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Search of human proteins with 7662092
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7662092 zinc finger protein 536 [Homo sapiens]
(1300 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7662092 zinc finger protein 536 [Homo sapiens] 2649 0.0
gi|7662010 zinc finger protein 516 [Homo sapiens] 352 1e-96
gi|5730124 zinc finger protein 217 [Homo sapiens] 266 7e-71
gi|156416026 zinc finger protein 219 [Homo sapiens] 242 1e-63
gi|156415998 zinc finger protein 219 [Homo sapiens] 242 1e-63
gi|156415996 zinc finger protein 219 [Homo sapiens] 242 1e-63
gi|138175817 zinc finger protein 236 [Homo sapiens] 115 4e-25
gi|32698786 zinc finger protein 227 [Homo sapiens] 100 7e-21
gi|153791350 replication initiator 1 isoform 1 [Homo sapiens] 100 1e-20
gi|153792539 replication initiator 1 isoform 1 [Homo sapiens] 100 1e-20
gi|153792647 replication initiator 1 isoform 3 [Homo sapiens] 100 1e-20
gi|153791994 replication initiator 1 isoform 1 [Homo sapiens] 100 1e-20
gi|104294877 zinc finger protein 229 [Homo sapiens] 97 1e-19
gi|14249488 zinc finger and SCAN domain containing 10 [Homo sapi... 97 1e-19
gi|10047144 sal-like 4 [Homo sapiens] 96 2e-19
gi|110347439 zinc finger protein 225 [Homo sapiens] 95 4e-19
gi|197313746 zinc finger protein 502 [Homo sapiens] 92 4e-18
gi|197313744 zinc finger protein 502 [Homo sapiens] 92 4e-18
gi|197313742 zinc finger protein 502 [Homo sapiens] 92 4e-18
gi|110815807 zinc finger protein 169 [Homo sapiens] 91 9e-18
gi|46409310 zinc finger protein 467 [Homo sapiens] 91 9e-18
gi|4508035 zinc finger protein 7 [Homo sapiens] 90 1e-17
gi|40807465 zinc finger protein 341 [Homo sapiens] 90 2e-17
gi|61676193 zinc finger protein 260 [Homo sapiens] 89 2e-17
gi|134142822 zinc finger protein 133 [Homo sapiens] 88 5e-17
gi|27545332 zinc finger protein 133 [Homo sapiens] 88 5e-17
gi|170932473 zinc finger protein 786 [Homo sapiens] 88 5e-17
gi|34303941 zinc finger protein 567 [Homo sapiens] 88 5e-17
gi|116256460 zinc finger protein 775 [Homo sapiens] 88 6e-17
gi|209862791 zinc finger protein 90 [Homo sapiens] 87 8e-17
>gi|7662092 zinc finger protein 536 [Homo sapiens]
Length = 1300
Score = 2649 bits (6865), Expect = 0.0
Identities = 1300/1300 (100%), Positives = 1300/1300 (100%)
Query: 1 MEEASLCLGVSSAEPEAEPHLSGPVLNGQYAMSQKLHQITSQLSHAFPELHPRPNPEEKP 60
MEEASLCLGVSSAEPEAEPHLSGPVLNGQYAMSQKLHQITSQLSHAFPELHPRPNPEEKP
Sbjct: 1 MEEASLCLGVSSAEPEAEPHLSGPVLNGQYAMSQKLHQITSQLSHAFPELHPRPNPEEKP 60
Query: 61 PASLEEKAHVPMSGQPMGSQMALLANQLGREVDTSLNGRVDLQQFLNGQNLGIMSQMSDI 120
PASLEEKAHVPMSGQPMGSQMALLANQLGREVDTSLNGRVDLQQFLNGQNLGIMSQMSDI
Sbjct: 61 PASLEEKAHVPMSGQPMGSQMALLANQLGREVDTSLNGRVDLQQFLNGQNLGIMSQMSDI 120
Query: 121 EDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
EDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH
Sbjct: 121 EDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
Query: 181 KLGNLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTL 240
KLGNLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTL
Sbjct: 181 KLGNLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTL 240
Query: 241 ALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRILHKPY 300
ALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRILHKPY
Sbjct: 241 ALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRILHKPY 300
Query: 301 KCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFL 360
KCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFL
Sbjct: 301 KCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFL 360
Query: 361 KGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKNKSPSDPEVPVPMGGMSQ 420
KGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKNKSPSDPEVPVPMGGMSQ
Sbjct: 361 KGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKNKSPSDPEVPVPMGGMSQ 420
Query: 421 EAHANLYSRYLSCLQSGFMTPDKAGLSEPSQLYGKGELPMKEKEALGKLLSPISSMAHGV 480
EAHANLYSRYLSCLQSGFMTPDKAGLSEPSQLYGKGELPMKEKEALGKLLSPISSMAHGV
Sbjct: 421 EAHANLYSRYLSCLQSGFMTPDKAGLSEPSQLYGKGELPMKEKEALGKLLSPISSMAHGV 480
Query: 481 PEGDKHSLLGCLNLVPPLKSSCIERLQAAAKAAEMDPVNSYQAWQLMARGMAMEHGFLSK 540
PEGDKHSLLGCLNLVPPLKSSCIERLQAAAKAAEMDPVNSYQAWQLMARGMAMEHGFLSK
Sbjct: 481 PEGDKHSLLGCLNLVPPLKSSCIERLQAAAKAAEMDPVNSYQAWQLMARGMAMEHGFLSK 540
Query: 541 EHPLQRNHEDTLANAGVLFDKEKREYVLVGADGSKQKMPADLVHSTKVGSQRDLPSKLDP 600
EHPLQRNHEDTLANAGVLFDKEKREYVLVGADGSKQKMPADLVHSTKVGSQRDLPSKLDP
Sbjct: 541 EHPLQRNHEDTLANAGVLFDKEKREYVLVGADGSKQKMPADLVHSTKVGSQRDLPSKLDP 600
Query: 601 LESSRDFLSHGLNQTLEYNLQGPGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGE 660
LESSRDFLSHGLNQTLEYNLQGPGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGE
Sbjct: 601 LESSRDFLSHGLNQTLEYNLQGPGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGE 660
Query: 661 EDGLHVGLDERRGSGSDQESQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSP 720
EDGLHVGLDERRGSGSDQESQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSP
Sbjct: 661 EDGLHVGLDERRGSGSDQESQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSP 720
Query: 721 SSSDIGEEAGRSAGVQQPALLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYK 780
SSSDIGEEAGRSAGVQQPALLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYK
Sbjct: 721 SSSDIGEEAGRSAGVQQPALLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYK 780
Query: 781 CPHCDYAGTQSASLKYHLERHHRERQNGAGPLSGQPPNQDHKDEMSSKASLFIRPDILRG 840
CPHCDYAGTQSASLKYHLERHHRERQNGAGPLSGQPPNQDHKDEMSSKASLFIRPDILRG
Sbjct: 781 CPHCDYAGTQSASLKYHLERHHRERQNGAGPLSGQPPNQDHKDEMSSKASLFIRPDILRG 840
Query: 841 AFKGLPGIDFRGGPASQQWTSGVLSSGDHSGQATGMSSEVPSDALKGTDLPSKSTHFSEI 900
AFKGLPGIDFRGGPASQQWTSGVLSSGDHSGQATGMSSEVPSDALKGTDLPSKSTHFSEI
Sbjct: 841 AFKGLPGIDFRGGPASQQWTSGVLSSGDHSGQATGMSSEVPSDALKGTDLPSKSTHFSEI 900
Query: 901 GRAYQSIVSNGVNFQGSLQAFMDSFVLSSLKKEKDMKDKALADPPSMKVHGVDGGEEKPS 960
GRAYQSIVSNGVNFQGSLQAFMDSFVLSSLKKEKDMKDKALADPPSMKVHGVDGGEEKPS
Sbjct: 901 GRAYQSIVSNGVNFQGSLQAFMDSFVLSSLKKEKDMKDKALADPPSMKVHGVDGGEEKPS 960
Query: 961 GKSSQRKSEKSQYEPLDLSVRPDAASLPGSSVTVQDSIAWHGCLFCAFTTSSMELMALHL 1020
GKSSQRKSEKSQYEPLDLSVRPDAASLPGSSVTVQDSIAWHGCLFCAFTTSSMELMALHL
Sbjct: 961 GKSSQRKSEKSQYEPLDLSVRPDAASLPGSSVTVQDSIAWHGCLFCAFTTSSMELMALHL 1020
Query: 1021 QANHLGKAKRKDNTIGVTVNCKDQAREASKMALLPSLQSNKDLGLSNMISSLDSASEKMA 1080
QANHLGKAKRKDNTIGVTVNCKDQAREASKMALLPSLQSNKDLGLSNMISSLDSASEKMA
Sbjct: 1021 QANHLGKAKRKDNTIGVTVNCKDQAREASKMALLPSLQSNKDLGLSNMISSLDSASEKMA 1080
Query: 1081 QGQLKETLGEQKSGAWTGHVDPAFCNFPSDFYKQFGVYPGMVGSGASSSCPNKEPDGKAH 1140
QGQLKETLGEQKSGAWTGHVDPAFCNFPSDFYKQFGVYPGMVGSGASSSCPNKEPDGKAH
Sbjct: 1081 QGQLKETLGEQKSGAWTGHVDPAFCNFPSDFYKQFGVYPGMVGSGASSSCPNKEPDGKAH 1140
Query: 1141 SEEDVPILIPETTSKNTTDDLSDIASSEDMDSSKGENNDEEDVETEPEMMTKPLSALSKD 1200
SEEDVPILIPETTSKNTTDDLSDIASSEDMDSSKGENNDEEDVETEPEMMTKPLSALSKD
Sbjct: 1141 SEEDVPILIPETTSKNTTDDLSDIASSEDMDSSKGENNDEEDVETEPEMMTKPLSALSKD 1200
Query: 1201 SSSDGGDSLQPTGTSQPVQGLVSPLSQAPEKQWHSQGLLQAQDPLAGLPKPERGPQSLDK 1260
SSSDGGDSLQPTGTSQPVQGLVSPLSQAPEKQWHSQGLLQAQDPLAGLPKPERGPQSLDK
Sbjct: 1201 SSSDGGDSLQPTGTSQPVQGLVSPLSQAPEKQWHSQGLLQAQDPLAGLPKPERGPQSLDK 1260
Query: 1261 PMNMLSVLRAYSSDGLAAFNGLASSTANSGCIKRPDLCGK 1300
PMNMLSVLRAYSSDGLAAFNGLASSTANSGCIKRPDLCGK
Sbjct: 1261 PMNMLSVLRAYSSDGLAAFNGLASSTANSGCIKRPDLCGK 1300
>gi|7662010 zinc finger protein 516 [Homo sapiens]
Length = 1163
Score = 352 bits (903), Expect = 1e-96
Identities = 233/621 (37%), Positives = 311/621 (50%), Gaps = 53/621 (8%)
Query: 121 EDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
E D K + C +CGK F F S LS HMR HTGEKP+KCPYCDHRA+QKGNLKIH+R+H
Sbjct: 25 EVDGDKATCHTCCICGKSFPFQSSLSQHMRKHTGEKPYKCPYCDHRASQKGNLKIHIRSH 84
Query: 181 KLGNLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTL 240
+ G L +G E L +R + + P A
Sbjct: 85 RTGTLIQGHEPEAGEAPL-------GEMRASEGLDACASPTKSASACNRLLNGASQADGA 137
Query: 241 ALQANHSVPDVAHPVPSPKPASVQEDAVAPA---AGFRCTFCKGKFKKREELDRHIRILH 297
+ S D + + A AP A +C+FCK +F+++++L+ H+ H
Sbjct: 138 RVLNGASQADSGRVLLRSSKKGAEGSACAPGEAKAAVQCSFCKSQFERKKDLELHVHQAH 197
Query: 298 KPYKCTLCDFAASQEEELISHVEKAHITAE---SAQGQGPNGGGEQSANEFRCEVCGQVF 354
KP+KC LC +A +EE L+SH+E+ HITA+ S + NG E S EF CEVCGQ F
Sbjct: 198 KPFKCRLCSYATLREESLLSHIERDHITAQGPGSGEACVENGKPELSPGEFPCEVCGQAF 257
Query: 355 SQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKNKSPSDPEVPVP 414
SQ WFLK HM+KH+ SF+H C ICGRRFKEPWFLKNHMK H K KN+ S+ +
Sbjct: 258 SQTWFLKAHMKKHRGSFDHGCHICGRRFKEPWFLKNHMKAHGPKTGSKNRPKSELDPIAT 317
Query: 415 MGGMSQE--AHANLYSRYLSCLQSGFMTPDKAGLSEPSQLYGKGELPMKEKEALGKLLSP 472
+ + QE A L S Y C + G + + L+ + ++ + E + +P
Sbjct: 318 INNVVQEEVIVAGL-SLYEVCAKCGNLFTNLDSLNAHNAIHRRVE--------ASRTRAP 368
Query: 473 ISSMAHGVPEGDKHSLLGCLNLVPPLKSSCIERLQAAAKAAEMDPVNSYQAWQLMARGMA 532
A G P K L CLNL P QA + AE+DPVNSYQAWQL RG
Sbjct: 369 AEEGAEG-PSDTKQFFLQCLNLRPSAAGDSCPGTQAGRRVAELDPVNSYQAWQLATRGKV 427
Query: 533 MEHGFLSKEHPLQRNHEDTLANAGVLFDKEKREYVLVGADGSK--QKMPADLVHSTKVGS 590
E L+ D V FDK++REYVLV + K Q PA K S
Sbjct: 428 AE-----PAEYLKYGAWDEALAGDVAFDKDRREYVLVSQEKRKREQDAPAAQGPPRKRAS 482
Query: 591 QRDLPS---KLDPLESSRDFLSHGLNQTLEYNLQGPGNMKEKPTECPDCGRVFRTYHQVV 647
P+ LDP ++R + QG K +EC +CG++FRTYHQ+V
Sbjct: 483 GPGDPAPAGHLDPRSAARP-----NRRAAATTGQG------KSSECFECGKIFRTYHQMV 531
Query: 648 VHSRVHKRDRK-GEEDGLHVGLDERRGSGSDQESQSVSRSTTPGSSNVTEESGVGGGLSQ 706
+HSRVH+R R+ + DG R GS E S S+ ++PGS+ +S G GL+
Sbjct: 532 LHSRVHRRARRERDSDGDRAA---RARCGSLSEGDSASQPSSPGSACAAADS-PGSGLAD 587
Query: 707 TGSAQEDSPHPSSPSSSDIGE 727
A EDS +P + G+
Sbjct: 588 --EAAEDSGEEGAPEPAPGGQ 606
Score = 65.5 bits (158), Expect = 3e-10
Identities = 54/202 (26%), Positives = 82/202 (40%), Gaps = 19/202 (9%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRD---RKGEEDGLHVGLDERRGSGSDQESQSVS 684
EKP +CP C + +H R H+ + E + L E R S S +
Sbjct: 59 EKPYKCPYCDHRASQKGNLKIHIRSHRTGTLIQGHEPEAGEAPLGEMRASEGLDACASPT 118
Query: 685 RSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDR 744
+S + + + S G G++Q DS SS E + + G + A+
Sbjct: 119 KSASACNRLLNGASQADGARVLNGASQADSGRVLLRSSKKGAEGSACAPGEAKAAV---- 174
Query: 745 SLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRE 804
C +C F L++H +H KP+KC C YA + SL H+ER H
Sbjct: 175 -------QCSFCKSQFERKKDLELH--VHQAHKPFKCRLCSYATLREESLLSHIERDHIT 225
Query: 805 RQNGAGPLSGQPPNQDHKDEMS 826
Q GP SG+ ++ K E+S
Sbjct: 226 AQ---GPGSGEACVENGKPELS 244
Score = 65.1 bits (157), Expect = 4e-10
Identities = 29/66 (43%), Positives = 38/66 (57%), Gaps = 1/66 (1%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQ-NGAGP 811
C CGK+F L H+R HTGEKPYKCP+CD+ +Q +LK H+ H G P
Sbjct: 36 CCICGKSFPFQSSLSQHMRKHTGEKPYKCPYCDHRASQKGNLKIHIRSHRTGTLIQGHEP 95
Query: 812 LSGQPP 817
+G+ P
Sbjct: 96 EAGEAP 101
Score = 46.2 bits (108), Expect = 2e-04
Identities = 63/285 (22%), Positives = 108/285 (37%), Gaps = 29/285 (10%)
Query: 752 DCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQNGAGP 811
+C CGK FRT H + +H R+H + + D A + + G+
Sbjct: 516 ECFECGKIFRTYHQMVLHSRVHRRARRERDSDGDRAARARCGSLSEGDSASQPSSPGSAC 575
Query: 812 LSGQPPNQDHKDEMSSKASLFIRPDILRGAFKGLPGIDFRGGPASQQWTSGVLSSGDHSG 871
+ P DE + + GA + PG R S++ TS LSSGD S
Sbjct: 576 AAADSPGSGLADEAAEDSG-------EEGAPEPAPGGQPRRCCFSEEVTSTELSSGDQSH 628
Query: 872 QATGMSSEVPSDALKGTDLPSKSTHFSEIGRAYQSIVSNGVNFQGSLQAFMDSFVLSSLK 931
+ +SE + G + S + + + + S+ M +F K
Sbjct: 629 KMGDNASERDT----GESKAGIAASVSILENSSRETSRRQEQHRFSMDLKMPAF---HPK 681
Query: 932 KEKDMKDKALADPPSMKVHGVDGGEEKPSGKSSQ----------RKSEKSQYEPLDLSVR 981
+E + + P S G +G P+ K S +++ PLDLS R
Sbjct: 682 QEVPVPGDGVEFPSST---GAEGQTGHPAEKLSDLHNKEHSGGGKRALAPDLMPLDLSAR 738
Query: 982 P--DAASLPGSSVTVQDSIAWHGCLFCAFTTSSMELMALHLQANH 1024
D S ++ ++Q ++ H C +C+ T E++ +H + H
Sbjct: 739 STRDDPSNKETASSLQAALVVHPCPYCSHKTYYPEVLWMHKRIWH 783
Score = 41.2 bits (95), Expect = 0.007
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
Query: 331 GQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKN 390
G+G G++ A C +CG+ F L HMRKH + C C R + LK
Sbjct: 21 GRGHEVDGDK-ATCHTCCICGKSFPFQSSLSQHMRKHTGEKPYKCPYCDHRASQKGNLKI 79
Query: 391 HMKVHLNKLSVKNKSPSDPEVPV 413
H++ H ++ P E P+
Sbjct: 80 HIRSHRTGTLIQGHEPEAGEAPL 102
Score = 34.7 bits (78), Expect = 0.61
Identities = 15/49 (30%), Positives = 23/49 (46%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERH 801
C CG+ F + LK H++ H G + C C + LK H++ H
Sbjct: 250 CEVCGQAFSQTWFLKAHMKKHRGSFDHGCHICGRRFKEPWFLKNHMKAH 298
Score = 33.5 bits (75), Expect = 1.4
Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 13/78 (16%)
Query: 308 AASQEEEL-ISHVEKAHITAESA---QGQGPNGGG---------EQSANEFRCEVCGQVF 354
A E+ L I ++ K +I + A QG G +G G + EF C CG+ F
Sbjct: 1048 AEGHEKRLDILNIFKTYIPKDFATLYQGWGVSGPGLEHRGTLRTQARPGEFVCIECGKSF 1107
Query: 355 SQAWFLKGHMRKHKDSFE 372
Q L+ HMR H FE
Sbjct: 1108 HQPGHLRAHMRAHSVVFE 1125
>gi|5730124 zinc finger protein 217 [Homo sapiens]
Length = 1048
Score = 266 bits (681), Expect = 7e-71
Identities = 231/817 (28%), Positives = 355/817 (43%), Gaps = 116/817 (14%)
Query: 262 SVQEDAVAPAAGFR---CTFCKGKFKKREELDRHIRILHKPYKCTLCDFAASQ-EEELIS 317
+ QE V G+ C FC F E+L++H+ + H+P TLC+ A + E E +S
Sbjct: 50 ATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQHRP---TLCEPAVLRVEAEYLS 106
Query: 318 HVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQI 377
++K+ + E P NEF CEVCGQ F A+ ++ HMR HKDSF + C +
Sbjct: 107 PLDKSQVRTE------PPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNM 160
Query: 378 CGRRFKEPWFLKNHMKVHLNKLSVKNKSPSDPEVPVPMGGMSQEAHA--NLYSRYLSCLQ 435
CGRRFKEPWFLKNHM+ H K ++K E + HA ++ S Y C+
Sbjct: 161 CGRRFKEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMV 220
Query: 436 SGFMTPDKAGLSEPSQLYGKGELPMKEKEALGKLLSPISSMAHGVPEGDKHSLLGCLNLV 495
GF+ P+K L E +++ K K A G + S G+P + L NL
Sbjct: 221 CGFLFPNKESLIEHRKVHTK-------KTAFGTSSAQTDSPQGGMPSS-REDFLQLFNLR 272
Query: 496 PPLKSSCIERLQAAAKAAEMDPVNSYQAWQLMARGMAMEHGFLSKEHPLQRNHEDTLANA 555
P KS + ++DP ++QAWQL +G
Sbjct: 273 P--KSHPETGKKPVRCIPQLDPFTTFQAWQLATKGK------------------------ 306
Query: 556 GVLFDKEKREYVLVGADGSKQKMPADLVHSTKVGSQRDLPSKLDPLESSRDFLSHGLNQT 615
V +E +E G+ + + T GS L + + + S HG +
Sbjct: 307 -VAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHS-----HGEAPS 360
Query: 616 LEYNLQGPGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSG 675
++ + + P + KEKPT C +CG+ FRTYHQ+V+HSRVHK+DR+ + + +D R+
Sbjct: 361 VDADPKLPSS-KEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGT 419
Query: 676 SDQESQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSS--DIGEEAGRSA 733
+ + P N + G GG ED P D ++ G+
Sbjct: 420 CSPDLAA------PLDENGAVDRGEGGS--------EDGSEDGLPEGIHLDKNDDGGKIK 465
Query: 734 GVQQPALLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSAS 793
+ ++ ++C YCGK FR++++L +HLR HTGEKPYKC C+YA Q S
Sbjct: 466 HL------------TSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTS 513
Query: 794 LKYHLERHHRERQNG-AGPLSGQPPNQDHKDEMSSKASLFIRPDILRGAFKGLPGIDFRG 852
L+YHLERHH+E+Q A + NQD +D + + S + L+ F G D G
Sbjct: 514 LRYHLERHHKEKQTDVAAEVKNDGKNQDTEDALLTADS--AQTKNLKRFFDGAK--DVTG 569
Query: 853 GPASQQWTSGVLSSGDHSGQATGMSSEVPSDALKGTDLPSKSTHFSEIGRAYQSIVSNGV 912
P ++Q S + S V S A K T + H + + + N
Sbjct: 570 SPPAKQLKE------MPSVFQNVLGSAVLSPAHKDT----QDFHKNAADDSADKVNKNPT 619
Query: 913 NFQGSLQAFMDSFVLSSLKKEKDMKDKALADPP--SMKVHGVDGGEEKPSGKSS----QR 966
L + + + KA PP H ++ ++ +++ R
Sbjct: 620 --PAYLDLLKKRSAVETQANNLICRTKADVTPPPDGSTTHNLEVSPKEKQTETAADCRYR 677
Query: 967 KSEKSQYEPLDLSVRPDAASLPGSSVTVQDSIAWHGCLFCAFTTSSMELMALHLQANHLG 1026
S +PL+LSV + P S++ + I C FC F T E++ +H + H
Sbjct: 678 PSVDCHEKPLNLSVGA-LHNCPAISLS-KSLIPSITCPFCTFKTFYPEVLMMHQRLEH-- 733
Query: 1027 KAKRKDNTIGVTVNCKDQAREASKMALLPSLQSNKDL 1063
K N V NC++++ S+ P KD+
Sbjct: 734 ----KYNP-DVHKNCRNKSLLRSRRTGCPPALLGKDV 765
Score = 70.5 bits (171), Expect = 1e-11
Identities = 28/49 (57%), Positives = 37/49 (75%)
Query: 132 CPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
C CGK FR N L++H+RTHTGEKP+KC +C++ AAQK +L+ HL H
Sbjct: 473 CSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERH 521
Score = 47.0 bits (110), Expect = 1e-04
Identities = 20/55 (36%), Positives = 29/55 (52%)
Query: 126 KNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
K ++ C +CG+ FR + +HMRTH + C C R + LK H+RTH
Sbjct: 124 KENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
Score = 33.9 bits (76), Expect = 1.0
Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 3/40 (7%)
Query: 119 DIEDDARKNRK---YPCPLCGKRFRFNSILSLHMRTHTGE 155
D+E R ++ Y C +CG+RF+ L HMRTH G+
Sbjct: 142 DVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGK 181
>gi|156416026 zinc finger protein 219 [Homo sapiens]
Length = 722
Score = 242 bits (618), Expect = 1e-63
Identities = 228/778 (29%), Positives = 316/778 (40%), Gaps = 179/778 (23%)
Query: 95 SLNGRVDLQQFLNGQNLGI----MSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMR 150
+ +G +DLQ++ NG + M +S E A + R++PCP+CGKRFRFNSIL+LH+R
Sbjct: 19 AFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGE-RRFPCPVCGKRFRFNSILALHLR 77
Query: 151 THTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGKGRGRVREENRLLHELEERAILRD 210
H G + F+CP+C HRAAQ+ L+ HLRTH+ R R RLL ELEERA+LR+
Sbjct: 78 AHPGAQAFQCPHCGHRAAQRALLRSHLRTHQ-----PERPR-SPAARLLLELEERALLRE 131
Query: 211 KQLKGSLLQPRPDLKPPPHAQQAPLAACTLALQANHSVPDVAHPVPSPKPASVQEDAVAP 270
+L A + +QA + +A P P+S
Sbjct: 132 ARLGR--------------------ARSSGGMQATPATEGLARP---QAPSS-------- 160
Query: 271 AAGFRCTFCKGKFKKREELDRHIRILHKPYKCTLCDFAASQEEELISHVEKAHITAE--- 327
+ FRC +CKGKF+ E +RH+ ILH+P+KC LC F +SQEEEL+ H AH E
Sbjct: 161 -SAFRCPYCKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPL 219
Query: 328 ----------------------SAQGQGPNGGGEQSAN---------------EFRCEVC 350
S P E+ A EFRC+VC
Sbjct: 220 AATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVC 279
Query: 351 GQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKN-----KS 405
GQ F+Q+WFLKGHMRKHK SF+H C +CGR FKEPWFLKNHMKVH +KL
Sbjct: 280 GQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASG 339
Query: 406 PSDPEVPVPMGGMSQEAHANLYSRYLSCLQSGFMTPDKAGLSEPSQLYGKGELPMKEKEA 465
P+ P +G ++ E L P A EP L G L E
Sbjct: 340 PARAPQPPDLGLLAYEP--------LGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRP 391
Query: 466 LGKLLSPISSMAHGVPEGDKHSLLGCLNLVPPLKSSCIERLQAAAKAAEMDPVNSYQAWQ 525
G+ G G S G L L + R +A E + V + + +
Sbjct: 392 NGE----------GAEPGPGRSFGGFRPLSSALPARA-RRHRAEEPEEEEEVVEAEE--E 438
Query: 526 LMARGMAMEHGFLSKEHPLQ---RNHEDTLANAGVLFDKEKREYVLVGADGSKQKMPADL 582
ARG ++ G L+ HP H + A A + E L L
Sbjct: 439 TWARGRSL--GSLASLHPRPGEGPGHSASAAGAQARSTATQEENGL-------------L 483
Query: 583 VHSTKVGSQRDLPSKLDPLESSRDFLSHGLNQTLEYNLQGPGNMKEKPTECPDCGRVFRT 642
V T+ R K P +H L L + E+P +CP C
Sbjct: 484 VGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRV------HTGERPYKCPHCDYAGTQ 537
Query: 643 YHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRSTTPGSSNVTEESGVGG 702
+ H + H R ++R G+G PG G
Sbjct: 538 SGSLKYHLQRHHR-------------EQRSGAG-------------PGPPPEPPPPSQRG 571
Query: 703 GLSQTGSAQEDSPHPSS---PSSSDIGEEAGRSAGVQQPALLRDRSLGSAMKDCPYCGKT 759
Q+G+ + SP P++ +SS +G G ++ R+L +
Sbjct: 572 SAPQSGA--KPSPQPATWVEGASSPRPPSSGAGPGSRRKPASPGRTLRNGRGG------- 622
Query: 760 FRTSHHLKVHLRIHTGEKP------YKCPHCDYAGTQSASLKYHLERHHRERQNGAGP 811
+ L + LR G + ++C C +A + HL+ HH R G P
Sbjct: 623 --EAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRP 678
Score = 134 bits (336), Expect = 7e-31
Identities = 67/136 (49%), Positives = 86/136 (63%), Gaps = 10/136 (7%)
Query: 708 GSAQEDSPHPSSP---SSSDIGEEAGRSAGVQQPALL-----RDRSLGSAMKDCPYCGKT 759
GS P P S+S G +A +A ++ LL + G+ KDCP+CGK+
Sbjct: 447 GSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKS 506
Query: 760 FRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQNGAGPLSGQPPNQ 819
FR++HHLKVHLR+HTGE+PYKCPHCDYAGTQS SLKYHL+RHHRE+++GAGP G PP
Sbjct: 507 FRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGP--GPPPEP 564
Query: 820 DHKDEMSSKASLFIRP 835
+ S +P
Sbjct: 565 PPPSQRGSAPQSGAKP 580
Score = 52.4 bits (124), Expect = 3e-06
Identities = 31/79 (39%), Positives = 42/79 (53%), Gaps = 11/79 (13%)
Query: 954 GGEEKPSGKS-SQRKSEKSQYEPLDLSVR--PDAASLPGSSVTVQDSIAWHGCLFCAFTT 1010
G KP+ + R + EPLDLS+R P + PG ++ H CLFC F T
Sbjct: 604 GSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGAL--------HRCLFCPFAT 655
Query: 1011 SSMELMALHLQANHLGKAK 1029
+ ELMALHLQ +H +A+
Sbjct: 656 GAPELMALHLQVHHSRRAR 674
Score = 50.1 bits (118), Expect = 1e-05
Identities = 45/193 (23%), Positives = 73/193 (37%), Gaps = 18/193 (9%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
E+ CP CG+ FR + +H R H + + +R S + R
Sbjct: 54 ERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPR 113
Query: 688 TPGSSNVTE-ESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSL 746
+P + + E E ++ G A+ ++P++ L R ++
Sbjct: 114 SPAARLLLELEERALLREARLGRARSSGGMQATPATE---------------GLARPQAP 158
Query: 747 GSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQ 806
S+ CPYC FRTS + HL H +P+KC C + +Q L +H H +
Sbjct: 159 SSSAFRCPYCKGKFRTSAERERHL--HILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPE 216
Query: 807 NGAGPLSGQPPNQ 819
S PP Q
Sbjct: 217 RPLAATSAAPPPQ 229
Score = 41.2 bits (95), Expect = 0.007
Identities = 51/202 (25%), Positives = 70/202 (34%), Gaps = 34/202 (16%)
Query: 633 CPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRSTTPGSS 692
CP C FRT + H + R K GL GS QE + + S
Sbjct: 165 CPYCKGKFRTSAERERHLHILHRPWK-------CGLCS---FGSSQEEELLHHS------ 208
Query: 693 NVTEESGVGGGLSQTGSAQEDSPHP---------SSPSSSDIGEEAGRSAGVQQPALLRD 743
+T L+ T +A P P S P E + PA +
Sbjct: 209 -LTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEE 267
Query: 744 RSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHR 803
+ C CG++F S LK H+R H + CP C + LK H++ H
Sbjct: 268 PPAPPEFR-CQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHAS 326
Query: 804 E--RQNGAGPLSG-----QPPN 818
+ GP SG QPP+
Sbjct: 327 KLGPLRAPGPASGPARAPQPPD 348
>gi|156415998 zinc finger protein 219 [Homo sapiens]
Length = 722
Score = 242 bits (618), Expect = 1e-63
Identities = 228/778 (29%), Positives = 316/778 (40%), Gaps = 179/778 (23%)
Query: 95 SLNGRVDLQQFLNGQNLGI----MSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMR 150
+ +G +DLQ++ NG + M +S E A + R++PCP+CGKRFRFNSIL+LH+R
Sbjct: 19 AFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGE-RRFPCPVCGKRFRFNSILALHLR 77
Query: 151 THTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGKGRGRVREENRLLHELEERAILRD 210
H G + F+CP+C HRAAQ+ L+ HLRTH+ R R RLL ELEERA+LR+
Sbjct: 78 AHPGAQAFQCPHCGHRAAQRALLRSHLRTHQ-----PERPR-SPAARLLLELEERALLRE 131
Query: 211 KQLKGSLLQPRPDLKPPPHAQQAPLAACTLALQANHSVPDVAHPVPSPKPASVQEDAVAP 270
+L A + +QA + +A P P+S
Sbjct: 132 ARLGR--------------------ARSSGGMQATPATEGLARP---QAPSS-------- 160
Query: 271 AAGFRCTFCKGKFKKREELDRHIRILHKPYKCTLCDFAASQEEELISHVEKAHITAE--- 327
+ FRC +CKGKF+ E +RH+ ILH+P+KC LC F +SQEEEL+ H AH E
Sbjct: 161 -SAFRCPYCKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPL 219
Query: 328 ----------------------SAQGQGPNGGGEQSAN---------------EFRCEVC 350
S P E+ A EFRC+VC
Sbjct: 220 AATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVC 279
Query: 351 GQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKN-----KS 405
GQ F+Q+WFLKGHMRKHK SF+H C +CGR FKEPWFLKNHMKVH +KL
Sbjct: 280 GQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASG 339
Query: 406 PSDPEVPVPMGGMSQEAHANLYSRYLSCLQSGFMTPDKAGLSEPSQLYGKGELPMKEKEA 465
P+ P +G ++ E L P A EP L G L E
Sbjct: 340 PARAPQPPDLGLLAYEP--------LGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRP 391
Query: 466 LGKLLSPISSMAHGVPEGDKHSLLGCLNLVPPLKSSCIERLQAAAKAAEMDPVNSYQAWQ 525
G+ G G S G L L + R +A E + V + + +
Sbjct: 392 NGE----------GAEPGPGRSFGGFRPLSSALPARA-RRHRAEEPEEEEEVVEAEE--E 438
Query: 526 LMARGMAMEHGFLSKEHPLQ---RNHEDTLANAGVLFDKEKREYVLVGADGSKQKMPADL 582
ARG ++ G L+ HP H + A A + E L L
Sbjct: 439 TWARGRSL--GSLASLHPRPGEGPGHSASAAGAQARSTATQEENGL-------------L 483
Query: 583 VHSTKVGSQRDLPSKLDPLESSRDFLSHGLNQTLEYNLQGPGNMKEKPTECPDCGRVFRT 642
V T+ R K P +H L L + E+P +CP C
Sbjct: 484 VGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRV------HTGERPYKCPHCDYAGTQ 537
Query: 643 YHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRSTTPGSSNVTEESGVGG 702
+ H + H R ++R G+G PG G
Sbjct: 538 SGSLKYHLQRHHR-------------EQRSGAG-------------PGPPPEPPPPSQRG 571
Query: 703 GLSQTGSAQEDSPHPSS---PSSSDIGEEAGRSAGVQQPALLRDRSLGSAMKDCPYCGKT 759
Q+G+ + SP P++ +SS +G G ++ R+L +
Sbjct: 572 SAPQSGA--KPSPQPATWVEGASSPRPPSSGAGPGSRRKPASPGRTLRNGRGG------- 622
Query: 760 FRTSHHLKVHLRIHTGEKP------YKCPHCDYAGTQSASLKYHLERHHRERQNGAGP 811
+ L + LR G + ++C C +A + HL+ HH R G P
Sbjct: 623 --EAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRP 678
Score = 134 bits (336), Expect = 7e-31
Identities = 67/136 (49%), Positives = 86/136 (63%), Gaps = 10/136 (7%)
Query: 708 GSAQEDSPHPSSP---SSSDIGEEAGRSAGVQQPALL-----RDRSLGSAMKDCPYCGKT 759
GS P P S+S G +A +A ++ LL + G+ KDCP+CGK+
Sbjct: 447 GSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKS 506
Query: 760 FRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQNGAGPLSGQPPNQ 819
FR++HHLKVHLR+HTGE+PYKCPHCDYAGTQS SLKYHL+RHHRE+++GAGP G PP
Sbjct: 507 FRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGP--GPPPEP 564
Query: 820 DHKDEMSSKASLFIRP 835
+ S +P
Sbjct: 565 PPPSQRGSAPQSGAKP 580
Score = 52.4 bits (124), Expect = 3e-06
Identities = 31/79 (39%), Positives = 42/79 (53%), Gaps = 11/79 (13%)
Query: 954 GGEEKPSGKS-SQRKSEKSQYEPLDLSVR--PDAASLPGSSVTVQDSIAWHGCLFCAFTT 1010
G KP+ + R + EPLDLS+R P + PG ++ H CLFC F T
Sbjct: 604 GSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGAL--------HRCLFCPFAT 655
Query: 1011 SSMELMALHLQANHLGKAK 1029
+ ELMALHLQ +H +A+
Sbjct: 656 GAPELMALHLQVHHSRRAR 674
Score = 50.1 bits (118), Expect = 1e-05
Identities = 45/193 (23%), Positives = 73/193 (37%), Gaps = 18/193 (9%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
E+ CP CG+ FR + +H R H + + +R S + R
Sbjct: 54 ERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPR 113
Query: 688 TPGSSNVTE-ESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSL 746
+P + + E E ++ G A+ ++P++ L R ++
Sbjct: 114 SPAARLLLELEERALLREARLGRARSSGGMQATPATE---------------GLARPQAP 158
Query: 747 GSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQ 806
S+ CPYC FRTS + HL H +P+KC C + +Q L +H H +
Sbjct: 159 SSSAFRCPYCKGKFRTSAERERHL--HILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPE 216
Query: 807 NGAGPLSGQPPNQ 819
S PP Q
Sbjct: 217 RPLAATSAAPPPQ 229
Score = 41.2 bits (95), Expect = 0.007
Identities = 51/202 (25%), Positives = 70/202 (34%), Gaps = 34/202 (16%)
Query: 633 CPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRSTTPGSS 692
CP C FRT + H + R K GL GS QE + + S
Sbjct: 165 CPYCKGKFRTSAERERHLHILHRPWK-------CGLCS---FGSSQEEELLHHS------ 208
Query: 693 NVTEESGVGGGLSQTGSAQEDSPHP---------SSPSSSDIGEEAGRSAGVQQPALLRD 743
+T L+ T +A P P S P E + PA +
Sbjct: 209 -LTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEE 267
Query: 744 RSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHR 803
+ C CG++F S LK H+R H + CP C + LK H++ H
Sbjct: 268 PPAPPEFR-CQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHAS 326
Query: 804 E--RQNGAGPLSG-----QPPN 818
+ GP SG QPP+
Sbjct: 327 KLGPLRAPGPASGPARAPQPPD 348
>gi|156415996 zinc finger protein 219 [Homo sapiens]
Length = 722
Score = 242 bits (618), Expect = 1e-63
Identities = 228/778 (29%), Positives = 316/778 (40%), Gaps = 179/778 (23%)
Query: 95 SLNGRVDLQQFLNGQNLGI----MSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMR 150
+ +G +DLQ++ NG + M +S E A + R++PCP+CGKRFRFNSIL+LH+R
Sbjct: 19 AFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGE-RRFPCPVCGKRFRFNSILALHLR 77
Query: 151 THTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGKGRGRVREENRLLHELEERAILRD 210
H G + F+CP+C HRAAQ+ L+ HLRTH+ R R RLL ELEERA+LR+
Sbjct: 78 AHPGAQAFQCPHCGHRAAQRALLRSHLRTHQ-----PERPR-SPAARLLLELEERALLRE 131
Query: 211 KQLKGSLLQPRPDLKPPPHAQQAPLAACTLALQANHSVPDVAHPVPSPKPASVQEDAVAP 270
+L A + +QA + +A P P+S
Sbjct: 132 ARLGR--------------------ARSSGGMQATPATEGLARP---QAPSS-------- 160
Query: 271 AAGFRCTFCKGKFKKREELDRHIRILHKPYKCTLCDFAASQEEELISHVEKAHITAE--- 327
+ FRC +CKGKF+ E +RH+ ILH+P+KC LC F +SQEEEL+ H AH E
Sbjct: 161 -SAFRCPYCKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPL 219
Query: 328 ----------------------SAQGQGPNGGGEQSAN---------------EFRCEVC 350
S P E+ A EFRC+VC
Sbjct: 220 AATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVC 279
Query: 351 GQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKN-----KS 405
GQ F+Q+WFLKGHMRKHK SF+H C +CGR FKEPWFLKNHMKVH +KL
Sbjct: 280 GQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASG 339
Query: 406 PSDPEVPVPMGGMSQEAHANLYSRYLSCLQSGFMTPDKAGLSEPSQLYGKGELPMKEKEA 465
P+ P +G ++ E L P A EP L G L E
Sbjct: 340 PARAPQPPDLGLLAYEP--------LGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRP 391
Query: 466 LGKLLSPISSMAHGVPEGDKHSLLGCLNLVPPLKSSCIERLQAAAKAAEMDPVNSYQAWQ 525
G+ G G S G L L + R +A E + V + + +
Sbjct: 392 NGE----------GAEPGPGRSFGGFRPLSSALPARA-RRHRAEEPEEEEEVVEAEE--E 438
Query: 526 LMARGMAMEHGFLSKEHPLQ---RNHEDTLANAGVLFDKEKREYVLVGADGSKQKMPADL 582
ARG ++ G L+ HP H + A A + E L L
Sbjct: 439 TWARGRSL--GSLASLHPRPGEGPGHSASAAGAQARSTATQEENGL-------------L 483
Query: 583 VHSTKVGSQRDLPSKLDPLESSRDFLSHGLNQTLEYNLQGPGNMKEKPTECPDCGRVFRT 642
V T+ R K P +H L L + E+P +CP C
Sbjct: 484 VGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRV------HTGERPYKCPHCDYAGTQ 537
Query: 643 YHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRSTTPGSSNVTEESGVGG 702
+ H + H R ++R G+G PG G
Sbjct: 538 SGSLKYHLQRHHR-------------EQRSGAG-------------PGPPPEPPPPSQRG 571
Query: 703 GLSQTGSAQEDSPHPSS---PSSSDIGEEAGRSAGVQQPALLRDRSLGSAMKDCPYCGKT 759
Q+G+ + SP P++ +SS +G G ++ R+L +
Sbjct: 572 SAPQSGA--KPSPQPATWVEGASSPRPPSSGAGPGSRRKPASPGRTLRNGRGG------- 622
Query: 760 FRTSHHLKVHLRIHTGEKP------YKCPHCDYAGTQSASLKYHLERHHRERQNGAGP 811
+ L + LR G + ++C C +A + HL+ HH R G P
Sbjct: 623 --EAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRP 678
Score = 134 bits (336), Expect = 7e-31
Identities = 67/136 (49%), Positives = 86/136 (63%), Gaps = 10/136 (7%)
Query: 708 GSAQEDSPHPSSP---SSSDIGEEAGRSAGVQQPALL-----RDRSLGSAMKDCPYCGKT 759
GS P P S+S G +A +A ++ LL + G+ KDCP+CGK+
Sbjct: 447 GSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKS 506
Query: 760 FRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQNGAGPLSGQPPNQ 819
FR++HHLKVHLR+HTGE+PYKCPHCDYAGTQS SLKYHL+RHHRE+++GAGP G PP
Sbjct: 507 FRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGP--GPPPEP 564
Query: 820 DHKDEMSSKASLFIRP 835
+ S +P
Sbjct: 565 PPPSQRGSAPQSGAKP 580
Score = 52.4 bits (124), Expect = 3e-06
Identities = 31/79 (39%), Positives = 42/79 (53%), Gaps = 11/79 (13%)
Query: 954 GGEEKPSGKS-SQRKSEKSQYEPLDLSVR--PDAASLPGSSVTVQDSIAWHGCLFCAFTT 1010
G KP+ + R + EPLDLS+R P + PG ++ H CLFC F T
Sbjct: 604 GSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGAL--------HRCLFCPFAT 655
Query: 1011 SSMELMALHLQANHLGKAK 1029
+ ELMALHLQ +H +A+
Sbjct: 656 GAPELMALHLQVHHSRRAR 674
Score = 50.1 bits (118), Expect = 1e-05
Identities = 45/193 (23%), Positives = 73/193 (37%), Gaps = 18/193 (9%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
E+ CP CG+ FR + +H R H + + +R S + R
Sbjct: 54 ERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPR 113
Query: 688 TPGSSNVTE-ESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSL 746
+P + + E E ++ G A+ ++P++ L R ++
Sbjct: 114 SPAARLLLELEERALLREARLGRARSSGGMQATPATE---------------GLARPQAP 158
Query: 747 GSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQ 806
S+ CPYC FRTS + HL H +P+KC C + +Q L +H H +
Sbjct: 159 SSSAFRCPYCKGKFRTSAERERHL--HILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPE 216
Query: 807 NGAGPLSGQPPNQ 819
S PP Q
Sbjct: 217 RPLAATSAAPPPQ 229
Score = 41.2 bits (95), Expect = 0.007
Identities = 51/202 (25%), Positives = 70/202 (34%), Gaps = 34/202 (16%)
Query: 633 CPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRSTTPGSS 692
