BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|71774197 ubiquitin specific protease 47 [Homo sapiens] (1287 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|71774197 ubiquitin specific protease 47 [Homo sapiens] 2588 0.0 gi|150378533 ubiquitin specific peptidase 7 [Homo sapiens] 184 6e-46 gi|41055953 ubiquitin thioesterase 40 [Homo sapiens] 160 1e-38 gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens] 153 1e-36 gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens] 153 1e-36 gi|149192845 ubiquitin specific protease 24 [Homo sapiens] 146 1e-34 gi|32313610 ubiquitin specific protease 18 [Homo sapiens] 144 4e-34 gi|239757637 PREDICTED: ubiquitin specific peptidase 41 [Homo sa... 140 6e-33 gi|239746654 PREDICTED: ubiquitin specific protease 41 [Homo sap... 139 1e-32 gi|74319833 ubiquitin specific protease 9, Y-linked [Homo sapiens] 138 4e-32 gi|110347427 ubiquitin specific protease 34 [Homo sapiens] 132 2e-30 gi|169215723 PREDICTED: ubiquitin specific peptidase 41 [Homo sa... 130 1e-29 gi|145309311 ubiquitin specific protease 9, X-linked isoform 4 [... 129 2e-29 gi|145309309 ubiquitin specific protease 9, X-linked isoform 3 [... 129 2e-29 gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens] 99 2e-20 gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens] 97 8e-20 gi|239742285 PREDICTED: hypothetical protein XP_002342486 [Homo ... 92 4e-18 gi|239742291 PREDICTED: hypothetical protein XP_002342477 [Homo ... 89 2e-17 gi|239742278 PREDICTED: hypothetical protein XP_002342472 [Homo ... 89 2e-17 gi|239742289 PREDICTED: hypothetical protein XP_002342476 [Homo ... 89 3e-17 gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sap... 86 2e-16 gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapi... 86 2e-16 gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens] 85 4e-16 gi|153792150 deubiquitinating enzyme 3 [Homo sapiens] 85 5e-16 gi|169172880 PREDICTED: Inactive ubiquitin carboxyl-terminal hyd... 84 1e-15 gi|169172882 PREDICTED: Ubiquitin carboxyl-terminal hydrolase 17... 83 1e-15 gi|169217654 PREDICTED: similar to deubiquitinating enzyme DUB1 ... 82 3e-15 gi|239758075 PREDICTED: similar to deubiquitinating enzyme DUB1 ... 82 4e-15 gi|239742297 PREDICTED: hypothetical protein XP_002342480 [Homo ... 82 4e-15 gi|239742287 PREDICTED: hypothetical protein XP_002342475 [Homo ... 82 4e-15 >gi|71774197 ubiquitin specific protease 47 [Homo sapiens] Length = 1287 Score = 2588 bits (6709), Expect = 0.0 Identities = 1287/1287 (100%), Positives = 1287/1287 (100%) Query: 1 MVPGEENQLVPKEAPLDHTSDKSLLDANFEPGKKNFLHLTDKDGEQPQILLEDSSAGEDS 60 MVPGEENQLVPKEAPLDHTSDKSLLDANFEPGKKNFLHLTDKDGEQPQILLEDSSAGEDS Sbjct: 1 MVPGEENQLVPKEAPLDHTSDKSLLDANFEPGKKNFLHLTDKDGEQPQILLEDSSAGEDS 60 Query: 61 VHDRFIGPLPREGSGGSTSDYVSQSYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFM 120 VHDRFIGPLPREGSGGSTSDYVSQSYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFM Sbjct: 61 VHDRFIGPLPREGSGGSTSDYVSQSYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFM 120 Query: 121 TPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEAW 180 TPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEAW Sbjct: 121 TPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEAW 180 Query: 181 QQHDVQELCRVMFDALEQKWKQTEQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIP 240 QQHDVQELCRVMFDALEQKWKQTEQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIP Sbjct: 181 QQHDVQELCRVMFDALEQKWKQTEQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIP 240 Query: 241 LVIRPYGSSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTL 300 LVIRPYGSSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTL Sbjct: 241 LVIRPYGSSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTL 300 Query: 301 QLKRFDFDYTTMHRIKLNDRMTFPEELDMSTFIDVEDEKSPQTESCTDSGAENEGSCHSD 360 QLKRFDFDYTTMHRIKLNDRMTFPEELDMSTFIDVEDEKSPQTESCTDSGAENEGSCHSD Sbjct: 301 QLKRFDFDYTTMHRIKLNDRMTFPEELDMSTFIDVEDEKSPQTESCTDSGAENEGSCHSD 360 Query: 361 QMSNDFSNDDGVDEGICLETNSGTEKISKSGLEKNSLIYELFSVMVHSGSAAGGHYYACI 420 QMSNDFSNDDGVDEGICLETNSGTEKISKSGLEKNSLIYELFSVMVHSGSAAGGHYYACI Sbjct: 361 QMSNDFSNDDGVDEGICLETNSGTEKISKSGLEKNSLIYELFSVMVHSGSAAGGHYYACI 420 Query: 421 KSFSDEQWYSFNDQHVSRITQEDIKKTHGGSSGSRGYYSSAFASSTNAYMLIYRLKDPAR 480 KSFSDEQWYSFNDQHVSRITQEDIKKTHGGSSGSRGYYSSAFASSTNAYMLIYRLKDPAR Sbjct: 421 KSFSDEQWYSFNDQHVSRITQEDIKKTHGGSSGSRGYYSSAFASSTNAYMLIYRLKDPAR 480 Query: 481 NAKFLEVDEYPEHIKNLVQKERELEEQEKRQREIERNTCKIKLFCLHPTKQVMMENKLEV 540 NAKFLEVDEYPEHIKNLVQKERELEEQEKRQREIERNTCKIKLFCLHPTKQVMMENKLEV Sbjct: 481 NAKFLEVDEYPEHIKNLVQKERELEEQEKRQREIERNTCKIKLFCLHPTKQVMMENKLEV 540 Query: 541 HKDKTLKEAVEMAYKMMDLEEVIPLDCCRLVKYDEFHDYLERSYEGEEDTPMGLLLGGVK 600 HKDKTLKEAVEMAYKMMDLEEVIPLDCCRLVKYDEFHDYLERSYEGEEDTPMGLLLGGVK Sbjct: 541 HKDKTLKEAVEMAYKMMDLEEVIPLDCCRLVKYDEFHDYLERSYEGEEDTPMGLLLGGVK 600 Query: 601 STYMFDLLLETRKPDQVFQSYKPGEVMVKVHVVDLKAESVAAPITVRAYLNQTVTEFKQL 660 STYMFDLLLETRKPDQVFQSYKPGEVMVKVHVVDLKAESVAAPITVRAYLNQTVTEFKQL Sbjct: 601 STYMFDLLLETRKPDQVFQSYKPGEVMVKVHVVDLKAESVAAPITVRAYLNQTVTEFKQL 660 Query: 661 ISKAIHLPAETMRIVLERCYNDLRLLSVSSKTLKAEGFFRSNKVFVESSETLDYQMAFAD 720 ISKAIHLPAETMRIVLERCYNDLRLLSVSSKTLKAEGFFRSNKVFVESSETLDYQMAFAD Sbjct: 661 ISKAIHLPAETMRIVLERCYNDLRLLSVSSKTLKAEGFFRSNKVFVESSETLDYQMAFAD 720 Query: 721 SHLWKLLDRHANTIRLFVLLPEQSPVSYSKRTAYQKAGGDSGNVDDDCERVKGPVGSLKS 780 SHLWKLLDRHANTIRLFVLLPEQSPVSYSKRTAYQKAGGDSGNVDDDCERVKGPVGSLKS Sbjct: 721 SHLWKLLDRHANTIRLFVLLPEQSPVSYSKRTAYQKAGGDSGNVDDDCERVKGPVGSLKS 780 Query: 781 VEAILEESTEKLKSLSLQQQQDGDNGDSSKSTETSDFENIESPLNERDSSASVDNRELEQ 840 VEAILEESTEKLKSLSLQQQQDGDNGDSSKSTETSDFENIESPLNERDSSASVDNRELEQ Sbjct: 781 VEAILEESTEKLKSLSLQQQQDGDNGDSSKSTETSDFENIESPLNERDSSASVDNRELEQ 840 Query: 841 HIQTSDPENFQSEERSDSDVNNDRSTSSVDSDILSSSHSSDTLCNADNAQIPLANGLDSH 900 HIQTSDPENFQSEERSDSDVNNDRSTSSVDSDILSSSHSSDTLCNADNAQIPLANGLDSH Sbjct: 841 HIQTSDPENFQSEERSDSDVNNDRSTSSVDSDILSSSHSSDTLCNADNAQIPLANGLDSH 900 Query: 901 SITSSRRTKANEGKKETWDTAEEDSGTDSEYDESGKSRGEMQYMYFKAEPYAADEGSGEG 960 SITSSRRTKANEGKKETWDTAEEDSGTDSEYDESGKSRGEMQYMYFKAEPYAADEGSGEG Sbjct: 901 SITSSRRTKANEGKKETWDTAEEDSGTDSEYDESGKSRGEMQYMYFKAEPYAADEGSGEG 960 Query: 961 HKWLMVHVDKRITLAAFKQHLEPFVGVLSSHFKVFRVYASNQEFESVRLNETLSSFSDDN 1020 HKWLMVHVDKRITLAAFKQHLEPFVGVLSSHFKVFRVYASNQEFESVRLNETLSSFSDDN Sbjct: 961 HKWLMVHVDKRITLAAFKQHLEPFVGVLSSHFKVFRVYASNQEFESVRLNETLSSFSDDN 1020 Query: 1021 KITIRLGRALKKGEYRVKVYQLLVNEQEPCKFLLDAVFAKGMTVRQSKEELIPQLREQCG 1080 KITIRLGRALKKGEYRVKVYQLLVNEQEPCKFLLDAVFAKGMTVRQSKEELIPQLREQCG Sbjct: 1021 KITIRLGRALKKGEYRVKVYQLLVNEQEPCKFLLDAVFAKGMTVRQSKEELIPQLREQCG 1080 Query: 1081 LELSIDRFRLRKKTWKNPGTVFLDYHIYEEDINISSNWEVFLEVLDGVEKMKSMSQLAVL 1140 LELSIDRFRLRKKTWKNPGTVFLDYHIYEEDINISSNWEVFLEVLDGVEKMKSMSQLAVL Sbjct: 1081 LELSIDRFRLRKKTWKNPGTVFLDYHIYEEDINISSNWEVFLEVLDGVEKMKSMSQLAVL 1140 Query: 1141 SRRWKPSEMKLDPFQEVVLESSSVDELREKLSEISGIPLDDIEFAKGRGTFPCDISVLDI 1200 