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Search of human proteins with 67188443
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|67188443 CD276 antigen isoform a [Homo sapiens]
(534 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|67188443 CD276 antigen isoform a [Homo sapiens] 1072 0.0
gi|13376852 CD276 antigen isoform b [Homo sapiens] 578 e-165
gi|9624969 butyrophilin-like 2 [Homo sapiens] 150 4e-36
gi|7661534 CD274 molecule [Homo sapiens] 119 5e-27
gi|27477039 inducible T-cell co-stimulator ligand [Homo sapiens] 99 1e-20
gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens] 99 1e-20
gi|34932496 butyrophilin, subfamily 3, member A2 precursor [Homo... 97 3e-20
gi|5901908 butyrophilin, subfamily 3, member A3 isoform a [Homo ... 95 2e-19
gi|99028881 V-set domain containing T cell activation inhibitor ... 91 3e-18
gi|37221189 butyrophilin, subfamily 3, member A1 isoform b [Homo... 89 1e-17
gi|222418660 butyrophilin, subfamily 3, member A1 isoform d [Hom... 89 1e-17
gi|37595558 butyrophilin, subfamily 3, member A1 isoform a [Homo... 89 1e-17
gi|229577039 butyrophilin-like 8 isoform 4 precursor [Homo sapiens] 88 2e-17
gi|94957742 butyrophilin-like 8 isoform 2 precursor [Homo sapiens] 88 2e-17
gi|13376271 butyrophilin-like 8 isoform 1 precursor [Homo sapiens] 88 2e-17
gi|60460897 butyrophilin-like 9 [Homo sapiens] 87 5e-17
gi|37574628 butyrophilin, subfamily 3, member A3 isoform b [Homo... 86 1e-16
gi|5921461 butyrophilin, subfamily 2, member A1 isoform 1 precur... 85 1e-16
gi|17975772 butyrophilin, subfamily 2, member A1 isoform 2 precu... 85 1e-16
gi|5901964 HERV-H LTR-associating 2 [Homo sapiens] 76 9e-14
gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo ... 75 1e-13
gi|190014605 programmed cell death 1 ligand 2 [Homo sapiens] 71 2e-12
gi|118572606 hemicentin 1 [Homo sapiens] 70 4e-12
gi|110349719 titin isoform N2-A [Homo sapiens] 70 6e-12
gi|56788393 myelin oligodendrocyte glycoprotein isoform beta5 pr... 70 6e-12
gi|56788391 myelin oligodendrocyte glycoprotein isoform beta2 pr... 70 6e-12
gi|56788389 myelin oligodendrocyte glycoprotein isoform alpha3 p... 70 6e-12
gi|56788387 myelin oligodendrocyte glycoprotein isoform beta3 pr... 70 6e-12
gi|56788385 myelin oligodendrocyte glycoprotein isoform beta1 pr... 70 6e-12
gi|56788383 myelin oligodendrocyte glycoprotein isoform alpha2 p... 70 6e-12
>gi|67188443 CD276 antigen isoform a [Homo sapiens]
Length = 534
Score = 1072 bits (2772), Expect = 0.0
Identities = 534/534 (100%), Positives = 534/534 (100%)
Query: 1 MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSL 60
MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSL
Sbjct: 1 MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSL 60
Query: 61 AQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSF 120
AQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSF
Sbjct: 61 AQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSF 120
Query: 121 TCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQD 180
TCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQD
Sbjct: 121 TCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQD 180
Query: 181 GQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTITPQ 240
GQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTITPQ
Sbjct: 181 GQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTITPQ 240
Query: 241 RSPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEG 300
RSPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEG
Sbjct: 241 RSPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEG 300
Query: 301 RDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPY 360
RDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPY
Sbjct: 301 RDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPY 360
Query: 361 SKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLF 420
SKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLF
Sbjct: 361 SKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLF 420
Query: 421 DVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIAL 480
DVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIAL
Sbjct: 421 DVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIAL 480
Query: 481 LVALAFVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLKHSDSKEDDGQEIA 534
LVALAFVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLKHSDSKEDDGQEIA
Sbjct: 481 LVALAFVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLKHSDSKEDDGQEIA 534
>gi|13376852 CD276 antigen isoform b [Homo sapiens]
Length = 316
Score = 578 bits (1489), Expect = e-165
Identities = 287/291 (98%), Positives = 289/291 (99%)
Query: 244 TGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQ 303
TGA+EVQVPEDPVVALVGTDATL CSFSPEPGFSLAQLNLIWQLTDTKQLVHSF EG+DQ
Sbjct: 26 TGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQ 85
Query: 304 GSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKP 363
GSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKP
Sbjct: 86 GSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKP 145
Query: 364 SMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVH 423
SMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVH
Sbjct: 146 SMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVH 205
Query: 424 SVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIALLVA 483
SVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIALLVA
Sbjct: 206 SVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIALLVA 265
Query: 484 LAFVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLKHSDSKEDDGQEIA 534
LAFVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLKHSDSKEDDGQEIA
Sbjct: 266 LAFVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLKHSDSKEDDGQEIA 316
Score = 478 bits (1230), Expect = e-135
Identities = 240/253 (94%), Positives = 243/253 (96%), Gaps = 2/253 (0%)
Query: 1 MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSL 60
MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSL
Sbjct: 1 MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSL 60
Query: 61 AQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSF 120
AQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSF
Sbjct: 61 AQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSF 120
Query: 121 TCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQD 180
TCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSY+GYPEAEVFWQD
Sbjct: 121 TCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQD 180
Query: 181 GQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTIT-- 238
GQGVPLTGNVTTSQMANEQGLFDVHS+LRVVLGANGTYSCLVRNPVLQQDAH SVTIT
Sbjct: 181 GQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQ 240
Query: 239 PQRSPTGAVEVQV 251
P P A+ V V
Sbjct: 241 PMTFPPEALWVTV 253
>gi|9624969 butyrophilin-like 2 [Homo sapiens]
Length = 455
Score = 150 bits (378), Expect = 4e-36
Identities = 114/439 (25%), Positives = 214/439 (48%), Gaps = 33/439 (7%)
Query: 34 PEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQD----QGSAY 89
P P++A VG DA L C P+ + + + W ++ V +G + Q Y
Sbjct: 34 PAHPILAGVGEDALLTCQLLPKR--TTMHVEVRWYRSEPSTPVFVHRDGVEVTEMQMEEY 91
Query: 90 ANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAPYSKPSMT 148
+ +A+GN +L++ ++ +D G + C ++ G ++ L+VA S PS+
Sbjct: 92 RGWVEWIENGIAKGNVALKIHNIQPSDNGQYWCHFQDGNYCGETSLLLKVAGLGSAPSIH 151
Query: 149 LEPNKDLRPGDT-VTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSI 207
+E PG++ V + C++ +PE +V+W+D +G L V+ ++ ++ GLF +
Sbjct: 152 MEG-----PGESGVQLVCTARGWFPEPQVYWEDIRGEKLLA-VSEHRIQDKDGLFYAEAT 205
Query: 208 LRVVLGANGTYSCLVRNPVLQQDAHSSVTITPQRSPT--GAVEVQVPEDPVVALVGTDAT 265
L V + + SCLV NPVL ++ S +++ P++ T +++V P P++ VG D
Sbjct: 206 LVVRNASAESVSCLVHNPVLTEEKGSVISL-PEKLQTELASLKVNGPSQPILVRVGEDIQ 264
Query: 266 LRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGR----DQGSAYANRTALFPDLLAQG 321
L C SP+ + + + W + VH + +G +Q + Y RT L D + +G
Sbjct: 265 LTCYLSPKA--NAQSMEVRWDRSHRYPAVHVYMDGDHVAGEQMAEYRGRTVLVSDAIDEG 322
Query: 322 NASLRLQRVRVADEGSFTCFVSIRD-FGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVT 380
+L++ R +D+G + C D + A++ L+V + S P +T+E +D +
Sbjct: 323 RLTLQILSARPSDDGQYRCLFEKDDVYQEASLDLKVVSLGSSPLITVEGQED----GEMQ 378
Query: 381 ITCSSYRGYPEAEVFWQD--GQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSC 438
CSS +P+ V W+D G+ +P + T GLF V ++LRV + +C
Sbjct: 379 PMCSSDGWFPQPHVPWRDMEGKTIPSSSQALTQ---GSHGLFHVQTLLRVTNISAVDVTC 435
Query: 439 LVRNPVLQQDAHGSVTITG 457
+ P L ++ + +++G
Sbjct: 436 SISIPFLGEEKIATFSLSG 454
Score = 80.1 bits (196), Expect = 5e-15
Identities = 56/218 (25%), Positives = 104/218 (47%), Gaps = 16/218 (7%)
Query: 28 ALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQ---- 83
+L+V P P++ VG D L C SP+ + + + W + VH + +G
Sbjct: 245 SLKVNGPSQPILVRVGEDIQLTCYLSPKA--NAQSMEVRWDRSHRYPAVHVYMDGDHVAG 302
Query: 84 DQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRD-FGSAAVSLQVAAPY 142
+Q + Y RT L D + +G +L++ R +D+G + C D + A++ L+V +
Sbjct: 303 EQMAEYRGRTVLVSDAIDEGRLTLQILSARPSDDGQYRCLFEKDDVYQEASLDLKVVSLG 362
Query: 143 SKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQD--GQGVPLTGNVTTSQMANEQG 200
S P +T+E +D + CSS +P+ V W+D G+ +P + T G
Sbjct: 363 SSPLITVEGQED----GEMQPMCSSDGWFPQPHVPWRDMEGKTIPSSSQALTQ---GSHG 415
Query: 201 LFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTIT 238
LF V ++LRV + +C + P L ++ ++ +++
Sbjct: 416 LFHVQTLLRVTNISAVDVTCSISIPFLGEEKIATFSLS 453
>gi|7661534 CD274 molecule [Homo sapiens]
Length = 290
Score = 119 bits (299), Expect = 5e-27
Identities = 81/270 (30%), Positives = 129/270 (47%), Gaps = 13/270 (4%)
Query: 246 AVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTK--QLVHSFTEGRDQ 303
A V VP+D V G++ T+ C F E LA L + W++ D Q VH + + Q
Sbjct: 18 AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQ 77
Query: 304 GSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKP 363
S+Y R L D L+ GNA+L++ V++ D G + C +S ++++V APY+K
Sbjct: 78 HSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYNKI 137
Query: 364 SMTLEPNKDLRPGDTVT----ITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGL 419
N+ + D VT +TC + GYP+AEV W L+G TT+ E+ L
Sbjct: 138 ------NQRILVVDPVTSEHELTCQA-EGYPKAEVIWTSSDHQVLSGKTTTTNSKREEKL 190
Query: 420 FDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIA 479
F+V S LR+ N + C R +++ + I P+ PP V L L+
Sbjct: 191 FNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTHLVILGAILLC 250
Query: 480 LLVALAFVCWRKIKQSCEEENAGAEDQDGE 509
L VAL F+ + + + + G +D + +
Sbjct: 251 LGVALTFIFRLRKGRMMDVKKCGIQDTNSK 280
Score = 106 bits (264), Expect = 6e-23
Identities = 70/222 (31%), Positives = 112/222 (50%), Gaps = 14/222 (6%)
Query: 25 LTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTK--QLVHSFAEG 82
L A V VP+D V G++ T+ C F E LA L + W++ D Q VH +
Sbjct: 15 LLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDL 74
Query: 83 QDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPY 142
+ Q S+Y R L D L+ GNA+L++ V++ D G + C +S ++++V APY
