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Search of human proteins with 14141159
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14141159 heterogeneous nuclear ribonucleoprotein H3 isoform
b [Homo sapiens]
(331 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14141159 heterogeneous nuclear ribonucleoprotein H3 isoform b... 709 0.0
gi|14141157 heterogeneous nuclear ribonucleoprotein H3 isoform a... 699 0.0
gi|5031753 heterogeneous nuclear ribonucleoprotein H1 [Homo sapi... 392 e-109
gi|74099697 heterogeneous nuclear ribonucleoprotein H2 [Homo sap... 391 e-109
gi|9624998 heterogeneous nuclear ribonucleoprotein H2 [Homo sapi... 391 e-109
gi|148470406 heterogeneous nuclear ribonucleoprotein F [Homo sap... 340 1e-93
gi|148470404 heterogeneous nuclear ribonucleoprotein F [Homo sap... 340 1e-93
gi|148470402 heterogeneous nuclear ribonucleoprotein F [Homo sap... 340 1e-93
gi|148470400 heterogeneous nuclear ribonucleoprotein F [Homo sap... 340 1e-93
gi|148470397 heterogeneous nuclear ribonucleoprotein F [Homo sap... 340 1e-93
gi|4826760 heterogeneous nuclear ribonucleoprotein F [Homo sapiens] 340 1e-93
gi|149193321 G-rich RNA sequence binding factor 1 isoform 1 [Hom... 115 4e-26
gi|149193319 G-rich RNA sequence binding factor 1 isoform 2 [Hom... 115 4e-26
gi|118722349 RNA binding motif protein 12B [Homo sapiens] 77 2e-14
gi|170763533 RNA binding motif protein 35A isoform 5 [Homo sapiens] 76 4e-14
gi|170763529 RNA binding motif protein 35A isoform 3 [Homo sapiens] 76 4e-14
gi|170763527 RNA binding motif protein 35A isoform 4 [Homo sapiens] 76 4e-14
gi|170763525 RNA binding motif protein 35A isoform 2 [Homo sapiens] 76 4e-14
gi|56790297 RNA binding motif protein 35A isoform 1 [Homo sapiens] 76 4e-14
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 74 1e-13
gi|45935393 RNA binding motif protein 35B [Homo sapiens] 74 2e-13
gi|19923345 RNA binding motif protein 12 [Homo sapiens] 72 7e-13
gi|23510462 RNA binding motif protein 12 [Homo sapiens] 72 7e-13
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 70 3e-12
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 70 3e-12
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 65 8e-11
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 65 8e-11
gi|55956899 keratin 9 [Homo sapiens] 63 3e-10
gi|109255251 loricrin [Homo sapiens] 62 5e-10
gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi... 62 9e-10
>gi|14141159 heterogeneous nuclear ribonucleoprotein H3 isoform b
[Homo sapiens]
Length = 331
Score = 709 bits (1830), Expect = 0.0
Identities = 331/331 (100%), Positives = 331/331 (100%)
Query: 1 MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEA 60
MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEA
Sbjct: 1 MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEA 60
Query: 61 FVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGG 120
FVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGG
Sbjct: 61 FVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGG 120
Query: 121 RGGYYGAGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGH 180
RGGYYGAGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGH
Sbjct: 121 RGGYYGAGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGH 180
Query: 181 FVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDK 240
FVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDK
Sbjct: 181 FVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDK 240
Query: 241 NNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTP 300
NNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTP
Sbjct: 241 NNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTP 300
Query: 301 DGLGGYGRGGGGSGGYYGQGGMSGGGWRGMY 331
DGLGGYGRGGGGSGGYYGQGGMSGGGWRGMY
Sbjct: 301 DGLGGYGRGGGGSGGYYGQGGMSGGGWRGMY 331
>gi|14141157 heterogeneous nuclear ribonucleoprotein H3 isoform a
[Homo sapiens]
Length = 346
Score = 699 bits (1804), Expect = 0.0
Identities = 331/346 (95%), Positives = 331/346 (95%), Gaps = 15/346 (4%)
Query: 1 MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEA 60
MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEA
Sbjct: 1 MDWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEA 60
Query: 61 FVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGG 120
FVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGG
Sbjct: 61 FVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGG 120
Query: 121 RGGYYGAGRGS---------------YGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHG 165
RGGYYGAGRGS YGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHG
Sbjct: 121 RGGYYGAGRGSMYDRMRRGGDGYDGGYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHG 180
Query: 166 YGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVE 225
YGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVE
Sbjct: 181 YGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVE 240
Query: 226 FVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVG 285
FVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVG
Sbjct: 241 FVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVG 300
Query: 286 RMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGGGWRGMY 331
RMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGGGWRGMY
Sbjct: 301 RMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGGGWRGMY 346
>gi|5031753 heterogeneous nuclear ribonucleoprotein H1 [Homo
sapiens]
Length = 449
Score = 392 bits (1006), Expect = e-109
Identities = 209/343 (60%), Positives = 233/343 (67%), Gaps = 39/343 (11%)
Query: 1 MDWVMKHNGPND---ASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRST 57
MDWV+KH GPN A+DG VRLRGLPFGCSKEEIVQFF GLEIVPNGITL +D+QGRST
Sbjct: 93 MDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRST 152
Query: 58 GEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLG-QRPGPYDR 116
GEAFVQFAS+EIAE AL KHKERIGHRYIEIF+SSR+E++ YDPPR+L+ QRPGPYDR
Sbjct: 153 GEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDR 212
Query: 117 PIGGRGGYYGAGRGS-------------YGGFDDYGGYNN-YGYGNDGFD-DRMRDGRGM 161
P GR GY GRG+ YGG+DDY GYN+ YG+G+D F D GM
Sbjct: 213 PGAGR-GYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGM 271
Query: 162 GGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGE 221
H YG G GH VHMRGLP+RATENDI NFFSPLNP+RVHI+IG DGR TGE
Sbjct: 272 SDHRYGDGGSTFQS-TTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGE 330
Query: 222 ADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSG-------------MGGSGMG 268
ADVEF THEDAVAAMSKDK NMQHRY+ELFLNST G G G+ G
Sbjct: 331 ADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGG 390
Query: 269 GYGRD-----GMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGY 306
YG G+ NQ YG + Y GGYG + GY
Sbjct: 391 AYGSQMMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGY 433
Score = 75.1 bits (183), Expect = 8e-14
Identities = 84/323 (26%), Positives = 119/323 (36%), Gaps = 98/323 (30%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
V++RGLP+ CS +E+ +FF +I GI +GR +
Sbjct: 13 VKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPS------------------ 54
Query: 76 KHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSYGGF 135
G ++E+ S E+K R +G R Y + +
Sbjct: 55 ------GEAFVEL--ESEDEVKLALKKDRETMGHR-------------YVEVFKSNNVEM 93
Query: 136 D---DYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRGLPFRAT 192
D + G N+ NDGF V +RGLPF +
Sbjct: 94 DWVLKHTGPNSPDTANDGF------------------------------VRLRGLPFGCS 123
Query: 193 ENDIANFFSPLN--PIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQHRYIEL 250
+ +I FFS L P + + + GR+TGEA V+F + E A A+ K K + HRYIE+
Sbjct: 124 KEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEI 183
Query: 251 FLNSTPGGGSG-------MGGSGMGGYGRDGMDNQGGYGSVGR-MGMGNNYSGGYGTPDG 302
F +S + M G Y R G GY S+GR G G YG
Sbjct: 184 FKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGR--GYNSIGRGAGFERMRRGAYG---- 237
Query: 303 LGGYGRGGGGSGGYYGQGGMSGG 325
GG GGY G + G
Sbjct: 238 --------GGYGGYDDYNGYNDG 252
Score = 48.9 bits (115), Expect = 6e-06
Identities = 25/77 (32%), Positives = 41/77 (53%), Gaps = 4/77 (5%)
Query: 179 GHFVHMRGLPFRATENDIANFFSPLNPIR----VHIDIGADGRATGEADVEFVTHEDAVA 234
G V +RGLP+ + +++ FFS + +GR +GEA VE + ++
Sbjct: 10 GFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKL 69
Query: 235 AMSKDKNNMQHRYIELF 251
A+ KD+ M HRY+E+F
Sbjct: 70 ALKKDRETMGHRYVEVF 86
>gi|74099697 heterogeneous nuclear ribonucleoprotein H2 [Homo
sapiens]
Length = 449
Score = 391 bits (1004), Expect = e-109
Identities = 210/345 (60%), Positives = 236/345 (68%), Gaps = 43/345 (12%)
Query: 1 MDWVMKHNGPND---ASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRST 57
MDWV+KH GPN A+DG VRLRGLPFGCSKEEIVQFF GLEIVPNG+TL +D+QGRST
Sbjct: 93 MDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRST 152
Query: 58 GEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLG-QRPGPYDR 116
GEAFVQFAS+EIAE AL KHKERIGHRYIEIF+SSR+E++ YDPPR+L+ QRPGPYDR
Sbjct: 153 GEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDR 212
Query: 117 PIGGRGGYYGAGRGS-------------YGGFDDYGGYNN-YGYGNDGFD-DRMRDGRGM 161
P GR GY GRG+ YGG+DDYGGYN+ YG+G+D F D GM
Sbjct: 213 PGAGR-GYNSIGRGAGFERMRRGAYGGGYGGYDDYGGYNDGYGFGSDRFGRDLNYCFSGM 271
Query: 162 GGHGYGGAGDASSGFHG--GHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRAT 219
H Y GD S F GH VHMRGLP+RATENDI NFFSPLNP+RVHI+IG DGR T
Sbjct: 272 SDHRY---GDGGSSFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVT 328
Query: 220 GEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSG-------------MGGSG 266
GEADVEF THEDAVAAM+KDK NMQHRY+ELFLNST G G G+
Sbjct: 329 GEADVEFATHEDAVAAMAKDKANMQHRYVELFLNSTAGTSGGAYDHSYVELFLNSTAGAS 388
Query: 267 MGGYGRD-----GMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGY 306
G YG G+ NQ YG + Y GGYG + GY
Sbjct: 389 GGAYGSQMMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGY 433
Score = 78.2 bits (191), Expect = 1e-14
Identities = 85/323 (26%), Positives = 122/323 (37%), Gaps = 98/323 (30%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
V++RGLP+ CS +E+++FF +I +GI +GR +
Sbjct: 13 VKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPS------------------ 54
Query: 76 KHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSYGGF 135
G ++E+ S E+K R +G R Y + +
Sbjct: 55 ------GEAFVEL--ESEEEVKLALKKDRETMGHR-------------YVEVFKSNSVEM 93
Query: 136 D---DYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRGLPFRAT 192
D + G N+ NDGF V +RGLPF +
Sbjct: 94 DWVLKHTGPNSPDTANDGF------------------------------VRLRGLPFGCS 123
Query: 193 ENDIANFFSPLN--PIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQHRYIEL 250
+ +I FFS L P + + + GR+TGEA V+F + E A A+ K K + HRYIE+
Sbjct: 124 KEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEI 183
Query: 251 FLNSTPGGGSG-------MGGSGMGGYGRDGMDNQGGYGSVGR-MGMGNNYSGGYGTPDG 302
F +S + M G Y R G GY S+GR G G YG
Sbjct: 184 FKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGR--GYNSIGRGAGFERMRRGAYG---- 237
Query: 303 LGGYGRGGGGSGGYYGQGGMSGG 325
GG GGY GG + G
Sbjct: 238 --------GGYGGYDDYGGYNDG 252
Score = 50.8 bits (120), Expect = 2e-06
Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 4/81 (4%)
Query: 179 GHFVHMRGLPFRATENDIANFFSPLN----PIRVHIDIGADGRATGEADVEFVTHEDAVA 234
G V +RGLP+ + +++ FFS + +GR +GEA VE + E+
Sbjct: 10 GFVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKL 69
Query: 235 AMSKDKNNMQHRYIELFLNST 255
A+ KD+ M HRY+E+F +++
Sbjct: 70 ALKKDRETMGHRYVEVFKSNS 90
>gi|9624998 heterogeneous nuclear ribonucleoprotein H2 [Homo
sapiens]
Length = 449
Score = 391 bits (1004), Expect = e-109
Identities = 210/345 (60%), Positives = 236/345 (68%), Gaps = 43/345 (12%)
Query: 1 MDWVMKHNGPND---ASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRST 57
MDWV+KH GPN A+DG VRLRGLPFGCSKEEIVQFF GLEIVPNG+TL +D+QGRST
Sbjct: 93 MDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRST 152
Query: 58 GEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLG-QRPGPYDR 116
GEAFVQFAS+EIAE AL KHKERIGHRYIEIF+SSR+E++ YDPPR+L+ QRPGPYDR
Sbjct: 153 GEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDR 212
Query: 117 PIGGRGGYYGAGRGS-------------YGGFDDYGGYNN-YGYGNDGFD-DRMRDGRGM 161
P GR GY GRG+ YGG+DDYGGYN+ YG+G+D F D GM
Sbjct: 213 PGAGR-GYNSIGRGAGFERMRRGAYGGGYGGYDDYGGYNDGYGFGSDRFGRDLNYCFSGM 271
Query: 162 GGHGYGGAGDASSGFHG--GHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRAT 219
H Y GD S F GH VHMRGLP+RATENDI NFFSPLNP+RVHI+IG DGR T
Sbjct: 272 SDHRY---GDGGSSFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVT 328
Query: 220 GEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSG-------------MGGSG 266
GEADVEF THEDAVAAM+KDK NMQHRY+ELFLNST G G G+
Sbjct: 329 GEADVEFATHEDAVAAMAKDKANMQHRYVELFLNSTAGTSGGAYDHSYVELFLNSTAGAS 388
Query: 267 MGGYGRD-----GMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGY 306
G YG G+ NQ YG + Y GGYG + GY
Sbjct: 389 GGAYGSQMMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGY 433
Score = 78.2 bits (191), Expect = 1e-14
