Search of human proteins with 75813618

Search of human proteins with 75813618

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens]
         (327 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens]           674   0.0  
gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens]           661   0.0  
gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens]           661   0.0  
gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens]            661   0.0  
gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens]           519   e-147
gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens]           517   e-147
gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens]          517   e-147
gi|122937199 protein phosphatase 1B-like [Homo sapiens]               263   2e-70
gi|4505999 protein phosphatase 1G [Homo sapiens]                      126   2e-29
gi|29826282 protein phosphatase 1G [Homo sapiens]                     126   2e-29
gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens]   126   3e-29
gi|13540531 integrin-linked kinase-associated protein phosphatas...   113   2e-25
gi|30089948 protein phosphatase 1E [Homo sapiens]                     103   2e-22
gi|167466276 protein phosphatase 1K (PP2C domain containing) [Ho...   101   8e-22
gi|7661862 protein phosphatase 1F [Homo sapiens]                       98   9e-21
gi|4505997 protein phosphatase 1D [Homo sapiens]                       86   3e-17
gi|29558099 protein phosphatase 1B isoform 3 [Homo sapiens]            69   4e-12
gi|149944715 protein phosphatase 1H (PP2C domain containing) [Ho...    59   5e-09
gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo...    57   2e-08
gi|171460934 protein phosphatase 1M isoform b [Homo sapiens]           55   9e-08
gi|171460932 protein phosphatase 1M isoform a [Homo sapiens]           55   9e-08
gi|65506328 protein phosphatase 1J (PP2C domain containing) [Hom...    53   4e-07
gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit ...    50   4e-06
gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit...    50   4e-06
gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit...    50   4e-06
gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit...    50   4e-06
gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit...    50   4e-06
gi|37221175 PH domain and leucine rich repeat protein phosphatas...    48   1e-05
gi|65301141 PH domain and leucine rich repeat protein phosphatas...    32   1.0  
gi|190194403 ATP/GTP binding protein-like 4 [Homo sapiens]             31   1.7  

>gi|75813618 protein phosphatase 1B isoform 4 [Homo sapiens]
          Length = 327

 Score =  674 bits (1738), Expect = 0.0
 Identities = 327/327 (100%), Positives = 327/327 (100%)

Query: 1   MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60
           MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD
Sbjct: 1   MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60

Query: 61  GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120
           GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF
Sbjct: 61  GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120

Query: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180
           SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI
Sbjct: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180

Query: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL 240
           QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL
Sbjct: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL 240

Query: 241 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK 300
           ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK
Sbjct: 241 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK 300

Query: 301 VSDEAVKKDSELDKHLESRVEGKTNAF 327
           VSDEAVKKDSELDKHLESRVEGKTNAF
Sbjct: 301 VSDEAVKKDSELDKHLESRVEGKTNAF 327


>gi|75813620 protein phosphatase 1B isoform 5 [Homo sapiens]
          Length = 380

 Score =  661 bits (1706), Expect = 0.0
 Identities = 321/321 (100%), Positives = 321/321 (100%)

Query: 1   MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60
           MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD
Sbjct: 1   MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60

Query: 61  GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120
           GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF
Sbjct: 61  GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120

Query: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180
           SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI
Sbjct: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180

Query: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL 240
           QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL
Sbjct: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL 240

Query: 241 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK 300
           ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK
Sbjct: 241 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK 300

Query: 301 VSDEAVKKDSELDKHLESRVE 321
           VSDEAVKKDSELDKHLESRVE
Sbjct: 301 VSDEAVKKDSELDKHLESRVE 321


>gi|29558022 protein phosphatase 1B isoform 2 [Homo sapiens]
          Length = 387

 Score =  661 bits (1706), Expect = 0.0
 Identities = 321/321 (100%), Positives = 321/321 (100%)

Query: 1   MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60
           MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD
Sbjct: 1   MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60

Query: 61  GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120
           GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF
Sbjct: 61  GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120

Query: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180
           SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI
Sbjct: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180

Query: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL 240
           QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL
Sbjct: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL 240

Query: 241 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK 300
           ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK
Sbjct: 241 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK 300

Query: 301 VSDEAVKKDSELDKHLESRVE 321
           VSDEAVKKDSELDKHLESRVE
Sbjct: 301 VSDEAVKKDSELDKHLESRVE 321


>gi|4505995 protein phosphatase 1B isoform 1 [Homo sapiens]
          Length = 479

 Score =  661 bits (1706), Expect = 0.0
 Identities = 321/321 (100%), Positives = 321/321 (100%)

Query: 1   MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60
           MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD
Sbjct: 1   MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60

Query: 61  GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120
           GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF
Sbjct: 61  GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120

Query: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180
           SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI
Sbjct: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180

Query: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL 240
           QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL
Sbjct: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL 240

Query: 241 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK 300
           ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK
Sbjct: 241 ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK 300

Query: 301 VSDEAVKKDSELDKHLESRVE 321
           VSDEAVKKDSELDKHLESRVE
Sbjct: 301 VSDEAVKKDSELDKHLESRVE 321


>gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens]
          Length = 324

