Search of human proteins with 83977444

Search of human proteins with 83977444

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|83977444 5-aminolevulinate synthase 2 isoform c precursor
[Homo sapiens]
         (574 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|83977444 5-aminolevulinate synthase 2 isoform c precursor [Ho...  1173   0.0  
gi|83977440 5-aminolevulinate synthase 2 isoform b precursor [Ho...  1121   0.0  
gi|83977442 5-aminolevulinate synthase 2 isoform a precursor [Ho...  1103   0.0  
gi|40316939 5-aminolevulinate synthase 1 [Homo sapiens]               687   0.0  
gi|4502025 5-aminolevulinate synthase 1 [Homo sapiens]                687   0.0  
gi|7657118 glycine C-acetyltransferase precursor [Homo sapiens]       223   3e-58
gi|119220554 serine palmitoyltransferase, long chain base subuni...   172   6e-43
gi|4758668 serine palmitoyltransferase, long chain base subunit ...   154   2e-37
gi|5454084 serine palmitoyltransferase subunit 1 isoform a [Homo...   123   5e-28
gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform...    31   2.7  
gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform ...    31   2.7  
gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform ...    31   2.7  
gi|66529005 ATP-binding cassette, sub-family C, member 5 isoform...    31   3.5  
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    31   3.5  
gi|30474871 serine palmitoyltransferase subunit 1 isoform b [Hom...    30   6.0  
gi|41872631 fatty acid synthase [Homo sapiens]                         30   7.9  
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             30   7.9  

>gi|83977444 5-aminolevulinate synthase 2 isoform c precursor [Homo
           sapiens]
          Length = 574

 Score = 1173 bits (3034), Expect = 0.0
 Identities = 574/574 (100%), Positives = 574/574 (100%)

Query: 1   MRGGEVALGWNKKKRLFCEDFRFKMVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIG 60
           MRGGEVALGWNKKKRLFCEDFRFKMVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIG
Sbjct: 1   MRGGEVALGWNKKKRLFCEDFRFKMVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIG 60

Query: 61  RCPILATQGPNCSQIHLKATKAGGDSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDV 120
           RCPILATQGPNCSQIHLKATKAGGDSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDV
Sbjct: 61  RCPILATQGPNCSQIHLKATKAGGDSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDV 120

Query: 121 KAFKTGNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQHFSEASVASKDVSV 180
           KAFKTGNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQHFSEASVASKDVSV
Sbjct: 121 KAFKTGNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQHFSEASVASKDVSV 180

Query: 181 WCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSAL 240
           WCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSAL
Sbjct: 181 WCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSAL 240

Query: 241 LFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKL 300
           LFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKL
Sbjct: 241 LFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKL 300

Query: 301 LEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIG 360
           LEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIG
Sbjct: 301 LEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIG 360

Query: 361 ERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALE 420
           ERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALE
Sbjct: 361 ERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALE 420

Query: 421 SVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDLL 480
           SVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDLL
Sbjct: 421 SVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDLL 480

Query: 481 LSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAWTAVGLPLQDVSVA 540
           LSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAWTAVGLPLQDVSVA
Sbjct: 481 LSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAWTAVGLPLQDVSVA 540

Query: 541 ACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA 574
           ACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA
Sbjct: 541 ACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA 574


>gi|83977440 5-aminolevulinate synthase 2 isoform b precursor [Homo
           sapiens]
          Length = 550

 Score = 1121 bits (2900), Expect = 0.0
 Identities = 550/550 (100%), Positives = 550/550 (100%)

Query: 25  MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQGPNCSQIHLKATKAGG 84
           MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQGPNCSQIHLKATKAGG
Sbjct: 1   MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQGPNCSQIHLKATKAGG 60

Query: 85  DSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKTGNYVFSYDQFFRDKIMEKK 144
           DSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKTGNYVFSYDQFFRDKIMEKK
Sbjct: 61  DSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKTGNYVFSYDQFFRDKIMEKK 120

Query: 145 QDHTYRVFKTVNRWADAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQ 204
           QDHTYRVFKTVNRWADAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQ
Sbjct: 121 QDHTYRVFKTVNRWADAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQ 180

Query: 205 RHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCE 264
           RHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCE
Sbjct: 181 RHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCE 240

Query: 265 IYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAI 324
           IYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAI
Sbjct: 241 IYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAI 300