SRRWKPSEMKLDPFQEVVLESSSVDELREKLSEISGIPLDDIEFAKGRGTFPCDISVLDI Sbjct: 1141 SRRWKPSEMKLDPFQEVVLESSSVDELREKLSEISGIPLDDIEFAKGRGTFPCDISVLDI 1200 Query: 1201 HQDLDWNPKVSTLNVWPLYICDDGAVIFYRDKTEELMELTDEQRNELMKKESSRLQKTGH 1260 HQDLDWNPKVSTLNVWPLYICDDGAVIFYRDKTEELMELTDEQRNELMKKESSRLQKTGH Sbjct: 1201 HQDLDWNPKVSTLNVWPLYICDDGAVIFYRDKTEELMELTDEQRNELMKKESSRLQKTGH 1260 Query: 1261 RVTYSPRKEKALKIYLDGAPNKDLTQD 1287 RVTYSPRKEKALKIYLDGAPNKDLTQD Sbjct: 1261 RVTYSPRKEKALKIYLDGAPNKDLTQD 1287 >gi|150378533 ubiquitin specific peptidase 7 [Homo sapiens] Length = 1102 Score = 184 bits (466), Expect = 6e-46 Identities = 107/249 (42%), Positives = 146/249 (58%), Gaps = 10/249 (4%) Query: 93 NKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLF 152 +K TGYVGL NQ TCY+NSLLQTLF T + R A+Y E +D S+P LQR+F Sbjct: 207 SKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEG--DDSSKSVPLALQRVF 264 Query: 153 VLLQTSKKRAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALEQKWKQTEQADLINEL 212 LQ S K + T +T+SFGW++ +++ QHDVQELCRV+ D +E K K T I +L Sbjct: 265 YELQHSDK-PVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKL 323 Query: 213 YQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPN 272 ++GK+ Y++C E Y R + Y DI L I+ G F S + ++ E LDG N Sbjct: 324 FRGKMVSYIQCKEVDYRSDRREDYYDIQLSIK--GKKNIFESFVD----YVAVEQLDGDN 377 Query: 273 QYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTF 332 +Y + +A KG++FL P +L LQL RF +D T IK+NDR FPE+L + F Sbjct: 378 KYDAGEHGLQ-EAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEF 436 Query: 333 IDVEDEKSP 341 + D K P Sbjct: 437 LQKTDPKDP 445 Score = 70.5 bits (171), Expect = 1e-11 Identities = 49/168 (29%), Positives = 82/168 (48%), Gaps = 22/168 (13%) Query: 394 KNSLIYELFSVMVHSGSAAGGHYYACIKSFSDEQWYSFNDQHVSRITQED-IKKTHGGSS 452 K+ Y L +V+VHSG GGHY + D +W F+D VSR T+E+ I+ +GG Sbjct: 443 KDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHD 502 Query: 453 GSRGYYSSAFASSTNAYMLIYRLKDPARNAKFLEV------DEYPEHIKNLVQKERELEE 506 + TNAYML+Y R +K EV + P+ + +Q+E+ +E Sbjct: 503 D-----DLSVRHCTNAYMLVY-----IRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEA 552 Query: 507 QEKRQREIERNTCKIKL-----FCLHPTKQVMMENKLEVHKDKTLKEA 549 Q++++R+ ++++ FC H + E K++ K LK + Sbjct: 553 QKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNS 600 >gi|41055953 ubiquitin thioesterase 40 [Homo sapiens] Length = 1247 Score = 160 bits (404), Expect = 1e-38 Identities = 93/247 (37%), Positives = 131/247 (53%), Gaps = 15/247 (6%) Query: 97 TGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYK--------WEFEESEEDPVTSIPYQL 148 T G+ NQ TCYLNSLLQTL TPEFR AL+ +E ++ + V IP QL Sbjct: 50 TNLSGIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGLFEDKDKPDAKVRIIPLQL 109 Query: 149 QRLFVLLQTSKKRAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALEQKWKQTEQADL 208 QRLF L + A T D+T SFGW S+E +QHDVQEL R++F ALE T DL Sbjct: 110 QRLFAQLLLLDQEAASTADLTDSFGWTSNEEMRQHDVQELNRILFSALETSLVGTSGHDL 169 Query: 209 INELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEAL-HAFIQPEI 267 I LY G + + + C EC R + +LD+ + ++ + +E+AL + +++ E+ Sbjct: 170 IYRLYHGTIVNQIVCKECKNVSERQEDFLDLTVAVK------NVSGLEDALWNMYVEEEV 223 Query: 268 LDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEEL 327 D N Y C C + A K + P LT+ L RF+FD+ R K TFP + Sbjct: 224 FDCDNLYHCGTCDRLVKAAKSAKLRKLPPFLTVSLLRFNFDFVKCERYKETSCYTFPLRI 283 Query: 328 DMSTFID 334 ++ F + Sbjct: 284 NLKPFCE 290 Score = 30.8 bits (68), Expect = 8.7 Identities = 34/153 (22%), Positives = 57/153 (37%), Gaps = 27/153 (17%) Query: 422 SFSDEQWYSFNDQHVSRITQEDIKKTHGGSSGSRGYYSSAFASSTNAYMLIYRLKDPARN 481 S S W+ ND V I ++DI++ F +AYML YR R Sbjct: 454 SISCPHWFDINDSKVQPIREKDIEQ--------------QFQGKESAYMLFYRKSQLQRP 499 Query: 482 AKFLEVDEY--PEHIKNLVQKERELEEQEKRQREIERNTCKIKLF----------CLHP- 528 + Y P H+ N + + ++ + + NT ++ L LHP Sbjct: 500 PEARANPRYGVPCHLLNEMDAANIELQTKRAECDSANNTFELHLHLGPQYHFFNGALHPV 559 Query: 529 TKQVMMENKLEVHKDKTLKEAVEMAYKMMDLEE 561 Q L K KTL + + +++++ E Sbjct: 560 VSQTESVWDLTFDKRKTLGDLRQSIFQLLEFWE 592 >gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens] Length = 485 Score = 153 bits (386), Expect = 1e-36 Identities = 121/457 (26%), Positives = 197/457 (43%), Gaps = 101/457 (22%) Query: 94 KSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEF------------EESEEDPV 141 + + +VGL N TCY+N+ LQ F+ E R ALY EE + +P Sbjct: 83 RKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKDYEPQ 142 Query: 142 TSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALEQ--- 198 T I LQ LF LLQ S +R I+ + ++ G D+ QQ D QE ++ LE Sbjct: 143 T-ICEHLQYLFALLQNSNRRYIDPSGFVKALGLDTG---QQQDAQEFSKLFMSLLEDTLS 198 Query: 199 KWKQTEQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEA 258 K K + +++ + + G+ C +CG E + + ++ L I Q + + Sbjct: 199 KQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNI------QGHKQLTDC 252 Query: 259 LHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLN 318 + F++ E L+G N+YFCE C+ K +A + +R L P L LQL RF FD T H+ KLN Sbjct: 253 ISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLN 312 Query: 319 DRMTFPEELDMSTFIDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICL 378 + F E LDM ++ E++G + ++S Sbjct: 313 TYIGFSEILDMEPYV------------------EHKGGSYVYELS--------------- 339 Query: 379 ETNSGTEKISKSGLEKNSLIYELFSVMVHSG-SAAGGHYYACIKSFSDEQWYSFNDQHVS 437 +V++H G SA GHY A +K +WY FND+ + Sbjct: 340 ------------------------AVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIE 375 Query: 438 RI--------TQEDIKKTHGGSSGSRGYYSSAFASSTNAYMLIYRLKDPARNAKFLEVDE 489 ++ +ED+ + S + S NAYML+YRL+ + ++V Sbjct: 376 KMEGKKLQLGIEEDLAEP-SKSQTRKPKCGKGTHCSRNAYMLVYRLQTQEKPNTTVQV-- 432 Query: 490 YPEHIKNLVQKERE------LEEQEKRQREIERNTCK 520 P ++ LV ++ +E E R++ +++ K Sbjct: 433 -PAFLQELVDRDNSKFEEWCIEMAEMRKQSVDKGKAK 468 >gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens] Length = 1035 Score = 153 bits (386), Expect = 1e-36 Identities = 121/457 (26%), Positives = 197/457 (43%), Gaps = 101/457 (22%) Query: 94 KSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEF------------EESEEDPV 141 + + +VGL N TCY+N+ LQ F+ E R ALY EE + +P Sbjct: 83 RKKNSFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCPSTCSDYMLGDGIQEEKDYEPQ 142 Query: 142 TSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALEQ--- 198 T I LQ LF LLQ S +R I+ + ++ G D+ QQ D QE ++ LE Sbjct: 143 T-ICEHLQYLFALLQNSNRRYIDPSGFVKALGLDTG---QQQDAQEFSKLFMSLLEDTLS 198 Query: 199 KWKQTEQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEA 258 K K + +++ + + G+ C +CG E + + ++ L I Q + + Sbjct: 199 KQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNI------QGHKQLTDC 252 Query: 259 LHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLN 318 + F++ E L+G N+YFCE C+ K +A + +R L P L LQL RF FD T H+ KLN Sbjct: 253 ISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLN 312 Query: 319 DRMTFPEELDMSTFIDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICL 378 + F E LDM ++ E++G + ++S Sbjct: 313 