Search of human proteins with 13994276

Search of human proteins with 13994276

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13994276 marapsin [Homo sapiens]
         (290 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13994276 marapsin [Homo sapiens]                                   609   e-175
gi|11545839 protease, serine, 22 [Homo sapiens]                       285   3e-77
gi|117956391 protease, serine, 33 [Homo sapiens]                      254   5e-68
gi|4506153 prostasin preproprotein [Homo sapiens]                     238   6e-63
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]      234   7e-62
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]            227   8e-60
gi|68508970 tryptase beta 2 precursor [Homo sapiens]                  226   2e-59
gi|21614531 testisin isoform 2 [Homo sapiens]                         219   2e-57
gi|5803197 testisin isoform 1 [Homo sapiens]                          218   4e-57
gi|58218970 protease, serine, 36 [Homo sapiens]                       216   2e-56
gi|23957702 transmembrane protease, serine 6 [Homo sapiens]           208   4e-54
gi|34098976 marapsin 2 [Homo sapiens]                                 206   2e-53
gi|33667063 transmembrane protease, serine 9 [Homo sapiens]           204   7e-53
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]             204   1e-52
gi|148806900 epidermis-specific serine protease-like protein [Ho...   203   2e-52
gi|33695155 hepsin [Homo sapiens]                                     195   3e-50
gi|4504481 hepsin [Homo sapiens]                                      195   3e-50
gi|21614533 testisin isoform 3 [Homo sapiens]                         192   3e-49
gi|4505881 plasminogen [Homo sapiens]                                 191   6e-49
gi|205360905 testis-specific serine protease 1 [Homo sapiens]         188   4e-48
gi|170932492 transmembrane protease, serine 5 [Homo sapiens]          188   5e-48
gi|4503627 coagulation factor XI precursor [Homo sapiens]             186   2e-47
gi|116256363 transmembrane protease, serine 13 [Homo sapiens]         183   1e-46
gi|40254871 transmembrane protease, serine 11E [Homo sapiens]         182   4e-46
gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]       182   4e-46
gi|222831592 transmembrane protease, serine 7 [Homo sapiens]          181   7e-46
gi|11415040 matriptase [Homo sapiens]                                 181   7e-46
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa...   180   1e-45
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa...   180   1e-45
gi|187761337 transmembrane protease, serine 11B [Homo sapiens]        180   1e-45

>gi|13994276 marapsin [Homo sapiens]
          Length = 290

 Score =  609 bits (1571), Expect = e-175
 Identities = 290/290 (100%), Positives = 290/290 (100%)

Query: 1   MRRPAAVPLLLLLCFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFC 60
           MRRPAAVPLLLLLCFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFC
Sbjct: 1   MRRPAAVPLLLLLCFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFC 60

Query: 61  GGSLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTA 120
           GGSLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTA
Sbjct: 61  GGSLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTA 120

Query: 121 SSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQK 180
           SSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQK
Sbjct: 121 SSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQK 180

Query: 181 LAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQS 240
           LAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQS
Sbjct: 181 LAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQS 240

Query: 241 WLQAGVISWGEGCARQNRPGVYIRVTAHHNWIHRIIPKLQFQPARLGGQK 290
           WLQAGVISWGEGCARQNRPGVYIRVTAHHNWIHRIIPKLQFQPARLGGQK
Sbjct: 241 WLQAGVISWGEGCARQNRPGVYIRVTAHHNWIHRIIPKLQFQPARLGGQK 290


>gi|11545839 protease, serine, 22 [Homo sapiens]
          Length = 317

 Score =  285 bits (730), Expect = 3e-77
 Identities = 139/285 (48%), Positives = 188/285 (65%), Gaps = 10/285 (3%)

Query: 10  LLLLC----FGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLI 65
           LLLL       + R     ACG+P+ LNR+VGG+D+ + EWPW VSIQ+NG+H C GSL+
Sbjct: 21  LLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLL 80

Query: 66  AEQWVLTAAHCFR-NTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASS-A 123
             +WV+TAAHCF+ N ++  L+ VLLGA QL  PG  +    V  VE +P+Y     + A
Sbjct: 81  TSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWKEGACA 140

Query: 124 DVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAV 183
           D+ALV LE  + F+  +LP+CLPD S+      +CW++GWGS  +   LP P+ LQKL V
Sbjct: 141 DIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKV 200

Query: 184 PIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQ 243
           PIID+  C+ LY +    G     I  DMLCAG+ EG++DAC GDSGGPL+C V  +WL 
Sbjct: 201 PIIDSEVCSHLYWRGAGQG----PITEDMLCAGYLEGERDACLGDSGGPLMCQVDGAWLL 256

Query: 244 AGVISWGEGCARQNRPGVYIRVTAHHNWIHRIIPKLQFQPARLGG 288
           AG+ISWGEGCA +NRPGVYI ++AH +W+ +I+  +Q +    GG
Sbjct: 257 AGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGRAQGG 301


>gi|117956391 protease, serine, 33 [Homo sapiens]
          Length = 280

 Score =  254 bits (650), Expect = 5e-68
 Identities = 128/274 (46%), Positives = 169/274 (61%), Gaps = 2/274 (0%)

Query: 1   MRRPAAVPLLLLLCFGSQ--RAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSH 58
           MR  + + +LLLL  G+   + + + ACG+PRM +R+VGG+D ++GEWPWQ SIQ  G+H
Sbjct: 1   MRGVSCLQVLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAH 60

Query: 59  FCGGSLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQG 118
            CGGSLIA QWVLTAAHCF   +  + Y+V LGA +L    P  +   VR+V   P Y  
Sbjct: 61  VCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSE 120

Query: 119 TASSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRIL 178
             +  D+AL++L  PVP +  + PVCLP P      G  C VTGWGS      LPE R L
Sbjct: 121 DGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPL 180

Query: 179 QKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVG 238
           Q + VP++D+  C+ LY    +     + +    LCAG+ +G KDAC+GDSGGPL CL  
Sbjct: 181 QGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQS 240

Query: 239 QSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWI 272
            SW+  GV+SWG+GCA  NRPGVY  V  +  WI
Sbjct: 241 GSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWI 274


>gi|4506153 prostasin preproprotein [Homo sapiens]
          Length = 343

 Score =  238 bits (606), Expect = 6e-63
 Identities = 119/278 (42%), Positives = 164/278 (58%), Gaps = 5/278 (1%)

