R S
Sbjct: 230  AGVSPAEYYHQMALLTGQRSPYADIIPSAATAGTGAIHMEYLHAMDSTRFSSPRLSARPS 289

Query: 229  RKRALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPAFTFP 288
            RKR LSISPLSD S DLQ MIRTSPNSLV  +NNSRSSS+ASGSYGHLSA A+SPA +F 
Sbjct: 290  RKRTLSISPLSDHSFDLQTMIRTSPNSLVTILNNSRSSSSASGSYGHLSASAISPALSFT 349

Query: 289  HPINPVA---YQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSINATPTQLSSSS 345
            +   PV+   +QQILS+Q+ LGSAFGH+PPLI P+PTF  Q+P+        P Q+SS  
Sbjct: 350  YSSAPVSLHMHQQILSRQQSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLNPVQVSSGP 409

Query: 346  NCLSDTNQNKQSSESAVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQGQVSGHGSCGC 405
               S+++QNK +SESAVSST +P+  +KRSK+K + +   P +     +GQ         
Sbjct: 410  ---SESSQNKPTSESAVSSTGDPMH-NKRSKIKPDEDLPSPGA-----RGQQE------- 453

Query: 406  ALPLSQEQLADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHG 465
                  E    +KE+ D+D+ KQE EV IYETNCHWE C +E+DTQEQLVHHINN+HIHG
Sbjct: 454  ----QPEGTTLVKEEGDKDESKQEPEV-IYETNCHWEGCAREFDTQEQLVHHINNDHIHG 508

Query: 466  EKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLR 525
            EKKEFVCRW  C+REQKPFKAQYMLVVHMRRHTGEKPHKCTFEGC+KAYSRLENLKTHLR
Sbjct: 509  EKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLR 568

Query: 526  SHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHV 585
            SHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPY+CKIPGCTKRYTDPSSLRKHV
Sbjct: 569  SHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHV 628

Query: 586  KTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEAGTEPGGP------ESTEASSTSQAVED 639
            KTVHGP+AHVTKKQR D+H R P  +++G       PG P      E  + S+T+   E+
Sbjct: 629  KTVHGPEAHVTKKQRGDIHPRPPPPRDSGSHSQSRSPGRPTQGALGEQQDLSNTTSKREE 688

Query: 640  CLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLTALDD 699
            CL V+ +K E     Q SPG QSSCSS+ SP+ +  N  SG+E+P T  GS+GDL+A+D+
Sbjct: 689  CLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPISNYSN--SGLELPLTDGGSIGDLSAIDE 746

Query: 700  TPPGADTSALAAPSAGGLQLRKHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRNTKLP 759
            TP   D++   A +A  LQ R++       E +K E+LK +        P    +   + 
Sbjct: 747  TPI-MDSTISTATTALALQARRNPAGTKWMEHVKLERLKQVNGMFPRLNPILPPKAPAVS 805

Query: 760  PLPGSGSILENFSGSGGGGPAGLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSSAYTV 819
            PL G+G+   N      GGP  LLP    S+LS  +VTML+ L  RRDSS ST+SSAY  
Sbjct: 806  PLIGNGTQSNNTCSL--GGPMTLLPG--RSDLSGVDVTMLNML-NRRDSSASTISSAYLS 860

Query: 820  SRRSSGISPYFSSRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQCSGGSGLL 879
            SRRSSGISP FSSRRSSEAS    GRP N S ADSYDPISTDASRRSSEASQ  G   LL
Sbjct: 861  SRRSSGISPCFSSRRSSEASQ-AEGRPQNVSVADSYDPISTDASRRSSEASQSDGLPSLL 919

Query: 880  NLTPAQQYSLRAKYAAATGGPPPTPLPGLERMSLRTRLALL-DAPERTLPAGCPRPLGPR 938
            +LTPAQQY L+AKYAAATGGPPPTPLP +ERMSL+TRLALL DA E  +    P    PR
Sbjct: 920  SLTPAQQYRLKAKYAAATGGPPPTPLPNMERMSLKTRLALLGDALEPGV--ALPPVHAPR 977

Query: 939  RGSDGPTYGHGHAGAAPAFPHEAPGGGARRASDPVRR-PDALSLPRVQRFHSTHNVNPGP 997
            R SDG  +G+G        PH+APG G RRASDPVR   + L+LPRV RF S  + NP  
Sbjct: 978  RCSDGGAHGYGRRHLQ---PHDAPGHGVRRASDPVRTGSEGLALPRVPRFSSLSSCNPPA 1034

Query: 998  LPPCADRRGLRLQSHPSTDGGLARGAY-SPRPPSISENVAMEAVAAGVDGAGPEADLGLP 1056
            +   A++R L LQ++   +GG +R  + SP PPSI+ENV +E++         +AD  L 
Sbjct: 1035 MATSAEKRSLVLQNYTRPEGGQSRNFHSSPCPPSITENVTLESLTM-------DADANLN 1087

Query: 1057 EDDLVLPDDVVQYIKAHASGALDEGTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADSN 1116
            ++D  LPDDVVQY+ +      ++      P +S          +PGL         DS+
Sbjct: 1088 DEDF-LPDDVVQYLNSQNQAGYEQHFPSALPDDSKVPHGPGDFDAPGL--------PDSH 1138

Query: 1117 VGPSAPML-GGCQLGFGAPSSLNKNNMPVQWNEVSSGTVDALASQVKPPPFPQ------- 1168
             G     L   C  G       +K ++P+QWNEVSSG+ D  +S++K  P P        
Sbjct: 1139 AGQQFHALEQPCPEG-------SKTDLPIQWNEVSSGSADLSSSKLKCGPRPAVPQTRAF 1191

Query: 1169 ---GNLAVVQQKP-AFGQYPGYSPQGLQASP-GGLDSTQPHLQPRSGAP-----SQGIPR 1218
                 + V  Q P   G   GY   G  ++P GG +    H  P SG        Q    
Sbjct: 1192 GFCNGMVVHPQNPLRSGPAGGYQTLGENSNPYGGPEHLMLHNSPGSGTSGNAFHEQPCKA 1251

Query: 1219 VNYMQQL-RQPVAGSQCPGMTTTMSPHACYGQVH-PQLSPSTISGALNQFPQSCSNMP-A 1275
              Y   L RQPVA     G        AC   +   +L  + + G+  Q        P  
Sbjct: 1252 PQYGNCLNRQPVAPGALDG--------ACGAGIQASKLKSTPMQGSGGQLNFGLPVAPNE 1303

Query: 1276 KPGHLGHPQQTEVAPDPTTMGNRHRELGVPDSALAGVPPPHPVQSYP--QQSHHLAASMS 1333
              G + +  Q +   DP   G    +       L G    HP    P  Q    ++A+  
Sbjct: 1304 SAGSMVNGMQNQ---DPVGQGYLAHQ-------LLGDSMQHPGAGRPGQQMLGQISATSH 1353

Query: 1334 QEGYHQVPSLLPARQPGFMEPQTGPMGVATAGFGLVQPRPPLEPSPTGRHRGVRAVQQQL 1393
               Y    S LP             MG   +   +V+   P       R           
Sbjct: 1354 INIYQGPESCLPGAH---------GMGSQPSSLAVVRGYQPCASFGGSRR---------- 1394

Query: 1394 AYARATGHAMAAMPSSQETAEAVPKGAMGNMGSVPPQPPPQDAGGAPDHSMLYYYGQIHM 1453
               +A      A+ S Q +  +      G    +  QP P       ++S  +Y   +  
Sbjct: 1395 ---QAMPRDSLALQSGQLSDTSQTCRVNGIKMEMKGQPHPL-CSNLQNYSGQFYDQTVGF 1450

Query: 1454 YEQDGGLENLGSCQVM-RSQPPQPQACQDSIQPQPLPSPGVNQVSSTVDSQLLEAPQIDF 1512
             +QD      GS  +   S   Q  + ++S    P  +   + V S +DS  LE  QIDF
Sbjct: 1451 SQQD---TKAGSFSISDASCLLQGTSAKNSELLSPGANQVTSTVDS-LDSHDLEGVQIDF 1506

Query: 1513 DAIMDDGDHSSLFSGALSPSLLHSLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSML 1572
            DAI+DDGDHSSL SGALSPS++ +LS +SSRLTTPR SL  P++    +NMA+GDMSS+L
Sbjct: 1507 DAIIDDGDHSSLMSGALSPSIIQNLSHSSSRLTTPRASLPFPALSMSTTNMAIGDMSSLL 1566

Query: 1573 TSLAEESKFLNMM 1585
            TSLAEESKFL +M
Sbjct: 1567 TSLAEESKFLAVM 1579


>gi|4885279 GLI family zinc finger 1 isoform 1 [Homo sapiens]
          Length = 1106

 Score =  559 bits (1440), Expect = e-159
 Identities = 502/1442 (34%), Positives = 638/1442 (44%), Gaps = 387/1442 (26%)

Query: 165  GLPAPGT---TPSDYYHQMTLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDVSRFSSP 221
            G P+ GT   +   + HQ  L++G P  YG    ++      P             FSSP
Sbjct: 26   GAPSVGTEGLSGPPFCHQANLMSG-PHSYGPA-RETNSCTEGP------------LFSSP 71

Query: 222  RVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGAL 281
            R   +L++KRALSISPLSDASLDLQ +IRTSP+SLVA+IN+  +S    GSYGHLS G +
Sbjct: 72   RSAVKLTKKRALSISPLSDASLDLQTVIRTSPSSLVAFINSRCTSPG--GSYGHLSIGTM 129

Query: 282  SPAFTFPHPINPVAYQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSINATPTQL 341
            SP+  FP  +N          Q+G   +FG     +QP          A   +   P   
Sbjct: 130  SPSLGFPAQMN---------HQKGPSPSFG-----VQPC----GPHDSARGGMIPHPQSR 171

Query: 342  SSSSNCLSDTNQNKQSSESAVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQGQVSGHG 401
                 C     Q K   +  V             K + EP            +G +S   
Sbjct: 172  GPFPTC-----QLKSELDMLVG------------KCREEP-----------LEGDMSSPN 203

Query: 402  SCGCALPLSQEQLADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNE 461
            S G   PL    + D +EDL+R++ K+E E V YET+C W+ C++E+D+QEQLVHHIN+E
Sbjct: 204  STGIQDPLLG--MLDGREDLEREE-KREPESV-YETDCRWDGCSQEFDSQEQLVHHINSE 259

Query: 462  HIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLK 521
            HIHGE+KEFVC W  C+RE +PFKAQYMLVVHMRRHTGEKPHKCTFEGC K+YSRLENLK
Sbjct: 260  HIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLK 319

Query: 522  THLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSL 581
            THLRSHTGEKPY+CEHEGC+KAFSNASDRAKHQNRTHSNEKPY+CK+PGCTKRYTDPSSL
Sbjct: 320  THLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSL 379

Query: 582  RKHVKTVHGPDAHVTKKQRNDVHL-RTPLLKENGDSEAGTEPGGPESTEASSTSQAVEDC 640
            RKHVKTVHGPDAHVTK+ R D  L R P +            GGP   E+          
Sbjct: 380  RKHVKTVHGPDAHVTKRHRGDGPLPRAPSISTVEPKR--EREGGPIREES---------- 427

Query: 641  LHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLTALDDT 700
               R    E +   Q SPGAQSSCSS+ SP GSA N DSGVEM G   GS  DL++LD+ 
Sbjct: 428  ---RLTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGSTEDLSSLDEG 484

Query: 701  PPGADTSALAAPSAGGLQLRKHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRNTKLPP 760
            P  A T                ++T+ R E L+ ++L  L+           TR  KLP 
Sbjct: 485  PCIAGTG---------------LSTLRRLENLRLDQLHQLRPI--------GTRGLKLPS 521

Query: 761  LPGSGSILENFSGSGGGGPAGLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSSAYTVS 820
            L  +G+ +    G     P  L                     ERR SS+S++SSAYTV 
Sbjct: 522  LSHTGTTVSRRVGP----PVSL---------------------ERRSSSSSSISSAYTV- 555

Query: 821  RRSSGISPYFSSRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQCSGGSGLLN 880
                       SRRSS ASP   G P                          +G S L  
Sbjct: 556  -----------SRRSSLASPFPPGSPPE------------------------NGASSLPG 580

Query: 881  LTPAQQYSLRAKYAAAT-GGPPPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPLGPRR 939
            L PAQ Y LRA+YA+A  GG  PT    L+R+                  G P P    R
Sbjct: 581  LMPAQHYLLRARYASARGGGTSPTAASSLDRI-----------------GGLPMPPWRSR 623

Query: 940  GSDGPTYGHGHAGAAPAFPHEAPGGG-ARRASDPVRRPDALSLPRVQRFHSTHNVNPGPL 998
                             +P   P  G  RRASDP +  D  +  RVQRF S   V+    
Sbjct: 624  AE---------------YPGYNPNAGVTRRASDPAQAADRPAPARVQRFKSLGCVH---T 665

Query: 999  PPCADRRGLRLQSHPSTDGGLARGAYSPRPPSISENVAMEAVAAGVDGAGPEADLGLPED 1058
            PP     G       + D  L    YSP+PPSI+EN AM+A              GL E+
Sbjct: 666  PPTVAGGG------QNFDPYLPTSVYSPQPPSITENAAMDA-------------RGLQEE 706

Query: 1059 DLVLPDDVVQYIKAHASGALDEGTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADSNVG 1118
                P+     + +  +  +D       PT++ G+         G  G     AA    G
Sbjct: 707  ----PEVGTSMVGSGLNPYMD-----FPPTDTLGYG--------GPEG-----AAAEPYG 744

Query: 1119 PSAPMLGGCQLGFGAPSSLNKNNMPVQWNEVSSGTVDALASQVKPPPFPQGNLAVVQQKP 1178
               P  G   LG G P++   N  P Q            AS   P             + 
Sbjct: 745  ARGP--GSLPLGPGPPTNYGPNPCPQQ------------ASYPDP------------TQE 778

Query: 1179 AFGQYPGYSPQGLQASP---GGLDSTQPHLQPRSGA---PSQGIPRVNYMQQLRQPVAGS 1232
             +G++P +S  GL   P   GG  S  P L+        P QG P             GS
Sbjct: 779  TWGEFPSHS--GLYPGPKALGGTYSQCPRLEHYGQVQVKPEQGCP------------VGS 824

Query: 1233 QCPGMTTTMSPHACYGQVHPQLSPSTISGALNQFPQSCSNMPAKPGHLGHPQQTEVAPDP 1292
               G+   ++ H   G  HPQ          + +PQ     P+ P +L     T+  P P
Sbjct: 825  DSTGLAPCLNAHPSEGPPHPQ-------PLFSHYPQ-----PSPPQYLQSGPYTQ--PPP 870

Query: 1293 TTMGNRHRELGVPDSAL--AGVPPPHPVQSYPQQSHHL-------AASMSQEGYHQVPSL 1343
              + +  R     DS     G      V +Y Q    L         + +QE  +Q P  
Sbjct: 871  DYLPSEPRPCLDFDSPTHSTGQLKAQLVCNYVQSQQELLWEGGGREDAPAQEPSYQSPKF 930

Query: 1344 LPARQPGFMEPQTGPMGVATAGFG--LVQPRPPLEPSPTGRHRGVRAVQQQLAYARATGH 1401
            L   Q      +  P+     GFG  L   +    P+P+  H      +  +  A    H
Sbjct: 931  LGGSQVSPSRAK-APVNTYGPGFGPNLPNHKSGSYPTPSPCH------ENFVVGANRASH 983

