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Search of human proteins with 7669477
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo
sapiens]
(741 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo s... 1489 0.0
gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo s... 1431 0.0
gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo s... 1385 0.0
gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo... 1327 0.0
gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens] 702 0.0
gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo sa... 253 6e-67
gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa... 253 6e-67
gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sa... 253 6e-67
gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sa... 253 6e-67
gi|24234756 interleukin enhancer binding factor 3 isoform c [Hom... 170 5e-42
gi|24234753 interleukin enhancer binding factor 3 isoform b [Hom... 170 5e-42
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 170 5e-42
gi|212549555 interleukin enhancer binding factor 3 isoform e [Ho... 169 9e-42
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 169 9e-42
gi|21361745 spermatid perinuclear RNA binding protein [Homo sapi... 166 6e-41
gi|226530771 adenosine deaminase domain containing 1 (testis-spe... 147 3e-35
gi|21245124 adenosine deaminase domain containing 1 (testis-spec... 147 3e-35
gi|226529650 adenosine deaminase domain containing 1 (testis-spe... 132 1e-30
gi|223972690 adenosine deaminase domain containing 2 isoform 2 [... 84 6e-16
gi|223972688 adenosine deaminase domain containing 2 isoform 1 [... 84 6e-16
gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens] 80 5e-15
gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens] 73 1e-12
gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens] 73 1e-12
gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens] 73 1e-12
gi|82659089 staufen isoform a [Homo sapiens] 60 1e-08
gi|82659087 staufen isoform b [Homo sapiens] 60 1e-08
gi|82659085 staufen isoform a [Homo sapiens] 60 1e-08
gi|82659083 staufen isoform a [Homo sapiens] 60 1e-08
gi|82659091 staufen isoform c [Homo sapiens] 56 1e-07
gi|7657625 staufen homolog 2 [Homo sapiens] 53 1e-06
>gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo
sapiens]
Length = 741
Score = 1489 bits (3856), Expect = 0.0
Identities = 741/741 (100%), Positives = 741/741 (100%)
Query: 1 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN 60
MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN
Sbjct: 1 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN 60
Query: 61 GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF 120
GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF
Sbjct: 61 GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF 120
Query: 121 EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF 180
EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF
Sbjct: 121 EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF 180
Query: 181 ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL 240
ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL
Sbjct: 181 ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL 240
Query: 241 NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH 300
NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH
Sbjct: 241 NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH 300
Query: 301 LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG 360
LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG
Sbjct: 301 LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG 360
Query: 361 TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD 420
TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD
Sbjct: 361 TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD 420
Query: 421 QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNH 480
QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNH
Sbjct: 421 QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNH 480
Query: 481 GSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ 540
GSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ
Sbjct: 481 GSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ 540
Query: 541 TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM 600
TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM
Sbjct: 541 TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM 600
Query: 601 YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE 660
YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE
Sbjct: 601 YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE 660
Query: 661 LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFI 720
LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFI
Sbjct: 661 LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFI 720
Query: 721 KAGLGAWVEKPTEQDQFSLTP 741
KAGLGAWVEKPTEQDQFSLTP
Sbjct: 721 KAGLGAWVEKPTEQDQFSLTP 741
>gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo
sapiens]
Length = 714
Score = 1431 bits (3705), Expect = 0.0
Identities = 712/712 (100%), Positives = 712/712 (100%)
Query: 1 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN 60
MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN
Sbjct: 1 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN 60
Query: 61 GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF 120
GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF
Sbjct: 61 GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF 120
Query: 121 EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF 180
EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF
Sbjct: 121 EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF 180
Query: 181 ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL 240
ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL
Sbjct: 181 ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL 240
Query: 241 NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH 300
NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH
Sbjct: 241 NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH 300
Query: 301 LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG 360
LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG
Sbjct: 301 LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG 360
Query: 361 TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD 420
TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD
Sbjct: 361 TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD 420
Query: 421 QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNH 480
QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNH
Sbjct: 421 QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNH 480
Query: 481 GSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ 540
GSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ
Sbjct: 481 GSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ 540
Query: 541 TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM 600
TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM
Sbjct: 541 TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM 600
Query: 601 YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE 660
YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE
Sbjct: 601 YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE 660
Query: 661 LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 712
LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK
Sbjct: 661 LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 712
>gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo
sapiens]
Length = 701
Score = 1385 bits (3585), Expect = 0.0
Identities = 701/741 (94%), Positives = 701/741 (94%), Gaps = 40/741 (5%)
Query: 1 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN 60
MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN
Sbjct: 1 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN 60