Query: 6   AVPLLL---LLCFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGG 62
           AV +LL   LL  G+    A   CG      R+ GG     G+WPWQVSI   G H CGG
Sbjct: 14  AVAILLYLGLLRSGTGAEGAEAPCGVAPQA-RITGGSSAVAGQWPWQVSITYEGVHVCGG 72

Query: 63  SLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASS 122
           SL++EQWVL+AAHCF +      Y+V LGA QL      A  + ++ +  +P Y    S 
Sbjct: 73  SLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQ 132

Query: 123 ADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLA 182
            D+AL++L  P+ F+ YI P+CLP  +  F  G++C VTGWG  +    L  P+ LQ+L 
Sbjct: 133 GDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLE 192

Query: 183 VPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWL 242
           VP+I    CN LY+ D +   +P  ++ DM+CAG+ EG KDAC+GDSGGPL C V   W 
Sbjct: 193 VPLISRETCNCLYNIDAK-PEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWY 251

Query: 243 QAGVISWGEGCARQNRPGVYIRVTAHHNWIHRIIPKLQ 280
             G++SWG+ C  +NRPGVY   +++ +WI   + +LQ
Sbjct: 252 LTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQ 289


>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
          Length = 321

 Score =  234 bits (597), Expect = 7e-62
 Identities = 129/273 (47%), Positives = 165/273 (60%), Gaps = 17/273 (6%)

Query: 9   LLLLLCFGSQRAKAATACGRPRMLN---RMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLI 65
           LLLL   G         CGRP++ +   R+VGG     G WPWQ S++    H CGGSL+
Sbjct: 9   LLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLL 68

Query: 66  AEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQV--ESNPLYQGTASSA 123
           + QWVLTAAHCF  +  +S YQV LG  ++    PH  ++ VRQ+   S+P  Q   +S 
Sbjct: 69  SPQWVLTAAHCFSGSLNSSDYQVHLGELEITL-SPH--FSTVRQIILHSSPSGQ-PGTSG 124

Query: 124 DVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAV 183
           D+ALVEL  PV  ++ ILPVCLP+ S  F  G+ CWVTGWG   E + LP P  L+++ V
Sbjct: 125 DIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKV 184

Query: 184 PIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQ 243
            ++DT  C   Y      G     ++ DMLCA    G  DAC+ DSGGPLVC V  +W+Q
Sbjct: 185 SVVDTETCRRDYP-----GPGGSILQPDMLCA---RGPGDACQDDSGGPLVCQVNGAWVQ 236

Query: 244 AGVISWGEGCARQNRPGVYIRVTAHHNWIHRII 276
           AG++SWGEGC R NRPGVY RV A+ NWI R I
Sbjct: 237 AGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHI 269


>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
          Length = 275

 Score =  227 bits (579), Expect = 8e-60
 Identities = 120/274 (43%), Positives = 166/274 (60%), Gaps = 9/274 (3%)

Query: 9   LLLLLCFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGS---HFCGGSLI 65
           LLL L   + RA AA A G+      +VGGQ+    +WPWQVS++ +G    HFCGGSLI
Sbjct: 5   LLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLI 64

Query: 66  AEQWVLTAAHCFR-NTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSAD 124
             QWVLTAAHC   +  + +  +V L  + L           V ++  +P +      AD
Sbjct: 65  HPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQD---QLLPVSRIIVHPQFYTAQIGAD 121

Query: 125 VALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVP 184
           +AL+ELE PV  ++++  V LP  S  F  GM CWVTGWG    ++ LP P  L+++ VP
Sbjct: 122 IALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVP 181

Query: 185 IIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQA 244
           I++   C+  Y      G   + +++DMLCAG    ++D+C+GDSGGPLVC V  +WLQA
Sbjct: 182 IMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQA 239

Query: 245 GVISWGEGCARQNRPGVYIRVTAHHNWIHRIIPK 278
           GV+SWGEGCA+ NRPG+Y RVT + +WIH  +PK
Sbjct: 240 GVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPK 273


>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
          Length = 275

 Score =  226 bits (576), Expect = 2e-59
 Identities = 120/274 (43%), Positives = 165/274 (60%), Gaps = 9/274 (3%)

Query: 9   LLLLLCFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQ---RNGSHFCGGSLI 65
           LLL L   + RA AA A G+      +VGGQ+    +WPWQVS++   R   HFCGGSLI
Sbjct: 5   LLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLI 64

Query: 66  AEQWVLTAAHCFR-NTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSAD 124
             QWVLTAAHC   +  + +  +V L  + L           V ++  +P +      AD
Sbjct: 65  HPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQD---QLLPVSRIIVHPQFYTAQIGAD 121

Query: 125 VALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVP 184
           +AL+ELE PV  ++++  V LP  S  F  GM CWVTGWG    ++ LP P  L+++ VP
Sbjct: 122 IALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVP 181

Query: 185 IIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQA 244
           I++   C+  Y      G   + +++DMLCAG    ++D+C+GDSGGPLVC V  +WLQA
Sbjct: 182 IMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NTRRDSCQGDSGGPLVCKVNGTWLQA 239

Query: 245 GVISWGEGCARQNRPGVYIRVTAHHNWIHRIIPK 278
           GV+SWGEGCA+ NRPG+Y RVT + +WIH  +PK
Sbjct: 240 GVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPK 273


>gi|21614531 testisin isoform 2 [Homo sapiens]
          Length = 312

 Score =  219 bits (558), Expect = 2e-57
 Identities = 121/285 (42%), Positives = 166/285 (58%), Gaps = 16/285 (5%)

Query: 3   RPAAVPLLLLLCFGSQRAKAATA------CGRPRMLNRMVGGQDTQEGEWPWQVSIQRNG 56
           R A +  LLL   G ++ ++  A      CGR  + +R+VGG+D + G WPWQ S++   
Sbjct: 4   RGALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWD 63

Query: 57  SHFCGGSLIAEQWVLTAAHCFR-NTSETSLYQVLLGARQLVQP--GPHAMYAR--VRQVE 111
           SH CG SL++ +W LTAAHCF  + S+ S + V  G    +       A Y R  V  + 
Sbjct: 64  SHVCGVSLLSHRWALTAAHCFETDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIY 123

Query: 112 SNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDL 171
            +P Y G  S  D+ALV+L APV +T +I P+CL   +  FE   +CWVTGWG   E++ 
Sbjct: 124 LSPRYLGN-SPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKEDEA 182

