Guide to the Human Genome
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Search of human proteins with 75677608

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|75677608 serine incorporator 4 [Homo sapiens]
         (274 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|75677608 serine incorporator 4 [Homo sapiens]                      571   e-163
gi|30172548 developmentally regulated protein TPO1 [Homo sapiens]     108   7e-24
gi|24308213 serine incorporator 1 [Homo sapiens]                      104   7e-23
gi|71834872 tumor differentially expressed 2-like [Homo sapiens]       99   5e-21
gi|39812106 tumor differentially expressed protein 1 [Homo sapiens]    96   3e-20
gi|5803193 tumor differentially expressed protein 1 [Homo sapiens]     96   3e-20
gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]              30   3.0  
gi|169204908 PREDICTED: similar to Thyroid hormone receptor inte...    29   3.9  
gi|169205597 PREDICTED: similar to Thyroid hormone receptor inte...    29   3.9  
gi|169203883 PREDICTED: hypothetical protein [Homo sapiens]            29   3.9  
gi|60460881 zinc finger, SWIM-type containing 1 [Homo sapiens]         29   5.1  
gi|46397390 pogo transposable element with ZNF domain isoform 1 ...    28   6.6  
gi|46397394 pogo transposable element with ZNF domain isoform 2 ...    28   6.6  
gi|224493919 zinc finger and SCAN domain containing 18 isoform 2...    28   8.6  
gi|224493912 zinc finger and SCAN domain containing 18 isoform 3...    28   8.6  
gi|229093316 phospholipase B domain containing 2 isoform 1 precu...    28   8.6  
gi|229091322 phospholipase B domain containing 2 isoform 2 precu...    28   8.6  
gi|226371704 zinc finger and SCAN domain containing 18 isoform 3...    28   8.6  
gi|4557329 fas ligand [Homo sapiens]                                   28   8.6  
gi|224493905 zinc finger and SCAN domain containing 18 isoform 1...    28   8.6  

>gi|75677608 serine incorporator 4 [Homo sapiens]
          Length = 274

 Score =  571 bits (1472), Expect = e-163
 Identities = 274/274 (100%), Positives = 274/274 (100%)

Query: 1   MSISSQHGITLASVEALHSSYCSWCLLQLLPIPGTRTEQPRSGLLQASVISCYIMYLTFS 60
           MSISSQHGITLASVEALHSSYCSWCLLQLLPIPGTRTEQPRSGLLQASVISCYIMYLTFS
Sbjct: 1   MSISSQHGITLASVEALHSSYCSWCLLQLLPIPGTRTEQPRSGLLQASVISCYIMYLTFS 60

Query: 61  ALSSRPPERVILQGQNHTLCLPGLSKMEPQTPDISLAMLSASIMYACVLFACNEASYLAE 120
           ALSSRPPERVILQGQNHTLCLPGLSKMEPQTPDISLAMLSASIMYACVLFACNEASYLAE
Sbjct: 61  ALSSRPPERVILQGQNHTLCLPGLSKMEPQTPDISLAMLSASIMYACVLFACNEASYLAE 120

Query: 121 VFGPLWIVKVYSYEFQKPSLCFCCPETVEADKGQRGGAARPADQETPPAPPVQVQHLSYN 180
           VFGPLWIVKVYSYEFQKPSLCFCCPETVEADKGQRGGAARPADQETPPAPPVQVQHLSYN
Sbjct: 121 VFGPLWIVKVYSYEFQKPSLCFCCPETVEADKGQRGGAARPADQETPPAPPVQVQHLSYN 180

Query: 181 YSAFHFVFFLASLYVMVTLTNWFSYEGAELEKTFIKGSWATFWVKVASCWACVLLYLGLL 240
           YSAFHFVFFLASLYVMVTLTNWFSYEGAELEKTFIKGSWATFWVKVASCWACVLLYLGLL
Sbjct: 181 YSAFHFVFFLASLYVMVTLTNWFSYEGAELEKTFIKGSWATFWVKVASCWACVLLYLGLL 240

Query: 241 LAPLCWPPTQKPQPLILRRRRHRIISPDNKYPPV 274
           LAPLCWPPTQKPQPLILRRRRHRIISPDNKYPPV
Sbjct: 241 LAPLCWPPTQKPQPLILRRRRHRIISPDNKYPPV 274


>gi|30172548 developmentally regulated protein TPO1 [Homo sapiens]
          Length = 423

