Search of human proteins with 68342036

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|68342036 jumonji domain containing 1C isoform b [Homo
sapiens]
         (2303 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens]    4637   0.0  
gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens]   4625   0.0  
gi|38372909 jumonji domain containing 1B [Homo sapiens]               839   0.0  
gi|226442779 jumonji domain containing 1A [Homo sapiens]              767   0.0  
gi|20357522 jumonji domain containing 1A [Homo sapiens]               767   0.0  
gi|22547204 hairless protein isoform a [Homo sapiens]                 254   7e-67
gi|22547207 hairless protein isoform b [Homo sapiens]                 206   2e-52
gi|87299628 biorientation of chromosomes in cell division 1-like...    62   9e-09
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    58   1e-07
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap...    53   4e-06
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap...    53   4e-06
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            52   9e-06
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            52   9e-06
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]            52   9e-06
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]            52   9e-06
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]            52   9e-06
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            51   1e-05
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]            51   1e-05
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            51   2e-05
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            51   2e-05
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    51   2e-05
gi|20070262 TNF receptor-associated factor 3 interacting protein...    51   2e-05
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    51   2e-05
gi|213385278 TNF receptor-associated factor 3 interacting protei...    50   3e-05
gi|27734775 hypothetical protein LOC286499 [Homo sapiens]              50   3e-05
gi|91982772 mucin 17 [Homo sapiens]                                    50   3e-05
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    49   4e-05
gi|161016767 mucin 21 [Homo sapiens]                                   49   6e-05
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    48   1e-04
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    48   1e-04

>gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens]
          Length = 2303

 Score = 4637 bits (12026), Expect = 0.0
 Identities = 2303/2303 (100%), Positives = 2303/2303 (100%)

Query: 1    MIVMNDQVLEPQNVDPSMVQMTFLDDVVHSLLKGENIGITSRRRSRANQNVNAVHSHYTR 60
            MIVMNDQVLEPQNVDPSMVQMTFLDDVVHSLLKGENIGITSRRRSRANQNVNAVHSHYTR
Sbjct: 1    MIVMNDQVLEPQNVDPSMVQMTFLDDVVHSLLKGENIGITSRRRSRANQNVNAVHSHYTR 60

Query: 61   AQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGE 120
            AQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGE
Sbjct: 61   AQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGE 120

Query: 121  NPKGKNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPEN 180
            NPKGKNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPEN
Sbjct: 121  NPKGKNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPEN 180

Query: 181  ELKNKNTSKINGEEGKPHNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQED 240
            ELKNKNTSKINGEEGKPHNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQED
Sbjct: 181  ELKNKNTSKINGEEGKPHNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQED 240

Query: 241  MIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLE 300
            MIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLE
Sbjct: 241  MIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLE 300

Query: 301  KVAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSV 360
            KVAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSV
Sbjct: 301  KVAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSV 360

Query: 361  TNASSGNDHLNMEKEKYVSYISPLSAVSVMEDKLHKRSPPPETIKSKLNTSVDTHKIKSS 420
            TNASSGNDHLNMEKEKYVSYISPLSAVSVMEDKLHKRSPPPETIKSKLNTSVDTHKIKSS
Sbjct: 361  TNASSGNDHLNMEKEKYVSYISPLSAVSVMEDKLHKRSPPPETIKSKLNTSVDTHKIKSS 420

Query: 421  PSPEVVKPKITHSPDSVKSKATYVNSQATGERRLANKIEHELSRCSFHPIPTRSSTLETT 480
            PSPEVVKPKITHSPDSVKSKATYVNSQATGERRLANKIEHELSRCSFHPIPTRSSTLETT
Sbjct: 421  PSPEVVKPKITHSPDSVKSKATYVNSQATGERRLANKIEHELSRCSFHPIPTRSSTLETT 480

Query: 481  KSPLIIDKNEHFTVYRDPALIGSETGANHISPFLSQHPFPLHSSSHRTCLNPGTHHPALT 540
            KSPLIIDKNEHFTVYRDPALIGSETGANHISPFLSQHPFPLHSSSHRTCLNPGTHHPALT
Sbjct: 481  KSPLIIDKNEHFTVYRDPALIGSETGANHISPFLSQHPFPLHSSSHRTCLNPGTHHPALT 540

Query: 541  PAPHLLAGSSSQTPLPTINTHPLTSGPHHAVHHPHLLPTVLPGVPTASLLGGHPRLESAH 600
            PAPHLLAGSSSQTPLPTINTHPLTSGPHHAVHHPHLLPTVLPGVPTASLLGGHPRLESAH
Sbjct: 541  PAPHLLAGSSSQTPLPTINTHPLTSGPHHAVHHPHLLPTVLPGVPTASLLGGHPRLESAH 600

Query: 601  ASSLSHLALAHQQQQQLLQHQSPHLLGQAHPSASYNQLGLYPIIWQYPNGTHAYSGLGLP 660
            ASSLSHLALAHQQQQQLLQHQSPHLLGQAHPSASYNQLGLYPIIWQYPNGTHAYSGLGLP
Sbjct: 601  ASSLSHLALAHQQQQQLLQHQSPHLLGQAHPSASYNQLGLYPIIWQYPNGTHAYSGLGLP 660

Query: 661  SSKWVHPENAVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPLKIT 720
            SSKWVHPENAVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPLKIT
Sbjct: 661  SSKWVHPENAVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPLKIT 720

Query: 721  AHSSPPLTKTLVDHHKEELERKAFMEPLRSVASTSAKNDLDLNRSQTGKDCHLHRHFVDP 780
            AHSSPPLTKTLVDHHKEELERKAFMEPLRSVASTSAKNDLDLNRSQTGKDCHLHRHFVDP
Sbjct: 721  AHSSPPLTKTLVDHHKEELERKAFMEPLRSVASTSAKNDLDLNRSQTGKDCHLHRHFVDP 780

Query: 781  VLNQLQRPPQETGERLNKYKEEHRRILQESIDVAPFTTKIKGLEGERENYSRVASSSSSP 840
            VLNQLQRPPQETGERLNKYKEEHRRILQESIDVAPFTTKIKGLEGERENYSRVASSSSSP
Sbjct: 781  VLNQLQRPPQETGERLNKYKEEHRRILQESIDVAPFTTKIKGLEGERENYSRVASSSSSP 840

Query: 841  KSHIIKQDMDVERSVSDLYKMKHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYG 900
            KSHIIKQDMDVERSVSDLYKMKHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYG
Sbjct: 841  KSHIIKQDMDVERSVSDLYKMKHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYG 900

Query: 901  DKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQPESEGLVGKIPEHLPHQIASHSVTTF 960
            DKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQPESEGLVGKIPEHLPHQIASHSVTTF
Sbjct: 901  DKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQPESEGLVGKIPEHLPHQIASHSVTTF 960

Query: 961  RNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPIHHSLERKEGSYSSLSPPTLTPVMPVN 1020
            RNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPIHHSLERKEGSYSSLSPPTLTPVMPVN
Sbjct: 961  RNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPIHHSLERKEGSYSSLSPPTLTPVMPVN 1020

Query: 1021 AGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQ 1080
            AGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQ
Sbjct: 1021 AGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQ 1080

Query: 1081 AAMASVIVRPSSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNV 1140
            AAMASVIVRPSSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNV
Sbjct: 1081 AAMASVIVRPSSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNV 1140

Query: 1141 NSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISS 1200
            NSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISS
Sbjct: 1141 NSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISS 1200

Query: 1201 LSNTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDF 1260
            LSNTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDF
Sbjct: 1201 LSNTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDF 1260

Query: 1261 IHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQAS 1320
            IHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQAS
Sbjct: 1261 IHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQAS 1320

Query: 1321 QTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVD 1380
            QTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVD
Sbjct: 1321 QTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVD 1380

Query: 1381 SKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQK 1440
            SKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQK
Sbjct: 1381 SKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQK 1440

Query: 1441 RKGEIEEDLKPNGVLSRSAKERSKLKLQSNSNTGIPRSVLKDWRKVKKLKQTGESFLQDD 1500
            RKGEIEEDLKPNGVLSRSAKERSKLKLQSNSNTGIPRSVLKDWRKVKKLKQTGESFLQDD
Sbjct: 1441 RKGEIEEDLKPNGVLSRSAKERSKLKLQSNSNTGIPRSVLKDWRKVKKLKQTGESFLQDD 1500

Query: 1501 SCCEIGPNLQKCRECRLIRSKKGEEPAHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPDQY 1560
            SCCEIGPNLQKCRECRLIRSKKGEEPAHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPDQY
Sbjct: 1501 SCCEIGPNLQKCRECRLIRSKKGEEPAHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPDQY 1560

Query: 1561 DDEAMSLWTHENFEDDELDIETSKYILDIIGDKFCQLVTSEKTALSWVKKDAKIAWKRAV 1620
            DDEAMSLWTHENFEDDELDIETSKYILDIIGDKFCQLVTSEKTALSWVKKDAKIAWKRAV
Sbjct: 1561 DDEAMSLWTHENFEDDELDIETSKYILDIIGDKFCQLVTSEKTALSWVKKDAKIAWKRAV 1620

Query: 1621 RGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAKERKSSRDKELYAWMKCVKGQPHDH 1680
            RGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAKERKSSRDKELYAWMKCVKGQPHDH
Sbjct: 1621 RGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAKERKSSRDKELYAWMKCVKGQPHDH 1680

Query: 1681 KHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNGVSQSQQQN 1740
            KHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNGVSQSQQQN
Sbjct: 1681 KHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNGVSQSQQQN 1740

Query: 1741 TPPKSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQKAREEKKENKELTLENQIK 1800
            TPPKSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQKAREEKKENKELTLENQIK
Sbjct: 1741 TPPKSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQKAREEKKENKELTLENQIK 1800

Query: 1801 EEREQDNSESPNGRTSPLVSQNNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAP 1860
            EEREQDNSESPNGRTSPLVSQNNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAP
Sbjct: 1801 EEREQDNSESPNGRTSPLVSQNNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAP 1860

Query: 1861 SSKSGRTMPNILDDIIASVVENKIPPSKTSKINVKPELKEEPEESIISAVDENNKLYSDI 1920
            SSKSGRTMPNILDDIIASVVENKIPPSKTSKINVKPELKEEPEESIISAVDENNKLYSDI
Sbjct: 1861 SSKSGRTMPNILDDIIASVVENKIPPSKTSKINVKPELKEEPEESIISAVDENNKLYSDI 1920

Query: 1921 PHSWICEKHILWLKDYKNSSNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGD 1980
            PHSWICEKHILWLKDYKNSSNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGD
Sbjct: 1921 PHSWICEKHILWLKDYKNSSNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGD 1980

Query: 1981 HQADLLNCKDSIISNANVKEFWDGFEEVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPAR 2040
            HQADLLNCKDSIISNANVKEFWDGFEEVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPAR
Sbjct: 1981 HQADLLNCKDSIISNANVKEFWDGFEEVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPAR 2040

Query: 2041 YEDLLKSLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSAYGVVAAKDHDIGTTNLHI 2100
            YEDLLKSLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSAYGVVAAKDHDIGTTNLHI
Sbjct: 2041 YEDLLKSLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSAYGVVAAKDHDIGTTNLHI 2100

Query: 2101 EVSDVVNILVYVGIAKGNGILSKAGILKKFEEEDLDDILRKRLKDSSEIPGALWHIYAGK 2160
            EVSDVVNILVYVGIAKGNGILSKAGILKKFEEEDLDDILRKRLKDSSEIPGALWHIYAGK
Sbjct: 2101 EVSDVVNILVYVGIAKGNGILSKAGILKKFEEEDLDDILRKRLKDSSEIPGALWHIYAGK 2160

Query: 2161 DVDKIREFLQKISKEQGLEVLPEHDPIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDA 2220
            DVDKIREFLQKISKEQGLEVLPEHDPIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDA
Sbjct: 2161 DVDKIREFLQKISKEQGLEVLPEHDPIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDA 2220

Query: 2221 IVLPAGALHQVQNFHSCIQVTEDFVSPEHLVESFHLTQELRLLKEEINYDDKLQVKNILY 2280
            IVLPAGALHQVQNFHSCIQVTEDFVSPEHLVESFHLTQELRLLKEEINYDDKLQVKNILY
Sbjct: 2221 IVLPAGALHQVQNFHSCIQVTEDFVSPEHLVESFHLTQELRLLKEEINYDDKLQVKNILY 2280

Query: 2281 HAVKEMVRALKIHEDEVEDMEEN 2303
            HAVKEMVRALKIHEDEVEDMEEN
Sbjct: 2281 HAVKEMVRALKIHEDEVEDMEEN 2303


>gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens]
          Length = 2540

 Score = 4625 bits (11997), Expect = 0.0
 Identities = 2303/2321 (99%), Positives = 2303/2321 (99%), Gaps = 18/2321 (0%)

Query: 1    MIVMNDQVLEPQNVDPSMVQMTFLDDVVHSLLKGENIGITSRRRSRANQNVNAVHSHYTR 60
            MIVMNDQVLEPQNVDPSMVQMTFLDDVVHSLLKGENIGITSRRRSRANQNVNAVHSHYTR
Sbjct: 220  MIVMNDQVLEPQNVDPSMVQMTFLDDVVHSLLKGENIGITSRRRSRANQNVNAVHSHYTR 279

Query: 61   AQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGE 120
            AQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGE
Sbjct: 280  AQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGE 339

Query: 121  NPKGKNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPEN 180
            NPKGKNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPEN
Sbjct: 340  NPKGKNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPEN 399

Query: 181  ELKNKNTSKINGEEGKPHNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQED 240
            ELKNKNTSKINGEEGKPHNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQED
Sbjct: 400  ELKNKNTSKINGEEGKPHNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQED 459

Query: 241  MIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLE 300
            MIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLE
Sbjct: 460  MIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLE 519

Query: 301  KVAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSV 360
            KVAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSV
Sbjct: 520  KVAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSV 579

Query: 361  TNASSGNDHLNMEKEKYVSYISPLSAVSVMEDKLHKRSPPPETIKSKLNTSVDTHKIKSS 420
            TNASSGNDHLNMEKEKYVSYISPLSAVSVMEDKLHKRSPPPETIKSKLNTSVDTHKIKSS
Sbjct: 580  TNASSGNDHLNMEKEKYVSYISPLSAVSVMEDKLHKRSPPPETIKSKLNTSVDTHKIKSS 639

Query: 421  PSPEVVKPKITHSPDSVKSKATYVNSQATGERRLANKIEHELSRCSFHPIPTRSSTLETT 480
            PSPEVVKPKITHSPDSVKSKATYVNSQATGERRLANKIEHELSRCSFHPIPTRSSTLETT
Sbjct: 640  PSPEVVKPKITHSPDSVKSKATYVNSQATGERRLANKIEHELSRCSFHPIPTRSSTLETT 699

Query: 481  KSPLIIDKNEHFTVYRDPALIGSETGANHISPFLSQHPFPLHSSSHRTCLNPGTHHPALT 540
            KSPLIIDKNEHFTVYRDPALIGSETGANHISPFLSQHPFPLHSSSHRTCLNPGTHHPALT
Sbjct: 700  KSPLIIDKNEHFTVYRDPALIGSETGANHISPFLSQHPFPLHSSSHRTCLNPGTHHPALT 759

Query: 541  PAPHLLAGSSSQTPLPTINTHPLTSGPHHAVHHPHLLPTVLPGVPTASLLGGHPRLESAH 600
            PAPHLLAGSSSQTPLPTINTHPLTSGPHHAVHHPHLLPTVLPGVPTASLLGGHPRLESAH
Sbjct: 760  PAPHLLAGSSSQTPLPTINTHPLTSGPHHAVHHPHLLPTVLPGVPTASLLGGHPRLESAH 819

Query: 601  ASSLSHLALAHQQQQQLLQHQSPHLLGQAHPSASYNQLGLYPIIWQYPNGTHAYSGLGLP 660
            ASSLSHLALAHQQQQQLLQHQSPHLLGQAHPSASYNQLGLYPIIWQYPNGTHAYSGLGLP
Sbjct: 820  ASSLSHLALAHQQQQQLLQHQSPHLLGQAHPSASYNQLGLYPIIWQYPNGTHAYSGLGLP 879

Query: 661  SSKWVHPENAVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPLKIT 720
            SSKWVHPENAVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPLKIT
Sbjct: 880  SSKWVHPENAVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPLKIT 939

Query: 721  AHSSPPLTKTLVDHHKEELERKAFMEPLRSVASTSAKNDLDLNRSQTGKDCHLHRHFVDP 780
            AHSSPPLTKTLVDHHKEELERKAFMEPLRSVASTSAKNDLDLNRSQTGKDCHLHRHFVDP
Sbjct: 940  AHSSPPLTKTLVDHHKEELERKAFMEPLRSVASTSAKNDLDLNRSQTGKDCHLHRHFVDP 999

Query: 781  VLNQLQRPPQETGERLNKYKEEHRRILQESIDVAPFTTKIKGLEGERENYSRVASSSSSP 840
            VLNQLQRPPQETGERLNKYKEEHRRILQESIDVAPFTTKIKGLEGERENYSRVASSSSSP
Sbjct: 1000 VLNQLQRPPQETGERLNKYKEEHRRILQESIDVAPFTTKIKGLEGERENYSRVASSSSSP 1059

Query: 841  KSHIIKQDMDVERSVSDLYKMKHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYG 900
            KSHIIKQDMDVERSVSDLYKMKHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYG
Sbjct: 1060 KSHIIKQDMDVERSVSDLYKMKHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYG 1119

Query: 901  DKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQPESEGLVGKIPEHLPHQIASHSVTTF 960
            DKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQPESEGLVGKIPEHLPHQIASHSVTTF
Sbjct: 1120 DKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQPESEGLVGKIPEHLPHQIASHSVTTF 1179

Query: 961  RNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPIHHSLERKEGSYSSLSPPTLTPVMPVN 1020
            RNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPIHHSLERKEGSYSSLSPPTLTPVMPVN
Sbjct: 1180 RNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPIHHSLERKEGSYSSLSPPTLTPVMPVN 1239

Query: 1021 AGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQ 1080
            AGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQ
Sbjct: 1240 AGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQ 1299

Query: 1081 AAMASVIVRPSSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNV 1140
            AAMASVIVRPSSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNV
Sbjct: 1300 AAMASVIVRPSSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNV 1359

Query: 1141 NSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISS 1200
            NSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISS
Sbjct: 1360 NSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISS 1419

Query: 1201 LSNTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDF 1260
            LSNTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDF
Sbjct: 1420 LSNTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDF 1479

Query: 1261 IHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQAS 1320
            IHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQAS
Sbjct: 1480 IHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQAS 1539

Query: 1321 QTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVD 1380
            QTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVD
Sbjct: 1540 QTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVD 1599

Query: 1381 SKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQK 1440
            SKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQK
Sbjct: 1600 SKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQK 1659

Query: 1441 RKGEIEEDLKPNGVLSRSAKERSKLKLQSNSNTGIPRSVLKDWRKVKKLKQTGESFLQDD 1500
            RKGEIEEDLKPNGVLSRSAKERSKLKLQSNSNTGIPRSVLKDWRKVKKLKQTGESFLQDD
Sbjct: 1660 RKGEIEEDLKPNGVLSRSAKERSKLKLQSNSNTGIPRSVLKDWRKVKKLKQTGESFLQDD 1719

Query: 1501 SCCEIGPNLQKCRECRLIRSKKGEEPAHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPDQY 1560
            SCCEIGPNLQKCRECRLIRSKKGEEPAHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPDQY
Sbjct: 1720 SCCEIGPNLQKCRECRLIRSKKGEEPAHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPDQY 1779

Query: 1561 DDEAMSLWTHENFEDDELDIETSKYILDIIGDKFCQLVTSEKTALSWVKKDAKIAWKRAV 1620
            DDEAMSLWTHENFEDDELDIETSKYILDIIGDKFCQLVTSEKTALSWVKKDAKIAWKRAV
Sbjct: 1780 DDEAMSLWTHENFEDDELDIETSKYILDIIGDKFCQLVTSEKTALSWVKKDAKIAWKRAV 1839

Query: 1621 RGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAKERKSSRDKELYAWMKCVKGQPHDH 1680
            RGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAKERKSSRDKELYAWMKCVKGQPHDH
Sbjct: 1840 RGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAKERKSSRDKELYAWMKCVKGQPHDH 1899

Query: 1681 KHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNGVSQ----- 1735
            KHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNGVSQ     
Sbjct: 1900 KHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNGVSQVLQNV 1959

Query: 1736 -------------SQQQNTPPKSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQK 1782
                         SQQQNTPPKSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQK
Sbjct: 1960 LNHSNKISLCMPESQQQNTPPKSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQK 2019

Query: 1783 AREEKKENKELTLENQIKEEREQDNSESPNGRTSPLVSQNNEQGSTLRDLLTTTAGKLRV 1842
            AREEKKENKELTLENQIKEEREQDNSESPNGRTSPLVSQNNEQGSTLRDLLTTTAGKLRV
Sbjct: 2020 AREEKKENKELTLENQIKEEREQDNSESPNGRTSPLVSQNNEQGSTLRDLLTTTAGKLRV 2079

Query: 1843 GSTDAGIAFAPVYSMGAPSSKSGRTMPNILDDIIASVVENKIPPSKTSKINVKPELKEEP 1902
            GSTDAGIAFAPVYSMGAPSSKSGRTMPNILDDIIASVVENKIPPSKTSKINVKPELKEEP
Sbjct: 2080 GSTDAGIAFAPVYSMGAPSSKSGRTMPNILDDIIASVVENKIPPSKTSKINVKPELKEEP 2139

Query: 1903 EESIISAVDENNKLYSDIPHSWICEKHILWLKDYKNSSNWKLFKECWKQGQPAVVSGVHK 1962
            EESIISAVDENNKLYSDIPHSWICEKHILWLKDYKNSSNWKLFKECWKQGQPAVVSGVHK
Sbjct: 2140 EESIISAVDENNKLYSDIPHSWICEKHILWLKDYKNSSNWKLFKECWKQGQPAVVSGVHK 2199

Query: 1963 KMNISLWKAESISLDFGDHQADLLNCKDSIISNANVKEFWDGFEEVSKRQKNKSGETVVL 2022
            KMNISLWKAESISLDFGDHQADLLNCKDSIISNANVKEFWDGFEEVSKRQKNKSGETVVL
Sbjct: 2200 KMNISLWKAESISLDFGDHQADLLNCKDSIISNANVKEFWDGFEEVSKRQKNKSGETVVL 2259

Query: 2023 KLKDWPSGEDFKTMMPARYEDLLKSLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSA 2082
            KLKDWPSGEDFKTMMPARYEDLLKSLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSA
Sbjct: 2260 KLKDWPSGEDFKTMMPARYEDLLKSLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSA 2319

Query: 2083 YGVVAAKDHDIGTTNLHIEVSDVVNILVYVGIAKGNGILSKAGILKKFEEEDLDDILRKR 2142
            YGVVAAKDHDIGTTNLHIEVSDVVNILVYVGIAKGNGILSKAGILKKFEEEDLDDILRKR
Sbjct: 2320 YGVVAAKDHDIGTTNLHIEVSDVVNILVYVGIAKGNGILSKAGILKKFEEEDLDDILRKR 2379

Query: 2143 LKDSSEIPGALWHIYAGKDVDKIREFLQKISKEQGLEVLPEHDPIRDQSWYVNKKLRQRL 2202
            LKDSSEIPGALWHIYAGKDVDKIREFLQKISKEQGLEVLPEHDPIRDQSWYVNKKLRQRL
Sbjct: 2380 LKDSSEIPGALWHIYAGKDVDKIREFLQKISKEQGLEVLPEHDPIRDQSWYVNKKLRQRL 2439

Query: 2203 LEEYGVRTCTLIQFLGDAIVLPAGALHQVQNFHSCIQVTEDFVSPEHLVESFHLTQELRL 2262
            LEEYGVRTCTLIQFLGDAIVLPAGALHQVQNFHSCIQVTEDFVSPEHLVESFHLTQELRL
Sbjct: 2440 LEEYGVRTCTLIQFLGDAIVLPAGALHQVQNFHSCIQVTEDFVSPEHLVESFHLTQELRL 2499

Query: 2263 LKEEINYDDKLQVKNILYHAVKEMVRALKIHEDEVEDMEEN 2303
            LKEEINYDDKLQVKNILYHAVKEMVRALKIHEDEVEDMEEN
Sbjct: 2500 LKEEINYDDKLQVKNILYHAVKEMVRALKIHEDEVEDMEEN 2540


>gi|38372909 jumonji domain containing 1B [Homo sapiens]
          Length = 1761

 Score =  839 bits (2167), Expect = 0.0
 Identities = 475/1137 (41%), Positives = 667/1137 (58%), Gaps = 106/1137 (9%)

Query: 1242 SKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQTL---SASLP 1298
            S   S    +SG S +   +  K       A  +  S++S    +  K + L   + S  
Sbjct: 647  SPFSSFASQASGSSSSATTVTSK------VAPSWPESHSSADSASLAKKKPLFITTDSSK 700

Query: 1299 LDSTVICSTINKA----NSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGN 1354
            L S V+ S +       +++GNG++S  +  +    ++   L+    E++ T       N
Sbjct: 701  LVSGVLGSALTSGGPSLSAMGNGRSSSPTS-SLTQPIEMPTLSSSPTEERPTVGPGQQDN 759

Query: 1355 SV----SEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKAKRTYESGSESG 1410
             +    S +    S   ++S +   Q +      V ++  D++    +      + S+  
Sbjct: 760  PLLKTFSNVFGRHSGGFLSSPADFSQENKAPFEAVKRFSLDERSLACRQDSDSSTNSDLS 819

