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Search of human proteins with 62548866
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62548866 integrin, alpha D precursor [Homo sapiens]
(1161 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62548866 integrin, alpha D precursor [Homo sapiens] 2310 0.0
gi|34452173 integrin alpha X precursor [Homo sapiens] 1475 0.0
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 1329 0.0
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 1325 0.0
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 540 e-153
gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ... 471 e-132
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 453 e-127
gi|148728188 integrin, alpha E precursor [Homo sapiens] 405 e-113
gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 403 e-112
gi|52485853 integrin, alpha 11 precursor [Homo sapiens] 399 e-111
gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 365 e-100
gi|116295258 integrin alpha 2 precursor [Homo sapiens] 340 5e-93
gi|67191027 integrin alpha 4 precursor [Homo sapiens] 216 1e-55
gi|52485941 integrin, alpha 9 precursor [Homo sapiens] 201 3e-51
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] 170 6e-42
gi|56237029 integrin alpha 5 precursor [Homo sapiens] 164 3e-40
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] 156 9e-38
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] 156 9e-38
gi|49170034 integrin, alpha 8 [Homo sapiens] 149 2e-35
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] 147 7e-35
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] 147 7e-35
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] 139 2e-32
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] 129 2e-29
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [... 127 6e-29
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [... 125 3e-28
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] 124 7e-28
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] 124 7e-28
gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens] 94 1e-18
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 88 5e-17
gi|11321565 matrilin 3 precursor [Homo sapiens] 85 3e-16
>gi|62548866 integrin, alpha D precursor [Homo sapiens]
Length = 1161
Score = 2310 bits (5987), Expect = 0.0
Identities = 1161/1161 (100%), Positives = 1161/1161 (100%)
Query: 1 MTFGTVLLLSVLASYHGFNLDVEEPTIFQEDAGGFGQSVVQFGGSRLVVGAPLEVVAANQ 60
MTFGTVLLLSVLASYHGFNLDVEEPTIFQEDAGGFGQSVVQFGGSRLVVGAPLEVVAANQ
Sbjct: 1 MTFGTVLLLSVLASYHGFNLDVEEPTIFQEDAGGFGQSVVQFGGSRLVVGAPLEVVAANQ 60
Query: 61 TGRLYDCAAATGMCQPIPLHIRPEAVNMSLGLTLAASTNGSRLLACGPTLHRVCGENSYS 120
TGRLYDCAAATGMCQPIPLHIRPEAVNMSLGLTLAASTNGSRLLACGPTLHRVCGENSYS
Sbjct: 61 TGRLYDCAAATGMCQPIPLHIRPEAVNMSLGLTLAASTNGSRLLACGPTLHRVCGENSYS 120
Query: 121 KGSCLLLGSRWEIIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDFNQMKGFVQAVMGQF 180
KGSCLLLGSRWEIIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDFNQMKGFVQAVMGQF
Sbjct: 121 KGSCLLLGSRWEIIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDFNQMKGFVQAVMGQF 180
Query: 181 EGTDTLFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGLTFTATGILTVVTQLFH 240
EGTDTLFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGLTFTATGILTVVTQLFH
Sbjct: 181 EGTDTLFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGLTFTATGILTVVTQLFH 240
Query: 241 HKNGARKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGVGHAFQGPTARQEL 300
HKNGARKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGVGHAFQGPTARQEL
Sbjct: 241 HKNGARKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGVGHAFQGPTARQEL 300
Query: 301 NTISSAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRASSSFQHEMSQEGFSTALT 360
NTISSAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRASSSFQHEMSQEGFSTALT
Sbjct: 301 NTISSAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRASSSFQHEMSQEGFSTALT 360
Query: 361 MDGLFLGAVGSFSWSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTELALWKGVQNLV 420
MDGLFLGAVGSFSWSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTELALWKGVQNLV
Sbjct: 361 MDGLFLGAVGSFSWSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTELALWKGVQNLV 420
Query: 421 LGAPRYQHTGKAVIFTQVSRQWRKKAEVTGTQIGSYFGASLCSVDVDSDGSTDLILIGAP 480
LGAPRYQHTGKAVIFTQVSRQWRKKAEVTGTQIGSYFGASLCSVDVDSDGSTDLILIGAP
Sbjct: 421 LGAPRYQHTGKAVIFTQVSRQWRKKAEVTGTQIGSYFGASLCSVDVDSDGSTDLILIGAP 480
Query: 481 HYYEQTRGGQVSVCPLPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAI 540
HYYEQTRGGQVSVCPLPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAI
Sbjct: 481 HYYEQTRGGQVSVCPLPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAI 540
Query: 541 GAPGEQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMD 600
GAPGEQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMD
Sbjct: 541 GAPGEQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMD 600
Query: 601 LAVGARGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQKS 660
LAVGARGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQKS
Sbjct: 601 LAVGARGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQKS 660
Query: 661 SLDQLGDIQSSVRFDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIHCETLKLLLPDCV 720
SLDQLGDIQSSVRFDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIHCETLKLLLPDCV
Sbjct: 661 SLDQLGDIQSSVRFDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIHCETLKLLLPDCV 720
Query: 721 EDVVSPIILHLNFSLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGV 780
EDVVSPIILHLNFSLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGV
Sbjct: 721 EDVVSPIILHLNFSLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGV 780
Query: 781 TLSFSGLQTLTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSA 840
TLSFSGLQTLTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSA
Sbjct: 781 TLSFSGLQTLTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSA 840
Query: 841 LRLACETVPTEDEGLRSSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASSE 900
LRLACETVPTEDEGLRSSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASSE
Sbjct: 841 LRLACETVPTEDEGLRSSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASSE 900
Query: 901 NNKASSSKATFQLELPVKYAVYTMISRQEESTKYFNFATSDEKKMKEAEHRYRVNNLSQR 960
NNKASSSKATFQLELPVKYAVYTMISRQEESTKYFNFATSDEKKMKEAEHRYRVNNLSQR
Sbjct: 901 NNKASSSKATFQLELPVKYAVYTMISRQEESTKYFNFATSDEKKMKEAEHRYRVNNLSQR 960
Query: 961 DLAISINFWVPVLLNGVAVWDVVMEAPSQSLPCVSERKPPQHSDFLTQISRSPMLDCSIA 1020
DLAISINFWVPVLLNGVAVWDVVMEAPSQSLPCVSERKPPQHSDFLTQISRSPMLDCSIA
Sbjct: 961 DLAISINFWVPVLLNGVAVWDVVMEAPSQSLPCVSERKPPQHSDFLTQISRSPMLDCSIA 1020
Query: 1021 DCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQLPGQ 1080
DCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQLPGQ
Sbjct: 1021 DCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQLPGQ 1080
Query: 1081 EAFMRAQMEMVLEEDEVYNAIPIIMGSSVGALLLLALITATLYKLGFFKRHYKEMLEDKP 1140
EAFMRAQMEMVLEEDEVYNAIPIIMGSSVGALLLLALITATLYKLGFFKRHYKEMLEDKP
Sbjct: 1081 EAFMRAQMEMVLEEDEVYNAIPIIMGSSVGALLLLALITATLYKLGFFKRHYKEMLEDKP 1140
Query: 1141 EDTATFSGDDFSCVAPNVPLS 1161
EDTATFSGDDFSCVAPNVPLS
Sbjct: 1141 EDTATFSGDDFSCVAPNVPLS 1161
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 1475 bits (3819), Expect = 0.0
Identities = 756/1151 (65%), Positives = 892/1151 (77%), Gaps = 5/1151 (0%)
Query: 2 TFGTVLLLSVLASYHGFNLDVEEPTIFQEDAGGFGQSVVQFGGSRLVVGAPLEVVAANQT 61
T +LL + LA+ GFNLD EE T F+ D+ GFG SVVQ+ S +VVGAP ++ AANQT
Sbjct: 4 TRAALLLFTALATSLGFNLDTEELTAFRVDSAGFGDSVVQYANSWVVVGAPQKITAANQT 63
Query: 62 GRLYDCAAATGMCQPIPLHIRPEAVNMSLGLTLAASTNGSRLLACGPTLHRVCGENSYSK 121
G LY C +TG C+PI L + PEAVNMSLGL+LA++T+ S+LLACGPT+H CG N Y
Sbjct: 64 GGLYQCGYSTGACEPIGLQVPPEAVNMSLGLSLASTTSPSQLLACGPTVHHECGRNMYLT 123
Query: 122 GSCLLLGSRWEIIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDFNQMKGFVQAVMGQFE 181
G C LLG ++ Q +P + ECP QE DIVFLIDGSGSI +F M FV+AV+ QF+
Sbjct: 124 GLCFLLGPT-QLTQRLPVSRQECPRQEQDIVFLIDGSGSISSRNFATMMNFVRAVISQFQ 182
Query: 182 GTDTLFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGLTFTATGILTVVTQLFHH 241
T F+LMQ+SN + HFTF +FR S + SL+ + QL+G T+TAT I VV +LFH
Sbjct: 183 RPSTQFSLMQFSNKFQTHFTFEEFRRSSNPLSLLASVHQLQGFTYTATAIQNVVHRLFHA 242
Query: 242 KNGARKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGVGHAFQGPTARQELN 301
GAR+ A KILIVITDG+K D L+Y DVIP A+ AGIIRYAIGVG AFQ + +ELN
Sbjct: 243 SYGARRDAAKILIVITDGKKEGDSLDYKDVIPMADAAGIIRYAIGVGLAFQNRNSWKELN 302
Query: 302 TISSAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRASSSFQHEMSQEGFSTALTM 361
I+S P Q+H+FKV++F AL IQ QL+EKI+A+EGT++ +SSSF+ EM+QEGFS T
Sbjct: 303 DIASKPSQEHIFKVEDFDALKDIQNQLKEKIFAIEGTETTSSSSFELEMAQEGFSAVFTP 362
Query: 362 DGLFLGAVGSFSWSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTELALWKGVQNLVL 421
DG LGAVGSF+WSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTELALWKGVQ+LVL
Sbjct: 363 DGPVLGAVGSFTWSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTELALWKGVQSLVL 422
Query: 422 GAPRYQHTGKAVIFTQVSRQWRKKAEVTGTQIGSYFGASLCSVDVDSDGSTDLILIGAPH 481
GAPRYQHTGKAVIFTQVSRQWR KAEVTGTQIGSYFGASLCSVDVDSDGSTDL+LIGAPH
Sbjct: 423 GAPRYQHTGKAVIFTQVSRQWRMKAEVTGTQIGSYFGASLCSVDVDSDGSTDLVLIGAPH 482
Query: 482 YYEQTRGGQVSVCPLPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIG 541
YYEQTRGGQVSVCPLPRG +W CDAVL GEQGHPWGRFGAALTVLGDVN DKL DV IG
Sbjct: 483 YYEQTRGGQVSVCPLPRGWRRWWCDAVLYGEQGHPWGRFGAALTVLGDVNGDKLTDVVIG 542
Query: 542 APGEQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDL 601
APGE+ENRGAVYLFHG ISPSHSQRIA SQLS RLQYFGQALSGGQDLTQDGL+DL
Sbjct: 543 APGEEENRGAVYLFHGVLGPSISPSHSQRIAGSQLSSRLQYFGQALSGGQDLTQDGLVDL 602
Query: 602 AVGARGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQKSS 661
AVGARGQVLLLR+ PVL VGV+M+F P E+ ++ + C E+ S + +CL I K S
Sbjct: 603 AVGARGQVLLLRTRPVLWVGVSMQFIPAEIPRSAFECREQVVSEQTLVQSNICLYIDKRS 662
Query: 662 LDQLG--DIQSSVRFDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIHCETLKLLLPDC 719
+ LG D+QSSV DLALDPGRL+ RA F ETKN +L+R + LGL HCE LLLP C
Sbjct: 663 KNLLGSRDLQSSVTLDLALDPGRLSPRATFQETKNRSLSRVRVLGLKAHCENFNLLLPSC 722
Query: 720 VEDVVSPIILHLNFSLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLG 779
VED V+PI L LNF+LV +P+ + +NLRP+LA +Q FTASLPFEKNCG D +C+ +LG
Sbjct: 723 VEDSVTPITLRLNFTLVGKPLLAFRNLRPMLAADAQRYFTASLPFEKNCGADHICQDNLG 782
Query: 780 VTLSFSGLQTLTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQS 839
++ SF GL++L VGS+LELN V VWN GEDSYGT ++ +PAGLS+R V+ QKQ
Sbjct: 783 ISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLR 842
Query: 840 ALRLACETVPTEDEGLRSSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASS 899
+L L C++ P +G S+ C +NH IF G+ TF+ TFDVS KA LGDR+L+ A+ SS
Sbjct: 843 SLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAVLGDRLLLTANVSS 902
Query: 900 ENNKASSSKATFQLELPVKYAVYTMISRQEESTKYFNFATSDEKKMKEAEHRYRVNNLSQ 959
ENN +SK TFQLELPVKYAVYT++S E+ TKY NF+ S+EK+ A HRY+VNNL Q
Sbjct: 903 ENNTPRTSKTTFQLELPVKYAVYTVVSSHEQFTKYLNFSESEEKESHVAMHRYQVNNLGQ 962
Query: 960 RDLAISINFWVPVLLNGVAVW-DVVMEAP-SQSLPCVSERKPPQHSDFLTQISRSPMLDC 1017
RDL +SINFWVPV LN AVW DV + P + SL C SE+ P SDFL I ++P+LDC
Sbjct: 963 RDLPVSINFWVPVELNQEAVWMDVEVSHPQNPSLRCSSEKIAPPASDFLAHIQKNPVLDC 1022
Query: 1018 SIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQL 1077
SIA CL+FRCDVPSFSVQEELDFTLKGNLSFGWVR+ LQKKV VVSVAEITFDTSVYSQL
Sbjct: 1023 SIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKVSVVSVAEITFDTSVYSQL 1082
Query: 1078 PGQEAFMRAQMEMVLEEDEVYNAIPIIMGSSVGALLLLALITATLYKLGFFKRHYKEMLE 1137
PGQEAFMRAQ VLE+ +V+N P+I+GSS+G LLLLALITA LYK+GFFKR YKEM+E
Sbjct: 1083 PGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLALITAVLYKVGFFKRQYKEMME 1142
Query: 1138 DKPEDTATFSG 1148
+ A +G
Sbjct: 1143 EANGQIAPENG 1153
>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
Length = 1152
Score = 1329 bits (3440), Expect = 0.0
Identities = 683/1140 (59%), Positives = 845/1140 (74%), Gaps = 8/1140 (0%)
Query: 6 VLLLSVLASYHGFNLDVEEPTIFQEDAGGFGQSVVQFGGSRLVVGAPLEVVAANQTGRLY 65
VLLL+ L HGFNLD E FQE+A GFGQSVVQ GSR+VVGAP E+VAANQ G LY
Sbjct: 5 VLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQRGSLY 64
Query: 66 DCAAATGMCQPIPLHIRPEAVNMSLGLTLAASTNGSRLLACGPTLHRVCGENSYSKGSCL 125
C +TG C+PI L + EAVNMSLGL+LAA+T+ +LLACGPT+H+ C EN+Y KG C
Sbjct: 65 QCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGLCF 124
Query: 126 LLGSRW-EIIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDFNQMKGFVQAVMGQFEGTD 184
L GS + Q P+A CP ++ DI FLIDGSGSI +DF +MK FV VM Q + +
Sbjct: 125 LFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSK 184
Query: 185 TLFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGLTFTATGILTVVTQLFHHKNG 244
TLF+LMQYS +IHFTF +F+ +P+ +SLV PI QL G T TATGI VV +LF+ NG
Sbjct: 185 TLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNG 244
Query: 245 ARKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGVGHAFQGPTARQELNTIS 304
ARK+A KIL+VITDG+K+ DPL Y DVIP+A++ G+IRY IGVG AF+ +RQELNTI+
Sbjct: 245 ARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIA 304
Query: 305 SAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRASSSFQHEMSQEGFSTALTMDGL 364
S PP+DHVF+V+NF AL +IQ QL+EKI+A+EGTQ+ +SSSF+HEMSQEGFS A+T +G
Sbjct: 305 SKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGP 364
Query: 365 FLGAVGSFSWSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTELALWKGVQNLVLGAP 424
L VGS+ W+GG FLY TFINM++ + DM D+YLGY+ + L VQ+LVLGAP