Sbjct: 75 KVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPY 134
Query: 143 SKPSMTLEPNKDLRPGDTVT----ITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANE 198
+K N+ + D VT +TC + +GYP+AEV W L+G TT+ E
Sbjct: 135 NK------INQRILVVDPVTSEHELTCQA-EGYPKAEVIWTSSDHQVLSGKTTTTNSKRE 187
Query: 199 QGLFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTITPQ 240
+ LF+V S LR+ N + C R + ++ H++ + P+
Sbjct: 188 EKLFNVTSTLRINTTTNEIFYCTFRR-LDPEENHTAELVIPE 228
>gi|27477039 inducible T-cell co-stimulator ligand [Homo sapiens]
Length = 302
Score = 98.6 bits (244), Expect = 1e-20
Identities = 80/266 (30%), Positives = 119/266 (44%), Gaps = 33/266 (12%)
Query: 4 RRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQL 63
R GSPG L F L +L E V A+VG+D L C+ F L +
Sbjct: 2 RLGSPG-----------LLFLLFSSLRADTQEKEVRAMVGSDVELSCACPEGSRFDLNDV 50
Query: 64 NLIWQLTDTKQLV------HSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADE 117
+ WQ +++K +V +S E D S Y NR + P + +G+ SLRL V DE
Sbjct: 51 YVYWQTSESKTVVTYHIPQNSSLENVD--SRYRNRALMSPAGMLRGDFSLRLFNVTPQDE 108
Query: 118 GSFTCFVSIRDFG-----SAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYQGYP 172
F C V + G S V+L VAA +S P ++ + D +T TC+S GYP
Sbjct: 109 QKFHCLVLSQSLGFQEVLSVEVTLHVAANFSVPVVSAPHSPS---QDELTFTCTSINGYP 165
Query: 173 EAEVFWQDGQGVPLTGNVTTSQ--MANEQGLFDVHSILRVVLGANGTYSCLVRNPVLQQD 230
V+W + L + N +GL+DV S+LR+ + C + N +LQQ
Sbjct: 166 RPNVYWINKTDNSLLDQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQ- 224
Query: 231 AHSSVTITPQRSPTGAVEVQVPEDPV 256
++T+ Q ++ E+PV
Sbjct: 225 ---NLTVGSQTGNDIGERDKITENPV 247
Score = 97.8 bits (242), Expect = 2e-20
Identities = 80/268 (29%), Positives = 123/268 (45%), Gaps = 30/268 (11%)
Query: 246 AVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLV------HSFTE 299
++ E V A+VG+D L C+ F L + + WQ +++K +V +S E
Sbjct: 15 SLRADTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTSESKTVVTYHIPQNSSLE 74
Query: 300 GRDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFG-----SAAVSL 354
D S Y NR + P + +G+ SLRL V DE F C V + G S V+L
Sbjct: 75 NVD--SRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSLGFQEVLSVEVTL 132
Query: 355 QVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQ-- 412
VAA +S P ++ + D +T TC+S GYP V+W + L +
Sbjct: 133 HVAANFSVPVVSAPHSPS---QDELTFTCTSINGYPRPNVYWINKTDNSLLDQALQNDTV 189
Query: 413 MANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQD-AHGSVT---------ITGQPMTF 462
N +GL+DV SVLR+ + C + N +LQQ+ GS T IT P++
Sbjct: 190 FLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERDKITENPVST 249
Query: 463 PPE--ALWVTVGLSVCLIALLVALAFVC 488
+ A W + + L+ + VA+ +VC
Sbjct: 250 GEKNAATWSILAVLCLLVVVAVAIGWVC 277
>gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]
Length = 526
Score = 98.6 bits (244), Expect = 1e-20
Identities = 75/249 (30%), Positives = 125/249 (50%), Gaps = 22/249 (8%)
Query: 252 PEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQGSA----Y 307
P +P++A+VG DA L C SP S L L W V +GR+Q + Y
Sbjct: 34 PPEPILAVVGEDAELPCRLSPNA--SAEHLELRWFRKKVSPAVLVHRDGREQEAEQMPEY 91
Query: 308 ANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGS---AAVSLQVAAPYSKPS 364
R L D +A+G +LR++ VRV+D+G +TCF R+ GS A V L+VAA S P
Sbjct: 92 RGRATLVQDGIAKGRVALRIRGVRVSDDGEYTCF--FREDGSYEEALVHLKVAALGSDPH 149
Query: 365 MTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHS 424
++++ ++ + + C+S YPE +V W+ +G + + S+ +E+GLF V +
Sbjct: 150 ISMQ----VQENGEICLECTSVGWYPEPQVQWRTSKGEKFP-STSESRNPDEEGLFTVAA 204
Query: 425 VLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIA---LL 481
+ + + SC ++N +L Q+ ++I + P W+ V ++V L+ L
Sbjct: 205 SVIIRDTSAKNVSCYIQNLLLGQEKKVEISIPAS--SLPRLTPWI-VAVAVILMVLGLLT 261
Query: 482 VALAFVCWR 490
+ F WR
Sbjct: 262 IGSIFFTWR 270
Score = 94.4 bits (233), Expect = 2e-19
Identities = 65/215 (30%), Positives = 109/215 (50%), Gaps = 12/215 (5%)
Query: 34 PEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQD--QGSAYAN 91
P +P++A+VG DA L C SP +L + LVH Q+ Q Y
Sbjct: 34 PPEPILAVVGEDAELPCRLSPNASAEHLELRWFRKKVSPAVLVHRDGREQEAEQMPEYRG 93
Query: 92 RTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGS---AAVSLQVAAPYSKPSMT 148
R L D +A+G +LR++ VRV+D+G +TCF R+ GS A V L+VAA S P ++
Sbjct: 94 RATLVQDGIAKGRVALRIRGVRVSDDGEYTCF--FREDGSYEEALVHLKVAALGSDPHIS 151
Query: 149 LEPNKDLRPGDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSIL 208
++ ++ + + C+S YPE +V W+ +G + + S+ +E+GLF V + +
Sbjct: 152 MQ----VQENGEICLECTSVGWYPEPQVQWRTSKGEKFP-STSESRNPDEEGLFTVAASV 206
Query: 209 RVVLGANGTYSCLVRNPVLQQDAHSSVTITPQRSP 243
+ + SC ++N +L Q+ ++I P
Sbjct: 207 IIRDTSAKNVSCYIQNLLLGQEKKVEISIPASSLP 241
>gi|34932496 butyrophilin, subfamily 3, member A2 precursor [Homo
sapiens]
Length = 334
Score = 97.4 bits (241), Expect = 3e-20
Identities = 70/269 (26%), Positives = 127/269 (47%), Gaps = 13/269 (4%)
Query: 232 HSSVTITPQRSPTGA-VEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDT 290
H S+ + +P A V P P++A+VG DA L C P S + L W +
Sbjct: 15 HVSLLLVQLLTPCSAQFSVLGPSGPILAMVGEDADLPCHLFPT--MSAETMELKWVSSSL 72
Query: 291 KQLVHSFTEGRD----QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRD 346
+Q+V+ + +G++ Q + Y RT++ D + G A+LR+ V +D G + C+ D
Sbjct: 73 RQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGD 132
Query: 347 F-GSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLT 405
F A V L+VAA S + ++ +D + + C S YP+ ++ W + +G +
Sbjct: 133 FYEKALVELKVAALGSNLHVEVKGYED----GGIHLECRSTGWYPQPQIQWSNAKGENIP 188
Query: 406 GNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPE 465
V +A+ GL++V + + + G+ SC++RN +L + S++I
Sbjct: 189 A-VEAPVVADGVGLYEVAASVIMRGGSGEGVSCIIRNSLLGLEKTASISIADPFFRSAQP 247
Query: 466 ALWVTVGLSVCLIALLVALAFVCWRKIKQ 494
+ G L+ LL ++ WR+ K+
Sbjct: 248 WIAALAGTLPILLLLLAGASYFLWRQQKE 276
Score = 92.4 bits (228), Expect = 9e-19
Identities = 64/233 (27%), Positives = 115/233 (49%), Gaps = 12/233 (5%)
Query: 10 MGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQL 69
+ HV L L + V P P++A+VG DA L C P S + L W
Sbjct: 12 LNFHVSLLLVQLLTPCSAQFSVLGPSGPILAMVGEDADLPCHLFPT--MSAETMELKWVS 69
Query: 70 TDTKQLVHSFAEGQD----QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVS 125
+ +Q+V+ +A+G++ Q + Y RT++ D + G A+LR+ V +D G + C+
Sbjct: 70 SSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQ 129
Query: 126 IRDF-GSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQDGQGV 184
DF A V L+VAA S + ++ +D + + C S YP+ ++ W + +G
Sbjct: 130 DGDFYEKALVELKVAALGSNLHVEVKGYED----GGIHLECRSTGWYPQPQIQWSNAKGE 185
Query: 185 PLTGNVTTSQMANEQGLFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTI 237
+ V +A+ GL++V + + + G+ SC++RN +L + +S++I
Sbjct: 186 NIPA-VEAPVVADGVGLYEVAASVIMRGGSGEGVSCIIRNSLLGLEKTASISI 237
>gi|5901908 butyrophilin, subfamily 3, member A3 isoform a [Homo
sapiens]
Length = 584
Score = 94.7 bits (234), Expect = 2e-19
Identities = 71/271 (26%), Positives = 126/271 (46%), Gaps = 17/271 (6%)
Query: 232 HSSVTITPQRSPTGA-VEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDT 290
H S+ + +P A V P P++A+VG DA L C P S + L W +
Sbjct: 15 HVSLFLVQLLTPCSAQFSVLGPSGPILAMVGEDADLPCHLFPT--MSAETMELRWVSSSL 72
Query: 291 KQLVHSFTEGRD----QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRD 346
+Q+V+ + +G++ Q + Y RT++ D + G A+LR+ V +D G + C+ D
Sbjct: 73 RQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGD 132
Query: 347 F-GSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQD--GQGVP 403
F A V L+VAA S + ++ +D + + C S YP+ ++ W D G+ +P
Sbjct: 133 FYEKALVELKVAALGSDLHIEVKGYED----GGIHLECRSTGWYPQPQIKWSDTKGENIP 188
Query: 404 LTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFP 463
V +A+ GL+ V + + + + G SC++RN +L + S++I
Sbjct: 189 A---VEAPVVADGVGLYAVAASVIMRGSSGGGVSCIIRNSLLGLEKTASISIADPFFRSA 245
Query: 464 PEALWVTVGLSVCLIALLVALAFVCWRKIKQ 494
+ G + LL ++ WR+ K+
Sbjct: 246 QPWIAALAGTLPISLLLLAGASYFLWRQQKE 276
Score = 92.0 bits (227), Expect = 1e-18
Identities = 66/235 (28%), Positives = 115/235 (48%), Gaps = 16/235 (6%)
Query: 10 MGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQL 69
+ HV L L + V P P++A+VG DA L C P S + L W
Sbjct: 12 LNFHVSLFLVQLLTPCSAQFSVLGPSGPILAMVGEDADLPCHLFPT--MSAETMELRWVS 69
Query: 70 TDTKQLVHSFAEGQD----QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVS 125
+ +Q+V+ +A+G++ Q + Y RT++ D + G A+LR+ V +D G + C+
Sbjct: 70 SSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQ 129
Query: 126 IRDF-GSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQD--GQ 182
DF A V L+VAA S + ++ +D + + C S YP+ ++ W D G+
Sbjct: 130 DGDFYEKALVELKVAALGSDLHIEVKGYED----GGIHLECRSTGWYPQPQIKWSDTKGE 185
Query: 183 GVPLTGNVTTSQMANEQGLFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTI 237
+P V +A+ GL+ V + + + + G SC++RN +L + +S++I
Sbjct: 186 NIPA---VEAPVVADGVGLYAVAASVIMRGSSGGGVSCIIRNSLLGLEKTASISI 237
>gi|99028881 V-set domain containing T cell activation inhibitor 1
[Homo sapiens]
Length = 282
Score = 90.5 bits (223), Expect = 3e-18
Identities = 65/205 (31%), Positives = 105/205 (51%), Gaps = 19/205 (9%)
Query: 260 VGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRD----QGSAYANRTALFP 315
+G D L C+F EP L+ + + W LVH F EG+D Q + RTA+F
Sbjct: 48 IGEDGILSCTF--EPDIKLSDIVIQWLKEGVLGLVHEFKEGKDELSEQDEMFRGRTAVFA 105
Query: 316 DLLAQGNASLRLQRVRVADEGSFTCF-VSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLR 374
D + GNASLRL+ V++ D G++ C+ ++ + G+A + + A +S P + ++ N
Sbjct: 106 DQVIVGNASLRLKNVQLTDAGTYKCYIITSKGKGNANLEYKTGA-FSMPEVNVDYN---- 160
Query: 375 PGDTVTITCSSYRGYPEAEVFW--QDGQGVPLTGNVTTS-QMANEQGLFDVHSVLRVVLG 431
+ T+ C + R +P+ V W Q QG + TS ++ +E V SVL V
Sbjct: 161 -ASSETLRCEAPRWFPQPTVVWASQVDQGANFSEVSNTSFELNSENVTMKVVSVLYNVT- 218
Query: 432 ANGTYSCLVRNPVLQQDAHGSVTIT 456
N TYSC++ N + + A G + +T
Sbjct: 219 INNTYSCMIENDIAK--ATGDIKVT 241
Score = 90.1 bits (222), Expect = 4e-18
Identities = 67/230 (29%), Positives = 111/230 (48%), Gaps = 17/230 (7%)
Query: 15 GAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQ 74
GA + F ++G + V +G D L C+F EP L+ + + W
Sbjct: 21 GAIALIIGFGISGRHSITVTTVASAGNIGEDGILSCTF--EPDIKLSDIVIQWLKEGVLG 78
Query: 75 LVHSFAEGQD----QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCF-VSIRDF 129
LVH F EG+D Q + RTA+F D + GNASLRL+ V++ D G++ C+ ++ +
Sbjct: 79 LVHEFKEGKDELSEQDEMFRGRTAVFADQVIVGNASLRLKNVQLTDAGTYKCYIITSKGK 138
Query: 130 GSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFW--QDGQGVPLT 187
G+A + + A +S P + ++ N + T+ C + + +P+ V W Q QG +
Sbjct: 139 GNANLEYKTGA-FSMPEVNVDYN-----ASSETLRCEAPRWFPQPTVVWASQVDQGANFS 192
Query: 188 GNVTTS-QMANEQGLFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVT 236
TS ++ +E V S+L V N TYSC++ N + + VT
Sbjct: 193 EVSNTSFELNSENVTMKVVSVLYNVT-INNTYSCMIENDIAKATGDIKVT 241
>gi|37221189 butyrophilin, subfamily 3, member A1 isoform b [Homo
sapiens]
Length = 352
Score = 88.6 bits (218), Expect = 1e-17
Identities = 72/280 (25%), Positives = 127/280 (45%), Gaps = 18/280 (6%)
Query: 252 PEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRD----QGSAY 307
P P++A+VG DA L C P S + L W + +Q+V+ + +G++ Q + Y
Sbjct: 36 PSGPILAMVGEDADLPCHLFPT--MSAETMELKWVSSSLRQVVNVYADGKEVEDRQSAPY 93
