BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|66773030 solute carrier family 1, member 1 [Homo sapiens] (524 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|66773030 solute carrier family 1, member 1 [Homo sapiens] 1006 0.0 gi|169790839 solute carrier family 1 (glial high affinity glutam... 509 e-144 gi|40254478 excitatory amino acid transporter 2 [Homo sapiens] 495 e-140 gi|4827012 solute carrier family 1 (high affinity aspartate/glut... 491 e-139 gi|194239697 solute carrier family 1 (glutamate transporter), me... 462 e-130 gi|21314632 solute carrier family 1, member 4 isoform 1 [Homo sa... 395 e-110 gi|5032093 solute carrier family 1 member 5 isoform 1 [Homo sapi... 391 e-109 gi|223468566 solute carrier family 1 member 5 isoform 3 [Homo sa... 292 4e-79 gi|207444683 solute carrier family 1, member 4 isoform 2 [Homo s... 290 3e-78 gi|223468564 solute carrier family 1 member 5 isoform 2 [Homo sa... 287 2e-77 gi|222418639 melanoma antigen family B, 2 [Homo sapiens] 34 0.29 gi|148228829 G protein-coupled receptor 1 [Homo sapiens] 32 1.1 gi|36951012 G protein-coupled receptor 1 [Homo sapiens] 32 1.1 gi|156151371 Kruppel-like factor 3 (basic) [Homo sapiens] 31 2.4 gi|199559490 Abelson helper integration site 1 isoform a [Homo s... 30 4.1 gi|199559438 Abelson helper integration site 1 isoform a [Homo s... 30 4.1 gi|31542701 Abelson helper integration site 1 isoform a [Homo sa... 30 4.1 gi|42476325 solute carrier family 18 (vesicular monoamine), memb... 30 5.4 gi|169206294 PREDICTED: hypothetical protein [Homo sapiens] 30 7.0 gi|113424485 PREDICTED: hypothetical protein [Homo sapiens] 30 7.0 gi|20162572 necdin-like 2 [Homo sapiens] 30 7.0 gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 29 9.2 gi|24371241 zinc finger, DHHC-type containing 14 isoform 1 [Homo... 29 9.2 gi|24371272 zinc finger, DHHC-type containing 14 isoform 2 [Homo... 29 9.2 >gi|66773030 solute carrier family 1, member 1 [Homo sapiens] Length = 524 Score = 1006 bits (2602), Expect = 0.0 Identities = 524/524 (100%), Positives = 524/524 (100%) Query: 1 MGKPARKGCEWKRFLKNNWVLLSTVAAVVLGITTGVLVREHSNLSTLEKFYFAFPGEILM 60 MGKPARKGCEWKRFLKNNWVLLSTVAAVVLGITTGVLVREHSNLSTLEKFYFAFPGEILM Sbjct: 1 MGKPARKGCEWKRFLKNNWVLLSTVAAVVLGITTGVLVREHSNLSTLEKFYFAFPGEILM 60 Query: 61 RMLKLIILPLIISSMITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGV 120 RMLKLIILPLIISSMITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGV Sbjct: 61 RMLKLIILPLIISSMITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGV 120 Query: 121 TQKVGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQACFQQYKTKREEVKPPSDPEMNMT 180 TQKVGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQACFQQYKTKREEVKPPSDPEMNMT Sbjct: 121 TQKVGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQACFQQYKTKREEVKPPSDPEMNMT 180 Query: 181 EESFTAVMTTAISKNKTKEYKIVGMYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFF 240 EESFTAVMTTAISKNKTKEYKIVGMYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFF Sbjct: 181 EESFTAVMTTAISKNKTKEYKIVGMYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFF 240 Query: 241 NALSDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWEIFRKLGLYMATVLTGLAIHSIVI 300 NALSDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWEIFRKLGLYMATVLTGLAIHSIVI Sbjct: 241 NALSDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWEIFRKLGLYMATVLTGLAIHSIVI 