Query: 325 CPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVG 384
           CPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVG
Sbjct: 301 CPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVG 360

Query: 385 GYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHM 444
           GYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHM
Sbjct: 361 GYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHM 420

Query: 445 RQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLR 504
           RQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLR
Sbjct: 421 RQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLR 480

Query: 505 LAPSPHHSPQMMEDFVEKLLLAWTAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGN 564
           LAPSPHHSPQMMEDFVEKLLLAWTAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGN
Sbjct: 481 LAPSPHHSPQMMEDFVEKLLLAWTAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGN 540

Query: 565 MGPQYVTTYA 574
           MGPQYVTTYA
Sbjct: 541 MGPQYVTTYA 550


>gi|83977442 5-aminolevulinate synthase 2 isoform a precursor [Homo
           sapiens]
          Length = 587

 Score = 1103 bits (2852), Expect = 0.0
 Identities = 550/587 (93%), Positives = 550/587 (93%), Gaps = 37/587 (6%)

Query: 25  MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQGPNCSQIHLKATKAGG 84
           MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQGPNCSQIHLKATKAGG
Sbjct: 1   MVTAAMLLQCCPVLARGPTSLLGKVVKTHQFLFGIGRCPILATQGPNCSQIHLKATKAGG 60

Query: 85  DSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKT------------------- 125
           DSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKT                   
Sbjct: 61  DSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKTDLPSSLVSVSLRKPFSGPQ 120

Query: 126 ------------------GNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQH 167
                             GNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQH
Sbjct: 121 EQEQISGKVTHLIQNNMPGNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQH 180

Query: 168 FSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELE 227
           FSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELE
Sbjct: 181 FSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELE 240

Query: 228 QELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKF 287
           QELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKF
Sbjct: 241 QELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKF 300

Query: 288 VFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVH 347
           VFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVH
Sbjct: 301 VFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVH 360

Query: 348 AVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFT 407
           AVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFT
Sbjct: 361 AVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFT 420

Query: 408 TSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRV 467
           TSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRV
Sbjct: 421 TSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRV 480

Query: 468 GNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAW 527
           GNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAW
Sbjct: 481 GNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAW 540

Query: 528 TAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA 574
           TAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA
Sbjct: 541 TAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA 587


>gi|40316939 5-aminolevulinate synthase 1 [Homo sapiens]
          Length = 640

 Score =  687 bits (1773), Expect = 0.0
 Identities = 332/483 (68%), Positives = 395/483 (81%), Gaps = 10/483 (2%)

Query: 83  GGDSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKTGNYVFSYDQFFRDKIME 142
           GGD     K     M  +  +  S ++Q   P      K+  T    F YD+FF  KI E
Sbjct: 160 GGDPSGLLKNFQDIMQKQRPERVSHLLQDNLP------KSVST----FQYDRFFEKKIDE 209

Query: 143 KKQDHTYRVFKTVNRWADAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQET 202
           KK DHTYRVFKTVNR A  +P A  +S++ +  K VSVWCSNDYLGMSRHP+V  A  +T
Sbjct: 210 KKNDHTYRVFKTVNRRAHIFPMADDYSDSLITKKQVSVWCSNDYLGMSRHPRVCGAVMDT 269

Query: 203 LQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILPG 262
           L++HGAGAGGTRNISGTSKFHV+LE+ELA+LH KD+ALLFSSCFVANDSTLFTLAK++PG
Sbjct: 270 LKQHGAGAGGTRNISGTSKFHVDLERELADLHGKDAALLFSSCFVANDSTLFTLAKMMPG 329

Query: 263 CEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDG 322
           CEIYSD+GNHASMIQGIRNS   K++FRHND  HL++LL++S+P +PKIVAFETVHSMDG
Sbjct: 330 CEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVSHLRELLQRSDPSVPKIVAFETVHSMDG 389

Query: 323 AICPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGC 382
           A+CPLEELCDV+H++GA+TFVDEVHAVGLYG+RG GIG+RDG+M K+DIISGTLGKAFGC
Sbjct: 390 AVCPLEELCDVAHEFGAITFVDEVHAVGLYGARGGGIGDRDGVMPKMDIISGTLGKAFGC 449

Query: 383 VGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVK 442
           VGGYIAST  L+D VRSYAAGFIFTTSLPPM+L+GALESVR+LK  EG+ LRR HQRNVK
Sbjct: 450 VGGYIASTSSLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSAEGRVLRRQHQRNVK 509

