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Search of human proteins with 5902090
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5902090 solute carrier family 2 (facilitated glucose
transporter), member 3 [Homo sapiens]
(496 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5902090 solute carrier family 2 (facilitated glucose transpor... 975 0.0
gi|23592238 glucose transporter 14 [Homo sapiens] 924 0.0
gi|166795299 solute carrier family 2 (facilitated glucose transp... 635 0.0
gi|4507011 glucose transporter 4 [Homo sapiens] 559 e-159
gi|4557851 solute carrier family 2 (facilitated glucose transpor... 501 e-142
gi|134053883 intestinal facilitative glucose transporter 7 [Homo... 366 e-101
gi|4507013 solute carrier family 2 (facilitated glucose/fructose... 363 e-100
gi|47933389 solute carrier family 2, member 9 protein isoform 2 ... 323 2e-88
gi|47933387 solute carrier family 2, member 9 protein isoform 1 ... 323 2e-88
gi|190684655 glucose transporter protein 10 isoform a [Homo sapi... 292 5e-79
gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens] 292 5e-79
gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens] 292 5e-79
gi|21361449 solute carrier family 2 (facilitated glucose transpo... 211 2e-54
gi|203098995 solute carrier family 2 (facilitated glucose transp... 169 7e-42
gi|207447703 solute carrier family 2 (facilitated glucose/fructo... 150 3e-36
gi|223029432 solute carrier family 2 (facilitated glucose transp... 137 2e-32
gi|223029430 solute carrier family 2 (facilitated glucose transp... 136 5e-32
gi|21553331 solute carrier family 2 (facilitated glucose transpo... 129 6e-30
gi|13540547 solute carrier family 2 member 10 [Homo sapiens] 101 2e-21
gi|4507005 solute carrier family 22 member 5 [Homo sapiens] 72 1e-12
gi|24497490 solute carrier family 22 member 4 [Homo sapiens] 66 6e-11
gi|8923870 solute carrier family 22 member 11 [Homo sapiens] 53 7e-07
gi|11415038 solute carrier family 22 member 3 [Homo sapiens] 53 7e-07
gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens] 51 2e-06
gi|4507001 solute carrier family 22 member 2 [Homo sapiens] 50 6e-06
gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens] 49 1e-05
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap... 47 3e-05
gi|213021148 SVOP-like isoform 1 [Homo sapiens] 47 3e-05
gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa... 47 4e-05
gi|216548223 synaptic vesicle glycoprotein 2 [Homo sapiens] 45 2e-04
>gi|5902090 solute carrier family 2 (facilitated glucose
transporter), member 3 [Homo sapiens]
Length = 496
Score = 975 bits (2520), Expect = 0.0
Identities = 496/496 (100%), Positives = 496/496 (100%)
Query: 1 MGTQKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLT 60
MGTQKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLT
Sbjct: 1 MGTQKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLT 60
Query: 61 SLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEML 120
SLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEML
Sbjct: 61 SLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEML 120
Query: 121 ILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGS 180
ILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGS
Sbjct: 121 ILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGS 180
Query: 181 EELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQ 240
EELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQ
Sbjct: 181 EELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQ 240
Query: 241 EMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAG 300
EMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAG
Sbjct: 241 EMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAG 300
Query: 301 VQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYN 360
VQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYN
Sbjct: 301 VQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYN 360
Query: 361 GMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLF 420
GMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLF
Sbjct: 361 GMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLF 420
Query: 421 PSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGV 480
PSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGV
Sbjct: 421 PSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGV 480
Query: 481 MEMNSIEPAKETTTNV 496
MEMNSIEPAKETTTNV
Sbjct: 481 MEMNSIEPAKETTTNV 496
>gi|23592238 glucose transporter 14 [Homo sapiens]
Length = 520
Score = 924 bits (2388), Expect = 0.0
Identities = 469/494 (94%), Positives = 482/494 (97%)