Identities = 85/323 (26%), Positives = 122/323 (37%), Gaps = 98/323 (30%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
V++RGLP+ CS +E+++FF +I +GI +GR +
Sbjct: 13 VKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPS------------------ 54
Query: 76 KHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSYGGF 135
G ++E+ S E+K R +G R Y + +
Sbjct: 55 ------GEAFVEL--ESEEEVKLALKKDRETMGHR-------------YVEVFKSNSVEM 93
Query: 136 D---DYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRGLPFRAT 192
D + G N+ NDGF V +RGLPF +
Sbjct: 94 DWVLKHTGPNSPDTANDGF------------------------------VRLRGLPFGCS 123
Query: 193 ENDIANFFSPLN--PIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQHRYIEL 250
+ +I FFS L P + + + GR+TGEA V+F + E A A+ K K + HRYIE+
Sbjct: 124 KEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEI 183
Query: 251 FLNSTPGGGSG-------MGGSGMGGYGRDGMDNQGGYGSVGR-MGMGNNYSGGYGTPDG 302
F +S + M G Y R G GY S+GR G G YG
Sbjct: 184 FKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGR--GYNSIGRGAGFERMRRGAYG---- 237
Query: 303 LGGYGRGGGGSGGYYGQGGMSGG 325
GG GGY GG + G
Sbjct: 238 --------GGYGGYDDYGGYNDG 252
Score = 50.8 bits (120), Expect = 2e-06
Identities = 26/81 (32%), Positives = 44/81 (54%), Gaps = 4/81 (4%)
Query: 179 GHFVHMRGLPFRATENDIANFFSPLN----PIRVHIDIGADGRATGEADVEFVTHEDAVA 234
G V +RGLP+ + +++ FFS + +GR +GEA VE + E+
Sbjct: 10 GFVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKL 69
Query: 235 AMSKDKNNMQHRYIELFLNST 255
A+ KD+ M HRY+E+F +++
Sbjct: 70 ALKKDRETMGHRYVEVFKSNS 90
>gi|148470406 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 340 bits (872), Expect = 1e-93
Identities = 187/328 (57%), Positives = 224/328 (68%), Gaps = 28/328 (8%)
Query: 1 MDWVMKHNGPNDA---SDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRST 57
MDWV+KH+GPN A +DG VRLRGLPFGC+KEEIVQFF GLEIVPNGITL +D +G+ T
Sbjct: 93 MDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKIT 152
Query: 58 GEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLG-QRPGPYDR 116
GEAFVQFAS+E+AE ALGKHKERIGHRYIE+F+SS+ E++ + DPP + + QRPGPYDR
Sbjct: 153 GEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDR 212
Query: 117 P------IG---------GRGGYYGAGRGSYGGFDDYGGYNN-YGYGNDGFD-DRMRDGR 159
P IG R G Y G YGG+++Y G ++ YG+ D F D
Sbjct: 213 PGTARRYIGIVKQAGLERMRPGAYSTG---YGGYEEYSGLSDGYGFTTDLFGRDLSYCLS 269
Query: 160 GMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRAT 219
GM H YG + + + GH VHMRGLP++ATENDI NFFSPLNP+RVHI+IG DGR T
Sbjct: 270 GMYDHRYGDS-EFTVQSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVT 328
Query: 220 GEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSG-MGGYGRDGMDNQ 278
GEADVEF THE+AVAAMSKD+ NMQHRYIELFLNST G +G S M G G Q
Sbjct: 329 GEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAA--Q 386
Query: 279 GGYGSVGRMGMGNNYSGGYGTPDGLGGY 306
Y + + Y GY + +GGY
Sbjct: 387 ATYSGLESQSVSGCYGAGYSGQNSMGGY 414
Score = 113 bits (282), Expect = 3e-25
Identities = 94/319 (29%), Positives = 130/319 (40%), Gaps = 80/319 (25%)
Query: 9 GPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPN--GITLTMDYQGRSTGEAFVQFAS 66
GP V+LRGLP+ CS E++ F I G+ +GR +GEAFV+ S
Sbjct: 4 GPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGS 63
Query: 67 KEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYG 126
++ + AL K +E +GHRYIE+F+S R+E+
Sbjct: 64 EDDVKMALKKDRESMGHRYIEVFKSHRTEMDWVL-------------------------- 97
Query: 127 AGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRG 186
+ G N+ NDGF V +RG
Sbjct: 98 ----------KHSGPNSADSANDGF------------------------------VRLRG 117
Query: 187 LPFRATENDIANFFSPLN--PIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQ 244
LPF T+ +I FFS L P + + + +G+ TGEA V+F + E A A+ K K +
Sbjct: 118 LPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIG 177
Query: 245 HRYIELFLNSTPGGGS-------GMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGY 297
HRYIE+F +S S M G Y R G + G V + G+ G Y
Sbjct: 178 HRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARR-YIGIVKQAGLERMRPGAY 236
Query: 298 GTPDGLGGYGRGGGGSGGY 316
T G GGY G S GY
Sbjct: 237 ST--GYGGYEEYSGLSDGY 253
>gi|148470404 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 340 bits (872), Expect = 1e-93
Identities = 187/328 (57%), Positives = 224/328 (68%), Gaps = 28/328 (8%)
Query: 1 MDWVMKHNGPNDA---SDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRST 57
MDWV+KH+GPN A +DG VRLRGLPFGC+KEEIVQFF GLEIVPNGITL +D +G+ T
Sbjct: 93 MDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKIT 152
Query: 58 GEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLG-QRPGPYDR 116
GEAFVQFAS+E+AE ALGKHKERIGHRYIE+F+SS+ E++ + DPP + + QRPGPYDR
Sbjct: 153 GEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDR 212
Query: 117 P------IG---------GRGGYYGAGRGSYGGFDDYGGYNN-YGYGNDGFD-DRMRDGR 159
P IG R G Y G YGG+++Y G ++ YG+ D F D
Sbjct: 213 PGTARRYIGIVKQAGLERMRPGAYSTG---YGGYEEYSGLSDGYGFTTDLFGRDLSYCLS 269
Query: 160 GMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRAT 219
GM H YG + + + GH VHMRGLP++ATENDI NFFSPLNP+RVHI+IG DGR T
Sbjct: 270 GMYDHRYGDS-EFTVQSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVT 328
Query: 220 GEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSG-MGGYGRDGMDNQ 278
GEADVEF THE+AVAAMSKD+ NMQHRYIELFLNST G +G S M G G Q
Sbjct: 329 GEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAA--Q 386
Query: 279 GGYGSVGRMGMGNNYSGGYGTPDGLGGY 306
Y + + Y GY + +GGY
Sbjct: 387 ATYSGLESQSVSGCYGAGYSGQNSMGGY 414
Score = 113 bits (282), Expect = 3e-25
Identities = 94/319 (29%), Positives = 130/319 (40%), Gaps = 80/319 (25%)
Query: 9 GPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPN--GITLTMDYQGRSTGEAFVQFAS 66
GP V+LRGLP+ CS E++ F I G+ +GR +GEAFV+ S
Sbjct: 4 GPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGS 63
Query: 67 KEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYG 126
++ + AL K +E +GHRYIE+F+S R+E+
Sbjct: 64 EDDVKMALKKDRESMGHRYIEVFKSHRTEMDWVL-------------------------- 97
Query: 127 AGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRG 186
+ G N+ NDGF V +RG
Sbjct: 98 ----------KHSGPNSADSANDGF------------------------------VRLRG 117
Query: 187 LPFRATENDIANFFSPLN--PIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQ 244
LPF T+ +I FFS L P + + + +G+ TGEA V+F + E A A+ K K +
Sbjct: 118 LPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIG 177
Query: 245 HRYIELFLNSTPGGGS-------GMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGY 297
HRYIE+F +S S M G Y R G + G V + G+ G Y
Sbjct: 178 HRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARR-YIGIVKQAGLERMRPGAY 236
Query: 298 GTPDGLGGYGRGGGGSGGY 316
T G GGY G S GY
Sbjct: 237 ST--GYGGYEEYSGLSDGY 253
>gi|148470402 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 340 bits (872), Expect = 1e-93
Identities = 187/328 (57%), Positives = 224/328 (68%), Gaps = 28/328 (8%)
Query: 1 MDWVMKHNGPNDA---SDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRST 57
MDWV+KH+GPN A +DG VRLRGLPFGC+KEEIVQFF GLEIVPNGITL +D +G+ T
Sbjct: 93 MDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKIT 152
Query: 58 GEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLG-QRPGPYDR 116
GEAFVQFAS+E+AE ALGKHKERIGHRYIE+F+SS+ E++ + DPP + + QRPGPYDR
Sbjct: 153 GEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDR 212
Query: 117 P------IG---------GRGGYYGAGRGSYGGFDDYGGYNN-YGYGNDGFD-DRMRDGR 159
P IG R G Y G YGG+++Y G ++ YG+ D F D
Sbjct: 213 PGTARRYIGIVKQAGLERMRPGAYSTG---YGGYEEYSGLSDGYGFTTDLFGRDLSYCLS 269
Query: 160 GMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRAT 219
GM H YG + + + GH VHMRGLP++ATENDI NFFSPLNP+RVHI+IG DGR T
Sbjct: 270 GMYDHRYGDS-EFTVQSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVT 328
Query: 220 GEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSG-MGGYGRDGMDNQ 278
GEADVEF THE+AVAAMSKD+ NMQHRYIELFLNST G +G S M G G Q
Sbjct: 329 GEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAA--Q 386
Query: 279 GGYGSVGRMGMGNNYSGGYGTPDGLGGY 306
Y + + Y GY + +GGY
Sbjct: 387 ATYSGLESQSVSGCYGAGYSGQNSMGGY 414
Score = 113 bits (282), Expect = 3e-25
Identities = 94/319 (29%), Positives = 130/319 (40%), Gaps = 80/319 (25%)
Query: 9 GPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPN--GITLTMDYQGRSTGEAFVQFAS 66
GP V+LRGLP+ CS E++ F I G+ +GR +GEAFV+ S
Sbjct: 4 GPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGS 63
Query: 67 KEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYG 126
++ + AL K +E +GHRYIE+F+S R+E+
Sbjct: 64 EDDVKMALKKDRESMGHRYIEVFKSHRTEMDWVL-------------------------- 97
Query: 127 AGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRG 186
+ G N+ NDGF V +RG
Sbjct: 98 ----------KHSGPNSADSANDGF------------------------------VRLRG 117
Query: 187 LPFRATENDIANFFSPLN--PIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQ 244
LPF T+ +I FFS L P + + + +G+ TGEA V+F + E A A+ K K +
Sbjct: 118 LPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIG 177
Query: 245 HRYIELFLNSTPGGGS-------GMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGY 297
HRYIE+F +S S M G Y R G + G V + G+ G Y
Sbjct: 178 HRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARR-YIGIVKQAGLERMRPGAY 236
Query: 298 GTPDGLGGYGRGGGGSGGY 316
T G GGY G S GY
Sbjct: 237 ST--GYGGYEEYSGLSDGY 253
>gi|148470400 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 340 bits (872), Expect = 1e-93
Identities = 187/328 (57%), Positives = 224/328 (68%), Gaps = 28/328 (8%)
Query: 1 MDWVMKHNGPNDA---SDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRST 57
MDWV+KH+GPN A +DG VRLRGLPFGC+KEEIVQFF GLEIVPNGITL +D +G+ T
Sbjct: 93 MDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKIT 152
Query: 58 GEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLG-QRPGPYDR 116
GEAFVQFAS+E+AE ALGKHKERIGHRYIE+F+SS+ E++ + DPP + + QRPGPYDR
Sbjct: 153 GEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDR 212
Query: 117 P------IG---------GRGGYYGAGRGSYGGFDDYGGYNN-YGYGNDGFD-DRMRDGR 159
P IG R G Y G YGG+++Y G ++ YG+ D F D
Sbjct: 213 PGTARRYIGIVKQAGLERMRPGAYSTG---YGGYEEYSGLSDGYGFTTDLFGRDLSYCLS 269
Query: 160 GMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRAT 219
GM H YG + + + GH VHMRGLP++ATENDI NFFSPLNP+RVHI+IG DGR T
Sbjct: 270 GMYDHRYGDS-EFTVQSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVT 328
Query: 220 GEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSG-MGGYGRDGMDNQ 278
GEADVEF THE+AVAAMSKD+ NMQHRYIELFLNST G +G S M G G Q
Sbjct: 329 GEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAA--Q 386
Query: 279 GGYGSVGRMGMGNNYSGGYGTPDGLGGY 306
Y + + Y GY + +GGY
Sbjct: 387 ATYSGLESQSVSGCYGAGYSGQNSMGGY 414
Score = 113 bits (282), Expect = 3e-25
Identities = 94/319 (29%), Positives = 130/319 (40%), Gaps = 80/319 (25%)
Query: 9 GPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPN--GITLTMDYQGRSTGEAFVQFAS 66
GP V+LRGLP+ CS E++ F I G+ +GR +GEAFV+ S
Sbjct: 4 GPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGS 63
Query: 67 KEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYG 126
++ + AL K +E +GHRYIE+F+S R+E+
Sbjct: 64 EDDVKMALKKDRESMGHRYIEVFKSHRTEMDWVL-------------------------- 97
Query: 127 AGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRG 186
+ G N+ NDGF V +RG
Sbjct: 98 ----------KHSGPNSADSANDGF------------------------------VRLRG 117
Query: 187 LPFRATENDIANFFSPLN--PIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQ 244
LPF T+ +I FFS L P + + + +G+ TGEA V+F + E A A+ K K +
Sbjct: 118 LPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIG 177
Query: 245 HRYIELFLNSTPGGGS-------GMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGY 297
HRYIE+F +S S M G Y R G + G V + G+ G Y
Sbjct: 178 HRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARR-YIGIVKQAGLERMRPGAY 236
Query: 298 GTPDGLGGYGRGGGGSGGY 316
T G GGY G S GY
Sbjct: 237 ST--GYGGYEEYSGLSDGY 253
>gi|148470397 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 340 bits (872), Expect = 1e-93
Identities = 187/328 (57%), Positives = 224/328 (68%), Gaps = 28/328 (8%)
Query: 1 MDWVMKHNGPNDA---SDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRST 57
MDWV+KH+GPN A +DG VRLRGLPFGC+KEEIVQFF GLEIVPNGITL +D +G+ T
Sbjct: 93 MDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKIT 152
Query: 58 GEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLG-QRPGPYDR 116
GEAFVQFAS+E+AE ALGKHKERIGHRYIE+F+SS+ E++ + DPP + + QRPGPYDR
Sbjct: 153 GEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDR 212
Query: 117 P------IG---------GRGGYYGAGRGSYGGFDDYGGYNN-YGYGNDGFD-DRMRDGR 159
P IG R G Y G YGG+++Y G ++ YG+ D F D
Sbjct: 213 PGTARRYIGIVKQAGLERMRPGAYSTG---YGGYEEYSGLSDGYGFTTDLFGRDLSYCLS 269
Query: 160 GMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRAT 219
GM H YG + + + GH VHMRGLP++ATENDI NFFSPLNP+RVHI+IG DGR T
Sbjct: 270 GMYDHRYGDS-EFTVQSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVT 328
Query: 220 GEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSG-MGGYGRDGMDNQ 278
GEADVEF THE+AVAAMSKD+ NMQHRYIELFLNST G +G S M G G Q
Sbjct: 329 GEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAA--Q 386