Query: 443 HMRQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEEL 502
            MRQ+LMD GLPV+ CPSHIIP+RV +AA N+++CD L+S+H IYVQAINYPTVPRGEEL
Sbjct: 510 LMRQMLMDAGLPVVHCPSHIIPVRVADAAKNTEVCDELMSRHNIYVQAINYPTVPRGEEL 569

Query: 503 LRLAPSPHHSPQMMEDFVEKLLLAWTAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYF 562
           LR+AP+PHH+PQMM  F+E LL+ W  VGL L+  S A CNFCRRP+HFE+MSE E+SYF
Sbjct: 570 LRIAPTPHHTPQMMNYFLENLLVTWKQVGLELKPHSSAECNFCRRPLHFEVMSEREKSYF 629

Query: 563 GNM 565
             +
Sbjct: 630 SGL 632


>gi|4502025 5-aminolevulinate synthase 1 [Homo sapiens]
          Length = 640

 Score =  687 bits (1773), Expect = 0.0
 Identities = 332/483 (68%), Positives = 395/483 (81%), Gaps = 10/483 (2%)

Query: 83  GGDSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKTGNYVFSYDQFFRDKIME 142
           GGD     K     M  +  +  S ++Q   P      K+  T    F YD+FF  KI E
Sbjct: 160 GGDPSGLLKNFQDIMQKQRPERVSHLLQDNLP------KSVST----FQYDRFFEKKIDE 209

Query: 143 KKQDHTYRVFKTVNRWADAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQET 202
           KK DHTYRVFKTVNR A  +P A  +S++ +  K VSVWCSNDYLGMSRHP+V  A  +T
Sbjct: 210 KKNDHTYRVFKTVNRRAHIFPMADDYSDSLITKKQVSVWCSNDYLGMSRHPRVCGAVMDT 269

Query: 203 LQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILPG 262
           L++HGAGAGGTRNISGTSKFHV+LE+ELA+LH KD+ALLFSSCFVANDSTLFTLAK++PG
Sbjct: 270 LKQHGAGAGGTRNISGTSKFHVDLERELADLHGKDAALLFSSCFVANDSTLFTLAKMMPG 329

Query: 263 CEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDG 322
           CEIYSD+GNHASMIQGIRNS   K++FRHND  HL++LL++S+P +PKIVAFETVHSMDG
Sbjct: 330 CEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVSHLRELLQRSDPSVPKIVAFETVHSMDG 389

Query: 323 AICPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGC 382
           A+CPLEELCDV+H++GA+TFVDEVHAVGLYG+RG GIG+RDG+M K+DIISGTLGKAFGC
Sbjct: 390 AVCPLEELCDVAHEFGAITFVDEVHAVGLYGARGGGIGDRDGVMPKMDIISGTLGKAFGC 449

Query: 383 VGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVK 442
           VGGYIAST  L+D VRSYAAGFIFTTSLPPM+L+GALESVR+LK  EG+ LRR HQRNVK
Sbjct: 450 VGGYIASTSSLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSAEGRVLRRQHQRNVK 509

Query: 443 HMRQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEEL 502
            MRQ+LMD GLPV+ CPSHIIP+RV +AA N+++CD L+S+H IYVQAINYPTVPRGEEL
Sbjct: 510 LMRQMLMDAGLPVVHCPSHIIPVRVADAAKNTEVCDELMSRHNIYVQAINYPTVPRGEEL 569

Query: 503 LRLAPSPHHSPQMMEDFVEKLLLAWTAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYF 562
           LR+AP+PHH+PQMM  F+E LL+ W  VGL L+  S A CNFCRRP+HFE+MSE E+SYF
Sbjct: 570 LRIAPTPHHTPQMMNYFLENLLVTWKQVGLELKPHSSAECNFCRRPLHFEVMSEREKSYF 629

Query: 563 GNM 565
             +
Sbjct: 630 SGL 632


>gi|7657118 glycine C-acetyltransferase precursor [Homo sapiens]
          Length = 419

 Score =  223 bits (569), Expect = 3e-58
 Identities = 131/352 (37%), Positives = 202/352 (57%), Gaps = 10/352 (2%)

