Search of human proteins with 6679189

Search of human proteins with 6679189

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|6679189 transmembrane emp24 domain containing 3 [Homo
sapiens]
         (217 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6679189 transmembrane emp24 domain containing 3 [Homo sapiens]     439   e-124
gi|32996709 transmembrane emp24 protein transport domain contain...   287   5e-78
gi|19923442 transmembrane emp24 protein transport domain contain...   101   4e-22
gi|5803149 coated vesicle membrane protein [Homo sapiens]             101   4e-22
gi|5803040 interleukin 1 receptor-like 1 ligand precursor [Homo ...   100   1e-21
gi|39725636 transmembrane emp24 protein transport domain contain...    70   2e-12
gi|33457308 transmembrane emp24 protein transport domain contain...    67   1e-11
gi|98986464 transmembrane emp24 domain-containing protein 10 pre...    59   4e-09
gi|21389573 transmembrane emp24 protein transport domain contain...    45   5e-05
gi|105990514 filamin B, beta (actin binding protein 278) [Homo s...    31   0.92 
gi|157671915 guanylate binding protein family, member 6 [Homo sa...    30   1.2  
gi|223005929 hypothetical protein LOC284071 [Homo sapiens]             29   2.7  
gi|4502819 cholinergic receptor, muscarinic 3 [Homo sapiens]           29   3.5  
gi|157502195 proteasome 26S non-ATPase subunit 13 isoform 2 [Hom...    29   3.5  
gi|157502193 proteasome 26S non-ATPase subunit 13 isoform 1 [Hom...    29   3.5  
gi|195972879 transmembrane protein 194A isoform b [Homo sapiens]       28   6.0  

>gi|6679189 transmembrane emp24 domain containing 3 [Homo sapiens]
          Length = 217

 Score =  439 bits (1129), Expect = e-124
 Identities = 217/217 (100%), Positives = 217/217 (100%)

Query: 1   MGSTVPRSASVLLLLLLLRRAEQPCGAELTFELPDNAKQCFHEEVEQGVKFSLDYQVITG 60
           MGSTVPRSASVLLLLLLLRRAEQPCGAELTFELPDNAKQCFHEEVEQGVKFSLDYQVITG
Sbjct: 1   MGSTVPRSASVLLLLLLLRRAEQPCGAELTFELPDNAKQCFHEEVEQGVKFSLDYQVITG 60

Query: 61  GHYDVDCYVEDPQGNTIYRETKKQYDSFTYRAEVKGVYQFCFSNEFSTFSHKTVYFDFQV 120
           GHYDVDCYVEDPQGNTIYRETKKQYDSFTYRAEVKGVYQFCFSNEFSTFSHKTVYFDFQV
Sbjct: 61  GHYDVDCYVEDPQGNTIYRETKKQYDSFTYRAEVKGVYQFCFSNEFSTFSHKTVYFDFQV 120

Query: 121 GDEPPILPDMGNRVTALTQMESACVTIHEALKTVIDSQTHYRLREAQDRARAEDLNSRVS 180
           GDEPPILPDMGNRVTALTQMESACVTIHEALKTVIDSQTHYRLREAQDRARAEDLNSRVS
Sbjct: 121 GDEPPILPDMGNRVTALTQMESACVTIHEALKTVIDSQTHYRLREAQDRARAEDLNSRVS 180

Query: 181 YWSVGETIALFVVSFSQVLLLKSFFTEKRPISRAVHS 217
           YWSVGETIALFVVSFSQVLLLKSFFTEKRPISRAVHS
Sbjct: 181 YWSVGETIALFVVSFSQVLLLKSFFTEKRPISRAVHS 217


>gi|32996709 transmembrane emp24 protein transport domain containing
           7 [Homo sapiens]
          Length = 224

 Score =  287 bits (734), Expect = 5e-78
 Identities = 140/205 (68%), Positives = 167/205 (81%), Gaps = 2/205 (0%)

Query: 14  LLLLLRRAEQPCGA-ELTFELPDNAKQCFHEEVEQGVKFSLDYQVITGGHYDVDCYVEDP 72
           LL LL     P GA E+TFELPDNAKQCF+E++ QG K +L++QVITGGHYDVDC +EDP
Sbjct: 21  LLALLLLVPGPGGASEITFELPDNAKQCFYEDIAQGTKCTLEFQVITGGHYDVDCRLEDP 80

