Guide to the Human Genome
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Search of human proteins with 72534762

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|72534762 transmembrane protein 150A isoform 1 [Homo sapiens]
         (271 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|72534762 transmembrane protein 150A isoform 1 [Homo sapiens]       557   e-159
gi|23503273 transmembrane protein 150A isoform 2 [Homo sapiens]       362   e-100
gi|148232433 transmembrane protein 150B [Homo sapiens]                117   8e-27
gi|122937458 hypothetical protein LOC441027 [Homo sapiens]            105   4e-23
gi|110825978 DNA-damage regulated autophagy modulator 1 [Homo sa...    69   3e-12
gi|166235182 transmembrane protein 77 [Homo sapiens]                   56   4e-08
gi|110347453 solute carrier family 7 (cationic amino acid transp...    30   2.2  
gi|31742498 unc-84 homolog B [Homo sapiens]                            30   2.9  
gi|42544177 complement component (3d/Epstein Barr virus) recepto...    29   5.0  
gi|54792123 complement component (3d/Epstein Barr virus) recepto...    29   5.0  
gi|126091152 cubilin [Homo sapiens]                                    29   5.0  
gi|169167822 PREDICTED: similar to hCG17429 [Homo sapiens]             28   6.5  
gi|169167904 PREDICTED: similar to hCG17429 [Homo sapiens]             28   6.5  
gi|239742531 PREDICTED: similar to hCG17429 [Homo sapiens]             28   6.5  
gi|28875784 armadillo repeat containing 5 isoform b [Homo sapiens]     28   6.5  
gi|157426856 armadillo repeat containing 5 isoform a [Homo sapiens]    28   6.5  
gi|13540547 solute carrier family 2 member 10 [Homo sapiens]           28   8.5  
gi|198041662 pyrroline-5-carboxylate reductase-like [Homo sapiens]     28   8.5  
gi|157074214 potassium channel, subfamily U, member 1 [Homo sapi...    28   8.5  

>gi|72534762 transmembrane protein 150A isoform 1 [Homo sapiens]
          Length = 271

 Score =  557 bits (1435), Expect = e-159
 Identities = 271/271 (100%), Positives = 271/271 (100%)

Query: 1   MTAWILLPVSLSAFSITGIWTVYAMAVMNHHVCPVENWSYNESCPPDPAEQGGPKTCCTL 60
           MTAWILLPVSLSAFSITGIWTVYAMAVMNHHVCPVENWSYNESCPPDPAEQGGPKTCCTL
Sbjct: 1   MTAWILLPVSLSAFSITGIWTVYAMAVMNHHVCPVENWSYNESCPPDPAEQGGPKTCCTL 60

Query: 61  DDVPLISKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWVNTTALITGCT 120
           DDVPLISKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWVNTTALITGCT
Sbjct: 61  DDVPLISKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWVNTTALITGCT 120

Query: 121 NAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAVAYLRSV 180
           NAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAVAYLRSV
Sbjct: 121 NAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAVAYLRSV 180

Query: 181 LAVIAFITLVLSGVFFVHESSQLQHGAALCEWVCVIDILIFYGTFSYEFGAVSSDTLVAA 240
           LAVIAFITLVLSGVFFVHESSQLQHGAALCEWVCVIDILIFYGTFSYEFGAVSSDTLVAA
Sbjct: 181 LAVIAFITLVLSGVFFVHESSQLQHGAALCEWVCVIDILIFYGTFSYEFGAVSSDTLVAA 240

Query: 241 LQPTPGRACKSSGSSSTSTHLNCAPESIAMI 271
           LQPTPGRACKSSGSSSTSTHLNCAPESIAMI
Sbjct: 241 LQPTPGRACKSSGSSSTSTHLNCAPESIAMI 271


>gi|23503273 transmembrane protein 150A isoform 2 [Homo sapiens]
          Length = 218

 Score =  362 bits (929), Expect = e-100
 Identities = 182/187 (97%), Positives = 182/187 (97%)

