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Search of human proteins with 61676184
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61676184 gonadotropin-releasing hormone receptor isoform 2
[Homo sapiens]
(249 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61676184 gonadotropin-releasing hormone receptor isoform 2 [H... 505 e-143
gi|4504059 gonadotropin-releasing hormone receptor isoform 1 [Ho... 343 6e-95
gi|4502331 arginine vasopressin receptor 1A [Homo sapiens] 83 2e-16
gi|4502333 arginine vasopressin receptor 1B [Homo sapiens] 79 3e-15
gi|32307152 oxytocin receptor [Homo sapiens] 75 4e-14
gi|222080109 orexin receptor 2 [Homo sapiens] 65 4e-11
gi|46395496 G protein-coupled receptor for asthma susceptibility... 65 7e-11
gi|46391085 G protein-coupled receptor for asthma susceptibility... 65 7e-11
gi|4503907 galanin receptor 3 [Homo sapiens] 64 1e-10
gi|4503905 galanin receptor 2 [Homo sapiens] 62 4e-10
gi|4502455 bombesin-like receptor 3 [Homo sapiens] 59 3e-09
gi|21426829 prokineticin receptor 2 [Homo sapiens] 59 4e-09
gi|222080095 orexin receptor 1 [Homo sapiens] 58 7e-09
gi|4885057 apelin receptor [Homo sapiens] 58 9e-09
gi|4885361 gastrin-releasing peptide receptor [Homo sapiens] 57 2e-08
gi|239757761 PREDICTED: similar to gastrin-releasing peptide rec... 57 2e-08
gi|31083315 G protein-coupled receptor 45 [Homo sapiens] 57 2e-08
gi|20373179 G protein-coupled receptor 73 [Homo sapiens] 56 3e-08
gi|4757888 complement component 3a receptor 1 [Homo sapiens] 55 4e-08
gi|4502819 cholinergic receptor, muscarinic 3 [Homo sapiens] 55 7e-08
gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sap... 54 2e-07
gi|225903385 arginine vasopressin receptor 2 isoform 2 [Homo sap... 54 2e-07
gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo sapiens] 54 2e-07
gi|157364957 pancreatic polypeptide receptor 1 [Homo sapiens] 53 3e-07
gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens] 52 4e-07
gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens] 52 5e-07
gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens] 52 5e-07
gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens] 52 5e-07
gi|23592220 G protein-coupled receptor 26 [Homo sapiens] 52 6e-07
gi|167000885 galanin receptor 1 [Homo sapiens] 52 6e-07
>gi|61676184 gonadotropin-releasing hormone receptor isoform 2 [Homo
sapiens]
Length = 249
Score = 505 bits (1300), Expect = e-143
Identities = 249/249 (100%), Positives = 249/249 (100%)
Query: 1 MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKL 60
MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKL
Sbjct: 1 MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKL 60
Query: 61 QKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYL 120
QKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYL
Sbjct: 61 QKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYL 120
Query: 121 KLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLPLHHP 180
KLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLPLHHP
Sbjct: 121 KLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLPLHHP 180
Query: 181 SFHHADLQCKNHLHPDTGPSSGPPRTTTESVQEQYTKSTAEDSKNDGCICHFIYCLLDSL 240
SFHHADLQCKNHLHPDTGPSSGPPRTTTESVQEQYTKSTAEDSKNDGCICHFIYCLLDSL
Sbjct: 181 SFHHADLQCKNHLHPDTGPSSGPPRTTTESVQEQYTKSTAEDSKNDGCICHFIYCLLDSL 240
Query: 241 LCPRNLVLV 249
LCPRNLVLV
Sbjct: 241 LCPRNLVLV 249
>gi|4504059 gonadotropin-releasing hormone receptor isoform 1 [Homo
sapiens]
Length = 328
Score = 343 bits (881), Expect = 6e-95
Identities = 175/175 (100%), Positives = 175/175 (100%)
Query: 1 MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKL 60
MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKL
Sbjct: 1 MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKL 60
Query: 61 QKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYL 120
QKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYL
Sbjct: 61 QKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYL 120
Query: 121 KLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQL 175
KLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQL
Sbjct: 121 KLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQL 175
>gi|4502331 arginine vasopressin receptor 1A [Homo sapiens]
Length = 418
Score = 83.2 bits (204), Expect = 2e-16
Identities = 46/140 (32%), Positives = 81/140 (57%), Gaps = 7/140 (5%)
Query: 36 KIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVM 95
K+ + V F ++ N+S LL L + +K SRM L ++HL+LA+L +
Sbjct: 52 KLEIAVLAVTFAVAVLGNSSVLLALHRTP------RKTSRMHLFIRHLSLADLAVAFFQV 105
Query: 96 PLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPL-ALKSNSK 154
W+IT ++ + LC+V+ +L++F M+A A+M+VV++ DR +A+ PL L+ ++
Sbjct: 106 LPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPAR 165
Query: 155 VGQSMVGLAWILSSVFAGPQ 174
+ M+ AW+LS V + PQ
Sbjct: 166 RSRLMIAAAWVLSFVLSTPQ 185
>gi|4502333 arginine vasopressin receptor 1B [Homo sapiens]
Length = 424
Score = 79.3 bits (194), Expect = 3e-15
Identities = 46/143 (32%), Positives = 83/143 (58%), Gaps = 11/143 (7%)
Query: 36 KIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVM 95
K+ + V + +L+ N + LL L + G+K SRM L + HL L +L L +
Sbjct: 35 KVEIGVLATVLVLATGGNLAVLLTLG------QLGRKRSRMHLFVLHLALTDLAVALFQV 88
Query: 96 PLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKV 155
+W+IT ++ +LLC+ + YL++ SM+A +M++ ++LDR LA+ P L+S +
Sbjct: 89 LPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHP--LRSLQQP 146
Query: 156 GQS---MVGLAWILSSVFAGPQL 175
GQS ++ W+L+++F+ PQ+
Sbjct: 147 GQSTYLLIAAPWLLAAIFSLPQV 169
>gi|32307152 oxytocin receptor [Homo sapiens]
Length = 389
Score = 75.5 bits (184), Expect = 4e-14
Identities = 43/140 (30%), Positives = 80/140 (57%), Gaps = 7/140 (5%)
Query: 36 KIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVM 95
++ V V + LL+ + NA LL L+ QK SR+ +KHL++A+L+ + +
Sbjct: 40 RVEVAVLCLILLLALSGNACVLLALRTTRQKH------SRLFFFMKHLSIADLVVAVFQV 93
Query: 96 PLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKV 155
+W+IT ++Y +LLC+++ YL++ M+A ++++++SLDR LAI +PL +
Sbjct: 94 LPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLR-SLRRRT 152
Query: 156 GQSMVGLAWILSSVFAGPQL 175
+ V W+ V + PQ+
Sbjct: 153 DRLAVLATWLGCLVASAPQV 172
>gi|222080109 orexin receptor 2 [Homo sapiens]
Length = 444
Score = 65.5 bits (158), Expect = 4e-11
Identities = 33/93 (35%), Positives = 55/93 (59%)
Query: 82 HLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSL 141
+L+LA++L T+ +P + +IT W+ G+ LCKV+ YL+ S+ + I+LDR
Sbjct: 95 NLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWY 154
Query: 142 AITRPLALKSNSKVGQSMVGLAWILSSVFAGPQ 174
AI PL KS +K ++ + + WI+S + PQ
Sbjct: 155 AICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQ 187
>gi|46395496 G protein-coupled receptor for asthma susceptibility
isoform A [Homo sapiens]
Length = 371
Score = 64.7 bits (156), Expect = 7e-11
Identities = 35/120 (29%), Positives = 65/120 (54%), Gaps = 1/120 (0%)
Query: 71 KKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAF 130
KK SRM + L + + L+ + D W T + A +L+C+V+ YL++ +YA +
Sbjct: 78 KKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTY 137
Query: 131 MMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLPLH-HPSFHHADLQC 189
++V +S+DR AI P+ K + ++ +AW LS +F+ P L + + + ++QC
Sbjct: 138 VLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTLIIFGKRTLSNGEVQC 197
>gi|46391085 G protein-coupled receptor for asthma susceptibility
isoform B [Homo sapiens]
Length = 377
