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Search of human proteins with 7706557
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7706557 chromosome 9 open reading frame 78 [Homo sapiens]
(289 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7706557 chromosome 9 open reading frame 78 [Homo sapiens] 575 e-164
gi|32130516 serologically defined colon cancer antigen 1 [Homo s... 41 0.001
gi|117414154 sodium channel associated protein 2 isoform b [Homo... 41 0.001
gi|117414162 sodium channel associated protein 2 isoform a [Homo... 41 0.001
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 39 0.005
gi|148746195 trichohyalin [Homo sapiens] 39 0.007
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 37 0.015
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 37 0.015
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 37 0.015
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 37 0.015
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 37 0.015
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 37 0.015
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 37 0.015
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 37 0.015
gi|45439327 periplakin [Homo sapiens] 37 0.020
gi|221219020 NYD-SP11 protein [Homo sapiens] 36 0.034
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 36 0.034
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 36 0.034
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 36 0.034
gi|155030242 WD repeat domain 60 [Homo sapiens] 36 0.034
gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens] 36 0.045
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 36 0.045
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 36 0.045
gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens] 35 0.059
gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens] 35 0.059
gi|4503249 DEK oncogene isoform 1 [Homo sapiens] 35 0.059
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 35 0.059
gi|167466187 integrin-binding sialoprotein precursor [Homo sapiens] 35 0.077
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 35 0.077
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 35 0.077
>gi|7706557 chromosome 9 open reading frame 78 [Homo sapiens]
Length = 289
Score = 575 bits (1482), Expect = e-164
Identities = 289/289 (100%), Positives = 289/289 (100%)
Query: 1 MPVVRKIFRRRRGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQE 60
MPVVRKIFRRRRGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQE
Sbjct: 1 MPVVRKIFRRRRGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQE 60
Query: 61 ETTLVDDPFQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIE 120
ETTLVDDPFQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIE
Sbjct: 61 ETTLVDDPFQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIE 120
Query: 121 TELKKRKGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGI 180
TELKKRKGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGI
Sbjct: 121 TELKKRKGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGI 180
Query: 181 DAKIKNIISTEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNK 240
DAKIKNIISTEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNK
Sbjct: 181 DAKIKNIISTEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNK 240
Query: 241 EEPKARPLRVGDTEKPEPERSPPNRKRPANEKATDDYHYEKFKKMNRRY 289
EEPKARPLRVGDTEKPEPERSPPNRKRPANEKATDDYHYEKFKKMNRRY
Sbjct: 241 EEPKARPLRVGDTEKPEPERSPPNRKRPANEKATDDYHYEKFKKMNRRY 289
>gi|32130516 serologically defined colon cancer antigen 1 [Homo
sapiens]
Length = 1076
Score = 40.8 bits (94), Expect = 0.001
Identities = 34/138 (24%), Positives = 63/138 (45%), Gaps = 22/138 (15%)
Query: 14 DSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQ--- 70
+S + D + L +E RE++ +K P+ + L G+ ++E+T+ + Q
Sbjct: 801 ESSNSSDSKSQSRRHLSAKERREMKK-KKLPSDSGDLEALEGKDKEKESTVHIETHQNTS 859
Query: 71 --------MKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETE 122
MK G MKK+KE+ KD+ E+ +L + SA +N+ ++
Sbjct: 860 KNVAAVQPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGK--------- 910
Query: 123 LKKRKGIVEHEEQKVKPK 140
K +KG + E K +P+
Sbjct: 911 -KGKKGKTKDEPVKKQPQ 927
>gi|117414154 sodium channel associated protein 2 isoform b [Homo
sapiens]
Length = 939
Score = 40.8 bits (94), Expect = 0.001
Identities = 46/241 (19%), Positives = 105/241 (43%), Gaps = 31/241 (12%)
Query: 11 RRGDSESEEDEQDSEEVRLKL----EETREVQNLR-----------KRPNGVSAVALLVG 55
R + + +E DS+ +R+K ++T ++ L+ + ++ +
Sbjct: 703 RENECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQ 762
Query: 56 EKVQEETTLVDDPFQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADM 115
E++ E+++ +D+ + +KLK++ K K E E++ ++S + + ++
Sbjct: 763 EQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIR--KAYSTLNRKWHDKGEL 820
Query: 116 MKYIETELKKRKGIVEHEEQKVK---------PKNAEDCLYELPENIR--VSSAKKTEEM 164
+ ++ET++K+ K E++E+K+K KNA + L+ + + + V + + +
Sbjct: 821 LCHLETQVKEVKEKFENKEKKLKAERDKSIELQKNAMEKLHSMDDAFKRQVDAIVEAHQA 880
Query: 165 LSNQMLSGIPEVDLGIDAKIKNIISTEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQH 224
Q+ + E ID+ + E LL E KK E A+N +Q
Sbjct: 881 EIAQLAN---EKQKCIDSANLKVHQIEKEMRELLEETCKNKKTMEAKIKQLAFALNEIQQ 937
Query: 225 N 225
+
Sbjct: 938 D 938
>gi|117414162 sodium channel associated protein 2 isoform a [Homo
sapiens]
Length = 1032
Score = 40.8 bits (94), Expect = 0.001
Identities = 46/241 (19%), Positives = 105/241 (43%), Gaps = 31/241 (12%)
Query: 11 RRGDSESEEDEQDSEEVRLKL----EETREVQNLR-----------KRPNGVSAVALLVG 55
R + + +E DS+ +R+K ++T ++ L+ + ++ +
Sbjct: 796 RENECLRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQ 855
Query: 56 EKVQEETTLVDDPFQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADM 115
E++ E+++ +D+ + +KLK++ K K E E++ ++S + + ++
Sbjct: 856 EQLDEKSSQLDEVLEKLERHNERKEKLKQQLKGKEVELEEIR--KAYSTLNRKWHDKGEL 913
Query: 116 MKYIETELKKRKGIVEHEEQKVK---------PKNAEDCLYELPENIR--VSSAKKTEEM 164
+ ++ET++K+ K E++E+K+K KNA + L+ + + + V + + +
Sbjct: 914 LCHLETQVKEVKEKFENKEKKLKAERDKSIELQKNAMEKLHSMDDAFKRQVDAIVEAHQA 973
Query: 165 LSNQMLSGIPEVDLGIDAKIKNIISTEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQH 224
Q+ + E ID+ + E LL E KK E A+N +Q
Sbjct: 974 EIAQLAN---EKQKCIDSANLKVHQIEKEMRELLEETCKNKKTMEAKIKQLAFALNEIQQ 1030
Query: 225 N 225
+
Sbjct: 1031 D 1031
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 38.9 bits (89), Expect = 0.005
Identities = 62/276 (22%), Positives = 111/276 (40%), Gaps = 20/276 (7%)
Query: 15 SESEEDEQDSEEVRL--KLEETREVQNLRKRPNGVSAVALLVGEKV---QEETTLVDDPF 69
S + D +D+EE + K +E E + ++ G + V ++V EK QEET ++
Sbjct: 171 SYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKN 230