Sbjct: 365 LLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLVLGAP 424
Query: 425 RYQHTGKAVIFTQVSRQWRKKAEVTGTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYE 484
RYQH G +F Q + W A V GTQIG+YFGASLCSVDVDS+GSTDL+LIGAPHYYE
Sbjct: 425 RYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYE 484
Query: 485 QTRGGQVSVCPLPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAPG 544
QTRGGQVSVCPLPRGR +WQCDAVL GEQG PWGRFGAALTVLGDVN DKL DVAIGAPG
Sbjct: 485 QTRGGQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPG 544
Query: 545 EQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVG 604
E++NRGAVYLFHG S SGISPSHSQRIA S+LSPRLQYFGQ+LSGGQDLT DGL+DL VG
Sbjct: 545 EEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVG 604
Query: 605 ARGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQKSSLDQ 664
A+G VLLLRS PVL+V M F+P EVA+ V+ C ++ EAG+ VCL +QKS+ D+
Sbjct: 605 AQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDR 664
Query: 665 L--GDIQSSVRFDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIHCETLKLLLPDCVED 722
L G IQS V +DLALD GR SRA+FNETKN T + + LGL CETLKL LP+C+ED
Sbjct: 665 LREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIED 724
Query: 723 VVSPIILHLNFSLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTL 782
VSPI+L LNFSLV P+ + NLRPVLA +Q LFTA PFEKNCG D +C+ DL +T
Sbjct: 725 PVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITF 784
Query: 783 SFSGLQTLTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALR 842
SF L L VG E NV VTV N GEDSY T V+ ++P LS+R+VS Q Q Q + R
Sbjct: 785 SFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWR 844
Query: 843 LACETV-PTEDEG-LRSSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASSE 900
LACE+ TE G L+S+ CS+NHPIF E S TF +TFDV KA+LG+++L++A+ +SE
Sbjct: 845 LACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSE 904
Query: 901 NNKASSSKATFQLELPVKYAVYTMISRQEESTKYFNFATSDEKKMKEAEHRYRVNNLSQR 960
NN ++K FQLELPVKYAVY +++ STKY NF T+ E + +H+Y+V+NL QR
Sbjct: 905 NNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNF-TASENTSRVMQHQYQVSNLGQR 963
Query: 961 DLAISINFWVPVLLNGVAVWDVVMEAPSQSL--PCVSERKPPQHSDFLTQISRSPMLDCS 1018
L IS+ F VPV LN +WD S++L C ++ + P HSDFL ++ ++P+++CS
Sbjct: 964 SLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCS 1023
Query: 1019 IADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQLP 1078
IA C + +CD+P F +QEE + TLKGNLSF W +T +L+VS AEI F+ SV++ LP
Sbjct: 1024 IAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLP 1083
Query: 1079 GQEAFMRAQMEMVLEEDEVYNAIPIIMGSSVGALLLLALITATLYKLGFFKRHYKEMLED 1138
GQ AF+R+Q E +E EV N +P+I+GSSVG LLLLALITA LYKLGFFKR YK+M+ +
Sbjct: 1084 GQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDMMSE 1143
>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
Length = 1153
Score = 1325 bits (3428), Expect = 0.0
Identities = 683/1141 (59%), Positives = 845/1141 (74%), Gaps = 9/1141 (0%)
Query: 6 VLLLSVLASYHGFNLDVEEPTIFQEDAGGFGQSVVQFGGSRLVVGAPLEVVAANQTGRLY 65
VLLL+ L HGFNLD E FQE+A GFGQSVVQ GSR+VVGAP E+VAANQ G LY
Sbjct: 5 VLLLTALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQEIVAANQRGSLY 64
Query: 66 DCAAATGMCQPIPLHIRPEAVNMSLGLTLAASTNGSRLLACGPTLHRVCGENSYSKGSCL 125
C +TG C+PI L + EAVNMSLGL+LAA+T+ +LLACGPT+H+ C EN+Y KG C
Sbjct: 65 QCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGLCF 124
Query: 126 LLGSRW-EIIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDFNQMKGFVQAVMGQFEGTD 184
L GS + Q P+A CP ++ DI FLIDGSGSI +DF +MK FV VM Q + +
Sbjct: 125 LFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSK 184
Query: 185 TLFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGLTFTATGILTVVTQLFHHKNG 244
TLF+LMQYS +IHFTF +F+ +P+ +SLV PI QL G T TATGI VV +LF+ NG
Sbjct: 185 TLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNG 244
Query: 245 ARKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGVGHAFQGPTARQELNTIS 304
ARK+A KIL+VITDG+K+ DPL Y DVIP+A++ G+IRY IGVG AF+ +RQELNTI+
Sbjct: 245 ARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIA 304
Query: 305 SAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRASSSFQHEMSQEGFSTALTMDGL 364
S PP+DHVF+V+NF AL +IQ QL+EKI+A+EGTQ+ +SSSF+HEMSQEGFS A+T +G
Sbjct: 305 SKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGP 364
Query: 365 FLGAVGSFSWSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTELALWKGVQNLVLGAP 424
L VGS+ W+GG FLY TFINM++ + DM D+YLGY+ + L VQ+LVLGAP
Sbjct: 365 LLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGYAAAIILRNRVQSLVLGAP 424
Query: 425 RYQHTGKAVIFTQVSRQWRKKAEVTGTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYE 484
RYQH G +F Q + W A V GTQIG+YFGASLCSVDVDS+GSTDL+LIGAPHYYE
Sbjct: 425 RYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYE 484
Query: 485 QTRGGQVSVCPLPRG-RVQWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAP 543
QTRGGQVSVCPLPRG R +WQCDAVL GEQG PWGRFGAALTVLGDVN DKL DVAIGAP
Sbjct: 485 QTRGGQVSVCPLPRGQRARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP 544
Query: 544 GEQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAV 603
GE++NRGAVYLFHG S SGISPSHSQRIA S+LSPRLQYFGQ+LSGGQDLT DGL+DL V
Sbjct: 545 GEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTV 604
Query: 604 GARGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQKSSLD 663
GA+G VLLLRS PVL+V M F+P EVA+ V+ C ++ EAG+ VCL +QKS+ D
Sbjct: 605 GAQGHVLLLRSQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRD 664
Query: 664 QL--GDIQSSVRFDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIHCETLKLLLPDCVE 721
+L G IQS V +DLALD GR SRA+FNETKN T + + LGL CETLKL LP+C+E
Sbjct: 665 RLREGQIQSVVTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIE 724
Query: 722 DVVSPIILHLNFSLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVT 781
D VSPI+L LNFSLV P+ + NLRPVLA +Q LFTA PFEKNCG D +C+ DL +T
Sbjct: 725 DPVSPIVLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSIT 784
Query: 782 LSFSGLQTLTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSAL 841
SF L L VG E NV VTV N GEDSY T V+ ++P LS+R+VS Q Q Q +
Sbjct: 785 FSFMSLDCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSW 844
Query: 842 RLACETV-PTEDEG-LRSSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASS 899
RLACE+ TE G L+S+ CS+NHPIF E S TF +TFDV KA+LG+++L++A+ +S
Sbjct: 845 RLACESASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTS 904
Query: 900 ENNKASSSKATFQLELPVKYAVYTMISRQEESTKYFNFATSDEKKMKEAEHRYRVNNLSQ 959
ENN ++K FQLELPVKYAVY +++ STKY NF T+ E + +H+Y+V+NL Q
Sbjct: 905 ENNMPRTNKTEFQLELPVKYAVYMVVTSHGVSTKYLNF-TASENTSRVMQHQYQVSNLGQ 963
Query: 960 RDLAISINFWVPVLLNGVAVWDVVMEAPSQSL--PCVSERKPPQHSDFLTQISRSPMLDC 1017
R L IS+ F VPV LN +WD S++L C ++ + P HSDFL ++ ++P+++C
Sbjct: 964 RSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNC 1023
Query: 1018 SIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQL 1077
SIA C + +CD+P F +QEE + TLKGNLSF W +T +L+VS AEI F+ SV++ L
Sbjct: 1024 SIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLL 1083
Query: 1078 PGQEAFMRAQMEMVLEEDEVYNAIPIIMGSSVGALLLLALITATLYKLGFFKRHYKEMLE 1137
PGQ AF+R+Q E +E EV N +P+I+GSSVG LLLLALITA LYKLGFFKR YK+M+
Sbjct: 1084 PGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDMMS 1143
Query: 1138 D 1138
+
Sbjct: 1144 E 1144
>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
Length = 1170
Score = 540 bits (1392), Expect = e-153
Identities = 394/1165 (33%), Positives = 604/1165 (51%), Gaps = 77/1165 (6%)
Query: 5 TVLLLSVLASYHGF------NLDVEEPTIFQEDAGG--FGQSVVQFGGSRLVVGAPLEVV 56
TV+ +++L+ + F NLDV F G FG V+Q G ++VGAP E
Sbjct: 7 TVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNG-VIVGAPGE-- 63
Query: 57 AANQTGRLYDCAAATGMCQPIPLHIRPEAVNMSLGLTLAASTNGSRLLACGPTLHRVCGE 116
N TG LY C + TG C P+ L + LG+TLA +LAC P L R C +
Sbjct: 64 -GNSTGSLYQCQSGTGHCLPVTLR-GSNYTSKYLGMTLATDPTDGSILACDPGLSRTCDQ 121
Query: 117 NSYSKGSCLLLGSRWE--IIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDFNQMKGFVQ 174
N+Y G C L + ++Q P EC +D+VFL DGS S+ ++F ++ F++
Sbjct: 122 NTYLSGLCYLFRQNLQGPMLQGRP-GFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMK 180
Query: 175 AVMGQFEGTDTLFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGLTFTATGILTV 234
VM + T FA +Q+S K F F+ + +L+ + + LT T I V
Sbjct: 181 DVMKKLSNTSYQFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYV 240
Query: 235 VTQLFHHKNGARKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGVGHAFQGP 294
T++F + GAR A K+LI+ITDG E +D IIRY IG+G FQ
Sbjct: 241 ATEVFREELGARPDATKVLIIITDG-------EATDSGNIDAAKDIIRYIIGIGKHFQTK 293
Query: 295 TARQELNTISSAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRASSSFQHEMSQEG 354
+++ L+ +S P + V +D F L + +LQ+KIY +EGT + +SF E+S G
Sbjct: 294 ESQETLHKFASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSG 353
Query: 355 FSTALTMDGLFLGAVGSFSWSGGAF-LYPPNMSPTFINMSQENVDMRDSYLGYS-TELAL 412
S L+ +GAVG+ W+GG L TFI ++R YLGY+ T L
Sbjct: 354 ISADLSRGHAVVGAVGAKDWAGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPS 413
Query: 413 WKGVQNLVLGAPRYQHTGKAVIF--TQVSRQWRKKAEVTGTQIGSYFGASLCSVDVDSDG 470
+ L GAPRYQH G+ ++F Q W + + GTQIGSYFG LC VDVD DG
Sbjct: 414 RQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDG 473
Query: 471 STDLILIGAPHYYEQTRGGQVSVCPLPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLGDV 530
T+L+LIGAP +Y + RGG+V + R ++ ++ + L+G+ G+P GRFG A+T L D+
Sbjct: 474 ETELLLIGAPLFYGEQRGGRVFI--YQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDI 531
Query: 531 NEDKLIDVAIGAPGEQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALSGG 590
N D L+DVA+GAP E++ GAVY+F+G G+SP SQRI +Q+ +Q+FG+++ G
Sbjct: 532 NGDGLVDVAVGAPLEEQ--GAVYIFNG-RHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGV 588
Query: 591 QDLTQDGLMDLAVGARGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAG- 649
+DL DGL D+AVGA Q+++L S PV+ + M FSP E+ C + ++ G
Sbjct: 589 KDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGV 648
Query: 650 DATVCLTIQKSSLDQLGDIQSSVRFDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIHC 709
+ T+C I+ G + +++ + L LD R R +F ++ L R + + C
Sbjct: 649 NITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRH-ELRRNIAVTTSMSC 707
Query: 710 ETLKLLLPDCVEDVVSPIILHLNFSLVREPIPSPQNLR------PVLAVGSQDLFTASLP 763
P CV+D++SPI + LNFSL E +P++ R P + S T +P
Sbjct: 708 TDFSFHFPVCVQDLISPINVSLNFSLWEEE-GTPRDQRAQGKDIPPILRPSLHSETWEIP 766
Query: 764 FEKNCGQDGLCEGDLGVTLSFSGLQTLTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAG 823
FEKNCG+D CE +L V+ S + + L + + L+V +++ N ED+Y + L++P G
Sbjct: 767 FEKNCGEDKKCEANLRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPG 826
Query: 824 LSHRRVSGAQKQPHQSALRLACETVPTEDEGL-RSSRCSVNHPIFHEGSNGTFIVTFDVS 882
LS R+V +PH S + ++CE +P E L R+ C+V+ PIF G + + F+
Sbjct: 827 LSFRKVE--MLKPH-SQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTL 883
Query: 883 YKATLGDRMLMRASASSENNKA----SSSKATFQLELPVKYAVYTMISRQEESTKYFNFA 938
++ GD + + A+ + N + +S T +P+ Y + +I QE+ST Y +F
Sbjct: 884 VNSSWGDSVELHANVTCNNEDSDLLEDNSATTI---IPILYPINILIQDQEDSTLYVSF- 939
Query: 939 TSDEKKMKEAEHRYRVNNLSQRDLAISI-NFWVPVLLNGVAVWDVVMEAPSQSLPCVSER 997
T K+ + +H Y+V + SI + +P L V V E P V
Sbjct: 940 TPKGPKIHQVKHMYQVR------IQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQME 993
Query: 998 KP-PQHSDFLTQI--SRSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRET 1054
P P H + L ++ + P L ++ FRC V ++E+ + G L E
Sbjct: 994 PPVPCHYEDLERLPDAAEPCLPGAL-----FRCPV---VFRQEILVQVIGTLELVGEIEA 1045
Query: 1055 LQKKVLVVSVAEITFDTSVYSQLPGQEAFMRAQMEMVLEEDEVY--NAIPIIMGSSVGAL 1112
L S++ I+F++S + L G A + ++V++ D VY + + + S +G L
Sbjct: 1046 SSMFSLCSSLS-ISFNSSKHFHLYGSNASL---AQVVMKVDVVYEKQMLYLYVLSGIGGL 1101
Query: 1113 LLLALITATLYKLGFFKRHYKEMLE 1137
LLL LI LYK+GFFKR+ KE +E
Sbjct: 1102 LLLLLIFIVLYKVGFFKRNLKEKME 1126
>gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo
sapiens]
Length = 462
Score = 471 bits (1213), Expect = e-132
Identities = 253/452 (55%), Positives = 306/452 (67%), Gaps = 52/452 (11%)
Query: 749 VLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTLSFSGLQTLTVGSSLELNVIVTVWNAG 808
+LA +Q FTASLPFEKNCG D +C+ +LG++ SF GL++L VGS+LELN V VWN G
Sbjct: 1 MLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDG 60
Query: 809 EDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSRCSVNHPIFH 868
EDSYGT ++ +PAGLS+R V+ QKQ +L L C++ P +G S+ C +NH IF
Sbjct: 61 EDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFR 120
Query: 869 EGSNGTFIVTFDVSYKATLGDRMLMRASASSENNKASSSKATFQLELPVKYAVYTMISRQ 928
G+ TF+ TFDVS KA LGDR+L+ A+ SSENN +SK TFQLELPVKYAVYT++S
Sbjct: 121 GGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVSSH 180
Query: 929 EESTKYFNFATSDEKKMKEAEHRYR-----------VNNLSQRDLAISINFWVPVLLNGV 977
E+ TKY NF+ S+EK+ A HRY+ VNNL QRDL +SINFWVPV LN
Sbjct: 181 EQFTKYLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQE 240
Query: 978 AVW-DVVMEAP----------------------------------------SQSLPCVSE 996
AVW DV + P + SL C SE
Sbjct: 241 AVWMDVEVSHPQVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSE 300
Query: 997 RKPPQHSDFLTQISRSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQ 1056
+ P SDFL I ++P+LDCSIA CL+FRCDVPSFSVQEELDFTLKGNLSFGWVR+ LQ
Sbjct: 301 KIAPPASDFLAHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQ 360
Query: 1057 KKVLVVSVAEITFDTSVYSQLPGQEAFMRAQMEMVLEEDEVYNAIPIIMGSSVGALLLLA 1116
KKV VVSVAEITFDTSVYSQLPGQEAFMRAQ VLE+ +V+N P+I+GSS+G LLLLA
Sbjct: 361 KKVSVVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLA 420