Query: 172 LPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGG 231
           LP P  LQ++ V II+   CN L+ K   + ++ K I  DM+CAG  +G KDAC GDSGG
Sbjct: 183 LPSPHTLQEVQVAIINNSMCNHLFLK---YSFR-KDIFGDMVCAGNAQGGKDACFGDSGG 238

Query: 232 PLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWIHRII 276
           PL C     W Q GV+SWG GC R NRPGVY  ++ H  WI +++
Sbjct: 239 PLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLM 283


>gi|5803197 testisin isoform 1 [Homo sapiens]
          Length = 314

 Score =  218 bits (556), Expect = 4e-57
 Identities = 121/287 (42%), Positives = 166/287 (57%), Gaps = 18/287 (6%)

Query: 3   RPAAVPLLLLLCFGSQRAKAATA------CGRPRMLNRMVGGQDTQEGEWPWQVSIQRNG 56
           R A +  LLL   G ++ ++  A      CGR  + +R+VGG+D + G WPWQ S++   
Sbjct: 4   RGALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWD 63

Query: 57  SHFCGGSLIAEQWVLTAAHCFR---NTSETSLYQVLLGARQLVQP--GPHAMYAR--VRQ 109
           SH CG SL++ +W LTAAHCF    + S+ S + V  G    +       A Y R  V  
Sbjct: 64  SHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSN 123

Query: 110 VESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEE 169
           +  +P Y G  S  D+ALV+L APV +T +I P+CL   +  FE   +CWVTGWG   E+
Sbjct: 124 IYLSPRYLGN-SPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKED 182

Query: 170 DLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDS 229
           + LP P  LQ++ V II+   CN L+ K   + ++ K I  DM+CAG  +G KDAC GDS
Sbjct: 183 EALPSPHTLQEVQVAIINNSMCNHLFLK---YSFR-KDIFGDMVCAGNAQGGKDACFGDS 238

Query: 230 GGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWIHRII 276
           GGPL C     W Q GV+SWG GC R NRPGVY  ++ H  WI +++
Sbjct: 239 GGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLM 285


>gi|58218970 protease, serine, 36 [Homo sapiens]
          Length = 855

 Score =  216 bits (550), Expect = 2e-56
 Identities = 113/264 (42%), Positives = 144/264 (54%), Gaps = 8/264 (3%)

Query: 26  CGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSE--- 82
           CGRP    R+VGG + Q G WPWQVS+   G H CGGSLIA  WVL+AAHCF        
Sbjct: 38  CGRPEPSARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEP 97

Query: 83  TSLYQVLLGARQLVQP--GPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYI 140
            + + VLLG      P  G H        V +N  Y      AD+AL+ L +P      +
Sbjct: 98  AAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPAN--YSQVELGADLALLRLASPASLGPAV 155

Query: 141 LPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTE 200
            PVCLP  S  F  G  CW TGWG   E D LP P +LQ++ + ++    C  LYS+   
Sbjct: 156 WPVCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGP 215

Query: 201 FGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPG 260
           F    + +   MLCAG+ EG++D C+GDSGGPLVC  G  W QAG+ S+G GC R+NRPG
Sbjct: 216 FNLTLQILPG-MLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRNRPG 274

Query: 261 VYIRVTAHHNWIHRIIPKLQFQPA 284
           V+  V  +  WI   +   +  PA
Sbjct: 275 VFTAVATYEAWIREQVMGSEPGPA 298



 Score = 90.9 bits (224), Expect = 1e-18
 Identities = 76/267 (28%), Positives = 115/267 (43%), Gaps = 18/267 (6%)

Query: 15  FGSQRAKAATACGRPRMLNRMVG----GQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWV 70
           F +Q  K  +    PR  N  +     G+  + G WPW+  +   GS  C G+L++E WV
Sbjct: 299 FPTQPQKTQSDPQEPREENCTIALPECGKAPRPGAWPWEAQVMVPGSRPCHGALVSESWV 358

Query: 71  LTAAHCFRN-TSETSLYQVLLGARQLVQPGPHA-MYARVRQVESNPLYQGTASSADVALV 128
           L  A CF +  S  S  + L   R L+   P A   AR+ Q E+        +++D+AL+
Sbjct: 359 LAPASCFLDPNSSDSPPRDLDAWRVLLPSRPRAERVARLVQHEN----ASWDNASDLALL 414

Query: 129 ELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDT 188
           +L  PV  +    PVCLP P   F  G  C +  WG   E  L P       L   ++  
Sbjct: 415 QLRTPVNLSAASRPVCLPHPEHYFLPGSRCRLARWGR-GEPALGPG----ALLEAELLGG 469

Query: 189 PKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVIS 248
             C+ LY +       P    + +  A  E+ +  +C  DS   L+C    +W  AG+  
Sbjct: 470 WWCHCLYGRQGAAVPLPGDPPHALCPAYQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRD 529

Query: 249 WGEGCARQNRPGVYIRVTAHHNWIHRI 275
           +  GC    RP  +  +  H  WI  +
Sbjct: 530 FPSGCL---RPRAFFPLQTHGPWISHV 553



 Score = 83.2 bits (204), Expect = 2e-16
 Identities = 69/242 (28%), Positives = 102/242 (42%), Gaps = 32/242 (13%)

Query: 46  WPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSL--YQVLLG-ARQLVQPGPHA 102
           WPW   +   G   C G L+A  WVL A HC      T++   +V LG A     P  H 
Sbjct: 601 WPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGHQ 660

Query: 103 MYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTG 162
           +    R V S  L Q       +AL+EL + V  +   LP+CL    +    G +CWV G
Sbjct: 661 V---SRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICLHPAGI--PPGASCWVLG 715

Query: 163 WGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKK 222
           W  P +       R+    AV I+    C+ LY      G  P       LC  + EG++
Sbjct: 716 WKEPQD-------RVPVAAAVSILTQRICDCLYQ-----GILPP----GTLCVLYAEGQE 759

Query: 223 DACKGDSGGPLVCLVGQ-SWLQAGVISWGEGCARQNRPGVYIRVTAHHNWIHRIIPKLQF 281
           + C+  S  PL+C + + SW+  G+       A Q    ++  +     WI + + +  F
Sbjct: 760 NRCEMTSAPPLLCQMTEGSWILVGM-------AVQGSRELFAAIGPEEAWISQTVGEANF 812