Query: 70 QMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKR--- 126
+ ++ +E+G D+IS E + AE R +A+ + I+ E K+
Sbjct: 231 GQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIAD 290
Query: 127 -KGIVEHEE----QKVKPKNAEDCLYELPENIRVSSAK---KTEEMLSNQMLSGIPEVDL 178
+ +E EE Q+ + + AE+ E R + + K EE + + I E +
Sbjct: 291 ERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEK 350
Query: 179 GIDAKIKNIISTEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRR 238
A+ + I E+ +A AE++ + + E Q H I+
Sbjct: 351 RA-AEERQRIKEEEKRA---AEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKG 406
Query: 239 NKEEPKARPLRVGDTEKPEPERSPPNRKRPANEKAT 274
K E K V + + E + K+ EK T
Sbjct: 407 EKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGT 442
Score = 32.3 bits (72), Expect = 0.50
Identities = 17/38 (44%), Positives = 26/38 (68%), Gaps = 3/38 (7%)
Query: 9 RRRRGDSESEEDE---QDSEEVRLKLEETREVQNLRKR 43
RRRRG++ESEE E Q +E L+LEE ++ + R++
Sbjct: 540 RRRRGETESEEFEKLKQKQQEAALELEELKKKREERRK 577
Score = 28.1 bits (61), Expect = 9.4
Identities = 32/135 (23%), Positives = 56/135 (41%), Gaps = 27/135 (20%)
Query: 18 EEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQMKTGGMV 77
+++E E+++ E EV++ R G + V GE + + ++ F + GG
Sbjct: 459 KKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFS-RPGGRA 517
Query: 78 DMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKGIVEHEE-QK 136
+ + G ++ E +R E EL++R+G E EE +K
Sbjct: 518 SVDTKEAEGAPQV--------------EAGKRLE----------ELRRRRGETESEEFEK 553
Query: 137 VKPKNAEDCLYELPE 151
+K K E L EL E
Sbjct: 554 LKQKQQEAAL-ELEE 567
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 38.5 bits (88), Expect = 0.007
Identities = 55/283 (19%), Positives = 113/283 (39%), Gaps = 20/283 (7%)
Query: 9 RRRRGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDP 68
RR + +E+E+ +++R + EE R Q LR+ L ++++ E L +
Sbjct: 346 RREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQ 405
Query: 69 FQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETE----LK 124
+ + ++L+ + + +EE+ H E RR++ +K + E LK
Sbjct: 406 QLRREQQLRREQQLRREQQLRREQEEERH---EQKHEQERREQ---RLKREQEERRDWLK 459
Query: 125 KRKGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKI 184
+ + HE+++ K + D E E ++ E + E + + ++
Sbjct: 460 REEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRL 519
Query: 185 KNIISTEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKEEPK 244
K E + RL +EQQ +++ E + + R E ++R +EE +
Sbjct: 520 KRQEEEERLQQRLRSEQQLRREQEER----REQLLKREEEKRLEQERREQRLKREQEERR 575
Query: 245 ARPLRVGDTEKPEPERSPPNRKRPANEKATDDYHYEKFKKMNR 287
+ L K E ER KR E+ E+ +++ +
Sbjct: 576 DQLL------KREEERRQQRLKREQEERLEQRLKREEVERLEQ 612
Score = 33.9 bits (76), Expect = 0.17
Identities = 53/266 (19%), Positives = 101/266 (37%), Gaps = 21/266 (7%)
Query: 9 RRRRGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDP 68
RR+ + + E+EQ +E L E RE + ++R L + +EE L ++P
Sbjct: 922 RRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL---QQKEEQLLGEEP 978
Query: 69 FQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKG 128
+ ++ +ER K K EEE+L + R + + + E + +K+
Sbjct: 979 ---------EKRRRQEREK-KYREEEELQ---QEEEQLLREEREKRRRQEWERQYRKKDE 1025
Query: 129 IVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEV--DLGIDAKIKN 186
+ + EEQ ++ + + L E R + EE Q+L E ++ + +
Sbjct: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEE---EQLLGEERETRRRQELERQYRK 1082
Query: 187 IISTEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKEEPKAR 246
+ + +LL E+ K++ E + + EE R+ E
Sbjct: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYRE 1142
Query: 247 PLRVGDTEKPEPERSPPNRKRPANEK 272
V E+ P R+R E+
Sbjct: 1143 EEEVQQEEEQLLREEPEKRRRQELER 1168
Score = 32.3 bits (72), Expect = 0.50
Identities = 58/308 (18%), Positives = 124/308 (40%), Gaps = 57/308 (18%)
Query: 9 RRRRGDSESEED-----EQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETT 63
+R + + E D E++ + RLK E+ ++ KR V L E+ +E+
Sbjct: 565 QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREE----VERLEQEERREQRL 620
Query: 64 LVDDPFQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETEL 123
++P + + ++ ++ +ER + ++ E+ + +R+E+ + +E L
Sbjct: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQQ-----ERREQRLKREEEEER---LEQRL 672
Query: 124 KKRKGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAK 183
K+ EHEE++ + + AE+ + E I+ S K + L ++ DA+
Sbjct: 673 KR-----EHEEERREQELAEEEQEQARERIK-SRIPKWQWQLESE-----------ADAR 715
Query: 184 IKNIIS----TEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNR-----FYHEELNA 234
+ S E + R E++ ++++SE + A Q + +
Sbjct: 716 QSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEE 775
Query: 235 PIRRNKEEPKARP---------LRVGDTEKPE-----PERSPPNRKRPANEKATDDYHYE 280
R ++ ARP LR + ++ E E R+R E+ + E
Sbjct: 776 KSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLE 835
Query: 281 KFKKMNRR 288
+ +++ RR
Sbjct: 836 EEEQLQRR 843
Score = 28.1 bits (61), Expect = 9.4
Identities = 53/268 (19%), Positives = 99/268 (36%), Gaps = 37/268 (13%)
Query: 10 RRRGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPF 69
RR+G E ++ ++ ++ + EE +E RKR V EK+QEE
Sbjct: 219 RRKGREEKQQQRRERQDRVFQEEEEKE---WRKR----ETVLRKEEEKLQEEEP------ 265
Query: 70 QMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKGI 129
+R ++ EEE L R++E+ + + +RK
Sbjct: 266 --------------QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQE 311
Query: 130 VEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIIS 189
E EQ+ + + ++ E E R ++ +E Q L E + + +++
Sbjct: 312 EERREQQEERREQQE-RREQQEERREQQLRREQEERREQQLRREQEEERR-EQQLRREQE 369
Query: 190 TEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKEEPKARPLR 249
E + +L EQQ +++ + + E+ +RR ++ + + LR
Sbjct: 370 EERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ---QLRREQQLRREQQLR 426
Query: 250 VGDTE-----KPEPERSPPNRKRPANEK 272
E K E ER KR E+
Sbjct: 427 REQEEERHEQKHEQERREQRLKREQEER 454
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 37.4 bits (85), Expect = 0.015
Identities = 44/234 (18%), Positives = 95/234 (40%), Gaps = 7/234 (2%)
Query: 11 RRGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSA--VALLVGEKVQEETTLVDDP 68
RR + E+ Q E + T E + R+ A + L V E + + +D
Sbjct: 2344 RRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDA 2403
Query: 69 FQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKG 128
+ + +KL + +++ +E + L + + + D DA+ ++ EL++ K
Sbjct: 2404 QRFRKQAEEIGEKLH---RTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKE 2460
Query: 129 IVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNII 188
++ E + ++ K+ E + + ++ + A + + L AK++ +
Sbjct: 2461 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2520