300 Query: 301 LPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLP 360 LPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLP Sbjct: 301 LPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLP 360 Query: 361 VGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMV 420 VGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMV Sbjct: 361 VGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMV 420 Query: 421 IVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELEQMDVSSEVN 480 IVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELEQMDVSSEVN Sbjct: 421 IVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELEQMDVSSEVN 480 Query: 481 IVNPFALESTILDNEDSDTKKSYVNGGFAVDKSDTISFTQTSQF 524 IVNPFALESTILDNEDSDTKKSYVNGGFAVDKSDTISFTQTSQF Sbjct: 481 IVNPFALESTILDNEDSDTKKSYVNGGFAVDKSDTISFTQTSQF 524 >gi|169790839 solute carrier family 1 (glial high affinity glutamate transporter), member 3 [Homo sapiens] Length = 542 Score = 509 bits (1312), Expect = e-144 Identities = 272/495 (54%), Positives = 361/495 (72%), Gaps = 7/495 (1%) Query: 12 KRFLKNNWVLLSTVAAVVLGITTGVLVREHSNLSTLEKFYFAFPGEILMRMLKLIILPLI 71 K +L N +L TV AV++G G +R + +S E YF+FPGE+LMRML++++LPLI Sbjct: 42 KSYLFRNAFVLLTVTAVIVGTILGFTLRPY-RMSYREVKYFSFPGELLMRMLQMLVLPLI 100 Query: 72 ISSMITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVGEIARTG 131 ISS++TG+AALDS SGK+G+RAVVYY TT+IAV++GI++V+ I PG K + R G Sbjct: 101 ISSLVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKEN-MHREG 159 Query: 132 STPEVSTVDAMLDLIRNMFPENLVQACFQQYKTKREE--VKPPSDPEMNMTEESFTAVMT 189 V+ DA LDLIRNMFP NLV+ACF+Q+KT E+ K P + V Sbjct: 160 KIVRVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSE 219 Query: 190 TAISKNK-TKEYKIVGMYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATM 248 + + T+E V +G+N LGL+VF + FG VIG M E+GQ L +FF++L++A M Sbjct: 220 AMETLTRITEELVPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIM 279 Query: 249 KIVQIIMCYMPLGILFLIAGKIIEVEDWEIFR-KLGLYMATVLTGLAIHSIVILPLIYFI 307 ++V +IM Y P+GILFLIAGKI+E+ED + +L +Y TV+ GL IH++++LPL+YF+ Sbjct: 280 RLVAVIMWYAPVGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFL 339 Query: 308 VVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLPVGATINM 367 V RKNP+ F G+ QAL+TAL SSSSATLP+TF+C EENN VDKR+TRFVLPVGATINM Sbjct: 340 VTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINM 399 Query: 368 DGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVG 427 DGTALYEA+AA+FIAQ+N+ +L GQIITISITAT+ASIGAAG+PQAGLVTMVIVL++VG Sbjct: 400 DGTALYEALAAIFIAQVNNFELNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVG 459 Query: 428 LPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELEQMDVSSEVNIVNPFAL 487 LP +D+TLIIAVDW LDR RT NVLGD+ G GIVE LS+ EL+ DV +++ + Sbjct: 460 LPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEM 519 Query: 488 ESTI-LDNEDSDTKK 501 + L +D++T+K Sbjct: 520 KKPYQLIAQDNETEK 534 >gi|40254478 excitatory amino acid transporter 2 [Homo sapiens] Length = 574 Score = 495 bits (1274), Expect = e-140 Identities = 262/471 (55%), Positives = 343/471 (72%), Gaps = 5/471 (1%) Query: 15 LKNNWVLLSTVAAVVLGITTGVLVREHSNLSTLEKFYFAFPGEILMRMLKLIILPLIISS 74 L N +L TV V+LG G L+R S + AFPG+ILMRMLK++ILPLIISS Sbjct: 41 LGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISS 100 Query: 75 MITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVGEIARTGSTP 134 +ITG++ LD+ SG++G RA+VYY TT+IA +LG++LV++I PG + ++ Sbjct: 101 LITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKND 160 Query: 135 EVSTVDAMLDLIRNMFPENLVQACFQQYKT--KREEVKPPSDPEMNMTEESFTAVMTTAI 192 EVS++DA LDLIRN+FPENLVQACFQQ +T K+ V PP D E N T + + T Sbjct: 161 EVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPPDEEANATSAVVSLLNETVT 220 Query: 193 S-KNKTKEYKIVGM-YSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKI 250 +TK G+ + DG+NVLGLI F + FG+ +GKMG++ +++VDFFN L++ MK+ Sbjct: 221 EVPEETKMVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKL 280 Query: 251 VQIIMCYMPLGILFLIAGKIIEVEDWEIF-RKLGLYMATVLTGLAIHSIVILPLIYFIVV 309 V +IM Y PLGI LI GKII ++D E+ R+LG+YM TV+ GL IH + LPLIYF+V Sbjct: 281 VIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVT 340 Query: 310 RKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLPVGATINMDG 369 RKNPF F G+ QA +TAL +SS+ TLPVTFRC EEN +DKR+TRFVLPVGATINMDG Sbjct: 341 RKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDG 400 Query: 370 TALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLP 429 TALYEAVAA+FIAQ+N + L GQI+T+S+TAT AS+GAA +P AGLVTM+++L+AVGLP Sbjct: 401 TALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLP 460 Query: 430 AEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELEQMDVSSEVN 480 ED++L++AVDWLLDR RT VNV+GD+FG GIV LSK EL+ +D V+ Sbjct: 461 TEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVH 511 >gi|4827012 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 [Homo sapiens] Length = 564 Score = 491 bits (1265), Expect = e-139 Identities = 262/480 (54%), Positives = 351/480 (73%), Gaps = 23/480 (4%) Query: 13 RFLKNNWVLLSTVAAVVLGITTGVLVREHSNLSTLEKFYFAFPGEILMRMLKLIILPLII 72 RFL+ N +L TV+AVV+G++ +R + L+ + YF+FPGE+LMRML++++LPLI+ Sbjct: 51 RFLRRNAFILLTVSAVVIGVSLAFALRPYQ-LTYRQIKYFSFPGELLMRMLQMLVLPLIV 109 Query: 73 SSMITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVGEIARTGS 132 SS++TG+A+LD+ +G++G+RA VYY TT+IAV +GI++V I PG K G + R G Sbjct: 110 SSLVTGMASLDNKATGRMGMRAAVYYMVTTIIAVFIGILMVTIIHPGKGSKEG-LHREGR 168 Query: 133 TPEVSTVDAMLDLIRNMFPENLVQACFQQYKTK-------REEVK-----------PPSD 174 + T DA +DLIRNMFP NLV+ACF+Q+KT+ R V+ PP Sbjct: 169 IETIPTADAFMDLIRNMFPPNLVEACFKQFKTQYSTRVVTRTMVRTENGSEPGASMPPPF 228 Query: 175 PEMNMTE--ESFTAVMTTAISKNKTKEYKIVGMYSDGINVLGLIVFCLVFGLVIGKMGEK 232 N T E+ T + T +E V ++GIN LGL+VF + FGLVIG M K Sbjct: 229 SVENGTSFLENVTRALGTLQEMLSFEETVPVPGSANGINALGLVVFSVAFGLVIGGMKHK 288 Query: 233 GQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWEIFR-KLGLYMATVLT 291 G++L DFF++L++A M++V II+ Y P+GILFLIAGKI+E+ED + +LG+Y TV+ Sbjct: 289 GRVLRDFFDSLNEAIMRLVGIIIWYAPVGILFLIAGKILEMEDMAVLGGQLGMYTLTVIV 348 Query: 292 GLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVD 351 GL +H+ ++LPLIYF+V +NPF F GM QAL+TA+ SSSSATLP+TFRC EE VD Sbjct: 349 GLFLHAGIVLPLIYFLVTHRNPFPFIGGMLQALITAMGTSSSSATLPITFRCLEEGLGVD 408 Query: 352 KRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGV 411 +RITRFVLPVGAT+NMDGTALYEA+AA+FIAQ+N+ +L +GQI TISITAT+AS+GAAG+ Sbjct: 409 RRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISITATAASVGAAGI 468 Query: 412 PQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKELE 471 PQAGLVTMVIVL++VGLP ED+TLIIAVDW LDR RTM NVLGD+ G ++E LS++ELE Sbjct: 469 PQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHLSQRELE 528 >gi|194239697 solute carrier family 1 (glutamate transporter), member 7 [Homo