Query: 61 GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF 120
GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF
Sbjct: 61 GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF 120
Query: 121 EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF 180
EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF
Sbjct: 121 EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF 180
Query: 181 ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL 240
ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL
Sbjct: 181 ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL 240
Query: 241 NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH 300
NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH
Sbjct: 241 NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH 300
Query: 301 LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG 360
LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG
Sbjct: 301 LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG 360
Query: 361 TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD 420
TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD
Sbjct: 361 TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD 420
Query: 421 QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNH 480
QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILE
Sbjct: 421 QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILE--------------- 465
Query: 481 GSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ 540
EPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ
Sbjct: 466 -------------------------EPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ 500
Query: 541 TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM 600
TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM
Sbjct: 501 TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM 560
Query: 601 YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE 660
YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE
Sbjct: 561 YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE 620
Query: 661 LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFI 720
LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFI
Sbjct: 621 LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFI 680
Query: 721 KAGLGAWVEKPTEQDQFSLTP 741
KAGLGAWVEKPTEQDQFSLTP
Sbjct: 681 KAGLGAWVEKPTEQDQFSLTP 701
>gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo
sapiens]
Length = 674
Score = 1327 bits (3434), Expect = 0.0
Identities = 672/712 (94%), Positives = 672/712 (94%), Gaps = 40/712 (5%)
Query: 1 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN 60
MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN
Sbjct: 1 MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSN 60
Query: 61 GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF 120
GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF
Sbjct: 61 GHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVF 120
Query: 121 EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF 180
EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF
Sbjct: 121 EGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGF 180
Query: 181 ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL 240
ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL
Sbjct: 181 ETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMIL 240
Query: 241 NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH 300
NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH
Sbjct: 241 NELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLH 300
Query: 301 LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG 360
LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG
Sbjct: 301 LDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG 360
Query: 361 TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD 420
TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD
Sbjct: 361 TDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDD 420
Query: 421 QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNH 480
QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILE
Sbjct: 421 QKRSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILE--------------- 465
Query: 481 GSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ 540
EPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ
Sbjct: 466 -------------------------EPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQ 500
Query: 541 TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM 600
TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM
Sbjct: 501 TWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAM 560
Query: 601 YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE 660
YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE
Sbjct: 561 YQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDE 620
Query: 661 LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 712
LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK
Sbjct: 621 LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 672
>gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]
Length = 739
Score = 702 bits (1813), Expect = 0.0
Identities = 376/738 (50%), Positives = 492/738 (66%), Gaps = 57/738 (7%)
Query: 4 EDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLEEGSNGHS 63
ED++ +S+SS +VKENRN+ N++ + P + GG G RKRPLEEG+ GH
Sbjct: 57 EDDDTLSTSSAEVKENRNVGNLAAR------PPPSGDRARGGAPGAKRKRPLEEGNGGHL 110
Query: 64 KYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEGS 123
+K V PKNAL+QL+E++PGLQY +SQTGPVHAP+F ++VEVNG FEG+
Sbjct: 111 CKLQLVWKKLSWSVAPKNALVQLHELRPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFEGT 170
Query: 124 GPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETP 183
GPTKKKAK+ AAE ALRSFVQFPNA +AHLAMG TDFTSDQADFPDTLF FE P
Sbjct: 171 GPTKKKAKMRAAELALRSFVQFPNACQAHLAMGGGPGPGTDFTSDQADFPDTLFQEFEPP 230
Query: 184 DKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPPFPPPSGKNPVMILNEL 243
A P G D+ S A P P P P +NPV++LN L
Sbjct: 231 --APRPGLAGGRPGDAALLSAAYGRRRLLCRALDLVGPTPATP--AAPGERNPVVLLNRL 286
Query: 244 RPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQ 303
R GL+Y L+E E A+SFVM+V VDG+ FEGSGR+KKLA+ +AAQ+AL +F++ Q
Sbjct: 287 RAGLRYVCLAEPAERRARSFVMAVSVDGRTFEGSGRSKKLARGQAAQAALQELFDI---Q 343
Query: 304 TPSRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDV 363
P P + +PQ AD++S+LV KF ++T + + HAR K LAG+VMT G D
Sbjct: 344 MPGH--APGRARRTPMPQEFADSISQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDA 401
Query: 364 KDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLN-NKDDQK 422
+ A+V+++S+GTKCI+GE++SD+GL +NDCHAE+++RR+ L FLYTQLEL+L+ ++D +
Sbjct: 402 RQAQVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSE 461
Query: 423 RSIFQKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGS 482
RSIF + + GG+RL+EN+ FHLY+STSPCGDAR+ SP+E
Sbjct: 462 RSIFVRLKEGGYRLRENILFHLYVSTSPCGDARLHSPYE--------------------- 500
Query: 483 LQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTW 542
+ +D +S +H RK RG LRTKIESGEGT+PVR +++QTW
Sbjct: 501 -------ITTDLHSS------------KHLVRKFRGHLRTKIESGEGTVPVRGPSAVQTW 541
Query: 543 DGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQ 602
DGVL GE+L+TMSC+DKIARWNV+G+QG+LLS FVEP+Y SI++GSL+H HL+R M
Sbjct: 542 DGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEPVYLQSIVVGSLHHTGHLARVMSH 601
Query: 603 RISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDELG 662
R+ + LP Y N+PLLSG+S+AEARQPGK+P FS+NW VG + +E+INATTG+ G
Sbjct: 602 RMEGVGQLPASYRHNRPLLSGVSDAEARQPGKSPPFSMNWVVGSADLEIINATTGRRSCG 661
Query: 663 RASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKA 722
SRLCKH L RW R++G++ S S P++Y E+KL A YQ+ K +LF AF KA
Sbjct: 662 GPSRLCKHVLSARWARLYGRL-STRTPSPGDTPSMYCEAKLGAHTYQSVKQQLFKAFQKA 720
Query: 723 GLGAWVEKPTEQDQFSLT 740
GLG WV KP EQ QF LT
Sbjct: 721 GLGTWVRKPPEQQQFLLT 738
>gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo
sapiens]
Length = 931
Score = 253 bits (645), Expect = 6e-67