Query: 85  MGAFMVALICLLRYGQLLEQSRHSWVNTTALITGCTNAAGLLVVGNFQVDHARSLHYVGA 144
           M    VALICLLRYGQLLEQSRHSWVNTTALITGCTNAAGLLVVGNFQVDHARSLHYVGA
Sbjct: 32  MSPSSVALICLLRYGQLLEQSRHSWVNTTALITGCTNAAGLLVVGNFQVDHARSLHYVGA 91

Query: 145 GVAFPAGLLFVCLHCALSYQGATAPLDLAVAYLRSVLAVIAFITLVLSGVFFVHESSQLQ 204
           GVAFPAGLLFVCLHCALSYQGATAPLDLAVAYLRSVLAVIAFITLVLSGVFFVHESSQLQ
Sbjct: 92  GVAFPAGLLFVCLHCALSYQGATAPLDLAVAYLRSVLAVIAFITLVLSGVFFVHESSQLQ 151

Query: 205 HGAALCEWVCVIDILIFYGTFSYEFGAVSSDTLVAALQPTPGRACKSSGSSSTSTHLNCA 264
           HGAALCEWVCVIDI IFYGTFSYEFGAVSSDTLVAALQPTPGRACKSSGSSSTSTHLNCA
Sbjct: 152 HGAALCEWVCVIDIPIFYGTFSYEFGAVSSDTLVAALQPTPGRACKSSGSSSTSTHLNCA 211

Query: 265 PESIAMI 271
           PESIAMI
Sbjct: 212 PESIAMI 218


>gi|148232433 transmembrane protein 150B [Homo sapiens]
          Length = 233

 Score =  117 bits (294), Expect = 8e-27
 Identities = 80/241 (33%), Positives = 119/241 (49%), Gaps = 31/241 (12%)

Query: 6   LLPVSLSAFSITGIWTVYAMAVMNHHVCPVENWSYNESCPPDPAEQGGPKTCCTLDDVPL 65
           L+PV L+ ++I+G+W V+A+AV N                         +T       P 
Sbjct: 7   LMPVFLAVWAISGVWIVFAIAVTN-------------------------RTVDLSKGFPY 41

Query: 66  ISKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWVNTTALITGCTNAAGL 125
           IS CGS+PP+SC+FS + NMGA + A IC++RY QL +     W N   L TG   A G 
Sbjct: 42  ISICGSFPPQSCIFSQVLNMGAALAAWICIVRYHQLRDWGVRRWPNQLILWTGLLCALGT 101

Query: 126 LVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCAL-SYQGATAPLDLAVAYLRSVLAVI 184
            VVGNFQ  + R  H  GA +AF  G ++  L   L   +    P    +  LR  L + 
Sbjct: 102 SVVGNFQEKNQRPTHLAGAFLAFILGNVYFWLQLLLWRLKRLPQPGAAWIGPLR--LGLC 159

Query: 185 AFITLVLSGVFFVHESSQLQHGAALCEWVCVIDILIFYGTFSYEFGAVSSDTLVAALQPT 244
           +  T+++  +  +H  S L+  +A CEWV  + +   +G  + +F A+ S TL   +QP 
Sbjct: 160 SVCTILIVAMIVLHACS-LRSVSAACEWVVAMLLFALFGLLAVDFSALESCTL--CVQPW 216

Query: 245 P 245
           P
Sbjct: 217 P 217


>gi|122937458 hypothetical protein LOC441027 [Homo sapiens]
          Length = 249

 Score =  105 bits (262), Expect = 4e-23
 Identities = 64/228 (28%), Positives = 112/228 (49%), Gaps = 19/228 (8%)

Query: 2   TAWILLPVSLSAFSITGIWTVYAMAVMNHHVCPVENWSYNESCPPDPAEQGGPKTCCTLD 61
           + W+ LP+  + F+  G+W VY +AV +  + P+ +             + G K      
Sbjct: 7   SVWMFLPLVFTLFTSAGLWIVYFIAVEDDKILPLNS----------AERKPGVK------ 50

Query: 62  DVPLISKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWVNTTALITGCTN 121
             P IS  G  PP SC+FS + NM AF+  ++ +LR+ QL  +  + W+N + L+  C  
Sbjct: 51  HAPYISIAGDDPPASCVFSQVMNMAAFLALVVAVLRFIQLKPKVLNPWLNISGLVALCLA 110