Score = 64.7 bits (156), Expect = 7e-11
Identities = 35/120 (29%), Positives = 65/120 (54%), Gaps = 1/120 (0%)
Query: 71 KKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAF 130
KK SRM + L + + L+ + D W T + A +L+C+V+ YL++ +YA +
Sbjct: 78 KKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTY 137
Query: 131 MMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLPLH-HPSFHHADLQC 189
++V +S+DR AI P+ K + ++ +AW LS +F+ P L + + + ++QC
Sbjct: 138 VLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTLIIFGKRTLSNGEVQC 197
>gi|4503907 galanin receptor 3 [Homo sapiens]
Length = 368
Score = 63.9 bits (154), Expect = 1e-10
Identities = 40/143 (27%), Positives = 67/143 (46%), Gaps = 2/143 (1%)
Query: 35 GKIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIV 94
G + V V F L L T +L + + S L + +L +A+L L
Sbjct: 16 GAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCC 75
Query: 95 MPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKS--N 152
+P W G L+CK + L +MYA +F + +S+DR LA+ PL ++
Sbjct: 76 VPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRT 135
Query: 153 SKVGQSMVGLAWILSSVFAGPQL 175
+ ++ VGL W+L+++F+ P L
Sbjct: 136 PRNARAAVGLVWLLAALFSAPYL 158
>gi|4503905 galanin receptor 2 [Homo sapiens]
Length = 387
Score = 62.4 bits (150), Expect = 4e-10
Identities = 37/114 (32%), Positives = 58/114 (50%), Gaps = 2/114 (1%)
Query: 70 GKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPA 129
G+ +S L + +L +A+L L +P W G LLCK + +L +M+A +
Sbjct: 54 GQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASS 113
Query: 130 FMMVVISLDRSLAITRPLALKS--NSKVGQSMVGLAWILSSVFAGPQLPLHHPS 181
F + +SLDR LAI PL + + + +GL W LS +F+GP L + S
Sbjct: 114 FTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQS 167
>gi|4502455 bombesin-like receptor 3 [Homo sapiens]
Length = 399
Score = 59.3 bits (142), Expect = 3e-09
Identities = 30/99 (30%), Positives = 55/99 (55%), Gaps = 2/99 (2%)
Query: 78 LLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISL 137
+ + L +LL L +P+D + W G + CKVLS+++L S+ F + ++S
Sbjct: 84 IFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGRIGCKVLSFIRLTSVGVSVFTLTILSA 143
Query: 138 DRSLAITRPLALKSNSKVGQSMV--GLAWILSSVFAGPQ 174
DR A+ +PL + ++ + ++ V G WI+S +FA P+
Sbjct: 144 DRYKAVVKPLERQPSNAILKTCVKAGCVWIVSMIFALPE 182
>gi|21426829 prokineticin receptor 2 [Homo sapiens]
Length = 384
Score = 58.9 bits (141), Expect = 4e-09
Identities = 32/106 (30%), Positives = 58/106 (54%), Gaps = 3/106 (2%)
Query: 71 KKLSRM-KLLLKHLTLANLLETLIVMPLDGMWNITVQ--WYAGELLCKVLSYLKLFSMYA 127
KKL + LL+ +L +++ L +I P + + + Q W G +LC ++YL+ S+Y
Sbjct: 82 KKLRNLTNLLIANLAISDFLVAIICCPFEMDYYVVRQLSWEHGHVLCASVNYLRTVSLYV 141
Query: 128 PAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGP 173
++ I++DR LAI PL + N + ++ L W++S + A P
Sbjct: 142 STNALLAIAIDRYLAIVHPLKPRMNYQTASFLIALVWMVSILIAIP 187
>gi|222080095 orexin receptor 1 [Homo sapiens]
Length = 425
Score = 58.2 bits (139), Expect = 7e-09
Identities = 32/93 (34%), Positives = 49/93 (52%)
Query: 82 HLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSL 141
+L+LA++L T I +P + +IT W G LCKV+ YL+ S+ + I+LDR
Sbjct: 87 NLSLADVLVTAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWY 146
Query: 142 AITRPLALKSNSKVGQSMVGLAWILSSVFAGPQ 174
AI PL KS ++ + + W +S PQ
Sbjct: 147 AICHPLLFKSTARRARGSILGIWAVSLAIMVPQ 179
>gi|4885057 apelin receptor [Homo sapiens]
Length = 380
Score = 57.8 bits (138), Expect = 9e-09
Identities = 43/150 (28%), Positives = 70/150 (46%), Gaps = 15/150 (10%)
Query: 34 SGKIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLI 93
SG + + +FLL T N L WT + +K + + L +A+L ++
Sbjct: 27 SGALIPAIYMLVFLLGTTGNGLVL-----WTVFRSSREKRRSADIFIASLAVADLT-FVV 80
Query: 94 VMPLDGMWNIT-VQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSN 152