Query: 73  QGNTIYRETKKQYDSFTYRAEVKGVYQFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMGN 132
            G  +Y+E KKQYDSFT+ A   G Y+FCFSNEFSTF+HKTVYFDFQVG++PP+ P   N
Sbjct: 81  DGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHKTVYFDFQVGEDPPLFPS-EN 139

Query: 133 RVTALTQMESACVTIHEALKTVIDSQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFV 192
           RV+ALTQMESACV+IHEALK+VID QTH+RLREAQ R+RAEDLN+RV+YWSVGE + L V
Sbjct: 140 RVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLV 199

Query: 193 VSFSQVLLLKSFFTEKRPISRAVHS 217
           VS  QV LLKSFF++KR  +  V S
Sbjct: 200 VSIGQVFLLKSFFSDKRTTTTRVGS 224


>gi|19923442 transmembrane emp24 protein transport domain containing
           5 [Homo sapiens]
          Length = 229

 Score =  101 bits (252), Expect = 4e-22
 Identities = 60/193 (31%), Positives = 96/193 (49%), Gaps = 11/193 (5%)

Query: 27  AELTFELPDNAKQCFHEEVEQGVKFSLDYQVITGGHYDVDCYVEDPQGNTIYRETKKQYD 86
           ++ TF LP   K+CF++ +       ++YQV+ G   D+D ++  P+G T+  E +K   
Sbjct: 34  SDFTFTLPAGQKECFYQPMPLKASLEIEYQVLDGAGLDIDFHLASPEGKTLVFEQRKSDG 93

Query: 87  SFTYRAEVKGVYQFCFSNEFSTFSHKTVYFDF---QVGDEPPILPDMGNRVTALTQMESA 143
             T   EV G Y FCF N FST S K ++F+     +G++     D    +T    ++  
Sbjct: 94  VHTVETEV-GDYMFCFDNTFSTISEKVIFFELILDNMGEQAQEQEDWKKYITGTDILDMK 152

Query: 144 CVTIHEALKTVIDS-------QTHYRLREAQDRARAEDLNSRVSYWSVGETIALFVVSFS 196
              I E++ ++          Q   R  EA+DR   E    RV++WS+   + + VVS  
Sbjct: 153 LEDILESINSIKSRLSKSGHIQILLRAFEARDRNIQESNFDRVNFWSMVNLVVMVVVSAI 212

Query: 197 QVLLLKSFFTEKR 209
           QV +LKS F +KR
Sbjct: 213 QVYMLKSLFEDKR 225


>gi|5803149 coated vesicle membrane protein [Homo sapiens]
          Length = 201

 Score =  101 bits (252), Expect = 4e-22
 Identities = 57/176 (32%), Positives = 87/176 (49%), Gaps = 2/176 (1%)

Query: 36  NAKQCFHEEVEQGVKFSLDYQVITGGHYDVDCYVEDPQGNTIYRETKKQYDSFTYRAEVK 95
           +A++CF E V  G K  L ++V  GG  D+D  +  P    IY+  ++    +T+ A + 
Sbjct: 28  HAEECFFERVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMD 87

Query: 96  GVYQFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMGNRVTALTQMESACVTIHEALKTVI 155
           G Y+FCFSN  ST + K V F   +G E P   DM        ++E     +  A+  V 
Sbjct: 88  GTYKFCFSNRMSTMTPKIVMFTIDIG-EAPKGQDMETEAHQ-NKLEEMINELAVAMTAVK 145

Query: 156 DSQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLLKSFFTEKRPI 211
             Q +  +RE   RA  ++ NSRV  WS  E + L  ++  Q+  LK FF  +R +
Sbjct: 146 HEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 201


>gi|5803040 interleukin 1 receptor-like 1 ligand precursor [Homo
           sapiens]
          Length = 227

 Score =  100 bits (248), Expect = 1e-21
 Identities = 64/193 (33%), Positives = 89/193 (46%), Gaps = 9/193 (4%)