Query: 181 WCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSAL 240
           +C+N+YLG+S HP+V+QA  + L+  GAG    R I GT   H  LE ++A  HQ++ A+
Sbjct: 70  FCANNYLGLSSHPEVIQAGLQALEEFGAGLSSVRFICGTQSIHKNLEAKIARFHQREDAI 129

Query: 241 LFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKL 300
           L+ SC+ AN + LF  A + P   + SD  NHAS+I GIR   A K+ +RH D   L+  
Sbjct: 130 LYPSCYDAN-AGLFE-ALLTPEDAVLSDELNHASIIDGIRLCKAHKYRYRHLDMADLEAK 187

Query: 301 LEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIG 360
           L+++     ++VA +   SMDG I PL+E+C ++ +YGAL F+DE HA G  G  G G  
Sbjct: 188 LQEAQKHRLRLVATDGAFSMDGDIAPLQEICCLASRYGALVFMDECHATGFLGPTGRGTD 247

Query: 361 ERDGIMHKIDIISGTLGKAF-GCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGAL 419
           E  G+M ++ II+ TLGKA  G  GGY      LV ++R  A  ++F+ SLPP V+  A 
Sbjct: 248 ELLGVMDQVTIINSTLGKALGGASGGYTTGPGPLVSLLRQRARPYLFSNSLPPAVVGCAS 307

Query: 420 ESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDL 479
           +++ LL G     + ++     +  R  +   G  +      I P+ +G+A L S++ D 
Sbjct: 308 KALDLLMG--SNTIVQSMAAKTQRFRSKMEAAGFTISGASHPICPVMLGDARLASRMADD 365

Query: 480 LLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAWTAVG 531
           +L K GI+V   +YP VP+G+  +R+  S  HS    E+ +++ + A+  VG
Sbjct: 366 ML-KRGIFVIGFSYPVVPKGKARIRVQISAVHS----EEDIDRCVEAFVEVG 412


>gi|119220554 serine palmitoyltransferase, long chain base subunit 3
           [Homo sapiens]
          Length = 552

 Score =  172 bits (437), Expect = 6e-43
 Identities = 113/389 (29%), Positives = 204/389 (52%), Gaps = 21/389 (5%)

Query: 151 VFKTVNRWADAYPFAQHFSEASVASKDVSVWCSNDYLGMS-RHPQVLQATQETLQRHGAG 209
           +F  + R +D Y +   F+   +  KDV    S ++LG++ ++ + ++  ++ L+ +G G
Sbjct: 137 LFDLMERVSDDYNWTFRFTGRVI--KDVINMGSYNFLGLAAKYDESMRTIKDVLEVYGTG 194

Query: 210 AGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDA 269
              TR+  GT   H ELE  +A+    ++A++F   F  N   +  L  +  GC I SD 
Sbjct: 195 VASTRHEMGTLDKHKELEDLVAKFLNVEAAMVFGMGFATNSMNIPAL--VGKGCLILSDE 252

Query: 270 GNHASMIQGIRNSGAAKFVFRHNDPDHLKKLLEKS----NPKIPK-----IVAFETVHSM 320
            NH S++ G R SGA   +F+HN+   L+KLL  +     P+  +     ++  E V+SM
Sbjct: 253 LNHTSLVLGARLSGATIRIFKHNNTQSLEKLLRDAVIYGQPRTRRAWKKILILVEGVYSM 312

Query: 321 DGAICPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGI-MHKIDIISGTLGKA 379
           +G+I  L ++  +  +Y A  ++DE H++G  G  G G+ E  G+  H++D++ GT  K+
Sbjct: 313 EGSIVHLPQIIALKKKYKAYLYIDEAHSIGAVGPTGRGVTEFFGLDPHEVDVLMGTFTKS 372

Query: 380 FGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEG--QALRRAH 437
           FG  GGYIA  +DLVD +R ++   ++ +S+ P +    + S++L+ G +G  Q L+R  
Sbjct: 373 FGASGGYIAGRKDLVDYLRVHSHSAVYASSMSPPIAEQIIRSLKLIMGLDGTTQGLQRVQ 432

Query: 438 Q--RNVKHMRQLLMDRGLPVIPCP-SHIIPIRVGNAALNSKLCDLLLSKHGIYVQAINYP 494
           Q  +N ++ RQ L + G  +     + ++P+ +      +     +L K  I V  + +P
Sbjct: 433 QLAKNTRYFRQRLQEMGFIIYGNENASVVPLLLYMPGKVAAFARHMLEKK-IGVVVVGFP 491