 Score =  519 bits (1337), Expect = e-147
 Identities = 254/323 (78%), Positives = 285/323 (88%), Gaps = 6/323 (1%)

Query: 1   MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60
           MGAFLDKPK EKHNA G GNGLRYGLSSMQGWRVEMEDAHTAV+G+P GLE WSFFAVYD
Sbjct: 1   MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 60

Query: 61  GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120
           GHAGS+VA YC  HLL+HIT N+DF+     GSA   SVENVKNGIRTGFL+IDE+MR  
Sbjct: 61  GHAGSQVAKYCCEHLLDHITNNQDFK-----GSAGAPSVENVKNGIRTGFLEIDEHMRVM 115

Query: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180
           S+ ++G DRSGSTAVGV+ISP+H YFINCGDSR +L RN +V F TQDHKP NP EKERI
Sbjct: 116 SEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERI 175

Query: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEE-DEFII 239
           QNAGGSVMIQRVNGSLAVSRALGD+DYKCV GKGPTEQLVSPEPEV++I R+EE D+FII
Sbjct: 176 QNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFII 235

Query: 240 LACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAP 299
           LACDGIWDVM NEELC++V+SRLEV+DDLE VCN VVDTCL+KGSRDNMS++L+CF NAP
Sbjct: 236 LACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAP 295

Query: 300 KVSDEAVKKDSELDKHLESRVEG 322
           KVS EAVKK++ELDK+LE RVEG
Sbjct: 296 KVSPEAVKKEAELDKYLECRVEG 318


>gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens]
          Length = 382

 Score =  517 bits (1331), Expect = e-147
 Identities = 253/322 (78%), Positives = 284/322 (88%), Gaps = 6/322 (1%)

Query: 1   MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60
           MGAFLDKPK EKHNA G GNGLRYGLSSMQGWRVEMEDAHTAV+G+P GLE WSFFAVYD
Sbjct: 1   MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 60

Query: 61  GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120
           GHAGS+VA YC  HLL+HIT N+DF+     GSA   SVENVKNGIRTGFL+IDE+MR  
Sbjct: 61  GHAGSQVAKYCCEHLLDHITNNQDFK-----GSAGAPSVENVKNGIRTGFLEIDEHMRVM 115

Query: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180
           S+ ++G DRSGSTAVGV+ISP+H YFINCGDSR +L RN +V F TQDHKP NP EKERI
Sbjct: 116 SEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERI 175

Query: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEE-DEFII 239
           QNAGGSVMIQRVNGSLAVSRALGD+DYKCV GKGPTEQLVSPEPEV++I R+EE D+FII
Sbjct: 176 QNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFII 235

Query: 240 LACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAP 299
           LACDGIWDVM NEELC++V+SRLEV+DDLE VCN VVDTCL+KGSRDNMS++L+CF NAP
Sbjct: 236 LACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAP 295

Query: 300 KVSDEAVKKDSELDKHLESRVE 321
           KVS EAVKK++ELDK+LE RVE
Sbjct: 296 KVSPEAVKKEAELDKYLECRVE 317


>gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens]
          Length = 455

 Score =  517 bits (1331), Expect = e-147
 Identities = 253/322 (78%), Positives = 284/322 (88%), Gaps = 6/322 (1%)

Query: 1   MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD 60
           MGAFLDKPK EKHNA G GNGLRYGLSSMQGWRVEMEDAHTAV+G+P GLE WSFFAVYD
Sbjct: 74  MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYD 133

Query: 61  GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF 120
           GHAGS+VA YC  HLL+HIT N+DF+     GSA   SVENVKNGIRTGFL+IDE+MR  
Sbjct: 134 GHAGSQVAKYCCEHLLDHITNNQDFK-----GSAGAPSVENVKNGIRTGFLEIDEHMRVM 188

Query: 121 SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI 180
           S+ ++G DRSGSTAVGV+ISP+H YFINCGDSR +L RN +V F TQDHKP NP EKERI
Sbjct: 189 SEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERI 248

Query: 181 QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEE-DEFII 239
           QNAGGSVMIQRVNGSLAVSRALGD+DYKCV GKGPTEQLVSPEPEV++I R+EE D+FII
Sbjct: 249 QNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFII 308

Query: 240 LACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAP 299
           LACDGIWDVM NEELC++V+SRLEV+DDLE VCN VVDTCL+KGSRDNMS++L+CF NAP
Sbjct: 309 LACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAP 368

Query: 300 KVSDEAVKKDSELDKHLESRVE 321
           KVS EAVKK++ELDK+LE RVE
Sbjct: 369 KVSPEAVKKEAELDKYLECRVE 390


>gi|122937199 protein phosphatase 1B-like [Homo sapiens]
          Length = 430

 Score =  263 bits (672), Expect = 2e-70
 Identities = 141/308 (45%), Positives = 189/308 (61%), Gaps = 12/308 (3%)