Query: 1402 AMAAMPSSQETAEAVPKGAMGNMGSVPPQPPPQDAGGAPDHSMLYYYGQIHMYEQDGGLE 1461
              AA P                   +PP P                YG + +    GG  
Sbjct: 984  RAAAPPR-----------------LLPPLPT--------------CYGPLKV----GGTN 1008

Query: 1462 NLGSCQVMRSQPPQPQACQDSIQPQPLPSPGVNQVSSTVDSQLLEAPQIDFDAIMDDGDH 1521
               SC         P+  +    P   P P   QV + +DS  L+  Q+DF AI+D+   
Sbjct: 1009 --PSC-------GHPEVGRLGGGPALYPPP-EGQVCNPLDSLDLDNTQLDFVAILDEPQ- 1057

Query: 1522 SSLFSGALSPSLLHSLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEESKF 1581
                   LSP   H   + SS  T P         P+G  NMAVG+MS +L SL  E++F
Sbjct: 1058 ------GLSPPPSHD-QRGSSGHTPP---------PSGPPNMAVGNMSVLLRSLPGETEF 1101

Query: 1582 LN 1583
            LN
Sbjct: 1102 LN 1103


>gi|229892345 GLI family zinc finger 1 isoform 2 [Homo sapiens]
          Length = 978

 Score =  489 bits (1260), Expect = e-138
 Identities = 427/1210 (35%), Positives = 539/1210 (44%), Gaps = 322/1210 (26%)

Query: 394  QGQVSGHGSCGCALPLSQEQLADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQ 453
            +G +S   S G   PL    + D +EDL+R++ K+E E V YET+C W+ C++E+D+QEQ
Sbjct: 68   EGDMSSPNSTGIQDPLLG--MLDGREDLEREE-KREPESV-YETDCRWDGCSQEFDSQEQ 123

Query: 454  LVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKA 513
            LVHHIN+EHIHGE+KEFVC W  C+RE +PFKAQYMLVVHMRRHTGEKPHKCTFEGC K+
Sbjct: 124  LVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKS 183

Query: 514  YSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTK 573
            YSRLENLKTHLRSHTGEKPY+CEHEGC+KAFSNASDRAKHQNRTHSNEKPY+CK+PGCTK
Sbjct: 184  YSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTK 243

Query: 574  RYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHL-RTPLLKENGDSEAGTEPGGPESTEASS 632
            RYTDPSSLRKHVKTVHGPDAHVTK+ R D  L R P +            GGP   E+  
Sbjct: 244  RYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAPSISTVEPKR--EREGGPIREES-- 299

Query: 633  TSQAVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLG 692
                       R    E +   Q SPGAQSSCSS+ SP GSA N DSGVEM G   GS  
Sbjct: 300  -----------RLTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGSTE 348

Query: 693  DLTALDDTPPGADTSALAAPSAGGLQLRKHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPH 752
            DL++LD+ P  A T                ++T+ R E L+ ++L  L+           
Sbjct: 349  DLSSLDEGPCIAGTG---------------LSTLRRLENLRLDQLHQLRPI--------G 385

Query: 753  TRNTKLPPLPGSGSILENFSGSGGGGPAGLLPNPRLSELSASEVTMLSQLQERRDSSTST 812
            TR  KLP L  +G+ +    G     P  L                     ERR SS+S+
Sbjct: 386  TRGLKLPSLSHTGTTVSRRVGP----PVSL---------------------ERRSSSSSS 420

Query: 813  VSSAYTVSRRSSGISPYFSSRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQC 872
            +SSAYTV            SRRSS ASP   G P                          
Sbjct: 421  ISSAYTV------------SRRSSLASPFPPGSPPE------------------------ 444

Query: 873  SGGSGLLNLTPAQQYSLRAKYAAAT-GGPPPTPLPGLERMSLRTRLALLDAPERTLPAGC 931
            +G S L  L PAQ Y LRA+YA+A  GG  PT    L+R+                  G 
Sbjct: 445  NGASSLPGLMPAQHYLLRARYASARGGGTSPTAASSLDRI-----------------GGL 487

Query: 932  PRPLGPRRGSDGPTYGHGHAGAAPAFPHEAPGGG-ARRASDPVRRPDALSLPRVQRFHST 990
            P P    R                 +P   P  G  RRASDP +  D  +  RVQRF S 
Sbjct: 488  PMPPWRSRAE---------------YPGYNPNAGVTRRASDPAQAADRPAPARVQRFKSL 532

Query: 991  HNVNPGPLPPCADRRGLRLQSHPSTDGGLARGAYSPRPPSISENVAMEAVAAGVDGAGPE 1050
              V+    PP     G       + D  L    YSP+PPSI+EN AM+A           
Sbjct: 533  GCVH---TPPTVAGGG------QNFDPYLPTSVYSPQPPSITENAAMDA----------- 572

Query: 1051 ADLGLPEDDLVLPDDVVQYIKAHASGALDEGTGQVYPTESTGFSDNPRLPSPGLHGQRRM 1110
               GL E+    P+     + +  +  +D       PT++ G+         G  G    
Sbjct: 573  --RGLQEE----PEVGTSMVGSGLNPYMD-----FPPTDTLGYG--------GPEG---- 609

Query: 1111 VAADSNVGPSAPMLGGCQLGFGAPSSLNKNNMPVQWNEVSSGTVDALASQVKPPPFPQGN 1170
             AA    G   P  G   LG G P++   N  P Q            AS   P       
Sbjct: 610  -AAAEPYGARGP--GSLPLGPGPPTNYGPNPCPQQ------------ASYPDP------- 647

Query: 1171 LAVVQQKPAFGQYPGYSPQGLQASP---GGLDSTQPHLQPRSGA---PSQGIPRVNYMQQ 1224
                  +  +G++P +S  GL   P   GG  S  P L+        P QG P       
Sbjct: 648  -----TQETWGEFPSHS--GLYPGPKALGGTYSQCPRLEHYGQVQVKPEQGCP------- 693

Query: 1225 LRQPVAGSQCPGMTTTMSPHACYGQVHPQLSPSTISGALNQFPQSCSNMPAKPGHLGHPQ 1284
                  GS   G+   ++ H   G  HPQ          + +PQ     P+ P +L    
Sbjct: 694  -----VGSDSTGLAPCLNAHPSEGPPHPQ-------PLFSHYPQ-----PSPPQYLQSGP 736

Query: 1285 QTEVAPDPTTMGNRHRELGVPDSAL--AGVPPPHPVQSYPQQSHHL-------AASMSQE 1335
             T+  P P  + +  R     DS     G      V +Y Q    L         + +QE
Sbjct: 737  YTQ--PPPDYLPSEPRPCLDFDSPTHSTGQLKAQLVCNYVQSQQELLWEGGGREDAPAQE 794

Query: 1336 GYHQVPSLLPARQPGFMEPQTGPMGVATAGFG--LVQPRPPLEPSPTGRHRGVRAVQQQL 1393
              +Q P  L   Q      +  P+     GFG  L   +    P+P+  H      +  +
Sbjct: 795  PSYQSPKFLGGSQVSPSRAK-APVNTYGPGFGPNLPNHKSGSYPTPSPCH------ENFV 847

Query: 1394 AYARATGHAMAAMPSSQETAEAVPKGAMGNMGSVPPQPPPQDAGGAPDHSMLYYYGQIHM 1453
              A    H  AA P                   +PP P                YG + +
Sbjct: 848  VGANRASHRAAAPPR-----------------LLPPLPT--------------CYGPLKV 876

Query: 1454 YEQDGGLENLGSCQVMRSQPPQPQACQDSIQPQPLPSPGVNQVSSTVDSQLLEAPQIDFD 1513
                GG     SC         P+  +    P   P P   QV + +DS  L+  Q+DF 
Sbjct: 877  ----GGTN--PSC-------GHPEVGRLGGGPALYPPP-EGQVCNPLDSLDLDNTQLDFV 922

Query: 1514 AIMDDGDHSSLFSGALSPSLLHSLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLT 1573
            AI+D+          LSP   H   + SS  T P         P+G  NMAVG+MS +L 
Sbjct: 923  AILDEPQ-------GLSPPPSHD-QRGSSGHTPP---------PSGPPNMAVGNMSVLLR 965

Query: 1574 SLAEESKFLN 1583
            SL  E++FLN
Sbjct: 966  SLPGETEFLN 975


>gi|109637784 GLIS family zinc finger 3 isoform a [Homo sapiens]
          Length = 930

 Score =  275 bits (704), Expect = 2e-73
 Identities = 208/527 (39%), Positives = 257/527 (48%), Gaps = 42/527 (7%)

Query: 211 NPVDVSRFSSPRVTPRLSRKRALSISPLSDA-SLDLQRMIRTSPNSLVAYINNSRSSSAA 269
           +P    R SS R     S+KRALS+SPLSD   +D   +IRTSP SLVAYIN SR+S A 
Sbjct: 281 SPYPSPRHSSTRSHSARSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAYINGSRASPAN 340

Query: 270 SGS----YGHLSAGALSPAFTFPHPINPVAYQQILSQQRGLG-SAFGHTPPLIQPSPTFL 324
                  YGH   G        P P+ P + + +L    GL   A+G    L       L
Sbjct: 341 LSPQPEVYGHF-LGVRGSCIPQPRPV-PGSQKGVLVAPGGLALPAYGEDGALEHERMQQL 398

Query: 325 AQQPMALTSINATPTQLS-----SSSNCLSDTNQNKQSSESAVSSTVNPVAIHKRSKVKT 379
               +    +N    Q       S S  L  T + ++   S V     P           
Sbjct: 399 EHGGLQPGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPPAP---------PL 449

Query: 380 EPEGLRPASPLALTQGQVSGHGSCGCALPLSQEQLADLKEDLDRDDCKQEAEVVIYETNC 439
            P    P  P          H   G   P +Q QLA  +  LD D    E + +  +  C
Sbjct: 450 PPLPPPPGPPPPYHAHAHLHHPELG---PHAQ-QLALPQATLDDDG---EMDGIGGKHCC 502

Query: 440 HWEDCTKEYDTQEQLVHHINNEHIHGEKKE-FVCRWQACTREQKPFKAQYMLVVHMRRHT 498
            W DC+  YD QE+LV HI   HI   K E F C W  C R  KPF A+Y L++HMR H+
Sbjct: 503 RWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHS 562

Query: 499 GEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTH 558
           GEKP+KCTFEGC KA+SRLENLK HLRSHTGEKPY+C+H GC KAFSN+SDRAKHQ RTH
Sbjct: 563 GEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQ-RTH 621

Query: 559 SNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEA 618
            + KPY C+IPGCTKRYTDPSSLRKHVK     +    KK R+   L   LL +    ++
Sbjct: 622 LDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELHPDLLTDCLTVQS 681

Query: 619 GTEPGGPESTEASST---SQAVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAP 675
                 P    A  T   S      L+   I    S    S  G  +     P P+ S P
Sbjct: 682 LQPATSPRDAAAEGTVGRSPGPGPDLYSAPI---FSSNYSSRSGTAAGAVPPPHPV-SHP 737

Query: 676 NNDSGVEMPGTGPGS-LGDLTALDDTPPGADTSALAAPSAGGLQLRK 721
           +    V+     P S L  LTA+D    GA+  A +APS   +  R+
Sbjct: 738 SPGHNVQGSPHNPSSQLPPLTAVD---AGAERFAPSAPSPHHISPRR 781



 Score = 31.6 bits (70), Expect = 6.4
 Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 9/84 (10%)

Query: 1307 SALAGVPPPHPVQSYPQQSHHLAASMSQEGYHQVPSLLPAR------QPGFMEP-QTGPM 1359
            +A   VPPPHPV S+P   H++  S       Q+P L           P    P    P 
Sbjct: 723  TAAGAVPPPHPV-SHPSPGHNVQGSPHNPS-SQLPPLTAVDAGAERFAPSAPSPHHISPR 780

Query: 1360 GVATAGFGLVQPRPPLEPSPTGRH 1383
             V      L + +PP    P+G H
Sbjct: 781  RVPAPSSILQRTQPPYTQQPSGSH 804


>gi|109637782 GLIS family zinc finger 3 isoform b [Homo sapiens]
          Length = 775

 Score =  275 bits (704), Expect = 2e-73
 Identities = 208/527 (39%), Positives = 257/527 (48%), Gaps = 42/527 (7%)

Query: 211 NPVDVSRFSSPRVTPRLSRKRALSISPLSDA-SLDLQRMIRTSPNSLVAYINNSRSSSAA 269
           +P    R SS R     S+KRALS+SPLSD   +D   +IRTSP SLVAYIN SR+S A 
Sbjct: 126 SPYPSPRHSSTRSHSARSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAYINGSRASPAN 185

Query: 270 SGS----YGHLSAGALSPAFTFPHPINPVAYQQILSQQRGLG-SAFGHTPPLIQPSPTFL 324
                  YGH   G        P P+ P + + +L    GL   A+G    L       L
Sbjct: 186 LSPQPEVYGHF-LGVRGSCIPQPRPV-PGSQKGVLVAPGGLALPAYGEDGALEHERMQQL 243

Query: 325 AQQPMALTSINATPTQLS-----SSSNCLSDTNQNKQSSESAVSSTVNPVAIHKRSKVKT 379
               +    +N    Q       S S  L  T + ++   S V     P           
Sbjct: 244 EHGGLQPGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPPAP---------PL 294

Query: 380 EPEGLRPASPLALTQGQVSGHGSCGCALPLSQEQLADLKEDLDRDDCKQEAEVVIYETNC 439
            P    P  P          H   G   P +Q QLA  +  LD D    E + +  +  C
Sbjct: 295 PPLPPPPGPPPPYHAHAHLHHPELG---PHAQ-QLALPQATLDDDG---EMDGIGGKHCC 347

Query: 440 HWEDCTKEYDTQEQLVHHINNEHIHGEKKE-FVCRWQACTREQKPFKAQYMLVVHMRRHT 498
            W DC+  YD QE+LV HI   HI   K E F C W  C R  KPF A+Y L++HMR H+
Sbjct: 348 RWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHS 407

Query: 499 GEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTH 558
           GEKP+KCTFEGC KA+SRLENLK HLRSHTGEKPY+C+H GC KAFSN+SDRAKHQ RTH
Sbjct: 408 GEKPNKCTFEGCEKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQ-RTH 466

Query: 559 SNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEA 618
            + KPY C+IPGCTKRYTDPSSLRKHVK     +    KK R+   L   LL +    ++
Sbjct: 467 LDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKEQQARKKLRSSTELHPDLLTDCLTVQS 526

Query: 619 GTEPGGPESTEASST---SQAVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAP 675
                 P    A  T   S      L+   I    S    S  G  +     P P+ S P
Sbjct: 527 LQPATSPRDAAAEGTVGRSPGPGPDLYSAPI---FSSNYSSRSGTAAGAVPPPHPV-SHP 582

Query: 676 NNDSGVEMPGTGPGS-LGDLTALDDTPPGADTSALAAPSAGGLQLRK 721
           +    V+     P S L  LTA+D    GA+  A +APS   +  R+
Sbjct: 583 SPGHNVQGSPHNPSSQLPPLTAVD---AGAERFAPSAPSPHHISPRR 626