Query: 189 STEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKEE 242
E AKA+ L E+Q +++ V ++ R E +RR +EE
Sbjct: 2521 QDEVAKAQQLREEQQRQQQQMEQ--ERQRLVASMEEARRRQHEAEEGVRRKQEE 2572
Score = 30.8 bits (68), Expect = 1.4
Identities = 47/216 (21%), Positives = 84/216 (38%), Gaps = 25/216 (11%)
Query: 12 RGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQM 71
R SE + ++E R + E E LR L E + +
Sbjct: 1779 RSTSEKSKQRLEAEAGRFR-ELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAE 1837
Query: 72 KTGGMVDMKKLKERG----KDKISEEEDLHLGTSFSAETNRRDED-------------AD 114
K + + +LK K+K +E E L A RR E+ A
Sbjct: 1838 KLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQ 1897
Query: 115 MMKYIETELKKRKGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIP 174
+ K ++EL+++KG+V E+ + + E+ + L + ++A K E L +
Sbjct: 1898 LRKASDSELERQKGLV--EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA 1955
Query: 175 EVDLGIDAKIKNIISTEDAKAR-LLAEQQNKKKDSE 209
E L + K E A+ R L AE++ +++++E
Sbjct: 1956 EDTL----RSKEQAELEAARQRQLAAEEERRRREAE 1987
Score = 30.8 bits (68), Expect = 1.4
Identities = 49/240 (20%), Positives = 98/240 (40%), Gaps = 31/240 (12%)
Query: 21 EQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQMKTGGMVDMK 80
EQ+ +RL+LEET +NL + + E ++ + + ++ F ++ M ++
Sbjct: 2185 EQELTTLRLQLEETDHQKNLLDEE--LQRLKAEATEAARQRSQVEEELFSVRV-QMEELS 2241
Query: 81 KLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKGIVEHEEQKVKPK 140
KLK R + +E L L RD+D + ++++ E +K K + E +
Sbjct: 2242 KLKARIE---AENRALIL----------RDKD-NTQRFLQEEAEKMKQVAEEAARLSVAA 2287
Query: 141 NAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIISTEDAKARLLAE 200
L +L E E+ML +M + L +A++ + + LA+
Sbjct: 2288 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQ-------QQKELAQ 2340
Query: 201 QQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKE---EPKARPLRVGDTEKPE 257
+Q ++ + MA + + + L A +R E E + LRV + + +
Sbjct: 2341 EQARRLQEDKE----QMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQ 2396
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 37.4 bits (85), Expect = 0.015
Identities = 44/234 (18%), Positives = 95/234 (40%), Gaps = 7/234 (2%)
Query: 11 RRGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSA--VALLVGEKVQEETTLVDDP 68
RR + E+ Q E + T E + R+ A + L V E + + +D
Sbjct: 2348 RRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDA 2407
Query: 69 FQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKG 128
+ + +KL + +++ +E + L + + + D DA+ ++ EL++ K
Sbjct: 2408 QRFRKQAEEIGEKLH---RTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKE 2464
Query: 129 IVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNII 188
++ E + ++ K+ E + + ++ + A + + L AK++ +
Sbjct: 2465 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2524
Query: 189 STEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKEE 242
E AKA+ L E+Q +++ V ++ R E +RR +EE
Sbjct: 2525 QDEVAKAQQLREEQQRQQQQMEQ--ERQRLVASMEEARRRQHEAEEGVRRKQEE 2576
Score = 30.8 bits (68), Expect = 1.4
Identities = 47/216 (21%), Positives = 84/216 (38%), Gaps = 25/216 (11%)
Query: 12 RGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQM 71
R SE + ++E R + E E LR L E + +
Sbjct: 1783 RSTSEKSKQRLEAEAGRFR-ELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAE 1841
Query: 72 KTGGMVDMKKLKERG----KDKISEEEDLHLGTSFSAETNRRDED-------------AD 114
K + + +LK K+K +E E L A RR E+ A
Sbjct: 1842 KLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQ 1901
Query: 115 MMKYIETELKKRKGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIP 174
+ K ++EL+++KG+V E+ + + E+ + L + ++A K E L +
Sbjct: 1902 LRKASDSELERQKGLV--EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA 1959
Query: 175 EVDLGIDAKIKNIISTEDAKAR-LLAEQQNKKKDSE 209
E L + K E A+ R L AE++ +++++E
Sbjct: 1960 EDTL----RSKEQAELEAARQRQLAAEEERRRREAE 1991
Score = 30.8 bits (68), Expect = 1.4
Identities = 49/240 (20%), Positives = 98/240 (40%), Gaps = 31/240 (12%)
Query: 21 EQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQMKTGGMVDMK 80
EQ+ +RL+LEET +NL + + E ++ + + ++ F ++ M ++
Sbjct: 2189 EQELTTLRLQLEETDHQKNLLDEE--LQRLKAEATEAARQRSQVEEELFSVRV-QMEELS 2245
Query: 81 KLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKGIVEHEEQKVKPK 140
KLK R + +E L L RD+D + ++++ E +K K + E +
Sbjct: 2246 KLKARIE---AENRALIL----------RDKD-NTQRFLQEEAEKMKQVAEEAARLSVAA 2291
Query: 141 NAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIISTEDAKARLLAE 200
L +L E E+ML +M + L +A++ + + LA+
Sbjct: 2292 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQ-------QQKELAQ 2344
Query: 201 QQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKE---EPKARPLRVGDTEKPE 257
+Q ++ + MA + + + L A +R E E + LRV + + +
Sbjct: 2345 EQARRLQEDKE----QMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQ 2400
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 37.4 bits (85), Expect = 0.015
Identities = 44/234 (18%), Positives = 95/234 (40%), Gaps = 7/234 (2%)
Query: 11 RRGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSA--VALLVGEKVQEETTLVDDP 68
RR + E+ Q E + T E + R+ A + L V E + + +D
Sbjct: 2344 RRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDA 2403
Query: 69 FQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKG 128
+ + +KL + +++ +E + L + + + D DA+ ++ EL++ K
Sbjct: 2404 QRFRKQAEEIGEKLH---RTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKE 2460
Query: 129 IVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNII 188
++ E + ++ K+ E + + ++ + A + + L AK++ +
Sbjct: 2461 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2520
Query: 189 STEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKEE 242
E AKA+ L E+Q +++ V ++ R E +RR +EE
Sbjct: 2521 QDEVAKAQQLREEQQRQQQQMEQ--ERQRLVASMEEARRRQHEAEEGVRRKQEE 2572
Score = 30.8 bits (68), Expect = 1.4
Identities = 47/216 (21%), Positives = 84/216 (38%), Gaps = 25/216 (11%)
Query: 12 RGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQM 71
R SE + ++E R + E E LR L E + +
Sbjct: 1779 RSTSEKSKQRLEAEAGRFR-ELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAE 1837
Query: 72 KTGGMVDMKKLKERG----KDKISEEEDLHLGTSFSAETNRRDED-------------AD 114
K + + +LK K+K +E E L A RR E+ A
Sbjct: 1838 KLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQ 1897
Query: 115 MMKYIETELKKRKGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIP 174
+ K ++EL+++KG+V E+ + + E+ + L + ++A K E L +
Sbjct: 1898 LRKASDSELERQKGLV--EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA 1955
Query: 175 EVDLGIDAKIKNIISTEDAKAR-LLAEQQNKKKDSE 209
E L + K E A+ R L AE++ +++++E
Sbjct: 1956 EDTL----RSKEQAELEAARQRQLAAEEERRRREAE 1987
Score = 30.8 bits (68), Expect = 1.4
Identities = 49/240 (20%), Positives = 98/240 (40%), Gaps = 31/240 (12%)