Identities = 179/535 (33%), Positives = 269/535 (50%), Gaps = 93/535 (17%)
Query: 248 KYDFLSESGESHAKSFVMSVVVDGQFFEG-SGRNKKLAKARAAQSALAAIFN-------- 298
++ + +SG H FV V G++F +KK K AA +AL +
Sbjct: 448 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 507
Query: 299 -----------------LHLDQTPSRQP--IPSEGLQLHLPQVLADAVSRLVLGKFGDLT 339
L L ++P QP +P G H D ++ L F LT
Sbjct: 508 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFH------DQIAMLSHRCFNTLT 561
Query: 340 DNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIIS 399
++F RK+LA ++M ++ V+S+ TG +C+ G+ +S +G +NDCHAEIIS
Sbjct: 562 NSFQPSLLGRKILAAIIMKKDSEDMGV-VVSLGTGNRCVKGDSLSLKGETVNDCHAEIIS 620
Query: 400 RRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGG-FRLKENVQFHLYISTSPCGDARIFS 458
RR +RFLY++L Y N K SIF+ ++ G ++K+ V FHLYIST+PCGD +F
Sbjct: 621 RRGFIRFLYSELMKY--NSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFD 678
Query: 459 PHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARG 518
+S + ++ S + R + +P +G
Sbjct: 679 ---------KSCSDRAME-----STESRHYPVFENPK---------------------QG 703
Query: 519 QLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVE 578
+LRTK+E+GEGTIPV S+ + TWDG+ GERL TMSCSDKI RWNV+G+QG+LL+ F++
Sbjct: 704 KLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQ 763
Query: 579 PIYFSSIILGSLYHGDHLSRAMYQRI----SNIED-LPPLYTLNKPLLSGISNAEA-RQP 632
PIY S+ LG L+ HL+RA+ R+ S ED L + +N P + +S ++ RQ
Sbjct: 764 PIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQS 823
Query: 633 GKAPNFSVNWTVGDS-AIEVINATTG-----KDELGRASRLCKHALYCRWMRVHGKVPSH 686
GK SVNW + D +E+++ T G ++EL R S+ L+ K+ S
Sbjct: 824 GKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLF-------KKLCSF 876
Query: 687 LLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP 741
R + + + Y E+K AA++Y+ AK G G W+ KP E+ F L P
Sbjct: 877 RYRRDLLRLS-YGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYLCP 930
Score = 47.4 bits (111), Expect = 5e-05
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 54/209 (25%)
Query: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVF-EGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 152
++ ++ Q+GP H P F V +NG+ F +KK AK AA KA+ ++ A ++
Sbjct: 225 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDS- 283
Query: 153 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 212
K+E S S
Sbjct: 284 -------------------------------GKSE--------------ESSHYSTEKES 298
Query: 213 VPASLAQPPLPVLPPFPPPSGKNPVMIL----NELRPGLKYDFLSESGESHAKSFVMSVV 268
+ +Q P P F SGK+PV L ++L ++ LS+ G +H F V
Sbjct: 299 EKTAESQTPTPSATSF--FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVA 356
Query: 269 VDGQFFEG-SGRNKKLAKARAAQSALAAI 296
V Q F S +KK+AK AA+ A+ A+
Sbjct: 357 VGAQTFPSVSAPSKKVAKQMAAEEAMKAL 385
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 79 PKNALMQ-LNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAE 136
P L++ ++++ ++ LLS+ GP H P F V V Q F S P+KK AK AAE
Sbjct: 320 PVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAE 379
Query: 137 KALRS 141
+A+++
Sbjct: 380 EAMKA 384
Score = 37.0 bits (84), Expect = 0.066
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAEKALRSFV 143
++ L+ Q+GP H P FV +V G+ F +KK+ K AA+ ALR +
Sbjct: 448 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 498
Score = 30.4 bits (67), Expect = 6.2
Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 5/68 (7%)
Query: 234 KNPVMILNELRP----GLKYDFLSESGESHAKSFVMSVVVDG-QFFEGSGRNKKLAKARA 288
KNP+ L E +++ + +SG H F VV++G +F +KK+AK A
Sbjct: 207 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 266
Query: 289 AQSALAAI 296
A A+ +
Sbjct: 267 AMKAMTIL 274
>gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
sapiens]
Length = 1181
Score = 253 bits (645), Expect = 6e-67
Identities = 174/509 (34%), Positives = 264/509 (51%), Gaps = 67/509 (13%)
Query: 248 KYDFLSESGESHAKSFVMSVVVDGQFFEG-SGRNKKLAKARAAQSALAAIFNLHLD-QTP 305
++ + +SG H FV V G++F +KK K AA +AL + + +
Sbjct: 724 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 783
Query: 306 SRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKD 365
+P G H D ++ L F LT++F RK+LA ++M ++
Sbjct: 784 GFTELPLTGSTFH------DQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMG 837
Query: 366 AKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSI 425
V+S+ TG +C+ G+ +S +G +NDCHAEIISRR +RFLY++L Y N K SI
Sbjct: 838 V-VVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKY--NSQTAKDSI 894
Query: 426 FQKSERGG-FRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQ 484
F+ ++ G ++K+ V FHLYIST+PCGD +F +S + ++ S +
Sbjct: 895 FEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFD---------KSCSDRAME-----STE 940
Query: 485 PRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDG 544
R + +P +G+LRTK+E+GEGTIPV S+ + TWDG
Sbjct: 941 SRHYPVFENPK---------------------QGKLRTKVENGEGTIPVESSDIVPTWDG 979
Query: 545 VLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRI 604
+ GERL TMSCSDKI RWNV+G+QG+LL+ F++PIY S+ LG L+ HL+RA+ R+
Sbjct: 980 IRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRV 1039
Query: 605 ----SNIED-LPPLYTLNKPLLSGISNAEA-RQPGKAPNFSVNWTVGDS-AIEVINATTG 657
S ED L + +N P + +S ++ RQ GK SVNW + D +E+++ T G
Sbjct: 1040 TRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRG 1099
Query: 658 -----KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 712
++EL R S+ L+ K+ S R + + + Y E+K AA++Y+ AK
Sbjct: 1100 TVDGPRNELSRVSKKNIFLLF-------KKLCSFRYRRDLLRLS-YGEAKKAARDYETAK 1151
Query: 713 ARLFTAFIKAGLGAWVEKPTEQDQFSLTP 741
G G W+ KP E+ F L P
Sbjct: 1152 NYFKKGLKDMGYGNWISKPQEEKNFYLCP 1180
Score = 47.4 bits (111), Expect = 5e-05
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 54/209 (25%)
Query: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVF-EGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 152
++ ++ Q+GP H P F V +NG+ F +KK AK AA KA+ ++ A ++
Sbjct: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDS- 578
Query: 153 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 212
K+E S S
Sbjct: 579 -------------------------------GKSE--------------ESSHYSTEKES 593
Query: 213 VPASLAQPPLPVLPPFPPPSGKNPVMIL----NELRPGLKYDFLSESGESHAKSFVMSVV 268
+ +Q P P F SGK+PV L ++L ++ LS+ G +H F V
Sbjct: 594 EKTAESQTPTPSATSF--FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVA 651
Query: 269 VDGQFFEG-SGRNKKLAKARAAQSALAAI 296
V Q F S +KK+AK AA+ A+ A+
Sbjct: 652 VGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 79 PKNALMQ-LNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAE 136
P L++ ++++ ++ LLS+ GP H P F V V Q F S P+KK AK AAE
Sbjct: 615 PVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAE 674
Query: 137 KALRS 141
+A+++
Sbjct: 675 EAMKA 679
Score = 37.0 bits (84), Expect = 0.066
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAEKALRSFV 143
++ L+ Q+GP H P FV +V G+ F +KK+ K AA+ ALR +
Sbjct: 724 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 774
Score = 30.4 bits (67), Expect = 6.2
Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 5/68 (7%)
Query: 234 KNPVMILNELRP----GLKYDFLSESGESHAKSFVMSVVVDG-QFFEGSGRNKKLAKARA 288
KNP+ L E +++ + +SG H F VV++G +F +KK+AK A
Sbjct: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
Query: 289 AQSALAAI 296
A A+ +
Sbjct: 562 AMKAMTIL 569
>gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo
sapiens]
Length = 1200
Score = 253 bits (645), Expect = 6e-67
Identities = 174/509 (34%), Positives = 264/509 (51%), Gaps = 67/509 (13%)
Query: 248 KYDFLSESGESHAKSFVMSVVVDGQFFEG-SGRNKKLAKARAAQSALAAIFNLHLD-QTP 305
++ + +SG H FV V G++F +KK K AA +AL + + +
Sbjct: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 802
Query: 306 SRQPIPSEGLQLHLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKD 365
+P G H D ++ L F LT++F RK+LA ++M ++
Sbjct: 803 GFTELPLTGSTFH------DQIAMLSHRCFNTLTNSFQPSLLGRKILAAIIMKKDSEDMG 856
Query: 366 AKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSI 425
V+S+ TG +C+ G+ +S +G +NDCHAEIISRR +RFLY++L Y N K SI