Query: 279 GGYGSVGRMGMGNNYSGGYGTPDGLGGY 306
Y + + Y GY + +GGY
Sbjct: 387 ATYSGLESQSVSGCYGAGYSGQNSMGGY 414
Score = 113 bits (282), Expect = 3e-25
Identities = 94/319 (29%), Positives = 130/319 (40%), Gaps = 80/319 (25%)
Query: 9 GPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPN--GITLTMDYQGRSTGEAFVQFAS 66
GP V+LRGLP+ CS E++ F I G+ +GR +GEAFV+ S
Sbjct: 4 GPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGS 63
Query: 67 KEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYG 126
++ + AL K +E +GHRYIE+F+S R+E+
Sbjct: 64 EDDVKMALKKDRESMGHRYIEVFKSHRTEMDWVL-------------------------- 97
Query: 127 AGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRG 186
+ G N+ NDGF V +RG
Sbjct: 98 ----------KHSGPNSADSANDGF------------------------------VRLRG 117
Query: 187 LPFRATENDIANFFSPLN--PIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQ 244
LPF T+ +I FFS L P + + + +G+ TGEA V+F + E A A+ K K +
Sbjct: 118 LPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIG 177
Query: 245 HRYIELFLNSTPGGGS-------GMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGY 297
HRYIE+F +S S M G Y R G + G V + G+ G Y
Sbjct: 178 HRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARR-YIGIVKQAGLERMRPGAY 236
Query: 298 GTPDGLGGYGRGGGGSGGY 316
T G GGY G S GY
Sbjct: 237 ST--GYGGYEEYSGLSDGY 253
>gi|4826760 heterogeneous nuclear ribonucleoprotein F [Homo sapiens]
Length = 415
Score = 340 bits (872), Expect = 1e-93
Identities = 187/328 (57%), Positives = 224/328 (68%), Gaps = 28/328 (8%)
Query: 1 MDWVMKHNGPNDA---SDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRST 57
MDWV+KH+GPN A +DG VRLRGLPFGC+KEEIVQFF GLEIVPNGITL +D +G+ T
Sbjct: 93 MDWVLKHSGPNSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKIT 152
Query: 58 GEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLG-QRPGPYDR 116
GEAFVQFAS+E+AE ALGKHKERIGHRYIE+F+SS+ E++ + DPP + + QRPGPYDR
Sbjct: 153 GEAFVQFASQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDR 212
Query: 117 P------IG---------GRGGYYGAGRGSYGGFDDYGGYNN-YGYGNDGFD-DRMRDGR 159
P IG R G Y G YGG+++Y G ++ YG+ D F D
Sbjct: 213 PGTARRYIGIVKQAGLERMRPGAYSTG---YGGYEEYSGLSDGYGFTTDLFGRDLSYCLS 269
Query: 160 GMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRAT 219
GM H YG + + + GH VHMRGLP++ATENDI NFFSPLNP+RVHI+IG DGR T
Sbjct: 270 GMYDHRYGDS-EFTVQSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVT 328
Query: 220 GEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSG-MGGYGRDGMDNQ 278
GEADVEF THE+AVAAMSKD+ NMQHRYIELFLNST G +G S M G G Q
Sbjct: 329 GEADVEFATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAA--Q 386
Query: 279 GGYGSVGRMGMGNNYSGGYGTPDGLGGY 306
Y + + Y GY + +GGY
Sbjct: 387 ATYSGLESQSVSGCYGAGYSGQNSMGGY 414
Score = 113 bits (282), Expect = 3e-25
Identities = 94/319 (29%), Positives = 130/319 (40%), Gaps = 80/319 (25%)
Query: 9 GPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPN--GITLTMDYQGRSTGEAFVQFAS 66
GP V+LRGLP+ CS E++ F I G+ +GR +GEAFV+ S
Sbjct: 4 GPEGGEGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGS 63
Query: 67 KEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYG 126
++ + AL K +E +GHRYIE+F+S R+E+
Sbjct: 64 EDDVKMALKKDRESMGHRYIEVFKSHRTEMDWVL-------------------------- 97
Query: 127 AGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRG 186
+ G N+ NDGF V +RG
Sbjct: 98 ----------KHSGPNSADSANDGF------------------------------VRLRG 117
Query: 187 LPFRATENDIANFFSPLN--PIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQ 244
LPF T+ +I FFS L P + + + +G+ TGEA V+F + E A A+ K K +
Sbjct: 118 LPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKERIG 177
Query: 245 HRYIELFLNSTPGGGS-------GMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGY 297
HRYIE+F +S S M G Y R G + G V + G+ G Y
Sbjct: 178 HRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARR-YIGIVKQAGLERMRPGAY 236
Query: 298 GTPDGLGGYGRGGGGSGGY 316
T G GGY G S GY
Sbjct: 237 ST--GYGGYEEYSGLSDGY 253
>gi|149193321 G-rich RNA sequence binding factor 1 isoform 1 [Homo
sapiens]
Length = 480
Score = 115 bits (289), Expect = 4e-26
Identities = 52/79 (65%), Positives = 64/79 (81%)
Query: 180 HFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKD 239
HFVHMRGLPF+A DI NFF+PL P+R+ ++ + G+ATGEADV F THEDAVAAM KD
Sbjct: 401 HFVHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKD 460
Query: 240 KNNMQHRYIELFLNSTPGG 258
++++ HRYIELFLNS P G
Sbjct: 461 RSHVHHRYIELFLNSCPKG 479
Score = 98.6 bits (244), Expect = 7e-21
Identities = 50/85 (58%), Positives = 64/85 (75%), Gaps = 3/85 (3%)
Query: 14 SDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGR-STGEAFVQFASKEIAEN 72
+DG VRLRGLP+ C++++IV FF GL IV IT MDY+GR TGEA+VQF E+A
Sbjct: 248 NDGVVRLRGLPYSCNEKDIVDFFAGLNIVD--ITFVMDYRGRRKTGEAYVQFEEPEMANQ 305
Query: 73 ALGKHKERIGHRYIEIFRSSRSEIK 97
AL KH+E IG+RYIEIF S R+E++
Sbjct: 306 ALLKHREEIGNRYIEIFPSRRNEVR 330
Score = 58.2 bits (139), Expect = 1e-08
Identities = 24/81 (29%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
+R +GLP+ C+ E+++ FF I NGI ++ G+ G+A ++ S++ + AL
Sbjct: 152 IRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALE 211
Query: 76 KHKERIGHRYIEIFRSSRSEI 96
KH+ +G RY+E++ + ++
Sbjct: 212 KHRMYMGQRYVEVYEINNEDV 232
Score = 58.2 bits (139), Expect = 1e-08
Identities = 31/75 (41%), Positives = 46/75 (61%), Gaps = 2/75 (2%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
V +RGLPF + ++I+ FF L+ P IT+ G++TGEA V F + E A A+ K
Sbjct: 403 VHMRGLPFQANAQDIINFFAPLK--PVRITMEYSSSGKATGEADVHFETHEDAVAAMLKD 460
Query: 78 KERIGHRYIEIFRSS 92
+ + HRYIE+F +S
Sbjct: 461 RSHVHHRYIELFLNS 475
Score = 45.8 bits (107), Expect = 5e-05
Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Query: 182 VHMRGLPFRATENDIANFFSPLNPIR-----VHIDIGADGRATGEADVEFVTHEDAVAAM 236
+ +GLP+ T D+ NFFS IR +H + DG+ G+A +E + +D A+
Sbjct: 152 IRAQGLPWSCTMEDVLNFFSDCR-IRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKAL 210
Query: 237 SKDKNNMQHRYIELF 251
K + M RY+E++
Sbjct: 211 EKHRMYMGQRYVEVY 225
>gi|149193319 G-rich RNA sequence binding factor 1 isoform 2 [Homo
sapiens]
Length = 318
Score = 115 bits (289), Expect = 4e-26
Identities = 52/79 (65%), Positives = 64/79 (81%)
Query: 180 HFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKD 239
HFVHMRGLPF+A DI NFF+PL P+R+ ++ + G+ATGEADV F THEDAVAAM KD
Sbjct: 239 HFVHMRGLPFQANAQDIINFFAPLKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKD 298
Query: 240 KNNMQHRYIELFLNSTPGG 258
++++ HRYIELFLNS P G
Sbjct: 299 RSHVHHRYIELFLNSCPKG 317
Score = 98.6 bits (244), Expect = 7e-21
Identities = 50/85 (58%), Positives = 64/85 (75%), Gaps = 3/85 (3%)
Query: 14 SDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGR-STGEAFVQFASKEIAEN 72
+DG VRLRGLP+ C++++IV FF GL IV IT MDY+GR TGEA+VQF E+A
Sbjct: 86 NDGVVRLRGLPYSCNEKDIVDFFAGLNIVD--ITFVMDYRGRRKTGEAYVQFEEPEMANQ 143
Query: 73 ALGKHKERIGHRYIEIFRSSRSEIK 97
AL KH+E IG+RYIEIF S R+E++
Sbjct: 144 ALLKHREEIGNRYIEIFPSRRNEVR 168
Score = 58.2 bits (139), Expect = 1e-08
Identities = 31/75 (41%), Positives = 46/75 (61%), Gaps = 2/75 (2%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
V +RGLPF + ++I+ FF L+ P IT+ G++TGEA V F + E A A+ K
Sbjct: 241 VHMRGLPFQANAQDIINFFAPLK--PVRITMEYSSSGKATGEADVHFETHEDAVAAMLKD 298
Query: 78 KERIGHRYIEIFRSS 92
+ + HRYIE+F +S
Sbjct: 299 RSHVHHRYIELFLNS 313
Score = 51.6 bits (122), Expect = 1e-06
Identities = 29/71 (40%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 182 VHMRGLPFRATENDIANFFSPLNPIRVHIDIGADG-RATGEADVEFVTHEDAVAAMSKDK 240
V +RGLP+ E DI +FF+ LN + + + G R TGEA V+F E A A+ K +
Sbjct: 90 VRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAYVQFEEPEMANQALLKHR 149
Query: 241 NNMQHRYIELF 251
+ +RYIE+F
Sbjct: 150 EEIGNRYIEIF 160
Score = 44.7 bits (104), Expect = 1e-04
Identities = 19/69 (27%), Positives = 39/69 (56%), Gaps = 2/69 (2%)
Query: 30 EEIVQFFQGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENALGKHKERIGHRYIE 87
E+++ FF I NGI ++ G+ G+A ++ S++ + AL KH+ +G RY+E
Sbjct: 2 EDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQRYVE 61
Query: 88 IFRSSRSEI 96
++ + ++
Sbjct: 62 VYEINNEDV 70
Score = 37.0 bits (84), Expect = 0.024
Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 6/62 (9%)
Query: 195 DIANFFSPLNPIR-----VHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQHRYIE 249
D+ NFFS IR +H + DG+ G+A +E + +D A+ K + M RY+E
Sbjct: 3 DVLNFFSDCR-IRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKALEKHRMYMGQRYVE 61
Query: 250 LF 251
++
Sbjct: 62 VY 63
>gi|118722349 RNA binding motif protein 12B [Homo sapiens]
Length = 1001
Score = 77.0 bits (188), Expect = 2e-14
Identities = 72/239 (30%), Positives = 105/239 (43%), Gaps = 16/239 (6%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
+RL GLPF +I FF GL I G+ + G GEAF+ FA+ E A A+ +
Sbjct: 5 IRLLGLPFIAGPVDIRHFFTGLTIPDGGVHII----GGEIGEAFIIFATDEDARRAISRS 60
Query: 78 KERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSYGGFDD 137
I +E+F SS++E++ + R DR GR G +G S F +
Sbjct: 61 GGFIKDSSVELFLSSKAEMQKTIEMKRT---------DRVGRGRPGSGTSGVDSLSNFIE 111
Query: 138 --YGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATEND 195
+N GYG+ D G GHG ++ +RGLP+ E+D
Sbjct: 112 SVKEEASNSGYGSSINQDAGFHTNGT-GHGNLRPRKTRPLKAENPYLFLRGLPYLVNEDD 170
Query: 196 IANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNS 254
+ FFS L V DGR G+A V+F + DA + ++ M R+IE+ S
Sbjct: 171 VRVFFSGLCVDGVIFLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGS 229
Score = 55.5 bits (132), Expect = 7e-08
Identities = 58/243 (23%), Positives = 96/243 (39%), Gaps = 38/243 (15%)
Query: 10 PNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEI 69
P A + + LRGLP+ +++++ FF GL + +G+ + GR+ G+A V+FAS
Sbjct: 149 PLKAENPYLFLRGLPYLVNEDDVRVFFSGLCV--DGVIFLKHHDGRNNGDAIVKFASCVD 206
Query: 70 AENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGR 129
A L H+ +G R+IE+ + S + F GG G
Sbjct: 207 ASGGLKCHRSFMGSRFIEVMQGSEQQWIEF-------------------GGNAVKEGDVL 247
Query: 130 GSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRGLPF 189
G N+ + R R G+ +VH++ L
Sbjct: 248 RRSEEHSPPRGINDRHFRKRSHSKSPRRTRSRSPLGF--------------YVHLKNLSL 293
Query: 190 RATENDIANFF--SPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNMQHRY 247
E D+ NFF + L ++ + D T A V F T +D A+S K +Q+R
Sbjct: 294 SIDERDLRNFFRGTDLTDEQIRF-LYKDENRTRYAFVMFKTLKDYNTALSLHKTVLQYRP 352
Query: 248 IEL 250
+ +
Sbjct: 353 VHI 355
Score = 43.9 bits (102), Expect = 2e-04
Identities = 22/72 (30%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
+++ LPF + EI+ FF G I+P+ +++ + QG TGEA V + A A+
Sbjct: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAIKDL 986
Query: 78 KER-IGHRYIEI 88
+R +G R +++
Sbjct: 987 NDRPVGPRKVKL 998
Score = 38.9 bits (89), Expect = 0.006
Identities = 24/82 (29%), Positives = 41/82 (50%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
+ +R PF +K E+ +FF + + I L D +G GEA V+F S+E A A +
Sbjct: 402 IYIRNFPFDVTKVEVQKFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKAERLN 461
Query: 78 KERIGHRYIEIFRSSRSEIKGF 99
+ R + + S ++I+ F
Sbjct: 462 RRRFLGTEVLLRLISEAQIQEF 483
Score = 37.7 bits (86), Expect = 0.014
Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 3/63 (4%)
Query: 182 VHMRGLPFRATENDIANFFS--PLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKD 239
+ + LPF+A N+I +FF + P V I G TGEA V + + +A+AA+ KD
Sbjct: 927 IKIMNLPFKANVNEILDFFHGYRIIPDSVSIQYNEQGLPTGEAIVAMINYNEAMAAI-KD 985
Query: 240 KNN 242
N+
Sbjct: 986 LND 988
Score = 34.7 bits (78), Expect = 0.12
Identities = 47/220 (21%), Positives = 82/220 (37%), Gaps = 50/220 (22%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
V L+ L + ++ FF+G ++ I + R T AFV F + + AL H
Sbjct: 286 VHLKNLSLSIDERDLRNFFRGTDLTDEQIRFLYKDENR-TRYAFVMFKTLKDYNTALSLH 344
Query: 78 KERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSYGGFDD 137
K + +R + I SR ++ F R +R G +R D
Sbjct: 345 KTVLQYRPVHIDPISRKQMLKFI---ARYEKKRSGSLER--------------------D 381
Query: 138 YGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIA 197
G+ + Y +G G+ + +++R PF T+ ++
Sbjct: 382 RPGHVSQKYSQEG-----NSGQKL-------------------CIYIRNFPFDVTKVEVQ 417
Query: 198 NFFSP--LNPIRVHIDIGADGRATGEADVEFVTHEDAVAA 235
FF+ L +++ G GEA V+F + E A+ A
Sbjct: 418 KFFADFLLAEDDIYLLYDDKGVGLGEALVKFKSEEQAMKA 457
>gi|170763533 RNA binding motif protein 35A isoform 5 [Homo sapiens]
Length = 604
Score = 76.3 bits (186), Expect = 4e-14
Identities = 42/83 (50%), Positives = 55/83 (66%), Gaps = 3/83 (3%)
Query: 18 VRLRGLPFGCSKEEIVQFF-QGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENAL 74
VR+RGLPF + EE+V FF Q I GI GR TG+AFV FA +E A+NAL
Sbjct: 328 VRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNAL 387
Query: 75 GKHKERIGHRYIEIFRSSRSEIK 97
KHK+ +G RYIE+FRS+ +E++
Sbjct: 388 RKHKDLLGKRYIELFRSTAAEVQ 410
Score = 73.2 bits (178), Expect = 3e-13
Identities = 34/75 (45%), Positives = 51/75 (68%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
VR RGLP+ S ++I +FF+GL I G L ++ QGR GEA V+F S+E + AL +H
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 78 KERIGHRYIEIFRSS 92