Query: 28  ELTFELPDNAKQCFHEEVEQGVKFSLDYQVITGGHYDVDCYVEDPQGNTIYRETKKQYDS 87
           E TF LP   KQCF++          +YQVI G   DVD  +E PQG  +  E++K    
Sbjct: 33  EFTFLLPAGRKQCFYQSAPANASLETEYQVIGGAGLDVDFTLESPQGVLLVSESRKADGV 92

Query: 88  FTYRAEVKGVYQFCFSNEFSTFSHKTVYFD--FQVGDEPPILPDMGNRVTALTQMESACV 145
            T      G Y+ CF N FST S K V+F+  F    +   +      V     ++    
Sbjct: 93  HTVEPTEAGDYKLCFDNSFSTISEKLVFFELIFDSLQDDEEVEGWAEAVEPEEMLDVKME 152

Query: 146 TIHEALKTV-------IDSQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQV 198
            I E+++T+       I   T  R  EA+DR   E    RV++WS      L +V+  QV
Sbjct: 153 DIKESIETMRTRLERSIQMLTLLRAFEARDRNLQEGNLERVNFWSAVNVAVLLLVAVLQV 212

Query: 199 LLLKSFFTEKRPI 211
             LK FF +KRP+
Sbjct: 213 CTLKRFFQDKRPV 225


>gi|39725636 transmembrane emp24 protein transport domain containing
           9 [Homo sapiens]
          Length = 235

 Score = 69.7 bits (169), Expect = 2e-12
 Identities = 60/225 (26%), Positives = 100/225 (44%), Gaps = 23/225 (10%)

Query: 2   GSTVPRSASVLLLLLLLRRAEQPCGAELTFELPDNAKQCFHEEVEQGV------------ 49
           G+ + R    LLL+L L       G+ L F + +  K+CF EE+                
Sbjct: 15  GTGLGRVMRTLLLVLWLATR----GSALYFHIGETEKKCFIEEIPDETMVIGNYRTQLYD 70

Query: 50  KFSLDYQVITGGHYDVDCYVEDPQGNTIYRETKKQYDSFTYRAEVKGVYQFCF---SNEF 106
           K   +YQ  T G   +   V+DP+   I          FT+ +   G +Q C    S +F
Sbjct: 71  KQREEYQPATPG-LGMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKF 129

Query: 107 STFSHKT--VYFDFQVGDEPPILPDMGNRVTALTQMESACVTIHEALKTVIDSQTHYRLR 164
           S F+     V+ D QVG+      ++  +   L++++     + E ++ +   Q + R R
Sbjct: 130 SLFAGGMLRVHLDIQVGEHANDYAEIAAK-DKLSELQLRVRQLVEQVEQIQKEQNYQRWR 188

Query: 165 EAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLLKSFFTEKR 209
           E + R  +E  N RV +WS+ +T+ L  +   Q+  LKSFF  K+
Sbjct: 189 EERFRQTSESTNQRVLWWSILQTLILVAIGVWQMRHLKSFFEAKK 233


>gi|33457308 transmembrane emp24 protein transport domain containing
           4 [Homo sapiens]
          Length = 227

 Score = 67.0 bits (162), Expect = 1e-11
 Identities = 55/214 (25%), Positives = 92/214 (42%), Gaps = 21/214 (9%)

Query: 12  LLLLLLLRRAEQPCGAELTFELPDNAKQCFHEEVEQGVKFSLDY---------QVITGGH 62
           LLLL L     Q     L F + +  K+CF EE+        +Y         +V     
Sbjct: 17  LLLLALCATGAQG----LYFHIGETEKRCFIEEIPDETMVIGNYRTQMWDKQKEVFLPST 72

Query: 63  YDVDCYVE--DPQGNTIYRETKKQYDSFTYRAEVKGVYQFCF---SNEFSTFS--HKTVY 115
             +  +VE  DP G  +          FT+ +   G +Q C    S   + F+     V+
Sbjct: 73  PGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVH 132

Query: 116 FDFQVGDEPPILPDMGNRVTALTQMESACVTIHEALKTVIDSQTHYRLREAQDRARAEDL 175
            D QVG+     P++  +   LT+++     + + ++ +   Q + R RE + R  +E  
Sbjct: 133 LDIQVGEHANNYPEIAAK-DKLTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSEST 191