Sbjct: 857 V-VVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSELMKY--NSQTAKDSI 913
Query: 426 FQKSERGG-FRLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQ 484
F+ ++ G ++K+ V FHLYIST+PCGD +F +S + ++ S +
Sbjct: 914 FEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFD---------KSCSDRAME-----STE 959
Query: 485 PRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDG 544
R + +P +G+LRTK+E+GEGTIPV S+ + TWDG
Sbjct: 960 SRHYPVFENPK---------------------QGKLRTKVENGEGTIPVESSDIVPTWDG 998
Query: 545 VLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRI 604
+ GERL TMSCSDKI RWNV+G+QG+LL+ F++PIY S+ LG L+ HL+RA+ R+
Sbjct: 999 IRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHLTRAICCRV 1058
Query: 605 ----SNIED-LPPLYTLNKPLLSGISNAEA-RQPGKAPNFSVNWTVGDS-AIEVINATTG 657
S ED L + +N P + +S ++ RQ GK SVNW + D +E+++ T G
Sbjct: 1059 TRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRG 1118
Query: 658 -----KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 712
++EL R S+ L+ K+ S R + + + Y E+K AA++Y+ AK
Sbjct: 1119 TVDGPRNELSRVSKKNIFLLF-------KKLCSFRYRRDLLRLS-YGEAKKAARDYETAK 1170
Query: 713 ARLFTAFIKAGLGAWVEKPTEQDQFSLTP 741
G G W+ KP E+ F L P
Sbjct: 1171 NYFKKGLKDMGYGNWISKPQEEKNFYLCP 1199
Score = 47.4 bits (111), Expect = 5e-05
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 54/209 (25%)
Query: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVF-EGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 152
++ ++ Q+GP H P F V +NG+ F +KK AK AA KA+ ++ A ++
Sbjct: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDS- 578
Query: 153 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 212
K+E S S
Sbjct: 579 -------------------------------GKSE--------------ESSHYSTEKES 593
Query: 213 VPASLAQPPLPVLPPFPPPSGKNPVMIL----NELRPGLKYDFLSESGESHAKSFVMSVV 268
+ +Q P P F SGK+PV L ++L ++ LS+ G +H F V
Sbjct: 594 EKTAESQTPTPSATSF--FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVA 651
Query: 269 VDGQFFEG-SGRNKKLAKARAAQSALAAI 296
V Q F S +KK+AK AA+ A+ A+
Sbjct: 652 VGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 79 PKNALMQ-LNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAE 136
P L++ ++++ ++ LLS+ GP H P F V V Q F S P+KK AK AAE
Sbjct: 615 PVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAE 674
Query: 137 KALRS 141
+A+++
Sbjct: 675 EAMKA 679
Score = 37.0 bits (84), Expect = 0.066
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAEKALRSFV 143
++ L+ Q+GP H P FV +V G+ F +KK+ K AA+ ALR +
Sbjct: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 793
Score = 30.4 bits (67), Expect = 6.2
Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 5/68 (7%)
Query: 234 KNPVMILNELRP----GLKYDFLSESGESHAKSFVMSVVVDG-QFFEGSGRNKKLAKARA 288
KNP+ L E +++ + +SG H F VV++G +F +KK+AK A
Sbjct: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
Query: 289 AQSALAAI 296
A A+ +
Sbjct: 562 AMKAMTIL 569
>gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo
sapiens]
Length = 1226
Score = 253 bits (645), Expect = 6e-67
Identities = 179/535 (33%), Positives = 269/535 (50%), Gaps = 93/535 (17%)
Query: 248 KYDFLSESGESHAKSFVMSVVVDGQFFEG-SGRNKKLAKARAAQSALAAIFN-------- 298
++ + +SG H FV V G++F +KK K AA +AL +
Sbjct: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 802
Query: 299 -----------------LHLDQTPSRQP--IPSEGLQLHLPQVLADAVSRLVLGKFGDLT 339
L L ++P QP +P G H D ++ L F LT
Sbjct: 803 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFH------DQIAMLSHRCFNTLT 856
Query: 340 DNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIIS 399
++F RK+LA ++M ++ V+S+ TG +C+ G+ +S +G +NDCHAEIIS
Sbjct: 857 NSFQPSLLGRKILAAIIMKKDSEDMGV-VVSLGTGNRCVKGDSLSLKGETVNDCHAEIIS 915
Query: 400 RRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGG-FRLKENVQFHLYISTSPCGDARIFS 458
RR +RFLY++L Y N K SIF+ ++ G ++K+ V FHLYIST+PCGD +F
Sbjct: 916 RRGFIRFLYSELMKY--NSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFD 973
Query: 459 PHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLLSDPSTSTFQGAGTTEPADRHPNRKARG 518
+S + ++ S + R + +P +G
Sbjct: 974 ---------KSCSDRAME-----STESRHYPVFENPK---------------------QG 998
Query: 519 QLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVE 578
+LRTK+E+GEGTIPV S+ + TWDG+ GERL TMSCSDKI RWNV+G+QG+LL+ F++
Sbjct: 999 KLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQ 1058
Query: 579 PIYFSSIILGSLYHGDHLSRAMYQRI----SNIED-LPPLYTLNKPLLSGISNAEA-RQP 632
PIY S+ LG L+ HL+RA+ R+ S ED L + +N P + +S ++ RQ
Sbjct: 1059 PIYLKSVTLGYLFSQGHLTRAICCRVTRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQS 1118
Query: 633 GKAPNFSVNWTVGDS-AIEVINATTG-----KDELGRASRLCKHALYCRWMRVHGKVPSH 686
GK SVNW + D +E+++ T G ++EL R S+ L+ K+ S
Sbjct: 1119 GKTKETSVNWCLADGYDLEILDGTRGTVDGPRNELSRVSKKNIFLLF-------KKLCSF 1171
Query: 687 LLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSLTP 741
R + + + Y E+K AA++Y+ AK G G W+ KP E+ F L P
Sbjct: 1172 RYRRDLLRLS-YGEAKKAARDYETAKNYFKKGLKDMGYGNWISKPQEEKNFYLCP 1225
Score = 47.4 bits (111), Expect = 5e-05
Identities = 52/209 (24%), Positives = 80/209 (38%), Gaps = 54/209 (25%)
Query: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVF-EGSGPTKKKAKLHAAEKALRSFVQFPNASEAH 152
++ ++ Q+GP H P F V +NG+ F +KK AK AA KA+ ++ A ++
Sbjct: 520 EFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDS- 578
Query: 153 LAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASP 212
K+E S S
Sbjct: 579 -------------------------------GKSE--------------ESSHYSTEKES 593
Query: 213 VPASLAQPPLPVLPPFPPPSGKNPVMIL----NELRPGLKYDFLSESGESHAKSFVMSVV 268
+ +Q P P F SGK+PV L ++L ++ LS+ G +H F V
Sbjct: 594 EKTAESQTPTPSATSF--FSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVA 651
Query: 269 VDGQFFEG-SGRNKKLAKARAAQSALAAI 296
V Q F S +KK+AK AA+ A+ A+
Sbjct: 652 VGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 2/65 (3%)
Query: 79 PKNALMQ-LNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAE 136
P L++ ++++ ++ LLS+ GP H P F V V Q F S P+KK AK AAE
Sbjct: 615 PVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAE 674
Query: 137 KALRS 141
+A+++
Sbjct: 675 EAMKA 679
Score = 37.0 bits (84), Expect = 0.066
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEG-SGPTKKKAKLHAAEKALRSFV 143
++ L+ Q+GP H P FV +V G+ F +KK+ K AA+ ALR +
Sbjct: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLI 793
Score = 30.4 bits (67), Expect = 6.2
Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 5/68 (7%)
Query: 234 KNPVMILNELRP----GLKYDFLSESGESHAKSFVMSVVVDG-QFFEGSGRNKKLAKARA 288
KNP+ L E +++ + +SG H F VV++G +F +KK+AK A
Sbjct: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
Query: 289 AQSALAAI 296
A A+ +
Sbjct: 562 AMKAMTIL 569
>gi|24234756 interleukin enhancer binding factor 3 isoform c [Homo
sapiens]
Length = 690
Score = 170 bits (430), Expect = 5e-42
Identities = 115/271 (42%), Positives = 150/271 (55%), Gaps = 39/271 (14%)
Query: 52 KRPLEEGSNGHS----KYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAP 107
KRP+EE S K +++K+ + P NALM+LN++KPGLQY L+SQTGPVHAP
Sbjct: 371 KRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAP 430
Query: 108 LFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTS 167
+F MSVEV+G FE SGP+KK AKLH A K L+ + P +E GR S D
Sbjct: 431 IFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQD-MGLPTGAE-----GRDSSKGEDSAE 484
Query: 168 DQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPP 227
+ +A+P + ++ S+ +A P A+ Q P+
Sbjct: 485 E---------------TEAKPAVVAPAPVVEAVSTPS----AAFPSDATAEQGPILT--- 522
Query: 228 FPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKAR 287
GKNPVM LNE R GLKY+ +SE+G SH K FVM V VDGQ F+G+G NKK+AKA
Sbjct: 523 ---KHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAY 579
Query: 288 AAQSALAAIF---NLHLD-QTPSRQPIPSEG 314
AA +AL +F L LD R P+P G
Sbjct: 580 AALAALEKLFPDTPLALDANKKKRAPVPVRG 610
>gi|24234753 interleukin enhancer binding factor 3 isoform b [Homo
sapiens]
Length = 702
Score = 170 bits (430), Expect = 5e-42
