BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|6679625 elastase 3B, pancreatic preproprotein [Homo sapiens] (270 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|6679625 elastase 3B, pancreatic preproprotein [Homo sapiens] 572 e-164 gi|236460050 elastase 3A, pancreatic preproprotein [Homo sapiens] 530 e-151 gi|15559207 elastase 2A preproprotein [Homo sapiens] 317 7e-87 gi|62526043 chymotrypsin C preproprotein [Homo sapiens] 302 2e-82 gi|58331211 elastase 2B preproprotein [Homo sapiens] 301 5e-82 gi|58331209 chymotrypsin-like elastase family, member 1 [Homo sa... 279 2e-75 gi|4503137 chymotrypsin-like [Homo sapiens] 197 8e-51 gi|118498341 chymotrypsin B1 [Homo sapiens] 193 2e-49 gi|118498350 chymotrypsin B2 [Homo sapiens] 191 8e-49 gi|4505881 plasminogen [Homo sapiens] 156 2e-38 gi|11545839 protease, serine, 22 [Homo sapiens] 155 3e-38 gi|110815798 ovochymase 1 [Homo sapiens] 151 5e-37 gi|33695155 hepsin [Homo sapiens] 148 4e-36 gi|4504481 hepsin [Homo sapiens] 148 4e-36 gi|68508970 tryptase beta 2 precursor [Homo sapiens] 146 2e-35 gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens] 146 2e-35 gi|58218970 protease, serine, 36 [Homo sapiens] 145 5e-35 gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens] 142 3e-34 gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 140 9e-34 gi|4506153 prostasin preproprotein [Homo sapiens] 139 2e-33 gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 137 8e-33 gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 136 2e-32 gi|148231605 ovochymase 2 [Homo sapiens] 136 2e-32 gi|117956391 protease, serine, 33 [Homo sapiens] 136 2e-32 gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 135 3e-32 gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] 135 5e-32 gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 134 6e-32 gi|4503627 coagulation factor XI precursor [Homo sapiens] 134 6e-32 gi|29244926 corin [Homo sapiens] 134 6e-32 gi|194018492 transmembrane protease, serine 11F [Homo sapiens] 133 2e-31 >gi|6679625 elastase 3B, pancreatic preproprotein [Homo sapiens] Length = 270 Score = 572 bits (1475), Expect = e-164 Identities = 270/270 (100%), Positives = 270/270 (100%) Query: 1 MMLRLLSSLLLVAVASGYGPPSSRPSSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGG 60 MMLRLLSSLLLVAVASGYGPPSSRPSSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGG Sbjct: 1 MMLRLLSSLLLVAVASGYGPPSSRPSSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGG 60 Query: 61 SLIAPDWVVTAGHCISSSRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVAC 120 SLIAPDWVVTAGHCISSSRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVAC Sbjct: 61 SLIAPDWVVTAGHCISSSRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVAC 120 Query: 121 GNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPDKLQEALL 180 GNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPDKLQEALL Sbjct: 121 GNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPDKLQEALL 180 Query: 181 PVVDYEHCSRWNWWGSSVKKTMVCAGGDIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVS 240 PVVDYEHCSRWNWWGSSVKKTMVCAGGDIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVS Sbjct: 181 PVVDYEHCSRWNWWGSSVKKTMVCAGGDIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVS 240 Query: 241 AFGCNTRRKPTVFTRVSAFIDWIEETIASH 270 AFGCNTRRKPTVFTRVSAFIDWIEETIASH Sbjct: 241 AFGCNTRRKPTVFTRVSAFIDWIEETIASH 270 >gi|236460050 elastase 3A, pancreatic preproprotein [Homo sapiens] Length = 270 Score = 530 bits (1365), Expect = e-151 Identities = 251/270 (92%), Positives = 258/270 (95%) Query: 1 MMLRLLSSLLLVAVASGYGPPSSRPSSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGG 60 MMLRLLSSLLLVAVASGYGPPSS SSRVV+GEDAVPYSWPWQVSLQYEKSGSFYHTCGG Sbjct: 1 MMLRLLSSLLLVAVASGYGPPSSHSSSRVVHGEDAVPYSWPWQVSLQYEKSGSFYHTCGG 60 Query: 61 SLIAPDWVVTAGHCISSSRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVAC 120 SLIAPDWVVTAGHCIS TYQVVLGEY+ AVKEGPEQVIPINS +LFVHPLWNRSCVAC Sbjct: 61 SLIAPDWVVTAGHCISRDLTYQVVLGEYNLAVKEGPEQVIPINSEELFVHPLWNRSCVAC 120 Query: 121 GNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPDKLQEALL 180 GNDIALIKLSRSAQLGDAVQLASLPPAGDILPN+TPCYITGWGRLYTNGPLPDKLQ+A L Sbjct: 121 GNDIALIKLSRSAQLGDAVQLASLPPAGDILPNKTPCYITGWGRLYTNGPLPDKLQQARL 180 Query: 181 PVVDYEHCSRWNWWGSSVKKTMVCAGGDIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVS 240 PVVDY+HCSRWNWWGS+VKKTMVCAGG IRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVS Sbjct: 181 PVVDYKHCSRWNWWGSTVKKTMVCAGGYIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVS 240 Query: 241 AFGCNTRRKPTVFTRVSAFIDWIEETIASH 270 AFGCN KPTVFTRVSAFIDWIEETIASH Sbjct: 241 AFGCNFIWKPTVFTRVSAFIDWIEETIASH 270 >gi|15559207 elastase 2A preproprotein [Homo sapiens] Length = 269 Score = 317 bits (812), Expect = 7e-87 Identities = 157/271 (57%), Positives = 188/271 (69%), Gaps = 4/271 (1%) Query: 2 MLRLLSSLLLVAVASGYGPPSSRPS-SRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGG 60 M+R L LVA A G P+ P +RVV GE+A P SWPWQVSLQY +G +YHTCGG Sbjct: 1 MIRTLLLSTLVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGG 60 Query: 61 SLIAPDWVVTAGHCISSSRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVAC 120 SLIA WV+TA HCISSSRTY+V LG ++ V E + ++ + VH WN + ++ Sbjct: 61 SLIANSWVLTAAHCISSSRTYRVGLGRHNLYVAESGSLAVSVSK--IVVHKDWNSNQISK 118 Query: 121 GNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPDKLQEALL 180 GNDIAL+KL+ L D +QLA LPPAG ILPN PCY+TGWGRL TNG +PD LQ+ L Sbjct: 119 GNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRL 178 Query: 181 PVVDYEHCSRWNWWGSSVKKTMVCAGGD-IRSGCNGDSGGPLNCPTEDGGWQVHGVTSFV 239 VVDY CS WWGSSVK +M+CAGGD + S CNGDSGGPLNC DG WQVHG+ SF Sbjct: 179 LVVDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFG 238 Query: 240 SAFGCNTRRKPTVFTRVSAFIDWIEETIASH 270 S GCN KP+VFTRVS +IDWI IA++ Sbjct: 239 SRLGCNYYHKPSVFTRVSNYIDWINSVIANN 269 >gi|62526043 chymotrypsin C preproprotein [Homo sapiens] Length = 268 Score = 302 bits (774), Expect = 2e-82 Identities = 149/267 (55%), Positives = 190/267 (71%), Gaps = 6/267 (2%) Query: 2 MLRLLSSLLLVAVASGYGPPSSRP--SSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCG 59 ML + L+A AS G PS P S+RVV GEDA P+SWPWQ+SLQY K+ ++ HTCG Sbjct: 1 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG 60 Query: 60 GSLIAPDWVVTAGHCISSSRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVA 119 G+LIA ++V+TA HCIS++RTY+V +G+ + V E E + + + VH WN + Sbjct: 61 GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEV-EDEEGSLFVGVDTIHVHKRWN--ALL 117 Query: 120 CGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPDKLQEAL 179 NDIALIKL+ +L D +Q+A LP +LP + PCY+TGWGRL+TNGP+ DKLQ+ L Sbjct: 118 LRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGL 177 Query: 180 LPVVDYEHCSRWNWWGSSVKKTMVCAGGD-IRSGCNGDSGGPLNCPTEDGGWQVHGVTSF 238 PVVD+ CSR +WWG VKKTMVCAGGD + S CNGDSGGPLNC E+G W+V G+ SF Sbjct: 178 QPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSF 237 Query: 239 VSAFGCNTRRKPTVFTRVSAFIDWIEE 265 S GCNTR+KP V+TRVSA+IDWI E Sbjct: 238 GSRRGCNTRKKPVVYTRVSAYIDWINE 264 >gi|58331211 elastase 2B preproprotein [Homo sapiens] Length = 269 Score = 301 bits (770), Expect = 5e-82 Identities = 148/271 (54%), Positives = 182/271 (67%), Gaps = 4/271 (1%) Query: 2 MLRLLSSLLLVAVASGYGPPSSRPS-SRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGG 60 M+R L LVA A G + P SR++ GE+A P SWPWQVSLQY +G +YHTCGG Sbjct: 1 MIRTLLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGG 60 Query: 61 SLIAPDWVVTAGHCISSSRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVAC 120 SLIA WV+TA HCISSS Y+V+LG+++ V E + ++ + VH WN V+ Sbjct: 61 SLIANSWVLTAAHCISSSGIYRVMLGQHNLYVAESGSLAVSVSK--IVVHKDWNSDQVSK 118 Query: 121 GNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPDKLQEALL 180 GNDIAL+KL+ L D +QLA LPPAG ILPN PCY+TGWGRL TNG LPD L++ L Sbjct: 119 GNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRL 178 Query: 181 PVVDYEHCSRWNWWGSSVKKTMVCAGGD-IRSGCNGDSGGPLNCPTEDGGWQVHGVTSFV 239 VVDY CS WWGS+VK M+CAGGD + CNGDSGGPLNC DG W+VHG+ S Sbjct: 179 LVVDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLT 238 Query: 240 SAFGCNTRRKPTVFTRVSAFIDWIEETIASH 270 S GCN KP++FTRVS + DWI IA++ Sbjct: 239 SVLGCNYYYKPSIFTRVSNYNDWINSVIANN 269 >gi|58331209 chymotrypsin-like elastase family, member 1 [Homo sapiens] Length = 258 Score = 279 bits (714), Expect = 2e-75 Identities = 136/246 (55%), Positives = 173/246 (70%), Gaps = 4/246 (1%) Query: 26 SSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCISSSRTYQVVL 85 ++RVV G +A SWP Q+SLQY GS YHTCGG+LI +WV+TA HC+ +T++VV Sbjct: 16 NARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFRVVA 75 Query: 86 GEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVACGNDIALIKLSRSAQLGDAVQLASLP 145 G+++ + +G EQ + + + VHP WN VA G DIAL++L++S L VQL LP Sbjct: 76 GDHNLSQNDGTEQYVSVQK--IVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLP 133 Query: 146 PAGDILPNETPCYITGWGRLYTNGPLPDKLQEALLPVVDYEHCSRWNWWGSSVKKTMVCA 205 G IL N +PCYITGWG+ TNG L LQ+A LP VDY CS ++WGS+VK TMVCA Sbjct: 134 QEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCA 193 Query: 206 GGD-IRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVSAFGCNTRRKPTVFTRVSAFIDWIE 264 GGD +RSGC GDSGGPL+C +G + VHGVTSFVS+ GCN RKPTVFT+VSA+I WI Sbjct: 194 GGDGVRSGCQGDSGGPLHC-LVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWIN 252 Query: 265 ETIASH 270 IAS+ Sbjct: 253 NVIASN 258 >gi|4503137 chymotrypsin-like [Homo sapiens] Length = 264 Score = 197 bits (501), Expect = 8e-51 Identities = 117/273 (42%), Positives = 155/273 (56%), Gaps = 17/273 (6%) Query: 1 MMLRLLSSLLLVAVASGYGPPSSRP----SSRVVNGEDAVPYSWPWQVSLQYEKSGSFYH 56 ++L L SL+L+ + G G P+ +P S R+VNGE+AV SWPWQVSLQ S +H Sbjct: 2 LLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQ---DSSGFH 58 Query: 57 TCGGSLIAPDWVVTAGHCISSSRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRS 116 CGGSLI+ WVVTA HC S + VVLGEYDR+ P QV+ ++ HP WN + Sbjct: 59 FCGGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRA--ITHPSWNST 116 Query: 117 CVACGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPL-PDKL 175 + ND+ L+KL+ AQ + L + + L C TGWGRL G + P L