Query: 1117 LITATLYKLGFFKRHYKEMLEDKPEDTATFSG 1148
LITA LYK+GFFKR YKEM+E+ A +G
Sbjct: 421 LITAVLYKVGFFKRQYKEMMEEANGQIAPENG 452
>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
Length = 1086
Score = 453 bits (1166), Expect = e-127
Identities = 331/973 (34%), Positives = 513/973 (52%), Gaps = 60/973 (6%)
Query: 186 LFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGLTFTATGILTVVTQLFHHKNGA 245
LFA +Q+S K F F+ + +L+ + + LT T I V T++F + GA
Sbjct: 109 LFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGA 168
Query: 246 RKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGVGHAFQGPTARQELNTISS 305
R A K+LI+ITDG+ S I A+ IIRY IG+G FQ +++ L+ +S
Sbjct: 169 RPDATKVLIIITDGEATD-----SGNIDAAKD--IIRYIIGIGKHFQTKESQETLHKFAS 221
Query: 306 APPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRASSSFQHEMSQEGFSTALTMDGLF 365
P + V +D F L + +LQ+KIY +EGT + +SF E+S G S L+
Sbjct: 222 KPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAV 281
Query: 366 LGAVGSFSWSGGAF-LYPPNMSPTFINMSQENVDMRDSYLGYS-TELALWKGVQNLVLGA 423
+GAVG+ W+GG L TFI ++R YLGY+ T L + L GA
Sbjct: 282 VGAVGAKDWAGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGA 341
Query: 424 PRYQHTGKAVIF--TQVSRQWRKKAEVTGTQIGSYFGASLCSVDVDSDGSTDLILIGAPH 481
PRYQH G+ ++F Q W + + GTQIGSYFG LC VDVD DG T+L+LIGAP
Sbjct: 342 PRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPL 401
Query: 482 YYEQTRGGQVSVCPLPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIG 541
+Y + RGG+V + R ++ ++ + L+G+ G+P GRFG A+T L D+N D L+DVA+G
Sbjct: 402 FYGEQRGGRVFI--YQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVG 459
Query: 542 APGEQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDL 601
AP E++ GAVY+F+G G+SP SQRI +Q+ +Q+FG+++ G +DL DGL D+
Sbjct: 460 APLEEQ--GAVYIFNG-RHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADV 516
Query: 602 AVGARGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAG-DATVCLTIQKS 660
AVGA Q+++L S PV+ + M FSP E+ C + ++ G + T+C I+
Sbjct: 517 AVGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSL 576
Query: 661 SLDQLGDIQSSVRFDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIHCETLKLLLPDCV 720
G + +++ + L LD R R +F ++ L R + + C P CV
Sbjct: 577 IPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRH-ELRRNIAVTTSMSCTDFSFHFPVCV 635
Query: 721 EDVVSPIILHLNFSLVREPIPSPQNLR-----PVLAVGSQDLFTASLPFEKNCGQDGLCE 775
+D++SPI + LNFSL E +P++ R P + S T +PFEKNCG+D CE
Sbjct: 636 QDLISPINVSLNFSLWEEE-GTPRDQRAGKDIPPILRPSLHSETWEIPFEKNCGEDKKCE 694
Query: 776 GDLGVTLSFSGLQTLTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQ 835
+L V+ S + + L + + L+V +++ N ED+Y + L++P GLS R+V +
Sbjct: 695 ANLRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVE--MLK 752
Query: 836 PHQSALRLACETVPTEDEGL-RSSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGDRMLMR 894
PH S + ++CE +P E L R+ C+V+ PIF G + + F+ ++ GD + +
Sbjct: 753 PH-SQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELH 811
Query: 895 ASASSENNKA----SSSKATFQLELPVKYAVYTMISRQEESTKYFNFATSDEKKMKEAEH 950
A+ + N + +S T +P+ Y + +I QE+ST Y +F T K+ + +H
Sbjct: 812 ANVTCNNEDSDLLEDNSATTI---IPILYPINILIQDQEDSTLYVSF-TPKGPKIHQVKH 867
Query: 951 RYRVNNLSQRDLAISI-NFWVPVLLNGVAVWDVVMEAPSQSLPCVSERKP-PQHSDFLTQ 1008
Y+V + SI + +P L V V E P V P P H + L +
Sbjct: 868 MYQVR------IQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLER 921
Query: 1009 I--SRSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAE 1066
+ + P L ++ FRC V ++E+ + G L E L S++
Sbjct: 922 LPDAAEPCLPGAL-----FRCPV---VFRQEILVQVIGTLELVGEIEASSMFSLCSSLS- 972
Query: 1067 ITFDTSVYSQLPGQEAFMRAQMEMVLEEDEVY--NAIPIIMGSSVGALLLLALITATLYK 1124
I+F++S + L G A + ++V++ D VY + + + S +G LLLL LI LYK
Sbjct: 973 ISFNSSKHFHLYGSNASL---AQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYK 1029
Query: 1125 LGFFKRHYKEMLE 1137
+GFFKR+ KE +E
Sbjct: 1030 VGFFKRNLKEKME 1042
Score = 51.6 bits (122), Expect = 4e-06
Identities = 41/110 (37%), Positives = 55/110 (50%), Gaps = 14/110 (12%)
Query: 5 TVLLLSVLASYHGF------NLDVEEPTIFQEDAGG--FGQSVVQFGGSRLVVGAPLEVV 56
TV+ +++L+ + F NLDV F G FG V+Q G ++VGAP E
Sbjct: 7 TVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNG-VIVGAPGE-- 63
Query: 57 AANQTGRLYDCAAATGMCQPIPLHIRPEAVNMSLGLTLAAS-TNGSRLLA 105
N TG LY C + TG C P+ L + LG+TLA T+GS L A
Sbjct: 64 -GNSTGSLYQCQSGTGHCLPVTLR-GSNYTSKYLGMTLATDPTDGSILFA 111
>gi|148728188 integrin, alpha E precursor [Homo sapiens]
Length = 1179
Score = 405 bits (1042), Expect = e-113
Identities = 299/1011 (29%), Positives = 502/1011 (49%), Gaps = 78/1011 (7%)
Query: 150 DIVFLIDGSGSIDQNDFNQMKGFVQAVMGQF--EGTDTLFALMQYSNLLKIHFTFTQFRT 207
+I ++DGSGSID DF + K F+ +M F + + FAL+QY +++ F +
Sbjct: 202 EIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQD 261
Query: 208 SPSQQSLVDPIVQLKGLTFTATGILTVVTQLFHHKNGARKSAKKILIVITDGQKYKDPLE 267
+ + V I Q+ +T TA+ + V+ +F +G+R+ A K+++V+TDG ++DPL
Sbjct: 262 VMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPLN 321
Query: 268 YSDVIPQAEKAGIIRYAIGVGHAFQGPTARQELNTISSAPPQDHVFKVDNFAALGSIQKQ 327
+ VI + G+ R+AIGVG F+ +ELN I+S P + H FKV N+ AL + +
Sbjct: 322 LTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYMALDGLLSK 381
Query: 328 LQEKIYAVEGTQSRASSSFQHEMSQEGFSTALTMDG-LFLGAVGSFSWSGGAFLYPP-NM 385
L+ I ++EGT + ++++Q GFS + + + LGAVG+F WSGGA LY +
Sbjct: 382 LRYNIISMEGT---VGDALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALLYDTRSR 438
Query: 386 SPTFINMSQENVDMRD----SYLGYSTELALWKGVQNLVLGAPRYQHTGKAVIFTQVSRQ 441
F+N + + SYLGY+ + + + GAPRY+H G + R+
Sbjct: 439 RGRFLNQTAAAAADAEAAQYSYLGYAVAVLHKTCSLSYIAGAPRYKHHGAVFELQKEGRE 498
Query: 442 WRKKAEVTGTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYEQTRGGQVSVCPLPRGRV 501
+ G Q+GSYFG+ LC VD+D DGSTD +L+ AP Y+ G+V V L
Sbjct: 499 ASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGRVYVYRLSEQDG 558
Query: 502 QWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAP------GEQENRGAVYLF 555
+ +L G G RFG A+ +GD+++DKL DVAIGAP + + G+VY++
Sbjct: 559 SFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIY 618
Query: 556 HGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVGARGQVLLLRSL 615
+G + G+S S SQRI +S ++P LQYFG +++GG D++ DGL D+ VG GQ ++ RS
Sbjct: 619 NGHWD-GLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLGQAVVFRSR 677
Query: 616 PVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAG-----DATVCLTIQK-SSLDQLGDIQ 669
PV+++ V+M F+ PSAL G + +C I ++ + G +
Sbjct: 678 PVVRLKVSMAFT---------------PSALPIGFNGVVNVRLCFEISSVTTASESGLRE 722
Query: 670 SSVRFDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIHCETLKLLLPD----CVEDVVS 725
+ + F L +D G+ R ++ ++ R+ CE L LL+P C ED S
Sbjct: 723 ALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDL-LLMPTEGELCEEDCFS 781
Query: 726 PIILHLNFSLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTLSFS 785
+ +++ L + P + +P+L ++ LP+EK C C +L + + S
Sbjct: 782 NASVKVSYQL-QTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLATTVS 840
Query: 786 GLQTLTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLAC 845
Q L VG + EL + + + N+GEDSY T ++L YP L +R+ QK P + + C
Sbjct: 841 -QQELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQLKRM---QKPPSPN---IQC 893
Query: 846 ETVPTEDEGLRSSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASSENNKAS 905
+ P + C + HP+ S +V + + A + + ++ N + S
Sbjct: 894 DD-PQPVASVLIMNCRIGHPVLKRSSAHVSVV-WQLEENAFPNRTADITVTVTNSNERRS 951
Query: 906 SSKATFQLELPVKYAVYTMISRQEESTKYFNFATSDEKKMKEAEHRYRVNNLSQRDLAIS 965
+ T L+ ++ ++S+ S Y N + + E + V+ +
Sbjct: 952 LANETHTLQF--RHGFVAVLSK--PSIMYVN---TGQGLSHHKEFLFHVHGENLFGAEYQ 1004
Query: 966 INFWVPVLLNGVAVWDVVMEAPSQ-SLPCVSERKPPQHSDFLTQISRSPMLDCSIADCLQ 1024
+ VP L G+ V V +Q S C ++ + + + C IA
Sbjct: 1005 LQICVPTKLRGLQVVAVKKLTRTQASTVCTWSQERACAYSSVQHVEEWHSVSCVIA---- 1060
Query: 1025 FRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQLPGQEAFM 1084
++ + T+ +S+ E L+ + + EI+F+ S+Y L +
Sbjct: 1061 ----------SDKENVTVAAEISWDHSEELLKDVTELQILGEISFNKSLYEGLNAEN--H 1108
Query: 1085 RAQMEMVLEEDEVYNAIPIIMGSSVGALLLLALITATLYKLGFFKRHYKEM 1135
R ++ +V +DE Y+++PII+ SVG LL+L +I L+K GFFKR Y+++
Sbjct: 1109 RTKITVVFLKDEKYHSLPIIIKGSVGGLLVLIVILVILFKCGFFKRKYQQL 1159
>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
Length = 1167
Score = 403 bits (1035), Expect = e-112
Identities = 347/1181 (29%), Positives = 560/1181 (47%), Gaps = 96/1181 (8%)
Query: 18 FNLDVEEPTIFQ-EDAGGFGQSVVQF--GGSR-LVVGAPLEVVAANQTGRLYDCAAATGM 73
FNLD P +F FG SV+Q GG R ++VGAP + + ++ G +Y C
Sbjct: 23 FNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGAPWDGPSGDRRGDVYRCPVGGAH 82
Query: 74 CQPIPL---------HIRPEAVNMSLGLTLAASTNGSRLLACGPTLHRVCGENSYSKGSC 124
P + AVNM LG++L + +AC P R CG + +S G C
Sbjct: 83 NAPCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGGFMACAPLWSRACGSSVFSSGIC 142
Query: 125 LLLGSRWEIIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDFNQMKGFVQAVMGQF--EG 182
+ + ++ ++ CP MD+V ++DGS SI +++++ F++ ++G+ +
Sbjct: 143 ARVDASFQPQGSLAPTAQRCPTY-MDVVIVLDGSNSI--YPWSEVQTFLRRLVGKLFIDP 199
Query: 183 TDTLFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGL-TFTATGILTVVTQLFHH 241
L+QY ++ FRT + + +G T TA I+ T+ F
Sbjct: 200 EQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQ 259
Query: 242 KNGARKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGV-GHAFQ---GPTA- 296
+G R A ++L+V+TDG+ + D E + E + RY I V GH + P++
Sbjct: 260 SHGGRPEAARLLVVVTDGESH-DGEELPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSF 318
Query: 297 RQELNTISSAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRASSSFQHEMSQEGFS 356
+E+ TI+S P + F V + AAL I L ++I+ +EG+ + SSF EMSQ GFS
Sbjct: 319 LREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSHAENESSFGLEMSQIGFS 378
Query: 357 TALTMDGLFLGAVGSFSW-------SGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTE 409
T DG+ G VG++ W GG L+PP M+ + + +YLGYS
Sbjct: 379 THRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMA--LEDEFPPALQNHAAYLGYSVS 436
Query: 410 LALWKGVQNLVL-GAPRYQHTGKAVIFTQVSRQW--RKKAEVTGTQIGSYFGASLCSVDV 466
L +G + L L GAPR++H GK + F Q+ + R + G QIGSYFG+ LC +D
Sbjct: 437 SMLLRGGRRLFLSGAPRFRHRGKVIAF-QLKKDGAVRVAQSLQGEQIGSYFGSELCPLDT 495
Query: 467 DSDGSTDLILIGAPHYY--EQTRGGQVSVCPLPRGRVQWQCDAVLRGE-QGHP--WGRFG 521
D DG+TD++L+ AP + + G+V V V Q L+G Q P RFG
Sbjct: 496 DRDGTTDVLLVAAPMFLGPQNKETGRVYVY-----LVGQQSLLTLQGTLQPEPPQDARFG 550
Query: 522 AALTVLGDVNEDKLIDVAIGAPGEQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQ 581
A+ L D+N+D DVA+GAP E ++GA+YL+HG ++SG+ P +QRIA++ + L
Sbjct: 551 FAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHG-TQSGVRPHPAQRIAAASMPHALS 609
Query: 582 YFGQALSGGQDLTQDGLMDLAVGARGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCWEE 641
YFG+++ G DL D L+D+AVGA+G +LL S P++ + ++ +P ++ C
Sbjct: 610 YFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAISVVQRDC--- 666
Query: 642 KPSALEAGDATVCLTIQ-----KSSLDQLGDIQSSVRFDLALDPGRLTSRAIFNETKNPT 696
G VCLT S D Q +RF +LD +RA F+ +
Sbjct: 667 ----RRRGQEAVCLTAALCFQVTSRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSGQRL 722
Query: 697 LTRRKTLGLG-IHCETLKLLLPDCVEDVVSPIILHLNFSLVREPIPSPQNLRPVLAVGSQ 755
RR L +G + CE L + D D + P+ L + F+L P PVL GS
Sbjct: 723 SPRRLRLSVGNVTCEQLHFHVLD-TSDYLRPVALTVTFALDNTTKPG-----PVLNEGSP 776
Query: 756 DLFTASLPFEKNCGQDGLCEGD--LGVTLSFSGLQT---LTVGSSLELNVIVTVWNAGED 810
+PF K+CG D C D L V + G + + G ++ V T+ N E+
Sbjct: 777 TSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLENRKEN 836
Query: 811 SYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSRCSVNHPIFHEG 870
+Y T +SL + L ++ ++ P +++ C P+ L CSV HP+F G
Sbjct: 837 AYNTSLSLIFSRNLHLASLTPQRESP----IKVEC-AAPSAHARL----CSVGHPVFQTG 887
Query: 871 SNGTFIVTFDVSYKATLGDRML-MRASASSENNKASSSKATFQLELPVKYAVYTMISRQE 929
+ TF++ F+ S + L + + AS+ S + T Q ++Y + + S +
Sbjct: 888 AKVTFLLEFEFSCSSLLSQVFVKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSES 947
Query: 930 ESTKY--FNFATSDEKKMKEAEHRYRVNNLSQRDLA-ISINFWVPVLLNGVAVWDVVMEA 986
+Y + T E + RV NL ++ + I+ +P + +G + + +
Sbjct: 948 TLHRYEVHPYGTLPVGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHGGNYFLSLSQV 1007
Query: 987 PSQSLPCVSER-----KPPQHSDFLTQISRSPMLDCSIADCLQFRCDVPSFSVQEELDFT 1041
+ + C+ + PP H + L +R L+ S C RC + + E+
Sbjct: 1008 ITNNASCIVQNLTEPPGPPVHPEELQHTNR---LNGSNTQCQVVRCHLGQLAKGTEVSVG 1064
Query: 1042 LKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQLPGQEAFMRAQMEMVLEEDEVYNAI 1101
L + + R K + VVS E+ + QL + + +E V++ + ++
Sbjct: 1065 LLRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESLLE-VVQTRPILISL 1123
Query: 1102 PIIMGSSVGALLLLALITATLYKLGFFKRHYKEMLEDKPED 1142
I++GS +G LLLLAL+ L+KLGFF H K E+K E+
Sbjct: 1124 WILIGSVLGGLLLLALLVFCLWKLGFF-AHKKIPEEEKREE 1163
>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
Length = 1188
Score = 399 bits (1025), Expect = e-111
Identities = 341/1188 (28%), Positives = 548/1188 (46%), Gaps = 116/1188 (9%)
Query: 18 FNLDVEEPTIFQEDAGGF-GQSVVQF---GGSRLVVGAPLEVVAANQTGRLYDCAAATGM 73
FN+D +P + F G +V Q G LVVGAPLE +TG +Y C G
Sbjct: 23 FNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGAPLETNGYQKTGDVYKCPVIHGN 82
Query: 74 CQPIPL------HIRPEAVNMSLGLTLAASTNGSRLLACGPTLHRVCGENSYSKGSCLLL 127
C + L ++ NM LGL+LA + + LAC P CG + Y+ G C +
Sbjct: 83 CTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFLACSPLWSHECGSSYYTTGMCSRV 142
Query: 128 GSRWEIIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDFNQMKGFVQAVMGQFE-GTDTL 186