Query: 495 TVPRGEELLRLAPSPHHSPQMMEDFVEKL 523
             P  E   R   S  H+ +M++  +E L
Sbjct: 492 ATPLAEARARFCVSAAHTREMLDTVLEAL 520


>gi|4758668 serine palmitoyltransferase, long chain base subunit 2
           [Homo sapiens]
          Length = 562

 Score =  154 bits (390), Expect = 2e-37
 Identities = 103/364 (28%), Positives = 183/364 (50%), Gaps = 33/364 (9%)

Query: 183 SNDYLGMSRHPQVLQ-ATQETLQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALL 241
           S +YLG +R+    Q A  + L+ +GAG   TR   G    H ELE+ +A     ++A+ 
Sbjct: 175 SYNYLGFARNTGSCQEAAAKVLEEYGAGVCSTRQEIGNLDKHEELEELVARFLGVEAAMA 234

Query: 242 FSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLL 301
           +   F  N   +  L  +  GC I SD  NHAS++ G R SGA   +F+HN+   L+KLL
Sbjct: 235 YGMGFATNSMNIPAL--VGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLL 292

Query: 302 EKS---------NPKIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVHAVGLY 352
           + +          P    ++  E ++SM+G+I  L E+  +  +Y A  ++DE H++G  
Sbjct: 293 KDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGAL 352

Query: 353 GSRGAGIGERDGI-MHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLP 411
           G  G G+ E  G+    +D++ GT  K+FG  GGYI   ++L+D +R+++   ++ TSL 
Sbjct: 353 GPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSLS 412

Query: 412 PMVLSGALESVRLLKGEEGQALRR----AHQRNVKHMRQLLMDRGL--------PVIPCP 459
           P V+   + S++ + G++G +L +        N ++ R+ L + G         PV+P  
Sbjct: 413 PPVVEQIITSMKCIMGQDGTSLGKECVQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLM 472

Query: 460 SHIIPIRVGNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDF 519
            + +P ++G            + K  I V  + +P  P  E   R   S  H+ ++++  
Sbjct: 473 LY-MPAKIGAFGRE-------MLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTA 524

Query: 520 VEKL 523
           ++++
Sbjct: 525 LKEI 528


>gi|5454084 serine palmitoyltransferase subunit 1 isoform a [Homo
           sapiens]
          Length = 473

 Score =  123 bits (308), Expect = 5e-28
 Identities = 75/269 (27%), Positives = 142/269 (52%), Gaps = 13/269 (4%)

Query: 173 VASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELEQELAE 232
           V  K+   + S ++LG+  +P+V  A   +L+++G G  G R   GT   H++LE  LA+
Sbjct: 95  VNGKECINFASFNFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAK 154

Query: 233 LHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHN 292
             + + A+++S  F    S +   +K   G  ++ D     ++ +G++ S +   +F+HN
Sbjct: 155 FMKTEEAIIYSYGFATIASAIPAYSK--RGDIVFVDRAACFAIQKGLQASRSDIKLFKHN 212

Query: 293 DPDHLKKLL------EKSNPKIPKI----VAFETVHSMDGAICPLEELCDVSHQYGALTF 342
           D   L++LL      ++ NP+  ++    +  E ++   G ICPL EL  + ++Y A  F
Sbjct: 213 DMADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPLPELVKLKYKYKARIF 272

Query: 343 VDEVHAVGLYGSRGAGIGERDGI-MHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYA 401
           ++E  + G+ G  G G+ E  GI +  ID+IS  +  A   +GG+      ++D  R   
Sbjct: 273 LEESLSFGVLGEHGRGVTEHYGINIDDIDLISANMENALASIGGFCCGRSFVIDHQRLSG 332

Query: 402 AGFIFTTSLPPMVLSGALESVRLLKGEEG 430
            G+ F+ SLPP++ + A+E++ +++   G
Sbjct: 333 QGYCFSASLPPLLAAAAIEALNIMEENPG 361


>gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform c
           precursor [Homo sapiens]
          Length = 899

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 235 QKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDP 294
           Q+D+A  F+S  +   S +  +   +P        G   S  Q    +G++     +N+ 
Sbjct: 767 QQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSST----NNNE 822

Query: 295 DHLKKLLEKSNPKIPKIVA 313
           +   +LLEK N ++ KI+A
Sbjct: 823 EEKSRLLEKENRELEKIIA 841


>gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform b
           precursor [Homo sapiens]
          Length = 844