K +G RYIE+++++
Sbjct: 287 KHHMGTRYIEVYKAT 301
Score = 58.5 bits (140), Expect = 8e-09
Identities = 30/82 (36%), Positives = 52/82 (63%), Gaps = 3/82 (3%)
Query: 18 VRLRGLPFGCSKEEIVQFFQ--GLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
+RLRGLP+ + E+I+ F +I +G+ + +++QGR +G+AF+Q S + A A
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 76 K-HKERIGHRYIEIFRSSRSEI 96
K HK+ + RY+E+F+ S E+
Sbjct: 507 KCHKKNMKDRYVEVFQCSAEEM 528
Score = 53.9 bits (128), Expect = 2e-07
Identities = 29/72 (40%), Positives = 44/72 (61%), Gaps = 2/72 (2%)
Query: 182 VHMRGLPFRATENDIANFFSPLNPIR--VHIDIGADGRATGEADVEFVTHEDAVAAMSKD 239
V RGLP+++++ DIA FF LN + + + A GR GEA V FV+ E A+ +
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 240 KNNMQHRYIELF 251
K++M RYIE++
Sbjct: 287 KHHMGTRYIEVY 298
Score = 50.1 bits (118), Expect = 3e-06
Identities = 32/75 (42%), Positives = 39/75 (52%), Gaps = 5/75 (6%)
Query: 182 VHMRGLPFRATENDIANFFSPLNPIR-----VHIDIGADGRATGEADVEFVTHEDAVAAM 236
V MRGLPF AT ++ FF PI + DGR TG+A V F E A A+
Sbjct: 328 VRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNAL 387
Query: 237 SKDKNNMQHRYIELF 251
K K+ + RYIELF
Sbjct: 388 RKHKDLLGKRYIELF 402
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 5/75 (6%)
Query: 182 VHMRGLPFRATENDIANFF----SPLNPIRVHIDIGADGRATGEADVEFVTHEDA-VAAM 236
+ +RGLP+ AT DI +F + + VH+ + GR +G+A ++ + + A +AA
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 237 SKDKNNMQHRYIELF 251
K NM+ RY+E+F
Sbjct: 507 KCHKKNMKDRYVEVF 521
>gi|170763529 RNA binding motif protein 35A isoform 3 [Homo sapiens]
Length = 659
Score = 76.3 bits (186), Expect = 4e-14
Identities = 42/83 (50%), Positives = 55/83 (66%), Gaps = 3/83 (3%)
Query: 18 VRLRGLPFGCSKEEIVQFF-QGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENAL 74
VR+RGLPF + EE+V FF Q I GI GR TG+AFV FA +E A+NAL
Sbjct: 328 VRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNAL 387
Query: 75 GKHKERIGHRYIEIFRSSRSEIK 97
KHK+ +G RYIE+FRS+ +E++
Sbjct: 388 RKHKDLLGKRYIELFRSTAAEVQ 410
Score = 73.2 bits (178), Expect = 3e-13
Identities = 34/75 (45%), Positives = 51/75 (68%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
VR RGLP+ S ++I +FF+GL I G L ++ QGR GEA V+F S+E + AL +H
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 78 KERIGHRYIEIFRSS 92
K +G RYIE+++++
Sbjct: 287 KHHMGTRYIEVYKAT 301
Score = 58.5 bits (140), Expect = 8e-09
Identities = 30/82 (36%), Positives = 52/82 (63%), Gaps = 3/82 (3%)
Query: 18 VRLRGLPFGCSKEEIVQFFQ--GLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
+RLRGLP+ + E+I+ F +I +G+ + +++QGR +G+AF+Q S + A A
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 76 K-HKERIGHRYIEIFRSSRSEI 96
K HK+ + RY+E+F+ S E+
Sbjct: 507 KCHKKNMKDRYVEVFQCSAEEM 528
Score = 53.9 bits (128), Expect = 2e-07
Identities = 29/72 (40%), Positives = 44/72 (61%), Gaps = 2/72 (2%)
Query: 182 VHMRGLPFRATENDIANFFSPLNPIR--VHIDIGADGRATGEADVEFVTHEDAVAAMSKD 239
V RGLP+++++ DIA FF LN + + + A GR GEA V FV+ E A+ +
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 240 KNNMQHRYIELF 251
K++M RYIE++
Sbjct: 287 KHHMGTRYIEVY 298
Score = 50.1 bits (118), Expect = 3e-06
Identities = 32/75 (42%), Positives = 39/75 (52%), Gaps = 5/75 (6%)
Query: 182 VHMRGLPFRATENDIANFFSPLNPIR-----VHIDIGADGRATGEADVEFVTHEDAVAAM 236
V MRGLPF AT ++ FF PI + DGR TG+A V F E A A+
Sbjct: 328 VRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNAL 387
Query: 237 SKDKNNMQHRYIELF 251
K K+ + RYIELF
Sbjct: 388 RKHKDLLGKRYIELF 402
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 5/75 (6%)
Query: 182 VHMRGLPFRATENDIANFF----SPLNPIRVHIDIGADGRATGEADVEFVTHEDA-VAAM 236
+ +RGLP+ AT DI +F + + VH+ + GR +G+A ++ + + A +AA
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 237 SKDKNNMQHRYIELF 251
K NM+ RY+E+F
Sbjct: 507 KCHKKNMKDRYVEVF 521
>gi|170763527 RNA binding motif protein 35A isoform 4 [Homo sapiens]
Length = 608
Score = 76.3 bits (186), Expect = 4e-14
Identities = 42/83 (50%), Positives = 55/83 (66%), Gaps = 3/83 (3%)
Query: 18 VRLRGLPFGCSKEEIVQFF-QGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENAL 74
VR+RGLPF + EE+V FF Q I GI GR TG+AFV FA +E A+NAL
Sbjct: 328 VRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNAL 387
Query: 75 GKHKERIGHRYIEIFRSSRSEIK 97
KHK+ +G RYIE+FRS+ +E++
Sbjct: 388 RKHKDLLGKRYIELFRSTAAEVQ 410
Score = 73.2 bits (178), Expect = 3e-13
Identities = 34/75 (45%), Positives = 51/75 (68%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
VR RGLP+ S ++I +FF+GL I G L ++ QGR GEA V+F S+E + AL +H
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 78 KERIGHRYIEIFRSS 92
K +G RYIE+++++
Sbjct: 287 KHHMGTRYIEVYKAT 301
Score = 59.7 bits (143), Expect = 4e-09
Identities = 37/114 (32%), Positives = 60/114 (52%), Gaps = 14/114 (12%)
Query: 18 VRLRGLPFGCSKEEIVQFFQ--GLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
+RLRGLP+ + E+I+ F +I +G+ + +++QGR +G+AF+Q S + A A
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 76 K-HKERIGHRYIEIFRSSRSEI-----------KGFYDPPRRLLGQRPGPYDRP 117
K HK+ + RY+E+F+ S E+ G PP +L P Y P
Sbjct: 507 KCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRNGLSPPPCKLPCLSPPSYTFP 560
Score = 53.9 bits (128), Expect = 2e-07
Identities = 29/72 (40%), Positives = 44/72 (61%), Gaps = 2/72 (2%)
Query: 182 VHMRGLPFRATENDIANFFSPLNPIR--VHIDIGADGRATGEADVEFVTHEDAVAAMSKD 239
V RGLP+++++ DIA FF LN + + + A GR GEA V FV+ E A+ +
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 240 KNNMQHRYIELF 251
K++M RYIE++
Sbjct: 287 KHHMGTRYIEVY 298
Score = 50.1 bits (118), Expect = 3e-06
Identities = 32/75 (42%), Positives = 39/75 (52%), Gaps = 5/75 (6%)
Query: 182 VHMRGLPFRATENDIANFFSPLNPIR-----VHIDIGADGRATGEADVEFVTHEDAVAAM 236
V MRGLPF AT ++ FF PI + DGR TG+A V F E A A+
Sbjct: 328 VRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNAL 387
Query: 237 SKDKNNMQHRYIELF 251
K K+ + RYIELF
Sbjct: 388 RKHKDLLGKRYIELF 402
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 5/75 (6%)
Query: 182 VHMRGLPFRATENDIANFF----SPLNPIRVHIDIGADGRATGEADVEFVTHEDA-VAAM 236
+ +RGLP+ AT DI +F + + VH+ + GR +G+A ++ + + A +AA
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 237 SKDKNNMQHRYIELF 251
K NM+ RY+E+F
Sbjct: 507 KCHKKNMKDRYVEVF 521
>gi|170763525 RNA binding motif protein 35A isoform 2 [Homo sapiens]
Length = 677
Score = 76.3 bits (186), Expect = 4e-14
Identities = 42/83 (50%), Positives = 55/83 (66%), Gaps = 3/83 (3%)
Query: 18 VRLRGLPFGCSKEEIVQFF-QGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENAL 74
VR+RGLPF + EE+V FF Q I GI GR TG+AFV FA +E A+NAL
Sbjct: 328 VRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNAL 387
Query: 75 GKHKERIGHRYIEIFRSSRSEIK 97
KHK+ +G RYIE+FRS+ +E++
Sbjct: 388 RKHKDLLGKRYIELFRSTAAEVQ 410
Score = 73.2 bits (178), Expect = 3e-13
Identities = 34/75 (45%), Positives = 51/75 (68%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
VR RGLP+ S ++I +FF+GL I G L ++ QGR GEA V+F S+E + AL +H
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 78 KERIGHRYIEIFRSS 92
K +G RYIE+++++
Sbjct: 287 KHHMGTRYIEVYKAT 301
Score = 58.5 bits (140), Expect = 8e-09
Identities = 30/82 (36%), Positives = 52/82 (63%), Gaps = 3/82 (3%)
Query: 18 VRLRGLPFGCSKEEIVQFFQ--GLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
+RLRGLP+ + E+I+ F +I +G+ + +++QGR +G+AF+Q S + A A
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 76 K-HKERIGHRYIEIFRSSRSEI 96
K HK+ + RY+E+F+ S E+
Sbjct: 507 KCHKKNMKDRYVEVFQCSAEEM 528
Score = 53.9 bits (128), Expect = 2e-07
Identities = 29/72 (40%), Positives = 44/72 (61%), Gaps = 2/72 (2%)
Query: 182 VHMRGLPFRATENDIANFFSPLNPIR--VHIDIGADGRATGEADVEFVTHEDAVAAMSKD 239
V RGLP+++++ DIA FF LN + + + A GR GEA V FV+ E A+ +
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 240 KNNMQHRYIELF 251
K++M RYIE++
Sbjct: 287 KHHMGTRYIEVY 298
Score = 50.1 bits (118), Expect = 3e-06
Identities = 32/75 (42%), Positives = 39/75 (52%), Gaps = 5/75 (6%)
Query: 182 VHMRGLPFRATENDIANFFSPLNPIR-----VHIDIGADGRATGEADVEFVTHEDAVAAM 236
V MRGLPF AT ++ FF PI + DGR TG+A V F E A A+
Sbjct: 328 VRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNAL 387
Query: 237 SKDKNNMQHRYIELF 251
K K+ + RYIELF
Sbjct: 388 RKHKDLLGKRYIELF 402
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 5/75 (6%)
Query: 182 VHMRGLPFRATENDIANFF----SPLNPIRVHIDIGADGRATGEADVEFVTHEDA-VAAM 236
+ +RGLP+ AT DI +F + + VH+ + GR +G+A ++ + + A +AA
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 237 SKDKNNMQHRYIELF 251
K NM+ RY+E+F
Sbjct: 507 KCHKKNMKDRYVEVF 521
>gi|56790297 RNA binding motif protein 35A isoform 1 [Homo sapiens]
Length = 681
Score = 76.3 bits (186), Expect = 4e-14
Identities = 42/83 (50%), Positives = 55/83 (66%), Gaps = 3/83 (3%)
Query: 18 VRLRGLPFGCSKEEIVQFF-QGLEIV--PNGITLTMDYQGRSTGEAFVQFASKEIAENAL 74
VR+RGLPF + EE+V FF Q I GI GR TG+AFV FA +E A+NAL
Sbjct: 328 VRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNAL 387
Query: 75 GKHKERIGHRYIEIFRSSRSEIK 97
KHK+ +G RYIE+FRS+ +E++
Sbjct: 388 RKHKDLLGKRYIELFRSTAAEVQ 410
Score = 73.2 bits (178), Expect = 3e-13
Identities = 34/75 (45%), Positives = 51/75 (68%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
VR RGLP+ S ++I +FF+GL I G L ++ QGR GEA V+F S+E + AL +H
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 78 KERIGHRYIEIFRSS 92
K +G RYIE+++++
Sbjct: 287 KHHMGTRYIEVYKAT 301
Score = 59.7 bits (143), Expect = 4e-09
Identities = 37/114 (32%), Positives = 60/114 (52%), Gaps = 14/114 (12%)
Query: 18 VRLRGLPFGCSKEEIVQFFQ--GLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
+RLRGLP+ + E+I+ F +I +G+ + +++QGR +G+AF+Q S + A A
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 76 K-HKERIGHRYIEIFRSSRSEI-----------KGFYDPPRRLLGQRPGPYDRP 117
K HK+ + RY+E+F+ S E+ G PP +L P Y P
Sbjct: 507 KCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRNGLSPPPCKLPCLSPPSYTFP 560
Score = 53.9 bits (128), Expect = 2e-07
Identities = 29/72 (40%), Positives = 44/72 (61%), Gaps = 2/72 (2%)
Query: 182 VHMRGLPFRATENDIANFFSPLNPIR--VHIDIGADGRATGEADVEFVTHEDAVAAMSKD 239
V RGLP+++++ DIA FF LN + + + A GR GEA V FV+ E A+ +
Sbjct: 227 VRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRH 286
Query: 240 KNNMQHRYIELF 251
K++M RYIE++
Sbjct: 287 KHHMGTRYIEVY 298
Score = 50.1 bits (118), Expect = 3e-06
Identities = 32/75 (42%), Positives = 39/75 (52%), Gaps = 5/75 (6%)
Query: 182 VHMRGLPFRATENDIANFFSPLNPIR-----VHIDIGADGRATGEADVEFVTHEDAVAAM 236
V MRGLPF AT ++ FF PI + DGR TG+A V F E A A+
Sbjct: 328 VRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNAL 387
Query: 237 SKDKNNMQHRYIELF 251
K K+ + RYIELF
Sbjct: 388 RKHKDLLGKRYIELF 402
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/75 (33%), Positives = 43/75 (57%), Gaps = 5/75 (6%)
Query: 182 VHMRGLPFRATENDIANFF----SPLNPIRVHIDIGADGRATGEADVEFVTHEDA-VAAM 236
+ +RGLP+ AT DI +F + + VH+ + GR +G+A ++ + + A +AA
Sbjct: 447 IRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQ 506
Query: 237 SKDKNNMQHRYIELF 251
K NM+ RY+E+F
Sbjct: 507 KCHKKNMKDRYVEVF 521
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 74.3 bits (181), Expect = 1e-13
Identities = 73/242 (30%), Positives = 95/242 (39%), Gaps = 48/242 (19%)
Query: 112 GPYDRPIGGRGGYYGAGRGSYGGFD-DYGGYNNYGYGNDGFDDRMRDGRG-MGGHGYGGA 169
G DR GRGG G G G GG++ GGY G G R GRG MGG GG
Sbjct: 209 GQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGG------RGGRGGMGGSDRGGF 262
Query: 170 G------------DASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGAD-- 215
D+ + + ++GL T +A++F + I+ + G
Sbjct: 263 NKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMI 322
Query: 216 --------GRATGEADVEFVTHEDAVAAMSK-DKNNMQHRYIELFLNSTPGGGSGMGGSG 266
G+ GEA V F A AA+ D I++ + + GG+G
Sbjct: 323 NLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNG 382
Query: 267 MGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGGG 326
GG GR G +GGYG GG G GG GRGG SGG G G G
Sbjct: 383 RGGRGRGGPMGRGGYG------------GG-----GSGGGGRGGFPSGGGGGGGQQRAGD 425
Query: 327 WR 328
W+
Sbjct: 426 WK 427
Score = 57.8 bits (138), Expect = 1e-08
Identities = 44/104 (42%), Positives = 50/104 (48%), Gaps = 32/104 (30%)
Query: 253 NSTPGGGSGMGGSGMGGYGRD------GMDNQGGYGSVGRMGMGNNYSGGYGTPD----G 302
NS+ GGG G GG G YG+D G + GGYG+ + G G SGGYG D G
Sbjct: 162 NSSSGGGGGGGGGG--NYGQDQSSMSSGGGSGGGYGNQDQSGGGG--SGGYGQQDRGGRG 217
Query: 303 LGGYGRGGGGSGGYY-----------------GQGGMSGGGWRG 329
GG G GGGG GG Y G+GGM GG RG
Sbjct: 218 RGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGM-GGSDRG 260
Score = 51.6 bits (122), Expect = 1e-06
Identities = 83/325 (25%), Positives = 111/325 (34%), Gaps = 93/325 (28%)
Query: 6 KHNGPNDASDG-TVRLRGLPFGCSKEEIVQFFQGLEIVPNG-------ITLTMDYQ-GRS 56
+H+ D SD T+ ++GL + E + +F+ + I+ I L D + G+
Sbjct: 274 RHDSEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKL 333
Query: 57 TGEAFVQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDR 116
GEA V F A+ A+ + E G +P + R ++R
Sbjct: 334 KGEATVSFDDPPSAKAAIDWFDGK--------------EFSG--NPIKVSFATRRADFNR 377
Query: 117 PIGGRGGYYGAGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGF 176
