Search of human proteins with 72534720

Search of human proteins with 72534720

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|72534720 IQ motif containing H isoform 1 [Homo sapiens]
         (1027 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|72534720 IQ motif containing H isoform 1 [Homo sapiens]           2068   0.0  
gi|12232475 IQ motif containing H isoform 2 [Homo sapiens]            606   e-173
gi|58331148 matrix metalloproteinase 11 preproprotein [Homo sapi...    35   0.47 
gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens]    34   0.62 
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       33   1.1  
gi|110431348 deleted in colorectal carcinoma [Homo sapiens]            32   2.4  
gi|239745414 PREDICTED: NPIP-like protein 2 isoform 2 [Homo sapi...    32   2.4  
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    31   5.2  
gi|46370073 GRB2-associated binding protein 1 isoform b [Homo sa...    31   5.2  
gi|46370071 GRB2-associated binding protein 1 isoform a [Homo sa...    31   5.2  
gi|239741653 PREDICTED: hypothetical protein XP_002342271 [Homo ...    31   5.2  
gi|157168329 formin 1 [Homo sapiens]                                   31   6.8  
gi|126116596 asp (abnormal spindle)-like, microcephaly associate...    31   6.8  
gi|4501893 actinin, alpha 2 [Homo sapiens]                             31   6.8  
gi|124378039 SEC16 homolog A [Homo sapiens]                            30   8.9  
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        30   8.9  
gi|148833513 RNA binding motif protein 47 isoform a [Homo sapiens]     30   8.9  
gi|148833511 RNA binding motif protein 47 isoform b [Homo sapiens]     30   8.9  
gi|209969832 FAST kinase domains 2 [Homo sapiens]                      30   8.9  
gi|209969830 FAST kinase domains 2 [Homo sapiens]                      30   8.9  
gi|45267832 FAST kinase domains 2 [Homo sapiens]                       30   8.9  
gi|157384986 transducin-like enhancer protein 3 isoform b [Homo ...    30   8.9  
gi|157384984 transducin-like enhancer protein 3 isoform c [Homo ...    30   8.9  
gi|157384982 transducin-like enhancer protein 3 isoform a [Homo ...    30   8.9  
gi|31377705 centrosomal protein 97kDa [Homo sapiens]                   30   8.9  

>gi|72534720 IQ motif containing H isoform 1 [Homo sapiens]
          Length = 1027

 Score = 2068 bits (5358), Expect = 0.0
 Identities = 1027/1027 (100%), Positives = 1027/1027 (100%)

Query: 1    MAQNTENHDPVGSILIQIHEDLYQLKEKLTKFSPEEKGETLDIQSLETAIKRTEVGLRIH 60
            MAQNTENHDPVGSILIQIHEDLYQLKEKLTKFSPEEKGETLDIQSLETAIKRTEVGLRIH
Sbjct: 1    MAQNTENHDPVGSILIQIHEDLYQLKEKLTKFSPEEKGETLDIQSLETAIKRTEVGLRIH 60

Query: 61   IEKYLNVVNQNVLTTSVNDESLYTPQASKWLLPTVIDQKSFIFPQESEGTFWQPQRQHSS 120
            IEKYLNVVNQNVLTTSVNDESLYTPQASKWLLPTVIDQKSFIFPQESEGTFWQPQRQHSS
Sbjct: 61   IEKYLNVVNQNVLTTSVNDESLYTPQASKWLLPTVIDQKSFIFPQESEGTFWQPQRQHSS 120

Query: 121  SLPVFPRAKIKVSKLIKGSNISSLTVLPSSHCTDPYFTPIPVLQADAHKGILSMIERGLI 180
            SLPVFPRAKIKVSKLIKGSNISSLTVLPSSHCTDPYFTPIPVLQADAHKGILSMIERGLI
Sbjct: 121  SLPVFPRAKIKVSKLIKGSNISSLTVLPSSHCTDPYFTPIPVLQADAHKGILSMIERGLI 180

Query: 181  PPTARITFQNPPITPRAAPLHSFDEARKIPTVATFTIPREPPPSPAEVKFFPKKQRSKGK 240
            PPTARITFQNPPITPRAAPLHSFDEARKIPTVATFTIPREPPPSPAEVKFFPKKQRSKGK
Sbjct: 181  PPTARITFQNPPITPRAAPLHSFDEARKIPTVATFTIPREPPPSPAEVKFFPKKQRSKGK 240