S + +TV A C MDIV ++DGS SI + +++ F+ ++ +F G +
Sbjct: 143 NSNFRFSKTVAPALQRC-QTYMDIVIVLDGSNSI--YPWVEVQHFLINILKKFYIGPGQI 199
Query: 187 -FALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGL-TFTATGILTVVTQLFHHKNG 244
++QY + F +R+ I Q G T TA GI ++ F + G
Sbjct: 200 QVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTETRTAFGIEFARSEAF--QKG 257
Query: 245 ARKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGV-----GHAFQGPTARQE 299
RK AKK++IVITDG+ + P + VI Q+E+ + RYA+ V T E
Sbjct: 258 GRKGAKKVMIVITDGESHDSP-DLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLNE 316
Query: 300 LNTISSAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRASSSFQHEMSQEGFSTAL 359
+ I+S P H F V + AAL I L ++I+++EGT ++ +SF EMSQ GFS+ +
Sbjct: 317 IKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGT-NKNETSFGLEMSQTGFSSHV 375
Query: 360 TMDGLFLGAVGSFSWSGGAFLYPPN-----MSPTFINMSQENVDMRDSYLGYS-TELALW 413
DG+ LGAVG++ W+G + +++ E + +YLGY+ T +
Sbjct: 376 VEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKNHGAYLGYTVTSVVSS 435
Query: 414 KGVQNLVLGAPRYQHTGKAVIFTQVS-RQWRKKAEVTGTQIGSYFGASLCSVDVDSDGST 472
+ + V GAPR+ HTGK ++FT + R + G QIGSYFG+ + SVD+D DG T
Sbjct: 436 RQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGVT 495
Query: 473 DLILIGAPHYYEQTRG-GQVSVCPLPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLGDVN 531
D++L+GAP Y+ + R G+V V L + + + L+ + RFG+++ + D+N
Sbjct: 496 DVLLVGAPMYFNEGRERGKVYVYELRQNLFVY--NGTLKDSHSYQNARFGSSIASVRDLN 553
Query: 532 EDKLIDVAIGAPGEQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQ 591
+D DV +GAP E + GA+Y+FHG S I + QRI +S+L+ LQYFG ++ G
Sbjct: 554 QDSYNDVVVGAPLEDNHAGAIYIFHGFRGS-ILKTPKQRITASELATGLQYFGCSIHGQL 612
Query: 592 DLTQDGLMDLAVGARGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAGDA 651
DL +DGL+DLAVGA G ++L S PV+++ ++ F P ++ C K S +A
Sbjct: 613 DLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKINIFHRDC---KRSGRDATCL 669
Query: 652 TVCLTIQKSSL-DQLGDIQSSVRFDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIH-C 709
L L +R++ +D R T RA +E + R L G C
Sbjct: 670 AAFLCFTPIFLAPHFQTTTVGIRYNATMDERRYTPRAHLDEGGDRFTNRAVLLSSGQELC 729
Query: 710 ETLKLLLPDCVEDVVSPIILHLNFSLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCG 769
E + + D D V P+ + +SL + P+L G S+PF C
Sbjct: 730 ERINFHVLDTA-DYVKPVTFSVEYSL------EDPDHGPMLDDGWPTTLRVSVPFWNGCN 782
Query: 770 QDGLCEGDL---------------------------GVTLSFSGLQTLTVGSSLELNVIV 802
+D C DL TLSF + + + V
Sbjct: 783 EDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQRVAVEA 842
Query: 803 TVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSRCSV 862
T+ N GE++Y TV+++ A L S QK+ ++ E+ L+ C+V
Sbjct: 843 TLENRGENAYSTVLNISQSANLQF--ASLIQKEDSDGSIECV-----NEERRLQKQVCNV 895
Query: 863 NHPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASSENNKASSSKA--TFQLELPVKYA 920
++P F + F + F+ S K+ + + +A S++N+ S+K L +KY
Sbjct: 896 SYPFFRAKAKVAFRLDFEFS-KSIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHLKYE 954
Query: 921 VYTMISRQEESTKYFNFATSDEKKMKEAEHRY-----------RVNNLSQRDL-AISINF 968
+ +R + Y E K + RY R+ NL + + +
Sbjct: 955 ADVLFTRSSSLSHY-------EVKPNSSLERYDGIGPPFSCIFRIQNLGLFPIHGMMMKI 1007
Query: 969 WVPVLLNG----VAVWDVVMEAPSQSLPCVSERKPPQHSDFLTQISRSPMLDCSIADCLQ 1024
+P+ + + D + + + S + + + R+P L+ S +D +
Sbjct: 1008 TIPIATRSGNRLLKLRDFLTDEANTSCNIWGNSTEYRPTPVEEDLRRAPQLNHSNSDVVS 1067
Query: 1025 FRCDVPSFSVQEELDFTLKGNLSFGWVR--ETLQKKVLVVSVAEITFDTSVYSQLPGQEA 1082
C++ +E++F L GNL W+R + L+ K + + V +S +E
Sbjct: 1068 INCNI-RLVPNQEINFHLLGNL---WLRSLKALKYKSMKIMV-NAALQRQFHSPFIFREE 1122
Query: 1083 FMRAQMEMVLEEDEVYNA-IPIIMGSSVGALLLLALITATLYKLGFFK 1129
Q+ + + E + I II+GS++G LLLLAL+ L+KLGFF+
Sbjct: 1123 DPSRQIVFEISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFR 1170
>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
Length = 1179
Score = 365 bits (938), Expect = e-100
Identities = 329/1206 (27%), Positives = 548/1206 (45%), Gaps = 120/1206 (9%)
Query: 7 LLLSVLASYHGFNLDVEEPTIFQ---EDAGGFGQSVVQFG---GSRLVVGAPLEVVAANQ 60
LL VL FN+DV+ F ED FG +V Q+ G +++G+PL N+
Sbjct: 18 LLTVVLRCCVSFNVDVKNSMTFSGPVEDM--FGYTVQQYENEEGKWVLIGSPLVGQPKNR 75
Query: 61 TGRLYDCAAATGMCQP-----IPLHIRPEAV-----NMSLGLTLAASTNGSRLLACGPTL 110
TG +Y C G P +P++ V NM+ G TL + NG LACGP
Sbjct: 76 TGDVYKCPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPNGG-FLACGPLY 134
Query: 111 HRVCGENSYSKGSCLLLGSRWEIIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDFNQMK 170
CG Y+ G C + ++++ ++ EC Q +DIV ++DGS SI ++ +
Sbjct: 135 AYRCGHLHYTTGICSDVSPTFQVVNSIAPVQ-ECSTQ-LDIVIVLDGSNSI--YPWDSVT 190
Query: 171 GFVQAVMGQFE--GTDTLFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGL-TFT 227
F+ ++ + + T ++QY + F ++ ++ IVQ G T T
Sbjct: 191 AFLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMT 250
Query: 228 ATGILTVVTQLFHHKNGARKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGV 287
A GI T + F GAR+ KK+++++TDG+ + D VI E I R++I +
Sbjct: 251 ALGIDTARKEAFTEARGARRGVKKVMVIVTDGESH-DNHRLKKVIQDCEDENIQRFSIAI 309
Query: 288 -GHAFQGPTARQ----ELNTISSAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRA 342
G +G + + E+ +I+S P + H F V + AL +I K L E+I+A+E T ++
Sbjct: 310 LGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQS 369
Query: 343 SSSFQHEMSQEGFSTALTMDGLFLGAVGSFSWSGGAFLYPPNM-----SPTFINMSQENV 397
++SF+ EMSQ GFS + D + LGAVG++ W+G + + + TF S +
Sbjct: 370 AASFEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKN 429
Query: 398 DMRDSYLGYSTELALWKGVQNL-VLGAPRYQHTGKAVIFTQVSRQWRKKAEVTGTQIGSY 456
+ SYLGY+ A L + G PRY HTG+ +I+ + ++G QIGSY
Sbjct: 430 EPLASYLGYTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSY 489
Query: 457 FGASLCSVDVDSDGSTDLILIGAPHYY--EQTRGGQVSVCPLPRGRVQWQC--------- 505
FG+ L + D+D D +TD++L+GAP Y E+ G+V V L + R ++Q
Sbjct: 490 FGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTC 549
Query: 506 ------DAVLRGEQGHPWG-RFGAALTVLGDVNEDKLIDVAIGAPGEQENRGAVYLFHGA 558
++ + P G RFG A+ + D+N D D+ IGAP E ++ GAVY++HG+
Sbjct: 550 CSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGS 609
Query: 559 SESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVGARGQVLLLRSLPVL 618
++ I ++QRI S L++FGQ++ G DL DGL D+ +G G L S V
Sbjct: 610 GKT-IRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVA 668
Query: 619 KVGVAMRFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQ-KSSLDQLGDIQSSVRFDLA 677
V V M F P +V C E + +ATVC ++ KS D + ++ +++ +
Sbjct: 669 VVKVTMNFEPNKVNIQKKNCHMEGKETV-CINATVCFDVKLKSKEDTI--YEADLQYRVT 725
Query: 678 LDPGRLTSRAIFNETKNPTLTRRKTLGLGIHCETLKLLLPDCVEDVVSPIILHLNFSLVR 737
LD R SR+ F+ T+ + R T+ C + D D + + L+F+L
Sbjct: 726 LDSLRQISRSFFSGTQERKVQRNITVRKS-ECTKHSFYMLD-KHDFQDSVRITLDFNLT- 782
Query: 738 EPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTLSFSGLQTLTVGSSLE 797
P+N PVL + +PF K+CG C DL + ++ + L V S +
Sbjct: 783 ----DPEN-GPVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQND 837
Query: 798 -LNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLR 856
NV +TV N + +Y T ++Y L + QK +CE+
Sbjct: 838 KFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD--------SCES-------NH 882
Query: 857 SSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGD-RMLMRASASSENNKASSSKATFQLEL 915
+ C V +P G TF + F + + + + + A++ SE + S + +
Sbjct: 883 NITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISI 942
Query: 916 PVKYAV-----------YTMISRQEESTKYFNFATSDEKKMKEAEHRYRVNNLSQRDLAI 964
PVKY V + I+ E + N ++ + + +L +
Sbjct: 943 PVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKL 1002
Query: 965 SINFWVPVLLNGVAVWDVVMEAPSQSLPC--------VSERKPPQHSDFLTQISRSPMLD 1016
SI+F + NG V + S++ C S + + + R +LD
Sbjct: 1003 SISF-PNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILD 1061
Query: 1017 CSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQ 1076
C+ C++ S + + N+S + T K S +T + S+
Sbjct: 1062 CNTCKFATITCNLTSSDISQV-------NVSLILWKPTFIKSYF--SSLNLTIRGELRSE 1112
Query: 1077 ---LPGQEAFMRAQMEMVLEEDEVYNAIP--IIMGSSVGALLLLALITATLYKLGFFKRH 1131
L + + ++ + + +D + +P +I+ S+ LLLL L+ L+K+GFFKR
Sbjct: 1113 NASLVLSSSNQKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFKRP 1172
Query: 1132 YKEMLE 1137
K+ +E
Sbjct: 1173 LKKKME 1178
>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
Length = 1181
Score = 340 bits (872), Expect = 5e-93
Identities = 321/1214 (26%), Positives = 537/1214 (44%), Gaps = 134/1214 (11%)
Query: 8 LLSVLASYHG-------FNLDVEEPTIFQEDAGG-FGQSVVQF---GGSRLVVGAPLEVV 56
LL VLA G +N+ + E IF + FG +V QF G+ L+VG+P
Sbjct: 13 LLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGF 72
Query: 57 AANQTGRLYDCAA--ATGMCQPIPL-------HIRPEAVNMSLGLTLAASTNGSRLLACG 107
N+ G +Y C +T C+ + L ++ NMSLGL L + L CG
Sbjct: 73 PENRMGDVYKCPVDLSTATCEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFLTCG 132
Query: 108 PTLHRVCGENSYSKGSCLLLGSRWEIIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDF- 166
P + CG Y+ G C + +++ + AT CP +D+V + D S SI D
Sbjct: 133 PLWAQQCGNQYYTTGVCSDISPDFQLSASFSPATQPCPSL-IDVVVVCDESNSIYPWDAV 191
Query: 167 -NQMKGFVQAVMGQFEGTDTLFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKG-L 224
N ++ FVQ + T T L+QY+N ++ F ++T Q G L
Sbjct: 192 KNFLEKFVQGL--DIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDL 249
Query: 225 TFTATGILTVVTQLFHHKNGARKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYA 284
T T I + +G R+SA K+++V+TDG+ + D VI Q I+R+
Sbjct: 250 TNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESH-DGSMLKAVIDQCNHDNILRFG 308
Query: 285 IGV-----GHAFQGPTARQELNTISSAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQ 339
I V +A +E+ I+S P + + F V + AAL L E+I+++EGT
Sbjct: 309 IAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGTV 368
Query: 340 SRASSSFQHEMSQEGFSTALTM--DGLFLGAVGSFSWSG--------GAFLYPPNMSPTF 389
+ +FQ EMSQ GFS + D L LGAVG+F WSG G ++P F
Sbjct: 369 -QGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQ---AF 424
Query: 390 INMSQENVDMRDSYLGYSTELALWKGVQNLVLGAPRYQHTGKAVIFTQVSRQWRKKAEVT 449
+ Q+ SYLGYS + V GAPR +TG+ V+++ + +T
Sbjct: 425 DQILQDR--NHSSYLGYSVAAISTGESTHFVAGAPRANYTGQIVLYSV-----NENGNIT 477
Query: 450 ------GTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYEQTR--GGQVSVCPLPRGRV 501
G QIGSYFG+ LCSVDVD D TD++L+GAP Y + G+V + + G +
Sbjct: 478 VIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGIL 537
Query: 502 QWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAPGEQENRGAVYLFHGASES 561
L G +G RFG+A+ L D+N D DV +G+P E +N GAVY+++G +
Sbjct: 538 GQH--QFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNG-HQG 594
Query: 562 GISPSHSQRIASSQ--LSPRLQYFGQALSGGQDLTQDGLMDLAVGARGQVLLLRSLPVLK 619
I +SQ+I S LQYFG++L G DL D + D+++GA GQV+ L S +
Sbjct: 595 TIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIAD 654
Query: 620 VGVAMRFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQKSS--LDQLGDIQSSVRFDLA 677
V + F+P ++ L +A + L + S+ + Q ++ +++
Sbjct: 655 VAIEASFTPEKI-------------TLVNKNAQIILKLCFSAKFRPTKQNNQVAIVYNIT 701
Query: 678 LD----PGRLTSRAIFNETKNPTLTRRKTLGLGIHCETLKLLLPDCVEDVVSPIILHLNF 733
LD R+TSR +F E L + + C + + + DVV+ + L ++
Sbjct: 702 LDADGFSSRVTSRGLFKENNERCLQKNMVVNQAQSCPEHIIYIQE-PSDVVNSLDLRVDI 760
Query: 734 SLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTL----SFSGLQT 789
SL P L S+ S+PF K+CG+DGLC DL + + +
Sbjct: 761 SL------ENPGTSPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPF 814
Query: 790 LTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVP 849
+ + L VT+ N E +Y T + + + L A + C+
Sbjct: 815 IVSNQNKRLTFSVTLKNKRESAYNTGIVVDFSENLFF-----ASFSLPVDGTEVTCQVAA 869
Query: 850 TEDEGLRSSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASSENNKASSSKA 909
++ +S C V +P TF + FD + + L ++ + A SE+ + + +
Sbjct: 870 SQ----KSVACDVGYPALKREQQVTFTINFDFNLQ-NLQNQASLSFQALSESQEENKADN 924
Query: 910 TFQLELPVKYAVYTMISRQEESTKYFNFATSDEKKMKEAEHRYR------VNNLSQRDLA 963
L++P+ Y ++R ST + S + + H + + +L +
Sbjct: 925 LVNLKIPLLYDAEIHLTR---STNINFYEISSDGNVPSIVHSFEDVGPKFIFSLKVTTGS 981
Query: 964 ISINFWVPVL--------LNGVAVWDVVMEAPSQSLPCVSERKPPQHSDFLTQIS----- 1010
+ ++ ++ N + V + + C ++ P + + +S
Sbjct: 982 VPVSMATVIIHIPQYTKEKNPLMYLTGVQTDKAGDISCNADINPLKIGQTSSSVSFKSEN 1041
Query: 1011 --RSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEI- 1067
+ L+C A C C + ++ E + + G + + V + + AEI
Sbjct: 1042 FRHTKELNCRTASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFASSTFQTVQLTAAAEIN 1101
Query: 1068 TFDTSVYSQLPGQEAFMRAQMEMVLEEDEVYNAIPIIMGSSVGALLLLALITATLYKLGF 1127
T++ +Y ++ + + ++ +++ +I+GS + +LLL + A L+KLGF
Sbjct: 1102 TYNPEIYVI---EDNTVTIPLMIMKPDEKAEVPTGVIIGSIIAGILLLLALVAILWKLGF 1158
Query: 1128 FKRHYKEMLEDKPE 1141
FKR Y++M ++ E
Sbjct: 1159 FKRKYEKMTKNPDE 1172
>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
Length = 1032
Score = 216 bits (549), Expect = 1e-55
Identities = 228/840 (27%), Positives = 387/840 (46%), Gaps = 74/840 (8%)
Query: 352 QEGFSTALTMDGLFLGAVGSFSWSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTELA 411
Q G S+ T D + +GA GS W+G F+Y + + ++N SYLGYS
Sbjct: 199 QAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYKAFLDKQNQVKFGSYLGYSVGAG 258
Query: 412 LWKG--VQNLVLGAPRYQHTGKAVIFTQVSRQWRKKAEVTGTQIGSYFGASLCSVDVDSD 469
++ +V GAP+++ GKA IF+ ++ E+ G ++GSYFGAS+C+VD+++D
Sbjct: 259 HFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEMKGKKLGSYFGASVCAVDLNAD 318
Query: 470 GSTDLILIGAPHYYEQTRGGQVSV-CPLPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLG 528
G +DL L+GAP G+V V G V + L G + RFG ++ LG