Query: 3 TQKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSL 62
T VTPALIFAITVATIGSFQFGYNTGVINAPE IIKEFINKTLTDK NAPPSEVLLT+L
Sbjct: 27 TLAVTPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNL 86
Query: 63 WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLIL 122
WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLA TGGC MGLCK+A+SVEMLIL
Sbjct: 87 WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLIL 146
Query: 123 GRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEE 182
GRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIV+GILVAQIFGLE ILGSEE
Sbjct: 147 GRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEE 206
Query: 183 LWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEM 242
LWP+LLGFTILPAILQSAALP CPESPRFLLINRK+EENA +ILQRLWGTQDVSQDIQEM
Sbjct: 207 LWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEM 266
Query: 243 KDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ 302
KDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ
Sbjct: 267 KDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ 326
Query: 303 EPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGM 362
+PIYATI AGVVNTIFT++SLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLK++YNGM
Sbjct: 327 QPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGM 386
Query: 363 SFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPS 422
SFVCIGAILVFVA FEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPS
Sbjct: 387 SFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPS 446
Query: 423 AAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGVME 482
AA+YLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGVM
Sbjct: 447 AAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGVMG 506
Query: 483 MNSIEPAKETTTNV 496
MNSIEPAKETTTNV
Sbjct: 507 MNSIEPAKETTTNV 520
>gi|166795299 solute carrier family 2 (facilitated glucose
transporter), member 1 [Homo sapiens]
Length = 492
Score = 635 bits (1639), Expect = 0.0
Identities = 314/477 (65%), Positives = 386/477 (80%), Gaps = 1/477 (0%)
Query: 3 TQKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSL 62
++K+T L+ A+ A +GS QFGYNTGVINAP+K+I+EF N+T + LT+L
Sbjct: 5 SKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTL 64
Query: 63 WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLIL 122
WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSML++NLLA MG K+ KS EMLIL
Sbjct: 65 WSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLIL 124
Query: 123 GRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEE 182
GR +IG++CGL TGFVPMY+GE+SPTALRGA GTL+QLGIVVGIL+AQ+FGL+ I+G+++
Sbjct: 125 GRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKD 184
Query: 183 LWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEM 242
LWPLLL +PA+LQ LPFCPESPRFLLINR EE AK +L++L GT DV+ D+QEM
Sbjct: 185 LWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEM 244
Query: 243 KDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ 302
K+ES +M +EK+VT+LELFR +YRQPI+I++VLQLSQQLSGINAVFYYST IF+ AGVQ
Sbjct: 245 KEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQ 304
Query: 303 EPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGM 362
+P+YATIG+G+VNT FTVVSLF+VERAGRRTLH+IGL GMA C+ LMT++L L + M
Sbjct: 305 QPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQLPWM 364
Query: 363 SFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPS 422
S++ I AI FVAFFE+GPGPIPWFIVAELFSQGPRPAA+AVAG SNWTSNF+VG+ F
Sbjct: 365 SYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQY 424
Query: 423 AAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF-EGQAHGADRSGKD 478
G YVFIIFT L+ F FT+FKVPET+GRTF++I F +G A +D++ ++
Sbjct: 425 VEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPEE 481
>gi|4507011 glucose transporter 4 [Homo sapiens]
Length = 509
Score = 559 bits (1440), Expect = e-159
Identities = 284/466 (60%), Positives = 356/466 (76%), Gaps = 4/466 (0%)
Query: 4 QKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKT-LTDKGNAPPSEV---LL 59
Q+VT L+ A+ A +GS QFGYN GVINAP+K+I++ N+T L +G PS + L
Sbjct: 18 QRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTL 77
Query: 60 TSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEM 119
T+LW+LSVAIFSVGGMI SF +G+ GR+ +ML+ N+LAV GG MGL A S EM
Sbjct: 78 TTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEM 137
Query: 120 LILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILG 179
LILGR +IG + GL +G VPMY+GEI+PT LRGA GTLNQL IV+GIL+AQ+ GLE +LG
Sbjct: 138 LILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLG 197
Query: 180 SEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDI 239