 Score =  108 bits (269), Expect = 7e-24
 Identities = 68/182 (37%), Positives = 104/182 (57%), Gaps = 11/182 (6%)

Query: 26  LLQLLPI-PGTRTEQPRSGLLQASVISCYIMYLTFSALSSRPPERVILQ-GQNHTLCLPG 83
           L+ L+ I P  +  QP SGLLQ+ VISCY+ YLTFSALSS+P E V+ + G+N T+C+P 
Sbjct: 242 LISLVAISPWVQNRQPHSGLLQSGVISCYVTYLTFSALSSKPAEVVLDEHGKNVTICVPD 301

Query: 84  LSKMEPQTPDISLAMLSASIMYACVLFACNEASYLAEVFGPLWIVKVYSYEFQKPSLCFC 143
             + +    +  + +L  S++  C+L++C  ++  +         +  + E +    CFC
Sbjct: 302 FGQ-DLYRDENLVTILGTSLLIGCILYSCLTSTTRSS--SDALQGRYAAPELEIARCCFC 358

Query: 144 CPETVEADKGQRGGAARPADQETPPAPPVQVQHLSYNYSAFHFVFFLASLYVMVTLTNWF 203
                E  + Q+ G      +E P     + +   Y YS FHFVFFLASLYVM+T+TNWF
Sbjct: 359 FSPGGEDTEEQQPG------KEGPRVIYDEKKGTVYIYSYFHFVFFLASLYVMMTVTNWF 412

Query: 204 SY 205
           ++
Sbjct: 413 NH 414


>gi|24308213 serine incorporator 1 [Homo sapiens]
          Length = 453

 Score =  104 bits (260), Expect = 7e-23
 Identities = 71/220 (32%), Positives = 111/220 (50%), Gaps = 30/220 (13%)

Query: 32  IPGTRTEQPRSGLLQASVISCYIMYLTFSALSSRP-----PERVILQGQNHTLCLPGLSK 86
           +P  +  QPRSGLLQ+SVI+ Y MYLT+SA+++ P     P  + + G N T  +P    
Sbjct: 249 LPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNEPETNCNPSLLSIIGYNTTSTVP---- 304

Query: 87  MEPQTPDI--SLAMLSASIMYACVLFACNEASYLAEVFGPLWIVKVYSYEFQKPSLCFCC 144
            E Q+     +  ++   +   CV ++    S  ++V   L +    S            
Sbjct: 305 KEGQSVQWWHAQGIIGLILFLLCVFYSSIRTSNNSQV-NKLTLTSDES------------ 351

Query: 145 PETVEADKGQRGGAARPADQETPPAPPVQVQHLSYNYSAFHFVFFLASLYVMVTLTNWFS 204
             T+  D G R   +     +   A   +   ++Y+YS FHF+ FLASLY+M+TLTNW+ 
Sbjct: 352 --TLIEDGGARSDGSLEDGDDVHRAVDNERDGVTYSYSFFHFMLFLASLYIMMTLTNWYR 409

Query: 205 YEGAELEKTFIKGSWATFWVKVASCWACVLLYLGLLLAPL 244
           YE +      +K  W   WVK++S W  ++LY+  L+APL
Sbjct: 410 YEPSR----EMKSQWTAVWVKISSSWIGIVLYVWTLVAPL 445


>gi|71834872 tumor differentially expressed 2-like [Homo sapiens]
          Length = 455

 Score = 98.6 bits (244), Expect = 5e-21
 Identities = 80/236 (33%), Positives = 119/236 (50%), Gaps = 36/236 (15%)

Query: 16  ALHSSYCSWCLLQLLPIPGTRTEQPRSGLLQASVISCYIMYLTFSALSSRPPER----VI 71
           +L+ ++C  C+     +P  +  QP SGLLQASVI+ Y M++T+SALSS P ++    + 
Sbjct: 241 SLNLTFCV-CVSIAAVLPKVQDAQPNSGLLQASVITLYTMFVTWSALSSIPEQKCNPHLP 299

Query: 72  LQGQNHTLCLPGLSKMEPQTPDISLAMLSASIMYACVLFACNEASYLAEVFGPLWIVKVY 131
            Q  N T+ + G    E Q  D + +++   I   C LF    +S   +V   +   +  
Sbjct: 300 TQLGNETV-VAGPEGYETQWWD-APSIVGLIIFLLCTLFISLRSSDHRQVNSLMQTEE-- 355