Sbjct: 319 GFSDL-LVGAPMQSTIREEGRVFVYINSGSGAVMNAMETNLVGSDKYA-ARFGESIVNLG 376
Query: 529 DVNEDKLIDVAIGAPGEQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALS 588
D++ D DVAIGAP E + +GA+Y+++G ++ GIS + SQRI Q+S L FGQ++S
Sbjct: 377 DIDNDGFEDVAIGAPQEDDLQGAIYIYNGRAD-GISSTFSQRIEGLQISKSLSMFGQSIS 435
Query: 589 GGQDLTQDGLMDLAVGA--RGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEK-PSA 645
G D +G +D+AVGA +LLR+ PV+ V ++ P V + + C E PS
Sbjct: 436 GQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLS-HPESVNRTKFDCVENGWPSV 494
Query: 646 LEAGDATVCLTIQKSSLDQLGDIQSSVRFDLALDPGRLTS---RAIF--NETKNPTLTRR 700
D T+C + + + G I + ++++LD R R F N T +
Sbjct: 495 --CIDLTLCFSYKGKEVP--GYI--VLFYNMSLDVNRKAESPPRFYFSSNGTSDVITGSI 548
Query: 701 KTLGLGIHCETLKLLLPDCVEDVVSPIILHLNFSLVREPIPSPQN-----LRPVLAVGSQ 755
+ +C T + + V D+++PI + + L I L+P+L +
Sbjct: 549 QVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPILQQKKE 608
Query: 756 -DLFTASLPFEKNCGQDGLCEGDLGVTLSFSGLQT------LTVGSSLELNVIVTVWNAG 808
D+ ++ F + C + C DL V+ L+ L VGS L + V+++NAG
Sbjct: 609 KDIMKKTINFARFCAHEN-CSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAG 667
Query: 809 EDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSRCSVNHPIFH 868
+D+Y T + + P GL ++ +++ ++ CE T++ G+ CS+ +
Sbjct: 668 DDAYETTLHVKLPVGLYFIKILELEEK------QINCEV--TDNSGVVQLDCSIGYIYVD 719
Query: 869 EGSNGTFIVTFDVSYKATLGDRMLMRASASSENNKASSS--KATFQLELPVKYAVYTMIS 926
S DVS + + + + A+ EN + + + + +P+KY V +
Sbjct: 720 HLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVH 779
Query: 927 RQEESTKYFNFATSDE--------KKMKEAEHRYRVNNLSQRDLAISI---NFWVP---V 972
T F + ++DE +KM H N ++++ I N + P
Sbjct: 780 GFVNPTS-FVYGSNDENEPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQTDK 838
Query: 973 LLNGVAVWDVVMEAPSQSLP--CVSERKPPQHSD------FLTQISRSPMLDCSIAD--C 1022
L N + V E ++ C E++ FL++ + +L C AD C
Sbjct: 839 LFNILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKR-LLYCIKADPHC 897
Query: 1023 LQFRCDVPSFSVQEE--LDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQLPGQ 1080
L F C+ +E + L+G S + ET K + + + V +L
Sbjct: 898 LNFLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVI-ELNKD 956
Query: 1081 EAFMRAQME-MVLEEDEVYNAIPIIMGSSVGALLLLALITATLYKLGFFKRHYKEMLEDK 1139
E +E + + + Y I II S + L++L LI+ ++K GFFKR YK +L+++
Sbjct: 957 ENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEE 1016
Score = 30.8 bits (68), Expect = 7.8
Identities = 38/144 (26%), Positives = 58/144 (40%), Gaps = 14/144 (9%)
Query: 462 CSVDVDSDGSTDLILIGAPHYYEQTRGGQVSVCPLPRGRVQWQCDAVLRGEQGHPWGRFG 521
C + S + DLI++GAP T G + V + + + A L + +G +
Sbjct: 198 CQAGISSFYTKDLIVMGAPGSSYWT--GSLFVYNITTNKYK----AFLDKQNQVKFGSYL 251
Query: 522 AALTVLGDVNEDKLIDVAIGAPGEQENRGAVYLFHGASESGISPSHSQRIASSQLSPRLQ 581
G +V GAP + E G Y+F E ++ H + +L
Sbjct: 252 GYSVGAGHFRSQHTTEVVGGAP-QHEQIGKAYIF-SIDEKELNILHEMK--GKKLG---S 304
Query: 582 YFGQALSGGQDLTQDGLMDLAVGA 605
YFG ++ DL DG DL VGA
Sbjct: 305 YFGASVC-AVDLNADGFSDLLVGA 327
>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
Length = 1035
Score = 201 bits (511), Expect = 3e-51
Identities = 223/852 (26%), Positives = 383/852 (44%), Gaps = 86/852 (10%)
Query: 347 QHEMSQEGFSTALTMDGLFLGAVGSFSWSGGAFLYPPNMSP-TFINMSQENV-DMRDSYL 404
+H Q G + T + + +GA GSF W+G + N++ T++ ++ E + + R +YL
Sbjct: 190 EHGSCQAGIAGFFTEELVVMGAPGSFYWAGTIKVL--NLTDNTYLKLNDEVIMNRRYTYL 247
Query: 405 GYSTELALWK--GVQNLVLGAPRYQHTGKAVIFTQVSRQWR--KKAEVTGTQIGSYFGAS 460
GY+ + ++V GAP+ + GK IF R K + +G ++GSYFG+S
Sbjct: 248 GYAVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSS 307
Query: 461 LCSVDVDSDGSTDLILIGAPHYYEQTRGGQVSVCPLPRGRVQWQCDAVLRGEQGHPWGRF 520
LC+VD++ DG +DL L+GAP + E GQV+V + RG + L G+ + F
Sbjct: 308 LCAVDLNGDGLSDL-LVGAPMFSEIRDEGQVTVY-INRGNGALEEQLALTGDGAYN-AHF 364
Query: 521 GAALTVLGDVNEDKLIDVAIGAPGEQENRGAVYLFHGASESGISPSHSQRIASSQLSPRL 580
G ++ L D++ D DVAIGAP E + GAVY++HG + GI P +S +++ +++P L
Sbjct: 365 GESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDA-GGIVPQYSMKLSGQKINPVL 423
Query: 581 QYFGQALSGGQDLTQDGLMDLAVGA--RGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRC 638
+ FGQ++SGG D+ +G D+ VGA V+LLR+ PV+ V V++ F P + +C
Sbjct: 424 RMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDVSI-FLPGSINITAPQC 482
Query: 639 WEEKPSALEAGDATVCLTIQKSSLDQLGDIQSSVRFDLALDPGRLTSRAIF---NETKNP 695
+ + + T C + + + + D+A R F ET
Sbjct: 483 -HDGQQPVNCLNVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYFVLLGETMGQ 541
Query: 696 TLTRRKTLGLGIHCETLKLLLPDCVEDVVSPIILHLNFSLVREPIPSPQN----LRPVL- 750
+ + + C + V+DV+SPI+ +SL + L PVL
Sbjct: 542 VTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPPLTPVLR 601
Query: 751 -AVGSQDLFTASLPFEKNCGQDGLCEGDLGV--TLSFSGLQT----LTVGSSLELNVIVT 803
G + FE+NC + C DL + L S + L +G+ +++ ++
Sbjct: 602 WKKGQKIAQKNQTVFERNCRSED-CAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNIS 660
Query: 804 VWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSRCSVN 863
+ N G+D+Y VS L ++ QK+ + ++CE + ++ +CSV
Sbjct: 661 ISNLGDDAYDANVSFNVSRELFF--INMWQKE----EMGISCELLESD-----FLKCSVG 709
Query: 864 HPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASSENNKASSS--KATFQLELPVKYAV 921
P S F V FD S+ + + + +A S N + S S T L +P+ + V
Sbjct: 710 FPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEV 769
Query: 922 YTMISR--------QEESTKYFNFATSD--EKKMKEAEHRYRVNNLSQRDL---AISINF 968
T I+ ES NF D E + +V N L ++SI+F
Sbjct: 770 DTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQPINITLQVYNTGPSTLPGSSVSISF 829
Query: 969 WVPVLLNGVAVWDV-VMEAPSQSLPCVSERKP-----PQHSD--------FLTQISRSPM 1014
+ G ++ V M + C ++ P PQ + F T+ R +
Sbjct: 830 PNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFHTIFAFFTKSGRK-V 888
Query: 1015 LDCSI--ADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTS 1072
LDC CL C+ + + +E + L+ +++ + +S A++ D +
Sbjct: 889 LDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPA 948
Query: 1073 VYSQLPGQEAFMRAQMEMVLEEDEVYNAIP-------IIMGSSVGALLLLALITATLYKL 1125
L E E+ + + ++N P II S + +L+ L+ L+K+
Sbjct: 949 ----LRVVEIAHGNPEEVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKM 1004
Query: 1126 GFFKRHYKEMLE 1137
GFF+R YKE++E
Sbjct: 1005 GFFRRRYKEIIE 1016
>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
Length = 1039
Score = 170 bits (431), Expect = 6e-42
Identities = 221/880 (25%), Positives = 366/880 (41%), Gaps = 117/880 (13%)
Query: 345 SFQHEMSQEGFSTALTMDG-LFLGAVGSFSWSG----------------GAFLYPPNMSP 387
S+ + GFS+ +T G L LGA G + + G G L+ ++S
Sbjct: 192 SWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLW--HVSS 249
Query: 388 TFINMSQENVDMRDSYLGYSTELALWKGVQNL---VLGAPRYQHTGKAVIFTQVSRQWRK 444
++ N + D Y GYS + + G N V+GAP + T AV + +++
Sbjct: 250 QSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEI--LDSYYQR 307
Query: 445 KAEVTGTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYEQTRG------GQVSVCPLPR 498
+ G Q+ SYFG S+ DV+ DG DL L+GAP Y E G+V + PR
Sbjct: 308 LHRLRGEQMASYFGHSVAVTDVNGDGRHDL-LVGAPLYMESRADRKLAEVGRVYLFLQPR 366
Query: 499 G-RVQWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAP-GEQENRGAVYLFH 556
G +L G Q +GRFG+A+ LGD++ D D+A+ AP G RG V +F
Sbjct: 367 GPHALGAPSLLLTGTQ--LYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFL 424
Query: 557 GASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVGARG--QVLLLRS 614
G SE G+ SQ + S P FG +L G D+ +G DL VGA G QV + R+
Sbjct: 425 GQSE-GLRSRPSQVLDSP--FPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRA 481
Query: 615 LPVLKVGVAMRFSPVEVAKAVYRC-WEEKPSALEAGDATVCLTIQKSSLDQLGDIQSSVR 673
PV+K V + + AV C + + + + +C+ ++ Q + + ++
Sbjct: 482 QPVVKASVQLLVQD-SLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQ 540
Query: 674 FDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIH---CETLKLLLPDCVE--DVVSPII 728
D R R + ++ T LG G H C T L D + D +SPI+
Sbjct: 541 LD--RQKPRQGRRVLLLGSQQAGTTLNLDLG-GKHSPICHTTMAFLRDEADFRDKLSPIV 597
Query: 729 LHLNFSLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTLSFSGLQ 788
L LN SL P+ + P + + +CG+D +C L +T S +G
Sbjct: 598 LSLNVSLP----PTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTG-S 652
Query: 789 TLTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETV 848
L VG+ L + + N GE +Y ++++ P G + R + RL C
Sbjct: 653 PLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNV----EGFERLICN-- 706
Query: 849 PTEDEGLRSSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASSENNKASSSK 908
++ R C + +P+ G ++ V G+ + + S+N++ +SK
Sbjct: 707 QKKENETRVVLCELGNPMKKNAQIGIAMLV-SVGNLEEAGESVSFQLQIRSKNSQNPNSK 765
Query: 909 ATFQLELPVKYAVYTMISRQEESTKYFNFATSDEKKMK-------EAEHRYRVNNL---S 958
L++PV+ + A E++ + EH Y ++N +
Sbjct: 766 IVL-LDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGT 824
Query: 959 QRDLAISIN------------------------FWVPVLLNGVAVWDVVMEAPSQSLPCV 994
L +SI+ F P + W + + +PS P
Sbjct: 825 VNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAH 884
Query: 995 SERKPPQ----HSDFLTQISRSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGW 1050
+R Q + +++ ++ C A C +CD+ + + T+ L+F W
Sbjct: 885 HKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTV---LAFLW 941
Query: 1051 VRETLQK---KVLVVSVAEITFDTSVYS----QLPGQEAFMRAQMEMVLEEDEVYNAIPI 1103
+ Q+ + ++ S A + Y+ LP EA + Q+ LEE AIPI
Sbjct: 942 LPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEE----RAIPI 997
Query: 1104 --IMGSSVGALLLLALITATLYKLGFFKRHYKEMLEDKPE 1141
++ +G LLLL ++ ++K+GFFKR+ + ED E
Sbjct: 998 WWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEE 1037
>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
Length = 1049
Score = 164 bits (416), Expect = 3e-40
Identities = 223/856 (26%), Positives = 356/856 (41%), Gaps = 110/856 (12%)
Query: 352 QEGFSTALTMDG-LFLGAVGSFSWSGGAF----------LYPPNMSPTFINMSQENVDMR 400
Q GFS T G + LG GS+ W G YP + IN+ Q + R
Sbjct: 206 QGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIAESYYPEYL----INLVQGQLQTR 261
Query: 401 -------DSYLGYSTELALWKG--VQNLVLGAPRYQHTGKAVIFTQVSRQWRKKAEVTGT 451
DSYLGYS + + G ++ V G P+ T V S R +G
Sbjct: 262 QASSIYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVTILNGS-DIRSLYNFSGE 320
Query: 452 QIGSYFGASLCSVDVDSDGSTDLILIGAPHYYEQTRGGQVSVCPLPRGRVQWQCDAVLRG 511
Q+ SYFG ++ + DV+ DG DL L+GAP ++T G+ P GRV
Sbjct: 321 QMASYFGYAVAATDVNGDGLDDL-LVGAPLLMDRTPDGR----PQEVGRVYVYLQHPAGI 375
Query: 512 EQ-------GHP-WGRFGAALTVLGDVNEDKLIDVAIGAP-GEQENRGAVYLFHGASES- 561
E GH +GRFG++LT LGD+++D DVAIGAP G + +G V++F G
Sbjct: 376 EPTPTLTLTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPGGPGGL 435
Query: 562 GISPSH-SQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVGARG--QVLLLRSLPVL 618
G PS Q + ++ +P +FG AL GG+DL +G DL VG+ G + ++ R P++
Sbjct: 436 GSKPSQVLQPLWAASHTP--DFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPIV 493
Query: 619 KVGVAMRFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQKSSLDQLGDIQSSVRF--DL 676
++ P EE+ +LE G+ C+ + + S+ F +L
Sbjct: 494 SASASLTIFPAMFNP------EERSCSLE-GNPVACINLSFCLNASGKHVADSIGFTVEL 546
Query: 677 ALDPGRL---TSRAIFNETKNPTLTRRKTLGLGIH--CETLKLLLPDCVE--DVVSPIIL 729
LD + RA+F ++ TLT+ + G C +K+ L + E D +SPI +
Sbjct: 547 QLDWQKQKGGVRRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHI 606
Query: 730 HLNFSLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTLSFSGLQT 789
LNFSL + LRP L S+ +CG+D +C DL + + F
Sbjct: 607 ALNFSLDPQAPVDSHGLRPALHYQSKSRIEDKAQILLDCGEDNICVPDLQLEV-FGEQNH 665
Query: 790 LTVGSSLELNVIVTVWNAGE-DSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETV 848
+ +G LN+ N GE +Y + + P + SG + P + L+C+
Sbjct: 666 VYLGDKNALNLTFHAQNVGEGGAYEAELRVTAPPEAEY---SGLVRHPGNFS-SLSCDYF 721
Query: 849 PTEDEGLRSSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASSEN-NKASSS 907
R C + +P+ G++ + F V + + S+N N + S
Sbjct: 722 AVNQS--RLLVCDLGNPM-KAGASLWGGLRFTVPHLRDTKKTIQFDFQILSKNLNNSQSD 778
Query: 908 KATFQLELPVKYAVYTMISRQEESTKY--FNFATSDEKKMKE-----AEHRYRVNNLSQR 960
+F+L + + V + E+ + ++ D+ + +E H Y + N
Sbjct: 779 VVSFRLSVEAQAQVTLNGVSKPEAVLFPVSDWHPRDQPQKEEDLGPAVHHVYELINQGPS 838
Query: 961 DLAISI-NFWVPVLLNGVAVWDVVMEA------------------PSQSLPCVSERKPPQ 1001
++ + P L G + V P SL +R+ P
Sbjct: 839 SISQGVLELSCPQALEGQQLLYVTRVTGLNCTTNHPINPKGLELDPEGSLHHQQKREAPS 898
Query: 1002 HSDFLTQISRSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLV 1061
S + S +L C A+C + RC++ QE L + W + LQ++
Sbjct: 899 RS---SASSGPQILKCPEAECFRLRCELGPLHQQESQSLQLHFRV---WAKTFLQREHQP 952
Query: 1062 VSV-AEITFDT------SVYSQLPGQEAFMRAQMEMVLEEDEVYNAIPIIMGSSVGALLL 1114
S+ E + + QLP +E + ++ E + II+ + + LLL
Sbjct: 953 FSLQCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLWIIILAILFGLLL 1012
Query: 1115 LALITATLYKLGFFKR 1130
L L+ LYKLGFFKR
Sbjct: 1013 LGLLIYILYKLGFFKR 1028
Score = 33.1 bits (74), Expect = 1.6
Identities = 37/131 (28%), Positives = 49/131 (37%), Gaps = 30/131 (22%)
Query: 6 VLLLSVLASYHGFNLDVEEPTIFQEDAGGFGQSVVQF-----GGSRLVVGAP---LEVVA 57
+LLL GFNLD E P + G F V+F G ++VGAP
Sbjct: 30 LLLLPPPPRVGGFNLDAEAPAVLSGPPGSFFGFSVEFYRPGTDGVSVLVGAPKANTSQPG 89
Query: 58 ANQTGRLYDC--AAATGMCQPIPLHIRPEAVNMS------------------LGLTLAAS 97
Q G +Y C A+ C PI + + S G T+ A
Sbjct: 90 VLQGGAVYLCPWGASPTQCTPIEFDSKGSRLLESSLSSSEGEEPVEYKSLQWFGATVRA- 148
Query: 98 TNGSRLLACGP 108
+GS +LAC P
Sbjct: 149 -HGSSILACAP 158
>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
Length = 1051
Score = 156 bits (395), Expect = 9e-38
Identities = 139/516 (26%), Positives = 244/516 (47%), Gaps = 69/516 (13%)