Query: 21 EQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQMKTGGMVDMK 80
EQ+ +RL+LEET +NL + + E ++ + + ++ F ++ M ++
Sbjct: 2185 EQELTTLRLQLEETDHQKNLLDEE--LQRLKAEATEAARQRSQVEEELFSVRV-QMEELS 2241
Query: 81 KLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKGIVEHEEQKVKPK 140
KLK R + +E L L RD+D + ++++ E +K K + E +
Sbjct: 2242 KLKARIE---AENRALIL----------RDKD-NTQRFLQEEAEKMKQVAEEAARLSVAA 2287
Query: 141 NAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIISTEDAKARLLAE 200
L +L E E+ML +M + L +A++ + + LA+
Sbjct: 2288 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQ-------QQKELAQ 2340
Query: 201 QQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKE---EPKARPLRVGDTEKPE 257
+Q ++ + MA + + + L A +R E E + LRV + + +
Sbjct: 2341 EQARRLQEDKE----QMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQ 2396
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 37.4 bits (85), Expect = 0.015
Identities = 44/234 (18%), Positives = 95/234 (40%), Gaps = 7/234 (2%)
Query: 11 RRGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSA--VALLVGEKVQEETTLVDDP 68
RR + E+ Q E + T E + R+ A + L V E + + +D
Sbjct: 2312 RRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDA 2371
Query: 69 FQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKG 128
+ + +KL + +++ +E + L + + + D DA+ ++ EL++ K
Sbjct: 2372 QRFRKQAEEIGEKLH---RTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKE 2428
Query: 129 IVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNII 188
++ E + ++ K+ E + + ++ + A + + L AK++ +
Sbjct: 2429 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2488
Query: 189 STEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKEE 242
E AKA+ L E+Q +++ V ++ R E +RR +EE
Sbjct: 2489 QDEVAKAQQLREEQQRQQQQMEQ--ERQRLVASMEEARRRQHEAEEGVRRKQEE 2540
Score = 30.8 bits (68), Expect = 1.4
Identities = 47/216 (21%), Positives = 84/216 (38%), Gaps = 25/216 (11%)
Query: 12 RGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQM 71
R SE + ++E R + E E LR L E + +
Sbjct: 1747 RSTSEKSKQRLEAEAGRFR-ELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAE 1805
Query: 72 KTGGMVDMKKLKERG----KDKISEEEDLHLGTSFSAETNRRDED-------------AD 114
K + + +LK K+K +E E L A RR E+ A
Sbjct: 1806 KLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQ 1865
Query: 115 MMKYIETELKKRKGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIP 174
+ K ++EL+++KG+V E+ + + E+ + L + ++A K E L +
Sbjct: 1866 LRKASDSELERQKGLV--EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA 1923
Query: 175 EVDLGIDAKIKNIISTEDAKAR-LLAEQQNKKKDSE 209
E L + K E A+ R L AE++ +++++E
Sbjct: 1924 EDTL----RSKEQAELEAARQRQLAAEEERRRREAE 1955
Score = 30.8 bits (68), Expect = 1.4
Identities = 49/240 (20%), Positives = 98/240 (40%), Gaps = 31/240 (12%)
Query: 21 EQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQMKTGGMVDMK 80
EQ+ +RL+LEET +NL + + E ++ + + ++ F ++ M ++
Sbjct: 2153 EQELTTLRLQLEETDHQKNLLDEE--LQRLKAEATEAARQRSQVEEELFSVRV-QMEELS 2209
Query: 81 KLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKGIVEHEEQKVKPK 140
KLK R + +E L L RD+D + ++++ E +K K + E +
Sbjct: 2210 KLKARIE---AENRALIL----------RDKD-NTQRFLQEEAEKMKQVAEEAARLSVAA 2255
Query: 141 NAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIISTEDAKARLLAE 200
L +L E E+ML +M + L +A++ + + LA+
Sbjct: 2256 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQ-------QQKELAQ 2308
Query: 201 QQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKE---EPKARPLRVGDTEKPE 257
+Q ++ + MA + + + L A +R E E + LRV + + +
Sbjct: 2309 EQARRLQEDKE----QMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQ 2364
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 37.4 bits (85), Expect = 0.015
Identities = 44/234 (18%), Positives = 95/234 (40%), Gaps = 7/234 (2%)
Query: 11 RRGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSA--VALLVGEKVQEETTLVDDP 68
RR + E+ Q E + T E + R+ A + L V E + + +D
Sbjct: 2481 RRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDA 2540
Query: 69 FQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKG 128
+ + +KL + +++ +E + L + + + D DA+ ++ EL++ K
Sbjct: 2541 QRFRKQAEEIGEKLH---RTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKE 2597
Query: 129 IVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNII 188
++ E + ++ K+ E + + ++ + A + + L AK++ +
Sbjct: 2598 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2657
Query: 189 STEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKEE 242
E AKA+ L E+Q +++ V ++ R E +RR +EE
Sbjct: 2658 QDEVAKAQQLREEQQRQQQQMEQ--ERQRLVASMEEARRRQHEAEEGVRRKQEE 2709
Score = 30.8 bits (68), Expect = 1.4
Identities = 47/216 (21%), Positives = 84/216 (38%), Gaps = 25/216 (11%)
Query: 12 RGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQM 71
R SE + ++E R + E E LR L E + +
Sbjct: 1916 RSTSEKSKQRLEAEAGRFR-ELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAE 1974
Query: 72 KTGGMVDMKKLKERG----KDKISEEEDLHLGTSFSAETNRRDED-------------AD 114
K + + +LK K+K +E E L A RR E+ A
Sbjct: 1975 KLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQ 2034
Query: 115 MMKYIETELKKRKGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIP 174
+ K ++EL+++KG+V E+ + + E+ + L + ++A K E L +
Sbjct: 2035 LRKASDSELERQKGLV--EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA 2092
Query: 175 EVDLGIDAKIKNIISTEDAKAR-LLAEQQNKKKDSE 209
E L + K E A+ R L AE++ +++++E
Sbjct: 2093 EDTL----RSKEQAELEAARQRQLAAEEERRRREAE 2124
Score = 30.8 bits (68), Expect = 1.4
Identities = 49/240 (20%), Positives = 98/240 (40%), Gaps = 31/240 (12%)
Query: 21 EQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQMKTGGMVDMK 80
EQ+ +RL+LEET +NL + + E ++ + + ++ F ++ M ++
Sbjct: 2322 EQELTTLRLQLEETDHQKNLLDEE--LQRLKAEATEAARQRSQVEEELFSVRV-QMEELS 2378
Query: 81 KLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKGIVEHEEQKVKPK 140
KLK R + +E L L RD+D + ++++ E +K K + E +
Sbjct: 2379 KLKARIE---AENRALIL----------RDKD-NTQRFLQEEAEKMKQVAEEAARLSVAA 2424
Query: 141 NAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIISTEDAKARLLAE 200
L +L E E+ML +M + L +A++ + + LA+
Sbjct: 2425 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQ-------QQKELAQ 2477
Query: 201 QQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKE---EPKARPLRVGDTEKPE 257
+Q ++ + MA + + + L A +R E E + LRV + + +
Sbjct: 2478 EQARRLQEDKE----QMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQ 2533
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 37.4 bits (85), Expect = 0.015
Identities = 44/234 (18%), Positives = 95/234 (40%), Gaps = 7/234 (2%)
Query: 11 RRGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSA--VALLVGEKVQEETTLVDDP 68
RR + E+ Q E + T E + R+ A + L V E + + +D