+PL + W G CK+ SYL +MYA F + +S DR LAI RP+A N
Sbjct: 81 TLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVA---N 137
Query: 153 SKV-----GQSMVGLAWILSSVFAGPQLPL 177
+++ G + W+L+++ A P + L
Sbjct: 138 ARLRLRVSGAVATAVLWVLAALLAMPVMVL 167
>gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]
Length = 384
Score = 56.6 bits (135), Expect = 2e-08
Identities = 35/131 (26%), Positives = 63/131 (48%), Gaps = 13/131 (9%)
Query: 78 LLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISL 137
L + L L +LL + P+D + +W G + CK++ +++L S+ F + +S
Sbjct: 77 LFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSA 136
Query: 138 DRSLAITRPLALKSNSKVGQSMVGLA--WILSSVFAGPQL------PLHHPSFHHADLQC 189
DR AI RP+ ++++ + + + A WI+S + A P+ P H S + + C
Sbjct: 137 DRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSDLHPFHEESTNQTFISC 196
Query: 190 -----KNHLHP 195
N LHP
Sbjct: 197 APYPHSNELHP 207
>gi|239757761 PREDICTED: similar to gastrin-releasing peptide
receptor [Homo sapiens]
Length = 368
Score = 56.6 bits (135), Expect = 2e-08
Identities = 35/131 (26%), Positives = 63/131 (48%), Gaps = 13/131 (9%)
Query: 78 LLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISL 137
L + L L +LL + P+D + +W G + CK++ +++L S+ F + +S
Sbjct: 61 LFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSA 120
Query: 138 DRSLAITRPLALKSNSKVGQSMVGLA--WILSSVFAGPQL------PLHHPSFHHADLQC 189
DR AI RP+ ++++ + + + A WI+S + A P+ P H S + + C
Sbjct: 121 DRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSDLHPFHEESTNQTFISC 180
Query: 190 -----KNHLHP 195
N LHP
Sbjct: 181 APYPHSNELHP 191
>gi|31083315 G protein-coupled receptor 45 [Homo sapiens]
Length = 372
Score = 56.6 bits (135), Expect = 2e-08
Identities = 31/102 (30%), Positives = 58/102 (56%), Gaps = 1/102 (0%)
Query: 74 SRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMV 133
S + LLL L ++++ +L MP + ITV+W+ G+ C++ + L F + +++
Sbjct: 67 SAINLLLATLAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILL 126
Query: 134 VISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQL 175
+IS+DR L I + K N + + ++ ++W+LS AGP L
Sbjct: 127 IISVDRFLIIVQRQD-KLNPRRAKVIIAVSWVLSFCIAGPSL 167
>gi|20373179 G protein-coupled receptor 73 [Homo sapiens]
Length = 393
Score = 56.2 bits (134), Expect = 3e-08
Identities = 30/106 (28%), Positives = 56/106 (52%), Gaps = 3/106 (2%)
Query: 71 KKLSRM-KLLLKHLTLANLLETLIVMPLDGMWNITVQ--WYAGELLCKVLSYLKLFSMYA 127
KKL + LL+ +L +++ L ++ P + + + Q W G +LC ++YL+ S+Y
Sbjct: 91 KKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHVLCTSVNYLRTVSLYV 150
Query: 128 PAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGP 173
++ I++DR LAI PL + + ++ L W +S + A P
Sbjct: 151 STNALLAIAIDRYLAIVHPLRPRMKCQTATGLIALVWTVSILIAIP 196
>gi|4757888 complement component 3a receptor 1 [Homo sapiens]
Length = 482
Score = 55.5 bits (132), Expect = 4e-08
Identities = 47/163 (28%), Positives = 77/163 (47%), Gaps = 15/163 (9%)
Query: 15 SAINNSIPLMQG--NLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKK 72
SA NS L+ N P + LS + + FLL N L W + +
Sbjct: 5 SAETNSTDLLSQPWNEPPVILS----MVILSLTFLLGLPGNGLVL-----WVAGLKMQRT 55
Query: 73 LSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMM 132
++ + L HLTLA+LL L + + QW G LCK++ + + +M+A F++
Sbjct: 56 VNTIWFL--HLTLADLLCCLSLPFSLAHLALQGQWPYGRFLCKLIPSIIVLNMFASVFLL 113
Query: 133 VVISLDRSLAITRPLALKSNSKVGQ--SMVGLAWILSSVFAGP 173
ISLDR L + +P+ +++ VG S+ G W+++ V P
Sbjct: 114 TAISLDRCLVVFKPIWCQNHRNVGMACSICGCIWVVAFVMCIP 156
>gi|4502819 cholinergic receptor, muscarinic 3 [Homo sapiens]
Length = 590
Score = 54.7 bits (130), Expect = 7e-08
Identities = 46/157 (29%), Positives = 67/157 (42%), Gaps = 25/157 (15%)
Query: 21 IPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLL 80