Query: 282 QP 283
            P
Sbjct: 813 LP 814


>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
          Length = 811

 Score =  208 bits (530), Expect = 4e-54
 Identities = 110/254 (43%), Positives = 153/254 (60%), Gaps = 14/254 (5%)

Query: 26  CGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTS--ET 83
           CG     +R+VGG  + EGEWPWQ S+Q  G H CGG+LIA++WV+TAAHCF+  S   T
Sbjct: 568 CGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMAST 627

Query: 84  SLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPV 143
            L+ V LG        P  +  +V ++  +P ++  +   DVAL++L+ PV  +  + PV
Sbjct: 628 VLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPV 687

Query: 144 CLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGY 203
           CLP  S  FE G++CW+TGWG+  E    P    LQK+ V +I    C+ +Y       Y
Sbjct: 688 CLPARSHFFEPGLHCWITGWGALREGG--PISNALQKVDVQLIPQDLCSEVYR------Y 739

Query: 204 QPKTIKNDMLCAGFEEGKKDACKGDSGGPLVC-LVGQSWLQAGVISWGEGCARQNRPGVY 262
           Q   +   MLCAG+ +GKKDAC+GDSGGPLVC  +   W  AG++SWG GC R N  GVY
Sbjct: 740 Q---VTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVY 796

Query: 263 IRVTAHHNWIHRII 276
            R+T   +WI +++
Sbjct: 797 TRITGVISWIQQVV 810


>gi|34098976 marapsin 2 [Homo sapiens]
          Length = 326

 Score =  206 bits (524), Expect = 2e-53
 Identities = 115/286 (40%), Positives = 152/286 (53%), Gaps = 27/286 (9%)

Query: 4   PAAVPLLLLLCFGSQRAKAA----------------TACGRPRMLNRMVGGQDTQEGEWP 47
           P+A+ LLLLL   +    AA                 ACGRP M  +++GG    E +WP
Sbjct: 13  PSALGLLLLLLVVAPPRVAALVHRQPENQGISLTGSVACGRPSMEGKILGGVPAPERKWP 72

Query: 48  WQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARV 107
           WQVS+   G H CGGS++ E WVL+AAHCF       +Y + +G   L   G H  +  V
Sbjct: 73  WQVSVHYAGLHVCGGSILNEYWVLSAAHCFHRDKNIKIYDMYVGLVNLRVAGNHTQWYEV 132

Query: 108 RQVESNPLYQ-GTASSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSP 166
            +V  +P Y+       DVALV+L+  + F+  +LPVCL  P V   T  NCW TGWG  
Sbjct: 133 NRVILHPTYEMYHPIGGDVALVQLKTRIVFSESVLPVCLATPEVNL-TSANCWATGWGLV 191

Query: 167 SEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACK 226
           S++    +   LQ++ +P+I  P C+LLY            I  DMLCAG     K  C+
Sbjct: 192 SKQGETSDE--LQEMQLPLILEPWCHLLYG-------HMSYIMPDMLCAGDILNAKTVCE 242

Query: 227 GDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWI 272
           GDSGGPLVC   +SWLQ G++SWG GC+    PGVY  V+    WI
Sbjct: 243 GDSGGPLVCEFNRSWLQIGIVSWGRGCSNPLYPGVYASVSYFSKWI 288


>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
          Length = 1059

 Score =  204 bits (519), Expect = 7e-53
 Identities = 100/244 (40%), Positives = 145/244 (59%), Gaps = 11/244 (4%)

Query: 30  RMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSLYQVL 89
           RM  R+VGG +   GE+PWQ S++ N  HFCG ++I  +W+++AAHCF    + + +   
Sbjct: 198 RMAGRIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAAHCFNEFQDPTKWVAY 257

Query: 90  LGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPS 149
           +GA  L       + A+V Q+  +PLY    +  DVA++EL +P+PF  +I PVCLP  +
Sbjct: 258 VGATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQPVCLPAAT 317

Query: 150 VIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIK 209
            IF     C ++GWG   +ED L +P +LQK  V ++D   C  LY           ++ 
Sbjct: 318 HIFPPSKKCLISGWGY-LKEDFLVKPEVLQKATVELLDQALCASLYG---------HSLT 367

Query: 210 NDMLCAGFEEGKKDACKGDSGGPLVCLVGQS-WLQAGVISWGEGCARQNRPGVYIRVTAH 268
           + M+CAG+ +GK D+C+GDSGGPLVC      +  AG++SWG GCA   RPGVY RVT  
Sbjct: 368 DRMVCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYARVTRL 427

Query: 269 HNWI 272
            +WI
Sbjct: 428 RDWI 431



 Score =  192 bits (488), Expect = 3e-49
 Identities = 106/277 (38%), Positives = 157/277 (56%), Gaps = 15/277 (5%)

Query: 1   MRRPAAVPLLLLLCFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFC 60
           M+  + VPL  +     Q   A  A  +P    R+VGG     GE PWQVS++    HFC
Sbjct: 473 MQALSTVPLDWVTVPKLQECGARPAMEKP---TRVVGGFGAASGEVPWQVSLKEGSRHFC 529

Query: 61  GGSLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTA 120
           G +++ ++W+L+AAHCF +T +    +  LG   L+  G   +   +R+V  +PLY    
Sbjct: 530 GATVVGDRWLLSAAHCFNHT-KVEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGI 588

Query: 121 SSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQK 180
              D+A++EL +P+ F  YI PVCLP     F  G  C ++GWG+ ++E    +P +LQK
Sbjct: 589 LDFDLAVLELASPLAFNKYIQPVCLPLAIQKFPVGRKCMISGWGN-TQEGNATKPELLQK 647

Query: 181 LAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQS 240
            +V IID   C++LY+          ++ + M+CAGF EGK D+C+GDSGGPL C     
Sbjct: 648 ASVGIIDQKTCSVLYN---------FSLTDRMICAGFLEGKVDSCQGDSGGPLACEEAPG 698

Query: 241 -WLQAGVISWGEGCARQNRPGVYIRVTAHHNWIHRII 276
            +  AG++SWG GCA+  +PGVY R+T    WI  I+
Sbjct: 699 VFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIM 735



 Score =  182 bits (462), Expect = 3e-46
 Identities = 103/250 (41%), Positives = 130/250 (52%), Gaps = 16/250 (6%)