Query: 132 SYEFQKPSLCFCCPETVEADKGQRGGAA---RPADQETPPAPPVQVQHLSYNYSAFHFVF 188
                       CP  ++A + Q+  AA   R  D E           ++Y+YS FHF  
Sbjct: 356 ------------CPPMLDATQQQQQVAACEGRAFDNEQ--------DGVTYSYSFFHFCL 395

Query: 189 FLASLYVMVTLTNWFSYEGAELEKTFIKGSWATFWVKVASCWACVLLYLGLLLAPL 244
            LASL+VM+TLTNW  Y+  E  K     +W   WVK+ + WA +LLYL  L+APL
Sbjct: 396 VLASLHVMMTLTNW--YKPGETRKMI--STWTAVWVKICASWAGLLLYLWTLVAPL 447


>gi|39812106 tumor differentially expressed protein 1 [Homo sapiens]
          Length = 473

 Score = 95.9 bits (237), Expect = 3e-20
 Identities = 69/232 (29%), Positives = 105/232 (45%), Gaps = 44/232 (18%)

Query: 33  PGTRTEQPRSGLLQASVISCYIMYLTFSALSSRPPERV--------------ILQGQNHT 78
           P  +  QPRSGLLQ+S+I+ Y MYLT+SA+S+ P                   L   N T
Sbjct: 258 PKIQEHQPRSGLLQSSLITLYTMYLTWSAMSNEPDRSCNPNLMSFITRITAPTLAPGNST 317

Query: 79  LCLPGLSKMEPQTPDISLAMLSAS------IMYACVLFACNEASYLAEVFGPLWIVKVYS 132
             +P      P  P  S ++L +       +   C+L++    S  ++V           
Sbjct: 318 AVVP-----TPTPPSKSGSLLDSDNFIGLFVFVLCLLYSSIRTSTNSQV----------- 361

Query: 133 YEFQKPSLCFCCPETVEADKGQRGGAARPADQETPPAPPVQVQHLSYNYSAFHFVFFLAS 192
                  L     ++V        GA+   D +   A   + + + Y+YS FH +  LAS
Sbjct: 362 -----DKLTLSGSDSVILGDTTTSGASDEEDGQPRRAVDNEKEGVQYSYSLFHLMLCLAS 416

Query: 193 LYVMVTLTNWFSYEGAELEKTFIKGSWATFWVKVASCWACVLLYLGLLLAPL 244
           LY+M+TLT+W+S +      T     W   WVK++S W C+LLY+  L+APL
Sbjct: 417 LYIMMTLTSWYSPDAKFQSMT---SKWPAVWVKISSSWVCLLLYVWTLVAPL 465


>gi|5803193 tumor differentially expressed protein 1 [Homo sapiens]
          Length = 473

 Score = 95.9 bits (237), Expect = 3e-20
 Identities = 69/232 (29%), Positives = 105/232 (45%), Gaps = 44/232 (18%)

Query: 33  PGTRTEQPRSGLLQASVISCYIMYLTFSALSSRPPERV--------------ILQGQNHT 78
           P  +  QPRSGLLQ+S+I+ Y MYLT+SA+S+ P                   L   N T
Sbjct: 258 PKIQEHQPRSGLLQSSLITLYTMYLTWSAMSNEPDRSCNPNLMSFITRITAPTLAPGNST 317

Query: 79  LCLPGLSKMEPQTPDISLAMLSAS------IMYACVLFACNEASYLAEVFGPLWIVKVYS 132
             +P      P  P  S ++L +       +   C+L++    S  ++V           
Sbjct: 318 AVVP-----TPTPPSKSGSLLDSDNFIGLFVFVLCLLYSSIRTSTNSQV----------- 361

Query: 133 YEFQKPSLCFCCPETVEADKGQRGGAARPADQETPPAPPVQVQHLSYNYSAFHFVFFLAS 192
                  L     ++V        GA+   D +   A   + + + Y+YS FH +  LAS
Sbjct: 362 -----DKLTLSGSDSVILGDTTTSGASDEEDGQPRRAVDNEKEGVQYSYSLFHLMLCLAS 416

Query: 193 LYVMVTLTNWFSYEGAELEKTFIKGSWATFWVKVASCWACVLLYLGLLLAPL 244
           LY+M+TLT+W+S +      T     W   WVK++S W C+LLY+  L+APL
Sbjct: 417 LYIMMTLTSWYSPDAKFQSMT---SKWPAVWVKISSSWVCLLLYVWTLVAPL 465


>gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]
          Length = 234

 Score = 29.6 bits (65), Expect = 3.0
 Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 3/55 (5%)

Query: 136 QKPSLCFCCPETV-EADKGQRGGAARPADQETPPAPPVQV--QHLSYNYSAFHFV 187
           QKP++   C ET  E  +GQR G+   + Q+    PP +   +H+   Y+ F+ V
Sbjct: 96  QKPTVTSVCSETSQELAEGQRRGSQGDSKQQNGKIPPKRPPRKHIVERYTEFYHV 150


>gi|169204908 PREDICTED: similar to Thyroid hormone receptor
           interactor 11 [Homo sapiens]
          Length = 352

 Score = 29.3 bits (64), Expect = 3.9
 Identities = 15/62 (24%), Positives = 29/62 (46%), Gaps = 1/62 (1%)

Query: 32  IPGTRTEQPRSGLLQASVISCYIMYLTFSALSSRPPERVILQGQNHTLCLPGLSKMEPQT 91
           +P T     +  +L +S   C++ +L   + SS PP ++ +      L  PG  K++   
Sbjct: 216 VPNTPLRPNQQSVLNSSFSECFVKFLETESHSSVPPPKLSVHDMK-PLESPGRRKLDTNA 274

Query: 92  PD 93
           P+
Sbjct: 275 PE 276


>gi|169205597 PREDICTED: similar to Thyroid hormone receptor
           interactor 11 [Homo sapiens]
          Length = 352

 Score = 29.3 bits (64), Expect = 3.9
 Identities = 15/62 (24%), Positives = 29/62 (46%), Gaps = 1/62 (1%)

Query: 32  IPGTRTEQPRSGLLQASVISCYIMYLTFSALSSRPPERVILQGQNHTLCLPGLSKMEPQT 91
           +P T     +  +L +S   C++ +L   + SS PP ++ +      L  PG  K++   
Sbjct: 216 VPNTPLRPNQQSVLNSSFSECFVKFLETESHSSVPPPKLSVHDMK-PLESPGRRKLDTNA 274

Query: 92  PD 93
           P+
Sbjct: 275 PE 276


>gi|169203883 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 352

 Score = 29.3 bits (64), Expect = 3.9
 Identities = 15/62 (24%), Positives = 29/62 (46%), Gaps = 1/62 (1%)

Query: 32  IPGTRTEQPRSGLLQASVISCYIMYLTFSALSSRPPERVILQGQNHTLCLPGLSKMEPQT 91
           +P T     +  +L +S   C++ +L   + SS PP ++ +      L  PG  K++   
Sbjct: 216 VPNTPLRPNQQSVLNSSFSECFVKFLETESHSSVPPPKLSVHDMK-PLESPGRRKLDTNA 274

Query: 92  PD 93
           P+
Sbjct: 275 PE 276


>gi|60460881 zinc finger, SWIM-type containing 1 [Homo sapiens]
          Length = 485

 Score = 28.9 bits (63), Expect = 5.1
 Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 1/52 (1%)

Query: 30  LPIPGTRTEQPRSGLLQASVISCYIMYLTFSALS-SRPPERVILQGQNHTLC 80
           LP+P    E P + +L ++   C  +   F  LS  RP ER++L     T+C
Sbjct: 152 LPLPILAMEFPTAEVLLSAFHICKFLQAKFYQLSLERPVERLLLTSLQSTMC 203


>gi|46397390 pogo transposable element with ZNF domain isoform 1
           [Homo sapiens]
          Length = 1410

 Score = 28.5 bits (62), Expect = 6.6
 Identities = 12/33 (36%), Positives = 18/33 (54%), Gaps = 2/33 (6%)

Query: 140 LCFCCPETVEADKGQRGGAARPA--DQETPPAP 170
           +C+CCPE VE  K  +   + P+      PP+P
Sbjct: 394 MCYCCPEMVEYQKKGKSLDSEPSVPSAAKPPSP 426


>gi|46397394 pogo transposable element with ZNF domain isoform 2
           [Homo sapiens]
          Length = 1357

 Score = 28.5 bits (62), Expect = 6.6
 Identities = 12/33 (36%), Positives = 18/33 (54%), Gaps = 2/33 (6%)