 Score = 31.6 bits (70), Expect = 6.4
 Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 9/84 (10%)

Query: 1307 SALAGVPPPHPVQSYPQQSHHLAASMSQEGYHQVPSLLPAR------QPGFMEP-QTGPM 1359
            +A   VPPPHPV S+P   H++  S       Q+P L           P    P    P 
Sbjct: 568  TAAGAVPPPHPV-SHPSPGHNVQGSPHNPS-SQLPPLTAVDAGAERFAPSAPSPHHISPR 625

Query: 1360 GVATAGFGLVQPRPPLEPSPTGRH 1383
             V      L + +PP    P+G H
Sbjct: 626  RVPAPSSILQRTQPPYTQQPSGSH 649


>gi|166706915 GLIS family zinc finger 1 [Homo sapiens]
          Length = 620

 Score =  230 bits (587), Expect = 7e-60
 Identities = 150/363 (41%), Positives = 181/363 (49%), Gaps = 68/363 (18%)

Query: 432 VVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKE-FVCRWQACTREQKPFKAQYML 490
           VV     C W DC   Y+ QE+LV HI   HI   K E F C W  C R  KPF A+Y L
Sbjct: 190 VVAGRQACRWVDCCAAYEQQEELVRHIEKSHIDQRKGEDFTCFWAGCVRRYKPFNARYKL 249

Query: 491 VVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDR 550
           ++HMR H+GEKP+KC FEGCSKA+SRLENLK HLRSHTGEKPY+C+H GC KAFSN+SDR
Sbjct: 250 LIHMRVHSGEKPNKCMFEGCSKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDR 309

Query: 551 AKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQ--RNDVHLRTP 608
           AKHQ RTH + KPY C+IPGC+KRYTDPSSLRKHVK      AH  K+Q  R  +H    
Sbjct: 310 AKHQ-RTHLDTKPYACQIPGCSKRYTDPSSLRKHVK------AHSAKEQQVRKKLH---- 358

Query: 609 LLKENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEP 668
                          GP+ TEA      + +CL ++ + T +        G    C    
Sbjct: 359 --------------AGPD-TEA----DVLTECLVLQQLHTSTQLAASDGKG---GCG--- 393

Query: 669 SPLGSAPNNDSGVEMPGTGPGSLGDLTALDD--TPPGADTSALAAPSAGGLQLRKHMTTM 726
             LG          +PG  PGS+     L     PP  D  +   P         H++ +
Sbjct: 394 --LGQE-------LLPGVYPGSITPHNGLASGLLPPAHDVPSRHHPLDATTSSHHHLSPL 444

Query: 727 HRFEQ----LKKEKLKSLKDSCSWAGPTPHTRNTKLPPLPGSGSILENFSGSGGGGPAGL 782
              E     L    L  +       GP         PPLP S       S S GG P   
Sbjct: 445 PMAESTRDGLGPGLLSPIVSPLKGLGP---------PPLPPSSQ-----SHSPGGQPFPT 490

Query: 783 LPN 785
           LP+
Sbjct: 491 LPS 493


>gi|110431364 GLIS family zinc finger 2 [Homo sapiens]
          Length = 524

 Score =  194 bits (494), Expect = 4e-49
 Identities = 91/171 (53%), Positives = 119/171 (69%), Gaps = 7/171 (4%)

Query: 439 CHWEDCTKEYDTQEQLVHHINNEHIHGEKKE-FVCRWQACTREQKPFKAQYMLVVHMRRH 497
           C W  C + ++  + LV H+N+ H+  EK   + C W+ C R  + F A+Y +++H+R H
Sbjct: 170 CRWAKCNQLFELLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTH 229

Query: 498 TGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRT 557
           T EKPH+C    CSK++SRLENLK H RSHTGEKPYVC +EGCNK +SN+SDR KH  RT
Sbjct: 230 TNEKPHRCPT--CSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKH-TRT 286

Query: 558 HSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTP 608
           H  +KPY CK+PGC KRYTDPSSLRKH+K  HG    V+ +Q+  + LR P
Sbjct: 287 HYVDKPYYCKMPGCHKRYTDPSSLRKHIK-AHG--HFVSHEQQELLQLRPP 334


>gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]
          Length = 663

 Score =  182 bits (463), Expect = 2e-45
 Identities = 89/187 (47%), Positives = 117/187 (62%), Gaps = 20/187 (10%)

Query: 444 CTKEYDTQEQLVHHINNEHIHG-EKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           C+K + T  +LV+H+  EH+ G E+   VC W+ C RE KPFKA+Y L+ H+R HTGEKP
Sbjct: 431 CSKTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKP 490

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
             C F GC K ++R ENLK H R+HTGEKP+ CE +GC++ F+N+SDR KH +  H+++K
Sbjct: 491 FPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKH-SHVHTSDK 549

Query: 563 PYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKEN--GDSEAGT 620
           PY CKI GC K YT PSSLRKH+K                +H ++P       G S  GT
Sbjct: 550 PYYCKIRGCDKSYTHPSSLRKHMK----------------IHCKSPPPSPGPLGYSSVGT 593

Query: 621 EPGGPES 627
             G P S
Sbjct: 594 PVGAPLS 600



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 46/128 (35%), Positives = 69/128 (53%), Gaps = 10/128 (7%)

Query: 439 CHWEDCTKE---YDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMR 495
           C WEDC +E   +  + +L++HI    +H  +K F C +  C    K F     L +H R
Sbjct: 460 CFWEDCPREGKPFKAKYKLINHI---RVHTGEKPFPCPFPGC---GKVFARSENLKIHKR 513

Query: 496 RHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQN 555
            HTGEKP KC F+GC + ++   + K H   HT +KPY C+  GC+K++++ S   KH  
Sbjct: 514 THTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHM- 572

Query: 556 RTHSNEKP 563
           + H    P
Sbjct: 573 KIHCKSPP 580



 Score = 37.4 bits (85), Expect = 0.12
 Identities = 61/230 (26%), Positives = 85/230 (36%), Gaps = 26/230 (11%)

Query: 928  PAGCPRPLGPRRGSDGPTYGHGHAGAA-PAFPHEAPGGGARRASDPVRRPDALSLPRVQR 986
            P     PLGP   +   T G      A PA P EAP   AR A+  V  P A S P    
Sbjct: 84   PGVATTPLGPEHMAQASTLGLSPPSQAFPAHP-EAPAAAARAAA-LVAHPGAGSYPCGGG 141

Query: 987  FHSTH-------------NVNPGPLPPCADRRGLRLQSHPSTDGGLARGAYSPRPPSISE 1033
                                +P P PP      L   +  ++ GG + G    R   +  
Sbjct: 142  SSGAQPSAPPPPAPPLPPTPSPPPPPPPPPPPALSGYTTTNSGGGGSSGKGHSRDFVLRR 201

Query: 1034 NVAMEAVAAGVDGA--GPE--ADLGLPEDDLVLPDDVVQYIKAHASGALDEGTGQVYPTE 1089
            +++  A AA + GA  G E  +  G P+     P     +I A  + A  +G+G   P  
Sbjct: 202  DLSATAPAAAMHGAPLGGEQRSGTGSPQHPAPPPHSAGMFISASGTYAGPDGSGG--PAL 259

Query: 1090 STGFSDNPRLPS---PGLHGQRRMVAADSNVGPSAPMLGGCQLGFGAPSS 1136
                 D P  P      L+GQ R+  A +    +A + G  +  F AP S
Sbjct: 260  FPALHDTPGAPGGHPHPLNGQMRLGLAAAAAAAAAELYGRAEPPF-APRS 308


>gi|22547201 zinc finger protein of the cerebellum 4 [Homo sapiens]
          Length = 334

 Score =  181 bits (460), Expect = 4e-45
 Identities = 82/148 (55%), Positives = 106/148 (71%), Gaps = 3/148 (2%)

Query: 444 CTKEYDTQEQLVHHINNEHIHG-EKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           C+K + T  +LV H+  EH+ G E+   +C W+ C R+ KPFKA+Y LV H+R HTGEKP
Sbjct: 144 CSKTFSTMHELVTHVTVEHVGGPEQANHICFWEECPRQGKPFKAKYKLVNHIRVHTGEKP 203

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
             C F GC K ++R ENLK H R+HTGEKP+ CE EGC + F+N+SDR KH +  H+++K
Sbjct: 204 FPCPFPGCGKVFARSENLKIHKRTHTGEKPFRCEFEGCERRFANSSDRKKH-SHVHTSDK 262

Query: 563 PYICKIPGCTKRYTDPSSLRKHVKTVHG 590
           PY CK+ GC K YT PSSLRKH+K VHG
Sbjct: 263 PYTCKVRGCDKCYTHPSSLRKHMK-VHG 289


>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
          Length = 532

 Score =  181 bits (458), Expect = 7e-45
 Identities = 104/268 (38%), Positives = 140/268 (52%), Gaps = 42/268 (15%)

Query: 436 ETNCHWED----------CTKEYDTQEQLVHHINNEHIHG-EKKEFVCRWQACTREQKPF 484
           E  C W D          C K + T  +LV H++ EH+ G E+   VC W+ C RE KPF
Sbjct: 255 ELICKWIDPEQLSNPKKSCNKTFSTMHELVTHVSVEHVGGPEQSNHVCFWEECPREGKPF 314

Query: 485 KAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAF 544
           KA+Y LV H+R HTGEKP  C F GC K ++R ENLK H R+HTGEKP+ CE EGC++ F
Sbjct: 315 KAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRF 374

Query: 545 SNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVH 604
           +N+SDR KH +  H+++KPY+CK+  C K YT PSSLRKH+K                VH
Sbjct: 375 ANSSDRKKHMH-VHTSDKPYLCKM--CDKSYTHPSSLRKHMK----------------VH 415

Query: 605 LRTPLLKENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGAQSSC 664
             +P   +  +S      G   ST     S + E          +SS     +  A ++ 
Sbjct: 416 ESSP---QGSESSPAASSGYESSTPPGLVSPSAE---------PQSSSNLSPAAAAAAAA 463

Query: 665 SSEPSPLGSAPNNDSGVEMPGTGPGSLG 692
           ++  +   SA +   G    G G GS G
Sbjct: 464 AAAAAAAVSAVHRGGGSGSGGAGGGSGG 491



 Score = 32.7 bits (73), Expect = 2.9
 Identities = 17/49 (34%), Positives = 25/49 (51%)

Query: 2   ETSASATASEKQEAKSGILEAAGFPDPGKKASPLVVAAAAAAAVAAQGV 50
           E+S +A++  +     G++  +  P      SP   AAAAAAA AA  V
Sbjct: 423 ESSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAV 471


>gi|4507973 zinc finger protein of the cerebellum 3 [Homo sapiens]
          Length = 467

 Score =  176 bits (447), Expect = 1e-43
 Identities = 89/207 (42%), Positives = 120/207 (57%), Gaps = 14/207 (6%)

Query: 436 ETNCHWED----------CTKEYDTQEQLVHHINNEHIHG-EKKEFVCRWQACTREQKPF 484
           E +C W D          C + + T  +LV H+  EH+ G E+   VC W+ C RE K F
Sbjct: 250 ELSCKWIDEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWEECPREGKSF 309

Query: 485 KAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAF 544
           KA+Y LV H+R HTGEKP  C F GC K ++R ENLK H R+HTGEKP+ CE EGC++ F
Sbjct: 310 KAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRF 369

Query: 545 SNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVH 604
           +N+SDR KH +  H+++KPYICK+  C K YT PSSLRKH+K      +  +    +   
Sbjct: 370 ANSSDRKKHMH-VHTSDKPYICKV--CDKSYTHPSSLRKHMKVHESQGSDSSPAASSGYE 426

Query: 605 LRTPLLKENGDSEAGTEPGGPESTEAS 631
             TP    + +S+  T+      T  S
Sbjct: 427 SSTPPAIASANSKDTTKTPSAVQTSTS 453


>gi|22547182 zinc finger protein of the cerebellum 1 [Homo sapiens]
          Length = 447

 Score =  176 bits (446), Expect = 2e-43
 Identities = 79/146 (54%), Positives = 104/146 (71%), Gaps = 4/146 (2%)

Query: 442 EDCTKEYDTQEQLVHHINNEHIHG-EKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGE 500
           + C K + T  +LV H+  EH+ G E+   +C W+ C RE KPFKA+Y LV H+R HTGE
Sbjct: 240 KSCNKTFSTMHELVTHVTVEHVGGPEQSNHICFWEECPREGKPFKAKYKLVNHIRVHTGE 299

Query: 501 KPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSN 560
           KP  C F GC K ++R ENLK H R+HTGEKP+ CE EGC++ F+N+SDR KH +  H++
Sbjct: 300 KPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMH-VHTS 358

Query: 561 EKPYICKIPGCTKRYTDPSSLRKHVK 586
           +KPY+CK+  C K YT PSSLRKH+K
Sbjct: 359 DKPYLCKM--CDKSYTHPSSLRKHMK 382



 Score = 90.9 bits (224), Expect = 9e-18
 Identities = 45/127 (35%), Positives = 70/127 (55%), Gaps = 11/127 (8%)

Query: 439 CHWEDCTKE---YDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMR 495
           C WE+C +E   +  + +LV+HI    +H  +K F C +  C    K F     L +H R
Sbjct: 271 CFWEECPREGKPFKAKYKLVNHI---RVHTGEKPFPCPFPGC---GKVFARSENLKIHKR 324

Query: 496 RHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQN 555
            HTGEKP KC FEGC + ++   + K H+  HT +KPY+C+   C+K++++ S   KH  
Sbjct: 325 THTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKM--CDKSYTHPSSLRKHMK 382

Query: 556 RTHSNEK 562
              S+ +
Sbjct: 383 VHESSSQ 389



 Score = 48.5 bits (114), Expect = 5e-05
 Identities = 44/184 (23%), Positives = 73/184 (39%), Gaps = 19/184 (10%)

Query: 508 EGCSKAYSRLENLKTHLR-SHTG---EKPYVCEHEGCNKAFSNASDRAKHQN--RTHSNE 561
           + C+K +S +  L TH+   H G   +  ++C  E C +       + K  N  R H+ E
Sbjct: 240 KSCNKTFSTMHELVTHVTVEHVGGPEQSNHICFWEECPREGKPFKAKYKLVNHIRVHTGE 299

Query: 562 KPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAH------VTKKQRNDVHLRTPLLKENGD 615
           KP+ C  PGC K +    +L+ H +T  G            ++  N    +  +     D
Sbjct: 300 KPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSD 359

Query: 616 SEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAP 675
                +      T  SS  +      H++  ++ S G  Q SP A S   S   P   +P
Sbjct: 360 KPYLCKMCDKSYTHPSSLRK------HMKVHESSSQG-SQPSPAASSGYESSTPPTIVSP 412

Query: 676 NNDS 679
           + D+
Sbjct: 413 STDN 416


>gi|116014328 zinc finger protein 143 [Homo sapiens]
          Length = 638

 Score =  128 bits (322), Expect = 4e-29
 Identities = 62/146 (42%), Positives = 85/146 (58%), Gaps = 7/146 (4%)

Query: 439 CHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHT 498
           C    C K + T   L  H+     H  +K + C    CT   K FK    L  H+R HT
Sbjct: 269 CEHAGCGKAFATGYGLKSHVRT---HTGEKPYRCSEDNCT---KSFKTSGDLQKHIRTHT 322