CP C FRT + H + R K GL GS QE + + S
Sbjct: 165 CPYCKGKFRTSAERERHLHILHRPWK-------CGLCS---FGSSQEEELLHHS------ 208
Query: 693 NVTEESGVGGGLSQTGSAQEDSPHP---------SSPSSSDIGEEAGRSAGVQQPALLRD 743
+T L+ T +A P P S P E + PA +
Sbjct: 209 -LTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEE 267
Query: 744 RSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHR 803
+ C CG++F S LK H+R H + CP C + LK H++ H
Sbjct: 268 PPAPPEFR-CQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHAS 326
Query: 804 E--RQNGAGPLSG-----QPPN 818
+ GP SG QPP+
Sbjct: 327 KLGPLRAPGPASGPARAPQPPD 348
>gi|138175817 zinc finger protein 236 [Homo sapiens]
Length = 1845
Score = 115 bits (287), Expect = 4e-25
Identities = 186/803 (23%), Positives = 286/803 (35%), Gaps = 172/803 (21%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGK 187
+ + C +C F N L+ HM TH KP+KCP+C+ + K H++ H+
Sbjct: 1021 KAFSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAV 1080
Query: 188 GRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTLALQANHS 247
E + E EE R+ K RP++ + A LA A S
Sbjct: 1081 SATGETEGGDICMEEEEEHSDRNASRKS-----RPEVITFTEEETAQLAKIRPQESATVS 1135
Query: 248 VPDVAHPVPSPKPASVQEDAVA-----PAAGFRCTFCKGKFKKREELDRHIRIL--HKPY 300
+ S D A P CT+C FKK +L RH+RI KPY
Sbjct: 1136 EKVLVQSAAEKDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPY 1195
Query: 301 KCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFL 360
KC C + + + L HV K H GQ F C VC FS L
Sbjct: 1196 KCDECGKSFTVKSTLDCHV-KTH------TGQ----------KLFSCHVCSNAFSTKGSL 1238
Query: 361 KGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKNKSPSDPEVPVPMGGMSQ 420
K HMR H + C C RF+ K HM+ H P + PM S
Sbjct: 1239 KVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHY--------KPDPKKARKPMTRSSS 1290
Query: 421 EAHANLYSRYLSCLQSGFMTPDKAGLSEPSQLYGKGELPMKEKEALGKLLSPISSMAHG- 479
E + ++ L S P+ + S L G+ + + + +G+ + P S A G
Sbjct: 1291 EG-----LQPVNLLNSSSTDPN-VFIMNNSVLTGQFDQNLLQPGLVGQAILPASVSAGGD 1344
Query: 480 ----VPEGDKHSLLG-----CLNLV-PPLKSSCIERLQAAAKAAEMDP---VNSYQAWQL 526
+ +G +L G NLV P ++ S I+ ++DP + Q L
Sbjct: 1345 LTVSLTDGSLATLEGIQLQLAANLVGPNVQISGIDAASINNITLQIDPSILQQTLQQGNL 1404
Query: 527 MARGMAMEHGFLSKEHPLQRNHEDTLAN------AGVLFDKEKREYVLVGADGSKQKMPA 580
+A+ + E G + LQ + A+ +G+ L S+Q
Sbjct: 1405 LAQQLTGEPGLAPQNSSLQTSDSTVPASVVIQPISGLSLQPTVTSANLTIGPLSEQ---- 1460
Query: 581 DLVHSTKVGSQRDLPSKL----------DPLESSRDFLSHGLNQTLEYNLQGP------G 624
D V +T +DL + P E + + L+Q L GP G
Sbjct: 1461 DSVLTTNSSGTQDLTQVMTSQGLVSPSGGPHEITLTINNSSLSQVLA-QAAGPTATSSSG 1519
Query: 625 NMKE--------------KPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDE 670
+ +E P+ P T + V+ S V G + + + L +
Sbjct: 1520 SPQEITLTISELNTTSGSLPSTTPMSPSAISTQNLVMSSSGV------GGDASVTLTLAD 1573
Query: 671 RRG---SGSDQESQSVSRSTTPGSSNVTEE--SGVGGGLSQTGSAQEDSPHPSSPSSSDI 725
+G G D + +++ + +T+ SG GG S +P +S + +I
Sbjct: 1574 TQGMLSGGLDTVTLNITSQGQQFPALLTDPSLSGQGGAGSPQVILVSHTPQSASAACEEI 1633
Query: 726 GEE----AGRSAGVQQP--------ALLRDRSLGSA---------------MKDCPYCGK 758
+ +G A QP L DR+ SA + CP C K
Sbjct: 1634 AYQVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRK 1693
Query: 759 TFRTSHHLKVHL------------------------------------RIHTGEKPYKCP 782
F+ + HLK H+ RIHTGE+P+ C
Sbjct: 1694 AFKRATHLKEHMQTHQAGPSLSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCT 1753
Query: 783 HCDYAGTQSASLKYHLERHHRER 805
C+ A Q ++L+ H+++H ER
Sbjct: 1754 LCEKAFNQKSALQVHMKKHTGER 1776
Score = 99.0 bits (245), Expect = 3e-20
Identities = 157/738 (21%), Positives = 264/738 (35%), Gaps = 142/738 (19%)
Query: 120 IEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRT 179
+ D R ++ + C C + F L+LH TH+GE P CP C+ + ++ +LK H+
Sbjct: 56 MRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCPVCNKKFSRVASLKAHIML 114
Query: 180 HKLGNLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACT 239
H+ +EEN + E + L+ QL + + R +L +Q AC
Sbjct: 115 HE-----------KEENLICSECGDEFTLQ-SQLAVHMEEHRQEL---AGTRQHACKACK 159
Query: 240 LALQANHSVPD---VAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRIL 296
+ + + + + + S + + C C F+K +L RHIRI
Sbjct: 160 KEFETSSELKEHMKTHYKIRVSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIH 219
Query: 297 --HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVF 354
+P+KC+ C A +Q+ L +H+ K G+ P+ C C F
Sbjct: 220 TGERPFKCSECGKAFNQKGALQTHMIK-------HTGEKPHA----------CAFCPAAF 262
Query: 355 SQAWFLKGHMRK----HKDSFEHCCQICGRRFKEPWFLKNHM-KVHLNKLSVKNKSPSDP 409
SQ L+ H+++ K+ + C C FK L H+ K+H+ +N + S
Sbjct: 263 SQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMG--GPQNSTSSTE 320
Query: 410 EVPVPMGGMSQ-------EAHANLYSRYLSCLQSGFMTPDKAGLSEPSQLYGKGELPMKE 462
V + Q EA A S S + LSEP+ + G+ P
Sbjct: 321 TAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPV-ESGQSPQP- 378
Query: 463 KEALGKLLSPISSMAHGV-PEGDKHSLLGCLNLVPPLKSSCIERLQAAAKAAEMDPVNSY 521
G+ LS + + + ++S L + SC + +A A+ V+S
Sbjct: 379 ----GQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSC--HAKTSAPHAQNPDVSSV 432
Query: 522 QAWQLMARGMAMEHGFLSKEHPLQRNHEDTLANAGVLFDKEKRE-----YVLVGADGSKQ 576
Q E S E L + + + RE + + +
Sbjct: 433 SNEQTDPTDAEQEKEQESPE-KLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEF 491
Query: 577 KMPADLVHSTKVGSQRDLPSKLDPLESSRDFLSHGLNQTLEYNLQGPGNMKEKPTECPDC 636
+ P+DLV ++ + P + + F + + TL +++ + K +C C
Sbjct: 492 RKPSDLVRHIRIHTHE------KPFKCPQCFRAFAVKSTLTAHIKTHTGI--KAFKCQYC 543
Query: 637 GRVFRTYHQVVVHSRVH------------KRDRKGEEDGLHVGLDERRGSGSDQESQSVS 684
+ F T + VH R+H K+ R H+ + Q
Sbjct: 544 MKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKP 603
Query: 685 RSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDR 744
G +N+ P P P +Q+P L+ D
Sbjct: 604 AKVRVGKTNI--------------------PVPDIP--------------LQEPILITDL 629
Query: 745 SLGSAM-----------------KDCPY----CGKTFRTSHHLKVHLRIHTGEKPYKCPH 783
L + D PY C + ++ S HLK H+R HTGEKP+KC
Sbjct: 630 GLIQPIPKNQFFQSYFNNNFVNEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQ 689
Query: 784 CDYAGTQSASLKYHLERH 801
C + LK H+ H
Sbjct: 690 CGRGFVSAGVLKAHIRTH 707
Score = 75.5 bits (184), Expect = 3e-13
Identities = 76/294 (25%), Positives = 121/294 (41%), Gaps = 43/294 (14%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQNGA--- 809
CP+CGKTF+ L H+RIHTGE+P+KC C A Q +L+ H+ +H E+ +
Sbjct: 199 CPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHACAFC 258
Query: 810 -GPLSGQPPNQDHKDEMSS--KASLFIRPDILRGAFKGLPGID------FRGGP---ASQ 857
S + Q H + S K FK L ++ GGP S
Sbjct: 259 PAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSS 318
Query: 858 QWTSGVLSS--------GDHSGQATGMSSEVPSDALK---------GTDLPSKSTHFSEI 900
T+ VL++ QAT SS+ S A+ P +S +
Sbjct: 319 TETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQP 378
Query: 901 GRAYQSIVSNGVNFQGSLQAFMDSFVLSSLKKEKDMKDKALADPPSMKVHGVD---GGEE 957
G+ Q ++ G+N Q LQ +++ LSS+ D A + D E
Sbjct: 379 GQ--QLSITVGIN-QDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNE 435
Query: 958 KPSGKSSQRKSEKSQYEPLDLS----VRPDAASLPGSSVTVQDSIAWHGCLFCA 1007
+ ++++ E+ E LD ++ + LPG S+ ++ + WH C +CA
Sbjct: 436 QTDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPG-SIREENGVRWHVCPYCA 488
Score = 65.5 bits (158), Expect = 3e-10
Identities = 68/320 (21%), Positives = 114/320 (35%), Gaps = 65/320 (20%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGK 187
+ + C +C F L HM H +P+ CPYC N K H++TH+
Sbjct: 711 KSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRY----- 765
Query: 188 GRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAA--------CT 239
E + L + ++ A + D + +Q ++ + + P A
Sbjct: 766 ------ELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAM 819
Query: 240 LALQANHSVPDVAHPVP---SPKPASVQEDA-VAPAAGFRCTFCKGKFKKREELDRHIRI 295
L L+ H V + + +P ED VAP R +F+++ +
Sbjct: 820 LDLEPQHVVGTEEAGLGQQLADQPLEADEDGFVAPQDPLRGHV--DQFEEQSPAQQSFEP 877
Query: 296 LHKPYKCTLCD-------FAASQEEELISHVEKAHITAESAQG---QGPNGGG------- 338
P T+ D F Q+ + S +E ++ Q Q P+ G
Sbjct: 878 AGLPQGFTVTDTYHQQPQFPPVQQLQDSSTLESQALSTSFHQQSLLQAPSSDGMNVTTRL 937
Query: 339 -----------------------EQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCC 375
+QS +RC+ C + F ++ LK H+R H + C
Sbjct: 938 IQESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKC 997
Query: 376 QICGRRFKEPWFLKNHMKVH 395
++CGR F LK+H K H
Sbjct: 998 KLCGRGFVSSGVLKSHEKTH 1017
Score = 63.9 bits (154), Expect = 9e-10
Identities = 118/552 (21%), Positives = 179/552 (32%), Gaps = 96/552 (17%)
Query: 274 FRCTFCKGKFKKREELDRHIRILH---KPYKCTLCD----FAASQEEELISHVEKAHITA 326
F+C +C F L HIR LH +P+ C CD + ++ + SH + +
Sbjct: 538 FKCQYCMKSFSTSGSLKVHIR-LHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELRK 596
Query: 327 ESAQGQGPN---GGGEQSANEFRCE-------------VCGQVFSQAWFLKGHMRKHKDS 370
Q + G + + + F Q++F + +
Sbjct: 597 MRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNEADRP 656
Query: 371 FEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKNKSPSDPEVPVPMGGMSQEAHANLYSRY 430
++ C C R +K+ LK H++ H + K V + H L S
Sbjct: 657 YK--CFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFK 714
Query: 431 LSCLQSGFMTPDKAGLSEPSQLYGKGELPMKEKEALGKLLSPISSMAHGVPEGDKHSLLG 490
F T G M L + P + L
Sbjct: 715 CLICNGAFTTG------------GSLRRHMGIHNDLRPYMCPYCQKTF-------KTSLN 755
Query: 491 CLNLVPPLKSSCIERLQAAAKAAEMDPVNSYQAWQLMARGMAMEHGFLSKEHPLQRNHED 550
C + + ++LQ +AA +D Q Q M M+ S E P + E
Sbjct: 756 CKKHMKTHRYELAQQLQQHQQAASIDDSTVDQ--QSMQASTQMQVEIESDELP--QTAEV 811
Query: 551 TLANAGVLFDKEKREYVLVGADGSKQKMPADLVHSTKVGSQRDLPSKLDPLESSRDFLSH 610
AN + D E + V G Q++ + + + G + DPL D
Sbjct: 812 VAANPEAMLDLEPQHVVGTEEAGLGQQLADQPLEADEDG----FVAPQDPLRGHVD---- 863
Query: 611 GLNQTLEYNLQGPGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDE 670
++ Q P +P P V TYHQ V + E
Sbjct: 864 ------QFEEQSPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQQLQDSSTL--------E 909
Query: 671 RRGSGSDQESQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQE-DSPHPSSPSSSDIGEEA 729
+ + QS+ ++ + NVT L Q S +E D S D +++
Sbjct: 910 SQALSTSFHQQSLLQAPSSDGMNVTTR------LIQESSQEELDLQAQGSQFLEDNEDQS 963
Query: 730 GRSAGVQQPALLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGT 789
RS C YC K F+ S HLK H+R HTGEKPYKC C
Sbjct: 964 RRSYR------------------CDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFV 1005
Query: 790 QSASLKYHLERH 801
S LK H + H
Sbjct: 1006 SSGVLKSHEKTH 1017
Score = 62.4 bits (150), Expect = 3e-09
Identities = 35/83 (42%), Positives = 47/83 (56%), Gaps = 7/83 (8%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHL-RTHK-LGNL 185
R + C LC K F S L +HM+ HTGE+P+KC YC QK N+K+H+ R H G L
Sbjct: 1748 RPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGAL 1807
Query: 186 GKGRGRVREE----NRLLHELEE 204
+ G ++ +R LH LEE
Sbjct: 1808 QESAGHPEQDGEELSRTLH-LEE 1829
Score = 62.0 bits (149), Expect = 4e-09
Identities = 25/54 (46%), Positives = 33/54 (61%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQ 806
C YC K+F TS LKVH+R+HTG +P+ CPHCD S K H+ H + +
Sbjct: 540 CQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTE 593
Score = 61.2 bits (147), Expect = 6e-09
Identities = 29/64 (45%), Positives = 37/64 (57%), Gaps = 2/64 (3%)
Query: 117 MSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIH 176
+ D ED +R R Y C C K F+ +S L H+R+HTGEKP+KC C G LK H
Sbjct: 956 LEDNEDQSR--RSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSH 1013
Query: 177 LRTH 180
+TH
Sbjct: 1014 EKTH 1017
Score = 60.1 bits (144), Expect = 1e-08
Identities = 39/124 (31%), Positives = 48/124 (38%), Gaps = 19/124 (15%)
Query: 274 FRCTFCKGKFKKREELDRHIR--ILHKPYKCTLCDFAASQEEELISHVEKAHITAESAQG 331
+RC +C FKK L +H+R KPYKC LC L SH EK H ++
Sbjct: 967 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSH-EKTHTGVKA--- 1022
Query: 332 QGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNH 391
F C VC F+ L HM H + C C F+ K H
Sbjct: 1023 -------------FSCSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKH 1069
Query: 392 MKVH 395
MK H
Sbjct: 1070 MKRH 1073
Score = 59.7 bits (143), Expect = 2e-08
Identities = 56/207 (27%), Positives = 84/207 (40%), Gaps = 38/207 (18%)
Query: 623 PGNMKEKPT---ECPDCGRVFRTYHQVVVHSR-VHKRDRKGEEDGLHVGLDERRGSGSDQ 678
PGN EK +C +C R F + ++ HS+ VH R+R +H G
Sbjct: 1646 PGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRER------IH---------GCPV 1690
Query: 679 ESQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQP 738
++ R+T T ++G P SS + A +
Sbjct: 1691 CRKAFKRATHLKEHMQTHQAG---------------PSLSSQKPRVFKCDTCEKAFAKPS 1735
Query: 739 ALLRDRSL--GSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKY 796
L R + G C C K F L+VH++ HTGE+PYKC +C TQ +++K
Sbjct: 1736 QLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMKL 1795
Query: 797 HLERHHRERQNGAGPLSGQPPNQDHKD 823
H++R H GA S P QD ++
Sbjct: 1796 HMKRAH--SYAGALQESAGHPEQDGEE 1820
Score = 53.5 bits (127), Expect = 1e-06
Identities = 23/57 (40%), Positives = 32/57 (56%)
Query: 124 ARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
++K R + C C K F S L H R HTGE+PF C C+ QK L++H++ H
Sbjct: 1716 SQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKH 1772
Score = 51.2 bits (121), Expect = 6e-06
Identities = 25/69 (36%), Positives = 37/69 (53%), Gaps = 2/69 (2%)
Query: 114 MSQMSDIEDDARKNRKYP--CPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKG 171
+S++ D + + + K+ C C K F+ S L H+R HTGEKP+KC C K
Sbjct: 1149 ISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKS 1208
Query: 172 NLKIHLRTH 180
L H++TH
Sbjct: 1209 TLDCHVKTH 1217
Score = 49.7 bits (117), Expect = 2e-05
Identities = 55/248 (22%), Positives = 92/248 (37%), Gaps = 35/248 (14%)
Query: 206 AILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTLALQANHSVPDVA-HPVPSPKPASVQ 264
A+L D L G P + H Q+ AAC + + V V+ + P +P
Sbjct: 1598 ALLTDPSLSGQGGAGSPQVILVSHTPQSASAACE---EIAYQVAGVSGNLAPGNQPEK-- 1652
Query: 265 EDAVAPAAGFRCTFCKGKFKKREELDRHIRILH---KPYKCTLCDFAASQEEELISHVEK 321
+C C F L H + +H + + C +C A + L H++
Sbjct: 1653 -----EGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQ- 1706
Query: 322 AHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRR 381
H S Q P F+C+ C + F++ L+ H R H C +C +
Sbjct: 1707 THQAGPSLSSQKPR--------VFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKA 1758
Query: 382 FKEPWFLKNHMKVHLNKLSVKNKSPSDPEVPVPMGGMSQEAHANLYSR----YLSCLQSG 437
F + L+ HMK H + K + G +Q+++ L+ + Y LQ
Sbjct: 1759 FNQKSALQVHMKKHTGERPYK--------CAYCVMGFTQKSNMKLHMKRAHSYAGALQES 1810
Query: 438 FMTPDKAG 445
P++ G
Sbjct: 1811 AGHPEQDG 1818
Score = 47.4 bits (111), Expect = 9e-05
Identities = 20/53 (37%), Positives = 29/53 (54%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
+ + C CG+ F +L H+RTHTG K FKC C+ G+L+ H+ H
Sbjct: 683 KPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIH 735
Score = 47.0 bits (110), Expect = 1e-04
Identities = 21/50 (42%), Positives = 30/50 (60%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHH 802
C CG+ F ++ LK H+R HTG K +KC C+ A T SL+ H+ H+
Sbjct: 687 CSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHN 736
Score = 46.6 bits (109), Expect = 2e-04
Identities = 117/605 (19%), Positives = 203/605 (33%), Gaps = 119/605 (19%)
Query: 276 CTFCKGKFKKREELDRHIRILH------KPYKCTLCDFAASQEEELISHVEKAHITAESA 329
C+ C +F + +L H+ + + C C EL H+ K H +
Sbjct: 123 CSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHM-KTHYKIRVS 181
Query: 330 QGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLK 389
+ N ++S + C CG+ F + L H+R H C CG+ F + K
Sbjct: 182 STRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQ----K 237
Query: 390 NHMKVHLNKLSVKNKSPSDPEVPVPMGGMSQEAHANLYSRYLSCLQSGFMTPDKAGLSEP 449
++ H+ +K+ SQ+ NL S ++ + S +E
Sbjct: 238 GALQTHM----IKHTGEKPHACAFCPAAFSQKG--NLQS-HVQRVHSEVKNGPTYNCTEC 290
Query: 450 SQLYGKGELPMKEKEALGKLLSPISSMAHGVPEGDK------HSLLGCLNLVPPLK---- 499
S ++ ++LG L + IS M G P+ H L L PL+
Sbjct: 291 SCVF----------KSLGSLNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEA 340
Query: 500 --------------SSCIERLQAAAKAAEMDPVNSYQAWQLMARGM---------AMEHG 536
S I++L ++ A ++ S Q Q ++ + A+E+
Sbjct: 341 QATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENS 400
Query: 537 FLSK----EHPLQRNHEDTLANAGVLFDKEKREYVLVGADGSKQKMPADLVHSTKVGSQR 592
LS HP H T A D V + ++Q P D ++
Sbjct: 401 GLSSIPAAAHPNDSCHAKTSAPHAQNPD--------VSSVSNEQTDPTDAEQE----KEQ 448
Query: 593 DLPSKLDPLESSR-----DFLSHGLNQT----------LEYNLQGPGNM--------KEK 629
+ P KLD E FL + + + P ++ EK
Sbjct: 449 ESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEK 508
Query: 630 PTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRSTTP 689
P +CP C R F + H + H + + + SGS + + P
Sbjct: 509 PFKCPQCFRAFAVKSTLTAHIKTHTGIKAFK---CQYCMKSFSTSGSLKVHIRLHTGVRP 565
Query: 690 GSSNVTEESGVGGGLSQTGSAQE-------DSPHPSSPSSSDIGEE--AGRSAGVQQPAL 740
+ ++ G +T A H P+ +G+ +Q+P L
Sbjct: 566 FACPHCDKKFRTSGHRKTHIASHFKHTELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPIL 625
Query: 741 LRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLER 800
+ D L + + F + ++ ++PYKC +C A +S LK H+
Sbjct: 626 ITDLGLIQPIPKNQFFQSYFNNNF-------VNEADRPYKCFYCHRAYKKSCHLKQHIRS 678
Query: 801 HHRER 805
H E+
Sbjct: 679 HTGEK 683
Score = 46.2 bits (108), Expect = 2e-04
Identities = 35/129 (27%), Positives = 50/129 (38%), Gaps = 21/129 (16%)
Query: 275 RCTFCKGKFKKREELDRHIRILH---KPYKCTLCDFAASQEEELISHVEKAHITAESAQG 331
+C C F K + RH+R KP++C C + E L H + H G
Sbjct: 38 KCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLH-KCTH------SG 90
Query: 332 QGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNH 391
+ P C VC + FS+ LK H+ H+ C CG F L H
Sbjct: 91 EDPT-----------CPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVH 139
Query: 392 MKVHLNKLS 400
M+ H +L+
Sbjct: 140 MEEHRQELA 148
Score = 45.1 bits (105), Expect = 5e-04
Identities = 53/262 (20%), Positives = 94/262 (35%), Gaps = 59/262 (22%)
Query: 109 QNLGIMSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMR-THTGEKPFKCPYCDHRA 167
Q G+ ++ ++ R + C C + F ++L H + H E+ CP C
Sbjct: 1636 QVAGVSGNLAPGNQPEKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAF 1695
Query: 168 AQKGNLKIHLRTHKLG-NLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKP 226
+ +LK H++TH+ G +L + RV + + E+A + QL +
Sbjct: 1696 KRATHLKEHMQTHQAGPSLSSQKPRVFKCDTC-----EKAFAKPSQL---------ERHS 1741
Query: 227 PPHAQQAPLAACTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKR 286
H + P CTL C+ F ++
Sbjct: 1742 RIHTGERPF-HCTL--------------------------------------CEKAFNQK 1762
Query: 287 EELDRHIR--ILHKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQG--PNGGGEQSA 342
L H++ +PYKC C +Q+ + H+++AH A + Q P GE+ +
Sbjct: 1763 SALQVHMKKHTGERPYKCAYCVMGFTQKSNMKLHMKRAHSYAGALQESAGHPEQDGEELS 1822
Query: 343 NEFRCEVCGQVFSQAWFLKGHM 364
E Q + W H+
Sbjct: 1823 RTLHLEEVVQEAAGEWQALTHV 1844
Score = 44.3 bits (103), Expect = 8e-04
Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 741 LRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLER 800
+RD C C +TF +L +H H+GE P CP C+ ++ ASLK H+
Sbjct: 56 MRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCPVCNKKFSRVASLKAHIML 114
Query: 801 HHRE 804
H +E
Sbjct: 115 HEKE 118
Score = 43.5 bits (101), Expect = 0.001
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 732 SAGVQQPALLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQS 791
SAGV + + L S C C F T L+ H+ IH +PY CP+C S
Sbjct: 696 SAGVLKAHIRTHTGLKSFK--CLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTS 753
Query: 792 ASLKYHLERHHRE 804
+ K H++ H E
Sbjct: 754 LNCKKHMKTHRYE 766
Score = 42.7 bits (99), Expect = 0.002
Identities = 24/100 (24%), Positives = 39/100 (39%), Gaps = 17/100 (17%)
Query: 298 KPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQA 357
+ Y+C C+ + L HV S G+ P ++C++CG+ F +
Sbjct: 965 RSYRCDYCNKGFKKSSHLKQHVR-------SHTGEKP----------YKCKLCGRGFVSS 1007
Query: 358 WFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLN 397
LK H + H C +C F L HM H++
Sbjct: 1008 GVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHMS 1047
Score = 41.6 bits (96), Expect = 0.005
Identities = 18/52 (34%), Positives = 24/52 (46%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRE 804
CP C K F LK H+ +H E+ C C T + L H+E H +E
Sbjct: 95 CPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQE 146
Score = 37.4 bits (85), Expect = 0.094
Identities = 29/121 (23%), Positives = 42/121 (34%), Gaps = 48/121 (39%)
Query: 108 GQNLGIMSQMSDIEDDARKN----RKYPCPLCGKRFRFNSILSLHMRT------------ 151
G + SQ++ ++ R+ R++ C C K F +S L HM+T
Sbjct: 127 GDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVSSTRSY 186
Query: 152 --------------------------------HTGEKPFKCPYCDHRAAQKGNLKIHLRT 179
HTGE+PFKC C QKG L+ H+
Sbjct: 187 NRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIK 246
Query: 180 H 180
H
Sbjct: 247 H 247
Score = 31.2 bits (69), Expect = 6.8
Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 10/75 (13%)
Query: 340 QSANEFRCEVCGQVFSQAWFLKGHMRKH-KDSFEHCCQICGRRFKEPWFLKNHMKVHLNK 398
Q N +CE+C F + + HMR H ++ H C C + F + L H H
Sbjct: 32 QVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTH--- 88
Query: 399 LSVKNKSPSDPEVPV 413
S DP PV
Sbjct: 89 ------SGEDPTCPV 97
>gi|32698786 zinc finger protein 227 [Homo sapiens]
Length = 799
Score = 100 bits (250), Expect = 7e-21
Identities = 81/288 (28%), Positives = 114/288 (39%), Gaps = 45/288 (15%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH------K 181
+ Y C CGK F ++ L +H RTHTGEKP+KC C +Q N + H R H K
Sbjct: 322 KSYRCDSCGKGFSSSTGLIIHYRTHTGEKPYKCEECGKCFSQSSNFQCHQRVHTEEKPYK 381
Query: 182 LGNLGKGRG---RVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAAC 238
GKG G +R R+ E+ ++ KG + H + P
Sbjct: 382 CEECGKGFGWSVNLRVHQRV--HRGEKPYKCEECGKGFTQAAHFHIHQRVHTGEKPYKCD 439
Query: 239 TLALQANHSVPDVAH--PVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRIL 296
+H+ P + H KP ++C C F + +L H R+
Sbjct: 440 VCGKGFSHNSPLICHRRVHTGEKP-------------YKCEACGKGFTRNTDLHIHFRVH 486
Query: 297 --HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVF 354
KPYKC C SQ L H + H GE+ F+CE CG+ F
Sbjct: 487 TGEKPYKCKECGKGFSQASNLQVH-QNVHT-------------GEK---RFKCETCGKGF 529
Query: 355 SQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVK 402
SQ+ L+ H R H + C +CG+ F LK H +H + K
Sbjct: 530 SQSSKLQTHQRVHTGEKPYRCDVCGKDFSYSSNLKLHQVIHTGEKPYK 577
Score = 97.1 bits (240), Expect = 1e-19
Identities = 80/307 (26%), Positives = 119/307 (38%), Gaps = 41/307 (13%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGK 187
+ Y C +CGK F NS L H R HTGEKP+KC C + +L IH R H K
Sbjct: 434 KPYKCDVCGKGFSHNSPLICHRRVHTGEKPYKCEACGKGFTRNTDLHIHFRVHTGEKPYK 493
Query: 188 ----GRGRVREENRLLHELEERAILRDKQ-------LKGSLLQPRPDLKPPPHAQQAPLA 236
G+G + N +H+ R K + S LQ + + +
Sbjct: 494 CKECGKGFSQASNLQVHQNVHTGEKRFKCETCGKGFSQSSKLQTHQRVHTGEKPYRCDVC 553
Query: 237 ACTLALQANHSVPDVAHPVPSPKPAS-------------VQEDAVAPAAGFRCTFCKGKF 283
+ +N + V H P + + ++C C F
Sbjct: 554 GKDFSYSSNLKLHQVIHTGEKPYKCEECGKGFSWRSNLHAHQRVHSGEKPYKCEQCDKSF 613
Query: 284 KKREELDRHIRIL--HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQS 341
+ + H R+ KPYKC +C SQ L SH ++ H T E G G +
Sbjct: 614 SQAIDFRVHQRVHTGEKPYKCGVCGKGFSQSSGLQSH-QRVH-TGEKPYKCDVCGKGFRY 671
Query: 342 ANEF-------------RCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFL 388
+++F +CE CG+ F ++ L+ H R H H C+ CG+ F P L
Sbjct: 672 SSQFIYHQRGHTGEKPYKCEECGKGFGRSLNLRHHQRVHTGEKPHICEECGKAFSLPSNL 731
Query: 389 KNHMKVH 395
+ H+ VH
Sbjct: 732 RVHLGVH 738
Score = 86.3 bits (212), Expect = 2e-16
Identities = 80/296 (27%), Positives = 111/296 (37%), Gaps = 41/296 (13%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH------K 181
+++ C CGK F +S L H R HTGEKP++C C + NLK+H H K
Sbjct: 518 KRFKCETCGKGFSQSSKLQTHQRVHTGEKPYRCDVCGKDFSYSSNLKLHQVIHTGEKPYK 577
Query: 182 LGNLGKG---RGRVREENRLLHELEERAILRDKQLKGSLLQPRP-DLKPPPHAQQAPL-- 235
GKG R + R+ H E+ + +Q S Q + H + P
Sbjct: 578 CEECGKGFSWRSNLHAHQRV-HSGEKP--YKCEQCDKSFSQAIDFRVHQRVHTGEKPYKC 634
Query: 236 AACTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIR- 294
C + + KP ++C C F+ + H R
Sbjct: 635 GVCGKGFSQSSGLQSHQRVHTGEKP-------------YKCDVCGKGFRYSSQFIYHQRG 681
Query: 295 -ILHKPYKCTLCDFAASQEEELISHV-----EKAHITAESAQGQG-PNG-----GGEQSA 342
KPYKC C + L H EK HI E + P+ G
Sbjct: 682 HTGEKPYKCEECGKGFGRSLNLRHHQRVHTGEKPHICEECGKAFSLPSNLRVHLGVHTRE 741
Query: 343 NEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNK 398
F+CE CG+ FSQ+ L+ H R H + C IC + F+ L H KVH K
Sbjct: 742 KLFKCEECGKGFSQSARLEAHQRVHTGEKPYKCDICDKDFRHRSRLTYHQKVHTGK 797
Score = 85.9 bits (211), Expect = 2e-16
Identities = 77/311 (24%), Positives = 120/311 (38%), Gaps = 34/311 (10%)
Query: 115 SQMSDIEDDAR---KNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKG 171
SQ S+ + R + + Y C CGK F ++ L +H R H GEKP+KC C Q
Sbjct: 362 SQSSNFQCHQRVHTEEKPYKCEECGKGFGWSVNLRVHQRVHRGEKPYKCEECGKGFTQAA 421
Query: 172 NLKIHLRTHKLGNLGK----GRGRVREENRLLHE---LEERAILRDKQLKGSLLQPRPDL 224
+ IH R H K G+G + H E+ + KG +
Sbjct: 422 HFHIHQRVHTGEKPYKCDVCGKGFSHNSPLICHRRVHTGEKPYKCEACGKGFTRNTDLHI 481
Query: 225 KPPPHAQQAPLAACTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFK 284
H + P + + V ++ F+C C F
Sbjct: 482 HFRVHTGEKP-----------YKCKECGKGFSQASNLQVHQNVHTGEKRFKCETCGKGFS 530
Query: 285 KREELDRHIRIL--HKPYKCTLC--DFAASQE---EELISHVEKAHITAESAQGQG--PN 335
+ +L H R+ KPY+C +C DF+ S ++I EK + E +G N
Sbjct: 531 QSSKLQTHQRVHTGEKPYRCDVCGKDFSYSSNLKLHQVIHTGEKPYKCEECGKGFSWRSN 590
Query: 336 GGGEQSANE----FRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNH 391
Q + ++CE C + FSQA + H R H + C +CG+ F + L++H
Sbjct: 591 LHAHQRVHSGEKPYKCEQCDKSFSQAIDFRVHQRVHTGEKPYKCGVCGKGFSQSSGLQSH 650
Query: 392 MKVHLNKLSVK 402
+VH + K
Sbjct: 651 QRVHTGEKPYK 661
Score = 83.6 bits (205), Expect = 1e-15
Identities = 81/314 (25%), Positives = 116/314 (36%), Gaps = 41/314 (13%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH------K 181
+ Y C CGK F N+ L +H R HTGEKP+KC C +Q NL++H H K
Sbjct: 462 KPYKCEACGKGFTRNTDLHIHFRVHTGEKPYKCKECGKGFSQASNLQVHQNVHTGEKRFK 521
Query: 182 LGNLGKG---RGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAA- 237
GKG +++ R+ E+ D K L H + P
Sbjct: 522 CETCGKGFSQSSKLQTHQRV--HTGEKPYRCDVCGKDFSYSSNLKLHQVIHTGEKPYKCE 579
Query: 238 -CT--LALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFR-------------CTFCKG 281
C + ++N H P + + + A FR C C
Sbjct: 580 ECGKGFSWRSNLHAHQRVHSGEKPYKCEQCDKSFSQAIDFRVHQRVHTGEKPYKCGVCGK 639
Query: 282 KFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELISHV-----EKAHITAESAQGQGP 334
F + L H R+ KPYKC +C + I H EK + E +G G
Sbjct: 640 GFSQSSGLQSHQRVHTGEKPYKCDVCGKGFRYSSQFIYHQRGHTGEKPYKCEECGKGFGR 699
Query: 335 --NGGGEQSANEFR----CEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFL 388
N Q + CE CG+ FS L+ H+ H C+ CG+ F + L
Sbjct: 700 SLNLRHHQRVHTGEKPHICEECGKAFSLPSNLRVHLGVHTREKLFKCEECGKGFSQSARL 759
Query: 389 KNHMKVHLNKLSVK 402
+ H +VH + K
Sbjct: 760 EAHQRVHTGEKPYK 773
Score = 72.8 bits (177), Expect = 2e-12
Identities = 54/182 (29%), Positives = 76/182 (41%), Gaps = 14/182 (7%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR--KGEEDGLHVGLDERRGSGSDQESQSVSR 685
EKP +C +CG+ F H RVH ++ K EE G G S + + Q V R
Sbjct: 349 EKPYKCEECGKCFSQSSNFQCHQRVHTEEKPYKCEECGKGFGW-----SVNLRVHQRVHR 403
Query: 686 STTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDR- 744
P EE G G + + P D+ G+ P + R
Sbjct: 404 GEKPYKC---EECGKGFTQAAHFHIHQRVHTGEKPYKCDV---CGKGFSHNSPLICHRRV 457
Query: 745 SLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRE 804
G C CGK F + L +H R+HTGEKPYKC C +Q+++L+ H H E
Sbjct: 458 HTGEKPYKCEACGKGFTRNTDLHIHFRVHTGEKPYKCKECGKGFSQASNLQVHQNVHTGE 517
Query: 805 RQ 806
++
Sbjct: 518 KR 519
Score = 68.9 bits (167), Expect = 3e-11
Identities = 59/195 (30%), Positives = 83/195 (42%), Gaps = 20/195 (10%)
Query: 613 NQTLEYNLQGPGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERR 672
+Q +++ + + EKP +C CG+ F + H RVH ++ + D
Sbjct: 614 SQAIDFRVHQRVHTGEKPYKCGVCGKGFSQSSGLQSHQRVHTGEKPYKCDVC-------- 665
Query: 673 GSGSDQESQSV--SRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAG 730
G G SQ + R T EE G G G S + P I EE G
Sbjct: 666 GKGFRYSSQFIYHQRGHTGEKPYKCEECGKGFGRSLNLRHHQRVHTGEKPH---ICEECG 722
Query: 731 RSAGVQQPALLRDRSLGSAMKD----CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDY 786
++ + P+ LR LG ++ C CGK F S L+ H R+HTGEKPYKC CD
Sbjct: 723 KAFSL--PSNLRVH-LGVHTREKLFKCEECGKGFSQSARLEAHQRVHTGEKPYKCDICDK 779
Query: 787 AGTQSASLKYHLERH 801
+ L YH + H
Sbjct: 780 DFRHRSRLTYHQKVH 794
Score = 67.4 bits (163), Expect = 9e-11
Identities = 59/224 (26%), Positives = 91/224 (40%), Gaps = 28/224 (12%)
Query: 611 GLNQTLEYNLQGPGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDR--KGEEDG----- 663
G Q +++ + EKP +C CG+ F ++ H RVH ++ K E G
Sbjct: 416 GFTQAAHFHIHQRVHTGEKPYKCDVCGKGFSHNSPLICHRRVHTGEKPYKCEACGKGFTR 475
Query: 664 ---------LHVGLDERR----GSGSDQESQ-SVSRSTTPGSSNVTEESGVGGGLSQTGS 709
+H G + G G Q S V ++ G E+ G G SQ+
Sbjct: 476 NTDLHIHFRVHTGEKPYKCKECGKGFSQASNLQVHQNVHTGEKRFKCET-CGKGFSQSSK 534
Query: 710 AQ-EDSPHPSS-PSSSDI-GEEAGRSAGVQQPALLRDRSLGSAMKDCPYCGKTFRTSHHL 766
Q H P D+ G++ S+ ++ ++ G C CGK F +L
Sbjct: 535 LQTHQRVHTGEKPYRCDVCGKDFSYSSNLKLHQVIHT---GEKPYKCEECGKGFSWRSNL 591
Query: 767 KVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQNGAG 810
H R+H+GEKPYKC CD + +Q+ + H H E+ G
Sbjct: 592 HAHQRVHSGEKPYKCEQCDKSFSQAIDFRVHQRVHTGEKPYKCG 635
Score = 64.3 bits (155), Expect = 7e-10
Identities = 53/182 (29%), Positives = 74/182 (40%), Gaps = 16/182 (8%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSD-QESQSVSRS 686
EKP +C +CG+ F + H RVH GE+ D+ D + Q V
Sbjct: 573 EKPYKCEECGKGFSWRSNLHAHQRVHS----GEKPYKCEQCDKSFSQAIDFRVHQRVHTG 628
Query: 687 TTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSS--PSSSDIGEEAGRSAGVQQPALLRDR 744
P V G G SQ+ Q + P D+ G+ + R
Sbjct: 629 EKPYKCGVC-----GKGFSQSSGLQSHQRVHTGEKPYKCDV---CGKGFRYSSQFIYHQR 680
Query: 745 S-LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHR 803
G C CGK F S +L+ H R+HTGEKP+ C C A + ++L+ HL H R
Sbjct: 681 GHTGEKPYKCEECGKGFGRSLNLRHHQRVHTGEKPHICEECGKAFSLPSNLRVHLGVHTR 740
Query: 804 ER 805
E+
Sbjct: 741 EK 742
Score = 62.8 bits (151), Expect = 2e-09
Identities = 54/199 (27%), Positives = 77/199 (38%), Gaps = 28/199 (14%)
Query: 608 LSHGLNQTLEYNLQGPGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVG 667
+S G NQ L + EKP C +CGR F ++ +H VH ++ + H+
Sbjct: 235 ISDGSNQKLP--------LGEKPHPCGECGRGFSYSPRLPLHPNVHTGEKCFSQSS-HLR 285
Query: 668 LDERRGSGSDQESQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGE 727
+R G N ESG S S Q + S G+
Sbjct: 286 THQRIHPGE--------------KLNRCHESGDCFNKSSFHSYQSNHTGEKSYRCDSCGK 331
Query: 728 EAGRSAGVQQPALLRDRS-LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDY 786
S G+ ++ R+ G C CGK F S + + H R+HT EKPYKC C
Sbjct: 332 GFSSSTGL----IIHYRTHTGEKPYKCEECGKCFSQSSNFQCHQRVHTEEKPYKCEECGK 387
Query: 787 AGTQSASLKYHLERHHRER 805
S +L+ H H E+
Sbjct: 388 GFGWSVNLRVHQRVHRGEK 406
Score = 60.5 bits (145), Expect = 1e-08
Identities = 69/293 (23%), Positives = 100/293 (34%), Gaps = 61/293 (20%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGK 187
+ +PC CG+ F ++ L LH HTGEK F + HLRTH+ + G+
Sbjct: 248 KPHPCGECGRGFSYSPRLPLHPNVHTGEKCF-------------SQSSHLRTHQRIHPGE 294
Query: 188 GRGRVREENRLLHELE----------ERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAA 237
R E ++ E++ D KG + H + P
Sbjct: 295 KLNRCHESGDCFNKSSFHSYQSNHTGEKSYRCDSCGKGFSSSTGLIIHYRTHTGEKPYKC 354
Query: 238 --C--TLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHI 293
C + +N H P ++C C F L H
Sbjct: 355 EECGKCFSQSSNFQCHQRVHTEEKP---------------YKCEECGKGFGWSVNLRVHQ 399
Query: 294 RILH--KPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCG 351
R+ KPYKC C +Q HI G+ P ++C+VCG
Sbjct: 400 RVHRGEKPYKCEECGKGFTQAAHF-------HIHQRVHTGEKP----------YKCDVCG 442
Query: 352 QVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKNK 404
+ FS L H R H + C+ CG+ F L H +VH + K K
Sbjct: 443 KGFSHNSPLICHRRVHTGEKPYKCEACGKGFTRNTDLHIHFRVHTGEKPYKCK 495
Score = 60.5 bits (145), Expect = 1e-08
Identities = 50/179 (27%), Positives = 70/179 (39%), Gaps = 10/179 (5%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP +C C + F VH RVH ++ + G + G Q Q V