Query: 241  SRRSRGHHDRKAMKVKTPLRALKSLWDYDFLIYDGVIDNTAPDFLAFKEHFSLAWGGIFS 300
            SRRSRGHHDRKAMKVKTPLRALKSLWDYDFLIYDGVIDNTAPDFLAFKEHFSLAWGGIFS
Sbjct: 241  SRRSRGHHDRKAMKVKTPLRALKSLWDYDFLIYDGVIDNTAPDFLAFKEHFSLAWGGIFS 300

Query: 301  LLEHVEKFLRNYAIPEVKIKGNNLVALLPEFELTNKLTRYDLLSVLEDPAHVQMLINLPG 360
            LLEHVEKFLRNYAIPEVKIKGNNLVALLPEFELTNKLTRYDLLSVLEDPAHVQMLINLPG
Sbjct: 301  LLEHVEKFLRNYAIPEVKIKGNNLVALLPEFELTNKLTRYDLLSVLEDPAHVQMLINLPG 360

Query: 361  QRYKGQDGNSEAAMKIQATWKCYKARKFFLFYRQQKWASGVIAIAWLLYCHKTRLKKILK 420
            QRYKGQDGNSEAAMKIQATWKCYKARKFFLFYRQQKWASGVIAIAWLLYCHKTRLKKILK
Sbjct: 361  QRYKGQDGNSEAAMKIQATWKCYKARKFFLFYRQQKWASGVIAIAWLLYCHKTRLKKILK 420

Query: 421  ESRQRHLENFRIRAKHLAANWNRIRTSRRTIIHIPSLGYSQPVREHIADFNTQQNMQLGR 480
            ESRQRHLENFRIRAKHLAANWNRIRTSRRTIIHIPSLGYSQPVREHIADFNTQQNMQLGR
Sbjct: 421  ESRQRHLENFRIRAKHLAANWNRIRTSRRTIIHIPSLGYSQPVREHIADFNTQQNMQLGR 480

Query: 481  LCDILDANVNVIYICSHHMNDELVLYYKKILSLHAAVKSGNLEDRSDLQDRFKIITPEAV 540
            LCDILDANVNVIYICSHHMNDELVLYYKKILSLHAAVKSGNLEDRSDLQDRFKIITPEAV
Sbjct: 481  LCDILDANVNVIYICSHHMNDELVLYYKKILSLHAAVKSGNLEDRSDLQDRFKIITPEAV 540

Query: 541  NIFPKHHMCLATHLMYSPKAIKRIKNLIRGTEAYIVSGLLHRDDLAVADMLDIPILGSEP 600
            NIFPKHHMCLATHLMYSPKAIKRIKNLIRGTEAYIVSGLLHRDDLAVADMLDIPILGSEP
Sbjct: 541  NIFPKHHMCLATHLMYSPKAIKRIKNLIRGTEAYIVSGLLHRDDLAVADMLDIPILGSEP 600

Query: 601  ELAHLYSTKSGGKRVFDSANVAVPPGIYDIYSQQQMIEQLSQLITDHLQIQRWLFKMDSE 660
            ELAHLYSTKSGGKRVFDSANVAVPPGIYDIYSQQQMIEQLSQLITDHLQIQRWLFKMDSE
Sbjct: 601  ELAHLYSTKSGGKRVFDSANVAVPPGIYDIYSQQQMIEQLSQLITDHLQIQRWLFKMDSE 660

Query: 661  FRGNGTAFCDIPSYLKCYKWVLKESSRYGLEDWRKKWAQEPALVKISEELAGILAQHAQP 720
            FRGNGTAFCDIPSYLKCYKWVLKESSRYGLEDWRKKWAQEPALVKISEELAGILAQHAQP
Sbjct: 661  FRGNGTAFCDIPSYLKCYKWVLKESSRYGLEDWRKKWAQEPALVKISEELAGILAQHAQP 720

Query: 721  VNEKRFPTWRKFLQTFLSQGGVIEAFPPADNVTNLTVDMLIEPNGKISVLSTGDQLHAES 780
            VNEKRFPTWRKFLQTFLSQGGVIEAFPPADNVTNLTVDMLIEPNGKISVLSTGDQLHAES
Sbjct: 721  VNEKRFPTWRKFLQTFLSQGGVIEAFPPADNVTNLTVDMLIEPNGKISVLSTGDQLHAES 780

Query: 781  PFISSGTTVPQTSVDPQVLTYLCLQIGKACRMRDVVGYFSIDLVTFIDPSTLEQQVWATG 840
            PFISSGTTVPQTSVDPQVLTYLCLQIGKACRMRDVVGYFSIDLVTFIDPSTLEQQVWATG
Sbjct: 781  PFISSGTTVPQTSVDPQVLTYLCLQIGKACRMRDVVGYFSIDLVTFIDPSTLEQQVWATG 840