Query: 1411 DSDESESKSEQRTKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSRS---AKERSKLKL 1467
            D  +SE + + +T  +  P +             +   L PNG  S      K + K   
Sbjct: 820  DLSDSEEQLQAKTGLKGIPEH-------------LMGKLGPNGERSAELLLGKSKGKQAP 866

Query: 1468 QSNSNTG---IPRSVLKDWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLIRSKKGE 1524
            +    T    + +SVLKD  KVKKLKQ+GE FLQD SC  + P+L KCRECRL R +K +
Sbjct: 867  KGRPRTAPLKVGQSVLKDVSKVKKLKQSGEPFLQDGSCINVAPHLHKCRECRLERYRKFK 926

Query: 1525 EPAH--SPVFCRFYYFRRLSFSKNGVVRIDGFSSPDQYDDEAMSLWTHENFEDDELDIET 1582
            E     S V CRF++FRRL F++ GV+R++GF SP Q D +AM+LW   +   + +D+ET
Sbjct: 927  EQEQDDSTVACRFFHFRRLIFTRKGVLRVEGFLSPQQSDPDAMNLWIPSSSLAEGIDLET 986

Query: 1583 SKYILDIIGDKFCQLVTSEKTALSWVKKDAKIAWKRAVRGVREMCDACEATLFNIHWVCQ 1642
            SKYIL  +GD+FCQLV SEK A+  V+   K+AWKRAVRGVREMCD CE TLFNIHWVC+
Sbjct: 987  SKYILANVGDQFCQLVMSEKEAMMMVEPHQKVAWKRAVRGVREMCDVCETTLFNIHWVCR 1046

Query: 1643 KCGFVVCLDCYKAK------ERKSSRDKELYAWMKCVKGQPHDHKHLMPTQIIPGSVLTD 1696
            KCGF VCLDCY+ +      E +   D+E+++W+KC KGQ H+ ++LMPTQIIPG+ L +
Sbjct: 1047 KCGFGVCLDCYRLRKSRPRSETEEMGDEEVFSWLKCAKGQSHEPENLMPTQIIPGTALYN 1106

Query: 1697 LLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNGVSQSQQQNTPPKSEK----NGGSS 1752
            + D +H  R K+GIK++C C ++QN  V      NG+SQ    N    S      +GG  
Sbjct: 1107 IGDMVHAARGKWGIKANCPCISRQNKSVLRPAVTNGMSQLPSINPSASSGNETTFSGGGG 1166

Query: 1753 P---------------------ESDVGTDNKLTPPESQ---------------SPLHWLA 1776
            P                     E  + TD+  +   S+               S LHWLA
Sbjct: 1167 PAPVTTPEPDHVPKADSTDIRSEEPLKTDSSASNSNSELKAIRPPCPDTAPPSSALHWLA 1226

Query: 1777 DLAEQKAREEKKENKEL-TLENQIKEEREQDNSESPNGRTSPLV-------------SQN 1822
            DLA QKA+EE KE   L ++ N+        +S +   + SPL              S N
Sbjct: 1227 DLATQKAKEETKEAGSLRSVLNKESHSPFGLDSFNSTAKVSPLTPKLFNSLLLGPTASNN 1286

Query: 1823 NEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAPSSKSGRTMPNILDDIIASVVEN 1882
              +GS+LRDLL +  GKL     D GI F PV+S  +   KS  ++PN LD IIASVVEN
Sbjct: 1287 KTEGSSLRDLLHSGPGKLPQTPLDTGIPFPPVFSTSSAGVKSKASLPNFLDHIIASVVEN 1346

Query: 1883 KIPPSKTSKINVKPELKEEPEESIISAVDENNKLYSDIPHSWICEKHILWLKDYKNSSNW 1942
            K     + +     + ++E +E ++      N L     HSW+C+  +L L D  N +NW
Sbjct: 1347 KKTSDASKRACNLTDTQKEVKEMVMGL----NVLDPHTSHSWLCDGRLLCLHDPSNKNNW 1402

Query: 1943 KLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQADLLNCKD-SIISNANVKEF 2001
            K+F+ECWKQGQP +VSGVHKK+   LWK E+ S +FGD   DL+NC++ +IIS+  V++F
Sbjct: 1403 KIFRECWKQGQPVLVSGVHKKLKSELWKPEAFSQEFGDQDVDLVNCRNCAIISDVKVRDF 1462

Query: 2002 WDGFEEVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPARYEDLLKSLPLPEYCNPEGKFN 2061
            WDGFE + KR +++ G+ +VLKLKDWP GEDF+ MMP R+EDL+++LPLPEY   +G+ N
Sbjct: 1463 WDGFEIICKRLRSEDGQPMVLKLKDWPPGEDFRDMMPTRFEDLMENLPLPEYTKRDGRLN 1522

Query: 2062 LASHLPGFFVRPDLGPRLCSAYGVVAAKDHDIGTTNLHIEVSDVVNILVYVGIAKGNGIL 2121
            LAS LP +FVRPDLGP++ +AYG++ A+D  +GTTNLH++VSD VN++VYVGI  G G  
Sbjct: 1523 LASRLPSYFVRPDLGPKMYNAYGLITAEDRRVGTTNLHLDVSDAVNVMVYVGIPIGEGAH 1582

Query: 2122 SKAGILKKFEEEDLDDILRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKISKEQGLEVL 2181
             +  +LK  +E D D++ ++R+ D  E PGALWHIYA KD +KIRE L+K+ +EQG E  
Sbjct: 1583 DEE-VLKTIDEGDADEVTKQRIHDGKEKPGALWHIYAAKDAEKIRELLRKVGEEQGQENP 1641

Query: 2182 PEHDPIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDAIVLPAGALHQVQNFHSCIQVT 2241
            P+HDPI DQSWY+++ LR+RL EEYGV+   ++QFLGDA+ +PAGA HQV N +SCI+V 
Sbjct: 1642 PDHDPIHDQSWYLDQTLRKRLYEEYGVQGWAIVQFLGDAVFIPAGAPHQVHNLYSCIKVA 1701

Query: 2242 EDFVSPEHLVESFHLTQELR-LLKEEINYDDKLQVKNILYHAVKEMVRALKIHEDEV 2297
            EDFVSPEH+   F LTQE R L     N++DKLQVKNI+YHAVK+ V  LK HE ++
Sbjct: 1702 EDFVSPEHVKHCFRLTQEFRHLSNTHTNHEDKLQVKNIIYHAVKDAVGTLKAHESKL 1758


>gi|226442779 jumonji domain containing 1A [Homo sapiens]
          Length = 1321

 Score =  767 bits (1981), Expect = 0.0
 Identities = 424/1019 (41%), Positives = 609/1019 (59%), Gaps = 104/1019 (10%)

Query: 1308 INKANSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNL 1367
            ++K++ +G G     ++P       K   T+        N++E+   +++ + K C   L
Sbjct: 369  LSKSSQIGTGDLKILTEP-------KGSCTQPKTNTDQENRLESVPQALTGLPKEC---L 418

Query: 1368 IASTSSDIQNSVDSKIIVDKYVK-----DDKVNRRKAKRTYESGSESGDSDESESKSEQR 1422
                SS  +  + +   + K+++      D  N  + K    S S +  S +        
Sbjct: 419  PTKASSKAELEIANPPELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGK-------- 470

Query: 1423 TKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSRSAKERSKLKLQSNSNTGIPRSVLKD 1482
             K +P     + QN    ++  ++ D       + S   RS  K+Q   N    +SVL D
Sbjct: 471  -KVEPSALACRSQN---LKESSVKVD-------NESCCSRSNNKIQ---NAPSRKSVLTD 516

Query: 1483 WRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLIRSKKG-EEPAHSPVFCRFYYFRRL 1541
              K+KKL+Q+GE+F+QDDSC  I   L KCRECRL   +K  E+   SPVFCRF++FRRL
Sbjct: 517  PAKLKKLQQSGEAFVQDDSCVNIVAQLPKCRECRLDSLRKDKEQQKDSPVFCRFFHFRRL 576

Query: 1542 SFSKNGVVRIDGFSSPDQYDDEAMSLWTHENFEDDELDIETSKYILDIIGDKFCQLVTSE 1601
             F+K+GV+R++GF +P++YD+EA+ LW         +D++T+KYIL  IGD FCQ+V SE
Sbjct: 577  QFNKHGVLRVEGFLTPNKYDNEAIGLWLPLTKNVVGIDLDTAKYILANIGDHFCQMVISE 636

Query: 1602 KTALSWVKKDAKIAWKRAVRGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAKERKSS 1661
            K A+S ++   ++AWKRAV+GVREMCD C+ T+FN+HWVC +CGF VC+DCY+ K +   
Sbjct: 637  KEAMSTIEPHRQVAWKRAVKGVREMCDVCDTTIFNLHWVCPRCGFGVCVDCYRMKRKNCQ 696

Query: 1662 RDK--ELYAWMKCVKGQPHDHKHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTN- 1718
            +    + ++W+KCVK Q H+ ++LMPTQIIPG  L D+ D +H++R K+GIK++C C+N 
Sbjct: 697  QGAAYKTFSWLKCVKSQIHEPENLMPTQIIPGKALYDVGDIVHSVRAKWGIKANCPCSNR 756

Query: 1719 --------------KQNLQVGNFPTMNGVSQSQQQNTPPKSEKNGGSSPESDVGTDNKLT 1764
                          KQ    G  PT+  V Q       P +   GG +     G+  K  
Sbjct: 757  QFKLFSKPASKEDLKQTSLAGEKPTLGAVLQQNPSVLEPAAV--GGEAASKPAGS-MKPA 813

Query: 1765 PPESQSPLHWLADLAEQKAREEKKENKELT--LENQIK-----EEREQDNSESPNGRTSP 1817
             P S SPL+WLADL      +E KE +     L+N+IK         + ++      ++ 
Sbjct: 814  CPASTSPLNWLADLTSGNVNKENKEKQPTMPILKNEIKCLPPLPPLSKSSTVLHTFNSTI 873

Query: 1818 LVSQNNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAPSSKSGRTMPNILDDIIA 1877
            L   +N     LR+LL ++ GK     T+ G+                +  P ILDDI A
Sbjct: 874  LTPVSNNNSGFLRNLLNSSTGK-----TENGL----------------KNTPKILDDIFA 912

Query: 1878 SVVENKIPPSKTSKINVKPELKEEPEESIISAVDENNKLYSDIPHSWICEKHILWLKDYK 1937
            S+V+NK     TS ++ +P+              + + L  D PH W+C+  +L L+D  
Sbjct: 913  SLVQNKT----TSDLSKRPQ----------GLTIKPSILGFDTPHYWLCDNRLLCLQDPN 958

Query: 1938 NSSNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQADLLNCK-DSIISNA 1996
            N SNW +F+ECWKQGQP +VSGVH K+N  LWK ES   +FG+ + DL+NC+ + II+ A
Sbjct: 959  NKSNWNVFRECWKQGQPVMVSGVHHKLNSELWKPESFRKEFGEQEVDLVNCRTNEIITGA 1018

Query: 1997 NVKEFWDGFEEVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPARYEDLLKSLPLPEYCNP 2056
             V +FWDGFE+V  R KN+  E +VLKLKDWP GEDF+ MMP+R++DL+ ++PLPEY   
Sbjct: 1019 TVGDFWDGFEDVPNRLKNEK-EPMVLKLKDWPPGEDFRDMMPSRFDDLMANIPLPEYTRR 1077

Query: 2057 EGKFNLASHLPGFFVRPDLGPRLCSAYGVVAAKDHDIGTTNLHIEVSDVVNILVYVGIAK 2116
            +GK NLAS LP +FVRPDLGP++ +AYG++  +D   GTTNLH++VSD  N++VYVGI K
Sbjct: 1078 DGKLNLASRLPNYFVRPDLGPKMYNAYGLITPEDRKYGTTNLHLDVSDAANVMVYVGIPK 1137

Query: 2117 GNGILSKAGILKKFEEEDLDDILRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKISKEQ 2176
            G     +  +LK  ++ D D++  KR  +  E PGALWHIYA KD +KIREFL+K+S+EQ
Sbjct: 1138 GQ-CEQEEEVLKTIQDGDSDELTIKRFIEGKEKPGALWHIYAAKDTEKIREFLKKVSEEQ 1196

Query: 2177 GLEVLPEHDPIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDAIVLPAGALHQVQNFHS 2236
            G E   +HDPI DQSWY+++ LR+RL +EYGV+   ++QFLGD + +PAGA HQV N +S
Sbjct: 1197 GQENPADHDPIHDQSWYLDRSLRKRLHQEYGVQGWAIVQFLGDVVFIPAGAPHQVHNLYS 1256

Query: 2237 CIQVTEDFVSPEHLVESFHLTQELRLLKE-EINYDDKLQVKNILYHAVKEMVRALKIHE 2294
            CI+V EDFVSPEH+   F LTQE R L +   N++DKLQVKN++YHAVK+ V  LK  E
Sbjct: 1257 CIKVAEDFVSPEHVKHCFWLTQEFRYLSQTHTNHEDKLQVKNVIYHAVKDAVAMLKASE 1315


>gi|20357522 jumonji domain containing 1A [Homo sapiens]
          Length = 1321

 Score =  767 bits (1981), Expect = 0.0
 Identities = 424/1019 (41%), Positives = 609/1019 (59%), Gaps = 104/1019 (10%)

Query: 1308 INKANSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNL 1367
            ++K++ +G G     ++P       K   T+        N++E+   +++ + K C   L
Sbjct: 369  LSKSSQIGTGDLKILTEP-------KGSCTQPKTNTDQENRLESVPQALTGLPKEC---L 418

Query: 1368 IASTSSDIQNSVDSKIIVDKYVK-----DDKVNRRKAKRTYESGSESGDSDESESKSEQR 1422
                SS  +  + +   + K+++      D  N  + K    S S +  S +        
Sbjct: 419  PTKASSKAELEIANPPELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGK-------- 470

Query: 1423 TKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSRSAKERSKLKLQSNSNTGIPRSVLKD 1482
             K +P     + QN    ++  ++ D       + S   RS  K+Q   N    +SVL D
Sbjct: 471  -KVEPSALACRSQN---LKESSVKVD-------NESCCSRSNNKIQ---NAPSRKSVLTD 516

Query: 1483 WRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLIRSKKG-EEPAHSPVFCRFYYFRRL 1541
              K+KKL+Q+GE+F+QDDSC  I   L KCRECRL   +K  E+   SPVFCRF++FRRL
Sbjct: 517  PAKLKKLQQSGEAFVQDDSCVNIVAQLPKCRECRLDSLRKDKEQQKDSPVFCRFFHFRRL 576

Query: 1542 SFSKNGVVRIDGFSSPDQYDDEAMSLWTHENFEDDELDIETSKYILDIIGDKFCQLVTSE 1601
             F+K+GV+R++GF +P++YD+EA+ LW         +D++T+KYIL  IGD FCQ+V SE
Sbjct: 577  QFNKHGVLRVEGFLTPNKYDNEAIGLWLPLTKNVVGIDLDTAKYILANIGDHFCQMVISE 636

Query: 1602 KTALSWVKKDAKIAWKRAVRGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAKERKSS 1661
            K A+S ++   ++AWKRAV+GVREMCD C+ T+FN+HWVC +CGF VC+DCY+ K +   
Sbjct: 637  KEAMSTIEPHRQVAWKRAVKGVREMCDVCDTTIFNLHWVCPRCGFGVCVDCYRMKRKNCQ 696

Query: 1662 RDK--ELYAWMKCVKGQPHDHKHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTN- 1718
            +    + ++W+KCVK Q H+ ++LMPTQIIPG  L D+ D +H++R K+GIK++C C+N 
Sbjct: 697  QGAAYKTFSWLKCVKSQIHEPENLMPTQIIPGKALYDVGDIVHSVRAKWGIKANCPCSNR 756

Query: 1719 --------------KQNLQVGNFPTMNGVSQSQQQNTPPKSEKNGGSSPESDVGTDNKLT 1764
                          KQ    G  PT+  V Q       P +   GG +     G+  K  
Sbjct: 757  QFKLFSKPASKEDLKQTSLAGEKPTLGAVLQQNPSVLEPAAV--GGEAASKPAGS-MKPA 813

Query: 1765 PPESQSPLHWLADLAEQKAREEKKENKELT--LENQIK-----EEREQDNSESPNGRTSP 1817
             P S SPL+WLADL      +E KE +     L+N+IK         + ++      ++ 
Sbjct: 814  CPASTSPLNWLADLTSGNVNKENKEKQPTMPILKNEIKCLPPLPPLSKSSTVLHTFNSTI 873

Query: 1818 LVSQNNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAPSSKSGRTMPNILDDIIA 1877
            L   +N     LR+LL ++ GK     T+ G+                +  P ILDDI A
Sbjct: 874  LTPVSNNNSGFLRNLLNSSTGK-----TENGL----------------KNTPKILDDIFA 912

Query: 1878 SVVENKIPPSKTSKINVKPELKEEPEESIISAVDENNKLYSDIPHSWICEKHILWLKDYK 1937
            S+V+NK     TS ++ +P+              + + L  D PH W+C+  +L L+D  
Sbjct: 913  SLVQNKT----TSDLSKRPQ----------GLTIKPSILGFDTPHYWLCDNRLLCLQDPN 958

Query: 1938 NSSNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQADLLNCK-DSIISNA 1996
            N SNW +F+ECWKQGQP +VSGVH K+N  LWK ES   +FG+ + DL+NC+ + II+ A
Sbjct: 959  NKSNWNVFRECWKQGQPVMVSGVHHKLNSELWKPESFRKEFGEQEVDLVNCRTNEIITGA 1018

Query: 1997 NVKEFWDGFEEVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPARYEDLLKSLPLPEYCNP 2056
             V +FWDGFE+V  R KN+  E +VLKLKDWP GEDF+ MMP+R++DL+ ++PLPEY   
Sbjct: 1019 TVGDFWDGFEDVPNRLKNEK-EPMVLKLKDWPPGEDFRDMMPSRFDDLMANIPLPEYTRR 1077

Query: 2057 EGKFNLASHLPGFFVRPDLGPRLCSAYGVVAAKDHDIGTTNLHIEVSDVVNILVYVGIAK 2116
            +GK NLAS LP +FVRPDLGP++ +AYG++  +D   GTTNLH++VSD  N++VYVGI K
Sbjct: 1078 DGKLNLASRLPNYFVRPDLGPKMYNAYGLITPEDRKYGTTNLHLDVSDAANVMVYVGIPK 1137

Query: 2117 GNGILSKAGILKKFEEEDLDDILRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKISKEQ 2176
            G     +  +LK  ++ D D++  KR  +  E PGALWHIYA KD +KIREFL+K+S+EQ
Sbjct: 1138 GQ-CEQEEEVLKTIQDGDSDELTIKRFIEGKEKPGALWHIYAAKDTEKIREFLKKVSEEQ 1196

Query: 2177 GLEVLPEHDPIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDAIVLPAGALHQVQNFHS 2236
            G E   +HDPI DQSWY+++ LR+RL +EYGV+   ++QFLGD + +PAGA HQV N +S
Sbjct: 1197 GQENPADHDPIHDQSWYLDRSLRKRLHQEYGVQGWAIVQFLGDVVFIPAGAPHQVHNLYS 1256

Query: 2237 CIQVTEDFVSPEHLVESFHLTQELRLLKE-EINYDDKLQVKNILYHAVKEMVRALKIHE 2294
            CI+V EDFVSPEH+   F LTQE R L +   N++DKLQVKN++YHAVK+ V  LK  E
Sbjct: 1257 CIKVAEDFVSPEHVKHCFWLTQEFRYLSQTHTNHEDKLQVKNVIYHAVKDAVAMLKASE 1315


>gi|22547204 hairless protein isoform a [Homo sapiens]
          Length = 1189

 Score =  254 bits (649), Expect = 7e-67
 Identities = 225/764 (29%), Positives = 336/764 (43%), Gaps = 113/764 (14%)

Query: 1497 LQDDSCCEIGPNLQKCRECRLIRSKKGEEPAHSPVFCRFYYFRRLSFSKNGVVRIDGFSS 1556
            LQD  C  +   L +C+ C     + G    HS    R      L   ++          
Sbjct: 482  LQDIPCLALPAKLAQCQSCAQAAGEGGGHACHSQQVRRSPLGGELQQEEDTATNSSSEEG 541

Query: 1557 PDQYDDEAMSLWTHENFEDDELDIETSKYILDIIGDKFCQLVTSEKTALSWVKKDAK-IA 1615
            P    D  +S                +K++L  +GD+ C+L+  E+ AL+W +++ +  A
Sbjct: 542  PGSGPDSRLSTGL-------------AKHLLSGLGDRLCRLLRREREALAWAQREGQGPA 588

Query: 1616 WKRAVRGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAKERKSSRDKELYAWM---KC 1672
                  G+   C  C   LFN HW C +C   +C+ C +      +R+K  +      +C
Sbjct: 589  VTEDSPGIPRCCSRCHHGLFNTHWRCPRCSHRLCVACGRVAGTGRAREKAGFQEQSAEEC 648

Query: 1673 VKGQPHDHKHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNG 1732
             +   H    LM TQ +    L +L  AMH +  K+ I+ HC C     +     P   G
Sbjct: 649  TQEAGHAACSLMLTQFVSSQALAELSTAMHQVWVKFDIRGHCPCQADARVWA---PGDAG 705

Query: 1733 VSQSQQQNTPPKSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQKAREEKKENKE 1792
              +   Q TPP        +P+     D   T                +  +EE  ++ E
Sbjct: 706  QQKESTQKTPP--------TPQPSCNGDTHRT----------------KSIKEETPDSAE 741

Query: 1793 LTLENQIKEEREQDNSESPNGRTSPLVSQNNEQGSTLRDLLTTTAGKLRVGSTDAGIAFA 1852
               E++              GR  PL   +      L +LL +TA KL +G     +AFA
Sbjct: 742  TPAEDRA-------------GR-GPLPCPS------LCELLASTAVKLCLGHERIHMAFA 781

Query: 1853 PVYSMGAPSSKSGRTMPNILDDIIASVVENKIPPSKTSKINVKPELKEEPEESIISAVDE 1912
            PV     P+  S   + NILD IIA VVE KI           P L+  P          
Sbjct: 782  PV----TPALPSDDRITNILDSIIAQVVERKIQEKALG-----PGLRAGP---------- 822

Query: 1913 NNKLYSDIPHSWICEK-----HILWLKDYKNSSN--WKLFKECWKQGQPAVVSGVHKKMN 1965
              +    +P S +  +      +LWL++ +      + LF+E W+QGQP +VSG+ + + 
Sbjct: 823  GLRKGLGLPLSPVRPRLPPPGALLWLQEPQPCPRRGFHLFQEHWRQGQPVLVSGIQRTLQ 882

Query: 1966 ISLWKAESISLDFGDHQADLLNCKDSIISNANVKEFWDGFEEVSKRQKNKSGETVVLKLK 2025
             +LW  E++    G  QA L        S+     FW+GF     R K+  G   VL L 
Sbjct: 883  GNLWGTEALGALGGQVQA-LSPLGPPQPSSLGSTTFWEGFSWPELRPKSDEGS--VLLLH 939

Query: 2026 DWPSGEDFKTMMPARYEDLLKSLPLPEYCNPEGKFNLASHLP-GFFVRPDLGPRLCSAYG 2084
                 ED      +R E+L  SLPLPEYC   GK NLAS+LP G  +RP L P+L +AYG
Sbjct: 940  RALGDED-----TSRVENLAASLPLPEYCALHGKLNLASYLPPGLALRP-LEPQLWAAYG 993

Query: 2085 VVAAKDHDIGTTNLHIEVSDVVNILVYVGIAKGNGILSKAGILKKFEEEDLDDILRKRLK 2144
            V   + H +GT NL +EV+D+V+ILV+          ++   L   + E L         
Sbjct: 994  VSPHRGH-LGTKNLCVEVADLVSILVHADTPLPAWHRAQKDFLSGLDGEGL-------WS 1045

Query: 2145 DSSEIPGALWHIYAGKDVDKIREFLQKISKEQGLEVLPEHDPIRDQSWYVNKKLRQRLLE 2204
              S++   +WH++  +D  +IR FLQ +    G   L   +P    S Y++  LR+RL E
Sbjct: 1046 PGSQV-STVWHVFRAQDAQRIRRFLQMVCPA-GAGAL---EPGAPGSCYLDAGLRRRLRE 1100

Query: 2205 EYGVRTCTLIQFLGDAIVLPAGALHQVQNFHSCIQVTEDFVSPE 2248
            E+GV   TL+Q  G+A+++PAGA HQVQ   S + VT+ F+SPE
Sbjct: 1101 EWGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTVSVTQHFLSPE 1144



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 15/32 (46%), Positives = 20/32 (62%)

Query: 1311 ANSVGNGQASQTSQPNYHTKLKKAWLTRHSEE 1342
            +  V      +   P++HTKLKK WLTRHSE+
Sbjct: 359  SEEVNKASGPRACPPSHHTKLKKTWLTRHSEQ 390


>gi|22547207 hairless protein isoform b [Homo sapiens]
          Length = 1134

 Score =  206 bits (524), Expect = 2e-52
 Identities = 195/694 (28%), Positives = 293/694 (42%), Gaps = 112/694 (16%)

Query: 1497 LQDDSCCEIGPNLQKCRECRLIRSKKGEEPAHSPVFCRFYYFRRLSFSKNGVVRIDGFSS 1556
            LQD  C  +   L +C+ C     + G    HS    R      L   ++          
Sbjct: 482  LQDIPCLALPAKLAQCQSCAQAAGEGGGHACHSQQVRRSPLGGELQQEEDTATNSSSEEG 541