sapiens] Length = 560 Score = 462 bits (1188), Expect = e-130 Identities = 247/468 (52%), Positives = 330/468 (70%), Gaps = 16/468 (3%) Query: 16 KNNWVLLSTVAAVVLGITTGVLVREHSNLSTLEKFYFAFPGEILMRMLKLIILPLIISSM 75 + N +L+ +V +V++G G +R LS E YF FPGE+LMRMLK++ILPL++SS+ Sbjct: 15 RRNGLLILSVLSVIVGCLLGFFLRTR-RLSPQEISYFQFPGELLMRMLKMMILPLVVSSL 73 Query: 76 ITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVGEIARTGSTPE 135 ++G+A+LD+ S ++G+ V YY TT +AVI+GI +V I PG + ++G P Sbjct: 74 MSGLASLDAKTSSRLGVLTVAYYLWTTFMAVIVGIFMVSIIHPGSAAQKETTEQSGK-PI 132 Query: 136 VSTVDAMLDLIRNMFPENLVQACFQQYKTKREEV--KPPSDPE---------MNMTEESF 184 +S+ DA+LDLIRNMFP NLV+A F+QY+TK V P PE + EE+ Sbjct: 133 MSSADALLDLIRNMFPANLVEATFKQYRTKTTPVVKSPKVAPEEAPPRRILIYGVQEENG 192 Query: 185 TAVMTTAISKNKTKE--YKIVGMYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNA 242 + V A+ E YK SDG+NVLG++ F G+++G+MG+ G LV F Sbjct: 193 SHVQNFALDLTPPPEVVYKSEPGTSDGMNVLGIVFFSATMGIMLGRMGDSGAPLVSFCQC 252 Query: 243 LSDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWE-IFRKLGLYMATVLTGLAIHSIVIL 301 L+++ MKIV + + Y P GI+FLIAGKI+E++D + +KLG Y TV+ GL +H + IL Sbjct: 253 LNESVMKIVAVAVWYFPFGIVFLIAGKILEMDDPRAVGKKLGFYSVTVVCGLVLHGLFIL 312 Query: 302 PLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLPV 361 PL+YF + +KNP F G+ QALL AL SSSSATLP+TF+C ENN +D+RI RFVLPV Sbjct: 313 PLLYFFITKKNPIVFIRGILQALLIALATSSSSATLPITFKCLLENNHIDRRIARFVLPV 372 Query: 362 GATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVI 421 GATINMDGTALYEAVAA+FIAQ+N+ +L GQIITISITAT+ASIGAAG+PQAGLVTMVI Sbjct: 373 GATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVI 432 Query: 422 VLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKKE 469 VL++VGLP +D+TLIIAVDW LDRFRTM+NVLGDA GI+ + +K+ Sbjct: 433 VLTSVGLPTDDITLIIAVDWALDRFRTMINVLGDALAAGIMAHICRKD 480 >gi|21314632 solute carrier family 1, member 4 isoform 1 [Homo sapiens] Length = 532 Score = 395 bits (1015), Expect = e-110 Identities = 212/462 (45%), Positives = 302/462 (65%), Gaps = 26/462 (5%) Query: 14 FLKNNWVLLSTVAAVVLGITTGVLVREHSNLSTLEKFYFAFPGEILMRMLKLIILPLIIS 73 FL+ ++L TV+ V+ G G +R S LS + Y AFPGE+L+RML++IILPL++ Sbjct: 38 FLRRQALVLLTVSGVLAGAGLGAALRGLS-LSRTQVTYLAFPGEMLLRMLRMIILPLVVC 96 Query: 74 SMITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGV---TQKVGEIART 130 S+++G A+LD++ G++G AV Y+ TTL A L + L IKPG T + ++ Sbjct: 97 SLVSGAASLDASCLGRLGGIAVAYFGLTTLSASALAVALAFIIKPGSGAQTLQSSDLGLE 156 Query: 131 GSTPEV---STVDAMLDLIRNMFPENLVQACFQQYKTKREEVKPPSDPEMNMTEESFTAV 187 S P TVD+ LDL RN+FP NLV A F+ Y T + V Sbjct: 157 DSGPPPVPKETVDSFLDLARNLFPSNLVVAAFRTYAT------------------DYKVV 198 Query: 188 MTTAISKNKTKEYKIVGMYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDAT 247 + S N T E +G +G+N+LGL++F LV G+ + K+G +G+ L+ FFN+L++AT Sbjct: 199 TQNSSSGNVTHEKIPIGTEIEGMNILGLVLFALVLGVALKKLGSEGEDLIRFFNSLNEAT 258 Query: 248 MKIVQIIMCYMPLGILFLIAGKIIEVEDWEIF-RKLGLYMATVLTGLAIHSIVILPLIYF 306 M +V IM Y+P+GI+FL+ KI+E++D + LG Y+ + G IH ++LPLIYF Sbjct: 259 MVLVSWIMWYVPVGIMFLVGSKIVEMKDIIVLVTSLGKYIFASILGHVIHGGIVLPLIYF 318 Query: 307 IVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLPVGATIN 366 + RKNPFRF +G+ TA SSSATLP +C EENN VDKRI+RF+LP+GAT+N Sbjct: 319 VFTRKNPFRFLLGLLAPFATAFATCSSSATLPSMMKCIEENNGVDKRISRFILPIGATVN 378 Query: 367 MDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAV 426 MDG A+++ VAAVFIAQLN+++L GQI TI +TAT++S+GAAGVP