Sbjct: 117 TM--NNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHL 174 Query: 176 QEALLPVVDYEHCSRWNWWGSSVKKTMVCAGGDIRSGCNGDSGGPLNCPTEDGGWQVHGV 235 Q+ LP+V C + +WGSS+ +M+CAGG S C GDSGGPL C + W + G+ Sbjct: 175 QQVALPLVTVNQCRQ--YWGSSITDSMICAGGAGASSCQGDSGGPLVC-QKGNTWVLIGI 231 Query: 236 TSFVSAFGCNTRRKPTVFTRVSAFIDWIEETIA 268 S+ CN R P V+TRVS F WI + IA Sbjct: 232 VSW-GTKNCNV-RAPAVYTRVSKFSTWINQVIA 262 >gi|118498341 chymotrypsin B1 [Homo sapiens] Length = 263 Score = 193 bits (490), Expect = 2e-49 Identities = 121/274 (44%), Positives = 158/274 (57%), Gaps = 20/274 (7%) Query: 3 LRLLSSLLLVAVASGYGPPSSRPS----SRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTC 58 L LLS LV A G G P+ P SR+VNGEDAVP SWPWQVSLQ +K+G +H C Sbjct: 4 LWLLSCFSLVGAAFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQ-DKTG--FHFC 60 Query: 59 GGSLIAPDWVVTAGHCISSSRTYQVVL-GEYDRAVKEGPEQVIPINSGDLFVHPLWNRSC 117 GGSLI+ DWVVTA HC RT VV+ GE+D+ E QV+ I +F +P + S Sbjct: 61 GGSLISEDWVVTAAHC--GVRTSDVVVAGEFDQGSDEENIQVLKI--AKVFKNPKF--SI 114 Query: 118 VACGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRL-YTNGPLPDKLQ 176 + NDI L+KL+ A+ V LP A D P T C TGWG+ Y PDKLQ Sbjct: 115 LTVNNDITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQ 174 Query: 177 EALLPVVDYEHCSRWNWWGSSVKKTMVCAGGDIRSGCNGDSGGPLNCPTEDGGWQVHGVT 236 +A LP++ C + WG + M+CAG S C GDSGGPL C +DG W + G+ Sbjct: 175 QAALPLLSNAECKK--SWGRRITDVMICAGASGVSSCMGDSGGPLVC-QKDGAWTLVGIV 231 Query: 237 SFVSAFGCNTRRKPTVFTRVSAFIDWIEETIASH 270 S+ S C+T P V+ RV+ I W+++ +A++ Sbjct: 232 SWGSD-TCST-SSPGVYARVTKLIPWVQKILAAN 263 >gi|118498350 chymotrypsin B2 [Homo sapiens] Length = 263 Score = 191 bits (484), Expect = 8e-49 Identities = 119/274 (43%), Positives = 157/274 (57%), Gaps = 20/274 (7%) Query: 3 LRLLSSLLLVAVASGYGPPSSRPS----SRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTC 58 L LLS L+ G G P+ P SR+VNGEDAVP SWPWQVSLQ +K+G +H C Sbjct: 4 LWLLSCWALLGTTFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQ-DKTG--FHFC 60 Query: 59 GGSLIAPDWVVTAGHCISSSRTYQVVL-GEYDRAVKEGPEQVIPINSGDLFVHPLWNRSC 117 GGSLI+ DWVVTA HC RT VV+ GE+D+ E QV+ I +F +P + S Sbjct: 61 GGSLISEDWVVTAAHC--GVRTSDVVVAGEFDQGSDEENIQVLKI--AKVFKNPKF--SI 114 Query: 118 VACGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRL-YTNGPLPDKLQ 176 + NDI L+KL+ A+ V LP A D P T C TGWG+ Y PDKLQ Sbjct: 115 LTVNNDITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQ 174 Query: 177 EALLPVVDYEHCSRWNWWGSSVKKTMVCAGGDIRSGCNGDSGGPLNCPTEDGGWQVHGVT 236 +A LP++ C + WG + M+CAG S C GDSGGPL C +DG W + G+ Sbjct: 175 QAALPLLSNAECKK--SWGRRITDVMICAGASGVSSCMGDSGGPLVC-QKDGAWTLVGIV 231 Query: 237 SFVSAFGCNTRRKPTVFTRVSAFIDWIEETIASH 270 S+ S C+T P V+ RV+ I W+++ +A++ Sbjct: 232 SWGSR-TCST-TTPAVYARVAKLIPWVQKILAAN 263 >gi|4505881 plasminogen [Homo sapiens] Length = 810 Score = 156 bits (394), Expect = 2e-38 Identities = 102/255 (40%), Positives = 137/255 (53%), Gaps = 27/255 (10%) Query: 19 GPPSSRPSS---RVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCI 75 G P P RVV G A P+SWPWQVSL+ H CGG+LI+P+WV+TA HC+ Sbjct: 568 GKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFG---MHFCGGTLISPEWVLTAAHCL 624 Query: 76 SSS---RTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVACGNDIALIKLSRS 132 S +Y+V+LG + E Q I ++ LF+ P DIAL+KLS Sbjct: 625 EKSPRPSSYKVILGAHQEVNLEPHVQEIEVSR--LFLEPT--------RKDIALLKLSSP 674 Query: 133 AQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPL-PDKLQEALLPVVDYEHCSRW 191 A + D V A LP ++ + T C+ITGWG T G L+EA LPV++ + C+R+ Sbjct: 675 AVITDKVIPACLPSPNYVVADRTECFITGWGE--TQGTFGAGLLKEAQLPVIENKVCNRY 732 Query: 192 NWWGSSVKKTMVCAG--GDIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVSAFGCNTRRK 249 + V+ T +CAG C GDSGGPL C +D + + GVTS+ GC K Sbjct: 733 EFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKD-KYILQGVTSW--GLGCARPNK 789 Query: 250 PTVFTRVSAFIDWIE 264 P V+ RVS F+ WIE Sbjct: 790 PGVYVRVSRFVTWIE 804 >gi|11545839 protease, serine, 22 [Homo sapiens] Length = 317 Score = 155 bits (393), Expect = 3e-38 Identities = 105/286 (36%), Positives = 148/286 (51%), Gaps = 37/286 (12%) Query: 2 MLRLLSSLLLVAVASGYGPPSSRPS--SRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCG 59 +L L S+ +L A P +P +RVV GED+ WPW VS+Q K+G+ H C Sbjct: 21 LLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQ--KNGT--HHCA 76 Query: 60 GSLIAPDWVVTAGHCISSSRT----YQVVLGEYD------RAVKEGPEQVIPINSGDLFV 109 GSL+ WV+TA HC + + V+LG + R+ K G V P Sbjct: 77 GSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEP-------- 128 Query: 110 HPLWNRSCVACGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNG 169 HP+++ AC DIAL++L RS Q + V LP A LP T C+I+GWG + Sbjct: 129 HPVYSWKEGACA-DIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGV 187 Query: 170 PL--PDKLQEALLPVVDYEHCSRWNWWGSS---VKKTMVCAG---GDIRSGCNGDSGGPL 221 PL P LQ+ +P++D E CS W G+ + + M+CAG G+ R C GDSGGPL Sbjct: 188 PLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGE-RDACLGDSGGPL 246 Query: 222 NCPTEDGGWQVHGVTSFVSAFGCNTRRKPTVFTRVSAFIDWIEETI 267 C DG W + G+ S+ GC R +P V+ +SA W+E+ + Sbjct: 247 