Query: 1557 PDQYDDEAMSLWTHENFEDDELDIETSKYILDIIGDKFCQLVTSEKTALSWVKKDAK-IA 1615
            P    D  +S                +K++L  +GD+ C+L+  E+ AL+W +++ +  A
Sbjct: 542  PGSGPDSRLSTGL-------------AKHLLSGLGDRLCRLLRREREALAWAQREGQGPA 588

Query: 1616 WKRAVRGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAKERKSSRDKELYAWM---KC 1672
                  G+   C  C   LFN HW C +C   +C+ C +      +R+K  +      +C
Sbjct: 589  VTEDSPGIPRCCSRCHHGLFNTHWRCPRCSHRLCVACGRVAGTGRAREKAGFQEQSAEEC 648

Query: 1673 VKGQPHDHKHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNG 1732
             +   H    LM TQ +    L +L  AMH +  K+ I+ HC C     +     P   G
Sbjct: 649  TQEAGHAACSLMLTQFVSSQALAELSTAMHQVWVKFDIRGHCPCQADARVWA---PGDAG 705

Query: 1733 VSQSQQQNTPPKSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQKAREEKKENKE 1792
              +   Q TPP        +P+     D   T                +  +EE  ++ E
Sbjct: 706  QQKESTQKTPP--------TPQPSCNGDTHRT----------------KSIKEETPDSAE 741

Query: 1793 LTLENQIKEEREQDNSESPNGRTSPLVSQNNEQGSTLRDLLTTTAGKLRVGSTDAGIAFA 1852
               E++              GR  PL   +      L +LL +TA KL +G     +AFA
Sbjct: 742  TPAEDRA-------------GR-GPLPCPS------LCELLASTAVKLCLGHERIHMAFA 781

Query: 1853 PVYSMGAPSSKSGRTMPNILDDIIASVVENKIPPSKTSKINVKPELKEEPEESIISAVDE 1912
            PV     P+  S   + NILD IIA VVE KI           P L+  P          
Sbjct: 782  PV----TPALPSDDRITNILDSIIAQVVERKIQEKALG-----PGLRAGP---------- 822

Query: 1913 NNKLYSDIPHSWICEK-----HILWLKDYKNSSN--WKLFKECWKQGQPAVVSGVHKKMN 1965
              +    +P S +  +      +LWL++ +      + LF+E W+QGQP +VSG+ + + 
Sbjct: 823  GLRKGLGLPLSPVRPRLPPPGALLWLQEPQPCPRRGFHLFQEHWRQGQPVLVSGIQRTLQ 882

Query: 1966 ISLWKAESISLDFGDHQADLLNCKDSIISNANVKEFWDGFEEVSKRQKNKSGETVVLKLK 2025
             +LW  E++    G  QA L        S+     FW+GF     R K+  G   VL L 
Sbjct: 883  GNLWGTEALGALGGQVQA-LSPLGPPQPSSLGSTTFWEGFSWPELRPKSDEGS--VLLLH 939

Query: 2026 DWPSGEDFKTMMPARYEDLLKSLPLPEYCNPEGKFNLASHL-PGFFVRPDLGPRLCSAYG 2084
                 ED      +R E+L  SLPLPEYC   GK NLAS+L PG  +RP L P+L +AYG
Sbjct: 940  RALGDED-----TSRVENLAASLPLPEYCALHGKLNLASYLPPGLALRP-LEPQLWAAYG 993

Query: 2085 VVAAKDHDIGTTNLHIEVSDVVNILVYVGIAKGNGILSKAGILKKFEEEDLDDILRKRLK 2144
            V   + H +GT NL +EV+D+V+ILV+          ++   L   + E L         
Sbjct: 994  VSPHRGH-LGTKNLCVEVADLVSILVHADTPLPAWHRAQKDFLSGLDGEGL-------WS 1045

Query: 2145 DSSEIPGALWHIYAGKDVDKIREFLQKISKEQGL 2178
              S++   +WH++  +D  +IR FLQ +   QGL
Sbjct: 1046 PGSQV-STVWHVFRAQDAQRIRRFLQMV---QGL 1075



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 15/32 (46%), Positives = 20/32 (62%)

Query: 1311 ANSVGNGQASQTSQPNYHTKLKKAWLTRHSEE 1342
            +  V      +   P++HTKLKK WLTRHSE+
Sbjct: 359  SEEVNKASGPRACPPSHHTKLKKTWLTRHSEQ 390


>gi|87299628 biorientation of chromosomes in cell division 1-like
            [Homo sapiens]
          Length = 3051

 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 90/422 (21%), Positives = 172/422 (40%), Gaps = 51/422 (12%)

Query: 85   QQQRSIRPNKRKGSDSSIPDEEKMKE------EKYDYISRGENPKGKN---KHLMNKRRK 135
            Q++   R  KR+   S I  EE  K+      EK+      E P  K+   K + + + K
Sbjct: 668  QEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEK 727

Query: 136  PEED----EKKLNMK-RLRTDNVSDFSESSDSENSNK--RIIDN----------SSEQKP 178
            PE +    E KL++K + + D +    + ++  +S K  ++ +N          SS+ K 
Sbjct: 728  PEREKTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDDKT 787

Query: 179  ENELKNKNTSKIN--GEEGKPHNNE--KAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVD 234
            E + K++N  K++  G++GKP +    K  E   K +     ++  +K   E + R+S D
Sbjct: 788  ERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKAEHKSRRSSD 847

Query: 235  TQLQEDMIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVSRPP-------TP 287
            +++Q+D  + S +        S      +C+MD T+    L  E+ V +           
Sbjct: 848  SKIQKDS-LGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEE 906

Query: 288  KCVIDITNDTNLEKVAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWV 347
            K V+   + T  ++V    +      T Q   P     K++  N    +   K  D+ + 
Sbjct: 907  KLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFE 966

Query: 348  SDVVK--VDLTQSSVTNASSGNDH---LNMEKEKYVSYISPLSAVSVMEDKLHKRSPPPE 402
               V+  ++   SS  +    + H   L + KEKY S     S       +L ++     
Sbjct: 967  ETGVEPVLETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTST------RLERKLSDGH 1020

Query: 403  TIKSKLNTSVDTHKIKSSPSPEVVKPKITHSPDSVKSKATYVNSQATGERRLANKIEHEL 462
              +S  ++S D  K   + S +    ++  S +  +  ++ +  + +  RRL       L
Sbjct: 1021 KSRSLKHSSKDIKKKDENKSDDKDGKEVDSSHEKARGNSSLMEKKLS--RRLCENRRGSL 1078

Query: 463  SR 464
            S+
Sbjct: 1079 SQ 1080



 Score = 45.8 bits (107), Expect = 5e-04
 Identities = 64/268 (23%), Positives = 100/268 (37%), Gaps = 64/268 (23%)

Query: 1270 LAAAQYKSSNASETEPNAIKNQTL-----------SASLPLDSTVICSTINKANSVGNGQ 1318
            LA   +K   +  T P+  K  T            SA++  D+  I  TI   N   +  
Sbjct: 159  LATLNHKEEGSGNTAPDDEKPDTSLITQGVPTPGPSANVANDAMSILETITSLNQEASAA 218

Query: 1319 ASQT----------------SQPNYHTKLKKAWLTRHSEE--DKNTNKMENSGNSVSEII 1360
             + T                SQP   T   K    R SE+  DK  +  ++ G  +    
Sbjct: 219  RASTETSNAKTSERASKKLPSQPTTDTSTDKE---RTSEDMADKEKSTADSGGEGLETAP 275

Query: 1361 K-------PCSVNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKAKRTYESGSESGDSD 1413
            K       PC V  I + + +  N     I+++K V+ +  + +K K T +   +   ++
Sbjct: 276  KSEEFSDLPCPVEEIKNYTKEHNNL----ILLNKDVQQES-SEQKNKSTDKGEKKPDSNE 330

Query: 1414 ESESKSEQRTKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSRSAKERSKLKLQSNSNT 1473
            + E K E++ K + K  + KK  D QK K E +             KE   LKL S  N+
Sbjct: 331  KGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQA----------KEKEVESLKLPSEKNS 380

Query: 1474 GIPRSVLKDWRKVKKLKQTGESFLQDDS 1501
                       K K ++ T E F   DS
Sbjct: 381  ----------NKAKTVEGTKEDFSLIDS 398



 Score = 39.7 bits (91), Expect = 0.035
 Identities = 93/455 (20%), Positives = 171/455 (37%), Gaps = 94/455 (20%)

Query: 72  SQAAVPKQN-THQQQQQRSIRP------NKRKGSDSSIPDEEKMKEEKYDYISRGENPKG 124
           SQ   PK N T + Q ++++        +K +GS ++ PD+EK        I++G    G
Sbjct: 136 SQVVDPKINHTFRPQVEKAVHEFLATLNHKEEGSGNTAPDDEK---PDTSLITQGVPTPG 192

Query: 125 KNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRI-----IDNSSEQKPE 179
            + ++ N      E    LN +       ++ S +  SE ++K++      D S++++  
Sbjct: 193 PSANVANDAMSILETITSLNQEASAARASTETSNAKTSERASKKLPSQPTTDTSTDKERT 252

Query: 180 NE---LKNKNTSKINGE-----------------------EGKPHNN------------- 200
           +E    K K+T+   GE                         K HNN             
Sbjct: 253 SEDMADKEKSTADSGGEGLETAPKSEEFSDLPCPVEEIKNYTKEHNNLILLNKDVQQESS 312

Query: 201 EKAGEETLKNSQPPWDQIQEDKKHEEAEK--------RKSVDTQLQEDMIIHSSEQSTVS 252
           E+  + T K  + P    + ++K E+ EK        +KS DTQ  +D      E+    
Sbjct: 313 EQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKD------EKQAKE 366

Query: 253 DHNSNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLEKVAQENSSTFGL 312
               +  LP E N +K  T+E   KE F         +ID   D  L  +   +  T  L
Sbjct: 367 KEVESLKLPSEKNSNKAKTVE-GTKEDF--------SLIDSDVD-GLTDITVSSVHTSDL 416

Query: 313 QTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSVTNASSGND---- 368
            + ++      D++  +  +  +E  +  SD     +  K + T++  +++S G      
Sbjct: 417 SSFEE------DTEEEVVTSDSMEEGEITSDD---EEKNKQNKTKTQTSDSSEGKTKSVR 467

Query: 369 HLNMEKE-KYVSYISPLSAVSVMEDKLHKRSPPPETIKSKLNTSVDTHKIKSSPSPEVVK 427
           H  + K   Y  Y S       +E +  ++S   E  +  L   ++  K++     +  K
Sbjct: 468 HAYVHKPYLYSKYYSDSDDELTVEQR--RQSIAKEKEERLLRRQINREKLEEKRKQKAEK 525

Query: 428 PKITHSPDSVKSKATYVNSQATGERRLANKIEHEL 462
            K + +    +S      S        A +I+  L
Sbjct: 526 TKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVL 560



 Score = 36.6 bits (83), Expect = 0.29
 Identities = 68/341 (19%), Positives = 122/341 (35%), Gaps = 56/341 (16%)

Query: 1143 DSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISSLS 1202
            +S+   SEKN              S +++  +  TD+  S+  T+ +SS+          
Sbjct: 370  ESLKLPSEKNSNKAKTVEGTKEDFSLIDSDVDGLTDITVSSVHTSDLSSFE--------- 420

Query: 1203 NTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDFI- 1261
                  T  E V+S S+       +E ++++        +KT +  Q S    G T  + 
Sbjct: 421  ----EDTEEEVVTSDSM-------EEGEITSDDEEKNKQNKTKT--QTSDSSEGKTKSVR 467

Query: 1262 HLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQASQ 1321
            H   HK  L +  Y  S+   T    ++ +  S +   +  ++   IN+       +  Q
Sbjct: 468  HAYVHKPYLYSKYYSDSDDELT----VEQRRQSIAKEKEERLLRRQINREKL--EEKRKQ 521

Query: 1322 TSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDS 1381
             ++    +K K    +    E+ +T  +E     + E++K   V             ++ 
Sbjct: 522  KAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKV-------------LEK 568

Query: 1382 KIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQKR 1441
            K+ + K        R+K  R  E  S+     E +SK   +T    +        +L K 
Sbjct: 569  KVALSK-------KRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKEL-KH 620

Query: 1442 KGEIEEDLKPNGVLSRSA------KERSKLKLQSNSNTGIP 1476
                 E  KP   LS S       K  SKL+ +    T  P
Sbjct: 621  VHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTP 661



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 34/154 (22%), Positives = 67/154 (43%), Gaps = 14/154 (9%)

Query: 91   RPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNK-HLMNKRRKPEEDEKKLNMKRLR 149
            + N    S  S+  + K  EE+  ++     PK K K H ++   +P+++   L+ +   
Sbjct: 2743 KDNAEAISGHSVEADPKEVEEEERHM-----PKRKRKQHYLSSEDEPDDNPDVLDSRIET 2797

Query: 150  TDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKPHNNEKAGEETLK 209
                   +E  D++  N R ++   +   E    N  TS++  E+ +  ++E  GE+  +
Sbjct: 2798 AQRQCPETEPHDTKEENSRDLEELPKTSSET---NSTTSRVMEEKDEYSSSETTGEKPEQ 2854

Query: 210  NSQPPWDQIQEDK----KHEEAEKRK-SVDTQLQ 238
            N        +ED+    K +    RK  V+T L+
Sbjct: 2855 NDDDTIKSQEEDQPIIIKRKRGRPRKYPVETTLK 2888



 Score = 33.9 bits (76), Expect = 1.9
 Identities = 24/76 (31%), Positives = 41/76 (53%), Gaps = 6/76 (7%)

Query: 1396 RRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVL 1455
            RR+ ++   S + S D++ SE +  +R K    P   KK+ +  + + E EED +P+G  
Sbjct: 2945 RRRGRKPKRSLTVSDDAESSEPE-RKRQKSVSDPVEDKKEQESDEEEEEEEED-EPSGAT 3002

Query: 1456 SRSA----KERSKLKL 1467
            +RS      +RSK +L
Sbjct: 3003 TRSTTRSEAQRSKTQL 3018



 Score = 33.1 bits (74), Expect = 3.2
 Identities = 62/376 (16%), Positives = 131/376 (34%), Gaps = 27/376 (7%)

Query: 83  QQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKPEEDEKK 142
           ++++++  +  K+        D +K+K+EK       E+ K  ++   NK +  E  ++ 
Sbjct: 333 ERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKED 392

Query: 143 LNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKPHNNEK 202
            ++     D ++D + SS   +      +++ E+   ++  +    +I  ++ + +   K
Sbjct: 393 FSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSD--SMEEGEITSDDEEKNKQNK 450

Query: 203 AGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLPQ 262
              +T  +S+     ++    H+     K       +D +     + +++      LL +
Sbjct: 451 TKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSD--SDDELTVEQRRQSIAKEKEERLLRR 508

Query: 263 ECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLEKVAQENSSTFGLQTLQKMDPNV 322
           + N +K         EK  S           T       V  E SST      + ++P  
Sbjct: 509 QINREKLEEKRKQKAEKTKSSK---------TKGQGRSSVDLEESST------KSLEPKA 553

Query: 323 SDSKHSIANAKFLE-------TAKKDSDQSWVSDVVKVDLTQSSVTNASSGNDHLNMEKE 375
           +  K  +   K LE         KKDS     +   K    + S     + ++H   EK 
Sbjct: 554 ARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKT-SEHCEKEKI 612

Query: 376 KYVSYISPLSAVSVMEDKLHKRSPPPETIKSKLNTSVDTHKIKSSPSPEVVKPKITHSPD 435
                +  + A S       + S     +    N S    + K   S  V+   +    D
Sbjct: 613 SSSKELKHVHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIMEGVQEETD 672

Query: 436 SVKSKATYVNSQATGE 451
           +   K     S+   E
Sbjct: 673 TRDVKRQVERSEICTE 688



 Score = 32.3 bits (72), Expect = 5.5
 Identities = 39/184 (21%), Positives = 69/184 (37%), Gaps = 25/184 (13%)

Query: 35   ENIGITSRRRSRANQNVNAVHSHYTRAQANSPRPAMNSQAAVPKQNTHQQQ--QQRSIRP 92
            E +  TS   +     V      Y+ ++    +P  N    +  Q   Q    +++  RP
Sbjct: 2819 EELPKTSSETNSTTSRVMEEKDEYSSSETTGEKPEQNDDDTIKSQEEDQPIIIKRKRGRP 2878

Query: 93   NKR------KGSDSSIPD------EEKMKEEKYDYISRGENPKGKNKHLMNKRRKPEEDE 140
             K       K  D S  D      E+     K   +   E+ K +  +L  +    ++ E
Sbjct: 2879 RKYPVETTLKMKDDSKTDTGIVTVEQSPSSSKLKVMQTDESNK-ETANLQERSISNDDGE 2937

Query: 141  KKL-------NMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGE 193
            +K+         K  R+  VSD +ESS+ E   ++ + +  E K E E   +   +   E
Sbjct: 2938 EKIVTSVRRRGRKPKRSLTVSDDAESSEPERKRQKSVSDPVEDKKEQESDEEEEEE---E 2994

Query: 194  EGKP 197
            E +P
Sbjct: 2995 EDEP 2998


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 80/382 (20%), Positives = 159/382 (41%), Gaps = 19/382 (4%)

Query: 1037 EPKDSQANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKT 1096
            E  DS  +  S S  S ++    N++ S          SS    ++ +S      SS  +
Sbjct: 700  ESSDSSDSSDSDSSDS-SDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS-----DSSNSS 753

Query: 1097 DSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSEKNFQAV 1156
            DS  +   +S    S  SS  +  +D    +++ ++      + +S+S  + +  +    
Sbjct: 754  DSSDSSD-SSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDS 812

Query: 1157 SQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISS-LSNTILASTSSECVS 1215
            S  S   S  S+ ++  +  +D   S+  + S  S  GS+  SS  S++  +S SS+   
Sbjct: 813  SDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD 872

Query: 1216 SKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQY 1275
            S + S         + S ++  + +S+ + S    SS  S ++D           ++   
Sbjct: 873  SSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD-----------SSNSS 921

Query: 1276 KSSNASETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAW 1335
             SS +S +  N+  + + ++S   DS+   ++ + +NS  +  +S +S  N       + 
Sbjct: 922  DSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN 981

Query: 1336 LTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYVKDDKVN 1395
             +  S+   +++  ++S +S S      S +  +S SSD  NS DS    D     D  +
Sbjct: 982  SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD 1041

Query: 1396 RRKAKRTYESGSESGDSDESES 1417
               +  + +S   S  SD S+S
Sbjct: 1042 SSDSSDSSDSSDSSNSSDSSDS 1063



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 80/384 (20%), Positives = 149/384 (38%), Gaps = 16/384 (4%)

Query: 1043 ANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAM 1102
            +N  +SS+ S +     +++ S          SS    ++ +S     S S  +DS  + 
Sbjct: 660  SNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSS 719

Query: 1103 QLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVP 1162
               S D  S  SS  +  ++    +++ ++      + +SDS ++ S+ +  + S  S  
Sbjct: 720  NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNS-SDSSDSSDSSDSSD 778

Query: 1163 SSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISS---LSNTILASTSSECVSSKSV 1219
            SS  S  N   N+     +S +  +S SS       SS    SN+  +S SS+   S + 
Sbjct: 779  SSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNS 838

Query: 1220 SQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSN 1279
            S           S +     + S   S    SS  S ++D            ++    SN
Sbjct: 839  SDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSD------------SSDSSDSN 886

Query: 1280 ASETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWLTRH 1339
             S    ++  +   S S   DS+    + + +NS  + ++S +S  +  +    +  +  
Sbjct: 887  ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSD 946

Query: 1340 SEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKA 1399
            S +  N++   NS +S +      S +  +S SS+  +S DS    D     D  N   +
Sbjct: 947  SSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDS 1006

Query: 1400 KRTYESGSESGDSDESESKSEQRT 1423
              + +S   S  SD S S     +
Sbjct: 1007 SDSSDSSDSSNSSDSSNSSDSSNS 1030



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 74/382 (19%), Positives = 155/382 (40%), Gaps = 26/382 (6%)

Query: 1091 SSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSE 1150
            +SS+ +DS  +    S D  S  SS  +  +D    +++ ++      +  SDS  ++S+
Sbjct: 575  NSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDS--SDSKSDSSKSESD 632

Query: 1151 KNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISSLSNTILASTS 1210
             +       S  S+   + +   ++ +   ++++D++  S    S   S  SN+  +S S
Sbjct: 633  SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692

Query: 1211 SECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAAL 1270
            S+  S+ S S   +   +   S ++     SS + S    SS  S ++D           
Sbjct: 693  SDS-SNSSESSDSSDSSDSDSSDSSD----SSNSNSSDSDSSNSSDSSD----------- 736

Query: 1271 AAAQYKSSNASETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQPNYHTK 1330
                  SSN+S++  ++  + +  +S   DS+    + + ++S  +  +S +S  N  + 
Sbjct: 737  ------SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSN 790

Query: 1331 LKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYVK 1390
               +  + +S +  N++   +S +S        S +  +S SSD  NS DS    D    
Sbjct: 791  SSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDG 850

Query: 1391 DDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQKRKGEIEEDLK 1450
             D  +  ++  +  + S+S DS +S + S+         +     +       + +    
Sbjct: 851  SDSDSSNRSDSS--NSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDS 908

Query: 1451 PNGVLSRSAKERSKLKLQSNSN 1472
             N   S  +   S     SNS+
Sbjct: 909  SNSSDSSDSSNSSDSSESSNSS 930



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 57/278 (20%), Positives = 118/278 (42%), Gaps = 2/278 (0%)

Query: 1141 NSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISS 1200
            +SDS  + S  +  +    S  SS   + ++  ++ +   + ++D++  S    S+  SS
Sbjct: 568  DSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSS 627

Query: 1201 LSNTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDF 1260
             S +  + + S+  SS S S   +   +   S+ +  +  SS +      SS    +   
Sbjct: 628  KSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSS 687

Query: 1261 IHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQAS 1320
                   ++ ++    SS++S+++ +   + + S S   DS+    + + +NS  +  +S
Sbjct: 688  DSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS 747

Query: 1321 QTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSV-SEIIKPCSVNLIASTSSDIQNSV 1379
             +S  +  +    +  +  S +  +++   +S NS  S      S +  +S SSD  NS 
Sbjct: 748  DSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSS 807

Query: 1380 DSKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESES 1417
            DS    D     D  N   +  + +S   S  SD S+S
Sbjct: 808  DSSDSSDS-SDSDSSNSSDSSNSSDSSDSSNSSDSSDS 844



 Score = 48.5 bits (114), Expect = 7e-05
 Identities = 76/381 (19%), Positives = 159/381 (41%), Gaps = 18/381 (4%)

Query: 1043 ANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAM 1102
            +N   SS+ S +     ++N S          SS    ++ +S     SS +   S  + 
Sbjct: 909  SNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS----NSSDSSNSSDSSN 964

Query: 1103 QLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVP 1162
               S D  S  SS  ++ +D    +++ ++         SDS  + +  +    S  S  
Sbjct: 965  SSDSSDSNSSDSSDSSNSSDSSDSSDSSDS---------SDSSDSSNSSDSSDSSDSSDS 1015

Query: 1163 SSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISSLSNTILASTSSECVSSKSVSQP 1222
            S+   + N+  ++ +   + ++D++  S    S   S  SN+  +S SS+   S   S  
Sbjct: 1016 SNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1075

Query: 1223 VAQKQECKVSTTAPVTLAS-SKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNAS 1281
                   + S ++  + +S S   S    SS  S ++D        ++ ++    SS++S
Sbjct: 1076 SDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSD--SSDSSDSSNSSDSSDSSDSS 1133

Query: 1282 ETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQP-NYHTKLKKAWLTRHS 1340
            ++  ++  + +  +S   DS+    + + ++S  +  +S +S   N       +  +  S
Sbjct: 1134 DSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1193

Query: 1341 EEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKAK 1400
            +   +++  ++S +S S      S +  +S SSD  +S +S    D     D  N   + 
Sbjct: 1194 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSS 1253

Query: 1401 RTYESGSESGDS-DESESKSE 1420
             + +S   + DS DES+S+S+
Sbjct: 1254 DSSDSSDSTSDSNDESDSQSK 1274



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 55/250 (22%), Positives = 104/250 (41%), Gaps = 19/250 (7%)

Query: 1174 NTKTDVITSAADTTSVSSWGGSEVISSLSNTILASTSSECVSSKSVSQPVAQKQECKVST 1233
            N K+D     +D++   S       S  SN+  +S SS+  SS S S   +   +   S 
Sbjct: 537  NDKSDSGKGKSDSSDSDS-------SDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSD 589

Query: 1234 TAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQTL 1293
            ++    + S   S    SS  S ++D       K+  + ++  SS++     ++  N + 
Sbjct: 590  SSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSD 649

Query: 1294 SASLPLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSG 1353
            S+    D++    + N +NS  +  +S +S  +  +    +  +  S+   ++N  E+S 
Sbjct: 650  SS----DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNS--SDSSDSSDSSNSSESSD 703

Query: 1354 NS------VSEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKAKRTYESGS 1407
            +S       S+     + N   S SS+  +S DS    D     D  N   +  + +S +
Sbjct: 704  SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN 763

Query: 1408 ESGDSDESES 1417
             S  SD S+S
Sbjct: 764  SSDSSDSSDS 773



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 72/404 (17%), Positives = 146/404 (36%), Gaps = 24/404 (5%)

Query: 63  ANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENP 122
           ++S   + +S ++    ++       S   + +  SDSS  D +    +     S   + 
Sbjct: 596 SDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSD 655

Query: 123 KGKNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENEL 182
              + +  N     +  +   +     + N SD S+SSDS NS++    +SS+    +  
Sbjct: 656 SSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSES--SDSSDSSDSDSS 713