TYIGFSEILDMEPYV------------------EHKGGSYVYELS--------------- 339 Query: 379 ETNSGTEKISKSGLEKNSLIYELFSVMVHSG-SAAGGHYYACIKSFSDEQWYSFNDQHVS 437 +V++H G SA GHY A +K +WY FND+ + Sbjct: 340 ------------------------AVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIE 375 Query: 438 RI--------TQEDIKKTHGGSSGSRGYYSSAFASSTNAYMLIYRLKDPARNAKFLEVDE 489 ++ +ED+ + S + S NAYML+YRL+ + ++V Sbjct: 376 KMEGKKLQLGIEEDLAEP-SKSQTRKPKCGKGTHCSRNAYMLVYRLQTQEKPNTTVQV-- 432 Query: 490 YPEHIKNLVQKERE------LEEQEKRQREIERNTCK 520 P ++ LV ++ +E E R++ +++ K Sbjct: 433 -PAFLQELVDRDNSKFEEWCIEMAEMRKQSVDKGKAK 468 >gi|149192845 ubiquitin specific protease 24 [Homo sapiens] Length = 2460 Score = 146 bits (369), Expect = 1e-34 Identities = 112/395 (28%), Positives = 177/395 (44%), Gaps = 49/395 (12%) Query: 93 NKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLF 152 ++S +G+VGL N TCY+N++ Q L+M P +L ++ ++P S+ YQ+Q LF Sbjct: 1522 SRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLS--VDDDTDNPDDSVFYQVQSLF 1579 Query: 153 VLLQTSKKRAIETTDVTRSFGWDSSEAW--QQHDVQELCRVMFDALEQKWKQTEQADLIN 210 L SK + + + F + E + +Q D E + D +++ K+ + + Sbjct: 1580 GHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGRDQIFK 1639 Query: 211 ELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDG 270 +QG D C +C + R + ++ + L + + S+E +L F++ E+L+G Sbjct: 1640 NTFQGIYSDQKICKDCPHRYEREEAFMALNLGVT------SCQSLEISLDQFVRGEVLEG 1693 Query: 271 PNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMS 330 N Y+CE+CK+K K P +L + L RF FD+ + IK ++++ FP L+M Sbjct: 1694 SNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNM- 1752 Query: 331 TFIDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKS 390 P T S G D S N VD+G G K Sbjct: 1753 ---------EPYTVS---------GMARQDSSSEVGENGRSVDQG------GGGSPRKKV 1788 Query: 391 GLEKNSLIYELFSVMVHSGSAAGGHYYACIK---SFSDEQWYSFNDQHVSRITQEDIK-- 445 L +N YEL V+VHSG A GHYY+ IK +WY FND + D Sbjct: 1789 ALTEN---YELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLE 1845 Query: 446 -KTHGGSSGSRGY-----YSSAFASSTNAYMLIYR 474 + GG + Y Y+ NAYML Y+ Sbjct: 1846 YECFGGEYRPKVYDQTNPYTDVRRRYWNAYMLFYQ 1880 >gi|32313610 ubiquitin specific protease 18 [Homo sapiens] Length = 372 Score = 144 bits (364), Expect = 4e-34 Identities = 96/376 (25%), Positives = 166/376 (44%), Gaps = 61/376 (16%) Query: 98 GYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQT 157 G VGL N TC LNSL+Q M +F L + ++ S+P+Q+ L +Q Sbjct: 53 GLVGLHNIGQTCCLNSLIQVFVMNVDFTRILKRITVPRGADEQRRSVPFQMLLLLEKMQD 112 Query: 158 SKKRAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALEQKWKQTEQADLINELYQGKL 217 S+++A+ ++ + + QHD +L +++ ++ + + + LY ++ Sbjct: 113 SRQKAVRPLELAYCLQKCNVPLFVQHDAAQLYLKLWNLIKDQITDVHLVERLQALYTIRV 172 Query: 218 KDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPNQYFCE 277 KD + C++C E R + L +PL + S+ ++E+ALH F QP L ++ FCE Sbjct: 173 KDSLICVDCAMESSRNSSMLTLPLSLFDV-DSKPLKTLEDALHCFFQPRELSSKSKCFCE 231 Query: 278 RCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTFIDVED 337 C KK ++ L+ H P LT+ L RF + K+ + FP+ LD S + ++ Sbjct: 232 NCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTR--KICHSLYFPQSLDFSQILPMKR 289 Query: 338 EKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSGLEKNSL 397 E SC +++ S Sbjct: 290 E-----------------SCDAEEQSGG-------------------------------- 300 Query: 398 IYELFSVMVHSGSAAGGHYYACIKSFSDEQWYSFNDQHVSRITQEDIKKTHGGSSGSRGY 457 YELF+V+ H G A GHY I++ D +W+ FND ++ ++ EDI+ T+G + Sbjct: 301 QYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPN----- 355 Query: 458 YSSAFASSTNAYMLIY 473 + AY+L+Y Sbjct: 356 ----YHWQETAYLLVY 367 >gi|239757637 PREDICTED: ubiquitin specific peptidase 41 [Homo sapiens] Length = 344 Score = 140 bits (354), Expect = 6e-33 Identities = 96/366 (26%), Positives = 160/366 (43%), Gaps = 52/366 (14%) Query: 84 QSYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTS 143 Q +S I G VGL N TC LNSL+Q M +F L + ++ S Sbjct: 5 QLFSVPKISWDYRHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQRRS 64 Query: 144 IPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALEQKWKQT 203 +P+Q+ L +Q S+++A+ ++ + + QHD +L +++ ++ + Sbjct: 65 VPFQMLLLLEKMQDSRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQIADV 124 Query: 204 EQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFI 263 + + LY ++KD + CL+C E R + L + L S+ ++E+ALH F Sbjct: 125 HLVERLQALYMIRVKDSLICLDCAMESSRNSSMLTLRLSFFDV-DSKPLKTLEDALHCFF 183 Query: 264 QPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTF 323 QP L ++ FCE C KK ++ L+ H P LT+ L RF + K+ + F Sbjct: 184 QPRELSSKSKCFCENCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTR--KICHSLYF 241 Query: 324 PEELDMSTFIDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSG 383 P+ LD S + ++ E SC +++ S Sbjct: 242 PQSLDFSQILPMKRE-----------------SCDAEEQSGG------------------ 266 Query: 384 TEKISKSGLEKNSLIYELFSVMVHSGSAAGGHYYACIKSFSDEQWYSFNDQHVSRITQED 443 YELF+V+ H G A GHY I+S D +W+ FND ++ ++ ED Sbjct: 267 --------------QYELFAVIAHVGMADSGHYCVYIRSAVDGKWFCFNDSNICLVSWED 312 Query: 444 IKKTHG 449 I+ T+G Sbjct: 313 IQCTYG 318 >gi|239746654 PREDICTED: ubiquitin specific protease 41 [Homo sapiens] Length = 347 Score = 139 bits (351), Expect = 1e-32 Identities = 92/352 (26%), Positives = 156/352 (44%), Gaps = 52/352 (14%) Query: 98 GYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQT 157 G VGL N TC LNSL+Q M +F L + ++ S+P+Q+ L +Q Sbjct: 42 GLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQRRSVPFQMLLLLEKMQD 101 Query: 158 SKKRAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALEQKWKQTEQADLINELYQGKL 217 S+++A+ ++ + + QHD +L +++ ++ + + + LY ++ Sbjct: 102 SRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQIADVHLVERLQALYMIRM 161 Query: 218 KDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPNQYFCE 277 KD + CL+C E R + L + L S+ ++E+ALH F QP L ++ FCE Sbjct: 162 KDSLICLDCAMESSRNSSMLTLRLSFFDV-DSKPLKTLEDALHCFFQPRELSSKSKCFCE 220 Query: 278 RCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTFIDVED 337 C KK ++ L+ H P LT+ L RF + K+ + FP+ LD S + ++ Sbjct: 221 NCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTR--KICHSLYFPQSLDFSQILPMKR 278 Query: 338 EKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSGLEKNSL 397 E SC +++ S Sbjct: 279 E-----------------SCDAEEQSGG-------------------------------- 289 Query: 398 IYELFSVMVHSGSAAGGHYYACIKSFSDEQWYSFNDQHVSRITQEDIKKTHG 449 YELF+V+ H G A GHY I++ D +W+ FND ++ ++ EDI+ T+G Sbjct: 290 QYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYG 341 >gi|74319833 ubiquitin specific protease 9, Y-linked [Homo sapiens] Length = 2555 Score = 138 bits (347), Expect = 4e-32 Identities = 136/532 (25%), Positives = 208/532 (39%), Gaps = 114/532 (21%) Query: 98 GYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEF----------------EESEEDP- 140 G+VGL N TCY+NS++Q L+M P RN++ E ES DP Sbjct: 1557 GFVGLKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVDPR 1616 Query: 141 --VTSIPYQLQRLFVLLQTSKKRAIETTD-------------------VTRSFGWDSSEA 179 V P+Q + L +T ++ V R F W Sbjct: 1617 DDVFGYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGF-WKQFRL 1675 Query: 180 W-------QQHDVQELCRVMFDALEQKWKQTEQADLINELYQGKLKDYVRCLECGYEGWR 232 W +QHD E + D+L++ K +++++ G D C C + Sbjct: 1676 WGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKICQGCPHRYEC 1735 Query: 233 IDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFL 292 +++ + + IR + ++ ++L +I+ ++L+G N Y CE+C KK D K L Sbjct: 1736 EESFTTLNVDIRNH------QNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIK 1789 Query: 293 HFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTFIDVEDEKSPQTESCTDSGAE 352 P +L +QLKRFD+D+ IK ND FP ELDM + V + + ++ +E Sbjct: 1790 KLPRVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMGPY-TVAGVANLERDNV---NSE 1845 Query: 353 NEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSGLEKNSLIYELFSVMVHSGSAA 412 NE +Q N ET GT+ Y L V+VHSG A+ Sbjct: 1846 NELIEQKEQSDN--------------ETAGGTK-------------YRLVGVLVHSGQAS 1878 Query: 413 GGHYYACI-----KSFSDEQWYSFNDQHVSRITQEDIKKTHGGSSGSRGYYSSAFASST- 466 GGHYY+ I K + WY F+D V+ +D ++ G Y F Sbjct: 1879 GGHYYSYIIQRNGKDDQTDHWYKFDDGDVTECKMDDDEEMKNQCFGGE-YMGEVFDHMMK 1937 Query: 467 -----------NAYMLIYRLKDPARNAKFLEVDEYPEHIKNLVQKERELEEQEKRQREIE 515 NAY+L Y D +DE E I+ + + Q IE Sbjct: 1938 RMSYRRQKRWWNAYILFYEQMD--------MIDEDDEMIRYISELTIARPHQIIMSPAIE 1989 Query: 516 RNTCKIKLFCLHPTKQVMME-----NKLEVHKDKTLKEAVEMAYKMMDLEEV 562 R+ K + +H Q +E KL L A Y + + EE+ Sbjct: 1990 RSVRKQNVKFMHNRLQYSLEYFQFVKKLLTCNGVYLNPAPGQDYLLPEAEEI 2041 >gi|110347427 ubiquitin specific protease 34 [Homo sapiens] Length = 3546 Score = 132 bits (333), Expect = 2e-30 Identities = 101/401 (25%), Positives = 171/401 (42%), Gaps = 63/401 (15%) Query: 94 KSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFV 153 ++E +VGL N TCYL S +Q L+M PE R A++ ++ E + T + +LQ++F Sbjct: 1888 RAECRFVGLTNLGATCYLASTIQQLYMIPEARQAVFTAKYSEDMKHKTTLL--ELQKMFT 1945 Query: 154 LLQTSKKRAIETTDVTRSFGWDSS--EAWQQHDVQELCRVMFDALEQKWKQTEQADLINE 211 L S+ +A +++ D +Q D+ E + +E+ E + + Sbjct: 1946 YLMESECKAYNPRPFCKTYTMDKQPLNTGEQKDMTEFFTDLITKIEEM--SPELKNTVKS 2003 Query: 212 LYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGP 271 L+ G + + V L+C + + + + + ++ E+L + L+G Sbjct: 2004 LFGGVITNNVVSLDCEHVSQTAEEFYTVRCQVAD------MKNIYESLDEVTIKDTLEGD 2057 Query: 272 NQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMST 331 N Y C C KK A K F P +L+ R+ F+ TM + K+N +FP LDM Sbjct: 2058 NMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLDM-- 2115 Query: 332 FIDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSG 391 +P TE DF E G +++S Sbjct: 2116 --------TPYTE--------------------DFLMGKS-------ERKEGFKEVSDHS 2140 Query: 392 LEKNSLIYELFSVMVHSGSAAGGHYYACIK------SFSDEQWYSFNDQHVSRITQEDI- 444 + S Y+L V VH+G+A GGHYY+ I+ ++ + +WY FND V + Sbjct: 2141 KDSESYEYDLIGVTVHTGTADGGHYYSFIRDIVNPHAYKNNKWYLFNDAEVKPFDSAQLA 2200 Query: 445 KKTHGGSSGSRGYYS-------SAFASSTNAYMLIYRLKDP 478 + GG ++ Y S +F + +AYML Y+ +P Sbjct: 2201 SECFGGEMTTKTYDSVTDKFMDFSFEKTHSAYMLFYKRMEP 2241 >gi|169215723 PREDICTED: ubiquitin specific peptidase 41 [Homo sapiens] Length = 346 Score = 130 bits (326), Expect = 1e-29 Identities = 87/339 (25%), Positives = 147/339 (43%), Gaps = 52/339 (15%) Query: 98 GYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQT 157 G VGL N TC LNSL+Q M +F L + ++ S+P+Q+ L +Q Sbjct: 42 GLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQRRSVPFQMLLLLEKMQD 101 Query: 158 SKKRAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALEQKWKQTEQADLINELYQGKL 217 S+++A+ ++ + + QHD +L +++ ++ + + + LY ++ Sbjct: 102 SRQKAVWPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLIKDQIADVHLVERLQALYMIRM 161 Query: 218 KDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPNQYFCE 277 KD + CL+C E R + L + L S+ ++E+ALH F QP L ++ FCE Sbjct: 162 KDSLICLDCAMESSRNSSMLTLRLSFFDV-DSKPLKTLEDALHCFFQPRELSSKSKCFCE 220 Query: 278 RCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTFIDVED 337 C KK ++ L+ H P LT+ L RF + K+ + FP+ LD S + ++ Sbjct: 221 NCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTR--KICHSLYFPQSLDFSQILPMKR 278 Query: 338 EKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSGLEKNSL 397 E SC +++ S Sbjct: 279 E-----------------SCDAEEQSGG-------------------------------- 289 Query: 398 IYELFSVMVHSGSAAGGHYYACIKSFSDEQWYSFNDQHV 436 YELF+V+ H G A GHY I++ D +W+ FND ++ Sbjct: 290 QYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNI 328 >gi|145309311 ubiquitin specific protease 9, X-linked isoform 4 [Homo sapiens] Length = 2554 Score = 129 bits (324), Expect = 2e-29 Identities = 132/501 (26%), Positives = 196/501 (39%), Gaps = 110/501 (21%) Query: 98 GYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEF----------------EESEEDP- 140 G+VGL N TCY+NS++Q L+M P RN + E ES DP Sbjct: 1555 GFVGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVDPR 1614 Query: 141 --VTSIPYQLQRLFVLLQTSKKRAIETTD-------------------VTRSFGWDSSEA 179 V P Q + L +T ++ V R F W Sbjct: 1615 DDVFGYPQQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGF-WKQFRL 1673 Query: 180 W-------QQHDVQELCRVMFDALEQKWKQTEQADLINELYQGKLKDYVRCLECGYEGWR 232 W +QHD E + D+L++ K +++++ G D C C + Sbjct: 1674 WGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKICQGCPHRYEC 1733 Query: 233 IDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFL 292 +++ + + IR + ++ ++L +++ ++L+G N Y CE+C KK D K L Sbjct: 1734 EESFTTLNVDIRNH------QNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIK 1787 Query: 293 HFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTFIDVEDEKSPQTESCTDSG-A 351 P +L +QLKRFD+D+ IK ND FP ELDM E T +G A Sbjct: 1788 KLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDM--------------EPYTVAGVA 1833 Query: 352 ENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSGLEKNSLIYELFSVMVHSGSA 411 + EG D V+ L S + +G K Y L V+VHSG A Sbjct: 1834 KLEG--------------DNVNPESQLIQQSEQSESETAGSTK----YRLVGVLVHSGQA 1875 Query: 412 AGGHYYACI--KSFSD---EQWYSFNDQHVSRITQEDIKKTHGGSSGSRGYYSSAFASST 466 +GGHYY+ I ++ D +WY F+D V+ +D ++ G Y F Sbjct: 1876 SGGHYYSYIIQRNGGDGERNRWYKFDDGDVTECKMDDDEEMKNQCFGGE-YMGEVFDHMM 1934 Query: 467 ------------NAYMLIYRLKDPARNAKFLEVDEYPEHIKNLVQKERELEEQEKRQREI 514 NAY+L Y D + DE +I L R Q I Sbjct: 1935 KRMSYRRQKRWWNAYILFYERMDTID-----QDDELIRYISELAITTR--PHQIIMPSAI 1987 Query: 515 ERNTCKIKLFCLHPTKQVMME 535 ER+ K + +H Q ME Sbjct: 1988 ERSVRKQNVQFMHNRMQYSME 2008 >gi|145309309 ubiquitin specific protease 9, X-linked isoform 3 [Homo sapiens] Length = 2570 Score = 129 bits (324), Expect = 2e-29 Identities = 132/501 (26%), Positives = 196/501 (39%), Gaps = 110/501 (21%) Query: 98 GYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEF----------------EESEEDP- 140 G+VGL N TCY+NS++Q L+M P RN + E ES DP Sbjct: 1555 GFVGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVDPR 1614 Query: 141 --VTSIPYQLQRLFVLLQTSKKRAIETTD-------------------VTRSFGWDSSEA 