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Search of human proteins with 7657437
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657437 sestrin 1 [Homo sapiens]
(551 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657437 sestrin 1 [Homo sapiens] 1133 0.0
gi|31377591 sestrin 3 [Homo sapiens] 613 e-175
gi|13899299 sestrin 2 [Homo sapiens] 528 e-150
gi|48762740 phosphodiesterase 9A isoform l [Homo sapiens] 40 0.004
gi|48762750 phosphodiesterase 9A isoform o [Homo sapiens] 39 0.012
gi|48762748 phosphodiesterase 9A isoform n [Homo sapiens] 39 0.012
gi|48762746 phosphodiesterase 9A isoform m [Homo sapiens] 39 0.012
gi|48762738 phosphodiesterase 9A isoform k [Homo sapiens] 39 0.012
gi|48762734 phosphodiesterase 9A isoform i [Homo sapiens] 39 0.012
gi|48762732 phosphodiesterase 9A isoform h [Homo sapiens] 39 0.012
gi|48762726 phosphodiesterase 9A isoform f [Homo sapiens] 39 0.012
gi|48762724 phosphodiesterase 9A isoform e [Homo sapiens] 39 0.012
gi|48762722 phosphodiesterase 9A isoform d [Homo sapiens] 39 0.012
gi|48762720 phosphodiesterase 9A isoform c [Homo sapiens] 39 0.012
gi|48762718 phosphodiesterase 9A isoform b [Homo sapiens] 39 0.012
gi|4505675 phosphodiesterase 9A isoform a [Homo sapiens] 39 0.012
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 32 1.2
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 32 1.2
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 32 2.0
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 32 2.0
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 32 2.0
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 32 2.0
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 31 2.6
gi|215422388 death-domain associated protein isoform a [Homo sap... 31 2.6
gi|215422366 death-domain associated protein isoform b [Homo sap... 31 2.6
gi|50428935 BPY2 interacting protein 1 [Homo sapiens] 31 2.6
gi|82830424 gon-4-like isoform a [Homo sapiens] 31 2.6
gi|24308265 methyltransferase like 14 [Homo sapiens] 30 4.4
gi|55749531 splicing factor 3B subunit 2 [Homo sapiens] 30 4.4
gi|4759140 sodium/hydrogen exchanger regulatory factor 1 [Homo s... 30 5.7
>gi|7657437 sestrin 1 [Homo sapiens]
Length = 551
Score = 1133 bits (2930), Expect = 0.0
Identities = 551/551 (100%), Positives = 551/551 (100%)
Query: 1 MAEGENEVRWDGLCSRDSTTRETALENIRQTILRKTEYLRSVKETPHRPSDGLSNTESSD 60
MAEGENEVRWDGLCSRDSTTRETALENIRQTILRKTEYLRSVKETPHRPSDGLSNTESSD
Sbjct: 1 MAEGENEVRWDGLCSRDSTTRETALENIRQTILRKTEYLRSVKETPHRPSDGLSNTESSD 60
Query: 61 GLNKLLAHLLMLSKRCPFKDVREKSEFILKSIQELGIRIPRPLGQGPSRFIPEKEILQVG 120
GLNKLLAHLLMLSKRCPFKDVREKSEFILKSIQELGIRIPRPLGQGPSRFIPEKEILQVG
Sbjct: 61 GLNKLLAHLLMLSKRCPFKDVREKSEFILKSIQELGIRIPRPLGQGPSRFIPEKEILQVG 120
Query: 121 SEDAQMHALFADSFAALGRLDNITLVMVFHPQYLESFLKTQHYLLQMDGPLPLHYRHYIG 180
SEDAQMHALFADSFAALGRLDNITLVMVFHPQYLESFLKTQHYLLQMDGPLPLHYRHYIG
Sbjct: 121 SEDAQMHALFADSFAALGRLDNITLVMVFHPQYLESFLKTQHYLLQMDGPLPLHYRHYIG 180
Query: 181 IMAAARHQCSYLVNLHVNDFLHVGGDPKWLNGLENAPQKLQNLGELNKVLAHRPWLITKE 240