Query: 183 KNKNTSKINGEEGKPHNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQEDMI 242
            + ++S  N  +    N+  + + +  NS    D        + ++   S ++    D  
Sbjct: 714 DSSDSSNSNSSDSDSSNSSDSSDSS--NSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 771

Query: 243 IHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLEKV 302
             S    + +  +SND      + D +++ +        S   +     D +N ++    
Sbjct: 772 DSSDSSDSSNSSDSNDSSNSSDSSDSSNSSD--SSNSSDSSDSSDSSDSDSSNSSDSSNS 829

Query: 303 AQENSSTFGLQTLQKMD---------PNVSDSKHSIANAKFLETAKKDSDQSWVSDVVK- 352
           +  + S+    +    D          N SDS +S +++     +   SD S  SD  + 
Sbjct: 830 SDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS-SDSSDSSDSSNSSDSSDSSDSNES 888

Query: 353 ---VDLTQSSVTNASSGNDHLNMEKEKYVSYISPLSAVSVMEDKLH----KRSPPPETIK 405
               D + SS ++ S  +D  N       S  S  S  S   D  +      S       
Sbjct: 889 SNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSS 948

Query: 406 SKLNTSVDTHKIKSSPSPEVVKPKITHSPDSVKSKATYVNSQAT 449
              N+S  ++   SS S +      + S DS  S  +  +S ++
Sbjct: 949 DSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 51/321 (15%), Positives = 119/321 (37%), Gaps = 15/321 (4%)

Query: 45   SRANQNVNAVHSHYTRAQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPD 104
            S ++ + N+  S  +   +NS   + +S ++    +++      S   N    SDSS   
Sbjct: 744  SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDS--SNSSDSSDSSNSS 801

Query: 105  EEKMKEEKYDYISRGENPKGKNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSEN 164
            +     +  D     ++    +    N     +            + + SD S+ SDS++
Sbjct: 802  DSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS------DSSDSSDSSDGSDSDS 855

Query: 165  SNKRIIDNSSEQKPENELKNKNTSKINGEEGKPHNNEKAGEETLKNSQPPWDQIQEDKKH 224
            SN+    NSS+    ++  N + S  + +  +  N+  + + +  +     D        
Sbjct: 856  SNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDS---DSSDSSNSS 912

Query: 225  EEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVSRP 284
            + ++   S D+    +   +S+   + +  +S+D      + D +++ +        S  
Sbjct: 913  DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD--SSNSSDSSD 970

Query: 285  PTPKCVIDITNDTNLEKVAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQ 344
                   D +N ++    +  + S+    +    D + S      +N+     +   S+ 
Sbjct: 971  SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNS 1030

Query: 345  SWVSDVVKVDLTQSSVTNASS 365
            S  SD    D + SS ++ SS
Sbjct: 1031 SDSSD--SSDSSDSSDSSDSS 1049



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 50/285 (17%), Positives = 98/285 (34%), Gaps = 14/285 (4%)

Query: 93   NKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLM------NKRRKPEEDEKKLNMK 146
            N    SDSS  +E     +  D  +  ++    + +        N     E      N  
Sbjct: 875  NSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSN 934

Query: 147  RLRTDNVSDFSESSDS----ENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKPHNNEK 202
               + N SD S+SSDS    ++SN     NSS+    N   + ++S  +       +++ 
Sbjct: 935  SSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDS 994

Query: 203  AGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLPQ 262
            +      NS    D          ++   S D+    D    S    +    +S+D    
Sbjct: 995  SDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1054

Query: 263  ECNMDKTHTMELLPKEKFVSRPPTPKC--VIDITNDTNLEKVAQENSSTFGLQTLQKMDP 320
              + D + + +            +       D ++ +N    +  + S+    +    D 
Sbjct: 1055 SNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1114

Query: 321  NVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSVTNASS 365
            + S    + +++     +   SD S  SD    D ++SS ++ SS
Sbjct: 1115 SDSSDSSNSSDSSDSSDSSDSSDSSNSSD--SSDSSESSDSSDSS 1157



 Score = 38.5 bits (88), Expect = 0.077
 Identities = 57/307 (18%), Positives = 114/307 (37%), Gaps = 28/307 (9%)

Query: 139 DEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGK-- 196
           D    + K ++ D+ +   ES+ ++++N    +NSS +   +   +++    NG + K  
Sbjct: 451 DSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGA 510

Query: 197 -PHNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHN 255
              +++   +    +S    +   +D    ++ K KS  +        +SS+ S  SD +
Sbjct: 511 EDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSD 570

Query: 256 SNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLEKVAQENSSTFGLQTL 315
           S+D      + D + +                    D ++ ++ +     NSS     + 
Sbjct: 571 SSD-SNSSSDSDSSDS--------------------DSSDSSDSDSSDSSNSSDSSDSSD 609

Query: 316 QKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSVTNASSGNDHLNMEKE 375
                + SDS  S +++   E+   DSD    S     D   S  ++ S  +D  N    
Sbjct: 610 SSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSS----DSNSSDSSDNSDSSDSSNSSNS 665

Query: 376 KYVSYISPLSAVSVMEDKLHKRSPPPETIKSKLNTSVDTHKIKSSPSPEVVKPKITHSPD 435
              S  S  S  S   D  +       +  S  + S D+     S S +      ++S D
Sbjct: 666 SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD 725

Query: 436 SVKSKAT 442
           S  S ++
Sbjct: 726 SDSSNSS 732



 Score = 38.1 bits (87), Expect = 0.10
 Identities = 66/385 (17%), Positives = 137/385 (35%), Gaps = 25/385 (6%)

Query: 71  NSQAAVPKQNTHQQQQQRSIRPNKRK----GSDS--SIPDEEKMKEEKYDYISRGENPKG 124
           N  A     N    +   S   ++ K    GSDS  +  D+     +  +  S G    G
Sbjct: 474 NDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNG 533

Query: 125 KNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKN 184
            + +  +   K + D    +       + S  S  SDS +SN     +SS+    +   +
Sbjct: 534 NDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDS 593

Query: 185 KNTSKINGEEGKPHNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQEDMIIH 244
            ++   N  +    ++     ++  +S    D  + +    +++ +         D   +
Sbjct: 594 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDN 653

Query: 245 SSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLEKVAQ 304
           S    + +  NS+D      + D + + +        S   +       +++++    + 
Sbjct: 654 SDSSDSSNSSNSSDSSDSSDSSDSSSSSD--------SSNSSDSSDSSDSSNSSESSDSS 705

Query: 305 ENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSVTNAS 364
           ++S +    +    + N SDS  S  N+     +   SD S  SD        S+ +++S
Sbjct: 706 DSSDSDSSDSSDSSNSNSSDSDSS--NSSDSSDSSNSSDSSDSSD-------SSNSSDSS 756

Query: 365 SGNDHLNMEKEKYVSYISPLSAVSVMEDKLHKRSPPPETIKSKLNTSVDTHKIKSSPSPE 424
             +D  N       S  S  S  S   D     +    +  S  N+S  ++   SS S +
Sbjct: 757 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSS--NSSDSSNSSDSSDSSD 814

Query: 425 VVKPKITHSPDSVKSKATYVNSQAT 449
                 ++S DS  S  +  +S ++
Sbjct: 815 SSDSDSSNSSDSSNSSDSSDSSNSS 839



 Score = 37.0 bits (84), Expect = 0.22
 Identities = 63/354 (17%), Positives = 126/354 (35%), Gaps = 10/354 (2%)

Query: 98  SDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKPEEDEKKLNMKRLRTD-NVSDF 156
           SDS   D     +      S   +    +    +   K E D    + K   +D N SD 
Sbjct: 591 SDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDS 650

Query: 157 SESSDS-ENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKPHNNEKAGEETLKNSQPPW 215
           S++SDS ++SN     +SS+    ++  + + S  + +     ++  + E +  +S    
Sbjct: 651 SDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESS--DSSDSS 708

Query: 216 DQIQEDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELL 275
           D    D            D+    D    S+   +    +S++      + D +++ +  
Sbjct: 709 DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSD-- 766

Query: 276 PKEKFVSRPPTPKCVIDITNDTNLEKVAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFL 335
             +   S   +       +ND++    + ++S++           +   S    +N+   
Sbjct: 767 SSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDS 826

Query: 336 ETAKKDSDQSWVSDVVKVDLTQSSVTNASSGNDHLNMEKEKYVSYISPLSAVSVMEDKLH 395
             +   SD S  SD    D + SS  + S  ++  +       S  S  S  S   D   
Sbjct: 827 SNSSDSSDSSNSSD--SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD 884

Query: 396 KRSPPPETIKSKLNTSVDTHKIKSSPSPEVVKPKITHSPDSVKSKATYVNSQAT 449
                  +  S  + S D+    SS S +      ++S DS +S  +  NS ++
Sbjct: 885 SNESSNSSDSSDSSNSSDSDSSDSSNSSD--SSDSSNSSDSSESSNSSDNSNSS 936



 Score = 36.6 bits (83), Expect = 0.29
 Identities = 62/371 (16%), Positives = 130/371 (35%), Gaps = 9/371 (2%)

Query: 56  SHYTRAQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDY 115
           S  ++++++S      S ++    +        S   N    SDSS   +        D 
Sbjct: 624 SDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSD- 682

Query: 116 ISRGENPKGKNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSEN-SNKRIIDNSS 174
            S   +    +    N     +  +   +     +D+ +  S  SDS N S+     NSS
Sbjct: 683 -SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSS 741

Query: 175 EQKPENELKNKNTSKINGEEGKPHNNEKAGEET-LKNSQPPWDQIQEDKKHEEAEKRKSV 233
           +    ++  N + S  + +     ++  + + +   +S    D        + ++   S 
Sbjct: 742 DSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSS 801

Query: 234 DTQLQEDMIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDI 293
           D+    D    SS+ S     NS+D      + D +++ +    +   S   +     + 
Sbjct: 802 DSSNSSDS-SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSD--SSDSSDSSDGSDSDSSNR 858

Query: 294 TNDTNLEKVAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKV 353
           ++ +N    +  + S+    +    D N  +S +S  ++    ++  DS  S  S     
Sbjct: 859 SDSSNSSDSSDSSDSSNSSDSSDSSDSN--ESSNSSDSSDSSNSSDSDSSDSSNSSDSSD 916

Query: 354 DLTQSSVTNASSGNDHLNMEKEKYVSYISPLSAVSVMEDKLHKRSPPPETIKSKLNTSVD 413
               S  + +S+ +D+ N       S  S  S  S   D  +       +  S  N+S  
Sbjct: 917 SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDS 976

Query: 414 THKIKSSPSPE 424
           +    SS S +
Sbjct: 977 SDSSNSSDSSD 987



 Score = 33.5 bits (75), Expect = 2.5
 Identities = 38/218 (17%), Positives = 77/218 (35%), Gaps = 15/218 (6%)

Query: 154  SDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKPHNNEKAGEETLKNSQP 213
            SD SESSDS +S+    D+S      +   + ++S  +      ++++ +      +S  
Sbjct: 1079 SDSSESSDSSDSSNS-SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1137

Query: 214  PWDQIQEDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLPQECNMDKTHTME 273
              +        E ++   S D+    D    S    +    NS+D      + D + + +
Sbjct: 1138 SSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1197

Query: 274  LLPKEKFVSRPPTPKCVIDITNDTNLEKVAQENSSTFGLQTLQKMDPNVSDSKHSIANAK 333
                              D ++ ++    +  + S+    +    D N S      +++ 
Sbjct: 1198 SSDSS-------------DSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSS 1244

Query: 334  FLETAKKDSDQSWVSDVVKVDLTQSSVTNASSGNDHLN 371
                +   SD S  SD    D    S + + SGN + N
Sbjct: 1245 DSSNSSDSSDSSDSSDSTS-DSNDESDSQSKSGNGNNN 1281


>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
          Length = 1758

 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 78/386 (20%), Positives = 142/386 (36%), Gaps = 25/386 (6%)

Query: 72   SQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMN 131
            + A+  K  T  +      + N  K  +S+ P+    KE   D ++   N K  ++    
Sbjct: 1360 NSASSEKGKTKDRDYSVLEKENPEKRKNSTQPE----KESNLDRLNEQGNFKSLSQSSKE 1415

Query: 132  KRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKIN 191
             R   + D  + +  +  T N    ++    E S+ +  D  +E     +  ++N    +
Sbjct: 1416 ARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSAS 1475

Query: 192  GEEGKPHN-----NEKAGEETLKNSQPPWDQIQEDKKHEEAEKR-----KSVDTQLQEDM 241
            G++ KP        +  G+    NS P  D+   D K     KR     KSVD    +D 
Sbjct: 1476 GQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDR 1535

Query: 242  IIHSSEQSTVSDHNSNDLL----PQECNMDKTHTMELLPKEKFVSRPP---TPKCVIDIT 294
              H  E     + + N LL    P E  ++K      + K     +P    + +   D+T
Sbjct: 1536 EKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLT 1595

Query: 295  NDTNLEKVAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVD 354
             +T+      + + +     +   +   S +       K +E AK+  D + V   V + 
Sbjct: 1596 RETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQ-VGIS 1654

Query: 355  LTQSSVTNASSGNDHLNMEKEKYVSYISPLSAVSVMEDKLHKRSPPPETIKSKLNTSVDT 414
              QS  + + S +   +    +  S+ S  S+    + K  K+    E  K K +     
Sbjct: 1655 RNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSK--KKKKKKEKKKHKKHKKHKK 1712

Query: 415  HKIKSSPSPEVVKPKITHSPDSVKSK 440
            HK  +    E+ K +  H     KSK
Sbjct: 1713 HKKHAGTEVELEKSQ-KHKHKKKKSK 1737



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 114/499 (22%), Positives = 182/499 (36%), Gaps = 55/499 (11%)

Query: 986  RAPVFHPPIHHSLE---RKEGSYSSLSPP-----TLTPVMPVNAGGKVQESQKPPTLIPE 1037
            R+P   PPI  + E   + + + SS S       T TP    +   K  +  KP      
Sbjct: 1017 RSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKV 1076

Query: 1038 PKDSQANFKSSSEQSLTEMWRPNNNLSK----------EKTEWH-----VEKSSGKLQAA 1082
             KD   + KS    +  E  +  N  +K           KTE        E SS K+   
Sbjct: 1077 KKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKL 1136

Query: 1083 MASVIVRPSSSTKT--DSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNV 1140
              + IV+PS   K   D+    +   KD++S   SA A K   +KL    ETG+ I    
Sbjct: 1137 EVTEIVKPSPKRKMEPDTEKMDRTPEKDKIS--LSAPAKK---IKLNR--ETGKKIGSTE 1189

Query: 1141 NSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISS 1200
            N  +    SEK  ++ S       V   V           ++  D TS SS GGS V  S
Sbjct: 1190 NISNTKEPSEK-LESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKS 1248

Query: 1201 LSNTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDF 1260
               T    T  + +   + +   A  ++  +    P +                  T   
Sbjct: 1249 EEKTDTKRTVIKTMEEYN-NDNTAPAEDVIIMIQVPQSKWDKD--DFESEEEDVKSTQPI 1305

Query: 1261 IHLKKHKAALAAAQYKSSNA-----SETEPNA-IKNQTLSASLPLDSTVICSTINKANSV 1314
              + K  + +     K SN       E+EP+  I+  T   S  +    + S+ N A+S 
Sbjct: 1306 SSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASS- 1364

Query: 1315 GNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSD 1374
               +  +T   +Y    K+     + E+ KN+ + E   N +  + +  +   ++ +S +
Sbjct: 1365 ---EKGKTKDRDYSVLEKE-----NPEKRKNSTQPEKESN-LDRLNEQGNFKSLSQSSKE 1415

Query: 1375 IQNSVDSKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKK 1434
             + S           KD   NR K K  Y++   S  S +   +  + T+R+  P+  K 
Sbjct: 1416 ARTSDKHDSTRASSNKDFTPNRDK-KTDYDTREYS--SSKRRDEKNELTRRKDSPSRNKD 1472

Query: 1435 QNDLQKRKGEIEEDLKPNG 1453
                QK K   E DL   G
Sbjct: 1473 SASGQKNKPREERDLPKKG 1491



 Score = 38.5 bits (88), Expect = 0.077
 Identities = 84/426 (19%), Positives = 138/426 (32%), Gaps = 94/426 (22%)

Query: 81   THQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKPEEDE 140
            +H+ +   S  P K    D     +    +EK    + G+    K+K    KRRK EE E
Sbjct: 854  SHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKK-HRKRRKGEESE 912

Query: 141  KKLNMKRLRT-----------DNVSDF--------------SESSDSE------------ 163
              LN + L T           +N +D                E  D+E            
Sbjct: 913  GFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDK 972

Query: 164  ----------NSNKRIIDNSSEQKPENELKNKN--TSKINGEEGKPHNNE----KAGEET 207
                      +  KR  D S+  K EN +K       K++GE  +   +E    KA EET
Sbjct: 973  RERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEET 1032

Query: 208  LKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLPQECNMD 267
             K          +  +      RK+     +E       ++  V    S D+  +     
Sbjct: 1033 PKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSE----- 1087

Query: 268  KTHTMELLPKEKFVSRPPTPKCVIDITNDTNLEKVAQENSSTFGLQTLQKMDPNVSDSKH 327
                 +L  KE+   +P      +D   +    K  ++            +D +   S  
Sbjct: 1088 -----KLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKG-----------VDKDFESSSM 1131

Query: 328  SIANAKFLETAKKDSDQSWVSDVVKVDLTQSS---VTNASSGNDHLNMEKEKYVSYISPL 384
             I+  +  E  K    +    D  K+D T        +A +    LN E  K +     +
Sbjct: 1132 KISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENI 1191

Query: 385  SAVSVMEDKLHKRSPPPETIKSKLNTSVDTHKIKSSPSPEVVKPKITHSPDSVKSKATYV 444
            S      +KL   S           + V   K+K       V+ K+T +  S  +   Y 
Sbjct: 1192 SNTKEPSEKLESTS-----------SKVKQEKVKGK-----VRRKVTGTEGSSSTLVDYT 1235

Query: 445  NSQATG 450
            ++ +TG
Sbjct: 1236 STSSTG 1241



 Score = 35.8 bits (81), Expect = 0.50
 Identities = 28/151 (18%), Positives = 61/151 (40%), Gaps = 1/151 (0%)

Query: 1339 HSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRK 1398
            ++E D  +N       S   I K     ++      +  +   ++ + +       +   
Sbjct: 1607 YNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSP 1666

Query: 1399 AKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSRS 1458
            ++    SGS++     S S +E +  ++ K   +KK++   K+  + ++       L +S
Sbjct: 1667 SRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKS 1726

Query: 1459 AKERSKLKLQSNSNTGIPRSVLKDWRKVKKL 1489
             K + K K +S  N    +   KD +KVK +
Sbjct: 1727 QKHKHK-KKKSKKNKDKEKEKEKDDQKVKSV 1756



 Score = 32.0 bits (71), Expect = 7.2
 Identities = 39/180 (21%), Positives = 74/180 (41%), Gaps = 17/180 (9%)

Query: 66   PRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGK 125
            P+P ++  + +    T +  +           S+S++     +KEE+    S G   K  
Sbjct: 1580 PKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNV----SVKEEE----SSGNISKDL 1631

Query: 126  NKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSES---SDSENSNKRIIDNSSEQKPENEL 182
               ++ K ++  +    + +   R  + S  S S   S S + ++    +SS    E++ 
Sbjct: 1632 KDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQD 1691

Query: 183  KNKNTSKINGEEGKPHNNEK-----AGEET-LKNSQPPWDQIQEDKKHEEAEKRKSVDTQ 236
              K   K   ++ K H   K     AG E  L+ SQ    + ++ KK+++ EK K  D Q
Sbjct: 1692 SKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQ 1751



 Score = 32.0 bits (71), Expect = 7.2
 Identities = 25/112 (22%), Positives = 56/112 (50%), Gaps = 14/112 (12%)

Query: 37   IGITSRRRSRANQNVNAVHSH-----YTRAQANSPRPAMNSQAAVPKQNTHQQQQQRSIR 91
            +GI SR +S ++ +V+   SH      TR+ ++S   A +  +   K+   +++ ++  +
Sbjct: 1651 VGI-SRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKK 1709

Query: 92   PNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKPEEDEKKL 143
              K K    +  + EK ++ K+         K K+K   +K ++ E+D++K+
Sbjct: 1710 HKKHKKHAGTEVELEKSQKHKHK--------KKKSKKNKDKEKEKEKDDQKV 1753


>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
          Length = 1792

 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 78/386 (20%), Positives = 142/386 (36%), Gaps = 25/386 (6%)

Query: 72   SQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMN 131
            + A+  K  T  +      + N  K  +S+ P+    KE   D ++   N K  ++    
Sbjct: 1394 NSASSEKGKTKDRDYSVLEKENPEKRKNSTQPE----KESNLDRLNEQGNFKSLSQSSKE 1449

Query: 132  KRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKIN 191
             R   + D  + +  +  T N    ++    E S+ +  D  +E     +  ++N    +
Sbjct: 1450 ARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSAS 1509

Query: 192  GEEGKPHN-----NEKAGEETLKNSQPPWDQIQEDKKHEEAEKR-----KSVDTQLQEDM 241
            G++ KP        +  G+    NS P  D+   D K     KR     KSVD    +D 
Sbjct: 1510 GQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDR 1569

Query: 242  IIHSSEQSTVSDHNSNDLL----PQECNMDKTHTMELLPKEKFVSRPP---TPKCVIDIT 294
              H  E     + + N LL    P E  ++K      + K     +P    + +   D+T
Sbjct: 1570 EKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLT 1629

Query: 295  NDTNLEKVAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVD 354
             +T+      + + +     +   +   S +       K +E AK+  D + V   V + 
Sbjct: 1630 RETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQ-VGIS 1688

Query: 355  LTQSSVTNASSGNDHLNMEKEKYVSYISPLSAVSVMEDKLHKRSPPPETIKSKLNTSVDT 414
              QS  + + S +   +    +  S+ S  S+    + K  K+    E  K K +     
Sbjct: 1689 RNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSK--KKKKKKEKKKHKKHKKHKK 1746

Query: 415  HKIKSSPSPEVVKPKITHSPDSVKSK 440
            HK  +    E+ K +  H     KSK
Sbjct: 1747 HKKHAGTEVELEKSQ-KHKHKKKKSK 1771



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 114/499 (22%), Positives = 182/499 (36%), Gaps = 55/499 (11%)

Query: 986  RAPVFHPPIHHSLE---RKEGSYSSLSPP-----TLTPVMPVNAGGKVQESQKPPTLIPE 1037
            R+P   PPI  + E   + + + SS S       T TP    +   K  +  KP      
Sbjct: 1051 RSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKV 1110

Query: 1038 PKDSQANFKSSSEQSLTEMWRPNNNLSK----------EKTEWH-----VEKSSGKLQAA 1082
             KD   + KS    +  E  +  N  +K           KTE        E SS K+   
Sbjct: 1111 KKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKL 1170

Query: 1083 MASVIVRPSSSTKT--DSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNV 1140
              + IV+PS   K   D+    +   KD++S   SA A K   +KL    ETG+ I    
Sbjct: 1171 EVTEIVKPSPKRKMEPDTEKMDRTPEKDKIS--LSAPAKK---IKLNR--ETGKKIGSTE 1223

Query: 1141 NSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISS 1200
            N  +    SEK  ++ S       V   V           ++  D TS SS GGS V  S
Sbjct: 1224 NISNTKEPSEK-LESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKS 1282

Query: 1201 LSNTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDF 1260
               T    T  + +   + +   A  ++  +    P +                  T   
Sbjct: 1283 EEKTDTKRTVIKTMEEYN-NDNTAPAEDVIIMIQVPQSKWDKD--DFESEEEDVKSTQPI 1339

Query: 1261 IHLKKHKAALAAAQYKSSNA-----SETEPNA-IKNQTLSASLPLDSTVICSTINKANSV 1314
              + K  + +     K SN       E+EP+  I+  T   S  +    + S+ N A+S 
Sbjct: 1340 SSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASS- 1398

Query: 1315 GNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSD 1374
               +  +T   +Y    K+     + E+ KN+ + E   N +  + +  +   ++ +S +
Sbjct: 1399 ---EKGKTKDRDYSVLEKE-----NPEKRKNSTQPEKESN-LDRLNEQGNFKSLSQSSKE 1449

Query: 1375 IQNSVDSKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKK 1434
             + S           KD   NR K K  Y++   S  S +   +  + T+R+  P+  K 
Sbjct: 1450 ARTSDKHDSTRASSNKDFTPNRDK-KTDYDTREYS--SSKRRDEKNELTRRKDSPSRNKD 1506

Query: 1435 QNDLQKRKGEIEEDLKPNG 1453
                QK K   E DL   G
Sbjct: 1507 SASGQKNKPREERDLPKKG 1525



 Score = 38.5 bits (88), Expect = 0.077
 Identities = 84/426 (19%), Positives = 138/426 (32%), Gaps = 94/426 (22%)

Query: 81   THQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKPEEDE 140
            +H+ +   S  P K    D     +    +EK    + G+    K+K    KRRK EE E
Sbjct: 888  SHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKK-HRKRRKGEESE 946

Query: 141  KKLNMKRLRT-----------DNVSDF--------------SESSDSE------------ 163
              LN + L T           +N +D                E  D+E            
Sbjct: 947  GFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDK 1006

Query: 164  ----------NSNKRIIDNSSEQKPENELKNKN--TSKINGEEGKPHNNE----KAGEET 207
                      +  KR  D S+  K EN +K       K++GE  +   +E    KA EET
Sbjct: 1007 RERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEET 1066

Query: 208  LKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLPQECNMD 267
             K          +  +      RK+     +E       ++  V    S D+  +     
Sbjct: 1067 PKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSE----- 1121