Query: 308 ANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAPYSKPSMT 366
RT++ D + G A+LR+ V +D G + C+ DF A V L+VAA S +
Sbjct: 94 RGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHVD 153
Query: 367 LEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVL 426
++ KD + + C S YP+ ++ W + +G + V +A+ GL+ V + +
Sbjct: 154 VKGYKD----GGIHLECRSTGWYPQPQIQWSNNKGENIP-TVEAPVVADGVGLYAVAASV 208
Query: 427 RVVLGANGT-YSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIALLVALA 485
++ G++G SC +R+ +L + S++I + G L+ LL
Sbjct: 209 -IMRGSSGEGVSCTIRSSLLGLEKTASISIADPFFRSAQRWIAALAGTLPVLLLLLGGAG 267
Query: 486 FVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLKHSDS 525
+ W Q EE+ + E E + A +K S
Sbjct: 268 YFLW----QQQEEKKTQFRKKKREQELREMAWSTMKQEQS 303
Score = 85.5 bits (210), Expect = 1e-16
Identities = 60/210 (28%), Positives = 109/210 (51%), Gaps = 14/210 (6%)
Query: 34 PEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQD----QGSAY 89
P P++A+VG DA L C P S + L W + +Q+V+ +A+G++ Q + Y
Sbjct: 36 PSGPILAMVGEDADLPCHLFPT--MSAETMELKWVSSSLRQVVNVYADGKEVEDRQSAPY 93
Query: 90 ANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAPYSKPSMT 148
RT++ D + G A+LR+ V +D G + C+ DF A V L+VAA S +
Sbjct: 94 RGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHVD 153
Query: 149 LEPNKDLRPGDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSIL 208
++ KD + + C S YP+ ++ W + +G + V +A+ GL+ V + +
Sbjct: 154 VKGYKD----GGIHLECRSTGWYPQPQIQWSNNKGENIP-TVEAPVVADGVGLYAVAASV 208
Query: 209 RVVLGANGT-YSCLVRNPVLQQDAHSSVTI 237
++ G++G SC +R+ +L + +S++I
Sbjct: 209 -IMRGSSGEGVSCTIRSSLLGLEKTASISI 237
>gi|222418660 butyrophilin, subfamily 3, member A1 isoform d [Homo
sapiens]
Length = 378
Score = 88.6 bits (218), Expect = 1e-17
Identities = 72/280 (25%), Positives = 127/280 (45%), Gaps = 18/280 (6%)
Query: 252 PEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRD----QGSAY 307
P P++A+VG DA L C P S + L W + +Q+V+ + +G++ Q + Y
Sbjct: 36 PSGPILAMVGEDADLPCHLFPT--MSAETMELKWVSSSLRQVVNVYADGKEVEDRQSAPY 93
Query: 308 ANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAPYSKPSMT 366
RT++ D + G A+LR+ V +D G + C+ DF A V L+VAA S +
Sbjct: 94 RGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHVD 153
Query: 367 LEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVL 426
++ KD + + C S YP+ ++ W + +G + V +A+ GL+ V + +
Sbjct: 154 VKGYKD----GGIHLECRSTGWYPQPQIQWSNNKGENIP-TVEAPVVADGVGLYAVAASV 208
Query: 427 RVVLGANGT-YSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIALLVALA 485
++ G++G SC +R+ +L + S++I + G L+ LL
Sbjct: 209 -IMRGSSGEGVSCTIRSSLLGLEKTASISIADPFFRSAQRWIAALAGTLPVLLLLLGGAG 267
Query: 486 FVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLKHSDS 525
+ W Q EE+ + E E + A +K S
Sbjct: 268 YFLW----QQQEEKKTQFRKKKREQELREMAWSTMKQEQS 303
Score = 85.5 bits (210), Expect = 1e-16
Identities = 60/210 (28%), Positives = 109/210 (51%), Gaps = 14/210 (6%)
Query: 34 PEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQD----QGSAY 89
P P++A+VG DA L C P S + L W + +Q+V+ +A+G++ Q + Y
Sbjct: 36 PSGPILAMVGEDADLPCHLFPT--MSAETMELKWVSSSLRQVVNVYADGKEVEDRQSAPY 93
Query: 90 ANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAPYSKPSMT 148
RT++ D + G A+LR+ V +D G + C+ DF A V L+VAA S +
Sbjct: 94 RGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHVD 153
Query: 149 LEPNKDLRPGDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSIL 208
++ KD + + C S YP+ ++ W + +G + V +A+ GL+ V + +
Sbjct: 154 VKGYKD----GGIHLECRSTGWYPQPQIQWSNNKGENIP-TVEAPVVADGVGLYAVAASV 208
Query: 209 RVVLGANGT-YSCLVRNPVLQQDAHSSVTI 237
++ G++G SC +R+ +L + +S++I
Sbjct: 209 -IMRGSSGEGVSCTIRSSLLGLEKTASISI 237
>gi|37595558 butyrophilin, subfamily 3, member A1 isoform a [Homo
sapiens]
Length = 513
Score = 88.6 bits (218), Expect = 1e-17
Identities = 72/280 (25%), Positives = 127/280 (45%), Gaps = 18/280 (6%)
Query: 252 PEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRD----QGSAY 307
P P++A+VG DA L C P S + L W + +Q+V+ + +G++ Q + Y
Sbjct: 36 PSGPILAMVGEDADLPCHLFPT--MSAETMELKWVSSSLRQVVNVYADGKEVEDRQSAPY 93
Query: 308 ANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAPYSKPSMT 366
RT++ D + G A+LR+ V +D G + C+ DF A V L+VAA S +
Sbjct: 94 RGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHVD 153
Query: 367 LEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVL 426
++ KD + + C S YP+ ++ W + +G + V +A+ GL+ V + +
Sbjct: 154 VKGYKD----GGIHLECRSTGWYPQPQIQWSNNKGENIP-TVEAPVVADGVGLYAVAASV 208
Query: 427 RVVLGANGT-YSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIALLVALA 485
++ G++G SC +R+ +L + S++I + G L+ LL
Sbjct: 209 -IMRGSSGEGVSCTIRSSLLGLEKTASISIADPFFRSAQRWIAALAGTLPVLLLLLGGAG 267
Query: 486 FVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLKHSDS 525
+ W Q EE+ + E E + A +K S
Sbjct: 268 YFLW----QQQEEKKTQFRKKKREQELREMAWSTMKQEQS 303
Score = 85.5 bits (210), Expect = 1e-16
Identities = 60/210 (28%), Positives = 109/210 (51%), Gaps = 14/210 (6%)
Query: 34 PEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQD----QGSAY 89
P P++A+VG DA L C P S + L W + +Q+V+ +A+G++ Q + Y
Sbjct: 36 PSGPILAMVGEDADLPCHLFPT--MSAETMELKWVSSSLRQVVNVYADGKEVEDRQSAPY 93
Query: 90 ANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAPYSKPSMT 148
RT++ D + G A+LR+ V +D G + C+ DF A V L+VAA S +
Sbjct: 94 RGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHVD 153
Query: 149 LEPNKDLRPGDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSIL 208
++ KD + + C S YP+ ++ W + +G + V +A+ GL+ V + +
Sbjct: 154 VKGYKD----GGIHLECRSTGWYPQPQIQWSNNKGENIP-TVEAPVVADGVGLYAVAASV 208
Query: 209 RVVLGANGT-YSCLVRNPVLQQDAHSSVTI 237
++ G++G SC +R+ +L + +S++I
Sbjct: 209 -IMRGSSGEGVSCTIRSSLLGLEKTASISI 237
>gi|229577039 butyrophilin-like 8 isoform 4 precursor [Homo sapiens]
Length = 340
Score = 87.8 bits (216), Expect = 2e-17
Identities = 67/217 (30%), Positives = 104/217 (47%), Gaps = 14/217 (6%)
Query: 26 TGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQ 85
+G +V P+ PV ALVG DA C SP+ ++ +VH + +G+DQ
Sbjct: 16 SGQWQVFGPDKPVQALVGEDAAFSCFLSPKTNAEAMEVRFF--RGQFSSVVHLYRDGKDQ 73
Query: 86 G----SAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAV-SLQVAA 140
Y RT L D +A+G SLRL+ + V D G + C +S + + A+ LQV+A
Sbjct: 74 PFMQMPQYQGRTKLVKDSIAEGRISLRLENITVLDAGLYGCRISSQSYYQKAIWELQVSA 133
Query: 141 PYSKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQG 200
S P +++ D + + C S +P W+ QG L+ + T++ + G
Sbjct: 134 LGSVPLISITGYVD----RDIQLLCQSSGWFPRPTAKWKGPQGQDLSTDSRTNR--DMHG 187
Query: 201 LFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTI 237
LFDV L V A G+ SC +R+ L ++ S V I
Sbjct: 188 LFDVEISLTVQENA-GSISCSMRHAHLSREVESRVQI 223
Score = 86.7 bits (213), Expect = 5e-17
Identities = 67/227 (29%), Positives = 108/227 (47%), Gaps = 14/227 (6%)
Query: 234 SVTITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQL 293
S+ ++ + +G +V P+ PV ALVG DA C SP+ ++ +
Sbjct: 6 SLVLSLLKLGSGQWQVFGPDKPVQALVGEDAAFSCFLSPKTNAEAMEVRFF--RGQFSSV 63
Query: 294 VHSFTEGRDQG----SAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGS 349
VH + +G+DQ Y RT L D +A+G SLRL+ + V D G + C +S + +
Sbjct: 64 VHLYRDGKDQPFMQMPQYQGRTKLVKDSIAEGRISLRLENITVLDAGLYGCRISSQSYYQ 123
Query: 350 AAV-SLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNV 408
A+ LQV+A S P +++ D + + C S +P W+ QG L+ +
Sbjct: 124 KAIWELQVSALGSVPLISITGYVD----RDIQLLCQSSGWFPRPTAKWKGPQGQDLSTDS 179
Query: 409 TTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTI 455
T++ + GLFDV L V A G+ SC +R+ L ++ V I
Sbjct: 180 RTNR--DMHGLFDVEISLTVQENA-GSISCSMRHAHLSREVESRVQI 223
>gi|94957742 butyrophilin-like 8 isoform 2 precursor [Homo sapiens]
Length = 500
Score = 87.8 bits (216), Expect = 2e-17
Identities = 67/217 (30%), Positives = 104/217 (47%), Gaps = 14/217 (6%)
Query: 26 TGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQ 85
+G +V P+ PV ALVG DA C SP+ ++ +VH + +G+DQ
Sbjct: 16 SGQWQVFGPDKPVQALVGEDAAFSCFLSPKTNAEAMEVRFF--RGQFSSVVHLYRDGKDQ 73
Query: 86 G----SAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAV-SLQVAA 140
Y RT L D +A+G SLRL+ + V D G + C +S + + A+ LQV+A
Sbjct: 74 PFMQMPQYQGRTKLVKDSIAEGRISLRLENITVLDAGLYGCRISSQSYYQKAIWELQVSA 133
Query: 141 PYSKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQG 200
S P +++ D + + C S +P W+ QG L+ + T++ + G
Sbjct: 134 LGSVPLISITGYVD----RDIQLLCQSSGWFPRPTAKWKGPQGQDLSTDSRTNR--DMHG 187
Query: 201 LFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTI 237
LFDV L V A G+ SC +R+ L ++ S V I
Sbjct: 188 LFDVEISLTVQENA-GSISCSMRHAHLSREVESRVQI 223
Score = 86.7 bits (213), Expect = 5e-17
Identities = 67/227 (29%), Positives = 108/227 (47%), Gaps = 14/227 (6%)
Query: 234 SVTITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQL 293
S+ ++ + +G +V P+ PV ALVG DA C SP+ ++ +
Sbjct: 6 SLVLSLLKLGSGQWQVFGPDKPVQALVGEDAAFSCFLSPKTNAEAMEVRFF--RGQFSSV 63
Query: 294 VHSFTEGRDQG----SAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGS 349
VH + +G+DQ Y RT L D +A+G SLRL+ + V D G + C +S + +
Sbjct: 64 VHLYRDGKDQPFMQMPQYQGRTKLVKDSIAEGRISLRLENITVLDAGLYGCRISSQSYYQ 123
Query: 350 AAV-SLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNV 408
A+ LQV+A S P +++ D + + C S +P W+ QG L+ +
Sbjct: 124 KAIWELQVSALGSVPLISITGYVD----RDIQLLCQSSGWFPRPTAKWKGPQGQDLSTDS 179
Query: 409 TTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTI 455
T++ + GLFDV L V A G+ SC +R+ L ++ V I
Sbjct: 180 RTNR--DMHGLFDVEISLTVQENA-GSISCSMRHAHLSREVESRVQI 223
>gi|13376271 butyrophilin-like 8 isoform 1 precursor [Homo sapiens]
Length = 347
Score = 87.8 bits (216), Expect = 2e-17
Identities = 67/217 (30%), Positives = 104/217 (47%), Gaps = 14/217 (6%)
Query: 26 TGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQ 85
+G +V P+ PV ALVG DA C SP+ ++ +VH + +G+DQ
Sbjct: 16 SGQWQVFGPDKPVQALVGEDAAFSCFLSPKTNAEAMEVRFF--RGQFSSVVHLYRDGKDQ 73
Query: 86 G----SAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAV-SLQVAA 140
Y RT L D +A+G SLRL+ + V D G + C +S + + A+ LQV+A
Sbjct: 74 PFMQMPQYQGRTKLVKDSIAEGRISLRLENITVLDAGLYGCRISSQSYYQKAIWELQVSA 133
Query: 141 PYSKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQG 200
S P +++ D + + C S +P W+ QG L+ + T++ + G
Sbjct: 134 LGSVPLISITGYVD----RDIQLLCQSSGWFPRPTAKWKGPQGQDLSTDSRTNR--DMHG 187
Query: 201 LFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTI 237
LFDV L V A G+ SC +R+ L ++ S V I
Sbjct: 188 LFDVEISLTVQENA-GSISCSMRHAHLSREVESRVQI 223
Score = 86.7 bits (213), Expect = 5e-17
Identities = 67/227 (29%), Positives = 108/227 (47%), Gaps = 14/227 (6%)
Query: 234 SVTITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQL 293
S+ ++ + +G +V P+ PV ALVG DA C SP+ ++ +
Sbjct: 6 SLVLSLLKLGSGQWQVFGPDKPVQALVGEDAAFSCFLSPKTNAEAMEVRFF--RGQFSSV 63
Query: 294 VHSFTEGRDQG----SAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGS 349
VH + +G+DQ Y RT L D +A+G SLRL+ + V D G + C +S + +
Sbjct: 64 VHLYRDGKDQPFMQMPQYQGRTKLVKDSIAEGRISLRLENITVLDAGLYGCRISSQSYYQ 123
Query: 350 AAV-SLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNV 408
A+ LQV+A S P +++ D + + C S +P W+ QG L+ +