IMAAARHQCSYLVNLHVNDFLHVGGDPKWLNGLENAPQKLQNLGELNKVLAHRPWLITKE
Sbjct: 181 IMAAARHQCSYLVNLHVNDFLHVGGDPKWLNGLENAPQKLQNLGELNKVLAHRPWLITKE 240
Query: 241 HIEGLLKAEEHSWSLAELVHAVVLLTHYHSLASFTFGCGISPEIHCDGGHTFRPPSVSNY 300
HIEGLLKAEEHSWSLAELVHAVVLLTHYHSLASFTFGCGISPEIHCDGGHTFRPPSVSNY
Sbjct: 241 HIEGLLKAEEHSWSLAELVHAVVLLTHYHSLASFTFGCGISPEIHCDGGHTFRPPSVSNY 300
Query: 301 CICDITNGNHSVDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQEEMASRF 360
CICDITNGNHSVDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQEEMASRF
Sbjct: 301 CICDITNGNHSVDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQEEMASRF 360
Query: 361 EIEKRESMFVFSSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQDYCWEDHGY 420
EIEKRESMFVFSSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQDYCWEDHGY
Sbjct: 361 EIEKRESMFVFSSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQDYCWEDHGY 420
Query: 421 SLVNRLYPDVGQLIDEKFHIAYNLTYNTMAMHKDVDTSMLRRAIWNYIHCMFGIRYDDYD 480
SLVNRLYPDVGQLIDEKFHIAYNLTYNTMAMHKDVDTSMLRRAIWNYIHCMFGIRYDDYD
Sbjct: 421 SLVNRLYPDVGQLIDEKFHIAYNLTYNTMAMHKDVDTSMLRRAIWNYIHCMFGIRYDDYD 480
Query: 481 YGEINQLLDRSFKVYIKTVVCTPEKVTKRMYDSFWRQFKHSEKVHVNLLLIEARMQAELL 540
YGEINQLLDRSFKVYIKTVVCTPEKVTKRMYDSFWRQFKHSEKVHVNLLLIEARMQAELL
Sbjct: 481 YGEINQLLDRSFKVYIKTVVCTPEKVTKRMYDSFWRQFKHSEKVHVNLLLIEARMQAELL 540
Query: 541 YALRAITRYMT 551
YALRAITRYMT
Sbjct: 541 YALRAITRYMT 551
>gi|31377591 sestrin 3 [Homo sapiens]
Length = 492
Score = 613 bits (1580), Expect = e-175
Identities = 297/466 (63%), Positives = 371/466 (79%), Gaps = 14/466 (3%)
Query: 97 IRIPRPLGQGPSRFIPEKEILQVGSEDAQMHALFADSFAALGRLDNITLVMVFHPQYLES 156
IR+ +PL +GPS FIPEKE++Q + D + + L + ++ GRLDNIT VM H QYLES
Sbjct: 30 IRVSQPLTRGPSAFIPEKEVVQANTVDERTNFL-VEEYSTSGRLDNITQVMSLHTQYLES 88
Query: 157 FLKTQHYLLQMDGPLPLHYRHYIGIMAAARHQCSYLVNLHVNDFLHVGGDPKWLNGLENA 216
FL++Q Y+L+MDGPLPL YRHYI IMAAARHQCSYL+N+HV++FL GG +WLNGLE
Sbjct: 89 FLRSQFYMLRMDGPLPLPYRHYIAIMAAARHQCSYLINMHVDEFLKTGGIAEWLNGLEYV 148
Query: 217 PQKLQNLGELNKVLAHRPWLITKEHIEGLLKAEEHSWSLAELVHAVVLLTHYHSLASFTF 276
PQ+L+NL E+NK+LAHRPWLITKEHI+ L+K E++WSL ELVHAVVLL HYH+LASF F
Sbjct: 149 PQRLKNLNEINKLLAHRPWLITKEHIQKLVKTGENNWSLPELVHAVVLLAHYHALASFVF 208
Query: 277 GCGISPEIHCDGGHTFRPPSVSNYCICDITNGNHSVDEMPVNSAENVSVSDSFFEVEALM 336
G GI+PE + + FR SV+N+C+CD+ N N+ E S N + DS E+EALM
Sbjct: 209 GSGINPERDPEISNGFRLISVNNFCVCDLANDNNI--ENASLSGSNFGIVDSLSELEALM 266
Query: 337 EKMRQLQECRDEEEASQEEMASRFEIEKRESMFVFSSD----------DEEVTPARAVSR 386
E+M++LQE R++EEASQEEM++RFE EK+ES+FV S D ++++ VSR
Sbjct: 267 ERMKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSDFEDDMIITSDVSR 326
Query: 387 HFEDTSYGYKDFSRHGM-HVPTFRVQDYCWEDHGYSLVNRLYPDVGQLIDEKFHIAYNLT 445
+ ED +GY+DF+R G H+PTFR QDY WE+HG+SLVNRLY D+G L+DEKF + YNLT
Sbjct: 327 YIEDPGFGYEDFARRGEEHLPTFRAQDYTWENHGFSLVNRLYSDIGHLLDEKFRMVYNLT 386
Query: 446 YNTMAMHKDVDTSMLRRAIWNYIHCMFGIRYDDYDYGEINQLLDRSFKVYIKTVVCTPEK 505
YNTMA H+DVDT+MLRRA++NY+HCMFGIRYDDYDYGE+NQLL+RS KVYIKTV C PE+