+ LWPLLLG T+LPA+LQ LPFCPESPR+L I + E A++ L+RL G DVS +
Sbjct: 198 TASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSGVL 257
Query: 240 QEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDA 299
E+KDE ++ +E+ +++L+L ++RQP+II++VLQLSQQLSGINAVFYYST IF+ A
Sbjct: 258 AELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETA 317
Query: 300 GVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNY 359
GV +P YATIGAGVVNT+FT+VS+ LVERAGRRTLH++GL GM C+ LMTV+LLL +
Sbjct: 318 GVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAILMTVALLLLERV 377
Query: 360 NGMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLL 419
MS+V I AI FVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAG SNWTSNF++G+
Sbjct: 378 PAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMG 437
Query: 420 FPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 465
F A +G YVF++F L+ F FTF +VPETRGRTF+ I+ AF
Sbjct: 438 FQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAF 483
>gi|4557851 solute carrier family 2 (facilitated glucose
transporter), member 2 [Homo sapiens]
Length = 524
Score = 501 bits (1289), Expect = e-142
Identities = 257/508 (50%), Positives = 346/508 (68%), Gaps = 34/508 (6%)
Query: 1 MGTQKVTPALIFAITVATIGSFQFGYNTGVINAPEKII--------------KEFINK-- 44
M KVT L+F + A +GSFQFGY+ GVINAP+++I ++ IN
Sbjct: 1 MTEDKVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYV 60
Query: 45 --------TLTDKGNAPPSE----------VLLTSLWSLSVAIFSVGGMIGSFSVGLFVN 86
T++ N P+ L+T LWSLSV+ F+VGGM SF G +
Sbjct: 61 INSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGD 120
Query: 87 RFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEIS 146
GR +ML+ N+L++ G MG K+ S ++I GR + GL+CGL +G VPMYIGEI+
Sbjct: 121 TLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIA 180
Query: 147 PTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCP 206
PTALRGA GT +QL IV GIL++QI GLEFILG+ +LW +LLG + + AILQS L FCP
Sbjct: 181 PTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCP 240
Query: 207 ESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSY 266
ESPR+L I EE AKQ L+RL G DV++DI EM+ E S E++V++++LF SSY
Sbjct: 241 ESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSY 300
Query: 267 RQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIYATIGAGVVNTIFTVVSLFLV 326
RQPI+++++L ++QQ SGIN +FYYST IF+ AG+ +P+YATIG G VN +FT VS+FLV
Sbjct: 301 RQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLV 360
Query: 327 ERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVCIGAILVFVAFFEIGPGPIPW 386
E+AGRR+L +IG+ GM C+ M+V L+L + ++ MS+V + AI +FV+FFEIGPGPIPW
Sbjct: 361 EKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPW 420
Query: 387 FIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFT 446
F+VAE FSQGPRPAA+A+A SNWT NF+V L F A + G YVF +F G L+ F FT
Sbjct: 421 FMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFT 480
Query: 447 FFKVPETRGRTFEDITRAFEGQAHGADR 474
FFKVPET+G++FE+I F+ ++ A R
Sbjct: 481 FFKVPETKGKSFEEIAAEFQKKSGSAHR 508
>gi|134053883 intestinal facilitative glucose transporter 7 [Homo
sapiens]
Length = 512
Score = 366 bits (939), Expect = e-101
Identities = 193/494 (39%), Positives = 297/494 (60%), Gaps = 5/494 (1%)
Query: 5 KVTPALIFAITVATIGS-FQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLW 63
++ P L+ A A GS FQ+GYN V+N P K+ K F N+T ++ L+ LW
Sbjct: 18 RLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLMLLLW 77
Query: 64 SLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILG 123
S +V++F +GG++GS VGL V+ GR+ ++LI N+ A+ MG+ KVAK+ E+++
Sbjct: 78 SCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFS 137
Query: 124 RLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEEL 183
R+V+G+ G+ +PMY+GE++P LRG GT+ ++ ++VG+ +AQIF L+ ILG+
Sbjct: 138 RVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAG 197
Query: 184 WPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMK 243
WP+LL T +PA+LQ LPF PESPR+ LI + +E A+Q L+RL G D+ ++++M+
Sbjct: 198 WPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMR 257
Query: 244 DESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ- 302
E+ E ++VL L + S R ++ IVL QQLSGINA+ YY+ I+ AGV+
Sbjct: 258 AEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGVEA 317
Query: 303 -EPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNG 361
Y T+G+GVVN + T+ S LVER GRR L + G G ++TV LL ++
Sbjct: 318 AHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRVPE 377
Query: 362 MSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFP 421
+S++ I + ++A IGP P+P + E+F Q R AA V G +W +NF++G LFP