Sbjct: 2322 RRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDA 2381
Query: 69 FQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKG 128
+ + +KL + +++ +E + L + + + D DA+ ++ EL++ K
Sbjct: 2382 QRFRKQAEEIGEKLH---RTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKE 2438
Query: 129 IVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNII 188
++ E + ++ K+ E + + ++ + A + + L AK++ +
Sbjct: 2439 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2498
Query: 189 STEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKEE 242
E AKA+ L E+Q +++ V ++ R E +RR +EE
Sbjct: 2499 QDEVAKAQQLREEQQRQQQQMEQ--ERQRLVASMEEARRRQHEAEEGVRRKQEE 2550
Score = 30.8 bits (68), Expect = 1.4
Identities = 47/216 (21%), Positives = 84/216 (38%), Gaps = 25/216 (11%)
Query: 12 RGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQM 71
R SE + ++E R + E E LR L E + +
Sbjct: 1757 RSTSEKSKQRLEAEAGRFR-ELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAE 1815
Query: 72 KTGGMVDMKKLKERG----KDKISEEEDLHLGTSFSAETNRRDED-------------AD 114
K + + +LK K+K +E E L A RR E+ A
Sbjct: 1816 KLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQ 1875
Query: 115 MMKYIETELKKRKGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIP 174
+ K ++EL+++KG+V E+ + + E+ + L + ++A K E L +
Sbjct: 1876 LRKASDSELERQKGLV--EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA 1933
Query: 175 EVDLGIDAKIKNIISTEDAKAR-LLAEQQNKKKDSE 209
E L + K E A+ R L AE++ +++++E
Sbjct: 1934 EDTL----RSKEQAELEAARQRQLAAEEERRRREAE 1965
Score = 30.8 bits (68), Expect = 1.4
Identities = 49/240 (20%), Positives = 98/240 (40%), Gaps = 31/240 (12%)
Query: 21 EQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQMKTGGMVDMK 80
EQ+ +RL+LEET +NL + + E ++ + + ++ F ++ M ++
Sbjct: 2163 EQELTTLRLQLEETDHQKNLLDEE--LQRLKAEATEAARQRSQVEEELFSVRV-QMEELS 2219
Query: 81 KLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKGIVEHEEQKVKPK 140
KLK R + +E L L RD+D + ++++ E +K K + E +
Sbjct: 2220 KLKARIE---AENRALIL----------RDKD-NTQRFLQEEAEKMKQVAEEAARLSVAA 2265
Query: 141 NAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIISTEDAKARLLAE 200
L +L E E+ML +M + L +A++ + + LA+
Sbjct: 2266 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQ-------QQKELAQ 2318
Query: 201 QQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKE---EPKARPLRVGDTEKPE 257
+Q ++ + MA + + + L A +R E E + LRV + + +
Sbjct: 2319 EQARRLQEDKE----QMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQ 2374
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 37.4 bits (85), Expect = 0.015
Identities = 44/234 (18%), Positives = 95/234 (40%), Gaps = 7/234 (2%)
Query: 11 RRGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSA--VALLVGEKVQEETTLVDDP 68
RR + E+ Q E + T E + R+ A + L V E + + +D
Sbjct: 2330 RRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDA 2389
Query: 69 FQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKG 128
+ + +KL + +++ +E + L + + + D DA+ ++ EL++ K
Sbjct: 2390 QRFRKQAEEIGEKLH---RTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKE 2446
Query: 129 IVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNII 188
++ E + ++ K+ E + + ++ + A + + L AK++ +
Sbjct: 2447 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2506
Query: 189 STEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKEE 242
E AKA+ L E+Q +++ V ++ R E +RR +EE
Sbjct: 2507 QDEVAKAQQLREEQQRQQQQMEQ--ERQRLVASMEEARRRQHEAEEGVRRKQEE 2558
Score = 30.8 bits (68), Expect = 1.4
Identities = 47/216 (21%), Positives = 84/216 (38%), Gaps = 25/216 (11%)
Query: 12 RGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQM 71
R SE + ++E R + E E LR L E + +
Sbjct: 1765 RSTSEKSKQRLEAEAGRFR-ELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAE 1823
Query: 72 KTGGMVDMKKLKERG----KDKISEEEDLHLGTSFSAETNRRDED-------------AD 114
K + + +LK K+K +E E L A RR E+ A
Sbjct: 1824 KLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQ 1883
Query: 115 MMKYIETELKKRKGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIP 174
+ K ++EL+++KG+V E+ + + E+ + L + ++A K E L +
Sbjct: 1884 LRKASDSELERQKGLV--EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA 1941
Query: 175 EVDLGIDAKIKNIISTEDAKAR-LLAEQQNKKKDSE 209
E L + K E A+ R L AE++ +++++E
Sbjct: 1942 EDTL----RSKEQAELEAARQRQLAAEEERRRREAE 1973
Score = 30.8 bits (68), Expect = 1.4
Identities = 49/240 (20%), Positives = 98/240 (40%), Gaps = 31/240 (12%)
Query: 21 EQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQMKTGGMVDMK 80
EQ+ +RL+LEET +NL + + E ++ + + ++ F ++ M ++
Sbjct: 2171 EQELTTLRLQLEETDHQKNLLDEE--LQRLKAEATEAARQRSQVEEELFSVRV-QMEELS 2227
Query: 81 KLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKGIVEHEEQKVKPK 140
KLK R + +E L L RD+D + ++++ E +K K + E +
Sbjct: 2228 KLKARIE---AENRALIL----------RDKD-NTQRFLQEEAEKMKQVAEEAARLSVAA 2273
Query: 141 NAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIISTEDAKARLLAE 200
L +L E E+ML +M + L +A++ + + LA+
Sbjct: 2274 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQ-------QQKELAQ 2326
Query: 201 QQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKE---EPKARPLRVGDTEKPE 257
+Q ++ + MA + + + L A +R E E + LRV + + +
Sbjct: 2327 EQARRLQEDKE----QMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQ 2382
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 37.4 bits (85), Expect = 0.015
Identities = 44/234 (18%), Positives = 95/234 (40%), Gaps = 7/234 (2%)
Query: 11 RRGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSA--VALLVGEKVQEETTLVDDP 68
RR + E+ Q E + T E + R+ A + L V E + + +D
Sbjct: 2371 RRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDA 2430
Query: 69 FQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKG 128
+ + +KL + +++ +E + L + + + D DA+ ++ EL++ K
Sbjct: 2431 QRFRKQAEEIGEKLH---RTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKE 2487
Query: 129 IVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNII 188
++ E + ++ K+ E + + ++ + A + + L AK++ +
Sbjct: 2488 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2547
Query: 189 STEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKEE 242
E AKA+ L E+Q +++ V ++ R E +RR +EE
Sbjct: 2548 QDEVAKAQQLREEQQRQQQQMEQ--ERQRLVASMEEARRRQHEAEEGVRRKQEE 2599
Score = 30.8 bits (68), Expect = 1.4
Identities = 47/216 (21%), Positives = 84/216 (38%), Gaps = 25/216 (11%)
Query: 12 RGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQM 71
R SE + ++E R + E E LR L E + +
Sbjct: 1806 RSTSEKSKQRLEAEAGRFR-ELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAE 1864
Query: 72 KTGGMVDMKKLKERG----KDKISEEEDLHLGTSFSAETNRRDED-------------AD 114
K + + +LK K+K +E E L A RR E+ A
Sbjct: 1865 KLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQ 1924