Sbjct: 387 YNTMATHEDVDTTMLRRALFNYVHCMFGIRYDDYDYGEVNQLLERSLKVYIKTVTCYPER 446
Query: 506 VTKRMYDSFWRQFKHSEKVHVNLLLIEARMQAELLYALRAITRYMT 551
TKRMYDS+WRQFKHSEKVHVNLLL+EARMQAELLYALRAITR++T
Sbjct: 447 TTKRMYDSYWRQFKHSEKVHVNLLLMEARMQAELLYALRAITRHLT 492
>gi|13899299 sestrin 2 [Homo sapiens]
Length = 480
Score = 528 bits (1361), Expect = e-150
Identities = 268/450 (59%), Positives = 330/450 (73%), Gaps = 14/450 (3%)
Query: 105 QGPSRFIPEKEILQVGSEDAQMHALFADSFAALGRLDNITLVMVFHPQYLESFLKTQHYL 164
+GPS FIP +E+L+ G+E + H L ++ + GR+DN+ +VM HP Y SF + + L
Sbjct: 42 RGPSAFIPVEEVLREGAESLEQH-LGLEALMSSGRVDNLAVVMGLHPDYFTSFWRLHYLL 100
Query: 165 LQMDGPLPLHYRHYIGIMAAARHQCSYLVNLHVNDFLHVGGDPKWLNGLENAPQKLQNLG 224
L DGPL +RHYI IMAAARHQCSYLV H+ +FL GGDP+WL GL AP+KL+ L
Sbjct: 101 LHTDGPLASSWRHYIAIMAAARHQCSYLVGSHMAEFLQTGGDPEWLLGLHRAPEKLRKLS 160
Query: 225 ELNKVLAHRPWLITKEHIEGLLKAEEHSWSLAELVHAVVLLTHYHSLASFTFGCGISPEI 284
E+NK+LAHRPWLITKEHI+ LLK EH+WSLAEL+ A+VLLTH HSL+SF FGCGI PE
Sbjct: 161 EINKLLAHRPWLITKEHIQALLKTGEHTWSLAELIQALVLLTHCHSLSSFVFGCGILPEG 220
Query: 285 HCDGGHTFRPPSVSNYCICDITNGNHSVDEMPVNSAENVSVSDSFFEVEALMEKMRQLQE 344
DG + P+ + + P+N++ +S +VEALME+M+QLQE
Sbjct: 221 DADGSPAPQAPTPPS-------EQSSPPSRDPLNNSGGF---ESARDVEALMERMQQLQE 270
Query: 345 CRDEEEA-SQEEMASRFEIEKRESMFVF-SSDDEEVTPARAVSRHFEDTSYGYKDFSRHG 402
+E SQEEM SRFE+EK ES+ V S+D E +P + ED ++GY+DF+R G
Sbjct: 271 SLLRDEGTSQEEMESRFELEKSESLLVTPSADILEPSPHPDMLCFVEDPTFGYEDFTRRG 330
Query: 403 MHVP-TFRVQDYCWEDHGYSLVNRLYPDVGQLIDEKFHIAYNLTYNTMAMHKDVDTSMLR 461
P TFR QDY WEDHGYSL+ RLYP+ GQL+DEKF AY+LTYNT+AMH VDTS+LR
Sbjct: 331 AQAPPTFRAQDYTWEDHGYSLIQRLYPEGGQLLDEKFQAAYSLTYNTIAMHSGVDTSVLR 390
Query: 462 RAIWNYIHCMFGIRYDDYDYGEINQLLDRSFKVYIKTVVCTPEKVTKRMYDSFWRQFKHS 521
RAIWNYIHC+FGIRYDDYDYGE+NQLL+R+ KVYIKTV C PEK T+RMY+ FWR F+HS
Sbjct: 391 RAIWNYIHCVFGIRYDDYDYGEVNQLLERNLKVYIKTVACYPEKTTRRMYNLFWRHFRHS 450
Query: 522 EKVHVNLLLIEARMQAELLYALRAITRYMT 551
EKVHVNLLL+EARMQA LLYALRAITRYMT
Sbjct: 451 EKVHVNLLLLEARMQAALLYALRAITRYMT 480
>gi|48762740 phosphodiesterase 9A isoform l [Homo sapiens]
Length = 491
Score = 40.4 bits (93), Expect = 0.004
Identities = 36/146 (24%), Positives = 69/146 (47%), Gaps = 9/146 (6%)
Query: 292 FRPPSV-SNYCICDITNGNHSVDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEE 350
FR SV S C T ++E+ A +++V + E+E L K+ ++++C+ + +
Sbjct: 47 FRTHSVQSETCGHQATLRAFKINELKAEVANHLAVLEKRVELEGL--KVVEIEKCKSDIK 104
Query: 351 ASQEEMASRFEIEKRESMFVFSSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRV 410
+EE+A+R + F + +++TP R V + Y + + PTF V
Sbjct: 105 KMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTY---PKYLLSPETIEALRKPTFDV 161
Query: 411 QDYCWE-DHGYSLVNRLYPDVGQLID 435
+ WE + S + +Y D+G + D
Sbjct: 162 --WLWEPNEMLSCLEHMYHDLGLVRD 185
>gi|48762750 phosphodiesterase 9A isoform o [Homo sapiens]
Length = 567
Score = 38.9 bits (89), Expect = 0.012
Identities = 29/125 (23%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 312 VDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQEEMASRFEIEKRESMFVF 371
++E+ A +++V + E+E L K+ ++++C+ + + +EE+A+R + F