Query: 26   CG-RPRMLNRMVGGQDTQEGEWPWQVSIQ-RNGSHFCGGSLIAEQWVLTAAHCFRNTSET 83
            CG  P  L R+VGG     GEWPWQVS+  R   H CG  L+AE+W+L+AAHCF    + 
Sbjct: 817  CGLAPAALTRIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDP 876

Query: 84   SLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPV 143
              +   LG   L   G      RV ++  +P Y       DVAL+EL  PV  +  + P+
Sbjct: 877  KQWAAFLGTPFL--SGAEGQLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPI 934

Query: 144  CLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGY 203
            CLP+P+     G  C +TGWGS  E   +   R LQK AV ++    C   Y        
Sbjct: 935  CLPEPAPRPPDGTRCVITGWGSVREGGSM--ARQLQKAAVRLLSEQTCRRFY-------- 984

Query: 204  QPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQS-WLQAGVISWGEGCARQNRPGVY 262
             P  I + MLCAGF +G  D+C GD+GGPL C      W+  GV SWG GC R + PGVY
Sbjct: 985  -PVQISSRMLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVY 1043

Query: 263  IRVTAHHNWI 272
             RV A   WI
Sbjct: 1044 TRVAAVRGWI 1053


>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
          Length = 638

 Score =  204 bits (518), Expect = 1e-52
 Identities = 99/242 (40%), Positives = 144/242 (59%), Gaps = 13/242 (5%)

Query: 34  RMVGGQDTQEGEWPWQVSIQRNGS---HFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLL 90
           R+VGG ++  GEWPWQVS+Q   +   H CGGSLI  QWVLTAAHCF       ++++  
Sbjct: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449

Query: 91  GARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPSV 150
           G   L        +++++++  +  Y+ +  + D+AL++L+AP+ +T +  P+CLP    
Sbjct: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509

Query: 151 IFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKN 210
                 NCWVTGWG   E+  +    ILQK+ +P++   +C        +  YQ   I  
Sbjct: 510 TSTIYTNCWVTGWGFSKEKGEIQN--ILQKVNIPLVTNEEC--------QKRYQDYKITQ 559

Query: 211 DMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHN 270
            M+CAG++EG KDACKGDSGGPLVC     W   G+ SWGEGCAR+ +PGVY +V  + +
Sbjct: 560 RMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMD 619

Query: 271 WI 272
           WI
Sbjct: 620 WI 621


>gi|148806900 epidermis-specific serine protease-like protein [Homo
           sapiens]
          Length = 328

 Score =  203 bits (516), Expect = 2e-52
 Identities = 115/277 (41%), Positives = 153/277 (55%), Gaps = 13/277 (4%)

Query: 4   PAAVPLLLLLCFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGS 63
           PA     LLL  G       + CG+P   +R+VGGQD   G WPWQVS+  + +  CGGS
Sbjct: 3   PAGCAFTLLLLLG------ISVCGQPVYSSRVVGGQDAAAGRWPWQVSLHFDHNFICGGS 56

Query: 64  LIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSA 123
           L++E+ +LTAAHC + T  T  Y V LG+  +        Y  V ++  +P YQ T  +A
Sbjct: 57  LVSERLILTAAHCIQPTWTTFSYTVWLGSITVGDSRKRVKY-YVSKIVIHPKYQDT--TA 113

Query: 124 DVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAV 183
           DVAL++L + V FT+ ILP+CLP  +        CWVTGWG   E         LQ+  V
Sbjct: 114 DVALLKLSSQVTFTSAILPICLPSVTKQLAIPPFCWVTGWGKVKESSDRDYHSALQEAEV 173

Query: 184 PIIDTPKCNLLYSKDTEF--GYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSW 241
           PIID   C  LY+    F    +P  IK D +CAG  +  KD+CKGDSGGPL C +   W
Sbjct: 174 PIIDRQACEQLYNPIGIFLPALEP-VIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGVW 232

Query: 242 LQAGVISWGEGCARQNRPGVYIRVTAHHNWIHRIIPK 278
           +Q GV+SWG  C + + PGVY  V  +  WI+  I +
Sbjct: 233 IQTGVVSWGLECGK-SLPGVYTNVIYYQKWINATISR 268


>gi|33695155 hepsin [Homo sapiens]
          Length = 417

 Score =  195 bits (496), Expect = 3e-50
 Identities = 109/263 (41%), Positives = 145/263 (55%), Gaps = 23/263 (8%)

Query: 26  CGRPRM-LNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSET- 83
           CGR ++ ++R+VGG+DT  G WPWQVS++ +G+H CGGSL++  WVLTAAHCF   +   
Sbjct: 153 CGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVL 212

Query: 84  SLYQVLLGARQLVQPGPHAMYARVRQVESNPLY------QGTASSADVALVELEAPVPFT 137
           S ++V  GA  + Q  PH +   V+ V  +  Y          +S D+ALV L +P+P T
Sbjct: 213 SRWRVFAGA--VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLT 270

Query: 138 NYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSK 197
            YI PVCLP        G  C VTGWG+        +  +LQ+  VPII    CN     
Sbjct: 271 EYIQPVCLPAAGQALVDGKICTVTGWGNTQYYG--QQAGVLQEARVPIISNDVCN----- 323

Query: 198 DTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQS----WLQAGVISWGEGC 253
                +    IK  M CAG+ EG  DAC+GDSGGP VC    S    W   G++SWG GC
Sbjct: 324 --GADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGC 381

Query: 254 ARQNRPGVYIRVTAHHNWIHRII 276
           A   +PGVY +V+    WI + I
Sbjct: 382 ALAQKPGVYTKVSDFREWIFQAI 404


>gi|4504481 hepsin [Homo sapiens]
          Length = 417

 Score =  195 bits (496), Expect = 3e-50
 Identities = 109/263 (41%), Positives = 145/263 (55%), Gaps = 23/263 (8%)

Query: 26  CGRPRM-LNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSET- 83
           CGR ++ ++R+VGG+DT  G WPWQVS++ +G+H CGGSL++  WVLTAAHCF   +   
Sbjct: 153 CGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVL 212

Query: 84  SLYQVLLGARQLVQPGPHAMYARVRQVESNPLY------QGTASSADVALVELEAPVPFT 137
           S ++V  GA  + Q  PH +   V+ V  +  Y          +S D+ALV L +P+P T
Sbjct: 213 SRWRVFAGA--VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLT 270