179 V P Q + L +T ++ V R F W Sbjct: 1615 DDVFGYPQQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGF-WKQFRL 1673 Query: 180 W-------QQHDVQELCRVMFDALEQKWKQTEQADLINELYQGKLKDYVRCLECGYEGWR 232 W +QHD E + D+L++ K +++++ G D C C + Sbjct: 1674 WGEPVNLREQHDALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKICQGCPHRYEC 1733 Query: 233 IDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFL 292 +++ + + IR + ++ ++L +++ ++L+G N Y CE+C KK D K L Sbjct: 1734 EESFTTLNVDIRNH------QNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKRLLIK 1787 Query: 293 HFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTFIDVEDEKSPQTESCTDSG-A 351 P +L +QLKRFD+D+ IK ND FP ELDM E T +G A Sbjct: 1788 KLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDM--------------EPYTVAGVA 1833 Query: 352 ENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSGLEKNSLIYELFSVMVHSGSA 411 + EG D V+ L S + +G K Y L V+VHSG A Sbjct: 1834 KLEG--------------DNVNPESQLIQQSEQSESETAGSTK----YRLVGVLVHSGQA 1875 Query: 412 AGGHYYACI--KSFSD---EQWYSFNDQHVSRITQEDIKKTHGGSSGSRGYYSSAFASST 466 +GGHYY+ I ++ D +WY F+D V+ +D ++ G Y F Sbjct: 1876 SGGHYYSYIIQRNGGDGERNRWYKFDDGDVTECKMDDDEEMKNQCFGGE-YMGEVFDHMM 1934 Query: 467 ------------NAYMLIYRLKDPARNAKFLEVDEYPEHIKNLVQKERELEEQEKRQREI 514 NAY+L Y D + DE +I L R Q I Sbjct: 1935 KRMSYRRQKRWWNAYILFYERMDTID-----QDDELIRYISELAITTR--PHQIIMPSAI 1987 Query: 515 ERNTCKIKLFCLHPTKQVMME 535 ER+ K + +H Q ME Sbjct: 1988 ERSVRKQNVQFMHNRMQYSME 2008 >gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens] Length = 1123 Score = 99.4 bits (246), Expect = 2e-20 Identities = 91/347 (26%), Positives = 138/347 (39%), Gaps = 78/347 (22%) Query: 101 GLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKK 160 GL N TC+LN+ +Q L TP N L E S + +Q V + Sbjct: 123 GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHARSCHQGSFCMLCVMQNHIVQAFANSG 182 Query: 161 RAIETTDVTRSFGWDSSEA--WQQHDVQELCRVMFDALEQKW--------KQTEQADLIN 210 AI+ R + Q D E R DA+++ +QT+ L++ Sbjct: 183 NAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYTIDAMQKACLNGCAKLDRQTQATTLVH 242 Query: 211 ELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDG 270 +++ G L+ V+C C D YLD+ L IR QA A++ AL F++ ++L G Sbjct: 243 QIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIR-----QA-ANIVRALELFVKADVLSG 296 Query: 271 PNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMS 330 N Y C +CKKK A K +LTL LKRF K+ + +PE L++ Sbjct: 297 ENAYMCAKCKKKVPASKRFTIHRTSNVLTLSLKRF----ANFSGGKITKDVGYPEFLNIR 352 Query: 331 TFIDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKS 390 ++ ++N G Sbjct: 353 PYM-----------------SQNNG----------------------------------- 360 Query: 391 GLEKNSLIYELFSVMVHSG-SAAGGHYYACIKSFSDEQWYSFNDQHV 436 + ++Y L++V+VHSG S GHYY +K+ S+ QWY ND V Sbjct: 361 ----DPVMYGLYAVLVHSGYSCHAGHYYCYVKA-SNGQWYQMNDSLV 402 >gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens] Length = 370 Score = 97.4 bits (241), Expect = 8e-20 Identities = 97/407 (23%), Positives = 161/407 (39%), Gaps = 102/407 (25%) Query: 99 YVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTS 158 Y GLVN TCY NS+LQ L+ FR + ++ + +++ + + L LF + T Sbjct: 38 YFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKESLLTC---LADLFHSIATQ 94 Query: 159 KKRA--IETTDVTRSFGWDSS--EAWQQHDVQE----LCRVMFDALEQKWKQTEQ----- 205 KK+ I ++ + + Q D E L + D L+++ KQ +Q Sbjct: 95 KKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLP 154 Query: 206 --------------ADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQA 251 ++E++QG L + RCL C + + +LD+ + + + Sbjct: 155 NGNIDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDV------EQ 208 Query: 252 FASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTT 311 S+ L F E L +Y+CE C+ K +A K ++ P +L L LKRF + Sbjct: 209 NTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQL 268 Query: 312 MHRIKLNDRMTFPEELDMSTFIDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDG 371 KL+ R+ FP EL + S D +N D Sbjct: 269 HRYTKLSYRVVFPLELRLF------------------------------NTSGDATNPD- 297 Query: 372 VDEGICLETNSGTEKISKSGLEKNSLIYELFSVMVHSGSAAG-GHYYACIKSFSDEQWYS 430 +Y+L +V+VH GS GHY A +K S + W Sbjct: 298 -------------------------RMYDLVAVVVHCGSGPNRGHYIAIVK--SHDFWLL 330 Query: 431 FNDQHVSRITQEDIKKTHGGSSGSRGYYSSAFASSTNAYMLIYRLKD 477 F+D V +I + I++ + G S +S + Y+L Y+ +D Sbjct: 331 FDDDIVEKIDAQAIEEFY-------GLTSDISKNSESGYILFYQSRD 370 >gi|239742285 PREDICTED: hypothetical protein XP_002342486 [Homo sapiens] Length = 559 Score = 91.7 bits (226), Expect = 4e-18 Identities = 112/450 (24%), Positives = 177/450 (39%), Gaps = 102/450 (22%) Query: 101 GLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKK 160 GL N TCY+N+ LQ L TP N + E ++ + +Q + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140 Query: 161 RAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDAL--------EQKWKQTEQADLINEL 212 I+ + + +Q D E DA+ +Q ++ LI+++ Sbjct: 141 HVIQPSQALAA----GFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQI 196 Query: 213 YQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPN 272 + G + ++CL C D YLDI L I QA SV++AL ++PE L+G N Sbjct: 197 FGGYWRSQIKCLHCHGISDTFDPYLDIALDI------QAAQSVQQALEQLVKPEELNGEN 250 Query: 273 QYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTF 332 Y C C ++ A K L +L L LKRF D T K++ + +PE LDM + Sbjct: 251 AYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS-DVTGN---KIDKNVQYPECLDMKLY 306 Query: 333 IDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSGL 392 + +TNSG Sbjct: 307 MS--------------------------------------------QTNSG--------- 313 Query: 393 EKNSLIYELFSVMVHSG-SAAGGHYYACIKSFSDEQWYSFNDQHV------SRITQED-- 443 L+Y L++V+VH+G S GHY++ +K+ + QWY +D V S ++Q+ Sbjct: 314 ---PLVYVLYAVLVHAGWSCHNGHYFSYVKA-QEGQWYKMDDAEVTASSITSVLSQQAYV 369 Query: 444 ---IKKT---HGGSSGSRGYYSSAF-ASSTNAYMLIYRLKDPARNAKFLEVDEYPEHIKN 496 I+K+ S SRG A A T+ LK R+ L+ E EH+ Sbjct: 370 LFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELK---RDHPCLQAPELDEHLVE 426 Query: 497 LVQKERELEE----QEKRQREIERNTCKIK 522 +E L+ QE+ + + E N K++ Sbjct: 427 RATQESTLDHWKFLQEQNKTKPEFNVRKVE 456 >gi|239742291 PREDICTED: hypothetical protein XP_002342477 [Homo sapiens] Length = 530 Score = 89.4 bits (220), Expect = 2e-17 Identities = 111/450 (24%), Positives = 176/450 (39%), Gaps = 102/450 (22%) Query: 101 GLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKK 160 GL N TCY+N+ LQ L TP N + E ++ + +Q + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140 Query: 161 RAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDAL--------EQKWKQTEQADLINEL 212 I+ + + +Q D E DA+ +Q ++ LI+++ Sbjct: 141 HVIQPSQALAA----GFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQI 196 Query: 213 YQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPN 272 + G + ++CL C D YLDI L I QA SV++AL ++PE L+G N Sbjct: 197 FGGYWRSQIKCLHCHGISDTFDPYLDIALDI------QAAQSVQQALEQLVKPEELNGEN 250 Query: 273 QYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTF 332 Y C C ++ A K L +L L LKRF D T K+ + +PE LDM + Sbjct: 251 AYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS-DVTGN---KIAKNVQYPECLDMQPY 306 Query: 333 IDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSGL 392 + +TN+G Sbjct: 307 MS--------------------------------------------QTNTG--------- 313 Query: 393 EKNSLIYELFSVMVHSG-SAAGGHYYACIKSFSDEQWYSFNDQHV------SRITQED-- 443 L+Y L++V+VH+G S GHY++ +K+ + QWY +D V S ++Q+ Sbjct: 314 ---PLVYVLYAVLVHAGWSCHNGHYFSYVKA-QEGQWYKMDDAEVTASSITSVLSQQAYV 369 Query: 444 ---IKKT---HGGSSGSRGYYSSAF-ASSTNAYMLIYRLKDPARNAKFLEVDEYPEHIKN 496 I+K+ S SRG A A T+ LK R+ L+ E EH+ Sbjct: 370 LFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELK---RDHPCLQAPELDEHLVE 426 Query: 497 LVQKERELEE----QEKRQREIERNTCKIK 522 +E L+ QE+ + + E N K++ Sbjct: 427 RATQESTLDHWKFLQEQNKTKPEFNVRKVE 456 >gi|239742278 PREDICTED: hypothetical protein XP_002342472 [Homo sapiens] Length = 530 Score = 89.4 bits (220), Expect = 2e-17 Identities = 111/450 (24%), Positives = 176/450 (39%), Gaps = 102/450 (22%) Query: 101 GLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKK 160 GL N TCY+N+ LQ L TP N + E ++ + +Q + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140 Query: 161 RAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDAL--------EQKWKQTEQADLINEL 212 I+ + + +Q D E DA+ +Q ++ LI+++ Sbjct: 141 HVIQPSQALAA----GFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQI 196 Query: 213 YQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPN 272 + G + ++CL C D YLDI L I QA SV++AL ++PE L+G N Sbjct: 197 FGGYWRSQIKCLHCHGISDTFDPYLDIALDI------QAAQSVQQALEQLVKPEELNGEN 250 Query: 273 QYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTF 332 Y C C ++ A K L +L L LKRF D T K+ + +PE LDM + Sbjct: 251 AYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS-DVTGN---KIAKNVQYPECLDMQPY 306 Query: 333 IDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSGL 392 + +TN+G Sbjct: 307 MS--------------------------------------------QTNTG--------- 313 Query: 393 EKNSLIYELFSVMVHSG-SAAGGHYYACIKSFSDEQWYSFNDQHV------SRITQED-- 443 L+Y L++V+VH+G S GHY++ +K+ + QWY +D V S ++Q+ Sbjct: 314 ---PLVYVLYAVLVHAGWSCHNGHYFSYVKA-QEGQWYKMDDAEVTASSITSVLSQQAYV 369 Query: 444 ---IKKT---HGGSSGSRGYYSSAF-ASSTNAYMLIYRLKDPARNAKFLEVDEYPEHIKN 496 I+K+ S SRG A A T+ LK R+ L+ E EH+ Sbjct: 370 LFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELK---RDHPCLQAPELDEHLVE 426 Query: 497 LVQKERELEE----QEKRQREIERNTCKIK 522 +E L+ QE+ + + E N K++ Sbjct: 427 RATQESTLDHWKFLQEQNKTKPEFNVRKVE 456 >gi|239742289 PREDICTED: hypothetical protein XP_002342476 [Homo sapiens] Length = 530 Score = 89.0 bits (219), Expect = 3e-17 Identities = 111/450 (24%), Positives = 176/450 (39%), Gaps = 102/450 (22%) Query: 101 GLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKK 160 GL N TCY+N+ LQ L TP N + E ++ + +Q + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140 Query: 161 RAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDAL--------EQKWKQTEQADLINEL 212 I+ + + +Q D E DA+ +Q ++ LI+++ Sbjct: 141 HVIQPSQALAA----GFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQI 196 Query: 213 YQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPN 272 + G + ++CL C D YLDI L I QA SV++AL ++PE L+G N Sbjct: 197 FGGYWRSQIKCLHCHGISDTFDPYLDIALDI------QAAQSVQQALEQLVKPEELNGEN 250 Query: 273 QYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTF 332 Y C C ++ A K L +L L LKRF D T K+ + +PE LDM + Sbjct: 251 AYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS-DVTGN---KIAKNVQYPECLDMQPY 306 Query: 333 IDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSGL 392 + +TN+G Sbjct: 307 MS--------------------------------------------QTNTG--------- 313 Query: 393 EKNSLIYELFSVMVHSG-SAAGGHYYACIKSFSDEQWYSFNDQHV------SRITQED-- 443 L+Y L++V+VH+G S GHY++ +K+ + QWY +D V S ++Q+ Sbjct: 314 ---PLVYVLYAVLVHAGWSCHNGHYFSYVKA-QEGQWYKMDDAEVTASSITSVLSQQAYV 369 Query: 444 ---IKKT---HGGSSGSRGYYSSAF-ASSTNAYMLIYRLKDPARNAKFLEVDEYPEHIKN 496 I+K+ S SRG A A T+ LK R+ L+ E EH+ Sbjct: 370 LFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELK---RDHPCLQAPELDEHLVE 426 Query: 497 LVQKERELEE----QEKRQREIERNTCKIK 522 +E L+ QE+ + + E N K++ Sbjct: 427 RATQESTLDHWKFLQEQNKTKPEFNVRKVE 456 >gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sapiens] Length = 359 Score = 86.3 bits (212), Expect = 2e-16 Identities = 68/256 (26%), Positives = 113/256 (44%), Gaps = 36/256 (14%) Query: 99 YVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTS 158 Y GLVN TCY NS+LQ L+ FR + ++ ++ +++ + + L LF + T Sbjct: 27 YFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTC---LADLFHSIATQ 83 Query: 159 KKRA--IETTDVTRSFGWDSS--EAWQQHDVQE----LCRVMFDALEQKWKQTEQ----- 205 KK+ I ++ + + Q D E L + D L+++ KQ +Q Sbjct: 84 KKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLK 143 Query: 206 --------------ADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQA 251 ++E++QG L + RCL C + + +LD+ + + + Sbjct: 144 NGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDV------EQ 197 Query: 252 FASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTT 311 S+ L F E L +Y+CE C K +A+K +R P +L L LKRF + Sbjct: 198 NTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQL 257 Query: 312 MHRIKLNDRMTFPEEL 327 KL+ R+ FP EL Sbjct: 258 HRYTKLSYRVVFPLEL 273 Score = 37.4 bits (85), Expect = 0.093 Identities = 24/81 (29%), Positives = 41/81 (50%), Gaps = 10/81 (12%) Query: 398 IYELFSVMVHSGSAAG-GHYYACIKSFSDEQWYSFNDQHVSRITQEDIKKTHGGSSGSRG 456 +Y+L +V+VH GS GHY +KS W F+D V +I + I++ + G Sbjct: 288 MYDLVAVVVHCGSGPNRGHYITIVKSHG--FWLLFDDDIVEKIDAQAIEEFY-------G 338 Query: 457 YYSSAFASSTNAYMLIYRLKD 477 S +S + Y+L Y+ ++ Sbjct: 339 LTSDISKNSESGYILFYQSRE 359 >gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapiens] Length = 366 Score = 86.3 bits (212), Expect = 2e-16 Identities = 68/256 (26%), Positives = 113/256 (44%), Gaps = 36/256 (14%) Query: 99 YVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTS 158 Y GLVN TCY NS+LQ L+ FR + ++ ++ +++ + + L LF + T Sbjct: 34 YFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTC---LADLFHSIATQ 90 Query: 159 KKRA--IETTDVTRSFGWDSS--EAWQQHDVQE----LCRVMFDALEQKWKQTEQ----- 205 KK+ I ++ + + Q D E L + D L+++ KQ +Q Sbjct: 91 KKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLK 150 Query: 206 --------------ADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQA 251 ++E++QG L + RCL C + + +LD+ + + + Sbjct: 151 NGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDV------EQ 204 Query: 252 FASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTT 311 S+ L F E L +Y+CE C K +A+K +R P +L L LKRF + Sbjct: 205 NTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQL 264 Query: 312 MHRIKLNDRMTFPEEL 327 KL+ R+ FP EL Sbjct: 265 HRYTKLSYRVVFPLEL 280 Score = 37.4 bits (85), Expect = 0.093 Identities = 24/81 (29%), Positives = 41/81 (50%), Gaps = 10/81 (12%) Query: 398 IYELFSVMVHSGSAAG-GHYYACIKSFSDEQWYSFNDQHVSRITQEDIKKTHGGSSGSRG 