Sbjct: 378 LSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFP 437
Query: 422 SAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGVM 481
S +GAY FIIF G + + + +PET+G+TF +I R F + K+ +
Sbjct: 438 SIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRNRVKLPEEKEETI 497
Query: 482 EMN--SIEPAKETT 493
+ + PAKET+
Sbjct: 498 DAGPPTASPAKETS 511
>gi|4507013 solute carrier family 2 (facilitated glucose/fructose
transporter), member 5 isoform 1 [Homo sapiens]
Length = 501
Score = 363 bits (933), Expect = e-100
Identities = 190/464 (40%), Positives = 282/464 (60%), Gaps = 3/464 (0%)
Query: 5 KVTPALIFAITVATIGS-FQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLW 63
++T L A +A GS FQ+GYN +N+P ++++F N+T + + LT LW
Sbjct: 12 RLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLW 71
Query: 64 SLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILG 123
S++V++F GG IGS VG VN+FGR+ ++L N+ ++ MG +VA S E++I+
Sbjct: 72 SVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIIS 131
Query: 124 RLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEEL 183
RL++G+ G+ + VPMY+GE++P LRGA G + QL I VGILVAQIFGL +L + +
Sbjct: 132 RLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDG 191
Query: 184 WPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMK 243
WP+LLG T +PA LQ LPF PESPR+LLI +K+E AK+ LQ L G V +++ E++
Sbjct: 192 WPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIR 251
Query: 244 DESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQE 303
E ++VL+LFR+ S R ++ IVL QQLSG+NA++YY+ I+ AGV E
Sbjct: 252 QEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPE 311
Query: 304 P--IYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNG 361
Y T G G VN + T ++F+VE GRR L ++G ++T +L L+D +
Sbjct: 312 EHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVSW 371
Query: 362 MSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFP 421
M ++ I ++ +V +GP PIP ++ E+F Q RP+A V G +W SNF VGL+FP
Sbjct: 372 MPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFP 431
Query: 422 SAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 465
LG Y FI+F + + F VPET+ +TF +I + F
Sbjct: 432 FIQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIF 475
>gi|47933389 solute carrier family 2, member 9 protein isoform 2
[Homo sapiens]
Length = 511
Score = 323 bits (829), Expect = 2e-88
Identities = 170/458 (37%), Positives = 262/458 (57%), Gaps = 2/458 (0%)
Query: 10 LIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVAI 69
L+ ++ A SF +GYN V+NAP IK F N++ + P LT LWS++V+I
Sbjct: 28 LVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVSI 87
Query: 70 FSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGL 129
F++GG++G+ V + GR++++L N A++ M A + EMLI+GR ++G+
Sbjct: 88 FAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGI 147
Query: 130 FCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLG 189
G+ +PMY+ EISP +RG+ G + + I +G+ Q+ GL +LG E WP L G
Sbjct: 148 DGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFG 207
Query: 190 FTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARM 249
++PA++Q +LPF P+SPR+LL+ + E A + Q G DVSQ+++E+ ES
Sbjct: 208 VIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQ 267
Query: 250 SQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV--QEPIYA 307
+ V+VLEL R R ++ IV QL G+NA+++Y+ IF AG+ + Y
Sbjct: 268 RSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYV 327
Query: 308 TIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVCI 367
T+ G + T+ V S ++E GRR L + G G M +T++L L+D+ + ++ I
Sbjct: 328 TLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLSI 387
Query: 368 GAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYL 427
IL +A F GPG IP+ + E F Q RPAA +AG NW SNF VGLLFP L
Sbjct: 388 VGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSL 447
Query: 428 GAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 465
Y F++F IT + +F +PET+ RT+ +I++AF
Sbjct: 448 DTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAF 485
>gi|47933387 solute carrier family 2, member 9 protein isoform 1
[Homo sapiens]
Length = 540
Score = 323 bits (829), Expect = 2e-88
Identities = 170/458 (37%), Positives = 262/458 (57%), Gaps = 2/458 (0%)
Query: 10 LIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVAI 69
L+ ++ A SF +GYN V+NAP IK F N++ + P LT LWS++V+I
Sbjct: 57 LVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVSI 116
Query: 70 FSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGL 129
F++GG++G+ V + GR++++L N A++ M A + EMLI+GR ++G+
Sbjct: 117 FAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGI 176
Query: 130 FCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLG 189