G++T+ I+L A+ Sbjct: 379 MDGAAIFQCVAAVFIAQLNNVELNAGQIFTILVTATASSVGAAGVPAGGVLTIAIILEAI 438 Query: 427 GLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKK 468 GLP D+ LI+AVDW++DR T+VNV GDA G GI+ L++K Sbjct: 439 GLPTHDLPLILAVDWIVDRTTTVVNVEGDALGAGILHHLNQK 480 >gi|5032093 solute carrier family 1 member 5 isoform 1 [Homo sapiens] Length = 541 Score = 391 bits (1004), Expect = e-109 Identities = 212/483 (43%), Positives = 309/483 (63%), Gaps = 38/483 (7%) Query: 12 KRFLKNNWVLLSTVAAVVLGITTGVLVREHSNLSTL---EKFYFAFPGEILMRMLKLIIL 68 +R L+ N ++L TV AVV G+ G+ V L F FPGE+L+R+L++IIL Sbjct: 46 RRCLRANLLVLLTVVAVVAGVALGLGVSGAGGALALGPERLSAFVFPGELLLRLLRMIIL 105 Query: 69 PLIISSMITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPG-----VTQK 123 PL++ S+I G A+LD G++G A++++ TTL+A LG+ L ++++PG + Sbjct: 106 PLVVCSLIGGAASLDPGALGRLGAWALLFFLVTTLLASALGVGLALALQPGAASAAINAS 165 Query: 124 VGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQACFQQYKTKREEVKPPSDPEMNMTEES 183 VG + P +D+ LDL RN+FP NLV A F+ Y T EE N+T Sbjct: 166 VGAAGSAENAPSKEVLDSFLDLARNIFPSNLVSAAFRSYSTTYEE--------RNITG-- 215 Query: 184 FTAVMTTAISKNKTKEYKIVGMYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNAL 243 T+ VG +G+N+LGL+VF +VFG+ + K+G +G++L+ FFN+ Sbjct: 216 -------------TRVKVPVGQEVEGMNILGLVVFAIVFGVALRKLGPEGELLIRFFNSF 262 Query: 244 SDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWEI-FRKLGLYMATVLTGLAIHSIVILP 302 ++ATM +V IM Y P+GI+FL+AGKI+E+ED + F +LG Y+ L G AIH +++LP Sbjct: 263 NEATMVLVSWIMWYAPVGIMFLVAGKIVEMEDVGLLFARLGKYILCCLLGHAIHGLLVLP 322 Query: 303 LIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLPVG 362 LIYF+ RKNP+RF G+ L TA SSSSATLP+ +C EENN V K I+RF+LP+G Sbjct: 323 LIYFLFTRKNPYRFLWGIVTPLATAFGTSSSSATLPLMMKCVEENNGVAKHISRFILPIG 382 Query: 363 ATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIV 422 AT+NMDG AL++ VAAVFIAQL+ L +IITI +TAT++S+GAAG+P G++T+ I+ Sbjct: 383 ATVNMDGAALFQCVAAVFIAQLSQQSLDFVKIITILVTATASSVGAAGIPAGGVLTLAII 442 Query: 423 LSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKK------ELEQMDVS 476 L AV LP + ++LI+AVDWL+DR T++NV GDA G G+++ + E E + V Sbjct: 443 LEAVNLPVDHISLILAVDWLVDRSCTVLNVEGDALGAGLLQNYVDRTESRSTEPELIQVK 502 Query: 477 SEV 479 SE+ Sbjct: 503 SEL 505 >gi|223468566 solute carrier family 1 member 5 isoform 3 [Homo sapiens] Length = 339 Score = 292 bits (748), Expect = 4e-79 Identities = 145/284 (51%), Positives = 207/284 (72%), Gaps = 7/284 (2%) Query: 203 VGMYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGI 262 VG +G+N+LGL+VF +VFG+ + K+G +G++L+ FFN+ ++ATM +V IM Y P+GI Sbjct: 20 VGQEVEGMNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNEATMVLVSWIMWYAPVGI 79 Query: 263 LFLIAGKIIEVEDWEI-FRKLGLYMATVLTGLAIHSIVILPLIYFIVVRKNPFRFAMGMA 321 +FL+AGKI+E+ED + F +LG Y+ L G AIH +++LPLIYF+ RKNP+RF G+ Sbjct: 80 MFLVAGKIVEMEDVGLLFARLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIV 139 Query: 322 QALLTALMISSSSATLPVTFRCAEENNQVDKRITRFVLPVGATINMDGTALYEAVAAVFI 381 L TA SSSSATLP+ +C EENN V K I+RF+LP+GAT+NMDG AL++ VAAVFI Sbjct: 140 TPLATAFGTSSSSATLPLMMKCVEENNGVAKHISRFILPIGATVNMDGAALFQCVAAVFI 199 Query: 382 AQLNDLDLGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDW 441 AQL+ L +IITI +TAT++S+GAAG+P G++T+ I+L AV LP + ++LI+AVDW Sbjct: 200 AQLSQQSLDFVKIITILVTATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDW 259 Query: 442 LLDRFRTMVNVLGDAFGTGIVEKLSKK------ELEQMDVSSEV 