Query: 176 NSRVSYWSVGETIALFVVSFSQVLLLKSFFTEKR 209
           N RV +WS+ +T+ L +    Q+  LKSFF  K+
Sbjct: 192 NQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKK 225


>gi|98986464 transmembrane emp24 domain-containing protein 10
           precursor [Homo sapiens]
          Length = 219

 Score = 58.5 bits (140), Expect = 4e-09
 Identities = 48/211 (22%), Positives = 99/211 (46%), Gaps = 10/211 (4%)

Query: 6   PRSASVLLLLLLLRRAEQPCGAELTFELPDNAKQCFHEEVEQGVKFSLDYQVI--TGGHY 63
           P   ++LLL LL  R        ++F LP N+++C  EE+ + +  +  Y++   +GG  
Sbjct: 13  PFPLALLLLFLLGPRLV----LAISFHLPINSRKCLREEIHKDLLVTGAYEISDQSGGAG 68

Query: 64  DVDCYVE--DPQGNTIYRETKKQYDSFTYRAEVKGVYQFCFSNEFS-TFSHKTVYFDFQV 120
            +  +++  D  G+ +Y +       F +  E   +++ CF ++ +     + V  D + 
Sbjct: 69  GLRSHLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKH 128

Query: 121 GDEPPILPDMGNRVTALTQMESACVTIHEALKTVIDSQTHYRLREAQDRARAEDLNSRVS 180
           G E     ++  +V  L  +E     + +  +++++   + + RE + R   E  N+RV 
Sbjct: 129 GVEAKNYEEIA-KVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVL 187

Query: 181 YWSVGETIALFVVSFSQVLLLKSFFTEKRPI 211
           Y+S+     L  ++  QV  L+ FF  K+ I
Sbjct: 188 YFSIFSMFCLIGLATWQVFYLRRFFKAKKLI 218


>gi|21389573 transmembrane emp24 protein transport domain containing
           6 [Homo sapiens]
          Length = 240

 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 41/184 (22%), Positives = 74/184 (40%), Gaps = 15/184 (8%)

Query: 33  LPDNAKQCFHEEVEQG--VKFSLDYQVITGGHYD--VDCYVEDPQGNTIYRETKKQYDSF 88
           +P    +CF +   Q     FS + Q   G  +D  V     +PQG  I   ++      
Sbjct: 48  IPPGGTECFWQFAHQTGYFYFSCEVQRTVGMSHDRHVAATAHNPQGFLI-DTSQGVRGQI 106

Query: 89  TYRAEVKGVYQFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMGNRVTALTQMESACVTIH 148
            +  +  G YQ C SN+ + F    VY +F V  E    P+  ++     Q+      I 
Sbjct: 107 NFSTQETGFYQLCLSNQHNHFGSVQVYLNFGVFYEG---PETDHKQKERKQLNDTLDAIE 163

Query: 149 EALKTVIDSQTHY-------RLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLL 201
           +  + V ++  H        R+R+  D    +   + V++WS  +++ + +    Q+  L
Sbjct: 164 DGTQKVQNNIFHMWRYYNFARMRKMADFFLIQSNYNYVNWWSTAQSLVIILSGILQLYFL 223

Query: 202 KSFF 205
           K  F
Sbjct: 224 KRLF 227


>gi|105990514 filamin B, beta (actin binding protein 278) [Homo
           sapiens]
          Length = 2602

 Score = 30.8 bits (68), Expect = 0.92
 Identities = 22/61 (36%), Positives = 33/61 (54%), Gaps = 9/61 (14%)

Query: 45  VEQGVKFSLDYQVITGGHYDVDCYVEDPQGN------TIYRETKKQYDSFTYRAEVKGVY 98
           V+Q  KF++D   I+ G  DV  +VEDP+GN      T   +  K Y S  Y  +V G++
Sbjct: 271 VKQPAKFTVD--TISAGQGDVMVFVEDPEGNKEEAQVTPDSDKNKTY-SVEYLPKVTGLH 327

Query: 99  Q 99
           +
Sbjct: 328 K 328


>gi|157671915 guanylate binding protein family, member 6 [Homo
           sapiens]
          Length = 633