Identities = 115/271 (42%), Positives = 150/271 (55%), Gaps = 39/271 (14%)
Query: 52 KRPLEEGSNGHS----KYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAP 107
KRP+EE S K +++K+ + P NALM+LN++KPGLQY L+SQTGPVHAP
Sbjct: 371 KRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAP 430
Query: 108 LFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTS 167
+F MSVEV+G FE SGP+KK AKLH A K L+ + P +E GR S D
Sbjct: 431 IFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQD-MGLPTGAE-----GRDSSKGEDSAE 484
Query: 168 DQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPP 227
+ +A+P + ++ S+ +A P A+ Q P+
Sbjct: 485 E---------------TEAKPAVVAPAPVVEAVSTPS----AAFPSDATAEQGPILT--- 522
Query: 228 FPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKAR 287
GKNPVM LNE R GLKY+ +SE+G SH K FVM V VDGQ F+G+G NKK+AKA
Sbjct: 523 ---KHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAY 579
Query: 288 AAQSALAAIF---NLHLD-QTPSRQPIPSEG 314
AA +AL +F L LD R P+P G
Sbjct: 580 AALAALEKLFPDTPLALDANKKKRAPVPVRG 610
>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
sapiens]
Length = 894
Score = 170 bits (430), Expect = 5e-42
Identities = 115/271 (42%), Positives = 150/271 (55%), Gaps = 39/271 (14%)
Query: 52 KRPLEEGSNGHS----KYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAP 107
KRP+EE S K +++K+ + P NALM+LN++KPGLQY L+SQTGPVHAP
Sbjct: 371 KRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAP 430
Query: 108 LFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTS 167
+F MSVEV+G FE SGP+KK AKLH A K L+ + P +E GR S D
Sbjct: 431 IFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQD-MGLPTGAE-----GRDSSKGEDSAE 484
Query: 168 DQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPP 227
+ +A+P + ++ S+ +A P A+ Q P+
Sbjct: 485 E---------------TEAKPAVVAPAPVVEAVSTPS----AAFPSDATAEQGPILT--- 522
Query: 228 FPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKAR 287
GKNPVM LNE R GLKY+ +SE+G SH K FVM V VDGQ F+G+G NKK+AKA
Sbjct: 523 ---KHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAY 579
Query: 288 AAQSALAAIF---NLHLD-QTPSRQPIPSEG 314
AA +AL +F L LD R P+P G
Sbjct: 580 AALAALEKLFPDTPLALDANKKKRAPVPVRG 610
>gi|212549555 interleukin enhancer binding factor 3 isoform e [Homo
sapiens]
Length = 706
Score = 169 bits (428), Expect = 9e-42
Identities = 113/271 (41%), Positives = 142/271 (52%), Gaps = 35/271 (12%)
Query: 52 KRPLEEGSNGHS----KYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAP 107
KRP+EE S K +++K+ + P NALM+LN++KPGLQY L+SQTGPVHAP
Sbjct: 371 KRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAP 430
Query: 108 LFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTS 167
+F MSVEV+G FE SGP+KK AKLH A K L+ + P +E + S
Sbjct: 431 IFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQD-MGLPTGAEGRDSSKGEDSAEETEAK 489
Query: 168 DQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPP 227
P + TP A P S A + P+L
Sbjct: 490 PAVVAPAPVVEAVSTPSAAFP----------------------SDATAENVKQQGPIL-- 525
Query: 228 FPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKAR 287
GKNPVM LNE R GLKY+ +SE+G SH K FVM V VDGQ F+G+G NKK+AKA
Sbjct: 526 --TKHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAY 583
Query: 288 AAQSALAAIF---NLHLD-QTPSRQPIPSEG 314
AA +AL +F L LD R P+P G
Sbjct: 584 AALAALEKLFPDTPLALDANKKKRAPVPVRG 614
>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
sapiens]
Length = 898
Score = 169 bits (428), Expect = 9e-42
Identities = 113/271 (41%), Positives = 142/271 (52%), Gaps = 35/271 (12%)
Query: 52 KRPLEEGSNGHS----KYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTGPVHAP 107
KRP+EE S K +++K+ + P NALM+LN++KPGLQY L+SQTGPVHAP
Sbjct: 371 KRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAP 430
Query: 108 LFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTS 167
+F MSVEV+G FE SGP+KK AKLH A K L+ + P +E + S
Sbjct: 431 IFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQD-MGLPTGAEGRDSSKGEDSAEETEAK 489
Query: 168 DQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLAQPPLPVLPP 227
P + TP A P S A + P+L
Sbjct: 490 PAVVAPAPVVEAVSTPSAAFP----------------------SDATAENVKQQGPIL-- 525
Query: 228 FPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKAR 287
GKNPVM LNE R GLKY+ +SE+G SH K FVM V VDGQ F+G+G NKK+AKA
Sbjct: 526 --TKHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAY 583
Query: 288 AAQSALAAIF---NLHLD-QTPSRQPIPSEG 314
AA +AL +F L LD R P+P G
Sbjct: 584 AALAALEKLFPDTPLALDANKKKRAPVPVRG 614
>gi|21361745 spermatid perinuclear RNA binding protein [Homo
sapiens]
Length = 672
Score = 166 bits (421), Expect = 6e-41
Identities = 111/260 (42%), Positives = 141/260 (54%), Gaps = 38/260 (14%)
Query: 45 GGGGPGRKRPLEEGSNGHSKYRLKKRRKTPGPVLPK------NALMQLNEIKPGLQYTLL 98
G G KRP E+G G K KK ++ +L NALM+LN+I+PGLQY LL
Sbjct: 349 GAGSSALKRPFEDGL-GDDKDPNKKMKRNLRKILDSKAIDLMNALMRLNQIRPGLQYKLL 407
Query: 99 SQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRT 158
SQ+GPVHAP+F MSV+V+G +E SGP+KK AKLH A K L+ AMG
Sbjct: 408 SQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQ-------------AMGYP 454
Query: 159 LSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLA 218
+ D +D E D V SN S +++G+ + S
Sbjct: 455 TGFDADIECMSSD---------EKSDNESKNETVSSN---SSNNTGNSTTETSSTLEVRT 502
Query: 219 QPPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSG 278
Q P+ SGKNPVM LNE R GLKY+ +SE+G SH K FVM V VDGQ F G+G
Sbjct: 503 QGPILT------ASGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAG 556
Query: 279 RNKKLAKARAAQSALAAIFN 298
NKK+AKA AA +AL +F+
Sbjct: 557 PNKKVAKASAALAALEKLFS 576
Score = 75.9 bits (185), Expect = 1e-13
Identities = 41/81 (50%), Positives = 52/81 (64%), Gaps = 3/81 (3%)
Query: 72 KTPGPVLP---KNALMQLNEIKPGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKK 128
+T GP+L KN +M+LNE + GL+Y L+S+TG H FVM VEV+GQ F G+GP KK
Sbjct: 501 RTQGPILTASGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKK 560
Query: 129 KAKLHAAEKALRSFVQFPNAS 149
AK AA AL PNA+
Sbjct: 561 VAKASAALAALEKLFSGPNAA 581
>gi|226530771 adenosine deaminase domain containing 1
(testis-specific) isoform 3 [Homo sapiens]
Length = 558
Score = 147 bits (371), Expect = 3e-35
Identities = 155/562 (27%), Positives = 243/562 (43%), Gaps = 105/562 (18%)
Query: 223 PVLPPFPPPS--------GK-NPVMILNEL----RPGLKYDFLSESGESHAKSFVMSVVV 269
PVLPP P G+ NPV L++ R L +G F VV
Sbjct: 57 PVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVV 116
Query: 270 DG-QFFEGSGRNKKLAKARAAQSALAAIFNL-----HLDQTPSRQPIPSEGLQL----HL 319
DG Q+ G G+NKK +++ AA+ AL + L + +T P P+E + L ++
Sbjct: 117 DGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYV 176
Query: 320 PQVLADA-------VSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVS 372
+V + +S++V +F L N S LA ++ +V+++
Sbjct: 177 SKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQ---HEVVAIG 233
Query: 373 TGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLEL-YLNNKDDQKRSIFQKSER 431
TG + + D G L+D HA + +RRSLLR+ Y QL L Y N ++SIF
Sbjct: 234 TGEYNYSQDIKPD-GRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPT 292
Query: 432 GGF-RLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGL 490
LK+N+ LY++ P GS Q +
Sbjct: 293 SNLLTLKQNINICLYMNQLP-----------------------------KGSAQIKSQLR 323
Query: 491 LSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGER 550
L+ S S F+ E H + + L DGV R
Sbjct: 324 LNPHSISAFEA---NEELCLHVAVEGKIYLTVYCPK----------------DGV---NR 361
Query: 551 LLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGD--HLSRAMYQRISN-- 606
+ +MS SDK+ RW V+G+QG+LLS F++P+Y SSI++G D L A+ QR+ +
Sbjct: 362 ISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDAL 421
Query: 607 IEDLPPLYTLNKPLLSGISNAEARQPGKAPNF-SVNWTVGDSAIEVINATTG-------- 657
LP Y +N+P +S + +A Q F S+NW GD ++E+++ +G
Sbjct: 422 TSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSPF 481
Query: 658 KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFT 717
K + ASRLCK A+ R+ + + LL + YH +K + YQ AK +L +