G+ +PMY+ EISP +RG+ G + + I +G+ Q+ GL +LG E WP L G
Sbjct: 177 DGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFG 236
Query: 190 FTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARM 249
++PA++Q +LPF P+SPR+LL+ + E A + Q G DVSQ+++E+ ES
Sbjct: 237 VIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQ 296
Query: 250 SQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV--QEPIYA 307
+ V+VLEL R R ++ IV QL G+NA+++Y+ IF AG+ + Y
Sbjct: 297 RSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYV 356
Query: 308 TIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVCI 367
T+ G + T+ V S ++E GRR L + G G M +T++L L+D+ + ++ I
Sbjct: 357 TLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLSI 416
Query: 368 GAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYL 427
IL +A F GPG IP+ + E F Q RPAA +AG NW SNF VGLLFP L
Sbjct: 417 VGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSL 476
Query: 428 GAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 465
Y F++F IT + +F +PET+ RT+ +I++AF
Sbjct: 477 DTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAF 514
>gi|190684655 glucose transporter protein 10 isoform a [Homo
sapiens]
Length = 503
Score = 292 bits (747), Expect = 5e-79
Identities = 161/457 (35%), Positives = 258/457 (56%), Gaps = 3/457 (0%)
Query: 10 LIFAITVATIG-SFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVA 68
L+ I A IG +FQFGYN +INAP I+EF N+T + P + L+ +WSL V+
Sbjct: 20 LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 79
Query: 69 IFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIG 128
++ +GG+ G+ G GR+ S+L+ N+ V+ G + A S EM++LGRL++G
Sbjct: 80 LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 139
Query: 129 LFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLL 188
+ G+ PMY+GE +P LRGA + + +GI++ Q+ GL +LG + WPLLL
Sbjct: 140 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 199
Query: 189 GFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESAR 248
++P LQ A+LP PESPR+LLI+ + E L+RL G+ D++ +++E+++E A
Sbjct: 200 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 259
Query: 249 MSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEP--IY 306
+ ELF+ + R+ + +VL + +L G ++V+ Y++ +F+ AGV E Y
Sbjct: 260 CQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQY 319
Query: 307 ATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVC 366
A IG G + VVS ++ER GRR L + G M ++ TV+L L+ ++ ++
Sbjct: 320 AIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLA 379
Query: 367 IGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHY 426
+ I F+ F IGP + + ELF Q RPAA V G W LVGL FP
Sbjct: 380 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEA 439
Query: 427 LGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITR 463
L ++++ F G + +T +PET+G+TF++I++
Sbjct: 440 LSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISK 476
>gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]
Length = 496
Score = 292 bits (747), Expect = 5e-79
Identities = 161/457 (35%), Positives = 258/457 (56%), Gaps = 3/457 (0%)
Query: 10 LIFAITVATIG-SFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVA 68
L+ I A IG +FQFGYN +INAP I+EF N+T + P + L+ +WSL V+
Sbjct: 13 LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 72
Query: 69 IFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIG 128
++ +GG+ G+ G GR+ S+L+ N+ V+ G + A S EM++LGRL++G
Sbjct: 73 LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 132
Query: 129 LFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLL 188
+ G+ PMY+GE +P LRGA + + +GI++ Q+ GL +LG + WPLLL
Sbjct: 133 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 192
Query: 189 GFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESAR 248
++P LQ A+LP PESPR+LLI+ + E L+RL G+ D++ +++E+++E A
Sbjct: 193 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 252
Query: 249 MSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEP--IY 306
+ ELF+ + R+ + +VL + +L G ++V+ Y++ +F+ AGV E Y
Sbjct: 253 CQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQY 312
Query: 307 ATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVC 366
A IG G + VVS ++ER GRR L + G M ++ TV+L L+ ++ ++
Sbjct: 313 AIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLA 372
Query: 367 IGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHY 426
+ I F+ F IGP + + ELF Q RPAA V G W LVGL FP
Sbjct: 373 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEA 432
Query: 427 LGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITR 463
L ++++ F G + +T +PET+G+TF++I++