Query: 13  HNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSRVANYCS 72
           H    A  GLR+G S+ QGWR  MEDAH   + +P     W+ FAV DGH G+R A + +
Sbjct: 56  HGGAEASGGLRFGASAAQGWRARMEDAHCTWLSLPGLPPGWALFAVLDGHGGARAARFGA 115

Query: 73  THLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNFSDLRNGMDRSGS 132
            HL  H+      +  G   S      E V+  +R  FL  DE +R+   L   ++  G 
Sbjct: 116 RHLPGHV-----LQELGPEPS----EPEGVREALRRAFLSADERLRS---LWPRVETGGC 163

Query: 133 TAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQRV 192
           TAV +++SP+ +Y  +CGDSRAVL R G V FST+DH+P  PRE+ERI  AGG++  +RV
Sbjct: 164 TAVVLLVSPRFLYLAHCGDSRAVLSRAGAVAFSTEDHRPLRPRERERIHAAGGTIRRRRV 223

Query: 193 NGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNE 252
            GSLAVSRALGD+ YK   G+ P  QLVS EPEV  + R  EDEF++LA DG+WD +S  
Sbjct: 224 EGSLAVSRALGDFTYKEAPGRPPELQLVSAEPEVAALARQAEDEFMLLASDGVWDTVSGA 283

Query: 253 ELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPKVSDEAVKKDSEL 312
            L   V SRL +    E +C  ++DTCL KGS DNM+ +LVCF  AP+ S+EA++++  L
Sbjct: 284 ALAGLVASRLRLGLAPELLCAQLLDTCLCKGSLDNMTCILVCFPGAPRPSEEAIRRELAL 343

Query: 313 DKHLESRV 320
           D  L  R+
Sbjct: 344 DAALGCRI 351


>gi|4505999 protein phosphatase 1G [Homo sapiens]
          Length = 546

 Score =  126 bits (317), Expect = 2e-29
 Identities = 70/197 (35%), Positives = 116/197 (58%), Gaps = 15/197 (7%)

Query: 130 SGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMI 189
           SG+TAV  +I  K +   N GDSR V+   G+    + DHKP +  E  RI+NAGG V +
Sbjct: 327 SGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTM 386

Query: 190 Q-RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDV 248
             RVNG L +SRA+GD+ YK      P EQ++S  P++  +   ++ EF+++ACDGIW+V
Sbjct: 387 DGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGIWNV 446

Query: 249 MSNEELCEYVKSRLEVSDD------LENVCNWVVDTCLHKGSR------DNMSIVLVCFS 296
           MS++E+ ++++S++   D+      L ++   ++D CL   +       DNM+ +++CF 
Sbjct: 447 MSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFK 506

Query: 297 --NAPKVSDEAVKKDSE 311
             N  ++  E+ K+  E
Sbjct: 507 PRNTAELQPESGKRKLE 523



 Score = 75.1 bits (183), Expect = 8e-14
 Identities = 44/99 (44%), Positives = 57/99 (57%), Gaps = 7/99 (7%)

Query: 1  MGAFLDKPKTEKHNAHGAGNG---LRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFA 57
          MGA+L +P T K +  G G     L YG S+MQGWRV MEDAH     IP    + + F+
Sbjct: 1  MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNC---IPELDSETAMFS 57

Query: 58 VYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALE 96
          VYDGH G  VA YC+ +L + I   + ++  GK   ALE
Sbjct: 58 VYDGHGGEEVALYCAKYLPDIIKDQKAYK-EGKLQKALE 95


>gi|29826282 protein phosphatase 1G [Homo sapiens]
          Length = 546

 Score =  126 bits (317), Expect = 2e-29
 Identities = 70/197 (35%), Positives = 116/197 (58%), Gaps = 15/197 (7%)

Query: 130 SGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMI 189
           SG+TAV  +I  K +   N GDSR V+   G+    + DHKP +  E  RI+NAGG V +
Sbjct: 327 SGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTM 386

Query: 190 Q-RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDV 248
             RVNG L +SRA+GD+ YK      P EQ++S  P++  +   ++ EF+++ACDGIW+V
Sbjct: 387 DGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGIWNV 446

Query: 249 MSNEELCEYVKSRLEVSDD------LENVCNWVVDTCLHKGSR------DNMSIVLVCFS 296
           MS++E+ ++++S++   D+      L ++   ++D CL   +       DNM+ +++CF 
Sbjct: 447 MSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFK 506

Query: 297 --NAPKVSDEAVKKDSE 311
             N  ++  E+ K+  E
Sbjct: 507 PRNTAELQPESGKRKLE 523



 Score = 75.1 bits (183), Expect = 8e-14
 Identities = 44/99 (44%), Positives = 57/99 (57%), Gaps = 7/99 (7%)

Query: 1  MGAFLDKPKTEKHNAHGAGNG---LRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFA 57
          MGA+L +P T K +  G G     L YG S+MQGWRV MEDAH     IP    + + F+
Sbjct: 1  MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNC---IPELDSETAMFS 57

Query: 58 VYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALE 96
          VYDGH G  VA YC+ +L + I   + ++  GK   ALE
Sbjct: 58 VYDGHGGEEVALYCAKYLPDIIKDQKAYK-EGKLQKALE 95


>gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens]
          Length = 360

 Score =  126 bits (316), Expect = 3e-29
 Identities = 89/282 (31%), Positives = 140/282 (49%), Gaps = 23/282 (8%)

Query: 28  SMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRA 87
           S+QG R  MED    +  + +     S F ++DGH G   A Y  + L E +  +     
Sbjct: 97  SIQGRRDHMEDRFEVLTDLANKTHP-SIFGIFDGHGGETAAEYVKSRLPEALKQHLQDYE 155

Query: 88  AGKSGSALELSVENVKNGIRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFI 147
             K  S L     + +  +    L ID  M     L    D +G+T +  ++S K +   
Sbjct: 156 KDKENSVL-----SYQTILEQQILSIDREM--LEKLTVSYDEAGTTCLIALLSDKDLTVA 208

Query: 148 NCGDSRAVLY-RNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQ---RVNGSLAVSRALG 203
           N GDSR VL  ++G     + DHKP   +E++RI+ AGG +      RV G LA+SR+LG
Sbjct: 209 NVGDSRGVLCDKDGNAIPLSHDHKPYQLKERKRIKRAGGFISFNGSWRVQGILAMSRSLG 268

Query: 204 DYDYKCVDGKGPTEQLVSPEPEVYEI-LRAEEDEFIILACDGIWDVMSNEELCEYVKSRL 262
           DY  K ++       +V P+P++    L   + EF+ILA DG+WD  SNEE   ++K RL
Sbjct: 269 DYPLKNLN-------VVIPDPDILTFDLDKLQPEFMILASDGLWDAFSNEEAVRFIKERL 321

Query: 263 EVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPKVSDE 304
              D+       +V    ++G  DN+++++V F N+ K  ++
Sbjct: 322 ---DEPHFGAKSIVLQSFYRGCPDNITVMVVKFRNSSKTEEQ 360


>gi|13540531 integrin-linked kinase-associated protein phosphatase
           2C [Homo sapiens]
          Length = 392

 Score =  113 bits (283), Expect = 2e-25
 Identities = 88/299 (29%), Positives = 138/299 (46%), Gaps = 42/299 (14%)

Query: 21  GLRYGLSSMQGWRVEMEDAHTAVVGIPHG-------LEDWSFFAVYDGHAGSRVANYCST 73
           GL+  ++  +G R EM+DAH  +  I          +   S+FAV+DGH G R + + + 
Sbjct: 106 GLKGYVAERKGEREEMQDAHVILNDITEECRPPSSLITRVSYFAVFDGHGGIRASKFAAQ 165

Query: 74  HLLEHITTNEDFRAAGKSGSALELSVEN-VKNGIRTGFLKIDEYMRNFSDLRNGMDRSGS 132
           +L +++          K      +SVE  VK  +   F   DE     +  +    + GS
Sbjct: 166 NLHQNLIR--------KFPKGDVISVEKTVKRCLLDTFKHTDEEFLKQASSQKPAWKDGS 217

Query: 133 TAVGVMISPKHIYFINCGDSRAVLYRNGQ------VCFSTQDHKPCNPREKERIQNAGGS 186
           TA  V+     +Y  N GDSRA+L R  +          +++H P    E+ RIQ AGG+
Sbjct: 218 TATCVLAVDNILYIANLGDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQKAGGN 277

Query: 187 VMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIW 246
           V   RV G L VSR++GD  YK           V+  P++        D FI+LACDG++
Sbjct: 278 VRDGRVLGVLEVSRSIGDGQYKRCG--------VTSVPDIRRCQLTPNDRFILLACDGLF 329

Query: 247 DVMSNEELCEYVKSRLE------------VSDDLENVCNWVVDTCLHKGSRDNMSIVLV 293
            V + EE   ++ S LE                 E  CN + +  + +GS DN+++++V
Sbjct: 330 KVFTPEEAVNFILSCLEDEKIQTREGKSAADARYEAACNRLANKAVQRGSADNVTVMVV 388


>gi|30089948 protein phosphatase 1E [Homo sapiens]
          Length = 755

 Score =  103 bits (258), Expect = 2e-22
 Identities = 91/315 (28%), Positives = 142/315 (45%), Gaps = 42/315 (13%)

Query: 26  LSSMQGWRVEMEDAHTAV--VGIPHGLEDW---SFFAVYDGHAGSRVANYCSTHLLEHIT 80
           + +++  R +MED H  +    +   LED    ++FAV+DGH G   A Y S HL  ++ 
Sbjct: 234 IHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYASIHLHVNLV 293

Query: 81  TNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMIS 140
             E F               +    +   F   DE  R          R G+T V   I 
Sbjct: 294 RQEMFP-------------HDPAEALCRAFRVTDE--RFVQKAARESLRCGTTGVVTFIR 338

Query: 141 PKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVM---IQRVNGSLA 197
              ++    GDS+ +L R GQ     + HKP    EK+RI+  GG V+     RVNGSL+
Sbjct: 339 GNMLHVAWVGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVVWFGAWRVNGSLS 398

Query: 198 VSRALGDYDYK---CVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEEL 254
           VSRA+GD ++K   C D    +  L   E            +++ILACDG +D ++ +E 
Sbjct: 399 VSRAIGDAEHKPYICGDADSASTVLDGTE------------DYLILACDGFYDTVNPDEA 446

Query: 255 CEYVKSRL-EVSDDLENVCNWVVDTCLHKGSRDNMSIVLVC---FSNAPKVSDEAVKKDS 310
            + V   L E + D   V + +V +    GS DN+++++V     + A  VS+E+   ++
Sbjct: 447 VKVVSDHLKENNGDSSMVAHKLVASARDAGSSDNITVIVVFLRDMNKAVNVSEESDWTEN 506

Query: 311 ELDKHLESRVEGKTN 325
                 E   + K N
Sbjct: 507 SFQGGQEDGGDDKEN 521


>gi|167466276 protein phosphatase 1K (PP2C domain containing) [Homo
           sapiens]
          Length = 372

 Score =  101 bits (252), Expect = 8e-22
 Identities = 85/280 (30%), Positives = 131/280 (46%), Gaps = 38/280 (13%)

Query: 25  GLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNED 84
           G +S  G R E ED            ++  +FAVYDGH G   A++C TH+ + I     
Sbjct: 96  GCASQIGKRKENEDRFD----FAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMD--- 148

Query: 85  FRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNFSDLRNGMD--RSGSTA-VGVMISP 141
                     L    +N++  +   FL+ID+   + + L        SG+TA V ++   
Sbjct: 149 ----------LLPKEKNLETLLTLAFLEIDKAFSSHARLSADATLLTSGTTATVALLRDG 198

Query: 142 KHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGG-----SVMIQRVNGSL 196
             +   + GDSRA+L R G+    T DH P    EKERI+  GG     S+    VNG L
Sbjct: 199 IELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRL 258

Query: 197 AVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEI-LRAEEDEFIILACDGIWDVMSNEELC 255
           A++R++GD D K           V  EPE   I L   +D F++L  DGI  +++++E+C
Sbjct: 259 AMTRSIGDLDLKTSG--------VIAEPETKRIKLHHADDSFLVLTTDGINFMVNSQEIC 310

Query: 256 EYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCF 295
           ++V        D     + V +  +  G+ DN + V+V F
Sbjct: 311 DFVNQ----CHDPNEAAHAVTEQAIQYGTEDNSTAVVVPF 346


>gi|7661862 protein phosphatase 1F [Homo sapiens]
          Length = 454

 Score = 98.2 bits (243), Expect = 9e-21
 Identities = 78/278 (28%), Positives = 132/278 (47%), Gaps = 35/278 (12%)

Query: 26  LSSMQGWRVEMEDAHTAVVGIPH--GLED---WSFFAVYDGHAGSRVANYCSTHLLEHIT 80
           + +++  R +MED H ++       GL D    ++FAV+DGH G   A Y + H+  +  
Sbjct: 159 IHAIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAA 218

Query: 81  TNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDE-YMRNFSDLRNGMDRSGSTAVGVMI 139
              +                + +  +R  F + D+ ++R     R    +SG+T V  +I
Sbjct: 219 RQPELPT-------------DPEGALREAFRRTDQMFLRKAKRERL---QSGTTGVCALI 262

Query: 140 SPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVM---IQRVNGSL 196
           +   ++    GDS+ +L + GQV    + H+P    EK RI+  GG V      RVNG+L
Sbjct: 263 AGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTL 322

Query: 197 AVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCE 256
           AVSRA+GD   K           VS E +         +++++LACDG +DV+ ++E+  
Sbjct: 323 AVSRAIGDVFQK---------PYVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVG 373

Query: 257 YVKSRLEVSDDLE-NVCNWVVDTCLHKGSRDNMSIVLV 293
            V+S L         V   +V     +GS DN+++++V
Sbjct: 374 LVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVV 411


>gi|4505997 protein phosphatase 1D [Homo sapiens]
          Length = 605

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 87/302 (28%), Positives = 137/302 (45%), Gaps = 69/302 (22%)

Query: 54  SFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFL-- 111
           +FFAV DGH G   A +   HL   I   + F ++  +          V   IR GFL  
Sbjct: 99  AFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPA---------KVCAAIRKGFLAC 149

Query: 112 ------KIDEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNG----- 160
                 K+ E+ +  + L +    SG+TA  V+I    +Y  + GDS  VL         
Sbjct: 150 HLAMWKKLAEWPKTMTGLPS---TSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDD 206

Query: 161 --QVCFSTQDHKPCNPREKERIQNAGGSVM----IQRV---------NGS---------- 195
             +    TQDHKP  P+E+ERI+  GGSVM    + RV         NG           
Sbjct: 207 FVRAVEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQI 266