Query: 499 GEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTH 558
           GE+P KC FEGC ++++     K H+R+HTGE+PY C   GC +AF++A++   H  R H
Sbjct: 323 GERPFKCPFEGCGRSFTTSNIRKVHVRTHTGERPYYCTEPGCGRAFASATNYKNHV-RIH 381

Query: 559 SNEKPYICKIPGCTKRYTDPSSLRKH 584
           + EKPY+C +PGC KR+T+ SSL KH
Sbjct: 382 TGEKPYVCTVPGCDKRFTEYSSLYKH 407



 Score =  117 bits (292), Expect = 1e-25
 Identities = 55/157 (35%), Positives = 87/157 (55%), Gaps = 7/157 (4%)

Query: 439 CHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHT 498
           C ++ C K Y T   L  H   E  H   + + C    C    K F   Y L  H+R HT
Sbjct: 239 CEYDGCGKLYTTAHHLKVH---ERSHTGDRPYQCEHAGCG---KAFATGYGLKSHVRTHT 292

Query: 499 GEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTH 558
           GEKP++C+ + C+K++    +L+ H+R+HTGE+P+ C  EGC ++F+ ++ R  H  RTH
Sbjct: 293 GEKPYRCSEDNCTKSFKTSGDLQKHIRTHTGERPFKCPFEGCGRSFTTSNIRKVHV-RTH 351

Query: 559 SNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHV 595
           + E+PY C  PGC + +   ++ + HV+   G   +V
Sbjct: 352 TGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYV 388



 Score =  107 bits (267), Expect = 9e-23
 Identities = 49/124 (39%), Positives = 73/124 (58%), Gaps = 4/124 (3%)

Query: 467 KKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRS 526
           +K F C +  C    K +   + L VH R HTG++P++C   GC KA++    LK+H+R+
Sbjct: 234 EKAFRCEYDGCG---KLYTTAHHLKVHERSHTGDRPYQCEHAGCGKAFATGYGLKSHVRT 290

Query: 527 HTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVK 586
           HTGEKPY C  + C K+F  + D  KH  RTH+ E+P+ C   GC + +T  +  + HV+
Sbjct: 291 HTGEKPYRCSEDNCTKSFKTSGDLQKH-IRTHTGERPFKCPFEGCGRSFTTSNIRKVHVR 349

Query: 587 TVHG 590
           T  G
Sbjct: 350 THTG 353



 Score =  103 bits (257), Expect = 1e-21
 Identities = 59/157 (37%), Positives = 77/157 (49%), Gaps = 9/157 (5%)

Query: 440 HWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHT- 498
           H  D T + DT   L  +     I G   E V         ++  K Q +L  H  R T 
Sbjct: 170 HTGDATIDPDTISALEQYAAKVSIDGS--ESVAGTGMIGENEQEKKMQIVLQGHATRVTA 227

Query: 499 -----GEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKH 553
                GEK  +C ++GC K Y+   +LK H RSHTG++PY CEH GC KAF+       H
Sbjct: 228 KSQQSGEKAFRCEYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHAGCGKAFATGYGLKSH 287

Query: 554 QNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHG 590
             RTH+ EKPY C    CTK +     L+KH++T  G
Sbjct: 288 V-RTHTGEKPYRCSEDNCTKSFKTSGDLQKHIRTHTG 323



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 44/152 (28%), Positives = 64/152 (42%), Gaps = 32/152 (21%)

Query: 439 CHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTRE----------------QK 482
           C  ++CTK + T   L  HI     H  ++ F C ++ C R                 ++
Sbjct: 299 CSEDNCTKSFKTSGDLQKHIRT---HTGERPFKCPFEGCGRSFTTSNIRKVHVRTHTGER 355

Query: 483 P-----------FKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEK 531
           P           F +      H+R HTGEKP+ CT  GC K ++   +L  H   HT  K
Sbjct: 356 PYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRFTEYSSLYKHHVVHTHSK 415

Query: 532 PYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 563
           PY C H  C K +   S  A H+   H++ +P
Sbjct: 416 PYNCNH--CGKTYKQISTLAMHKRTAHNDTEP 445


>gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]
          Length = 753

 Score =  123 bits (308), Expect = 2e-27
 Identities = 89/302 (29%), Positives = 136/302 (45%), Gaps = 28/302 (9%)

Query: 423 RDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQK 482
           + +C +     +    C +E C + Y T   L  H   +  H  +  FVC  + C    K
Sbjct: 126 QSECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTH---QKTHRGEYTFVCNQEGC---GK 179

Query: 483 PFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNK 542
            F   Y L +H+R HT EKP +C  +GC KA++ L  LK H R HTG K + CE EGC+K
Sbjct: 180 AFLTSYSLRIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTG-KTFNCESEGCSK 238

Query: 543 AFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHG------PDAHVT 596
            F+  SD  KH  RTH+ EKP+ C   GC K +     L+ HV+T  G      P     
Sbjct: 239 YFTTLSDLRKH-IRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCE 297

Query: 597 KKQRNDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTESSGLCQS 656
           K       L++ +  +  D++  +    P+   +  T+ ++  CL   ++ +  S L ++
Sbjct: 298 KTFSTQYSLKSHM--KGHDNKGHSYNALPQHNGSEDTNHSL--CLSDLSLLSTDSELREN 353

Query: 657 SPGAQSSCSSEPSPL-----GSAPNNDSGVEMPGTGPGSL-----GDLTALDDTPPGADT 706
           S   Q    S  SP          ++D+ ++       SL     GD  ++ D PP    
Sbjct: 354 SSTTQGQDLSTISPAIIFESMFQNSDDTAIQEDPQQTASLTESFNGDAESVSDVPPSTGN 413

Query: 707 SA 708
           SA
Sbjct: 414 SA 415



 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 129/500 (25%), Positives = 190/500 (38%), Gaps = 70/500 (14%)

Query: 439 CHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHT 498
           C  + C K ++T  +L  H   + +H   K F C  + C+   K F     L  H+R HT
Sbjct: 202 CDVQGCEKAFNTLYRLKAH---QRLH-TGKTFNCESEGCS---KYFTTLSDLRKHIRTHT 254

Query: 499 GEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSN----ASDRAKHQ 554
           GEKP +C  +GC KA++   +LKTH+R+HTGE+P+ C   GC K FS      S    H 
Sbjct: 255 GEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQYSLKSHMKGHD 314

Query: 555 NRTHS-NEKPY----------ICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDV 603
           N+ HS N  P           +C +   +   TD S LR++  T  G D           
Sbjct: 315 NKGHSYNALPQHNGSEDTNHSLC-LSDLSLLSTD-SELRENSSTTQGQDLSTISPA---- 368

Query: 604 HLRTPLLKENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAI--KTESSGLCQSSPGAQ 661
            +    + +N D  A  E   P+ T AS T     D   V  +   T +S         Q
Sbjct: 369 -IIFESMFQNSDDTAIQE--DPQQT-ASLTESFNGDAESVSDVPPSTGNSASLSLPLVLQ 424

Query: 662 SSCSSEPSPLGSAPNNDSGVEMPGTGPGS----LGDLTALDDTP--PGADTSALAAPSAG 715
              S  P PL  A    +    P  GPGS     G+  AL   P  P   ++  AA    
Sbjct: 425 PGLSEPPQPLLPASAPSAPPPAPSLGPGSQQAAFGNPPALLQPPEVPVPHSTQFAANHQE 484

Query: 716 GL-QLRKHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRNTKLPPLP--------GSGS 766
            L   +     +     +      +   + + A P P    T+  PLP        G+ S
Sbjct: 485 FLPHPQAPQPIVPGLSVVAGASASAAAVASAVAAPAPPQSTTE--PLPAMVQTLPLGANS 542

Query: 767 ILENFSGSGGGGPAGLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSSAYTVSRRSSGI 826
           +L N           + P P  + L +S V     LQ   + +TS+  +   + + S   
Sbjct: 543 VLTN------NPTITITPTPNTAILQSSLVMGEQNLQWILNGATSSPQNQEQIQQASKVE 596

Query: 827 SPYFSSRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQCSGGSGLLNLTPAQQ 886
             +F++     +SP         SS             +  EA QC         +  ++
Sbjct: 597 KVFFTTAVPVASSP--------GSSVQQIGLSVPVIIIKQEEACQCQCA---CRDSAKER 645

Query: 887 YSLRAKYAAATGGPPPTPLP 906
            S R K    +  PPP P P
Sbjct: 646 ASSRRK--GCSSPPPPEPSP 663



 Score = 32.3 bits (72), Expect = 3.7
 Identities = 24/99 (24%), Positives = 36/99 (36%), Gaps = 7/99 (7%)

Query: 503 HKCTFEGCSKAYSR--LENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSN 560
           H    E  S+ Y +  +   + HL  + G  P     EG      +     K +      
Sbjct: 82  HLIDHEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEGATLTLQSECPETKRKE----- 136

Query: 561 EKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQ 599
            K Y C   GC + Y+   +LR H KT  G    V  ++
Sbjct: 137 VKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQE 175


>gi|115583660 zinc finger protein 391 [Homo sapiens]
          Length = 358

 Score =  112 bits (280), Expect = 3e-24
 Identities = 86/261 (32%), Positives = 123/261 (47%), Gaps = 32/261 (12%)

Query: 340 QLSSSSNCLSDTNQNKQSSESAVSSTVNPVAIHKRSKVKTEPEGLR-PASPLALTQGQV- 397
           QLS  + C +   Q K S E+ V   V+ V + +    +  PE      SP    Q ++ 
Sbjct: 23  QLSRQTKCPA---QKKSSFENTVVRKVS-VTLKEIFTGEEGPESSEFSLSPNLDAQQKIP 78

Query: 398 SGHGSCGCALPLSQEQLADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHH 457
            GHGS     P+S+      K   D  D  +   +      C   +C K +  Q  L+ H
Sbjct: 79  KGHGS-----PISR------KNSKDNSDLIKHQRLFSQRKPCKCNECEKAFSYQSDLLVH 127

Query: 458 INNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRL 517
                IHG +K F      C +  K F     L+ H R HTGEKP++C    C KA+SR 
Sbjct: 128 ---SRIHGGEKPF-----ECNKCGKSFSRSTHLIEHQRTHTGEKPYECN--ECGKAFSRS 177

Query: 518 ENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTD 577
            +L  H R HTGEKPY C    C KAFS +++ ++HQ RTH+ E+PY C    C K + D
Sbjct: 178 THLSLHQRIHTGEKPYECSE--CGKAFSRSTNLSQHQ-RTHTQERPYKCN--ECGKAFGD 232

Query: 578 PSSLRKHVKTVHGPDAHVTKK 598
            S++ +H +   G + +   K
Sbjct: 233 RSTIIQHQRIHTGENPYECSK 253



 Score = 89.4 bits (220), Expect = 3e-17
 Identities = 53/148 (35%), Positives = 78/148 (52%), Gaps = 15/148 (10%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           +C K +     L  H   +  H +++ + C    C    K F  +  ++ H R HTGE P
Sbjct: 197 ECGKAFSRSTNLSQH---QRTHTQERPYKCN--ECG---KAFGDRSTIIQHQRIHTGENP 248

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
           ++C+   C KA+S + +L  H R+HTGE PY C    C K FS +S   +HQ R HS EK
Sbjct: 249 YECS--KCGKAFSWISSLTEHQRTHTGENPYECSE--CGKVFSRSSSLTEHQ-RIHSGEK 303

Query: 563 PYICKIPGCTKRYTDPSSLRKHVKTVHG 590
           P+ C++  C K ++  SSL  H +T  G
Sbjct: 304 PHECRV--CGKGFSRSSSLIIHQRTHTG 329



 Score = 84.3 bits (207), Expect = 8e-16
 Identities = 50/142 (35%), Positives = 72/142 (50%), Gaps = 15/142 (10%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           +C K +  +  ++ H   + IH  +  +      C++  K F     L  H R HTGE P
Sbjct: 225 ECGKAFGDRSTIIQH---QRIHTGENPY-----ECSKCGKAFSWISSLTEHQRTHTGENP 276

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
           ++C+   C K +SR  +L  H R H+GEKP+ C    C K FS +S    HQ RTH+ EK
Sbjct: 277 YECS--ECGKVFSRSSSLTEHQRIHSGEKPHECRV--CGKGFSRSSSLIIHQ-RTHTGEK 331

Query: 563 PYICKIPGCTKRYTDPSSLRKH 584
           PY C    C K +   S+L +H
Sbjct: 332 PYKCN--DCGKAFCQSSTLIRH 351



 Score = 70.9 bits (172), Expect = 9e-12
 Identities = 46/140 (32%), Positives = 61/140 (43%), Gaps = 13/140 (9%)

Query: 422 DRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQ 481
           DR    Q   +   E       C K +     L  H   +  H  +  +      C+   
Sbjct: 232 DRSTIIQHQRIHTGENPYECSKCGKAFSWISSLTEH---QRTHTGENPY-----ECSECG 283

Query: 482 KPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCN 541
           K F     L  H R H+GEKPH+C    C K +SR  +L  H R+HTGEKPY C    C 
Sbjct: 284 KVFSRSSSLTEHQRIHSGEKPHECRV--CGKGFSRSSSLIIHQRTHTGEKPYKC--NDCG 339

Query: 542 KAFSNASDRAKHQNRTHSNE 561
           KAF  +S   +HQ+  H+ E
Sbjct: 340 KAFCQSSTLIRHQH-LHTKE 358


>gi|21361146 zinc finger protein 76 (expressed in testis) [Homo
           sapiens]
          Length = 570

 Score =  111 bits (277), Expect = 6e-24
 Identities = 76/242 (31%), Positives = 110/242 (45%), Gaps = 17/242 (7%)

Query: 439 CHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHT 498
           C  E C+K + T   L  H+     H  ++ F C ++ C R    F    +  VH+R HT
Sbjct: 227 CPEELCSKAFKTSGDLQKHVRT---HTGERPFQCPFEGCGRS---FTTSNIRKVHVRTHT 280

Query: 499 GEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTH 558
           GE+P+ C    C + ++   N K H+R HTGEKPYVC   GC K F+  S   KH +  H
Sbjct: 281 GERPYTCPEPHCGRGFTSATNYKNHVRIHTGEKPYVCTVPGCGKRFTEYSSLYKH-HVVH 339

Query: 559 SNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEA 618
           ++ KPY C    C K Y   S+L  H ++ HG +   T++    ++     L+    +E 
Sbjct: 340 THCKPYTCST--CGKTYRQTSTLAMHKRSAHG-ELEATEESEQALY-EQQQLEAASAAEE 395

Query: 619 GTEPGGPESTEASSTSQAVEDCLHVRAIKTESSGLCQ----SSPGAQ--SSCSSEPSPLG 672
              P  P     S   +  +D     A+ TE  G  Q    +  GAQ  S    +   LG
Sbjct: 396 SPPPKRPRIAYLSEVKEERDDIPAQVAMVTEEDGAPQVALITQDGAQQVSLSPEDLQALG 455

Query: 673 SA 674
           SA
Sbjct: 456 SA 457



 Score =  108 bits (270), Expect = 4e-23
 Identities = 61/173 (35%), Positives = 92/173 (53%), Gaps = 12/173 (6%)

Query: 468 KEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSH 527
           + F C ++ C R    +   + L VH R HTG++P++C F  C KA++    LK+H+R+H
Sbjct: 163 RAFRCGYKGCGRL---YTTAHHLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHVRTH 219