Sbjct: 144 INELKAEVANHLAVLEKRVELEGL--KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSF 201
Query: 372 SSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQDYCWE-DHGYSLVNRLYPDV 430
+ +++TP R V + Y + + PTF V + WE + S + +Y D+
Sbjct: 202 LDNHKKLTPRRDVPTY---PKYLLSPETIEALRKPTFDV--WLWEPNEMLSCLEHMYHDL 256
Query: 431 GQLID 435
G + D
Sbjct: 257 GLVRD 261
>gi|48762748 phosphodiesterase 9A isoform n [Homo sapiens]
Length = 552
Score = 38.9 bits (89), Expect = 0.012
Identities = 29/125 (23%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 312 VDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQEEMASRFEIEKRESMFVF 371
++E+ A +++V + E+E L K+ ++++C+ + + +EE+A+R + F
Sbjct: 129 INELKAEVANHLAVLEKRVELEGL--KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSF 186
Query: 372 SSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQDYCWE-DHGYSLVNRLYPDV 430
+ +++TP R V + Y + + PTF V + WE + S + +Y D+
Sbjct: 187 LDNHKKLTPRRDVPTY---PKYLLSPETIEALRKPTFDV--WLWEPNEMLSCLEHMYHDL 241
Query: 431 GQLID 435
G + D
Sbjct: 242 GLVRD 246
>gi|48762746 phosphodiesterase 9A isoform m [Homo sapiens]
Length = 526
Score = 38.9 bits (89), Expect = 0.012
Identities = 29/125 (23%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 312 VDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQEEMASRFEIEKRESMFVF 371
++E+ A +++V + E+E L K+ ++++C+ + + +EE+A+R + F
Sbjct: 103 INELKAEVANHLAVLEKRVELEGL--KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSF 160
Query: 372 SSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQDYCWE-DHGYSLVNRLYPDV 430
+ +++TP R V + Y + + PTF V + WE + S + +Y D+
Sbjct: 161 LDNHKKLTPRRDVPTY---PKYLLSPETIEALRKPTFDV--WLWEPNEMLSCLEHMYHDL 215
Query: 431 GQLID 435
G + D
Sbjct: 216 GLVRD 220
>gi|48762738 phosphodiesterase 9A isoform k [Homo sapiens]
Length = 459
Score = 38.9 bits (89), Expect = 0.012
Identities = 29/125 (23%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 312 VDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQEEMASRFEIEKRESMFVF 371
++E+ A +++V + E+E L K+ ++++C+ + + +EE+A+R + F
Sbjct: 36 INELKAEVANHLAVLEKRVELEGL--KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSF 93
Query: 372 SSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQDYCWE-DHGYSLVNRLYPDV 430
+ +++TP R V + Y + + PTF V + WE + S + +Y D+
Sbjct: 94 LDNHKKLTPRRDVPTY---PKYLLSPETIEALRKPTFDV--WLWEPNEMLSCLEHMYHDL 148
Query: 431 GQLID 435
G + D
Sbjct: 149 GLVRD 153
>gi|48762734 phosphodiesterase 9A isoform i [Homo sapiens]
Length = 433
Score = 38.9 bits (89), Expect = 0.012
Identities = 29/125 (23%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 312 VDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQEEMASRFEIEKRESMFVF 371
++E+ A +++V + E+E L K+ ++++C+ + + +EE+A+R + F
Sbjct: 10 INELKAEVANHLAVLEKRVELEGL--KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSF 67
Query: 372 SSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQDYCWE-DHGYSLVNRLYPDV 430
+ +++TP R V + Y + + PTF V + WE + S + +Y D+