Query: 841  LNLAYSDQLALTQLTLYLTNGHLDCSLSTLEVPRFVPKERKKTKCMSALSMPMLATSRYA 900
            LNLAYSDQLALTQLTLYLTNGHLDCSLSTLEVPRFVPKERKKTKCMSALSMPMLATSRYA
Sbjct: 841  LNLAYSDQLALTQLTLYLTNGHLDCSLSTLEVPRFVPKERKKTKCMSALSMPMLATSRYA 900

Query: 901  VMTTQLRHSNLSLVFHYVFLQICRAHGIGYDLEERQGTVFILYEHLKRHKLGMLTIGEDL 960
            VMTTQLRHSNLSLVFHYVFLQICRAHGIGYDLEERQGTVFILYEHLKRHKLGMLTIGEDL
Sbjct: 901  VMTTQLRHSNLSLVFHYVFLQICRAHGIGYDLEERQGTVFILYEHLKRHKLGMLTIGEDL 960

Query: 961  QGVLMTFARHLFIIHQEISAPNMQGETNFKTTIADIETILRVTKENKMRFEEEQQSKDDK 1020
            QGVLMTFARHLFIIHQEISAPNMQGETNFKTTIADIETILRVTKENKMRFEEEQQSKDDK
Sbjct: 961  QGVLMTFARHLFIIHQEISAPNMQGETNFKTTIADIETILRVTKENKMRFEEEQQSKDDK 1020

Query: 1021 NLSKPKK 1027
            NLSKPKK
Sbjct: 1021 NLSKPKK 1027


>gi|12232475 IQ motif containing H isoform 2 [Homo sapiens]
          Length = 621

 Score =  606 bits (1562), Expect = e-173
 Identities = 298/301 (99%), Positives = 299/301 (99%)

Query: 636 MIEQLSQLITDHLQIQRWLFKMDSEFRGNGTAFCDIPSYLKCYKWVLKESSRYGLEDWRK 695
           MIEQLSQLITDHLQIQRWLFKMDSEFRGNGTAFCDIPSYLKCYKWVLKESSRYGLEDWRK
Sbjct: 297 MIEQLSQLITDHLQIQRWLFKMDSEFRGNGTAFCDIPSYLKCYKWVLKESSRYGLEDWRK 356

Query: 696 KWAQEPALVKISEELAGILAQHAQPVNEKRFPTWRKFLQTFLSQGGVIEAFPPADNVTNL 755
           KWAQEPALVKISEELAGILAQHAQPVNEKRFPTWRKFLQTFLSQGGVIEAFPPADNVTNL
Sbjct: 357 KWAQEPALVKISEELAGILAQHAQPVNEKRFPTWRKFLQTFLSQGGVIEAFPPADNVTNL 416

Query: 756 TVDMLIEPNGKISVLSTGDQLHAESPFISSGTTVPQTSVDPQVLTYLCLQIGKACRMRDV 815
           TVDMLIEPNGKISVLSTGDQLHAESPFISSGTTVPQTSVDPQVLTYLCLQIGKACRMRDV
Sbjct: 417 TVDMLIEPNGKISVLSTGDQLHAESPFISSGTTVPQTSVDPQVLTYLCLQIGKACRMRDV 476

Query: 816 VGYFSIDLVTFIDPSTLEQQVWATGLNLAYSDQLALTQLTLYLTNGHLDCSLSTLEVPRF 875
           VGYFSIDLVTFIDPSTLEQQVWATGLNLAYSDQLALTQLTLYLTNGHLDCSLSTLEVPRF
Sbjct: 477 VGYFSIDLVTFIDPSTLEQQVWATGLNLAYSDQLALTQLTLYLTNGHLDCSLSTLEVPRF 536

Query: 876 VPKERKKTKCMSALSMPMLATSRYAVMTTQLRHSNLSLVFHYVFLQICRAHGIGYDLEER 935
           VPKERKKTKCMSALSMPMLATSRYAVMTTQLRHSNLSLVFHYVFLQICRAHGIGYDLE  
Sbjct: 537 VPKERKKTKCMSALSMPMLATSRYAVMTTQLRHSNLSLVFHYVFLQICRAHGIGYDLENN 596

Query: 936 Q 936
           +
Sbjct: 597 R 597



 Score =  600 bits (1546), Expect = e-171
 Identities = 294/294 (100%), Positives = 294/294 (100%)

Query: 251 KAMKVKTPLRALKSLWDYDFLIYDGVIDNTAPDFLAFKEHFSLAWGGIFSLLEHVEKFLR 310
           KAMKVKTPLRALKSLWDYDFLIYDGVIDNTAPDFLAFKEHFSLAWGGIFSLLEHVEKFLR
Sbjct: 3   KAMKVKTPLRALKSLWDYDFLIYDGVIDNTAPDFLAFKEHFSLAWGGIFSLLEHVEKFLR 62