MCQV-DGAWLLAGIISW--GEGCAERNRPGVYISLSAHRSWVEKIV 289 >gi|110815798 ovochymase 1 [Homo sapiens] Length = 1134 Score = 151 bits (382), Expect = 5e-37 Identities = 86/250 (34%), Positives = 140/250 (56%), Gaps = 18/250 (7%) Query: 26 SSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCI---SSSRTYQ 82 S R+ GE+A P+ WPWQV L++ + CGG++I P W++TA HC+ ++ ++ Sbjct: 572 SRRIAGGEEACPHCWPWQVGLRFLGD----YQCGGAIINPVWILTAAHCVQLKNNPLSWT 627 Query: 83 VVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVACGNDIALIKLSRSAQLGDAVQLA 142 ++ G++DR +KE EQV + + VH +N ++ +DIALI+LS + V+ Sbjct: 628 IIAGDHDRNLKESTEQVR--RAKHIIVHEDFNT--LSYDSDIALIQLSSPLEYNSVVRPV 683 Query: 143 SLPPAGDILPNETPCYITGWGRLYTNGPLPDKLQEALLPVVDYEHCSR--WNWWGSSVKK 200 LP + + L + C +TGWG + +G L +LQ+ + V++ E C ++ + + Sbjct: 684 CLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITE 743 Query: 201 TMVCAG---GDIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVSAFGCNTRRKPTVFTRVS 257 M+CAG + C GDSGGPL C E+G + ++G+ S+ GC KP VF RV Sbjct: 744 KMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSW--GAGCVQPWKPGVFARVM 801 Query: 258 AFIDWIEETI 267 F+DWI+ I Sbjct: 802 IFLDWIQSKI 811 Score = 124 bits (311), Expect = 9e-29 Identities = 94/284 (33%), Positives = 138/284 (48%), Gaps = 28/284 (9%) Query: 3 LRLLSSLLLVAVASGYGPPSSRPSSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSL 62 L L + +V + S SR SR+ + ++ PWQVSL+ ++ +H CGGSL Sbjct: 21 LGLKCGIRMVNMKSKEPAVGSRFFSRISSWRNSTVTGHPWQVSLKSDE----HHFCGGSL 76 Query: 63 IAPDWVVTAGHCISSSRTYQ-----VVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSC 117 I D VVTA HC+ S Q V GEY K+ EQ IP++ + HP +N S Sbjct: 77 IQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQNIPVSK--IITHPEYN-SR 133 Query: 118 VACGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPDKLQE 177 DIAL+ L + G+AVQ LP + D + C +GWG++ + LQE Sbjct: 134 EYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSGWGKISKTSEYSNVLQE 193 Query: 178 ALLPVVDYEHCSR--WNWWGSSVKKTMVCAGGDI--RSGCNGDSGGPLNCPTEDGGWQVH 233 LP++D C+ + + +TM+CAG C GDSGGPL C G W + Sbjct: 194 MELPIMDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGDSGGPLVCRRGGGIWILA 253 Query: 234 GVTSFVSAFGCNTRRKPT----------VFTRVSAFIDWIEETI 267 G+TS+V+ GC P +F++VS +D+I + + Sbjct: 254 GITSWVA--GCAGGSVPVRNNHVKASLGIFSKVSELMDFITQNL 295 >gi|33695155 hepsin [Homo sapiens] Length = 417 Score = 148 bits (374), Expect = 4e-36 Identities = 92/259 (35%), Positives = 133/259 (51%), Gaps = 23/259 (8%) Query: 25 PSSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCISSSRT---- 80 P R+V G D WPWQVSL+Y+ + H CGGSL++ DWV+TA HC Sbjct: 159 PVDRIVGGRDTSLGRWPWQVSLRYDGA----HLCGGSLLSGDWVLTAAHCFPERNRVLSR 214 Query: 81 YQVVLGEYDRAVKEGPE---QVIPINSGDLFVHPLWNRSCVACGNDIALIKLSRSAQLGD 137 ++V G +A G + Q + + G L P + + NDIAL+ LS L + Sbjct: 215 WRVFAGAVAQASPHGLQLGVQAVVYHGGYL---PFRDPNSEENSNDIALVHLSSPLPLTE 271 Query: 138 AVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPDKLQEALLPVVDYEHCSRWNWWGSS 197 +Q LP AG L + C +TGWG G LQEA +P++ + C+ +++G+ Sbjct: 272 YIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQ 331 Query: 198 VKKTMVCAG---GDIRSGCNGDSGGPLNCP---TEDGGWQVHGVTSFVSAFGCNTRRKPT 251 +K M CAG G I C GDSGGP C + W++ G+ S+ GC +KP Sbjct: 332 IKPKMFCAGYPEGGI-DACQGDSGGPFVCEDSISRTPRWRLCGIVSW--GTGCALAQKPG 388 Query: 252 VFTRVSAFIDWIEETIASH 270 V+T+VS F +WI + I +H Sbjct: 389 VYTKVSDFREWIFQAIKTH 407 >gi|4504481 hepsin [Homo sapiens] Length = 417 Score = 148 bits (374), Expect = 4e-36 Identities = 92/259 (35%), Positives = 133/259 (51%), Gaps = 23/259 (8%) Query: 25 PSSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCISSSRT---- 80 P R+V G D WPWQVSL+Y+ + H CGGSL++ DWV+TA HC Sbjct: 159 PVDRIVGGRDTSLGRWPWQVSLRYDGA----HLCGGSLLSGDWVLTAAHCFPERNRVLSR 214 Query: 81 YQVVLGEYDRAVKEGPE---QVIPINSGDLFVHPLWNRSCVACGNDIALIKLSRSAQLGD 137 ++V G +A G + Q + + G L P + + NDIAL+ LS L + Sbjct: 215 WRVFAGAVAQASPHGLQLGVQAVVYHGGYL---PFRDPNSEENSNDIALVHLSSPLPLTE 271 Query: 138 AVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPDKLQEALLPVVDYEHCSRWNWWGSS 197 +Q LP AG L + C +TGWG G LQEA +P++ + C+ +++G+ Sbjct: 272 YIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQ 331 Query: 198 VKKTMVCAG---GDIRSGCNGDSGGPLNCP---TEDGGWQVHGVTSFVSAFGCNTRRKPT 251 +K M CAG G I C GDSGGP C + W++ G+ S+ GC +KP Sbjct: 332 IKPKMFCAGYPEGGI-DACQGDSGGPFVCEDSISRTPRWRLCGIVSW--GTGCALAQKPG 388 Query: 252 VFTRVSAFIDWIEETIASH 270 V+T+VS F +WI + I +H Sbjct: 389 VYTKVSDFREWIFQAIKTH 407 >gi|68508970 tryptase beta 2 precursor [Homo sapiens] Length = 275 Score = 146 bits (369), Expect = 2e-35 Identities = 93/282 (32%), Positives = 143/282 (50%), Gaps = 27/282 (9%) Query: 2 MLRLLSSLLLVAVASGYGPPSSRPSSR---VVNGEDAVPYSWPWQVSLQYEKSGSFYHTC 58 ML LL L V + Y P+ + + +V G++A WPWQVSL+ + + H C Sbjct: 1 MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRV-RDRYWMHFC 59 Query: 59 GGSLIAPDWVVTAGHCISSS----RTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWN 114 GGSLI P WV+TA HC+ +V L E ++ Q++P++ + VHP + Sbjct: 60 GGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQD---QLLPVSR--IIVHPQFY 