479 L+DR T++NV GDA G G+++ + E E + V SE+ Sbjct: 260 LVDRSCTVLNVEGDALGAGLLQNYVDRTESRSTEPELIQVKSEL 303 >gi|207444683 solute carrier family 1, member 4 isoform 2 [Homo sapiens] Length = 312 Score = 290 bits (741), Expect = 3e-78 Identities = 138/260 (53%), Positives = 195/260 (75%), Gaps = 1/260 (0%) Query: 210 INVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGK 269 +N+LGL++F LV G+ + K+G +G+ L+ FFN+L++ATM +V IM Y+P+GI+FL+ K Sbjct: 1 MNILGLVLFALVLGVALKKLGSEGEDLIRFFNSLNEATMVLVSWIMWYVPVGIMFLVGSK 60 Query: 270 IIEVEDWEIF-RKLGLYMATVLTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTAL 328 I+E++D + LG Y+ + G IH ++LPLIYF+ RKNPFRF +G+ TA Sbjct: 61 IVEMKDIIVLVTSLGKYIFASILGHVIHGGIVLPLIYFVFTRKNPFRFLLGLLAPFATAF 120 Query: 329 MISSSSATLPVTFRCAEENNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLD 388 SSSATLP +C EENN VDKRI+RF+LP+GAT+NMDG A+++ VAAVFIAQLN+++ Sbjct: 121 ATCSSSATLPSMMKCIEENNGVDKRISRFILPIGATVNMDGAAIFQCVAAVFIAQLNNVE 180 Query: 389 LGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRT 448 L GQI TI +TAT++S+GAAGVP G++T+ I+L A+GLP D+ LI+AVDW++DR T Sbjct: 181 LNAGQIFTILVTATASSVGAAGVPAGGVLTIAIILEAIGLPTHDLPLILAVDWIVDRTTT 240 Query: 449 MVNVLGDAFGTGIVEKLSKK 468 +VNV GDA G GI+ L++K Sbjct: 241 VVNVEGDALGAGILHHLNQK 260 >gi|223468564 solute carrier family 1 member 5 isoform 2 [Homo sapiens] Length = 313 Score = 287 bits (734), Expect = 2e-77 Identities = 142/277 (51%), Positives = 203/277 (73%), Gaps = 7/277 (2%) Query: 210 INVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGK 269 +N+LGL+VF +VFG+ + K+G +G++L+ FFN+ ++ATM +V IM Y P+GI+FL+AGK Sbjct: 1 MNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNEATMVLVSWIMWYAPVGIMFLVAGK 60 Query: 270 IIEVEDWEI-FRKLGLYMATVLTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTAL 328 I+E+ED + F +LG Y+ L G AIH +++LPLIYF+ RKNP+RF G+ L TA Sbjct: 61 IVEMEDVGLLFARLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIVTPLATAF 120 Query: 329 MISSSSATLPVTFRCAEENNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLD 388 SSSSATLP+ +C EENN V K I+RF+LP+GAT+NMDG AL++ VAAVFIAQL+ Sbjct: 121 GTSSSSATLPLMMKCVEENNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLSQQS 180 Query: 389 LGIGQIITISITATSASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRT 448 L +IITI +TAT++S+GAAG+P G++T+ I+L AV LP + ++LI+AVDWL+DR T Sbjct: 181 LDFVKIITILVTATASSVGAAGIPAGGVLTLAIILEAVNLPVDHISLILAVDWLVDRSCT 240 Query: 449 MVNVLGDAFGTGIVEKLSKK------ELEQMDVSSEV 479 ++NV GDA G G+++ + E E + V SE+ Sbjct: 241 VLNVEGDALGAGLLQNYVDRTESRSTEPELIQVKSEL 277 >gi|222418639 melanoma antigen family B, 2 [Homo sapiens] Length = 319 Score = 34.3 bits (77), Expect = 0.29 Identities = 55/222 (24%), Positives = 82/222 (36%), Gaps = 39/222 (17%) Query: 73 SSMITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVLVVSIKPGVTQKVGEIARTGS 132 SS ++G AA S +G + TT A G+ S K G GE + S Sbjct: 42 SSSVSGGAASSSPAAG---IPQEPQRAPTTAAAAAAGVSSTKS-KKGAKSHQGEKNASSS 97 Query: 133 TPEVSTVDAMLDLIRNMFPENLVQACFQQYKTKREEVKPPSDPEMNMTEESFTAVMTTAI 192 ST D + +LVQ +YK K+ K M + Sbjct: 98 QASTSTKSPSEDPLTRK-SGSLVQFLLYKYKIKKSVTK---------------GEMLKIV 141 Query: 193 SKNKTKEY-KIVGMYSDGINVLGLIVFCLVFGLVIGKMGEKGQI--------LVDFFNAL 243 K + + +I+ S+G++V VFGL + K+ G L D + L Sbjct: 142 GKRFREHFPEILKKASEGLSV--------VFGLELNKVNPNGHTYTFIDKVDLTDEESLL 193 Query: 244 SDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWEIFRKLGLY 285 S +++M LG++FL E E WE LG+Y Sbjct: 194 SSWDFPRRKLLMPL--LGVIFLNGNSATEEEIWEFLNMLGVY 233 >gi|148228829 G protein-coupled receptor 1 [Homo sapiens] Length = 355 Score = 32.3 bits (72), Expect = 1.1 Identities = 33/146 (22%), Positives = 60/146 (41%), Gaps = 30/146 (20%) Query: 213 LGLIVFCLVFGLVIGKMGEKGQILVD---FFNALSDATMKIVQIIMCYMPLGILFLIAGK 269 + + CL+F + +K IL+ F+ L + +V ++C+ P + + Sbjct: 222 MSICYLCLIFKV------KKRSILISSRHFWTIL----VVVVAFVVCWTPYHLFSI---- 267 Query: 270 IIEVEDWEIFRKLGLYMATVL-------TGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQ 322 WE+ Y V+ TGLA + + P++Y ++ +K RF +A+ Sbjct: 268 ------WELTIHHNSYSHHVMQAGIPLSTGLAFLNSCLNPILYVLISKKFQARFRSSVAE 321 Query: 323 ALLTALMISSSSATLPVTFRCAEENN 348 L L S S T+ R +E N Sbjct: 322 ILKYTLWEVSCSGTVSEQLRNSETKN 347 >gi|36951012 G protein-coupled receptor 1 [Homo sapiens] Length = 355 Score = 32.3 bits (72), Expect = 1.1 Identities = 33/146 (22%), Positives = 60/146 (41%), Gaps = 30/146 (20%) Query: 213 LGLIVFCLVFGLVIGKMGEKGQILVD---FFNALSDATMKIVQIIMCYMPLGILFLIAGK 269 + + CL+F + +K IL+ F+ L + +V ++C+ P + + Sbjct: 222 MSICYLCLIFKV------KKRSILISSRHFWTIL----VVVVAFVVCWTPYHLFSI---- 267 Query: 270 IIEVEDWEIFRKLGLYMATVL-------TGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQ 322 WE+ Y V+ TGLA + + P++Y ++ +K RF +A+ Sbjct: 268 ------WELTIHHNSYSHHVMQAGIPLSTGLAFLNSCLNPILYVLISKKFQARFRSSVAE 321 Query: 323 ALLTALMISSSSATLPVTFRCAEENN 348 L L S S T+ R +E N Sbjct: 322 ILKYTLWEVSCSGTVSEQLRNSETKN 347 >gi|156151371 Kruppel-like factor 3 (basic) [Homo sapiens] Length = 345 Score = 31.2 bits (69), Expect = 2.4 Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 4/58 (6%) Query: 286 MATVLTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALM----ISSSSATLPV 339 MA L+ I S ILP+I +VV+ PF + + Q L+ +L SSSS +PV Sbjct: 127 MAAALSRHGIRSPGILPVIQPVVVQPVPFMYTSHLQQPLMVSLSEEMENSSSSMQVPV 184 >gi|199559490 Abelson helper integration site 1 isoform a [Homo sapiens] Length = 1196 Score = 30.4 bits (67), Expect = 4.1 Identities = 16/55 (29%), Positives = 29/55 (52%), Gaps = 2/55 (3%) Query: 150 FPENLV--QACFQQYKTKREEVKPPSDPEMNMTEESFTAVMTTAISKNKTKEYKI 202 FP N V + +Q+ + +E PP PE E A +I+KNK++++++ Sbjct: 1101 FPANHVASETLYQELPPEIKERSPPLSPEEKTKIEKSPAPQKQSINKNKSQDFRL 1155 >gi|199559438 Abelson helper integration site 1 isoform a [Homo sapiens] Length = 1196 Score = 30.4 bits (67), Expect = 4.1 Identities = 16/55 (29%), Positives = 29/55 (52%), Gaps = 2/55 (3%) Query: 150 FPENLV--QACFQQYKTKREEVKPPSDPEMNMTEESFTAVMTTAISKNKTKEYKI 202 FP N V + +Q+ + +E PP PE E A +I+KNK++++++ Sbjct: 1101 FPANHVASETLYQELPPEIKERSPPLSPEEKTKIEKSPAPQKQSINKNKSQDFRL 1155 >gi|31542701 Abelson helper integration site 1 isoform a [Homo sapiens] Length = 1196 Score = 30.4 bits (67), Expect = 4.1 Identities = 16/55 (29%), Positives = 29/55 (52%), Gaps = 2/55 (3%) Query: 150 FPENLV--QACFQQYKTKREEVKPPSDPEMNMTEESFTAVMTTAISKNKTKEYKI 202 FP N V + +Q+ + +E PP PE E A +I+KNK++++++ Sbjct: 1101 FPANHVASETLYQELPPEIKERSPPLSPEEKTKIEKSPAPQKQSINKNKSQDFRL 1155 >gi|42476325 solute carrier family 18 (vesicular monoamine), member 2 [Homo sapiens] Length = 514 Score = 30.0 bits (66), Expect = 5.4 Identities = 18/78 (23%), Positives = 37/78 (47%) Query: 252 QIIMCYMPLGILFLIAGKIIEVEDWEIFRKLGLYMATVLTGLAIHSIVILPLIYFIVVRK 311 Q+ + ++P I +LI I + ++ R L + ++ G++I I IY ++ Sbjct: 329 QLGVAFLPASISYLIGTNIFGILAHKMGRWLCALLGMIIVGVSILCIPFAKNIYGLIAPN 