Sbjct: 68 LDNHKKLTPRRDVPTY---PKYLLSPETIEALRKPTFDV--WLWEPNEMLSCLEHMYHDL 122
Query: 431 GQLID 435
G + D
Sbjct: 123 GLVRD 127
>gi|48762732 phosphodiesterase 9A isoform h [Homo sapiens]
Length = 507
Score = 38.9 bits (89), Expect = 0.012
Identities = 29/125 (23%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 312 VDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQEEMASRFEIEKRESMFVF 371
++E+ A +++V + E+E L K+ ++++C+ + + +EE+A+R + F
Sbjct: 84 INELKAEVANHLAVLEKRVELEGL--KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSF 141
Query: 372 SSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQDYCWE-DHGYSLVNRLYPDV 430
+ +++TP R V + Y + + PTF V + WE + S + +Y D+
Sbjct: 142 LDNHKKLTPRRDVPTY---PKYLLSPETIEALRKPTFDV--WLWEPNEMLSCLEHMYHDL 196
Query: 431 GQLID 435
G + D
Sbjct: 197 GLVRD 201
>gi|48762726 phosphodiesterase 9A isoform f [Homo sapiens]
Length = 492
Score = 38.9 bits (89), Expect = 0.012
Identities = 29/125 (23%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 312 VDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQEEMASRFEIEKRESMFVF 371
++E+ A +++V + E+E L K+ ++++C+ + + +EE+A+R + F
Sbjct: 69 INELKAEVANHLAVLEKRVELEGL--KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSF 126
Query: 372 SSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQDYCWE-DHGYSLVNRLYPDV 430
+ +++TP R V + Y + + PTF V + WE + S + +Y D+
Sbjct: 127 LDNHKKLTPRRDVPTY---PKYLLSPETIEALRKPTFDV--WLWEPNEMLSCLEHMYHDL 181
Query: 431 GQLID 435
G + D
Sbjct: 182 GLVRD 186
>gi|48762724 phosphodiesterase 9A isoform e [Homo sapiens]
Length = 540
Score = 38.9 bits (89), Expect = 0.012
Identities = 29/125 (23%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 312 VDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQEEMASRFEIEKRESMFVF 371
++E+ A +++V + E+E L K+ ++++C+ + + +EE+A+R + F
Sbjct: 117 INELKAEVANHLAVLEKRVELEGL--KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSF 174
Query: 372 SSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQDYCWE-DHGYSLVNRLYPDV 430
+ +++TP R V + Y + + PTF V + WE + S + +Y D+
Sbjct: 175 LDNHKKLTPRRDVPTY---PKYLLSPETIEALRKPTFDV--WLWEPNEMLSCLEHMYHDL 229
Query: 431 GQLID 435
G + D
Sbjct: 230 GLVRD 234
>gi|48762722 phosphodiesterase 9A isoform d [Homo sapiens]
Length = 465
Score = 38.9 bits (89), Expect = 0.012
Identities = 29/125 (23%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 312 VDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQEEMASRFEIEKRESMFVF 371
++E+ A +++V + E+E L K+ ++++C+ + + +EE+A+R + F
Sbjct: 42 INELKAEVANHLAVLEKRVELEGL--KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSF 99
Query: 372 SSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQDYCWE-DHGYSLVNRLYPDV 430
+ +++TP R V + Y + + PTF V + WE + S + +Y D+
Sbjct: 100 LDNHKKLTPRRDVPTY---PKYLLSPETIEALRKPTFDV--WLWEPNEMLSCLEHMYHDL 154
Query: 431 GQLID 435
G + D
Sbjct: 155 GLVRD 159
>gi|48762720 phosphodiesterase 9A isoform c [Homo sapiens]
Length = 466
Score = 38.9 bits (89), Expect = 0.012