Query: 528 TGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKT 587
           TGEKPY C  E C+KAF  + D  KH  RTH+ E+P+ C   GC + +T  +  + HV+T
Sbjct: 220 TGEKPYKCPEELCSKAFKTSGDLQKHV-RTHTGERPFQCPFEGCGRSFTTSNIRKVHVRT 278

Query: 588 VHG------PDAHVTKKQRNDVHLRTPLLKENGDSE-AGTEPG-GPESTEASS 632
             G      P+ H  +   +  + +  +    G+     T PG G   TE SS
Sbjct: 279 HTGERPYTCPEPHCGRGFTSATNYKNHVRIHTGEKPYVCTVPGCGKRFTEYSS 331



 Score = 83.6 bits (205), Expect = 1e-15
 Identities = 36/95 (37%), Positives = 55/95 (57%), Gaps = 1/95 (1%)

Query: 496 RHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQN 555
           +  G++  +C ++GC + Y+   +LK H R+HTG++PY C+   C KAF+       H  
Sbjct: 158 QQVGDRAFRCGYKGCGRLYTTAHHLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHV- 216

Query: 556 RTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHG 590
           RTH+ EKPY C    C+K +     L+KHV+T  G
Sbjct: 217 RTHTGEKPYKCPEELCSKAFKTSGDLQKHVRTHTG 251


>gi|65507817 Wilms tumor 1 isoform B [Homo sapiens]
          Length = 514

 Score =  109 bits (272), Expect = 2e-23
 Identities = 117/465 (25%), Positives = 176/465 (37%), Gaps = 78/465 (16%)

Query: 139 LSMISAARGLSPADVAQEHLKERGLFGLPAPGTTPSDYYHQMTLVAGHPAPYGDLLMQSG 198
           L +  AA+     D A       G  G PAP   P             P P+  +  +  
Sbjct: 94  LPVSGAAQWAPVLDFAPPGASAYGSLGGPAPPPAPPP--------PPPPPPHSFIKQEPS 145

Query: 199 GAASAPHLHDYLNPVDVSRFSSPRVTPRLSRKRALSISPLSDASLDLQRMIRTSP----- 253
              + PH    L+   V        T    R       P S AS    RM   +P     
Sbjct: 146 WGGAEPHEEQCLSAFTVHFSGQFTGTAGACRYGPFGPPPPSQASSGQARMFPNAPYLPSC 205

Query: 254 -NSLVAYINNSRSSSAASG--SYGHLSA--GALSPAFTFPHPINPVAYQQILSQQRGLGS 308
             S  A  N   S+    G  SYGH  +   A  P  +F H       +  + QQ  LG 
Sbjct: 206 LESQPAIRNQGYSTVTFDGTPSYGHTPSHHAAQFPNHSFKH-------EDPMGQQGSLGE 258

Query: 309 AFGHTPPLIQ----PSPTFLAQQPMALTSINATPT--QLSSSSNCLSDTNQNKQSSESAV 362
                PP +     P+ +    Q + L +  ++    Q++S   C++    N       +
Sbjct: 259 QQYSVPPPVYGCHTPTDSCTGSQALLLRTPYSSDNLYQMTSQLECMTWNQMN-------L 311

Query: 363 SSTVNPVAIHKRSKVKTEPEGLRPASPLALTQGQVS---GHGSCGCALPLSQEQLADLKE 419
            +T+  VA    S VK              T+GQ +   G+ S     P+          
Sbjct: 312 GATLKGVAAGSSSSVKW-------------TEGQSNHSTGYESDNHTTPIL--------- 349

Query: 420 DLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTR 479
                 C  +  +  +      +D  +       LV   +      EK+ F+C +  C +
Sbjct: 350 ------CGAQYRIHTHGVFRGIQDVRRVPGVAPTLVRSASET---SEKRPFMCAYPGCNK 400

Query: 480 EQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEG 539
               FK  + L +H R+HTGEKP++C F+ C + +SR + LK H R HTG KP+ C  + 
Sbjct: 401 RY--FKLSH-LQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQC--KT 455

Query: 540 CNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKH 584
           C + FS  SD  K   RTH+ EKP+ C+ P C K++     L +H
Sbjct: 456 CQRKFSR-SDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRH 499



 Score = 80.9 bits (198), Expect = 9e-15
 Identities = 39/101 (38%), Positives = 57/101 (56%), Gaps = 4/101 (3%)

Query: 491 VVHMRRHTGEK-PHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASD 549
           +V     T EK P  C + GC+K Y +L +L+ H R HTGEKPY C+ + C + FS  SD
Sbjct: 378 LVRSASETSEKRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSR-SD 436

Query: 550 RAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHG 590
           + K   R H+  KP+ CK   C ++++    L+ H +T  G
Sbjct: 437 QLKRHQRRHTGVKPFQCKT--CQRKFSRSDHLKTHTRTHTG 475


>gi|4508035 zinc finger protein 7 [Homo sapiens]
          Length = 686

 Score =  105 bits (263), Expect = 3e-22
 Identities = 65/169 (38%), Positives = 87/169 (51%), Gaps = 21/169 (12%)

Query: 435 YETNCHWE------DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQY 488
           +  NCH E      +C K +    QL  H   + IH  +K F      CT   K F+   
Sbjct: 240 HTNNCHGEKPYECAECGKVFRLCSQLNQH---QRIHTGEKPF-----KCTECGKAFRLSS 291

Query: 489 MLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNAS 548
            L+ H R HTGEKP++C  E C KA+ +  +L  H R HTGE+PY C    C KAFS  S
Sbjct: 292 KLIQHQRIHTGEKPYRC--EECGKAFGQSSSLIHHQRIHTGERPYGCRE--CGKAFSQQS 347

Query: 549 DRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTK 597
              +HQ RTH+ E+PY CK   C K ++  S+L +H +   G  A + K
Sbjct: 348 QLVRHQ-RTHTGERPYPCK--ECGKAFSQSSTLAQHQRMHTGEKAQILK 393



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 51/133 (38%), Positives = 68/133 (51%), Gaps = 12/133 (9%)

Query: 458 INNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRL 517
           + ++ IH  +K F C    C    K F+    L  H   HTGEKP+KC    C+KA+   
Sbjct: 401 VAHQRIHAVEKPFKC--DECG---KAFRWISRLSQHQLIHTGEKPYKCN--KCTKAFGCS 453

Query: 518 ENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTD 577
             L  H R+HTGEKP+ C+   C K F   S   +HQ R H+ EKPY+C    C K ++ 
Sbjct: 454 SRLIRHQRTHTGEKPFKCDE--CGKGFVQGSHLIQHQ-RIHTGEKPYVCN--DCGKAFSQ 508

Query: 578 PSSLRKHVKTVHG 590
            SSL  H +   G
Sbjct: 509 SSSLIYHQRIHKG 521



 Score = 81.6 bits (200), Expect = 5e-15
 Identities = 61/199 (30%), Positives = 84/199 (42%), Gaps = 31/199 (15%)

Query: 442 EDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEK 501
           ++C K +     L+ H   + IH  +K +VC    C    K F     L+ H R H GEK
Sbjct: 472 DECGKGFVQGSHLIQH---QRIHTGEKPYVCN--DCG---KAFSQSSSLIYHQRIHKGEK 523

Query: 502 PHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNE 561
           P++C    C KA+S    L  H R HTGE+PY C    C KAFS  S   +HQ   H+  
Sbjct: 524 PYECL--QCGKAFSMSTQLTIHQRVHTGERPYKCNE--CGKAFSQNSTLFQHQ-IIHAGV 578

Query: 562 KPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEAGTE 621
           KPY C    C K ++  S L +H +                +H R     E G++  G+ 
Sbjct: 579 KPYECS--ECGKAFSRSSYLIEHQR----------------IHTRAQWFYEYGNALEGST 620

Query: 622 PGGPESTEASSTSQAVEDC 640
               +           EDC
Sbjct: 621 FVSRKKVNTIKKLHQCEDC 639



 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 56/171 (32%), Positives = 75/171 (43%), Gaps = 28/171 (16%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYM------------- 489
           +C K +  Q QLV H   +  H  ++ + C+       Q    AQ+              
Sbjct: 338 ECGKAFSQQSQLVRH---QRTHTGERPYPCKECGKAFSQSSTLAQHQRMHTGEKAQILKA 394

Query: 490 -----LVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAF 544
                LV H R H  EKP KC  + C KA+  +  L  H   HTGEKPY C    C KAF
Sbjct: 395 SDSPSLVAHQRIHAVEKPFKC--DECGKAFRWISRLSQHQLIHTGEKPYKCNK--CTKAF 450

Query: 545 SNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHV 595
             +S   +HQ RTH+ EKP+ C    C K +   S L +H +   G   +V
Sbjct: 451 GCSSRLIRHQ-RTHTGEKPFKC--DECGKGFVQGSHLIQHQRIHTGEKPYV 498



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 54/196 (27%), Positives = 71/196 (36%), Gaps = 66/196 (33%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           DC K +     L++H   + IH  +K +      C +  K F     L +H R HTGE+P
Sbjct: 501 DCGKAFSQSSSLIYH---QRIHKGEKPY-----ECLQCGKAFSMSTQLTIHQRVHTGERP 552

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQN------- 555
           +KC    C KA+S+   L  H   H G KPY C    C KAFS +S   +HQ        
Sbjct: 553 YKCN--ECGKAFSQNSTLFQHQIIHAGVKPYECSE--CGKAFSRSSYLIEHQRIHTRAQW 608

Query: 556 ---------------------------------------------RTHSNEKPYICKIPG 570
                                                        R H+ EKPY C    
Sbjct: 609 FYEYGNALEGSTFVSRKKVNTIKKLHQCEDCEKIFRWRSHLIIHQRIHTGEKPYKCN--D 666

Query: 571 CTKRYTDPSSLRKHVK 586
           C K +   S L +H K
Sbjct: 667 CGKAFNRSSRLTQHQK 682



 Score = 48.1 bits (113), Expect = 7e-05
 Identities = 23/64 (35%), Positives = 35/64 (54%), Gaps = 2/64 (3%)

Query: 466 EKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLR 525
           +K   + +   C   +K F+ +  L++H R HTGEKP+KC    C KA++R   L  H +
Sbjct: 625 KKVNTIKKLHQCEDCEKIFRWRSHLIIHQRIHTGEKPYKC--NDCGKAFNRSSRLTQHQK 682

Query: 526 SHTG 529
            H G
Sbjct: 683 IHMG 686


>gi|117956407 zinc finger protein 568 [Homo sapiens]
          Length = 644

 Score =  104 bits (260), Expect = 6e-22
 Identities = 75/223 (33%), Positives = 103/223 (46%), Gaps = 19/223 (8%)

Query: 444 CTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPH 503
           C K +      + H+ +   H  +K +VC     +   K F     L VHMR HT EKP+
Sbjct: 395 CGKAFSQCSVFIIHMRS---HTGEKPYVC-----SECGKAFSQSSSLTVHMRNHTAEKPY 446

Query: 504 KCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 563
           +C  + C KA+SR ENL TH + HTGEKPY C    C KAF   S+  +HQ R H+ EKP
Sbjct: 447 EC--KECGKAFSRKENLITHQKIHTGEKPYECSE--CGKAFIQMSNLIRHQ-RIHTGEKP 501

Query: 564 YICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEAGTEPG 623
           Y C +  C K ++  S+L +H K +H  +      Q      +   L E+     G +P 
Sbjct: 502 YACTV--CGKAFSQKSNLTEHEK-IHTGEKPYHCNQCGKAFSQRQNLLEHEKIHTGEKPF 558

Query: 624 GPESTEASSTSQAVED-CLHVRAIKTESSGLCQSSPGAQSSCS 665
             +  E       +    LHVR+   E    C     A S CS
Sbjct: 559 --KCNECGKAFSRISSLTLHVRSHTGEKPYECNKCGKAFSQCS 599



 Score =  101 bits (252), Expect = 5e-21
 Identities = 59/145 (40%), Positives = 78/145 (53%), Gaps = 15/145 (10%)

Query: 442 EDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEK 501
           ++C K +  ++ L+ H   E IH  +K + C    C R    F     + +HMR HTGEK
Sbjct: 337 KECGKSFSQKQNLIEH---EKIHTGEKPYACN--ECGRA---FSRMSSVTLHMRSHTGEK 388

Query: 502 PHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNE 561
           P+KC    C KA+S+      H+RSHTGEKPYVC    C KAFS +S    H  R H+ E
Sbjct: 389 PYKC--NKCGKAFSQCSVFIIHMRSHTGEKPYVCSE--CGKAFSQSSSLTVHM-RNHTAE 443

Query: 562 KPYICKIPGCTKRYTDPSSLRKHVK 586
           KPY CK   C K ++   +L  H K
Sbjct: 444 KPYECK--ECGKAFSRKENLITHQK 466



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 67/190 (35%), Positives = 95/190 (50%), Gaps = 11/190 (5%)

Query: 477 CTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCE 536
           C +  + F  ++ L+ H R H GEKP++C  + C KA+SR ENL TH + HTGEKPY C 
Sbjct: 224 CNQCGQDFSHKFDLIRHERIHAGEKPYEC--KECGKAFSRKENLITHQKIHTGEKPYKCN 281

Query: 537 HEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVT 596
              C KAF   S+  +H +R H+ EKPY CK   C K ++  S+L +H +   G   +  
Sbjct: 282 E--CGKAFIQMSNLIRH-HRIHTGEKPYACK--DCWKAFSQKSNLIEHERIHTGEKPYEC 336

Query: 597 KKQRNDVHLRTPLLKENGDSEAGTEP-GGPESTEASSTSQAVEDCLHVRAIKTESSGLCQ 655
           K+       +  L+ E+     G +P    E   A S   +V   LH+R+   E    C 
Sbjct: 337 KECGKSFSQKQNLI-EHEKIHTGEKPYACNECGRAFSRMSSV--TLHMRSHTGEKPYKCN 393

Query: 656 SSPGAQSSCS 665
               A S CS
Sbjct: 394 KCGKAFSQCS 403



 Score = 92.4 bits (228), Expect = 3e-18
 Identities = 59/151 (39%), Positives = 78/151 (51%), Gaps = 16/151 (10%)

Query: 444 CTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPH 503
           C K +  +  L  H   E IH  +K +      C +  K F  +  L+ H + HTGEKP 
Sbjct: 507 CGKAFSQKSNLTEH---EKIHTGEKPY-----HCNQCGKAFSQRQNLLEHEKIHTGEKPF 558

Query: 504 KCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 563
           KC    C KA+SR+ +L  H+RSHTGEKPY C    C KAFS  S    H  R+H+ EKP
Sbjct: 559 KCN--ECGKAFSRISSLTLHVRSHTGEKPYECNK--CGKAFSQCSLLIIHM-RSHTGEKP 613

Query: 564 YICKIPGCTKRYTDPSSLRKHVKTVHGPDAH 594
           + C    C K ++  +SL  H K  H  + H
Sbjct: 614 FECN--ECGKAFSQRASLSIH-KRGHTGERH 641



 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 57/172 (33%), Positives = 81/172 (47%), Gaps = 43/172 (25%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCR--WQACTREQKPFKAQYMLVVHMRRHTGE 500
           +C K +     L+ H     IH  +K + C+  W+A       F  +  L+ H R HTGE
Sbjct: 282 ECGKAFIQMSNLIRH---HRIHTGEKPYACKDCWKA-------FSQKSNLIEHERIHTGE 331