388 Query: 312 NPFRFAMGMAQALLTALM 329 FA+GM + + +M Sbjct: 389 FGVGFAIGMVDSSMMPIM 406 >gi|169206294 PREDICTED: hypothetical protein [Homo sapiens] Length = 107 Score = 29.6 bits (65), Expect = 7.0 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 9/71 (12%) Query: 400 TATSASIGAAGVPQAGLVTMVIVLSA-------VGLPAEDVTLIIAVDWLLDRFRTMVNV 452 TAT +SI A PQ + + S VGL VT + DWL +R R Sbjct: 27 TATGSSISAPPKPQQPVPVSIPPASVARGSRALVGLAEASVTRQLTYDWLAERARRAPP- 85 Query: 453 LGDAFGTGIVE 463 G A G+G+ + Sbjct: 86 -GKALGSGLAD 95 >gi|113424485 PREDICTED: hypothetical protein [Homo sapiens] Length = 107 Score = 29.6 bits (65), Expect = 7.0 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 9/71 (12%) Query: 400 TATSASIGAAGVPQAGLVTMVIVLSA-------VGLPAEDVTLIIAVDWLLDRFRTMVNV 452 TAT +SI A PQ + + S VGL VT + DWL +R R Sbjct: 27 TATGSSISAPPKPQQPVPVSIPPASVARGSRALVGLAEASVTRQLTYDWLAERARRAPP- 85 Query: 453 LGDAFGTGIVE 463 G A G+G+ + Sbjct: 86 -GKALGSGLAD 95 >gi|20162572 necdin-like 2 [Homo sapiens] Length = 304 Score = 29.6 bits (65), Expect = 7.0 Identities = 11/26 (42%), Positives = 17/26 (65%) Query: 260 LGILFLIAGKIIEVEDWEIFRKLGLY 285 LG++F+ I E E W+ R+LG+Y Sbjct: 183 LGLIFMKGNTIKETEAWDFLRRLGVY 208 >gi|4759128 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 [Homo sapiens] Length = 1099 Score = 29.3 bits (64), Expect = 9.2 Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 10/63 (15%) Query: 391 IGQIITISITATSASIGAAGVPQAGLVTMVIVL----------SAVGLPAEDVTLIIAVD 440 +G+ I IS +I AAG L+T VIV S+VG D+T+ + V Sbjct: 962 VGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVP 1021 Query: 441 WLL 443 WLL Sbjct: 1022 WLL 1024 >gi|24371241 zinc finger, DHHC-type containing 14 isoform 1 [Homo sapiens] Length = 488 Score = 29.3 bits (64), Expect = 9.2 Identities = 15/71 (21%), Positives = 35/71 (49%), Gaps = 5/71 (7%) Query: 198 KEYKIVGMYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCY 257 + Y+ M+ ++ L + +F V VI + + G F NAL D+ +++ ++C+ Sbjct: 205 RNYRFFYMFILSLSFLTVFIFAFVITHVILRSQQTG-----FLNALKDSPASVLEAVVCF 259 Query: 258 MPLGILFLIAG 268 + + ++G Sbjct: 260 FSVWSIVGLSG 270 >gi|24371272 zinc finger, DHHC-type containing 14 isoform 2 [Homo sapiens] Length = 473 Score = 29.3 bits (64), Expect = 9.2 Identities = 15/71 (21%), Positives = 35/71 (49%), Gaps = 5/71 (7%) Query: 198 KEYKIVGMYSDGINVLGLIVFCLVFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCY 257 + Y+ M+ ++ L + +F V VI + + G F NAL D+ +++ ++C+ Sbjct: 205 RNYRFFYMFILSLSFLTVFIFAFVITHVILRSQQTG-----FLNALKDSPASVLEAVVCF 259 Query: 258 MPLGILFLIAG 268 + + ++G Sbjct: 260 FSVWSIVGLSG 270 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.323 0.138 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,027,309 Number of Sequences: 37866 Number of extensions: 607326 Number of successful extensions: 1688 Number of sequences better than 10.0: 24 Number of HSP's better than 10.0 without gapping: 14 Number of HSP's successfully gapped in prelim test: 10 Number of HSP's that attempted gapping in prelim test: 1650 Number of HSP's gapped (non-prelim): 24 length of query: 524 length of database: 18,247,518 effective HSP length: 107 effective length of query: 417 effective length of database: 14,195,856 effective search space: 5919671952 effective search space used: 5919671952 T: 11 A: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.