Sbjct: 601 EKPYKCEQCDKSFSQAIDFRVHQRVHTGEKPYKCGVCGKGFSQSSGL---QSHQRVHTGE 657
Query: 688 TPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSP-SSSDIGEEAGRSAGVQQPALLRDRSL 746
P +V G G S + P + G+ GRS ++ +
Sbjct: 658 KPYKCDVC---GKGFRYSSQFIYHQRGHTGEKPYKCEECGKGFGRSLNLRHHQRVHT--- 711
Query: 747 GSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
G C CGK F +L+VHL +HT EK +KC C +QSA L+ H H E+
Sbjct: 712 GEKPHICEECGKAFSLPSNLRVHLGVHTREKLFKCEECGKGFSQSARLEAHQRVHTGEK 770
Score = 58.2 bits (139), Expect = 5e-08
Identities = 28/69 (40%), Positives = 38/69 (55%), Gaps = 3/69 (4%)
Query: 115 SQMSDIEDDARKN---RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKG 171
SQ S ++ R + + Y C +CGK FR++S H R HTGEKP+KC C +
Sbjct: 642 SQSSGLQSHQRVHTGEKPYKCDVCGKGFRYSSQFIYHQRGHTGEKPYKCEECGKGFGRSL 701
Query: 172 NLKIHLRTH 180
NL+ H R H
Sbjct: 702 NLRHHQRVH 710
Score = 52.4 bits (124), Expect = 3e-06
Identities = 21/55 (38%), Positives = 29/55 (52%)
Query: 126 KNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
+ + + C CGK F ++ L H R HTGEKP+KC CD + L H + H
Sbjct: 740 REKLFKCEECGKGFSQSARLEAHQRVHTGEKPYKCDICDKDFRHRSRLTYHQKVH 794
Score = 43.9 bits (102), Expect = 0.001
Identities = 44/157 (28%), Positives = 59/157 (37%), Gaps = 22/157 (14%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR--KGEEDGLHVGLDERRGSGSDQESQSVSR 685
EKP +C CG+ FR Q + H R H ++ K EE G +G G + R
Sbjct: 657 EKPYKCDVCGKGFRYSSQFIYHQRGHTGEKPYKCEECG--------KGFGRSLNLRHHQR 708
Query: 686 STTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIG--EEAGRSAGVQQPALLRD 743
T ++ EE G L H + + EE G+ G Q A L
Sbjct: 709 VHTGEKPHICEECGKAFSLPSNLRV-----HLGVHTREKLFKCEECGK--GFSQSARLEA 761
Query: 744 RS---LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEK 777
G C C K FR L H ++HTG+K
Sbjct: 762 HQRVHTGEKPYKCDICDKDFRHRSRLTYHQKVHTGKK 798
Score = 36.6 bits (83), Expect = 0.16
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 9/62 (14%)
Query: 746 LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
LG C CG+ F S L +H +HTGEK + +QS+ L+ H H E+
Sbjct: 245 LGEKPHPCGECGRGFSYSPRLPLHPNVHTGEKCF---------SQSSHLRTHQRIHPGEK 295
Query: 806 QN 807
N
Sbjct: 296 LN 297
Score = 34.7 bits (78), Expect = 0.61
Identities = 13/29 (44%), Positives = 18/29 (62%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEK 156
+ Y C +C K FR S L+ H + HTG+K
Sbjct: 770 KPYKCDICDKDFRHRSRLTYHQKVHTGKK 798
>gi|153791350 replication initiator 1 isoform 1 [Homo sapiens]
Length = 567
Score = 100 bits (248), Expect = 1e-20
Identities = 87/337 (25%), Positives = 122/337 (36%), Gaps = 62/337 (18%)
Query: 63 SLEEKAHVPMSGQPMGSQMALLANQLGREVDTSLNGRVDLQQFLNGQNLGIMSQMSDIED 122
+LEE A + +P G G VD ++F + NL ++ E
Sbjct: 203 ALEEAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGE- 261
Query: 123 DARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKL 182
R + CP CGKRF L+ H R HTGEKP+ C C R K NL H + H
Sbjct: 262 -----RPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIH-- 314
Query: 183 GNLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTLAL 242
K+ +GS P P + Q P A
Sbjct: 315 ----------------------------KRSEGS-----AQAAPGPGSPQLPAGPQESAA 341
Query: 243 QANHSVP--DVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIR--ILHK 298
+ +VP P P P Q+ AP + + C C F+ L H R +
Sbjct: 342 EPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGER 401
Query: 299 PYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAW 358
P+ C C ++ L++H + H G+ P F CE CG+ FSQ
Sbjct: 402 PFTCAECGKNFGKKTHLVAH-SRVH------SGERP----------FACEECGRRFSQGS 444
Query: 359 FLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
L H R H C CG+ F+ +L H ++H
Sbjct: 445 HLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIH 481
Score = 77.0 bits (188), Expect = 1e-13
Identities = 76/295 (25%), Positives = 108/295 (36%), Gaps = 42/295 (14%)
Query: 131 PCPLCGKRFRFNSILSLHMRTHTGEKP---FKCPYCDHRAAQKGNLKIHLRTHKLGNLGK 187
PCP CG+RFR L+LH + H P F C C L +HLR H
Sbjct: 86 PCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAA---- 141
Query: 188 GRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTLALQANHS 247
+ + ER R KQL+ L + P P P A+ C +
Sbjct: 142 -------KRPIACPKCERRFWRRKQLRAHLRRCHP---PAPEARPFICGNCGRSFAQWDQ 191
Query: 248 VPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRILHKPYKCTLCDF 307
+ VAH A E+A A A G R R D + +P++C C
Sbjct: 192 L--VAHK--RVHVAEALEEAAAKALGPRPRGRPAVTAPRPGGDA----VDRPFQCACCGK 243
Query: 308 AASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKH 367
+ LI+H + H G+ P+ +C CG+ F+ +L H R H
Sbjct: 244 RFRHKPNLIAH-RRVHT------GERPH----------QCPECGKRFTNKPYLTSHRRIH 286
Query: 368 KDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKNKSPSDPEVPVPMGGMSQEA 422
+ C+ CGRRF+ L +H K+H +P +P G A
Sbjct: 287 TGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESAA 341
Score = 68.9 bits (167), Expect = 3e-11
Identities = 52/188 (27%), Positives = 73/188 (38%), Gaps = 29/188 (15%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP C +CGR FR ++ HS++HKR + G GS Q S
Sbjct: 289 EKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAA--------PGPGSPQLPAGPQESA 340
Query: 688 TPGSSNVTEESGVGGGLSQTGSAQEDSP-----HPSSPSSSDIG----EEAGRSAGVQQP 738
+ V + AQE P HP P + ++ GRS +++
Sbjct: 341 AEPTPAVPLKP-----------AQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERF 389
Query: 739 ALLRDRS-LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYH 797
R G C CGK F HL H R+H+GE+P+ C C +Q + L H
Sbjct: 390 LRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAH 449
Query: 798 LERHHRER 805
H +R
Sbjct: 450 RRDHAPDR 457
Score = 67.8 bits (164), Expect = 7e-11
Identities = 53/176 (30%), Positives = 75/176 (42%), Gaps = 16/176 (9%)
Query: 633 CPDCGRVFRTYHQVVVHSRVHKRDRKGE--EDGLHVGLDERRGSGSDQESQSVSRSTTPG 690
C DCGR FR + H R H +R E G + G +++ V+ S
Sbjct: 377 CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFG----------KKTHLVAHSRVHS 426
Query: 691 SSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSLGSAM 750
G SQ GS +P + + G+ A +P L R + +
Sbjct: 427 GERPFACEECGRRFSQ-GSHLAAHRRDHAPDRPFVCPDCGK-AFRHKPYLAAHRRIHTGE 484
Query: 751 KD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRE 804
K CP CGK F +L H RIHTGE+PY CP CD + +Q ++L H + H R+
Sbjct: 485 KPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRD 540
Score = 63.2 bits (152), Expect = 2e-09
Identities = 30/73 (41%), Positives = 38/73 (52%)
Query: 108 GQNLGIMSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRA 167
G+ S ++ D +R + CP CGK FR L+ H R HTGEKP+ CP C
Sbjct: 437 GRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAF 496
Query: 168 AQKGNLKIHLRTH 180
+QK NL H R H
Sbjct: 497 SQKSNLVSHRRIH 509
Score = 62.8 bits (151), Expect = 2e-09
Identities = 37/81 (45%), Positives = 42/81 (51%), Gaps = 3/81 (3%)
Query: 727 EEAGR--SAGVQQPALLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHC 784
EE GR S G A RD + CP CGK FR +L H RIHTGEKPY CP C
Sbjct: 434 EECGRRFSQGSHLAAHRRDHAPDRPFV-CPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDC 492
Query: 785 DYAGTQSASLKYHLERHHRER 805
A +Q ++L H H ER
Sbjct: 493 GKAFSQKSNLVSHRRIHTGER 513
Score = 61.6 bits (148), Expect = 5e-09
Identities = 53/200 (26%), Positives = 69/200 (34%), Gaps = 40/200 (20%)
Query: 623 PGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQS 682
P + +P C +CGR F + Q+V H RVH + L+E +
Sbjct: 169 PPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAE----------ALEEAAAKALGPRPRG 218
Query: 683 VSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLR 742
T P + G D P + + P L+
Sbjct: 219 RPAVTAP----------------RPGGDAVDRPFQCACCGKRFRHK---------PNLIA 253
Query: 743 DRSL--GSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLER 800
R + G CP CGK F +L H RIHTGEKPY C C +L H +
Sbjct: 254 HRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKI 313
Query: 801 HHRER---QNGAGPLSGQPP 817
H R Q GP S Q P
Sbjct: 314 HKRSEGSAQAAPGPGSPQLP 333
Score = 60.5 bits (145), Expect = 1e-08
Identities = 26/53 (49%), Positives = 32/53 (60%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
+ Y CP CGK F S L H R HTGE+P+ CP CD +QK NL H ++H
Sbjct: 485 KPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSH 537
Score = 56.2 bits (134), Expect = 2e-07
Identities = 42/129 (32%), Positives = 53/129 (41%), Gaps = 19/129 (14%)
Query: 269 APAAGFRCTFCKGKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELISHVEKAHITA 326
AP F C C F+ + L H RI KPY C C A SQ+ L+SH + H
Sbjct: 454 APDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSH-RRIHT-- 510
Query: 327 ESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPW 386
G+ P + C C + FSQ L H + H CC ICG+ F +
Sbjct: 511 ----GERP----------YACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEE 556
Query: 387 FLKNHMKVH 395
L H K H
Sbjct: 557 RLLAHQKKH 565
Score = 36.6 bits (83), Expect = 0.16
Identities = 14/30 (46%), Positives = 18/30 (60%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR 657
EKP CPDCG+ F +V H R+H +R
Sbjct: 484 EKPYVCPDCGKAFSQKSNLVSHRRIHTGER 513
Score = 34.7 bits (78), Expect = 0.61
Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKP---YKCPHCDYAGTQSASLKYHLERHHRERQNGA 809
CP CG+ FR + L +H ++H P + C C + +L HL H ++ A
Sbjct: 87 CPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIA 146
Query: 810 GP 811
P
Sbjct: 147 CP 148
Score = 34.3 bits (77), Expect = 0.80
Identities = 16/53 (30%), Positives = 22/53 (41%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
R Y CP C + F S L H ++H + F C C + L H + H
Sbjct: 513 RPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565
Score = 33.5 bits (75), Expect = 1.4
Identities = 11/30 (36%), Positives = 18/30 (60%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR 657
++P CPDCG+ FR + H R+H ++
Sbjct: 456 DRPFVCPDCGKAFRHKPYLAAHRRIHTGEK 485
Score = 32.3 bits (72), Expect = 3.0
Identities = 19/59 (32%), Positives = 25/59 (42%)
Query: 337 GGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
G + RC C + F L H R+ + C CGRRF+ FL H +VH
Sbjct: 49 GAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVH 107
Score = 32.3 bits (72), Expect = 3.0
Identities = 12/29 (41%), Positives = 16/29 (55%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRD 656
E+P CPDC R F ++ H + H RD
Sbjct: 512 ERPYACPDCDRSFSQKSNLITHRKSHIRD 540
>gi|153792539 replication initiator 1 isoform 1 [Homo sapiens]
Length = 567
Score = 100 bits (248), Expect = 1e-20
Identities = 87/337 (25%), Positives = 122/337 (36%), Gaps = 62/337 (18%)
Query: 63 SLEEKAHVPMSGQPMGSQMALLANQLGREVDTSLNGRVDLQQFLNGQNLGIMSQMSDIED 122
+LEE A + +P G G VD ++F + NL ++ E
Sbjct: 203 ALEEAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGE- 261
Query: 123 DARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKL 182
R + CP CGKRF L+ H R HTGEKP+ C C R K NL H + H
Sbjct: 262 -----RPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIH-- 314
Query: 183 GNLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTLAL 242
K+ +GS P P + Q P A
Sbjct: 315 ----------------------------KRSEGS-----AQAAPGPGSPQLPAGPQESAA 341
Query: 243 QANHSVP--DVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIR--ILHK 298
+ +VP P P P Q+ AP + + C C F+ L H R +
Sbjct: 342 EPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGER 401
Query: 299 PYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAW 358
P+ C C ++ L++H + H G+ P F CE CG+ FSQ
Sbjct: 402 PFTCAECGKNFGKKTHLVAH-SRVH------SGERP----------FACEECGRRFSQGS 444
Query: 359 FLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
L H R H C CG+ F+ +L H ++H
Sbjct: 445 HLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIH 481
Score = 77.0 bits (188), Expect = 1e-13
Identities = 76/295 (25%), Positives = 108/295 (36%), Gaps = 42/295 (14%)
Query: 131 PCPLCGKRFRFNSILSLHMRTHTGEKP---FKCPYCDHRAAQKGNLKIHLRTHKLGNLGK 187
PCP CG+RFR L+LH + H P F C C L +HLR H
Sbjct: 86 PCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAA---- 141
Query: 188 GRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTLALQANHS 247
+ + ER R KQL+ L + P P P A+ C +
Sbjct: 142 -------KRPIACPKCERRFWRRKQLRAHLRRCHP---PAPEARPFICGNCGRSFAQWDQ 191
Query: 248 VPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRILHKPYKCTLCDF 307
+ VAH A E+A A A G R R D + +P++C C
Sbjct: 192 L--VAHK--RVHVAEALEEAAAKALGPRPRGRPAVTAPRPGGDA----VDRPFQCACCGK 243
Query: 308 AASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKH 367
+ LI+H + H G+ P+ +C CG+ F+ +L H R H
Sbjct: 244 RFRHKPNLIAH-RRVHT------GERPH----------QCPECGKRFTNKPYLTSHRRIH 286
Query: 368 KDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKNKSPSDPEVPVPMGGMSQEA 422
+ C+ CGRRF+ L +H K+H +P +P G A
Sbjct: 287 TGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESAA 341
Score = 68.9 bits (167), Expect = 3e-11
Identities = 52/188 (27%), Positives = 73/188 (38%), Gaps = 29/188 (15%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP C +CGR FR ++ HS++HKR + G GS Q S
Sbjct: 289 EKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAA--------PGPGSPQLPAGPQESA 340
Query: 688 TPGSSNVTEESGVGGGLSQTGSAQEDSP-----HPSSPSSSDIG----EEAGRSAGVQQP 738
+ V + AQE P HP P + ++ GRS +++
Sbjct: 341 AEPTPAVPLKP-----------AQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERF 389
Query: 739 ALLRDRS-LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYH 797
R G C CGK F HL H R+H+GE+P+ C C +Q + L H
Sbjct: 390 LRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAH 449
Query: 798 LERHHRER 805
H +R
Sbjct: 450 RRDHAPDR 457
Score = 67.8 bits (164), Expect = 7e-11
Identities = 53/176 (30%), Positives = 75/176 (42%), Gaps = 16/176 (9%)
Query: 633 CPDCGRVFRTYHQVVVHSRVHKRDRKGE--EDGLHVGLDERRGSGSDQESQSVSRSTTPG 690
C DCGR FR + H R H +R E G + G +++ V+ S
Sbjct: 377 CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFG----------KKTHLVAHSRVHS 426
Query: 691 SSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSLGSAM 750
G SQ GS +P + + G+ A +P L R + +
Sbjct: 427 GERPFACEECGRRFSQ-GSHLAAHRRDHAPDRPFVCPDCGK-AFRHKPYLAAHRRIHTGE 484
Query: 751 KD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRE 804
K CP CGK F +L H RIHTGE+PY CP CD + +Q ++L H + H R+
Sbjct: 485 KPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRD 540
Score = 63.2 bits (152), Expect = 2e-09
Identities = 30/73 (41%), Positives = 38/73 (52%)
Query: 108 GQNLGIMSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRA 167
G+ S ++ D +R + CP CGK FR L+ H R HTGEKP+ CP C
Sbjct: 437 GRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAF 496
Query: 168 AQKGNLKIHLRTH 180
+QK NL H R H
Sbjct: 497 SQKSNLVSHRRIH 509
Score = 62.8 bits (151), Expect = 2e-09
Identities = 37/81 (45%), Positives = 42/81 (51%), Gaps = 3/81 (3%)
Query: 727 EEAGR--SAGVQQPALLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHC 784
EE GR S G A RD + CP CGK FR +L H RIHTGEKPY CP C
Sbjct: 434 EECGRRFSQGSHLAAHRRDHAPDRPFV-CPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDC 492
Query: 785 DYAGTQSASLKYHLERHHRER 805
A +Q ++L H H ER
Sbjct: 493 GKAFSQKSNLVSHRRIHTGER 513
Score = 61.6 bits (148), Expect = 5e-09
Identities = 53/200 (26%), Positives = 69/200 (34%), Gaps = 40/200 (20%)
Query: 623 PGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQS 682
P + +P C +CGR F + Q+V H RVH + L+E +
Sbjct: 169 PPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAE----------ALEEAAAKALGPRPRG 218
Query: 683 VSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLR 742
T P + G D P + + P L+
Sbjct: 219 RPAVTAP----------------RPGGDAVDRPFQCACCGKRFRHK---------PNLIA 253
Query: 743 DRSL--GSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLER 800
R + G CP CGK F +L H RIHTGEKPY C C +L H +
Sbjct: 254 HRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKI 313
Query: 801 HHRER---QNGAGPLSGQPP 817
H R Q GP S Q P
Sbjct: 314 HKRSEGSAQAAPGPGSPQLP 333
Score = 60.5 bits (145), Expect = 1e-08
Identities = 26/53 (49%), Positives = 32/53 (60%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
+ Y CP CGK F S L H R HTGE+P+ CP CD +QK NL H ++H
Sbjct: 485 KPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSH 537
Score = 56.2 bits (134), Expect = 2e-07
Identities = 42/129 (32%), Positives = 53/129 (41%), Gaps = 19/129 (14%)
Query: 269 APAAGFRCTFCKGKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELISHVEKAHITA 326
AP F C C F+ + L H RI KPY C C A SQ+ L+SH + H
Sbjct: 454 APDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSH-RRIHT-- 510
Query: 327 ESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPW 386
G+ P + C C + FSQ L H + H CC ICG+ F +
Sbjct: 511 ----GERP----------YACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEE 556
Query: 387 FLKNHMKVH 395
L H K H
Sbjct: 557 RLLAHQKKH 565
Score = 36.6 bits (83), Expect = 0.16
Identities = 14/30 (46%), Positives = 18/30 (60%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR 657
EKP CPDCG+ F +V H R+H +R
Sbjct: 484 EKPYVCPDCGKAFSQKSNLVSHRRIHTGER 513
Score = 34.7 bits (78), Expect = 0.61
Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKP---YKCPHCDYAGTQSASLKYHLERHHRERQNGA 809
CP CG+ FR + L +H ++H P + C C + +L HL H ++ A
Sbjct: 87 CPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIA 146
Query: 810 GP 811
P
Sbjct: 147 CP 148
Score = 34.3 bits (77), Expect = 0.80
Identities = 16/53 (30%), Positives = 22/53 (41%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
R Y CP C + F S L H ++H + F C C + L H + H
Sbjct: 513 RPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565
Score = 33.5 bits (75), Expect = 1.4
Identities = 11/30 (36%), Positives = 18/30 (60%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR 657
++P CPDCG+ FR + H R+H ++
Sbjct: 456 DRPFVCPDCGKAFRHKPYLAAHRRIHTGEK 485
Score = 32.3 bits (72), Expect = 3.0
Identities = 19/59 (32%), Positives = 25/59 (42%)
Query: 337 GGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
G + RC C + F L H R+ + C CGRRF+ FL H +VH
Sbjct: 49 GAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVH 107
Score = 32.3 bits (72), Expect = 3.0
Identities = 12/29 (41%), Positives = 16/29 (55%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRD 656
E+P CPDC R F ++ H + H RD
Sbjct: 512 ERPYACPDCDRSFSQKSNLITHRKSHIRD 540
>gi|153792647 replication initiator 1 isoform 3 [Homo sapiens]
Length = 624
Score = 100 bits (248), Expect = 1e-20
Identities = 87/337 (25%), Positives = 122/337 (36%), Gaps = 62/337 (18%)
Query: 63 SLEEKAHVPMSGQPMGSQMALLANQLGREVDTSLNGRVDLQQFLNGQNLGIMSQMSDIED 122
+LEE A + +P G G VD ++F + NL ++ E
Sbjct: 260 ALEEAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGE- 318
Query: 123 DARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKL 182
R + CP CGKRF L+ H R HTGEKP+ C C R K NL H + H
Sbjct: 319 -----RPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIH-- 371
Query: 183 GNLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTLAL 242
K+ +GS P P + Q P A
Sbjct: 372 ----------------------------KRSEGS-----AQAAPGPGSPQLPAGPQESAA 398
Query: 243 QANHSVP--DVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIR--ILHK 298
+ +VP P P P Q+ AP + + C C F+ L H R +
Sbjct: 399 EPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGER 458
Query: 299 PYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAW 358
P+ C C ++ L++H + H G+ P F CE CG+ FSQ
Sbjct: 459 PFTCAECGKNFGKKTHLVAH-SRVH------SGERP----------FACEECGRRFSQGS 501
Query: 359 FLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
L H R H C CG+ F+ +L H ++H
Sbjct: 502 HLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIH 538
Score = 77.0 bits (188), Expect = 1e-13
Identities = 76/295 (25%), Positives = 108/295 (36%), Gaps = 42/295 (14%)
Query: 131 PCPLCGKRFRFNSILSLHMRTHTGEKP---FKCPYCDHRAAQKGNLKIHLRTHKLGNLGK 187
PCP CG+RFR L+LH + H P F C C L +HLR H
Sbjct: 143 PCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAA---- 198
Query: 188 GRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTLALQANHS 247
+ + ER R KQL+ L + P P P A+ C +
Sbjct: 199 -------KRPIACPKCERRFWRRKQLRAHLRRCHP---PAPEARPFICGNCGRSFAQWDQ 248
Query: 248 VPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRILHKPYKCTLCDF 307
+ VAH A E+A A A G R R D + +P++C C
Sbjct: 249 L--VAHK--RVHVAEALEEAAAKALGPRPRGRPAVTAPRPGGDA----VDRPFQCACCGK 300
Query: 308 AASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKH 367
+ LI+H + H G+ P+ +C CG+ F+ +L H R H
Sbjct: 301 RFRHKPNLIAH-RRVHT------GERPH----------QCPECGKRFTNKPYLTSHRRIH 343
Query: 368 KDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKNKSPSDPEVPVPMGGMSQEA 422
+ C+ CGRRF+ L +H K+H +P +P G A
Sbjct: 344 TGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESAA 398
Score = 68.9 bits (167), Expect = 3e-11
Identities = 52/188 (27%), Positives = 73/188 (38%), Gaps = 29/188 (15%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP C +CGR FR ++ HS++HKR + G GS Q S
Sbjct: 346 EKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAA--------PGPGSPQLPAGPQESA 397
Query: 688 TPGSSNVTEESGVGGGLSQTGSAQEDSP-----HPSSPSSSDIG----EEAGRSAGVQQP 738
+ V + AQE P HP P + ++ GRS +++
Sbjct: 398 AEPTPAVPLKP-----------AQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERF 446
Query: 739 ALLRDRS-LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYH 797
R G C CGK F HL H R+H+GE+P+ C C +Q + L H
Sbjct: 447 LRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAH 506
Query: 798 LERHHRER 805
H +R
Sbjct: 507 RRDHAPDR 514
Score = 67.8 bits (164), Expect = 7e-11
Identities = 53/176 (30%), Positives = 75/176 (42%), Gaps = 16/176 (9%)
Query: 633 CPDCGRVFRTYHQVVVHSRVHKRDRKGE--EDGLHVGLDERRGSGSDQESQSVSRSTTPG 690
C DCGR FR + H R H +R E G + G +++ V+ S
Sbjct: 434 CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFG----------KKTHLVAHSRVHS 483
Query: 691 SSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSLGSAM 750
G SQ GS +P + + G+ A +P L R + +
Sbjct: 484 GERPFACEECGRRFSQ-GSHLAAHRRDHAPDRPFVCPDCGK-AFRHKPYLAAHRRIHTGE 541
Query: 751 KD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRE 804
K CP CGK F +L H RIHTGE+PY CP CD + +Q ++L H + H R+
Sbjct: 542 KPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRD 597
Score = 63.2 bits (152), Expect = 2e-09
Identities = 30/73 (41%), Positives = 38/73 (52%)
Query: 108 GQNLGIMSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRA 167
G+ S ++ D +R + CP CGK FR L+ H R HTGEKP+ CP C
Sbjct: 494 GRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAF 553
Query: 168 AQKGNLKIHLRTH 180
+QK NL H R H
Sbjct: 554 SQKSNLVSHRRIH 566
Score = 62.8 bits (151), Expect = 2e-09
Identities = 37/81 (45%), Positives = 42/81 (51%), Gaps = 3/81 (3%)
Query: 727 EEAGR--SAGVQQPALLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHC 784
EE GR S G A RD + CP CGK FR +L H RIHTGEKPY CP C
Sbjct: 491 EECGRRFSQGSHLAAHRRDHAPDRPFV-CPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDC 549
Query: 785 DYAGTQSASLKYHLERHHRER 805
A +Q ++L H H ER
Sbjct: 550 GKAFSQKSNLVSHRRIHTGER 570
Score = 61.6 bits (148), Expect = 5e-09
Identities = 53/200 (26%), Positives = 69/200 (34%), Gaps = 40/200 (20%)
Query: 623 PGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQS 682
P + +P C +CGR F + Q+V H RVH + L+E +
Sbjct: 226 PPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAE----------ALEEAAAKALGPRPRG 275
Query: 683 VSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLR 742
T P + G D P + + P L+
Sbjct: 276 RPAVTAP----------------RPGGDAVDRPFQCACCGKRFRHK---------PNLIA 310
Query: 743 DRSL--GSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLER 800
R + G CP CGK F +L H RIHTGEKPY C C +L H +
Sbjct: 311 HRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKI 370
Query: 801 HHRER---QNGAGPLSGQPP 817
H R Q GP S Q P
Sbjct: 371 HKRSEGSAQAAPGPGSPQLP 390
Score = 60.5 bits (145), Expect = 1e-08
Identities = 26/53 (49%), Positives = 32/53 (60%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
+ Y CP CGK F S L H R HTGE+P+ CP CD +QK NL H ++H
Sbjct: 542 KPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSH 594
Score = 56.2 bits (134), Expect = 2e-07
Identities = 42/129 (32%), Positives = 53/129 (41%), Gaps = 19/129 (14%)
Query: 269 APAAGFRCTFCKGKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELISHVEKAHITA 326
AP F C C F+ + L H RI KPY C C A SQ+ L+SH + H
Sbjct: 511 APDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSH-RRIHT-- 567
Query: 327 ESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPW 386
G+ P + C C + FSQ L H + H CC ICG+ F +
Sbjct: 568 ----GERP----------YACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEE 613
Query: 387 FLKNHMKVH 395
L H K H
Sbjct: 614 RLLAHQKKH 622
Score = 36.6 bits (83), Expect = 0.16
Identities = 14/30 (46%), Positives = 18/30 (60%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR 657
EKP CPDCG+ F +V H R+H +R
Sbjct: 541 EKPYVCPDCGKAFSQKSNLVSHRRIHTGER 570
Score = 34.7 bits (78), Expect = 0.61
Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKP---YKCPHCDYAGTQSASLKYHLERHHRERQNGA 809
CP CG+ FR + L +H ++H P + C C + +L HL H ++ A
Sbjct: 144 CPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIA 203
Query: 810 GP 811
P
Sbjct: 204 CP 205
Score = 34.3 bits (77), Expect = 0.80
Identities = 16/53 (30%), Positives = 22/53 (41%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
R Y CP C + F S L H ++H + F C C + L H + H
Sbjct: 570 RPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 622
Score = 33.5 bits (75), Expect = 1.4
Identities = 11/30 (36%), Positives = 18/30 (60%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR 657
++P CPDCG+ FR + H R+H ++
Sbjct: 513 DRPFVCPDCGKAFRHKPYLAAHRRIHTGEK 542
Score = 32.3 bits (72), Expect = 3.0
Identities = 19/59 (32%), Positives = 25/59 (42%)
Query: 337 GGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
G + RC C + F L H R+ + C CGRRF+ FL H +VH
Sbjct: 106 GAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVH 164
Score = 32.3 bits (72), Expect = 3.0
Identities = 12/29 (41%), Positives = 16/29 (55%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRD 656
E+P CPDC R F ++ H + H RD
Sbjct: 569 ERPYACPDCDRSFSQKSNLITHRKSHIRD 597
>gi|153791994 replication initiator 1 isoform 1 [Homo sapiens]
Length = 567
Score = 100 bits (248), Expect = 1e-20
Identities = 87/337 (25%), Positives = 122/337 (36%), Gaps = 62/337 (18%)
Query: 63 SLEEKAHVPMSGQPMGSQMALLANQLGREVDTSLNGRVDLQQFLNGQNLGIMSQMSDIED 122
+LEE A + +P G G VD ++F + NL ++ E
Sbjct: 203 ALEEAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGE- 261
Query: 123 DARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKL 182
R + CP CGKRF L+ H R HTGEKP+ C C R K NL H + H
Sbjct: 262 -----RPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIH-- 314
Query: 183 GNLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTLAL 242
K+ +GS P P + Q P A
Sbjct: 315 ----------------------------KRSEGS-----AQAAPGPGSPQLPAGPQESAA 341
Query: 243 QANHSVP--DVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIR--ILHK 298
+ +VP P P P Q+ AP + + C C F+ L H R +
Sbjct: 342 EPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGER 401
Query: 299 PYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAW 358
P+ C C ++ L++H + H G+ P F CE CG+ FSQ
Sbjct: 402 PFTCAECGKNFGKKTHLVAH-SRVH------SGERP----------FACEECGRRFSQGS 444
Query: 359 FLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
L H R H C CG+ F+ +L H ++H
Sbjct: 445 HLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIH 481
Score = 77.0 bits (188), Expect = 1e-13
Identities = 76/295 (25%), Positives = 108/295 (36%), Gaps = 42/295 (14%)
Query: 131 PCPLCGKRFRFNSILSLHMRTHTGEKP---FKCPYCDHRAAQKGNLKIHLRTHKLGNLGK 187
PCP CG+RFR L+LH + H P F C C L +HLR H
Sbjct: 86 PCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAA---- 141
Query: 188 GRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTLALQANHS 247
+ + ER R KQL+ L + P P P A+ C +
Sbjct: 142 -------KRPIACPKCERRFWRRKQLRAHLRRCHP---PAPEARPFICGNCGRSFAQWDQ 191
Query: 248 VPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRILHKPYKCTLCDF 307
+ VAH A E+A A A G R R D + +P++C C
Sbjct: 192 L--VAHK--RVHVAEALEEAAAKALGPRPRGRPAVTAPRPGGDA----VDRPFQCACCGK 243
Query: 308 AASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKH 367
+ LI+H + H G+ P+ +C CG+ F+ +L H R H
Sbjct: 244 RFRHKPNLIAH-RRVHT------GERPH----------QCPECGKRFTNKPYLTSHRRIH 286
Query: 368 KDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKNKSPSDPEVPVPMGGMSQEA 422
+ C+ CGRRF+ L +H K+H +P +P G A
Sbjct: 287 TGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESAA 341
Score = 68.9 bits (167), Expect = 3e-11
Identities = 52/188 (27%), Positives = 73/188 (38%), Gaps = 29/188 (15%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP C +CGR FR ++ HS++HKR + G GS Q S
Sbjct: 289 EKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAA--------PGPGSPQLPAGPQESA 340
Query: 688 TPGSSNVTEESGVGGGLSQTGSAQEDSP-----HPSSPSSSDIG----EEAGRSAGVQQP 738
+ V + AQE P HP P + ++ GRS +++
Sbjct: 341 AEPTPAVPLKP-----------AQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERF 389
Query: 739 ALLRDRS-LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYH 797
R G C CGK F HL H R+H+GE+P+ C C +Q + L H
Sbjct: 390 LRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAH 449
Query: 798 LERHHRER 805
H +R
Sbjct: 450 RRDHAPDR 457
Score = 67.8 bits (164), Expect = 7e-11
Identities = 53/176 (30%), Positives = 75/176 (42%), Gaps = 16/176 (9%)
Query: 633 CPDCGRVFRTYHQVVVHSRVHKRDRKGE--EDGLHVGLDERRGSGSDQESQSVSRSTTPG 690
C DCGR FR + H R H +R E G + G +++ V+ S
Sbjct: 377 CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFG----------KKTHLVAHSRVHS 426
Query: 691 SSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSLGSAM 750
G SQ GS +P + + G+ A +P L R + +
Sbjct: 427 GERPFACEECGRRFSQ-GSHLAAHRRDHAPDRPFVCPDCGK-AFRHKPYLAAHRRIHTGE 484
Query: 751 KD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRE 804
K CP CGK F +L H RIHTGE+PY CP CD + +Q ++L H + H R+
Sbjct: 485 KPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRD 540
Score = 63.2 bits (152), Expect = 2e-09
Identities = 30/73 (41%), Positives = 38/73 (52%)
Query: 108 GQNLGIMSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRA 167
G+ S ++ D +R + CP CGK FR L+ H R HTGEKP+ CP C
Sbjct: 437 GRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAF 496
Query: 168 AQKGNLKIHLRTH 180
+QK NL H R H
Sbjct: 497 SQKSNLVSHRRIH 509
Score = 62.8 bits (151), Expect = 2e-09
Identities = 37/81 (45%), Positives = 42/81 (51%), Gaps = 3/81 (3%)
Query: 727 EEAGR--SAGVQQPALLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHC 784
EE GR S G A RD + CP CGK FR +L H RIHTGEKPY CP C
Sbjct: 434 EECGRRFSQGSHLAAHRRDHAPDRPFV-CPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDC 492
Query: 785 DYAGTQSASLKYHLERHHRER 805
A +Q ++L H H ER
Sbjct: 493 GKAFSQKSNLVSHRRIHTGER 513
Score = 61.6 bits (148), Expect = 5e-09
Identities = 53/200 (26%), Positives = 69/200 (34%), Gaps = 40/200 (20%)
Query: 623 PGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQS 682
P + +P C +CGR F + Q+V H RVH + L+E +
Sbjct: 169 PPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAE----------ALEEAAAKALGPRPRG 218
Query: 683 VSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLR 742
T P + G D P + + P L+
Sbjct: 219 RPAVTAP----------------RPGGDAVDRPFQCACCGKRFRHK---------PNLIA 253
Query: 743 DRSL--GSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLER 800
R + G CP CGK F +L H RIHTGEKPY C C +L H +
Sbjct: 254 HRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKI 313
Query: 801 HHRER---QNGAGPLSGQPP 817
H R Q GP S Q P
Sbjct: 314 HKRSEGSAQAAPGPGSPQLP 333
Score = 60.5 bits (145), Expect = 1e-08
Identities = 26/53 (49%), Positives = 32/53 (60%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
+ Y CP CGK F S L H R HTGE+P+ CP CD +QK NL H ++H
Sbjct: 485 KPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSH 537
Score = 56.2 bits (134), Expect = 2e-07
Identities = 42/129 (32%), Positives = 53/129 (41%), Gaps = 19/129 (14%)
Query: 269 APAAGFRCTFCKGKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELISHVEKAHITA 326