Query: 501 KPHKCTFEG--------------------------CSKAYSRLENLKTHLRSHTGEKPYV 534
           KP++C   G                          C +A+SR+ ++  H+RSHTGEKPY 
Sbjct: 332 KPYECKECGKSFSQKQNLIEHEKIHTGEKPYACNECGRAFSRMSSVTLHMRSHTGEKPYK 391

Query: 535 CEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVK 586
           C    C KAFS  S    H  R+H+ EKPY+C    C K ++  SSL  H++
Sbjct: 392 CNK--CGKAFSQCSVFIIHM-RSHTGEKPYVCS--ECGKAFSQSSSLTVHMR 438



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 37/118 (31%), Positives = 52/118 (44%), Gaps = 28/118 (23%)

Query: 440 HWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVC-----------------------RWQA 476
           H   C K +  ++ L+ H   E IH  +K F C                       +   
Sbjct: 531 HCNQCGKAFSQRQNLLEH---EKIHTGEKPFKCNECGKAFSRISSLTLHVRSHTGEKPYE 587

Query: 477 CTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYV 534
           C +  K F    +L++HMR HTGEKP +C    C KA+S+  +L  H R HTGE+  V
Sbjct: 588 CNKCGKAFSQCSLLIIHMRSHTGEKPFECN--ECGKAFSQRASLSIHKRGHTGERHQV 643


>gi|10863995 zinc finger protein 410 [Homo sapiens]
          Length = 478

 Score =  103 bits (258), Expect = 1e-21
 Identities = 54/151 (35%), Positives = 76/151 (50%), Gaps = 9/151 (5%)

Query: 439 CHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHT 498
           C  E C + +       +H+     H   + F+C  + C    K F     L VHMR H 
Sbjct: 221 CTVEGCDRTFVWPAHFKYHLKT---HRNDRSFICPAEGCG---KSFYVLQRLKVHMRTHN 274

Query: 499 GEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTH 558
           GEKP  C   GC K ++   NLK H R HTGEKP++CE +GC ++F+  S   KH    H
Sbjct: 275 GEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAEYSSLRKHL-VVH 333

Query: 559 SNEKPYICKIPGCTKRYTDPSSLRKHVKTVH 589
           S EKP+ C++  C K ++   S   H++  H
Sbjct: 334 SGEKPHQCQV--CGKTFSQSGSRNVHMRKHH 362



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 69/246 (28%), Positives = 111/246 (45%), Gaps = 35/246 (14%)

Query: 467 KKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRS 526
           +K+  C  + C R    F        H++ H  ++   C  EGC K++  L+ LK H+R+
Sbjct: 216 EKKLKCTVEGCDRT---FVWPAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRT 272

Query: 527 HTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVK 586
           H GEKP++C   GC K F+ A +   H+ R H+ EKP++C+  GC + + + SSLRKH+ 
Sbjct: 273 HNGEKPFMCHESGCGKQFTTAGNLKNHR-RIHTGEKPFLCEAQGCGRSFAEYSSLRKHLV 331

Query: 587 TVHGPDAH--------VTKKQRNDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQAVE 638
              G   H         ++    +VH+R   L          + G   S E   T++ + 
Sbjct: 332 VHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHL----------QLGAAGSQEQEQTAEPLM 381

Query: 639 DCLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSA---PNNDS--GVEMPGTGPGSLGD 693
               +      S  L         S +S+PS  G +   PN +S  GV+      GS   
Sbjct: 382 GSSLLEEASVPSKNLV--------SMNSQPSLGGESLNLPNTNSILGVDDEVLAEGSPRS 433

Query: 694 LTALDD 699
           L+++ D
Sbjct: 434 LSSVPD 439


>gi|65507714 Wilms tumor 1 isoform A [Homo sapiens]
          Length = 497

 Score =  103 bits (257), Expect = 1e-21
 Identities = 49/119 (41%), Positives = 71/119 (59%), Gaps = 6/119 (5%)

Query: 466 EKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLR 525
           EK+ F+C +  C +    FK  + L +H R+HTGEKP++C F+ C + +SR + LK H R
Sbjct: 370 EKRPFMCAYPGCNKRY--FKLSH-LQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQR 426

Query: 526 SHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKH 584
            HTG KP+ C  + C + FS  SD  K   RTH+ EKP+ C+ P C K++     L +H
Sbjct: 427 RHTGVKPFQC--KTCQRKFSR-SDHLKTHTRTHTGEKPFSCRWPSCQKKFARSDELVRH 482



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 105/438 (23%), Positives = 158/438 (36%), Gaps = 58/438 (13%)

Query: 139 LSMISAARGLSPADVAQEHLKERGLFGLPAPGTTPSDYYHQMTLVAGHPAPYGDLLMQSG 198
           L +  AA+     D A       G  G PAP   P             P P+  +  +  
Sbjct: 94  LPVSGAAQWAPVLDFAPPGASAYGSLGGPAPPPAPPP--------PPPPPPHSFIKQEPS 145

Query: 199 GAASAPHLHDYLNPVDVSRFSSPRVTPRLSRKRALSISPLSDASLDLQRMIRTSP----- 253
              + PH    L+   V        T    R       P S AS    RM   +P     
Sbjct: 146 WGGAEPHEEQCLSAFTVHFSGQFTGTAGACRYGPFGPPPPSQASSGQARMFPNAPYLPSC 205

Query: 254 -NSLVAYINNSRSSSAASG--SYGHLSA--GALSPAFTFPHPINPVAYQQILSQQRGLGS 308
             S  A  N   S+    G  SYGH  +   A  P  +F H       +  + QQ  LG 
Sbjct: 206 LESQPAIRNQGYSTVTFDGTPSYGHTPSHHAAQFPNHSFKH-------EDPMGQQGSLGE 258

Query: 309 AFGHTPPLIQ----PSPTFLAQQPMALTSINATPT--QLSSSSNCLSDTNQNKQSSESAV 362
                PP +     P+ +    Q + L +  ++    Q++S   C++    N       +
Sbjct: 259 QQYSVPPPVYGCHTPTDSCTGSQALLLRTPYSSDNLYQMTSQLECMTWNQMN-------L 311

Query: 363 SSTVNPVAIHKRSKVKTEPEGLRPASPLALTQGQVSGHGSCGCALPLSQEQLADLKEDLD 422
            +T+   +    S   T P        L   Q ++  HG       +   ++  +   L 
Sbjct: 312 GATLKGHSTGYESDNHTTPI-------LCGAQYRIHTHGVFRGIQDV--RRVPGVAPTLV 362

Query: 423 RDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQK 482
           R   +   +       C +  C K Y     L  H      H  +K + C ++ C R   
Sbjct: 363 RSASETSEKRPFM---CAYPGCNKRYFKLSHLQMHSRK---HTGEKPYQCDFKDCERR-- 414

Query: 483 PFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNK 542
            F     L  H RRHTG KP +C  + C + +SR ++LKTH R+HTGEKP+ C    C K
Sbjct: 415 -FSRSDQLKRHQRRHTGVKPFQC--KTCQRKFSRSDHLKTHTRTHTGEKPFSCRWPSCQK 471

Query: 543 AFSNASDRAKHQNRTHSN 560
            F+ + +  +H N    N
Sbjct: 472 KFARSDELVRHHNMHQRN 489



 Score = 80.9 bits (198), Expect = 9e-15
 Identities = 39/101 (38%), Positives = 57/101 (56%), Gaps = 4/101 (3%)

Query: 491 VVHMRRHTGEK-PHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASD 549
           +V     T EK P  C + GC+K Y +L +L+ H R HTGEKPY C+ + C + FS  SD
Sbjct: 361 LVRSASETSEKRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSR-SD 419

Query: 550 RAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHG 590
           + K   R H+  KP+ CK   C ++++    L+ H +T  G
Sbjct: 420 QLKRHQRRHTGVKPFQCKT--CQRKFSRSDHLKTHTRTHTG 458


>gi|209180475 nuclear matrix transcription factor 4 isoform d [Homo
           sapiens]
          Length = 577

 Score =  103 bits (257), Expect = 1e-21
 Identities = 76/269 (28%), Positives = 118/269 (43%), Gaps = 25/269 (9%)

Query: 444 CTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPH 503
           C K +    QL H   +  IH +      +   C    K F     L  H+R H+G KP+
Sbjct: 289 CEKSF---RQLSHLQQHTRIHSKMHTETIKPHKCPHCSKTFANTSYLAQHLRIHSGAKPY 345

Query: 504 KCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 563
            C++  C KA+ +L +L+ H R HTG++PY C H GC KAF+  S+   H+ R H+ +KP
Sbjct: 346 NCSY--CQKAFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHR-RQHNKDKP 402

Query: 564 YICKIPGCTKRYTDPSSLRKHVKTVHGPDAHV------TKKQRNDVHLRTPLLKENGDS- 616
           + C    C + YTD +SL  H+ T     A V      ++   ++ +L   + K N    
Sbjct: 403 FKCH--NCHRAYTDAASLEVHLSTHTVKHAKVYTCTICSRAYTSETYLMKHMRKHNPPDL 460

Query: 617 ----EAGTEPGGPESTEASSTSQA-VEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSP- 670
               +A          +A + +QA  +     +A  +++S   Q     Q     +P P 
Sbjct: 461 QQQVQAAAAAAAVAQAQAQAQAQAQAQAQAQAQAQASQASQQQQQQQQQQQQQQQQPPPH 520

Query: 671 ---LGSAPNNDSGVEM-PGTGPGSLGDLT 695
               G+AP    G +  P   P    DLT
Sbjct: 521 FQSPGAAPQGGGGGDSNPNPPPQCSFDLT 549



 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 43/128 (33%), Positives = 63/128 (49%), Gaps = 17/128 (13%)

Query: 468 KEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSH 527
           K + CR  + T     F ++  + +H + HT  KPHKC    CSK ++    L  H+R H
Sbjct: 226 KTYRCRMCSLT-----FYSKSEMQIHSKSHTETKPHKCPH--CSKTFANSSYLAQHIRIH 278

Query: 528 TGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNE-----KPYICKIPGCTKRYTDPSSLR 582
           +G KPY C    C K+F   S   +H  R HS       KP+ C  P C+K + + S L 
Sbjct: 279 SGAKPYSCNF--CEKSFRQLSHLQQH-TRIHSKMHTETIKPHKC--PHCSKTFANTSYLA 333

Query: 583 KHVKTVHG 590
           +H++   G
Sbjct: 334 QHLRIHSG 341


>gi|239747149 PREDICTED: hypothetical protein XP_002343926 isoform 2
           [Homo sapiens]
          Length = 738

 Score =  102 bits (255), Expect = 2e-21
 Identities = 58/153 (37%), Positives = 84/153 (54%), Gaps = 15/153 (9%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           DC K +  + +L+ H   + IH  +K +      C+  +K F+ +  L+ H R HTGEKP
Sbjct: 379 DCRKAFFEKSELIRH---QTIHTGEKPY-----ECSECRKAFRERSSLINHQRTHTGEKP 430

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
           H C    C KA+S+  +L +H  +HTGEKP++C    C KAFS  S   +HQ RTH+ EK
Sbjct: 431 HGCI--QCGKAFSQKSHLISHQMTHTGEKPFICSK--CGKAFSRKSQLVRHQ-RTHTGEK 485

Query: 563 PYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHV 595
           PY C    C K +++  SL  H +   G   +V
Sbjct: 486 PYECS--ECGKAFSEKLSLTNHQRIHTGEKPYV 516



 Score =  100 bits (250), Expect = 9e-21
 Identities = 60/168 (35%), Positives = 88/168 (52%), Gaps = 15/168 (8%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           +C K +  +  L +H   + IH  +K +VC     +   K F  +  L+ H R HTGEKP
Sbjct: 491 ECGKAFSEKLSLTNH---QRIHTGEKPYVC-----SECGKAFCQKSHLISHQRTHTGEKP 542

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
           ++C+   C KA+    +L TH R+HTGEKPY C    C KAFS  S    HQ R H+ EK
Sbjct: 543 YECS--ECGKAFGEKSSLATHQRTHTGEKPYEC--RDCEKAFSQKSQLNTHQ-RIHTGEK 597

Query: 563 PYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLL 610
           PY C +  C K + + S L +H++T  G   +   + R     ++ L+
Sbjct: 598 PYECSL--CRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLI 643



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 60/155 (38%), Positives = 78/155 (50%), Gaps = 21/155 (13%)

Query: 444 CTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPH 503
           C K +  + +L+ H+      GEK         C   +K F+ +  L+ H R HTGEKP 
Sbjct: 604 CRKAFFEKSELIRHLRTHT--GEKP------YECNECRKAFREKSSLINHQRIHTGEKPF 655

Query: 504 KCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 563
           +C+   C KA+SR  +L  H R+HTGEKPY C    C KAFS  S    HQ R H+ EKP
Sbjct: 656 ECS--ECGKAFSRKSHLIPHQRTHTGEKPYGCSE--CRKAFSQKSQLVNHQ-RIHTGEKP 710

Query: 564 YICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKK 598
           Y C    C K ++  S L  H +T      H  KK
Sbjct: 711 YRC--IECGKAFSQKSQLINHQRT------HTVKK 737



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 62/190 (32%), Positives = 93/190 (48%), Gaps = 35/190 (18%)

Query: 428 QEAEVVIYETNCHWE------DCTKEYDTQEQLVHHINNEHIHG-------------EKK 468
           ++++++IY  N   E      +C K +  +  L+ H  + HI               +K 
Sbjct: 190 KKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKH-QSRHIRDIAFGCGNCGKTFPQKS 248

Query: 469 EFVCRWQACTREQ--------KPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENL 520
           +F+   +  T E+        K F  +  L  H R HTGEKP++C    C KA+SR  +L
Sbjct: 249 QFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECG--ECGKAFSRKSHL 306

Query: 521 KTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSS 580
            +H R+HTGEKPY C    C +AFS  S+   HQ R H+ EKP+ C+   C K ++  S 
Sbjct: 307 ISHWRTHTGEKPYGCNE--CGRAFSEKSNLINHQ-RIHTGEKPFECR--ECGKAFSRKSQ 361

Query: 581 LRKHVKTVHG 590
           L  H +T  G
Sbjct: 362 LVTHHRTHTG 371



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 55/142 (38%), Positives = 73/142 (51%), Gaps = 15/142 (10%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           +C K +  +  L+ H   +  H  +K +      C+   K F  +  L  H R HTGEKP
Sbjct: 519 ECGKAFCQKSHLISH---QRTHTGEKPY-----ECSECGKAFGEKSSLATHQRTHTGEKP 570

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
           ++C    C KA+S+   L TH R HTGEKPY C    C KAF   S+  +H  RTH+ EK
Sbjct: 571 YEC--RDCEKAFSQKSQLNTHQRIHTGEKPYECSL--CRKAFFEKSELIRHL-RTHTGEK 625

Query: 563 PYICKIPGCTKRYTDPSSLRKH 584
           PY C    C K + + SSL  H
Sbjct: 626 PYECN--ECRKAFREKSSLINH 645



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 57/152 (37%), Positives = 75/152 (49%), Gaps = 15/152 (9%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           +C K +  +  L+ H      H  +K + C    C R    F  +  L+ H R HTGEKP
Sbjct: 295 ECGKAFSRKSHLISHWRT---HTGEKPYGCN--ECGRA---FSEKSNLINHQRIHTGEKP 346