114 Query: 115 RSCVACGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNG--PLP 172 + + G DIAL++L + V +LPPA + P PC++TGWG + + P P Sbjct: 115 TAQI--GADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPP 172 Query: 173 DKLQEALLPVVDYEHCSRWNWWGS-------SVKKTMVCAGGDIRSGCNGDSGGPLNCPT 225 L++ +P+++ C G+ V+ M+CAG R C GDSGGPL C Sbjct: 173 FPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKV 232 Query: 226 EDGGWQVHGVTSFVSAFGCNTRRKPTVFTRVSAFIDWIEETI 267 +G W GV S+ GC +P ++TRV+ ++DWI + Sbjct: 233 -NGTWLQAGVVSW--GEGCAQPNRPGIYTRVTYYLDWIHHYV 271 >gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens] Length = 275 Score = 146 bits (368), Expect = 2e-35 Identities = 94/283 (33%), Positives = 144/283 (50%), Gaps = 29/283 (10%) Query: 2 MLRLLSSLLLVAVASGYGPPSSRPSSR---VVNGEDAVPYSWPWQVSLQYEKSGSFY-HT 57 ML LL L V + Y P+ + + +V G++A WPWQVSL+ G ++ H Sbjct: 1 MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVH--GPYWMHF 58 Query: 58 CGGSLIAPDWVVTAGHCISSS----RTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLW 113 CGGSLI P WV+TA HC+ +V L E ++ Q++P++ + VHP + Sbjct: 59 CGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQD---QLLPVSR--IIVHPQF 113 Query: 114 NRSCVACGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNG--PL 171 + + G DIAL++L + V +LPPA + P PC++TGWG + + P Sbjct: 114 YTAQI--GADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPP 171 Query: 172 PDKLQEALLPVVDYEHCSRWNWWGS-------SVKKTMVCAGGDIRSGCNGDSGGPLNCP 224 P L++ +P+++ C G+ V+ M+CAG R C GDSGGPL C Sbjct: 172 PFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCK 231 Query: 225 TEDGGWQVHGVTSFVSAFGCNTRRKPTVFTRVSAFIDWIEETI 267 +G W GV S+ GC +P ++TRV+ ++DWI + Sbjct: 232 V-NGTWLQAGVVSW--GEGCAQPNRPGIYTRVTYYLDWIHHYV 271 >gi|58218970 protease, serine, 36 [Homo sapiens] Length = 855 Score = 145 bits (365), Expect = 5e-35 Identities = 100/259 (38%), Positives = 133/259 (51%), Gaps = 27/259 (10%) Query: 25 PSSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCISSSRT---- 80 PS+R+V G +A P +WPWQVSL + H CGGSLIAP WV++A HC ++ T Sbjct: 43 PSARIVGGSNAQPGTWPWQVSLHHGGG----HICGGSLIAPSWVLSAAHCFMTNGTLEPA 98 Query: 81 --YQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVACGNDIALIKLSRSAQLGDA 138 + V+LG + + +GP + V P N S V G D+AL++L+ A LG A Sbjct: 99 AEWSVLLGVHSQ---DGPLDGAHTRAVAAIVVPA-NYSQVELGADLALLRLASPASLGPA 154 Query: 139 VQLASLPPAGDILPNETPCYITGWGRLYTNGPLPDK--LQEALLPVVDYEHCS-RWNWWG 195 V LP A + T C+ TGWG + PLP LQE L ++ C ++ G Sbjct: 155 VWPVCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPG 214 Query: 196 S-----SVKKTMVCAG--GDIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVSAFGCNTRR 248 + M+CAG R C GDSGGPL C E G W G+TSF FGC R Sbjct: 215 PFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVC-EEGGRWFQAGITSF--GFGCGRRN 271 Query: 249 KPTVFTRVSAFIDWIEETI 267 +P VFT V+ + WI E + Sbjct: 272 RPGVFTAVATYEAWIREQV 290 Score = 41.6 bits (96), Expect = 7e-04 Identities = 51/233 (21%), Positives = 81/233 (34%), Gaps = 31/233 (13%) Query: 40 WPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCI----SSSRTY-QVVLGEYDRAVKE 94 WPW + C G L+AP WV+ A HC+ S++ Y +V LG + Sbjct: 601 WPWLAEVHVAGD----RVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLP 656 Query: 95 GPEQVIPINSGDLFVHPLWNRSCVACGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNE 154 QV + L R +AL++LS + + L PAG +P Sbjct: 657 QGHQVSRLVISIRLPQHLGLRP------PLALLELSSRVEPSPSALPICLHPAG--IPPG 708 Query: 155 TPCYITGWGRLYTNGPLPDKLQEALLPVVDYEHCSRWNWWGSSVKKTMVCAGGDIRSGCN 214 C++ GW P+ + + D C + G + R C Sbjct: 709 ASCWVLGWKEPQDRVPVAAAVSILTQRICD---CLYQGILPPGTLCVLYAEGQENR--CE 763 Query: 215 GDSGGPLNCPTEDGGWQVHGVTSFVSAFGCNTRRKPTVFTRVSAFIDWIEETI 267 S PL C +G W + G+ + +F + WI +T+ Sbjct: 764 MTSAPPLLCQMTEGSWILVGMA---------VQGSRELFAAIGPEEAWISQTV 807 Score = 38.1 bits (87), Expect = 0.008 Identities = 62/253 (24%), Positives = 97/253 (38%), Gaps = 49/253 (19%) Query: 32 GEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCISSSRT----------Y 81 G+ P +WPW+ + S C G+L++ WV+ C + + Sbjct: 326 GKAPRPGAWPWEAQVMVPGS----RPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAW 381 Query: 82 QVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVACGNDIALIKLSRSAQLGDAVQL 141 +V+L RA E+V + + + W+ + +D+AL++L L A + Sbjct: 382 RVLLPSRPRA-----ERVARLVQHE---NASWDNA-----SDLALLQLRTPVNLSAASRP 428 Query: 142 ASLP-PAGDILPNETPCYITGWGRLYTNGPL--PDKLQEALLPVVDYEHCSRWNWWGSSV 198 LP P LP C + WGR P P L EA L + HC + G++V Sbjct: 429 VCLPHPEHYFLPGSR-CRLARWGR---GEPALGPGALLEAELLGGWWCHC-LYGRQGAAV 483 Query: 199 -----KKTMVCAGGDIR---SGCNGDSGGPLNCPTEDGGWQVHGVTSFVSAFGCNTRRKP 250 +C + C DS L C E+G W + G+ F S GC +P Sbjct: 484 PLPGDPPHALCPAYQEKEEVGSCWNDSRWSLLC-QEEGTWFLAGIRDFPS--GC---LRP 537 Query: 251 TVFTRVSAFIDWI 263 F + WI Sbjct: 538 RAFFPLQTHGPWI 550 >gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens] Length = 2040 Score = 142 bits (358), Expect = 3e-34 Identities = 100/250 (40%), Positives = 133/250 (53%), Gaps = 34/250 (13%) Query: 21 PSSRPSSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCISSSR- 79 P P