Query: 268  KTHTMELLPKEKFVSRPPTPKCVIDITNDTNLEKVAQENSSTFGLQTLQKMDPNVSDSKH 327
                 +L  KE+   +P      +D   +    K  ++            +D +   S  
Sbjct: 1122 -----KLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKG-----------VDKDFESSSM 1165

Query: 328  SIANAKFLETAKKDSDQSWVSDVVKVDLTQSS---VTNASSGNDHLNMEKEKYVSYISPL 384
             I+  +  E  K    +    D  K+D T        +A +    LN E  K +     +
Sbjct: 1166 KISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENI 1225

Query: 385  SAVSVMEDKLHKRSPPPETIKSKLNTSVDTHKIKSSPSPEVVKPKITHSPDSVKSKATYV 444
            S      +KL   S           + V   K+K       V+ K+T +  S  +   Y 
Sbjct: 1226 SNTKEPSEKLESTS-----------SKVKQEKVKGK-----VRRKVTGTEGSSSTLVDYT 1269

Query: 445  NSQATG 450
            ++ +TG
Sbjct: 1270 STSSTG 1275



 Score = 35.8 bits (81), Expect = 0.50
 Identities = 28/151 (18%), Positives = 61/151 (40%), Gaps = 1/151 (0%)

Query: 1339 HSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRK 1398
            ++E D  +N       S   I K     ++      +  +   ++ + +       +   
Sbjct: 1641 YNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSP 1700

Query: 1399 AKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSRS 1458
            ++    SGS++     S S +E +  ++ K   +KK++   K+  + ++       L +S
Sbjct: 1701 SRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKS 1760

Query: 1459 AKERSKLKLQSNSNTGIPRSVLKDWRKVKKL 1489
             K + K K +S  N    +   KD +KVK +
Sbjct: 1761 QKHKHK-KKKSKKNKDKEKEKEKDDQKVKSV 1790



 Score = 32.0 bits (71), Expect = 7.2
 Identities = 39/180 (21%), Positives = 74/180 (41%), Gaps = 17/180 (9%)

Query: 66   PRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGK 125
            P+P ++  + +    T +  +           S+S++     +KEE+    S G   K  
Sbjct: 1614 PKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNV----SVKEEE----SSGNISKDL 1665

Query: 126  NKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSES---SDSENSNKRIIDNSSEQKPENEL 182
               ++ K ++  +    + +   R  + S  S S   S S + ++    +SS    E++ 
Sbjct: 1666 KDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQD 1725

Query: 183  KNKNTSKINGEEGKPHNNEK-----AGEET-LKNSQPPWDQIQEDKKHEEAEKRKSVDTQ 236
              K   K   ++ K H   K     AG E  L+ SQ    + ++ KK+++ EK K  D Q
Sbjct: 1726 SKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQ 1785



 Score = 32.0 bits (71), Expect = 7.2
 Identities = 25/112 (22%), Positives = 56/112 (50%), Gaps = 14/112 (12%)

Query: 37   IGITSRRRSRANQNVNAVHSH-----YTRAQANSPRPAMNSQAAVPKQNTHQQQQQRSIR 91
            +GI SR +S ++ +V+   SH      TR+ ++S   A +  +   K+   +++ ++  +
Sbjct: 1685 VGI-SRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKK 1743

Query: 92   PNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKPEEDEKKL 143
              K K    +  + EK ++ K+         K K+K   +K ++ E+D++K+
Sbjct: 1744 HKKHKKHAGTEVELEKSQKHKHK--------KKKSKKNKDKEKEKEKDDQKV 1787


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 91/501 (18%), Positives = 183/501 (36%), Gaps = 25/501 (4%)

Query: 876  TTLSNSVVNEPPR-SYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQ 934
            TT+++++ +E  + S  S +++ ++ +     +A+  A+  T  S   S + P      +
Sbjct: 782  TTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSE 841

Query: 935  PESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPI 994
              +                S + T       + T  T+ S  T  S              
Sbjct: 842  TTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTT----- 896

Query: 995  HHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLT 1054
              S E  E + +S     +T V    +      ++   T     + S+    S++  S T
Sbjct: 897  --STEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-SET 953

Query: 1055 EMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRV-SER 1113
                   + +   T    E ++     +  + +    S T T S+   +  +     SE 
Sbjct: 954  ITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSET 1013

Query: 1114 SSAGAHKTDC-LKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTM 1172
            ++     T+  +   E  ET  +      + +V+T   +     ++GS  ++    V+T 
Sbjct: 1014 TTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTT----VSTT 1069

Query: 1173 CNTKTDVITSAADTTSVSSWGGSEVISSLSNTILASTSSECVSSKSVSQPVAQKQECKVS 1232
             +  T   T+  +TT+VS+ G     +S + +   +T+     SK+ +      +   VS
Sbjct: 1070 GSETTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1233 TTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQT 1292
            TT+  T  +S TGS +         T  +     +A  ++A    +  + TE     ++T
Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE----GSET 1183

Query: 1293 LSASLPLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENS 1352
             +AS     T   ST     +  +   S+T+  +          T  SE    T+   ++
Sbjct: 1184 TTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSE----TSTPSSA 1239

Query: 1353 GNSVSEIIKPCSVNLIASTSS 1373
            G+  +      S   IAST+S
Sbjct: 1240 GSETNTAFIIGSETTIASTAS 1260



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 72/355 (20%), Positives = 137/355 (38%), Gaps = 33/355 (9%)

Query: 1091 SSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSE 1150
            ++ + T S   +   S   ++  S+AG+  T    ++ AG +G        S++  + + 
Sbjct: 46   TTPSPTGSQTTIVSISGSEITTTSTAGSENTT---VSSAG-SGTTTASMAGSETTVSTAG 101

Query: 1151 KNFQAVSQGSVPSSVMSAV------NTMCNTKTDVITSAADTTSVSSWGGSEVISSLS-- 1202
                 VS     ++++SA+      N+  +++T V ++A   T+  S  GSE  ++ +  
Sbjct: 102  SETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTAD 161

Query: 1203 --NTILASTSSECVS-----SKSVSQPVAQKQECKVSTTAPVTLASSKTGSV-VQPSSGF 1254
               T  ++T SE  +     S++++   A  +   VST    T   S TGS     S+  
Sbjct: 162  SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 1255 SGTT--DFIHLKKHKAALAAAQYKSSNA-SETEPNAIKNQTLSASLPLDSTVICSTINKA 1311
            S TT    +  +  K + A ++   S A SET   + ++   + +   DS    +T    
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK---TTTAST 278

Query: 1312 NSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSV-------SEIIKPCS 1364
                   AS T           +  T  S     T K+  + + V       SE I+  +
Sbjct: 279  TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338

Query: 1365 VNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKS 1419
            V    +T S   +   +  I+      D     +       GSE+  +    S++
Sbjct: 339  VGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 50/261 (19%), Positives = 96/261 (36%), Gaps = 15/261 (5%)

Query: 1128 EAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSA------VNTMCNTKTDVIT 1181
            E  ET  +        +V T+  +N    + GS  ++V +        +T  +  T V T
Sbjct: 509  EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVST 568

Query: 1182 SAADTTSVSSWGGSEVISSLSN----TILASTSSECVSSKSVSQPVAQKQECKVSTTAPV 1237
            + A+TT+ S+ G     +S +     T+  + S    +S + S+  +       +TTA  
Sbjct: 569  TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAST 628

Query: 1238 TLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASL 1297
            T + + T S     +    TTD                 +  +  T  +A  ++T  ++ 
Sbjct: 629  TSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTE 688

Query: 1298 PLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWL-----TRHSEEDKNTNKMENS 1352
               +T +  T ++   V    +  T+     +++  A +     T  S E   T      
Sbjct: 689  GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 748

Query: 1353 GNSVSEIIKPCSVNLIASTSS 1373
            G+  +      S    AST+S
Sbjct: 749  GSETTSASTTGSETTTASTTS 769



 Score = 32.3 bits (72), Expect = 5.5
 Identities = 35/172 (20%), Positives = 65/172 (37%), Gaps = 19/172 (11%)

Query: 1083 MASVIVRPSSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNS 1142
            M +V    S +T   ++ +    S    SE ++     ++    + AG           +
Sbjct: 1143 MTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSE------TTTA 1196

Query: 1143 DSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISSLS 1202
             +  +++     A S+ +  S+  S  NT C T ++        TS  S  GSE     +
Sbjct: 1197 STAGSETTTASTAGSETTTASTSGSETNTACTTGSE--------TSTPSSAGSE-----T 1243

Query: 1203 NTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGF 1254
            NT     S   ++S +  +P A       +TT  +T + +   S    S+ F
Sbjct: 1244 NTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTF 1295


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 101/554 (18%), Positives = 208/554 (37%), Gaps = 27/554 (4%)

Query: 876  TTLSNSVVNEPPR-SYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQ 934
            TT+++++ +E  + S  S +++ ++ +     +A+  A+  T  S   S + P      +
Sbjct: 782  TTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSE 841

Query: 935  PESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPI 994
              +                S + T       + T  T+ S  T  S              
Sbjct: 842  TTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTT----- 896

Query: 995  HHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLT 1054
              S E  E + +S     +T V    +      ++   T     + S+    S++  S T
Sbjct: 897  --STEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-SET 953

Query: 1055 EMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRV-SER 1113
                   + +   T    E ++     +  + +    S T T S+   +  +     SE 
Sbjct: 954  ITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSET 1013

Query: 1114 SSAGAHKTDC-LKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTM 1172
            ++     T+  +   E  ET  +      + +V+T   +     ++GS  ++    V+T 
Sbjct: 1014 TTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTT----VSTT 1069

Query: 1173 CNTKTDVITSAADTTSVSSWGGSEVISSLSNTILASTSSECVSSKSVSQPVAQKQECKVS 1232
             +  T   T+  +TT+VS+ G     +S + +   +T+     SK+ +      +   VS
Sbjct: 1070 GSETTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1233 TTAPVTLASSKTGS-VVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNAS-----ETEPN 1286
            TT+  T  +S TGS +    +  S TT    +       +AA  +++  S      T  +
Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS 1187

Query: 1287 AIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQP-NYHTKLKKAWLTRHSEEDKN 1345
               ++T +AS     T   ST     +      S+TS P +  ++   A++        +
Sbjct: 1188 TAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAS 1247

Query: 1346 TNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKAKRTYES 1405
            T  +E +  S++   +  +V++ AS ++    +V S   V    K   V+ +    T  S
Sbjct: 1248 TASLEPTATSLTG-SETTTVSITASGATAASTTVSSTTFV--LTKATDVSIQPITNTPMS 1304

Query: 1406 GSESGDSDESESKS 1419
            G+ +  +  + S S
Sbjct: 1305 GTRTTGTRPTASSS 1318



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 72/355 (20%), Positives = 137/355 (38%), Gaps = 33/355 (9%)

Query: 1091 SSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSE 1150
            ++ + T S   +   S   ++  S+AG+  T    ++ AG +G        S++  + + 
Sbjct: 46   TTPSPTGSQTTIVSISGSEITTTSTAGSENTT---VSSAG-SGTTTASMAGSETTVSTAG 101

Query: 1151 KNFQAVSQGSVPSSVMSAV------NTMCNTKTDVITSAADTTSVSSWGGSEVISSLS-- 1202
                 VS     ++++SA+      N+  +++T V ++A   T+  S  GSE  ++ +  
Sbjct: 102  SETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTAD 161

Query: 1203 --NTILASTSSECVS-----SKSVSQPVAQKQECKVSTTAPVTLASSKTGSV-VQPSSGF 1254
               T  ++T SE  +     S++++   A  +   VST    T   S TGS     S+  
Sbjct: 162  SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 1255 SGTT--DFIHLKKHKAALAAAQYKSSNA-SETEPNAIKNQTLSASLPLDSTVICSTINKA 1311
            S TT    +  +  K + A ++   S A SET   + ++   + +   DS    +T    
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK---TTTAST 278

Query: 1312 NSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSV-------SEIIKPCS 1364
                   AS T           +  T  S     T K+  + + V       SE I+  +
Sbjct: 279  TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338

Query: 1365 VNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKS 1419
            V    +T S   +   +  I+      D     +       GSE+  +    S++
Sbjct: 339  VGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 50/261 (19%), Positives = 96/261 (36%), Gaps = 15/261 (5%)

Query: 1128 EAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSA------VNTMCNTKTDVIT 1181
            E  ET  +        +V T+  +N    + GS  ++V +        +T  +  T V T
Sbjct: 509  EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVST 568

Query: 1182 SAADTTSVSSWGGSEVISSLSN----TILASTSSECVSSKSVSQPVAQKQECKVSTTAPV 1237
            + A+TT+ S+ G     +S +     T+  + S    +S + S+  +       +TTA  
Sbjct: 569  TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAST 628

Query: 1238 TLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASL 1297
            T + + T S     +    TTD                 +  +  T  +A  ++T  ++ 
Sbjct: 629  TSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTE 688

Query: 1298 PLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWL-----TRHSEEDKNTNKMENS 1352
               +T +  T ++   V    +  T+     +++  A +     T  S E   T      
Sbjct: 689  GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 748

Query: 1353 GNSVSEIIKPCSVNLIASTSS 1373
            G+  +      S    AST+S
Sbjct: 749  GSETTSASTTGSETTTASTTS 769


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 101/554 (18%), Positives = 208/554 (37%), Gaps = 27/554 (4%)

Query: 876  TTLSNSVVNEPPR-SYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQ 934
            TT+++++ +E  + S  S +++ ++ +     +A+  A+  T  S   S + P      +
Sbjct: 782  TTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSE 841

Query: 935  PESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPI 994
              +                S + T       + T  T+ S  T  S              
Sbjct: 842  TTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTT----- 896

Query: 995  HHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLT 1054
              S E  E + +S     +T V    +      ++   T     + S+    S++  S T
Sbjct: 897  --STEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-SET 953

Query: 1055 EMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRV-SER 1113
                   + +   T    E ++     +  + +    S T T S+   +  +     SE 
Sbjct: 954  ITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSET 1013

Query: 1114 SSAGAHKTDC-LKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTM 1172
            ++     T+  +   E  ET  +      + +V+T   +     ++GS  ++    V+T 
Sbjct: 1014 TTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTT----VSTT 1069

Query: 1173 CNTKTDVITSAADTTSVSSWGGSEVISSLSNTILASTSSECVSSKSVSQPVAQKQECKVS 1232
             +  T   T+  +TT+VS+ G     +S + +   +T+     SK+ +      +   VS
Sbjct: 1070 GSETTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1233 TTAPVTLASSKTGS-VVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNAS-----ETEPN 1286
            TT+  T  +S TGS +    +  S TT    +       +AA  +++  S      T  +
Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS 1187

Query: 1287 AIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQP-NYHTKLKKAWLTRHSEEDKN 1345
               ++T +AS     T   ST     +      S+TS P +  ++   A++        +
Sbjct: 1188 TAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAS 1247

Query: 1346 TNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKAKRTYES 1405
            T  +E +  S++   +  +V++ AS ++    +V S   V    K   V+ +    T  S
Sbjct: 1248 TASLEPTATSLTG-SETTTVSITASGATAASTTVSSTTFV--LTKATDVSIQPITNTPMS 1304

Query: 1406 GSESGDSDESESKS 1419
            G+ +  +  + S S
Sbjct: 1305 GTRTTGTRPTASSS 1318



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 72/355 (20%), Positives = 137/355 (38%), Gaps = 33/355 (9%)

Query: 1091 SSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSE 1150
            ++ + T S   +   S   ++  S+AG+  T    ++ AG +G        S++  + + 
Sbjct: 46   TTPSPTGSQTTIVSISGSEITTTSTAGSENTT---VSSAG-SGTTTASMAGSETTVSTAG 101

Query: 1151 KNFQAVSQGSVPSSVMSAV------NTMCNTKTDVITSAADTTSVSSWGGSEVISSLS-- 1202
                 VS     ++++SA+      N+  +++T V ++A   T+  S  GSE  ++ +  
Sbjct: 102  SETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTAD 161

Query: 1203 --NTILASTSSECVS-----SKSVSQPVAQKQECKVSTTAPVTLASSKTGSV-VQPSSGF 1254
               T  ++T SE  +     S++++   A  +   VST    T   S TGS     S+  
Sbjct: 162  SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 1255 SGTT--DFIHLKKHKAALAAAQYKSSNA-SETEPNAIKNQTLSASLPLDSTVICSTINKA 1311
            S TT    +  +  K + A ++   S A SET   + ++   + +   DS    +T    
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK---TTTAST 278

Query: 1312 NSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSV-------SEIIKPCS 1364
                   AS T           +  T  S     T K+  + + V       SE I+  +
Sbjct: 279  TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338

Query: 1365 VNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKS 1419
            V    +T S   +   +  I+      D     +       GSE+  +    S++
Sbjct: 339  VGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 50/261 (19%), Positives = 96/261 (36%), Gaps = 15/261 (5%)

Query: 1128 EAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSA------VNTMCNTKTDVIT 1181
            E  ET  +        +V T+  +N    + GS  ++V +        +T  +  T V T
Sbjct: 509  EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVST 568

Query: 1182 SAADTTSVSSWGGSEVISSLSN----TILASTSSECVSSKSVSQPVAQKQECKVSTTAPV 1237
            + A+TT+ S+ G     +S +     T+  + S    +S + S+  +       +TTA  
Sbjct: 569  TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAST 628

Query: 1238 TLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASL 1297
            T + + T S     +    TTD                 +  +  T  +A  ++T  ++ 
Sbjct: 629  TSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTE 688

Query: 1298 PLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWL-----TRHSEEDKNTNKMENS 1352
               +T +  T ++   V    +  T+     +++  A +     T  S E   T      
Sbjct: 689  GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 748

Query: 1353 GNSVSEIIKPCSVNLIASTSS 1373
            G+  +      S    AST+S
Sbjct: 749  GSETTSASTTGSETTTASTTS 769


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 91/501 (18%), Positives = 183/501 (36%), Gaps = 25/501 (4%)

Query: 876  TTLSNSVVNEPPR-SYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQ 934
            TT+++++ +E  + S  S +++ ++ +     +A+  A+  T  S   S + P      +
Sbjct: 782  TTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSE 841

Query: 935  PESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPI 994
              +                S + T       + T  T+ S  T  S              
Sbjct: 842  TTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTT----- 896

Query: 995  HHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLT 1054
              S E  E + +S     +T V    +      ++   T     + S+    S++  S T
Sbjct: 897  --STEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-SET 953

Query: 1055 EMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRV-SER 1113
                   + +   T    E ++     +  + +    S T T S+   +  +     SE 
Sbjct: 954  ITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSET 1013

Query: 1114 SSAGAHKTDC-LKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTM 1172
            ++     T+  +   E  ET  +      + +V+T   +     ++GS  ++    V+T 
Sbjct: 1014 TTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTT----VSTT 1069

Query: 1173 CNTKTDVITSAADTTSVSSWGGSEVISSLSNTILASTSSECVSSKSVSQPVAQKQECKVS 1232
             +  T   T+  +TT+VS+ G     +S + +   +T+     SK+ +      +   VS
Sbjct: 1070 GSETTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1233 TTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQT 1292
            TT+  T  +S TGS +         T  +     +A  ++A    +  + TE     ++T
Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE----GSET 1183

Query: 1293 LSASLPLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENS 1352
             +AS     T   ST     +  +   S+T+  +          T  SE    T+   ++
Sbjct: 1184 TTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSE----TSTPSSA 1239

Query: 1353 GNSVSEIIKPCSVNLIASTSS 1373
            G+  +      S   IAST+S
Sbjct: 1240 GSETNTAFIIGSETTIASTAS 1260



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 72/355 (20%), Positives = 137/355 (38%), Gaps = 33/355 (9%)

Query: 1091 SSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSE 1150
            ++ + T S   +   S   ++  S+AG+  T    ++ AG +G        S++  + + 
Sbjct: 46   TTPSPTGSQTTIVSISGSEITTTSTAGSENTT---VSSAG-SGTTTASMAGSETTVSTAG 101

Query: 1151 KNFQAVSQGSVPSSVMSAV------NTMCNTKTDVITSAADTTSVSSWGGSEVISSLS-- 1202
                 VS     ++++SA+      N+  +++T V ++A   T+  S  GSE  ++ +  
Sbjct: 102  SETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTAD 161

Query: 1203 --NTILASTSSECVS-----SKSVSQPVAQKQECKVSTTAPVTLASSKTGSV-VQPSSGF 1254
               T  ++T SE  +     S++++   A  +   VST    T   S TGS     S+  
Sbjct: 162  SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 1255 SGTT--DFIHLKKHKAALAAAQYKSSNA-SETEPNAIKNQTLSASLPLDSTVICSTINKA 1311
            S TT    +  +  K + A ++   S A SET   + ++   + +   DS    +T    
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK---TTTAST 278

Query: 1312 NSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSV-------SEIIKPCS 1364
                   AS T           +  T  S     T K+  + + V       SE I+  +
Sbjct: 279  TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338

Query: 1365 VNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKS 1419
            V    +T S   +   +  I+      D     +       GSE+  +    S++
Sbjct: 339  VGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 50/261 (19%), Positives = 96/261 (36%), Gaps = 15/261 (5%)

Query: 1128 EAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSA------VNTMCNTKTDVIT 1181
            E  ET  +        +V T+  +N    + GS  ++V +        +T  +  T V T
Sbjct: 509  EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVST 568

Query: 1182 SAADTTSVSSWGGSEVISSLSN----TILASTSSECVSSKSVSQPVAQKQECKVSTTAPV 1237
            + A+TT+ S+ G     +S +     T+  + S    +S + S+  +       +TTA  
Sbjct: 569  TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAST 628

Query: 1238 TLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASL 1297
            T + + T S     +    TTD                 +  +  T  +A  ++T  ++ 
Sbjct: 629  TSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTE 688

Query: 1298 PLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWL-----TRHSEEDKNTNKMENS 1352
               +T +  T ++   V    +  T+     +++  A +     T  S E   T      
Sbjct: 689  GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 748

Query: 1353 GNSVSEIIKPCSVNLIASTSS 1373
            G+  +      S    AST+S
Sbjct: 749  GSETTSASTTGSETTTASTTS 769



 Score = 32.3 bits (72), Expect = 5.5
 Identities = 35/172 (20%), Positives = 65/172 (37%), Gaps = 19/172 (11%)

Query: 1083 MASVIVRPSSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNS 1142
            M +V    S +T   ++ +    S    SE ++     ++    + AG           +
Sbjct: 1143 MTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSE------TTTA 1196

Query: 1143 DSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISSLS 1202
             +  +++     A S+ +  S+  S  NT C T ++        TS  S  GSE     +
Sbjct: 1197 STAGSETTTASTAGSETTTASTSGSETNTACTTGSE--------TSTPSSAGSE-----T 1243

Query: 1203 NTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGF 1254
            NT     S   ++S +  +P A       +TT  +T + +   S    S+ F
Sbjct: 1244 NTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTF 1295


>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 91/501 (18%), Positives = 183/501 (36%), Gaps = 25/501 (4%)

Query: 876  TTLSNSVVNEPPR-SYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQ 934
            TT+++++ +E  + S  S +++ ++ +     +A+  A+  T  S   S + P      +
Sbjct: 782  TTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSE 841

Query: 935  PESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPI 994
              +                S + T       + T  T+ S  T  S              
Sbjct: 842  TTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTT----- 896

Query: 995  HHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLT 1054
              S E  E + +S     +T V    +      ++   T     + S+    S++  S T
Sbjct: 897  --STEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-SET 953

Query: 1055 EMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRV-SER 1113
                   + +   T    E ++     +  + +    S T T S+   +  +     SE 
Sbjct: 954  ITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSET 1013

Query: 1114 SSAGAHKTDC-LKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTM 1172
            ++     T+  +   E  ET  +      + +V+T   +     ++GS  ++    V+T 
Sbjct: 1014 TTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTT----VSTT 1069

Query: 1173 CNTKTDVITSAADTTSVSSWGGSEVISSLSNTILASTSSECVSSKSVSQPVAQKQECKVS 1232
             +  T   T+  +TT+VS+ G     +S + +   +T+     SK+ +      +   VS
Sbjct: 1070 GSETTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1233 TTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQT 1292
            TT+  T  +S TGS +         T  +     +A  ++A    +  + TE     ++T
Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE----GSET 1183

Query: 1293 LSASLPLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENS 1352
             +AS     T   ST     +  +   S+T+  +          T  SE    T+   ++
Sbjct: 1184 TTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSE----TSTPSSA 1239

Query: 1353 GNSVSEIIKPCSVNLIASTSS 1373
            G+  +      S   IAST+S
Sbjct: 1240 GSETNTAFIIGSETTIASTAS 1260



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 72/355 (20%), Positives = 137/355 (38%), Gaps = 33/355 (9%)

Query: 1091 SSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSE 1150
            ++ + T S   +   S   ++  S+AG+  T    ++ AG +G        S++  + + 
Sbjct: 46   TTPSPTGSQTTIVSISGSEITTTSTAGSENTT---VSSAG-SGTTTASMAGSETTVSTAG 101

Query: 1151 KNFQAVSQGSVPSSVMSAV------NTMCNTKTDVITSAADTTSVSSWGGSEVISSLS-- 1202
                 VS     ++++SA+      N+  +++T V ++A   T+  S  GSE  ++ +  
Sbjct: 102  SETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTAD 161

Query: 1203 --NTILASTSSECVS-----SKSVSQPVAQKQECKVSTTAPVTLASSKTGSV-VQPSSGF 1254
               T  ++T SE  +     S++++   A  +   VST    T   S TGS     S+  
Sbjct: 162  SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 1255 SGTT--DFIHLKKHKAALAAAQYKSSNA-SETEPNAIKNQTLSASLPLDSTVICSTINKA 1311
            S TT    +  +  K + A ++   S A SET   + ++   + +   DS    +T    
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK---TTTAST 278