Query: 311 NYAIPEVKIKGNNLVALLPEFELTNKLTRYDLLSVLEDPAHVQMLINLPGQRYKGQDGNS 370
           NYAIPEVKIKGNNLVALLPEFELTNKLTRYDLLSVLEDPAHVQMLINLPGQRYKGQDGNS
Sbjct: 63  NYAIPEVKIKGNNLVALLPEFELTNKLTRYDLLSVLEDPAHVQMLINLPGQRYKGQDGNS 122

Query: 371 EAAMKIQATWKCYKARKFFLFYRQQKWASGVIAIAWLLYCHKTRLKKILKESRQRHLENF 430
           EAAMKIQATWKCYKARKFFLFYRQQKWASGVIAIAWLLYCHKTRLKKILKESRQRHLENF
Sbjct: 123 EAAMKIQATWKCYKARKFFLFYRQQKWASGVIAIAWLLYCHKTRLKKILKESRQRHLENF 182

Query: 431 RIRAKHLAANWNRIRTSRRTIIHIPSLGYSQPVREHIADFNTQQNMQLGRLCDILDANVN 490
           RIRAKHLAANWNRIRTSRRTIIHIPSLGYSQPVREHIADFNTQQNMQLGRLCDILDANVN
Sbjct: 183 RIRAKHLAANWNRIRTSRRTIIHIPSLGYSQPVREHIADFNTQQNMQLGRLCDILDANVN 242

Query: 491 VIYICSHHMNDELVLYYKKILSLHAAVKSGNLEDRSDLQDRFKIITPEAVNIFP 544
           VIYICSHHMNDELVLYYKKILSLHAAVKSGNLEDRSDLQDRFKIITPEAVNIFP
Sbjct: 243 VIYICSHHMNDELVLYYKKILSLHAAVKSGNLEDRSDLQDRFKIITPEAVNIFP 296


>gi|58331148 matrix metalloproteinase 11 preproprotein [Homo
           sapiens]
          Length = 488

 Score = 34.7 bits (78), Expect = 0.47
 Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 2/56 (3%)

Query: 173 SMIERGLIPPTARITFQNPPITPRAAP--LHSFDEARKIPTVATFTIPREPPPSPA 226
           S   R L+PP   +  Q PP+  RA P   H     R+ P      +P  P P+PA
Sbjct: 9   SAAARALLPPMLLLLLQPPPLLARALPPDAHHLHAERRGPQPWHAALPSSPAPAPA 64


>gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens]
          Length = 1597

 Score = 34.3 bits (77), Expect = 0.62
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 12/78 (15%)

Query: 180 IPPTARITFQNPPITPRAAPLHSFDEARKIPTVATFTIPREPPPSPAEVKFFPKKQRSKG 239
           +PPT  +    P + P +AP  S    R +P +     P EPPP P          +S+G
Sbjct: 813 LPPTPDLP--QPHLPPISAP-GSSRIYRPLPPLPIIDPPTEPPPLPP---------KSRG 860

Query: 240 KSRRSRGHHDRKAMKVKT 257
           +SR +RG H       KT
Sbjct: 861 RSRSTRGGHMNSGGHAKT 878


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 33.5 bits (75), Expect = 1.1
 Identities = 28/80 (35%), Positives = 36/80 (45%), Gaps = 7/80 (8%)

Query: 155 PYFTPIPVLQADAHKGILSMIERGLIPPTARITFQNPPI--TPRAAPLHSFDEARK-IPT 211
           PY  P   + A A    L M +  L  P A++  Q PPI   P   PL   D     +P 
Sbjct: 761 PYLAPASQVGAPAQLKPLQMPQAPL-QPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPD 819

Query: 212 VATFTIPREPPP---SPAEV 228
           + T T+P  PPP   SPA +
Sbjct: 820 LPTATVPPVPPPQYFSPAVI 839


>gi|110431348 deleted in colorectal carcinoma [Homo sapiens]
          Length = 1447

 Score = 32.3 bits (72), Expect = 2.4
 Identities = 57/243 (23%), Positives = 89/243 (36%), Gaps = 55/243 (22%)

Query: 24   QLKEKLTKFSPEEKGETLDIQSLETAIKRTEVGLRIHIEKYLNVVNQNVLTTSVNDESLY 83
            Q K++ T  + + KG   D++  +  I   E+ ++       N+   +    +  D  + 
Sbjct: 1129 QRKKRATHSAGKRKGSQKDLRPPDLWIHHEEMEMK-------NIEKPSGTDPAGRDSPI- 1180