Query: 122 AAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAVAYLRSVL 181
           + G+ ++GNFQ+ +   +H VG  + F  G L   +  AL+ +         V   R +L
Sbjct: 111 SFGMTLLGNFQLTNDEEIHNVGTSLTFGFGTLTCWIQAALTLKVNIKNEGRRVGIPRVIL 170

Query: 182 AVIAFITLVLSGVFFVHESSQLQHGAALCEWVCVIDILIFYGTFSYEF 229
           +    + +VL   +F+  +  +   AA  +W  V+  L ++GTF+ EF
Sbjct: 171 SASITLCVVL---YFILMAQSIHMYAARVQWGLVMCFLSYFGTFAVEF 215


>gi|110825978 DNA-damage regulated autophagy modulator 1 [Homo
           sapiens]
          Length = 238

 Score = 69.3 bits (168), Expect = 3e-12
 Identities = 48/188 (25%), Positives = 88/188 (46%), Gaps = 17/188 (9%)

Query: 63  VPLISKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWVNT-----TALIT 117
           +P IS  G+ PPES +F  + N  AF+ A     RY  + +Q++  + +T      +L+ 
Sbjct: 40  LPYISDTGTTPPESGIFGFMINFSAFLGAATMYTRYKIVQKQNQTCYFSTPVFNLVSLVL 99

Query: 118 GCTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAVAYL 177
           G     G+ +V NFQ      +H  GA +AF  G+++  L   +SY+       L+  ++
Sbjct: 100 GLVGCFGMGIVANFQELAVPVVHDGGALLAFVCGVVYTLLQSIISYKSCPQWNSLSTCHI 159

Query: 178 RSVLAVI---AFITLVLSGVFF--------VHESSQLQH-GAALCEWVCVIDILIFYGTF 225
           R V++ +   A I +++               E   + H  +A+CEW      + ++ TF
Sbjct: 160 RMVISAVSCAAVIPMIVCASLISITKLEWNPREKDYVYHVVSAICEWTVAFGFIFYFLTF 219

Query: 226 SYEFGAVS 233
             +F +V+
Sbjct: 220 IQDFQSVT 227


>gi|166235182 transmembrane protein 77 [Homo sapiens]
          Length = 266

 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 38/125 (30%), Positives = 57/125 (45%), Gaps = 4/125 (3%)

Query: 63  VPLISKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWV----NTTALITG 118
           +P IS  G+  PE CLF  + N+ A +      +RY Q+   S    V    N   L+ G
Sbjct: 40  LPYISDTGTVAPEKCLFGAMLNIAAVLCIATIYVRYKQVHALSPEENVIIKLNKAGLVLG 99

Query: 119 CTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAVAYLR 178
             +  GL +V NFQ     + H  GA + F  G L++ +   LSYQ         V ++R
Sbjct: 100 ILSCLGLSIVANFQKTTLFAAHVSGAVLTFGMGSLYMFVQTILSYQMQPKIHGKQVFWIR 159

Query: 179 SVLAV 183
            +L +
Sbjct: 160 LLLVI 164


>gi|110347453 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 4 [Homo sapiens]
          Length = 635

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 26/102 (25%), Positives = 40/102 (39%), Gaps = 2/102 (1%)

Query: 64  PLISKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWVNTTALITGCTNAA 123
           P +     Y P + +   +G M A  + + C+L +G       H       L+T      
Sbjct: 464 PYLGFLDGYSPGAVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFLL 523

Query: 124 GLLVVGNFQVDHARSLHYVGAGVAFPA--GLLFVCLHCALSY 163
            LLV+G  Q  +   L  +      PA   +L +CL   LSY
Sbjct: 524 SLLVLGAHQQQYREDLFQIPMVPLIPALSIVLNICLMLKLSY 565


>gi|31742498 unc-84 homolog B [Homo sapiens]
          Length = 717

 Score = 29.6 bits (65), Expect = 2.9
 Identities = 14/44 (31%), Positives = 18/44 (40%)

Query: 4   WILLPVSLSAFSITGIWTVYAMAVMNHHVCPVENWSYNESCPPD 47
           W LLP+ L      G W  Y   +   H   V  W+  +S  PD
Sbjct: 215 WFLLPLLLLTCLTYGAWYFYPYGLQTFHPALVSWWAAKDSRRPD 258