I + G L +T+ G I V V+F + T N FLL L
Sbjct: 71 IAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSL-------------------- 110
Query: 81 KHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRS 140
A+L+ +I M L + I +W G L C + + + A ++VIS DR
Sbjct: 111 ---ACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRY 167
Query: 141 LAITRPLA--LKSNSKVGQSMVGLAWILSSVFAGPQL 175
+ITRPL K +K M+GLAW++S V P +
Sbjct: 168 FSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAI 204
>gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo
sapiens]
Length = 390
Score = 53.5 bits (127), Expect = 2e-07
Identities = 42/166 (25%), Positives = 78/166 (46%), Gaps = 16/166 (9%)
Query: 4 SASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKLQKW 63
S++P QN CSA + +++L K+ + + L L+ T + +F++
Sbjct: 26 SSAPSQN---CSAKDYIYQ------DSISLPWKVLLVMLLALITLATTLSNAFVIATVYR 76
Query: 64 TQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLF 123
T+K + L+ L + +LL +++VMP+ M+ +T +W G+++C +
Sbjct: 77 TRKLH-----TPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDIT 131
Query: 124 SMYAPAFMMVVISLDRSLAITRPL--ALKSNSKVGQSMVGLAWILS 167
A + VI+LDR AIT + + K K M+ L W+ S
Sbjct: 132 CCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFS 177
>gi|225903385 arginine vasopressin receptor 2 isoform 2 [Homo
sapiens]
Length = 309
Score = 53.5 bits (127), Expect = 2e-07
Identities = 43/136 (31%), Positives = 70/136 (51%), Gaps = 6/136 (4%)
Query: 45 LFLLSATFNASFL---LKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMW 101
L LLS F A L L L ++ +G + + + + HL LA+L L + W
Sbjct: 41 LALLSIVFVAVALSNGLVLAALARRGRRGH-WAPIHVFIGHLCLADLAVALFQVLPQLAW 99
Query: 102 NITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRP-LALKSNSKVGQSM- 159
T ++ + LC+ + YL++ MYA ++M++ ++LDR AI RP LA + S +
Sbjct: 100 KATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRP 159
Query: 160 VGLAWILSSVFAGPQL 175
V +AW S + + PQL
Sbjct: 160 VLVAWAFSLLLSLPQL 175
>gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo sapiens]
Length = 371
Score = 53.5 bits (127), Expect = 2e-07
Identities = 43/136 (31%), Positives = 70/136 (51%), Gaps = 6/136 (4%)
Query: 45 LFLLSATFNASFL---LKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMW 101
L LLS F A L L L ++ +G + + + + HL LA+L L + W
Sbjct: 41 LALLSIVFVAVALSNGLVLAALARRGRRGH-WAPIHVFIGHLCLADLAVALFQVLPQLAW 99
Query: 102 NITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRP-LALKSNSKVGQSM- 159
T ++ + LC+ + YL++ MYA ++M++ ++LDR AI RP LA + S +
Sbjct: 100 KATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRP 159
Query: 160 VGLAWILSSVFAGPQL 175
V +AW S + + PQL
Sbjct: 160 VLVAWAFSLLLSLPQL 175
>gi|157364957 pancreatic polypeptide receptor 1 [Homo sapiens]
Length = 375
Score = 52.8 bits (125), Expect = 3e-07
Identities = 27/105 (25%), Positives = 53/105 (50%)
Query: 71 KKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAF 130
+K + LL+ +L ++ L L+ PL ++ I W GE LCK+ ++++ S+
Sbjct: 71 EKANVTNLLIANLAFSDFLMCLLCQPLTAVYTIMDYWIFGETLCKMSAFIQCMSVTVSIL 130
Query: 131 MMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQL 175
+V+++L+R I P K + + L W+++ V + P L
Sbjct: 131 SLVLVALERHQLIINPTGWKPSISQAYLGIVLIWVIACVLSLPFL 175
>gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens]
Length = 381
Score = 52.4 bits (124), Expect = 4e-07
Identities = 25/94 (26%), Positives = 50/94 (53%)
Query: 80 LKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDR 139
+ +L +A+LL + +P + + +W G +LC ++ Y + ++ + VI+LDR
Sbjct: 89 IANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDR 148
Query: 140 SLAITRPLALKSNSKVGQSMVGLAWILSSVFAGP 173
I L K + ++ ++GLAW +S++ A P
Sbjct: 149 HRCIVYHLESKISKRISFLIIGLAWGISALLASP 182
>gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens]