AP F C C F+ + L H RI KPY C C A SQ+ L+SH + H
Sbjct: 454 APDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSH-RRIHT-- 510
Query: 327 ESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPW 386
G+ P + C C + FSQ L H + H CC ICG+ F +
Sbjct: 511 ----GERP----------YACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEE 556
Query: 387 FLKNHMKVH 395
L H K H
Sbjct: 557 RLLAHQKKH 565
Score = 36.6 bits (83), Expect = 0.16
Identities = 14/30 (46%), Positives = 18/30 (60%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR 657
EKP CPDCG+ F +V H R+H +R
Sbjct: 484 EKPYVCPDCGKAFSQKSNLVSHRRIHTGER 513
Score = 34.7 bits (78), Expect = 0.61
Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKP---YKCPHCDYAGTQSASLKYHLERHHRERQNGA 809
CP CG+ FR + L +H ++H P + C C + +L HL H ++ A
Sbjct: 87 CPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIA 146
Query: 810 GP 811
P
Sbjct: 147 CP 148
Score = 34.3 bits (77), Expect = 0.80
Identities = 16/53 (30%), Positives = 22/53 (41%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
R Y CP C + F S L H ++H + F C C + L H + H
Sbjct: 513 RPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565
Score = 33.5 bits (75), Expect = 1.4
Identities = 11/30 (36%), Positives = 18/30 (60%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR 657
++P CPDCG+ FR + H R+H ++
Sbjct: 456 DRPFVCPDCGKAFRHKPYLAAHRRIHTGEK 485
Score = 32.3 bits (72), Expect = 3.0
Identities = 19/59 (32%), Positives = 25/59 (42%)
Query: 337 GGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
G + RC C + F L H R+ + C CGRRF+ FL H +VH
Sbjct: 49 GAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVH 107
Score = 32.3 bits (72), Expect = 3.0
Identities = 12/29 (41%), Positives = 16/29 (55%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRD 656
E+P CPDC R F ++ H + H RD
Sbjct: 512 ERPYACPDCDRSFSQKSNLITHRKSHIRD 540
>gi|104294877 zinc finger protein 229 [Homo sapiens]
Length = 825
Score = 96.7 bits (239), Expect = 1e-19
Identities = 86/292 (29%), Positives = 115/292 (39%), Gaps = 44/292 (15%)
Query: 130 YPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH------KLG 183
Y C +CGK F ++S L +H R HTGEKP+KC C + +L IH R H K
Sbjct: 517 YKCNVCGKSFSYSSGLLMHQRLHTGEKPYKCE-CGKSFGRSSDLHIHQRVHTGEKPYKCS 575
Query: 184 NLGKGRGRVREENRLLHELE-----ERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAAC 238
GKG R N LH + ER + D KG + + H + P
Sbjct: 576 ECGKGFRR----NSDLHSHQRVHTGERPYVCDVCGKGFIYSSDLLIHQRVHTGEKPYKCA 631
Query: 239 TLALQANHSVPDVAHP--VPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRIL 296
++S + H KP QE GFRCT L +H R+
Sbjct: 632 ECGKGFSYSSGLLIHQRVHTGEKPYRCQE----CGKGFRCT---------SSLHKHQRVH 678
Query: 297 --HKPYKCTLCDFAASQEEELISHV-----EKAHITAESAQGQGPNGG------GEQSAN 343
KPY C C S L +H EK + E +G G
Sbjct: 679 TGKKPYTCDQCGKGFSYGSNLRTHQRLHTGEKPYTCCECGKGFRYGSGLLSHKRVHTGEK 738
Query: 344 EFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
+RC VCG+ +SQ+ L+GH R H + C+ CG+ F L H +VH
Sbjct: 739 PYRCHVCGKGYSQSSHLQGHQRVHTGEKPYKCEECGKGFGRNSCLHVHQRVH 790
Score = 84.7 bits (208), Expect = 5e-16
Identities = 72/304 (23%), Positives = 110/304 (36%), Gaps = 36/304 (11%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH------K 181
+ Y C CGK F ++S+L +H R HTGEKP+ C C K L H H
Sbjct: 403 KPYKCSECGKGFSYSSVLQVHQRLHTGEKPYTCSECGKGFCAKSALHKHQHIHPGEKPYS 462
Query: 182 LGNLGKGRG-RVREENRLLHELEERAILRDKQLKG----SLLQPRPDLKPPPHAQQAPLA 236
G GKG + ER DK KG S LQ + H + +
Sbjct: 463 CGECGKGFSCSSHLSSHQKTHTGERPYQCDKCGKGFSHNSYLQAHQRVHMGQHLYKCNVC 522
Query: 237 ACTLALQANHSVPDVAHPVPSP------------KPASVQEDAVAPAAGFRCTFCKGKFK 284
+ + + + H P + + ++C+ C F+
Sbjct: 523 GKSFSYSSGLLMHQRLHTGEKPYKCECGKSFGRSSDLHIHQRVHTGEKPYKCSECGKGFR 582
Query: 285 KREELDRHIRIL--HKPYKCTLCDFAASQEEELISHV-----EKAHITAESAQGQGPNGG 337
+ +L H R+ +PY C +C +L+ H EK + AE +G + G
Sbjct: 583 RNSDLHSHQRVHTGERPYVCDVCGKGFIYSSDLLIHQRVHTGEKPYKCAECGKGFSYSSG 642
Query: 338 ------GEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNH 391
+RC+ CG+ F L H R H + C CG+ F L+ H
Sbjct: 643 LLIHQRVHTGEKPYRCQECGKGFRCTSSLHKHQRVHTGKKPYTCDQCGKGFSYGSNLRTH 702
Query: 392 MKVH 395
++H
Sbjct: 703 QRLH 706
Score = 84.7 bits (208), Expect = 5e-16
Identities = 78/310 (25%), Positives = 110/310 (35%), Gaps = 57/310 (18%)
Query: 108 GQNLGIMSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRA 167
G++ G S + + + Y C CGK FR NS L H R HTGE+P+ C C
Sbjct: 550 GKSFGRSSDLHIHQRVHTGEKPYKCSECGKGFRRNSDLHSHQRVHTGERPYVCDVCGKGF 609
Query: 168 AQKGNLKIHLRTH------KLGNLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQPR 221
+L IH R H K GKG G L+ R
Sbjct: 610 IYSSDLLIHQRVHTGEKPYKCAECGKG---------------------FSYSSGLLIHQR 648
Query: 222 PDLKPPPHAQQ--APLAACTLALQANHSVPDVAHPVPSPKPAS---------VQEDAVAP 270
P+ Q CT +L + V P + +
Sbjct: 649 VHTGEKPYRCQECGKGFRCTSSLHKHQRVHTGKKPYTCDQCGKGFSYGSNLRTHQRLHTG 708
Query: 271 AAGFRCTFCKGKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELISHVEKAHITAES 328
+ C C F+ L H R+ KPY+C +C SQ L H ++ H
Sbjct: 709 EKPYTCCECGKGFRYGSGLLSHKRVHTGEKPYRCHVCGKGYSQSSHLQGH-QRVH----- 762
Query: 329 AQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFL 388
G+ P ++CE CG+ F + L H R H + C +CG+ F L
Sbjct: 763 -TGEKP----------YKCEECGKGFGRNSCLHVHQRVHTGEKPYTCGVCGKGFSYTSGL 811
Query: 389 KNHMKVHLNK 398
+NH +VHL +
Sbjct: 812 RNHQRVHLGE 821
Score = 81.3 bits (199), Expect = 6e-15
Identities = 70/283 (24%), Positives = 107/283 (37%), Gaps = 54/283 (19%)
Query: 130 YPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH------KLG 183
Y C +CGK FR+ S+L +H HTG +P+KC C + NL +H R H K
Sbjct: 349 YRCDVCGKGFRYKSVLLIHQGVHTGRRPYKCEECGKAFGRSSNLLVHQRVHTGEKPYKCS 408
Query: 184 NLGKG--RGRVREENRLLHELEERAILRD-------KQLKGSLLQPRPDLKPPPHAQQAP 234
GKG V + ++ LH E+ + K P KP +
Sbjct: 409 ECGKGFSYSSVLQVHQRLHTGEKPYTCSECGKGFCAKSALHKHQHIHPGEKPYSCGECGK 468
Query: 235 LAACTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIR 294
+C+ L ++ P ++C C F L H R
Sbjct: 469 GFSCSSHLSSHQKTHTGERP-------------------YQCDKCGKGFSHNSYLQAHQR 509
Query: 295 IL--HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQ 352
+ YKC +C + S L+ H ++ H G+ P ++CE CG+
Sbjct: 510 VHMGQHLYKCNVCGKSFSYSSGLLMH-QRLH------TGEKP----------YKCE-CGK 551
Query: 353 VFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
F ++ L H R H + C CG+ F+ L +H +VH
Sbjct: 552 SFGRSSDLHIHQRVHTGEKPYKCSECGKGFRRNSDLHSHQRVH 594
Score = 63.9 bits (154), Expect = 9e-10
Identities = 49/185 (26%), Positives = 74/185 (40%), Gaps = 12/185 (6%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP +C +CG+ F +++H RVH ++ G R + S + Q V
Sbjct: 625 EKPYKCAECGKGFSYSSGLLIHQRVHTGEKPYRCQECGKGF---RCTSSLHKHQRVHTGK 681
Query: 688 TPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSLG 747
P + + + G +T P + G G LL + +
Sbjct: 682 KPYTCDQCGKGFSYGSNLRTHQRLHTGEKPYTCCECGKGFRYGSG-------LLSHKRVH 734
Query: 748 SAMKD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
+ K C CGK + S HL+ H R+HTGEKPYKC C +++ L H H E+
Sbjct: 735 TGEKPYRCHVCGKGYSQSSHLQGHQRVHTGEKPYKCEECGKGFGRNSCLHVHQRVHTGEK 794
Query: 806 QNGAG 810
G
Sbjct: 795 PYTCG 799
Score = 62.4 bits (150), Expect = 3e-09
Identities = 51/197 (25%), Positives = 81/197 (41%), Gaps = 21/197 (10%)
Query: 629 KPTECPDCGRVFRTYHQVVVHSRVHKRDR--------KGEEDGLHVGLDERRGSGSDQES 680
+P +C +CG+ F ++VH RVH ++ KG + + +R +G +
Sbjct: 375 RPYKCEECGKAFGRSSNLLVHQRVHTGEKPYKCSECGKGFSYSSVLQVHQRLHTGEKPYT 434
Query: 681 QSVSRSTTPGSSNVTEESGVGGG-----LSQTGSAQEDSPHPSSPSSSDIGEEAGR---- 731
S S + + + G + G S H SS + GE +
Sbjct: 435 CSECGKGFCAKSALHKHQHIHPGEKPYSCGECGKGFSCSSHLSSHQKTHTGERPYQCDKC 494
Query: 732 SAGVQQPALLRDRS---LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAG 788
G + L+ +G + C CGK+F S L +H R+HTGEKPYKC C +
Sbjct: 495 GKGFSHNSYLQAHQRVHMGQHLYKCNVCGKSFSYSSGLLMHQRLHTGEKPYKC-ECGKSF 553
Query: 789 TQSASLKYHLERHHRER 805
+S+ L H H E+
Sbjct: 554 GRSSDLHIHQRVHTGEK 570
Score = 60.1 bits (144), Expect = 1e-08
Identities = 46/180 (25%), Positives = 70/180 (38%), Gaps = 13/180 (7%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP C +CG+ F + H + H +R + D + G G S +
Sbjct: 458 EKPYSCGECGKGFSCSSHLSSHQKTHTGERPYQCD--------KCGKGFSHNSYLQAHQR 509
Query: 688 TPGSSNVTEESGVGGGLS-QTGSAQEDSPHP-SSPSSSDIGEEAGRSAGVQQPALLRDRS 745
++ + + G S +G H P + G+ GRS+ + + +
Sbjct: 510 VHMGQHLYKCNVCGKSFSYSSGLLMHQRLHTGEKPYKCECGKSFGRSSDLH---IHQRVH 566
Query: 746 LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
G C CGK FR + L H R+HTGE+PY C C S+ L H H E+
Sbjct: 567 TGEKPYKCSECGKGFRRNSDLHSHQRVHTGERPYVCDVCGKGFIYSSDLLIHQRVHTGEK 626
Score = 59.7 bits (143), Expect = 2e-08
Identities = 73/285 (25%), Positives = 106/285 (37%), Gaps = 56/285 (19%)
Query: 136 GKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIH------LRTHKLGNLGKGR 189
G+ R N+ + H R G+ P++C C K L IH R +K GK
Sbjct: 327 GRGVRQNTHIRNHPRAPVGDMPYRCDVCGKGFRYKSVLLIHQGVHTGRRPYKCEECGKAF 386
Query: 190 GRVREENRLLHELEERAILRDKQLK----------GSLLQPRPDLKPPPHAQQAP--LAA 237
G R N L+H +R +K K S+LQ L H + P +
Sbjct: 387 G--RSSNLLVH---QRVHTGEKPYKCSECGKGFSYSSVLQVHQRL----HTGEKPYTCSE 437
Query: 238 CTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRILH 297
C A ++ H P KP S E GF C+ +K +R
Sbjct: 438 CGKGFCAKSALHKHQHIHPGEKPYSCGE----CGKGFSCSSHLSSHQKTHTGER------ 487
Query: 298 KPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQA 357
PY+C C S L +H ++ H+ GQ + ++C VCG+ FS +
Sbjct: 488 -PYQCDKCGKGFSHNSYLQAH-QRVHM------GQ----------HLYKCNVCGKSFSYS 529
Query: 358 WFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVK 402
L H R H + C+ CG+ F L H +VH + K
Sbjct: 530 SGLLMHQRLHTGEKPYKCE-CGKSFGRSSDLHIHQRVHTGEKPYK 573
Score = 58.5 bits (140), Expect = 4e-08
Identities = 49/181 (27%), Positives = 71/181 (39%), Gaps = 15/181 (8%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR--KGEEDGLHVGLDERRGSGSDQESQSVSR 685
EKP +C +CG+ F + +H RVH ++ K E G +G + + S R
Sbjct: 542 EKPYKC-ECGKSFGRSSDLHIHQRVHTGEKPYKCSECG--------KGFRRNSDLHSHQR 592
Query: 686 STTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDR- 744
T V + G G S + P E G+ L+ R
Sbjct: 593 VHTGERPYVCDVCGKGFIYSSDLLIHQRVHTGEKPYKC---AECGKGFSYSSGLLIHQRV 649
Query: 745 SLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRE 804
G C CGK FR + L H R+HTG+KPY C C + ++L+ H H E
Sbjct: 650 HTGEKPYRCQECGKGFRCTSSLHKHQRVHTGKKPYTCDQCGKGFSYGSNLRTHQRLHTGE 709
Query: 805 R 805
+
Sbjct: 710 K 710
Score = 55.8 bits (133), Expect = 3e-07
Identities = 31/85 (36%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 727 EEAGRSAGVQQPALLRDR-SLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCD 785
EE G++ G L+ R G C CGK F S L+VH R+HTGEKPY C C
Sbjct: 380 EECGKAFGRSSNLLVHQRVHTGEKPYKCSECGKGFSYSSVLQVHQRLHTGEKPYTCSECG 439
Query: 786 YAGTQSASLKYHLERHHRERQNGAG 810
++L H H E+ G
Sbjct: 440 KGFCAKSALHKHQHIHPGEKPYSCG 464
Score = 54.3 bits (129), Expect = 7e-07
Identities = 30/93 (32%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 716 HPSSPSSSDIGEEAGRSAGVQQPALLRDRS---LGSAMKDCPYCGKTFRTSHHLKVHLRI 772
H P+ + R GV+Q +R+ +G C CGK FR L +H +
Sbjct: 311 HQRVPTGEKSVKSLERGRGVRQNTHIRNHPRAPVGDMPYRCDVCGKGFRYKSVLLIHQGV 370
Query: 773 HTGEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
HTG +PYKC C A +S++L H H E+
Sbjct: 371 HTGRRPYKCEECGKAFGRSSNLLVHQRVHTGEK 403
Score = 53.5 bits (127), Expect = 1e-06
Identities = 46/174 (26%), Positives = 66/174 (37%), Gaps = 8/174 (4%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP C +CG+ FR + H RVH + D G + Q + +
Sbjct: 653 EKPYRCQECGKGFRCTSSLHKHQRVHTGKKPYTCDQCGKGFSYGSNLRTHQRLHTGEKPY 712
Query: 688 TPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSLG 747
T G G LS + P+ G+ +S+ +Q + G
Sbjct: 713 TCCECGKGFRYG-SGLLSHKRVHTGEKPYRCHVC----GKGYSQSSHLQGHQRVHT---G 764
Query: 748 SAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERH 801
C CGK F + L VH R+HTGEKPY C C + ++ L+ H H
Sbjct: 765 EKPYKCEECGKGFGRNSCLHVHQRVHTGEKPYTCGVCGKGFSYTSGLRNHQRVH 818
Score = 38.1 bits (87), Expect = 0.055
Identities = 15/32 (46%), Positives = 19/32 (59%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFK 159
+ Y C +CGK F + S L H R H GE P+K
Sbjct: 794 KPYTCGVCGKGFSYTSGLRNHQRVHLGENPYK 825
Score = 36.2 bits (82), Expect = 0.21
Identities = 36/187 (19%), Positives = 64/187 (34%), Gaps = 25/187 (13%)
Query: 238 CTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAA---------GFRCTFCKGKFKKREE 288
C ++ +H P++ P K ++D + + G + + F+ +
Sbjct: 223 CWISCHVDHRFPEIDKPCGCNK---CRKDCIKNSVLHRINPGENGLKSNEYRNGFRDDAD 279
Query: 289 LDRHIRILHKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANE---- 344
L H R+ K C +F+ + + T E + G G +
Sbjct: 280 LPPHPRVPLKEKLCQYDEFSEGLRHSAHLNRHQRVPTGEKSVKSLERGRGVRQNTHIRNH 339
Query: 345 ---------FRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
+RC+VCG+ F L H H + C+ CG+ F L H +VH
Sbjct: 340 PRAPVGDMPYRCDVCGKGFRYKSVLLIHQGVHTGRRPYKCEECGKAFGRSSNLLVHQRVH 399
Query: 396 LNKLSVK 402
+ K
Sbjct: 400 TGEKPYK 406
>gi|14249488 zinc finger and SCAN domain containing 10 [Homo
sapiens]
Length = 725
Score = 96.7 bits (239), Expect = 1e-19
Identities = 81/288 (28%), Positives = 104/288 (36%), Gaps = 81/288 (28%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGK 187
R + C CGK F +SIL LHMRTHT E+P C C HR Q +L HL TH
Sbjct: 319 RSFLCLCCGKSFGRSSILKLHMRTHTDERPHACHLCGHRFRQSSHLSKHLLTHS------ 372
Query: 188 GRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTLALQANHS 247
E L R R L LL D KPP C
Sbjct: 373 ------SEPAFLCAECGRGFQRRASLVQHLLAHAQDQKPP----------CA-------- 408
Query: 248 VPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRIL----------- 296
P S E P C+ C F++R L RH+RI
Sbjct: 409 ------------PESKAE--APPLTDVLCSHCGQSFQRRSSLKRHLRIHARDKDRRSSEG 454
Query: 297 ---------HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRC 347
+P+ C+ C A + E L++H + H G+ P F C
Sbjct: 455 SGSRRRDSDRRPFVCSDCGKAFRRSEHLVAH-RRVH------TGERP----------FSC 497
Query: 348 EVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
+ CG+ F+Q+ L H R H + C CG+RF L H+ H
Sbjct: 498 QACGRSFTQSSQLVSHQRVHTGEKPYACPQCGKRFVRRASLARHLLTH 545
Score = 80.5 bits (197), Expect = 1e-14
Identities = 85/357 (23%), Positives = 125/357 (35%), Gaps = 57/357 (15%)
Query: 57 EEKPPASLEEKAHVPMSGQPMGSQMALLANQLGREVDTSLNGRVDLQQFLNGQNLGIMSQ 116
++KPP + E KA P L + L S R L++ L +
Sbjct: 402 DQKPPCAPESKAEAPP-----------LTDVLCSHCGQSFQRRSSLKRHLRIHARDKDRR 450
Query: 117 MSDIEDDARKN---RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNL 173
S+ R++ R + C CGK FR + L H R HTGE+PF C C Q L
Sbjct: 451 SSEGSGSRRRDSDRRPFVCSDCGKAFRRSEHLVAHRRVHTGERPFSCQACGRSFTQSSQL 510
Query: 174 KIHLRTHKLGNLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQA 233
H R H E+ + +R + R + L P P H Q
Sbjct: 511 VSHQRVH-----------TGEKPYACPQCGKRFVRRASLARHLLTHGGPR---PHHCTQC 556
Query: 234 PLAACTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFR-------------CTFCK 280
+ A H +H P S + + +A C C
Sbjct: 557 GKSFGQTQDLARHQR---SHTGEKPCRCSECGEGFSQSAHLARHQRIHTGEKPHACDTCG 613
Query: 281 GKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGG 338
+F+ L RH R +PY C C + + L + H+ + GQ
Sbjct: 614 HRFRNSSNLARHRRSHTGERPYSCQTCGRSFRRNAHL-----RRHLATHAEPGQ------ 662
Query: 339 EQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
EQ+ C CG+ FS++ L H+ H + + C CGR F L H++ H
Sbjct: 663 EQAEPPQECVECGKSFSRSCNLLRHLLVHTGARPYSCTQCGRSFSRNSHLLRHLRTH 719
Score = 68.6 bits (166), Expect = 4e-11
Identities = 53/178 (29%), Positives = 65/178 (36%), Gaps = 10/178 (5%)
Query: 629 KPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRSTT 688
+P C DCG+ FR +V H RVH +R G Q SQ VS
Sbjct: 465 RPFVCSDCGKAFRRSEHLVAHRRVHTGERPFSCQAC--------GRSFTQSSQLVSHQRV 516
Query: 689 PGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRS-LG 747
G + S P + G+S G Q RS G
Sbjct: 517 HTGEKPYACPQCGKRFVRRASLARHLLTHGGPRPHHC-TQCGKSFGQTQDLARHQRSHTG 575
Query: 748 SAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
C CG+ F S HL H RIHTGEKP+ C C + S++L H H ER
Sbjct: 576 EKPCRCSECGEGFSQSAHLARHQRIHTGEKPHACDTCGHRFRNSSNLARHRRSHTGER 633
Score = 64.7 bits (156), Expect = 6e-10
Identities = 52/187 (27%), Positives = 72/187 (38%), Gaps = 14/187 (7%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
E+P C CGR F Q+V H RVH ++ + G + +
Sbjct: 492 ERPFSCQACGRSFTQSSQLVSHQRVHTGEKPYA--------CPQCGKRFVRRASLARHLL 543
Query: 688 TPGSSNVTEESGVGGGLSQTGS-AQEDSPHPSSPSS--SDIGEEAGRSAGVQQPALLRDR 744
T G + G QT A+ H S+ GE +SA + + +
Sbjct: 544 THGGPRPHHCTQCGKSFGQTQDLARHQRSHTGEKPCRCSECGEGFSQSAHLARHQRIHT- 602
Query: 745 SLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRE 804
G C CG FR S +L H R HTGE+PY C C + ++A L+ HL H
Sbjct: 603 --GEKPHACDTCGHRFRNSSNLARHRRSHTGERPYSCQTCGRSFRRNAHLRRHLATHAEP 660
Query: 805 RQNGAGP 811
Q A P
Sbjct: 661 GQEQAEP 667
Score = 63.2 bits (152), Expect = 2e-09
Identities = 55/177 (31%), Positives = 71/177 (40%), Gaps = 18/177 (10%)
Query: 633 CPDCGRVFRTYHQVVVHSRVHKRDRK--------GEEDGLHVGLDERRGSGSDQESQSVS 684
C +CGR F+ +V H H +D+K E L L G S Q S+
Sbjct: 379 CAECGRGFQRRASLVQHLLAHAQDQKPPCAPESKAEAPPLTDVLCSHCGQ-SFQRRSSLK 437
Query: 685 RSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDR 744
R + + S G +GS + DS S D G+ RS + R
Sbjct: 438 RHLRIHARDKDRRSSEG-----SGSRRRDSDRRPFVCS-DCGKAFRRS---EHLVAHRRV 488
Query: 745 SLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERH 801
G C CG++F S L H R+HTGEKPY CP C + ASL HL H
Sbjct: 489 HTGERPFSCQACGRSFTQSSQLVSHQRVHTGEKPYACPQCGKRFVRRASLARHLLTH 545
Score = 58.2 bits (139), Expect = 5e-08
Identities = 45/187 (24%), Positives = 74/187 (39%), Gaps = 24/187 (12%)
Query: 629 KPTECPDCGRVFRTYHQVVVHSRVHKRDR--------KGEEDGLHVGLDERRGSGSDQES 680
+P C CG+ F + H R H ++ +G H+ +R +G +
Sbjct: 549 RPHHCTQCGKSFGQTQDLARHQRSHTGEKPCRCSECGEGFSQSAHLARHQRIHTGEKPHA 608
Query: 681 QSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPAL 740
SSN+ S TG + P+ S G R+A +++
Sbjct: 609 CDTCGHRFRNSSNLARHRR-----SHTG----ERPY----SCQTCGRSFRRNAHLRRHLA 655
Query: 741 LR---DRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYH 797
+ ++C CGK+F S +L HL +HTG +PY C C + ++++ L H
Sbjct: 656 THAEPGQEQAEPPQECVECGKSFSRSCNLLRHLLVHTGARPYSCTQCGRSFSRNSHLLRH 715
Query: 798 LERHHRE 804
L H RE
Sbjct: 716 LRTHARE 722
Score = 52.8 bits (125), Expect = 2e-06
Identities = 28/94 (29%), Positives = 39/94 (41%), Gaps = 16/94 (17%)
Query: 302 CTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLK 361
C C + Q L +H ++H S F C CG+ F ++ LK
Sbjct: 294 CADCGVSFPQLSRLKAHQLRSHPAGRS----------------FLCLCCGKSFGRSSILK 337
Query: 362 GHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
HMR H D H C +CG RF++ L H+ H
Sbjct: 338 LHMRTHTDERPHACHLCGHRFRQSSHLSKHLLTH 371
Score = 51.2 bits (121), Expect = 6e-06
Identities = 42/154 (27%), Positives = 64/154 (41%), Gaps = 19/154 (12%)
Query: 669 DERRGSGSDQESQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSS--------- 719
+E +G+ + S++ +PG +G G + +G ++ S SS
Sbjct: 222 EEPKGAAWPTPILAESQADSPGVPGEPCAQSLGRGAAASGPGEDGSLLGSSEILEVKVAE 281
Query: 720 --PSSSDIGEEAGRSAGVQQPAL-------LRDRSLGSAMKDCPYCGKTFRTSHHLKVHL 770
P + + GV P L LR G + C CGK+F S LK+H+
Sbjct: 282 GVPEPNPELQFICADCGVSFPQLSRLKAHQLRSHPAGRSFL-CLCCGKSFGRSSILKLHM 340
Query: 771 RIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRE 804
R HT E+P+ C C + QS+ L HL H E
Sbjct: 341 RTHTDERPHACHLCGHRFRQSSHLSKHLLTHSSE 374
Score = 48.1 bits (113), Expect = 5e-05
Identities = 45/180 (25%), Positives = 58/180 (32%), Gaps = 32/180 (17%)
Query: 633 CPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRSTTPGSS 692
C CG+ F+ + H R+H RD+ D R GS + R
Sbjct: 423 CSHCGQSFQRRSSLKRHLRIHARDK-----------DRRSSEGSGSRRRDSDRRPFV--- 468
Query: 693 NVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEE------AGRSAGVQQPALLRDR-S 745
S G A S H + GE GRS + R
Sbjct: 469 -----------CSDCGKAFRRSEHLVAHRRVHTGERPFSCQACGRSFTQSSQLVSHQRVH 517
Query: 746 LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
G CP CGK F L HL H G +P+ C C + Q+ L H H E+
Sbjct: 518 TGEKPYACPQCGKRFVRRASLARHLLTHGGPRPHHCTQCGKSFGQTQDLARHQRSHTGEK 577
Score = 45.4 bits (106), Expect = 3e-04
Identities = 22/61 (36%), Positives = 29/61 (47%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQNGAGPL 812
C CG FR S HL HL H+ E + C C + ASL HL H ++++ P
Sbjct: 351 CHLCGHRFRQSSHLSKHLLTHSSEPAFLCAECGRGFQRRASLVQHLLAHAQDQKPPCAPE 410
Query: 813 S 813
S
Sbjct: 411 S 411
Score = 39.7 bits (91), Expect = 0.019
Identities = 36/158 (22%), Positives = 56/158 (35%), Gaps = 14/158 (8%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRK------GEEDGLHVGLDERRGSGSDQESQ 681
EKP C +CG F + H R+H ++ G L R S + +
Sbjct: 576 EKPCRCSECGEGFSQSAHLARHQRIHTGEKPHACDTCGHRFRNSSNLARHRRSHTGERPY 635
Query: 682 SVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALL 741
S N + ++ G Q + P + G+ RS + + L+
Sbjct: 636 SCQTCGRSFRRNAHLRRHLATH-AEPGQEQAEPPQ----ECVECGKSFSRSCNLLRHLLV 690
Query: 742 RDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPY 779
G+ C CG++F + HL HLR H E Y
Sbjct: 691 HT---GARPYSCTQCGRSFSRNSHLLRHLRTHARETLY 725
Score = 38.5 bits (88), Expect = 0.042
Identities = 38/163 (23%), Positives = 53/163 (32%), Gaps = 34/163 (20%)
Query: 251 VAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRILH---KPYKCTLCDF 307
VA VP P P F C C F + L H H + + C C
Sbjct: 279 VAEGVPEPNPE----------LQFICADCGVSFPQLSRLKAHQLRSHPAGRSFLCLCCGK 328
Query: 308 AASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKH 367
+ + S + K H+ + + C +CG F Q+ L H+ H
Sbjct: 329 SFGR-----SSILKLHMRTHTDE------------RPHACHLCGHRFRQSSHLSKHLLTH 371
Query: 368 KDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKNKSPSDPE 410
C CGR F+ L H+ H + K P PE
Sbjct: 372 SSEPAFLCAECGRGFQRRASLVQHLLAH----AQDQKPPCAPE 410
Score = 37.7 bits (86), Expect = 0.072
Identities = 35/137 (25%), Positives = 49/137 (35%), Gaps = 17/137 (12%)
Query: 686 STTPGSSNVTEESGVGGGLSQT--GSAQEDSPH-PSSPSSSDIGEEAGRSAGVQQPALLR 742
S TP +E G +Q DSP P P + +G A S + +LL
Sbjct: 211 SRTPDKEEFKQEEPKGAAWPTPILAESQADSPGVPGEPCAQSLGRGAAASGPGEDGSLLG 270
Query: 743 DRSLGSAMKD-------------CPYCGKTFRTSHHLKVH-LRIHTGEKPYKCPHCDYAG 788
+ C CG +F LK H LR H + + C C +
Sbjct: 271 SSEILEVKVAEGVPEPNPELQFICADCGVSFPQLSRLKAHQLRSHPAGRSFLCLCCGKSF 330
Query: 789 TQSASLKYHLERHHRER 805
+S+ LK H+ H ER
Sbjct: 331 GRSSILKLHMRTHTDER 347
Score = 32.3 bits (72), Expect = 3.0
Identities = 22/78 (28%), Positives = 31/78 (39%), Gaps = 16/78 (20%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHT-GEKP---------------YKCPHCDYAGTQSASLKY 796
C CG+ F+ L HL H +KP C HC + + +SLK
Sbjct: 379 CAECGRGFQRRASLVQHLLAHAQDQKPPCAPESKAEAPPLTDVLCSHCGQSFQRRSSLKR 438
Query: 797 HLERHHRERQNGAGPLSG 814
HL H R++ + SG
Sbjct: 439 HLRIHARDKDRRSSEGSG 456
Score = 32.3 bits (72), Expect = 3.0
Identities = 14/28 (50%), Positives = 16/28 (57%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGE 155
R Y C CG+ F NS L H+RTH E
Sbjct: 695 RPYSCTQCGRSFSRNSHLLRHLRTHARE 722
>gi|10047144 sal-like 4 [Homo sapiens]
Length = 1053
Score = 96.3 bits (238), Expect = 2e-19
Identities = 78/309 (25%), Positives = 127/309 (41%), Gaps = 55/309 (17%)
Query: 129 KYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGKG 188
K+ C C K F +S L +H+R+HTGE+PF C C HR KGNLK+H H
Sbjct: 381 KHKCKYCSKVFGTDSSLQIHLRSHTGERPFVCSVCGHRFTTKGNLKVHFHRHP------- 433
Query: 189 RGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAP-LAACTLALQAN-- 245
+V+ +L E +++ + + +L P P +P P L ++ L N
Sbjct: 434 --QVKANPQLFAEFQDK-VAAGNGIPYALSVPDPIDEPSLSLDSKPVLVTTSVGLPQNLS 490
Query: 246 ----------HSVPDVAHPVPSPK-PASVQEDAVAP------AAGFRCTFCKGKFKKREE 288
S+P P PSP+ V P A GF+ + + +
Sbjct: 491 SGTNPKDLTGGSLPGDLQPGPSPESEGGPTLPGVGPNYNSPRAGGFQGSGTPEPGSETLK 550
Query: 289 LDRHIRILHK----PYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANE 344
L + + + K P +C +C S + L H + G+ P
Sbjct: 551 LQQLVENIDKATTDPNECLICHRVLSCQSSLKMHY-------RTHTGERP---------- 593
Query: 345 FRCEVCGQVFSQAWFLKGHMRKHKDS----FEHCCQICGRRFKEPWFLKNHMKVHLNKLS 400
F+C++CG+ FS LK H+ H+ + +H C IC ++F L+ H+++H+
Sbjct: 594 FQCKICGRAFSTKGNLKTHLGVHRTNTSIKTQHSCPICQKKFTNAVMLQQHIRMHMGGQI 653
Query: 401 VKNKSPSDP 409
P +P
Sbjct: 654 PNTPLPENP 662
Score = 70.1 bits (170), Expect = 1e-11
Identities = 32/67 (47%), Positives = 38/67 (56%)
Query: 125 RKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGN 184
R+ +++ C CGK F S L +H RTHTGEKPF C C KGNLK+H TH N
Sbjct: 865 RQAKQHGCTRCGKNFSSASALQIHERTHTGEKPFVCNICGRAFTTKGNLKVHYMTHGANN 924
Query: 185 LGKGRGR 191
RGR
Sbjct: 925 NSARRGR 931
Score = 59.3 bits (142), Expect = 2e-08
Identities = 24/55 (43%), Positives = 32/55 (58%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQN 807
C YC K F T L++HLR HTGE+P+ C C + T +LK H RH + + N
Sbjct: 384 CKYCSKVFGTDSSLQIHLRSHTGERPFVCSVCGHRFTTKGNLKVHFHRHPQVKAN 438
Score = 51.2 bits (121), Expect = 6e-06
Identities = 55/228 (24%), Positives = 87/228 (38%), Gaps = 40/228 (17%)
Query: 611 GLNQTLEYNLQGPGNMKEKPTECPDCGRVFRTYHQVVVHSRVHK------------RDRK 658
G + +L+ +L+ + E+P C CG F T + VH H +D+
Sbjct: 392 GTDSSLQIHLRS--HTGERPFVCSVCGHRFTTKGNLKVHFHRHPQVKANPQLFAEFQDKV 449
Query: 659 GEEDGLHVGL---DERRGSGSDQESQSVSRSTTPG-----SSNVTEESGVGGGLS---QT 707
+G+ L D +S+ V +T+ G SS + GG L Q
Sbjct: 450 AAGNGIPYALSVPDPIDEPSLSLDSKPVLVTTSVGLPQNLSSGTNPKDLTGGSLPGDLQP 509
Query: 708 GSAQEDSPHPSSP--------------SSSDIGEEAGRSAGVQQPALLRDRSLGSAMKDC 753
G + E P+ P S E + +QQ D++ + +C
Sbjct: 510 GPSPESEGGPTLPGVGPNYNSPRAGGFQGSGTPEPGSETLKLQQLVENIDKAT-TDPNEC 568
Query: 754 PYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERH 801
C + LK+H R HTGE+P++C C A + +LK HL H
Sbjct: 569 LICHRVLSCQSSLKMHYRTHTGERPFQCKICGRAFSTKGNLKTHLGVH 616
Score = 50.8 bits (120), Expect = 8e-06
Identities = 22/49 (44%), Positives = 28/49 (57%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERH 801
C CGK F ++ L++H R HTGEKP+ C C A T +LK H H
Sbjct: 872 CTRCGKNFSSASALQIHERTHTGEKPFVCNICGRAFTTKGNLKVHYMTH 920
Score = 40.8 bits (94), Expect = 0.009
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 11/81 (13%)
Query: 325 TAESAQGQGPNGGG-------EQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQI 377
T++ +G+ PN E + + +C+ C +VF L+ H+R H C +
Sbjct: 355 TSKKGKGKPPNISAVDVKPKDEAALYKHKCKYCSKVFGTDSSLQIHLRSHTGERPFVCSV 414
Query: 378 CGRRFKEPWFLKNHMKVHLNK 398
CG RF K ++KVH ++
Sbjct: 415 CGHRFT----TKGNLKVHFHR 431
Score = 40.8 bits (94), Expect = 0.009
Identities = 80/397 (20%), Positives = 140/397 (35%), Gaps = 65/397 (16%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYK----CPHCDYAGTQSASLKYHLERHHRERQNG 808
C CG+ F T +LK HL +H K CP C T + L+ H+ R H Q
Sbjct: 596 CKICGRAFSTKGNLKTHLGVHRTNTSIKTQHSCPICQKKFTNAVMLQQHI-RMHMGGQIP 654
Query: 809 AGPLSGQPPNQDHKDEM----SSKASLFIRPDILRGAFKGLPGIDFRGGPASQQWTSGVL 864
PL P + + M + D++ + + + P+S L
Sbjct: 655 NTPLPENPCDFTGSEPMTVGENGSTGAICHDDVIESI--DVEEVSSQEAPSSSSKVPTPL 712
Query: 865 SSGDHSGQATGMSSEVPSDALKGTDLPSKSTHFSEIGRAYQSIVSNGVNFQGSLQAFMDS 924
S + G + + D P K +G A ++ G GS+++ +
Sbjct: 713 PSIHSASPTLGFA------MMASLDAPGK------VGPAPFNLQRQGSRENGSVESDGLT 760
Query: 925 FVLSSLKKEKDMKDK---------------ALADPPSMKVHGVDGGEEKPSGKSSQRKSE 969
SSL +++ + + A + S+K D G + S ++S+ + E
Sbjct: 761 NDSSSLMGDQEYQSRSPDILETTSFQALSPANSQAESIKSKSPDAGSKAESSENSRTEME 820
Query: 970 KSQYEPLDLSVRPDA---ASLPGSSV---TVQDSIA------------WHGCLFCAFTTS 1011
P P +PG+ V T+ + HGC C S
Sbjct: 821 GRSSLPSTFIRAPPTYVKVEVPGTFVGPSTLSPGMTPLLAAQPRRQAKQHGCTRCGKNFS 880
Query: 1012 SMELMALHLQANHLGKAKRKDNTIGVTVNCKD--QAREASKMALLPSLQSNKDLGLSNMI 1069
S + +H + H G+ N G K + + A S + + L + N +
Sbjct: 881 SASALQIH-ERTHTGEKPFVCNICGRAFTTKGNLKVHYMTHGANNNSARRGRKLAIENTM 939
Query: 1070 SSLDSASEKMAQGQLKETLGEQKSGAWTGHVDPAFCN 1106
+ L + +++++ KE L A + +VDP N
Sbjct: 940 ALLGTDGKRVSEIFPKEIL------APSVNVDPVVWN 970
Score = 40.0 bits (92), Expect = 0.015
Identities = 21/56 (37%), Positives = 25/56 (44%)
Query: 340 QSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
+ A + C CG+ FS A L+ H R H C ICGR F LK H H
Sbjct: 865 RQAKQHGCTRCGKNFSSASALQIHERTHTGEKPFVCNICGRAFTTKGNLKVHYMTH 920
Score = 36.2 bits (82), Expect = 0.21
Identities = 35/153 (22%), Positives = 55/153 (35%), Gaps = 21/153 (13%)
Query: 49 ELHPRPNPEEK---------PPASLEEKAHVPMSGQPMGSQMALLANQLGREVDTSLNGR 99
+L P P+PE + P + SG P L QL +D +
Sbjct: 506 DLQPGPSPESEGGPTLPGVGPNYNSPRAGGFQGSGTPEPGSETLKLQQLVENIDKATT-- 563
Query: 100 VDLQQFLNGQNLGIMSQMSDIEDDARKN---RKYPCPLCGKRFRFNSILSLHMRTHTGEK 156
D + L ++S S ++ R + R + C +CG+ F L H+ H
Sbjct: 564 -DPNECLICHR--VLSCQSSLKMHYRTHTGERPFQCKICGRAFSTKGNLKTHLGVHRTNT 620
Query: 157 PFK----CPYCDHRAAQKGNLKIHLRTHKLGNL 185
K CP C + L+ H+R H G +
Sbjct: 621 SIKTQHSCPICQKKFTNAVMLQQHIRMHMGGQI 653
>gi|110347439 zinc finger protein 225 [Homo sapiens]
Length = 706
Score = 95.1 bits (235), Expect = 4e-19
Identities = 84/327 (25%), Positives = 126/327 (38%), Gaps = 55/327 (16%)
Query: 108 GQNLGIMSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRA 167
G++ G+ S ++ ++Y C CGKRF + L H HTGEKP+ C C
Sbjct: 322 GKSFGLKSALNSHRMVHTGEKRYKCEECGKRFIYRQDLYKHQIDHTGEKPYNCKECGKSF 381
Query: 168 AQKGNLKIHLRTHKLGNLGK----GRGRVREENRLLHELE---ERAILRDKQLKGSLLQP 220
L H+R H K G+G R H+ E+ ++ KG +
Sbjct: 382 RWASGLSRHVRVHSGETTFKCEECGKGFYTNSQRYSHQRAHSGEKPYRCEECGKGYKRRL 441
Query: 221 RPDLKPPPHAQQAPL-----------AACTLALQANHSVPDVAHPVPSPKPASVQEDAVA 269
D H + P A+C L Q HS KP
Sbjct: 442 DLDFHQRVHRGEKPYNCKECGKSFGWASCLLNHQRIHS---------GEKP--------- 483
Query: 270 PAAGFRCTFCKGKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELISHVEKAHITAE 327
F+C C +F + +L H R+ KP+KC C +Q +L SH + H +
Sbjct: 484 ----FKCEECGKRFTQNSQLYTHRRVHSGEKPFKCEECGKRFTQNSQLYSH-RRVHTGVK 538
Query: 328 SAQ----GQGPNGGGEQSANE--------FRCEVCGQVFSQAWFLKGHMRKHKDSFEHCC 375
+ G+G N ++ + C+ CG+ FS+A + H R H D C
Sbjct: 539 PYKCEECGKGFNSKFNLDMHQRVHTGERPYNCKECGKSFSRASSILNHKRLHGDEKPFKC 598
Query: 376 QICGRRFKEPWFLKNHMKVHLNKLSVK 402
+ CG+RF E L +H +VH + K
Sbjct: 599 EECGKRFTENSQLHSHQRVHTGEKPYK 625
Score = 82.8 bits (203), Expect = 2e-15
Identities = 72/280 (25%), Positives = 106/280 (37%), Gaps = 47/280 (16%)
Query: 130 YPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGKGR 189
Y C +CGK F +S L +H R HTGEKPFKC C +++ L +H + H
Sbjct: 204 YNCDVCGKEFNQSSHLQIHQRIHTGEKPFKCEQCGKGFSRRSGLYVHRKLHT-------- 255
Query: 190 GRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTLALQANHSVP 249
V+ + E +A + D Q LQ + + + + +AN +
Sbjct: 256 -GVKPH---ICEKCGKAFIHDSQ-----LQEHQRIHTGEKPFKCDICCKSFRSRANLNRH 306
Query: 250 DVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRILH---KPYKCTLCD 306
+ H P FRC C F + L+ H R++H K YKC C
Sbjct: 307 SMVHMREKP---------------FRCDTCGKSFGLKSALNSH-RMVHTGEKRYKCEECG 350
Query: 307 FAASQEEELISHV-----EKAHITAES------AQGQGPNGGGEQSANEFRCEVCGQVFS 355
++L H EK + E A G + F+CE CG+ F
Sbjct: 351 KRFIYRQDLYKHQIDHTGEKPYNCKECGKSFRWASGLSRHVRVHSGETTFKCEECGKGFY 410
Query: 356 QAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
H R H + C+ CG+ +K L H +VH
Sbjct: 411 TNSQRYSHQRAHSGEKPYRCEECGKGYKRRLDLDFHQRVH 450
Score = 74.3 bits (181), Expect = 7e-13
Identities = 71/287 (24%), Positives = 104/287 (36%), Gaps = 47/287 (16%)
Query: 125 RKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH---- 180
R + Y C CGK F + S L H R H+GEKPFKC C R Q L H R H
Sbjct: 451 RGEKPYNCKECGKSFGWASCLLNHQRIHSGEKPFKCEECGKRFTQNSQLYTHRRVHSGEK 510
Query: 181 --KLGNLGKGRGRVREENRLLHELEERAILRDKQL----KGSLLQPRPDLKPPPHAQQAP 234
K GK R + ++L ++ + KG + D+ H + P
Sbjct: 511 PFKCEECGK---RFTQNSQLYSHRRVHTGVKPYKCEECGKGFNSKFNLDMHQRVHTGERP 567
Query: 235 LAA--CTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRH 292
C + S+ + KP F+C C +F + +L H
Sbjct: 568 YNCKECGKSFSRASSILNHKRLHGDEKP-------------FKCEECGKRFTENSQLHSH 614
Query: 293 IRIL--HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVC 350
R+ KPYKC C + ++H ++ H + Q CE C
Sbjct: 615 QRVHTGEKPYKCEKCGKSFRWASTHLTH-QRLHSREKLLQ----------------CEDC 657
Query: 351 GQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLN 397
G+ + LK R C+ CG+R+K L + + LN
Sbjct: 658 GKSIVHSSCLKDQQRDQSGEKTSKCEDCGKRYKRRLNLDTLLSLFLN 704
Score = 63.9 bits (154), Expect = 9e-10
Identities = 64/283 (22%), Positives = 103/283 (36%), Gaps = 51/283 (18%)