S +V G A P+SWPWQVSL+ + G H CGG+LI+P+WV+TA HC+ S Sbjct: 1813 PKKCPGS-IVGGCVAHPHSWPWQVSLR-TRFGK--HFCGGTLISPEWVLTAAHCLKKSSR 1868 Query: 80 --TYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVACGNDIALIKLSRSAQLGD 137 +Y+V+LG + E Q I ++ LF+ P DIAL+KLSR A + D Sbjct: 1869 PSSYKVILGAHQEVNLESHVQEIEVSR--LFLEPTQA--------DIALLKLSRPAVITD 1918 Query: 138 AVQLASLPPAGDILPNETPCYITGWGRLYTNGPL-PDKLQEALLPVVDYEHCSRWNWWGS 196 V A LP ++ T CYITGWG T G L+EA L V++ E C+ + + Sbjct: 1919 KVMPACLPSPDYMVTARTECYITGWGE--TQGTFGTGLLKEAQLLVIENEVCNHYKY--- 1973 Query: 197 SVKKTMVCAGGDIR--SGCNGDSGGPLNCPTEDGGWQVHGVTSFVSAFGCNTRRKPTVFT 254 +CA R C GDSGGPL C +D + + GVTS+ GC KP V+ Sbjct: 1974 ------ICAEHLARGTDSCQGDSGGPLVCFEKD-KYILQGVTSW--GLGCARPNKPGVYA 2024 Query: 255 RVSAFIDWIE 264 RVS F+ WIE Sbjct: 2025 RVSRFVTWIE 2034 >gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sapiens] Length = 454 Score = 140 bits (354), Expect = 9e-34 Identities = 84/247 (34%), Positives = 128/247 (51%), Gaps = 21/247 (8%) Query: 26 SSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCISS---SRTYQ 82 SSR+V G ++ WPWQ SLQ++ YH CGGS+I P W++TA HC+ +++ Sbjct: 214 SSRIVGGNMSLLSQWPWQASLQFQG----YHLCGGSVITPLWIITAAHCVYDLYLPKSWT 269 Query: 83 VVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVACGNDIALIKLSRSAQLGDAVQLA 142 + +G P ++ + H + GNDIAL+KL+ + +Q Sbjct: 270 IQVGLVSLLDNPAPSHLVE----KIVYHSKYKPK--RLGNDIALMKLAGPLTFNEMIQPV 323 Query: 143 SLPPAGDILPNETPCYITGWGRLYTN-GPLPDKLQEALLPVVDYEHCSRWNWWGSSVKKT 201 LP + + P+ C+ +GWG G L A +P++ + C+ + +G + + Sbjct: 324 CLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPS 383 Query: 202 MVCAG---GDIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVSAFGCNTRRKPTVFTRVSA 258 M+CAG G + S C GDSGGPL C E W++ G TSF GC KP V+TRV++ Sbjct: 384 MLCAGYLTGGVDS-CQGDSGGPLVC-QERRLWKLVGATSF--GIGCAEVNKPGVYTRVTS 439 Query: 259 FIDWIEE 265 F+DWI E Sbjct: 440 FLDWIHE 446 >gi|4506153 prostasin preproprotein [Homo sapiens] Length = 343 Score = 139 bits (351), Expect = 2e-33 Identities = 89/261 (34%), Positives = 129/261 (49%), Gaps = 24/261 (9%) Query: 20 PPSSRPSSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCISSSR 79 P P +R+ G AV WPWQVS+ YE H CGGSL++ WV++A HC S Sbjct: 36 PCGVAPQARITGGSSAVAGQWPWQVSITYEG----VHVCGGSLVSEQWVLSAAHCFPSEH 91 Query: 80 ---TYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVACGNDIALIKLSRSAQLG 136 Y+V LG + +V + D+ HP + + DIAL++LSR Sbjct: 92 HKEAYEVKLGAHQLDSYSEDAKVSTLK--DIIPHPSYLQE--GSQGDIALLQLSRPITFS 147 Query: 137 DAVQLASLPPAGDILPNETPCYITGWGRLYTNGPL--PDKLQEALLPVVDYEHCS-RWNW 193 ++ LP A PN C +TGWG + + L P LQ+ +P++ E C+ +N Sbjct: 148 RYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNI 207 Query: 194 WGSS-----VKKTMVCAG--GDIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVSAFGCNT 246 V++ MVCAG + C GDSGGPL+CP E G W + G+ S+ A C Sbjct: 208 DAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVE-GLWYLTGIVSWGDA--CGA 264 Query: 247 RRKPTVFTRVSAFIDWIEETI 267 R +P V+T S++ WI+ + Sbjct: 265 RNRPGVYTLASSYASWIQSKV 285 >gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] Length = 247 Score = 137 bits (346), Expect = 8e-33 Identities = 100/265 (37%), Positives = 134/265 (50%), Gaps = 26/265 (9%) Query: 9 LLLVAVASGYGPPSSRPSSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWV 68 L+L VA+ P ++V G + S P+QVSL S YH CGGSLI WV Sbjct: 5 LILTFVAAALAAPFD-DDDKIVGGYNCEENSVPYQVSLN-----SGYHFCGGSLINEQWV 58 Query: 69 VTAGHCISSSRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVACGNDIALIK 128 V+AGHC S QV LGE++ V EG EQ IN+ + HP ++R + NDI LIK Sbjct: 59 VSAGHCYKS--RIQVRLGEHNIEVLEGNEQF--INAAKIIRHPQYDRKTL--NNDIMLIK 112 Query: 129 LSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNG-PLPDKLQEALLPVVDYEH 187 LS A + V SLP A T C I+GWG ++G PD+LQ PV+ Sbjct: 113 LSSRAVINARVSTISLPTAPP--ATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAK 170 Query: 188 CSRWNWWGSSVKKTMVCAG--GDIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVSAFGCN 245 C + + M C G + C GDSGGP+ C Q+ GV S+ GC Sbjct: 171 CEA--SYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVC-----NGQLQGVVSW--GDGCA 221 Query: 246 TRRKPTVFTRVSAFIDWIEETIASH 270 + KP V+T+V ++ WI+ TIA++ Sbjct: 222 QKNKPGVYTKVYNYVKWIKNTIAAN 246 >gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] Length = 638 Score = 136 bits (343), Expect = 2e-32 Identities = 91/257 (35%), Positives = 133/257 (51%), Gaps = 22/257 (8%) Query: 22 SSRPSSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCISSS--- 78 +++ S+R+V G ++ WPWQVSLQ + + H CGGSLI WV+TA HC Sbjct: 384 TTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQ-RHLCGGSLIGHQWVLTAAHCFDGLPLQ 442 Query: 79 ---RTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVACGN-DIALIKLSRSAQ 134 R Y +L D K+ P I ++ +H + V+ GN DIALIKL Sbjct: 443 DVWRIYSGILNLSD-ITKDTPFSQIK----EIIIHQNYK---VSEGNHDIALIKLQAPLN 494 Query: 135 LGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPDKLQEALLPVVDYEHCSRWNWW 194 + + LP GD T C++TGWG G + + LQ+ +P+V E C + + Sbjct: 495 YTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQK-RYQ 553 