Query: 350 MSQEGFSTALTMDGLFLGAVGSFSWSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTE 409
M Q G S T + ++ GA G+++W G +++ ++ D + Y+GY+ +
Sbjct: 196 MCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQGNLYIGYTMQ 255
Query: 410 LALW----KGVQNLVLGAPRYQHTGKAVIFTQ-VSRQWRKKAEVTGTQIGSYFGASLCSV 464
+ + K + +V GAPR++H G + +Q R++ + G+Q+G+YFG+++
Sbjct: 256 VGSFILHPKNI-TIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIALA 314
Query: 465 DVDSDGSTDLILIGAPHYYEQTR--GGQVSVCPLPRG-RVQWQCDAVLRGEQGHPWGRFG 521
D+++DG DL L+GAP+Y+E+ GG + V G +L G G FG
Sbjct: 315 DLNNDGWQDL-LVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSG---SAFG 370
Query: 522 AALTVLGDVNEDKLIDVAIGAPGEQENRGAVYLFHGASESGISPSHSQRIASSQLS-PRL 580
++ +GD+N+D D+A+GAP E G VY++H +S+ G+ Q I +L P L
Sbjct: 371 LSVASIGDINQDGFQDIAVGAP--FEGLGKVYIYHSSSK-GLLRQPQQVIHGEKLGLPGL 427
Query: 581 QYFGQALSGGQDLTQDGLMDLAVGA-RGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCW 639
FG +LSG D+ ++ DL VG+ ++LLR+ PV+ + V++
Sbjct: 428 ATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINI--------------VHKTL 473
Query: 640 EEKPSALEAGDAT--------VCLTIQKSSLDQLGDIQSSVRFDLALDPGRLTSRAIFNE 691
+P+ L+ T +C +S+ + ++ + L D R R F
Sbjct: 474 VPRPAVLDPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAG 533
Query: 692 TKNPTLTRRKTLGLGIHCETLKLLLPDCVEDVVSPIILHLNFSLVREPIPSPQNLRPVLA 751
+++ ++ + C+ L+LLL D + D + PII+ +N+SL P+ P RP L
Sbjct: 534 SESAVFHGFFSMP-EMRCQKLELLLMDNLRDKLRPIIISMNYSL---PLRMPD--RPRLG 587
Query: 752 VGSQDLFT-----------ASLPFEKNCGQDGLCEGDLGVTLSF--------SGLQTLTV 792
+ S D + + F+K CG D CE +L + +F S LQ
Sbjct: 588 LRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRD 647
Query: 793 GSSLELNVIV----TVWNAGEDSYGTVVSLYYPAGL 824
L L++ V T +GED++ +++L P L
Sbjct: 648 VRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPAL 683
>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
Length = 1066
Score = 156 bits (395), Expect = 9e-38
Identities = 139/516 (26%), Positives = 244/516 (47%), Gaps = 69/516 (13%)
Query: 350 MSQEGFSTALTMDGLFLGAVGSFSWSGGAFLYPPNMSPTFINMSQENVDMRDSYLGYSTE 409
M Q G S T + ++ GA G+++W G +++ ++ D + Y+GY+ +
Sbjct: 196 MCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDLSEYSYKDPEDQGNLYIGYTMQ 255
Query: 410 LALW----KGVQNLVLGAPRYQHTGKAVIFTQ-VSRQWRKKAEVTGTQIGSYFGASLCSV 464
+ + K + +V GAPR++H G + +Q R++ + G+Q+G+YFG+++
Sbjct: 256 VGSFILHPKNI-TIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIALA 314
Query: 465 DVDSDGSTDLILIGAPHYYEQTR--GGQVSVCPLPRG-RVQWQCDAVLRGEQGHPWGRFG 521
D+++DG DL L+GAP+Y+E+ GG + V G +L G G FG
Sbjct: 315 DLNNDGWQDL-LVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHGPSG---SAFG 370
Query: 522 AALTVLGDVNEDKLIDVAIGAPGEQENRGAVYLFHGASESGISPSHSQRIASSQLS-PRL 580
++ +GD+N+D D+A+GAP E G VY++H +S+ G+ Q I +L P L
Sbjct: 371 LSVASIGDINQDGFQDIAVGAP--FEGLGKVYIYHSSSK-GLLRQPQQVIHGEKLGLPGL 427
Query: 581 QYFGQALSGGQDLTQDGLMDLAVGA-RGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRCW 639
FG +LSG D+ ++ DL VG+ ++LLR+ PV+ + V++
Sbjct: 428 ATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINI--------------VHKTL 473
Query: 640 EEKPSALEAGDAT--------VCLTIQKSSLDQLGDIQSSVRFDLALDPGRLTSRAIFNE 691
+P+ L+ T +C +S+ + ++ + L D R R F
Sbjct: 474 VPRPAVLDPALCTATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRPPRLRFAG 533
Query: 692 TKNPTLTRRKTLGLGIHCETLKLLLPDCVEDVVSPIILHLNFSLVREPIPSPQNLRPVLA 751
+++ ++ + C+ L+LLL D + D + PII+ +N+SL P+ P RP L
Sbjct: 534 SESAVFHGFFSMP-EMRCQKLELLLMDNLRDKLRPIIISMNYSL---PLRMPD--RPRLG 587
Query: 752 VGSQDLFT-----------ASLPFEKNCGQDGLCEGDLGVTLSF--------SGLQTLTV 792
+ S D + + F+K CG D CE +L + +F S LQ
Sbjct: 588 LRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRD 647
Query: 793 GSSLELNVIV----TVWNAGEDSYGTVVSLYYPAGL 824
L L++ V T +GED++ +++L P L
Sbjct: 648 VRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPAL 683
>gi|49170034 integrin, alpha 8 [Homo sapiens]
Length = 1063
Score = 149 bits (376), Expect = 2e-35
Identities = 205/868 (23%), Positives = 364/868 (41%), Gaps = 116/868 (13%)
Query: 352 QEGFSTALTMDG-LFLGAVGSFSWSGGAFLYPPNMSPTFINMSQENVDMR---------- 400
Q GFS +G L +G GSF W G +++ N S +++ +
Sbjct: 201 QAGFSLDFYKNGDLIVGGPGSFYWQGQVIT--ASVADIIANYSFKDILRKLAGEKQTEVA 258
Query: 401 -----DSYLGYSTELALWKG--VQNLVLGAPR-YQHTGKAVIFTQVSRQWRKKAEVTGTQ 452
DSYLGYS + G Q LV G PR Q+ G I + + TG Q
Sbjct: 259 PASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINSTDMTFIQN--FTGEQ 316
Query: 453 IGSYFGASLCSVDVDSDGSTDLILIGAPHYYEQT------RGGQVSVCPLPRGRVQWQCD 506
+ SYFG ++ DV+SDG D +L+GAP + E+ GQ+ + L + ++
Sbjct: 317 MASYFGYTVVVSDVNSDGLDD-VLVGAPLFMEREFESNPREVGQIYLY-LQVSSLLFRDP 374
Query: 507 AVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAP-GEQENRGAVYLFHGASESGISP 565
+L G + +GRFG+A+ LGD+N+D D+AIG P ++ RG V +++G ++ G++
Sbjct: 375 QILTGTE--TFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNG-NKDGLNT 431
Query: 566 SHSQRIASSQLSPRL-QYFGQALSGGQDLTQDGLMDLAVGA--RGQVLLLRSLPVLKVGV 622
SQ + S + FG L G D+ ++ DL VGA G+V + R+ PV+ V
Sbjct: 432 KPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDA 491
Query: 623 AMRFSPVEVAKAVYRCWEEKPSALEAG---DATVCLTIQKSSLDQLGDIQSSVRFDLALD 679
+ P+ + C + P ++ + VC ++ S+ + + V+ D
Sbjct: 492 QLLLHPMIINLENKTC--QVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEVQLDSLKQ 549
Query: 680 PGRLTSRAIFNETKN-----PTLTRRKTLGLGIHCETLKLLLPDCVE--DVVSPIILHLN 732
G + R +F + P + +R+ C+ + L D E D +SPI + LN
Sbjct: 550 KGAI-KRTLFLDNHQAHRVFPLVIKRQK---SHQCQDFIVYLRDETEFRDKLSPINISLN 605
Query: 733 FSLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTLSFSGLQTLTV 792
+SL ++P+L +++ + +CG+D LC DL ++ Q + +
Sbjct: 606 YSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKHQVI-I 664
Query: 793 GSSLELNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTED 852
G L +I+ N GE +Y + + P + + ++ ++ L+CE +
Sbjct: 665 GDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGI----ERNNKGFRPLSCEY--KME 718
Query: 853 EGLRSSRCSVNHPIFHEGSNGTFIVTFDVS--YKATLGDRMLMRASASSENNKASSSKAT 910
R C + +P+ G+N + + F V K + ++ +S+++N S+ +
Sbjct: 719 NVTRMVVCDLGNPMV-SGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDN-PDSNFVS 776
Query: 911 FQLEL-PVKYAVYTMISRQEESTKYFNFATSDEKKMKE------AEHRYRVNNL------ 957
Q+ + V +S + + +E+ KE EH Y ++N+
Sbjct: 777 LQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTIS 836
Query: 958 ----------SQRDLAISINFWVPVL-------LNGVAVWDVVMEAPSQSLPCVSE---- 996
S RD + F + L + D+ A + P +S
Sbjct: 837 DTILEVGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRN 896
Query: 997 -------RKPPQHSDFLTQISRSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFG 1049
RK H + S + +L+C+ +CLQ C V E ++ L
Sbjct: 897 STIPHLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRL--- 953
Query: 1050 WVRETLQKK---VLVVSVAEITFDTSVYSQLPGQ--EAFMRAQMEMVLEEDEVYNAIP-- 1102
W LQ+K + S+ Y+ P + E + + ++ V +IP
Sbjct: 954 WAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLW 1013
Query: 1103 IIMGSSVGALLLLALITATLYKLGFFKR 1130
+I+ + + LL+LA++T L+K GFF R
Sbjct: 1014 VIILAILLGLLVLAILTLALWKCGFFDR 1041
>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
Length = 1002
Score = 147 bits (370), Expect = 7e-35
Identities = 205/862 (23%), Positives = 356/862 (41%), Gaps = 107/862 (12%)
Query: 352 QEGFSTALTM-DGLFLGAVGSFSWSGGAFL---------YPPNMSPTFINMSQENVDMR- 400
Q GFS T D + LG GSF W G Y PN+ N +
Sbjct: 140 QGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQA 199
Query: 401 ---DSYLGYSTELALWKG--VQNLVLGAPRYQHTGKAVIFTQVSRQWRKKAEVTGTQIGS 455
DSYLGYS + + G + + V G PR T +++ + TG Q+ +
Sbjct: 200 IFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAART-LGMVYIYDGKNMSSLYNFTGEQMAA 258
Query: 456 YFGASLCSVDVDSDGSTDLILIGAPHYYEQTRGG------QVSVCPLPRGRVQWQCDAVL 509
YFG S+ + D++ D D + IGAP + ++ G QVSV L R +Q +
Sbjct: 259 YFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVS-LQRASGDFQTTKLN 316
Query: 510 RGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAP-GEQENRGAVYLFHGASESGISPSHS 568
E + RFG+A+ LGD+++D D+AI AP G ++ +G VY+F+G S +G++ S
Sbjct: 317 GFEV---FARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAVPS 372
Query: 569 QRIASSQLSPRLQ--YFGQALSGGQDLTQDGLMDLAVGARG--QVLLLRSLPVLKVGVAM 624
Q I Q + R FG ++ G D+ ++G DL VGA G + +L R+ PV+ V +
Sbjct: 373 Q-ILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGL 431
Query: 625 RFSPVEVAKAVYRCWEEKPSALEAG--DATVCLTIQ-KSSLDQLGDIQSSVRFDLALDPG 681
P + + C +AL+ + CL K L + + Q + D G
Sbjct: 432 EVYPSILNQDNKTC-SLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKG 490
Query: 682 RLTSRAIFNETKNPTLTRRKTLGLG--IHCETLKLLLPDCVE--DVVSPIILHLNFSLVR 737
+ RA+F +++P+ ++ T+ G + CE L L D E D ++PI + + + L
Sbjct: 491 AI-RRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDY 549
Query: 738 EPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTLSFSGLQTLTVGSSLE 797
L+P+L + + +CG+D +C+ L V++ S + + +G
Sbjct: 550 RTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNP 608
Query: 798 LNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRS 857
L +IV N GE +Y + + P V + +++ RL+C TE++ R
Sbjct: 609 LTLIVKAQNQGEGAYEAELIVSIPLQADFIGV----VRNNEALARLSC-AFKTENQ-TRQ 662
Query: 858 SRCSVNHPI-------------FHEGSNGTFIVTFDVSYKAT---------LGDRMLMRA 895
C + +P+ H+ S V FD+ +++ + ++ +
Sbjct: 663 VVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAV 722
Query: 896 SASSENNKASSSKATFQLELPVKYAVYTMISRQEESTKYF---------NFATSDEKKMK 946
A+ E SS F LP+ + EE N +S K M
Sbjct: 723 LAAVEIRGVSSPDHIF---LPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAML 779
Query: 947 EAEHRYRVNN-----LSQRDLAISINFWVPVLLNGVAVWDVVMEAPSQSLPCVSERKPPQ 1001
+ Y+ NN + D+ +N + +N + + ++ ++ V+ +
Sbjct: 780 HLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKN-DTVAGQGERD 838
Query: 1002 H----SDFLTQISRSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQK 1057
H D L C +A CL+ C V + +K L W + K
Sbjct: 839 HLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLL---WTETFMNK 895
Query: 1058 K-----VLVVSVAEITFDTSVYSQLPGQE----AFMRAQMEMVLEEDEVYNAIPIIMGSS 1108
+ + S A Y LP ++ + + ++ + + +I+ +
Sbjct: 896 ENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAV 955
Query: 1109 VGALLLLALITATLYKLGFFKR 1130
+ LLLLA++ +Y++GFFKR
Sbjct: 956 LAGLLLLAVLVFVMYRMGFFKR 977
>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
Length = 1048
Score = 147 bits (370), Expect = 7e-35
Identities = 205/862 (23%), Positives = 356/862 (41%), Gaps = 107/862 (12%)
Query: 352 QEGFSTALTM-DGLFLGAVGSFSWSGGAFL---------YPPNMSPTFINMSQENVDMR- 400
Q GFS T D + LG GSF W G Y PN+ N +
Sbjct: 186 QGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQA 245
Query: 401 ---DSYLGYSTELALWKG--VQNLVLGAPRYQHTGKAVIFTQVSRQWRKKAEVTGTQIGS 455
DSYLGYS + + G + + V G PR T +++ + TG Q+ +
Sbjct: 246 IFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAART-LGMVYIYDGKNMSSLYNFTGEQMAA 304
Query: 456 YFGASLCSVDVDSDGSTDLILIGAPHYYEQTRGG------QVSVCPLPRGRVQWQCDAVL 509
YFG S+ + D++ D D + IGAP + ++ G QVSV L R +Q +
Sbjct: 305 YFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVS-LQRASGDFQTTKLN 362
Query: 510 RGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAP-GEQENRGAVYLFHGASESGISPSHS 568
E + RFG+A+ LGD+++D D+AI AP G ++ +G VY+F+G S +G++ S
Sbjct: 363 GFEV---FARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAVPS 418
Query: 569 QRIASSQLSPRLQ--YFGQALSGGQDLTQDGLMDLAVGARG--QVLLLRSLPVLKVGVAM 624
Q I Q + R FG ++ G D+ ++G DL VGA G + +L R+ PV+ V +
Sbjct: 419 Q-ILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGL 477
Query: 625 RFSPVEVAKAVYRCWEEKPSALEAG--DATVCLTIQ-KSSLDQLGDIQSSVRFDLALDPG 681
P + + C +AL+ + CL K L + + Q + D G
Sbjct: 478 EVYPSILNQDNKTC-SLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKG 536
Query: 682 RLTSRAIFNETKNPTLTRRKTLGLG--IHCETLKLLLPDCVE--DVVSPIILHLNFSLVR 737
+ RA+F +++P+ ++ T+ G + CE L L D E D ++PI + + + L
Sbjct: 537 AI-RRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDY 595
Query: 738 EPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTLSFSGLQTLTVGSSLE 797
L+P+L + + +CG+D +C+ L V++ S + + +G
Sbjct: 596 RTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNP 654
Query: 798 LNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRS 857
L +IV N GE +Y + + P V + +++ RL+C TE++ R
Sbjct: 655 LTLIVKAQNQGEGAYEAELIVSIPLQADFIGV----VRNNEALARLSC-AFKTENQ-TRQ 708
Query: 858 SRCSVNHPI-------------FHEGSNGTFIVTFDVSYKAT---------LGDRMLMRA 895
C + +P+ H+ S V FD+ +++ + ++ +
Sbjct: 709 VVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAV 768
Query: 896 SASSENNKASSSKATFQLELPVKYAVYTMISRQEESTKYF---------NFATSDEKKMK 946
A+ E SS F LP+ + EE N +S K M
Sbjct: 769 LAAVEIRGVSSPDHIF---LPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAML 825
Query: 947 EAEHRYRVNN-----LSQRDLAISINFWVPVLLNGVAVWDVVMEAPSQSLPCVSERKPPQ 1001
+ Y+ NN + D+ +N + +N + + ++ ++ V+ +
Sbjct: 826 HLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKN-DTVAGQGERD 884
Query: 1002 H----SDFLTQISRSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQK 1057
H D L C +A CL+ C V + +K L W + K
Sbjct: 885 HLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLL---WTETFMNK 941
Query: 1058 K-----VLVVSVAEITFDTSVYSQLPGQE----AFMRAQMEMVLEEDEVYNAIPIIMGSS 1108
+ + S A Y LP ++ + + ++ + + +I+ +
Sbjct: 942 ENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAV 1001
Query: 1109 VGALLLLALITATLYKLGFFKR 1130
+ LLLLA++ +Y++GFFKR
Sbjct: 1002 LAGLLLLAVLVFVMYRMGFFKR 1023
Score = 32.3 bits (72), Expect = 2.7
Identities = 39/133 (29%), Positives = 54/133 (40%), Gaps = 29/133 (21%)