Query: 115 MMKYIETELKKRKGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIP 174
+ K ++EL+++KG+V E+ + + E+ + L + ++A K E L +
Sbjct: 1925 LRKASDSELERQKGLV--EDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNA 1982
Query: 175 EVDLGIDAKIKNIISTEDAKAR-LLAEQQNKKKDSE 209
E L + K E A+ R L AE++ +++++E
Sbjct: 1983 EDTL----RSKEQAELEAARQRQLAAEEERRRREAE 2014
Score = 30.8 bits (68), Expect = 1.4
Identities = 49/240 (20%), Positives = 98/240 (40%), Gaps = 31/240 (12%)
Query: 21 EQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQMKTGGMVDMK 80
EQ+ +RL+LEET +NL + + E ++ + + ++ F ++ M ++
Sbjct: 2212 EQELTTLRLQLEETDHQKNLLDEE--LQRLKAEATEAARQRSQVEEELFSVRV-QMEELS 2268
Query: 81 KLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKGIVEHEEQKVKPK 140
KLK R + +E L L RD+D + ++++ E +K K + E +
Sbjct: 2269 KLKARIE---AENRALIL----------RDKD-NTQRFLQEEAEKMKQVAEEAARLSVAA 2314
Query: 141 NAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIISTEDAKARLLAE 200
L +L E E+ML +M + L +A++ + + LA+
Sbjct: 2315 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQ-------QQKELAQ 2367
Query: 201 QQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKE---EPKARPLRVGDTEKPE 257
+Q ++ + MA + + + L A +R E E + LRV + + +
Sbjct: 2368 EQARRLQEDKE----QMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQ 2423
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 37.0 bits (84), Expect = 0.020
Identities = 46/213 (21%), Positives = 94/213 (44%), Gaps = 19/213 (8%)
Query: 9 RRRRGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKV--QEETTLVD 66
+RRR + E + +E + E + + E REVQ L++R + EKV ++ L
Sbjct: 1393 QRRRTELERQLEELERER-QARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQ 1451
Query: 67 DPFQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSA-ETNRRDEDADMMKYIETELKK 125
DP Q + ++ ++ +E+ + ++ E E L +A E E + + ++ E
Sbjct: 1452 DPQQAREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVE--- 1508
Query: 126 RKGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIK 185
KG E E Q++K E+ S +K+ ++ +++ + + E++ K
Sbjct: 1509 -KGDTEQEIQRLKSSLEEE-----------SRSKRELDVEVSRLEARLSELEFHNSKSSK 1556
Query: 186 NIISTEDAKARLLAEQQNKKKDSETSFVPTNMA 218
+ + +L E+QN + ++ NMA
Sbjct: 1557 ELDFLREENHKLQLERQNLQLETRRLQSEINMA 1589
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 36.2 bits (82), Expect = 0.034
Identities = 44/188 (23%), Positives = 85/188 (45%), Gaps = 51/188 (27%)
Query: 14 DSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQMKT 73
+ EE+E++ EEVR + EE +E + ++ EK +EE
Sbjct: 2249 EEREEEEEREEEEVREEEEERKEEEEGEEKQ----------VEKEEEE------------ 2286
Query: 74 GGMVDMKKLKERGKDKISEEEDL-----HLGTSFSAETNRRDEDADMMKYIETELKKRKG 128
KK KE+ K+++ E+E++ + + E+ +E+ + +E E+ + K
Sbjct: 2287 ----KKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKE 2342
Query: 129 IVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPE-----VDLGI-DA 182
I++ E+Q ++L E R S + E +LS +L G+P + LG+ +
Sbjct: 2343 ILKKEKQ-----------FKLQEQ-RRKSLRGRERVLS--ILRGVPHGKGRAIRLGVLKS 2388
Query: 183 KIKNIIST 190
+K ++ST
Sbjct: 2389 PLKKLMST 2396
Score = 28.1 bits (61), Expect = 9.4
Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 9/117 (7%)
Query: 55 GEKVQEETTLVDDPFQMKTGGMVDMKKLK---ERGKDKISEEEDLHLGTSFSAETNRRDE 111
G+K +E+ + D + + +M+ L E+ + SEEE+ E R+E
Sbjct: 2206 GDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREE 2265
Query: 112 DADMMKYIETELKKRKGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQ 168
+ + + E E K+ VE EE++ K K E E+ E V K EE++S +
Sbjct: 2266 EEERKEEEEGEEKQ----VEKEEEEKKKKKKEKKKEEVQEKEEVFEEK--EEIMSEE 2316
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 36.2 bits (82), Expect = 0.034
Identities = 42/151 (27%), Positives = 64/151 (42%), Gaps = 22/151 (14%)
Query: 5 RKIFRRRRGDSESE-------EDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEK 57
RK RR D E+E E E++ E R K E RE + R+R E+
Sbjct: 285 RKRQRRTERDRETERKRERQRERERERERNR-KRERERERERERERQRETERDREKERER 343
Query: 58 VQEETTLVDDPFQMKTG----GMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDA 113
++ T +D +TG + ++ +ER +D+ S E E RD D
Sbjct: 344 KRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSARE---------REERERDRDR 394
Query: 114 DMMKYIETELKK-RKGIVEHEEQKVKPKNAE 143
D K E + +K R G E E+Q+ + K+ E
Sbjct: 395 DRQKERERQTEKDRDGQRETEKQREREKDRE 425
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 36.2 bits (82), Expect = 0.034
Identities = 62/280 (22%), Positives = 110/280 (39%), Gaps = 30/280 (10%)
Query: 18 EEDEQDSEEVRLKLEETRE------VQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQM 71
+E S EVR K+ ET+E + +K +G+S +A +K Q + T DD Q
Sbjct: 889 KEQSFTSLEVR-KVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS 947
Query: 72 KTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKGIVE 131
K G + KK + K I E+ + + + R+E K I+ + + G +
Sbjct: 948 KK-GTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIK---QIKNGTTD 1003
Query: 132 HEEQKVKPKNAEDCLYELPENIRVSSAKKTEEM--LSNQMLSGIPEVDLGIDAKIKN-II 188
E++ K IR ++KK +E+ + + D D K KN
Sbjct: 1004 GEKKSKK--------------IRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAY 1049
Query: 189 STEDAKARLLAEQQNKKKDSETSFVPT-NMAVNYVQHNRFYHEELNAPIRRN-KEEPKAR 246
E + +LL + K++D +S +M + + + + RRN + +
Sbjct: 1050 GREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTK 1109
Query: 247 PLRVGDTEKPEPERSPPNRKRPANEKATDDYHYEKFKKMN 286
++ G + E S N+K+ + K KK N
Sbjct: 1110 EIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRN 1149
Score = 31.6 bits (70), Expect = 0.85
Identities = 69/308 (22%), Positives = 119/308 (38%), Gaps = 63/308 (20%)
Query: 6 KIFRRRRGDSESE-------EDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKV 58
K R+R+ S S+ ED +S + RLK E RE +NL + N +++
Sbjct: 1061 KSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRN---------TKEI 1111
Query: 59 QEETTLVDDPFQMKTGGMVDMKKLKERGKDK-----ISEEEDLHLGTSFSAETNRRDEDA 113
Q ++ D + D KK K+R K + E++ L T S + + D +
Sbjct: 1112 QSGSSSSDAEESSE-----DNKKKKQRTSSKKKAVIVKEKKRNSLRT--STKRKQADITS 1164
Query: 114 DMMKYIETELKKRKGIVEHEEQKVKPKNAEDCLYELPENIRVSS-----AKKTEEMLSNQ 168
IE + + G +EQK+KP + EN+ +SS +E LS
Sbjct: 1165 SSSSDIEDDDQNSIGEGSSDEQKIKP---------VTENLVLSSHTGFCQSSGDEALSKS 1215
Query: 169 MLSGIPEVDLGIDA--KIKNIISTEDAKARLLAEQQNKKKDS-ETSFVPTNMAVNYVQHN 225
+ + + D D +I + E+ KA L +++ D E T +
Sbjct: 1216 VPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGD 1275
Query: 226 RFYHEELNAPIRRNKEEPK---------ARPLRVGDTEKPEPERSPP---------NRKR 267
++N+ + EE K L V D E E +++ P NR++
Sbjct: 1276 EEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRK 1335
Query: 268 PANEKATD 275
++E + D
Sbjct: 1336 VSSEDSED 1343
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 36.2 bits (82), Expect = 0.034