GG G G GRG G YGG GG G GG G SG
Sbjct: 378 --GGGNGRGGRGRGGPMGRGGYGG---------------------GGSGGGGRGGFPSGG 414
Query: 177 HGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAM 236
GG G RA G+ T E+ +
Sbjct: 415 GGG---------------------------------GGQQRA-GDWKCPNPTCENMNFSW 440
Query: 237 SKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGG-YGRDGMDNQGGYGSVGRMGMGNNYSG 295
+ N + G G G GGS MGG YG D +GGY G G G + G
Sbjct: 441 RNECNQCK-------APKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGG 493
Query: 296 GYGTPDGLGGYGRGGGGSGGYYGQG 320
G G GG RGG G G +G
Sbjct: 494 FRG---GRGGGDRGGFGPGKMDSRG 515
Score = 46.6 bits (109), Expect = 3e-05
Identities = 36/84 (42%), Positives = 38/84 (45%), Gaps = 13/84 (15%)
Query: 257 GGGSG--------MGGSGMGGYGRDGMDNQGGYGSVGRMGMG----NNYSGGYGTPDGLG 304
GGGSG GG G GGYG+ +G GS G G G N SGGY P G G
Sbjct: 187 GGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGY-EPRGRG 245
Query: 305 GYGRGGGGSGGYYGQGGMSGGGWR 328
G G GG GG G GG R
Sbjct: 246 GGRGGRGGMGGSDRGGFNKFGGPR 269
Score = 46.2 bits (108), Expect = 4e-05
Identities = 34/77 (44%), Positives = 36/77 (46%), Gaps = 9/77 (11%)
Query: 253 NSTPGGGSGMGGSGM---GGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRG 309
N GG G GG G GG GR G GG G G N SGGY P G GG GRG
Sbjct: 196 NQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGY----NRSSGGY-EPRGRGG-GRG 249
Query: 310 GGGSGGYYGQGGMSGGG 326
G G G +GG + G
Sbjct: 250 GRGGMGGSDRGGFNKFG 266
Score = 42.4 bits (98), Expect = 6e-04
Identities = 24/53 (45%), Positives = 27/53 (50%), Gaps = 6/53 (11%)
Query: 285 GRMGMGNNYSGGYGTPDGLGGYGR------GGGGSGGYYGQGGMSGGGWRGMY 331
G+ N+ SGG G G G YG+ GGGSGG YG SGGG G Y
Sbjct: 156 GQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGY 208
Score = 38.5 bits (88), Expect = 0.008
Identities = 28/75 (37%), Positives = 29/75 (38%), Gaps = 19/75 (25%)
Query: 274 GMDNQGGYGSVGRMGMGNNYSGGYGTPDGL--------GGYGR----GGGGSGGY----- 316
G Q Y S G G G YG GGYG GGGGSGGY
Sbjct: 154 GYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDR 213
Query: 317 --YGQGGMSGGGWRG 329
G+GG GGG G
Sbjct: 214 GGRGRGGSGGGGGGG 228
Score = 37.4 bits (85), Expect = 0.019
Identities = 31/81 (38%), Positives = 34/81 (41%), Gaps = 13/81 (16%)
Query: 115 DRPIGGRGGYYGAG------RGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGG 168
D P GG GG + G RG GG+D GGY G GF R GRG G G G
Sbjct: 453 DGPGGGPGGSHMGGNYGDDRRGGRGGYDR-GGYRGRGGDRGGF----RGGRGGGDRGGFG 507
Query: 169 AGDASSGFHGGHFVHMRGLPF 189
G S G H R P+
Sbjct: 508 PGKMDS--RGEHRQDRRERPY 526
Score = 36.2 bits (82), Expect = 0.042
Identities = 31/125 (24%), Positives = 38/125 (30%), Gaps = 51/125 (40%)
Query: 254 STPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGR----- 308
STP G GG G + Q Y G+ ++ SG YG+ YG+
Sbjct: 70 STPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGS 129
Query: 309 ---------------------------------------GGGGSGGYYGQ-------GGM 322
GGGG GG YGQ GG
Sbjct: 130 YSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGG 189
Query: 323 SGGGW 327
SGGG+
Sbjct: 190 SGGGY 194
Score = 30.4 bits (67), Expect = 2.3
Identities = 20/62 (32%), Positives = 24/62 (38%), Gaps = 7/62 (11%)
Query: 263 GGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGG-----GSGGYY 317
G GY + + GYG G + + GYGT GYG GG S Y
Sbjct: 34 GQQSYSGYSQS--TDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSY 91
Query: 318 GQ 319
GQ
Sbjct: 92 GQ 93
Score = 29.3 bits (64), Expect = 5.1
Identities = 28/100 (28%), Positives = 32/100 (32%), Gaps = 21/100 (21%)
Query: 253 NSTPGGGSGMGGSGMGG-YGRDGMDNQGGYGSVGRMGMGNNYSG---------GYGTPDG 302
+S PG G S G YG + G G +Y G Y P G
Sbjct: 95 SSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQG 154
Query: 303 LGGYGRGGGGSGGYYGQGG-----------MSGGGWRGMY 331
G + SGG G GG SGGG G Y
Sbjct: 155 YGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGY 194
>gi|45935393 RNA binding motif protein 35B [Homo sapiens]
Length = 717
Score = 73.6 bits (179), Expect = 2e-13
Identities = 32/82 (39%), Positives = 53/82 (64%)
Query: 14 SDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENA 73
S+ VR RGLP+ S +++ +FF+GL + G+ L ++ QGR GEA ++F E + A
Sbjct: 245 SETVVRARGLPWQSSDQDVARFFKGLNVARGGVALCLNAQGRRNGEALIRFVDSEQRDLA 304
Query: 74 LGKHKERIGHRYIEIFRSSRSE 95
L +HK +G RYIE+++++ E
Sbjct: 305 LQRHKHHMGVRYIEVYKATGEE 326
Score = 62.4 bits (150), Expect = 5e-10
Identities = 35/84 (41%), Positives = 52/84 (61%), Gaps = 5/84 (5%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDY----QGRSTGEAFVQFASKEIAENA 73
+RLRGLPF +++ F G E G T + + GR TG+AF FA +E+A+ A
Sbjct: 350 LRLRGLPFSAGPTDVLGFL-GPECPVTGGTEGLLFVRHPDGRPTGDAFALFACEELAQAA 408
Query: 74 LGKHKERIGHRYIEIFRSSRSEIK 97
L +HK +G RYIE+FRS+ +E++
Sbjct: 409 LRRHKGMLGKRYIELFRSTAAEVQ 432
Score = 56.2 bits (134), Expect = 4e-08
Identities = 31/82 (37%), Positives = 50/82 (60%), Gaps = 3/82 (3%)
Query: 18 VRLRGLPFGCSKEEIVQFF--QGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALG 75
VRLRGLP+ + E+I+ F +I P+G+ + ++ QGR +G+AF+Q S E A A
Sbjct: 467 VRLRGLPYTATIEDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQMTSAERALAAAQ 526
Query: 76 K-HKERIGHRYIEIFRSSRSEI 96
+ HK+ + RY+E+ S E+
Sbjct: 527 RCHKKVMKERYVEVVPCSTEEM 548
Score = 55.1 bits (131), Expect = 9e-08
Identities = 29/72 (40%), Positives = 44/72 (61%), Gaps = 2/72 (2%)
Query: 182 VHMRGLPFRATENDIANFFSPLNPIR--VHIDIGADGRATGEADVEFVTHEDAVAAMSKD 239
V RGLP+++++ D+A FF LN R V + + A GR GEA + FV E A+ +
Sbjct: 249 VRARGLPWQSSDQDVARFFKGLNVARGGVALCLNAQGRRNGEALIRFVDSEQRDLALQRH 308
Query: 240 KNNMQHRYIELF 251
K++M RYIE++
Sbjct: 309 KHHMGVRYIEVY 320
Score = 50.1 bits (118), Expect = 3e-06
Identities = 35/103 (33%), Positives = 53/103 (51%), Gaps = 8/103 (7%)
Query: 178 GGHFVHMRGLPFRATENDIANFF----SPLNPIRVHIDIGADGRATGEADVEFVTHEDAV 233
G V +RGLP+ AT DI +F + + P VH+ + GR +G+A ++ + E A+
Sbjct: 463 GRDCVRLRGLPYTATIEDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQMTSAERAL 522
Query: 234 AAMSK-DKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGM 275
AA + K M+ RY+E+ ST + G G GR GM
Sbjct: 523 AAAQRCHKKVMKERYVEVVPCSTEEMSRVLMG---GTLGRSGM 562
Score = 45.8 bits (107), Expect = 5e-05
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 5/75 (6%)
Query: 182 VHMRGLPFRATENDIANFFSPLNPIRVHID-----IGADGRATGEADVEFVTHEDAVAAM 236
+ +RGLPF A D+ F P P+ + DGR TG+A F E A AA+
Sbjct: 350 LRLRGLPFSAGPTDVLGFLGPECPVTGGTEGLLFVRHPDGRPTGDAFALFACEELAQAAL 409
Query: 237 SKDKNNMQHRYIELF 251
+ K + RYIELF
Sbjct: 410 RRHKGMLGKRYIELF 424
>gi|19923345 RNA binding motif protein 12 [Homo sapiens]
Length = 932
Score = 72.0 bits (175), Expect = 7e-13
Identities = 76/321 (23%), Positives = 126/321 (39%), Gaps = 67/321 (20%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
V L+GLPF + ++ FF+ L+IV + I + G++TGE FV+F ++ + AL +H
Sbjct: 432 VYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAALCRH 491
Query: 78 KERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSYGGFDD 137
K+ +G+R+I++ ++ + D R+ L
Sbjct: 492 KQYMGNRFIQVHPITKKGMLEKIDMIRKRL------------------------------ 521
Query: 138 YGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIA 197
N+ Y D R M + G A H+ +PF T+ D+
Sbjct: 522 ----QNFSY----------DQREMILNPEGDVNSAKV------CAHITNIPFSITKMDVL 561
Query: 198 NFFS--PLNPIRVHIDIGADGRATGEADVEFVTHEDAVAA--MSKDKNNMQHRYI----- 248
F P++ VH+ + +G+ G+A V+F +DA + + + K N + ++
Sbjct: 562 QFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHRKKLNGREAFVHVVTL 621
Query: 249 ----ELFLNSTPGGGSGMGGSGMGGYGRDGMDNQG----GYGSVGRMGMGNNYSGGYGTP 300
E+ N G G+ G GM N G G S G G G +G G+
Sbjct: 622 EDMREIEKNPPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSA 681
Query: 301 DGLGGYGRGGGGSGGYYGQGG 321
G G S G GG
Sbjct: 682 ITSAGLPGAGMPSAGIPSAGG 702
Score = 58.5 bits (140), Expect = 8e-09
Identities = 76/337 (22%), Positives = 126/337 (37%), Gaps = 36/337 (10%)
Query: 2 DWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAF 61
+ ++ G +++ + +PF +K +++QF +G+ + N + + +D G+ G+A
Sbjct: 530 EMILNPEGDVNSAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQAL 589
Query: 62 VQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGF-YDPPRRLLGQRPGPYDRPIGG 120
VQF +++ A + H++++ R + + +++ +PP Q P+ G
Sbjct: 590 VQFKNEDDARKSERLHRKKLNGREAFVHVVTLEDMREIEKNPP----AQGKKGLKMPVPG 645
Query: 121 RGGYYGAGRGSYGGFD-DYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGG 179
G G G G + G G+ G G AG S+G
Sbjct: 646 NPAVPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEH 705
Query: 180 HFVHM------RGLPFRATEN-DIANFFSPLNPIRVHIDIGADGRATGEADVEFVT-HED 231
F+ + G PF N +N F P P G G A G+A +
Sbjct: 706 AFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIP-----PPGLGGGAFGDARPGMPSVGNS 760
Query: 232 AVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGG-SGMGGYGRDGMDNQGGYGSV-GRMGM 289
+ + D PG G G SG G+G + G GS+ G G
Sbjct: 761 GLPGLGLD---------------VPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGF 805
Query: 290 GNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGGG 326
G+ G P LGG G G G G G + GG
Sbjct: 806 GSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGG 842
Score = 53.5 bits (127), Expect = 3e-07
Identities = 28/79 (35%), Positives = 45/79 (56%), Gaps = 2/79 (2%)
Query: 174 SGFHGGHFVHMRGLPFRATENDIANFFSPLNPIR--VHIDIGADGRATGEADVEFVTHED 231
S G V+++GLPF A + +FF L+ + ++I G +G+ATGE VEF D
Sbjct: 424 SPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEAD 483
Query: 232 AVAAMSKDKNNMQHRYIEL 250
AA+ + K M +R+I++
Sbjct: 484 YKAALCRHKQYMGNRFIQV 502
Score = 48.9 bits (115), Expect = 6e-06
Identities = 24/70 (34%), Positives = 40/70 (57%)
Query: 181 FVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDK 240
+V + G+PF A END+ +FF L VH+ GR G V+F++ +D A+ +++
Sbjct: 305 YVSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEALKRNR 364
Query: 241 NNMQHRYIEL 250
M RY+E+
Sbjct: 365 MLMIQRYVEV 374
Score = 48.9 bits (115), Expect = 6e-06
Identities = 24/72 (33%), Positives = 44/72 (61%), Gaps = 1/72 (1%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
++++ +PF S +EI+ FF G +++P + L + +G TGEA V F S++ A A+
Sbjct: 858 IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVIDL 917
Query: 78 KER-IGHRYIEI 88
+R IG R +++
Sbjct: 918 NDRPIGSRKVKL 929
Score = 45.8 bits (107), Expect = 5e-05
Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 2/79 (2%)
Query: 10 PNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEI 69
P + D V + G+PF + ++ FF GL + + + L D+ GR+ G V+F S +
Sbjct: 298 PINPDDLYVSVHGMPFSAMENDVRDFFHGLRV--DAVHLLKDHVGRNNGNGLVKFLSPQD 355
Query: 70 AENALGKHKERIGHRYIEI 88
AL +++ + RY+E+
Sbjct: 356 TFEALKRNRMLMIQRYVEV 374
Score = 42.7 bits (99), Expect = 4e-04
Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
+RL+GLP +I FF GL I G+ + G GEAF+ FA+ E A + +
Sbjct: 5 IRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIV----GGELGEAFIVFATDEDARLGMMRT 60
Query: 78 KERIGHRYIEIFRSSRSEIKGFYDPPRR 105
I + + SS++E++ + RR
Sbjct: 61 GGTIKGSKVTLLLSSKTEMQNMIELSRR 88
Score = 41.2 bits (95), Expect = 0.001
Identities = 46/155 (29%), Positives = 65/155 (41%), Gaps = 21/155 (13%)
Query: 95 EIKGFYDPPRRLLGQRPGPYDRPIGGRGG--YYGAGRGSYGGFDDYG-GYNNYGY----- 146
++ GF P L G P G GG +G G GS GG +G G G
Sbjct: 768 DVPGFGGGPNNLSG--------PSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHL 819
Query: 147 -GNDGFDDRMRDGRGMGGHGYGGAGD--ASSGFHGGHFVHMRGLPFRATENDIANFF--S 201
G F G G G GG +SSG G + ++ +PF + ++I +FF
Sbjct: 820 GGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGPTVIKVQNMPFTVSIDEILDFFYGY 879
Query: 202 PLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAM 236
+ P V + G TGEA V F + ++A AA+
Sbjct: 880 QVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAV 914
Score = 33.9 bits (76), Expect = 0.21
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 6/75 (8%)
Query: 182 VHMRGLPFRATENDIANFFSPLN--PIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKD 239
+ ++GLP A DI +FFS L VHI G GEA + F T EDA M +
Sbjct: 5 IRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIV----GGELGEAFIVFATDEDARLGMMRT 60
Query: 240 KNNMQHRYIELFLNS 254
++ + L L+S
Sbjct: 61 GGTIKGSKVTLLLSS 75
>gi|23510462 RNA binding motif protein 12 [Homo sapiens]
Length = 932
Score = 72.0 bits (175), Expect = 7e-13
Identities = 76/321 (23%), Positives = 126/321 (39%), Gaps = 67/321 (20%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
V L+GLPF + ++ FF+ L+IV + I + G++TGE FV+F ++ + AL +H
Sbjct: 432 VYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAALCRH 491
Query: 78 KERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSYGGFDD 137
K+ +G+R+I++ ++ + D R+ L
Sbjct: 492 KQYMGNRFIQVHPITKKGMLEKIDMIRKRL------------------------------ 521
Query: 138 YGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGGHFVHMRGLPFRATENDIA 197
N+ Y D R M + G A H+ +PF T+ D+
Sbjct: 522 ----QNFSY----------DQREMILNPEGDVNSAKV------CAHITNIPFSITKMDVL 561
Query: 198 NFFS--PLNPIRVHIDIGADGRATGEADVEFVTHEDAVAA--MSKDKNNMQHRYI----- 248
F P++ VH+ + +G+ G+A V+F +DA + + + K N + ++
Sbjct: 562 QFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHRKKLNGREAFVHVVTL 621
Query: 249 ----ELFLNSTPGGGSGMGGSGMGGYGRDGMDNQG----GYGSVGRMGMGNNYSGGYGTP 300
E+ N G G+ G GM N G G S G G G +G G+
Sbjct: 622 EDMREIEKNPPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSA 681
Query: 301 DGLGGYGRGGGGSGGYYGQGG 321
G G S G GG
Sbjct: 682 ITSAGLPGAGMPSAGIPSAGG 702
Score = 58.5 bits (140), Expect = 8e-09
Identities = 76/337 (22%), Positives = 126/337 (37%), Gaps = 36/337 (10%)
Query: 2 DWVMKHNGPNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAF 61
+ ++ G +++ + +PF +K +++QF +G+ + N + + +D G+ G+A
Sbjct: 530 EMILNPEGDVNSAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQAL 589
Query: 62 VQFASKEIAENALGKHKERIGHRYIEIFRSSRSEIKGF-YDPPRRLLGQRPGPYDRPIGG 120
VQF +++ A + H++++ R + + +++ +PP Q P+ G
Sbjct: 590 VQFKNEDDARKSERLHRKKLNGREAFVHVVTLEDMREIEKNPP----AQGKKGLKMPVPG 645
Query: 121 RGGYYGAGRGSYGGFD-DYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHGG 179
G G G G + G G+ G G AG S+G
Sbjct: 646 NPAVPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEH 705
Query: 180 HFVHM------RGLPFRATEN-DIANFFSPLNPIRVHIDIGADGRATGEADVEFVT-HED 231
F+ + G PF N +N F P P G G A G+A +
Sbjct: 706 AFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIP-----PPGLGGGAFGDARPGMPSVGNS 760
Query: 232 AVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGG-SGMGGYGRDGMDNQGGYGSV-GRMGM 289
+ + D PG G G SG G+G + G GS+ G G
Sbjct: 761 GLPGLGLD---------------VPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGF 805
Query: 290 GNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMSGGG 326
G+ G P LGG G G G G G + GG
Sbjct: 806 GSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGG 842
Score = 53.5 bits (127), Expect = 3e-07
Identities = 28/79 (35%), Positives = 45/79 (56%), Gaps = 2/79 (2%)
Query: 174 SGFHGGHFVHMRGLPFRATENDIANFFSPLNPIR--VHIDIGADGRATGEADVEFVTHED 231
S G V+++GLPF A + +FF L+ + ++I G +G+ATGE VEF D
Sbjct: 424 SPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEAD 483
Query: 232 AVAAMSKDKNNMQHRYIEL 250
AA+ + K M +R+I++
Sbjct: 484 YKAALCRHKQYMGNRFIQV 502
Score = 48.9 bits (115), Expect = 6e-06
Identities = 24/70 (34%), Positives = 40/70 (57%)
Query: 181 FVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDK 240
+V + G+PF A END+ +FF L VH+ GR G V+F++ +D A+ +++
Sbjct: 305 YVSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEALKRNR 364
Query: 241 NNMQHRYIEL 250
M RY+E+
Sbjct: 365 MLMIQRYVEV 374
Score = 48.9 bits (115), Expect = 6e-06
Identities = 24/72 (33%), Positives = 44/72 (61%), Gaps = 1/72 (1%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
++++ +PF S +EI+ FF G +++P + L + +G TGEA V F S++ A A+
Sbjct: 858 IKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVIDL 917
Query: 78 KER-IGHRYIEI 88
+R IG R +++
Sbjct: 918 NDRPIGSRKVKL 929
Score = 45.8 bits (107), Expect = 5e-05
Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 2/79 (2%)
Query: 10 PNDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEI 69
P + D V + G+PF + ++ FF GL + + + L D+ GR+ G V+F S +
Sbjct: 298 PINPDDLYVSVHGMPFSAMENDVRDFFHGLRV--DAVHLLKDHVGRNNGNGLVKFLSPQD 355
Query: 70 AENALGKHKERIGHRYIEI 88
AL +++ + RY+E+
Sbjct: 356 TFEALKRNRMLMIQRYVEV 374
Score = 42.7 bits (99), Expect = 4e-04
Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
Query: 18 VRLRGLPFGCSKEEIVQFFQGLEIVPNGITLTMDYQGRSTGEAFVQFASKEIAENALGKH 77
+RL+GLP +I FF GL I G+ + G GEAF+ FA+ E A + +
Sbjct: 5 IRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIV----GGELGEAFIVFATDEDARLGMMRT 60
Query: 78 KERIGHRYIEIFRSSRSEIKGFYDPPRR 105
I + + SS++E++ + RR
Sbjct: 61 GGTIKGSKVTLLLSSKTEMQNMIELSRR 88
Score = 41.2 bits (95), Expect = 0.001
Identities = 46/155 (29%), Positives = 65/155 (41%), Gaps = 21/155 (13%)
Query: 95 EIKGFYDPPRRLLGQRPGPYDRPIGGRGG--YYGAGRGSYGGFDDYG-GYNNYGY----- 146
++ GF P L G P G GG +G G GS GG +G G G
Sbjct: 768 DVPGFGGGPNNLSG--------PSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHL 819
Query: 147 -GNDGFDDRMRDGRGMGGHGYGGAGD--ASSGFHGGHFVHMRGLPFRATENDIANFF--S 201
G F G G G GG +SSG G + ++ +PF + ++I +FF
Sbjct: 820 GGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGPTVIKVQNMPFTVSIDEILDFFYGY 879
Query: 202 PLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAM 236
+ P V + G TGEA V F + ++A AA+
Sbjct: 880 QVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAV 914
Score = 33.9 bits (76), Expect = 0.21
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 6/75 (8%)
Query: 182 VHMRGLPFRATENDIANFFSPLN--PIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKD 239
+ ++GLP A DI +FFS L VHI G GEA + F T EDA M +
Sbjct: 5 IRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIV----GGELGEAFIVFATDEDARLGMMRT 60
Query: 240 KNNMQHRYIELFLNS 254
++ + L L+S
Sbjct: 61 GGTIKGSKVTLLLSS 75
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 70.1 bits (170), Expect = 3e-12
Identities = 73/259 (28%), Positives = 98/259 (37%), Gaps = 59/259 (22%)
Query: 108 GQRPGPYDRPIGGRGGYYGAGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYG 167
G+ G YD+ GRG G+ G GGF ++GG+ +YG D
Sbjct: 181 GRGRGGYDKD--GRGPMTGSSGGDRGGFKNFGGHRDYGPRTD------------------ 220
Query: 168 GAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGA----------DGR 217
D+ S + + ++GL + + + FF + I+ + G G+
Sbjct: 221 --ADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGK 278
Query: 218 ATGEADVEFVTHEDAVAAMS-KDKNNMQHRYIEL-FLNSTP----GGGSGMGGSGMGGY- 270
GEA V F A AA+ D I++ F P GGGSG G G GGY
Sbjct: 279 PKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYR 338
Query: 271 GRDGMDNQGG----------YGSVGRMGMGNNYSGGY--------GTPDGLGGYGRGGGG 312
GR G +GG S G M S P G GRG GG
Sbjct: 339 GRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGG 398
Query: 313 SGGYYGQGGMSG--GGWRG 329
GY G+GG G GG+ G
Sbjct: 399 ERGYRGRGGRGGDRGGYGG 417
Score = 63.9 bits (154), Expect = 2e-10
Identities = 109/391 (27%), Positives = 137/391 (35%), Gaps = 116/391 (29%)
Query: 11 NDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNG-------ITLTMDYQ-GRSTGEAFV 62
+++ + T+ ++GL G S +++ +FF+ + I+ I L D G+ GEA V
Sbjct: 226 DNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATV 285
Query: 63 QFASKEIAENALG--KHKERIGHRYIEIFRSSRSEI------------KGFY-------- 100
F A+ A+ KE G+ F + R E +G Y
Sbjct: 286 SFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQG 345
Query: 101 ---DP-------PRRLLGQ-------------RPGPYD-RPIGG--RGGYYGA-----GR 129
DP P G P P D RP GG RG YG GR
Sbjct: 346 RGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGR 405
Query: 130 GSYGGFDDYGGY----NNYGYGNDGFDDRMRDGRGMGGHGYGG--AGDASSGFHGGHFVH 183
G GG D GGY + GYG D G GG GYGG +G G GG +
Sbjct: 406 GGRGG--DRGGYGGDRSGGGYGGDRSSGGGYSGDRSGG-GYGGDRSGGGYGGDRGGGYGG 462
Query: 184 MRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNM 243
RG + G D G D D+
Sbjct: 463 DRGGGYGGDRGG---------------GYGGDRGGYGG---------DRGGGYGGDRGGY 498
Query: 244 QHRYIELFLNSTPGGGSGMGGSGMGGYGRD-----GMDNQGGYGSV--GRMGMGNNYSGG 296
GG G G GGYG D G ++GGYG G G G + SGG
Sbjct: 499 -------------GGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGG 545
Query: 297 YGTPDGLGGYG--RGGGGSGGYYGQGGMSGG 325
YG GGYG RGGG G G GG GG
Sbjct: 546 YGGDRSGGGYGGDRGGGYGGDRGGYGGKMGG 576
Score = 52.8 bits (125), Expect = 4e-07
Identities = 34/74 (45%), Positives = 37/74 (50%), Gaps = 4/74 (5%)
Query: 259 GSGMGGSGMGGYGRDGMDNQGGYGSV-GRMGMGNNYSGGYGTPDGLGGYG--RGGGGSGG 315
G G GG G G G + GGYG G G + GGYG G GGYG RGGG G
Sbjct: 421 GGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRG-GGYGGDRGGGYGGD 479
Query: 316 YYGQGGMSGGGWRG 329
G GG GGG+ G
Sbjct: 480 RGGYGGDRGGGYGG 493
Score = 52.4 bits (124), Expect = 6e-07
Identities = 62/211 (29%), Positives = 69/211 (32%), Gaps = 34/211 (16%)
Query: 116 RPIGGRGGYYGAG-----RGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGH----GY 166
R GG GY G G RG YGG GGY G+ R G G GG GY
Sbjct: 394 RGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGD-RSGGGYGGDRSGGGY 452
Query: 167 GG-AGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVE 225
GG G G GG + RG + G G G +
Sbjct: 453 GGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRG-----------GGYGGDRGGYGGD 501
Query: 226 FVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVG 285
+ D+ GGGSG GG GGYG D GG
Sbjct: 502 RGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGD---RSGG----- 553
Query: 286 RMGMGNNYSGGYGTPDGLGGYGRGGGGSGGY 316
G G + GGYG GGYG GG Y
Sbjct: 554 --GYGGDRGGGYG--GDRGGYGGKMGGRNDY 580
Score = 48.9 bits (115), Expect = 6e-06
Identities = 38/84 (45%), Positives = 39/84 (46%), Gaps = 15/84 (17%)
Query: 259 GSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSG-----GYGTPDGLGGYG--RGGG 311
G G G GGYG D + GGYG G G YSG GYG GGYG RGGG
Sbjct: 404 GRGGRGGDRGGYGGDR--SGGGYG--GDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGG 459
Query: 312 ----GSGGYYGQGGMSGGGWRGMY 331
GGY G G GG RG Y
Sbjct: 460 YGGDRGGGYGGDRGGGYGGDRGGY 483
Score = 45.4 bits (106), Expect = 7e-05
Identities = 39/90 (43%), Positives = 44/90 (48%), Gaps = 15/90 (16%)
Query: 253 NSTPGGGS--GMGGSGMGGY-GRDGMD-NQGGYG---SVGRMGMGNNYSGGYGTPDGLGG 305
+S P GG G G G GY GR G ++GGYG S G G + GGY GG
Sbjct: 383 DSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGG 442
Query: 306 YG--RGGGG----SGGYYGQGGMSGGGWRG 329
YG R GGG GG G GG GGG+ G
Sbjct: 443 YGGDRSGGGYGGDRGG--GYGGDRGGGYGG 470
Score = 32.7 bits (73), Expect = 0.46
Identities = 52/224 (23%), Positives = 73/224 (32%), Gaps = 42/224 (18%)
Query: 123 GYYGAGRGSYGGFDDYGGYNNYGYGN-----DGFDDRMRDGRGMGGHGYGGAGDASSGFH 177
G YG G + YG + GYG G+ G GY G + S +
Sbjct: 5 GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSY 64
Query: 178 GGHFVHMRGLPFRATENDIANFFS--PLNPIRVHIDIGADGRATGEA------------- 222
GG+ EN + +S P N ++ + G G A
Sbjct: 65 GGY------------ENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDS 112
Query: 223 ---DVEFVTHEDAVAAMSK-DKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQ 278
+ H+ + S D+ + + + +S S R G DN+
Sbjct: 113 YDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNR 172
Query: 279 GGYGSVGRMGMGNNYSGGYGTPDGLGGY-GRGGGGSGGYYGQGG 321
G GS G G GGY DG G G GG GG+ GG
Sbjct: 173 GYGGSQG----GGRGRGGY-DKDGRGPMTGSSGGDRGGFKNFGG 211
Score = 28.9 bits (63), Expect = 6.6
Identities = 20/41 (48%), Positives = 21/41 (51%), Gaps = 10/41 (24%)
Query: 108 GQRPGPY--DRPIGG----RGGYYGAGRGSYG----GFDDY 138
G R G Y DR GG RGG YG RG YG G +DY
Sbjct: 540 GDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDY 580
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 70.1 bits (170), Expect = 3e-12
Identities = 73/259 (28%), Positives = 98/259 (37%), Gaps = 59/259 (22%)
Query: 108 GQRPGPYDRPIGGRGGYYGAGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYG 167
G+ G YD+ GRG G+ G GGF ++GG+ +YG D
Sbjct: 184 GRGRGGYDKD--GRGPMTGSSGGDRGGFKNFGGHRDYGPRTD------------------ 223
Query: 168 GAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGA----------DGR 217
D+ S + + ++GL + + + FF + I+ + G G+
Sbjct: 224 --ADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGK 281
Query: 218 ATGEADVEFVTHEDAVAAMS-KDKNNMQHRYIEL-FLNSTP----GGGSGMGGSGMGGY- 270
GEA V F A AA+ D I++ F P GGGSG G G GGY
Sbjct: 282 PKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYR 341
Query: 271 GRDGMDNQGG----------YGSVGRMGMGNNYSGGY--------GTPDGLGGYGRGGGG 312
GR G +GG S G M S P G GRG GG
Sbjct: 342 GRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGG 401
Query: 313 SGGYYGQGGMSG--GGWRG 329
GY G+GG G GG+ G
Sbjct: 402 ERGYRGRGGRGGDRGGYGG 420
Score = 63.9 bits (154), Expect = 2e-10
Identities = 109/391 (27%), Positives = 137/391 (35%), Gaps = 116/391 (29%)
Query: 11 NDASDGTVRLRGLPFGCSKEEIVQFFQGLEIVPNG-------ITLTMDYQ-GRSTGEAFV 62
+++ + T+ ++GL G S +++ +FF+ + I+ I L D G+ GEA V
Sbjct: 229 DNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEATV 288
Query: 63 QFASKEIAENALG--KHKERIGHRYIEIFRSSRSEI------------KGFY-------- 100
F A+ A+ KE G+ F + R E +G Y
Sbjct: 289 SFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQG 348
Query: 101 ---DP-------PRRLLGQ-------------RPGPYD-RPIGG--RGGYYGA-----GR 129
DP P G P P D RP GG RG YG GR
Sbjct: 349 RGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGR 408
Query: 130 GSYGGFDDYGGY----NNYGYGNDGFDDRMRDGRGMGGHGYGG--AGDASSGFHGGHFVH 183
G GG D GGY + GYG D G GG GYGG +G G GG +
Sbjct: 409 GGRGG--DRGGYGGDRSGGGYGGDRSSGGGYSGDRSGG-GYGGDRSGGGYGGDRGGGYGG 465
Query: 184 MRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSKDKNNM 243
RG + G D G D D+
Sbjct: 466 DRGGGYGGDRGG---------------GYGGDRGGYGG---------DRGGGYGGDRGGY 501
Query: 244 QHRYIELFLNSTPGGGSGMGGSGMGGYGRD-----GMDNQGGYGSV--GRMGMGNNYSGG 296
GG G G GGYG D G ++GGYG G G G + SGG
Sbjct: 502 -------------GGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGG 548
Query: 297 YGTPDGLGGYG--RGGGGSGGYYGQGGMSGG 325
YG GGYG RGGG G G GG GG
Sbjct: 549 YGGDRSGGGYGGDRGGGYGGDRGGYGGKMGG 579
Score = 52.8 bits (125), Expect = 4e-07
Identities = 34/74 (45%), Positives = 37/74 (50%), Gaps = 4/74 (5%)
Query: 259 GSGMGGSGMGGYGRDGMDNQGGYGSV-GRMGMGNNYSGGYGTPDGLGGYG--RGGGGSGG 315
G G GG G G G + GGYG G G + GGYG G GGYG RGGG G