Sbjct: 124 KAIWELQVSALGSVPLISITGYVD----RDIQLLCQSSGWFPRPTAKWKGPQGQDLSTDS 179
Query: 409 TTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTI 455
T++ + GLFDV L V A G+ SC +R+ L ++ V I
Sbjct: 180 RTNR--DMHGLFDVEISLTVQENA-GSISCSMRHAHLSREVESRVQI 223
>gi|60460897 butyrophilin-like 9 [Homo sapiens]
Length = 535
Score = 86.7 bits (213), Expect = 5e-17
Identities = 78/268 (29%), Positives = 128/268 (47%), Gaps = 15/268 (5%)
Query: 243 PTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRD 302
P+ V+V PE P++ALVG + C P+ Q+ + W + T +VH + E ++
Sbjct: 34 PSSEVKVLGPEYPILALVGEEVEFPCHLWPQ--LDAQQMEIRWFRSQTFNVVHLYQEQQE 91
Query: 303 ----QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTC-FVSIRDFGSAAVSLQVA 357
Q A+ NRT L D +A G+ L+L + +D+G++ C F S G A L+VA
Sbjct: 92 LPGRQMPAFRNRTKLVKDDIAYGSVVLQLHSIIPSDKGTYGCRFHSDNFSGEALWELEVA 151
Query: 358 APYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQ 417
S P ++LE K+ + + S YP+ +V W+D QG L + + + Q
Sbjct: 152 GLGSDPHLSLEGFKE----GGIQLRLRSSGWYPKPKVQWRDHQGQCLPPEF-EAIVWDAQ 206
Query: 418 GLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVC- 476
LF + + + V GA S ++N +L Q V I + P + W + ++
Sbjct: 207 DLFSLETSVVVRAGALSNVSVSIQNLLLSQKKELVVQIA--DVFVPGASAWKSAFVATLP 264
Query: 477 LIALLVALAFVCWRKIKQSCEEENAGAE 504
L+ +L ALA RK ++S E+ AE
Sbjct: 265 LLLVLAALALGVLRKQRRSREKLRKQAE 292
Score = 77.0 bits (188), Expect = 4e-14
Identities = 66/215 (30%), Positives = 104/215 (48%), Gaps = 14/215 (6%)
Query: 30 EVQV--PEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQD--- 84
EV+V PE P++ALVG + C P+ Q+ + W + T +VH + E Q+
Sbjct: 37 EVKVLGPEYPILALVGEEVEFPCHLWPQ--LDAQQMEIRWFRSQTFNVVHLYQEQQELPG 94
Query: 85 -QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTC-FVSIRDFGSAAVSLQVAAPY 142
Q A+ NRT L D +A G+ L+L + +D+G++ C F S G A L+VA
Sbjct: 95 RQMPAFRNRTKLVKDDIAYGSVVLQLHSIIPSDKGTYGCRFHSDNFSGEALWELEVAGLG 154
Query: 143 SKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLF 202
S P ++LE K+ + + S YP+ +V W+D QG L + + + Q LF
Sbjct: 155 SDPHLSLEGFKE----GGIQLRLRSSGWYPKPKVQWRDHQGQCLPPEF-EAIVWDAQDLF 209
Query: 203 DVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTI 237
+ + + V GA S ++N +L Q V I
Sbjct: 210 SLETSVVVRAGALSNVSVSIQNLLLSQKKELVVQI 244
>gi|37574628 butyrophilin, subfamily 3, member A3 isoform b [Homo
sapiens]
Length = 542
Score = 85.5 bits (210), Expect = 1e-16
Identities = 63/243 (25%), Positives = 113/243 (46%), Gaps = 16/243 (6%)
Query: 259 LVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRD----QGSAYANRTALF 314
+VG DA L C P S + L W + +Q+V+ + +G++ Q + Y RT++
Sbjct: 1 MVGEDADLPCHLFPT--MSAETMELRWVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSIL 58
Query: 315 PDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAPYSKPSMTLEPNKDL 373
D + G A+LR+ V +D G + C+ DF A V L+VAA S + ++ +D
Sbjct: 59 RDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHIEVKGYED- 117
Query: 374 RPGDTVTITCSSYRGYPEAEVFWQD--GQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLG 431
+ + C S YP+ ++ W D G+ +P V +A+ GL+ V + + +
Sbjct: 118 ---GGIHLECRSTGWYPQPQIKWSDTKGENIPA---VEAPVVADGVGLYAVAASVIMRGS 171
Query: 432 ANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIALLVALAFVCWRK 491
+ G SC++RN +L + S++I + G + LL ++ WR+
Sbjct: 172 SGGGVSCIIRNSLLGLEKTASISIADPFFRSAQPWIAALAGTLPISLLLLAGASYFLWRQ 231
Query: 492 IKQ 494
K+
Sbjct: 232 QKE 234
Score = 82.0 bits (201), Expect = 1e-15
Identities = 58/204 (28%), Positives = 103/204 (50%), Gaps = 16/204 (7%)
Query: 41 LVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQD----QGSAYANRTALF 96
+VG DA L C P S + L W + +Q+V+ +A+G++ Q + Y RT++
Sbjct: 1 MVGEDADLPCHLFPT--MSAETMELRWVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSIL 58
Query: 97 PDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAPYSKPSMTLEPNKDL 155
D + G A+LR+ V +D G + C+ DF A V L+VAA S + ++ +D
Sbjct: 59 RDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHIEVKGYED- 117
Query: 156 RPGDTVTITCSSYQGYPEAEVFWQD--GQGVPLTGNVTTSQMANEQGLFDVHSILRVVLG 213
+ + C S YP+ ++ W D G+ +P V +A+ GL+ V + + +
Sbjct: 118 ---GGIHLECRSTGWYPQPQIKWSDTKGENIPA---VEAPVVADGVGLYAVAASVIMRGS 171
Query: 214 ANGTYSCLVRNPVLQQDAHSSVTI 237
+ G SC++RN +L + +S++I
Sbjct: 172 SGGGVSCIIRNSLLGLEKTASISI 195
>gi|5921461 butyrophilin, subfamily 2, member A1 isoform 1 precursor
[Homo sapiens]
Length = 527
Score = 85.1 bits (209), Expect = 1e-16
Identities = 75/288 (26%), Positives = 132/288 (45%), Gaps = 21/288 (7%)
Query: 252 PEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGR----DQGSAY 307
P DP++A VG + TLRC SPE + + + W + V + GR +Q Y
Sbjct: 35 PTDPILATVGENTTLRCHLSPEK--NAEDMEVRWFRSQFSPAVFVYKGGRERTEEQMEEY 92
Query: 308 ANRTALFPDLLAQGNASLRLQRVRVADEGSFTC-FVSIRDFGSAAVSLQVAAPYSKPSMT 366
RT +++G+ +L + + + G++ C F R + A + L VA SKP ++
Sbjct: 93 RGRTTFVSKDISRGSVALVIHNITAQENGTYRCYFQEGRSYDEAILHLVVAGLGSKPLIS 152
Query: 367 LEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQG--VPLTGNVTTSQMANEQGLFDVHS 424
+ ++D + + C S YP+ W+D G P V+ M + GLF V +
Sbjct: 153 MRGHED----GGIRLECISRGWYPKPLTVWRDPYGGVAPALKEVS---MPDADGLFMVTT 205
Query: 425 VLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIALLVAL 484
+ + + SC + N +L Q + I P +F P V L + ++ L++ +
Sbjct: 206 AVIIRDKSVRNMSCSINNTLLGQKKESVIFI---PESFMPSVSPCAVALPIIVVILMIPI 262
Query: 485 AFVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPL-KHSDSKEDDGQ 531
A VC I + +E+ + +++ E E + AL+ L K KE++ Q
Sbjct: 263 A-VCIYWINKLQKEKKILSGEKEFERETREIALKELEKERVQKEEELQ 309
Score = 67.8 bits (164), Expect = 2e-11
Identities = 55/218 (25%), Positives = 96/218 (44%), Gaps = 16/218 (7%)
Query: 34 PEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEG----QDQGSAY 89
P DP++A VG + TL C SPE + + + W + V + G ++Q Y
Sbjct: 35 PTDPILATVGENTTLRCHLSPEK--NAEDMEVRWFRSQFSPAVFVYKGGRERTEEQMEEY 92
Query: 90 ANRTALFPDLLAQGNASLRLQRVRVADEGSFTC-FVSIRDFGSAAVSLQVAAPYSKPSMT 148
RT +++G+ +L + + + G++ C F R + A + L VA SKP ++
Sbjct: 93 RGRTTFVSKDISRGSVALVIHNITAQENGTYRCYFQEGRSYDEAILHLVVAGLGSKPLIS 152
Query: 149 LEPNKDLRPGDTVTITCSSYQGYPEAEVFWQDGQG--VPLTGNVTTSQMANEQGLFDVHS 206
+ ++D + + C S YP+ W+D G P V+ M + GLF V +
Sbjct: 153 MRGHED----GGIRLECISRGWYPKPLTVWRDPYGGVAPALKEVS---MPDADGLFMVTT 205
Query: 207 ILRVVLGANGTYSCLVRNPVLQQDAHSSVTITPQRSPT 244
+ + + SC + N +L Q S + I P+
Sbjct: 206 AVIIRDKSVRNMSCSINNTLLGQKKESVIFIPESFMPS 243
>gi|17975772 butyrophilin, subfamily 2, member A1 isoform 2
precursor [Homo sapiens]
Length = 334
Score = 85.1 bits (209), Expect = 1e-16
Identities = 75/288 (26%), Positives = 132/288 (45%), Gaps = 21/288 (7%)
Query: 252 PEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGR----DQGSAY 307
P DP++A VG + TLRC SPE + + + W + V + GR +Q Y
Sbjct: 35 PTDPILATVGENTTLRCHLSPEK--NAEDMEVRWFRSQFSPAVFVYKGGRERTEEQMEEY 92
Query: 308 ANRTALFPDLLAQGNASLRLQRVRVADEGSFTC-FVSIRDFGSAAVSLQVAAPYSKPSMT 366
RT +++G+ +L + + + G++ C F R + A + L VA SKP ++
Sbjct: 93 RGRTTFVSKDISRGSVALVIHNITAQENGTYRCYFQEGRSYDEAILHLVVAGLGSKPLIS 152
Query: 367 LEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQG--VPLTGNVTTSQMANEQGLFDVHS 424
+ ++D + + C S YP+ W+D G P V+ M + GLF V +
Sbjct: 153 MRGHED----GGIRLECISRGWYPKPLTVWRDPYGGVAPALKEVS---MPDADGLFMVTT 205
Query: 425 VLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIALLVAL 484
+ + + SC + N +L Q + I P +F P V L + ++ L++ +
Sbjct: 206 AVIIRDKSVRNMSCSINNTLLGQKKESVIFI---PESFMPSVSPCAVALPIIVVILMIPI 262
Query: 485 AFVCWRKIKQSCEEENAGAEDQDGEGEGSKTALQPL-KHSDSKEDDGQ 531
A VC I + +E+ + +++ E E + AL+ L K KE++ Q
Sbjct: 263 A-VCIYWINKLQKEKKILSGEKEFERETREIALKELEKERVQKEEELQ 309
Score = 67.8 bits (164), Expect = 2e-11
Identities = 55/218 (25%), Positives = 96/218 (44%), Gaps = 16/218 (7%)
Query: 34 PEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEG----QDQGSAY 89
P DP++A VG + TL C SPE + + + W + V + G ++Q Y
Sbjct: 35 PTDPILATVGENTTLRCHLSPEK--NAEDMEVRWFRSQFSPAVFVYKGGRERTEEQMEEY 92
Query: 90 ANRTALFPDLLAQGNASLRLQRVRVADEGSFTC-FVSIRDFGSAAVSLQVAAPYSKPSMT 148
RT +++G+ +L + + + G++ C F R + A + L VA SKP ++
Sbjct: 93 RGRTTFVSKDISRGSVALVIHNITAQENGTYRCYFQEGRSYDEAILHLVVAGLGSKPLIS 152
Query: 149 LEPNKDLRPGDTVTITCSSYQGYPEAEVFWQDGQG--VPLTGNVTTSQMANEQGLFDVHS 206
+ ++D + + C S YP+ W+D G P V+ M + GLF V +
Sbjct: 153 MRGHED----GGIRLECISRGWYPKPLTVWRDPYGGVAPALKEVS---MPDADGLFMVTT 205
Query: 207 ILRVVLGANGTYSCLVRNPVLQQDAHSSVTITPQRSPT 244
+ + + SC + N +L Q S + I P+
Sbjct: 206 AVIIRDKSVRNMSCSINNTLLGQKKESVIFIPESFMPS 243
>gi|5901964 HERV-H LTR-associating 2 [Homo sapiens]
Length = 414
Score = 75.9 bits (185), Expect = 9e-14
Identities = 86/357 (24%), Positives = 150/357 (42%), Gaps = 39/357 (10%)
Query: 23 FCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEG 82
F L + V + E V+ + D L SF E G +++ + W+ D+ + VHS+ +G
Sbjct: 24 FPLAFFIYVPMNEQIVIGRLDEDIILPSSF--ERG---SEVVIHWKYQDSYK-VHSYYKG 77
Query: 83 QD----QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQV 138
D Q YANRT+LF + + GNASL +RV + DEG +TC+V A+ +
Sbjct: 78 SDHLESQDPRYANRTSLFYNEIQNGNASLFFRRVSLLDEGIYTCYV------GTAIQVIT 131
Query: 139 AAPYSKPSMTLEPNKDLRPGDTVT-ITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMAN 197
K + L P +T + + CS YP + W+ P++ N +
Sbjct: 132 NKVVLKVGVFLTPVMKYEKRNTNSFLICSVLSVYPRPIITWK-MDNTPISEN--NMEETG 188
Query: 198 EQGLFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPVV 257
F ++S L + G+N +Y C + N +L+Q T+ + V + PV
Sbjct: 189 SLDSFSINSPLNIT-GSNSSYECTIENSLLKQTWTGRWTMKDGLHKMQSEHVSLSCQPV- 246
Query: 258 ALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDL 317
FSP F + + + T ++ + +R + +L
Sbjct: 247 ---------NDYFSPNQDFKVTWSRM---KSGTFSVLAYYLSSSQNTIINESRFSWNKEL 294
Query: 318 LAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSM-TLEPNKDL 373
+ Q + S+ L + ++D G + C +S ++ L + + +PS T NK L
Sbjct: 295 INQSDFSMNLMDLNLSDSGEYLCNISSDEY----TLLTIHTVHVEPSQETASHNKGL 347
Score = 70.5 bits (171), Expect = 4e-12
Identities = 61/214 (28%), Positives = 101/214 (47%), Gaps = 21/214 (9%)
Query: 247 VEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRD---- 302
+ V + E V+ + D L SF E G +++ + W+ D+ + VHS+ +G D
Sbjct: 30 IYVPMNEQIVIGRLDEDIILPSSF--ERG---SEVVIHWKYQDSYK-VHSYYKGSDHLES 83
Query: 303 QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSK 362
Q YANRT+LF + + GNASL +RV + DEG +TC+V A+ + K
Sbjct: 84 QDPRYANRTSLFYNEIQNGNASLFFRRVSLLDEGIYTCYVG------TAIQVITNKVVLK 137
Query: 363 PSMTLEPNKDLRPGDTVT-ITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFD 421
+ L P +T + + CS YP + W+ P++ N + F
Sbjct: 138 VGVFLTPVMKYEKRNTNSFLICSVLSVYPRPIITWKM-DNTPISEN--NMEETGSLDSFS 194
Query: 422 VHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTI 455
++S L + G+N +Y C + N +L+Q G T+
Sbjct: 195 INSPLNIT-GSNSSYECTIENSLLKQTWTGRWTM 227
>gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo
sapiens]
Length = 523
Score = 75.1 bits (183), Expect = 1e-13
Identities = 66/235 (28%), Positives = 106/235 (45%), Gaps = 19/235 (8%)
Query: 252 PEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGR----DQGSAY 307
P +P++A+VG + TLRC SPE + + + W + V + GR +Q Y