Identities = 29/125 (23%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 312 VDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQEEMASRFEIEKRESMFVF 371
++E+ A +++V + E+E L K+ ++++C+ + + +EE+A+R + F
Sbjct: 43 INELKAEVANHLAVLEKRVELEGL--KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSF 100
Query: 372 SSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQDYCWE-DHGYSLVNRLYPDV 430
+ +++TP R V + Y + + PTF V + WE + S + +Y D+
Sbjct: 101 LDNHKKLTPRRDVPTY---PKYLLSPETIEALRKPTFDV--WLWEPNEMLSCLEHMYHDL 155
Query: 431 GQLID 435
G + D
Sbjct: 156 GLVRD 160
>gi|48762718 phosphodiesterase 9A isoform b [Homo sapiens]
Length = 533
Score = 38.9 bits (89), Expect = 0.012
Identities = 29/125 (23%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 312 VDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQEEMASRFEIEKRESMFVF 371
++E+ A +++V + E+E L K+ ++++C+ + + +EE+A+R + F
Sbjct: 110 INELKAEVANHLAVLEKRVELEGL--KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSF 167
Query: 372 SSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQDYCWE-DHGYSLVNRLYPDV 430
+ +++TP R V + Y + + PTF V + WE + S + +Y D+
Sbjct: 168 LDNHKKLTPRRDVPTY---PKYLLSPETIEALRKPTFDV--WLWEPNEMLSCLEHMYHDL 222
Query: 431 GQLID 435
G + D
Sbjct: 223 GLVRD 227
>gi|4505675 phosphodiesterase 9A isoform a [Homo sapiens]
Length = 593
Score = 38.9 bits (89), Expect = 0.012
Identities = 29/125 (23%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 312 VDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQEEMASRFEIEKRESMFVF 371
++E+ A +++V + E+E L K+ ++++C+ + + +EE+A+R + F
Sbjct: 170 INELKAEVANHLAVLEKRVELEGL--KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSF 227
Query: 372 SSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQDYCWE-DHGYSLVNRLYPDV 430
+ +++TP R V + Y + + PTF V + WE + S + +Y D+
Sbjct: 228 LDNHKKLTPRRDVPTY---PKYLLSPETIEALRKPTFDV--WLWEPNEMLSCLEHMYHDL 282
Query: 431 GQLID 435
G + D
Sbjct: 283 GLVRD 287
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
isoform b [Homo sapiens]
Length = 1176
Score = 32.3 bits (72), Expect = 1.2
Identities = 18/41 (43%), Positives = 25/41 (60%)
Query: 326 SDSFFEVEALMEKMRQLQECRDEEEASQEEMASRFEIEKRE 366
SDS EVEAL E++ + +E +EEE +EE E E+ E
Sbjct: 285 SDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDE 325
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
isoform a [Homo sapiens]
Length = 1210
Score = 32.3 bits (72), Expect = 1.2
Identities = 18/41 (43%), Positives = 25/41 (60%)
Query: 326 SDSFFEVEALMEKMRQLQECRDEEEASQEEMASRFEIEKRE 366
SDS EVEAL E++ + +E +EEE +EE E E+ E
Sbjct: 285 SDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDE 325
>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
sapiens]
Length = 1483
Score = 31.6 bits (70), Expect = 2.0
Identities = 33/134 (24%), Positives = 55/134 (41%), Gaps = 6/134 (4%)
Query: 22 ETALENIRQTILRKTEYLRSV-KETPHRPSDGLSNTESSDGLNKLLAHLLMLSKRCPFKD 80
E E + + + K L V +E + SDG ++ SSD N K K+
Sbjct: 123 EVGKEKMLKVKIVKIHPLEKVDEEATEKKSDGACDSPSSDKENSSQIAQDHQKKETVVKE 182
Query: 81 VREKSEFILKSIQELGIRIPRPLGQG-----PSRFIPEKEILQVGSEDAQMHALFADSFA 135