Query: 115 SQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLK 174
SQ+ + + + + C +C K FR + L+ H H EKPF+C C + LK
Sbjct: 273 SQLQEHQRIHTGEKPFKCDICCKSFRSRANLNRHSMVHMREKPFRCDTC----GKSFGLK 328
Query: 175 IHLRTHKLGNLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAP 234
L +H++ + G+ R + E +R I R K + H + P
Sbjct: 329 SALNSHRMVHTGEKRYK-------CEECGKRFIYRQDLYKHQI----------DHTGEKP 371
Query: 235 LAACTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIR 294
++ + S + F+C C F + H R
Sbjct: 372 -----------YNCKECGKSFRWASGLSRHVRVHSGETTFKCEECGKGFYTNSQRYSHQR 420
Query: 295 IL--HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQ 352
KPY+C C + +L H ++ H +G+ P + C+ CG+
Sbjct: 421 AHSGEKPYRCEECGKGYKRRLDLDFH-QRVH------RGEKP----------YNCKECGK 463
Query: 353 VFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
F A L H R H C+ CG+RF + L H +VH
Sbjct: 464 SFGWASCLLNHQRIHSGEKPFKCEECGKRFTQNSQLYTHRRVH 506
Score = 63.9 bits (154), Expect = 9e-10
Identities = 53/181 (29%), Positives = 71/181 (39%), Gaps = 14/181 (7%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVS--R 685
EKP +C +CG+ F Q+ H RVH ++ + E G Q SQ S R
Sbjct: 481 EKPFKCEECGKRFTQNSQLYTHRRVHSGEKPFK--------CEECGKRFTQNSQLYSHRR 532
Query: 686 STTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRS 745
T EE G G + P + +E G+S L R
Sbjct: 533 VHTGVKPYKCEECGKGFNSKFNLDMHQRVHTGERPYNC---KECGKSFSRASSILNHKRL 589
Query: 746 LGSAMK-DCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRE 804
G C CGK F + L H R+HTGEKPYKC C + +++ H H RE
Sbjct: 590 HGDEKPFKCEECGKRFTENSQLHSHQRVHTGEKPYKCEKCGKSFRWASTHLTHQRLHSRE 649
Query: 805 R 805
+
Sbjct: 650 K 650
Score = 63.2 bits (152), Expect = 2e-09
Identities = 65/283 (22%), Positives = 102/283 (36%), Gaps = 49/283 (17%)
Query: 135 CGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGKGRGRVRE 194
C K F S+L LH + + EK C C L+IH R H L +E
Sbjct: 153 CKKSFSDVSVLDLHQQLQSREKSHTCDECGKSFCYSSALRIHQRVHMGEKLYNCDVCGKE 212
Query: 195 ENRLLH-ELEERAILRDKQLK------------GSLLQPRPDLKPPPHAQQAPLAACTLA 241
N+ H ++ +R +K K G + + PH + C A
Sbjct: 213 FNQSSHLQIHQRIHTGEKPFKCEQCGKGFSRRSGLYVHRKLHTGVKPHICE----KCGKA 268
Query: 242 LQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRH--IRILHKP 299
+ + + KP F+C C F+ R L+RH + + KP
Sbjct: 269 FIHDSQLQEHQRIHTGEKP-------------FKCDICCKSFRSRANLNRHSMVHMREKP 315
Query: 300 YKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWF 359
++C C + + L SH H GE+ ++CE CG+ F
Sbjct: 316 FRCDTCGKSFGLKSALNSH-RMVHT-------------GEK---RYKCEECGKRFIYRQD 358
Query: 360 LKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVK 402
L H H + C+ CG+ F+ L H++VH + + K
Sbjct: 359 LYKHQIDHTGEKPYNCKECGKSFRWASGLSRHVRVHSGETTFK 401
Score = 61.6 bits (148), Expect = 5e-09
Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Query: 719 SPSSSDIGEEAGRSAGVQQPALLRDR-SLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEK 777
S S +E G+S + R +G + +C CGK F S HL++H RIHTGEK
Sbjct: 171 SREKSHTCDECGKSFCYSSALRIHQRVHMGEKLYNCDVCGKEFNQSSHLQIHQRIHTGEK 230
Query: 778 PYKCPHCDYAGTQSASLKYHLERH 801
P+KC C ++ + L H + H
Sbjct: 231 PFKCEQCGKGFSRRSGLYVHRKLH 254
Score = 60.1 bits (144), Expect = 1e-08
Identities = 64/279 (22%), Positives = 98/279 (35%), Gaps = 41/279 (14%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH------K 181
+ + C CGK F S L +H + HTG KP C C L+ H R H K
Sbjct: 230 KPFKCEQCGKGFSRRSGLYVHRKLHTGVKPHICEKCGKAFIHDSQLQEHQRIHTGEKPFK 289
Query: 182 LGNLGKG-RGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTL 240
K R R + + E+ D K L+ + H +
Sbjct: 290 CDICCKSFRSRANLNRHSMVHMREKPFRCDTCGKSFGLKSALNSHRMVHTGEKRYKCEEC 349
Query: 241 ALQANHSVPDVAHPV--PSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRIL-- 296
+ + H + KP + +E C F+ L RH+R+
Sbjct: 350 GKRFIYRQDLYKHQIDHTGEKPYNCKE-------------CGKSFRWASGLSRHVRVHSG 396
Query: 297 HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQ 356
+KC C + SH ++AH G+ P +RCE CG+ + +
Sbjct: 397 ETTFKCEECGKGFYTNSQRYSH-QRAH------SGEKP----------YRCEECGKGYKR 439
Query: 357 AWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
L H R H+ + C+ CG+ F L NH ++H
Sbjct: 440 RLDLDFHQRVHRGEKPYNCKECGKSFGWASCLLNHQRIH 478
Score = 57.0 bits (136), Expect = 1e-07
Identities = 57/204 (27%), Positives = 79/204 (38%), Gaps = 26/204 (12%)
Query: 625 NMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDR--KGEEDGL--------------HVG- 667
+M+EKP C CG+ F + H VH ++ K EE G H G
Sbjct: 310 HMREKPFRCDTCGKSFGLKSALNSHRMVHTGEKRYKCEECGKRFIYRQDLYKHQIDHTGE 369
Query: 668 --LDERRGSGSDQESQSVSRSTTPGSSNVT---EESGVGGGLSQTGSAQEDSPHPSSPSS 722
+ + S + + +SR S T EE G G T S + S
Sbjct: 370 KPYNCKECGKSFRWASGLSRHVRVHSGETTFKCEECGKG---FYTNSQRYSHQRAHSGEK 426
Query: 723 SDIGEEAGRSAGVQQPALLRDR-SLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKC 781
EE G+ + R G +C CGK+F + L H RIH+GEKP+KC
Sbjct: 427 PYRCEECGKGYKRRLDLDFHQRVHRGEKPYNCKECGKSFGWASCLLNHQRIHSGEKPFKC 486
Query: 782 PHCDYAGTQSASLKYHLERHHRER 805
C TQ++ L H H E+
Sbjct: 487 EECGKRFTQNSQLYTHRRVHSGEK 510
Score = 56.2 bits (134), Expect = 2e-07
Identities = 45/184 (24%), Positives = 70/184 (38%), Gaps = 20/184 (10%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRK------GEEDGLHVGLDERRGSGSDQESQ 681
EKP +C C + FR+ + HS VH R++ G+ GL L+ R + ++
Sbjct: 285 EKPFKCDICCKSFRSRANLNRHSMVHMREKPFRCDTCGKSFGLKSALNSHRMVHTGEKRY 344
Query: 682 SVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALL 741
G + + + TG + P+ +G S V+ +
Sbjct: 345 KCEEC---GKRFIYRQDLYKHQIDHTG----EKPYNCKECGKSFRWASGLSRHVRVHS-- 395
Query: 742 RDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERH 801
G C CGK F T+ H R H+GEKPY+C C + L +H H
Sbjct: 396 -----GETTFKCEECGKGFYTNSQRYSHQRAHSGEKPYRCEECGKGYKRRLDLDFHQRVH 450
Query: 802 HRER 805
E+
Sbjct: 451 RGEK 454
Score = 50.8 bits (120), Expect = 8e-06
Identities = 30/81 (37%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Query: 727 EEAGRSAGVQQPALLRDRSLGSAMKD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHC 784
E+ G+ ++ L R L + +K C CGK F L+ H RIHTGEKP+KC C
Sbjct: 235 EQCGKGFS-RRSGLYVHRKLHTGVKPHICEKCGKAFIHDSQLQEHQRIHTGEKPFKCDIC 293
Query: 785 DYAGTQSASLKYHLERHHRER 805
+ A+L H H RE+
Sbjct: 294 CKSFRSRANLNRHSMVHMREK 314
Score = 48.1 bits (113), Expect = 5e-05
Identities = 22/53 (41%), Positives = 29/53 (54%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
C CGK+F S L++H R+H GEK Y C C QS+ L+ H H E+
Sbjct: 178 CDECGKSFCYSSALRIHQRVHMGEKLYNCDVCGKEFNQSSHLQIHQRIHTGEK 230
Score = 43.1 bits (100), Expect = 0.002
Identities = 20/53 (37%), Positives = 26/53 (49%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
C CGK F L VH ++HTG KP+ C C A + L+ H H E+
Sbjct: 234 CEQCGKGFSRRSGLYVHRKLHTGVKPHICEKCGKAFIHDSQLQEHQRIHTGEK 286
Score = 43.1 bits (100), Expect = 0.002
Identities = 40/177 (22%), Positives = 66/177 (37%), Gaps = 26/177 (14%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR--------KGEEDGLHVGLDERRGSGSDQE 679
EKP +C +CG+ F Q+ H RVH + KG ++ + +R +G
Sbjct: 509 EKPFKCEECGKRFTQNSQLYSHRRVHTGVKPYKCEECGKGFNSKFNLDMHQRVHTGERPY 568
Query: 680 SQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPA 739
+ + +S++ + G ++ P EE G+
Sbjct: 569 NCKECGKSFSRASSILNHKRLHG---------DEKPFKC--------EECGKRFTENSQL 611
Query: 740 LLRDR-SLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLK 795
R G C CGK+FR + H R+H+ EK +C C + S+ LK
Sbjct: 612 HSHQRVHTGEKPYKCEKCGKSFRWASTHLTHQRLHSREKLLQCEDCGKSIVHSSCLK 668
Score = 42.7 bits (99), Expect = 0.002
Identities = 45/182 (24%), Positives = 73/182 (40%), Gaps = 12/182 (6%)
Query: 627 KEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRS 686
+EK C +CG+ F + +H RVH ++ D V E S Q Q +
Sbjct: 172 REKSHTCDECGKSFCYSSALRIHQRVHMGEKLYNCD---VCGKEFNQSSHLQIHQRIHTG 228
Query: 687 TTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSL 746
P E+ G G ++G H I E+ G+ A + L + +
Sbjct: 229 EKPFKC---EQCGKGFS-RRSGLYVHRKLHTGV--KPHICEKCGK-AFIHDSQLQEHQRI 281
Query: 747 GSAMKD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRE 804
+ K C C K+FR+ +L H +H EKP++C C + ++L H H E
Sbjct: 282 HTGEKPFKCDICCKSFRSRANLNRHSMVHMREKPFRCDTCGKSFGLKSALNSHRMVHTGE 341
Query: 805 RQ 806
++
Sbjct: 342 KR 343
>gi|197313746 zinc finger protein 502 [Homo sapiens]
Length = 544
Score = 91.7 bits (226), Expect = 4e-18
Identities = 78/290 (26%), Positives = 110/290 (37%), Gaps = 45/290 (15%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH------K 181
+ Y C CGK FR S L+ H R HTGEKP+KC C + +L H R H K
Sbjct: 209 KPYGCEQCGKTFRCRSFLTQHQRIHTGEKPYKCNECGNSFRNHSHLTEHQRIHTGEKPYK 268
Query: 182 LGNLGKGRGRVRE--ENRLLHELEERAILRD---KQLKGSLLQPRPDLKPPPHAQQAPLA 236
GK + ++ +H E+ I + K S L + +
Sbjct: 269 CNRCGKAFNQNTHLIHHQRIHTGEKPYICSECGSSFRKHSNLTQHQRIHTGEKPHKCDEC 328
Query: 237 ACTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRIL 296
T +AN S H P ++C C F + L +H RI
Sbjct: 329 GKTFQTKANLSQHQRIHSGEKP---------------YKCKECGKAFCQSPSLIKHQRIH 373
Query: 297 --HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVF 354
KPYKC C A +Q L H ++ H G+ P ++C CG+ F
Sbjct: 374 TGEKPYKCKECGKAFTQSTPLTKH-QRIHT------GERP----------YKCSECGKAF 416
Query: 355 SQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKNK 404
Q+ L H R H + C CG+ F + L HM++H + K K
Sbjct: 417 IQSICLIRHQRSHTGEKPYKCNECGKGFNQNTCLTQHMRIHTGEKPYKCK 466
Score = 79.0 bits (193), Expect = 3e-14
Identities = 92/393 (23%), Positives = 148/393 (37%), Gaps = 61/393 (15%)
Query: 116 QMSDIEDDAR------KNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQ 169
Q +DI D ++ + + + C CGK F +S L+ H RTHTGE+P+ C C ++
Sbjct: 135 QTNDISDQSKCPTLCTQKKSWKCNECGKTFTQSSSLTQHQRTHTGERPYTCEECGKAFSR 194
Query: 170 KGNLKIHLRTH---------KLGNLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQP 220
L H R H + G + R + + R +H E+ + G+ +
Sbjct: 195 SSFLVQHQRIHTGVKPYGCEQCGKTFRCRSFLTQHQR-IHTGEKPYKCNE---CGNSFRN 250
Query: 221 RPDLKPPP--HAQQAPLAA--CTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRC 276
L H + P C A N + KP + C
Sbjct: 251 HSHLTEHQRIHTGEKPYKCNRCGKAFNQNTHLIHHQRIHTGEKP-------------YIC 297
Query: 277 TFCKGKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGP 334
+ C F+K L +H RI KP+KC C + L H ++ H G+ P
Sbjct: 298 SECGSSFRKHSNLTQHQRIHTGEKPHKCDECGKTFQTKANLSQH-QRIH------SGEKP 350
Query: 335 NGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKV 394
++C+ CG+ F Q+ L H R H + C+ CG+ F + L H ++
Sbjct: 351 ----------YKCKECGKAFCQSPSLIKHQRIHTGEKPYKCKECGKAFTQSTPLTKHQRI 400
Query: 395 HLNKLSVKNKSPSDPEVPVPMGGMSQEAHANLYSRYLSCLQSGFMTPDKAGLSEPSQLYG 454
H + K + Q +H + C + G L++ +++
Sbjct: 401 HTGERPYKCSECGKAFIQSICLIRHQRSHTG--EKPYKCNECGKGFNQNTCLTQHMRIH- 457
Query: 455 KGELPMKEKEALGKLLSPISSMA--HGVPEGDK 485
GE P K KE GK + SS+ H G+K
Sbjct: 458 TGEKPYKCKEC-GKAFAHSSSLTEHHRTHTGEK 489
Score = 77.0 bits (188), Expect = 1e-13
Identities = 56/186 (30%), Positives = 75/186 (40%), Gaps = 24/186 (12%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR--------KGEEDGLHVGLDERRGSGSDQE 679
EKP +C +CG FR + + H R+H ++ K H+ +R +G
Sbjct: 236 EKPYKCNECGNSFRNHSHLTEHQRIHTGEKPYKCNRCGKAFNQNTHLIHHQRIHTGEKPY 295
Query: 680 SQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPA 739
S S+ SN+T+ + G + PH + G+ A + Q
Sbjct: 296 ICSECGSSFRKHSNLTQHQRIHTG---------EKPH----KCDECGKTFQTKANLSQHQ 342
Query: 740 LLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLE 799
+ G C CGK F S L H RIHTGEKPYKC C A TQS L H
Sbjct: 343 RIHS---GEKPYKCKECGKAFCQSPSLIKHQRIHTGEKPYKCKECGKAFTQSTPLTKHQR 399
Query: 800 RHHRER 805
H ER
Sbjct: 400 IHTGER 405
Score = 75.9 bits (185), Expect = 2e-13
Identities = 72/279 (25%), Positives = 105/279 (37%), Gaps = 41/279 (14%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH------K 181
+ Y C CG FR +S L+ H R HTGEKP KC C K NL H R H K
Sbjct: 293 KPYICSECGSSFRKHSNLTQHQRIHTGEKPHKCDECGKTFQTKANLSQHQRIHSGEKPYK 352
Query: 182 LGNLGKG--RGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPP-HAQQAPLAAC 238
GK + +++ +H E+ + K+ + Q P K H + P
Sbjct: 353 CKECGKAFCQSPSLIKHQRIHTGEKP--YKCKECGKAFTQSTPLTKHQRIHTGERPYKCS 410
Query: 239 TLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRIL-- 296
S+ + H + + ++C C F + L +H+RI
Sbjct: 411 ECGKAFIQSICLIRH-----------QRSHTGEKPYKCNECGKGFNQNTCLTQHMRIHTG 459
Query: 297 HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQ 356
KPYKC C A + L H + H GE+ ++C C + F +
Sbjct: 460 EKPYKCKECGKAFAHSSSLTEH-HRTHT-------------GEKL---YKCSECEKTFRK 502
Query: 357 AWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
L H R H + C CG+ F+ L H K+H
Sbjct: 503 YAHLSEHYRIHTGEKPYECIECGKFFRHSSVLFRHQKLH 541
Score = 67.0 bits (162), Expect = 1e-10
Identities = 57/199 (28%), Positives = 82/199 (41%), Gaps = 22/199 (11%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVH--KRDRKGEEDG------LHVGLDERRGSGSDQE 679
EKP C +CG FR + + H R+H ++ K +E G ++ +R SG
Sbjct: 292 EKPYICSECGSSFRKHSNLTQHQRIHTGEKPHKCDECGKTFQTKANLSQHQRIHSGEKPY 351
Query: 680 SQSVSRSTTPGSSNVTEESGVGGG-----LSQTGSAQEDSPHPSSPSSSDIGE------E 728
S ++ + + G + G A S + GE E
Sbjct: 352 KCKECGKAFCQSPSLIKHQRIHTGEKPYKCKECGKAFTQSTPLTKHQRIHTGERPYKCSE 411
Query: 729 AGRSAGVQQPALLRDRSLGSAMKD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDY 786
G+ A +Q L+R + + K C CGK F + L H+RIHTGEKPYKC C
Sbjct: 412 CGK-AFIQSICLIRHQRSHTGEKPYKCNECGKGFNQNTCLTQHMRIHTGEKPYKCKECGK 470
Query: 787 AGTQSASLKYHLERHHRER 805
A S+SL H H E+
Sbjct: 471 AFAHSSSLTEHHRTHTGEK 489
Score = 63.5 bits (153), Expect = 1e-09
Identities = 53/198 (26%), Positives = 73/198 (36%), Gaps = 20/198 (10%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRK------GEEDGLHVGLDE--RRGSGSDQE 679
EKP +C CG+ F ++ H R+H ++ G H L + R +G
Sbjct: 264 EKPYKCNRCGKAFNQNTHLIHHQRIHTGEKPYICSECGSSFRKHSNLTQHQRIHTGEKPH 323
Query: 680 SQSVSRSTTPGSSNVTEESGVGGG-----LSQTGSAQEDSPHPSSPSSSDIGE------E 728
T +N+++ + G + G A SP GE E
Sbjct: 324 KCDECGKTFQTKANLSQHQRIHSGEKPYKCKECGKAFCQSPSLIKHQRIHTGEKPYKCKE 383
Query: 729 AGRSAGVQQPALLRDR-SLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYA 787
G++ P R G C CGK F S L H R HTGEKPYKC C
Sbjct: 384 CGKAFTQSTPLTKHQRIHTGERPYKCSECGKAFIQSICLIRHQRSHTGEKPYKCNECGKG 443
Query: 788 GTQSASLKYHLERHHRER 805
Q+ L H+ H E+
Sbjct: 444 FNQNTCLTQHMRIHTGEK 461
Score = 57.8 bits (138), Expect = 7e-08
Identities = 47/176 (26%), Positives = 67/176 (38%), Gaps = 12/176 (6%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP +C +CG+ F + H R+H +R + G Q +
Sbjct: 376 EKPYKCKECGKAFTQSTPLTKHQRIHTGERPYK--------CSECGKAFIQSICLIRHQR 427
Query: 688 TPGSSNVTEESGVGGGLSQ-TGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRS- 745
+ + + G G +Q T Q H +E G++ R+
Sbjct: 428 SHTGEKPYKCNECGKGFNQNTCLTQHMRIHTGEKPYKC--KECGKAFAHSSSLTEHHRTH 485
Query: 746 LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERH 801
G + C C KTFR HL H RIHTGEKPY+C C S+ L H + H
Sbjct: 486 TGEKLYKCSECEKTFRKYAHLSEHYRIHTGEKPYECIECGKFFRHSSVLFRHQKLH 541
Score = 55.8 bits (133), Expect = 3e-07
Identities = 53/198 (26%), Positives = 75/198 (37%), Gaps = 20/198 (10%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR--KGEEDGL------HVGLDERRGSGSDQE 679
EKP +C +CG+ F+T + H R+H ++ K +E G + +R +G
Sbjct: 320 EKPHKCDECGKTFQTKANLSQHQRIHSGEKPYKCKECGKAFCQSPSLIKHQRIHTGEKPY 379
Query: 680 SQSVSRSTTPGSSNVTEESGVGGG-----LSQTGSAQEDSPHPSSPSSSDIGEEAGR--- 731
S+ +T+ + G S+ G A S S GE+ +
Sbjct: 380 KCKECGKAFTQSTPLTKHQRIHTGERPYKCSECGKAFIQSICLIRHQRSHTGEKPYKCNE 439
Query: 732 -SAGVQQPALLRDRS---LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYA 787
G Q L G C CGK F S L H R HTGEK YKC C+
Sbjct: 440 CGKGFNQNTCLTQHMRIHTGEKPYKCKECGKAFAHSSSLTEHHRTHTGEKLYKCSECEKT 499
Query: 788 GTQSASLKYHLERHHRER 805
+ A L H H E+
Sbjct: 500 FRKYAHLSEHYRIHTGEK 517
Score = 53.9 bits (128), Expect = 1e-06
Identities = 30/81 (37%), Positives = 42/81 (51%), Gaps = 3/81 (3%)
Query: 727 EEAGRSAGVQQPALLRDRSLGSAMKD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHC 784
EE G++ + L++ + + + +K C CGKTFR L H RIHTGEKPYKC C
Sbjct: 186 EECGKAFS-RSSFLVQHQRIHTGVKPYGCEQCGKTFRCRSFLTQHQRIHTGEKPYKCNEC 244
Query: 785 DYAGTQSASLKYHLERHHRER 805
+ + L H H E+
Sbjct: 245 GNSFRNHSHLTEHQRIHTGEK 265
Score = 50.1 bits (118), Expect = 1e-05
Identities = 23/49 (46%), Positives = 27/49 (55%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERH 801
C CGKTF S L H R HTGE+PY C C A ++S+ L H H
Sbjct: 157 CNECGKTFTQSSSLTQHQRTHTGERPYTCEECGKAFSRSSFLVQHQRIH 205
Score = 45.1 bits (105), Expect = 5e-04
Identities = 25/72 (34%), Positives = 27/72 (37%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQNGAGPL 812
C CGK F S L H RIHTG KPY C C + L H H E+
Sbjct: 185 CEECGKAFSRSSFLVQHQRIHTGVKPYGCEQCGKTFRCRSFLTQHQRIHTGEKPYKCNEC 244
Query: 813 SGQPPNQDHKDE 824
N H E
Sbjct: 245 GNSFRNHSHLTE 256
Score = 32.0 bits (71), Expect = 4.0
Identities = 12/28 (42%), Positives = 18/28 (64%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGE 155
+ Y C CGK FR +S+L H + H+G+
Sbjct: 517 KPYECIECGKFFRHSSVLFRHQKLHSGD 544
Score = 30.8 bits (68), Expect = 8.8
Identities = 12/29 (41%), Positives = 17/29 (58%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRD 656
EKP EC +CG+ FR + H ++H D
Sbjct: 516 EKPYECIECGKFFRHSSVLFRHQKLHSGD 544
>gi|197313744 zinc finger protein 502 [Homo sapiens]
Length = 544
Score = 91.7 bits (226), Expect = 4e-18
Identities = 78/290 (26%), Positives = 110/290 (37%), Gaps = 45/290 (15%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH------K 181
+ Y C CGK FR S L+ H R HTGEKP+KC C + +L H R H K
Sbjct: 209 KPYGCEQCGKTFRCRSFLTQHQRIHTGEKPYKCNECGNSFRNHSHLTEHQRIHTGEKPYK 268
Query: 182 LGNLGKGRGRVRE--ENRLLHELEERAILRD---KQLKGSLLQPRPDLKPPPHAQQAPLA 236
GK + ++ +H E+ I + K S L + +
Sbjct: 269 CNRCGKAFNQNTHLIHHQRIHTGEKPYICSECGSSFRKHSNLTQHQRIHTGEKPHKCDEC 328
Query: 237 ACTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRIL 296
T +AN S H P ++C C F + L +H RI
Sbjct: 329 GKTFQTKANLSQHQRIHSGEKP---------------YKCKECGKAFCQSPSLIKHQRIH 373
Query: 297 --HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVF 354
KPYKC C A +Q L H ++ H G+ P ++C CG+ F
Sbjct: 374 TGEKPYKCKECGKAFTQSTPLTKH-QRIHT------GERP----------YKCSECGKAF 416
Query: 355 SQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKNK 404
Q+ L H R H + C CG+ F + L HM++H + K K
Sbjct: 417 IQSICLIRHQRSHTGEKPYKCNECGKGFNQNTCLTQHMRIHTGEKPYKCK 466
Score = 79.0 bits (193), Expect = 3e-14
Identities = 92/393 (23%), Positives = 148/393 (37%), Gaps = 61/393 (15%)
Query: 116 QMSDIEDDAR------KNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQ 169
Q +DI D ++ + + + C CGK F +S L+ H RTHTGE+P+ C C ++
Sbjct: 135 QTNDISDQSKCPTLCTQKKSWKCNECGKTFTQSSSLTQHQRTHTGERPYTCEECGKAFSR 194
Query: 170 KGNLKIHLRTH---------KLGNLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQP 220
L H R H + G + R + + R +H E+ + G+ +
Sbjct: 195 SSFLVQHQRIHTGVKPYGCEQCGKTFRCRSFLTQHQR-IHTGEKPYKCNE---CGNSFRN 250
Query: 221 RPDLKPPP--HAQQAPLAA--CTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRC 276
L H + P C A N + KP + C
Sbjct: 251 HSHLTEHQRIHTGEKPYKCNRCGKAFNQNTHLIHHQRIHTGEKP-------------YIC 297
Query: 277 TFCKGKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGP 334
+ C F+K L +H RI KP+KC C + L H ++ H G+ P
Sbjct: 298 SECGSSFRKHSNLTQHQRIHTGEKPHKCDECGKTFQTKANLSQH-QRIH------SGEKP 350
Query: 335 NGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKV 394
++C+ CG+ F Q+ L H R H + C+ CG+ F + L H ++
Sbjct: 351 ----------YKCKECGKAFCQSPSLIKHQRIHTGEKPYKCKECGKAFTQSTPLTKHQRI 400
Query: 395 HLNKLSVKNKSPSDPEVPVPMGGMSQEAHANLYSRYLSCLQSGFMTPDKAGLSEPSQLYG 454
H + K + Q +H + C + G L++ +++
Sbjct: 401 HTGERPYKCSECGKAFIQSICLIRHQRSHTG--EKPYKCNECGKGFNQNTCLTQHMRIH- 457
Query: 455 KGELPMKEKEALGKLLSPISSMA--HGVPEGDK 485
GE P K KE GK + SS+ H G+K
Sbjct: 458 TGEKPYKCKEC-GKAFAHSSSLTEHHRTHTGEK 489
Score = 77.0 bits (188), Expect = 1e-13
Identities = 56/186 (30%), Positives = 75/186 (40%), Gaps = 24/186 (12%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR--------KGEEDGLHVGLDERRGSGSDQE 679
EKP +C +CG FR + + H R+H ++ K H+ +R +G
Sbjct: 236 EKPYKCNECGNSFRNHSHLTEHQRIHTGEKPYKCNRCGKAFNQNTHLIHHQRIHTGEKPY 295
Query: 680 SQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPA 739
S S+ SN+T+ + G + PH + G+ A + Q
Sbjct: 296 ICSECGSSFRKHSNLTQHQRIHTG---------EKPH----KCDECGKTFQTKANLSQHQ 342
Query: 740 LLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLE 799
+ G C CGK F S L H RIHTGEKPYKC C A TQS L H
Sbjct: 343 RIHS---GEKPYKCKECGKAFCQSPSLIKHQRIHTGEKPYKCKECGKAFTQSTPLTKHQR 399
Query: 800 RHHRER 805
H ER
Sbjct: 400 IHTGER 405
Score = 75.9 bits (185), Expect = 2e-13
Identities = 72/279 (25%), Positives = 105/279 (37%), Gaps = 41/279 (14%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH------K 181
+ Y C CG FR +S L+ H R HTGEKP KC C K NL H R H K
Sbjct: 293 KPYICSECGSSFRKHSNLTQHQRIHTGEKPHKCDECGKTFQTKANLSQHQRIHSGEKPYK 352
Query: 182 LGNLGKG--RGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPP-HAQQAPLAAC 238
GK + +++ +H E+ + K+ + Q P K H + P
Sbjct: 353 CKECGKAFCQSPSLIKHQRIHTGEKP--YKCKECGKAFTQSTPLTKHQRIHTGERPYKCS 410
Query: 239 TLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRIL-- 296
S+ + H + + ++C C F + L +H+RI
Sbjct: 411 ECGKAFIQSICLIRH-----------QRSHTGEKPYKCNECGKGFNQNTCLTQHMRIHTG 459
Query: 297 HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQ 356
KPYKC C A + L H + H GE+ ++C C + F +
Sbjct: 460 EKPYKCKECGKAFAHSSSLTEH-HRTHT-------------GEKL---YKCSECEKTFRK 502
Query: 357 AWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
L H R H + C CG+ F+ L H K+H
Sbjct: 503 YAHLSEHYRIHTGEKPYECIECGKFFRHSSVLFRHQKLH 541
Score = 67.0 bits (162), Expect = 1e-10
Identities = 57/199 (28%), Positives = 82/199 (41%), Gaps = 22/199 (11%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVH--KRDRKGEEDG------LHVGLDERRGSGSDQE 679
EKP C +CG FR + + H R+H ++ K +E G ++ +R SG
Sbjct: 292 EKPYICSECGSSFRKHSNLTQHQRIHTGEKPHKCDECGKTFQTKANLSQHQRIHSGEKPY 351
Query: 680 SQSVSRSTTPGSSNVTEESGVGGG-----LSQTGSAQEDSPHPSSPSSSDIGE------E 728
S ++ + + G + G A S + GE E
Sbjct: 352 KCKECGKAFCQSPSLIKHQRIHTGEKPYKCKECGKAFTQSTPLTKHQRIHTGERPYKCSE 411
Query: 729 AGRSAGVQQPALLRDRSLGSAMKD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDY 786
G+ A +Q L+R + + K C CGK F + L H+RIHTGEKPYKC C
Sbjct: 412 CGK-AFIQSICLIRHQRSHTGEKPYKCNECGKGFNQNTCLTQHMRIHTGEKPYKCKECGK 470
Query: 787 AGTQSASLKYHLERHHRER 805
A S+SL H H E+
Sbjct: 471 AFAHSSSLTEHHRTHTGEK 489
Score = 63.5 bits (153), Expect = 1e-09
Identities = 53/198 (26%), Positives = 73/198 (36%), Gaps = 20/198 (10%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRK------GEEDGLHVGLDE--RRGSGSDQE 679
EKP +C CG+ F ++ H R+H ++ G H L + R +G
Sbjct: 264 EKPYKCNRCGKAFNQNTHLIHHQRIHTGEKPYICSECGSSFRKHSNLTQHQRIHTGEKPH 323
Query: 680 SQSVSRSTTPGSSNVTEESGVGGG-----LSQTGSAQEDSPHPSSPSSSDIGE------E 728
T +N+++ + G + G A SP GE E
Sbjct: 324 KCDECGKTFQTKANLSQHQRIHSGEKPYKCKECGKAFCQSPSLIKHQRIHTGEKPYKCKE 383
Query: 729 AGRSAGVQQPALLRDR-SLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYA 787
G++ P R G C CGK F S L H R HTGEKPYKC C
Sbjct: 384 CGKAFTQSTPLTKHQRIHTGERPYKCSECGKAFIQSICLIRHQRSHTGEKPYKCNECGKG 443
Query: 788 GTQSASLKYHLERHHRER 805
Q+ L H+ H E+
Sbjct: 444 FNQNTCLTQHMRIHTGEK 461
Score = 57.8 bits (138), Expect = 7e-08
Identities = 47/176 (26%), Positives = 67/176 (38%), Gaps = 12/176 (6%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP +C +CG+ F + H R+H +R + G Q +
Sbjct: 376 EKPYKCKECGKAFTQSTPLTKHQRIHTGERPYK--------CSECGKAFIQSICLIRHQR 427
Query: 688 TPGSSNVTEESGVGGGLSQ-TGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRS- 745
+ + + G G +Q T Q H +E G++ R+
Sbjct: 428 SHTGEKPYKCNECGKGFNQNTCLTQHMRIHTGEKPYKC--KECGKAFAHSSSLTEHHRTH 485
Query: 746 LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERH 801
G + C C KTFR HL H RIHTGEKPY+C C S+ L H + H
Sbjct: 486 TGEKLYKCSECEKTFRKYAHLSEHYRIHTGEKPYECIECGKFFRHSSVLFRHQKLH 541
Score = 55.8 bits (133), Expect = 3e-07
Identities = 53/198 (26%), Positives = 75/198 (37%), Gaps = 20/198 (10%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR--KGEEDGL------HVGLDERRGSGSDQE 679
EKP +C +CG+ F+T + H R+H ++ K +E G + +R +G
Sbjct: 320 EKPHKCDECGKTFQTKANLSQHQRIHSGEKPYKCKECGKAFCQSPSLIKHQRIHTGEKPY 379
Query: 680 SQSVSRSTTPGSSNVTEESGVGGG-----LSQTGSAQEDSPHPSSPSSSDIGEEAGR--- 731
S+ +T+ + G S+ G A S S GE+ +
Sbjct: 380 KCKECGKAFTQSTPLTKHQRIHTGERPYKCSECGKAFIQSICLIRHQRSHTGEKPYKCNE 439
Query: 732 -SAGVQQPALLRDRS---LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYA 787
G Q L G C CGK F S L H R HTGEK YKC C+
Sbjct: 440 CGKGFNQNTCLTQHMRIHTGEKPYKCKECGKAFAHSSSLTEHHRTHTGEKLYKCSECEKT 499
Query: 788 GTQSASLKYHLERHHRER 805
+ A L H H E+
Sbjct: 500 FRKYAHLSEHYRIHTGEK 517
Score = 53.9 bits (128), Expect = 1e-06
Identities = 30/81 (37%), Positives = 42/81 (51%), Gaps = 3/81 (3%)
Query: 727 EEAGRSAGVQQPALLRDRSLGSAMKD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHC 784
EE G++ + L++ + + + +K C CGKTFR L H RIHTGEKPYKC C
Sbjct: 186 EECGKAFS-RSSFLVQHQRIHTGVKPYGCEQCGKTFRCRSFLTQHQRIHTGEKPYKCNEC 244
Query: 785 DYAGTQSASLKYHLERHHRER 805
+ + L H H E+
Sbjct: 245 GNSFRNHSHLTEHQRIHTGEK 265
Score = 50.1 bits (118), Expect = 1e-05
Identities = 23/49 (46%), Positives = 27/49 (55%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERH 801
C CGKTF S L H R HTGE+PY C C A ++S+ L H H
Sbjct: 157 CNECGKTFTQSSSLTQHQRTHTGERPYTCEECGKAFSRSSFLVQHQRIH 205
Score = 45.1 bits (105), Expect = 5e-04
Identities = 25/72 (34%), Positives = 27/72 (37%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQNGAGPL 812
C CGK F S L H RIHTG KPY C C + L H H E+
Sbjct: 185 CEECGKAFSRSSFLVQHQRIHTGVKPYGCEQCGKTFRCRSFLTQHQRIHTGEKPYKCNEC 244
Query: 813 SGQPPNQDHKDE 824
N H E
Sbjct: 245 GNSFRNHSHLTE 256
Score = 32.0 bits (71), Expect = 4.0
Identities = 12/28 (42%), Positives = 18/28 (64%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGE 155
+ Y C CGK FR +S+L H + H+G+
Sbjct: 517 KPYECIECGKFFRHSSVLFRHQKLHSGD 544
Score = 30.8 bits (68), Expect = 8.8
Identities = 12/29 (41%), Positives = 17/29 (58%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRD 656
EKP EC +CG+ FR + H ++H D
Sbjct: 516 EKPYECIECGKFFRHSSVLFRHQKLHSGD 544
>gi|197313742 zinc finger protein 502 [Homo sapiens]
Length = 544
Score = 91.7 bits (226), Expect = 4e-18
Identities = 78/290 (26%), Positives = 110/290 (37%), Gaps = 45/290 (15%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH------K 181
+ Y C CGK FR S L+ H R HTGEKP+KC C + +L H R H K
Sbjct: 209 KPYGCEQCGKTFRCRSFLTQHQRIHTGEKPYKCNECGNSFRNHSHLTEHQRIHTGEKPYK 268
Query: 182 LGNLGKGRGRVRE--ENRLLHELEERAILRD---KQLKGSLLQPRPDLKPPPHAQQAPLA 236
GK + ++ +H E+ I + K S L + +
Sbjct: 269 CNRCGKAFNQNTHLIHHQRIHTGEKPYICSECGSSFRKHSNLTQHQRIHTGEKPHKCDEC 328
Query: 237 ACTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRIL 296
T +AN S H P ++C C F + L +H RI
Sbjct: 329 GKTFQTKANLSQHQRIHSGEKP---------------YKCKECGKAFCQSPSLIKHQRIH 373
Query: 297 --HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVF 354
KPYKC C A +Q L H ++ H G+ P ++C CG+ F
Sbjct: 374 TGEKPYKCKECGKAFTQSTPLTKH-QRIHT------GERP----------YKCSECGKAF 416
Query: 355 SQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKNK 404
Q+ L H R H + C CG+ F + L HM++H + K K
Sbjct: 417 IQSICLIRHQRSHTGEKPYKCNECGKGFNQNTCLTQHMRIHTGEKPYKCK 466
Score = 79.0 bits (193), Expect = 3e-14
Identities = 92/393 (23%), Positives = 148/393 (37%), Gaps = 61/393 (15%)
Query: 116 QMSDIEDDAR------KNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQ 169
Q +DI D ++ + + + C CGK F +S L+ H RTHTGE+P+ C C ++
Sbjct: 135 QTNDISDQSKCPTLCTQKKSWKCNECGKTFTQSSSLTQHQRTHTGERPYTCEECGKAFSR 194
Query: 170 KGNLKIHLRTH---------KLGNLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQP 220
L H R H + G + R + + R +H E+ + G+ +
Sbjct: 195 SSFLVQHQRIHTGVKPYGCEQCGKTFRCRSFLTQHQR-IHTGEKPYKCNE---CGNSFRN 250
Query: 221 RPDLKPPP--HAQQAPLAA--CTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRC 276
L H + P C A N + KP + C
Sbjct: 251 HSHLTEHQRIHTGEKPYKCNRCGKAFNQNTHLIHHQRIHTGEKP-------------YIC 297
Query: 277 TFCKGKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGP 334
+ C F+K L +H RI KP+KC C + L H ++ H G+ P
Sbjct: 298 SECGSSFRKHSNLTQHQRIHTGEKPHKCDECGKTFQTKANLSQH-QRIH------SGEKP 350
Query: 335 NGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKV 394
++C+ CG+ F Q+ L H R H + C+ CG+ F + L H ++
Sbjct: 351 ----------YKCKECGKAFCQSPSLIKHQRIHTGEKPYKCKECGKAFTQSTPLTKHQRI 400
Query: 395 HLNKLSVKNKSPSDPEVPVPMGGMSQEAHANLYSRYLSCLQSGFMTPDKAGLSEPSQLYG 454
H + K + Q +H + C + G L++ +++
Sbjct: 401 HTGERPYKCSECGKAFIQSICLIRHQRSHTG--EKPYKCNECGKGFNQNTCLTQHMRIH- 457
Query: 455 KGELPMKEKEALGKLLSPISSMA--HGVPEGDK 485
GE P K KE GK + SS+ H G+K
Sbjct: 458 TGEKPYKCKEC-GKAFAHSSSLTEHHRTHTGEK 489
Score = 77.0 bits (188), Expect = 1e-13
Identities = 56/186 (30%), Positives = 75/186 (40%), Gaps = 24/186 (12%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR--------KGEEDGLHVGLDERRGSGSDQE 679
EKP +C +CG FR + + H R+H ++ K H+ +R +G
Sbjct: 236 EKPYKCNECGNSFRNHSHLTEHQRIHTGEKPYKCNRCGKAFNQNTHLIHHQRIHTGEKPY 295
Query: 680 SQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPA 739
S S+ SN+T+ + G + PH + G+ A + Q
Sbjct: 296 ICSECGSSFRKHSNLTQHQRIHTG---------EKPH----KCDECGKTFQTKANLSQHQ 342
Query: 740 LLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLE 799
+ G C CGK F S L H RIHTGEKPYKC C A TQS L H
Sbjct: 343 RIHS---GEKPYKCKECGKAFCQSPSLIKHQRIHTGEKPYKCKECGKAFTQSTPLTKHQR 399
Query: 800 RHHRER 805
H ER
Sbjct: 400 IHTGER 405
Score = 75.9 bits (185), Expect = 2e-13
Identities = 72/279 (25%), Positives = 105/279 (37%), Gaps = 41/279 (14%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH------K 181
+ Y C CG FR +S L+ H R HTGEKP KC C K NL H R H K
Sbjct: 293 KPYICSECGSSFRKHSNLTQHQRIHTGEKPHKCDECGKTFQTKANLSQHQRIHSGEKPYK 352
Query: 182 LGNLGKG--RGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPP-HAQQAPLAAC 238
GK + +++ +H E+ + K+ + Q P K H + P
Sbjct: 353 CKECGKAFCQSPSLIKHQRIHTGEKP--YKCKECGKAFTQSTPLTKHQRIHTGERPYKCS 410
Query: 239 TLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRIL-- 296
S+ + H + + ++C C F + L +H+RI
Sbjct: 411 ECGKAFIQSICLIRH-----------QRSHTGEKPYKCNECGKGFNQNTCLTQHMRIHTG 459
Query: 297 HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQ 356
KPYKC C A + L H + H GE+ ++C C + F +
Sbjct: 460 EKPYKCKECGKAFAHSSSLTEH-HRTHT-------------GEKL---YKCSECEKTFRK 502
Query: 357 AWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
L H R H + C CG+ F+ L H K+H
Sbjct: 503 YAHLSEHYRIHTGEKPYECIECGKFFRHSSVLFRHQKLH 541
Score = 67.0 bits (162), Expect = 1e-10
Identities = 57/199 (28%), Positives = 82/199 (41%), Gaps = 22/199 (11%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVH--KRDRKGEEDG------LHVGLDERRGSGSDQE 679
EKP C +CG FR + + H R+H ++ K +E G ++ +R SG
Sbjct: 292 EKPYICSECGSSFRKHSNLTQHQRIHTGEKPHKCDECGKTFQTKANLSQHQRIHSGEKPY 351
Query: 680 SQSVSRSTTPGSSNVTEESGVGGG-----LSQTGSAQEDSPHPSSPSSSDIGE------E 728
S ++ + + G + G A S + GE E
Sbjct: 352 KCKECGKAFCQSPSLIKHQRIHTGEKPYKCKECGKAFTQSTPLTKHQRIHTGERPYKCSE 411
Query: 729 AGRSAGVQQPALLRDRSLGSAMKD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDY 786
G+ A +Q L+R + + K C CGK F + L H+RIHTGEKPYKC C
Sbjct: 412 CGK-AFIQSICLIRHQRSHTGEKPYKCNECGKGFNQNTCLTQHMRIHTGEKPYKCKECGK 470
Query: 787 AGTQSASLKYHLERHHRER 805
A S+SL H H E+
Sbjct: 471 AFAHSSSLTEHHRTHTGEK 489
Score = 63.5 bits (153), Expect = 1e-09
Identities = 53/198 (26%), Positives = 73/198 (36%), Gaps = 20/198 (10%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRK------GEEDGLHVGLDE--RRGSGSDQE 679
EKP +C CG+ F ++ H R+H ++ G H L + R +G
Sbjct: 264 EKPYKCNRCGKAFNQNTHLIHHQRIHTGEKPYICSECGSSFRKHSNLTQHQRIHTGEKPH 323
Query: 680 SQSVSRSTTPGSSNVTEESGVGGG-----LSQTGSAQEDSPHPSSPSSSDIGE------E 728
T +N+++ + G + G A SP GE E
Sbjct: 324 KCDECGKTFQTKANLSQHQRIHSGEKPYKCKECGKAFCQSPSLIKHQRIHTGEKPYKCKE 383
Query: 729 AGRSAGVQQPALLRDR-SLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYA 787
G++ P R G C CGK F S L H R HTGEKPYKC C
Sbjct: 384 CGKAFTQSTPLTKHQRIHTGERPYKCSECGKAFIQSICLIRHQRSHTGEKPYKCNECGKG 443
Query: 788 GTQSASLKYHLERHHRER 805
Q+ L H+ H E+
Sbjct: 444 FNQNTCLTQHMRIHTGEK 461
Score = 57.8 bits (138), Expect = 7e-08