Query: 84   TPQASKWLLPTVIDQKSFIFPQESEGTFWQPQRQHSSSLPVF---------PRAKIKVSK 134
              Q+ + L P    Q       +S     Q   +  SS+            PRAK+ +  
Sbjct: 1181 --QSCQDLTPVSHSQSETQLGSKSTSHSGQDTEEAGSSMSTLERSLAARRAPRAKLMIPM 1238

Query: 135  LIKGSN---ISSLTV-----------LPSSHCTDPY--FT----PIPVLQADAHKGILSM 174
              + +N   +S++ V           LPS  C  P+  FT    P P L  D   G    
Sbjct: 1239 DAQSNNPAVVSAIPVPTLESAQYPGILPSPTCGYPHPQFTLRPVPFPTLSVDRGFGAGRS 1298

Query: 175  IERGLIPPTARITFQNPPITPRAAPLHSFDE---ARKIPT--------VATFTIPREPPP 223
                  P T     Q PP+ P + P HS  E   +R IPT        + +F  P  PPP
Sbjct: 1299 QSVSEGPTT-----QQPPMLPPSQPEHSSSEEAPSRTIPTACVRPTHPLRSFANPLLPPP 1353

Query: 224  SPA 226
              A
Sbjct: 1354 MSA 1356


>gi|239745414 PREDICTED: NPIP-like protein 2 isoform 2 [Homo
           sapiens]
          Length = 380

 Score = 32.3 bits (72), Expect = 2.4
 Identities = 38/138 (27%), Positives = 53/138 (38%), Gaps = 24/138 (17%)

Query: 115 QRQHSSSLPVFPRAKIKVSKLIKG------SNISSLTVLPSSHCTDP--YFTPIPVLQAD 166
           + +HSS LP +P    +  K   G      +   S+T    S  T P    TP+P    D
Sbjct: 219 EHRHSSGLPYWPYLTAETLKNRMGHQPPPPTQQHSITDNSLSLKTPPECLLTPLPPSADD 278

Query: 167 AHKGILSMIERGLIPPTARITFQNPPITPRAAPLHSFDEARKIPTVATFTIPREPPPSPA 226
             K           PP   +T    P+ P A P  S D+  K P +AT     E PP P 
Sbjct: 279 NLK----------TPPECLLT----PLPPSAPP--SADDNLKTPPLATQEAEAEKPPKPK 322

Query: 227 EVKFFPKKQRSKGKSRRS 244
             +    +   + K RR+
Sbjct: 323 RWRAAEMESPPEPKRRRA 340


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
            sapiens]
          Length = 3969

 Score = 31.2 bits (69), Expect = 5.2
 Identities = 45/172 (26%), Positives = 72/172 (41%), Gaps = 19/172 (11%)

Query: 73   LTTSVN-----DESLYTPQASKWLLPTVIDQKSFIFPQESEGTFWQPQRQHSSSLPVF-- 125
            LTT +N      +SL+ P ASK LLP    Q    FP  ++ +F        S L +   
Sbjct: 3131 LTTGLNPSLPTSQSLF-PSASKGLLPMSHHQHLHSFPAATQSSFPPNISNPPSGLLIGVQ 3189

Query: 126  --PRAKIKVSKLIKGSNISSLTVLPSSHCTDPYFTPIPVLQADAHKGILSMIERGLIPPT 183
              P  ++ VS+  + +++S+    PSS        PI  LQ   +K +        I P+
Sbjct: 3190 PPPDPQLLVSESSQRTDLSTTVATPSSGLKK---RPISRLQTRKNKKLAPSSTPSNIAPS 3246

Query: 184  ---ARITFQNPPITPRAAPLH-SFDEARKIPTVATFTIPREPPPSPAEVKFF 231
               + +T  N   TP   P H S  +   + T +  T+P     S + + +F
Sbjct: 3247 DVVSNMTLIN--FTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYF 3296


>gi|46370073 GRB2-associated binding protein 1 isoform b [Homo
           sapiens]
          Length = 694

 Score = 31.2 bits (69), Expect = 5.2
 Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 4/47 (8%)

Query: 180 IPPTARITFQNPPITPRAAPLHSFDEARKIPTVATFTIPREPPPSPA 226
           IPPT   T+Q     PR  P  +  +  K+ T+     PR P P PA
Sbjct: 309 IPPTPGNTYQ----IPRTFPEGTLGQTSKLDTIPDIPPPRPPKPHPA 351


>gi|46370071 GRB2-associated binding protein 1 isoform a [Homo
           sapiens]
          Length = 724

 Score = 31.2 bits (69), Expect = 5.2
 Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 4/47 (8%)