Query: 138 NYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSK 197
            YI PVCLP        G  C VTGWG+        +  +LQ+  VPII    CN     
Sbjct: 271 EYIQPVCLPAAGQALVDGKICTVTGWGNTQYYG--QQAGVLQEARVPIISNDVCN----- 323

Query: 198 DTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQS----WLQAGVISWGEGC 253
                +    IK  M CAG+ EG  DAC+GDSGGP VC    S    W   G++SWG GC
Sbjct: 324 --GADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGC 381

Query: 254 ARQNRPGVYIRVTAHHNWIHRII 276
           A   +PGVY +V+    WI + I
Sbjct: 382 ALAQKPGVYTKVSDFREWIFQAI 404


>gi|21614533 testisin isoform 3 [Homo sapiens]
          Length = 300

 Score =  192 bits (488), Expect = 3e-49
 Identities = 113/287 (39%), Positives = 156/287 (54%), Gaps = 32/287 (11%)

Query: 3   RPAAVPLLLLLCFGSQRAKAATA------CGRPRMLNRMVGGQDTQEGEWPWQVSIQRNG 56
           R A +  LLL   G ++ ++  A      CGR  + +R+VGG+D + G WPWQ S++   
Sbjct: 4   RGALLLALLLARAGLRKPESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLRLWD 63

Query: 57  SHFCGGSLIAEQWVLTAAHCFR---NTSETSLYQVLLGARQLVQP--GPHAMYAR--VRQ 109
           SH CG SL++ +W LTAAHCF    + S+ S + V  G    +       A Y R  V  
Sbjct: 64  SHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSN 123

Query: 110 VESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEE 169
           +  +P Y G  S  D+ALV+L APV +T +I P+CL   +  FE   +CWVTGWG   E+
Sbjct: 124 IYLSPRYLGN-SPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGYIKED 182

Query: 170 DLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDS 229
           + LP P  LQ++ V II+   CN L+ K   + ++ K I  DM              GDS
Sbjct: 183 EALPSPHTLQEVQVAIINNSMCNHLFLK---YSFR-KDIFGDM--------------GDS 224

Query: 230 GGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWIHRII 276
           GGPL C     W Q GV+SWG GC R NRPGVY  ++ H  WI +++
Sbjct: 225 GGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQKLM 271


>gi|4505881 plasminogen [Homo sapiens]
          Length = 810

 Score =  191 bits (485), Expect = 6e-49
 Identities = 101/269 (37%), Positives = 148/269 (55%), Gaps = 22/269 (8%)

Query: 14  CFGSQRAKAATACGRPRML-----NRMVGGQDTQEGEWPWQVSIQ-RNGSHFCGGSLIAE 67
           C   Q A  +  CG+P++       R+VGG       WPWQVS++ R G HFCGG+LI+ 
Sbjct: 555 CDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISP 614

Query: 68  QWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVAL 127
           +WVLTAAHC   +   S Y+V+LGA Q V   PH     V ++   P      +  D+AL
Sbjct: 615 EWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEP------TRKDIAL 668

Query: 128 VELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIID 187
           ++L +P   T+ ++P CLP P+ +      C++TGWG   E        +L++  +P+I+
Sbjct: 669 LKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWG---ETQGTFGAGLLKEAQLPVIE 725

Query: 188 TPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVI 247
              CN        + +    +++  LCAG   G  D+C+GDSGGPLVC     ++  GV 
Sbjct: 726 NKVCN-------RYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVT 778

Query: 248 SWGEGCARQNRPGVYIRVTAHHNWIHRII 276
           SWG GCAR N+PGVY+RV+    WI  ++
Sbjct: 779 SWGLGCARPNKPGVYVRVSRFVTWIEGVM 807


>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
          Length = 318

 Score =  188 bits (478), Expect = 4e-48
 Identities = 100/259 (38%), Positives = 145/259 (55%), Gaps = 14/259 (5%)

Query: 25  ACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETS 84
           ACG   +   + GG ++  G WPWQ S++    H CGGSL++ +WVL+AAHCF+     S
Sbjct: 45  ACGHREIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPS 104

Query: 85  LYQVLLGARQLVQPGPHAMYA-----RVRQVESNPLYQGTASSADVALVELEAPVPFTNY 139
            + V LG     +P P  + A     +V+ +  NP   G   + D+AL+ L + V +  Y
Sbjct: 105 EWTVQLG-ELTSRPTPWNLRAYSSRYKVQDIIVNPDALGVLRN-DIALLRLASSVTYNAY 162

Query: 140 ILPVCLPDPSVIFETGMNCWVTGWG--SPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSK 197
           I P+C+   +  F    +CWVTGWG  SPS   L P P  L++  V I++  +CN L+ +
Sbjct: 163 IQPICIESSTFNFVHRPDCWVTGWGLISPSGTPL-PPPYNLREAQVTILNNTRCNYLFEQ 221

Query: 198 DTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQN 257
            +        I + M CAG E+G  D CKGDSGGPLVC     W Q G++SWG  C + N
Sbjct: 222 PSS----RSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPN 277

Query: 258 RPGVYIRVTAHHNWIHRII 276
           RPGVY  ++ + +WI R++
Sbjct: 278 RPGVYTNISVYFHWIRRVM 296


>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
          Length = 457

 Score =  188 bits (477), Expect = 5e-48
 Identities = 100/252 (39%), Positives = 134/252 (53%), Gaps = 15/252 (5%)

Query: 26  CGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRN--TSET 83
           CG   + +R+VGGQ    G WPWQ S+     H CGGS++A +WV+TAAHC  +   +  
Sbjct: 209 CGARPLASRIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRLARL 268

Query: 84  SLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPV 143
           S ++V  G        PH   A V ++  +PLY       DVAL+ L+  + F++ +  V
Sbjct: 269 SSWRVHAGLVSHSAVRPH-QGALVERIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGAV 327

Query: 144 CLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCN--LLYSKDTEF 201
           CLP     F  G  CWV+GWG            +LQ   VP+  T  CN   +YS     
Sbjct: 328 CLPAKEQHFPKGSRCWVSGWGHTHPSHTYSSD-MLQDTVVPLFSTQLCNSSCVYSG---- 382

Query: 202 GYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGV 261
                 +   MLCAG+ +G+ DAC+GDSGGPLVC  G +W   GV+SWG GCA  N PGV
Sbjct: 383 -----ALTPRMLCAGYLDGRADACQGDSGGPLVCPDGDTWRLVGVVSWGRGCAEPNHPGV 437