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 235 QKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDP 294
           Q+D+A  F+S  +   S +  +   +P        G   S  Q    +G++     +N+ 
Sbjct: 712 QQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSST----NNNE 767

Query: 295 DHLKKLLEKSNPKIPKIVA 313
           +   +LLEK N ++ KI+A
Sbjct: 768 EEKSRLLEKENRELEKIIA 786


>gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform a
           precursor [Homo sapiens]
          Length = 961

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 235 QKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDP 294
           Q+D+A  F+S  +   S +  +   +P        G   S  Q    +G++     +N+ 
Sbjct: 829 QQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSST----NNNE 884

Query: 295 DHLKKLLEKSNPKIPKIVA 313
           +   +LLEK N ++ KI+A
Sbjct: 885 EEKSRLLEKENRELEKIIA 903


>gi|66529005 ATP-binding cassette, sub-family C, member 5 isoform 1
           [Homo sapiens]
          Length = 1437

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 18/62 (29%), Positives = 28/62 (45%)

Query: 427 GEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDLLLSKHGI 486
           GE G  L    ++ +   R L  DR + ++  P   +   VGN   NS +   L SK  +
Sbjct: 679 GERGANLSGGQRQRISLARALYSDRSIYILDDPLSALDAHVGNHIFNSAIRKHLKSKTVL 738

Query: 487 YV 488
           +V
Sbjct: 739 FV 740


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin
           (with transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 33/142 (23%), Positives = 58/142 (40%), Gaps = 18/142 (12%)

Query: 99  SELQDGKSKIVQKAAPEVQEDVKAF----KTGNYVFSYDQFFRD---KIMEKKQDHTYRV 151
           +EL+   S + QK   E++E         KTG  + S     +D   K+++ K +   + 
Sbjct: 357 AELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQS 416

Query: 152 FKTVNRWADAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAG 211
            +T+ +  D         +    SK++S + +   L + +H    Q +   +   G  A 
Sbjct: 417 AQTIQQLED---------QLQQKSKEISQFLNR--LPLQQHETASQTSFPDVYNEGTQAV 465

Query: 212 GTRNISGTSKFHVELEQELAEL 233
              NI+   K  VELE E   L
Sbjct: 466 TEENIASLQKRVVELENEKGAL 487


>gi|30474871 serine palmitoyltransferase subunit 1 isoform b [Homo
           sapiens]
          Length = 143

 Score = 30.0 bits (66), Expect = 6.0
 Identities = 15/47 (31%), Positives = 26/47 (55%)

Query: 173 VASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGT 219
           V  K+   + S ++LG+  +P+V  A   +L+++G G  G R   GT
Sbjct: 95  VNGKECINFASFNFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGT 141


>gi|41872631 fatty acid synthase [Homo sapiens]
          Length = 2511

 Score = 29.6 bits (65), Expect = 7.9
 Identities = 12/26 (46%), Positives = 14/26 (53%)

Query: 186  YLGMSRHPQVLQATQETLQRHGAGAG 211
            Y    RHPQ L+A Q  LQ+H    G
Sbjct: 1270 YTATDRHPQALEAAQAELQQHDVAQG 1295


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 29.6 bits (65), Expect = 7.9
 Identities = 30/139 (21%), Positives = 60/139 (43%), Gaps = 20/139 (14%)

Query: 98  LSELQDGKSKIVQKAAPEVQEDVKAFKTGNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNR 157
           +S+L+   +K  Q+ A  VQE  K   + N +   +Q   + +++K+QD+T         
Sbjct: 269 ISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYT--------- 319

Query: 158 WADAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNIS 217
                   +  +E SV+ K++        L   +    L A++ +L R          +S
Sbjct: 320 -----KLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHV------ELS 368

Query: 218 GTSKFHVELEQELAELHQK 236
              +   +L++EL+E+  K
Sbjct: 369 EKGEATQKLKEELSEVETK 387


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,182,734
Number of Sequences: 37866
Number of extensions: 981883
Number of successful extensions: 2073
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2046
Number of HSP's gapped (non-prelim): 20
length of query: 574
length of database: 18,247,518
effective HSP length: 108
effective length of query: 466
effective length of database: 14,157,990
effective search space: 6597623340
effective search space used: 6597623340
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.