Query: 140 LCFCCPETVEADKGQRGGAARPA--DQETPPAP 170
           +C+CCPE VE  K  +   + P+      PP+P
Sbjct: 341 MCYCCPEMVEYQKKGKSLDSEPSVPSAAKPPSP 373


>gi|224493919 zinc finger and SCAN domain containing 18 isoform 2
           [Homo sapiens]
          Length = 374

 Score = 28.1 bits (61), Expect = 8.6
 Identities = 14/28 (50%), Positives = 15/28 (53%), Gaps = 1/28 (3%)

Query: 145 PETVEADKGQR-GGAARPADQETPPAPP 171
           P T EA  G R GG     + E PPAPP
Sbjct: 343 PSTREAQAGARAGGPPESVEGEAPPAPP 370


>gi|224493912 zinc finger and SCAN domain containing 18 isoform 3
           [Homo sapiens]
          Length = 510

 Score = 28.1 bits (61), Expect = 8.6
 Identities = 14/28 (50%), Positives = 15/28 (53%), Gaps = 1/28 (3%)

Query: 145 PETVEADKGQR-GGAARPADQETPPAPP 171
           P T EA  G R GG     + E PPAPP
Sbjct: 479 PSTREAQAGARAGGPPESVEGEAPPAPP 506


>gi|229093316 phospholipase B domain containing 2 isoform 1
           precursor [Homo sapiens]
          Length = 589

 Score = 28.1 bits (61), Expect = 8.6
 Identities = 14/38 (36%), Positives = 21/38 (55%), Gaps = 1/38 (2%)

Query: 178 SYNYSAFHFVFFLASLYVMVT-LTNWFSYEGAELEKTF 214
           SYN  +F  VF  + L  +V    +WFSY+G+   + F
Sbjct: 425 SYNIPSFETVFNASGLQALVAQYGDWFSYDGSPRAQIF 462


>gi|229091322 phospholipase B domain containing 2 isoform 2
           precursor [Homo sapiens]
          Length = 557

 Score = 28.1 bits (61), Expect = 8.6
 Identities = 14/38 (36%), Positives = 21/38 (55%), Gaps = 1/38 (2%)

Query: 178 SYNYSAFHFVFFLASLYVMVT-LTNWFSYEGAELEKTF 214
           SYN  +F  VF  + L  +V    +WFSY+G+   + F
Sbjct: 393 SYNIPSFETVFNASGLQALVAQYGDWFSYDGSPRAQIF 430


>gi|226371704 zinc finger and SCAN domain containing 18 isoform 3
           [Homo sapiens]
          Length = 510

 Score = 28.1 bits (61), Expect = 8.6
 Identities = 14/28 (50%), Positives = 15/28 (53%), Gaps = 1/28 (3%)

Query: 145 PETVEADKGQR-GGAARPADQETPPAPP 171
           P T EA  G R GG     + E PPAPP
Sbjct: 479 PSTREAQAGARAGGPPESVEGEAPPAPP 506


>gi|4557329 fas ligand [Homo sapiens]
          Length = 281

 Score = 28.1 bits (61), Expect = 8.6
 Identities = 14/46 (30%), Positives = 17/46 (36%)

Query: 126 WIVKVYSYEFQKPSLCFCCPETVEADKGQRGGAARPADQETPPAPP 171
           W+    S  +  P     CP +V    GQR     P     PP PP
Sbjct: 14  WVDSSASSPWAPPGTVLPCPTSVPRRPGQRRPPPPPPPPPLPPPPP 59


>gi|224493905 zinc finger and SCAN domain containing 18 isoform 1
           [Homo sapiens]
          Length = 566

 Score = 28.1 bits (61), Expect = 8.6
 Identities = 14/28 (50%), Positives = 15/28 (53%), Gaps = 1/28 (3%)

Query: 145 PETVEADKGQR-GGAARPADQETPPAPP 171
           P T EA  G R GG     + E PPAPP
Sbjct: 535 PSTREAQAGARAGGPPESVEGEAPPAPP 562


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.136    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,210,980
Number of Sequences: 37866
Number of extensions: 559577
Number of successful extensions: 2267
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 2243
Number of HSP's gapped (non-prelim): 30
length of query: 274
length of database: 18,247,518
effective HSP length: 101
effective length of query: 173
effective length of database: 14,423,052
effective search space: 2495187996
effective search space used: 2495187996
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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