Sbjct: 424 GGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRG-GGYGGDRGGGYGGD 482
Query: 316 YYGQGGMSGGGWRG 329
G GG GGG+ G
Sbjct: 483 RGGYGGDRGGGYGG 496
Score = 52.4 bits (124), Expect = 6e-07
Identities = 62/211 (29%), Positives = 69/211 (32%), Gaps = 34/211 (16%)
Query: 116 RPIGGRGGYYGAG-----RGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGH----GY 166
R GG GY G G RG YGG GGY G+ R G G GG GY
Sbjct: 397 RGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGD-RSGGGYGGDRSGGGY 455
Query: 167 GG-AGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVE 225
GG G G GG + RG + G G G +
Sbjct: 456 GGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRG-----------GGYGGDRGGYGGD 504
Query: 226 FVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVG 285
+ D+ GGGSG GG GGYG D GG
Sbjct: 505 RGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGD---RSGG----- 556
Query: 286 RMGMGNNYSGGYGTPDGLGGYGRGGGGSGGY 316
G G + GGYG GGYG GG Y
Sbjct: 557 --GYGGDRGGGYG--GDRGGYGGKMGGRNDY 583
Score = 48.9 bits (115), Expect = 6e-06
Identities = 38/84 (45%), Positives = 39/84 (46%), Gaps = 15/84 (17%)
Query: 259 GSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSG-----GYGTPDGLGGYG--RGGG 311
G G G GGYG D + GGYG G G YSG GYG GGYG RGGG
Sbjct: 407 GRGGRGGDRGGYGGDR--SGGGYG--GDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGG 462
Query: 312 ----GSGGYYGQGGMSGGGWRGMY 331
GGY G G GG RG Y
Sbjct: 463 YGGDRGGGYGGDRGGGYGGDRGGY 486
Score = 33.1 bits (74), Expect = 0.35
Identities = 53/227 (23%), Positives = 75/227 (33%), Gaps = 45/227 (19%)
Query: 123 GYYGAGRGSYGGFDDYGGYNNYGYGN-----DGFDDRMRDGRGMGGHGYGGAGDASSGF- 176
G YG G + YG + GYG G+ G GY G + SG+
Sbjct: 5 GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYS 64
Query: 177 --HGGHFVHMRGLPFRATENDIANFFS--PLNPIRVHIDIGADGRATGEA---------- 222
+GG+ EN + +S P N ++ + G G A
Sbjct: 65 QSYGGY------------ENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQ 112
Query: 223 ------DVEFVTHEDAVAAMSK-DKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGM 275
+ H+ + S D+ + + + +S S R G
Sbjct: 113 QDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGE 172
Query: 276 DNQGGYGSVGRMGMGNNYSGGYGTPDGLGGY-GRGGGGSGGYYGQGG 321
DN+G GS G G GGY DG G G GG GG+ GG
Sbjct: 173 DNRGYGGSQG----GGRGRGGY-DKDGRGPMTGSSGGDRGGFKNFGG 214
Score = 28.9 bits (63), Expect = 6.6
Identities = 20/41 (48%), Positives = 21/41 (51%), Gaps = 10/41 (24%)
Query: 108 GQRPGPY--DRPIGG----RGGYYGAGRGSYG----GFDDY 138
G R G Y DR GG RGG YG RG YG G +DY
Sbjct: 543 GDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDY 583
>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
sapiens]
Length = 898
Score = 65.1 bits (157), Expect = 8e-11
Identities = 72/246 (29%), Positives = 97/246 (39%), Gaps = 50/246 (20%)
Query: 102 PPRRLLGQRPGPYDRPIGGRGGYYGAGRGSYGGFDDYG-GYNNYGYGNDGFDDRMRDGRG 160
PP L G+ G I GRG G G ++GG+ + G GY +YGYG +
Sbjct: 639 PPPNLRGRGRGG---SIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYS 695
Query: 161 MGGH------GYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGA 214
GGH G GG G SSG+ G ++ + D N+ SP+ P
Sbjct: 696 NGGHSGNASGGGGGGGGGSSGY-GSYY-----------QGD--NYNSPVPPKHAGKKQPH 741
Query: 215 DGRATGEADVEFVTHEDAVAAMS--------------KDKNNMQHRYIELFLNSTPGGGS 260
G+ + +H+ + + K N+ Q Y ++PGGG
Sbjct: 742 GGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGG 801
Query: 261 GMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGT--PDGLGGYGRGGGGSGGYYG 318
G Y + N G G GR G GN+Y G + P GGYG G GG Y G
Sbjct: 802 G------SDYNYESKFNYSGSG--GRSG-GNSYGSGGASYNPGSHGGYGGGSGGGSSYQG 852
Query: 319 -QGGMS 323
QGG S
Sbjct: 853 KQGGYS 858
Score = 42.0 bits (97), Expect = 8e-04
Identities = 31/73 (42%), Positives = 34/73 (46%), Gaps = 3/73 (4%)
Query: 259 GSGMGGSGMG-GYGRD-GMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGY 316
G G GGS G G GR G N GGY + G G G+ GG G + GG SG
Sbjct: 645 GRGRGGSIRGRGRGRGFGGANHGGYMNAG-AGYGSYGYGGNSATAGYSQFYSNGGHSGNA 703
Query: 317 YGQGGMSGGGWRG 329
G GG GGG G
Sbjct: 704 SGGGGGGGGGSSG 716
Score = 28.9 bits (63), Expect = 6.6
Identities = 21/74 (28%), Positives = 28/74 (37%), Gaps = 11/74 (14%)
Query: 264 GSGMGGYGRD------GMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYY 317
G GMGG + + +G GS+ G G + G GGY G G G Y
Sbjct: 626 GFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA-----NHGGYMNAGAGYGSYG 680
Query: 318 GQGGMSGGGWRGMY 331
G + G+ Y
Sbjct: 681 YGGNSATAGYSQFY 694
>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
sapiens]
Length = 894
Score = 65.1 bits (157), Expect = 8e-11
Identities = 72/246 (29%), Positives = 97/246 (39%), Gaps = 50/246 (20%)
Query: 102 PPRRLLGQRPGPYDRPIGGRGGYYGAGRGSYGGFDDYG-GYNNYGYGNDGFDDRMRDGRG 160
PP L G+ G I GRG G G ++GG+ + G GY +YGYG +
Sbjct: 635 PPPNLRGRGRGG---SIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYS 691
Query: 161 MGGH------GYGGAGDASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGA 214
GGH G GG G SSG+ G ++ + D N+ SP+ P
Sbjct: 692 NGGHSGNASGGGGGGGGGSSGY-GSYY-----------QGD--NYNSPVPPKHAGKKQPH 737
Query: 215 DGRATGEADVEFVTHEDAVAAMS--------------KDKNNMQHRYIELFLNSTPGGGS 260
G+ + +H+ + + K N+ Q Y ++PGGG
Sbjct: 738 GGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGG 797
Query: 261 GMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGT--PDGLGGYGRGGGGSGGYYG 318
G Y + N G G GR G GN+Y G + P GGYG G GG Y G
Sbjct: 798 G------SDYNYESKFNYSGSG--GRSG-GNSYGSGGASYNPGSHGGYGGGSGGGSSYQG 848
Query: 319 -QGGMS 323
QGG S
Sbjct: 849 KQGGYS 854
Score = 42.0 bits (97), Expect = 8e-04
Identities = 31/73 (42%), Positives = 34/73 (46%), Gaps = 3/73 (4%)
Query: 259 GSGMGGSGMG-GYGRD-GMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGY 316
G G GGS G G GR G N GGY + G G G+ GG G + GG SG
Sbjct: 641 GRGRGGSIRGRGRGRGFGGANHGGYMNAG-AGYGSYGYGGNSATAGYSQFYSNGGHSGNA 699
Query: 317 YGQGGMSGGGWRG 329
G GG GGG G
Sbjct: 700 SGGGGGGGGGSSG 712
Score = 28.9 bits (63), Expect = 6.6
Identities = 21/74 (28%), Positives = 28/74 (37%), Gaps = 11/74 (14%)
Query: 264 GSGMGGYGRD------GMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYY 317
G GMGG + + +G GS+ G G + G GGY G G G Y
Sbjct: 622 GFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGA-----NHGGYMNAGAGYGSYG 676
Query: 318 GQGGMSGGGWRGMY 331
G + G+ Y
Sbjct: 677 YGGNSATAGYSQFY 690
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 63.2 bits (152), Expect = 3e-10
Identities = 39/80 (48%), Positives = 42/80 (52%), Gaps = 5/80 (6%)
Query: 257 GGGSGMGGSGMGGYGR-DGMDNQGGYGSVGRMGMGNNYSGGYGTPDGL-GGYGRGG---G 311
GGGSG GG GGYG G + GG G G G NY GG G+ G GGYG G G
Sbjct: 521 GGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRG 580
Query: 312 GSGGYYGQGGMSGGGWRGMY 331
GSGG +G G GG G Y
Sbjct: 581 GSGGSHGGGSGFGGESGGSY 600
Score = 61.2 bits (147), Expect = 1e-09
Identities = 38/85 (44%), Positives = 41/85 (48%), Gaps = 2/85 (2%)
Query: 248 IELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGG-YGSVGRMGMGNNYSGGYGTPDGLGGY 306
IE + N GG SG G G G GG YG R G G +Y GG G+ G GG
Sbjct: 451 IETYHNLLEGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGG-GSGGGYGGG 509
Query: 307 GRGGGGSGGYYGQGGMSGGGWRGMY 331
GGSGG YG G SGGG G Y
Sbjct: 510 SGSRGGSGGSYGGGSGSGGGSGGGY 534
Score = 60.1 bits (144), Expect = 3e-09
Identities = 38/76 (50%), Positives = 38/76 (50%), Gaps = 3/76 (3%)
Query: 257 GGGSGMG-GSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGG 315
GGGSG G G G G G G GG GS G G G Y GG G G G GGSGG
Sbjct: 499 GGGSGGGYGGGSGSRGGSGGSYGGGSGSGG--GSGGGYGGGSGGGHSGGSGGGHSGGSGG 556
Query: 316 YYGQGGMSGGGWRGMY 331
YG G SGGG G Y
Sbjct: 557 NYGGGSGSGGGSGGGY 572
Score = 59.7 bits (143), Expect = 4e-09
Identities = 32/72 (44%), Positives = 40/72 (55%), Gaps = 4/72 (5%)
Query: 251 FLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGG 310
F S+ GGG G G G GG G + GG+G G G + GGYG+ G GG+G G
Sbjct: 81 FSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGS--GFGGFGGFG 138
Query: 311 GGSGGYYGQGGM 322
GG+GG G GG+
Sbjct: 139 GGAGG--GDGGI 148
Score = 58.5 bits (140), Expect = 8e-09
Identities = 40/76 (52%), Positives = 41/76 (53%), Gaps = 9/76 (11%)
Query: 258 GGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGG-YGRG---GGGS 313
G G GGSG G YGR GG S G G G Y GG G+ G GG YG G GGGS
Sbjct: 474 GLGGRGGSG-GSYGRGSRGGSGG--SYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGS 530
Query: 314 GGYYGQGGMSGGGWRG 329
GG G GG SGGG G
Sbjct: 531 GG--GYGGGSGGGHSG 544
Score = 53.9 bits (128), Expect = 2e-07
Identities = 35/77 (45%), Positives = 40/77 (51%), Gaps = 13/77 (16%)
Query: 257 GGGSGMGGSGMGGYGR---DGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGS 313
GGGSG G G YG G + GGYG G G +SGG G GG+ G GG+
Sbjct: 507 GGGSGSRGGSGGSYGGGSGSGGGSGGGYGG----GSGGGHSGGSG-----GGHSGGSGGN 557
Query: 314 -GGYYGQGGMSGGGWRG 329
GG G GG SGGG+ G
Sbjct: 558 YGGGSGSGGGSGGGYGG 574
Score = 53.9 bits (128), Expect = 2e-07
Identities = 37/81 (45%), Positives = 39/81 (48%), Gaps = 7/81 (8%)
Query: 254 STPGGGSGMG---GSGMGGYGRDGMDNQGGYGS--VGRMGMGNNYSGGYGTPDGLGGYGR 308
S GGGSG G GSG G G G + GG G G G G GGYG G G G
Sbjct: 524 SGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYG--GGSGSRGG 581
Query: 309 GGGGSGGYYGQGGMSGGGWRG 329
GG GG G GG SGG + G
Sbjct: 582 SGGSHGGGSGFGGESGGSYGG 602
Score = 53.1 bits (126), Expect = 3e-07
Identities = 36/77 (46%), Positives = 39/77 (50%), Gaps = 10/77 (12%)
Query: 257 GGGSGMG------GSGMGGYGRD-GMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRG 309
GGGSG G G G GG R G + GGY S G G G + GG G G GGYG G
Sbjct: 74 GGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSG--GFGGGFGGGSGGGFG-GGYGSG 130
Query: 310 GGGSGGYYGQGGMSGGG 326
GG GG+ G G GG
Sbjct: 131 FGGFGGFGGGAGGGDGG 147
Score = 50.4 bits (119), Expect = 2e-06
Identities = 32/71 (45%), Positives = 35/71 (49%), Gaps = 8/71 (11%)
Query: 257 GGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGY 316
GGG G GGS Y R + GG G GR + Y GG GRGGGGS GY
Sbjct: 19 GGGLGSGGSIRSSYSR--FSSSGGGGGGGRFSSSSGYGGGSSRV-----CGRGGGGSFGY 71
Query: 317 YGQGGMSGGGW 327
GG SGGG+
Sbjct: 72 -SYGGGSGGGF 81
Score = 50.1 bits (118), Expect = 3e-06
Identities = 33/82 (40%), Positives = 36/82 (43%), Gaps = 10/82 (12%)
Query: 258 GGSGMGGSGMGGYGRDG---MDNQGGYGSVGRMGMGNNYSGGYGTPDGLG-----GYGRG 309
GG G GG G GG R + GG G GR + Y GG G G GY G
Sbjct: 15 GGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYG 74
Query: 310 GGGSGGYYGQ--GGMSGGGWRG 329
GG GG+ GG GGG RG
Sbjct: 75 GGSGGGFSASSLGGGFGGGSRG 96
Score = 50.1 bits (118), Expect = 3e-06
Identities = 38/84 (45%), Positives = 41/84 (48%), Gaps = 17/84 (20%)
Query: 253 NSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGG 312
+S GG GGSG G YG GG GS G G G Y GG G+ G GG GG G
Sbjct: 542 HSGGSGGGHSGGSG-GNYG-------GGSGSGG--GSGGGYGGGSGSRGGSGGSHGGGSG 591
Query: 313 ----SGGYYGQG---GMSGGGWRG 329
SGG YG G SGGG+ G
Sbjct: 592 FGGESGGSYGGGEEASGSGGGYGG 615
Score = 49.3 bits (116), Expect = 5e-06
Identities = 31/76 (40%), Positives = 37/76 (48%), Gaps = 7/76 (9%)
Query: 257 GGGS---GMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGS 313
GGGS GG GG+ + GG+G G G G GGY + G GG G GGG
Sbjct: 65 GGGSFGYSYGGGSGGGFSASSLG--GGFGG-GSRGFGGASGGGYSSSGGFGG-GFGGGSG 120
Query: 314 GGYYGQGGMSGGGWRG 329
GG+ G G GG+ G
Sbjct: 121 GGFGGGYGSGFGGFGG 136
Score = 48.9 bits (115), Expect = 6e-06
Identities = 33/69 (47%), Positives = 35/69 (50%), Gaps = 10/69 (14%)
Query: 257 GGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGG-YGRGGGGSGG 315
GGGSG GG GGYG GG GS G G G ++ GG G GG YG G SG
Sbjct: 559 GGGSGSGGGSGGGYG-------GGSGSRG--GSGGSHGGGSGFGGESGGSYGGGEEASGS 609
Query: 316 YYGQGGMSG 324
G GG SG
Sbjct: 610 GGGYGGGSG 618
Score = 48.1 bits (113), Expect = 1e-05
Identities = 34/84 (40%), Positives = 40/84 (47%), Gaps = 10/84 (11%)
Query: 254 STPGGGSGMG----GSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRG 309
S+ GGG G G SG GG G + +GG GS G G GG+ GG+G G
Sbjct: 36 SSSGGGGGGGRFSSSSGYGG-GSSRVCGRGGGGSFG-YSYGGGSGGGFSASSLGGGFGGG 93
Query: 310 ----GGGSGGYYGQGGMSGGGWRG 329
GG SGG Y G GGG+ G
Sbjct: 94 SRGFGGASGGGYSSSGGFGGGFGG 117
Score = 45.4 bits (106), Expect = 7e-05
Identities = 27/66 (40%), Positives = 27/66 (40%), Gaps = 5/66 (7%)
Query: 119 GGRGGYYGAGR-----GSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDAS 173
GG GG YG G GSYGG GGY G G G GG GG G S
Sbjct: 479 GGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGS 538
Query: 174 SGFHGG 179
G H G
Sbjct: 539 GGGHSG 544
Score = 45.4 bits (106), Expect = 7e-05
Identities = 28/64 (43%), Positives = 33/64 (51%), Gaps = 6/64 (9%)
Query: 119 GGRGGYYGAGRGSYGGFD-DYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFH 177
GG GG YG G GS GG YGG + G G+ G G G GG GG+G SG
Sbjct: 500 GGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGG-----GYGGGSGGGHSGGSGGGHSGGS 554
Query: 178 GGHF 181
GG++
Sbjct: 555 GGNY 558
Score = 42.0 bits (97), Expect = 8e-04
Identities = 27/61 (44%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
Query: 254 STPGGGSGMG-GSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGG 312