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
            +C    C KA+SR   L TH R+HTG KP+ C    C KAF   S+  +HQ   H+ EK
Sbjct: 347 FEC--RECGKAFSRKSQLVTHHRTHTGTKPFGC--SDCRKAFFEKSELIRHQT-IHTGEK 401

Query: 563 PYICKIPGCTKRYTDPSSLRKHVKTVHGPDAH 594
           PY C    C K + + SSL  H +T  G   H
Sbjct: 402 PYECS--ECRKAFRERSSLINHQRTHTGEKPH 431


>gi|239747147 PREDICTED: hypothetical protein XP_002343925 isoform 1
           [Homo sapiens]
          Length = 738

 Score =  102 bits (255), Expect = 2e-21
 Identities = 58/153 (37%), Positives = 84/153 (54%), Gaps = 15/153 (9%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           DC K +  + +L+ H   + IH  +K +      C+  +K F+ +  L+ H R HTGEKP
Sbjct: 379 DCRKAFFEKSELIRH---QTIHTGEKPY-----ECSECRKAFRERSSLINHQRTHTGEKP 430

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
           H C    C KA+S+  +L +H  +HTGEKP++C    C KAFS  S   +HQ RTH+ EK
Sbjct: 431 HGCI--QCGKAFSQKSHLISHQMTHTGEKPFICSK--CGKAFSRKSQLVRHQ-RTHTGEK 485

Query: 563 PYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHV 595
           PY C    C K +++  SL  H +   G   +V
Sbjct: 486 PYECS--ECGKAFSEKLSLTNHQRIHTGEKPYV 516



 Score =  100 bits (250), Expect = 9e-21
 Identities = 60/168 (35%), Positives = 88/168 (52%), Gaps = 15/168 (8%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           +C K +  +  L +H   + IH  +K +VC     +   K F  +  L+ H R HTGEKP
Sbjct: 491 ECGKAFSEKLSLTNH---QRIHTGEKPYVC-----SECGKAFCQKSHLISHQRTHTGEKP 542

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
           ++C+   C KA+    +L TH R+HTGEKPY C    C KAFS  S    HQ R H+ EK
Sbjct: 543 YECS--ECGKAFGEKSSLATHQRTHTGEKPYEC--RDCEKAFSQKSQLNTHQ-RIHTGEK 597

Query: 563 PYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLL 610
           PY C +  C K + + S L +H++T  G   +   + R     ++ L+
Sbjct: 598 PYECSL--CRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLI 643



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 60/155 (38%), Positives = 78/155 (50%), Gaps = 21/155 (13%)

Query: 444 CTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPH 503
           C K +  + +L+ H+      GEK         C   +K F+ +  L+ H R HTGEKP 
Sbjct: 604 CRKAFFEKSELIRHLRTHT--GEKP------YECNECRKAFREKSSLINHQRIHTGEKPF 655

Query: 504 KCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 563
           +C+   C KA+SR  +L  H R+HTGEKPY C    C KAFS  S    HQ R H+ EKP
Sbjct: 656 ECS--ECGKAFSRKSHLIPHQRTHTGEKPYGCSE--CRKAFSQKSQLVNHQ-RIHTGEKP 710

Query: 564 YICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKK 598
           Y C    C K ++  S L  H +T      H  KK
Sbjct: 711 YRC--IECGKAFSQKSQLINHQRT------HTVKK 737



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 62/190 (32%), Positives = 93/190 (48%), Gaps = 35/190 (18%)

Query: 428 QEAEVVIYETNCHWE------DCTKEYDTQEQLVHHINNEHIHG-------------EKK 468
           ++++++IY  N   E      +C K +  +  L+ H  + HI               +K 
Sbjct: 190 KKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKH-QSRHIRDIAFGCGNCGKTFPQKS 248

Query: 469 EFVCRWQACTREQ--------KPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENL 520
           +F+   +  T E+        K F  +  L  H R HTGEKP++C    C KA+SR  +L
Sbjct: 249 QFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECG--ECGKAFSRKSHL 306

Query: 521 KTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSS 580
            +H R+HTGEKPY C    C +AFS  S+   HQ R H+ EKP+ C+   C K ++  S 
Sbjct: 307 ISHWRTHTGEKPYGCNE--CGRAFSEKSNLINHQ-RIHTGEKPFECR--ECGKAFSRKSQ 361

Query: 581 LRKHVKTVHG 590
           L  H +T  G
Sbjct: 362 LVTHHRTHTG 371



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 55/142 (38%), Positives = 73/142 (51%), Gaps = 15/142 (10%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           +C K +  +  L+ H   +  H  +K +      C+   K F  +  L  H R HTGEKP
Sbjct: 519 ECGKAFCQKSHLISH---QRTHTGEKPY-----ECSECGKAFGEKSSLATHQRTHTGEKP 570

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
           ++C    C KA+S+   L TH R HTGEKPY C    C KAF   S+  +H  RTH+ EK
Sbjct: 571 YEC--RDCEKAFSQKSQLNTHQRIHTGEKPYECSL--CRKAFFEKSELIRHL-RTHTGEK 625

Query: 563 PYICKIPGCTKRYTDPSSLRKH 584
           PY C    C K + + SSL  H
Sbjct: 626 PYECN--ECRKAFREKSSLINH 645



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 57/152 (37%), Positives = 75/152 (49%), Gaps = 15/152 (9%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           +C K +  +  L+ H      H  +K + C    C R    F  +  L+ H R HTGEKP
Sbjct: 295 ECGKAFSRKSHLISHWRT---HTGEKPYGCN--ECGRA---FSEKSNLINHQRIHTGEKP 346

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
            +C    C KA+SR   L TH R+HTG KP+ C    C KAF   S+  +HQ   H+ EK
Sbjct: 347 FEC--RECGKAFSRKSQLVTHHRTHTGTKPFGC--SDCRKAFFEKSELIRHQT-IHTGEK 401

Query: 563 PYICKIPGCTKRYTDPSSLRKHVKTVHGPDAH 594
           PY C    C K + + SSL  H +T  G   H
Sbjct: 402 PYECS--ECRKAFRERSSLINHQRTHTGEKPH 431


>gi|239747145 PREDICTED: hypothetical protein XP_002343927 isoform 3
           [Homo sapiens]
          Length = 738

 Score =  102 bits (255), Expect = 2e-21
 Identities = 58/153 (37%), Positives = 84/153 (54%), Gaps = 15/153 (9%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           DC K +  + +L+ H   + IH  +K +      C+  +K F+ +  L+ H R HTGEKP
Sbjct: 379 DCRKAFFEKSELIRH---QTIHTGEKPY-----ECSECRKAFRERSSLINHQRTHTGEKP 430

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
           H C    C KA+S+  +L +H  +HTGEKP++C    C KAFS  S   +HQ RTH+ EK
Sbjct: 431 HGCI--QCGKAFSQKSHLISHQMTHTGEKPFICSK--CGKAFSRKSQLVRHQ-RTHTGEK 485

Query: 563 PYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHV 595
           PY C    C K +++  SL  H +   G   +V
Sbjct: 486 PYECS--ECGKAFSEKLSLTNHQRIHTGEKPYV 516



 Score =  100 bits (250), Expect = 9e-21
 Identities = 60/168 (35%), Positives = 88/168 (52%), Gaps = 15/168 (8%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           +C K +  +  L +H   + IH  +K +VC     +   K F  +  L+ H R HTGEKP
Sbjct: 491 ECGKAFSEKLSLTNH---QRIHTGEKPYVC-----SECGKAFCQKSHLISHQRTHTGEKP 542

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
           ++C+   C KA+    +L TH R+HTGEKPY C    C KAFS  S    HQ R H+ EK
Sbjct: 543 YECS--ECGKAFGEKSSLATHQRTHTGEKPYEC--RDCEKAFSQKSQLNTHQ-RIHTGEK 597

Query: 563 PYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLL 610
           PY C +  C K + + S L +H++T  G   +   + R     ++ L+
Sbjct: 598 PYECSL--CRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLI 643



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 60/155 (38%), Positives = 78/155 (50%), Gaps = 21/155 (13%)

Query: 444 CTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPH 503
           C K +  + +L+ H+      GEK         C   +K F+ +  L+ H R HTGEKP 
Sbjct: 604 CRKAFFEKSELIRHLRTHT--GEKP------YECNECRKAFREKSSLINHQRIHTGEKPF 655

Query: 504 KCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 563
           +C+   C KA+SR  +L  H R+HTGEKPY C    C KAFS  S    HQ R H+ EKP
Sbjct: 656 ECS--ECGKAFSRKSHLIPHQRTHTGEKPYGCSE--CRKAFSQKSQLVNHQ-RIHTGEKP 710

Query: 564 YICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKK 598
           Y C    C K ++  S L  H +T      H  KK
Sbjct: 711 YRC--IECGKAFSQKSQLINHQRT------HTVKK 737



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 62/190 (32%), Positives = 93/190 (48%), Gaps = 35/190 (18%)

Query: 428 QEAEVVIYETNCHWE------DCTKEYDTQEQLVHHINNEHIHG-------------EKK 468
           ++++++IY  N   E      +C K +  +  L+ H  + HI               +K 
Sbjct: 190 KKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKH-QSRHIRDIAFGCGNCGKTFPQKS 248

Query: 469 EFVCRWQACTREQ--------KPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENL 520
           +F+   +  T E+        K F  +  L  H R HTGEKP++C    C KA+SR  +L
Sbjct: 249 QFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECG--ECGKAFSRKSHL 306

Query: 521 KTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSS 580
            +H R+HTGEKPY C    C +AFS  S+   HQ R H+ EKP+ C+   C K ++  S 
Sbjct: 307 ISHWRTHTGEKPYGCNE--CGRAFSEKSNLINHQ-RIHTGEKPFECR--ECGKAFSRKSQ 361

Query: 581 LRKHVKTVHG 590
           L  H +T  G
Sbjct: 362 LVTHHRTHTG 371



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 55/142 (38%), Positives = 73/142 (51%), Gaps = 15/142 (10%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           +C K +  +  L+ H   +  H  +K +      C+   K F  +  L  H R HTGEKP
Sbjct: 519 ECGKAFCQKSHLISH---QRTHTGEKPY-----ECSECGKAFGEKSSLATHQRTHTGEKP 570

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
           ++C    C KA+S+   L TH R HTGEKPY C    C KAF   S+  +H  RTH+ EK
Sbjct: 571 YEC--RDCEKAFSQKSQLNTHQRIHTGEKPYECSL--CRKAFFEKSELIRHL-RTHTGEK 625

Query: 563 PYICKIPGCTKRYTDPSSLRKH 584
           PY C    C K + + SSL  H
Sbjct: 626 PYECN--ECRKAFREKSSLINH 645



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 57/152 (37%), Positives = 75/152 (49%), Gaps = 15/152 (9%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           +C K +  +  L+ H      H  +K + C    C R    F  +  L+ H R HTGEKP
Sbjct: 295 ECGKAFSRKSHLISHWRT---HTGEKPYGCN--ECGRA---FSEKSNLINHQRIHTGEKP 346

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
            +C    C KA+SR   L TH R+HTG KP+ C    C KAF   S+  +HQ   H+ EK
Sbjct: 347 FEC--RECGKAFSRKSQLVTHHRTHTGTKPFGC--SDCRKAFFEKSELIRHQT-IHTGEK 401

Query: 563 PYICKIPGCTKRYTDPSSLRKHVKTVHGPDAH 594
           PY C    C K + + SSL  H +T  G   H
Sbjct: 402 PYECS--ECRKAFRERSSLINHQRTHTGEKPH 431


>gi|55769561 zinc finger protein 21 isoform 2 [Homo sapiens]
          Length = 620

 Score =  102 bits (255), Expect = 2e-21
 Identities = 64/160 (40%), Positives = 84/160 (52%), Gaps = 19/160 (11%)

Query: 435 YETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHM 494
           YE N    +C K +  +  L+ H   +  H E+K + C    C    K F+ +  L++H 
Sbjct: 467 YECN----ECEKAFSQKSYLIIH---QRTHTEEKPYKCN--ECG---KAFREKSKLIIHQ 514

Query: 495 RRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQ 554
           R HTGEKP++C    C KA+S+   L  H R+HTGEKPY C    C KAF   S    HQ
Sbjct: 515 RIHTGEKPYECPV--CWKAFSQKSQLIIHQRTHTGEKPYACTE--CGKAFREKSTFTVHQ 570

Query: 555 NRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAH 594
            RTH+ EKPY C    C K +T  S+L  H +T  G  AH
Sbjct: 571 -RTHTGEKPYKC--TECGKAFTQKSNLIVHQRTHAGKKAH 607



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 58/160 (36%), Positives = 84/160 (52%), Gaps = 15/160 (9%)

Query: 428 QEAEVVIYETNCHWE---DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPF 484
           Q++ +++++     E   +CTK  ++  Q +  I +   H  KK        C   +K F
Sbjct: 310 QKSNLIVHQKTHTGEKTYECTKCGESFIQKLDLIIHHSTHTGKKP-----HECNECKKTF 364

Query: 485 KAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAF 544
             +  L++H R HTGEKPHKCT   C K+++    L  H R+HTGEKPY C  + C K F
Sbjct: 365 SDKSTLIIHQRTHTGEKPHKCT--ECGKSFNEKSTLIVHQRTHTGEKPYEC--DVCGKTF 420

Query: 545 SNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKH 584
           +  S+   HQ RTHS EKP+ C    C K ++  S L  H
Sbjct: 421 TQKSNLGVHQ-RTHSGEKPFECN--ECEKAFSQKSYLMLH 457



 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 62/158 (39%), Positives = 81/158 (51%), Gaps = 15/158 (9%)

Query: 441 WEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGE 500
           +++C K    ++ L  H   + I   +K F C   AC   +K F  +  L+VH R HTGE
Sbjct: 189 YKECGKGLRRKKGLSLH---QRIKNGEKPFECT--AC---RKTFSKKSHLIVHWRTHTGE 240

Query: 501 KPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSN 560
           KP  CT   C KA+S+   L  HLR+HTGE+P+ C    C KAF   S    H  RTH+ 
Sbjct: 241 KPFGCT--ECGKAFSQKSQLIIHLRTHTGERPFECPE--CGKAFREKSTVIIHY-RTHTG 295

Query: 561 EKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKK 598
           EKPY C    C K +T  S+L  H KT  G   +   K
Sbjct: 296 EKPYECN--ECGKAFTQKSNLIVHQKTHTGEKTYECTK 331



 Score = 87.8 bits (216), Expect = 8e-17
 Identities = 56/142 (39%), Positives = 72/142 (50%), Gaps = 15/142 (10%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           +C K ++ +  L+ H   +  H  +K + C    C    K F  +  L VH R H+GEKP
Sbjct: 387 ECGKSFNEKSTLIVH---QRTHTGEKPYEC--DVCG---KTFTQKSNLGVHQRTHSGEKP 438

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
            +C    C KA+S+   L  H R HTGEKPY C    C KAFS  S    HQ RTH+ EK
Sbjct: 439 FECN--ECEKAFSQKSYLMLHQRGHTGEKPYECNE--CEKAFSQKSYLIIHQ-RTHTEEK 493