Length = 420
Score = 52.0 bits (123), Expect = 5e-07
Identities = 29/121 (23%), Positives = 55/121 (45%), Gaps = 3/121 (2%)
Query: 78 LLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISL 137
L + +L +++LL + MP+ + NI W G +CK+ ++ S+ A F +V I++
Sbjct: 82 LFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAV 141
Query: 138 DRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLPLHH---PSFHHADLQCKNHLH 194
DR + P K K ++ + W+L+ P + H ++ L +N
Sbjct: 142 DRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTS 201
Query: 195 P 195
P
Sbjct: 202 P 202
>gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens]
Length = 522
Score = 52.0 bits (123), Expect = 5e-07
Identities = 29/121 (23%), Positives = 55/121 (45%), Gaps = 3/121 (2%)
Query: 78 LLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISL 137
L + +L +++LL + MP+ + NI W G +CK+ ++ S+ A F +V I++
Sbjct: 184 LFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAV 243
Query: 138 DRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLPLHH---PSFHHADLQCKNHLH 194
DR + P K K ++ + W+L+ P + H ++ L +N
Sbjct: 244 DRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTS 303
Query: 195 P 195
P
Sbjct: 304 P 304
>gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens]
Length = 423
Score = 52.0 bits (123), Expect = 5e-07
Identities = 29/121 (23%), Positives = 55/121 (45%), Gaps = 3/121 (2%)
Query: 78 LLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISL 137
L + +L +++LL + MP+ + NI W G +CK+ ++ S+ A F +V I++
Sbjct: 85 LFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAV 144
Query: 138 DRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLPLHH---PSFHHADLQCKNHLH 194
DR + P K K ++ + W+L+ P + H ++ L +N
Sbjct: 145 DRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTS 204
Query: 195 P 195
P
Sbjct: 205 P 205
>gi|23592220 G protein-coupled receptor 26 [Homo sapiens]
Length = 337
Score = 51.6 bits (122), Expect = 6e-07
Identities = 32/114 (28%), Positives = 54/114 (47%), Gaps = 2/114 (1%)
Query: 78 LLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISL 137
L +LT NLL T++ MPL + + AG+ LC++ ++L F M +S+
Sbjct: 43 LFTLNLTCGNLLCTVVNMPLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSI 102
Query: 138 DRSLAITRPLALKSNSKVGQS--MVGLAWILSSVFAGPQLPLHHPSFHHADLQC 189
DR +A+ PL+ ++ ++ + MV W+ + F L L FH C
Sbjct: 103 DRWVAVVFPLSYRAKMRLRDAALMVAYTWLHALTFPAAALALSWLGFHQLYASC 156
>gi|167000885 galanin receptor 1 [Homo sapiens]
Length = 349
Score = 51.6 bits (122), Expect = 6e-07
Identities = 35/123 (28%), Positives = 54/123 (43%), Gaps = 9/123 (7%)
Query: 66 KKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSM 125
+ + GK S L + +L++A+L L +P W G +CK + Y SM
Sbjct: 60 RSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSM 119
Query: 126 YAPAFMMVVISLDRSLAI-----TRPLALKSNSKVGQSMVGLAWILSSVFAGPQLPLHHP 180
F + +S+DR +AI + L + N+ +G VG W LS A P + H
Sbjct: 120 LVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLG---VGCIWALSIAMASP-VAYHQG 175
Query: 181 SFH 183
FH
Sbjct: 176 LFH 178
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.134 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,687,507
Number of Sequences: 37866
Number of extensions: 407959
Number of successful extensions: 1765
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 263
Number of HSP's successfully gapped in prelim test: 71
Number of HSP's that attempted gapping in prelim test: 1447
Number of HSP's gapped (non-prelim): 355
length of query: 249
length of database: 18,247,518
effective HSP length: 100
effective length of query: 149
effective length of database: 14,460,918
effective search space: 2154676782
effective search space used: 2154676782
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.