Query: 180 IPPTARITFQNPPITPRAAPLHSFDEARKIPTVATFTIPREPPPSPA 226
           IPPT   T+Q     PR  P  +  +  K+ T+     PR P P PA
Sbjct: 309 IPPTPGNTYQ----IPRTFPEGTLGQTSKLDTIPDIPPPRPPKPHPA 351


>gi|239741653 PREDICTED: hypothetical protein XP_002342271 [Homo
           sapiens]
          Length = 636

 Score = 31.2 bits (69), Expect = 5.2
 Identities = 14/42 (33%), Positives = 21/42 (50%)

Query: 167 AHKGILSMIERGLIPPTARITFQNPPITPRAAPLHSFDEARK 208
           +H+G+L+   RG +PP     F  PP T   +P   F   R+
Sbjct: 225 SHRGLLTPRRRGFLPPPRHRGFLPPPATAAFSPPRLFTPCRR 266


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 30.8 bits (68), Expect = 6.8
 Identities = 32/92 (34%), Positives = 43/92 (46%), Gaps = 14/92 (15%)

Query: 137 KGSNISSLTVL--PSSHCTDPYFTPIPVLQADAHKGILSMIERGLIPPTARITFQNPPIT 194
           K  NISSL+ L  P+ H  D +    P+      +G+ S  ++ L PP A I    PP  
Sbjct: 608 KKLNISSLSQLSPPNDH-KDIHAALQPM------EGMASNQQKALPPPPASI----PPPP 656

Query: 195 PRAAPLHSFDEARKIPTV-ATFTIPREPPPSP 225
           P  + L S   A  +P V A   +P  PPP P
Sbjct: 657 PLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPP 688


>gi|126116596 asp (abnormal spindle)-like, microcephaly associated
            [Homo sapiens]
          Length = 3477

 Score = 30.8 bits (68), Expect = 6.8
 Identities = 15/46 (32%), Positives = 28/46 (60%)

Query: 372  AAMKIQATWKCYKARKFFLFYRQQKWASGVIAIAWLLYCHKTRLKK 417
            AA  IQ TW+ YK +     +++++ A+ +I +A + +  K RL+K
Sbjct: 1269 AARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRK 1314


>gi|4501893 actinin, alpha 2 [Homo sapiens]
          Length = 894

 Score = 30.8 bits (68), Expect = 6.8
 Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 11/98 (11%)

Query: 637 IEQLSQLITDHLQIQRWLFKMDSEFRGNGTAFCDIPSYLKCYKWVLKESSRYG---LEDW 693
           IE++  LIT H Q +  L + D E +       ++   ++ Y   +  S+ Y    +++ 
Sbjct: 548 IEEIQSLITAHEQFKATLPEADGERQSIMAIQNEVEKVIQSYNIRISSSNPYSTVTMDEL 607

Query: 694 RKKWAQEPALVKI-----SEELAGILAQHAQPVNEKRF 726
           R KW +   LV I      EELA    QHA     ++F
Sbjct: 608 RTKWDKVKQLVPIRDQSLQEELA---RQHANERLRRQF 642


>gi|124378039 SEC16 homolog A [Homo sapiens]
          Length = 2357

 Score = 30.4 bits (67), Expect = 8.9
 Identities = 22/56 (39%), Positives = 28/56 (50%), Gaps = 3/56 (5%)

Query: 178  GLIPPTARITFQNPPIT-PRAAPLHSFDEARKIPTVATFTIPREPPPSPAEVKFFP 232
            GL  P A +   NP +  P  +P HS    R +P+ A  T+P  P  SPA V  FP
Sbjct: 1919 GLSQPGA-LGIANPLLAVPAPSPEHSSPSVRLLPS-APQTLPDGPLASPARVPMFP 1972


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 30.4 bits (67), Expect = 8.9
 Identities = 47/209 (22%), Positives = 76/209 (36%), Gaps = 22/209 (10%)

Query: 73   LTTSVNDESLYTPQASKWLLPTVIDQKSFIFPQESEGTFWQPQRQHSSSLPVF--PRAKI 130
            L  S + +   TP+ +        D+ S   P+    T  + Q   S+  PV   P ++ 
Sbjct: 1455 LQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRT 1514

Query: 131  KVSKLIKGSNISSLTVLPS------SHCTDPYFTPIPVLQADAHKGILSMIERG------ 178
               +  + S  +  TV+P+      S  TD   TP P  +A   +   S ++        
Sbjct: 1515 TRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPI 1574

Query: 179  ---LIPPTARITFQNPPITPRAAPLHSFDEARKIPTVATFTIPREPPPSPAEVKFFPKKQ 235
               L P T+R     P  T RA    +   + K P     T P   P +  +    PK  
Sbjct: 1575 APELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKL- 1633