Query: 4 GTVLLLS--VLASYHGFNLDVEEPTIFQEDAGGFGQSVVQF----GGSR--LVVGAPLEV 55
G LLLS +L FNLDV+ P + G + V F SR L+VGAP
Sbjct: 15 GLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAP--- 71
Query: 56 VAANQT-------GRLYDCA-AATGMCQPIPL-------HIRPEAVNMSLGLTLAASTNG 100
AN T G++ C ++T CQPI + + + + AS
Sbjct: 72 -KANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRS 130
Query: 101 --SRLLACGPTLH 111
++LAC P H
Sbjct: 131 KQDKILACAPLYH 143
>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
Length = 1012
Score = 139 bits (349), Expect = 2e-32
Identities = 188/799 (23%), Positives = 336/799 (42%), Gaps = 93/799 (11%)
Query: 401 DSYLGYSTELALWKG--VQNLVLGAPRYQHTGKAVIFTQVSRQWRKKAEVTGTQIGSYFG 458
DSYLGYS + + G + + V G PR T +++ + TG Q+ +YFG
Sbjct: 213 DSYLGYSVAVGDFNGDGIDDFVSGVPRAART-LGMVYIYDGKNMSSLYNFTGEQMAAYFG 271
Query: 459 ASLCSVDVDSDGSTDLILIGAPHYYEQTRGG------QVSVCPLPRGRVQWQCDAVLRGE 512
S+ + D++ D D + IGAP + ++ G QVSV L R +Q + E
Sbjct: 272 FSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVS-LQRASGDFQTTKLNGFE 329
Query: 513 QGHPWGRFGAALTVLGDVNEDKLIDVAIGAP-GEQENRGAVYLFHGASESGISPSHSQRI 571
+ RFG+A+ LGD+++D D+AI AP G ++ +G VY+F+G S +G++ SQ I
Sbjct: 330 V---FARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS-TGLNAVPSQ-I 384
Query: 572 ASSQLSPRLQ--YFGQALSGGQDLTQDGLMDLAVGARG--QVLLLRSLPVLKVGVAMRFS 627
Q + R FG ++ G D+ ++G DL VGA G + +L R+ PV+ V +
Sbjct: 385 LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY 444
Query: 628 PVEVAKAVYRCWEEKPSALEAG--DATVCLTIQ-KSSLDQLGDIQSSVRFDLALDPGRLT 684
P + + C +AL+ + CL K L + + Q + D G +
Sbjct: 445 PSILNQDNKTC-SLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAI- 502
Query: 685 SRAIFNETKNPTLTRRKTLGLG--IHCETLKLLLPDCVE--DVVSPIILHLNFSLVREPI 740
RA+F +++P+ ++ T+ G + CE L L D E D ++PI + + + L
Sbjct: 503 RRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTA 562
Query: 741 PSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTLSFSGLQTLTVGSSLELNV 800
L+P+L + + +CG+D +C+ L V++ S + + +G L +
Sbjct: 563 ADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD-SDQKKIYIGDDNPLTL 621
Query: 801 IVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSRC 860
IV N GE +Y + + P V + +++ RL+C TE++ R C
Sbjct: 622 IVKAQNQGEGAYEAELIVSIPLQADFIGV----VRNNEALARLSC-AFKTENQ-TRQVVC 675
Query: 861 SVNHPI-------------FHEGSNGTFIVTFDVSYKAT---------LGDRMLMRASAS 898
+ +P+ H+ S V FD+ +++ + ++ + A+
Sbjct: 676 DLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAA 735
Query: 899 SENNKASSSKATFQLELPVKYAVYTMISRQEESTKYF---------NFATSDEKKMKEAE 949
E SS F LP+ + EE N +S K M +
Sbjct: 736 VEIRGVSSPDHIF---LPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQ 792
Query: 950 HRYRVNN-----LSQRDLAISINFWVPVLLNGVAVWDVVMEAPSQSLPCVSERKPPQH-- 1002
Y+ NN + D+ +N + +N + + ++ ++ V+ + H
Sbjct: 793 WPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKN-DTVAGQGERDHLI 851
Query: 1003 --SDFLTQISRSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKK-- 1058
D L C +A CL+ C V + +K L W + K+
Sbjct: 852 TKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLL---WTETFMNKENQ 908
Query: 1059 ---VLVVSVAEITFDTSVYSQLPGQE----AFMRAQMEMVLEEDEVYNAIPIIMGSSVGA 1111
+ S A Y LP ++ + + ++ + + +I+ + +
Sbjct: 909 NHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAG 968
Query: 1112 LLLLALITATLYKLGFFKR 1130
LLLLA++ +Y++GFFKR
Sbjct: 969 LLLLAVLVFVMYRMGFFKR 987
Score = 32.3 bits (72), Expect = 2.7
Identities = 39/133 (29%), Positives = 54/133 (40%), Gaps = 29/133 (21%)
Query: 4 GTVLLLS--VLASYHGFNLDVEEPTIFQEDAGGFGQSVVQF----GGSR--LVVGAPLEV 55
G LLLS +L FNLDV+ P + G + V F SR L+VGAP
Sbjct: 15 GLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAP--- 71
Query: 56 VAANQT-------GRLYDCA-AATGMCQPIPL-------HIRPEAVNMSLGLTLAASTNG 100
AN T G++ C ++T CQPI + + + + AS
Sbjct: 72 -KANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRS 130
Query: 101 --SRLLACGPTLH 111
++LAC P H
Sbjct: 131 KQDKILACAPLYH 143
>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
Length = 1137
Score = 129 bits (323), Expect = 2e-29
Identities = 222/929 (23%), Positives = 377/929 (40%), Gaps = 183/929 (19%)
Query: 339 QSRASSSFQHEMSQEGFSTALTMDGLFL--GAVGSFSWSGGAFLYPPNMSPTFINMSQEN 396
+ R Q Q+G + A + D +L GA G+++W G F+ + S + +
Sbjct: 185 EGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDPD-QLVYKT 243
Query: 397 VDMRD------------SYLGYSTELALWKGVQ-----NLVLGAPRYQHTGKAVIFTQVS 439
+D D SYLG+S + KG+ + V GAPR H G VI + S
Sbjct: 244 LDPADRLPGPAGDLALNSYLGFSIDSG--KGLVRAEELSFVAGAPRANHKGAVVILRKDS 301
Query: 440 RQWRKKAEV--TGTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYEQTR--GGQVSVCP 495
R EV +G ++ S FG SL D++SDG DLI +GAP+++E+ GG V V
Sbjct: 302 AS-RLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVYL 359
Query: 496 LPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAPGEQENRGAVYLF 555
G W + LR G P FG +L VLGD+N+D D+A+GAP + + G V+++
Sbjct: 360 NQGGH--WAGISPLR-LCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIY 414
Query: 556 HGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVGARGQ-VLLLRS 614
HG+S G+ SQ + + ++ FG +LSG D+ + DL VG+ +L R+
Sbjct: 415 HGSS-LGVVAKPSQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRA 471
Query: 615 LPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQK--SSLDQLGDIQSSV 672
P+L V + +P + C AG +VC+ ++ S + +V
Sbjct: 472 RPILHVSHEVSIAPRSIDLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSYSPTV 522
Query: 673 RFDLALDPGRLTSRAIFNETKNPTLTRRK----------TLGLGIH----CETLKLLLPD 718
D LD T R + + T R T+ L C L +
Sbjct: 523 ALDYVLDAD--TDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQE 580
Query: 719 CVEDVVSPIILHLNFSL----VREPIPSP--QNLRPVLAVGSQDLFTASLPF-EKNCGQD 771
V+D + I++ L++SL +R P + P+L A + F ++ CG+D
Sbjct: 581 NVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGED 640
Query: 772 GLCEGDLGVTLS--------------------FSGLQTLTVGSSLELNVIVTVWNA---- 807
+C+ +L + + + L L+ + L ++VT +
Sbjct: 641 KICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQ 700
Query: 808 ----GEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSRCSVN 863
G+D++ + + P L + V AL A + + +E C +
Sbjct: 701 PQADGDDAHEAQLLVMLPDSLHYSGV---------RALDPAEKPLCLSNENASHVECELG 751
Query: 864 HPIFHEGSNGTF---IVTFDVSYKATLGDRMLMRASASSENNKASSSKATFQLELPVKYA 920
+P+ G+ TF + T +S + T + L+ A+ S + S++A +ELP+ A
Sbjct: 752 NPM-KRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIA 810
Query: 921 VYTMISRQEESTKYFNFATSDEKKMK-------EAEHRYRVNNLSQRDLAISINF----W 969
+ +F+ E+ M+ + ++ V+N Q + F W
Sbjct: 811 GMAI-----PQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMW 865
Query: 970 VPVLLNG----------------------------VAVWDV--------VMEAPSQSLPC 993
+ NG + DV +E P Q P
Sbjct: 866 PHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEP- 924
Query: 994 VSERKPPQHSDF---LTQISRSPMLDCS--IADCLQFRCDVPSFSVQEELDFTLKGNLSF 1048
ER+ P S + + ++ LDC+ A+C+ F C P +S + G L
Sbjct: 925 -GERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSC--PLYSFDRAAVLHVWGRL-- 979
Query: 1049 GWVRETLQ-----KKVLVVSVAEITFDTSVYSQLPGQEAFMRAQMEMVLEEDEVYNAIP- 1102
W L+ K + V+ A IT +S+ + + + + M + V +P
Sbjct: 980 -WNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPW 1038
Query: 1103 -IIMGSSVGALLLLALITATLYKLGFFKR 1130
+I+ + + LL+LAL+ L+K+GFFKR
Sbjct: 1039 WVILLAVLAGLLVLALLVLLLWKMGFFKR 1067
>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo
sapiens]
Length = 1073
Score = 127 bits (319), Expect = 6e-29
Identities = 204/901 (22%), Positives = 377/901 (41%), Gaps = 159/901 (17%)
Query: 352 QEGFSTALTMDGLFL--GAVGSFSWSGGAFLYPPNMSPTFINMSQENVDM---------- 399
Q+G + T D ++ GA G+++W G + N + +N+ ++
Sbjct: 189 QQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDES 248
Query: 400 -----RDSYLGYSTELALWKGVQN-----LVLGAPRYQHTGKAVIFTQVSRQWRKKAE-- 447
+SYLG+S + KG+ + V GAPR H+G V+ + + E
Sbjct: 249 LVPVPANSYLGFSLDSG--KGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHI 306
Query: 448 VTGTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYEQTR--GGQVSVCPLPRGRVQWQC 505
G + S FG + VD++ DG D++ IGAP Y+++ GG V V +GR W
Sbjct: 307 FDGEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYMNQQGR--WNN 363
Query: 506 DAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAPGEQENRGAVYLFHGASESGISP 565
+R G FG A+ +GD+N+D D+A+GAP ++ G V+++HG S +GI+
Sbjct: 364 VKPIR-LNGTKDSMFGIAVKNIGDINQDGYPDIAVGAP--YDDLGKVFIYHG-SANGINT 419
Query: 566 SHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVGA-RGQVLLLRSLPVLKVGVAM 624
+Q + +SP YFG +++G DL ++ D+AVG+ V + RS PV+ + +
Sbjct: 420 KPTQVLKG--ISP---YFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTI 474
Query: 625 RFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQKSSLDQLGD---------IQSSVRFD 675
+P + + + + +CL + KS + + I ++ +
Sbjct: 475 TVTPNRI--------DLRQKTACGAPSGICLQV-KSCFEYTANPAGYNPSISIVGTLEAE 525
Query: 676 LALDPGRLTSRAIF-NETKNPTLTRRKTLGLGIH--CETLKLLLPDCVEDVVSPIILHLN 732
L+SR F N+ P T+ TL C L L D + D + PI + +
Sbjct: 526 KERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITAS 585
Query: 733 FSL----VREPIPSPQNLRPVLAVGSQDLFTASLP---FEKNCGQDGLCEGDLGVTLSF- 784
+ R + S + P+L S + TA + ++ CG D +C +L + F
Sbjct: 586 VEIQEPSSRRRVNSLPEVLPIL--NSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFC 643
Query: 785 ---------------SGLQTLTVGSSLELNVIVTVWNA----------GEDSYGTVVSLY 819
G+ L + ++ + +TV N+ G+D++ +
Sbjct: 644 TREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIAT 703
Query: 820 YPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSRCSVNHPIFHEGSNGTF---I 876
+P L++ + P + +L+C ++ + C + +P F SN TF +
Sbjct: 704 FPDTLTYSAYRELRAFPEK---QLSC----VANQNGSQADCELGNP-FKRNSNVTFYLVL 755
Query: 877 VTFDVSYKATLGDRMLMRASASSENNKAS-SSKATFQLELPVKYAVYTMISRQEESTKYF 935
T +V++ D L + S+++N A ++KA +EL + ++ + S YF
Sbjct: 756 STTEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIEL-----LLSVSGVAKPSQVYF 810
Query: 936 NFATSDEKKMKE-------AEHRYRVNNLSQRDLAI---SINF-WVPVLLNGV-AVWDVV 983
E+ MK E+ +RV NL + + ++N W + NG ++ V
Sbjct: 811 GGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVK 870
Query: 984 MEAPS-QSLPC----------------------VSERKPPQHSDFLTQISRS-PMLDCSI 1019
+E+ + + C ++E++ + F R L+CS+
Sbjct: 871 VESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSV 930
Query: 1020 -ADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQ-- 1076
+C+ RC P + + L+ L E K + + D + ++
Sbjct: 931 NVNCVNIRC--PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENI 988
Query: 1077 -LPGQEAFMRAQMEMVLEEDEVYNAIP--IIMGSSVGALLLLALITATLYKLGFFKRHYK 1133
LP +R + + Y+ +P II+ + + +L+LAL+ L+K GFFKR+ K
Sbjct: 989 RLPNAGTQVRVTV-FPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNKK 1047
Query: 1134 E 1134
+
Sbjct: 1048 D 1048
Score = 33.5 bits (75), Expect = 1.2
Identities = 36/118 (30%), Positives = 54/118 (45%), Gaps = 21/118 (17%)
Query: 8 LLSVLASYHGFNLDVEEPTIFQE--DAGG-FGQSVVQFGGSR------LVVGAP----LE 54
LLS L + FNLD E + ++ D G FG S+ + L+VGAP L
Sbjct: 16 LLSRLGA--AFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALP 73
Query: 55 VVAANQTGRLYDC-AAATGMCQPIPLHIRPEAVNMS-----LGLTLAASTNGSRLLAC 106
+ AN+TG LY C A G C I + + S +G+T+ + G +++ C
Sbjct: 74 LQRANRTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTC 131
>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo
sapiens]
Length = 1091
Score = 125 bits (313), Expect = 3e-28
Identities = 203/897 (22%), Positives = 374/897 (41%), Gaps = 159/897 (17%)
Query: 352 QEGFSTALTMDGLFL--GAVGSFSWSGGAFLYPPNMSPTFINMSQENVDM---------- 399
Q+G + T D ++ GA G+++W G + N + +N+ ++
Sbjct: 189 QQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDES 248
Query: 400 -----RDSYLGYSTELALWKGVQN-----LVLGAPRYQHTGKAVIFTQVSRQWRKKAE-- 447
+SYLG+S + KG+ + V GAPR H+G V+ + + E
Sbjct: 249 LVPVPANSYLGFSLDSG--KGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHI 306
Query: 448 VTGTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYEQTR--GGQVSVCPLPRGRVQWQC 505
G + S FG + VD++ DG D++ IGAP Y+++ GG V V +GR W
Sbjct: 307 FDGEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYMNQQGR--WNN 363
Query: 506 DAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAPGEQENRGAVYLFHGASESGISP 565
+R G FG A+ +GD+N+D D+A+GAP ++ G V+++HG S +GI+
Sbjct: 364 VKPIR-LNGTKDSMFGIAVKNIGDINQDGYPDIAVGAP--YDDLGKVFIYHG-SANGINT 419
Query: 566 SHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVGA-RGQVLLLRSLPVLKVGVAM 624
+Q + +SP YFG +++G DL ++ D+AVG+ V + RS PV+ + +
Sbjct: 420 KPTQVLKG--ISP---YFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTI 474
Query: 625 RFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQKSSLDQLGD---------IQSSVRFD 675
+P + + + + +CL + KS + + I ++ +
Sbjct: 475 TVTPNRI--------DLRQKTACGAPSGICLQV-KSCFEYTANPAGYNPSISIVGTLEAE 525
Query: 676 LALDPGRLTSRAIF-NETKNPTLTRRKTLGLGIH--CETLKLLLPDCVEDVVSPIILHLN 732
L+SR F N+ P T+ TL C L L D + D + PI + +
Sbjct: 526 KERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITAS 585
Query: 733 FSL----VREPIPSPQNLRPVLAVGSQDLFTASLP---FEKNCGQDGLCEGDLGVTLSF- 784
+ R + S + P+L S + TA + ++ CG D +C +L + F
Sbjct: 586 VEIQEPSSRRRVNSLPEVLPIL--NSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFC 643
Query: 785 ---------------SGLQTLTVGSSLELNVIVTVWNA----------GEDSYGTVVSLY 819
G+ L + ++ + +TV N+ G+D++ +
Sbjct: 644 TREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIAT 703
Query: 820 YPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSRCSVNHPIFHEGSNGTF---I 876
+P L++ + P + +L+C ++ + C + +P F SN TF +