Query: 262 YIRVTAHHNWIH 273
           Y +V    +WIH
Sbjct: 438 YAKVAEFLDWIH 449


>gi|4503627 coagulation factor XI precursor [Homo sapiens]
          Length = 625

 Score =  186 bits (473), Expect = 2e-47
 Identities = 96/245 (39%), Positives = 136/245 (55%), Gaps = 19/245 (7%)

Query: 34  RMVGGQDTQEGEWPWQVSIQRNGS---HFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLL 90
           R+VGG  +  GEWPWQV++        H CGGS+I  QW+LTAAHCF       + +V  
Sbjct: 387 RIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYS 446

Query: 91  GARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCLP---D 147
           G     +      +  V+++  +  Y+   S  D+AL++LE  V +T+   P+CLP   D
Sbjct: 447 GILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGD 506

Query: 148 PSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKT 207
            +VI+    +CWVTGWG     D +     LQK  +P++   +C        +  Y+   
Sbjct: 507 RNVIYT---DCWVTGWGYRKLRDKIQNT--LQKAKIPLVTNEEC--------QKRYRGHK 553

Query: 208 IKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTA 267
           I + M+CAG+ EG KDACKGDSGGPL C   + W   G+ SWGEGCA++ RPGVY  V  
Sbjct: 554 ITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVE 613

Query: 268 HHNWI 272
           + +WI
Sbjct: 614 YVDWI 618


>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
          Length = 567

 Score =  183 bits (465), Expect = 1e-46
 Identities = 101/250 (40%), Positives = 135/250 (54%), Gaps = 13/250 (5%)

Query: 26  CGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSL 85
           CG   M  R+VGG    + +WPWQVS+    +H CGG+LI  QWVLTAAHCF  T E  L
Sbjct: 317 CGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVL 376

Query: 86  --YQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPV 143
             ++V  G   L Q  P A  A + ++  N  Y       D+AL+ L  P+  + +I P 
Sbjct: 377 EGWKVYAGTSNLHQL-PEA--ASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPA 433

Query: 144 CLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGY 203
           CLP     F     CW+TG+G   E D    P  L+++ V +ID  KCN       ++  
Sbjct: 434 CLPMHGQTFSLNETCWITGFGKTRETDDKTSP-FLREVQVNLIDFKKCN-------DYLV 485

Query: 204 QPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYI 263
               +   M+CAG   G +D+C+GDSGGPLVC     W  AGV SWG GC ++N+PGVY 
Sbjct: 486 YDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYT 545

Query: 264 RVTAHHNWIH 273
           +VT    WI+
Sbjct: 546 KVTEVLPWIY 555


>gi|40254871 transmembrane protease, serine 11E [Homo sapiens]
          Length = 423

 Score =  182 bits (461), Expect = 4e-46
 Identities = 103/260 (39%), Positives = 144/260 (55%), Gaps = 20/260 (7%)

Query: 14  CFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTA 73
           C G++R+K            R+VGG + +EGEWPWQ S+Q +GSH CG +LI   W+++A
Sbjct: 177 CCGTRRSKTLGQS------LRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSA 230

Query: 74  AHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAP 133
           AHCF      + +    G    V   P  M   +R++  +  Y+  +   D++L EL +P
Sbjct: 231 AHCFTTYKNPARWTASFG----VTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSP 286

Query: 134 VPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNL 193
           VP+TN +  VCLPD S  F+ G   +VTG+G+   +        L++  V +ID   CN 
Sbjct: 287 VPYTNAVHRVCLPDASYEFQPGDVMFVTGFGALKNDGY--SQNHLRQAQVTLIDATTCN- 343

Query: 194 LYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQS-WLQAGVISWGEG 252
                 E       I   MLCAG  EGK DAC+GDSGGPLV    +  W  AG++SWG+ 
Sbjct: 344 ------EPQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDE 397

Query: 253 CARQNRPGVYIRVTAHHNWI 272
           CA+ N+PGVY RVTA  +WI
Sbjct: 398 CAKPNKPGVYTRVTALRDWI 417


>gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]
          Length = 423

 Score =  182 bits (461), Expect = 4e-46
 Identities = 103/260 (39%), Positives = 144/260 (55%), Gaps = 20/260 (7%)

Query: 14  CFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTA 73
           C G++R+K            R+VGG + +EGEWPWQ S+Q +GSH CG +LI   W+++A
Sbjct: 177 CCGTRRSKTLGQS------LRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSA 230

Query: 74  AHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAP 133
           AHCF      + +    G    V   P  M   +R++  +  Y+  +   D++L EL +P
Sbjct: 231 AHCFTTYKNPARWTASFG----VTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSP 286

Query: 134 VPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNL 193
           VP+TN +  VCLPD S  F+ G   +VTG+G+   +        L++  V +ID   CN 
Sbjct: 287 VPYTNAVHRVCLPDASYEFQPGDVMFVTGFGALKNDGY--SQNHLRQAQVTLIDATTCN- 343

Query: 194 LYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQS-WLQAGVISWGEG 252
                 E       I   MLCAG  EGK DAC+GDSGGPLV    +  W  AG++SWG+ 
Sbjct: 344 ------EPQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDE 397

Query: 253 CARQNRPGVYIRVTAHHNWI 272
           CA+ N+PGVY RVTA  +WI
Sbjct: 398 CAKPNKPGVYTRVTALRDWI 417


>gi|222831592 transmembrane protease, serine 7 [Homo sapiens]
          Length = 717

 Score =  181 bits (459), Expect = 7e-46
 Identities = 107/287 (37%), Positives = 143/287 (49%), Gaps = 34/287 (11%)

Query: 13  LCFGSQRAKA-------------ATACGRPRM-LNRMVGGQDTQEGEWPWQVSIQRNGSH 58
           +CF  Q AK                 C R    L+R++GG DT EG WPWQVS+   GS 
Sbjct: 444 ICFRKQNAKCDGTVDCPDGSDEEGCTCSRSSSALHRIIGGTDTLEGGWPWQVSLHFVGSA 503

Query: 59  FCGGSLIAEQWVLTAAHCFRNT--SETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLY 116
           +CG S+I+ +W+L+AAHCF     S+ + +   LG   +   G     + VR++  +  Y
Sbjct: 504 YCGASVISREWLLSAAHCFHGNRLSDPTPWTAHLG---MYVQGNAKFVSPVRRIVVHEYY 560