>gi|42544177 complement component (3d/Epstein Barr virus) receptor 2
           isoform 2 [Homo sapiens]
          Length = 1033

 Score = 28.9 bits (63), Expect = 5.0
 Identities = 16/45 (35%), Positives = 20/45 (44%), Gaps = 4/45 (8%)

Query: 43  SCPPDPAEQGGPKTCCTLDDVP----LISKCGSYPPESCLFSLIG 83
           +CPP P    G  T  +L+D P    +   C   P     FSLIG
Sbjct: 526 TCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIG 570


>gi|54792123 complement component (3d/Epstein Barr virus) receptor 2
           isoform 1 [Homo sapiens]
          Length = 1092

 Score = 28.9 bits (63), Expect = 5.0
 Identities = 16/45 (35%), Positives = 20/45 (44%), Gaps = 4/45 (8%)

Query: 43  SCPPDPAEQGGPKTCCTLDDVP----LISKCGSYPPESCLFSLIG 83
           +CPP P    G  T  +L+D P    +   C   P     FSLIG
Sbjct: 526 TCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIG 570


>gi|126091152 cubilin [Homo sapiens]
          Length = 3623

 Score = 28.9 bits (63), Expect = 5.0
 Identities = 15/43 (34%), Positives = 22/43 (51%), Gaps = 3/43 (6%)

Query: 39  SYNESCPPDPAEQGGPKTCCTLDDVPLISKCGSYPPESCLFSL 81
           S+ ++CPP     G     CTL D+  +S  G +P  SC  +L
Sbjct: 331 SHCQACPPGYQGDG---RVCTLTDICSVSNGGCHPDASCSSTL 370


>gi|169167822 PREDICTED: similar to hCG17429 [Homo sapiens]
          Length = 353

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 15/38 (39%), Positives = 17/38 (44%), Gaps = 3/38 (7%)

Query: 40 YNESCPPDPAEQGGPKTCC---TLDDVPLISKCGSYPP 74
          +  S PP PA  G P   C   T D  PL S    +PP
Sbjct: 55 HGASSPPKPAACGHPNAPCARDTADPAPLCSLTAFFPP 92


>gi|169167904 PREDICTED: similar to hCG17429 [Homo sapiens]
          Length = 353

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 15/38 (39%), Positives = 17/38 (44%), Gaps = 3/38 (7%)

Query: 40 YNESCPPDPAEQGGPKTCC---TLDDVPLISKCGSYPP 74
          +  S PP PA  G P   C   T D  PL S    +PP
Sbjct: 55 HGASSPPKPAACGHPNAPCARDTADPAPLCSLTAFFPP 92


>gi|239742531 PREDICTED: similar to hCG17429 [Homo sapiens]
          Length = 353

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 15/38 (39%), Positives = 17/38 (44%), Gaps = 3/38 (7%)

Query: 40 YNESCPPDPAEQGGPKTCC---TLDDVPLISKCGSYPP 74
          +  S PP PA  G P   C   T D  PL S    +PP
Sbjct: 55 HGASSPPKPAACGHPNAPCARDTADPAPLCSLTAFFPP 92


>gi|28875784 armadillo repeat containing 5 isoform b [Homo sapiens]
          Length = 725

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 24/82 (29%), Positives = 33/82 (40%), Gaps = 11/82 (13%)

Query: 37  NWSYNESCPPDPAEQGGPKTCCTLDDVPLISKCGSYPPESCLFSLIGNMGAFMVALICLL 96
           +WS  E CPP+P E   P    T    P   +     P + +    G  G    AL+ L 
Sbjct: 475 DWS-PEQCPPEPMEPASPAPTPTSLRAPRTQRTPGRSPAAAIEEPWGREGP---ALLLLS 530

Query: 97  RYGQLLEQSRHSWVNTTALITG 118
           R+ Q  + S        AL+TG
Sbjct: 531 RFSQAPDPS-------GALVTG 545


>gi|157426856 armadillo repeat containing 5 isoform a [Homo sapiens]
          Length = 935

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 24/82 (29%), Positives = 33/82 (40%), Gaps = 11/82 (13%)