Sbjct: 433 LSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISK 469
>gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]
Length = 499
Score = 292 bits (747), Expect = 5e-79
Identities = 161/457 (35%), Positives = 258/457 (56%), Gaps = 3/457 (0%)
Query: 10 LIFAITVATIG-SFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVA 68
L+ I A IG +FQFGYN +INAP I+EF N+T + P + L+ +WSL V+
Sbjct: 16 LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 75
Query: 69 IFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIG 128
++ +GG+ G+ G GR+ S+L+ N+ V+ G + A S EM++LGRL++G
Sbjct: 76 LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 135
Query: 129 LFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLL 188
+ G+ PMY+GE +P LRGA + + +GI++ Q+ GL +LG + WPLLL
Sbjct: 136 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 195
Query: 189 GFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESAR 248
++P LQ A+LP PESPR+LLI+ + E L+RL G+ D++ +++E+++E A
Sbjct: 196 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 255
Query: 249 MSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEP--IY 306
+ ELF+ + R+ + +VL + +L G ++V+ Y++ +F+ AGV E Y
Sbjct: 256 CQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQY 315
Query: 307 ATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVC 366
A IG G + VVS ++ER GRR L + G M ++ TV+L L+ ++ ++
Sbjct: 316 AIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLA 375
Query: 367 IGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHY 426
+ I F+ F IGP + + ELF Q RPAA V G W LVGL FP
Sbjct: 376 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEA 435
Query: 427 LGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITR 463
L ++++ F G + +T +PET+G+TF++I++
Sbjct: 436 LSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISK 472
>gi|21361449 solute carrier family 2 (facilitated glucose
transporter), member 8 [Homo sapiens]
Length = 477
Score = 211 bits (536), Expect = 2e-54
Identities = 151/481 (31%), Positives = 241/481 (50%), Gaps = 51/481 (10%)
Query: 10 LIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVAI 69
+ A A +G FG+ G + ++ APP+ L + S A+
Sbjct: 26 VFLAAFAAALGPLSFGFALGYSSPAIPSLQRA----------APPAPRLDDAAASWFGAV 75
Query: 70 FSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGL 129
++G G G V+R GR+ S+L+ ++ V G + A+ V ML+ GRL+ GL
Sbjct: 76 VTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAG---FAVITAAQDVWMLLGGRLLTGL 132
Query: 130 FCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLG 189
CG+ + P+YI EI+ A+RG G+ QL +VVGIL+A + G ++L E W +LG
Sbjct: 133 ACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAG--WVL--EWRWLAVLG 188
Query: 190 FTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARM 249
+P L + F PE+PRFLL + +E A L+ LWG++ +D ++S +
Sbjct: 189 --CVPPSLMLLLMCFMPETPRFLLTQHRRQE-AMAALRFLWGSEQGWEDPPIGAEQSFHL 245
Query: 250 SQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIYATI 309
+ L R +P II + L QQLSG+NAV +Y+ IF++A ++ A++
Sbjct: 246 A---------LLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASV 296
Query: 310 GAGVVNTIFTVVSLFLVERAGRRTLHMI---------------------GLGGMAFCSTL 348
GV+ +FT V+ +++RAGRR L ++ G G + +
Sbjct: 297 VVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAIS 356
Query: 349 MTVSLLLKDNYNGMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCS 408
VS D G++++ +G++ +F+A F +G GPIPW +++E+F + A + +
Sbjct: 357 APVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLT 416
Query: 409 NWTSNFLVGLLFPSAAHYLGAY-VFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEG 467
NW FLV F S L Y F + + F I + FT F VPET+G+T E IT FEG
Sbjct: 417 NWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEG 476
Query: 468 Q 468
+
Sbjct: 477 R 477
>gi|203098995 solute carrier family 2 (facilitated glucose
transporter), member 13 [Homo sapiens]
Length = 648
Score = 169 bits (427), Expect = 7e-42
Identities = 115/360 (31%), Positives = 184/360 (51%), Gaps = 27/360 (7%)
Query: 4 QKVTPALIFAITV-ATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSL 62
Q TPA ++ + V + +G F FGY+TGV++ ++K ++ L +L
Sbjct: 74 QDETPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKR---------------QLSLDAL 118
Query: 63 WSLSVAIFSVGGMIGSFSVGLFVNR-FGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLI 121
W + +VG S G +N FGRR ++L+ + L G + A + E L+
Sbjct: 119 WQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLA---AANNKETLL 175
Query: 122 LGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSE 181
GRLV+GL G+ + VP+YI E+SP LRG T+N L I G A + F +
Sbjct: 176 AGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQK 235