Query: 236  RSKGKSRRSRGHHDRKAMKVKTPLRALKS 264
                 SR +R   +R ++K   P+    S
Sbjct: 1634 ----TSRATRRKTNRSSVKTPKPVEPAAS 1658


>gi|148833513 RNA binding motif protein 47 isoform a [Homo sapiens]
          Length = 593

 Score = 30.4 bits (67), Expect = 8.9
 Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 5/64 (7%)

Query: 405 AWLLYCHKTRLKKILKESRQRHLENFRIRAKHLAANWNRIRTSRRTIIHIPSLGYSQPVR 464
           A+++YCHK   K+ ++E     L N+ IR   L      +   R  I  IP +   + + 
Sbjct: 114 AFVMYCHKHEAKRAVRE-----LNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEIL 168

Query: 465 EHIA 468
           E IA
Sbjct: 169 EEIA 172


>gi|148833511 RNA binding motif protein 47 isoform b [Homo sapiens]
          Length = 524

 Score = 30.4 bits (67), Expect = 8.9
 Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 5/64 (7%)

Query: 405 AWLLYCHKTRLKKILKESRQRHLENFRIRAKHLAANWNRIRTSRRTIIHIPSLGYSQPVR 464
           A+++YCHK   K+ ++E     L N+ IR   L      +   R  I  IP +   + + 
Sbjct: 114 AFVMYCHKHEAKRAVRE-----LNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEIL 168

Query: 465 EHIA 468
           E IA
Sbjct: 169 EEIA 172


>gi|209969832 FAST kinase domains 2 [Homo sapiens]
          Length = 710

 Score = 30.4 bits (67), Expect = 8.9
 Identities = 28/161 (17%), Positives = 72/161 (44%), Gaps = 8/161 (4%)

Query: 494 ICSHHMNDELVLYYKKIL-SLHAAVKSGNLEDRSDLQDRFKIITPEAVNIFPKHHMCLAT 552
           +C H M +  ++ YK +L SLHA VK G +   + L      +T E +N   +  + + +
Sbjct: 216 LCEHMMREAKIMQYKYLLFSLHAIVKLG-IPQNTILVQTLLRVTQERINECDEICLSVLS 274

Query: 553 HLMYSPKAIKRIKNLIRGTEAYIVSGLLHRDDLAVADMLDIPILGSEPELAHLYSTKSGG 612
            ++ + +  K +  L  G    +   +   +D+    ++ +  +G +  +A     +   
Sbjct: 275 TVLEAMEPCKNVHVLRTGFRILVDQQVWKIEDVFTLQVV-MKCIGKDAPIALKRKLEMKA 333

Query: 613 KRVFDSANVAVPPGIYDIYSQQQ-----MIEQLSQLITDHL 648
            R  D  +V     ++++ +        ++++ S+++ D++
Sbjct: 334 LRELDRFSVLNSQHMFEVLAAMNHRSLILLDECSKVVLDNI 374


>gi|209969830 FAST kinase domains 2 [Homo sapiens]
          Length = 710

 Score = 30.4 bits (67), Expect = 8.9
 Identities = 28/161 (17%), Positives = 72/161 (44%), Gaps = 8/161 (4%)

Query: 494 ICSHHMNDELVLYYKKIL-SLHAAVKSGNLEDRSDLQDRFKIITPEAVNIFPKHHMCLAT 552
           +C H M +  ++ YK +L SLHA VK G +   + L      +T E +N   +  + + +
Sbjct: 216 LCEHMMREAKIMQYKYLLFSLHAIVKLG-IPQNTILVQTLLRVTQERINECDEICLSVLS 274

Query: 553 HLMYSPKAIKRIKNLIRGTEAYIVSGLLHRDDLAVADMLDIPILGSEPELAHLYSTKSGG 612
            ++ + +  K +  L  G    +   +   +D+    ++ +  +G +  +A     +   
Sbjct: 275 TVLEAMEPCKNVHVLRTGFRILVDQQVWKIEDVFTLQVV-MKCIGKDAPIALKRKLEMKA 333

Query: 613 KRVFDSANVAVPPGIYDIYSQQQ-----MIEQLSQLITDHL 648
            R  D  +V     ++++ +        ++++ S+++ D++
Sbjct: 334 LRELDRFSVLNSQHMFEVLAAMNHRSLILLDECSKVVLDNI 374


>gi|45267832 FAST kinase domains 2 [Homo sapiens]
          Length = 710

 Score = 30.4 bits (67), Expect = 8.9
 Identities = 28/161 (17%), Positives = 72/161 (44%), Gaps = 8/161 (4%)