Identities = 47/176 (26%), Positives = 67/176 (38%), Gaps = 12/176 (6%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP +C +CG+ F + H R+H +R + G Q +
Sbjct: 376 EKPYKCKECGKAFTQSTPLTKHQRIHTGERPYK--------CSECGKAFIQSICLIRHQR 427
Query: 688 TPGSSNVTEESGVGGGLSQ-TGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRS- 745
+ + + G G +Q T Q H +E G++ R+
Sbjct: 428 SHTGEKPYKCNECGKGFNQNTCLTQHMRIHTGEKPYKC--KECGKAFAHSSSLTEHHRTH 485
Query: 746 LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERH 801
G + C C KTFR HL H RIHTGEKPY+C C S+ L H + H
Sbjct: 486 TGEKLYKCSECEKTFRKYAHLSEHYRIHTGEKPYECIECGKFFRHSSVLFRHQKLH 541
Score = 55.8 bits (133), Expect = 3e-07
Identities = 53/198 (26%), Positives = 75/198 (37%), Gaps = 20/198 (10%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR--KGEEDGL------HVGLDERRGSGSDQE 679
EKP +C +CG+ F+T + H R+H ++ K +E G + +R +G
Sbjct: 320 EKPHKCDECGKTFQTKANLSQHQRIHSGEKPYKCKECGKAFCQSPSLIKHQRIHTGEKPY 379
Query: 680 SQSVSRSTTPGSSNVTEESGVGGG-----LSQTGSAQEDSPHPSSPSSSDIGEEAGR--- 731
S+ +T+ + G S+ G A S S GE+ +
Sbjct: 380 KCKECGKAFTQSTPLTKHQRIHTGERPYKCSECGKAFIQSICLIRHQRSHTGEKPYKCNE 439
Query: 732 -SAGVQQPALLRDRS---LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYA 787
G Q L G C CGK F S L H R HTGEK YKC C+
Sbjct: 440 CGKGFNQNTCLTQHMRIHTGEKPYKCKECGKAFAHSSSLTEHHRTHTGEKLYKCSECEKT 499
Query: 788 GTQSASLKYHLERHHRER 805
+ A L H H E+
Sbjct: 500 FRKYAHLSEHYRIHTGEK 517
Score = 53.9 bits (128), Expect = 1e-06
Identities = 30/81 (37%), Positives = 42/81 (51%), Gaps = 3/81 (3%)
Query: 727 EEAGRSAGVQQPALLRDRSLGSAMKD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHC 784
EE G++ + L++ + + + +K C CGKTFR L H RIHTGEKPYKC C
Sbjct: 186 EECGKAFS-RSSFLVQHQRIHTGVKPYGCEQCGKTFRCRSFLTQHQRIHTGEKPYKCNEC 244
Query: 785 DYAGTQSASLKYHLERHHRER 805
+ + L H H E+
Sbjct: 245 GNSFRNHSHLTEHQRIHTGEK 265
Score = 50.1 bits (118), Expect = 1e-05
Identities = 23/49 (46%), Positives = 27/49 (55%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERH 801
C CGKTF S L H R HTGE+PY C C A ++S+ L H H
Sbjct: 157 CNECGKTFTQSSSLTQHQRTHTGERPYTCEECGKAFSRSSFLVQHQRIH 205
Score = 45.1 bits (105), Expect = 5e-04
Identities = 25/72 (34%), Positives = 27/72 (37%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQNGAGPL 812
C CGK F S L H RIHTG KPY C C + L H H E+
Sbjct: 185 CEECGKAFSRSSFLVQHQRIHTGVKPYGCEQCGKTFRCRSFLTQHQRIHTGEKPYKCNEC 244
Query: 813 SGQPPNQDHKDE 824
N H E
Sbjct: 245 GNSFRNHSHLTE 256
Score = 32.0 bits (71), Expect = 4.0
Identities = 12/28 (42%), Positives = 18/28 (64%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGE 155
+ Y C CGK FR +S+L H + H+G+
Sbjct: 517 KPYECIECGKFFRHSSVLFRHQKLHSGD 544
Score = 30.8 bits (68), Expect = 8.8
Identities = 12/29 (41%), Positives = 17/29 (58%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRD 656
EKP EC +CG+ FR + H ++H D
Sbjct: 516 EKPYECIECGKFFRHSSVLFRHQKLHSGD 544
>gi|110815807 zinc finger protein 169 [Homo sapiens]
Length = 603
Score = 90.5 bits (223), Expect = 9e-18
Identities = 80/286 (27%), Positives = 112/286 (39%), Gaps = 55/286 (19%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH------- 180
+ + CP CG+ F S L H RTHTGEKP+ CP C R +QK +L IH R H
Sbjct: 232 KHHVCPECGRGFCQRSDLIKHQRTHTGEKPYLCPECGRRFSQKASLSIHQRKHSGEKPYV 291
Query: 181 --KLGNLGKGRGRVREENRLLHELEERAILRD-----KQLKGSLLQPRPDLKPPPH-AQQ 232
+ G + + R +H E + ++ +Q LL R L+ P +
Sbjct: 292 CRECGRHFRYTSSLTNHKR-IHSGERPFVCQECGRGFRQKIALLLHQRTHLEEKPFVCPE 350
Query: 233 APLAACTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRH 292
C A H +H P F C C F+++ L H
Sbjct: 351 CGRGFCQKASLLQH---QSSHTGERP---------------FLCLECGRSFRQQSLLLSH 392
Query: 293 IRILH---KPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEV 349
++ H KPY C C + Q+ LI H ++ H G+ P + C
Sbjct: 393 -QVTHSGEKPYVCAECGHSFRQKVTLIRH-QRTH------TGEKP----------YLCPQ 434
Query: 350 CGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
CG+ FSQ L GH R H + C CGR F + L H + H
Sbjct: 435 CGRGFSQKVTLIGHQRTHTGEKPYLCPDCGRGFGQKVTLIRHQRTH 480
Score = 85.9 bits (211), Expect = 2e-16
Identities = 85/303 (28%), Positives = 116/303 (38%), Gaps = 62/303 (20%)
Query: 116 QMSDIEDDARKN---RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGN 172
Q SD+ R + + Y CP CG+RF + LS+H R H+GEKP+ C C +
Sbjct: 245 QRSDLIKHQRTHTGEKPYLCPECGRRFSQKASLSIHQRKHSGEKPYVCRECGRHFRYTSS 304
Query: 173 LKIHLRTHKLGNLGK--------GRGRVREENRLLHE---LEERAIL-----RDKQLKGS 216
L H R H G+ GRG ++ LLH+ LEE+ + R K S
Sbjct: 305 LTNHKRIHS----GERPFVCQECGRGFRQKIALLLHQRTHLEEKPFVCPECGRGFCQKAS 360
Query: 217 LLQPRPDLKPPPHAQQAPLAACTLALQANHSVPDVAHPV--PSPKPASVQEDAVAPAAGF 274
LLQ + H + P ++H V KP +
Sbjct: 361 LLQHQSS-----HTGERPFLCLECGRSFRQQSLLLSHQVTHSGEKP-------------Y 402
Query: 275 RCTFCKGKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQ 332
C C F+++ L RH R KPY C C SQ+ LI H ++ H G+
Sbjct: 403 VCAECGHSFRQKVTLIRHQRTHTGEKPYLCPQCGRGFSQKVTLIGH-QRTH------TGE 455
Query: 333 GPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHM 392
P + C CG+ F Q L H R H + C CGR F L H
Sbjct: 456 KP----------YLCPDCGRGFGQKVTLIRHQRTHTGEKPYLCPKCGRAFGFKSLLTRHQ 505
Query: 393 KVH 395
+ H
Sbjct: 506 RTH 508
Score = 71.2 bits (173), Expect = 6e-12
Identities = 80/328 (24%), Positives = 121/328 (36%), Gaps = 58/328 (17%)
Query: 115 SQMSDIEDDARKN---RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKG 171
SQ + + RK+ + Y C CG+ FR+ S L+ H R H+GE+PF C C QK
Sbjct: 272 SQKASLSIHQRKHSGEKPYVCRECGRHFRYTSSLTNHKRIHSGERPFVCQECGRGFRQKI 331
Query: 172 NLKIHLRTHKLGNLGK----GRGRVREENRLLHELE---ERAIL-----RDKQLKGSLLQ 219
L +H RTH GRG ++ + L H+ ER L R + + LL
Sbjct: 332 ALLLHQRTHLEEKPFVCPECGRGFCQKASLLQHQSSHTGERPFLCLECGRSFRQQSLLLS 391
Query: 220 PRPDLKPPPHAQQAPLAACTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAG------ 273
+ H+ + P + HS + + + ++ + P G
Sbjct: 392 HQVT-----HSGEKPYVCA----ECGHSFRQKVTLIRHQRTHTGEKPYLCPQCGRGFSQK 442
Query: 274 ---------------FRCTFCKGKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELI 316
+ C C F ++ L RH R KPY C C A + L
Sbjct: 443 VTLIGHQRTHTGEKPYLCPDCGRGFGQKVTLIRHQRTHTGEKPYLCPKCGRAFGFKSLLT 502
Query: 317 SHV-----EKAHITAESAQGQGPNGG--GEQSANEFR----CEVCGQVFSQAWFLKGHMR 365
H E+ ++ QG G +Q + C+ CG+ F L H R
Sbjct: 503 RHQRTHSEEELYVDRVCGQGLGQKSHLISDQRTHSGEKPCICDECGRGFGFKSALIRHQR 562
Query: 366 KHKDSFEHCCQICGRRFKEPWFLKNHMK 393
H + C+ CGR F + L H +
Sbjct: 563 THSGEKPYVCRECGRGFSQKSHLHRHRR 590
Score = 65.1 bits (157), Expect = 4e-10
Identities = 57/181 (31%), Positives = 71/181 (39%), Gaps = 14/181 (7%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP C +CGR FR + H R+H +R + + G G Q+ +
Sbjct: 287 EKPYVCRECGRHFRYTSSLTNHKRIHSGERPF--------VCQECGRGFRQKIALLLHQR 338
Query: 688 TPGSSNVTEESGVGGGLSQTGSA-QEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSL 746
T G G Q S Q S H + E GRS QQ LL +
Sbjct: 339 THLEEKPFVCPECGRGFCQKASLLQHQSSHTGERPFLCL--ECGRSFR-QQSLLLSHQVT 395
Query: 747 GSAMKD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRE 804
S K C CG +FR L H R HTGEKPY CP C +Q +L H H E
Sbjct: 396 HSGEKPYVCAECGHSFRQKVTLIRHQRTHTGEKPYLCPQCGRGFSQKVTLIGHQRTHTGE 455
Query: 805 R 805
+
Sbjct: 456 K 456
Score = 57.8 bits (138), Expect = 7e-08
Identities = 33/85 (38%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
Query: 723 SDIGEEAGRSAGVQQPALLRDRSLGSAMKD--CPYCGKTFRTSHHLKVHLRIHTGEKPYK 780
+D E G + L + SL S K CP CG+ F L H R HTGEKPY
Sbjct: 204 ADTSESGAVIRGNYRLGLSKKSSLFSHQKHHVCPECGRGFCQRSDLIKHQRTHTGEKPYL 263
Query: 781 CPHCDYAGTQSASLKYHLERHHRER 805
CP C +Q ASL H +H E+
Sbjct: 264 CPECGRRFSQKASLSIHQRKHSGEK 288
Score = 57.4 bits (137), Expect = 9e-08
Identities = 50/180 (27%), Positives = 71/180 (39%), Gaps = 16/180 (8%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP CP CGR F ++ H R H ++ ++ D RG G R+
Sbjct: 427 EKPYLCPQCGRGFSQKVTLIGHQRTHTGEKP------YLCPDCGRGFGQKVTLIRHQRTH 480
Query: 688 TPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSLG 747
T + + G G + + + S + G+ G Q+ L+ D+
Sbjct: 481 TGEKPYLCPKCGRAFGFKSLLTRHQRT---HSEEELYVDRVCGQGLG-QKSHLISDQRTH 536
Query: 748 SAMKDC--PYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
S K C CG+ F L H R H+GEKPY C C + S K HL RH R +
Sbjct: 537 SGEKPCICDECGRGFGFKSALIRHQRTHSGEKPYVCRECG----RGFSQKSHLHRHRRTK 592
Score = 56.6 bits (135), Expect = 2e-07
Identities = 54/197 (27%), Positives = 74/197 (37%), Gaps = 40/197 (20%)
Query: 611 GLNQTLEYNLQGPGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDE 670
G Q + L +++EKP CP+CGR F ++ H H +R L
Sbjct: 326 GFRQKIALLLHQRTHLEEKPFVCPECGRGFCQKASLLQHQSSHTGERP--------FLCL 377
Query: 671 RRGSGSDQESQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAG 730
G Q+S +S T SG + P+ + E G
Sbjct: 378 ECGRSFRQQSLLLSHQVT--------HSG-------------EKPY--------VCAECG 408
Query: 731 RSAGVQQPALLRDRSLGSAMKD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAG 788
S Q+ L+R + + K CP CG+ F L H R HTGEKPY CP C
Sbjct: 409 HSFR-QKVTLIRHQRTHTGEKPYLCPQCGRGFSQKVTLIGHQRTHTGEKPYLCPDCGRGF 467
Query: 789 TQSASLKYHLERHHRER 805
Q +L H H E+
Sbjct: 468 GQKVTLIRHQRTHTGEK 484
Score = 56.6 bits (135), Expect = 2e-07
Identities = 42/131 (32%), Positives = 55/131 (41%), Gaps = 13/131 (9%)
Query: 50 LHPRPNPEEKPPASLEEKAHVPMSGQPMGSQMALLANQLGREVDTSLNGRVDLQQFLNGQ 109
LH R + EEKP P G+ + +LL +Q +S G G+
Sbjct: 335 LHQRTHLEEKPFVC-------PECGRGFCQKASLLQHQ------SSHTGERPFLCLECGR 381
Query: 110 NLGIMSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQ 169
+ S + + + Y C CG FR L H RTHTGEKP+ CP C +Q
Sbjct: 382 SFRQQSLLLSHQVTHSGEKPYVCAECGHSFRQKVTLIRHQRTHTGEKPYLCPQCGRGFSQ 441
Query: 170 KGNLKIHLRTH 180
K L H RTH
Sbjct: 442 KVTLIGHQRTH 452
Score = 55.5 bits (132), Expect = 3e-07
Identities = 43/131 (32%), Positives = 56/131 (42%), Gaps = 17/131 (12%)
Query: 51 HPRPNPEEKPPASLEEKAHVPMSGQPMGSQMALLANQLGREVDTSLNGRVDLQQFLNGQN 110
H R + EKP P G+ G + L +Q + RV GQ
Sbjct: 476 HQRTHTGEKPYLC-------PKCGRAFGFKSLLTRHQRTHSEEELYVDRVC------GQG 522
Query: 111 LGIMSQMSDIEDDARKNRKYPCPL--CGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAA 168
LG S + I D + + PC CG+ F F S L H RTH+GEKP+ C C +
Sbjct: 523 LGQKSHL--ISDQRTHSGEKPCICDECGRGFGFKSALIRHQRTHSGEKPYVCRECGRGFS 580
Query: 169 QKGNLKIHLRT 179
QK +L H RT
Sbjct: 581 QKSHLHRHRRT 591
Score = 51.2 bits (121), Expect = 6e-06
Identities = 53/205 (25%), Positives = 73/205 (35%), Gaps = 32/205 (15%)
Query: 617 EYNLQGPGNMKEK----PTECPDCG------RVFRTYHQVVVHSRVHKRD-----RKGEE 661
++ L+ P EK TE PD R+ RT+ H+ D E
Sbjct: 128 DFQLEAPRCSSEKGESGETEGPDSSLRKRPSRISRTFFSP------HQGDPVEWVEGNRE 181
Query: 662 DGLHVGLDERRGSGSDQESQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPS 721
G + L +R G S ++ + S GLS+ S H P
Sbjct: 182 GGTDLRLAQRMSLGG---SDTMLKGADTSESGAVIRGNYRLGLSKKSSLFSHQKHHVCP- 237
Query: 722 SSDIGEEAGRSAGVQQPALLRDRS-LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYK 780
E GR + + R+ G CP CG+ F L +H R H+GEKPY
Sbjct: 238 ------ECGRGFCQRSDLIKHQRTHTGEKPYLCPECGRRFSQKASLSIHQRKHSGEKPYV 291
Query: 781 CPHCDYAGTQSASLKYHLERHHRER 805
C C ++SL H H ER
Sbjct: 292 CRECGRHFRYTSSLTNHKRIHSGER 316
Score = 50.1 bits (118), Expect = 1e-05
Identities = 37/125 (29%), Positives = 48/125 (38%), Gaps = 19/125 (15%)
Query: 276 CTFCKGKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQG 333
C C F +R +L +H R KPY C C SQ+ L H K G+
Sbjct: 236 CPECGRGFCQRSDLIKHQRTHTGEKPYLCPECGRRFSQKASLSIHQRKH-------SGEK 288
Query: 334 PNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMK 393
P + C CG+ F L H R H CQ CGR F++ L H +
Sbjct: 289 P----------YVCRECGRHFRYTSSLTNHKRIHSGERPFVCQECGRGFRQKIALLLHQR 338
Query: 394 VHLNK 398
HL +
Sbjct: 339 THLEE 343
Score = 46.2 bits (108), Expect = 2e-04
Identities = 42/152 (27%), Positives = 57/152 (37%), Gaps = 12/152 (7%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP CPDCGR F ++ H R H ++ L + G +S
Sbjct: 455 EKPYLCPDCGRGFGQKVTLIRHQRTHTGEKPY--------LCPKCGRAFGFKSLLTRHQR 506
Query: 688 TPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSLG 747
T + + G GL Q D S I +E GR G + AL+R +
Sbjct: 507 THSEEELYVDRVCGQGLGQKSHLISDQ-RTHSGEKPCICDECGRGFGFKS-ALIRHQRTH 564
Query: 748 SAMKD--CPYCGKTFRTSHHLKVHLRIHTGEK 777
S K C CG+ F HL H R +G +
Sbjct: 565 SGEKPYVCRECGRGFSQKSHLHRHRRTKSGHQ 596
>gi|46409310 zinc finger protein 467 [Homo sapiens]
Length = 595
Score = 90.5 bits (223), Expect = 9e-18
Identities = 84/318 (26%), Positives = 109/318 (34%), Gaps = 72/318 (22%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGK 187
R YPC CGKRF L H +THTGE+PF C C+ R +K +L H R H +
Sbjct: 242 RPYPCAECGKRFSQKIHLGSHQKTHTGERPFPCTECEKRFRKKTHLIRHQRIHTGERPYQ 301
Query: 188 GRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPH------------------ 229
R H + + R Q G +P PD PH
Sbjct: 302 CAQCARSFTHKQHLVRHQ---RVHQTAGP-ARPSPDSSASPHSTAPSPTPSFPGPKPFAC 357
Query: 230 ---------------------AQQAPLAACTLALQANHSVPDVAHPV------PSPKPAS 262
++ P AL A P A P+ P P S
Sbjct: 358 SDCGLSFGWKKNLATHQCLHRSEGRPFGCDECALGATVDAP-AAKPLASAPGGPGCGPGS 416
Query: 263 ---VQEDAVAPAAGFRCTFCKGKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELIS 317
V + A + F C C F + L RH R+ +P+ CT CD L++
Sbjct: 417 DPVVPQRAPSGERSFFCPDCGRGFSHGQHLARHPRVHTGERPFACTQCDRRFGSRPNLVA 476
Query: 318 HVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQI 377
H +AH A F C CG+ FS+ L H H S H C +
Sbjct: 477 H-SRAH----------------SGARPFACAQCGRRFSRKSHLGRHQAVHTGSRPHACAV 519
Query: 378 CGRRFKEPWFLKNHMKVH 395
C R F L H +H
Sbjct: 520 CARSFSSKTNLVRHQAIH 537
Score = 76.6 bits (187), Expect = 1e-13
Identities = 82/302 (27%), Positives = 113/302 (37%), Gaps = 48/302 (15%)
Query: 132 CPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH----------- 180
CP CG+ F + + LH R+H GE+PF C CD R ++K +L HLRTH
Sbjct: 190 CPDCGRSFTQRAHMLLHQRSHRGERPFPCSECDKRFSKKAHLTRHLRTHTGERPYPCAEC 249
Query: 181 ------KLGNLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAP 234
K+ + E E E+R + ++ + +P AQ A
Sbjct: 250 GKRFSQKIHLGSHQKTHTGERPFPCTECEKRFRKKTHLIRHQRIHTGE--RPYQCAQCAR 307
Query: 235 LAACTLALQANHSVPDVAHPV-PSP-KPASVQEDAVAPAAG------FRCTFCKGKFKKR 286
L + V A P PSP AS A +P F C+ C F +
Sbjct: 308 SFTHKQHLVRHQRVHQTAGPARPSPDSSASPHSTAPSPTPSFPGPKPFACSDCGLSFGWK 367
Query: 287 EELDRHIRILH----KPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNG------ 336
+ L H + LH +P+ C C A+ + + K +A G GP
Sbjct: 368 KNLATH-QCLHRSEGRPFGCDECALGATVD----APAAKPLASAPGGPGCGPGSDPVVPQ 422
Query: 337 ---GGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMK 393
GE+S F C CG+ FS L H R H C C RRF L H +
Sbjct: 423 RAPSGERS---FFCPDCGRGFSHGQHLARHPRVHTGERPFACTQCDRRFGSRPNLVAHSR 479
Query: 394 VH 395
H
Sbjct: 480 AH 481
Score = 73.9 bits (180), Expect = 9e-13
Identities = 92/411 (22%), Positives = 144/411 (35%), Gaps = 83/411 (20%)
Query: 3 EASLCLGVSSAEPEAEPHLSGPVLNGQYAMSQKLHQITSQLSHAFPELHPRPNPEEKPPA 62
EA LG S +PE P S P G + +++ + + H P PEE
Sbjct: 6 EALSSLGFSVGQPEMAPQ-SEP-REGSHNAQEQMSSSREERALGVCSGHEAPTPEE---G 60
Query: 63 SLEEKAHVPMSGQPMGSQMA-----------LLANQLGREVDTSLNGRVDLQQFLN---- 107
+ E+A P GQ +Q A ++ + D V+ Q L+
Sbjct: 61 AHTEQAEAPCRGQACSAQKAQPVGTCPGEEWMIRKVKVEDEDQEAEEEVEWPQHLSLLPS 120
Query: 108 ---GQNLGIMSQMSDIEDDA--------------RKNRKYPCPLCGKRFRFNSILSLHMR 150
+LG ++ +E A + Y C C +RFR L LH R
Sbjct: 121 PFPAPDLGHLAAAYKLEPGAPGALSGLALSGWGPMPEKPYGCGECERRFRDQLTLRLHQR 180
Query: 151 THTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGKGRGRVREENRLLHELEERAILRD 210
H GE P CP C Q+ ++ +H R+H+ E E ++R
Sbjct: 181 LHRGEGPCACPDCGRSFTQRAHMLLHQRSHR-----------GERPFPCSECDKR--FSK 227
Query: 211 KQLKGSLLQPRPDLKPPPHAQQAPLAACTLALQANHSVPDVAHPVPSPKPASVQEDAVAP 270
K L+ +P P A+ + + L ++ P P
Sbjct: 228 KAHLTRHLRTHTGERPYPCAECGKRFSQKIHLGSHQKTHTGERPFP-------------- 273
Query: 271 AAGFRCTFCKGKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELISHVEKAHITAES 328
CT C+ +F+K+ L RH RI +PY+C C + + ++ L+ H ++ H TA
Sbjct: 274 -----CTECEKRFRKKTHLIRHQRIHTGERPYQCAQCARSFTHKQHLVRH-QRVHQTAGP 327
Query: 329 AQGQGPNGGGEQSA-----------NEFRCEVCGQVFSQAWFLKGHMRKHK 368
A+ + S F C CG F L H H+
Sbjct: 328 ARPSPDSSASPHSTAPSPTPSFPGPKPFACSDCGLSFGWKKNLATHQCLHR 378
Score = 65.1 bits (157), Expect = 4e-10
Identities = 57/205 (27%), Positives = 79/205 (38%), Gaps = 29/205 (14%)
Query: 620 LQGPGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDR--------KGEEDGLHVGLDER 671
L G G M EKP C +C R FR + +H R+H+ + + H+ L +R
Sbjct: 149 LSGWGPMPEKPYGCGECERRFRDQLTLRLHQRLHRGEGPCACPDCGRSFTQRAHMLLHQR 208
Query: 672 RGSGSDQESQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGR 731
G S +++T G + P+P + ++
Sbjct: 209 SHRGERPFPCSECDKRFSKKAHLTRHLRTHTG---------ERPYPCAECGKRFSQKI-- 257
Query: 732 SAGVQQPALLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQS 791
G Q +R C C K FR HL H RIHTGE+PY+C C +S
Sbjct: 258 HLGSHQKTHTGERPF-----PCTECEKRFRKKTHLIRHQRIHTGERPYQCAQC----ARS 308
Query: 792 ASLKYHLERHHRERQNGAGPLSGQP 816
+ K HL RH R Q AGP P
Sbjct: 309 FTHKQHLVRHQRVHQT-AGPARPSP 332
Score = 55.5 bits (132), Expect = 3e-07
Identities = 53/207 (25%), Positives = 67/207 (32%), Gaps = 47/207 (22%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
E+P +C C R F +V H RVH+ R S S + S
Sbjct: 297 ERPYQCAQCARSFTHKQHLVRHQRVHQTAGPA-----------RPSPDSSASPHSTAPSP 345
Query: 688 TPGSSN----VTEESGVGGG-------------------------LSQTGSAQEDSPHPS 718
TP + G+ G L T A P S
Sbjct: 346 TPSFPGPKPFACSDCGLSFGWKKNLATHQCLHRSEGRPFGCDECALGATVDAPAAKPLAS 405
Query: 719 SPSSSDIGEEAGRSAGVQQPALLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKP 778
+P G G V Q A +RS CP CG+ F HL H R+HTGE+P
Sbjct: 406 APGGPGCGP--GSDPVVPQRAPSGERSFF-----CPDCGRGFSHGQHLARHPRVHTGERP 458
Query: 779 YKCPHCDYAGTQSASLKYHLERHHRER 805
+ C CD +L H H R
Sbjct: 459 FACTQCDRRFGSRPNLVAHSRAHSGAR 485
Score = 51.6 bits (122), Expect = 5e-06
Identities = 47/174 (27%), Positives = 61/174 (35%), Gaps = 40/174 (22%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
E+ CPDCGR F + H RVH GE D R GS
Sbjct: 428 ERSFFCPDCGRGFSHGQHLARHPRVHT----GERPFACTQCDRRFGS------------- 470
Query: 688 TPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSLG 747
N+ S G AQ G R + + + + G
Sbjct: 471 ---RPNLVAHSRAHSGARPFACAQ-------------CGRRFSRKSHLGRHQAVHT---G 511
Query: 748 SAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERH 801
S C C ++F + +L H IHTG +P+ CP C +S S K HL RH
Sbjct: 512 SRPHACAVCARSFSSKTNLVRHQAIHTGSRPFSCPQCG----KSFSRKTHLVRH 561
Score = 49.7 bits (117), Expect = 2e-05
Identities = 35/129 (27%), Positives = 57/129 (44%), Gaps = 21/129 (16%)
Query: 270 PAAGFRCTFCKGKFKKREELDRHIRILHK---PYKCTLCDFAASQEEELISHVEKAHITA 326
P + C C+ +F+ + L H R LH+ P C C + +Q ++ H +++H
Sbjct: 156 PEKPYGCGECERRFRDQLTLRLHQR-LHRGEGPCACPDCGRSFTQRAHMLLH-QRSH--- 210
Query: 327 ESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPW 386
+G+ P F C C + FS+ L H+R H + C CG+RF +
Sbjct: 211 ---RGERP----------FPCSECDKRFSKKAHLTRHLRTHTGERPYPCAECGKRFSQKI 257
Query: 387 FLKNHMKVH 395
L +H K H
Sbjct: 258 HLGSHQKTH 266
Score = 47.8 bits (112), Expect = 7e-05
Identities = 52/203 (25%), Positives = 72/203 (35%), Gaps = 29/203 (14%)
Query: 629 KPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDE-RRGSGSDQESQSVSRST 687
KP C DCG F + H +H+ +G G DE G+ D + S
Sbjct: 353 KPFACSDCGLSFGWKKNLATHQCLHR------SEGRPFGCDECALGATVDAPAAKPLASA 406
Query: 688 T------PGSSNVTEESGVGGGLS----QTGSAQEDSPHPSSPSSSDIGE------EAGR 731
PGS V + G S G H + GE + R
Sbjct: 407 PGGPGCGPGSDPVVPQRAPSGERSFFCPDCGRGFSHGQHLARHPRVHTGERPFACTQCDR 466
Query: 732 SAGVQQPALLRDRSLGSAMK-DCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQ 790
G + + R+ A C CG+ F HL H +HTG +P+ C C +
Sbjct: 467 RFGSRPNLVAHSRAHSGARPFACAQCGRRFSRKSHLGRHQAVHTGSRPHACAVC----AR 522
Query: 791 SASLKYHLERHHRERQNGAGPLS 813
S S K +L R H+ G+ P S
Sbjct: 523 SFSSKTNLVR-HQAIHTGSRPFS 544
Score = 47.8 bits (112), Expect = 7e-05
Identities = 31/108 (28%), Positives = 43/108 (39%), Gaps = 7/108 (6%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNL----KIHLRTHKLG 183
R + C CG+RF S L H HTG +P C C + K NL IH +
Sbjct: 485 RPFACAQCGRRFSRKSHLGRHQAVHTGSRPHACAVCARSFSSKTNLVRHQAIHTGSRPFS 544
Query: 184 NLGKGRGRVREENRLLHEL---EERAILRDKQLKGSLLQPRPDLKPPP 228
G+ R+ + + H+L E D L P++ PPP
Sbjct: 545 CPQCGKSFSRKTHLVRHQLIHGEAAHAAPDAALAAPAWSAPPEVAPPP 592
Score = 43.5 bits (101), Expect = 0.001
Identities = 18/54 (33%), Positives = 27/54 (50%)
Query: 127 NRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
+R + C +C + F + L H HTG +PF CP C ++K +L H H
Sbjct: 512 SRPHACAVCARSFSSKTNLVRHQAIHTGSRPFSCPQCGKSFSRKTHLVRHQLIH 565
Score = 40.4 bits (93), Expect = 0.011
Identities = 58/248 (23%), Positives = 87/248 (35%), Gaps = 37/248 (14%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGE-KPFKCPYCDHRAAQKGNLKIHLRTHKLG-NL 185
+ + C CG F + L+ H H E +PF C C A L + G
Sbjct: 353 KPFACSDCGLSFGWKKNLATHQCLHRSEGRPFGCDECALGATVDAPAAKPLASAPGGPGC 412
Query: 186 GKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTLALQAN 245
G G V + ER+ +G P H + P A CT +
Sbjct: 413 GPGSDPVVPQRA---PSGERSFFCPDCGRGFSHGQHLARHPRVHTGERPFA-CTQCDRRF 468
Query: 246 HSVPD-VAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRH--IRILHKPYKC 302
S P+ VAH A + A F C C +F ++ L RH + +P+ C
Sbjct: 469 GSRPNLVAH-----------SRAHSGARPFACAQCGRRFSRKSHLGRHQAVHTGSRPHAC 517
Query: 303 TLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKG 362
+C + S + L+ H Q + G + F C CG+ FS+ L
Sbjct: 518 AVCARSFSSKTNLVRH-------------QAIHTG----SRPFSCPQCGKSFSRKTHLVR 560
Query: 363 HMRKHKDS 370
H H ++
Sbjct: 561 HQLIHGEA 568
Score = 38.9 bits (89), Expect = 0.032
Identities = 37/166 (22%), Positives = 59/166 (35%), Gaps = 30/166 (18%)
Query: 253 HPVPSPKPASVQEDAVAPAAGFRCTFCK----GKFKKREELDRHIRILHKPYKCTLCDFA 308
H P+P+ + E A AP G C+ K G E + R +++ + D
Sbjct: 52 HEAPTPEEGAHTEQAEAPCRGQACSAQKAQPVGTCPGEEWMIRKVKVEDE-------DQE 104
Query: 309 ASQEEELISHV----------EKAHITAE---------SAQGQGPNGGGEQSANEFRCEV 349
A +E E H+ + H+ A + G +G G + C
Sbjct: 105 AEEEVEWPQHLSLLPSPFPAPDLGHLAAAYKLEPGAPGALSGLALSGWGPMPEKPYGCGE 164
Query: 350 CGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
C + F L+ H R H+ C CGR F + + H + H
Sbjct: 165 CERRFRDQLTLRLHQRLHRGEGPCACPDCGRSFTQRAHMLLHQRSH 210
>gi|4508035 zinc finger protein 7 [Homo sapiens]
Length = 686
Score = 90.1 bits (222), Expect = 1e-17
Identities = 80/293 (27%), Positives = 120/293 (40%), Gaps = 34/293 (11%)
Query: 108 GQNLGIMSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRA 167
G+ + SQ++ + + + C CGK FR +S L H R HTGEKP++C C
Sbjct: 256 GKVFRLCSQLNQHQRIHTGEKPFKCTECGKAFRLSSKLIQHQRIHTGEKPYRCEECGKAF 315
Query: 168 AQKGNLKIHLRTHKLGNLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPP 227
Q +L H R H G+ RE + + + + + + G RP P
Sbjct: 316 GQSSSLIHHQRIHT----GERPYGCRECGKAFSQ-QSQLVRHQRTHTGE----RP--YPC 364
Query: 228 PHAQQAPLAACTLAL-QANHSVPDVAHPVPSPKPASVQEDAV-APAAGFRCTFCKGKFKK 285
+A + TLA Q H+ S P+ V + A F+C C F+
Sbjct: 365 KECGKAFSQSSTLAQHQRMHTGEKAQILKASDSPSLVAHQRIHAVEKPFKCDECGKAFRW 424
Query: 286 REELDRHIRILH---KPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSA 342
L +H +++H KPYKC C A LI H ++ H G+ P
Sbjct: 425 ISRLSQH-QLIHTGEKPYKCNKCTKAFGCSSRLIRH-QRTHT------GEKP-------- 468
Query: 343 NEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
F+C+ CG+ F Q L H R H + C CG+ F + L H ++H
Sbjct: 469 --FKCDECGKGFVQGSHLIQHQRIHTGEKPYVCNDCGKAFSQSSSLIYHQRIH 519
Score = 82.0 bits (201), Expect = 3e-15
Identities = 76/294 (25%), Positives = 114/294 (38%), Gaps = 44/294 (14%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH------K 181
+ + C CGK FR+ S LS H HTGEKP+KC C L H RTH K
Sbjct: 411 KPFKCDECGKAFRWISRLSQHQLIHTGEKPYKCNKCTKAFGCSSRLIRHQRTHTGEKPFK 470
Query: 182 LGNLGKG--RGRVREENRLLHELEERAILRD-----KQLKGSLLQPRPDLKPPPHAQQAP 234
GKG +G +++ +H E+ + D Q + R P+
Sbjct: 471 CDECGKGFVQGSHLIQHQRIHTGEKPYVCNDCGKAFSQSSSLIYHQRIHKGEKPYECLQC 530
Query: 235 LAACTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIR 294
A +++ Q ++ H P ++C C F + L +H +
Sbjct: 531 GKAFSMSTQL--TIHQRVHTGERP---------------YKCNECGKAFSQNSTLFQH-Q 572
Query: 295 ILH---KPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANE------- 344
I+H KPY+C+ C A S+ LI H ++ H A+ G G +
Sbjct: 573 IIHAGVKPYECSECGKAFSRSSYLIEH-QRIHTRAQWFYEYGNALEGSTFVSRKKVNTIK 631
Query: 345 --FRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHL 396
+CE C ++F L H R H + C CG+ F L H K+H+
Sbjct: 632 KLHQCEDCEKIFRWRSHLIIHQRIHTGEKPYKCNDCGKAFNRSSRLTQHQKIHM 685
Score = 75.9 bits (185), Expect = 2e-13
Identities = 109/480 (22%), Positives = 171/480 (35%), Gaps = 42/480 (8%)
Query: 332 QGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNH 391
QG + + C CG+VF L H R H C CG+ F+ L H
Sbjct: 237 QGKHTNNCHGEKPYECAECGKVFRLCSQLNQHQRIHTGEKPFKCTECGKAFRLSSKLIQH 296
Query: 392 MKVHLNKLSVKNKSPSDPEVPVPMGGMSQEAH---ANLYSRYLSCLQSGFMTPDKAGLSE 448
++H + + + E G S H + R C + G ++ L
Sbjct: 297 QRIHTGEKPYRCE-----ECGKAFGQSSSLIHHQRIHTGERPYGCRECGKAFSQQSQLVR 351
Query: 449 PSQLYGKGELPMKEKEALGKLLSPISSMAHG--VPEGDKHSLLGCLNLVPPLKSSCIERL 506
+ + GE P KE GK S S++A + G+K +L + P L + +R+
Sbjct: 352 HQRTH-TGERPYPCKEC-GKAFSQSSTLAQHQRMHTGEKAQILKASDS-PSLVAH--QRI 406
Query: 507 QAAAKAAEMDPVNSYQAWQLMARGMAMEHGFLSKEHPLQRNHEDTLANAGVLFDKEKREY 566
A K + D W + H + E P + N + +R +
Sbjct: 407 HAVEKPFKCDECGKAFRWISRLSQHQLIH---TGEKPYKCNKCTKAFGCSSRLIRHQRTH 463
Query: 567 VLVGADGSK----QKMPADLVHSTKVGSQRDLPSKLDPLESSRDFLSHGLNQTLEYNLQG 622
G K + V + + + + + P + + + +L Y+ +
Sbjct: 464 T-----GEKPFKCDECGKGFVQGSHLIQHQRIHTGEKPYVCNDCGKAFSQSSSLIYHQRI 518
Query: 623 PGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQS 682
+ EKP EC CG+ F Q+ +H RVH +R + + G Q S
Sbjct: 519 --HKGEKPYECLQCGKAFSMSTQLTIHQRVHTGERPYKCNEC--------GKAFSQNSTL 568
Query: 683 VSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSP-HPSSPSSSDIGEEAGRSAGVQQPALL 741
E S G S++ E H + + G S V + +
Sbjct: 569 FQHQIIHAGVKPYECSECGKAFSRSSYLIEHQRIHTRAQWFYEYGNALEGSTFVSRKKVN 628
Query: 742 RDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERH 801
+ L C C K FR HL +H RIHTGEKPYKC C A +S+ L H + H
Sbjct: 629 TIKKL----HQCEDCEKIFRWRSHLIIHQRIHTGEKPYKCNDCGKAFNRSSRLTQHQKIH 684
Score = 72.4 bits (176), Expect = 3e-12
Identities = 61/203 (30%), Positives = 83/203 (40%), Gaps = 35/203 (17%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR--KGEEDG--------------LHVGLDER 671
EKP +C +CG+ FR +++ H R+H ++ + EE G +H G ER
Sbjct: 275 EKPFKCTECGKAFRLSSKLIQHQRIHTGEKPYRCEECGKAFGQSSSLIHHQRIHTG--ER 332
Query: 672 R------GSGSDQESQSVSRSTTPGSSNVTEESGVGGGLSQTGS-AQEDSPHPSSPSSSD 724
G Q+SQ V T G SQ+ + AQ H
Sbjct: 333 PYGCRECGKAFSQQSQLVRHQRTHTGERPYPCKECGKAFSQSSTLAQHQRMHT------- 385
Query: 725 IGEEAGRSAGVQQPALLRDRSLGSAMKD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCP 782
GE+A P+L+ + + + K C CGK FR L H IHTGEKPYKC
Sbjct: 386 -GEKAQILKASDSPSLVAHQRIHAVEKPFKCDECGKAFRWISRLSQHQLIHTGEKPYKCN 444
Query: 783 HCDYAGTQSASLKYHLERHHRER 805
C A S+ L H H E+
Sbjct: 445 KCTKAFGCSSRLIRHQRTHTGEK 467
Score = 65.5 bits (158), Expect = 3e-10
Identities = 54/193 (27%), Positives = 77/193 (39%), Gaps = 15/193 (7%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRK------GEEDGLHVGLDERRGSGSDQESQ 681
E+P C +CG+ F Q+V H R H +R G+ L + + + +++Q
Sbjct: 331 ERPYGCRECGKAFSQQSQLVRHQRTHTGERPYPCKECGKAFSQSSTLAQHQRMHTGEKAQ 390
Query: 682 SVSRSTTPGSSNVTEESGVGGGLS--QTGSAQEDSPHPSSPSSSDIGEE------AGRSA 733
+ S +P V + G A S GE+ ++
Sbjct: 391 ILKASDSPSLVAHQRIHAVEKPFKCDECGKAFRWISRLSQHQLIHTGEKPYKCNKCTKAF 450
Query: 734 GVQQPALLRDRS-LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSA 792
G + R+ G C CGK F HL H RIHTGEKPY C C A +QS+
Sbjct: 451 GCSSRLIRHQRTHTGEKPFKCDECGKGFVQGSHLIQHQRIHTGEKPYVCNDCGKAFSQSS 510
Query: 793 SLKYHLERHHRER 805
SL YH H E+
Sbjct: 511 SLIYHQRIHKGEK 523
Score = 63.9 bits (154), Expect = 9e-10
Identities = 42/140 (30%), Positives = 61/140 (43%), Gaps = 19/140 (13%)
Query: 274 FRCTFCKGKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELISHVEKAHITAESAQG 331
F+CT C F+ +L +H RI KPY+C C A Q LI H ++ H G
Sbjct: 278 FKCTECGKAFRLSSKLIQHQRIHTGEKPYRCEECGKAFGQSSSLIHH-QRIHT------G 330
Query: 332 QGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNH 391
+ P G C CG+ FSQ L H R H + C+ CG+ F + L H
Sbjct: 331 ERPYG----------CRECGKAFSQQSQLVRHQRTHTGERPYPCKECGKAFSQSSTLAQH 380
Query: 392 MKVHLNKLSVKNKSPSDPEV 411
++H + + K+ P +
Sbjct: 381 QRMHTGEKAQILKASDSPSL 400
Score = 61.2 bits (147), Expect = 6e-09
Identities = 30/56 (53%), Positives = 33/56 (58%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQNG 808
C CGK FR S L H RIHTGEKPY+C C A QS+SL +H H ER G
Sbjct: 280 CTECGKAFRLSSKLIQHQRIHTGEKPYRCEECGKAFGQSSSLIHHQRIHTGERPYG 335
Score = 59.7 bits (143), Expect = 2e-08
Identities = 38/124 (30%), Positives = 56/124 (45%), Gaps = 19/124 (15%)
Query: 274 FRCTFCKGKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELISHVEKAHITAESAQG 331
+ C C F+ +L++H RI KP+KCT C A +LI H ++ H G
Sbjct: 250 YECAECGKVFRLCSQLNQHQRIHTGEKPFKCTECGKAFRLSSKLIQH-QRIHT------G 302
Query: 332 QGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNH 391
+ P +RCE CG+ F Q+ L H R H + C+ CG+ F + L H
Sbjct: 303 EKP----------YRCEECGKAFGQSSSLIHHQRIHTGERPYGCRECGKAFSQQSQLVRH 352
Query: 392 MKVH 395
+ H
Sbjct: 353 QRTH 356
Score = 54.3 bits (129), Expect = 7e-07
Identities = 26/59 (44%), Positives = 30/59 (50%)
Query: 747 GSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
G +C CGK FR L H RIHTGEKP+KC C A S+ L H H E+
Sbjct: 246 GEKPYECAECGKVFRLCSQLNQHQRIHTGEKPFKCTECGKAFRLSSKLIQHQRIHTGEK 304
Score = 52.8 bits (125), Expect = 2e-06
Identities = 46/180 (25%), Positives = 68/180 (37%), Gaps = 40/180 (22%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP +C +CG+ FR ++ H +H ++ +
Sbjct: 410 EKPFKCDECGKAFRWISRLSQHQLIHTGEKPYK--------------------------- 442
Query: 688 TPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSLG 747
+ T+ G L + + + P D E G+ VQ L++ + +
Sbjct: 443 ---CNKCTKAFGCSSRLIR----HQRTHTGEKPFKCD---ECGKGF-VQGSHLIQHQRIH 491
Query: 748 SAMKD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
+ K C CGK F S L H RIH GEKPY+C C A + S L H H ER
Sbjct: 492 TGEKPYVCNDCGKAFSQSSSLIYHQRIHKGEKPYECLQCGKAFSMSTQLTIHQRVHTGER 551
Score = 49.3 bits (116), Expect = 2e-05
Identities = 43/178 (24%), Positives = 65/178 (36%), Gaps = 12/178 (6%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP +C C + F +++ H R H ++ + D G G Q S +
Sbjct: 438 EKPYKCNKCTKAFGCSSRLIRHQRTHTGEKPFKCDEC--------GKGFVQGSHLIQHQR 489
Query: 688 TPGSSNVTEESGVGGGLSQTGSA-QEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDR-S 745
+ G SQ+ S H + + G++ + + R
Sbjct: 490 IHTGEKPYVCNDCGKAFSQSSSLIYHQRIHKGEKPYECL--QCGKAFSMSTQLTIHQRVH 547
Query: 746 LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHR 803
G C CGK F + L H IH G KPY+C C A ++S+ L H H R
Sbjct: 548 TGERPYKCNECGKAFSQNSTLFQHQIIHAGVKPYECSECGKAFSRSSYLIEHQRIHTR 605
Score = 32.7 bits (73), Expect = 2.3
Identities = 25/105 (23%), Positives = 35/105 (33%), Gaps = 26/105 (24%)
Query: 727 EEAGRSAGVQQPALLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHT------------ 774
+E G S QP + S + C CGK R + + +H I+T
Sbjct: 172 KELGSSGLDCQPLESQGESAEGMSQRCEECGKGIRATSDIALHWEINTQKISRCQECQKK 231
Query: 775 --------------GEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
GEKPY+C C + L H H E+
Sbjct: 232 LSDCLQGKHTNNCHGEKPYECAECGKVFRLCSQLNQHQRIHTGEK 276
>gi|40807465 zinc finger protein 341 [Homo sapiens]
Length = 847
Score = 89.7 bits (221), Expect = 2e-17
Identities = 76/282 (26%), Positives = 112/282 (39%), Gaps = 53/282 (18%)
Query: 126 KNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNL 185
K +K C C K F N L H+R+HTGEKPF+C C AQK N+K H++THK+
Sbjct: 311 KAQKLKCSYCDKSFTKNFDLQQHIRSHTGEKPFQCIACGRAFAQKSNVKKHMQTHKVWPP 370
Query: 186 GKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTLALQAN 245
G G V + + + ++ + L QP P P P A
Sbjct: 371 GHSGGTVSRNSVTVQVMALNPSRQEDEESTGLGQPLPG-APQPQAL-------------- 415
Query: 246 HSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRILHK---PYKC 302
A KP S Q V + + C FC KF +L H+ HK YKC
Sbjct: 416 ----STAGEEEGDKPESKQ--VVLIDSSYLCQFCPSKFSTYFQLKSHM-TQHKNEQVYKC 468
Query: 303 TL--CDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFL 360
+ C + + + H+ K+H Q +RC +CG+ F + L