456 +Y+L +V+VH GS GHY +KS W F+D V +I + I++ + G Sbjct: 295 MYDLVAVVVHCGSGPNRGHYITIVKSHG--FWLLFDDDIVEKIDAQAIEEFY-------G 345 Query: 457 YYSSAFASSTNAYMLIYRLKD 477 S +S + Y+L Y+ ++ Sbjct: 346 LTSDISKNSESGYILFYQSRE 366 >gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens] Length = 1316 Score = 85.1 bits (209), Expect = 4e-16 Identities = 67/243 (27%), Positives = 105/243 (43%), Gaps = 20/243 (8%) Query: 101 GLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKK 160 GL N TC+ N+ LQ L TP N + E ++ + +Q ++ Sbjct: 112 GLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKTCHAEGFCMMCTMQAHITQALSNPG 171 Query: 161 RAI-------ETTDVTRSFGWDSSE---AWQQHDVQELCRVMFDALEQKWKQTEQADLIN 210 I E + R F + + E + Q+ V + + + + + T+ L+ Sbjct: 172 DVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHTQATTLVC 231 Query: 211 ELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDG 270 +++ G L+ V+CL C D YLDI L I+ A SV +AL F++PE LDG Sbjct: 232 QIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIK------AAQSVNKALEQFVKPEQLDG 285 Query: 271 PNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMS 330 N Y C +CKK A K +LTL LKRF K+ + +PE LD+ Sbjct: 286 ENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRF----ANFTGGKIAKDVKYPEYLDIR 341 Query: 331 TFI 333 ++ Sbjct: 342 PYM 344 Score = 37.7 bits (86), Expect = 0.071 Identities = 18/42 (42%), Positives = 28/42 (66%), Gaps = 2/42 (4%) Query: 397 LIYELFSVMVHSG-SAAGGHYYACIKSFSDEQWYSFNDQHVS 437 ++Y L++V+VH+G + GHY+ IK+ S+ WY ND VS Sbjct: 352 IVYVLYAVLVHTGFNCHAGHYFCYIKA-SNGLWYQMNDSIVS 392 >gi|153792150 deubiquitinating enzyme 3 [Homo sapiens] Length = 530 Score = 84.7 bits (208), Expect = 5e-16 Identities = 89/346 (25%), Positives = 136/346 (39%), Gaps = 80/346 (23%) Query: 101 GLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKK 160 GL N TCY N+ LQ L TP N + E ++ + P + +Q S Sbjct: 81 GLQNMGNTCYENASLQCLTYTPPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPG 140 Query: 161 RAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALE--------QKWKQTEQADLINEL 212 I+ + + +Q D E DA++ Q ++ LI+++ Sbjct: 141 HVIQPSQALAA----GFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQI 196 Query: 213 YQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPN 272 + G + ++CL C D YLDI L I QA SV++AL ++PE L+G N Sbjct: 197 FGGCWRSQIKCLHCHGISDTFDPYLDIALDI------QAAQSVKQALEQLVKPEELNGEN 250 Query: 273 QYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTF 332 Y C C ++ A K L +L L LKRF D T KL + +PE L Sbjct: 251 AYHCGLCLQRAPASKTLTLHTSAKVLILVLKRFS-DVTGN---KLAKNVQYPECL----- 301 Query: 333 IDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSGL 392 D++ S Q N+G Sbjct: 302 -DMQPYMSQQ--------------------------------------NTGP-------- 314 Query: 393 EKNSLIYELFSVMVHSG-SAAGGHYYACIKSFSDEQWYSFNDQHVS 437 L+Y L++V+VH+G S GHY++ +K+ + QWY +D V+ Sbjct: 315 ----LVYVLYAVLVHAGWSCHDGHYFSYVKA-QEGQWYKMDDAKVT 355 >gi|169172880 PREDICTED: Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8 [Homo sapiens] Length = 530 Score = 83.6 bits (205), Expect = 1e-15 Identities = 115/468 (24%), Positives = 183/468 (39%), Gaps = 102/468 (21%) Query: 101 GLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKK 160 GL N TCYLN+ LQ L TP N + E ++ + P + +Q S Sbjct: 81 GLQNMGNTCYLNASLQCLTYTPPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPG 140 Query: 161 RAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALE--------QKWKQTEQADLINEL 212 I+ + + +Q D E DA++ Q ++ LI+++ Sbjct: 141 HVIQPSQALAA----GFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQI 196 Query: 213 YQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPN 272 + G + ++CL C D YLDI L I QA SV++AL ++PE L+G N Sbjct: 197 FGGCWRSQIKCLHCHGISDTFDPYLDIALDI------QAAQSVKQALEQLVKPEELNGEN 250 Query: 273 QYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTF 332 Y C C ++ A L +L L LKR + + KL + +PE L Sbjct: 251 AYPCGLCLQRAPASNTLTLHTSAKVLILVLKR----FCDVTGNKLAKNVQYPECL----- 301 Query: 333 IDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSGL 392 D++ S Q N+G Sbjct: 302 -DMQPYMSQQ--------------------------------------NTGP-------- 314 Query: 393 EKNSLIYELFSVMVHSG-SAAGGHYYACIKSFSDEQWYSFNDQHV------SRITQED-- 443 L+Y L++V+VH+G S G+Y++ +K+ + QWY +D V S ++Q+ Sbjct: 315 ----LVYVLYAVLVHAGWSCHNGYYFSYVKA-QEGQWYKMDDAEVTACSITSVLSQQAYV 369 Query: 444 ---IKKT---HGGSSGSRGYYSSAF-ASSTNAYMLIYRLKDPARNAKFLEVDEYPEHIKN 496 I+K+ S SRG A A T+ LK R+ L+V E EH+ Sbjct: 370 LFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELK---RDHPCLQVPELDEHLVE 426 Query: 497 LVQKERELEEQEKRQREIERNTCKIKLFCLHPTKQVMMENKLEVHKDK 544 +E L+ + Q E+N K + F + + + N L +H+ K Sbjct: 427 RATEESTLDHWKFPQ---EQNKMKPE-FNVRKVEGTLPPNVLVIHQSK 470 >gi|169172882 PREDICTED: Ubiquitin carboxyl-terminal hydrolase 17-like protein 3 [Homo sapiens] Length = 530 Score = 83.2 bits (204), Expect = 1e-15 Identities = 116/472 (24%), Positives = 182/472 (38%), Gaps = 110/472 (23%) Query: 101 GLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKK 160 GL N TCY N+ LQ L T N + E ++ + P + +Q S Sbjct: 81 GLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPG 140 Query: 161 RAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALE--------QKWKQTEQADLINEL 212 I+ + S +Q DV E DA++ Q ++ LI+++ Sbjct: 141 HVIQPSQALAS----GFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQI 196 Query: 213 YQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPN 272 + G + ++CL C D YLDI L I QA SV++AL ++PE L+G N Sbjct: 197 FGGCWRSQIKCLHCHGISDTFDPYLDIALDI------QAAQSVKQALEQLVKPEELNGEN 250 Query: 273 QYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTF 332 Y C C ++ A L +L L LKRF + + KL + +PE L Sbjct: 251 AYHCGLCLQRAPASNTLTLHTSAKVLILVLKRF----SDVAGNKLAKNVQYPECL----- 301 Query: 333 IDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSGL 392 D++ S Q N+G Sbjct: 302 -DMQPYMSQQ--------------------------------------NTGP-------- 314 Query: 393 EKNSLIYELFSVMVHSG-SAAGGHYYACIKSFSDEQWYSFNDQHV------SRITQED-- 443 L+Y L++V+VH+G S GHY++ +K+ + QWY +D V S ++Q+ Sbjct: 315 ----LVYVLYAVLVHAGWSCHDGHYFSYVKA-QEGQWYKMDDAEVTVCSITSVLSQQAYV 369 Query: 444 ---IKKT---HGGSSGSRGYYSSAF-ASSTNAYMLIYRLKDPARNAKFLEVDEYPEHIKN 496 I+K+ S SRG A A T+ LK R+ L+ E EH+ Sbjct: 370 LFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELK---RDHPCLQAPELDEHLVE 426 Query: 497 LVQKERELEE----QEKRQREIERNTCKIKLFCLHPTKQVMMENKLEVHKDK 544 +E L+ QE+ + + E N K+ + + N L +H+ K Sbjct: 427 RATQESTLDHWKFLQEQNKTKPEFNVGKV--------EGTLPPNALVIHQSK 470 >gi|169217654 PREDICTED: similar to deubiquitinating enzyme DUB1 [Homo sapiens] Length = 530 Score = 82.0 bits (201), Expect = 3e-15 Identities = 111/450 (24%), Positives = 176/450 (39%), Gaps = 102/450 (22%) Query: 101 GLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKK 160 GL N TCY+N+ LQ L TP N + E ++ + +Q + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140 Query: 161 RAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALE--------QKWKQTEQADLINEL 212 