Sbjct: 482 KSGMSMASRLCKAAMLSRFNLLAKEAKKELLEA-----GTYHAAKCMSASYQEAKCKLKS 536
Query: 718 AFIKAGLGAWVEKPTEQDQFSL 739
+ G G+W+ K +QF++
Sbjct: 537 YLQQHGYGSWIVKSPCIEQFNM 558
>gi|21245124 adenosine deaminase domain containing 1
(testis-specific) isoform 1 [Homo sapiens]
Length = 576
Score = 147 bits (371), Expect = 3e-35
Identities = 155/562 (27%), Positives = 243/562 (43%), Gaps = 105/562 (18%)
Query: 223 PVLPPFPPPS--------GK-NPVMILNEL----RPGLKYDFLSESGESHAKSFVMSVVV 269
PVLPP P G+ NPV L++ R L +G F VV
Sbjct: 75 PVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVV 134
Query: 270 DG-QFFEGSGRNKKLAKARAAQSALAAIFNL-----HLDQTPSRQPIPSEGLQL----HL 319
DG Q+ G G+NKK +++ AA+ AL + L + +T P P+E + L ++
Sbjct: 135 DGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYV 194
Query: 320 PQVLADA-------VSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVS 372
+V + +S++V +F L N S LA ++ +V+++
Sbjct: 195 SKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQ---HEVVAIG 251
Query: 373 TGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLEL-YLNNKDDQKRSIFQKSER 431
TG + + D G L+D HA + +RRSLLR+ Y QL L Y N ++SIF
Sbjct: 252 TGEYNYSQDIKPD-GRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPT 310
Query: 432 GGF-RLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGL 490
LK+N+ LY++ P GS Q +
Sbjct: 311 SNLLTLKQNINICLYMNQLP-----------------------------KGSAQIKSQLR 341
Query: 491 LSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGER 550
L+ S S F+ E H + + L DGV R
Sbjct: 342 LNPHSISAFEA---NEELCLHVAVEGKIYLTVYCPK----------------DGV---NR 379
Query: 551 LLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGD--HLSRAMYQRISN-- 606
+ +MS SDK+ RW V+G+QG+LLS F++P+Y SSI++G D L A+ QR+ +
Sbjct: 380 ISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDAL 439
Query: 607 IEDLPPLYTLNKPLLSGISNAEARQPGKAPNF-SVNWTVGDSAIEVINATTG-------- 657
LP Y +N+P +S + +A Q F S+NW GD ++E+++ +G
Sbjct: 440 TSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSPF 499
Query: 658 KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFT 717
K + ASRLCK A+ R+ + + LL + YH +K + YQ AK +L +
Sbjct: 500 KSGMSMASRLCKAAMLSRFNLLAKEAKKELLEA-----GTYHAAKCMSASYQEAKCKLKS 554
Query: 718 AFIKAGLGAWVEKPTEQDQFSL 739
+ G G+W+ K +QF++
Sbjct: 555 YLQQHGYGSWIVKSPCIEQFNM 576
>gi|226529650 adenosine deaminase domain containing 1
(testis-specific) isoform 2 [Homo sapiens]
Length = 565
Score = 132 bits (332), Expect = 1e-30
Identities = 149/561 (26%), Positives = 236/561 (42%), Gaps = 114/561 (20%)
Query: 223 PVLPPFPPPS--------GK-NPVMILNEL----RPGLKYDFLSESGESHAKSFVMSVVV 269
PVLPP P G+ NPV L++ R L +G F VV
Sbjct: 75 PVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVV 134
Query: 270 DG-QFFEGSGRNKKLAKARAAQSALAAIFNL-----HLDQTPSRQPIPSEGLQL----HL 319
DG Q+ G G+NKK +++ AA+ AL + L + +T P P+E + L ++
Sbjct: 135 DGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYV 194
Query: 320 PQVLADA-------VSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVS 372
+V + +S++V +F L N S LA ++ +V+++
Sbjct: 195 SKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQ---HEVVAIG 251
Query: 373 TGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERG 432
TG + + D G L+D HA + +RRSLL N ++SIF
Sbjct: 252 TGEYNYSQDIKPD-GRVLHDTHAVVTARRSLLS----------KNPAMMEKSIFCTEPTS 300
Query: 433 GF-RLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLL 491
LK+N+ LY++ P GS Q + L
Sbjct: 301 NLLTLKQNINICLYMNQLP-----------------------------KGSAQIKSQLRL 331
Query: 492 SDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERL 551
+ S S F+ E H + + L DGV R+
Sbjct: 332 NPHSISAFEA---NEELCLHVAVEGKIYLTVYCPK----------------DGV---NRI 369
Query: 552 LTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGD--HLSRAMYQRISN--I 607
+MS SDK+ RW V+G+QG+LLS F++P+Y SSI++G D L A+ QR+ +
Sbjct: 370 SSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDALT 429
Query: 608 EDLPPLYTLNKPLLSGISNAEARQPGKAPNF-SVNWTVGDSAIEVINATTG--------K 658
LP Y +N+P +S + +A Q F S+NW GD ++E+++ +G K
Sbjct: 430 SKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSPFK 489
Query: 659 DELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTA 718
+ ASRLCK A+ R+ + + LL + YH +K + YQ AK +L +
Sbjct: 490 SGMSMASRLCKAAMLSRFNLLAKEAKKELLEA-----GTYHAAKCMSASYQEAKCKLKSY 544
Query: 719 FIKAGLGAWVEKPTEQDQFSL 739
+ G G+W+ K +QF++
Sbjct: 545 LQQHGYGSWIVKSPCIEQFNM 565
>gi|223972690 adenosine deaminase domain containing 2 isoform 2
[Homo sapiens]
Length = 583
Score = 83.6 bits (205), Expect = 6e-16
Identities = 64/189 (33%), Positives = 97/189 (51%), Gaps = 17/189 (8%)
Query: 554 MSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHG-DHLSRAMYQR--ISNI--E 608
+S SDK+ARW V+G+ G+LL+ V P+Y +S+IL H LSRA++ R + ++
Sbjct: 394 LSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGP 453
Query: 609 DLPPLYTLNK-PLLSGISNAEAR-QPGKAPNFSVNWTVGDSAIEVINATTGKDE----LG 662
LPP Y L +G A + P S+NW++GD IEV++ TG+ + LG
Sbjct: 454 CLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALG 513
Query: 663 RASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKA 722
SRLCK ++R + + + + Y +K A YQ A+ +L +
Sbjct: 514 PPSRLCK----ASFLRAFHQAARAVGKPYLLALKTYEAAK--AGPYQEARRQLSLLLDQQ 567
Query: 723 GLGAWVEKP 731
GLGAW KP
Sbjct: 568 GLGAWPSKP 576
Score = 79.0 bits (193), Expect = 2e-14
Identities = 83/264 (31%), Positives = 114/264 (43%), Gaps = 22/264 (8%)
Query: 220 PPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVV--VDGQFFE-G 276
PP + P P V +L E L L + F SV +DG G
Sbjct: 100 PPAGLSLPLKDPPASQAVSLLTEYAASLGIFLLFREDQPPGPCFPFSVSAELDGVVCPAG 159
Query: 277 SGRNKKLAKARAAQSALAAIF----NLHLDQTPSRQPIPSEGLQLHLPQVLADAVSRLVL 332
+ +K AK +AA SAL I N QT SR P+ ++ L + LV
Sbjct: 160 TANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAPLSVENILTH--EQRCAALVS 217
Query: 333 GKFGDLTDNFSSPHARRKVLAGVVM------TTGTDVKDAKVISVSTGTKCINGEYMSDR 386
F L D S A + +AGV++ G + K++++ TG+ C G ++
Sbjct: 218 AGFDLLLDERSPYWACKGTVAGVILEREIPRARGHVKEIYKLVALGTGSSCCAG-WLEFS 276
Query: 387 GLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERG---GFRLKENVQFH 443
G L+DCH +I+RR+LLRFL+ QL L K + G F LK V H
Sbjct: 277 GQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLH 336
Query: 444 LYISTSPCGDAR-IFSPHEPILEG 466
LYIS +P G AR I+ P P EG
Sbjct: 337 LYISNTPKGAARDIYLP--PTSEG 358
>gi|223972688 adenosine deaminase domain containing 2 isoform 1
[Homo sapiens]
Length = 665
Score = 83.6 bits (205), Expect = 6e-16
Identities = 64/189 (33%), Positives = 97/189 (51%), Gaps = 17/189 (8%)
Query: 554 MSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHG-DHLSRAMYQR--ISNI--E 608
+S SDK+ARW V+G+ G+LL+ V P+Y +S+IL H LSRA++ R + ++
Sbjct: 476 LSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGP 535
Query: 609 DLPPLYTLNK-PLLSGISNAEAR-QPGKAPNFSVNWTVGDSAIEVINATTGKDE----LG 662
LPP Y L +G A + P S+NW++GD IEV++ TG+ + LG
Sbjct: 536 CLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALG 595
Query: 663 RASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKA 722
SRLCK ++R + + + + Y +K A YQ A+ +L +
Sbjct: 596 PPSRLCK----ASFLRAFHQAARAVGKPYLLALKTYEAAK--AGPYQEARRQLSLLLDQQ 649
Query: 723 GLGAWVEKP 731
GLGAW KP
Sbjct: 650 GLGAWPSKP 658
Score = 73.6 bits (179), Expect = 6e-13
Identities = 75/229 (32%), Positives = 105/229 (45%), Gaps = 30/229 (13%)
Query: 263 FVMSVVVDGQFFE-GSGRNKKLAKARAAQSALAAIF----NLHLDQTPSRQPIPSEGLQL 317
F +S +DG G+ +K AK +AA SAL I N QT SR P+ ++
Sbjct: 217 FSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAPLSVEN 276
Query: 318 HLPQVLADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTG--------TDVKDA--- 366
L + LV F L D S A + +AGV++ G T++ A
Sbjct: 277 ILTH--EQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSCTEIPRARGH 334
Query: 367 -----KVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQ 421
K++++ TG+ C G ++ G L+DCH +I+RR+LLRFL+ QL L
Sbjct: 335 VKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKG 393
Query: 422 KRSIFQKSERG---GFRLKENVQFHLYISTSPCGDAR-IFSPHEPILEG 466
K + G F LK V HLYIS +P G AR I+ P P EG