Query: 196 --LAVSRALGD-YDYKCVDGKGPTEQLVSPEPEV-YEILRAEEDEFIILACDGIWDVMSN 251
             LAV+RALGD + Y    G    E +VSPEP+     L  ++ ++IIL  DG+W+++  
Sbjct: 267 PFLAVARALGDLWSYDFFSG----EFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPP 322

Query: 252 EELCEYVKSRLE----VSDDLENVCNWVVDTCLHKGSR-----DNMSIVLVCFSNAPKVS 302
           ++     + + E    + +  ++    +V+  L +  +     DN S +++C S  P+V 
Sbjct: 323 QDAISMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQRMLRADNTSAIVICIS--PEVD 380

Query: 303 DE 304
           ++
Sbjct: 381 NQ 382


>gi|29558099 protein phosphatase 1B isoform 3 [Homo sapiens]
          Length = 192

 Score = 69.3 bits (168), Expect = 4e-12
 Identities = 34/34 (100%), Positives = 34/34 (100%)

Query: 288 MSIVLVCFSNAPKVSDEAVKKDSELDKHLESRVE 321
           MSIVLVCFSNAPKVSDEAVKKDSELDKHLESRVE
Sbjct: 1   MSIVLVCFSNAPKVSDEAVKKDSELDKHLESRVE 34


>gi|149944715 protein phosphatase 1H (PP2C domain containing) [Homo
           sapiens]
          Length = 514

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 51/193 (26%), Positives = 80/193 (41%), Gaps = 57/193 (29%)

Query: 131 GSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREK------------- 177
           G TA+ V+     +Y  N GDSRA++ RNG++   + +  P   R++             
Sbjct: 268 GCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLG 327

Query: 178 ---------ERIQNAG-GSVMIQR------------------------------VNGSLA 197
                     R+Q    G  M+ R                              V  ++ 
Sbjct: 328 NEFTHLEFPRRVQRKELGKKMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMATIG 387

Query: 198 VSRALGDYDYKCVDGKGPTEQLVSPEPEV--YEILRAE--EDEFIILACDGIWDVMSNEE 253
           V+R LGD+D K  D     +  +S  PEV  Y++ + +   D+ +ILA DG+WDV+SNEE
Sbjct: 388 VTRGLGDHDLKVHDSNIYIKPFLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSNEE 447

Query: 254 LCEYVKSRLEVSD 266
           + E +   L   D
Sbjct: 448 VAEAITQFLPNCD 460


>gi|41349497 pyruvate dehydrogenase phosphatase isoenzyme 2 [Homo
           sapiens]
          Length = 529

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 58/188 (30%), Positives = 83/188 (44%), Gaps = 39/188 (20%)

Query: 114 DEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVL---YRNGQ-VCFS-TQD 168
           DE  RN S     +  SG+TA    +   H++  N GD RA+L     NG   C   T+D
Sbjct: 252 DEVTRNLS---LQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRD 308

Query: 169 HKPCNPREKERIQNAGGS------VMIQRVNGSLAVSRALGDYDYK--------CVDGKG 214
           H   N  E  R++           +M  R+ G L   RA GD   K         ++   
Sbjct: 309 HNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGF 368

Query: 215 PTEQL---------------VSPEPEV-YEILRAEEDEFIILACDGIWDVMSNEELCEYV 258
            TE L               ++ EPEV Y  LR + D+F++LA DG+WD++SNE++   V
Sbjct: 369 NTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQ-DKFLVLASDGLWDMLSNEDVVRLV 427

Query: 259 KSRLEVSD 266
              L  +D
Sbjct: 428 VGHLAEAD 435


>gi|171460934 protein phosphatase 1M isoform b [Homo sapiens]
          Length = 247

 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 31/105 (29%), Positives = 60/105 (57%), Gaps = 6/105 (5%)

Query: 191 RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEI----LRAEEDEFIILACDGIW 246
           R+ G+LAVSR LGD+  + +D     +  +   P+V  +    L  +ED+ +++A DG+W
Sbjct: 116 RLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLW 175

Query: 247 DVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLH--KGSRDNMS 289
           DV+SNE++   V+S L  + +  +  + +    +H  +G  D+++
Sbjct: 176 DVLSNEQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGKEDSLT 220


>gi|171460932 protein phosphatase 1M isoform a [Homo sapiens]
          Length = 298

 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 31/105 (29%), Positives = 60/105 (57%), Gaps = 6/105 (5%)

Query: 191 RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEI----LRAEEDEFIILACDGIW 246
           R+ G+LAVSR LGD+  + +D     +  +   P+V  +    L  +ED+ +++A DG+W
Sbjct: 167 RLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSVPQVTVLDVDQLELQEDDVVVMATDGLW 226

Query: 247 DVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLH--KGSRDNMS 289
           DV+SNE++   V+S L  + +  +  + +    +H  +G  D+++
Sbjct: 227 DVLSNEQVAWLVRSFLPGNQEDPHRFSKLAQMLIHSTQGKEDSLT 271


>gi|65506328 protein phosphatase 1J (PP2C domain containing) [Homo
           sapiens]
          Length = 505

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 65/295 (22%), Positives = 108/295 (36%), Gaps = 95/295 (32%)