+ E I + ++P L +G P +F+P K +++ +ED + + ADS
Sbjct: 183 DEGRRESINDRARRSPRKLPTSLKKGERKWAPPKFLPHKYDVKLQNEDKIISNVPADSLI 242
Query: 136 ALGRLDNITLVMVF 149
R N +V F
Sbjct: 243 RTERPPNKEIVRYF 256
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 31.6 bits (70), Expect = 2.0
Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 12/93 (12%)
Query: 331 EVEALMEKMRQLQECRDEEEASQEEMA-----SRFEIEKRESMFVFSSDDE-------EV 378
E + + K Q Q+ + ++EA + E+ ++ E+EK+ES D E E+
Sbjct: 489 EQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKETSAKRGKEI 548
Query: 379 TPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQ 411
T + S+ +TS K G PT +Q
Sbjct: 549 TGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQ 581
>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 31.6 bits (70), Expect = 2.0
Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 12/93 (12%)
Query: 331 EVEALMEKMRQLQECRDEEEASQEEMA-----SRFEIEKRESMFVFSSDDE-------EV 378
E + + K Q Q+ + ++EA + E+ ++ E+EK+ES D E E+
Sbjct: 489 EQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKETSAKRGKEI 548
Query: 379 TPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQ 411
T + S+ +TS K G PT +Q
Sbjct: 549 TGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQ 581
>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 31.6 bits (70), Expect = 2.0
Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 12/93 (12%)
Query: 331 EVEALMEKMRQLQECRDEEEASQEEMA-----SRFEIEKRESMFVFSSDDE-------EV 378
E + + K Q Q+ + ++EA + E+ ++ E+EK+ES D E E+
Sbjct: 489 EQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKETSAKRGKEI 548
Query: 379 TPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQ 411
T + S+ +TS K G PT +Q
Sbjct: 549 TGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQ 581
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 31.2 bits (69), Expect = 2.6
Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 3/92 (3%)
Query: 295 PSVSNYCICDITNGNHSVDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQE 354
PS S D + +E E +DS E E +E+M++ QE DEEE +E
Sbjct: 428 PSASRAETDDEDDEESDEEEEEEEEEEEEEATDS--EEEEDLEQMQEGQE-DDEEEDEEE 484
Query: 355 EMASRFEIEKRESMFVFSSDDEEVTPARAVSR 386
E A+ + +K + S+++ + P + +SR
Sbjct: 485 EAAAGKDGDKSPMSSLQISNEKNLEPGKQISR 516
>gi|215422388 death-domain associated protein isoform a [Homo
sapiens]
Length = 740
Score = 31.2 bits (69), Expect = 2.6
Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 3/92 (3%)
Query: 295 PSVSNYCICDITNGNHSVDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQE 354
PS S D + +E E +DS E E +E+M++ QE DEEE +E
Sbjct: 428 PSASRAETDDEDDEESDEEEEEEEEEEEEEATDS--EEEEDLEQMQEGQE-DDEEEDEEE 484
Query: 355 EMASRFEIEKRESMFVFSSDDEEVTPARAVSR 386
E A+ + +K + S+++ + P + +SR
Sbjct: 485 EAAAGKDGDKSPMSSLQISNEKNLEPGKQISR 516
>gi|215422366 death-domain associated protein isoform b [Homo
sapiens]
Length = 752
Score = 31.2 bits (69), Expect = 2.6
Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 3/92 (3%)