Query: 117 QGTASSADVALVELEAPVPFT--NYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPE 174
                  D+AL++L    P T    I P+C+P       +G  CWVTGWG   E D    
Sbjct: 561 NSQTFDYDIALLQLSIAWPETLKQLIQPICIPPTGQRVRSGEKCWVTGWGRRHEAD-NKG 619

Query: 175 PRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLV 234
             +LQ+  V +ID   C   Y            I + MLCAG   GK+DACKGDSGGPL 
Sbjct: 620 SLVLQQAEVELIDQTLCVSTYG----------IITSRMLCAGIMSGKRDACKGDSGGPLS 669

Query: 235 C--LVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWIHRIIPKL 279
           C       W+  G++SWG G  R N PGVY RV+    WIH+ +P L
Sbjct: 670 CRRKSDGKWILTGIVSWGHGSGRPNFPGVYTRVSNFVPWIHKYVPSL 716


>gi|11415040 matriptase [Homo sapiens]
          Length = 855

 Score =  181 bits (459), Expect = 7e-46
 Identities = 98/248 (39%), Positives = 140/248 (56%), Gaps = 21/248 (8%)

Query: 34  RMVGGQDTQEGEWPWQVSIQRNGS-HFCGGSLIAEQWVLTAAHCFRNT-----SETSLYQ 87
           R+VGG D  EGEWPWQVS+   G  H CG SLI+  W+++AAHC+ +      S+ + + 
Sbjct: 614 RVVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWT 673

Query: 88  VLLGAR-QLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCLP 146
             LG   Q  +  P     R++++ S+P +       D+AL+ELE P  +++ + P+CLP
Sbjct: 674 AFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLP 733

Query: 147 DPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKC-NLLYSKDTEFGYQP 205
           D S +F  G   WVTGWG            ILQK  + +I+   C NLL          P
Sbjct: 734 DASHVFPAGKAIWVTGWGHTQYGG--TGALILQKGEIRVINQTTCENLL----------P 781

Query: 206 KTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWL-QAGVISWGEGCARQNRPGVYIR 264
           + I   M+C GF  G  D+C+GDSGGPL  +     + QAGV+SWG+GCA++N+PGVY R
Sbjct: 782 QQITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKPGVYTR 841

Query: 265 VTAHHNWI 272
           +    +WI
Sbjct: 842 LPLFRDWI 849


>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
           sapiens]
          Length = 529

 Score =  180 bits (456), Expect = 1e-45
 Identities = 89/242 (36%), Positives = 129/242 (53%), Gaps = 9/242 (3%)

Query: 33  NRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLLGA 92
           +R+VGG+    G WPWQVS+     H CGGS+I  +W++TAAHC         +      
Sbjct: 291 SRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAG 350

Query: 93  RQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPSVIF 152
                   +    +V +V S+P Y     + D+AL++L+ P+ F + + PVCLP+P ++ 
Sbjct: 351 ILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMML 410

Query: 153 ETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDM 212
           +    CW++GWG+  E+    E  +L    V +I+T +CN  Y  D         I   M
Sbjct: 411 QPEQLCWISGWGATEEKGKTSE--VLNAAKVLLIETQRCNSRYVYDN-------LITPAM 461

Query: 213 LCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWI 272
           +CAGF +G  D+C+GDSGGPLV      W   G  SWG GCA+  RPGVY  V    +WI
Sbjct: 462 ICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 521

Query: 273 HR 274
           +R
Sbjct: 522 YR 523


>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
           sapiens]
          Length = 492

 Score =  180 bits (456), Expect = 1e-45
 Identities = 89/242 (36%), Positives = 129/242 (53%), Gaps = 9/242 (3%)

Query: 33  NRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLLGA 92
           +R+VGG+    G WPWQVS+     H CGGS+I  +W++TAAHC         +      
Sbjct: 254 SRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAG 313

Query: 93  RQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPSVIF 152
                   +    +V +V S+P Y     + D+AL++L+ P+ F + + PVCLP+P ++ 
Sbjct: 314 ILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMML 373

Query: 153 ETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDM 212
           +    CW++GWG+  E+    E  +L    V +I+T +CN  Y  D         I   M
Sbjct: 374 QPEQLCWISGWGATEEKGKTSE--VLNAAKVLLIETQRCNSRYVYDN-------LITPAM 424

Query: 213 LCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWI 272
           +CAGF +G  D+C+GDSGGPLV      W   G  SWG GCA+  RPGVY  V    +WI
Sbjct: 425 ICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 484

Query: 273 HR 274
           +R
Sbjct: 485 YR 486


>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
          Length = 416

 Score =  180 bits (456), Expect = 1e-45
 Identities = 103/269 (38%), Positives = 148/269 (55%), Gaps = 20/269 (7%)

Query: 5   AAVPLLLLLCFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSL 64
           AA  +L   C G Q A +          N++V G+ + EG WPWQ S+Q  G H+CG SL
Sbjct: 161 AASEMLTNNCCGRQVANSIITG------NKIVNGKSSLEGAWPWQASMQWKGRHYCGASL 214

Query: 65  IAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSAD 124
           I+ +W+L+AAHCF   + +  + V  G   +V   P+ M  +V+ +  +  Y       D
Sbjct: 215 ISSRWLLSAAHCFAKKNNSKDWTVNFG---IVVNKPY-MTRKVQNIIFHENYSSPGLHDD 270

Query: 125 VALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVP 184
           +ALV+L   V FT YI  +CLP+  +      N  VTGWG+       P   ILQ+  + 
Sbjct: 271 IALVQLAEEVSFTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNGSFPV--ILQEDFLK 328

Query: 185 IIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQS-WLQ 243
           IID   CN  Y+     G+    + + MLCAGF  G+ DAC+ DSGGPL     ++ W  
Sbjct: 329 IIDNKICNASYAYS---GF----VTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHL 381

Query: 244 AGVISWGEGCARQNRPGVYIRVTAHHNWI 272
            G++SWG+GC ++N+PGVY RVT++ NWI
Sbjct: 382 VGIVSWGDGCGKKNKPGVYTRVTSYRNWI 410


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.446 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,003,792
Number of Sequences: 37866
Number of extensions: 652126
Number of successful extensions: 1745
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 172
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1115
Number of HSP's gapped (non-prelim): 192
length of query: 290
length of database: 18,247,518
effective HSP length: 101
effective length of query: 189
effective length of database: 14,423,052
effective search space: 2725956828
effective search space used: 2725956828
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.