Identities = 62/280 (22%), Positives = 110/280 (39%), Gaps = 30/280 (10%)
Query: 18 EEDEQDSEEVRLKLEETRE------VQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQM 71
+E S EVR K+ ET+E + +K +G+S +A +K Q + T DD Q
Sbjct: 927 KEQSFTSLEVR-KVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS 985
Query: 72 KTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKGIVE 131
K G + KK + K I E+ + + + R+E K I+ + + G +
Sbjct: 986 KK-GTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIK---QIKNGTTD 1041
Query: 132 HEEQKVKPKNAEDCLYELPENIRVSSAKKTEEM--LSNQMLSGIPEVDLGIDAKIKN-II 188
E++ K IR ++KK +E+ + + D D K KN
Sbjct: 1042 GEKKSKK--------------IRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAY 1087
Query: 189 STEDAKARLLAEQQNKKKDSETSFVPT-NMAVNYVQHNRFYHEELNAPIRRN-KEEPKAR 246
E + +LL + K++D +S +M + + + + RRN + +
Sbjct: 1088 GREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTK 1147
Query: 247 PLRVGDTEKPEPERSPPNRKRPANEKATDDYHYEKFKKMN 286
++ G + E S N+K+ + K KK N
Sbjct: 1148 EIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRN 1187
Score = 31.6 bits (70), Expect = 0.85
Identities = 69/308 (22%), Positives = 119/308 (38%), Gaps = 63/308 (20%)
Query: 6 KIFRRRRGDSESE-------EDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKV 58
K R+R+ S S+ ED +S + RLK E RE +NL + N +++
Sbjct: 1099 KSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRN---------TKEI 1149
Query: 59 QEETTLVDDPFQMKTGGMVDMKKLKERGKDK-----ISEEEDLHLGTSFSAETNRRDEDA 113
Q ++ D + D KK K+R K + E++ L T S + + D +
Sbjct: 1150 QSGSSSSDAEESSE-----DNKKKKQRTSSKKKAVIVKEKKRNSLRT--STKRKQADITS 1202
Query: 114 DMMKYIETELKKRKGIVEHEEQKVKPKNAEDCLYELPENIRVSS-----AKKTEEMLSNQ 168
IE + + G +EQK+KP + EN+ +SS +E LS
Sbjct: 1203 SSSSDIEDDDQNSIGEGSSDEQKIKP---------VTENLVLSSHTGFCQSSGDEALSKS 1253
Query: 169 MLSGIPEVDLGIDA--KIKNIISTEDAKARLLAEQQNKKKDS-ETSFVPTNMAVNYVQHN 225
+ + + D D +I + E+ KA L +++ D E T +
Sbjct: 1254 VPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGD 1313
Query: 226 RFYHEELNAPIRRNKEEPK---------ARPLRVGDTEKPEPERSPP---------NRKR 267
++N+ + EE K L V D E E +++ P NR++
Sbjct: 1314 EEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRK 1373
Query: 268 PANEKATD 275
++E + D
Sbjct: 1374 VSSEDSED 1381
>gi|155030242 WD repeat domain 60 [Homo sapiens]
Length = 1066
Score = 36.2 bits (82), Expect = 0.034
Identities = 46/247 (18%), Positives = 109/247 (44%), Gaps = 31/247 (12%)
Query: 57 KVQEETTLVDDP----FQMKTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDED 112
+ +++T DD + +++GG + +K +E+ K+ +E ++ L D+D
Sbjct: 7 RTKDDTWKADDLRKHLWAIQSGGSKEERKHREK---KLRKESEMDLPEHKEPRCRDPDQD 63
Query: 113 A---DMMKYIETELKKRKGIVEHEEQKVKPKNAEDCLYE-LPENIRVSSA---------- 158
A D + + T + +G + + Q+ + ++A+D E L E R +
Sbjct: 64 ARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREK 123
Query: 159 KKTEEMLSNQMLSGIPEVDL-GIDAKIKNIISTEDAKARLLAEQQNKKKDSETSFVPTNM 217
+K ++ + +L G + + + ++ + K R +++ ++++KD ++ +
Sbjct: 124 EKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDR 183
Query: 218 AVNYVQHNRFYHEELNAPIR--RNKEEPKARPLRVGDTEKP-EPERSPPNRKRPANEKAT 274
Y + Y + + P++ KEE + R KP EP+R +R++ + +
Sbjct: 184 ERRYRERKLQYGDSKDNPLKYWLYKEEGERR------HRKPREPDRDNKHREKSSTREKR 237
Query: 275 DDYHYEK 281
+ Y EK
Sbjct: 238 EKYSKEK 244
>gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens]
Length = 258
Score = 35.8 bits (81), Expect = 0.045
Identities = 36/138 (26%), Positives = 61/138 (44%), Gaps = 28/138 (20%)
Query: 16 ESEEDEQDSEEVRLKLEETREVQNLRKRPNG-VSAVALLVGEKVQ--------------E 60
E EE+ Q+ EEV+ E+T E ++P ++A + GEKV E
Sbjct: 14 EEEEEAQEEEEVQ---EDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLME 70
Query: 61 ETTLVDDPFQMKTGGMVDMKKLKER---------GKDKISEEEDLHLGTSFSAETNRRDE 111
L+D F+ + ++ LKER + +I E++ + E RR+E
Sbjct: 71 LQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREE 130
Query: 112 DADMMKYIETELKKRKGI 129
+ D + E +LKK+K +
Sbjct: 131 E-DAKRRAEDDLKKKKAL 147
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 35.8 bits (81), Expect = 0.045
Identities = 59/274 (21%), Positives = 107/274 (39%), Gaps = 41/274 (14%)
Query: 18 EEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQMKTGGMV 77
++D + S+ K ++RE + R R + EK++E+ + + + +
Sbjct: 345 QKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK-RKDTREKIKEKERVKEKDREKEREREK 403
Query: 78 DMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKGIVEHEEQKV 137
+ +K KERGK+K ++E +D + D K E E +K EHE+ +
Sbjct: 404 EREKEKERGKNKDRDKE------------REKDREKDKEKDREREREK-----EHEKDRD 446
Query: 138 KPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIISTEDAKARL 197
K K E + E R +K+ +E S P + ++ S+ + + R
Sbjct: 447 KEKEKEQDKEKEREKDR---SKEIDEKRKKDKKSRTPPRSYNASRRSRS--SSRERRRRR 501
Query: 198 LAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKEEPKARPLRVGDTEKPE 257
+ S+T ++ + + P RNK++ K R +E+ E
Sbjct: 502 SRSSSRSPRTSKTIKRKSSRSPS--------------PRSRNKKDKKREKERDHISERRE 547
Query: 258 PERSPPNRK----RPANEKATDDYHYEKFKKMNR 287
ERS RK R EK + K K+ N+
Sbjct: 548 RERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNK 581
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 35.8 bits (81), Expect = 0.045
Identities = 59/274 (21%), Positives = 107/274 (39%), Gaps = 41/274 (14%)
Query: 18 EEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQMKTGGMV 77
++D + S+ K ++RE + R R + EK++E+ + + + +
Sbjct: 229 QKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK-RKDTREKIKEKERVKEKDREKEREREK 287
Query: 78 DMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKGIVEHEEQKV 137
+ +K KERGK+K ++E +D + D K E E +K EHE+ +
Sbjct: 288 EREKEKERGKNKDRDKE------------REKDREKDKEKDREREREK-----EHEKDRD 330
Query: 138 KPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVDLGIDAKIKNIISTEDAKARL 197
K K E + E R +K+ +E S P + ++ S+ + + R
Sbjct: 331 KEKEKEQDKEKEREKDR---SKEIDEKRKKDKKSRTPPRSYNASRRSRS--SSRERRRRR 385
Query: 198 LAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNKEEPKARPLRVGDTEKPE 257
+ S+T ++ + + P RNK++ K R +E+ E
Sbjct: 386 SRSSSRSPRTSKTIKRKSSRSPS--------------PRSRNKKDKKREKERDHISERRE 431
Query: 258 PERSPPNRK----RPANEKATDDYHYEKFKKMNR 287
ERS RK R EK + K K+ N+
Sbjct: 432 RERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNK 465
>gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens]
Length = 250
Score = 35.4 bits (80), Expect = 0.059
Identities = 36/139 (25%), Positives = 59/139 (42%), Gaps = 25/139 (17%)
Query: 14 DSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQ-------------- 59
D E E+ E+ EE + +E EVQ K ++A + GEKV
Sbjct: 3 DEEVEQVEEQYEEEE-EAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLM 61
Query: 60 EETTLVDDPFQMKTGGMVDMKKLKER---------GKDKISEEEDLHLGTSFSAETNRRD 110