Sbjct: 39 PANPILAMVGENTTLRCHLSPEK--NAEDMEVRWFRSQFSPAVFVYKGGRERTEEQMEEY 96
Query: 308 ANRTALFPDLLAQGNASLRLQRVRVADEGSFTC-FVSIRDFGSAAVSLQVAAPYSKPSMT 366
R + +G+ +L + V + G + C F R + A + L VA SKP +
Sbjct: 97 RGRITFVSKDINRGSVALVIHNVTAQENGIYRCYFQEGRSYDEAILRLVVAGLGSKPLIE 156
Query: 367 LEPNKDLRPGDTVTITCSSYRGYPEAEVFWQD--GQGVPLTGNVTTSQMANEQGLFDVHS 424
++ +D ++ + C S YPE W+D G+ VP V+ +A+ GLF V +
Sbjct: 157 IKAQED----GSIWLECISGGWYPEPLTVWRDPYGEVVPALKEVS---IADADGLFMVTT 209
Query: 425 VLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLIA 479
+ + SC V N +L Q+ T+ P +F P A V L+V L A
Sbjct: 210 AVIIRDKYVRNVSCSVNNTLLGQEKE---TVIFIPESFMPSASPWMVALAVILTA 261
Score = 66.6 bits (161), Expect = 5e-11
Identities = 56/220 (25%), Positives = 98/220 (44%), Gaps = 16/220 (7%)
Query: 34 PEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEG----QDQGSAY 89
P +P++A+VG + TL C SPE + + + W + V + G ++Q Y
Sbjct: 39 PANPILAMVGENTTLRCHLSPEK--NAEDMEVRWFRSQFSPAVFVYKGGRERTEEQMEEY 96
Query: 90 ANRTALFPDLLAQGNASLRLQRVRVADEGSFTC-FVSIRDFGSAAVSLQVAAPYSKPSMT 148
R + +G+ +L + V + G + C F R + A + L VA SKP +
Sbjct: 97 RGRITFVSKDINRGSVALVIHNVTAQENGIYRCYFQEGRSYDEAILRLVVAGLGSKPLIE 156
Query: 149 LEPNKDLRPGDTVTITCSSYQGYPEAEVFWQD--GQGVPLTGNVTTSQMANEQGLFDVHS 206
++ +D ++ + C S YPE W+D G+ VP V+ +A+ GLF V +
Sbjct: 157 IKAQED----GSIWLECISGGWYPEPLTVWRDPYGEVVPALKEVS---IADADGLFMVTT 209
Query: 207 ILRVVLGANGTYSCLVRNPVLQQDAHSSVTITPQRSPTGA 246
+ + SC V N +L Q+ + + I P+ +
Sbjct: 210 AVIIRDKYVRNVSCSVNNTLLGQEKETVIFIPESFMPSAS 249
>gi|190014605 programmed cell death 1 ligand 2 [Homo sapiens]
Length = 273
Score = 71.2 bits (173), Expect = 2e-12
Identities = 71/256 (27%), Positives = 115/256 (44%), Gaps = 34/256 (13%)
Query: 249 VQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYA 308
V VP++ + G++ TL C+F +L + T + Q V + T S +
Sbjct: 23 VTVPKELYIIEHGSNVTLECNFDTGSHVNLGAI------TASLQKVENDT------SPHR 70
Query: 309 NRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSA----AVSLQVAAPYSKPS 364
R L + L G AS + +V+V DEG + C + +G A ++L+V A Y K +
Sbjct: 71 ERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIII---YGVAWDYKYLTLKVKASYRKIN 127
Query: 365 MTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHS 424
+ + D V +TC + GYP AEV W + VP TS +GL+ V S
Sbjct: 128 THI---LKVPETDEVELTCQA-TGYPLAEVSWPN-VSVP----ANTSHSRTPEGLYQVTS 178
Query: 425 VLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQ--PMTFPPEALWVTVGLSVCLIALLV 482
VLR+ +SC+ N +++ S+ + Q P T P L + + C+IA +
Sbjct: 179 VLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTWLLHIFI--PFCIIAFIF 236
Query: 483 ALAFVCWRKIKQSCEE 498
+ R KQ C++
Sbjct: 237 IATVIALR--KQLCQK 250
Score = 64.3 bits (155), Expect = 3e-10
Identities = 59/230 (25%), Positives = 103/230 (44%), Gaps = 32/230 (13%)
Query: 31 VQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQGSAYA 90
V VP++ + G++ TL C+F +L + S + ++ S +
Sbjct: 23 VTVPKELYIIEHGSNVTLECNFDTGSHVNLGAITA------------SLQKVENDTSPHR 70
Query: 91 NRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSA----AVSLQVAAPYSKPS 146
R L + L G AS + +V+V DEG + C + +G A ++L+V A Y K +
Sbjct: 71 ERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIII---YGVAWDYKYLTLKVKASYRKIN 127
Query: 147 MTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHS 206
+ + D V +TC + GYP AEV W + VP TS +GL+ V S
Sbjct: 128 THI---LKVPETDEVELTCQA-TGYPLAEVSWPN-VSVP----ANTSHSRTPEGLYQVTS 178
Query: 207 ILRVVLGANGTYSCLVRNPVLQQDAHSSVTI----TPQRSPTGAVEVQVP 252
+LR+ +SC+ N +++ +S+ + P+ PT + + +P
Sbjct: 179 VLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTWLLHIFIP 228
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 70.5 bits (171), Expect = 4e-12
Identities = 106/435 (24%), Positives = 165/435 (37%), Gaps = 79/435 (18%)
Query: 31 VQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQGSAYA 90
+QVP + V G A L C S NL WQ D
Sbjct: 523 IQVPNN-VTVTPGERAVLTCLI-----ISAVDYNLTWQRNDRDV---------------- 560
Query: 91 NRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAA-VSLQVAAPYSKPSMTL 149
R A + N SL L+ V+ D G + C VS SAA V L V P P +T+
Sbjct: 561 -RLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEP---PKVTV 616
Query: 150 EP-NKDLRPGDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSIL 208
P N+ G V+I CS+ GYP+ ++ W + + +M ++ LF I
Sbjct: 617 MPKNQSFTGGSEVSIMCSA-TGYPKPKIAWTVNDMFIVGSH--RYRMTSDGTLF----IK 669
Query: 209 RVVLGANGTYSCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPVVALVGTDATLRC 268
G Y CL N +S++ A ++ V + ++ +G + C
Sbjct: 670 NAAPKDAGIYGCLASNSAGTDKQNSTLRYIE------APKLMVVQSELLVALGDITVMEC 723
Query: 269 SFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQGNASLRLQ 328
S P + W D + +F + LL L++Q
Sbjct: 724 KTSGIPPPQVK-----WFKGDLELRPSTFL--------------IIDPLLGL----LKIQ 760
Query: 329 RVRVADEGSFTCFVSIRDFGSAA--VSLQVAAPYSKPSMTLEP-NKDLRPGDTVTITCSS 385
+ D G +TC V+I + G A ++L V +P P EP + + G VT+ C
Sbjct: 761 ETQDLDAGDYTC-VAINEAGRATGKITLDVGSP---PVFIQEPADVSMEIGSNVTLPCY- 815
Query: 386 YRGYPEAEVFWQDGQGVPLTG---NVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRN 442
+GYPE + W+ +P+ +V++ LF +L + GTY C N
Sbjct: 816 VQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF----ILNLWASDKGTYICEAEN 871
Query: 443 PVLQQDAHGSVTITG 457
+ + +VT+TG
Sbjct: 872 QFGKIQSETTVTVTG 886
Score = 60.1 bits (144), Expect = 5e-09
Identities = 74/359 (20%), Positives = 140/359 (38%), Gaps = 50/359 (13%)
Query: 99 LLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDL--- 155
L+ G +L++ R +V+D G +TC ++I G + + Y PS+ ++ L
Sbjct: 3012 LIVPGGRTLQIIRAKVSDGGEYTC-IAINQAGESKKKFSLTV-YVPPSIKDHDSESLSVV 3069
Query: 156 --RPGDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSILRVVLG 213
R G +V++ C S P ++++G+ +T + +A+ Q L I + +
Sbjct: 3070 NVREGTSVSLECESNAVPPPVITWYKNGR--MITESTHVEILADGQML----HIKKAEVS 3123
Query: 214 ANGTYSCLVRNPVLQQDA--HSSVTITPQRSPTGAVEVQVPE-DPVVALVGTDATLRCSF 270
G Y C N + D H +V + P ++ PE + +V + TL C
Sbjct: 3124 DTGQYVCRAINVAGRDDKNFHLNVYVPP--------SIEGPEREVIVETISNPVTLTCDA 3175
Query: 271 SPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQGNASLRLQRV 330
+ P ++A L H E D + G + L++ R
Sbjct: 3176 TGIPPPTIAWLK-----------NHKRIENSDS----------LEVRILSGGSKLQIARS 3214
Query: 331 RVADEGSFTCFVS-IRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGY 389
+ +D G++TC S + L + P S + + + G+ V + C++ G
Sbjct: 3215 QHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNA-NGI 3273
Query: 390 PEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQD 448
P + W G P+ T + G ++ + G Y+C+ NP ++D
Sbjct: 3274 PTPLIQWLK-DGKPIASGETERIRVSANG--STLNIYGALTSDTGKYTCVATNPAGEED 3329
Score = 57.0 bits (136), Expect = 4e-08
Identities = 74/304 (24%), Positives = 125/304 (41%), Gaps = 60/304 (19%)
Query: 107 LRLQRVRVADEGSFTCFVSIRDFGSAA--VSLQVAAPYSKPSMTLEP-NKDLRPGDTVTI 163
L++Q + D G +TC V+I + G A ++L V +P P EP + + G VT+
Sbjct: 757 LKIQETQDLDAGDYTC-VAINEAGRATGKITLDVGSP---PVFIQEPADVSMEIGSNVTL 812
Query: 164 TCSSYQGYPEAEVFWQDGQGVPLTG---NVTTSQMANEQGLFDVHSILRVVLGANGTYSC 220
C QGYPE + W+ +P+ +V++ LF IL + GTY C
Sbjct: 813 PCY-VQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF----ILNLWASDKGTYIC 867
Query: 221 LVRNPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPVVALV--GTDATLRCSF---SPEPG 275
N + + ++VT+ TG V + P VA V G TL C+ +P P
Sbjct: 868 EAENQFGKIQSETTVTV------TGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIP- 920
Query: 276 FSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQGNASLRLQRVRVADE 335
W + ++ L+ + P + + + SL ++RV++ D
Sbjct: 921 ------ERRW-IKNSAMLLQN------------------PYITVRSDGSLHIERVQLQDG 955
Query: 336 GSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLR---PGDTVTITCSSYRGYPEA 392
G +TC S A + + + T++ + + G VT+ C + G P+
Sbjct: 956 GEYTCVAS----NVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKA-SGNPKP 1010
Query: 393 EVFW 396
V W
Sbjct: 1011 SVIW 1014
Score = 54.3 bits (129), Expect = 3e-07
Identities = 97/442 (21%), Positives = 168/442 (38%), Gaps = 62/442 (14%)
Query: 99 LLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPG 158
L+ G L++ R +V D G +TC V++ + G SLQ P + N DL
Sbjct: 2825 LILPGGRVLQIPRAKVEDAGRYTC-VAVNEAGED--SLQYDVRVLVPPIIKGANSDLPEE 2881
Query: 159 DTVTITCSSY-----QGYPEAEVFWQ-DGQGVPLTGNVTTSQMANEQGLFDVHSILRVVL 212
TV + S+ G P WQ DGQ PL + ++N + + IL +
Sbjct: 2882 VTVLVNKSALIECLSSGSPAPRNSWQKDGQ--PLLEDDHHKFLSNGR----ILQILNTQI 2935
Query: 213 GANGTYSCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSFSP 272
G Y C+ N + ++ + S G + + +V +L C S
Sbjct: 2936 TDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGP-----KSENLTVVVNNFISLTCEVSG 2990
Query: 273 EPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQGNASLRLQRVRV 332
P L+ L +Q T + P G +L++ R +V
Sbjct: 2991 FPPPDLSWLK------------------NEQPIKLNTNTLIVP-----GGRTLQIIRAKV 3027
Query: 333 ADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDL-----RPGDTVTITCSSYR 387
+D G +TC ++I G + + Y PS+ ++ L R G +V++ C S
Sbjct: 3028 SDGGEYTC-IAINQAGESKKKFSLTV-YVPPSIKDHDSESLSVVNVREGTSVSLECESNA 3085
Query: 388 GYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQ 447
P ++++G+ +T + +A+ Q L + + + G Y C N +
Sbjct: 3086 VPPPVITWYKNGR--MITESTHVEILADGQML----HIKKAEVSDTGQYVCRAINVAGRD 3139
Query: 448 DAHGSVTITGQPMTFPP--EALWVTVGLSVCLI--ALLVALAFVCWRKIKQSCEEENAGA 503
D + + + P P E + T+ V L A + + W +K EN+ +
Sbjct: 3140 DKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAW--LKNHKRIENSDS 3197
Query: 504 EDQDGEGEGSKTALQPLKHSDS 525
+ GSK + +HSDS
Sbjct: 3198 LEVRILSGGSKLQIARSQHSDS 3219
Score = 51.2 bits (121), Expect = 2e-06
Identities = 85/377 (22%), Positives = 146/377 (38%), Gaps = 62/377 (16%)
Query: 100 LAQGNASLRLQRVRVADEGSFTCFV------SIRDFGSAAVSLQVAAPYSKPSMTLEPNK 153
+ G LRL + + D G +TC V + FG + + P+ TLE K
Sbjct: 2435 ILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSV----LVPPHIVGENTLEDVK 2490
Query: 154 DLRPGDTVTITCSSYQGYPEAEVFW-QDGQGVPLTGNVTTSQMANEQGLFDVHSILRVVL 212
++ +VT+TC G P E+ W +DGQ PL + ++ + L I V +
Sbjct: 2491 -VKEKQSVTLTC-EVTGNPVPEITWHKDGQ--PLQEDEAHHIISGGRFL----QITNVQV 2542
Query: 213 GANGTYSCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSFSP 272
G Y+CL +P + S+ + + G PED V ++ + +L C
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPED-VTVILNSPTSLVCE--- 2598
Query: 273 EPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQGNASLRLQRVRV 332
+S + W F +G S NR + G +L++ +
Sbjct: 2599 --AYSYPPATITW-----------FKDGTPLES---NRNI----RILPGGRTLQILNAQE 2638
Query: 333 ADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMT--------LEPNK-DLRPGDTVTITC 383
+ G ++C V+ + G +V Y P + L P + ++ +T+T+ C
Sbjct: 2639 DNAGRYSC-VATNEAGEMIKHYEVKV-YIPPIINKGDLWGPGLSPKEVKIKVNNTLTLEC 2696
Query: 384 SSYRGYPEAEVFW-QDGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRN 442
+Y P A + W +DGQ PL + + AN L + + G Y+C+ N
Sbjct: 2697 EAY-AIPSASLSWYKDGQ--PLKSDDHVNIAANGHTL----QIKEAQISDTGRYTCVASN 2749
Query: 443 PVLQQDAHGSVTITGQP 459
+ + V I P
Sbjct: 2750 IAGEDELDFDVNIQVPP 2766
Score = 48.9 bits (115), Expect = 1e-05
Identities = 56/192 (29%), Positives = 77/192 (40%), Gaps = 34/192 (17%)
Query: 207 ILRVVLGANGTYSCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPVVALVGTDATL 266
I +V L G Y C+ + A + ++ + P +QVP + V G A L
Sbjct: 486 IAKVTLSDEGFYECIAVSSAGTGRAQTFFDVS-EPPPV----IQVPNN-VTVTPGERAVL 539
Query: 267 RCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQGNASLR 326
C S NL WQ D RD A R + N SL
Sbjct: 540 TCLI-----ISAVDYNLTWQRND-----------RDVRLAEPAR------IRTLANLSLE 577
Query: 327 LQRVRVADEGSFTCFVSIRDFGSAA-VSLQVAAPYSKPSMTLEP-NKDLRPGDTVTITCS 384
L+ V+ D G + C VS SAA V L V P P +T+ P N+ G V+I CS
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEP---PKVTVMPKNQSFTGGSEVSIMCS 634
Query: 385 SYRGYPEAEVFW 396
+ GYP+ ++ W
Sbjct: 635 A-TGYPKPKIAW 645
Score = 44.7 bits (104), Expect = 2e-04
Identities = 87/405 (21%), Positives = 150/405 (37%), Gaps = 59/405 (14%)
Query: 99 LLAQGNASLRLQRVRVADEGSFTCFVSIR-DFGSAAVSLQVAAPYSKPSMTLEPNKDLRP 157
LLA G +R+ R +V+D +TC S R + +LQV AP + + +
Sbjct: 3391 LLAAGQV-IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLK 3449
Query: 158 GDTVTITCSSYQGYPEAEVFW-QDGQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANG 216
G + ++ C + G P + W +DGQ + L ++T S G+ V +L+ +G
Sbjct: 3450 GSSTSMACIT-DGTPAPSMAWLRDGQPLGLDAHLTVS----THGM--VLQLLKAETEDSG 3502
Query: 217 TYSCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGF 276
Y+C+ N + H + + G+ E + + +V L C S P
Sbjct: 3503 KYTCIASNEAGEVSKHFILKVLEPPHINGSEE----HEEISVIVNNPLELTCIASGIPAP 3558
Query: 277 SLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEG 336
+ + L T Q+ T G G LR+ +V D G
Sbjct: 3559 KMTWMKDGRPLPQTDQVQ---TLG--------------------GGEVLRISTAQVEDTG 3595
Query: 337 SFTCFVSI-------RDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGY 389
+TC S V +A +T+ N+ VT+ C S
Sbjct: 3596 RYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQ------VTLECKSDAVP 3649
Query: 390 PEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDA 449
P + ++G+ + T V ++ + L + LG Y+C+ N +
Sbjct: 3650 PPVITWLRNGERLQATPRVRI--LSGGRYL----QINNADLGDTANYTCVASNIAGKTTR 3703
Query: 450 HGSVTITGQP-MTFPPEALWVTVGLSVCL--IALLVALAFVCWRK 491
+T+ P + P++L + + S L IA V + WRK
Sbjct: 3704 EFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRK 3748
Score = 41.6 bits (96), Expect = 0.002
Identities = 76/355 (21%), Positives = 130/355 (36%), Gaps = 53/355 (14%)
Query: 97 PDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLR 156
P + + + SL ++RV++ D G +TC S A + + + T++ + +
Sbjct: 935 PYITVRSDGSLHIERVQLQDGGEYTCVAS----NVAGTNNKTTSVVVHVLPTIQHGQQIL 990
Query: 157 ---PGDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSILRVVLG 213
G VT+ C + G P+ V W + T + S A+ S+ V G
Sbjct: 991 STIEGIPVTLPCKA-SGNPKPSVIWSKKGELISTSSAKFSAGAD-------GSLYVVSPG 1042
Query: 214 A--NGTYSCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPV--VALVGTDATLRCS 269
+G Y C N +T+ + G + PV L G + TL C
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCE 1102
Query: 270 FSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQGNASLRLQR 329
SL + W QL+ S ++ R P + S+++
Sbjct: 1103 VK-----SLPPPIITW--AKETQLI----------SPFSPRHTFLP------SGSMKITE 1139
Query: 330 VRVADEGSFTCF-VSIRDFGSAAVSLQVAAPYSKPSMTLEP-NKDLRPGDTVTITCSSYR 387
R +D G + C +I + AV L V P P + P + ++ G V I C++ +
Sbjct: 1140 TRTSDSGMYLCVATNIAGNVTQAVKLNVHVP---PKIQRGPKHLKVQVGQRVDIPCNA-Q 1195
Query: 388 GYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRN 442
G P + W G L ++N G S+ + G Y+C+ N
Sbjct: 1196 GTPLPVITWSKGGSTMLVDG--EHHVSNPDGTL---SIDQATPSDAGIYTCVATN 1245
Score = 34.3 bits (77), Expect = 0.29
Identities = 71/361 (19%), Positives = 140/361 (38%), Gaps = 62/361 (17%)
Query: 104 NASLRLQRVRVADEGSFTCFVSIRDFGSAA--VSLQVAAPYSKPSMTLEPNK-DLRPGDT 160
+ ++ + ++ G +TC V+ GSA V+L V P P + +P++ + +
Sbjct: 3949 SGAIEILATQLNHAGRYTC-VARNAAGSAHRHVTLHVHEP---PVIQPQPSELHVILNNP 4004
Query: 161 VTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANGTYSC 220
+ + C + G P + WQ +G+ + + + GL I R V GTY C
Sbjct: 4005 ILLPCEA-TGTPSPFITWQK-EGINVNTSGRNHAVLPSGGL----QISRAVREDAGTYMC 4058
Query: 221 LVRNPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPVVA------LVGTDATLRCSFSPEP 274
+ +NP + G +++ V PV++ ++ D + S +
Sbjct: 4059 VAQNPA--------------GTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEAD- 4103
Query: 275 GFSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQGNASLRLQRVRVAD 334
L ++ W D + +V S + +L+ G SL++ V+ D
Sbjct: 4104 --GLPPPDITWH-KDGRAIVESIRQ----------------RVLSSG--SLQIAFVQPGD 4142
Query: 335 EGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEV 394
G +TC ++ GS++ S ++ + E + + + C + G P +
Sbjct: 4143 AGHYTC-MAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVA-DGIPTPAI 4200
Query: 395 FWQDGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVT 454
W+ L N+ A G + + VVL +G Y+C+ N + S+T
Sbjct: 4201 NWKKDN--VLLANLLGKYTAEPYGELILEN---VVLEDSGFYTCVANNAAGEDTHTVSLT 4255
Query: 455 I 455
+
Sbjct: 4256 V 4256
Score = 33.5 bits (75), Expect = 0.50
Identities = 40/180 (22%), Positives = 72/180 (40%), Gaps = 42/180 (23%)
Query: 325 LRLQRVRVADEGSFTCFVSIRDFGSAAVSLQV---AAPYSKPSMTLEPNKDLRPGDTVTI 381
L + R +V+D ++TC V+ G+A S V P + ++ NK + ++T+
Sbjct: 1603 LHIPRAQVSDSATYTCHVA-NVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTL 1661
Query: 382 TCSSYRGYPEAEVFWQDGQGVPLTGN---------------------------VTTSQMA 414
C + G P + W GVP+ N V TS
Sbjct: 1662 ECKA-AGNPSPILTWLK-DGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAG 1719
Query: 415 NEQGLFDVHSVLRVVL--GANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVG 472
++ ++V ++ + G +Y ++ N +L+ D H +TG P PP +W+ G
Sbjct: 1720 EKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCH----VTGSP---PPTIMWLKDG 1772
Score = 30.8 bits (68), Expect = 3.2
Identities = 83/405 (20%), Positives = 137/405 (33%), Gaps = 64/405 (15%)
Query: 100 LAQGNASLRLQRVRVADEGSFTCFVS-IRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPG 158
+ G L++ + D ++TC S I + L V P P++ P +
Sbjct: 3670 ILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVP---PNIKGGPQSLVILL 3726
Query: 159 DTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANGTY 218
+ T+ +G P + W+ G L GN + E G + S + G Y
Sbjct: 3727 NKSTVLECIAEGVPTPRITWRK-DGAVLAGNHARYSIL-ENGFLHIQS---AHVTDTGRY 3781
Query: 219 SCLVRNPV------LQQDAHSSVTITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSFS- 271
C+ N + H +I P PT + +V TL C +
Sbjct: 3782 LCMATNAAGTDRRRIDLQVHVPPSIAP--GPTN----------MTVIVNVQTTLACEATG 3829
Query: 272 -PEPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQGNASLRLQRV 330
P+P + W+ H ++Q S LL+ G SL +
Sbjct: 3830 IPKPSIN-------WRKNG-----HLLNVDQNQNSYR---------LLSSG--SLVIISP 3866
Query: 331 RVADEGSFTCFVSI-RDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGY 389
V D ++ C V+ V L V P PS+ EP L + + G
Sbjct: 3867 SVDDTATYECTVTNGAGDDKRTVDLTVQVP---PSIADEPTDFLVTKHAPAVITCTASGV 3923
Query: 390 PEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDA 449
P + W G+ L ++ + + +L L G Y+C+ RN
Sbjct: 3924 PFPSIHWTKN-GIRLLPRGDGYRILSSGAI----EILATQLNHAGRYTCVARNAAGSAHR 3978
Query: 450 HGSVTITGQPMTFP-PEALWVTVGLSVCL--IALLVALAFVCWRK 491
H ++ + P+ P P L V + + L A F+ W+K
Sbjct: 3979 HVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQK 4023
Score = 29.6 bits (65), Expect = 7.2
Identities = 29/135 (21%), Positives = 55/135 (40%), Gaps = 12/135 (8%)
Query: 107 LRLQRVRVADEGSFTCFVSIRDFGSAAVSLQV---AAPYSKPSMTLEPNKDLRPGDTVTI 163
L + R +V+D ++TC V+ G+A S V P + ++ NK + ++T+
Sbjct: 1603 LHIPRAQVSDSATYTCHVA-NVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTL 1661
Query: 164 TCSSYQGYPEAEVFW-QDGQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANGTYSCLV 222
C + G P + W +DG V N+ + + I R G Y C+
Sbjct: 1662 ECKA-AGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDR------GQYICVA 1714
Query: 223 RNPVLQQDAHSSVTI 237
+ +++ V +
Sbjct: 1715 TSVAGEKEIKYEVDV 1729
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 69.7 bits (169), Expect = 6e-12
Identities = 85/348 (24%), Positives = 139/348 (39%), Gaps = 54/348 (15%)
Query: 105 ASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLR--PGDTVT 162
A+L+ RV A+ G +TC + D G ++ +P+ +E + ++ GDT T
Sbjct: 7548 ATLQFSRVEPANAGKYTCQIK-NDAGMQECFATLSV--LEPATIVEKPESIKVTTGDTCT 7604
Query: 163 ITCSSYQGYPEAEVFW-QDGQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANGTYSCL 221
+ C+ G PE W +DG+ + S GL I+ V +G YS
Sbjct: 7605 LECT-VAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGL----KIINVAPSDSGVYSFE 7659
Query: 222 VRNPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQL 281
V+NPV + +S+ ++ + P + L G+ + C P S++
Sbjct: 7660 VQNPVGKDSCTASLQVSDRTVPPSFTRKLKETN---GLSGSSVVMECKVYGSPPISVS-- 7714
Query: 282 NLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCF 341
W F EG + S +T L +L + + +D G +TC
Sbjct: 7715 ---W-----------FHEGNEISSGRKYQTT-----LTDNTCALTVNMLEESDSGDYTCI 7755
Query: 342 VSIRDFGSAAVSLQVAAPYS---KPSMTLEPN-KDLRPGDTVTITCSSYRGYPEAEVFWQ 397
+ + A S + +AP + PS +P+ D+ G VT T S +G P V W
Sbjct: 7756 AT-----NMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFT-SIVKGTPPFSVSWF 7809
Query: 398 DGQGVPLTG---NVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRN 442
G + G NV+ E LFDV + +G Y+C+V N
Sbjct: 7810 KGSSELVPGDRCNVSLEDSVAELELFDVDT------SQSGEYTCIVSN 7851
Score = 57.4 bits (137), Expect = 3e-08
Identities = 99/451 (21%), Positives = 162/451 (35%), Gaps = 68/451 (15%)
Query: 36 DPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTAL 95
+P+ A VG +L C + P ++ + W DTK T
Sbjct: 6086 EPLEAAVGDSVSLQCQVAGTP-----EITVSWYKGDTK----------------LRPTPE 6124
Query: 96 FPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVS--LQVAAPYSKPSMTLEPNK 153
+ A+L +V + D G +TC G+A+ ++ PS + K
Sbjct: 6125 YRTYFTNNVATLVFNKVNINDSGEYTCKAE-NSIGTASSKTVFRIQERQLPPSFARQL-K 6182
Query: 154 DLRP--GDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSILRVV 211
D+ G VT+TC P +++DG + N+ TS + N L IL+
Sbjct: 6183 DIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATL----KILQTD 6238
Query: 212 LGANGTYSCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSFS 271
L +G YSC NP+ A SS +T R P + + + + G A C +
Sbjct: 6239 LSHSGQYSCSASNPL--GTASSSARLT-AREPKKSPFFDIKPVSIDVIAGESADFECHVT 6295
Query: 272 PEPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQGNA-SLRLQRV 330
+ + W D K++ G Y + GN LR+ +V
Sbjct: 6296 -----GAQPMRITWS-KDNKEI--------RPGGNYT--------ITCVGNTPHLRILKV 6333
Query: 331 RVADEGSFTCFVSI---RDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYR 387
D G +TC + +D SA +S++ + K LE +K + G+++ + C
Sbjct: 6334 GKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVK---KLEASKVAKQGESIQLEC-KIS 6389
Query: 388 GYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQ 447
G PE +V W N L ++ +G Y C N V
Sbjct: 6390 GSPEIKVSWFRNDSELHESWKYNMSFINSVALLTIN---EASAEDSGDYICEAHNGVGDA 6446
Query: 448 DAHGSVTITGQPM-TFPPEALWVTVGLSVCL 477
++T+ P+ T P + G V L
Sbjct: 6447 SCSTALTVKAPPVFTQKPSPVGALKGSDVIL 6477
Score = 55.8 bits (133), Expect = 9e-08
Identities = 86/383 (22%), Positives = 143/383 (37%), Gaps = 68/383 (17%)
Query: 107 LRLQRVRVADEGSFTCFVSI---RDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTI 163
LR+ +V D G +TC + +D SA +S++ + K LE +K + G+++ +