I+ + + +Q D E DA++ Q ++ LI+++ Sbjct: 141 HVIQPSQALAA----GFHRGKQEDAHEFLMFTVDAMKKACLPGHKQADHHSKDTTLIHQI 196 Query: 213 YQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPN 272 + G + ++CL C D YLDI L I QA SV++AL ++PE L+G N Sbjct: 197 FGGYWRSQIKCLHCHGISDTFDPYLDIALDI------QAAQSVQQALEQLVKPEELNGEN 250 Query: 273 QYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTF 332 Y C C ++ A K L +L L LKR F T ++I N + +PE L Sbjct: 251 AYHCGVCLQRAPASKTLTLHTSAKVLILVLKR--FSDVTGNKIAKN--VQYPECL----- 301 Query: 333 IDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSGL 392 D++ S Q N+G Sbjct: 302 -DMQPYMSQQ--------------------------------------NTGP-------- 314 Query: 393 EKNSLIYELFSVMVHSG-SAAGGHYYACIKSFSDEQWYSFNDQHV------SRITQED-- 443 L+Y L++V+VH+G S GHY++ +K+ + QWY +D V S ++Q+ Sbjct: 315 ----LVYVLYAVLVHAGWSCHNGHYFSYVKA-QEGQWYKMDDAEVTASSITSVLSQQAYV 369 Query: 444 ---IKKT---HGGSSGSRGYYSSAF-ASSTNAYMLIYRLKDPARNAKFLEVDEYPEHIKN 496 I+K+ S SRG A A T+ LK R+ L+ E EH+ Sbjct: 370 LFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELK---RDYPSLQAPELDEHLVE 426 Query: 497 LVQKERELEE----QEKRQREIERNTCKIK 522 +E L+ QE+ + + E N K++ Sbjct: 427 RATQESTLDHWKFLQEQNKTKPEFNVRKVE 456 >gi|239758075 PREDICTED: similar to deubiquitinating enzyme DUB1 [Homo sapiens] Length = 530 Score = 81.6 bits (200), Expect = 4e-15 Identities = 111/450 (24%), Positives = 176/450 (39%), Gaps = 102/450 (22%) Query: 101 GLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKK 160 GL N TCY+N+ LQ L TP N + E ++ + +Q + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140 Query: 161 RAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALE--------QKWKQTEQADLINEL 212 I+ + + +Q D E DA++ Q ++ LI+++ Sbjct: 141 HVIQPSQALAA----GFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQI 196 Query: 213 YQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPN 272 + G + ++CL C D YLDI L I QA SV++AL ++PE L+G N Sbjct: 197 FGGYWRSQIKCLHCHGISDTFDPYLDIALDI------QAAQSVQQALEQLVKPEELNGEN 250 Query: 273 QYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTF 332 Y C C ++ A K L +L L LKR F T ++I N + +PE L Sbjct: 251 AYHCGVCLQRAPASKTLTLHTSAKVLILVLKR--FSDVTGNKIAKN--VQYPECL----- 301 Query: 333 IDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSGL 392 D++ S Q N+G Sbjct: 302 -DMQPYMSQQ--------------------------------------NTGP-------- 314 Query: 393 EKNSLIYELFSVMVHSG-SAAGGHYYACIKSFSDEQWYSFNDQHV------SRITQED-- 443 L+Y L++V+VH+G S GHY++ +K+ + QWY +D V S ++Q+ Sbjct: 315 ----LVYVLYAVLVHAGWSCHNGHYFSYVKA-QEGQWYKMDDAEVTASSITSVLSQQAYV 369 Query: 444 ---IKKT---HGGSSGSRGYYSSAF-ASSTNAYMLIYRLKDPARNAKFLEVDEYPEHIKN 496 I+K+ S SRG A A T+ LK R+ L+ E EH+ Sbjct: 370 LFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELK---RDYPCLQAPELDEHLVE 426 Query: 497 LVQKERELEE----QEKRQREIERNTCKIK 522 +E L+ QE+ + + E N K++ Sbjct: 427 RATQESTLDHWKFLQEQNKTKPEFNVRKVE 456 >gi|239742297 PREDICTED: hypothetical protein XP_002342480 [Homo sapiens] Length = 530 Score = 81.6 bits (200), Expect = 4e-15 Identities = 111/450 (24%), Positives = 176/450 (39%), Gaps = 102/450 (22%) Query: 101 GLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKK 160 GL N TCY+N+ LQ L TP N + E ++ + +Q + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140 Query: 161 RAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALE--------QKWKQTEQADLINEL 212 I+ + + +Q D E DA++ Q ++ LI+++ Sbjct: 141 HVIQPSQALAA----GFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQI 196 Query: 213 YQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPN 272 + G + ++CL C D YLDI L I QA SV++AL ++PE L+G N Sbjct: 197 FGGYWRSQIKCLHCHGISDTFDPYLDIALDI------QAAQSVQQALEQLVKPEELNGEN 250 Query: 273 QYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTF 332 Y C C ++ A K L +L L LKR F T ++I N + +PE L Sbjct: 251 AYHCGVCLQRAPASKTLTLHTSAKVLILVLKR--FSDVTGNKIAKN--VQYPECL----- 301 Query: 333 IDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSGL 392 D++ S Q N+G Sbjct: 302 -DMQPYMSQQ--------------------------------------NTGP-------- 314 Query: 393 EKNSLIYELFSVMVHSG-SAAGGHYYACIKSFSDEQWYSFNDQHV------SRITQED-- 443 L+Y L++V+VH+G S GHY++ +K+ + QWY +D V S ++Q+ Sbjct: 315 ----LVYVLYAVLVHAGWSCHNGHYFSYVKA-QEGQWYKMDDAEVTASSITSVLSQQAYV 369 Query: 444 ---IKKT---HGGSSGSRGYYSSAF-ASSTNAYMLIYRLKDPARNAKFLEVDEYPEHIKN 496 I+K+ S SRG A A T+ LK R+ L+ E EH+ Sbjct: 370 LFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELK---RDHPCLQAPELDEHLVE 426 Query: 497 LVQKERELEE----QEKRQREIERNTCKIK 522 +E L+ QE+ + + E N K++ Sbjct: 427 RATQESTLDHWKFLQEQNKTKPEFNVRKVE 456 >gi|239742287 PREDICTED: hypothetical protein XP_002342475 [Homo sapiens] Length = 530 Score = 81.6 bits (200), Expect = 4e-15 Identities = 111/450 (24%), Positives = 176/450 (39%), Gaps = 102/450 (22%) Query: 101 GLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKK 160 GL N TCY+N+ LQ L TP N + E ++ + +Q + Sbjct: 81 GLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG 140 Query: 161 RAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALE--------QKWKQTEQADLINEL 212 I+ + + +Q D E DA++ Q ++ LI+++ Sbjct: 141 HVIQPSQALAA----GFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQI 196 Query: 213 YQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPN 272 + G + ++CL C D YLDI L I QA SV++AL ++PE L+G N Sbjct: 197 FGGYWRSQIKCLHCHGISDTFDPYLDIALDI------QAAQSVQQALEQLVKPEELNGEN 250 Query: 273 QYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTF 332 Y C C ++ A K L +L L LKR F T ++I N + +PE L Sbjct: 251 AYHCGVCLQRAPASKTLTLHTSAKVLILVLKR--FSDVTGNKIAKN--VQYPECL----- 301 Query: 333 IDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSGL 392 D++ S Q N+G Sbjct: 302 -DMQPYMSQQ--------------------------------------NTGP-------- 314 Query: 393 EKNSLIYELFSVMVHSG-SAAGGHYYACIKSFSDEQWYSFNDQHV------SRITQED-- 443 L+Y L++V+VH+G S GHY++ +K+ + QWY +D V S ++Q+ Sbjct: 315 ----LVYVLYAVLVHAGWSCHNGHYFSYVKA-QEGQWYKMDDAEVTAASITSVLSQQAYV 369 Query: 444 ---IKKT---HGGSSGSRGYYSSAF-ASSTNAYMLIYRLKDPARNAKFLEVDEYPEHIKN 496 I+K+ S SRG A A T+ LK R+ L+ E EH+ Sbjct: 370 LFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELK---RDHPCLQAPELDEHLVE 426 Query: 497 LVQKERELEE----QEKRQREIERNTCKIK 522 +E L+ QE+ + + E N K++ Sbjct: 427 RATQESTLDHWKFLQEQNKTKPEFNVRKVE 456 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.131 0.378 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 48,065,840 Number of Sequences: 37866 Number of extensions: 2204239 Number of successful extensions: 8791 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 118 Number of HSP's successfully gapped in prelim test: 140 Number of HSP's that attempted gapping in prelim test: 7638 Number of HSP's gapped (non-prelim): 881 length of query: 1287 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1173 effective length of database: 13,930,794 effective search space: 16340821362 effective search space used: 16340821362 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.