Sbjct: 394 KEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLP--PTSEG 440
>gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens]
Length = 502
Score = 80.5 bits (197), Expect = 5e-15
Identities = 67/218 (30%), Positives = 106/218 (48%), Gaps = 33/218 (15%)
Query: 547 QGERLLTMSCSDKIARWNVVGIQGSLL-SIFVEPIYFSSIILGSL-YHGDHLSRAMYQRI 604
+G+R +MSCSDK+ARWNV+G QG+LL + EPIY S++++G Y + + RA+ R
Sbjct: 290 RGDRTRSMSCSDKMARWNVLGCQGALLMHLLEEPIYLSAVVIGKCPYSQEAMQRALIGRC 349
Query: 605 SNIEDLP------PLYTLNKPLL-----SGISNAEARQPGKAP--NFSVNWT-VGDSAIE 650
N+ LP L L LL S + A PG+ +++W+ V + ++
Sbjct: 350 QNVSALPKGFGVQELKILQSDLLFEQSRSAVQAKRADSPGRLVPCGAAISWSAVPEQPLD 409
Query: 651 VI-----NATTGK--DELGRASRLCKHALYCRWMRVHGKVP----SHLLRSKITKPNVYH 699
V TT K L S++ K L+ + ++ ++ H LR + K + Y
Sbjct: 410 VTANGFPQGTTKKTIGSLQARSQISKVELFRSFQKLLSRIARDKWPHSLR--VQKLDTYQ 467
Query: 700 ESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQF 737
E K AA YQ A ++ K G+W+ P + QF
Sbjct: 468 EYKEAASSYQEA----WSTLRKQVFGSWIRNPPDYHQF 501
Score = 72.0 bits (175), Expect = 2e-12
Identities = 45/120 (37%), Positives = 69/120 (57%), Gaps = 9/120 (7%)
Query: 367 KVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIF 426
+++S+ TGTKCI M G LND HAE+I+RRS R+L QL+L K+D SIF
Sbjct: 60 EIVSMGTGTKCIGQSKMRKNGDILNDSHAEVIARRSFQRYLLHQLQLAATLKED---SIF 116
Query: 427 -QKSERGGFRLKENVQFHLYISTSPCGDARIFSPHEPILE-GSRSYTQAGVQWCNHGSLQ 484
+++G ++L+ ++ F + S +PCGDA I P+LE + W N+ S++
Sbjct: 117 VPGTQKGVWKLRRDLIFVFFSSHTPCGDASII----PMLEFEDQPCCPVFRNWANNSSVE 172
>gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 72.8 bits (177), Expect = 1e-12
Identities = 67/227 (29%), Positives = 94/227 (41%), Gaps = 40/227 (17%)
Query: 95 YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLA 154
Y LL G H P F V V G GP+KK AK AAE AL+ HL
Sbjct: 27 YDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALK-----------HLK 75
Query: 155 MGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVP 214
G L + +S F+ ++ + P + + +A+PVP
Sbjct: 76 GGSMLEPALEDSSS--------FSPLDSSLPEDIPVFTA-------------AAAATPVP 114
Query: 215 ASL--AQPPLPVLPPFPPPSGK-NPVMILNEL--RPGLK---YDFLSESGESHAKSFVMS 266
+ + PP+ + PP P + NPV L EL + G + Y ESG +H K F M+
Sbjct: 115 SVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMT 174
Query: 267 VVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQTPSRQPIPSE 313
V+ GSG +KKLAK AA L + + LD + P +
Sbjct: 175 CRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDD 221
Score = 38.1 bits (87), Expect = 0.030
Identities = 19/46 (41%), Positives = 27/46 (58%)
Query: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKAL 139
+YT+ ++GP H F M+ V + GSG +KK AK +AA K L
Sbjct: 156 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML 201
>gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 72.8 bits (177), Expect = 1e-12
Identities = 67/227 (29%), Positives = 94/227 (41%), Gaps = 40/227 (17%)
Query: 95 YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLA 154
Y LL G H P F V V G GP+KK AK AAE AL+ HL
Sbjct: 48 YDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALK-----------HLK 96
Query: 155 MGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVP 214
G L + +S F+ ++ + P + + +A+PVP
Sbjct: 97 GGSMLEPALEDSSS--------FSPLDSSLPEDIPVFTA-------------AAAATPVP 135
Query: 215 ASL--AQPPLPVLPPFPPPSGK-NPVMILNEL--RPGLK---YDFLSESGESHAKSFVMS 266
+ + PP+ + PP P + NPV L EL + G + Y ESG +H K F M+
Sbjct: 136 SVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMT 195
Query: 267 VVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQTPSRQPIPSE 313
V+ GSG +KKLAK AA L + + LD + P +
Sbjct: 196 CRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDD 242
Score = 38.1 bits (87), Expect = 0.030
Identities = 19/46 (41%), Positives = 27/46 (58%)
Query: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKAL 139
+YT+ ++GP H F M+ V + GSG +KK AK +AA K L
Sbjct: 177 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML 222
>gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 72.8 bits (177), Expect = 1e-12
Identities = 67/227 (29%), Positives = 94/227 (41%), Gaps = 40/227 (17%)
Query: 95 YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLA 154
Y LL G H P F V V G GP+KK AK AAE AL+ HL
Sbjct: 27 YDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALK-----------HLK 75
Query: 155 MGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVP 214
G L + +S F+ ++ + P + + +A+PVP
Sbjct: 76 GGSMLEPALEDSSS--------FSPLDSSLPEDIPVFTA-------------AAAATPVP 114
Query: 215 ASL--AQPPLPVLPPFPPPSGK-NPVMILNEL--RPGLK---YDFLSESGESHAKSFVMS 266
+ + PP+ + PP P + NPV L EL + G + Y ESG +H K F M+
Sbjct: 115 SVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMT 174
Query: 267 VVVDGQFFEGSGRNKKLAKARAAQSALAAIFNLHLDQTPSRQPIPSE 313
V+ GSG +KKLAK AA L + + LD + P +
Sbjct: 175 CRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDD 221
Score = 38.1 bits (87), Expect = 0.030
Identities = 19/46 (41%), Positives = 27/46 (58%)
Query: 94 QYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKAL 139
+YT+ ++GP H F M+ V + GSG +KK AK +AA K L
Sbjct: 156 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML 201
>gi|82659089 staufen isoform a [Homo sapiens]
Length = 496
Score = 59.7 bits (143), Expect = 1e-08
Identities = 71/254 (27%), Positives = 102/254 (40%), Gaps = 48/254 (18%)
Query: 103 PVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP---------------- 146
PV L+ + + V GQ F G G T++ AK AA KALR P
Sbjct: 40 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 99
Query: 147 -NASEA----HLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFS 201
N SE +A+ R L VN + + P + N F T K +VG S
Sbjct: 100 LNKSEISQVFEIALKRNLPVNFEVARESG--PPHMKN-FVT--KVSVGEFVGEGEGKSKK 154
Query: 202 SSGDLSLSA--------SPVPA------SLAQPPLPVLPPFPPP---SGKNPVMILNELR 244
S + A P+PA + + P++ P P G NP+ L +++
Sbjct: 155 ISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQ 214
Query: 245 PGLK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNL 299
K Y L+E G + FVM V V EG+G NKK+AK AA++ L +
Sbjct: 215 QAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFK 274
Query: 300 HLDQTPSRQPIPSE 313
P++ + SE
Sbjct: 275 VPQAQPTKPALKSE 288
Score = 40.0 bits (92), Expect = 0.008
Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Query: 79 PKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAE 136
P + L Q+ + K + YTLL++ G FVM V+V EG+G KK AK +AAE
Sbjct: 206 PISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAE 265
Query: 137 KAL 139
L
Sbjct: 266 NML 268
Score = 33.5 bits (75), Expect = 0.73
Identities = 18/54 (33%), Positives = 27/54 (50%)
Query: 93 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146
+ + + ++GP H FV V V V EG G +KK +K +AA L + P
Sbjct: 119 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 172
>gi|82659087 staufen isoform b [Homo sapiens]
Length = 577
Score = 59.7 bits (143), Expect = 1e-08
Identities = 71/254 (27%), Positives = 102/254 (40%), Gaps = 48/254 (18%)
Query: 103 PVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP---------------- 146
PV L+ + + V GQ F G G T++ AK AA KALR P
Sbjct: 121 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 180
Query: 147 -NASEA----HLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFS 201
N SE +A+ R L VN + + P + N F T K +VG S
Sbjct: 181 LNKSEISQVFEIALKRNLPVNFEVARESG--PPHMKN-FVT--KVSVGEFVGEGEGKSKK 235
Query: 202 SSGDLSLSA--------SPVPA------SLAQPPLPVLPPFPPP---SGKNPVMILNELR 244
S + A P+PA + + P++ P P G NP+ L +++
Sbjct: 236 ISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQ 295
Query: 245 PGLK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNL 299
K Y L+E G + FVM V V EG+G NKK+AK AA++ L +
Sbjct: 296 QAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFK 355
Query: 300 HLDQTPSRQPIPSE 313
P++ + SE
Sbjct: 356 VPQAQPTKPALKSE 369
Score = 40.0 bits (92), Expect = 0.008
Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Query: 79 PKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAE 136