Query: 55  FFAVYDGHAGSRVANYCSTHLLEHIT----------------------------TNEDFR 86
           ++ ++DGHAG   A   S  L  HI                             +++   
Sbjct: 153 YWGLFDGHAGGGAAEMASRLLHRHIREQLKDLVEILQDPSPPPLCLPTTPGTPDSSDPSH 212

Query: 87  AAGKSG---SALELSVENVKNG-IRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMISPK 142
             G      S  E+S E++  G +   F  +DE M    + R      G  A+ V+    
Sbjct: 213 LLGPQSCWSSQKEVSHESLVVGAVENAFQLMDEQMAR--ERRGHQVEGGCCALVVIYLLG 270

Query: 143 HIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAG------------------ 184
            +Y  N GDSRA++ RNG++   +++  P    E++R+Q  G                  
Sbjct: 271 KVYVANAGDSRAIIVRNGEIIPMSREFTP--ETERQRLQLLGFLKPELLGSEFTHLEFPR 328

Query: 185 -------GSVMIQR------------------------------VNGSLAVSRALGDYDY 207
                  G  M+ R                              V  ++ V+R LGD+  
Sbjct: 329 RVLPKELGQRMLYRDQNMTGWAYKKIELEDLRFPLVCGEGKKARVMATIGVTRGLGDHSL 388

Query: 208 KCVDGKGPTEQLVS--PEPEVYEILRAEE--DEFIILACDGIWDVMSNEELCEYV 258
           K      P +  +S  PE  VY++ + E   D+ ++L  DG+WDV ++ E+   V
Sbjct: 389 KVCSSTLPIKPFLSCFPEVRVYDLTQYEHCPDDVLVLGTDGLWDVTTDCEVAATV 443


>gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit 1
           isoform 3 precursor [Homo sapiens]
          Length = 537

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 50/165 (30%), Positives = 71/165 (43%), Gaps = 37/165 (22%)

Query: 130 SGSTAVGVMISPKHIYFINCGDSRAVL---YRNGQVCFST--QDHKPCNPREKERIQ--- 181
           SG+TA    +    ++  N GDSRA+L     +G     T   DH   N RE ER++   
Sbjct: 270 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 329

Query: 182 ---NAGGSVMIQRVNGSLAVSRALGDYDYKC-------VDGKGP---------------- 215
               A   V   R+ G L   RA GD  +K        V   GP                
Sbjct: 330 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 389

Query: 216 -TEQLVSPEPEV-YEILRAEEDEFIILACDGIWDVMSNEELCEYV 258
            T   ++ EPEV Y  LR + D+F++LA DG+W+ M  +++   V
Sbjct: 390 HTPPYLTAEPEVTYHRLRPQ-DKFLVLATDGLWETMHRQDVVRIV 433


>gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit 1
           isoform 3 precursor [Homo sapiens]
          Length = 537

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 50/165 (30%), Positives = 71/165 (43%), Gaps = 37/165 (22%)

Query: 130 SGSTAVGVMISPKHIYFINCGDSRAVL---YRNGQVCFST--QDHKPCNPREKERIQ--- 181
           SG+TA    +    ++  N GDSRA+L     +G     T   DH   N RE ER++   
Sbjct: 270 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 329

Query: 182 ---NAGGSVMIQRVNGSLAVSRALGDYDYKC-------VDGKGP---------------- 215
               A   V   R+ G L   RA GD  +K        V   GP                
Sbjct: 330 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 389

Query: 216 -TEQLVSPEPEV-YEILRAEEDEFIILACDGIWDVMSNEELCEYV 258
            T   ++ EPEV Y  LR + D+F++LA DG+W+ M  +++   V
Sbjct: 390 HTPPYLTAEPEVTYHRLRPQ-DKFLVLATDGLWETMHRQDVVRIV 433


>gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit 1
           isoform 2 [Homo sapiens]
          Length = 562

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 50/165 (30%), Positives = 71/165 (43%), Gaps = 37/165 (22%)

Query: 130 SGSTAVGVMISPKHIYFINCGDSRAVL---YRNGQVCFST--QDHKPCNPREKERIQ--- 181
           SG+TA    +    ++  N GDSRA+L     +G     T   DH   N RE ER++   
Sbjct: 295 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 354

Query: 182 ---NAGGSVMIQRVNGSLAVSRALGDYDYKC-------VDGKGP---------------- 215
               A   V   R+ G L   RA GD  +K        V   GP                
Sbjct: 355 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 414

Query: 216 -TEQLVSPEPEV-YEILRAEEDEFIILACDGIWDVMSNEELCEYV 258
            T   ++ EPEV Y  LR + D+F++LA DG+W+ M  +++   V
Sbjct: 415 HTPPYLTAEPEVTYHRLRPQ-DKFLVLATDGLWETMHRQDVVRIV 458


>gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit 1
           isoform 2 [Homo sapiens]
          Length = 562

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 50/165 (30%), Positives = 71/165 (43%), Gaps = 37/165 (22%)