Query: 494 ICSHHMNDELVLYYKKIL-SLHAAVKSGNLEDRSDLQDRFKIITPEAVNIFPKHHMCLAT 552
           +C H M +  ++ YK +L SLHA VK G +   + L      +T E +N   +  + + +
Sbjct: 216 LCEHMMREAKIMQYKYLLFSLHAIVKLG-IPQNTILVQTLLRVTQERINECDEICLSVLS 274

Query: 553 HLMYSPKAIKRIKNLIRGTEAYIVSGLLHRDDLAVADMLDIPILGSEPELAHLYSTKSGG 612
            ++ + +  K +  L  G    +   +   +D+    ++ +  +G +  +A     +   
Sbjct: 275 TVLEAMEPCKNVHVLRTGFRILVDQQVWKIEDVFTLQVV-MKCIGKDAPIALKRKLEMKA 333

Query: 613 KRVFDSANVAVPPGIYDIYSQQQ-----MIEQLSQLITDHL 648
            R  D  +V     ++++ +        ++++ S+++ D++
Sbjct: 334 LRELDRFSVLNSQHMFEVLAAMNHRSLILLDECSKVVLDNI 374


>gi|157384986 transducin-like enhancer protein 3 isoform b [Homo
           sapiens]
          Length = 769

 Score = 30.4 bits (67), Expect = 8.9
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 19/75 (25%)

Query: 192 PITPRAAPLHS-----FDEARKIPTVATFTIPREPPPSPAEVKFFPKKQRSKGKSRRSRG 246
           P TPR +P HS      D+AR        ++ ++ P SPA V        SK K     G
Sbjct: 257 PATPRVSPAHSPPENGLDKAR--------SLKKDAPTSPASVASSSSTPSSKTK---DLG 305

Query: 247 HHDRKA---MKVKTP 258
           H+D+ +   +K  TP
Sbjct: 306 HNDKSSTPGLKSNTP 320


>gi|157384984 transducin-like enhancer protein 3 isoform c [Homo
           sapiens]
          Length = 760

 Score = 30.4 bits (67), Expect = 8.9
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 19/75 (25%)

Query: 192 PITPRAAPLHS-----FDEARKIPTVATFTIPREPPPSPAEVKFFPKKQRSKGKSRRSRG 246
           P TPR +P HS      D+AR        ++ ++ P SPA V        SK K     G
Sbjct: 257 PATPRVSPAHSPPENGLDKAR--------SLKKDAPTSPASVASSSSTPSSKTK---DLG 305

Query: 247 HHDRKA---MKVKTP 258
           H+D+ +   +K  TP
Sbjct: 306 HNDKSSTPGLKSNTP 320


>gi|157384982 transducin-like enhancer protein 3 isoform a [Homo
           sapiens]
          Length = 772

 Score = 30.4 bits (67), Expect = 8.9
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 19/75 (25%)

Query: 192 PITPRAAPLHS-----FDEARKIPTVATFTIPREPPPSPAEVKFFPKKQRSKGKSRRSRG 246
           P TPR +P HS      D+AR        ++ ++ P SPA V        SK K     G
Sbjct: 257 PATPRVSPAHSPPENGLDKAR--------SLKKDAPTSPASVASSSSTPSSKTK---DLG 305

Query: 247 HHDRKA---MKVKTP 258
           H+D+ +   +K  TP
Sbjct: 306 HNDKSSTPGLKSNTP 320


>gi|31377705 centrosomal protein 97kDa [Homo sapiens]
          Length = 865

 Score = 30.4 bits (67), Expect = 8.9
 Identities = 15/77 (19%), Positives = 40/77 (51%), Gaps = 1/77 (1%)

Query: 370 SEAAMKIQATWKCYKARKFFLFYRQQKWASGVIAIAWLLYCHKTRLKKILKESRQRHLEN 429
           ++AA K+QA W+ + AR +    +  ++   +  +   + C    ++++ KE  +  ++ 
Sbjct: 559 NDAATKLQACWRGFYARNYNPQAKDVRYEIRLRRMQEHIVCLTDEIRRLRKERDEERIKK 618

Query: 430 FRIRAKHLAANWNRIRT 446
           F ++ +     WN++R+
Sbjct: 619 F-VQEEAFRFLWNQVRS 634


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,311,756
Number of Sequences: 37866
Number of extensions: 1793908
Number of successful extensions: 5142
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 5115
Number of HSP's gapped (non-prelim): 47
length of query: 1027
length of database: 18,247,518
effective HSP length: 112
effective length of query: 915
effective length of database: 14,006,526
effective search space: 12815971290
effective search space used: 12815971290
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.