Sbjct: 6328 LRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKK---LEASKVAKQGESIQL 6384
Query: 164 TCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANGTYSCLVR 223
C G PE +V W N L ++ +G Y C
Sbjct: 6385 ECK-ISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINE---ASAEDSGDYICEAH 6440
Query: 224 NPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNL 283
N V DA S +T + P V Q P PV AL G+D L+C S P F +
Sbjct: 6441 NGV--GDASCSTALTVKAPP---VFTQKPS-PVGALKGSDVILQCEISGTPPF-----EV 6489
Query: 284 IWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVS 343
+W + D KQ+ +S F + SL + + +D G + C +
Sbjct: 6490 VW-VKDRKQVRNS---------------KKFKITSKHFDTSLHILNLEASDVGEYHC-KA 6532
Query: 344 IRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRP--GDTVTITCSSYRGYPEAEVFWQDGQG 401
+ GS S V + +P ++ D GD V + + G+ V W +G
Sbjct: 6533 TNEVGSDTCSCSV--KFKEPPRFVKKLSDTSTLIGDAVELR-AIVEGFQPISVVWLKDRG 6589
Query: 402 ----------VPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHG 451
+ N+ T Q+ + + +G Y C ++N ++
Sbjct: 6590 EVIRESENTRISFIDNIATLQLGSPEA------------SNSGKYICQIKNDAGMRECSA 6637
Query: 452 SVTITGQPMTF--PPEALWVTVG 472
+T+ +P PE + VT G
Sbjct: 6638 VLTVL-EPARIIEKPEPMTVTTG 6659
Score = 55.1 bits (131), Expect = 2e-07
Identities = 84/386 (21%), Positives = 145/386 (37%), Gaps = 51/386 (13%)
Query: 79 FAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTC----FVSIRDFGSAAV 134
F +G++ ++ R A +G ASL + RV + D G+FTC V +D A +
Sbjct: 4147 FKDGKEIAASDRYRIAF-----VEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALI 4201
Query: 135 SLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQ 194
+ + +KP +KD+ PG V + S++QG + W G ++G S
Sbjct: 4202 VQEPPSFVTKPG-----SKDVLPGSAVCLK-STFQGSTPLTIRWFKGNKELVSGG---SC 4252
Query: 195 MANEQGLFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQVPED 254
++ L + V +GTY+C V N + +++ + + P VE +
Sbjct: 4253 YITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFV---KEPATFVE---KLE 4306
Query: 255 PVVALVGTDAT-LRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTAL 313
P L DAT L C + P + + W F R+ + +R +
Sbjct: 4307 PSQLLKKGDATQLACKVTGTP-----PIKITW-----------FANDREIKESSKHRMS- 4349
Query: 314 FPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDL 373
+ A LRL V + D G + C S+ + + +P + L
Sbjct: 4350 ----FVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVL 4405
Query: 374 RPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGAN 433
+ D + + + G P E+ W + +G + + Q +L+ V
Sbjct: 4406 KEYDVMLL--AEVAGTPPFEITWFKDNTILRSGRKYKTFI---QDHLVSLQILKFVAADA 4460
Query: 434 GTYSCLVRNPVLQQDAHGSVTITGQP 459
G Y C V N V VT+ P
Sbjct: 4461 GEYQCRVTNEVGSSICSARVTLREPP 4486
Score = 54.7 bits (130), Expect = 2e-07
Identities = 84/366 (22%), Positives = 150/366 (40%), Gaps = 50/366 (13%)
Query: 105 ASLRLQRVRVADEGSFTCFV-SIRDFGSAAVSLQVAAPYSKPSMTLEPNK-DLRPGDTVT 162
A L + + V D G +TC + S++ SL+V P P +P+ + G V
Sbjct: 7361 AVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEP---PIFRKKPHPIETLKGADVH 7417
Query: 163 ITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANGTYSCLV 222
+ C QG P V W + +G ++ +E L +H IL V G Y C
Sbjct: 7418 LECE-LQGTPPFHVSWYKDKRELRSGK--KYKIMSENFLTSIH-ILNVDAADIGEYQCKA 7473
Query: 223 RNPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSFS-PEPGFSLAQL 281
N V S+ + ++P V+ + +VG + L+ + EP +
Sbjct: 7474 TNDVGSDTCVGSIAL---KAPPRFVKKL---SDISTVVGKEVQLQTTIEGAEP------I 7521
Query: 282 NLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCF 341
+++W D ++V R+ + + + ++ A+L+ RV A+ G +TC
Sbjct: 7522 SVVW-FKDKGEIV------RESDNIWIS--------YSENIATLQFSRVEPANAGKYTCQ 7566
Query: 342 VSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLR--PGDTVTITCSSYRGYPEAEVFW-QD 398
+ D G ++ +P+ +E + ++ GDT T+ C+ G PE W +D
Sbjct: 7567 IK-NDAGMQECFATLSV--LEPATIVEKPESIKVTTGDTCTLECT-VAGTPELSTKWFKD 7622
Query: 399 GQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQ 458
G+ + S GL ++ V +G YS V+NPV + S+ ++ +
Sbjct: 7623 GKELTSDNKYKISFFNKVSGL----KIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDR 7678
Query: 459 PMTFPP 464
T PP
Sbjct: 7679 --TVPP 7682
Score = 53.9 bits (128), Expect = 4e-07
Identities = 86/392 (21%), Positives = 152/392 (38%), Gaps = 51/392 (13%)
Query: 100 LAQGNASLRLQRVRVADEGSFTCFVSI---RDFGSAAVSLQVAAPYSKPSMTLEPNKDLR 156
L + A+L + +V D G +TC+ S +D SA + +Q + K LEP++ ++
Sbjct: 7262 LVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFIK---KLEPSRIVK 7318
Query: 157 PGDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANG 216
+ C G PE +V W + + + + ++H++ + +G
Sbjct: 7319 QDEFTRYEC-KIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNL---SVEDSG 7374
Query: 217 TYSCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGF 276
Y+C N A SS ++ + P + P+ L G D L C P F
Sbjct: 7375 DYTCEAHNAA--GSASSSTSLKVKEPPI----FRKKPHPIETLKGADVHLECELQGTPPF 7428
Query: 277 SLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEG 336
++ W D ++L G Y + F S+ + V AD G
Sbjct: 7429 HVS-----W-YKDKREL--------RSGKKYKIMSENF-------LTSIHILNVDAADIG 7467
Query: 337 SFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRP--GDTVTITCSSYRGYPEAEV 394
+ C + D GS +A P ++ D+ G V + + P + V
Sbjct: 7468 EYQC-KATNDVGSDTCVGSIA--LKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVV 7524
Query: 395 FWQD-GQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSV 453
+++D G+ V + N+ S N L RV G Y+C ++N Q+ ++
Sbjct: 7525 WFKDKGEIVRESDNIWISYSENIATL----QFSRVEPANAGKYTCQIKNDAGMQECFATL 7580
Query: 454 TITGQPMTF--PPEALWVTVGLSVCLIALLVA 483
++ +P T PE++ VT G C + VA
Sbjct: 7581 SVL-EPATIVEKPESIKVTTG-DTCTLECTVA 7610
Score = 48.1 bits (113), Expect = 2e-05
Identities = 87/415 (20%), Positives = 157/415 (37%), Gaps = 64/415 (15%)
Query: 36 DPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTAL 95
+PV VG A+L C + P ++ + W DTK T
Sbjct: 7968 EPVKVSVGDSASLQCQLAGTP-----EIGVSWYKGDTK----------------LRPTTT 8006
Query: 96 FPDLLAQGNASLRLQRVRVADEGSFTCFV--SIRDFGSAAVSLQVAAPYSKPSMTLEPNK 153
+ A+L +V + D G + C S+ + SA+ L V PS + + +
Sbjct: 8007 YKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEV-SASTFLTVQEQKLPPSFSRQL-R 8064
Query: 154 DLRP--GDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSILRVV 211
D++ G V C+ P + +++DG+ + + NV TS + N L +I +
Sbjct: 8065 DVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATL----NIFKTD 8120
Query: 212 LGANGTYSCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSFS 271
G YSC NP+ + + + +T ++P + PV A+VG A C +
Sbjct: 8121 RSLAGQYSCTATNPIGSASSSARLILTEGKNPP---FFDIRLAPVDAVVGESADFECHVT 8177
Query: 272 PEPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQGNASLRLQRVR 331
+ + W D++++ + G+ Q S N +A L + +V
Sbjct: 8178 -----GTQPIKVSW-AKDSREI---RSGGKYQISYLEN------------SAHLTVLKVD 8216
Query: 332 VADEGSFTCFVSIRDFG--SAAVSLQVAAPYSKPSMT--LEPNKDLRPGDTVTITCSSYR 387
D G +TC+ ++ + G S L + PS T L + G++ +
Sbjct: 8217 KGDSGQYTCY-AVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAG 8275
Query: 388 GYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRN 442
P ++++ + T N + N V V + + G Y+C V N
Sbjct: 8276 SQPITVAWYKNNIEIQPTSNCEITFKNNTL----VLQVRKAGMNDAGLYTCKVSN 8326
Score = 45.1 bits (105), Expect = 2e-04
Identities = 97/472 (20%), Positives = 184/472 (38%), Gaps = 83/472 (17%)
Query: 28 ALEVQVPE------DPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAE 81
AL V+ P PV AL G+D L C S P F ++W + D KQ+ +S
Sbjct: 6451 ALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPF-----EVVW-VKDRKQVRNS--- 6501
Query: 82 GQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAP 141
F + SL + + +D G + C + + GS S V
Sbjct: 6502 ------------KKFKITSKHFDTSLHILNLEASDVGEYHC-KATNEVGSDTCSCSV--K 6546
Query: 142 YSKPSMTLEPNKDLRP--GDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQ 199
+ +P ++ D GD V + + +G+ V W +G + + T
Sbjct: 6547 FKEPPRFVKKLSDTSTLIGDAVELR-AIVEGFQPISVVWLKDRGEVIRESENTR------ 6599
Query: 200 GLFDVHSILRVVLGA-----NGTYSCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQVPED 254
+ + +I + LG+ +G Y C ++N ++ + +T+ P +E +
Sbjct: 6600 -ISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVL---EPARIIE---KPE 6652
Query: 255 PVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALF 314
P+ G L C + P +L+ W F +GR+ + +
Sbjct: 6653 PMTVTTGNPFALECVVTGTP-----ELSAKW-----------FKDGRELSADSKHHITFI 6696
Query: 315 PDLLAQGNASLRLQRVRVADEGSFTCFV-SIRDFGSAAVSLQVAAPYSKPSMTLEPNKDL 373
+ ASL++ ++D+G ++ V + + VS+ V+ PS + KD+
Sbjct: 6697 NKV-----ASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSF-IRKLKDV 6750
Query: 374 RP--GDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLG 431
G +V + C P + ++QDG + ++G S + ++ S+L
Sbjct: 6751 NAILGASVVLECRVSGSAPISVGWFQDGNEI-VSGPKCQSSFSENVCTLNL-SLLEP--S 6806
Query: 432 ANGTYSCLVRNPVLQQDAHGSVTITGQPMTF--PPEALWVTVGLSVCLIALL 481
G Y+C+ N V D +V +P +F P+++ V G+S+ +++
Sbjct: 6807 DTGIYTCVAAN-VAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVI 6857
Score = 37.4 bits (85), Expect = 0.035
Identities = 69/303 (22%), Positives = 114/303 (37%), Gaps = 47/303 (15%)
Query: 101 AQGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDT 160
A+ L L + + D G ++C S + FG+ ++ KP K+L P +
Sbjct: 3602 AENKHILELSNLTIQDRGVYSCKASNK-FGADICQAELII-IDKPHFI----KELEPVQS 3655
Query: 161 -----VTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGAN 215
V + C + + +DGQ +P + ++ E + + L L +
Sbjct: 3656 AINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDY---KICFEDKIATLEIPL-AKLKDS 3711
Query: 216 GTYSCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPG 275
GTY C N ++VT+ R P V+ P + L G A L C P
Sbjct: 3712 GTYVCTASNEAGSSSCSATVTV---REPPSFVKKVDPS--YLMLPGESARLHCKLKGSP- 3765
Query: 276 FSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQGNASLRLQRVRVADE 335
+ + W + K+L S N ++ A L + V+V D
Sbjct: 3766 ----VIQVTW-FKNNKELSES------------NTVRMY---FVNSEAILDITDVKVEDS 3805
Query: 336 GSFTCFVSIRDFGSAAVSLQVAAPYSKPSM--TLEPNKDLRPGDTVTITCSSYRGYPEAE 393
GS++C ++ D GS + S ++ PS TLEP D+ G + C G E
Sbjct: 3806 GSYSC-EAVNDVGSDSCSTEIVIK-EPPSFIKTLEP-ADIVRGTNALLQC-EVSGTGPFE 3861
Query: 394 VFW 396
+ W
Sbjct: 3862 ISW 3864
Score = 33.5 bits (75), Expect = 0.50
Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 5/80 (6%)
Query: 316 DLLAQGNASLRLQRVRVADEGSFTCFVSI---RDFGSAAVSLQVAAPYSKPSM--TLEPN 370
D L G ASLR+ V DEG +T F S S + ++ AAP P+ TLEP
Sbjct: 1340 DFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPV 1399
Query: 371 KDLRPGDTVTITCSSYRGYP 390
+R +++ S R P
Sbjct: 1400 SRIRSLSPRSVSRSPIRMSP 1419
Score = 33.5 bits (75), Expect = 0.50
Identities = 72/361 (19%), Positives = 119/361 (32%), Gaps = 54/361 (14%)
Query: 102 QGNASLRLQRVRVADEGSFTCFVSIRDFG--SAAVSLQVAAPYSKPSMT--LEPNKDLRP 157
+ +A L + +V D G +TC+ ++ + G S L + PS T L +
Sbjct: 8205 ENSAHLTVLKVDKGDSGQYTCY-AVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETE 8263
Query: 158 GDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANGT 217
G++ + P ++++ + T N + N L + + + G
Sbjct: 8264 GNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVL----QVRKAGMNDAGL 8319