Query: 37  NWSYNESCPPDPAEQGGPKTCCTLDDVPLISKCGSYPPESCLFSLIGNMGAFMVALICLL 96
           +WS  E CPP+P E   P    T    P   +     P + +    G  G    AL+ L 
Sbjct: 475 DWS-PEQCPPEPMEPASPAPTPTSLRAPRTQRTPGRSPAAAIEEPWGREGP---ALLLLS 530

Query: 97  RYGQLLEQSRHSWVNTTALITG 118
           R+ Q  + S        AL+TG
Sbjct: 531 RFSQAPDPS-------GALVTG 545


>gi|13540547 solute carrier family 2 member 10 [Homo sapiens]
          Length = 541

 Score = 28.1 bits (61), Expect = 8.5
 Identities = 10/28 (35%), Positives = 17/28 (60%)

Query: 206 GAALCEWVCVIDILIFYGTFSYEFGAVS 233
           G AL  W  ++ +++F   FS+ FG V+
Sbjct: 404 GHALLRWTALLCLMVFVSAFSFGFGPVT 431


>gi|198041662 pyrroline-5-carboxylate reductase-like [Homo sapiens]
          Length = 286

 Score = 28.1 bits (61), Expect = 8.5
 Identities = 44/169 (26%), Positives = 68/169 (40%), Gaps = 25/169 (14%)

Query: 73  PPESCLFSLIGNMGAFMVALICLLRYGQL-LEQSRHSWVNTTALITGCTNAAGLLV-VGN 130
           PP + +  ++ N       L C+++ G + + + RH   + T L+     A G    V  
Sbjct: 127 PPNTRVLRVLPN-------LPCVVQEGAIVMARGRHVGSSETKLLQHLLEACGRCEEVPE 179

Query: 131 FQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAVAYLRSVLAVIAFITLV 190
             VD    L   G+GVAF      VC       +GA     + +    S+   IA  TL+
Sbjct: 180 AYVDIHTGLS--GSGVAF------VCAFSEALAEGA-----VKMGMPSSLAHRIAAQTLL 226

Query: 191 LSGVFFVHESSQLQHGAALCEWVCVIDILIFYGTFSYEFGAVSSDTLVA 239
            +    +HE    QH A L   VC       YG  + E G + + T+ A
Sbjct: 227 GTAKMLLHEG---QHPAQLRSDVCTPGGTTIYGLHALEQGGLRAATMSA 272


>gi|157074214 potassium channel, subfamily U, member 1 [Homo
           sapiens]
          Length = 1149

 Score = 28.1 bits (61), Expect = 8.5
 Identities = 39/173 (22%), Positives = 68/173 (39%), Gaps = 29/173 (16%)

Query: 59  TLDDVPLISKCGSYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQSRHSWVNTTALITG 118
           T +D+P +S          L S +     F   LI LL + +L+ +S   W     +I G
Sbjct: 10  TWEDLPKMSCTTEIQAAFILSSFV----TFFSGLIILLIF-RLIWRSVKKW----QIIKG 60

Query: 119 CTNAAGLLVVGNFQVDHARSLHYVGAGVAFPAGLLFVCLHCALSYQGATAPLDLAVAYLR 178
                 L   G     H RSLH+ G                   ++     L  A  ++ 
Sbjct: 61  TGIILELFTSGTIARSHVRSLHFQG------------------QFRDHIEMLLSAQTFVG 102

Query: 179 SVLAVIAFITLVLS-GVFFVHESSQLQHGAALCEWVCVIDILIFYGTFSYEFG 230
            VL ++ F+  + S  ++F++ +  +   ++  +    ID L+F   FS+ FG
Sbjct: 103 QVLVILVFVLSIGSLIIYFINSADPVGSCSSYEDKTIPID-LVFNAFFSFYFG 154


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.136    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,116,497
Number of Sequences: 37866
Number of extensions: 497633
Number of successful extensions: 1580
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1564
Number of HSP's gapped (non-prelim): 21
length of query: 271
length of database: 18,247,518
effective HSP length: 101
effective length of query: 170
effective length of database: 14,423,052
effective search space: 2451918840
effective search space used: 2451918840
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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