Query: 563 PYICKIPGCTKRYTDPSSLRKH 584
           PY C    C K + + S L  H
Sbjct: 494 PYKCN--ECGKAFREKSKLIIH 513


>gi|55769559 zinc finger protein 21 isoform 1 [Homo sapiens]
          Length = 639

 Score =  102 bits (255), Expect = 2e-21
 Identities = 64/160 (40%), Positives = 84/160 (52%), Gaps = 19/160 (11%)

Query: 435 YETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHM 494
           YE N    +C K +  +  L+ H   +  H E+K + C    C    K F+ +  L++H 
Sbjct: 486 YECN----ECEKAFSQKSYLIIH---QRTHTEEKPYKCN--ECG---KAFREKSKLIIHQ 533

Query: 495 RRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQ 554
           R HTGEKP++C    C KA+S+   L  H R+HTGEKPY C    C KAF   S    HQ
Sbjct: 534 RIHTGEKPYECPV--CWKAFSQKSQLIIHQRTHTGEKPYACTE--CGKAFREKSTFTVHQ 589

Query: 555 NRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAH 594
            RTH+ EKPY C    C K +T  S+L  H +T  G  AH
Sbjct: 590 -RTHTGEKPYKC--TECGKAFTQKSNLIVHQRTHAGKKAH 626



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 58/160 (36%), Positives = 84/160 (52%), Gaps = 15/160 (9%)

Query: 428 QEAEVVIYETNCHWE---DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPF 484
           Q++ +++++     E   +CTK  ++  Q +  I +   H  KK        C   +K F
Sbjct: 329 QKSNLIVHQKTHTGEKTYECTKCGESFIQKLDLIIHHSTHTGKKP-----HECNECKKTF 383

Query: 485 KAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAF 544
             +  L++H R HTGEKPHKCT   C K+++    L  H R+HTGEKPY C  + C K F
Sbjct: 384 SDKSTLIIHQRTHTGEKPHKCT--ECGKSFNEKSTLIVHQRTHTGEKPYEC--DVCGKTF 439

Query: 545 SNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKH 584
           +  S+   HQ RTHS EKP+ C    C K ++  S L  H
Sbjct: 440 TQKSNLGVHQ-RTHSGEKPFECN--ECEKAFSQKSYLMLH 476



 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 62/158 (39%), Positives = 81/158 (51%), Gaps = 15/158 (9%)

Query: 441 WEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGE 500
           +++C K    ++ L  H   + I   +K F C   AC   +K F  +  L+VH R HTGE
Sbjct: 208 YKECGKGLRRKKGLSLH---QRIKNGEKPFECT--AC---RKTFSKKSHLIVHWRTHTGE 259

Query: 501 KPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSN 560
           KP  CT   C KA+S+   L  HLR+HTGE+P+ C    C KAF   S    H  RTH+ 
Sbjct: 260 KPFGCT--ECGKAFSQKSQLIIHLRTHTGERPFECPE--CGKAFREKSTVIIHY-RTHTG 314

Query: 561 EKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKK 598
           EKPY C    C K +T  S+L  H KT  G   +   K
Sbjct: 315 EKPYECN--ECGKAFTQKSNLIVHQKTHTGEKTYECTK 350



 Score = 87.8 bits (216), Expect = 8e-17
 Identities = 56/142 (39%), Positives = 72/142 (50%), Gaps = 15/142 (10%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           +C K ++ +  L+ H   +  H  +K + C    C    K F  +  L VH R H+GEKP
Sbjct: 406 ECGKSFNEKSTLIVH---QRTHTGEKPYEC--DVCG---KTFTQKSNLGVHQRTHSGEKP 457

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
            +C    C KA+S+   L  H R HTGEKPY C    C KAFS  S    HQ RTH+ EK
Sbjct: 458 FECN--ECEKAFSQKSYLMLHQRGHTGEKPYECNE--CEKAFSQKSYLIIHQ-RTHTEEK 512

Query: 563 PYICKIPGCTKRYTDPSSLRKH 584
           PY C    C K + + S L  H
Sbjct: 513 PYKCN--ECGKAFREKSKLIIH 532


>gi|188497655 zinc finger protein 84 [Homo sapiens]
          Length = 738

 Score =  102 bits (255), Expect = 2e-21
 Identities = 58/153 (37%), Positives = 84/153 (54%), Gaps = 15/153 (9%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           DC K +  + +L+ H   + IH  +K +      C+  +K F+ +  L+ H R HTGEKP
Sbjct: 379 DCRKAFFEKSELIRH---QTIHTGEKPY-----ECSECRKAFRERSSLINHQRTHTGEKP 430

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
           H C    C KA+S+  +L +H  +HTGEKP++C    C KAFS  S   +HQ RTH+ EK
Sbjct: 431 HGCI--QCGKAFSQKSHLISHQMTHTGEKPFICSK--CGKAFSRKSQLVRHQ-RTHTGEK 485

Query: 563 PYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHV 595
           PY C    C K +++  SL  H +   G   +V
Sbjct: 486 PYECS--ECGKAFSEKLSLTNHQRIHTGEKPYV 516



 Score =  100 bits (250), Expect = 9e-21
 Identities = 60/168 (35%), Positives = 88/168 (52%), Gaps = 15/168 (8%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           +C K +  +  L +H   + IH  +K +VC     +   K F  +  L+ H R HTGEKP
Sbjct: 491 ECGKAFSEKLSLTNH---QRIHTGEKPYVC-----SECGKAFCQKSHLISHQRTHTGEKP 542

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
           ++C+   C KA+    +L TH R+HTGEKPY C    C KAFS  S    HQ R H+ EK
Sbjct: 543 YECS--ECGKAFGEKSSLATHQRTHTGEKPYEC--RDCEKAFSQKSQLNTHQ-RIHTGEK 597

Query: 563 PYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLL 610
           PY C +  C K + + S L +H++T  G   +   + R     ++ L+
Sbjct: 598 PYECSL--CRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLI 643



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 60/155 (38%), Positives = 78/155 (50%), Gaps = 21/155 (13%)

Query: 444 CTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPH 503
           C K +  + +L+ H+      GEK         C   +K F+ +  L+ H R HTGEKP 
Sbjct: 604 CRKAFFEKSELIRHLRTHT--GEKP------YECNECRKAFREKSSLINHQRIHTGEKPF 655

Query: 504 KCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 563
           +C+   C KA+SR  +L  H R+HTGEKPY C    C KAFS  S    HQ R H+ EKP
Sbjct: 656 ECS--ECGKAFSRKSHLIPHQRTHTGEKPYGCSE--CRKAFSQKSQLVNHQ-RIHTGEKP 710

Query: 564 YICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKK 598
           Y C    C K ++  S L  H +T      H  KK
Sbjct: 711 YRC--IECGKAFSQKSQLINHQRT------HTVKK 737



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 62/190 (32%), Positives = 93/190 (48%), Gaps = 35/190 (18%)

Query: 428 QEAEVVIYETNCHWE------DCTKEYDTQEQLVHHINNEHIHG-------------EKK 468
           ++++++IY  N   E      +C K +  +  L+ H  + HI               +K 
Sbjct: 190 KKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKH-QSRHIRDIAFGCGNCGKTFPQKS 248

Query: 469 EFVCRWQACTREQ--------KPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENL 520
           +F+   +  T E+        K F  +  L  H R HTGEKP++C    C KA+SR  +L
Sbjct: 249 QFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECG--ECGKAFSRKSHL 306

Query: 521 KTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSS 580
            +H R+HTGEKPY C    C +AFS  S+   HQ R H+ EKP+ C+   C K ++  S 
Sbjct: 307 ISHWRTHTGEKPYGCNE--CGRAFSEKSNLINHQ-RIHTGEKPFECR--ECGKAFSRKSQ 361

Query: 581 LRKHVKTVHG 590
           L  H +T  G
Sbjct: 362 LVTHHRTHTG 371



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 55/142 (38%), Positives = 73/142 (51%), Gaps = 15/142 (10%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           +C K +  +  L+ H   +  H  +K +      C+   K F  +  L  H R HTGEKP
Sbjct: 519 ECGKAFCQKSHLISH---QRTHTGEKPY-----ECSECGKAFGEKSSLATHQRTHTGEKP 570

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
           ++C    C KA+S+   L TH R HTGEKPY C    C KAF   S+  +H  RTH+ EK
Sbjct: 571 YEC--RDCEKAFSQKSQLNTHQRIHTGEKPYECSL--CRKAFFEKSELIRHL-RTHTGEK 625

Query: 563 PYICKIPGCTKRYTDPSSLRKH 584
           PY C    C K + + SSL  H
Sbjct: 626 PYECN--ECRKAFREKSSLINH 645



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 57/152 (37%), Positives = 75/152 (49%), Gaps = 15/152 (9%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           +C K +  +  L+ H      H  +K + C    C R    F  +  L+ H R HTGEKP
Sbjct: 295 ECGKAFSRKSHLISHWRT---HTGEKPYGCN--ECGRA---FSEKSNLINHQRIHTGEKP 346

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
            +C    C KA+SR   L TH R+HTG KP+ C    C KAF   S+  +HQ   H+ EK
Sbjct: 347 FEC--RECGKAFSRKSQLVTHHRTHTGTKPFGC--SDCRKAFFEKSELIRHQT-IHTGEK 401

Query: 563 PYICKIPGCTKRYTDPSSLRKHVKTVHGPDAH 594
           PY C    C K + + SSL  H +T  G   H
Sbjct: 402 PYECS--ECRKAFRERSSLINHQRTHTGEKPH 431


>gi|188497653 zinc finger protein 84 [Homo sapiens]
          Length = 738

 Score =  102 bits (255), Expect = 2e-21
 Identities = 58/153 (37%), Positives = 84/153 (54%), Gaps = 15/153 (9%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           DC K +  + +L+ H   + IH  +K +      C+  +K F+ +  L+ H R HTGEKP
Sbjct: 379 DCRKAFFEKSELIRH---QTIHTGEKPY-----ECSECRKAFRERSSLINHQRTHTGEKP 430

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
           H C    C KA+S+  +L +H  +HTGEKP++C    C KAFS  S   +HQ RTH+ EK
Sbjct: 431 HGCI--QCGKAFSQKSHLISHQMTHTGEKPFICSK--CGKAFSRKSQLVRHQ-RTHTGEK 485

Query: 563 PYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHV 595
           PY C    C K +++  SL  H +   G   +V
Sbjct: 486 PYECS--ECGKAFSEKLSLTNHQRIHTGEKPYV 516



 Score =  100 bits (250), Expect = 9e-21
 Identities = 60/168 (35%), Positives = 88/168 (52%), Gaps = 15/168 (8%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           +C K +  +  L +H   + IH  +K +VC     +   K F  +  L+ H R HTGEKP
Sbjct: 491 ECGKAFSEKLSLTNH---QRIHTGEKPYVC-----SECGKAFCQKSHLISHQRTHTGEKP 542

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
           ++C+   C KA+    +L TH R+HTGEKPY C    C KAFS  S    HQ R H+ EK
Sbjct: 543 YECS--ECGKAFGEKSSLATHQRTHTGEKPYEC--RDCEKAFSQKSQLNTHQ-RIHTGEK 597

Query: 563 PYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLL 610
           PY C +  C K + + S L +H++T  G   +   + R     ++ L+
Sbjct: 598 PYECSL--CRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLI 643



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 60/155 (38%), Positives = 78/155 (50%), Gaps = 21/155 (13%)

Query: 444 CTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPH 503
           C K +  + +L+ H+      GEK         C   +K F+ +  L+ H R HTGEKP 
Sbjct: 604 CRKAFFEKSELIRHLRTHT--GEKP------YECNECRKAFREKSSLINHQRIHTGEKPF 655

Query: 504 KCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKP 563
           +C+   C KA+SR  +L  H R+HTGEKPY C    C KAFS  S    HQ R H+ EKP
Sbjct: 656 ECS--ECGKAFSRKSHLIPHQRTHTGEKPYGCSE--CRKAFSQKSQLVNHQ-RIHTGEKP 710

Query: 564 YICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKK 598
           Y C    C K ++  S L  H +T      H  KK
Sbjct: 711 YRC--IECGKAFSQKSQLINHQRT------HTVKK 737



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 62/190 (32%), Positives = 93/190 (48%), Gaps = 35/190 (18%)

Query: 428 QEAEVVIYETNCHWE------DCTKEYDTQEQLVHHINNEHIHG-------------EKK 468
           ++++++IY  N   E      +C K +  +  L+ H  + HI               +K 
Sbjct: 190 KKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKH-QSRHIRDIAFGCGNCGKTFPQKS 248

Query: 469 EFVCRWQACTREQ--------KPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENL 520
           +F+   +  T E+        K F  +  L  H R HTGEKP++C    C KA+SR  +L
Sbjct: 249 QFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECG--ECGKAFSRKSHL 306

Query: 521 KTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSS 580
            +H R+HTGEKPY C    C +AFS  S+   HQ R H+ EKP+ C+   C K ++  S 
Sbjct: 307 ISHWRTHTGEKPYGCNE--CGRAFSEKSNLINHQ-RIHTGEKPFECR--ECGKAFSRKSQ 361

Query: 581 LRKHVKTVHG 590
           L  H +T  G
Sbjct: 362 LVTHHRTHTG 371



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 55/142 (38%), Positives = 73/142 (51%), Gaps = 15/142 (10%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           +C K +  +  L+ H   +  H  +K +      C+   K F  +  L  H R HTGEKP
Sbjct: 519 ECGKAFCQKSHLISH---QRTHTGEKPY-----ECSECGKAFGEKSSLATHQRTHTGEKP 570

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
           ++C    C KA+S+   L TH R HTGEKPY C    C KAF   S+  +H  RTH+ EK
Sbjct: 571 YEC--RDCEKAFSQKSQLNTHQRIHTGEKPYECSL--CRKAFFEKSELIRHL-RTHTGEK 625

Query: 563 PYICKIPGCTKRYTDPSSLRKH 584
           PY C    C K + + SSL  H
Sbjct: 626 PYECN--ECRKAFREKSSLINH 645



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 57/152 (37%), Positives = 75/152 (49%), Gaps = 15/152 (9%)

Query: 443 DCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKP 502
           +C K +  +  L+ H      H  +K + C    C R    F  +  L+ H R HTGEKP
Sbjct: 295 ECGKAFSRKSHLISHWRT---HTGEKPYGCN--ECGRA---FSEKSNLINHQRIHTGEKP 346

Query: 503 HKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEK 562
            +C    C KA+SR   L TH R+HTG KP+ C    C KAF   S+  +HQ   H+ EK
Sbjct: 347 FEC--RECGKAFSRKSQLVTHHRTHTGTKPFGC--SDCRKAFFEKSELIRHQT-IHTGEK 401

Query: 563 PYICKIPGCTKRYTDPSSLRKHVKTVHGPDAH 594
           PY C    C K + + SSL  H +T  G   H
Sbjct: 402 PYECS--ECRKAFRERSSLINHQRTHTGEKPH 431


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,903,864
Number of Sequences: 37866
Number of extensions: 4774672
Number of successful extensions: 43452
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 975
Number of HSP's successfully gapped in prelim test: 652
Number of HSP's that attempted gapping in prelim test: 16097
Number of HSP's gapped (non-prelim): 9207
length of query: 1586
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1470
effective length of database: 13,855,062
effective search space: 20366941140
effective search space used: 20366941140
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.