Sbjct: 469 VVKSCAQTFPKLDTFLEHI-KSH----------------QEELSYRCHLCGKDFPSLYDL 511
Query: 361 KGHMRKH---------KDSFEHCCQICGRRFKEPWFLKNHMK 393
H H KD+ + C C ++ P L++H++
Sbjct: 512 GVHQYSHSLLPQHSPKKDNAVYKCVKCVNKYSTPEALEHHLQ 553
Score = 64.3 bits (155), Expect = 7e-10
Identities = 34/93 (36%), Positives = 51/93 (54%), Gaps = 9/93 (9%)
Query: 715 PHPSSPSSSDIGEEAGRSAGVQQPALLRDRSLGSAMKD------CPYCGKTFRTSHHLKV 768
P+P++P +S G G A PA L+ R +A K C YC K+F + L+
Sbjct: 276 PNPAAPMTSATG---GTVATFDSPATLKTRRAKAAGKPKAQKLKCSYCDKSFTKNFDLQQ 332
Query: 769 HLRIHTGEKPYKCPHCDYAGTQSASLKYHLERH 801
H+R HTGEKP++C C A Q +++K H++ H
Sbjct: 333 HIRSHTGEKPFQCIACGRAFAQKSNVKKHMQTH 365
Score = 58.2 bits (139), Expect = 5e-08
Identities = 57/270 (21%), Positives = 95/270 (35%), Gaps = 78/270 (28%)
Query: 125 RKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGN 184
+ N Y C C ++ L H++T T F CP+C + L+ HL TH G+
Sbjct: 528 KDNAVYKCVKCVNKYSTPEALEHHLQTATHN--FPCPHCQKVFPCERYLRRHLPTH--GS 583
Query: 185 LGKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTLALQA 244
G+ + +V C +
Sbjct: 584 GGRFKCQV---------------------------------------------CKKFFRR 598
Query: 245 NHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRILHKP---YK 301
H + AH KP ++C+ C+ F ++++L RH+ ++H+P YK
Sbjct: 599 EHYLKLHAHIHSGEKP-------------YKCSVCESAFNRKDKLKRHM-LIHEPFKKYK 644
Query: 302 CTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLK 361
C +E KAHI + S +C +C + FS+ L
Sbjct: 645 CPFSTHTGCSKEFNRPDKLKAHILSHSGM------------KLHKCALCSKSFSRRAHLA 692
Query: 362 GHMRKHKDSFEHCCQICGRRFKEPWFLKNH 391
H R H +++ C C + F +LK+H
Sbjct: 693 EHQRAHTGNYKFRCAGCAKGFSRHKYLKDH 722
Score = 56.6 bits (135), Expect = 2e-07
Identities = 24/49 (48%), Positives = 30/49 (61%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERH 801
C C K FR H+LK+H IH+GEKPYKC C+ A + LK H+ H
Sbjct: 589 CQVCKKFFRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIH 637
Score = 55.5 bits (132), Expect = 3e-07
Identities = 68/300 (22%), Positives = 100/300 (33%), Gaps = 73/300 (24%)
Query: 130 YPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPY--CDHRAAQKGNLKIHLRTHKLGNLGK 187
Y C C +F L HM H E+ +KC C + H+++H+
Sbjct: 438 YLCQFCPSKFSTYFQLKSHMTQHKNEQVYKCVVKSCAQTFPKLDTFLEHIKSHQ------ 491
Query: 188 GRGRVREENRLLHELEERAILRDK-----------QLKGSLLQPRPDLKPPPHAQQAPLA 236
EL R L K Q SLL P P
Sbjct: 492 ------------EELSYRCHLCGKDFPSLYDLGVHQYSHSLL---PQHSPKKDNAVYKCV 536
Query: 237 ACTLALQA----NHSVPDVAHPVPSPK-----PASVQEDAVAPAAG----FRCTFCKGKF 283
C H + H P P P P G F+C CK KF
Sbjct: 537 KCVNKYSTPEALEHHLQTATHNFPCPHCQKVFPCERYLRRHLPTHGSGGRFKCQVCK-KF 595
Query: 284 KKRE---ELDRHIRILHKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQ 340
+RE +L HI KPYKC++C+ A +++++L K H+ +
Sbjct: 596 FRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKL-----KRHMLIH------------E 638
Query: 341 SANEFRCEV-----CGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
+++C C + F++ LK H+ H H C +C + F L H + H
Sbjct: 639 PFKKYKCPFSTHTGCSKEFNRPDKLKAHILSHSGMKLHKCALCSKSFSRRAHLAEHQRAH 698
Score = 52.0 bits (123), Expect = 4e-06
Identities = 99/481 (20%), Positives = 155/481 (32%), Gaps = 87/481 (18%)
Query: 338 GEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLN 397
G+ A + +C C + F++ + L+ H+R H C CGR F + +K HM+ H
Sbjct: 308 GKPKAQKLKCSYCDKSFTKNFDLQQHIRSHTGEKPFQCIACGRAFAQKSNVKKHMQTH-- 365
Query: 398 KLSVKNKSPSDPEVPVPMGGMSQEAHANLYSRYLSCLQSGFMTPDKAGLSEPSQLYGKGE 457
K P V ++ + A SR +G P G +P L GE
Sbjct: 366 ----KVWPPGHSGGTVSRNSVTVQVMALNPSRQEDEESTGLGQP-LPGAPQPQALSTAGE 420
Query: 458 LPMKEKEALGKLLSPISSMAHGVPEGDKHSLLGCLNLVPPLKSSCIERLQAAAKAAEMDP 517
+ E+ +L S + P K S +L+ + M
Sbjct: 421 EEGDKPESKQVVLIDSSYLCQFCPS----------------KFSTYFQLK-----SHMTQ 459
Query: 518 VNSYQAWQLMARGMAMEHGFLSKEHPLQRNHEDTLANAGVLFDKEKREYVLVGA-DGSKQ 576
+ Q ++ + + A L ++H++ L+ L K+ +G S
Sbjct: 460 HKNEQVYKCVVKSCAQTFPKLDTFLEHIKSHQEELSYRCHLCGKDFPSLYDLGVHQYSHS 519
Query: 577 KMPADLVHSTKVGSQRDLPSKLDPLESSRDFLSHGLNQTLEYNLQGPGNMKEKPTE---- 632
+P HS K + K S+ + L H L QT +N P K P E
Sbjct: 520 LLPQ---HSPKKDNAVYKCVKCVNKYSTPEALEHHL-QTATHNFPCPHCQKVFPCERYLR 575
Query: 633 -------------CPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQE 679
C C + FR H + +H+ +H SG
Sbjct: 576 RHLPTHGSGGRFKCQVCKKFFRREHYLKLHAHIH--------------------SGEKPY 615
Query: 680 SQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPA 739
SV S + + P G S +P
Sbjct: 616 KCSVCESAFNRKDKLKRHMLI--------------HEPFKKYKCPFSTHTGCSKEFNRPD 661
Query: 740 LLRDRSL---GSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKY 796
L+ L G + C C K+F HL H R HTG ++C C ++ LK
Sbjct: 662 KLKAHILSHSGMKLHKCALCSKSFSRRAHLAEHQRAHTGNYKFRCAGCAKGFSRHKYLKD 721
Query: 797 H 797
H
Sbjct: 722 H 722
Score = 52.0 bits (123), Expect = 4e-06
Identities = 49/179 (27%), Positives = 68/179 (37%), Gaps = 27/179 (15%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP +C CGR F V H + HK G H G R S + Q +
Sbjct: 340 EKPFQCIACGRAFAQKSNVKKHMQTHKVWPPG-----HSGGTVSRNSVTVQVM-----AL 389
Query: 688 TPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSLG 747
P E +G+G L +P P + S++ GEE G +Q L+ L
Sbjct: 390 NPSRQEDEESTGLGQPLP-------GAPQPQALSTA--GEEEGDKPESKQVVLIDSSYL- 439
Query: 748 SAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKC--PHCDYAGTQSASLKYHLERHHRE 804
C +C F T LK H+ H E+ YKC C + + H++ H E
Sbjct: 440 -----CQFCPSKFSTYFQLKSHMTQHKNEQVYKCVVKSCAQTFPKLDTFLEHIKSHQEE 493
Score = 37.0 bits (84), Expect = 0.12
Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 9/56 (16%)
Query: 753 CPY-----CGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHR 803
CP+ C K F LK H+ H+G K +KC C ++S S + HL H R
Sbjct: 645 CPFSTHTGCSKEFNRPDKLKAHILSHSGMKLHKCALC----SKSFSRRAHLAEHQR 696
>gi|61676193 zinc finger protein 260 [Homo sapiens]
Length = 412
Score = 89.4 bits (220), Expect = 2e-17
Identities = 77/286 (26%), Positives = 116/286 (40%), Gaps = 55/286 (19%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH------K 181
+ Y C CGK F + L+ H + HTGEKPF+C C +QK L H H K
Sbjct: 134 KPYACKECGKAFNGKAYLTEHEKIHTGEKPFECNQCGRAFSQKQYLIKHQNIHTGKKPFK 193
Query: 182 LGNLGKGRGRVREENRLLHE--------LEERAILRDKQLKGSLLQPRPDLKPPPHAQQA 233
GK + +EN ++H+ E + + K SL++ + H +
Sbjct: 194 CSECGKAFSQ--KENLIIHQRIHTGEKPYECKGCGKAFIQKSSLIRHQRS-----HTGEK 246
Query: 234 PLAA--CTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDR 291
P C A ++ + KP ++C C F++++ L +
Sbjct: 247 PYTCKECGKAFSGKSNLTEHEKIHIGEKP-------------YKCNECGTIFRQKQYLIK 293
Query: 292 H--IRILHKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEV 349
H I KPY+C C A S+ LI HV + H G P + C+V
Sbjct: 294 HHNIHTGEKPYECNKCGKAFSRITSLIVHV-RIHT------GDKP----------YECKV 336
Query: 350 CGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
CG+ F Q+ L HMR H + C CG+ F + L HM++H
Sbjct: 337 CGKAFCQSSSLTVHMRSHTGEKPYGCNECGKAFSQFSTLALHMRIH 382
Score = 89.0 bits (219), Expect = 3e-17
Identities = 75/283 (26%), Positives = 110/283 (38%), Gaps = 38/283 (13%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGK 187
+ Y C C K F L H + HTGEK +C C ++ +L +HLR+H K
Sbjct: 25 KPYECNECRKTFSLKQNLVEHKKMHTGEKSHECTECGKVCSRVSSLTLHLRSHTGKKAYK 84
Query: 188 ----GRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAA--CTLA 241
G+ ++EN L H+ + K S+ P H P A C A
Sbjct: 85 CNKCGKAFSQKENFLSHQKHHTGEKPYECEKVSIQMPTIIRHQKNHTGTKPYACKECGKA 144
Query: 242 LQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRH--IRILHKP 299
+ + KP F C C F +++ L +H I KP
Sbjct: 145 FNGKAYLTEHEKIHTGEKP-------------FECNQCGRAFSQKQYLIKHQNIHTGKKP 191
Query: 300 YKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWF 359
+KC+ C A SQ+E LI H ++ H G+ P + C+ CG+ F Q
Sbjct: 192 FKCSECGKAFSQKENLIIH-QRIH------TGEKP----------YECKGCGKAFIQKSS 234
Query: 360 LKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVK 402
L H R H + C+ CG+ F L H K+H+ + K
Sbjct: 235 LIRHQRSHTGEKPYTCKECGKAFSGKSNLTEHEKIHIGEKPYK 277
Score = 76.6 bits (187), Expect = 1e-13
Identities = 51/191 (26%), Positives = 84/191 (43%), Gaps = 28/191 (14%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
+KP +C +CG+ F +++H R+H ++ E G ++ Q S + +
Sbjct: 189 KKPFKCSECGKAFSQKENLIIHQRIHTGEKPYECKGCGKAFIQKSSLIRHQRSHTGEKPY 248
Query: 688 T--------PGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPA 739
T G SN+TE + G + P+ + + Q+
Sbjct: 249 TCKECGKAFSGKSNLTEHEKIHIG---------EKPYKCNECGTIFR---------QKQY 290
Query: 740 LLRDRSLGSAMK--DCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYH 797
L++ ++ + K +C CGK F L VH+RIHTG+KPY+C C A QS+SL H
Sbjct: 291 LIKHHNIHTGEKPYECNKCGKAFSRITSLIVHVRIHTGDKPYECKVCGKAFCQSSSLTVH 350
Query: 798 LERHHRERQNG 808
+ H E+ G
Sbjct: 351 MRSHTGEKPYG 361
Score = 59.3 bits (142), Expect = 2e-08
Identities = 48/206 (23%), Positives = 74/206 (35%), Gaps = 26/206 (12%)
Query: 598 LDPLESSRDFLSHGLNQTLEYNLQGPGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDR 657
L+ L+ D L H T EKP EC +C + F +V H ++H ++
Sbjct: 5 LESLQHESDLLQHDQIHT-----------GEKPYECNECRKTFSLKQNLVEHKKMHTGEK 53
Query: 658 KGEEDGLHVGLDERRGSGSDQESQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHP 717
E G + S + + + G SQ + H
Sbjct: 54 SHE--------CTECGKVCSRVSSLTLHLRSHTGKKAYKCNKCGKAFSQKENFLSHQKHH 105
Query: 718 SSPSSSDIGEEAGRSAGVQQPALLRDRSLGSAMKD--CPYCGKTFRTSHHLKVHLRIHTG 775
+ + +Q P ++R + + K C CGK F +L H +IHTG
Sbjct: 106 TGEKPYEC-----EKVSIQMPTIIRHQKNHTGTKPYACKECGKAFNGKAYLTEHEKIHTG 160
Query: 776 EKPYKCPHCDYAGTQSASLKYHLERH 801
EKP++C C A +Q L H H
Sbjct: 161 EKPFECNQCGRAFSQKQYLIKHQNIH 186
Score = 58.5 bits (140), Expect = 4e-08
Identities = 24/54 (44%), Positives = 35/54 (64%)
Query: 127 NRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
++ Y C +CGK F +S L++HMR+HTGEKP+ C C +Q L +H+R H
Sbjct: 329 DKPYECKVCGKAFCQSSSLTVHMRSHTGEKPYGCNECGKAFSQFSTLALHMRIH 382
Score = 53.9 bits (128), Expect = 1e-06
Identities = 25/53 (47%), Positives = 31/53 (58%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
+ Y C CGK F S L+LHMR HTGEKP++C C +QK + H R H
Sbjct: 358 KPYGCNECGKAFSQFSTLALHMRIHTGEKPYQCSECGKAFSQKSHHIRHQRIH 410
Score = 52.0 bits (123), Expect = 4e-06
Identities = 39/178 (21%), Positives = 72/178 (40%), Gaps = 11/178 (6%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EK EC +CG+V + +H R H + + + ++ S Q+ + +
Sbjct: 52 EKSHECTECGKVCSRVSSLTLHLRSHTGKKAYKCNKCGKAFSQKENFLSHQKHHTGEKPY 111
Query: 688 TPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSLG 747
++ + + + TG+ P+ + + G+ A + + + G
Sbjct: 112 ECEKVSIQMPTIIRHQKNHTGT----KPY----ACKECGKAFNGKAYLTEHEKIHT---G 160
Query: 748 SAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
+C CG+ F +L H IHTG+KP+KC C A +Q +L H H E+
Sbjct: 161 EKPFECNQCGRAFSQKQYLIKHQNIHTGKKPFKCSECGKAFSQKENLIIHQRIHTGEK 218
Score = 48.5 bits (114), Expect = 4e-05
Identities = 25/71 (35%), Positives = 33/71 (46%)
Query: 747 GSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQ 806
G +C CGK L +HLR HTG+K YKC C A +Q + H + H E+
Sbjct: 51 GEKSHECTECGKVCSRVSSLTLHLRSHTGKKAYKCNKCGKAFSQKENFLSHQKHHTGEKP 110
Query: 807 NGAGPLSGQPP 817
+S Q P
Sbjct: 111 YECEKVSIQMP 121
Score = 35.0 bits (79), Expect = 0.47
Identities = 15/39 (38%), Positives = 22/39 (56%)
Query: 769 HLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQN 807
H +IHTGEKPY+C C + +L H + H E+ +
Sbjct: 17 HDQIHTGEKPYECNECRKTFSLKQNLVEHKKMHTGEKSH 55
>gi|134142822 zinc finger protein 133 [Homo sapiens]
Length = 653
Score = 88.2 bits (217), Expect = 5e-17
Identities = 83/311 (26%), Positives = 117/311 (37%), Gaps = 47/311 (15%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHK------ 181
+ Y C CG+ FR + L H RTH+ EKP+ C C H +Q L H RTH
Sbjct: 379 KPYACKECGRCFRQRTTLVNHQRTHSKEKPYVCGVCGHSFSQNSTLISHRRTHTGEKPYV 438
Query: 182 LGNLGKGRGRVREENR--LLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACT 239
G G+G NR +H E+ + +D +G Q H+ + P+
Sbjct: 439 CGVCGRGFSLKSHLNRHQNIHSGEKPIVCKDCG-RGFSQQSNLIRHQRTHSGEKPMVCGE 497
Query: 240 LALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIR--ILH 297
+ VAH + + + C C F + L RH R
Sbjct: 498 CGRGFSQKSNLVAH-----------QRTHSGERPYVCRECGRGFSHQAGLIRHKRKHSRE 546
Query: 298 KPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQA 357
KPY C C + LI+H ++AH + C CGQ F Q
Sbjct: 547 KPYMCRQCGLGFGNKSALITH-KRAHSEEKPCV----------------CRECGQGFLQK 589
Query: 358 WFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKNKSPSDPEVPVPMGG 417
L H H + C+ CGR F LK+H+ H SV ++ P P+ P P G
Sbjct: 590 SHLTLHQMTHTGEKPYVCKTCGRGFS----LKSHLSRHRKTTSVHHRLPVQPD-PEPCAG 644
Query: 418 MSQEAHANLYS 428
+ +LYS
Sbjct: 645 QPSD---SLYS 652
Score = 82.8 bits (203), Expect = 2e-15
Identities = 73/268 (27%), Positives = 103/268 (38%), Gaps = 55/268 (20%)
Query: 132 CPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGKGRGR 191
C CG+ F S L +H RTH+GEKP+ C C +QK NL IH RTH G+
Sbjct: 271 CRECGRGFNRKSTLIIHERTHSGEKPYMCSECGRGFSQKSNLIIHQRTHS----GEKPYV 326
Query: 192 VREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAA--CTLALQANHSVP 249
RE + ++ A++R ++ H ++ + C L ++
Sbjct: 327 CRECGKGFS--QKSAVVRHQR---------------THLEEKTIVCSDCGLGFSDRSNLI 369
Query: 250 DVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRI--LHKPYKCTLCDF 307
KP + C C F++R L H R KPY C +C
Sbjct: 370 SHQRTHSGEKP-------------YACKECGRCFRQRTTLVNHQRTHSKEKPYVCGVCGH 416
Query: 308 AASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKH 367
+ SQ LISH + H G+ P + C VCG+ FS L H H
Sbjct: 417 SFSQNSTLISH-RRTH------TGEKP----------YVCGVCGRGFSLKSHLNRHQNIH 459
Query: 368 KDSFEHCCQICGRRFKEPWFLKNHMKVH 395
C+ CGR F + L H + H
Sbjct: 460 SGEKPIVCKDCGRGFSQQSNLIRHQRTH 487
Score = 75.9 bits (185), Expect = 2e-13
Identities = 76/282 (26%), Positives = 105/282 (37%), Gaps = 47/282 (16%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH----KLG 183
+ Y C CG+ F S L +H RTH+GEKP+ C C +QK + H RTH +
Sbjct: 295 KPYMCSECGRGFSQKSNLIIHQRTHSGEKPYVCRECGKGFSQKSAVVRHQRTHLEEKTIV 354
Query: 184 NLGKGRGRVREENRLLHELEERAILRDKQLK----GSLLQPRPDL--KPPPHAQQAP--L 235
G G N + H +R +K G + R L H+++ P
Sbjct: 355 CSDCGLGFSDRSNLISH---QRTHSGEKPYACKECGRCFRQRTTLVNHQRTHSKEKPYVC 411
Query: 236 AACTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRH--I 293
C + N ++ KP + C C F + L+RH I
Sbjct: 412 GVCGHSFSQNSTLISHRRTHTGEKP-------------YVCGVCGRGFSLKSHLNRHQNI 458
Query: 294 RILHKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQV 353
KP C C SQ+ LI H ++ H G+ P GE CG+
Sbjct: 459 HSGEKPIVCKDCGRGFSQQSNLIRH-QRTH------SGEKPMVCGE----------CGRG 501
Query: 354 FSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
FSQ L H R H + C+ CGR F L H + H
Sbjct: 502 FSQKSNLVAHQRTHSGERPYVCRECGRGFSHQAGLIRHKRKH 543
Score = 67.8 bits (164), Expect = 7e-11
Identities = 61/203 (30%), Positives = 78/203 (38%), Gaps = 32/203 (15%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRK---GEEDGLHVGLDERRGSGSDQESQSVS 684
EKP C DCGR F ++ H R H ++ GE G G Q+S V+
Sbjct: 462 EKPIVCKDCGRGFSQQSNLIRHQRTHSGEKPMVCGE-----------CGRGFSQKSNLVA 510
Query: 685 RSTTPGSSNVTEESGVGGGLS-QTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRD 743
T G G S Q G + H S + + G G + AL+
Sbjct: 511 HQRTHSGERPYVCRECGRGFSHQAGLIRHKRKH--SREKPYMCRQCGLGFG-NKSALITH 567
Query: 744 RSLGSAMKDCPY--CGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERH 801
+ S K C CG+ F HL +H HTGEKPY C C + SLK HL RH
Sbjct: 568 KRAHSEEKPCVCRECGQGFLQKSHLTLHQMTHTGEKPYVCKTCG----RGFSLKSHLSRH 623
Query: 802 HRER--------QNGAGPLSGQP 816
+ Q P +GQP
Sbjct: 624 RKTTSVHHRLPVQPDPEPCAGQP 646
Score = 65.1 bits (157), Expect = 4e-10
Identities = 53/182 (29%), Positives = 76/182 (41%), Gaps = 16/182 (8%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVS--R 685
EKP C +CGR FR +V H R H +++ G+ G Q S +S R
Sbjct: 378 EKPYACKECGRCFRQRTTLVNHQRTHSKEKP-----YVCGVC---GHSFSQNSTLISHRR 429
Query: 686 STTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRS 745
+ T V G G L + ++ P + ++ GR QQ L+R +
Sbjct: 430 THTGEKPYVCGVCGRGFSLKSHLNRHQNIHSGEKPI---VCKDCGRGFS-QQSNLIRHQR 485
Query: 746 LGSAMKD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHR 803
S K C CG+ F +L H R H+GE+PY C C + A L H +H R
Sbjct: 486 THSGEKPMVCGECGRGFSQKSNLVAHQRTHSGERPYVCRECGRGFSHQAGLIRHKRKHSR 545
Query: 804 ER 805
E+
Sbjct: 546 EK 547
Score = 58.5 bits (140), Expect = 4e-08
Identities = 45/179 (25%), Positives = 69/179 (38%), Gaps = 10/179 (5%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP C +CGR F +++H R H ++ + G G Q+S +
Sbjct: 266 EKPIVCRECGRGFNRKSTLIIHERTHSGEKP--------YMCSECGRGFSQKSNLIIHQR 317
Query: 688 TPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRS-L 746
T G G SQ SA + + + G + + R+
Sbjct: 318 THSGEKPYVCRECGKGFSQK-SAVVRHQRTHLEEKTIVCSDCGLGFSDRSNLISHQRTHS 376
Query: 747 GSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
G C CG+ FR L H R H+ EKPY C C ++ +Q+++L H H E+
Sbjct: 377 GEKPYACKECGRCFRQRTTLVNHQRTHSKEKPYVCGVCGHSFSQNSTLISHRRTHTGEK 435
Score = 52.8 bits (125), Expect = 2e-06
Identities = 40/140 (28%), Positives = 59/140 (42%), Gaps = 15/140 (10%)
Query: 276 CTFCKGKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELISHVEKAHITAESAQ--- 330
C C F K L H RI KPY C +C+ S ++ L H +KAH +
Sbjct: 215 CGECGLSFSKMTNLLSHQRIHSGEKPYVCGVCEKGFSLKKSLARH-QKAHSGEKPIVCRE 273
Query: 331 -GQGPNGGGEQSANE--------FRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRR 381
G+G N +E + C CG+ FSQ L H R H + C+ CG+
Sbjct: 274 CGRGFNRKSTLIIHERTHSGEKPYMCSECGRGFSQKSNLIIHQRTHSGEKPYVCRECGKG 333
Query: 382 FKEPWFLKNHMKVHLNKLSV 401
F + + H + HL + ++
Sbjct: 334 FSQKSAVVRHQRTHLEEKTI 353
Score = 52.4 bits (124), Expect = 3e-06
Identities = 26/73 (35%), Positives = 36/73 (49%)
Query: 108 GQNLGIMSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRA 167
G+ + S ++ ++ + C CG+ F S L H RTH+GEKP C C
Sbjct: 443 GRGFSLKSHLNRHQNIHSGEKPIVCKDCGRGFSQQSNLIRHQRTHSGEKPMVCGECGRGF 502
Query: 168 AQKGNLKIHLRTH 180
+QK NL H RTH
Sbjct: 503 SQKSNLVAHQRTH 515
Score = 47.8 bits (112), Expect = 7e-05
Identities = 25/66 (37%), Positives = 33/66 (50%)
Query: 740 LLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLE 799
L R LG +C CG +F +L H RIH+GEKPY C C+ + SL H +
Sbjct: 202 LKRIEVLGFGTVNCGECGLSFSKMTNLLSHQRIHSGEKPYVCGVCEKGFSLKKSLARHQK 261
Query: 800 RHHRER 805
H E+
Sbjct: 262 AHSGEK 267
Score = 44.3 bits (103), Expect = 8e-04
Identities = 21/55 (38%), Positives = 26/55 (47%)
Query: 126 KNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
+ + Y C CG F S L H R H+ EKP C C QK +L +H TH
Sbjct: 545 REKPYMCRQCGLGFGNKSALITHKRAHSEEKPCVCRECGQGFLQKSHLTLHQMTH 599
>gi|27545332 zinc finger protein 133 [Homo sapiens]
Length = 653
Score = 88.2 bits (217), Expect = 5e-17
Identities = 83/311 (26%), Positives = 117/311 (37%), Gaps = 47/311 (15%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHK------ 181
+ Y C CG+ FR + L H RTH+ EKP+ C C H +Q L H RTH
Sbjct: 379 KPYACKECGRCFRQRTTLVNHQRTHSKEKPYVCGVCGHSFSQNSTLISHRRTHTGEKPYV 438
Query: 182 LGNLGKGRGRVREENR--LLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACT 239
G G+G NR +H E+ + +D +G Q H+ + P+
Sbjct: 439 CGVCGRGFSLKSHLNRHQNIHSGEKPIVCKDCG-RGFSQQSNLIRHQRTHSGEKPMVCGE 497
Query: 240 LALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIR--ILH 297
+ VAH + + + C C F + L RH R
Sbjct: 498 CGRGFSQKSNLVAH-----------QRTHSGERPYVCRECGRGFSHQAGLIRHKRKHSRE 546
Query: 298 KPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQA 357
KPY C C + LI+H ++AH + C CGQ F Q
Sbjct: 547 KPYMCRQCGLGFGNKSALITH-KRAHSEEKPCV----------------CRECGQGFLQK 589
Query: 358 WFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKNKSPSDPEVPVPMGG 417
L H H + C+ CGR F LK+H+ H SV ++ P P+ P P G
Sbjct: 590 SHLTLHQMTHTGEKPYVCKTCGRGFS----LKSHLSRHRKTTSVHHRLPVQPD-PEPCAG 644
Query: 418 MSQEAHANLYS 428
+ +LYS
Sbjct: 645 QPSD---SLYS 652
Score = 82.8 bits (203), Expect = 2e-15
Identities = 73/268 (27%), Positives = 103/268 (38%), Gaps = 55/268 (20%)
Query: 132 CPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGKGRGR 191
C CG+ F S L +H RTH+GEKP+ C C +QK NL IH RTH G+
Sbjct: 271 CRECGRGFNRKSTLIIHERTHSGEKPYMCSECGRGFSQKSNLIIHQRTHS----GEKPYV 326
Query: 192 VREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAA--CTLALQANHSVP 249
RE + ++ A++R ++ H ++ + C L ++
Sbjct: 327 CRECGKGFS--QKSAVVRHQR---------------THLEEKTIVCSDCGLGFSDRSNLI 369
Query: 250 DVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRI--LHKPYKCTLCDF 307
KP + C C F++R L H R KPY C +C
Sbjct: 370 SHQRTHSGEKP-------------YACKECGRCFRQRTTLVNHQRTHSKEKPYVCGVCGH 416
Query: 308 AASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKH 367
+ SQ LISH + H G+ P + C VCG+ FS L H H
Sbjct: 417 SFSQNSTLISH-RRTH------TGEKP----------YVCGVCGRGFSLKSHLNRHQNIH 459
Query: 368 KDSFEHCCQICGRRFKEPWFLKNHMKVH 395
C+ CGR F + L H + H
Sbjct: 460 SGEKPIVCKDCGRGFSQQSNLIRHQRTH 487
Score = 75.9 bits (185), Expect = 2e-13
Identities = 76/282 (26%), Positives = 105/282 (37%), Gaps = 47/282 (16%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH----KLG 183
+ Y C CG+ F S L +H RTH+GEKP+ C C +QK + H RTH +
Sbjct: 295 KPYMCSECGRGFSQKSNLIIHQRTHSGEKPYVCRECGKGFSQKSAVVRHQRTHLEEKTIV 354
Query: 184 NLGKGRGRVREENRLLHELEERAILRDKQLK----GSLLQPRPDL--KPPPHAQQAP--L 235
G G N + H +R +K G + R L H+++ P
Sbjct: 355 CSDCGLGFSDRSNLISH---QRTHSGEKPYACKECGRCFRQRTTLVNHQRTHSKEKPYVC 411
Query: 236 AACTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRH--I 293
C + N ++ KP + C C F + L+RH I
Sbjct: 412 GVCGHSFSQNSTLISHRRTHTGEKP-------------YVCGVCGRGFSLKSHLNRHQNI 458
Query: 294 RILHKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQV 353
KP C C SQ+ LI H ++ H G+ P GE CG+
Sbjct: 459 HSGEKPIVCKDCGRGFSQQSNLIRH-QRTH------SGEKPMVCGE----------CGRG 501
Query: 354 FSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
FSQ L H R H + C+ CGR F L H + H
Sbjct: 502 FSQKSNLVAHQRTHSGERPYVCRECGRGFSHQAGLIRHKRKH 543
Score = 67.8 bits (164), Expect = 7e-11
Identities = 61/203 (30%), Positives = 78/203 (38%), Gaps = 32/203 (15%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRK---GEEDGLHVGLDERRGSGSDQESQSVS 684
EKP C DCGR F ++ H R H ++ GE G G Q+S V+
Sbjct: 462 EKPIVCKDCGRGFSQQSNLIRHQRTHSGEKPMVCGE-----------CGRGFSQKSNLVA 510
Query: 685 RSTTPGSSNVTEESGVGGGLS-QTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRD 743
T G G S Q G + H S + + G G + AL+
Sbjct: 511 HQRTHSGERPYVCRECGRGFSHQAGLIRHKRKH--SREKPYMCRQCGLGFG-NKSALITH 567
Query: 744 RSLGSAMKDCPY--CGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERH 801
+ S K C CG+ F HL +H HTGEKPY C C + SLK HL RH
Sbjct: 568 KRAHSEEKPCVCRECGQGFLQKSHLTLHQMTHTGEKPYVCKTCG----RGFSLKSHLSRH 623
Query: 802 HRER--------QNGAGPLSGQP 816
+ Q P +GQP
Sbjct: 624 RKTTSVHHRLPVQPDPEPCAGQP 646
Score = 65.1 bits (157), Expect = 4e-10
Identities = 53/182 (29%), Positives = 76/182 (41%), Gaps = 16/182 (8%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVS--R 685
EKP C +CGR FR +V H R H +++ G+ G Q S +S R
Sbjct: 378 EKPYACKECGRCFRQRTTLVNHQRTHSKEKP-----YVCGVC---GHSFSQNSTLISHRR 429
Query: 686 STTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRS 745
+ T V G G L + ++ P + ++ GR QQ L+R +
Sbjct: 430 THTGEKPYVCGVCGRGFSLKSHLNRHQNIHSGEKPI---VCKDCGRGFS-QQSNLIRHQR 485
Query: 746 LGSAMKD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHR 803
S K C CG+ F +L H R H+GE+PY C C + A L H +H R
Sbjct: 486 THSGEKPMVCGECGRGFSQKSNLVAHQRTHSGERPYVCRECGRGFSHQAGLIRHKRKHSR 545
Query: 804 ER 805
E+
Sbjct: 546 EK 547
Score = 58.5 bits (140), Expect = 4e-08
Identities = 45/179 (25%), Positives = 69/179 (38%), Gaps = 10/179 (5%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP C +CGR F +++H R H ++ + G G Q+S +
Sbjct: 266 EKPIVCRECGRGFNRKSTLIIHERTHSGEKP--------YMCSECGRGFSQKSNLIIHQR 317
Query: 688 TPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRS-L 746
T G G SQ SA + + + G + + R+
Sbjct: 318 THSGEKPYVCRECGKGFSQK-SAVVRHQRTHLEEKTIVCSDCGLGFSDRSNLISHQRTHS 376
Query: 747 GSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
G C CG+ FR L H R H+ EKPY C C ++ +Q+++L H H E+
Sbjct: 377 GEKPYACKECGRCFRQRTTLVNHQRTHSKEKPYVCGVCGHSFSQNSTLISHRRTHTGEK 435
Score = 52.8 bits (125), Expect = 2e-06
Identities = 40/140 (28%), Positives = 59/140 (42%), Gaps = 15/140 (10%)
Query: 276 CTFCKGKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELISHVEKAHITAESAQ--- 330
C C F K L H RI KPY C +C+ S ++ L H +KAH +
Sbjct: 215 CGECGLSFSKMTNLLSHQRIHSGEKPYVCGVCEKGFSLKKSLARH-QKAHSGEKPIVCRE 273
Query: 331 -GQGPNGGGEQSANE--------FRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRR 381
G+G N +E + C CG+ FSQ L H R H + C+ CG+
Sbjct: 274 CGRGFNRKSTLIIHERTHSGEKPYMCSECGRGFSQKSNLIIHQRTHSGEKPYVCRECGKG 333
Query: 382 FKEPWFLKNHMKVHLNKLSV 401
F + + H + HL + ++
Sbjct: 334 FSQKSAVVRHQRTHLEEKTI 353
Score = 52.4 bits (124), Expect = 3e-06
Identities = 26/73 (35%), Positives = 36/73 (49%)
Query: 108 GQNLGIMSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRA 167
G+ + S ++ ++ + C CG+ F S L H RTH+GEKP C C
Sbjct: 443 GRGFSLKSHLNRHQNIHSGEKPIVCKDCGRGFSQQSNLIRHQRTHSGEKPMVCGECGRGF 502
Query: 168 AQKGNLKIHLRTH 180
+QK NL H RTH
Sbjct: 503 SQKSNLVAHQRTH 515
Score = 47.8 bits (112), Expect = 7e-05
Identities = 25/66 (37%), Positives = 33/66 (50%)
Query: 740 LLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLE 799
L R LG +C CG +F +L H RIH+GEKPY C C+ + SL H +
Sbjct: 202 LKRIEVLGFGTVNCGECGLSFSKMTNLLSHQRIHSGEKPYVCGVCEKGFSLKKSLARHQK 261
Query: 800 RHHRER 805
H E+
Sbjct: 262 AHSGEK 267
Score = 44.3 bits (103), Expect = 8e-04
Identities = 21/55 (38%), Positives = 26/55 (47%)
Query: 126 KNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
+ + Y C CG F S L H R H+ EKP C C QK +L +H TH
Sbjct: 545 REKPYMCRQCGLGFGNKSALITHKRAHSEEKPCVCRECGQGFLQKSHLTLHQMTH 599
>gi|170932473 zinc finger protein 786 [Homo sapiens]
Length = 782
Score = 88.2 bits (217), Expect = 5e-17
Identities = 81/291 (27%), Positives = 111/291 (38%), Gaps = 48/291 (16%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH------K 181
R + C CG+ F L H+R H+GE+PF+C CD R KG LK H TH
Sbjct: 507 RPFSCSECGRGFTHQCKLREHLRVHSGERPFQCLKCDKRFRLKGILKAHQHTHSKERPFS 566
Query: 182 LGNLGKGRGRVRE--ENRLLHELEE----RAILRDKQLKGSLLQPRPDLKPPPHAQQAPL 235
G GKG R + E+ +H E R +LKG LL L Q P
Sbjct: 567 CGECGKGFTRQSKLTEHLRVHSGERPFQCPECNRSFRLKGQLLS-HQRLHTGERPFQCPE 625
Query: 236 AACTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRI 295
++A+ + H P F C KG F K +L HIR
Sbjct: 626 CDKRYRVKADMKAHQLLHSGEMP---------------FSCECGKG-FVKHSKLIEHIRT 669
Query: 296 L--HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQV 353
KP++C CD + + +L+SH QG + G F C C +
Sbjct: 670 HTGEKPFQCPKCDKSFRLKAQLLSH-------------QGLHTG----ERPFHCPECDKN 712
Query: 354 FSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKNK 404
F + + H R H+ C CG+ F L H++VH N+
Sbjct: 713 FRERGHMLRHQRIHRPERPFACGDCGKGFIYKSKLAEHIRVHTKSCPAPNE 763
Score = 64.7 bits (156), Expect = 6e-10
Identities = 74/317 (23%), Positives = 106/317 (33%), Gaps = 66/317 (20%)
Query: 125 RKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFK-----------CPYCDHRAAQKGNL 173
R R + C +CGK FR L H+ HTG PF+ + HR Q+G
Sbjct: 235 RVQRHFRCGVCGKSFRRKLCLLRHLAAHTGRGPFRNADGEMCFRHELTHPSHRLPQQGEK 294
Query: 174 KIHLRTHKLGNLGKGRGRVREENRLLHELEERAILRDK----------QLKGSLL----- 218
+L + R R H E A R+ Q GS L
Sbjct: 295 PAQCTPCGKRSLPVDSTQAR---RCQHSREGPASWREGRGASSSVHSGQKPGSRLPQEGN 351
Query: 219 -QPRPDLKPPPHAQQAPLAACTLA----LQANHSVPDVAHPVPSP-------------KP 260
D + H + P + + A + P AH P +
Sbjct: 352 SHQEGDTEALQHGAEGPCSCSECGERSPMSARLASPCRAHTGEKPFQCAHCTKRFRLRRL 411
Query: 261 ASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELISH 318
V + A F C C F K+ +L HIR+ KP++C C Q +L+ H
Sbjct: 412 LQVHQHAHGGERPFSCRKCGKGFAKQCKLTEHIRVHSGEKPFRCAKCGRNFRQRGQLLRH 471
Query: 319 VEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQIC 378
++ H + F+C CG F L+ H +H C C
Sbjct: 472 -QRLHTDEKP----------------FQCPECGLSFRLESMLRAHRLRHGGERPFSCSEC 514
Query: 379 GRRFKEPWFLKNHMKVH 395
GR F L+ H++VH
Sbjct: 515 GRGFTHQCKLREHLRVH 531
Score = 60.5 bits (145), Expect = 1e-08
Identities = 55/193 (28%), Positives = 76/193 (39%), Gaps = 21/193 (10%)
Query: 628 EKPTECPDCGR----VFRTYHQVVVHSR---VHKRDRKGEEDGLHVGLDERRGSGSDQES 680
EKP +C CG+ V T + HSR R+ +G +H G ++ GS QE
Sbjct: 293 EKPAQCTPCGKRSLPVDSTQARRCQHSREGPASWREGRGASSSVHSG--QKPGSRLPQEG 350
Query: 681 QSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPAL 740
S T + E S+ G S +SP + GE+ + A +
Sbjct: 351 NSHQEGDTEALQHGAEGPC---SCSECGERSPMSARLASPCRAHTGEKPFQCAHCTKRFR 407
Query: 741 LRDRSL--------GSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSA 792
LR R L G C CGK F L H+R+H+GEKP++C C Q
Sbjct: 408 LR-RLLQVHQHAHGGERPFSCRKCGKGFAKQCKLTEHIRVHSGEKPFRCAKCGRNFRQRG 466
Query: 793 SLKYHLERHHRER 805
L H H E+
Sbjct: 467 QLLRHQRLHTDEK 479
Score = 60.5 bits (145), Expect = 1e-08
Identities = 56/201 (27%), Positives = 78/201 (38%), Gaps = 28/201 (13%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGE--EDGLHVGLDE-------RRGSGSDQ 678
EKP C CGR FR Q++ H R+H ++ + E GL L+ R G
Sbjct: 450 EKPFRCAKCGRNFRQRGQLLRHQRLHTDEKPFQCPECGLSFRLESMLRAHRLRHGGERPF 509
Query: 679 ESQSVSRSTTPGSSNVTEESGVGGG--------------LSQTGSAQEDSPHPSSP-SSS 723
R T + E V G L A + + P S
Sbjct: 510 SCSECGRGFTH-QCKLREHLRVHSGERPFQCLKCDKRFRLKGILKAHQHTHSKERPFSCG 568
Query: 724 DIGEEAGRSAGVQQPALLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPH 783
+ G+ R + + + LR S G CP C ++FR L H R+HTGE+P++CP
Sbjct: 569 ECGKGFTRQSKLTEH--LRVHS-GERPFQCPECNRSFRLKGQLLSHQRLHTGERPFQCPE 625
Query: 784 CDYAGTQSASLKYHLERHHRE 804
CD A +K H H E
Sbjct: 626 CDKRYRVKADMKAHQLLHSGE 646
Score = 59.7 bits (143), Expect = 2e-08
Identities = 57/248 (22%), Positives = 89/248 (35%), Gaps = 54/248 (21%)
Query: 126 KNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNL 185
K R + C CGK F S L+ H+R H+GE+PF+CP C+ KG L H R H
Sbjct: 561 KERPFSCGECGKGFTRQSKLTEHLRVHSGERPFQCPECNRSFRLKGQLLSHQRLH----- 615
Query: 186 GKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAA-CTLALQA 244
E E ++R ++ LL H+ + P + C
Sbjct: 616 ------TGERPFQCPECDKRYRVKADMKAHQLL----------HSGEMPFSCECGKGFVK 659
Query: 245 NHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRH--IRILHKPYKC 302
+ + + KP F+C C F+ + +L H + +P+ C
Sbjct: 660 HSKLIEHIRTHTGEKP-------------FQCPKCDKSFRLKAQLLSHQGLHTGERPFHC 706
Query: 303 TLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKG 362
CD + ++ H ++ H + F C CG+ F L
Sbjct: 707 PECDKNFRERGHMLRH-QRIH----------------RPERPFACGDCGKGFIYKSKLAE 749
Query: 363 HMRKHKDS 370
H+R H S
Sbjct: 750 HIRVHTKS 757
Score = 58.2 bits (139), Expect = 5e-08
Identities = 48/183 (26%), Positives = 69/183 (37%), Gaps = 37/183 (20%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
E+P +CP+C R FR Q++ H R+H GE D+R +D ++ + S
Sbjct: 590 ERPFQCPECNRSFRLKGQLLSHQRLHT----GERPFQCPECDKRYRVKADMKAHQLLHS- 644
Query: 688 TPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSLG 747
G + E G G S + E G ++P
Sbjct: 645 --GEMPFSCECGKG-----------------FVKHSKLIEHIRTHTG-EKPF-------- 676
Query: 748 SAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQN 807
CP C K+FR L H +HTGE+P+ CP CD + + H H ER
Sbjct: 677 ----QCPKCDKSFRLKAQLLSHQGLHTGERPFHCPECDKNFRERGHMLRHQRIHRPERPF 732
Query: 808 GAG 810
G
Sbjct: 733 ACG 735
Score = 53.5 bits (127), Expect = 1e-06
Identities = 45/186 (24%), Positives = 67/186 (36%), Gaps = 14/186 (7%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP +C C + FR + VH H +R + G G ++ +
Sbjct: 394 EKPFQCAHCTKRFRLRRLLQVHQHAHGGERPFS--------CRKCGKGFAKQCKLTEHIR 445
Query: 688 TPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSL- 746
+ G Q G + E G S ++ ++LR L
Sbjct: 446 VHSGEKPFRCAKCGRNFRQRGQLLRHQRLHTDEKPFQC-PECGLSFRLE--SMLRAHRLR 502
Query: 747 --GSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRE 804
G C CG+ F L+ HLR+H+GE+P++C CD LK H H +E
Sbjct: 503 HGGERPFSCSECGRGFTHQCKLREHLRVHSGERPFQCLKCDKRFRLKGILKAHQHTHSKE 562
Query: 805 RQNGAG 810
R G
Sbjct: 563 RPFSCG 568
Score = 48.5 bits (114), Expect = 4e-05
Identities = 47/180 (26%), Positives = 67/180 (37%), Gaps = 13/180 (7%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDER-RGSGSDQESQSVSRS 686
E+P C +CGR F ++ H RVH GE + D+R R G + Q
Sbjct: 506 ERPFSCSECGRGFTHQCKLREHLRVHS----GERPFQCLKCDKRFRLKGILKAHQHTHSK 561