Sbjct: 704 FPDTLTYSAYRELRAFPEK---QLSC----VANQNGSQADCELGNP-FKRNSNVTFYLVL 755
Query: 877 VTFDVSYKATLGDRMLMRASASSENNKAS-SSKATFQLELPVKYAVYTMISRQEESTKYF 935
T +V++ D L + S+++N A ++KA +EL + ++ + S YF
Sbjct: 756 STTEVTFDTPDLDINLKLETTSNQDNLAPITAKAKVVIEL-----LLSVSGVAKPSQVYF 810
Query: 936 NFATSDEKKMKE-------AEHRYRVNNLSQRDLAI---SINF-WVPVLLNGV-AVWDVV 983
E+ MK E+ +RV NL + + ++N W + NG ++ V
Sbjct: 811 GGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVK 870
Query: 984 MEAPS-QSLPC----------------------VSERKPPQHSDFLTQISRS-PMLDCSI 1019
+E+ + + C ++E++ + F R L+CS+
Sbjct: 871 VESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSV 930
Query: 1020 -ADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQ-- 1076
+C+ RC P + + L+ L E K + + D + ++
Sbjct: 931 NVNCVNIRC--PLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENI 988
Query: 1077 -LPGQEAFMRAQMEMVLEEDEVYNAIP--IIMGSSVGALLLLALITATLYKLGFFKR 1130
LP +R + + Y+ +P II+ + + +L+LAL+ L+K GFFKR
Sbjct: 989 RLPNAGTQVRVTV-FPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKR 1044
Score = 33.5 bits (75), Expect = 1.2
Identities = 36/118 (30%), Positives = 54/118 (45%), Gaps = 21/118 (17%)
Query: 8 LLSVLASYHGFNLDVEEPTIFQE--DAGG-FGQSVVQFGGSR------LVVGAP----LE 54
LLS L + FNLD E + ++ D G FG S+ + L+VGAP L
Sbjct: 16 LLSRLGA--AFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALP 73
Query: 55 VVAANQTGRLYDC-AAATGMCQPIPLHIRPEAVNMS-----LGLTLAASTNGSRLLAC 106
+ AN+TG LY C A G C I + + S +G+T+ + G +++ C
Sbjct: 74 LQRANRTGGLYSCDITARGPCTRIEFDNDADPTSESKEDQWMGVTVQSQGPGGKVVTC 131
>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
Length = 1044
Score = 124 bits (310), Expect = 7e-28
Identities = 223/933 (23%), Positives = 376/933 (40%), Gaps = 187/933 (20%)
Query: 339 QSRASSSFQHEMSQEGFSTALTMDGLFL--GAVGSFSWSG----------GAFLYPPNMS 386
+ R Q Q+G + A + D +L GA G+++W G A L +
Sbjct: 88 EGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDG 147
Query: 387 PTFINMSQENVDMR------DSYLGYSTELALWKGVQ-----NLVLGAPRYQHTGKAVIF 435
P +E D R +SY G+S + KG+ + V GAPR H G VI
Sbjct: 148 PYEAGGEKEQ-DPRLIPVPANSYFGFSIDSG--KGLVRAEELSFVAGAPRANHKGAVVIL 204
Query: 436 TQVSRQWRKKAEV--TGTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYEQTR--GGQV 491
+ S R EV +G ++ S FG SL D++SDG DLI +GAP+++E+ GG V
Sbjct: 205 RKDSAS-RLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAV 262
Query: 492 SVCPLPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAPGEQENRGA 551
V G W + LR G P FG +L VLGD+N+D D+A+GAP + + G
Sbjct: 263 YVYLNQGGH--WAGISPLR-LCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GK 317
Query: 552 VYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVGARGQ-VL 610
V+++HG+S G+ SQ + + ++ FG +LSG D+ + DL VG+ +
Sbjct: 318 VFIYHGSS-LGVVAKPSQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAV 374
Query: 611 LLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQK--SSLDQLGDI 668
L R+ P+L V + +P + C AG +VC+ ++ S +
Sbjct: 375 LFRARPILHVSHEVSIAPRSIDLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSY 425
Query: 669 QSSVRFDLALDPGRLTSRAIFNETKNPTLTRRK----------TLGLGIH----CETLKL 714
+V D LD T R + + T R T+ L C
Sbjct: 426 SPTVALDYVLDAD--TDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMF 483
Query: 715 LLPDCVEDVVSPIILHLNFSL----VREPIPSP--QNLRPVLAVGSQDLFTASLPF-EKN 767
L + V+D + I++ L++SL +R P + P+L A + F ++
Sbjct: 484 QLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQG 543
Query: 768 CGQDGLCEGDLGVTLS--------------------FSGLQTLTVGSSLELNVIVTVWNA 807
CG+D +C+ +L + + + L L+ + L ++VT +
Sbjct: 544 CGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPS 603
Query: 808 --------GEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSR 859
G+D++ + + P L + V AL A + + +E
Sbjct: 604 DPAQPQADGDDAHEAQLLVMLPDSLHYSGV---------RALDPAEKPLCLSNENASHVE 654
Query: 860 CSVNHPIFHEGSNGTF---IVTFDVSYKATLGDRMLMRASASSENNKASSSKATFQLELP 916
C + +P+ G+ TF + T +S + T + L+ A+ S + S++A +ELP
Sbjct: 655 CELGNPM-KRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELP 713
Query: 917 VKYAVYTMISRQEESTKYFNFATSDEKKMK-------EAEHRYRVNNLSQRDLAISINF- 968
+ A + +F+ E+ M+ + ++ V+N Q + F
Sbjct: 714 LSIAGMAI-----PQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFL 768
Query: 969 ---WVPVLLNG----------------------------VAVWDV--------VMEAPSQ 989
W + NG + DV +E P Q
Sbjct: 769 NIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQ 828
Query: 990 SLPCVSERKPPQHSDF---LTQISRSPMLDCS--IADCLQFRCDVPSFSVQEELDFTLKG 1044
P ER+ P S + + ++ LDC+ A+C+ F C P +S + G
Sbjct: 829 QEP--GERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSC--PLYSFDRAAVLHVWG 884
Query: 1045 NLSFGWVRETLQ-----KKVLVVSVAEITFDTSVYSQLPGQEAFMRAQMEMVLEEDEVYN 1099
L W L+ K + V+ A IT +S+ + + + + M + V
Sbjct: 885 RL---WNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAE 941
Query: 1100 AIP--IIMGSSVGALLLLALITATLYKLGFFKR 1130
+P +I+ + + LL+LAL+ L+K+GFFKR
Sbjct: 942 GVPWWVILLAVLAGLLVLALLVLLLWKMGFFKR 974
>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
Length = 1141
Score = 124 bits (310), Expect = 7e-28
Identities = 223/933 (23%), Positives = 376/933 (40%), Gaps = 187/933 (20%)
Query: 339 QSRASSSFQHEMSQEGFSTALTMDGLFL--GAVGSFSWSG----------GAFLYPPNMS 386
+ R Q Q+G + A + D +L GA G+++W G A L +
Sbjct: 185 EGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDG 244
Query: 387 PTFINMSQENVDMR------DSYLGYSTELALWKGVQ-----NLVLGAPRYQHTGKAVIF 435
P +E D R +SY G+S + KG+ + V GAPR H G VI
Sbjct: 245 PYEAGGEKEQ-DPRLIPVPANSYFGFSIDSG--KGLVRAEELSFVAGAPRANHKGAVVIL 301
Query: 436 TQVSRQWRKKAEV--TGTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYEQTR--GGQV 491
+ S R EV +G ++ S FG SL D++SDG DLI +GAP+++E+ GG V
Sbjct: 302 RKDSAS-RLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAV 359
Query: 492 SVCPLPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAPGEQENRGA 551
V G W + LR G P FG +L VLGD+N+D D+A+GAP + + G
Sbjct: 360 YVYLNQGGH--WAGISPLR-LCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GK 414
Query: 552 VYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVGARGQ-VL 610
V+++HG+S G+ SQ + + ++ FG +LSG D+ + DL VG+ +
Sbjct: 415 VFIYHGSS-LGVVAKPSQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAV 471
Query: 611 LLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQK--SSLDQLGDI 668
L R+ P+L V + +P + C AG +VC+ ++ S +
Sbjct: 472 LFRARPILHVSHEVSIAPRSIDLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSY 522
Query: 669 QSSVRFDLALDPGRLTSRAIFNETKNPTLTRRK----------TLGLGIH----CETLKL 714
+V D LD T R + + T R T+ L C
Sbjct: 523 SPTVALDYVLDAD--TDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMF 580
Query: 715 LLPDCVEDVVSPIILHLNFSL----VREPIPSP--QNLRPVLAVGSQDLFTASLPF-EKN 767
L + V+D + I++ L++SL +R P + P+L A + F ++
Sbjct: 581 QLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQG 640
Query: 768 CGQDGLCEGDLGVTLS--------------------FSGLQTLTVGSSLELNVIVTVWNA 807
CG+D +C+ +L + + + L L+ + L ++VT +
Sbjct: 641 CGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPS 700
Query: 808 --------GEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSR 859
G+D++ + + P L + V AL A + + +E
Sbjct: 701 DPAQPQADGDDAHEAQLLVMLPDSLHYSGV---------RALDPAEKPLCLSNENASHVE 751
Query: 860 CSVNHPIFHEGSNGTF---IVTFDVSYKATLGDRMLMRASASSENNKASSSKATFQLELP 916
C + +P+ G+ TF + T +S + T + L+ A+ S + S++A +ELP
Sbjct: 752 CELGNPM-KRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELP 810
Query: 917 VKYAVYTMISRQEESTKYFNFATSDEKKMK-------EAEHRYRVNNLSQRDLAISINF- 968
+ A + +F+ E+ M+ + ++ V+N Q + F
Sbjct: 811 LSIAGMAI-----PQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFL 865
Query: 969 ---WVPVLLNG----------------------------VAVWDV--------VMEAPSQ 989
W + NG + DV +E P Q
Sbjct: 866 NIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQ 925
Query: 990 SLPCVSERKPPQHSDF---LTQISRSPMLDCS--IADCLQFRCDVPSFSVQEELDFTLKG 1044
P ER+ P S + + ++ LDC+ A+C+ F C P +S + G
Sbjct: 926 QEP--GERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSC--PLYSFDRAAVLHVWG 981
Query: 1045 NLSFGWVRETLQ-----KKVLVVSVAEITFDTSVYSQLPGQEAFMRAQMEMVLEEDEVYN 1099
L W L+ K + V+ A IT +S+ + + + + M + V
Sbjct: 982 RL---WNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAE 1038
Query: 1100 AIP--IIMGSSVGALLLLALITATLYKLGFFKR 1130
+P +I+ + + LL+LAL+ L+K+GFFKR
Sbjct: 1039 GVPWWVILLAVLAGLLVLALLVLLLWKMGFFKR 1071
>gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens]
Length = 496
Score = 93.6 bits (231), Expect = 1e-18
Identities = 65/213 (30%), Positives = 106/213 (49%), Gaps = 11/213 (5%)
Query: 150 DIVFLIDGSGSIDQNDFNQMKGFVQAVMGQFEGTDTL--FALMQYSNLLKIHFTFTQFRT 207
D+VFLIDGS S+ +F +K F+ ++ + +D L L+QYS+ ++ F +F T
Sbjct: 275 DLVFLIDGSKSVRPENFELVKKFISQIVDTLDVSDKLAQVGLVQYSSSVRQEFPLGRFHT 334
Query: 208 SPSQQSLVDPIVQLKGLTFTATGILTVVTQLFHHKNGARKSAKKILIVITDGQKYKDPLE 267
++ V + ++ T T + ++ F +GAR A+K+ IV TDG+
Sbjct: 335 KKDIKAAVRNMSYMEKGTMTGAALKYLIDNSFTVSSGARPGAQKVGIVFTDGRSQD---Y 391
Query: 268 YSDVIPQAEKAGIIRYAIGVGHAFQGPTARQELNTISSAPPQDHVFKVDNFAALGSIQKQ 327
+D +A+ G +A+GVG+A + EL I+S P +H F +F + I K+
Sbjct: 392 INDAAKKAKDLGFKMFAVGVGNAVE-----DELREIASEPVAEHYFYTADFKTINQIGKK 446
Query: 328 LQEKIYAVEGTQSRASSSFQHEMSQEGFSTALT 360
LQ+KI VE S + + EG ALT
Sbjct: 447 LQKKI-CVEEDPCACESLVKFQAKVEGLLQALT 478
Score = 71.2 bits (173), Expect = 5e-12
Identities = 64/262 (24%), Positives = 119/262 (45%), Gaps = 21/262 (8%)
Query: 122 GSCLLLGSRWEIIQTV--PDATPE-----CPHQEMDIVFLIDGSGSIDQNDFNQMKGFVQ 174
G+ L+L S ++Q + P P+ C + D+VF++D S S+ +F ++K F+
Sbjct: 6 GTSLMLCSLLLLLQALCSPGLAPQSRGHLCRTRPTDLVFVVDSSRSVRPVEFEKVKVFLS 65
Query: 175 AVMGQFE--GTDTLFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGLTFTATGIL 232
V+ + T ++ Y++ +K F+ + + V I L T T I
Sbjct: 66 QVIESLDVGPNATRVGMVNYASTVKQEFSLRAHVSKAALLQAVRRIQPLSTGTMTGLAIQ 125
Query: 233 TVVTQLFHHKNGARKSA---KKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGVGH 289
+T+ F G R + K++IV+TDG+ +D ++ DV +A +G+ +AIGV
Sbjct: 126 FAITKAFGDAEGGRSRSPDISKVVIVVTDGRP-QDSVQ--DVSARARASGVELFAIGV-- 180
Query: 290 AFQGPTARQELNTISSAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRASSSFQHE 349
G + L I+S P +HV V++++ + + ++ QE V + +
Sbjct: 181 ---GSVDKATLRQIASEPQDEHVDYVESYSVIEKLSRKFQEAFCVVSDLCATGDHDCEQV 237
Query: 350 -MSQEGFSTALTMDGLFLGAVG 370
+S G T +G L + G
Sbjct: 238 CISSPGSYTCACHEGFTLNSDG 259
>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
Length = 1796
Score = 87.8 bits (216), Expect = 5e-17
Identities = 61/196 (31%), Positives = 98/196 (50%), Gaps = 11/196 (5%)
Query: 136 TVPDATPECPHQEMDIVFLIDGSGSIDQNDFNQMKGFVQAVMGQFE--GTD-TLFALMQY 192
T+P A C + D+VF++DGS SI +FN++ F+ + +G GTD T A++Q+
Sbjct: 1018 TIPPAKEVCKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQF 1077
Query: 193 SNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGLTFTATGILTVVTQLFHHKNGARKSAKKI 252
++ + F ++T + + I G T T I V LF ++G R+ K+
Sbjct: 1078 TDDPRTEFKLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTRRGIPKV 1137
Query: 253 LIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGVGHAFQGPTARQELNTISSAPPQDHV 312
++VITDG+ D + + + + G +AIGV A EL +I S P HV
Sbjct: 1138 IVVITDGRSQDD---VNKISREMQLDGYSIFAIGVADA-----DYSELVSIGSKPSARHV 1189
Query: 313 FKVDNFAALGSIQKQL 328
F VD+F A I+ +L
Sbjct: 1190 FFVDDFDAFKKIEDEL 1205
Score = 68.2 bits (165), Expect = 4e-11
Identities = 56/207 (27%), Positives = 93/207 (44%), Gaps = 16/207 (7%)
Query: 150 DIVFLIDGSGSIDQNDFNQMKGFVQAVMGQFE--GTDTLFALMQYSNLLKIHFTFTQFRT 207
DIV L+DGS SI + +F ++ F++ ++ F+ T L QYS +I + F T
Sbjct: 158 DIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEWHLNAFST 217
Query: 208 SPSQQSLVDPIVQLKGLTFTATGILTVVTQLFHHKNGARKSAKKILIVITDGQKYKDPLE 267
V + G T T + + F + G+R KI I+ITDG+
Sbjct: 218 KDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILITDGK------S 271
Query: 268 YSDVIPQA---EKAGIIRYAIGVGHAFQGPTARQELNTISSAPPQDHVFKVDNFAALGSI 324
D+IP + ++G+ +AIGV +A EL I+S P HV+ V F + ++
Sbjct: 272 QDDIIPPSRNLRESGVELFAIGVKNA-----DVNELQEIASEPDSTHVYNVAEFDLMHTV 326
Query: 325 QKQLQEKIYAVEGTQSRASSSFQHEMS 351
+ L + + Q R + H ++
Sbjct: 327 VESLTRTLCSRVEEQDREIKASAHAIT 353
>gi|11321565 matrilin 3 precursor [Homo sapiens]
Length = 486
Score = 85.1 bits (209), Expect = 3e-16
Identities = 54/198 (27%), Positives = 100/198 (50%), Gaps = 13/198 (6%)
Query: 144 CPHQEMDIVFLIDGSGSIDQNDFNQMKGFVQAVMGQFE--GTDTLFALMQYSNLLKIHFT 201
C + +D+VF+ID S S+ +F ++K FV ++ + DT A++ Y++ +KI F
Sbjct: 77 CKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQ 136
Query: 202 FTQFRTSPSQQSLVDPIVQLKGLTFTATGILTVVTQLFHHKNGARKSAK---KILIVITD 258
+ S + V I L T + I T + + F + GAR+ + K+ I++TD
Sbjct: 137 LQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTD 196
Query: 259 GQKYKDPLEYSDVIPQAEKAGIIRYAIGVGHAFQGPTARQELNTISSAPPQDHVFKVDNF 318
G+ + ++V +A+ +GI YA+GV A L ++S P ++HVF V+ +
Sbjct: 197 GRPQD---QVNEVAARAQASGIELYAVGVDRADMA-----SLKMMASEPLEEHVFYVETY 248
Query: 319 AALGSIQKQLQEKIYAVE 336
+ + + QE A++
Sbjct: 249 GVIEKLSSRFQETFCALD 266
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,380,294
Number of Sequences: 37866
Number of extensions: 1948810
Number of successful extensions: 4370
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 3906
Number of HSP's gapped (non-prelim): 186
length of query: 1161
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1048
effective length of database: 13,968,660
effective search space: 14639155680
effective search space used: 14639155680
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.