E L+D F+ + ++ LKER + +I E++ + E RR+
Sbjct: 62 ELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARRE 121
Query: 111 EDADMMKYIETELKKRKGI 129
E+ D + E +LKK+K +
Sbjct: 122 EE-DAKRRAEDDLKKKKAL 139
>gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens]
Length = 250
Score = 35.4 bits (80), Expect = 0.059
Identities = 36/139 (25%), Positives = 59/139 (42%), Gaps = 25/139 (17%)
Query: 14 DSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQ-------------- 59
D E E+ E+ EE + +E EVQ K ++A + GEKV
Sbjct: 3 DEEVEQVEEQYEEEE-EAQEEEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLM 61
Query: 60 EETTLVDDPFQMKTGGMVDMKKLKER---------GKDKISEEEDLHLGTSFSAETNRRD 110
E L+D F+ + ++ LKER + +I E++ + E RR+
Sbjct: 62 ELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARRE 121
Query: 111 EDADMMKYIETELKKRKGI 129
E+ D + E +LKK+K +
Sbjct: 122 EE-DAKRRAEDDLKKKKAL 139
>gi|4503249 DEK oncogene isoform 1 [Homo sapiens]
Length = 375
Score = 35.4 bits (80), Expect = 0.059
Identities = 67/277 (24%), Positives = 108/277 (38%), Gaps = 49/277 (17%)
Query: 12 RGDSESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQM 71
R +SE EEDE D EE + E++ V+ R++ V + ++L +PF +
Sbjct: 29 REESEEEEDEDDEEEEEEEKEKSLIVEGKREKKK--------VERLTMQVSSLQREPFTI 80
Query: 72 KTGGMVDMKKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIETELKKRKGIVE 131
G +G+ K+ E E +H S + D ++ + L R G V
Sbjct: 81 AQG----------KGQ-KLCEIERIHFFLS--------KKKTDELRNLHKLLYNRPGTVS 121
Query: 132 HEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLS---NQMLSGIPEV-DL---GIDA-- 182
++ V + P KK EEML N ML I EV DL G+++
Sbjct: 122 SLKKNVGQFSG------FPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSEL 175
Query: 183 --KIKNIISTEDAKARLLAEQQNKKKDSETSFVPTNMAVNYVQHNRFYHEELNAPIRRNK 240
+I N + + L ++KK S+ S N + + R E+ + +
Sbjct: 176 VKRILNFLMHPKPSGKPL--PKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSD 233
Query: 241 EEPKARPLRVGDTEKPEPERSPPN---RKRPANEKAT 274
E+ K D E E E PP ++ +KAT
Sbjct: 234 EDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKAT 270
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin
(with transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 35.4 bits (80), Expect = 0.059
Identities = 41/204 (20%), Positives = 89/204 (43%), Gaps = 32/204 (15%)
Query: 14 DSESEEDEQDSEEVRLKLEETRE-VQNLRKRPNGVSAVALLVGEKVQEETTLVDDPFQMK 72
D S E+E + E+++ KL+E E + L+ + A EE ++ Q K
Sbjct: 136 DKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEK 195
Query: 73 TGGMVDM-----KKLKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKY-----IETE 122
+ + + E+ ++ E+D ET R + ++++ +ETE
Sbjct: 196 EEFISTLQAQLSQTQAEQAAQQVVREKDARF------ETQVRLHEDELLQLVTQADVETE 249
Query: 123 LKKR-----KGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTEEMLSNQMLSGIPEVD 177
++++ + + EHEE V D L + +++A++ ++LS Q+ E +
Sbjct: 250 MQQKLRVLQRKLEEHEESLVGRAQVVDLLQQ-----ELTAAEQRNQILSQQLQQMEAEHN 304
Query: 178 LGIDAKIKNIISTEDAKARLLAEQ 201
++N + TE ++++L E+
Sbjct: 305 -----TLRNTVETEREESKILLEK 323
>gi|167466187 integrin-binding sialoprotein precursor [Homo sapiens]
Length = 317
Score = 35.0 bits (79), Expect = 0.077
Identities = 37/139 (26%), Positives = 57/139 (41%), Gaps = 9/139 (6%)
Query: 15 SESEEDEQDSEEVRLKLEETREVQNLRKRPNGVSAVALLVGEKVQEETTLVD-DPFQM-K 72
SE EE+E+++ EE+ E ++ +SA L GE T Q+ K
Sbjct: 75 SEEEEEEEETSNEGENNEESNEDEDSEAENTTLSATTLGYGEDATPGTGYTGLAAIQLPK 134
Query: 73 TGGMVDMKKLKERGKDKISEEEDL-HLGTSFSAETNRRDEDADMMKYIETELKKRKGI-- 129
G + K KE+ D+ EEE+ + AE + ++ + TE + G
Sbjct: 135 KAGDITNKATKEKESDEEEEEEEEGNENEESEAEVDENEQGINGTSTNSTEAENGNGSSG 194
Query: 130 ----VEHEEQKVKPKNAED 144
E EE+ V NAED
Sbjct: 195 GDNGEEGEEESVTGANAED 213
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 35.0 bits (79), Expect = 0.077
Identities = 55/292 (18%), Positives = 124/292 (42%), Gaps = 33/292 (11%)
Query: 8 FRRRRGDSESEEDEQDSEEVRLKLEETREVQNLRKRPN----GVSAVALLVG-EKVQEET 62
F+ R + E ++ EE L+E RE K G+SA+ +G V++E
Sbjct: 724 FKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEI 783
Query: 63 TLVDDPFQMKTGGMVDMKK--LKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIE 120
+ +K K+ +KE+ +K+ E + E + D+ + ++
Sbjct: 784 DIEKQEKHIKESKEKPEKRSQIKEKDIEKM-ERKTFEKEKKIKHEHKSEKDKLDLSECVD 842
Query: 121 TELKKRKGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTE------EMLSNQMLSGIP 174
++K++ + H +K C E ++ ++ KKT+ E + + P
Sbjct: 843 -KIKEKDKLYSHHTEK--------CHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKP 893
Query: 175 EVDLGI-DAKIKNIIS-----TEDAKARLLAEQQNKKKDSETSFVPTNM---AVNYVQHN 225
E + + ++K K+++ +++++ + +NK+KD E + ++N
Sbjct: 894 EKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSK 953
Query: 226 RFYHEELNAPIRRNKEEPKARPLRVGDTEKPEPERSPPNRKRPANEKATDDY 277
E+ ++ + NK + + +PL + + K EP ++P +++ +K D Y
Sbjct: 954 HIQEEKKSSIVDGNKAQHE-KPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRY 1004
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 35.0 bits (79), Expect = 0.077
Identities = 55/292 (18%), Positives = 124/292 (42%), Gaps = 33/292 (11%)
Query: 8 FRRRRGDSESEEDEQDSEEVRLKLEETREVQNLRKRPN----GVSAVALLVG-EKVQEET 62
F+ R + E ++ EE L+E RE K G+SA+ +G V++E
Sbjct: 747 FKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEI 806
Query: 63 TLVDDPFQMKTGGMVDMKK--LKERGKDKISEEEDLHLGTSFSAETNRRDEDADMMKYIE 120
+ +K K+ +KE+ +K+ E + E + D+ + ++
Sbjct: 807 DIEKQEKHIKESKEKPEKRSQIKEKDIEKM-ERKTFEKEKKIKHEHKSEKDKLDLSECVD 865
Query: 121 TELKKRKGIVEHEEQKVKPKNAEDCLYELPENIRVSSAKKTE------EMLSNQMLSGIP 174
++K++ + H +K C E ++ ++ KKT+ E + + P
Sbjct: 866 -KIKEKDKLYSHHTEK--------CHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKP 916
Query: 175 EVDLGI-DAKIKNIIS-----TEDAKARLLAEQQNKKKDSETSFVPTNM---AVNYVQHN 225
E + + ++K K+++ +++++ + +NK+KD E + ++N
Sbjct: 917 EKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSK 976
Query: 226 RFYHEELNAPIRRNKEEPKARPLRVGDTEKPEPERSPPNRKRPANEKATDDY 277
E+ ++ + NK + + +PL + + K EP ++P +++ +K D Y
Sbjct: 977 HIQEEKKSSIVDGNKAQHE-KPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRY 1027
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.128 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,082,836
Number of Sequences: 37866
Number of extensions: 535352
Number of successful extensions: 3297
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 210
Number of HSP's that attempted gapping in prelim test: 2982
Number of HSP's gapped (non-prelim): 484
length of query: 289
length of database: 18,247,518
effective HSP length: 101
effective length of query: 188
effective length of database: 14,423,052
effective search space: 2711533776
effective search space used: 2711533776
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.