Query: 1312 NSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSV-------SEIIKPCS 1364
                   AS T           +  T  S     T K+  + + V       SE I+  +
Sbjct: 279  TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338

Query: 1365 VNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKS 1419
            V    +T S   +   +  I+      D     +       GSE+  +    S++
Sbjct: 339  VGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 50/261 (19%), Positives = 96/261 (36%), Gaps = 15/261 (5%)

Query: 1128 EAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSA------VNTMCNTKTDVIT 1181
            E  ET  +        +V T+  +N    + GS  ++V +        +T  +  T V T
Sbjct: 509  EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVST 568

Query: 1182 SAADTTSVSSWGGSEVISSLSN----TILASTSSECVSSKSVSQPVAQKQECKVSTTAPV 1237
            + A+TT+ S+ G     +S +     T+  + S    +S + S+  +       +TTA  
Sbjct: 569  TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAST 628

Query: 1238 TLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASL 1297
            T + + T S     +    TTD                 +  +  T  +A  ++T  ++ 
Sbjct: 629  TSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTE 688

Query: 1298 PLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWL-----TRHSEEDKNTNKMENS 1352
               +T +  T ++   V    +  T+     +++  A +     T  S E   T      
Sbjct: 689  GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 748

Query: 1353 GNSVSEIIKPCSVNLIASTSS 1373
            G+  +      S    AST+S
Sbjct: 749  GSETTSASTTGSETTTASTTS 769



 Score = 32.3 bits (72), Expect = 5.5
 Identities = 35/172 (20%), Positives = 65/172 (37%), Gaps = 19/172 (11%)

Query: 1083 MASVIVRPSSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNS 1142
            M +V    S +T   ++ +    S    SE ++     ++    + AG           +
Sbjct: 1143 MTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSE------TTTA 1196

Query: 1143 DSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISSLS 1202
             +  +++     A S+ +  S+  S  NT C T ++        TS  S  GSE     +
Sbjct: 1197 STAGSETTTASTAGSETTTASTSGSETNTACTTGSE--------TSTPSSAGSE-----T 1243

Query: 1203 NTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGF 1254
            NT     S   ++S +  +P A       +TT  +T + +   S    S+ F
Sbjct: 1244 NTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTF 1295


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 94/520 (18%), Positives = 195/520 (37%), Gaps = 25/520 (4%)

Query: 876  TTLSNSVVNEPPR-SYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQ 934
            TT+++++ +E  + S  S +++ ++ +     +A+  A+  T  S   S + P      +
Sbjct: 782  TTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSE 841

Query: 935  PESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPI 994
              +                S + T       + T  T+ S  T  S              
Sbjct: 842  TTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTT----- 896

Query: 995  HHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLT 1054
              S E  E + +S     +T V    +      ++   T     + S+    S++  S T
Sbjct: 897  --STEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-SET 953

Query: 1055 EMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRV-SER 1113
                   + +   T    E ++     +  + +    S T T S+   +  +     SE 
Sbjct: 954  ITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSET 1013

Query: 1114 SSAGAHKTDC-LKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTM 1172
            ++     T+  +   E  ET  +      + +V+T   +     ++GS  ++    V+T 
Sbjct: 1014 TTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTT----VSTT 1069

Query: 1173 CNTKTDVITSAADTTSVSSWGGSEVISSLSNTILASTSSECVSSKSVSQPVAQKQECKVS 1232
             +  T   T+  +TT+VS+ G     +S + +   +T+     SK+ +      +   VS
Sbjct: 1070 GSETTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1233 TTAPVTLASSKTGS-VVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNAS-----ETEPN 1286
            TT+  T  +S TGS +    +  S TT    +       +AA  +++  S      T  +
Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS 1187

Query: 1287 AIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQP-NYHTKLKKAWLTRHSEEDKN 1345
               ++T +AS     T   ST     +      S+TS P +  ++   A++        +
Sbjct: 1188 TAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIAS 1247

Query: 1346 TNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIV 1385
            T  +E +  S++   +  +V++ AS ++    +V S   V
Sbjct: 1248 TASLEPTATSLTG-SETTTVSITASGATAASTTVSSTTFV 1286



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 72/355 (20%), Positives = 137/355 (38%), Gaps = 33/355 (9%)

Query: 1091 SSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSE 1150
            ++ + T S   +   S   ++  S+AG+  T    ++ AG +G        S++  + + 
Sbjct: 46   TTPSPTGSQTTIVSISGSEITTTSTAGSENTT---VSSAG-SGTTTASMAGSETTVSTAG 101

Query: 1151 KNFQAVSQGSVPSSVMSAV------NTMCNTKTDVITSAADTTSVSSWGGSEVISSLS-- 1202
                 VS     ++++SA+      N+  +++T V ++A   T+  S  GSE  ++ +  
Sbjct: 102  SETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTAD 161

Query: 1203 --NTILASTSSECVS-----SKSVSQPVAQKQECKVSTTAPVTLASSKTGSV-VQPSSGF 1254
               T  ++T SE  +     S++++   A  +   VST    T   S TGS     S+  
Sbjct: 162  SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 1255 SGTT--DFIHLKKHKAALAAAQYKSSNA-SETEPNAIKNQTLSASLPLDSTVICSTINKA 1311
            S TT    +  +  K + A ++   S A SET   + ++   + +   DS    +T    
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK---TTTAST 278

Query: 1312 NSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSV-------SEIIKPCS 1364
                   AS T           +  T  S     T K+  + + V       SE I+  +
Sbjct: 279  TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338

Query: 1365 VNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKS 1419
            V    +T S   +   +  I+      D     +       GSE+  +    S++
Sbjct: 339  VGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 50/261 (19%), Positives = 96/261 (36%), Gaps = 15/261 (5%)

Query: 1128 EAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSA------VNTMCNTKTDVIT 1181
            E  ET  +        +V T+  +N    + GS  ++V +        +T  +  T V T
Sbjct: 509  EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVST 568

Query: 1182 SAADTTSVSSWGGSEVISSLSN----TILASTSSECVSSKSVSQPVAQKQECKVSTTAPV 1237
            + A+TT+ S+ G     +S +     T+  + S    +S + S+  +       +TTA  
Sbjct: 569  TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAST 628

Query: 1238 TLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASL 1297
            T + + T S     +    TTD                 +  +  T  +A  ++T  ++ 
Sbjct: 629  TSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTE 688

Query: 1298 PLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWL-----TRHSEEDKNTNKMENS 1352
               +T +  T ++   V    +  T+     +++  A +     T  S E   T      
Sbjct: 689  GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 748

Query: 1353 GNSVSEIIKPCSVNLIASTSS 1373
            G+  +      S    AST+S
Sbjct: 749  GSETTSASTTGSETTTASTTS 769


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 94/520 (18%), Positives = 195/520 (37%), Gaps = 25/520 (4%)

Query: 876  TTLSNSVVNEPPR-SYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQ 934
            TT+++++ +E  + S  S +++ ++ +     +A+  A+  T  S   S + P      +
Sbjct: 782  TTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSE 841

Query: 935  PESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPI 994
              +                S + T       + T  T+ S  T  S              
Sbjct: 842  TTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTT----- 896

Query: 995  HHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLT 1054
              S E  E + +S     +T V    +      ++   T     + S+    S++  S T
Sbjct: 897  --STEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-SET 953

Query: 1055 EMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRV-SER 1113
                   + +   T    E ++     +  + +    S T T S+   +  +     SE 
Sbjct: 954  ITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSET 1013

Query: 1114 SSAGAHKTDC-LKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTM 1172
            ++     T+  +   E  ET  +      + +V+T   +     ++GS  ++    V+T 
Sbjct: 1014 TTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTT----VSTT 1069

Query: 1173 CNTKTDVITSAADTTSVSSWGGSEVISSLSNTILASTSSECVSSKSVSQPVAQKQECKVS 1232
             +  T   T+  +TT+VS+ G     +S + +   +T+     SK+ +      +   VS
Sbjct: 1070 GSETTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1233 TTAPVTLASSKTGS-VVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNAS-----ETEPN 1286
            TT+  T  +S TGS +    +  S TT    +       +AA  +++  S      T  +
Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS 1187

Query: 1287 AIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQP-NYHTKLKKAWLTRHSEEDKN 1345
               ++T +AS     T   ST     +      S+TS P +  ++   A++        +
Sbjct: 1188 TAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIAS 1247

Query: 1346 TNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIV 1385
            T  +E +  S++   +  +V++ AS ++    +V S   V
Sbjct: 1248 TASLEPTATSLTG-SETTTVSITASGATAASTTVSSTTFV 1286



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 72/355 (20%), Positives = 137/355 (38%), Gaps = 33/355 (9%)

Query: 1091 SSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSE 1150
            ++ + T S   +   S   ++  S+AG+  T    ++ AG +G        S++  + + 
Sbjct: 46   TTPSPTGSQTTIVSISGSEITTTSTAGSENTT---VSSAG-SGTTTASMAGSETTVSTAG 101

Query: 1151 KNFQAVSQGSVPSSVMSAV------NTMCNTKTDVITSAADTTSVSSWGGSEVISSLS-- 1202
                 VS     ++++SA+      N+  +++T V ++A   T+  S  GSE  ++ +  
Sbjct: 102  SETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTAD 161

Query: 1203 --NTILASTSSECVS-----SKSVSQPVAQKQECKVSTTAPVTLASSKTGSV-VQPSSGF 1254
               T  ++T SE  +     S++++   A  +   VST    T   S TGS     S+  
Sbjct: 162  SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 1255 SGTT--DFIHLKKHKAALAAAQYKSSNA-SETEPNAIKNQTLSASLPLDSTVICSTINKA 1311
            S TT    +  +  K + A ++   S A SET   + ++   + +   DS    +T    
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK---TTTAST 278

Query: 1312 NSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSV-------SEIIKPCS 1364
                   AS T           +  T  S     T K+  + + V       SE I+  +
Sbjct: 279  TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338

Query: 1365 VNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKS 1419
            V    +T S   +   +  I+      D     +       GSE+  +    S++
Sbjct: 339  VGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 50/261 (19%), Positives = 96/261 (36%), Gaps = 15/261 (5%)

Query: 1128 EAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSA------VNTMCNTKTDVIT 1181
            E  ET  +        +V T+  +N    + GS  ++V +        +T  +  T V T
Sbjct: 509  EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVST 568

Query: 1182 SAADTTSVSSWGGSEVISSLSN----TILASTSSECVSSKSVSQPVAQKQECKVSTTAPV 1237
            + A+TT+ S+ G     +S +     T+  + S    +S + S+  +       +TTA  
Sbjct: 569  TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAST 628

Query: 1238 TLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASL 1297
            T + + T S     +    TTD                 +  +  T  +A  ++T  ++ 
Sbjct: 629  TSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTE 688

Query: 1298 PLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWL-----TRHSEEDKNTNKMENS 1352
               +T +  T ++   V    +  T+     +++  A +     T  S E   T      
Sbjct: 689  GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 748

Query: 1353 GNSVSEIIKPCSVNLIASTSS 1373
            G+  +      S    AST+S
Sbjct: 749  GSETTSASTTGSETTTASTTS 769


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 94/520 (18%), Positives = 195/520 (37%), Gaps = 25/520 (4%)

Query: 876  TTLSNSVVNEPPR-SYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQ 934
            TT+++++ +E  + S  S +++ ++ +     +A+  A+  T  S   S + P      +
Sbjct: 782  TTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSE 841

Query: 935  PESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPI 994
              +                S + T       + T  T+ S  T  S              
Sbjct: 842  TTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTT----- 896

Query: 995  HHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLT 1054
              S E  E + +S     +T V    +      ++   T     + S+    S++  S T
Sbjct: 897  --STEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-SET 953

Query: 1055 EMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRV-SER 1113
                   + +   T    E ++     +  + +    S T T S+   +  +     SE 
Sbjct: 954  ITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSET 1013

Query: 1114 SSAGAHKTDC-LKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTM 1172
            ++     T+  +   E  ET  +      + +V+T   +     ++GS  ++    V+T 
Sbjct: 1014 TTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTT----VSTT 1069

Query: 1173 CNTKTDVITSAADTTSVSSWGGSEVISSLSNTILASTSSECVSSKSVSQPVAQKQECKVS 1232
             +  T   T+  +TT+VS+ G     +S + +   +T+     SK+ +      +   VS
Sbjct: 1070 GSETTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1233 TTAPVTLASSKTGS-VVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNAS-----ETEPN 1286
            TT+  T  +S TGS +    +  S TT    +       +AA  +++  S      T  +
Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS 1187

Query: 1287 AIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQP-NYHTKLKKAWLTRHSEEDKN 1345
               ++T +AS     T   ST     +      S+TS P +  ++   A++        +
Sbjct: 1188 TAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAS 1247

Query: 1346 TNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIV 1385
            T  +E +  S++   +  +V++ AS ++    +V S   V
Sbjct: 1248 TASLEPTATSLTG-SETTTVSITASGATAASTTVSSTTFV 1286



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 72/355 (20%), Positives = 137/355 (38%), Gaps = 33/355 (9%)

Query: 1091 SSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSE 1150
            ++ + T S   +   S   ++  S+AG+  T    ++ AG +G        S++  + + 
Sbjct: 46   TTPSPTGSQTTIVSISGSEITTTSTAGSENTT---VSSAG-SGTTTASMAGSETTVSTAG 101

Query: 1151 KNFQAVSQGSVPSSVMSAV------NTMCNTKTDVITSAADTTSVSSWGGSEVISSLS-- 1202
                 VS     ++++SA+      N+  +++T V ++A   T+  S  GSE  ++ +  
Sbjct: 102  SETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTAD 161

Query: 1203 --NTILASTSSECVS-----SKSVSQPVAQKQECKVSTTAPVTLASSKTGSV-VQPSSGF 1254
               T  ++T SE  +     S++++   A  +   VST    T   S TGS     S+  
Sbjct: 162  SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 1255 SGTT--DFIHLKKHKAALAAAQYKSSNA-SETEPNAIKNQTLSASLPLDSTVICSTINKA 1311
            S TT    +  +  K + A ++   S A SET   + ++   + +   DS    +T    
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK---TTTAST 278

Query: 1312 NSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSV-------SEIIKPCS 1364
                   AS T           +  T  S     T K+  + + V       SE I+  +
Sbjct: 279  TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338

Query: 1365 VNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKS 1419
            V    +T S   +   +  I+      D     +       GSE+  +    S++
Sbjct: 339  VGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 50/261 (19%), Positives = 96/261 (36%), Gaps = 15/261 (5%)

Query: 1128 EAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSA------VNTMCNTKTDVIT 1181
            E  ET  +        +V T+  +N    + GS  ++V +        +T  +  T V T
Sbjct: 509  EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVST 568

Query: 1182 SAADTTSVSSWGGSEVISSLSN----TILASTSSECVSSKSVSQPVAQKQECKVSTTAPV 1237
            + A+TT+ S+ G     +S +     T+  + S    +S + S+  +       +TTA  
Sbjct: 569  TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAST 628

Query: 1238 TLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASL 1297
            T + + T S     +    TTD                 +  +  T  +A  ++T  ++ 
Sbjct: 629  TSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTE 688

Query: 1298 PLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWL-----TRHSEEDKNTNKMENS 1352
               +T +  T ++   V    +  T+     +++  A +     T  S E   T      
Sbjct: 689  GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 748

Query: 1353 GNSVSEIIKPCSVNLIASTSS 1373
            G+  +      S    AST+S
Sbjct: 749  GSETTSASTTGSETTTASTTS 769


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 94/520 (18%), Positives = 195/520 (37%), Gaps = 25/520 (4%)

Query: 876  TTLSNSVVNEPPR-SYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQ 934
            TT+++++ +E  + S  S +++ ++ +     +A+  A+  T  S   S + P      +
Sbjct: 803  TTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSE 862

Query: 935  PESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPI 994
              +                S + T       + T  T+ S  T  S              
Sbjct: 863  TTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTT----- 917

Query: 995  HHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLT 1054
              S E  E + +S     +T V    +      ++   T     + S+    S++  S T
Sbjct: 918  --STEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-SET 974

Query: 1055 EMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRV-SER 1113
                   + +   T    E ++     +  + +    S T T S+   +  +     SE 
Sbjct: 975  ITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSET 1034

Query: 1114 SSAGAHKTDC-LKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTM 1172
            ++     T+  +   E  ET  +      + +V+T   +     ++GS  ++    V+T 
Sbjct: 1035 TTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTT----VSTT 1090

Query: 1173 CNTKTDVITSAADTTSVSSWGGSEVISSLSNTILASTSSECVSSKSVSQPVAQKQECKVS 1232
             +  T   T+  +TT+VS+ G     +S + +   +T+     SK+ +      +   VS
Sbjct: 1091 GSETTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGSKTTTASTEGSEATTVS 1148

Query: 1233 TTAPVTLASSKTGS-VVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNAS-----ETEPN 1286
            TT+  T  +S TGS +    +  S TT    +       +AA  +++  S      T  +
Sbjct: 1149 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS 1208

Query: 1287 AIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQP-NYHTKLKKAWLTRHSEEDKN 1345
               ++T +AS     T   ST     +      S+TS P +  ++   A++        +
Sbjct: 1209 TAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAS 1268

Query: 1346 TNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIV 1385
            T  +E +  S++   +  +V++ AS ++    +V S   V
Sbjct: 1269 TASLEPTATSLTG-SETTTVSITASGATAASTTVSSTTFV 1307



 Score = 40.0 bits (92), Expect = 0.027
 Identities = 73/355 (20%), Positives = 137/355 (38%), Gaps = 33/355 (9%)

Query: 1091 SSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSE 1150
            ++ + T S   +   S   ++  S+AG+  T    ++ AG +G        S+S  + + 
Sbjct: 67   TTPSPTGSQTTIVSISGSEITTTSTAGSENTT---VSSAG-SGTTTASMAGSESTISTAG 122

Query: 1151 KNFQAVSQGSVPSSVMSAV------NTMCNTKTDVITSAADTTSVSSWGGSEVISSLS-- 1202
                 VS     ++++SA+      N+  +++T V ++A   T+  S  GSE  ++ +  
Sbjct: 123  SETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTAD 182

Query: 1203 --NTILASTSSECVS-----SKSVSQPVAQKQECKVSTTAPVTLASSKTGSV-VQPSSGF 1254
               T  ++T SE  +     S++++   A  +   VST    T   S TGS     S+  
Sbjct: 183  SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 242

Query: 1255 SGTT--DFIHLKKHKAALAAAQYKSSNA-SETEPNAIKNQTLSASLPLDSTVICSTINKA 1311
            S TT    +  +  K + A ++   S A SET   + ++   + +   DS    +T    
Sbjct: 243  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK---TTTAST 299

Query: 1312 NSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSV-------SEIIKPCS 1364
                   AS T           +  T  S     T K+  + + V       SE I+  +
Sbjct: 300  TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 359

Query: 1365 VNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKS 1419
            V    +T S   +   +  I+      D     +       GSE+  +    S++
Sbjct: 360  VGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 414



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 50/261 (19%), Positives = 96/261 (36%), Gaps = 15/261 (5%)

Query: 1128 EAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSA------VNTMCNTKTDVIT 1181
            E  ET  +        +V T+  +N    + GS  ++V +        +T  +  T V T
Sbjct: 530  EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVST 589

Query: 1182 SAADTTSVSSWGGSEVISSLSN----TILASTSSECVSSKSVSQPVAQKQECKVSTTAPV 1237
            + A+TT+ S+ G     +S +     T+  + S    +S + S+  +       +TTA  
Sbjct: 590  TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAST 649

Query: 1238 TLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASL 1297
            T + + T S     +    TTD                 +  +  T  +A  ++T  ++ 
Sbjct: 650  TSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTE 709

Query: 1298 PLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWL-----TRHSEEDKNTNKMENS 1352
               +T +  T ++   V    +  T+     +++  A +     T  S E   T      
Sbjct: 710  GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 769

Query: 1353 GNSVSEIIKPCSVNLIASTSS 1373
            G+  +      S    AST+S
Sbjct: 770  GSETTSASTTGSETTTASTTS 790


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
            sapiens]
          Length = 1521

 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 94/520 (18%), Positives = 195/520 (37%), Gaps = 25/520 (4%)

Query: 876  TTLSNSVVNEPPR-SYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQ 934
            TT+++++ +E  + S  S +++ ++ +     +A+  A+  T  S   S + P      +
Sbjct: 782  TTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSE 841

Query: 935  PESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPI 994
              +                S + T       + T  T+ S  T  S              
Sbjct: 842  TTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTT----- 896

Query: 995  HHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLT 1054
              S E  E + +S     +T V    +      ++   T     + S+    S++  S T
Sbjct: 897  --STEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG-SET 953

Query: 1055 EMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRV-SER 1113
                   + +   T    E ++     +  + +    S T T S+   +  +     SE 
Sbjct: 954  ITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSET 1013

Query: 1114 SSAGAHKTDC-LKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTM 1172
            ++     T+  +   E  ET  +      + +V+T   +     ++GS  ++    V+T 
Sbjct: 1014 TTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTT----VSTT 1069

Query: 1173 CNTKTDVITSAADTTSVSSWGGSEVISSLSNTILASTSSECVSSKSVSQPVAQKQECKVS 1232
             +  T   T+  +TT+VS+ G     +S + +   +T+     SK+ +      +   VS
Sbjct: 1070 GSETTTASTADLETTTVSTSGSGTTTASTAGS--ETTTVYITGSKTTTASTEGSEATTVS 1127

Query: 1233 TTAPVTLASSKTGS-VVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNAS-----ETEPN 1286
            TT+  T  +S TGS +    +  S TT    +       +AA  +++  S      T  +
Sbjct: 1128 TTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS 1187

Query: 1287 AIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQP-NYHTKLKKAWLTRHSEEDKN 1345
               ++T +AS     T   ST     +      S+TS P +  ++   A++        +
Sbjct: 1188 TAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAS 1247

Query: 1346 TNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIV 1385
            T  +E +  S++   +  +V++ AS ++    +V S   V
Sbjct: 1248 TASLEPTATSLTG-SETTTVSITASGATAASTTVSSTTFV 1286



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 72/355 (20%), Positives = 137/355 (38%), Gaps = 33/355 (9%)

Query: 1091 SSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSE 1150
            ++ + T S   +   S   ++  S+AG+  T    ++ AG +G        S++  + + 
Sbjct: 46   TTPSPTGSQTTIVSISGSEITTTSTAGSENTT---VSSAG-SGTTTASMAGSETTVSTAG 101

Query: 1151 KNFQAVSQGSVPSSVMSAV------NTMCNTKTDVITSAADTTSVSSWGGSEVISSLS-- 1202
                 VS     ++++SA+      N+  +++T V ++A   T+  S  GSE  ++ +  
Sbjct: 102  SETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTAD 161

Query: 1203 --NTILASTSSECVS-----SKSVSQPVAQKQECKVSTTAPVTLASSKTGSV-VQPSSGF 1254
               T  ++T SE  +     S++++   A  +   VST    T   S TGS     S+  
Sbjct: 162  SETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAH 221

Query: 1255 SGTT--DFIHLKKHKAALAAAQYKSSNA-SETEPNAIKNQTLSASLPLDSTVICSTINKA 1311
            S TT    +  +  K + A ++   S A SET   + ++   + +   DS    +T    
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSK---TTTAST 278

Query: 1312 NSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSV-------SEIIKPCS 1364
                   AS T           +  T  S     T K+  + + V       SE I+  +
Sbjct: 279  TGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAST 338

Query: 1365 VNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKS 1419
            V    +T S   +   +  I+      D     +       GSE+  +    S++
Sbjct: 339  VGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA 393



 Score = 36.6 bits (83), Expect = 0.29
 Identities = 89/508 (17%), Positives = 169/508 (33%), Gaps = 51/508 (10%)

Query: 876  TTLSNSVVNEPPR-SYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQ 934
            TT+++++  E  + S  S EV+ ++        A+   +  T  S   S +    ++  +
Sbjct: 303  TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSE 362

Query: 935  PESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPI 994
              ++   G           S + T       + T  T  S  T  S        V     
Sbjct: 363  TSTDSTTG-----------SETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS 411

Query: 995  HHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLT 1054
              +    EGS  +    T+      +  G           I    DS+    S+     T
Sbjct: 412  ETTTTCTEGSEMTAVSTTVFETTTASTEGS-------EITIASTSDSETTTASTEGSETT 464

Query: 1055 EMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRVSERS 1114
             +    +      T      ++        +V    S +T   +  +   A     SE +
Sbjct: 465  TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMT 524

Query: 1115 SAGAHKTDCLKLAEAG-ETGRIILPNVNSDSVHTKSEKNFQAVSQG------SVPSSVMS 1167
            +     ++   ++  G ET  +    + + +  T+  +     + G      S   S  +
Sbjct: 525  TVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTT 584

Query: 1168 AVNTMCNTKTDVITSAADTTSVSSWGGSEVISSLSNTILASTSSECVSSKSVSQPVAQKQ 1227
            A +T  +  T V T+ ++ T+ S+       +S S T   +T++   SS++ +      +
Sbjct: 585  AASTAGSETTTVSTADSENTTAST--ADSETTSASTTGSETTTASTTSSETTTASTEGSE 642

Query: 1228 ECKVSTTAPVTLASSKTGS--VVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEP 1285
               VSTT   T   S TGS   +  + G   TT                  S+  SET  
Sbjct: 643  TTTVSTTDSETTMVSTTGSERTITSTEGSETTT-----------------VSATGSETTV 685

Query: 1286 NAIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKN 1345
            +   + T + S+    T   ST     ++ + + S+ +       +  +  T  S E   
Sbjct: 686  STEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITT----ASITGSETTTASTEGSE 741

Query: 1346 TNKMENSGNSVSEIIKPCSVNLIASTSS 1373
            T      G+  +      S    AST+S
Sbjct: 742  TTTASTEGSETTSASTTGSETTTASTTS 769