S GGGSG G G G G G G + GG G G G +Y GG GGYG G G
Sbjct: 562 SGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGE--SGGSYGGGEEASGSGGGYGGGSGK 619
Query: 313 S 313
S
Sbjct: 620 S 620
Score = 41.2 bits (95), Expect = 0.001
Identities = 30/74 (40%), Positives = 33/74 (44%), Gaps = 3/74 (4%)
Query: 108 GQRPGPYDRPI-GGRGGYYGAGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGY 166
G G Y R GG GG YG G GS GG+ G G+ G G G GG+G
Sbjct: 479 GGSGGSYGRGSRGGSGGSYGGG-GSGGGYGGGSGSRGGSGGSYGGGSGSGGGSG-GGYGG 536
Query: 167 GGAGDASSGFHGGH 180
G G S G GGH
Sbjct: 537 GSGGGHSGGSGGGH 550
Score = 41.2 bits (95), Expect = 0.001
Identities = 24/69 (34%), Positives = 31/69 (44%), Gaps = 7/69 (10%)
Query: 119 GGRGGYYGAGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYG-------GAGD 171
G GG+ G G+YGG GG + GYG G GG G+G G G+
Sbjct: 545 GSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGE 604
Query: 172 ASSGFHGGH 180
+SG GG+
Sbjct: 605 EASGSGGGY 613
Score = 40.4 bits (93), Expect = 0.002
Identities = 27/63 (42%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Query: 119 GGRGGYYGAGRGSYGGFDDYGGY-NNYGYGNDGFDDRMRDGRGMGGHGYG-GAGDASSGF 176
GG GG YG G GS GG GGY G G+ G G G +G G G+G S G
Sbjct: 514 GGSGGSYGGGSGSGGG--SGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGG 571
Query: 177 HGG 179
+GG
Sbjct: 572 YGG 574
Score = 39.3 bits (90), Expect = 0.005
Identities = 23/61 (37%), Positives = 26/61 (42%)
Query: 119 GGRGGYYGAGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHG 178
GG GG YG G G GG++ GN G G G G G G+ S G HG
Sbjct: 528 GGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHG 587
Query: 179 G 179
G
Sbjct: 588 G 588
Score = 38.1 bits (87), Expect = 0.011
Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 1/56 (1%)
Query: 119 GGRGGYYGAGRGSYGGFD-DYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDAS 173
GG GG YG G GS GG +GG + +G + G + G GG GG+G +S
Sbjct: 566 GGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSS 621
Score = 37.4 bits (85), Expect = 0.019
Identities = 24/64 (37%), Positives = 29/64 (45%), Gaps = 2/64 (3%)
Query: 119 GGRGGY-YGAGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDG-RGMGGHGYGGAGDASSGF 176
GG G + Y G GS GGF +G G+ GF G GG G G G + GF
Sbjct: 64 GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGF 123
Query: 177 HGGH 180
GG+
Sbjct: 124 GGGY 127
Score = 35.8 bits (81), Expect = 0.054
Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 10/61 (16%)
Query: 120 GRGGYYGAGRGSYGGF-DDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHG 178
G GG G G S GGF +GG + G+G G G G G+GG G + G G
Sbjct: 96 GFGGASGGGYSSSGGFGGGFGGGSGGGFGG---------GYGSGFGGFGGFGGGAGGGDG 146
Query: 179 G 179
G
Sbjct: 147 G 147
Score = 34.7 bits (78), Expect = 0.12
Identities = 28/75 (37%), Positives = 33/75 (44%), Gaps = 12/75 (16%)
Query: 119 GGRGGYYGAGRGSYGGFDDY-----GGYNNYGYGND---GFD-DRMRDGRGMGGHGYGGA 169
GG GG + + G GG GG Y YG GF + G G G G+GGA
Sbjct: 41 GGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGA 100
Query: 170 ---GDASSGFHGGHF 181
G +SSG GG F
Sbjct: 101 SGGGYSSSGGFGGGF 115
Score = 34.3 bits (77), Expect = 0.16
Identities = 23/66 (34%), Positives = 29/66 (43%), Gaps = 12/66 (18%)
Query: 119 GGRGGYYGA---GRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSG 175
GG GG + A G G GG +GG + GY + G G GG GG+G G
Sbjct: 75 GGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSG---------GFGGGFGGGSGGGFGG 125
Query: 176 FHGGHF 181
+G F
Sbjct: 126 GYGSGF 131
Score = 33.5 bits (75), Expect = 0.27
Identities = 25/67 (37%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Query: 119 GGRGGYY--GAGRGSYGGF-DDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGA---GDA 172
GG GG + G+G G GG +YGG + G G+ G RG G +GG G
Sbjct: 536 GGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGE 595
Query: 173 SSGFHGG 179
S G +GG
Sbjct: 596 SGGSYGG 602
Score = 33.1 bits (74), Expect = 0.35
Identities = 24/67 (35%), Positives = 28/67 (41%), Gaps = 11/67 (16%)
Query: 108 GQRPGPYDRPIGGRGGYYGAGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYG 167
G G Y G RGG GS+GG +GG + YG + G GG GYG
Sbjct: 566 GGSGGGYGGGSGSRGG----SGGSHGGGSGFGGESGGSYGGG------EEASGSGG-GYG 614
Query: 168 GAGDASS 174
G SS
Sbjct: 615 GGSGKSS 621
Score = 32.3 bits (72), Expect = 0.60
Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 2/63 (3%)
Query: 119 GGRGGYYGAGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGD--ASSGF 176
GG+ + +G G G G +YG G+ G G G GG GG+G S G
Sbjct: 460 GGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGS 519
Query: 177 HGG 179
+GG
Sbjct: 520 YGG 522
Score = 31.6 bits (70), Expect = 1.0
Identities = 24/68 (35%), Positives = 29/68 (42%), Gaps = 12/68 (17%)
Query: 119 GGRGGYYGAG---RGSYGGFDDYGG-------YNNYGYGNDGFDDRMRDGRGMGGHGYGG 168
GG GG G+G R SY F GG ++ GYG G R+ G G GY
Sbjct: 16 GGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYG--GGSSRVCGRGGGGSFGYSY 73
Query: 169 AGDASSGF 176
G + GF
Sbjct: 74 GGGSGGGF 81
Score = 30.8 bits (68), Expect = 1.7
Identities = 19/57 (33%), Positives = 24/57 (42%), Gaps = 2/57 (3%)
Query: 98 GFYDPPRRLLGQRPGPYDRPIGGRGGYYGAGRGSYGG--FDDYGGYNNYGYGNDGFD 152
GF R G G Y G GG+ G G +GG +GG+ +G G G D
Sbjct: 89 GFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGD 145
Score = 30.0 bits (66), Expect = 3.0
Identities = 15/30 (50%), Positives = 18/30 (60%), Gaps = 1/30 (3%)
Query: 119 GGRGGYYGAGRGS-YGGFDDYGGYNNYGYG 147
GG GG +G G GS +GGF +GG G G
Sbjct: 117 GGSGGGFGGGYGSGFGGFGGFGGGAGGGDG 146
Score = 29.3 bits (64), Expect = 5.1
Identities = 13/27 (48%), Positives = 16/27 (59%)
Query: 119 GGRGGYYGAGRGSYGGFDDYGGYNNYG 145
GG GG YG+G G +GGF G + G
Sbjct: 121 GGFGGGYGSGFGGFGGFGGGAGGGDGG 147
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 62.4 bits (150), Expect = 5e-10
Identities = 38/72 (52%), Positives = 39/72 (54%), Gaps = 5/72 (6%)
Query: 255 TPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYG-TPDGLGGYGRGGGGS 313
T GGG G GGSG GG G G GG G G G YSGG G + G GG GGGG
Sbjct: 19 TSGGGGGGGGSGGGGCGFFGGGGSGG----GSSGSGCGYSGGGGYSGGGCGGGSSGGGGG 74
Query: 314 GGYYGQGGMSGG 325
GG G GG SGG
Sbjct: 75 GGIGGCGGGSGG 86
Score = 56.6 bits (135), Expect = 3e-08
Identities = 62/216 (28%), Positives = 75/216 (34%), Gaps = 38/216 (17%)
Query: 119 GGRGGYYGAGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAGDASSGFHG 178
GG GG G G G +GG GG + G G G GG+ GG G SSG G
Sbjct: 24 GGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGG----------GGYSGGGCGGGSSGGGG 73
Query: 179 GHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHEDAVAAMSK 238
G + G + + G ++G F + S
Sbjct: 74 GGGIGGCGGGSGGS-----------------VKYSGGGGSSGGGSGCFSSGGGGSGCFSS 116
Query: 239 DKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQG----GYGSVGRMGMGNNYS 294
F S+ GGGS GGSG G G Q YG V G S
Sbjct: 117 GGGGSSGGGSGCF--SSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGS 174
Query: 295 GGYGTPDGLG---GYGRGGGGSGGYYGQGGMSGGGW 327
G + + G G GY GG G GG G G SG G+
Sbjct: 175 GCFSSGGGGGSVCGYSGGGSGCGG--GSSGGSGSGY 208
Score = 53.9 bits (128), Expect = 2e-07
Identities = 35/82 (42%), Positives = 41/82 (50%), Gaps = 9/82 (10%)
Query: 259 GSGMGGSGMGGYGRDGM----DNQGGYGSVGRMGMGN----NYSGGYGTPDGLGG-YGRG 309
GSG G SG GGY G GG G +G G G+ YSGG G+ G G + G
Sbjct: 48 GSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSG 107
Query: 310 GGGSGGYYGQGGMSGGGWRGMY 331
GGGSG + GG S GG G +
Sbjct: 108 GGGSGCFSSGGGGSSGGGSGCF 129
Score = 51.2 bits (121), Expect = 1e-06
Identities = 62/216 (28%), Positives = 74/216 (34%), Gaps = 53/216 (24%)
Query: 120 GRGGYYGAGRGSY---GGFDDYGGYNNYGYGNDGFDDRMRD-----GRGMGGHGYGGAGD 171
G GG G G G + GG GG + G GF + G GG GG+G
Sbjct: 117 GGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGC 176
Query: 172 ASSGFHGGHFVHMRGLPFRATENDIANFFSPLNPIRVHIDIGADGRATGEADVEFVTHED 231
SSG GG G G G ++G + +V+ +
Sbjct: 177 FSSGGGGGSVCGYSGG-----------------------GSGCGGGSSGGSGSGYVSSQQ 213
Query: 232 AVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGN 291
+ P G G SG GG G G + GG G G G G
Sbjct: 214 VTQT-----------------SCAPQPSYGGGSSGGGGSGGSGCFSSGGGG--GSSGCGG 254
Query: 292 NYSG-GYGTPDGLGGYGRGGGGSGGYYGQGGMSGGG 326
SG G G GG GGG SGG G GG S GG
Sbjct: 255 GSSGIGSGCIISGGGSVCGGGSSGG--GGGGSSVGG 288
Score = 50.1 bits (118), Expect = 3e-06
Identities = 34/84 (40%), Positives = 37/84 (44%), Gaps = 9/84 (10%)
Query: 257 GGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDG---------LGGYG 307
GGG G G SG GG G G G GSV G G + GG G GG G
Sbjct: 61 GGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGG 120
Query: 308 RGGGGSGGYYGQGGMSGGGWRGMY 331
GGGSG + GG S GG G +
Sbjct: 121 SSGGGSGCFSSGGGGSSGGGSGCF 144
Score = 45.1 bits (105), Expect = 9e-05
Identities = 40/104 (38%), Positives = 46/104 (44%), Gaps = 27/104 (25%)
Query: 253 NSTPGGGSGMGGSGMGG-----YGRDGMDNQGGYG--SVGRMGMGNNYSGGYGTPDG--- 302
+S GGG G+GG G G Y G + GG G S G G G SGG G+ G
Sbjct: 68 SSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSG 127
Query: 303 ---LGGYGRGGGGS-------GGYYGQ-------GGMSGGGWRG 329
GG G GGGS GG+ GQ GG+S GG G
Sbjct: 128 CFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSG 171
Score = 43.9 bits (102), Expect = 2e-04
Identities = 34/93 (36%), Positives = 36/93 (38%), Gaps = 20/93 (21%)
Query: 257 GGGSGMGGSGMGGYGRDGMDNQ---------------GGYGSVGRMGMGNNYSGGYGTPD 301
GGGSG GG GG G + +Q G G G G G SGG G
Sbjct: 191 GGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSS 250
Query: 302 GLGGYGRGGG-----GSGGYYGQGGMSGGGWRG 329
G GG G G GG GG SGGG G
Sbjct: 251 GCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGG 283
>gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapiens]
Length = 1270
Score = 61.6 bits (148), Expect = 9e-10
Identities = 38/87 (43%), Positives = 41/87 (47%), Gaps = 12/87 (13%)
Query: 257 GGGSGMGGSGMGGYGRDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLG--GYGRGG---- 310
G G GGS G G G + GGYGS G G N++ GYG G G G RGG
Sbjct: 1170 GSGYRRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGN 1229
Query: 311 ------GGSGGYYGQGGMSGGGWRGMY 331
G SGGY G GG GG RG Y
Sbjct: 1230 SGGDYRGPSGGYRGSGGFQRGGGRGAY 1256
Score = 53.9 bits (128), Expect = 2e-07
Identities = 34/84 (40%), Positives = 38/84 (45%), Gaps = 15/84 (17%)
Query: 257 GGGSGMGGSGMGGYGRDGMDNQGGYGS--------VGRMGMGNNYSGGYGTPDG----LG 304
GGG GG G GGYG + GYG+ V R G N G Y P G G
Sbjct: 1186 GGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSG 1245
Query: 305 GYGRGGGGSG---GYYGQGGMSGG 325
G+ RGGG GY+GQG GG
Sbjct: 1246 GFQRGGGRGAYGTGYFGQGRGGGG 1269
Score = 44.3 bits (103), Expect = 2e-04
Identities = 45/136 (33%), Positives = 56/136 (41%), Gaps = 7/136 (5%)
Query: 55 RSTGEAFVQFASKEIAE-NALGKHKERIGHRYIEIFRSSRSEIKGFYDPPRRLLGQRP-- 111
R+ EA V +K+ A + L ER+ + +I R S + I R G RP
Sbjct: 1104 RAAMEALVVEVTKQPAIISQLDPVNERMLNMIRQISRPSAAGINLMIGSTRYGDGPRPPK 1163
Query: 112 -GPYDRPIGGRGGYYGAGRGSYGGFDDYGGYNNYGYGNDGFDDRMRDGRGMGGHGYGGAG 170
YD G R G G YGG GGY + GYG R G G+GG GY G
Sbjct: 1164 MARYDNGSGYRRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVGG-GYRGV- 1221
Query: 171 DASSGFHGGHFVHMRG 186
+ GF G RG
Sbjct: 1222 -SRGGFRGNSGGDYRG 1236
Score = 37.0 bits (84), Expect = 0.024
Identities = 42/133 (31%), Positives = 51/133 (38%), Gaps = 34/133 (25%)
Query: 217 RATGEADVEFVTHEDAVAAMSKDKNNMQHRYIELFLNSTPGGGSGMGGSGMGGYG----- 271
RA EA V VT + A+ + N I + G + M GS G G
Sbjct: 1104 RAAMEALVVEVTKQPAIISQLDPVNERMLNMIRQISRPSAAGINLMIGSTRYGDGPRPPK 1163
Query: 272 RDGMDNQGGYGSVGRMGMGNNYSGGYGTPDGLGGYGRGGGGSGGYYGQGGMS-------- 323
DN GY R G G++YSGG G GGG S G YG GG
Sbjct: 1164 MARYDNGSGY----RRG-GSSYSGG----------GYGGGYSSGGYGSGGYGGSANSFRA 1208
Query: 324 ------GGGWRGM 330
GGG+RG+
Sbjct: 1209 GYGAGVGGGYRGV 1221
Score = 31.2 bits (69), Expect = 1.3
Identities = 23/73 (31%), Positives = 28/73 (38%), Gaps = 22/73 (30%)
Query: 114 YDRPIGG------RGGYYGAGRGSY----GGFDDYGGYNNYGYGNDGFDDRMRDGRGMGG 163
Y +GG RGG+ G G Y GG+ GG+ G GRG G
Sbjct: 1210 YGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGG------------GRGAYG 1257
Query: 164 HGYGGAGDASSGF 176
GY G G G+
Sbjct: 1258 TGYFGQGRGGGGY 1270
Score = 29.3 bits (64), Expect = 5.1
Identities = 17/32 (53%), Positives = 17/32 (53%), Gaps = 1/32 (3%)
Query: 301 DGLGGYGRGGGG-SGGYYGQGGMSGGGWRGMY 331
D GY RGG SGG YG G SGG G Y
Sbjct: 1168 DNGSGYRRGGSSYSGGGYGGGYSSGGYGSGGY 1199
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.144 0.455
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,240,675
Number of Sequences: 37866
Number of extensions: 966953
Number of successful extensions: 16391
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 271
Number of HSP's successfully gapped in prelim test: 207
Number of HSP's that attempted gapping in prelim test: 4868
Number of HSP's gapped (non-prelim): 5081
length of query: 331
length of database: 18,247,518
effective HSP length: 103
effective length of query: 228
effective length of database: 14,347,320
effective search space: 3271188960
effective search space used: 3271188960
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.