 Score = 30.4 bits (67), Expect = 1.2
 Identities = 25/104 (24%), Positives = 42/104 (40%), Gaps = 5/104 (4%)

Query: 72  PQGNTIYRETKKQYDSFTYRAEVKGVYQFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMG 131
           P G+ +Y ETK++ +   ++   KGV        F  F    +  +  +      L D  
Sbjct: 429 PGGHKLYMETKERIEQDYWQVPRKGVKA---KEVFQRFLESQMVIEESILQSDKALTDRE 485

Query: 132 NRVTALTQMESACVTIHEALKTVIDSQTHYRLREAQDRARAEDL 175
             V      + A     E LK  +  Q   +  EAQD++R E++
Sbjct: 486 KAVAVDRAKKEAAEKEQELLKQKLQEQ--QQQMEAQDKSRKENI 527


>gi|223005929 hypothetical protein LOC284071 [Homo sapiens]
          Length = 825

 Score = 29.3 bits (64), Expect = 2.7
 Identities = 17/71 (23%), Positives = 29/71 (40%), Gaps = 2/71 (2%)

Query: 26 GAELTFELPDNAKQCFHEEVEQGVKFS--LDYQVITGGHYDVDCYVEDPQGNTIYRETKK 83
          G E     P  A +C++   + G + +      ++TG     DCY    + N   R+T  
Sbjct: 21 GLEPKVAFPGGANRCWNLGADAGSRLTDVFGSVMLTGSASFYDCYTSQSEDNVDLRQTYT 80

Query: 84 QYDSFTYRAEV 94
           + S  Y + V
Sbjct: 81 PFSSTEYSSSV 91


>gi|4502819 cholinergic receptor, muscarinic 3 [Homo sapiens]
          Length = 590

 Score = 28.9 bits (63), Expect = 3.5
 Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 5/53 (9%)

Query: 157 SQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLLKSFFTEKR 209
           S+   +L  A D A+  D+NS     SVG++ A   +SF +  L K F  + R
Sbjct: 425 SKLPIQLESAVDTAKTSDVNS-----SVGKSTATLPLSFKEATLAKRFALKTR 472


>gi|157502195 proteasome 26S non-ATPase subunit 13 isoform 2 [Homo
           sapiens]
          Length = 378

 Score = 28.9 bits (63), Expect = 3.5
 Identities = 13/38 (34%), Positives = 22/38 (57%)

Query: 17  LLRRAEQPCGAELTFELPDNAKQCFHEEVEQGVKFSLD 54
           LLR+ +  C  E+TF  P N +Q   EE+ +  K +++
Sbjct: 270 LLRKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKITVN 307


>gi|157502193 proteasome 26S non-ATPase subunit 13 isoform 1 [Homo
           sapiens]
          Length = 376

 Score = 28.9 bits (63), Expect = 3.5
 Identities = 13/38 (34%), Positives = 22/38 (57%)

Query: 17  LLRRAEQPCGAELTFELPDNAKQCFHEEVEQGVKFSLD 54
           LLR+ +  C  E+TF  P N +Q   EE+ +  K +++
Sbjct: 268 LLRKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKITVN 305


>gi|195972879 transmembrane protein 194A isoform b [Homo sapiens]
          Length = 371

 Score = 28.1 bits (61), Expect = 6.0
 Identities = 13/58 (22%), Positives = 30/58 (51%), Gaps = 1/58 (1%)

Query: 155 IDSQTHYRLREAQDRARAEDLN-SRVSYWSVGETIALFVVSFSQVLLLKSFFTEKRPI 211
           ++S    R+ + ++  + ++L  S++ Y+S G T+ +       + +L  F  +K PI
Sbjct: 87  VNSSRLVRVTQVENEEKLKELEQSQIFYYSTGMTVGIVASLLIIIFILSKFMPKKSPI 144


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.134    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,734,260
Number of Sequences: 37866
Number of extensions: 311677
Number of successful extensions: 639
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 617
Number of HSP's gapped (non-prelim): 17
length of query: 217
length of database: 18,247,518
effective HSP length: 98
effective length of query: 119
effective length of database: 14,536,650
effective search space: 1729861350
effective search space used: 1729861350
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.