>gi|20070262 TNF receptor-associated factor 3 interacting protein 1
           isoform 1 [Homo sapiens]
          Length = 691

 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 65/294 (22%), Positives = 117/294 (39%), Gaps = 43/294 (14%)

Query: 25  DDVVHSLLKGEN------IGITSRRRSRANQNVNAVHSHYTRAQANSPRPAMNSQAAVPK 78
           DD V  +L GE         +TSR +   N+NV    S   R   N+        A + +
Sbjct: 122 DDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEES---RVHKNTED---RGDAEIKE 175

Query: 79  QNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKPEE 138
           ++T + ++Q+      RK  +    D+EK KE   +    GE  + K       R +P+ 
Sbjct: 176 RSTSRDRKQKEELKEDRKPREKD-KDKEKAKENGGNRHREGERERAK------ARARPDN 228

Query: 139 DEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKPH 198
           + +K    R R           D ++  K+  +  SE   E E       + + ++GK  
Sbjct: 229 ERQKDRGNRER-----------DRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDR 277

Query: 199 NNEKAGEETLKNSQPPWDQIQE-DKKHEEAEKRKSVDTQLQE---DMIIHSSEQST---V 251
           +  +     +KN +  WD  +E +++H++ EK+ +   ++ +   D     S+  T   +
Sbjct: 278 DRRR-----VKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEI 332

Query: 252 SDHNSNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLEKVAQE 305
           S   S  L  +       +++E   KE  +S       V  I N+ N E    E
Sbjct: 333 STRASKSLTTKTSKRRSKNSVE-GRKEDNISAKSLDSIVSGINNEPNQETTTSE 385


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 56/261 (21%), Positives = 109/261 (41%), Gaps = 49/261 (18%)

Query: 91  RPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKH--LMNKRRKPEEDEKKLNMKRL 148
           R + +K       D++K   +KY   +  E+   K+      N ++  + D+KK + K++
Sbjct: 344 RKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKI 403

Query: 149 RTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGE----EGKPHNNEKAG 204
                  FS  S+SE  +K    +  + K +++  NK + K + E    + +P  + K G
Sbjct: 404 T------FSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKG 457

Query: 205 EETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLPQEC 264
           ++  K  +   D  ++DKK +   K+ +  T+++ D+                     E 
Sbjct: 458 KKDEKKGKK--DSKKDDKKKD--AKKNAESTEMESDL---------------------EL 492

Query: 265 NMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLEKVAQENSSTFGLQTLQKMDPNVSD 324
             DK H+ E    +K + +        D   DT       + SS  G +T  K+  + ++
Sbjct: 493 KKDKKHSKEKKGSKKDIKK--------DARKDTESTDAEFDESSKTGFKTSTKIKGSDTE 544

Query: 325 SKHSIANAKFLETAKKDSDQS 345
           S+ S+    +   AKK  D+S
Sbjct: 545 SEESL----YKPGAKKKIDES 561



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 63/256 (24%), Positives = 100/256 (39%), Gaps = 8/256 (3%)

Query: 1210 SSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAA 1269
            S + V  K+  Q  A K   K S     +   SK+ S   P S  S T      +K K  
Sbjct: 144  SKQIVEEKTKRQNEADKTPLKSSHENEQS-KKSKSSSETNPESQNSKTVSKNCSQKDKKD 202

Query: 1270 LAAAQYKSSNASETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQPNYHT 1329
               ++  ++    T+ N  K+   S +     + ICS     NS+         Q +  +
Sbjct: 203  SKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSE----NSLNVDFLMLVGQSDDES 258

Query: 1330 KLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYV 1389
                AWL  +S+ +     ++ +  +  +  K    +  A +        DSK +     
Sbjct: 259  INFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVK 318

Query: 1390 KDDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQKRKGEIEE-D 1448
            KDDK    K K T  + +ESGDS + E K  ++ K++ K   KKK         + E  D
Sbjct: 319  KDDKKKDVK-KDTESTDAESGDS-KDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGD 376

Query: 1449 LKPNGVLSRSAKERSK 1464
             K     SR+ K+ SK
Sbjct: 377  AKDARNDSRNLKKASK 392



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 81/463 (17%), Positives = 166/463 (35%), Gaps = 52/463 (11%)

Query: 71  NSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISR----GENPKGKN 126
           N     P +++H+ +Q +     K K S  + P+ +  K    +   +     +N K  N
Sbjct: 156 NEADKTPLKSSHENEQSK-----KSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTN 210

Query: 127 KHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKN 186
              ++ +  P++D K+    +   D +S+    +        ++  S ++    +   +N
Sbjct: 211 TEFLHTKNNPKKDLKR---SKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRN 267

Query: 187 TSKINGEEGKPHNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQEDMIIHSS 246
            S+ N +       +   ++T KN++   D   ED K  + + +K      ++D      
Sbjct: 268 YSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVK 327

Query: 247 EQSTVSDHNSNDLLPQECNMDK-THTMELLPKEKFVSRPPTPK-----CVIDITNDTNLE 300
           + +  +D  S D   +  +  K    ++   K+K   + P           D  ND+   
Sbjct: 328 KDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNL 387

Query: 301 KVAQENSS--------TFGLQTLQKMDPNVS-------------DSKHSIANAKFLETAK 339
           K A +N          TF   +  +++   S             D+K S+ N +  E+  
Sbjct: 388 KKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDE--ESTD 445

Query: 340 KDSDQSWVSDVVKVDLTQSSVTNASSGNDHLNMEKEKYVSYISPLSAVSVMEDKLHKRSP 399
            DS+    S   K D  +       S  D    + +K        S + + +DK H +  
Sbjct: 446 ADSEPKGDSKKGKKDEKKG---KKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSK-- 500

Query: 400 PPETIKSKLNTSVDTHKIKSSPSPEVVKPKITHSPDSVKSKATYVNSQAT----GERRLA 455
             E   SK +   D  K   S   E  +   T    S K K +   S+ +    G ++  
Sbjct: 501 --EKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKI 558

Query: 456 NKIEHELSRCSFHPIPTRSSTLETTKSPLIIDKNEHFTVYRDP 498
           ++ +   +      + ++     ++K     +K E  +  R P
Sbjct: 559 DESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKASTGRVP 601



 Score = 40.8 bits (94), Expect = 0.016
 Identities = 59/300 (19%), Positives = 110/300 (36%), Gaps = 65/300 (21%)

Query: 1258 TDFIHLKKHKAALAAAQYKSSN-------------------ASETEPNAIKNQTLSASLP 1298
            T F HL   K  L  A+YK S                    A+  E   I  +       
Sbjct: 98   TPFRHLYTSKTHLKKAEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNE 157

Query: 1299 LDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMEN------- 1351
             D T + S+     S  +  +S+T+  + ++K      ++  ++D   +K  N       
Sbjct: 158  ADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTK 217

Query: 1352 ------------SGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRK- 1398
                        S + +SEI    S+N+       +  S D  I  D ++++   N  K 
Sbjct: 218  NNPKKDLKRSKTSNDPISEICSENSLNV--DFLMLVGQSDDESINFDAWLRNYSQNNSKN 275

Query: 1399 ---------AKRTYESGSESGDSDESESKSEQRTKRQPKPTYKK--KQNDLQK------- 1440
                      K T ++  +S D++  +SK  ++  ++ K   KK  K+ D++K       
Sbjct: 276  YSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDA 335

Query: 1441 ----RKGEIEEDLKPNGVLSRSAKERSKLKLQSNSNT--GIPRSVLKDWRKVKKLKQTGE 1494
                 K E ++  K    L +  K++   K   +++T  G  +    D R +KK  +  +
Sbjct: 336  ESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDD 395



 Score = 38.5 bits (88), Expect = 0.077
 Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 18/121 (14%)

Query: 1372 SSDIQNSVDSKIIVDKYVKDDKVNRRKAKRTYESGSESGDSD-------ESESKSEQRTK 1424
            S+D ++ ++SK       KD K ++   K++ ++  ES D+D       +   K E++ K
Sbjct: 406  STDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGK 465

Query: 1425 RQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSRSAKERSKLKLQSNSNTGIPRSVLKDWR 1484
            +  K   KKK         E+E DL           E  K K  S    G  + + KD R
Sbjct: 466  KDSKKDDKKKDAKKNAESTEMESDL-----------ELKKDKKHSKEKKGSKKDIKKDAR 514

Query: 1485 K 1485
            K
Sbjct: 515  K 515



 Score = 34.7 bits (78), Expect = 1.1
 Identities = 41/188 (21%), Positives = 77/188 (40%), Gaps = 26/188 (13%)

Query: 1338 RHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRR 1397
            + +++DK   K ++      +   P S +  +  + D +N  DS+ +      DDK    
Sbjct: 345  KDTKKDKKKLKKDDKKKDTKKY--PESTDTESGDAKDARN--DSRNLKKASKNDDKKKDA 400

Query: 1398 KAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSR 1457
            K K T+ + SES    +   K E++ K+  K   KK    ++  +   + D +P G   +
Sbjct: 401  K-KITFSTDSESELESKESQKDEKKDKKDSKTDNKK---SVKNDEESTDADSEPKGDSKK 456

Query: 1458 SAKERSKLKLQSNSNTGIPRSVLKDWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRL 1517
              K+  K K  S  +            K K  K+  ES        E+  +L+  ++ + 
Sbjct: 457  GKKDEKKGKKDSKKDD-----------KKKDAKKNAES-------TEMESDLELKKDKKH 498

Query: 1518 IRSKKGEE 1525
             + KKG +
Sbjct: 499  SKEKKGSK 506



 Score = 33.9 bits (76), Expect = 1.9
 Identities = 70/341 (20%), Positives = 121/341 (35%), Gaps = 57/341 (16%)

Query: 106 EKMKEEKYDYISRGENPKGKNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENS 165
           +K K+EK     + ++ K    +  N   K   +EK    KR    + +    S ++E S
Sbjct: 116 KKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKT---KRQNEADKTPLKSSHENEQS 172

Query: 166 NKRIIDNSSEQKPENE---LKNKNTSKINGEEGKPHNNEKAGEETLKNSQPPWDQIQEDK 222
            K    +SSE  PE++     +KN S+ + ++ K  N++K   E L     P   ++  K
Sbjct: 173 KKS--KSSSETNPESQNSKTVSKNCSQKDKKDSK--NSKKTNTEFLHTKNNPKKDLKRSK 228

Query: 223 KHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVS 282
              +       +  L  D ++   +    SD  S                          
Sbjct: 229 TSNDPISEICSENSLNVDFLMLVGQ----SDDES-------------------------- 258

Query: 283 RPPTPKCVIDITNDTNLEKVAQENSSTFGLQTLQ--KMDPNVSDSKHSIANAKFLETAKK 340
                     I  D  L   +Q NS  + L+  +  K D   +  K S A ++  + AKK
Sbjct: 259 ----------INFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKK 308

Query: 341 DS---DQSWVSDVVKVDLTQSSVTNASSGNDHLNMEKEKYVSYISPLSAVSVMEDKLHKR 397
           DS    ++   D  K D+ + + +  +   D  +  K+               + K +  
Sbjct: 309 DSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPE 368

Query: 398 SPPPET--IKSKLNTSVDTHKIKSSPSPEVVKPKITHSPDS 436
           S   E+   K   N S +  K   +   +    KIT S DS
Sbjct: 369 STDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDS 409


>gi|213385278 TNF receptor-associated factor 3 interacting protein 1
           isoform 2 [Homo sapiens]
          Length = 625

 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 85/423 (20%), Positives = 170/423 (40%), Gaps = 74/423 (17%)

Query: 25  DDVVHSLLKGEN------IGITSRRRSRANQNVNAVHSHYTRAQANSPRPAMNSQAAVPK 78
           DD V  +L GE         +TSR +   N+NV    S   R   N+        A + +
Sbjct: 122 DDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEES---RVHKNTED---RGDAEIKE 175

Query: 79  QNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKPEE 138
           ++T + ++Q+      RK  +    D+EK KE   +    GE  + K       R +P+ 
Sbjct: 176 RSTSRDRKQKEELKEDRKPREKD-KDKEKAKENGGNRHREGERERAK------ARARPDN 228

Query: 139 DEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKPH 198
           + +K    R R           D ++  K+  +  SE   E E       + + ++GK  
Sbjct: 229 ERQKDRGNRER-----------DRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDR 277

Query: 199 NNEKAGEETLKNSQPPWDQIQE-DKKHEEAEKRKSVDTQLQE---DMIIHSSEQST---V 251
           +  +     +KN +  WD  +E +++H++ EK+ +   ++ +   D     S+  T   +
Sbjct: 278 DRRR-----VKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEI 332

Query: 252 SDHNSNDLLPQECNMDKTHTME----------LLPKEKFVSR-PPTPKCVIDITNDTNLE 300
           S   S  L  +       +++E            P  +  S  P TP+   +++  +N+ 
Sbjct: 333 STRASKSLTTKTSKRRSKNSVEGDSTSDAEGDAGPAGQDKSEVPETPEIPNELS--SNIR 390

Query: 301 KVAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSV 360
           ++ +  S+      +++ D           + + L+  +  S ++ VS+V+       S 
Sbjct: 391 RIPRPGSARPAPPRVKRQD-----------SMEALQMDRSGSGKT-VSNVI-----TESH 433

Query: 361 TNASSGNDHLNMEKEKYVSYISPLSAVSVMEDKLHKRSPPPETIKSKLNTSVDTHKIKSS 420
            + +  +D   +E    +S +S +  V+ +E  L +       +K  L T  D  K++ S
Sbjct: 434 NSDNEEDDQFVVEAAPQLSEMSEIEMVTAVE--LEEEEKHGGLVKKILETKKDYEKLQQS 491

Query: 421 PSP 423
           P P
Sbjct: 492 PKP 494


>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
          Length = 248

 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 42/198 (21%), Positives = 80/198 (40%), Gaps = 14/198 (7%)

Query: 60  RAQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRG 119
           R    S  P +      P+    + ++Q     NK+ GS +    EEKM E     + + 
Sbjct: 20  RGPTQSVGPTIQDYLNRPRPTWEEVKKQLE---NKKTGSKALAEFEEKMNENWKKELEKS 76

Query: 120 ENPKGKNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPE 179
                      +K+R+ ++  KK   K  R+ + S  S+SS S + ++       E+K  
Sbjct: 77  REKLLSGNESSSKKRERKKKRKK---KSCRSSSSSSSSDSSSSSSDSE-----DEEKKQG 128

Query: 180 NELKNKNTSKINGEEGKPHNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQE 239
              K K        +   H +E   +E++K  +   D+ +++K      K++       +
Sbjct: 129 KRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDK 188

Query: 240 DMIIHSSEQSTVSDHNSN 257
            +   SSE S+ SD+  +
Sbjct: 189 PL---SSESSSESDYEED 203



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 47/199 (23%), Positives = 87/199 (43%), Gaps = 19/199 (9%)

Query: 1310 KANSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIA 1369
            K  S    +  +    N+  +L+K+     S  + ++ K E          K C  +  +
Sbjct: 52   KTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKK---KSCRSSSSS 108

Query: 1370 STSSDIQNSVDSKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKP 1429
            S+S    +S DS+   D+  K  K  ++K  R+Y+S   S    ESESK   + K++ K 
Sbjct: 109  SSSDSSSSSSDSE---DEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKD 165

Query: 1430 TYKKKQN--DLQKRKGEIEEDLKPNGVLSRS---------AKERSKLKLQSNSNTGIPRS 1478
              +K+++   L K++ +   D KP    S S         AK++ + + +  +   + + 
Sbjct: 166  ETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKK 225

Query: 1479 VLKDWRK--VKKLKQTGES 1495
              K  +K   KK K++G S
Sbjct: 226  KKKQHKKHSKKKKKKSGSS 244



 Score = 39.7 bits (91), Expect = 0.035
 Identities = 38/168 (22%), Positives = 81/168 (48%), Gaps = 11/168 (6%)

Query: 31  LLKGENIGITSRRRSRANQNVNAVHSHYTRAQANSPRPAMNSQAAVPKQNTHQQQQQ-RS 89
           LL G N   + +R  +  +   +  S  + + ++S   + +S+    KQ   +++++ RS
Sbjct: 80  LLSG-NESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRS 138

Query: 90  IRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKN-KHLMNKRRKPEEDEKKLNMKRL 148
            + ++    +S    +E +K++K    S+ E  K K+ + L  KR+K   D+K L+ +  
Sbjct: 139 YKSSQSSTHESESESKESVKKKKK---SKDETEKEKDVRSLSKKRKKSYPDDKPLSSE-- 193

Query: 149 RTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGK 196
            + + SD+ E  D +   KR  +   + K + + K K   K + ++ K
Sbjct: 194 -SSSESDYEE--DVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKK 238



 Score = 32.0 bits (71), Expect = 7.2
 Identities = 33/162 (20%), Positives = 64/162 (39%), Gaps = 14/162 (8%)

Query: 78  KQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKPE 137
           K N + +++    R     G++SS    E+ K+ K    S   +    +    +     E
Sbjct: 64  KMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKK--SCRSSSSSSSSDSSSSSSDSE 121

Query: 138 EDEKKLNMKRLRTDNVS--------DFSESSDSENSNKRIIDNSSEQKPENELKNKNTSK 189
           ++EKK   +R +  N S          SES   E+  K+       +K ++        K
Sbjct: 122 DEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRK 181

Query: 190 INGEEGKPHNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRK 231
            +  + KP ++E + E   +       Q ++ ++ EE E+ K
Sbjct: 182 KSYPDDKPLSSESSSESDYEEDV----QAKKKRRCEEREQAK 219


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 99/483 (20%), Positives = 164/483 (33%), Gaps = 92/483 (19%)

Query: 864  SVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITS 923
            S+P S P        S  V N P  S             +++ L+    +  T  +  T 
Sbjct: 3211 SIPTSTPSEGMTPLTSVPVSNTPVAS------------SEASILSTTPVDSNTPLTTSTE 3258

Query: 924  LSKPPPLIKHQPESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPA 983
             S  PP       +EG        +P    S   T   +   S T +  S T+TL + PA
Sbjct: 3259 ASSSPPT------AEGT------SMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPA 3306

Query: 984  LHRAPVF-------HPPIHHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIP 1036
                PV         PPI         +YS  S    TP+  ++       S +  TL  
Sbjct: 3307 DTSTPVTTYSQASSSPPIADGTSMPTSTYSEGS----TPLTNMSFSTTPVVSSEASTLST 3362

Query: 1037 EPKDSQANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKT 1096
             P D+     +S+E SL+       ++           S G    A   V   P  S++ 
Sbjct: 3363 TPVDTSTPVTTSTEASLSPTTAEGTSIPTSSP------SEGTTPLASMPVSTTPVVSSEV 3416

Query: 1097 DSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSEKNFQAV 1156
            +++    + S   V+  + A +  T    +AE        LP                  
Sbjct: 3417 NTLSTTPVDSNTLVTTSTEASSSPT----IAEGTS-----LPT--------------STT 3453

Query: 1157 SQGSVPSSVM---------SAVNTMCNTKTDVITSAADTTSVSSWGGSEVISSLSNTILA 1207
            S+GS P S+M         S  +T+  T  D  T    ++  +S   +  ++S+  +   
Sbjct: 3454 SEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAG 3513

Query: 1208 STSSECVSSKSVSQPVAQKQECKVSTT----------------APVTLASSKTGSVVQPS 1251
              S+   +    + PVA  +   +STT                +P TL  + T  +  PS
Sbjct: 3514 EGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVT-TMRMSTPS 3572

Query: 1252 SGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASLPLDSTVICSTINKA 1311
             G S  T  +    +  +  A+   + +   + P  +   T S S P    VI   ++  
Sbjct: 3573 EGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTP--VTTSTQSNSTPTPPEVITLPMSTP 3630

Query: 1312 NSV 1314
            + V
Sbjct: 3631 SEV 3633



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 126/577 (21%), Positives = 209/577 (36%), Gaps = 77/577 (13%)

Query: 835  SSSSSPKSHIIKQDMDVERSVSDLYKMKHSVPQSLPQSNYFTTLSNSV-----------V 883
            SS ++P+   +      E S+S       + P  LP    +T+L+  V            
Sbjct: 137  SSPTTPEGTDVPMSTPSEESISSTMAFVSTAP--LPSFEAYTSLTYKVDMSTPLTTSTQA 194

Query: 884  NEPPRSYPSKEVSNIYGDKQSNALAAAAANPQTLTSF--ITSLSKP-----PPLIKHQPE 936
            +  P +  S  +      + S  L +  A+   + S   IT L+ P     P  I  Q  
Sbjct: 195  SSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQAS 254

Query: 937  SEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVF-HPPIH 995
            S     + P  L +   S   T       S   +  S  +TL + PA    PV       
Sbjct: 255  SSPTTAEGPS-LSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEAS 313

Query: 996  HSLERKEGSYSSLSPPT--LTPVMPVNAGGKVQESQKPPTLIPEPKDSQANFKSSSEQSL 1053
             S    EG+    S  T   TP+    A      + +  TL   P D+     +S+E S 
Sbjct: 314  SSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSS 373

Query: 1054 TEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRVSER 1113
                    ++    T    E S+      +++++V  S ++ T ++P   + SK  V+  
Sbjct: 374  LPTTAEATSML---TSTLSEGSTPLTNMPVSTILVASSEASTTSTIP---VDSKTFVTTA 427

Query: 1114 SSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMC 1173
            S A +  T     + A  T     P+  S  + +        VS   V SS  S ++T  
Sbjct: 428  SEASSSPTTAEDTSIATST-----PSEGSTPLTS------MPVSTTPVASSEASNLST-- 474

Query: 1174 NTKTDVITSAADTTSVSSWGGSEVISSLSNTILASTSSECVSSKSVSQPVAQKQECKVST 1233
             T  D  T    +T  SS   +  ++S+  +  +  S+   S    + PVA  +   +ST
Sbjct: 475  -TPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLST 533

Query: 1234 T-----APVTLASSKTGSVVQP-------SSGFSGTTDFIHLKKHKAALAAAQYKSSNAS 1281
            T      PVT +S  + S   P       S+   G+T   ++      ++     SS AS
Sbjct: 534  TPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNM-----PVSTRLVVSSEAS 588

Query: 1282 ETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWLTRHSE 1341
             T           ++ P DS    +T ++A+S  +  A  TS P      +   +T  S 
Sbjct: 589  TT-----------STTPADSNTFVTTSSEASS-SSTTAEGTSMPTSTYSERGTTITSMSV 636

Query: 1342 EDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNS 1378
                    E S  S +    P   N   +TS++  +S
Sbjct: 637  STTLVASSEASTLSTT----PVDSNTPVTTSTEATSS 669



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 100/473 (21%), Positives = 179/473 (37%), Gaps = 58/473 (12%)

Query: 868  SLPQSNYFTTLSNSVVNEPPRSYPSKEVSN-IYGDKQSNALAAAA--ANPQTLTSFITSL 924
            S P +   T++  S ++E      S  VS+ +  + +++ L+     +N   +TS   S 
Sbjct: 1788 SSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSS 1847

Query: 925  SKPPPLIKHQPESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPAL 984
            S  P       E   +    P      + S  V+T        T +  S TNTL + PA+
Sbjct: 1848 SPTPA------EGTSIATSTPSEGSTALTSIPVST--------TTVASSETNTLSTTPAV 1893

Query: 985  HRAPV-FHPPIHHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQA 1043
               PV  +  +  S    +GS    S PT TP          +E + P T IP    + A
Sbjct: 1894 TSTPVTTYAQVSSSPTTADGS----SMPTSTP----------REGRPPLTSIPVSTTTVA 1939

Query: 1044 NFK-SSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAM 1102
            + + ++   +L +   P    S         ++S     A  + +  P+ S  +  + +M
Sbjct: 1940 SSEINTLSTTLADTRTPVTTYS---------QASSSPTTADGTSMPTPAYSEGSTPLTSM 1990

Query: 1103 QLASKDRV-SERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSV 1161
             L++   V SE S+      D    A     G          S+ T +         G  
Sbjct: 1991 PLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMP 2050

Query: 1162 PSS---VMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISSLSNTILASTSSECVSSKS 1218
             S+   V S  NT+  T  D  T   ++T  SS   +E  SS++ +  +  S    S   
Sbjct: 2051 VSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEG-SSMTISAPSEGSPLLTSIPL 2109

Query: 1219 VSQPVAQKQECKVSTT-----APVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAA 1273
             + PVA  +   +STT     +PV + S++  S   P+ G S  T        +  L + 
Sbjct: 2110 STTPVASPEASTLSTTPVDSNSPV-ITSTEVSSSPIPTEGTSMQTS--TYSDRRTPLTSM 2166

Query: 1274 QYKSSNASETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQPN 1326
               ++  + +  + +    +  S P+ ++   +    + +   G +  TS P+
Sbjct: 2167 PVSTTVVASSAISTLSTTPVDTSTPVTNS---TEARSSPTTSEGTSMPTSTPS 2216



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 97/467 (20%), Positives = 166/467 (35%), Gaps = 43/467 (9%)

Query: 872  SNYFTTLSNSVVNEPPRSYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPP--- 928
            SN     S  V + P  +  +   ++ Y D+++   +   +     +S I++LS  P   
Sbjct: 2129 SNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDT 2188

Query: 929  --PLIKHQPESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHR 986
              P+                 +P    S   T F +   S   +  S  +TL + P    
Sbjct: 2189 STPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTS 2248

Query: 987  APVF-HPPIHHSLERKEGSY---SSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQ 1042
             PV        S    EG+    S+LS  T TP+  +     +  + +  TL   P DS 
Sbjct: 2249 TPVTTSTEATSSPTTAEGTSIPTSTLSEGT-TPLTSIPVSHTLVANSEVSTLSTTPVDSN 2307