Query: 130 SGSTAVGVMISPKHIYFINCGDSRAVL---YRNGQVCFST--QDHKPCNPREKERIQ--- 181
           SG+TA    +    ++  N GDSRA+L     +G     T   DH   N RE ER++   
Sbjct: 295 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 354

Query: 182 ---NAGGSVMIQRVNGSLAVSRALGDYDYKC-------VDGKGP---------------- 215
               A   V   R+ G L   RA GD  +K        V   GP                
Sbjct: 355 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 414

Query: 216 -TEQLVSPEPEV-YEILRAEEDEFIILACDGIWDVMSNEELCEYV 258
            T   ++ EPEV Y  LR + D+F++LA DG+W+ M  +++   V
Sbjct: 415 HTPPYLTAEPEVTYHRLRPQ-DKFLVLATDGLWETMHRQDVVRIV 458


>gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit 1
           isoform 1 [Homo sapiens]
          Length = 596

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 50/165 (30%), Positives = 71/165 (43%), Gaps = 37/165 (22%)

Query: 130 SGSTAVGVMISPKHIYFINCGDSRAVL---YRNGQVCFST--QDHKPCNPREKERIQ--- 181
           SG+TA    +    ++  N GDSRA+L     +G     T   DH   N RE ER++   
Sbjct: 329 SGATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEH 388

Query: 182 ---NAGGSVMIQRVNGSLAVSRALGDYDYKC-------VDGKGP---------------- 215
               A   V   R+ G L   RA GD  +K        V   GP                
Sbjct: 389 PKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNY 448

Query: 216 -TEQLVSPEPEV-YEILRAEEDEFIILACDGIWDVMSNEELCEYV 258
            T   ++ EPEV Y  LR + D+F++LA DG+W+ M  +++   V
Sbjct: 449 HTPPYLTAEPEVTYHRLRPQ-DKFLVLATDGLWETMHRQDVVRIV 492


>gi|37221175 PH domain and leucine rich repeat protein phosphatase
           [Homo sapiens]
          Length = 1205

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 42/150 (28%), Positives = 65/150 (43%), Gaps = 14/150 (9%)

Query: 148 NCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQ-RVNGSLAVSRALGDYD 206
           N G  + VL RNG+    ++ +      E +RI+     +    +VNG    +R LG Y 
Sbjct: 775 NVGKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITEDGKVNGVTESTRILG-YT 833

Query: 207 YKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEYVKSRLEVSD 266
           +            V P P V  +L   +DEF IL   G+WD +S EE  E V++  +   
Sbjct: 834 F--------LHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPDALA 885

Query: 267 DLENVCNWVVDTCLHKGSRDNMSIVLVCFS 296
             + +C          G  D++S V+V  S
Sbjct: 886 AAKKLCT----LAQSYGCHDSISAVVVQLS 911


>gi|65301141 PH domain and leucine rich repeat protein
            phosphatase-like [Homo sapiens]
          Length = 1323

 Score = 31.6 bits (70), Expect = 1.0
 Identities = 35/149 (23%), Positives = 61/149 (40%), Gaps = 17/149 (11%)

Query: 148  NCGDSRAVLYRNGQ-VCFSTQDHKPCNPREKERIQNAGGSVMIQ-RVNGSLAVSRALG-D 204
            N G  +AVL R G+ V  S       +P E +R+++    +    +VNG    +R LG  
Sbjct: 897  NVGTCQAVLCRGGKPVPLSKVFSLEQDPEEAQRVKDQKAIITEDNKVNGVTCCTRMLGCT 956

Query: 205  YDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEELCEYVKSRLEV 264
            Y Y  +           P+P +       +DE +IL    +W+ +S  E    V+   + 
Sbjct: 957  YLYPWI----------LPKPHISSTPLTIQDELLILGNKALWEHLSYTEAVNAVRHVQDP 1006

Query: 265  SDDLENVCNWVVDTCLHKGSRDNMSIVLV 293
                + +C          G +DN+  ++V
Sbjct: 1007 LAAAKKLCT----LAQSYGCQDNVGAMVV 1031


>gi|190194403 ATP/GTP binding protein-like 4 [Homo sapiens]
          Length = 503

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 4/74 (5%)

Query: 98  SVENVKNGIRTGFLKIDEYMRNFSDLRNGMD---RSGSTAVGVMISPKHIYFINCGDSRA 154
           +VENVK   R  F  I  + +  S  R+GM    +S S      + PK++Y+  C D R 
Sbjct: 86  TVENVKESQRVIF-NIVNFSKTKSLYRDGMAPMVKSTSRPKWQRLPPKNVYYYRCPDHRK 144

Query: 155 VLYRNGQVCFSTQD 168
               +   CF  ++
Sbjct: 145 NYVMSFAFCFDREE 158


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,839,298
Number of Sequences: 37866
Number of extensions: 566754
Number of successful extensions: 1226
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1133
Number of HSP's gapped (non-prelim): 57
length of query: 327
length of database: 18,247,518
effective HSP length: 103
effective length of query: 224
effective length of database: 14,347,320
effective search space: 3213799680
effective search space used: 3213799680
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.