Query: 687 TTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDR-S 745
P S G G ++ E S E RS ++ L R
Sbjct: 562 ERPFSCGEC-----GKGFTRQSKLTEHLRVHSGERPFQC-PECNRSFRLKGQLLSHQRLH 615
Query: 746 LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
G CP C K +R +K H +H+GE P+ C C + + L H+ H E+
Sbjct: 616 TGERPFQCPECDKRYRVKADMKAHQLLHSGEMPFSC-ECGKGFVKHSKLIEHIRTHTGEK 674
Score = 32.7 bits (73), Expect = 2.3
Identities = 33/138 (23%), Positives = 52/138 (37%), Gaps = 11/138 (7%)
Query: 647 VVHSRVHKRDRKGEEDGLHVGLDERRGSGS-------DQESQSVSRSTTPGSSNVTEESG 699
++ S V G E+ L G + SG D ESQ S + + G
Sbjct: 80 IICSSVDMHFDPGFEEQLFWGSQQAMNSGKTKSHFQLDPESQCSFGSFV----SFRPDQG 135
Query: 700 VGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSLGSAMKDCPYCGKT 759
+ G Q A+ P PS S + E + P L + S P CG++
Sbjct: 136 ITLGSPQRHDARAPPPLACGPSESTLKEGIPGPRNLDLPGLWDVPAWESTQHPWPVCGES 195
Query: 760 FRTSHHLKVHLRIHTGEK 777
++HL +H R H+ ++
Sbjct: 196 CWENNHLVMHQRGHSKDR 213
Score = 32.3 bits (72), Expect = 3.0
Identities = 40/132 (30%), Positives = 47/132 (35%), Gaps = 25/132 (18%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQNGAGPL 812
C CGK+FR L HL HTG P++ A + HR Q G P
Sbjct: 242 CGVCGKSFRRKLCLLRHLAAHTGRGPFR-----NADGEMCFRHELTHPSHRLPQQGEKPA 296
Query: 813 SGQPPNQDHKDEMSSKASLFIRPDILRGAFKGLPGIDFRGGPASQQWTSG-VLSSGDHSG 871
P K SL + R R GPAS W G SS HSG
Sbjct: 297 QCTP---------CGKRSLPVDSTQARRCQHS------REGPAS--WREGRGASSSVHSG 339
Query: 872 QATGMSSEVPSD 883
Q G S +P +
Sbjct: 340 QKPG--SRLPQE 349
Score = 31.2 bits (69), Expect = 6.8
Identities = 14/33 (42%), Positives = 18/33 (54%)
Query: 125 RKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKP 157
R R + C CGK F + S L+ H+R HT P
Sbjct: 727 RPERPFACGDCGKGFIYKSKLAEHIRVHTKSCP 759
>gi|34303941 zinc finger protein 567 [Homo sapiens]
Length = 616
Score = 88.2 bits (217), Expect = 5e-17
Identities = 76/283 (26%), Positives = 108/283 (38%), Gaps = 49/283 (17%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGK 187
+ Y C CGK FR + LSLH R HTGEKP+ C C QK NL +H RTH G+
Sbjct: 332 KPYECNDCGKSFRQKTTLSLHQRIHTGEKPYICKECGKSFHQKANLTVHQRTHT----GE 387
Query: 188 --------GRGRVREENRLLHEL---EERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLA 236
G+ ++ LHE EE+ + + K + H +
Sbjct: 388 KPYICNECGKSFSQKTTLALHEKTHNEEKPYICSECGKSFRQKTTLVAHQRTHTGEKSYE 447
Query: 237 A--CTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIR 294
C A + + D KP + C C F ++ L+ H R
Sbjct: 448 CPHCGKAFRMKSYLIDHHRTHTGEKP-------------YECNECGKSFSQKTNLNLHQR 494
Query: 295 IL--HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQ 352
I KPY C C + Q+ L H +K H +S + C CG+
Sbjct: 495 IHTGEKPYVCNECGKSFRQKATLTVH-QKIHTGQKS----------------YECPQCGK 537
Query: 353 VFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
FS+ +L H R H + C CG+ F++ L H + H
Sbjct: 538 AFSRKSYLIHHQRTHTGEKPYKCSECGKCFRQKTNLIVHQRTH 580
Score = 78.2 bits (191), Expect = 5e-14
Identities = 55/180 (30%), Positives = 81/180 (45%), Gaps = 12/180 (6%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EKP EC DCG+ FR + +H R+H GE+ + E S + + +V + T
Sbjct: 331 EKPYECNDCGKSFRQKTTLSLHQRIHT----GEKPYI---CKECGKSFHQKANLTVHQRT 383
Query: 688 TPGSSN-VTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRS- 745
G + E G T + E + + P I E G+S + + R+
Sbjct: 384 HTGEKPYICNECGKSFSQKTTLALHEKTHNEEKPY---ICSECGKSFRQKTTLVAHQRTH 440
Query: 746 LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
G +CP+CGK FR +L H R HTGEKPY+C C + +Q +L H H E+
Sbjct: 441 TGEKSYECPHCGKAFRMKSYLIDHHRTHTGEKPYECNECGKSFSQKTNLNLHQRIHTGEK 500
Score = 77.0 bits (188), Expect = 1e-13
Identities = 77/304 (25%), Positives = 113/304 (37%), Gaps = 49/304 (16%)
Query: 126 KNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH---KL 182
+ + Y C CG FR S L H RTHTGEKPF C C K L H RTH K
Sbjct: 246 EEKPYQCHQCGNAFRRKSYLIDHQRTHTGEKPFVCNECGKSFRLKTALTDHQRTHTGEKS 305
Query: 183 GNLGKGRGRVREENRLLHELEERAILRDKQL------KGSLLQPRPDLKPPPHAQQAPL- 235
+ R R ++ L+ +R +K K + L H + P
Sbjct: 306 YECLQCRNAFRLKSHLIR--HQRTHTGEKPYECNDCGKSFRQKTTLSLHQRIHTGEKPYI 363
Query: 236 ---AACTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRH 292
+ +AN +V H P + C C F ++ L H
Sbjct: 364 CKECGKSFHQKANLTVHQRTHTGEKP---------------YICNECGKSFSQKTTLALH 408
Query: 293 IRILH--KPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGG------------- 337
+ + KPY C+ C + Q+ L++H ++ H +S + P+ G
Sbjct: 409 EKTHNEEKPYICSECGKSFRQKTTLVAH-QRTHTGEKSY--ECPHCGKAFRMKSYLIDHH 465
Query: 338 -GEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHL 396
+ C CG+ FSQ L H R H + C CG+ F++ L H K+H
Sbjct: 466 RTHTGEKPYECNECGKSFSQKTNLNLHQRIHTGEKPYVCNECGKSFRQKATLTVHQKIHT 525
Query: 397 NKLS 400
+ S
Sbjct: 526 GQKS 529
Score = 74.3 bits (181), Expect = 7e-13
Identities = 69/275 (25%), Positives = 102/275 (37%), Gaps = 51/275 (18%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGK 187
+K+ C CGK F S+L LH H+ EKP++C C + +K L H RTH G
Sbjct: 220 KKHTCNECGKSFCRKSVLILHQGIHSEEKPYQCHQCGNAFRRKSYLIDHQRTHT-GEKPF 278
Query: 188 GRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTLALQANHS 247
+ RL L + + LQ R + H + Q H+
Sbjct: 279 VCNECGKSFRLKTALTDHQRTHTGEKSYECLQCRNAFRLKSHL---------IRHQRTHT 329
Query: 248 VPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRIL--HKPYKCTLC 305
KP + C C F+++ L H RI KPY C C
Sbjct: 330 ---------GEKP-------------YECNDCGKSFRQKTTLSLHQRIHTGEKPYICKEC 367
Query: 306 DFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMR 365
+ Q+ L H ++ H G+ P + C CG+ FSQ L H +
Sbjct: 368 GKSFHQKANLTVH-QRTHT------GEKP----------YICNECGKSFSQKTTLALHEK 410
Query: 366 KHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLS 400
H + + C CG+ F++ L H + H + S
Sbjct: 411 THNEEKPYICSECGKSFRQKTTLVAHQRTHTGEKS 445
Score = 67.0 bits (162), Expect = 1e-10
Identities = 52/181 (28%), Positives = 70/181 (38%), Gaps = 12/181 (6%)
Query: 627 KEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRS 686
+EKP C +CG+ FR +V H R H ++ E H G R +S +
Sbjct: 414 EEKPYICSECGKSFRQKTTLVAHQRTHTGEKSYECP--HCGKAFR------MKSYLIDHH 465
Query: 687 TTPGSSNVTEESGVGGGLSQ-TGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDR- 744
T E + G SQ T H + E G+S + + +
Sbjct: 466 RTHTGEKPYECNECGKSFSQKTNLNLHQRIHTGEKPY--VCNECGKSFRQKATLTVHQKI 523
Query: 745 SLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRE 804
G +CP CGK F +L H R HTGEKPYKC C Q +L H H E
Sbjct: 524 HTGQKSYECPQCGKAFSRKSYLIHHQRTHTGEKPYKCSECGKCFRQKTNLIVHQRTHTGE 583
Query: 805 R 805
+
Sbjct: 584 K 584
Score = 60.8 bits (146), Expect = 8e-09
Identities = 28/58 (48%), Positives = 35/58 (60%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNL 185
+ Y C CGK FR + L +H RTHTGEKP+ C C + K NL +H RTHK N+
Sbjct: 556 KPYKCSECGKCFRQKTNLIVHQRTHTGEKPYVCNECGKSFSYKRNLIVHQRTHKGENI 613
Score = 60.5 bits (145), Expect = 1e-08
Identities = 51/192 (26%), Positives = 80/192 (41%), Gaps = 16/192 (8%)
Query: 618 YNLQGPGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSD 677
YN + EK C +CG+ F +++H +H ++ + + G+
Sbjct: 209 YNKKRRATNIEKKHTCNECGKSFCRKSVLILHQGIHSEEKPYQ--------CHQCGNAFR 260
Query: 678 QESQSVS--RSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGV 735
++S + R+ T V E G L +T H S + R+A
Sbjct: 261 RKSYLIDHQRTHTGEKPFVCNECGKSFRL-KTALTDHQRTHTGEKSYECL---QCRNAFR 316
Query: 736 QQPALLRDRSLGSAMK--DCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSAS 793
+ L+R + + K +C CGK+FR L +H RIHTGEKPY C C + Q A+
Sbjct: 317 LKSHLIRHQRTHTGEKPYECNDCGKSFRQKTTLSLHQRIHTGEKPYICKECGKSFHQKAN 376
Query: 794 LKYHLERHHRER 805
L H H E+
Sbjct: 377 LTVHQRTHTGEK 388
Score = 60.5 bits (145), Expect = 1e-08
Identities = 65/250 (26%), Positives = 89/250 (35%), Gaps = 51/250 (20%)
Query: 121 EDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180
E + + Y C CGK FR + L H RTHTGEK ++CP+C K L H RTH
Sbjct: 409 EKTHNEEKPYICSECGKSFRQKTTLVAHQRTHTGEKSYECPHCGKAFRMKSYLIDHHRTH 468
Query: 181 KLGNLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAACTL 240
+ E N ++ L +L H + P +
Sbjct: 469 T-------GEKPYECNECGKSFSQKTNL--------------NLHQRIHTGEKPY----V 503
Query: 241 ALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRIL--HK 298
+ S A K + Q+ P G F ++ L H R K
Sbjct: 504 CNECGKSFRQKATLTVHQKIHTGQKSYECPQCG-------KAFSRKSYLIHHQRTHTGEK 556
Query: 299 PYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAW 358
PYKC+ C Q+ LI H ++ H G+ P + C CG+ FS
Sbjct: 557 PYKCSECGKCFRQKTNLIVH-QRTH------TGEKP----------YVCNECGKSFSYKR 599
Query: 359 FLKGHMRKHK 368
L H R HK
Sbjct: 600 NLIVHQRTHK 609
Score = 59.3 bits (142), Expect = 2e-08
Identities = 48/178 (26%), Positives = 68/178 (38%), Gaps = 10/178 (5%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687
EK ECP CG+ FR ++ H R H ++ E + ++ Q R
Sbjct: 443 EKSYECPHCGKAFRMKSYLIDHHRTHTGEKPYECNECGKSFSQKTNLNLHQ------RIH 496
Query: 688 TPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRS-L 746
T V E G T + + H S + G++ + + R+
Sbjct: 497 TGEKPYVCNECGKSFRQKATLTVHQKI-HTGQKSYEC--PQCGKAFSRKSYLIHHQRTHT 553
Query: 747 GSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRE 804
G C CGK FR +L VH R HTGEKPY C C + + +L H H E
Sbjct: 554 GEKPYKCSECGKCFRQKTNLIVHQRTHTGEKPYVCNECGKSFSYKRNLIVHQRTHKGE 611
Score = 55.1 bits (131), Expect = 4e-07
Identities = 38/131 (29%), Positives = 55/131 (41%), Gaps = 13/131 (9%)
Query: 50 LHPRPNPEEKPPASLEEKAHVPMSGQPMGSQMALLANQLGREVDTSLNGRVDLQQFLNGQ 109
LH + + EEKP E G+ + L+A+Q + G + G+
Sbjct: 407 LHEKTHNEEKPYICSE-------CGKSFRQKTTLVAHQ------RTHTGEKSYECPHCGK 453
Query: 110 NLGIMSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQ 169
+ S + D + Y C CGK F + L+LH R HTGEKP+ C C Q
Sbjct: 454 AFRMKSYLIDHHRTHTGEKPYECNECGKSFSQKTNLNLHQRIHTGEKPYVCNECGKSFRQ 513
Query: 170 KGNLKIHLRTH 180
K L +H + H
Sbjct: 514 KATLTVHQKIH 524
Score = 49.7 bits (117), Expect = 2e-05
Identities = 52/215 (24%), Positives = 81/215 (37%), Gaps = 31/215 (14%)
Query: 621 QGPGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQES 680
+ P N K P E GR+ + ++++ + R R E +G L + + E
Sbjct: 91 KNPVNSKNLPPEYDTHGRILKNVSELIISNLNPARKRLSEYNGYGKSLLSTKQETTHPEV 150
Query: 681 QSVSRST----------------TPGSS---NVTEESGVGGGLSQTGSAQEDSPHPS--- 718
+S ++S TP S N E+S + G T S +PS
Sbjct: 151 KSHNQSARAFSHNEVLMQYQKTETPAQSFGYNDCEKSFLQRGGLITHSRPYKGENPSVYN 210
Query: 719 ------SPSSSDIGEEAGRSAGVQQPALLRDRSLGSAMK--DCPYCGKTFRTSHHLKVHL 770
+ E G+S ++ L+ + + S K C CG FR +L H
Sbjct: 211 KKRRATNIEKKHTCNECGKSF-CRKSVLILHQGIHSEEKPYQCHQCGNAFRRKSYLIDHQ 269
Query: 771 RIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
R HTGEKP+ C C + +L H H E+
Sbjct: 270 RTHTGEKPFVCNECGKSFRLKTALTDHQRTHTGEK 304
Score = 44.3 bits (103), Expect = 8e-04
Identities = 33/137 (24%), Positives = 52/137 (37%), Gaps = 12/137 (8%)
Query: 270 PAAGFRCTFCKGKFKKREELDRHIRILHKPYKCTLCDFAASQEEELISHVEKAHITAESA 329
PA F C+ F +R L H R PYK + + ++ +++EK H E
Sbjct: 175 PAQSFGYNDCEKSFLQRGGLITHSR----PYKGE--NPSVYNKKRRATNIEKKHTCNECG 228
Query: 330 QGQGPNG------GGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFK 383
+ G ++C CG F + +L H R H C CG+ F+
Sbjct: 229 KSFCRKSVLILHQGIHSEEKPYQCHQCGNAFRRKSYLIDHQRTHTGEKPFVCNECGKSFR 288
Query: 384 EPWFLKNHMKVHLNKLS 400
L +H + H + S
Sbjct: 289 LKTALTDHQRTHTGEKS 305
Score = 36.2 bits (82), Expect = 0.21
Identities = 38/165 (23%), Positives = 59/165 (35%), Gaps = 38/165 (23%)
Query: 613 NQTLEYNLQGPGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERR 672
+Q NL + EKP C +CG+ FR + VH ++H + E +
Sbjct: 484 SQKTNLNLHQRIHTGEKPYVCNECGKSFRQKATLTVHQKIHTGQKSYE--------CPQC 535
Query: 673 GSGSDQESQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRS 732
G ++S + T TG + P+ S E G+
Sbjct: 536 GKAFSRKSYLIHHQRT-----------------HTG----EKPYKCS--------ECGKC 566
Query: 733 AGVQQPALLRDRS-LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGE 776
+ ++ R+ G C CGK+F +L VH R H GE
Sbjct: 567 FRQKTNLIVHQRTHTGEKPYVCNECGKSFSYKRNLIVHQRTHKGE 611
>gi|116256460 zinc finger protein 775 [Homo sapiens]
Length = 537
Score = 87.8 bits (216), Expect = 6e-17
Identities = 82/287 (28%), Positives = 112/287 (39%), Gaps = 60/287 (20%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHK------ 181
R++ C CGK F + S L++H R HTGE+P+ CP C R +QK NL HLR H
Sbjct: 279 RQFICNECGKSFTWWSSLNIHQRIHTGERPYACPECGRRFSQKPNLTRHLRNHTGERPHP 338
Query: 182 LGNLGKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAAC--- 238
+ G+G R++ LL L P AQ AP +C
Sbjct: 339 CPHCGRG---FRQKQHLLKHLRTHL---------------------PGAQAAPCPSCGKS 374
Query: 239 ---TLALQANHSVPDVAHP-VPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREEL-DRHI 293
AL+A+ VA P VP+ +P + P R + R+ L R
Sbjct: 375 CRSRAALRAHQRAHAVAEPAVPAGEPGDQPQAEAIPGLAARPRSSQRSPGARDTLWGRGQ 434
Query: 294 RILHKP-----YKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCE 348
L P + C C + S L H ++ H G+ P + C
Sbjct: 435 AGLAGPGEPRQFICNECGKSFSWWSALTIH-QRIHT------GERP----------YPCP 477
Query: 349 VCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
CG+ FSQ L H R H + C CGR F + L H +VH
Sbjct: 478 ECGRRFSQKPNLTRHRRNHTGERPYLCPACGRGFSQKQHLLKHQRVH 524
Score = 80.1 bits (196), Expect = 1e-14
Identities = 88/321 (27%), Positives = 119/321 (37%), Gaps = 69/321 (21%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHK------ 181
+ Y C CGK F L+ H R HTGE+PF CP C R +QK +L H +TH
Sbjct: 133 KPYLCGKCGKSFSQKPNLARHQRHHTGERPFCCPECARRFSQKQHLLKHQKTHSRPATHS 192
Query: 182 -------------LGNLGKGRGRVREENRL-LHELEERAILRDKQLKGSLLQPRPDLKPP 227
L + R R+ +R LHEL + A R + LQP P P
Sbjct: 193 CPECERCFRHQVGLRIHQRAHARDRQGSRAGLHELIQDAAAR----RACRLQPGP---PR 245
Query: 228 PHAQQAPLAACTLALQANHSVPDVAHPVPSPK-PASVQEDAVAPAAGFRCTFCKGKFKKR 286
+ A L C Q P V P+ P ++ F C C F
Sbjct: 246 GRPEWAWLGLC----QGWWGQPGARAAVSGPEGPGEPRQ--------FICNECGKSFTWW 293
Query: 287 EELDRHIRIL--HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANE 344
L+ H RI +PY C C SQ+ L H+ N GE+
Sbjct: 294 SSLNIHQRIHTGERPYACPECGRRFSQKPNLTRHLR--------------NHTGER---P 336
Query: 345 FRCEVCGQVFSQAWFLKGHMRKHKDSFEHC-CQICGRRFKEPWFLKNHMKVHLNKLSVKN 403
C CG+ F Q L H+R H + C CG+ + L+ H + H
Sbjct: 337 HPCPHCGRGFRQKQHLLKHLRTHLPGAQAAPCPSCGKSCRSRAALRAHQRAH-------- 388
Query: 404 KSPSDPEVPVPMGGMSQEAHA 424
+ ++P VP G +A A
Sbjct: 389 -AVAEPAVPAGEPGDQPQAEA 408
Score = 79.7 bits (195), Expect = 2e-14
Identities = 75/247 (30%), Positives = 94/247 (38%), Gaps = 34/247 (13%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGK 187
R Y CP CG+RF L+ H+R HTGE+P CP+C QK +L HLRTH G
Sbjct: 307 RPYACPECGRRFSQKPNLTRHLRNHTGERPHPCPHCGRGFRQKQHLLKHLRTHLPGAQAA 366
Query: 188 GRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPP---PHAQQAP-LAACTLALQ 243
+ R RA LR Q ++ +P P P A+ P LAA + Q
Sbjct: 367 PCPSCGKSCR------SRAALRAHQRAHAVAEPAVPAGEPGDQPQAEAIPGLAARPRSSQ 420
Query: 244 ANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRIL--HKPYK 301
+ D A E F C C F L H RI +PY
Sbjct: 421 RSPGARDTLWGRGQAGLAGPGEPRQ-----FICNECGKSFSWWSALTIHQRIHTGERPYP 475
Query: 302 CTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLK 361
C C SQ+ L H N GE+ + C CG+ FSQ L
Sbjct: 476 CPECGRRFSQKPNLTRHRR--------------NHTGERP---YLCPACGRGFSQKQHLL 518
Query: 362 GHMRKHK 368
H R H+
Sbjct: 519 KHQRVHR 525
Score = 77.8 bits (190), Expect = 6e-14
Identities = 70/252 (27%), Positives = 94/252 (37%), Gaps = 20/252 (7%)
Query: 633 CPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRSTTPGSS 692
CP+C R FR + +H R H RDR+G GLH + D ++ R
Sbjct: 193 CPECERCFRHQVGLRIHQRAHARDRQGSRAGLHELIQ-------DAAARRACRLQPGPPR 245
Query: 693 NVTEESGVG---GGLSQTGS-AQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDR-SLG 747
E + +G G Q G+ A P I E G+S + R G
Sbjct: 246 GRPEWAWLGLCQGWWGQPGARAAVSGPEGPGEPRQFICNECGKSFTWWSSLNIHQRIHTG 305
Query: 748 SAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQN 807
CP CG+ F +L HLR HTGE+P+ CPHC Q L HL H Q
Sbjct: 306 ERPYACPECGRRFSQKPNLTRHLRNHTGERPHPCPHCGRGFRQKQHLLKHLRTHLPGAQA 365
Query: 808 GAGPLSGQPPNQDHKDEMSSKASLFIRPDILRG------AFKGLPGIDFRGGPASQQWTS 861
P G+ +A P + G + +PG+ R P S Q +
Sbjct: 366 APCPSCGKSCRSRAALRAHQRAHAVAEPAVPAGEPGDQPQAEAIPGLAAR--PRSSQRSP 423
Query: 862 GVLSSGDHSGQA 873
G + GQA
Sbjct: 424 GARDTLWGRGQA 435
Score = 66.2 bits (160), Expect = 2e-10
Identities = 51/181 (28%), Positives = 73/181 (40%), Gaps = 17/181 (9%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEE-DGLHVGLDERRGSGSDQESQSVSRS 686
E+P CP CGR FR ++ H R H + R + Q + +V+
Sbjct: 334 ERPHPCPHCGRGFRQKQHLLKHLRTHLPGAQAAPCPSCGKSCRSRAALRAHQRAHAVAEP 393
Query: 687 TTPGSS--NVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDR 744
P + + + G ++ S+Q SP + D G+ AG+ P R
Sbjct: 394 AVPAGEPGDQPQAEAIPGLAARPRSSQR------SPGARDTLWGRGQ-AGLAGPGEPRQF 446
Query: 745 SLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRE 804
C CGK+F L +H RIHTGE+PY CP C +Q +L H H E
Sbjct: 447 I-------CNECGKSFSWWSALTIHQRIHTGERPYPCPECGRRFSQKPNLTRHRRNHTGE 499
Query: 805 R 805
R
Sbjct: 500 R 500
Score = 63.2 bits (152), Expect = 2e-09
Identities = 46/145 (31%), Positives = 69/145 (47%), Gaps = 9/145 (6%)
Query: 42 QLSHAFPE-LHPRPNPEEKPPASLEEKAHVPMSGQPMGSQMALLANQ-LGREVDTSLNGR 99
Q +HA E P P ++P A +A ++ +P SQ + A L L G
Sbjct: 385 QRAHAVAEPAVPAGEPGDQPQA----EAIPGLAARPRSSQRSPGARDTLWGRGQAGLAGP 440
Query: 100 VDLQQFLN---GQNLGIMSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEK 156
+ +QF+ G++ S ++ + R YPCP CG+RF L+ H R HTGE+
Sbjct: 441 GEPRQFICNECGKSFSWWSALTIHQRIHTGERPYPCPECGRRFSQKPNLTRHRRNHTGER 500
Query: 157 PFKCPYCDHRAAQKGNLKIHLRTHK 181
P+ CP C +QK +L H R H+
Sbjct: 501 PYLCPACGRGFSQKQHLLKHQRVHR 525
Score = 62.4 bits (150), Expect = 3e-09
Identities = 37/98 (37%), Positives = 45/98 (45%), Gaps = 1/98 (1%)
Query: 708 GSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSLGSAMKDCPYCGKTFRTSHHLK 767
G + SP + P+ D G AGR+ G L S G C CGK F LK
Sbjct: 65 GQEESGSPRWAPPTEQDAGL-AGRAPGSASGPLSPSLSSGEGHFVCLDCGKRFSWWSSLK 123
Query: 768 VHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
+H R HTGEKPY C C + +Q +L H H ER
Sbjct: 124 IHQRTHTGEKPYLCGKCGKSFSQKPNLARHQRHHTGER 161
Score = 52.0 bits (123), Expect = 4e-06
Identities = 38/140 (27%), Positives = 57/140 (40%), Gaps = 1/140 (0%)
Query: 665 HVGLDERRGSGSDQESQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSD 724
H GL R+ G + S +P + TE+ G + ++ SP SS
Sbjct: 48 HRGLPPRQTMGRPRALGGQEESGSPRWAPPTEQDAGLAGRAPGSASGPLSPSLSSGEGHF 107
Query: 725 IGEEAGRSAGVQQPALLRDRS-LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPH 783
+ + G+ + R+ G C CGK+F +L H R HTGE+P+ CP
Sbjct: 108 VCLDCGKRFSWWSSLKIHQRTHTGEKPYLCGKCGKSFSQKPNLARHQRHHTGERPFCCPE 167
Query: 784 CDYAGTQSASLKYHLERHHR 803
C +Q L H + H R
Sbjct: 168 CARRFSQKQHLLKHQKTHSR 187
Score = 45.1 bits (105), Expect = 5e-04
Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 2/79 (2%)
Query: 736 QQPALLRDRS--LGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSAS 793
Q+P L R + G CP C + F HL H + H+ + CP C+
Sbjct: 146 QKPNLARHQRHHTGERPFCCPECARRFSQKQHLLKHQKTHSRPATHSCPECERCFRHQVG 205
Query: 794 LKYHLERHHRERQNGAGPL 812
L+ H H R+RQ L
Sbjct: 206 LRIHQRAHARDRQGSRAGL 224
Score = 34.3 bits (77), Expect = 0.80
Identities = 18/51 (35%), Positives = 23/51 (45%)
Query: 345 FRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
F C CG+ FS LK H R H + C CG+ F + L H + H
Sbjct: 107 FVCLDCGKRFSWWSSLKIHQRTHTGEKPYLCGKCGKSFSQKPNLARHQRHH 157
Score = 31.2 bits (69), Expect = 6.8
Identities = 12/27 (44%), Positives = 16/27 (59%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHK 654
E+P CP CGR F ++ H RVH+
Sbjct: 499 ERPYLCPACGRGFSQKQHLLKHQRVHR 525
>gi|209862791 zinc finger protein 90 [Homo sapiens]
Length = 601
Score = 87.4 bits (215), Expect = 8e-17
Identities = 75/295 (25%), Positives = 113/295 (38%), Gaps = 55/295 (18%)
Query: 126 KNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNL 185
+ + Y C CGK F+ +SILS H R HTGEKP+KC C + + LRTHK +
Sbjct: 309 EEKPYKCEECGKAFKLSSILSTHKRIHTGEKPYKCEEC----GKAFRRSLVLRTHKRIHT 364
Query: 186 GKGRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAA--CTLALQ 243
G E+ DK K + H+++ P C A +
Sbjct: 365 G-----------------EKPYKCDKCGKAFISSSLLYKHKISHSEKKPYKCEECGKAFK 407
Query: 244 ANH--SVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRILH---K 298
+ ++ ++H P ++C C FK+ L H +I+H K
Sbjct: 408 RSSTLTIHKISHTEEKP---------------YKCQECDKVFKRSSALSTH-KIIHSGEK 451
Query: 299 PYKCTLCDFAASQEEEL----ISHVEKAHITAESAQGQGPNGGG-------EQSANEFRC 347
PYKC C A + L ISH E+ + N ++C
Sbjct: 452 PYKCEECGKAFKRSSNLTTHKISHTEEKLYKCQECDKAFKYSSALSTHKIIHSGENPYKC 511
Query: 348 EVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVK 402
E CG+ F ++ L H H + + C+ CG+ FK L +H H + K
Sbjct: 512 EECGKAFKRSSVLSKHKIIHTGAKPYKCEECGKAFKRSSQLTSHKISHTGEKPYK 566
Score = 75.9 bits (185), Expect = 2e-13
Identities = 72/295 (24%), Positives = 111/295 (37%), Gaps = 45/295 (15%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGK 187
++Y C CGK +++S L+ H R HTGEK +KC C L H R H K
Sbjct: 227 KRYKCEDCGKELKYSSTLTAHKRIHTGEKRYKCEDCGKELKYSSTLTAHKRIHTGEKPYK 286
Query: 188 ----GRGRVREENRLLHEL---EERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAA--C 238
GR + +H++ EE+ ++ K L H + P C
Sbjct: 287 CDKCGRAFISSSILYVHKISHTEEKPYKCEECGKAFKLSSILSTHKRIHTGEKPYKCEEC 346
Query: 239 ------TLALQANHSVPDVAHPVPSPKPASV---------QEDAVAPAAGFRCTFCKGKF 283
+L L+ + + P K + + + ++C C F
Sbjct: 347 GKAFRRSLVLRTHKRIHTGEKPYKCDKCGKAFISSSLLYKHKISHSEKKPYKCEECGKAF 406
Query: 284 KKREELDRHIRILH---KPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQ 340
K+ L H +I H KPYKC CD + L +H + H G+ P
Sbjct: 407 KRSSTLTIH-KISHTEEKPYKCQECDKVFKRSSALSTH-KIIH------SGEKP------ 452
Query: 341 SANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
++CE CG+ F ++ L H H + + CQ C + FK L H +H
Sbjct: 453 ----YKCEECGKAFKRSSNLTTHKISHTEEKLYKCQECDKAFKYSSALSTHKIIH 503
Score = 68.6 bits (166), Expect = 4e-11
Identities = 74/305 (24%), Positives = 112/305 (36%), Gaps = 55/305 (18%)
Query: 115 SQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLK 174
S I D +K + C CGK F +S L+ H + HTGE KC C + N
Sbjct: 160 SNRHKIRDTGKK--PFKCIECGKAFNQSSTLATHKKIHTGEITCKCEEC----GKAFNRS 213
Query: 175 IHLRTHKLGNLGKGRGRVRE------------ENRLLHELEERAILRD--KQLK-GSLLQ 219
HL +HK + G+ R + + ++ +H E+R D K+LK S L
Sbjct: 214 SHLTSHKRIHTGEKRYKCEDCGKELKYSSTLTAHKRIHTGEKRYKCEDCGKELKYSSTLT 273
Query: 220 PRPDLKPPPHAQQAPLAACTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFC 279
+ + + V ++H P ++C C
Sbjct: 274 AHKRIHTGEKPYKCDKCGRAFISSSILYVHKISHTEEKP---------------YKCEEC 318
Query: 280 KGKFKKREELDRHIRIL--HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGG 337
FK L H RI KPYKC C A + L +H ++ H G+ P
Sbjct: 319 GKAFKLSSILSTHKRIHTGEKPYKCEECGKAFRRSLVLRTH-KRIH------TGEKP--- 368
Query: 338 GEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLN 397
++C+ CG+ F + L H H + + C+ CG+ FK L H H
Sbjct: 369 -------YKCDKCGKAFISSSLLYKHKISHSEKKPYKCEECGKAFKRSSTLTIHKISHTE 421
Query: 398 KLSVK 402
+ K
Sbjct: 422 EKPYK 426
Score = 68.2 bits (165), Expect = 5e-11
Identities = 70/280 (25%), Positives = 99/280 (35%), Gaps = 51/280 (18%)
Query: 132 CPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH------KLGNL 185
C CGK F +S L+ H R HTGEK +KC C L H R H K +
Sbjct: 203 CEECGKAFNRSSHLTSHKRIHTGEKRYKCEDCGKELKYSSTLTAHKRIHTGEKRYKCEDC 262
Query: 186 GK--GRGRVREENRLLHELEERAILRDKQLKGSLLQPRPDLKPPPHAQQAPLAA--CTLA 241
GK ++ +H E+ DK + + + H ++ P C A
Sbjct: 263 GKELKYSSTLTAHKRIH-TGEKPYKCDKCGRAFISSSILYVHKISHTEEKPYKCEECGKA 321
Query: 242 LQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHIRIL--HKP 299
+ + + KP ++C C F++ L H RI KP
Sbjct: 322 FKLSSILSTHKRIHTGEKP-------------YKCEECGKAFRRSLVLRTHKRIHTGEKP 368
Query: 300 YKCTLCDFAASQEEEL----ISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFS 355
YKC C A L ISH EK ++CE CG+ F
Sbjct: 369 YKCDKCGKAFISSSLLYKHKISHSEK---------------------KPYKCEECGKAFK 407
Query: 356 QAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVH 395
++ L H H + + CQ C + FK L H +H
Sbjct: 408 RSSTLTIHKISHTEEKPYKCQECDKVFKRSSALSTHKIIH 447
Score = 62.0 bits (149), Expect = 4e-09
Identities = 49/183 (26%), Positives = 74/183 (40%), Gaps = 18/183 (9%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR--KGEEDGLHVGLDERRGSGSDQESQSVSR 685
EK +C DCG+ + + H R+H ++ K E+ G E + S + + +
Sbjct: 226 EKRYKCEDCGKELKYSSTLTAHKRIHTGEKRYKCEDCG-----KELKYSSTLTAHKRIHT 280
Query: 686 STTPGSSNVTEESGVGGGLSQTG--SAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRD 743
P + + + + S E+ P+ EE G++ +
Sbjct: 281 GEKPYKCDKCGRAFISSSILYVHKISHTEEKPYKC--------EECGKAFKLSSILSTHK 332
Query: 744 R-SLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHH 802
R G C CGK FR S L+ H RIHTGEKPYKC C A S+ L H H
Sbjct: 333 RIHTGEKPYKCEECGKAFRRSLVLRTHKRIHTGEKPYKCDKCGKAFISSSLLYKHKISHS 392
Query: 803 RER 805
++
Sbjct: 393 EKK 395
Score = 61.6 bits (148), Expect = 5e-09
Identities = 60/224 (26%), Positives = 89/224 (39%), Gaps = 35/224 (15%)
Query: 608 LSHGLNQTLEYNLQGPGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDR--KGEEDG-- 663
+SH + + + ++ G +KP +C +CG+ F + H ++H + K EE G
Sbjct: 153 VSHIFSNSNRHKIRDTG---KKPFKCIECGKAFNQSSTLATHKKIHTGEITCKCEECGKA 209
Query: 664 ------------LHVGLDERRGSGSDQESQSVSRSTTPGSSNV--------TEESGVGGG 703
+H G E+R D + ST + E+ G
Sbjct: 210 FNRSSHLTSHKRIHTG--EKRYKCEDCGKELKYSSTLTAHKRIHTGEKRYKCEDCGKELK 267
Query: 704 LSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSLGSAMKD--CPYCGKTFR 761
S T +A + P D + GR A + L + + K C CGK F+
Sbjct: 268 YSSTLTAHKRIHTGEKPYKCD---KCGR-AFISSSILYVHKISHTEEKPYKCEECGKAFK 323
Query: 762 TSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRER 805
S L H RIHTGEKPYKC C A +S L+ H H E+
Sbjct: 324 LSSILSTHKRIHTGEKPYKCEECGKAFRRSLVLRTHKRIHTGEK 367
Score = 58.2 bits (139), Expect = 5e-08
Identities = 69/291 (23%), Positives = 98/291 (33%), Gaps = 71/291 (24%)
Query: 124 ARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH--- 180
A +++ + C K S + H TG+KPFKC C Q L H + H
Sbjct: 139 ATQSKVFQCDTYVKVSHIFSNSNRHKIRDTGKKPFKCIECGKAFNQSSTLATHKKIHTGE 198
Query: 181 ---KLGNLGKGRGRVRE--ENRLLHELEERAILRD--KQLKGSLLQPRPDLKPPPHAQQA 233
K GK R ++ +H E+R D K+LK
Sbjct: 199 ITCKCEECGKAFNRSSHLTSHKRIHTGEKRYKCEDCGKELK------------------- 239
Query: 234 PLAACTLALQANHSVPDVAHPVPSPKPASVQEDAVAPAAGFRCTFCKGKFKKREELDRHI 293
+S AH K E ++C C + K L H
Sbjct: 240 ------------YSSTLTAH-----KRIHTGEKR------YKCEDCGKELKYSSTLTAHK 276
Query: 294 RIL--HKPYKCTLCDFAASQEEELISHVEKAHITAESAQGQGPNGGGEQSANEFRCEVCG 351
RI KPYKC C A I +V K T E ++CE CG
Sbjct: 277 RIHTGEKPYKCDKCGRAFISSS--ILYVHKISHTEE---------------KPYKCEECG 319
Query: 352 QVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVK 402
+ F + L H R H + C+ CG+ F+ L+ H ++H + K
Sbjct: 320 KAFKLSSILSTHKRIHTGEKPYKCEECGKAFRRSLVLRTHKRIHTGEKPYK 370
Score = 57.0 bits (136), Expect = 1e-07
Identities = 46/184 (25%), Positives = 75/184 (40%), Gaps = 18/184 (9%)
Query: 627 KEKPTECPDCGRVFRTYHQVVVHSRVHKRDR--KGEEDGLHVGLDERRGSGSDQESQSVS 684
+EKP +C +CG+ F+ + H R+H ++ K EE G R S + + +
Sbjct: 309 EEKPYKCEECGKAFKLSSILSTHKRIHTGEKPYKCEECGKAF-----RRSLVLRTHKRIH 363
Query: 685 RSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDR 744
P + ++ + L P EE G++ ++ + L
Sbjct: 364 TGEKPYKCDKCGKAFISSSLLYKHKISHSEKKPYKC------EECGKA--FKRSSTLTIH 415
Query: 745 SLGSAMKD---CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERH 801
+ + C C K F+ S L H IH+GEKPYKC C A +S++L H H
Sbjct: 416 KISHTEEKPYKCQECDKVFKRSSALSTHKIIHSGEKPYKCEECGKAFKRSSNLTTHKISH 475
Query: 802 HRER 805
E+
Sbjct: 476 TEEK 479
Score = 57.0 bits (136), Expect = 1e-07
Identities = 47/177 (26%), Positives = 70/177 (39%), Gaps = 12/177 (6%)
Query: 627 KEKPTECPDCGRVFRTYHQVVVHSRVHKRDR--KGEEDGLHVGLDERRGSGSDQESQSVS 684
+EKP +C +C +VF+ + H +H ++ K EE G +R S S +
Sbjct: 421 EEKPYKCQECDKVFKRSSALSTHKIIHSGEKPYKCEECGKAF----KRSSNLTTHKISHT 476
Query: 685 RSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDR 744
+ LS T +P + G+ RS+ + + ++
Sbjct: 477 EEKLYKCQECDKAFKYSSALS-THKIIHSGENPYK--CEECGKAFKRSSVLSKHKIIHT- 532
Query: 745 SLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERH 801
G+ C CGK F+ S L H HTGEKPYKC C A S+ L H H
Sbjct: 533 --GAKPYKCEECGKAFKRSSQLTSHKISHTGEKPYKCEECGKAFNLSSDLNTHKRIH 587
Score = 54.7 bits (130), Expect = 6e-07
Identities = 52/182 (28%), Positives = 70/182 (38%), Gaps = 16/182 (8%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR--KGEEDGLHVGLDERRGSGSDQESQSVSR 685
EKP +C CGR F + + VH H ++ K EE G L + R
Sbjct: 282 EKPYKCDKCGRAFISSSILYVHKISHTEEKPYKCEECGKAFKLSSILSTHK--------R 333
Query: 686 STTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRS 745
T EE G S + P D + G+ A + L + +
Sbjct: 334 IHTGEKPYKCEECGKAFRRSLVLRTHKRIHTGEKPYKCD---KCGK-AFISSSLLYKHKI 389
Query: 746 LGSAMKD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHR 803
S K C CGK F+ S L +H HT EKPYKC CD +S++L H H
Sbjct: 390 SHSEKKPYKCEECGKAFKRSSTLTIHKISHTEEKPYKCQECDKVFKRSSALSTHKIIHSG 449
Query: 804 ER 805
E+
Sbjct: 450 EK 451
Score = 53.5 bits (127), Expect = 1e-06
Identities = 47/187 (25%), Positives = 76/187 (40%), Gaps = 24/187 (12%)
Query: 627 KEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRS 686
++KP +C +CG+ F+ + +H H ++ + QE V +
Sbjct: 393 EKKPYKCEECGKAFKRSSTLTIHKISHTEEKPYK----------------CQECDKVFKR 436
Query: 687 TTPGSSNVTEESGVGG-GLSQTGSAQEDSPHPSSPSSSDIGEEAGR-----SAGVQQPAL 740
++ S++ SG + G A + S + ++ S E+ + A AL
Sbjct: 437 SSALSTHKIIHSGEKPYKCEECGKAFKRSSNLTTHKISHTEEKLYKCQECDKAFKYSSAL 496
Query: 741 LRDRSLGSAMKD--CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHL 798
+ + S C CGK F+ S L H IHTG KPYKC C A +S+ L H
Sbjct: 497 STHKIIHSGENPYKCEECGKAFKRSSVLSKHKIIHTGAKPYKCEECGKAFKRSSQLTSHK 556
Query: 799 ERHHRER 805
H E+
Sbjct: 557 ISHTGEK 563
Score = 52.8 bits (125), Expect = 2e-06
Identities = 25/54 (46%), Positives = 29/54 (53%)
Query: 753 CPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQ 806
C CGK F S HL H RIHTGEK YKC C S++L H H E++
Sbjct: 203 CEECGKAFNRSSHLTSHKRIHTGEKRYKCEDCGKELKYSSTLTAHKRIHTGEKR 256
Score = 50.8 bits (120), Expect = 8e-06
Identities = 25/60 (41%), Positives = 35/60 (58%), Gaps = 4/60 (6%)
Query: 128 RKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGK 187
+ Y C CGK F+ +S L+ H +HTGEKP+KC C + NL L THK ++G+
Sbjct: 535 KPYKCEECGKAFKRSSQLTSHKISHTGEKPYKCEEC----GKAFNLSSDLNTHKRIHIGQ 590
Score = 45.8 bits (107), Expect = 3e-04
Identities = 24/63 (38%), Positives = 29/63 (46%)
Query: 744 RSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHR 803
R G C CGK F S L H +IHTGE KC C A +S+ L H H
Sbjct: 166 RDTGKKPFKCIECGKAFNQSSTLATHKKIHTGEITCKCEECGKAFNRSSHLTSHKRIHTG 225
Query: 804 ERQ 806
E++
Sbjct: 226 EKR 228
Score = 38.9 bits (89), Expect = 0.032
Identities = 35/165 (21%), Positives = 57/165 (34%), Gaps = 34/165 (20%)
Query: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDR--------KGEEDGLHVGLDERRGSGS--- 676
EKP +C +CG+ F+ + H H ++ K + + + SG
Sbjct: 450 EKPYKCEECGKAFKRSSNLTTHKISHTEEKLYKCQECDKAFKYSSALSTHKIIHSGENPY 509
Query: 677 --DQESQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAG 734
++ ++ RS+ + + G A + S +S S GE+ +
Sbjct: 510 KCEECGKAFKRSSVLSKHKIIHTGAKPYKCEECGKAFKRSSQLTSHKISHTGEKPYK--- 566
Query: 735 VQQPALLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPY 779
C CGK F S L H RIH G+K Y
Sbjct: 567 ------------------CEECGKAFNLSSDLNTHKRIHIGQKAY 593
Score = 34.7 bits (78), Expect = 0.61
Identities = 15/44 (34%), Positives = 23/44 (52%)
Query: 115 SQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPF 158
SQ++ + + Y C CGK F +S L+ H R H G+K +
Sbjct: 550 SQLTSHKISHTGEKPYKCEECGKAFNLSSDLNTHKRIHIGQKAY 593
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,333,954
Number of Sequences: 37866
Number of extensions: 3071339
Number of successful extensions: 58361
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1065
Number of HSP's successfully gapped in prelim test: 144
Number of HSP's that attempted gapping in prelim test: 10046
Number of HSP's gapped (non-prelim): 31429
length of query: 1300
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1186
effective length of database: 13,930,794
effective search space: 16521921684
effective search space used: 16521921684
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.