Query: 218 YSCLVRNPVLQQDAHSSVTIT-PQRSPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGF 276
Y+C V N SS+ I P++ P + PV G L C
Sbjct: 8320 YTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLT----PVTVSEGEYVQLSCHVQGSEPI 8375
Query: 277 SLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEG 336
+ L ++ + + SF A G A L L+ V AD G
Sbjct: 8376 RIQWLKAGREIKPSDRCSFSF---------------------ASGTAVLELRDVAKADSG 8414
Query: 337 SFTC-------------FVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITC 383
+ C V+I+D + A + + AA + EP T
Sbjct: 8415 DYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFI 8474
Query: 384 SSYRGYPEAEVFWQDGQGVPLT--GNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVR 441
+ G P V W G+ L G V Q +E L + +G Y C+
Sbjct: 8475 AKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKL----EIRDTTKTDSGLYRCVAF 8530
Query: 442 N 442
N
Sbjct: 8531 N 8531
Score = 32.7 bits (73), Expect = 0.85
Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 98 DLLAQGNASLRLQRVRVADEGSFTCFVSI---RDFGSAAVSLQVAAPYSKPSM--TLEPN 152
D L G ASLR+ V DEG +T F S S + ++ AAP P+ TLEP
Sbjct: 1340 DFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPV 1399
Query: 153 KDLR 156
+R
Sbjct: 1400 SRIR 1403
Score = 32.3 bits (72), Expect = 1.1
Identities = 26/112 (23%), Positives = 42/112 (37%), Gaps = 7/112 (6%)
Query: 142 YSKPSMTLEPN-KD---LRPGDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMAN 197
Y P++ L+P KD ++ GDT+ + S G P + W ++T
Sbjct: 20373 YEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTP 20432
Query: 198 EQGLFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTITPQRSPTGAVEV 249
+ + R G Y+ NP + H VT+ P G VE+
Sbjct: 20433 TSSMLTIKYATRKDAGE---YTITATNPFGTKVEHVKVTVLDVPGPPGPVEI 20481
Score = 31.2 bits (69), Expect = 2.5
Identities = 49/204 (24%), Positives = 85/204 (41%), Gaps = 27/204 (13%)
Query: 105 ASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSM--TLEPNKDLRPGDTVT 162
A L + V+V D GS++C ++ D GS + S ++ PS TLEP D+ G
Sbjct: 3793 AILDITDVKVEDSGSYSC-EAVNDVGSDSCSTEIVIK-EPPSFIKTLEP-ADIVRGTNAL 3849
Query: 163 ITCSSYQGYPEAEVFW-QDGQGVPLTGNVTTSQMANEQGLFDVHSILRV-VLGAN----G 216
+ C G E+ W +D + + + + + LF S++ + + N G
Sbjct: 3850 LQC-EVSGTGPFEISWFKDKKQI---------RSSKKYRLFSQKSLVCLEIFSFNSADVG 3899
Query: 217 TYSCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGF 276
Y C+V N V T + PT +V D ++AL G TL+ +
Sbjct: 3900 EYECVVANEV--GKCGCMATHLLKEPPTFVKKV----DDLIALGGQTVTLQAAVRGSEPI 3953
Query: 277 SLAQLNLIWQLTDTKQLVHSFTEG 300
S+ + + + ++ SF+ G
Sbjct: 3954 SVTWMKGQEVIREDGKIKMSFSNG 3977
Score = 30.0 bits (66), Expect = 5.5
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 15/145 (10%)
Query: 158 GDTVTITCSSYQGYPEAEVFW-QDGQGVPLTGN--VTTSQMANEQGLFDVHSILRVVLGA 214
G++ +C + G P V W + GQ + + VTT++ + F++ S V
Sbjct: 32575 GESARFSCDT-DGEPVPTVTWLRKGQVLSTSARHQVTTTKY---KSTFEISS---VQASD 32627
Query: 215 NGTYSCLVRNPVLQQDAHSSVTI----TPQRSPTGAVEVQVPEDPVVALVGTDATLRCSF 270
G YS +V N +Q+A ++TI +++ T V+ PE V + + R
Sbjct: 32628 EGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVK- 32686
Query: 271 SPEPGFSLAQLNLIWQLTDTKQLVH 295
SPEP A + T T+++ H
Sbjct: 32687 SPEPSHPKAVSPTETKPTPTEKVQH 32711
>gi|56788393 myelin oligodendrocyte glycoprotein isoform beta5
precursor [Homo sapiens]
Length = 213
Score = 69.7 bits (169), Expect = 6e-12
Identities = 42/124 (33%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 242 SPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGR 301
S G V P P+ ALVG + L C SP G + + + W ++VH + G+
Sbjct: 27 SYAGQFRVIGPRHPIRALVGDEVELPCRISP--GKNATGMEVGWYRPPFSRVVHLYRNGK 84
Query: 302 DQGS----AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQV 356
DQ Y RT L D + +G +LR++ VR +DEG FTCF + AA+ L+V
Sbjct: 85 DQDGDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKV 144
Query: 357 AAPY 360
P+
Sbjct: 145 EDPF 148
Score = 68.9 bits (167), Expect = 1e-11
Identities = 41/121 (33%), Positives = 60/121 (49%), Gaps = 7/121 (5%)
Query: 27 GALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQG 86
G V P P+ ALVG + L C SP G + + + W ++VH + G+DQ
Sbjct: 30 GQFRVIGPRHPIRALVGDEVELPCRISP--GKNATGMEVGWYRPPFSRVVHLYRNGKDQD 87
Query: 87 S----AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAP 141
Y RT L D + +G +LR++ VR +DEG FTCF + AA+ L+V P
Sbjct: 88 GDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEDP 147
Query: 142 Y 142
+
Sbjct: 148 F 148
>gi|56788391 myelin oligodendrocyte glycoprotein isoform beta2
precursor [Homo sapiens]
Length = 206
Score = 69.7 bits (169), Expect = 6e-12
Identities = 42/124 (33%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 242 SPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGR 301
S G V P P+ ALVG + L C SP G + + + W ++VH + G+
Sbjct: 27 SYAGQFRVIGPRHPIRALVGDEVELPCRISP--GKNATGMEVGWYRPPFSRVVHLYRNGK 84
Query: 302 DQGS----AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQV 356
DQ Y RT L D + +G +LR++ VR +DEG FTCF + AA+ L+V
Sbjct: 85 DQDGDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKV 144
Query: 357 AAPY 360
P+
Sbjct: 145 EDPF 148
Score = 68.9 bits (167), Expect = 1e-11
Identities = 41/121 (33%), Positives = 60/121 (49%), Gaps = 7/121 (5%)
Query: 27 GALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQG 86
G V P P+ ALVG + L C SP G + + + W ++VH + G+DQ
Sbjct: 30 GQFRVIGPRHPIRALVGDEVELPCRISP--GKNATGMEVGWYRPPFSRVVHLYRNGKDQD 87
Query: 87 S----AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAP 141
Y RT L D + +G +LR++ VR +DEG FTCF + AA+ L+V P
Sbjct: 88 GDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEDP 147
Query: 142 Y 142
+
Sbjct: 148 F 148
>gi|56788389 myelin oligodendrocyte glycoprotein isoform alpha3
precursor [Homo sapiens]
Length = 224
Score = 69.7 bits (169), Expect = 6e-12
Identities = 42/124 (33%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 242 SPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGR 301
S G V P P+ ALVG + L C SP G + + + W ++VH + G+
Sbjct: 27 SYAGQFRVIGPRHPIRALVGDEVELPCRISP--GKNATGMEVGWYRPPFSRVVHLYRNGK 84
Query: 302 DQGS----AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQV 356
DQ Y RT L D + +G +LR++ VR +DEG FTCF + AA+ L+V
Sbjct: 85 DQDGDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKV 144
Query: 357 AAPY 360
P+
Sbjct: 145 EDPF 148
Score = 68.9 bits (167), Expect = 1e-11
Identities = 41/121 (33%), Positives = 60/121 (49%), Gaps = 7/121 (5%)
Query: 27 GALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQG 86
G V P P+ ALVG + L C SP G + + + W ++VH + G+DQ
Sbjct: 30 GQFRVIGPRHPIRALVGDEVELPCRISP--GKNATGMEVGWYRPPFSRVVHLYRNGKDQD 87
Query: 87 S----AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAP 141
Y RT L D + +G +LR++ VR +DEG FTCF + AA+ L+V P
Sbjct: 88 GDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEDP 147
Query: 142 Y 142
+
Sbjct: 148 F 148
>gi|56788387 myelin oligodendrocyte glycoprotein isoform beta3
precursor [Homo sapiens]
Length = 229
Score = 69.7 bits (169), Expect = 6e-12
Identities = 42/124 (33%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 242 SPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGR 301
S G V P P+ ALVG + L C SP G + + + W ++VH + G+
Sbjct: 27 SYAGQFRVIGPRHPIRALVGDEVELPCRISP--GKNATGMEVGWYRPPFSRVVHLYRNGK 84
Query: 302 DQGS----AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQV 356
DQ Y RT L D + +G +LR++ VR +DEG FTCF + AA+ L+V
Sbjct: 85 DQDGDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKV 144
Query: 357 AAPY 360
P+
Sbjct: 145 EDPF 148
Score = 68.9 bits (167), Expect = 1e-11
Identities = 41/121 (33%), Positives = 60/121 (49%), Gaps = 7/121 (5%)
Query: 27 GALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQG 86
G V P P+ ALVG + L C SP G + + + W ++VH + G+DQ
Sbjct: 30 GQFRVIGPRHPIRALVGDEVELPCRISP--GKNATGMEVGWYRPPFSRVVHLYRNGKDQD 87
Query: 87 S----AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAP 141
Y RT L D + +G +LR++ VR +DEG FTCF + AA+ L+V P
Sbjct: 88 GDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEDP 147
Query: 142 Y 142
+
Sbjct: 148 F 148
>gi|56788385 myelin oligodendrocyte glycoprotein isoform beta1
precursor [Homo sapiens]
Length = 252
Score = 69.7 bits (169), Expect = 6e-12
Identities = 42/124 (33%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 242 SPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGR 301
S G V P P+ ALVG + L C SP G + + + W ++VH + G+
Sbjct: 27 SYAGQFRVIGPRHPIRALVGDEVELPCRISP--GKNATGMEVGWYRPPFSRVVHLYRNGK 84
Query: 302 DQGS----AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQV 356
DQ Y RT L D + +G +LR++ VR +DEG FTCF + AA+ L+V
Sbjct: 85 DQDGDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKV 144
Query: 357 AAPY 360
P+
Sbjct: 145 EDPF 148
Score = 68.9 bits (167), Expect = 1e-11
Identities = 41/121 (33%), Positives = 60/121 (49%), Gaps = 7/121 (5%)
Query: 27 GALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQG 86
G V P P+ ALVG + L C SP G + + + W ++VH + G+DQ
Sbjct: 30 GQFRVIGPRHPIRALVGDEVELPCRISP--GKNATGMEVGWYRPPFSRVVHLYRNGKDQD 87
Query: 87 S----AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAP 141
Y RT L D + +G +LR++ VR +DEG FTCF + AA+ L+V P
Sbjct: 88 GDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEDP 147
Query: 142 Y 142
+
Sbjct: 148 F 148
>gi|56788383 myelin oligodendrocyte glycoprotein isoform alpha2
precursor [Homo sapiens]
Length = 208
Score = 69.7 bits (169), Expect = 6e-12
Identities = 42/124 (33%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 242 SPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGR 301
S G V P P+ ALVG + L C SP G + + + W ++VH + G+
Sbjct: 27 SYAGQFRVIGPRHPIRALVGDEVELPCRISP--GKNATGMEVGWYRPPFSRVVHLYRNGK 84
Query: 302 DQGS----AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQV 356
DQ Y RT L D + +G +LR++ VR +DEG FTCF + AA+ L+V
Sbjct: 85 DQDGDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKV 144
Query: 357 AAPY 360
P+
Sbjct: 145 EDPF 148
Score = 68.9 bits (167), Expect = 1e-11
Identities = 41/121 (33%), Positives = 60/121 (49%), Gaps = 7/121 (5%)
Query: 27 GALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQG 86
G V P P+ ALVG + L C SP G + + + W ++VH + G+DQ
Sbjct: 30 GQFRVIGPRHPIRALVGDEVELPCRISP--GKNATGMEVGWYRPPFSRVVHLYRNGKDQD 87
Query: 87 S----AYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAP 141
Y RT L D + +G +LR++ VR +DEG FTCF + AA+ L+V P
Sbjct: 88 GDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEDP 147
Query: 142 Y 142
+
Sbjct: 148 F 148
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,786,967
Number of Sequences: 37866
Number of extensions: 1022620
Number of successful extensions: 5012
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 93
Number of HSP's successfully gapped in prelim test: 258
Number of HSP's that attempted gapping in prelim test: 3415
Number of HSP's gapped (non-prelim): 1347
length of query: 534
length of database: 18,247,518
effective HSP length: 107
effective length of query: 427
effective length of database: 14,195,856
effective search space: 6061630512
effective search space used: 6061630512
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.