Query: 195 GSSVKKTMVCAG--GDIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVSAFGCNTRRKPTV 252 + + MVCAG + C GDSGGPL C +G W++ G+TS+ GC R +P V Sbjct: 554 DYKITQRMVCAGYKEGGKDACKGDSGGPLVC-KHNGMWRLVGITSW--GEGCARREQPGV 610 Query: 253 FTRVSAFIDWIEETIAS 269 +T+V+ ++DWI E S Sbjct: 611 YTKVAEYMDWILEKTQS 627 >gi|148231605 ovochymase 2 [Homo sapiens] Length = 564 Score = 136 bits (343), Expect = 2e-32 Identities = 90/258 (34%), Positives = 126/258 (48%), Gaps = 26/258 (10%) Query: 27 SRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCISSSR---TYQV 83 SR++ G S+PWQVSL+ + H CGGS+++P WV+TA HCI++ T V Sbjct: 50 SRILGGSQVEKGSYPWQVSLKQRQK----HICGGSIVSPQWVITAAHCIANRNIVSTLNV 105 Query: 84 VLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVACGNDIALIKLSRSAQLGDAVQLAS 143 GEYD + + EQ + I + + +HP ++ DIAL+K++ + Q G V Sbjct: 106 TAGEYDLSQTDPGEQTLTIET--VIIHPHFSTK-KPMDYDIALLKMAGAFQFGHFVGPIC 162 Query: 144 LPPAGDILPNETPCYITGWGRLYTNGPLPDKLQEALLPVVDYEHC--SRWNWWGSSVKKT 201 LP + C GWGRL G L LQE LP++ +E C + KT Sbjct: 163 LPELREQFEAGFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKT 222 Query: 202 MVCAG--GDIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVSAFGC------NTRR----K 249 +C G R C GDSGG L C + G W + GVTS+ GC N R+ Sbjct: 223 FLCTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSW--GLGCGRGWRNNVRKSDQGS 280 Query: 250 PTVFTRVSAFIDWIEETI 267 P +FT +S + WI E I Sbjct: 281 PGIFTDISKVLPWIHEHI 298 >gi|117956391 protease, serine, 33 [Homo sapiens] Length = 280 Score = 136 bits (342), Expect = 2e-32 Identities = 94/279 (33%), Positives = 132/279 (47%), Gaps = 30/279 (10%) Query: 9 LLLVAVASGYGPPSS-----RPSSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLI 63 LL++ A G S+ R SSR+V G D WPWQ S+Q+ + H CGGSLI Sbjct: 12 LLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGA----HVCGGSLI 67 Query: 64 APDWVVTAGHCI---SSSRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVAC 120 AP WV+TA HC + Y+V LG +P+ + + P ++ Sbjct: 68 APQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRR--VLLPPDYSED--GA 123 Query: 121 GNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPD--KLQEA 178 D+AL++L R L VQ LP G P TPC +TGWG L PLP+ LQ Sbjct: 124 RGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGV 183 Query: 179 LLPVVDYEHCSRWNWWGSSVKKT-------MVCAG--GDIRSGCNGDSGGPLNCPTEDGG 229 +P++D C G+ V + +CAG + C GDSGGPL C + G Sbjct: 184 RVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTC-LQSGS 242 Query: 230 WQVHGVTSFVSAFGCNTRRKPTVFTRVSAFIDWIEETIA 268 W + GV S+ GC +P V+T V+ + WI+ ++ Sbjct: 243 WVLVGVVSW--GKGCALPNRPGVYTSVATYSPWIQARVS 279 >gi|170932492 transmembrane protease, serine 5 [Homo sapiens] Length = 457 Score = 135 bits (341), Expect = 3e-32 Identities = 85/253 (33%), Positives = 128/253 (50%), Gaps = 21/253 (8%) Query: 23 SRP-SSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCISSSR-- 79 +RP +SR+V G+ P WPWQ S+ F HTCGGS++AP WVVTA HC+ S R Sbjct: 211 ARPLASRIVGGQSVAPGRWPWQASVAL----GFRHTCGGSVLAPRWVVTAAHCMHSFRLA 266 Query: 80 ---TYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVACGNDIALIKLSRSAQLG 136 +++V G + P Q + + HPL+ S D+AL++L + Sbjct: 267 RLSSWRVHAGLVSHSAVR-PHQGALVER--IIPHPLY--SAQNHDYDVALLRLQTALNFS 321 Query: 137 DAVQLASLPPAGDILPNETPCYITGWGRLYTNGPL-PDKLQEALLPVVDYEHCSRWNWWG 195 D V LP P + C+++GWG + + D LQ+ ++P+ + C+ + Sbjct: 322 DTVGAVCLPAKEQHFPKGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLFSTQLCNSSCVYS 381 Query: 196 SSVKKTMVCAG--GDIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVSAFGCNTRRKPTVF 253 ++ M+CAG C GDSGGPL CP D W++ GV S+ GC P V+ Sbjct: 382 GALTPRMLCAGYLDGRADACQGDSGGPLVCPDGD-TWRLVGVVSW--GRGCAEPNHPGVY 438 Query: 254 TRVSAFIDWIEET 266 +V+ F+DWI +T Sbjct: 439 AKVAEFLDWIHDT 451 >gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] Length = 321 Score = 135 bits (339), Expect = 5e-32 Identities = 96/277 (34%), Positives = 133/277 (48%), Gaps = 22/277 (7%) Query: 1 MMLRLLSSLLLVAVASGYGPPS-SRPSSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCG 59 ++L + + L + G G P S R+V G A +WPWQ SL+ + H CG Sbjct: 9 LLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRR----VHVCG 64 Query: 60 GSLIAPDWVVTAGHCIS---SSRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRS 116 GSL++P WV+TA HC S +S YQV LGE + + V + +H + Sbjct: 65 GSLLSPQWVLTAAHCFSGSLNSSDYQVHLGELEITLSPHFSTV-----RQIILHSSPSGQ 119 Query: 117 CVACGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPD--K 174 G DIAL++LS L + LP A D C++TGWG PLP Sbjct: 120 PGTSG-DIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYS 178 Query: 175 LQEALLPVVDYEHCSR--WNWWGSSVKKTMVCAGGDIRSGCNGDSGGPLNCPTEDGGWQV 232 L+E + VVD E C R GS ++ M+CA G C DSGGPL C +G W Sbjct: 179 LREVKVSVVDTETCRRDYPGPGGSILQPDMLCARGP-GDACQDDSGGPLVCQV-NGAWVQ 236 Query: 233 HGVTSFVSAFGCNTRRKPTVFTRVSAFIDWIEETIAS 269 G+ S+ GC +P V+TRV A+++WI I + Sbjct: 237 AGIVSW--GEGCGRPNRPGVYTRVPAYVNWIRRHITA 271 >gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] Length = 247 Score = 134 bits (338), Expect = 6e-32 Identities = 97/265 (36%), Positives = 137/265 (51%), Gaps = 26/265 (9%) Query: 9 LLLVAVASGYGPPSSRPSSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWV 68 L+L VA+ P ++V G S P+QVSL S YH CGGSLI+ WV Sbjct: 5 LILTFVAAAVAAPFD-DDDKIVGGYICEENSVPYQVSLN-----SGYHFCGGSLISEQWV 58 Query: 69 VTAGHCISSSRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVACGNDIALIK 128 V+AGHC S QV LGE++ V EG EQ IN+ + HP +N + NDI LIK Sbjct: 59 VSAGHCYKS--RIQVRLGEHNIEVLEGNEQF--INAAKIIRHPKYNSRTL--DNDILLIK 112 Query: 129 LSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNG-PLPDKLQEALLPVVDYEH 187 LS A + V SLP A E+ I+GWG ++G PD+LQ PV+ Sbjct: 113 LSSPAVINSRVSAISLPTAPPAAGTES--LISGWGNTLSSGADYPDELQCLDAPVLSQAE 170 Query: 188 CSRWNWWGSSVKKTMVCAG--GDIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVSAFGCN 245 C + + M C G + C GDSGGP+ +G ++ G+ S+ +GC Sbjct: 171 CEA--SYPGKITNNMFCVGFLEGGKDSCQGDSGGPV---VSNG--ELQGIVSW--GYGCA 221 Query: 246 TRRKPTVFTRVSAFIDWIEETIASH 270 + +P V+T+V ++DWI++TIA++ Sbjct: 222 QKNRPGVYTKVYNYVDWIKDTIAAN 246 >gi|4503627 coagulation factor XI precursor [Homo sapiens] Length = 625 Score = 134 bits (338), Expect = 6e-32 Identities = 82/243 (33%), Positives = 126/243 (51%), Gaps = 14/243 (5%) Query: 28 RVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHC---ISSSRTYQVV 84 R+V G +V WPWQV+L + S + H CGGS+I W++TA HC + S + +V Sbjct: 387 RIVGGTASVRGEWPWQVTL-HTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVY 445 Query: 85 LGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVACGNDIALIKLSRSAQLGDAVQLASL 144 G +++ E E ++ +H + + G DIAL+KL + D+ + L Sbjct: 446 SGILNQS--EIKEDTSFFGVQEIIIHDQYKMA--ESGYDIALLKLETTVNYTDSQRPICL 501 Query: 145 PPAGDILPNETPCYITGWGRLYTNGPLPDKLQEALLPVVDYEHCSRWNWWGSSVKKTMVC 204 P GD T C++TGWG + + LQ+A +P+V E C + + G + M+C Sbjct: 502 PSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQK-RYRGHKITHKMIC 560 Query: 205 AG--GDIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVSAFGCNTRRKPTVFTRVSAFIDW 262 AG + C GDSGGPL+C + W + G+TS+ GC R +P V+T V ++DW Sbjct: 561 AGYREGGKDACKGDSGGPLSCKHNE-VWHLVGITSW--GEGCAQRERPGVYTNVVEYVDW 617 Query: 263 IEE 265 I E Sbjct: 618 ILE 620 >gi|29244926 corin [Homo sapiens] Length = 1042 Score = 134 bits (338), Expect = 6e-32 Identities = 89/254 (35%), Positives = 135/254 (53%), Gaps = 20/254 (7%) Query: 21 PSSRPSSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCI---SS 77 P++R + R++ G + P WPWQ SLQ E SG H CG LIA WV+T HC + Sbjct: 794 PAARMNKRILGGRTSRPGRWPWQCSLQSEPSG---HICGCVLIAKKWVLTVAHCFEGREN 850 Query: 78 SRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVACGNDIALIKLSRSAQLGD 137 + ++VVLG + Q + + + +HP ++R+ V DI++++LS Sbjct: 851 AAVWKVVLGINNLDHPSVFMQTRFVKT--IILHPRYSRAVV--DYDISIVELSEDISETG 906 Query: 138 AVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPDKLQEALLPVVDYEHCSRWNWWGSS 197 V+ LP L +T CYITGWG + +P KLQE + ++ EHC + + + Sbjct: 907 YVRPVCLPNPEQWLEPDTYCYITGWGHM--GNKMPFKLQEGEVRIISLEHCQSY-FDMKT 963 Query: 198 VKKTMVCAG---GDIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVSAFGCNTR-RKPTVF 253 + M+CAG G + S C GDSGGPL C G W + G+TS+ S C ++ P V+ Sbjct: 964 ITTRMICAGYESGTVDS-CMGDSGGPLVCEKPGGRWTLFGLTSWGSV--CFSKVLGPGVY 1020 Query: 254 TRVSAFIDWIEETI 267 + VS F++WI+ I Sbjct: 1021 SNVSYFVEWIKRQI 1034 >gi|194018492 transmembrane protease, serine 11F [Homo sapiens] Length = 438 Score = 133 bits (334), Expect = 2e-31 Identities = 87/267 (32%), Positives = 138/267 (51%), Gaps = 17/267 (6%) Query: 2 MLRLLSSLLLVAVASGYGP-PSSRPSSRVVNG-EDAVPYSWPWQVSLQYEKSGSFYHTCG 59 M LL+S + + S P P+S + R+V G E A+ WPWQ SLQ SG H CG Sbjct: 178 MRNLLNSRCGIRMTSSNMPLPASSSTQRIVQGRETAMEGEWPWQASLQLIGSG---HQCG 234 Query: 60 GSLIAPDWVVTAGHCISSSRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVA 119 SLI+ W++TA HC ++ + + + + N + +H ++R Sbjct: 235 ASLISNTWLLTAAHCFWKNKDPTQWIATFGATITP---PAVKRNVRKIILHENYHRETNE 291 Query: 120 CGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPDKLQEAL 179 NDIAL++LS + + VQ LP + LP +T ++TG+G + +GP+ + L++A Sbjct: 292 --NDIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFGSIVDDGPIQNTLRQAR 349 Query: 180 LPVVDYEHCSRWNWWGSSVKKTMVCAG---GDIRSGCNGDSGGPLNCPTEDGGWQVHGVT 236 + + + C+R + + + M+CAG G I C GDSGGPL D W + G+ Sbjct: 350 VETISTDVCNRKDVYDGLITPGMLCAGFMEGKI-DACKGDSGGPLVYDNHD-IWYIVGIV 407 Query: 237 SFVSAFGCNTRRKPTVFTRVSAFIDWI 263 S+ + C +KP V+TRV+ + DWI Sbjct: 408 SWGQS--CALPKKPGVYTRVTKYRDWI 432 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.136 0.448 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,642,143 Number of Sequences: 37866 Number of extensions: 542021 Number of successful extensions: 1888 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 155 Number of HSP's successfully gapped in prelim test: 21 Number of HSP's that attempted gapping in prelim test: 1163 Number of HSP's gapped (non-prelim): 197 length of query: 270 length of database: 18,247,518 effective HSP length: 101 effective length of query: 169 effective length of database: 14,423,052 effective search space: 2437495788 effective search space used: 2437495788 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.