P + L Q+ + K + YTLL++ G FVM V+V EG+G KK AK +AAE
Sbjct: 287 PISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAE 346
Query: 137 KAL 139
L
Sbjct: 347 NML 349
Score = 33.5 bits (75), Expect = 0.73
Identities = 18/54 (33%), Positives = 27/54 (50%)
Query: 93 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146
+ + + ++GP H FV V V V EG G +KK +K +AA L + P
Sbjct: 200 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 253
>gi|82659085 staufen isoform a [Homo sapiens]
Length = 496
Score = 59.7 bits (143), Expect = 1e-08
Identities = 71/254 (27%), Positives = 102/254 (40%), Gaps = 48/254 (18%)
Query: 103 PVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP---------------- 146
PV L+ + + V GQ F G G T++ AK AA KALR P
Sbjct: 40 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 99
Query: 147 -NASEA----HLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFS 201
N SE +A+ R L VN + + P + N F T K +VG S
Sbjct: 100 LNKSEISQVFEIALKRNLPVNFEVARESG--PPHMKN-FVT--KVSVGEFVGEGEGKSKK 154
Query: 202 SSGDLSLSA--------SPVPA------SLAQPPLPVLPPFPPP---SGKNPVMILNELR 244
S + A P+PA + + P++ P P G NP+ L +++
Sbjct: 155 ISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQ 214
Query: 245 PGLK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNL 299
K Y L+E G + FVM V V EG+G NKK+AK AA++ L +
Sbjct: 215 QAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFK 274
Query: 300 HLDQTPSRQPIPSE 313
P++ + SE
Sbjct: 275 VPQAQPTKPALKSE 288
Score = 40.0 bits (92), Expect = 0.008
Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Query: 79 PKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAE 136
P + L Q+ + K + YTLL++ G FVM V+V EG+G KK AK +AAE
Sbjct: 206 PISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAE 265
Query: 137 KAL 139
L
Sbjct: 266 NML 268
Score = 33.5 bits (75), Expect = 0.73
Identities = 18/54 (33%), Positives = 27/54 (50%)
Query: 93 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146
+ + + ++GP H FV V V V EG G +KK +K +AA L + P
Sbjct: 119 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 172
>gi|82659083 staufen isoform a [Homo sapiens]
Length = 496
Score = 59.7 bits (143), Expect = 1e-08
Identities = 71/254 (27%), Positives = 102/254 (40%), Gaps = 48/254 (18%)
Query: 103 PVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP---------------- 146
PV L+ + + V GQ F G G T++ AK AA KALR P
Sbjct: 40 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 99
Query: 147 -NASEA----HLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFS 201
N SE +A+ R L VN + + P + N F T K +VG S
Sbjct: 100 LNKSEISQVFEIALKRNLPVNFEVARESG--PPHMKN-FVT--KVSVGEFVGEGEGKSKK 154
Query: 202 SSGDLSLSA--------SPVPA------SLAQPPLPVLPPFPPP---SGKNPVMILNELR 244
S + A P+PA + + P++ P P G NP+ L +++
Sbjct: 155 ISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQ 214
Query: 245 PGLK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNL 299
K Y L+E G + FVM V V EG+G NKK+AK AA++ L +
Sbjct: 215 QAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFK 274
Query: 300 HLDQTPSRQPIPSE 313
P++ + SE
Sbjct: 275 VPQAQPTKPALKSE 288
Score = 40.0 bits (92), Expect = 0.008
Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Query: 79 PKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAE 136
P + L Q+ + K + YTLL++ G FVM V+V EG+G KK AK +AAE
Sbjct: 206 PISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAE 265
Query: 137 KAL 139
L
Sbjct: 266 NML 268
Score = 33.5 bits (75), Expect = 0.73
Identities = 18/54 (33%), Positives = 27/54 (50%)
Query: 93 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146
+ + + ++GP H FV V V V EG G +KK +K +AA L + P
Sbjct: 119 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 172
>gi|82659091 staufen isoform c [Homo sapiens]
Length = 502
Score = 56.2 bits (134), Expect = 1e-07
Identities = 73/258 (28%), Positives = 103/258 (39%), Gaps = 50/258 (19%)
Query: 103 PVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP---------------- 146
PV L+ + + V GQ F G G T++ AK AA KALR P
Sbjct: 40 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 99
Query: 147 -NASEA----HLAMGRTLSVNTD-FTSDQA---DFPDTLFNGFETPDKAEPPFYVGSNGD 197
N SE +A+ R L VN + F Q P + N F T K +VG
Sbjct: 100 LNKSEISQVFEIALKRNLPVNFESFPLKQVARESGPPHMKN-FVT--KVSVGEFVGEGEG 156
Query: 198 DSFSSSGDLSLSA--------SPVPA------SLAQPPLPVLPPFPPPS---GKNPVMIL 240
S S + A P+PA + + P++ P P G NP+ L
Sbjct: 157 KSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRL 216
Query: 241 NELRPGLK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAA 295
+++ K Y L+E G + FVM V V EG+G NKK+AK AA++ L
Sbjct: 217 AQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEI 276
Query: 296 IFNLHLDQTPSRQPIPSE 313
+ P++ + SE
Sbjct: 277 LGFKVPQAQPTKPALKSE 294
Score = 40.0 bits (92), Expect = 0.008
Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Query: 79 PKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAE 136
P + L Q+ + K + YTLL++ G FVM V+V EG+G KK AK +AAE
Sbjct: 212 PISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAE 271
Query: 137 KAL 139
L
Sbjct: 272 NML 274
Score = 32.7 bits (73), Expect = 1.2
Identities = 18/47 (38%), Positives = 24/47 (51%)
Query: 100 QTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146
++GP H FV V V V EG G +KK +K +AA L + P
Sbjct: 132 ESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 178
>gi|7657625 staufen homolog 2 [Homo sapiens]
Length = 479
Score = 52.8 bits (125), Expect = 1e-06
Identities = 57/232 (24%), Positives = 88/232 (37%), Gaps = 43/232 (18%)
Query: 105 HAP---LFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQ--FPNASEAHLAMGRTL 159
H P +F + + V F G G T++ A+ +AA KAL++ P S + G+ +
Sbjct: 107 HCPVPKIFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDM 166
Query: 160 SVNTDFTSDQADF------PDTLFNGFETPDKAEPPFYVG-----SNGDDSFSSSGDLSL 208
+ D + + FE ++ PP S G+ S G+
Sbjct: 167 DDDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKK 226
Query: 209 SASPVPASLAQPPLPVLPPFPPPS----------------------GKNPVMILNELRPG 246
+ A+ L LPP P G NP+ L +++
Sbjct: 227 LSKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQA 286
Query: 247 LK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSAL 293
K Y LSE G + FVM V V + G+G NKK+AK AA++ L
Sbjct: 287 KKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAML 338
Score = 43.5 bits (101), Expect = 7e-04
Identities = 34/86 (39%), Positives = 44/86 (51%), Gaps = 10/86 (11%)
Query: 64 KYRLKKRRKT---PGP-----VLPKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSV 113
K KKR KT GP + P + L Q+ + K + Y LLS+ G FVM V
Sbjct: 253 KLFFKKRPKTIVKAGPEYGQGMNPISRLAQIQQAKKEKEPDYVLLSERGMPRRREFVMQV 312
Query: 114 EVNGQVFEGSGPTKKKAKLHAAEKAL 139
+V +V G+GP KK AK +AAE L
Sbjct: 313 KVGNEVATGTGPNKKIAKKNAAEAML 338
Score = 41.2 bits (95), Expect = 0.004
Identities = 22/53 (41%), Positives = 30/53 (56%)
Query: 247 LKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNL 299
+ ++ + ESG H KSFV V V EG G +KKL+K RAA + L + L
Sbjct: 191 VSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKL 243
Score = 33.9 bits (76), Expect = 0.56
Identities = 17/54 (31%), Positives = 27/54 (50%)
Query: 93 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146
+ + ++ ++GP H FV V V EG G +KK +K AA L+ + P
Sbjct: 191 VSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQELKKLP 244
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,546,150
Number of Sequences: 37866
Number of extensions: 1660686
Number of successful extensions: 8661
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 91
Number of HSP's that attempted gapping in prelim test: 7932
Number of HSP's gapped (non-prelim): 672
length of query: 741
length of database: 18,247,518
effective HSP length: 110
effective length of query: 631
effective length of database: 14,082,258
effective search space: 8885904798
effective search space used: 8885904798
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.