Query: 295 PSVSNYCICDITNGNHSVDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQE 354
PS S D + +E E +DS E E +E+M++ QE DEEE +E
Sbjct: 440 PSASRAETDDEDDEESDEEEEEEEEEEEEEATDS--EEEEDLEQMQEGQE-DDEEEDEEE 496
Query: 355 EMASRFEIEKRESMFVFSSDDEEVTPARAVSR 386
E A+ + +K + S+++ + P + +SR
Sbjct: 497 EAAAGKDGDKSPMSSLQISNEKNLEPGKQISR 528
>gi|50428935 BPY2 interacting protein 1 [Homo sapiens]
Length = 1059
Score = 31.2 bits (69), Expect = 2.6
Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Query: 83 EKSEFILKSIQELGIRIPRPLGQGPSRFIPEKEILQVGSEDAQMHALFADSFAALGRLDN 142
+++E L + +LGI P PL +GP P ++G M+ L S A L +
Sbjct: 353 DEAELALSLLAQLGIT-PLPLSRGPVPAKPTVLFEKMGVGRLDMYVLHPPSAGAERTLAS 411
Query: 143 ITLVMVFHP 151
+ ++V+HP
Sbjct: 412 VCALLVWHP 420
>gi|82830424 gon-4-like isoform a [Homo sapiens]
Length = 2240
Score = 31.2 bits (69), Expect = 2.6
Identities = 36/115 (31%), Positives = 47/115 (40%), Gaps = 15/115 (13%)
Query: 277 GCGISPEIHCDGGHTFRPPSVSNYCICDITNGNHSVDEMPVNSAENVSVSDSFFEVEALM 336
G + PE GG P D+T DEM S E+V S E++ M
Sbjct: 1443 GTPVGPET---GGEKNGPEEEEEEDFDDLTQDEE--DEMSSASEESVL---SVPELQETM 1494
Query: 337 EKM-------RQLQECRDEEEASQEEMASRFEIEKRESMFVFSSDDEEVTPARAV 384
EK+ R QE EEE SQEE + E E+ E+ + S E+ AV
Sbjct: 1495 EKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTDEAV 1549
>gi|24308265 methyltransferase like 14 [Homo sapiens]
Length = 456
Score = 30.4 bits (67), Expect = 4.4
Identities = 16/60 (26%), Positives = 29/60 (48%)
Query: 341 QLQECRDEEEASQEEMASRFEIEKRESMFVFSSDDEEVTPARAVSRHFEDTSYGYKDFSR 400
+++E +DE E Q+E +E E + F + + P +HF DT + ++F R
Sbjct: 76 KMEEYKDELEMQQDEENLPYEEEIYKDSSTFLKGTQSLNPHNDYCQHFVDTGHRPQNFIR 135
>gi|55749531 splicing factor 3B subunit 2 [Homo sapiens]
Length = 895
Score = 30.4 bits (67), Expect = 4.4
Identities = 18/49 (36%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query: 331 EVEALMEKMRQLQECRDEEEASQEEMASRFEIEKRESMFVFSSDDEEVT 379
++ +EK+ QL+E R EE SQ+E E + R S+ +S+ EE T
Sbjct: 268 KIPQALEKILQLKESRQEEMNSQQE-EEEMETDARSSLGQSASETEEDT 315
>gi|4759140 sodium/hydrogen exchanger regulatory factor 1 [Homo
sapiens]
Length = 358
Score = 30.0 bits (66), Expect = 5.7
Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 14/79 (17%)
Query: 22 ETALENIRQTILRK-----TEYLRSVKETPHRPSDGLSNTESSD---------GLNKLLA 67
E ALE+ R ++R +E L S P + S S+T SSD + K A
Sbjct: 275 EAALESPRPALVRSASSDTSEELNSQDSPPKQDSTAPSSTSSSDPILDFNISLAMAKERA 334
Query: 68 HLLMLSKRCPFKDVREKSE 86
H SKR P D +K+E
Sbjct: 335 HQKRSSKRAPQMDWSKKNE 353
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,985,608
Number of Sequences: 37866
Number of extensions: 944482
Number of successful extensions: 2963
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 2912
Number of HSP's gapped (non-prelim): 49
length of query: 551
length of database: 18,247,518
effective HSP length: 107
effective length of query: 444
effective length of database: 14,195,856
effective search space: 6302960064
effective search space used: 6302960064
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.