Query: 1043 ANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAM 1102
              F +S+E S         ++    +      S G        V     +S +T ++   
Sbjct: 2308 TPFTTSTEASSPPPTAEGTSMPTSTS------SEGNTPLTRMPVSTTMVASFETSTLSTT 2361

Query: 1103 QLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVP 1162
               +   V+  S AG+                   P    D+    S  +  +    SVP
Sbjct: 2362 PADTSTPVTTYSQAGSS------------------PTTADDTSMPTSTYSEGSTPLTSVP 2403

Query: 1163 SSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISSLSNTILASTSSE---CVSSKSV 1219
             S M  V++  +T +      +   + S+   S   ++   +I  S  SE    ++S  V
Sbjct: 2404 VSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPV 2463

Query: 1220 SQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSN 1279
            S       E    +T PV  ++  T S    SS    T + I +    A+  +    S  
Sbjct: 2464 STTPVVSSEAGTLSTTPVDTSTPMTTSTEASSS--PTTAEDIVVPISTASEGSTLLTSIP 2521

Query: 1280 ASETEPNAIKNQTLSASLPLDST--VICST-INKANSVGNGQASQTS 1323
             S T   + +  TLS + P+DS   V+ ST I+ + +   G +  TS
Sbjct: 2522 VSTTPVASPEASTLSTT-PVDSNSPVVTSTEISSSATSAEGTSMPTS 2567



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 93/428 (21%), Positives = 156/428 (36%), Gaps = 50/428 (11%)

Query: 912  ANPQTLTSFITSLSKPPPLIKHQPESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLT 971
            A+P+  T   T +    P++     S          +P    S   T  R+   S   L 
Sbjct: 2528 ASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLA 2587

Query: 972  VSSTNTLRSMPALHRAPVFHPPIHHSLERKEGSYSSLSPPTLTPV-MPVNAGGKVQESQK 1030
             S  +TL + P     PV              + +S SP T     MP++   +V  S  
Sbjct: 2588 SSEASTLSTTPVDTSIPV-----------TTSTETSSSPTTAKDTSMPISTPSEVSTSLT 2636

Query: 1031 PPTLIPEP-KDSQANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVR 1089
               +   P   S+A+  S++      +   +   S   T    E SS             
Sbjct: 2637 SILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTT--AEGSS------------M 2682

Query: 1090 PSSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKS 1149
            P+S+    S P   +     +   S A    T  +      +T   +  +  + S  T +
Sbjct: 2683 PTSTPGERSTPLTNILVSTTLLANSEASTLSTTPV------DTSTPVTTSAEASSSPTTA 2736

Query: 1150 EKNFQAVS---QGSVP--SSVMSAVNTMCNTKTDVITSAADT-------TSVSSWGGSEV 1197
            E     +S    GS P  S ++S +    +  + V T+A DT       T  SS   +  
Sbjct: 2737 EGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAE 2796

Query: 1198 ISSLSNTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGT 1257
            ++S+  +  + TS+   S      PVA  +   +STT PV  ++  T S    SS    T
Sbjct: 2797 VTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTT-PVDTSTPVTTSTKASSS--PTT 2853

Query: 1258 TDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNG 1317
             + I +    A+  +    S   S T   + +  TLS + P+D+++  +T  + +S    
Sbjct: 2854 AEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTT-PVDTSIPVTTSTEGSS-SPT 2911

Query: 1318 QASQTSQP 1325
             A  TS P
Sbjct: 2912 TAEGTSMP 2919



 Score = 38.5 bits (88), Expect = 0.077
 Identities = 111/538 (20%), Positives = 194/538 (36%), Gaps = 103/538 (19%)

Query: 864  SVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNI-YGDKQSNALAAAAANPQTLTSFIT 922
            S   S P +   T+++ S  +E      S  VS       +++ L+    + +T  +  T
Sbjct: 428  SEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTST 487

Query: 923  SLSKPPPL--IKHQPESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRS 980
              S  PP   +   P S    G  P      + S SV+T          +  S  +TL +
Sbjct: 488  EASSSPPTAEVNSMPTSTPSEGSTP------LTSMSVSTMP--------VASSEASTLST 533

Query: 981  MPALHRAPVFHPPIHHSLERKEGSYSSLSP-----PTLTPV--------MPVNAGGKVQE 1027
             P     PV            E S SS +P     PT TP         MPV+   ++  
Sbjct: 534  TPVDTSTPV--------TTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVST--RLVV 583

Query: 1028 SQKPPTLIPEPKDSQANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVI 1087
            S +  T    P DS     +SSE S +       ++    T  + E+ +     ++++ +
Sbjct: 584  SSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMP---TSTYSERGTTITSMSVSTTL 640

Query: 1088 VRPS-----SSTKTDSMPAMQLASKDRVSERSSAGAH------------------KTDCL 1124
            V  S     S+T  DS   +  +++   S  ++ G                     T  +
Sbjct: 641  VASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLV 700

Query: 1125 KLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNT----MCNTKTDVI 1180
              +EA       +      +  T++  +       S+P+S  S  +T    M  +KT + 
Sbjct: 701  ASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLT 760

Query: 1181 TSAADTTSVSSWGGSEVISSLSNTILASTSSE--------------CVSSKSVS-QPVAQ 1225
            +S A T S +    S  I++ +    + T++E               ++S  VS  PV  
Sbjct: 761  SSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTS 820

Query: 1226 KQECKVSTT-----APVTLASSKTGSVVQPSSGFS--------GTTDFIHLKKHKAALAA 1272
             +   +STT     +PVT  S++  S   P+ G S        G T    +      +A 
Sbjct: 821  PEASTLSTTPVDSNSPVT-TSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVAT 879

Query: 1273 AQYKSSNASETEPNA-IKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQPNYHT 1329
            +   + + +  + +  + N T + S P  S     T    ++ G G    TS P+  T
Sbjct: 880  SAISTLSTTPVDTSTPVTNSTEARSSPTTSE---GTSMPTSTPGEGSTPLTSMPDSTT 934



 Score = 37.4 bits (85), Expect = 0.17
 Identities = 109/508 (21%), Positives = 188/508 (37%), Gaps = 72/508 (14%)

Query: 831  SRVASSSSSPKSHIIKQDMDVERSVSDLYKMKHSVPQSLPQSNYFTTLSNSVVNEPPRSY 890
            S  ++ S++P    I      E S S       S+P S P S   T L++  V+      
Sbjct: 1116 SEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTS-PPSEGTTPLASMPVS------ 1168

Query: 891  PSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQPESEGLVGKIPEHLPH 950
                 + +    ++N L+    + +T  +  T  S PPP  +        V  +P   P 
Sbjct: 1169 -----TTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAE--------VTSMPTSTPG 1215

Query: 951  QIAS--HSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPIHHSLERKEGSYSSL 1008
            + ++   S+        S    T+S++    S P    A     P          S +S 
Sbjct: 1216 ERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSE 1275

Query: 1009 SPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQ-----ANFKSSSEQSLTEMWRPNNNL 1063
                LT + PV+    +  S +  TL+  P D++     +N  SSS         P +  
Sbjct: 1276 GSTLLTSI-PVST--TLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTY 1332

Query: 1064 SKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRVSERSSAGAHKTDC 1123
            S+ +T       +  L A+ A  I+   S+T  D+   +  +++   S  +S G      
Sbjct: 1333 SEGRTPLTSIPVNTTLVASSAISIL---STTPVDNSTPVTTSTEACSSPTTSEGTS---- 1385

Query: 1124 LKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNT--KTDVIT 1181
                         +PN N     T            S+P S    V++  +T   T V T
Sbjct: 1386 -------------MPNSNPSEGTTPLT---------SIPVSTTPVVSSEASTLSATPVDT 1423

Query: 1182 SAADTTSVSSWGGSEVISSLSNTILASTSSECVSS-KSV---SQPVAQKQECKVSTTAPV 1237
            S   TTS  +         +S  I  ST SE  +  KS+   + PVA  +   +STT   
Sbjct: 1424 STPGTTSAEATSSPTTAEGIS--IPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVD 1481

Query: 1238 TLASSKTGSVVQPS-SGFSGTTDFIHL-KKHKAALAAAQYKSSNASETEPNAIKNQTLSA 1295
            + +   T + V  S +   GT+  I    +   AL +    ++  + +E N++       
Sbjct: 1482 SNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVT 1541

Query: 1296 SLPLDSTVICSTINKANSVGNGQASQTS 1323
            S P+ +    S  + + +  +G + QTS
Sbjct: 1542 STPVTT---YSQASSSPTTADGTSMQTS 1566


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 59/331 (17%), Positives = 130/331 (39%), Gaps = 34/331 (10%)

Query: 35  ENIGITSRRRSRANQNVNAVHSHYTRAQANSPRPAMNS-QAAVPKQNTHQQQQQRSIRPN 93
           E + +    +S    NV  +     RA+   P+   N+ Q  + +Q    ++Q++ IR  
Sbjct: 232 EKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ 291

Query: 94  KRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKPEEDEKKL-NMKRLRTDN 152
           + K        EE+++E++     + E    + K L  + ++  E EK+L   K LR   
Sbjct: 292 EEK----MWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQE 347

Query: 153 VSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKPHNNE----------K 202
                +        +++ +   +   + E   +   ++  +E K  + E          +
Sbjct: 348 EQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLR 407

Query: 203 AGEETLKNSQPPWDQIQ---EDKKHEEAEKR-KSVDTQLQEDMIIHSSEQSTVSDHNSND 258
             EE ++  +  W+Q++   E+KK +E EK+ +  + ++QE+  I   E+    +  +  
Sbjct: 408 EKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMR 467

Query: 259 LLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLEKVAQENSSTFGLQTLQKM 318
              ++    + +  E   KE    R P  K           EK+ ++       + + + 
Sbjct: 468 EQEEKMQKQEENMWEQEEKEWQQQRLPEQK-----------EKLWEQEKMQEQEEKIWEQ 516

Query: 319 DPNVSDSKHSIANAKFL---ETAKKDSDQSW 346
           +  + D +      K +   E  ++  DQ W
Sbjct: 517 EEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 547



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 41/216 (18%), Positives = 89/216 (41%), Gaps = 14/216 (6%)

Query: 70  MNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHL 129
           M  +    ++ T  Q+++       R+       +EE M+E++     + E  + + + +
Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM 626

Query: 130 MNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSK 189
             +  K +E E+K+       +      E  +     +R +    E+  E+E K +   K
Sbjct: 627 WEQEEKMQEQEEKM------WEQEEKMWEQEEKMWEQQR-LPEQKEKLWEHE-KMQEQEK 678

Query: 190 INGEEGKPHNNEKAGEETLKNSQPPWDQ--IQEDKKHEEAEKRKSVDTQLQEDMIIHSSE 247
           +  +E K    EK  ++T +  +  WDQ  ++E++   E EK+   + ++  +      E
Sbjct: 679 MQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQE 738

Query: 248 QSTVSDHNSNDLLPQECNM----DKTHTMELLPKEK 279
           Q         ++  QE  M    +K    + LP++K
Sbjct: 739 QEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQK 774



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 30/176 (17%), Positives = 80/176 (45%), Gaps = 11/176 (6%)

Query: 70  MNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHL 129
           M  + ++ ++    ++++  +R  + K  +     EEKM+E++ +   + E    + + +
Sbjct: 709 MREEESMREREKKMREEEEMMREQEEKMQEQ----EEKMQEQEEEMWEQEEKMWEQEEKM 764

Query: 130 MNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSK 189
             ++R PE+ EK    ++++ +    + +     +  +++     + + + E       K
Sbjct: 765 WEQQRLPEQKEKLWEHEKMQ-EQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEK 823

Query: 190 INGEEGKPHNNEK---AGEETLKNSQPPWD---QIQEDKKHEEAEKRKSVDTQLQE 239
           + G+E K    E+     EE +   +   +   Q QE+K  E+ EK +  + +++E
Sbjct: 824 MWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMRE 879



 Score = 33.5 bits (75), Expect = 2.5
 Identities = 29/191 (15%), Positives = 79/191 (41%), Gaps = 2/191 (1%)

Query: 78  KQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKPE 137
           +Q+   ++++  +R  ++         EEK  +E+       E    + + +  + +K  
Sbjct: 401 EQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMR 460

Query: 138 EDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKP 197
           E+E+ +  +  +     +     + +   ++ +    E+  E E   +   KI  +E K 
Sbjct: 461 EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 520

Query: 198 HNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQL--QEDMIIHSSEQSTVSDHN 255
            + E+   +  K  +    + QED+  E+ EK +  + ++  QE+ +   +++      +
Sbjct: 521 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWD 580

Query: 256 SNDLLPQECNM 266
             + + +E  M
Sbjct: 581 QEEKMREEERM 591


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 70/309 (22%), Positives = 122/309 (39%), Gaps = 20/309 (6%)

Query: 1047 SSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLAS 1106
            +SSE S       +   S   T  + E S+   +A+ A+     S S+ T S  +    S
Sbjct: 158  TSSEASTATNSESSTTSSGASTATNSESSTVSSRASTAT----NSESSTTSSGASTATNS 213

Query: 1107 KDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQG------S 1160
            + R +   +  A  ++    +    T      +  S    T +       S G      S
Sbjct: 214  ESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNS 273

Query: 1161 VPSSVMSAVNTMCNTKTDVITSAADT-----TSVSSWGGSEVISSLSNTILASTSSECVS 1215
              S+V S ++T+ N+++   +S A+T     +S +S G +   +S S+T  +  S+   S
Sbjct: 274  ESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNS 333

Query: 1216 -SKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQ 1274
             S + S   +     + STT+     ++ +GS    SSG S  T+         A  A  
Sbjct: 334  ESSTTSSGASTATNSESSTTSSGASTATNSGSSTT-SSGTSTATNSESSTVSSGASTATT 392

Query: 1275 YKSSNASE---TEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQPNYHTKL 1331
             +SS  S    T  N+  +   S +    ++   +T + AN+  N  +S TS  +    L
Sbjct: 393  SESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAAL 452

Query: 1332 KKAWLTRHS 1340
                 T HS
Sbjct: 453  TGMHTTSHS 461



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 65/285 (22%), Positives = 123/285 (43%), Gaps = 17/285 (5%)

Query: 1141 NSDSVHTKSEKNFQAVSQGSVPSS-VMSAVNTMCNTKTDVITSA--ADTTSVSSWGGSEV 1197
            NS+S  T S  +    S+ S PSS   +A N+  +T +   ++A  +D+++ SS   +  
Sbjct: 107  NSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTAT 166

Query: 1198 ISSLSNTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGT 1257
             S  S T   ++++    S +VS   +     + STT+  + AS+ T S  + +S  +GT
Sbjct: 167  NSESSTTSSGASTATNSESSTVSSRASTATNSESSTTS--SGASTATNSESRTTSNGAGT 224

Query: 1258 TDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNG 1317
                   +     + A   +++ S T  +     T S S    S    +T +++++V +G
Sbjct: 225  AT---NSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSG 281

Query: 1318 QASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQN 1377
             ++ T+  +  T    A    +SE    ++    + NS S      + +  AST+++ ++
Sbjct: 282  ISTVTNSES-STPSSGANTATNSESSTTSSGANTATNSDSS-----TTSSGASTATNSES 335

Query: 1378 SVDSKIIVDKYVKDDKVNRRKAKRTYESGS---ESGDSDESESKS 1419
            S  S         +       A     SGS    SG S  + S+S
Sbjct: 336  STTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSES 380



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 34/139 (24%), Positives = 61/139 (43%), Gaps = 3/139 (2%)

Query: 1141 NSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAA---DTTSVSSWGGSEV 1197
            NS+S  T S  +    S+ S  SS  S      ++ T   TS A   ++++VSS   +  
Sbjct: 332  NSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTAT 391

Query: 1198 ISSLSNTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGT 1257
             S  S T   ++++    S +VS   +     + STT+     ++ +GS V  +   +  
Sbjct: 392  TSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAA 451

Query: 1258 TDFIHLKKHKAALAAAQYK 1276
               +H   H A+ A ++ K
Sbjct: 452  LTGMHTTSHSASTAVSEAK 470


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 60/298 (20%), Positives = 117/298 (39%), Gaps = 19/298 (6%)

Query: 29  HSLLKGENIGITSRRRSRANQNVNAVHSHYTRAQANSPRPAMNSQAAVPKQNTHQQQQQR 88
           H+  K  +   +  RR R+     +   + +R++    R + +      K    ++ + R
Sbjct: 311 HTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSR 370

Query: 89  SIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKPEEDEKKLNMKRL 148
           S   +KRK +   I ++E++KE+  D     E  K + K    K R   +D  K   K  
Sbjct: 371 SHSRDKRKDTREKIKEKERVKEK--DREKEREREKEREK---EKERGKNKDRDKEREKDR 425

Query: 149 RTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKPHNNEKAGEETL 208
             D   D     + E+   R  +   EQ  E E + K+ SK   E+ K     +    + 
Sbjct: 426 EKDKEKDREREREKEHEKDRDKEKEKEQDKEKE-REKDRSKEIDEKRKKDKKSRTPPRSY 484

Query: 209 KNSQPPWDQIQEDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLPQECNMDK 268
             S+      +E ++       +S  T   + +   SS   +    N  D   ++   ++
Sbjct: 485 NASRRSRSSSRERRRRRSRSSSRSPRT--SKTIKRKSSRSPSPRSRNKKD---KKREKER 539

Query: 269 THTMELLPKEKFVSRPPTPKCVIDITNDTNLEKVAQENSSTFGLQTLQKMDPNVSDSK 326
            H  E   +E+  S   +       +ND + ++  ++NS++   +   K +P+ S SK
Sbjct: 540 DHISERRERERSTSMRKS-------SNDRDGKEKLEKNSTSLKEKEHNK-EPDSSVSK 589



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 35/165 (21%), Positives = 69/165 (41%), Gaps = 14/165 (8%)

Query: 86  QQRSIRPNKRKG----------SDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRK 135
           +  S + N+RKG          S SS     + K  +  + SR  N   +++     RR+
Sbjct: 294 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHN---RSRSRQKDRRR 350

Query: 136 PEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEG 195
            +   KK +  R R  + S  S S D     +  I      K ++  K +   K   +E 
Sbjct: 351 SKSPHKKRSKSRERRKSRSR-SHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEK 409

Query: 196 KPHNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQED 240
           +   N+   +E  K+ +   ++ +E ++ +E EK +  + + ++D
Sbjct: 410 ERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD 454



 Score = 34.7 bits (78), Expect = 1.1
 Identities = 30/127 (23%), Positives = 59/127 (46%), Gaps = 8/127 (6%)

Query: 77  PKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKP 136
           P+     ++ + S R  +R+ S SS       K  K    SR  +P+ +NK   +K+R+ 
Sbjct: 481 PRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKS-SRSPSPRSRNKK--DKKREK 537

Query: 137 EEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSS--EQKPENELKNKNTSKINGEE 194
           E D      +R R+   +   +SS+  +  +++  NS+  ++K  N+  + + SK   ++
Sbjct: 538 ERDHISERRERERS---TSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDK 594

Query: 195 GKPHNNE 201
             P   E
Sbjct: 595 DAPRTEE 601



 Score = 33.1 bits (74), Expect = 3.2
 Identities = 25/166 (15%), Positives = 65/166 (39%), Gaps = 3/166 (1%)

Query: 78  KQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKPE 137
           + +T  + +  S   ++RK S S        +        R      K +    +RRK  
Sbjct: 309 RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSR 368

Query: 138 EDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPE---NELKNKNTSKINGEE 194
                 + ++   + + +     + +   +R  +   E++ E   N+ ++K   K   ++
Sbjct: 369 SRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKD 428

Query: 195 GKPHNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQED 240
            +     +  +E  K+     ++ Q+ +K  E ++ K +D + ++D
Sbjct: 429 KEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKD 474



 Score = 32.3 bits (72), Expect = 5.5
 Identities = 30/144 (20%), Positives = 63/144 (43%), Gaps = 3/144 (2%)

Query: 1337 TRHSEEDKNTNKMENSGNSVS-EIIKPCSVNLIASTSSDIQNSVDSKIIVDKYVKDDKVN 1395
            +R  ++D+  +K  +   S S E  K  S +       D +  +  K  V +  ++ +  
Sbjct: 341  SRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERE 400

Query: 1396 RRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQK-RKGEIEEDLKPNGV 1454
            R K +   +   ++ D D+   K  ++ K + +   ++K+++  + ++ E E+D +    
Sbjct: 401  REKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKERE 460

Query: 1455 LSRSAKERSKLKLQSNSNTGIPRS 1478
              RS +   K K    S T  PRS
Sbjct: 461  KDRSKEIDEKRKKDKKSRTP-PRS 483


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 60/298 (20%), Positives = 117/298 (39%), Gaps = 19/298 (6%)

Query: 29  HSLLKGENIGITSRRRSRANQNVNAVHSHYTRAQANSPRPAMNSQAAVPKQNTHQQQQQR 88
           H+  K  +   +  RR R+     +   + +R++    R + +      K    ++ + R
Sbjct: 195 HTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSR 254

Query: 89  SIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKPEEDEKKLNMKRL 148
           S   +KRK +   I ++E++KE+  D     E  K + K    K R   +D  K   K  
Sbjct: 255 SHSRDKRKDTREKIKEKERVKEK--DREKEREREKEREK---EKERGKNKDRDKEREKDR 309

Query: 149 RTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKPHNNEKAGEETL 208
             D   D     + E+   R  +   EQ  E E + K+ SK   E+ K     +    + 
Sbjct: 310 EKDKEKDREREREKEHEKDRDKEKEKEQDKEKE-REKDRSKEIDEKRKKDKKSRTPPRSY 368

Query: 209 KNSQPPWDQIQEDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLPQECNMDK 268
             S+      +E ++       +S  T   + +   SS   +    N  D   ++   ++
Sbjct: 369 NASRRSRSSSRERRRRRSRSSSRSPRT--SKTIKRKSSRSPSPRSRNKKD---KKREKER 423

Query: 269 THTMELLPKEKFVSRPPTPKCVIDITNDTNLEKVAQENSSTFGLQTLQKMDPNVSDSK 326
            H  E   +E+  S   +       +ND + ++  ++NS++   +   K +P+ S SK
Sbjct: 424 DHISERRERERSTSMRKS-------SNDRDGKEKLEKNSTSLKEKEHNK-EPDSSVSK 473



 Score = 38.9 bits (89), Expect = 0.059
 Identities = 35/165 (21%), Positives = 69/165 (41%), Gaps = 14/165 (8%)

Query: 86  QQRSIRPNKRKG----------SDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRK 135
           +  S + N+RKG          S SS     + K  +  + SR  N   +++     RR+
Sbjct: 178 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHN---RSRSRQKDRRR 234

Query: 136 PEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEG 195
            +   KK +  R R  + S  S S D     +  I      K ++  K +   K   +E 
Sbjct: 235 SKSPHKKRSKSRERRKSRSR-SHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEK 293

Query: 196 KPHNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQED 240
           +   N+   +E  K+ +   ++ +E ++ +E EK +  + + ++D
Sbjct: 294 ERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD 338



 Score = 34.7 bits (78), Expect = 1.1
 Identities = 30/127 (23%), Positives = 59/127 (46%), Gaps = 8/127 (6%)

Query: 77  PKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKP 136
           P+     ++ + S R  +R+ S SS       K  K    SR  +P+ +NK   +K+R+ 
Sbjct: 365 PRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKS-SRSPSPRSRNKK--DKKREK 421

Query: 137 EEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSS--EQKPENELKNKNTSKINGEE 194
           E D      +R R+   +   +SS+  +  +++  NS+  ++K  N+  + + SK   ++
Sbjct: 422 ERDHISERRERERS---TSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDK 478

Query: 195 GKPHNNE 201
             P   E
Sbjct: 479 DAPRTEE 485



 Score = 33.1 bits (74), Expect = 3.2
 Identities = 25/166 (15%), Positives = 65/166 (39%), Gaps = 3/166 (1%)

Query: 78  KQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKPE 137
           + +T  + +  S   ++RK S S        +        R      K +    +RRK  
Sbjct: 193 RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSR 252

Query: 138 EDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPE---NELKNKNTSKINGEE 194
                 + ++   + + +     + +   +R  +   E++ E   N+ ++K   K   ++
Sbjct: 253 SRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKD 312

Query: 195 GKPHNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQED 240
            +     +  +E  K+     ++ Q+ +K  E ++ K +D + ++D
Sbjct: 313 KEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKD 358



 Score = 32.3 bits (72), Expect = 5.5
 Identities = 30/144 (20%), Positives = 63/144 (43%), Gaps = 3/144 (2%)

Query: 1337 TRHSEEDKNTNKMENSGNSVS-EIIKPCSVNLIASTSSDIQNSVDSKIIVDKYVKDDKVN 1395
            +R  ++D+  +K  +   S S E  K  S +       D +  +  K  V +  ++ +  
Sbjct: 225  SRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERE 284

Query: 1396 RRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQK-RKGEIEEDLKPNGV 1454
            R K +   +   ++ D D+   K  ++ K + +   ++K+++  + ++ E E+D +    
Sbjct: 285  REKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKERE 344

Query: 1455 LSRSAKERSKLKLQSNSNTGIPRS 1478
              RS +   K K    S T  PRS
Sbjct: 345  KDRSKEIDEKRKKDKKSRTP-PRS 367


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.126    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,591,849
Number of Sequences: 37866
Number of extensions: 4757899
Number of successful extensions: 22889
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 106
Number of HSP's successfully gapped in prelim test: 677
Number of HSP's that attempted gapping in prelim test: 17997
Number of HSP's gapped (non-prelim): 4881
length of query: 2303
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2185
effective length of database: 13,779,330
effective search space: 30107836050
effective search space used: 30107836050
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.