Query: 182 ELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQE 241
+ W +LG +PA++Q F PESPR+ LI + + + A++IL ++ G Q + ++
Sbjct: 236 DGWRYMLGLAAVPAVIQFFGFLFLPESPRW-LIQKGQTQKARRILSQMRGNQTIDEEYDS 294
Query: 242 MKDESARMSQEKQVTVLELFRVSSY---RQPIIISIVLQLSQQLSGINAVFYYSTGIFKD 298
+K+ +E + R+ SY R+ +I+ LQ+ QQLSGIN + YYS I +
Sbjct: 295 IKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQM 354
Query: 299 AGVQEPIYATIGAGV---VNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLL 355
+GV++ A A V N IFT+V ++LVE+ GRR L L G ++ + +L
Sbjct: 355 SGVEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVL 414
Score = 68.6 bits (166), Expect = 1e-11
Identities = 36/117 (30%), Positives = 58/117 (49%), Gaps = 1/117 (0%)
Query: 363 SFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPS 422
S+ + +++++ FF G GP+PW + +E++ R A + NW N LV L F
Sbjct: 506 SWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLH 565
Query: 423 AAHYLGAY-VFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKD 478
A YL Y F ++ GF L F + +PET+G+ E+I F+ + S D
Sbjct: 566 TAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNRLCTCGTSDSD 622
>gi|207447703 solute carrier family 2 (facilitated glucose/fructose
transporter), member 5 isoform 2 [Homo sapiens]
Length = 244
Score = 150 bits (378), Expect = 3e-36
Identities = 75/177 (42%), Positives = 114/177 (64%), Gaps = 1/177 (0%)
Query: 5 KVTPALIFAITVATIGS-FQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLW 63
++T L A +A GS FQ+GYN +N+P ++++F N+T + + LT LW
Sbjct: 12 RLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLW 71
Query: 64 SLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILG 123
S++V++F GG IGS VG VN+FGR+ ++L N+ ++ MG +VA S E++I+
Sbjct: 72 SVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIIS 131
Query: 124 RLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGS 180
RL++G+ G+ + VPMY+GE++P LRGA G + QL I VGILVAQIFGL +L +
Sbjct: 132 RLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLAN 188
>gi|223029432 solute carrier family 2 (facilitated glucose
transporter), member 6 isoform 1 [Homo sapiens]
Length = 507
Score = 137 bits (345), Expect = 2e-32
Identities = 131/490 (26%), Positives = 212/490 (43%), Gaps = 63/490 (12%)
Query: 10 LIFAITVATIGSFQFGY----NTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSL 65
+ A A +G+F FGY + VI A E+ + P L S S
Sbjct: 38 VFLATFAAVLGNFSFGYALVYTSPVIPALERSLD--------------PDLHLTKSQASW 83
Query: 66 SVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRL 125
++F++G G S + + GR+ S++ + + G M A + ML+LGR
Sbjct: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMA---GAHGLWMLLLGRT 140
Query: 126 VIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWP 185
+ G GL +P+Y+ EI+P +RGA G QL V G L ++ L +L W
Sbjct: 141 LTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSL--SLYALGLLLP----WR 194
Query: 186 LLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQ-DVSQDIQEMKD 244
L P ++ L F P SPRFLL +R +E A + L L GT DV + ++++D
Sbjct: 195 WLAVAGEAPVLIMILLLSFMPNSPRFLL-SRGRDEEALRALAWLRGTDVDVHWEFEQIQD 253
Query: 245 ESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEP 304
R Q +V+ E R +PI ++++++L QQL+GI + Y IF V P
Sbjct: 254 NVRR--QSSRVSWAEA-RAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLP 310
Query: 305 IYATIG-AGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLL-------LK 356
G V + +++ ++ AGR+ L + + F + L T+ L L
Sbjct: 311 PKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVS-AAIMFAANL-TLGLYIHFGPRPLS 368
Query: 357 DNYNG--------------------MSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQG 396
N ++ V + A ++F+ + +G GPI W +++E+
Sbjct: 369 PNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLR 428
Query: 397 PRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYV-FIIFTGFLITFLAFTFFKVPETRG 455
R A + ++W + F++ F G V F F + L FT VPET+G
Sbjct: 429 ARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKG 488
Query: 456 RTFEDITRAF 465
R+ E I F
Sbjct: 489 RSLEQIESFF 498
>gi|223029430 solute carrier family 2 (facilitated glucose
transporter), member 6 isoform 2 [Homo sapiens]
Length = 445
Score = 136 bits (342), Expect = 5e-32
Identities = 124/463 (26%), Positives = 198/463 (42%), Gaps = 71/463 (15%)
Query: 10 LIFAITVATIGSFQFGY----NTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSL 65
+ A A +G+F FGY + VI A E+ + P L S S
Sbjct: 38 VFLATFAAVLGNFSFGYALVYTSPVIPALERSLD--------------PDLHLTKSQASW 83
Query: 66 SVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRL 125
++F++G G S + + GR+ S++ + + G M A + ML+LGR
Sbjct: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMA---GAHGLWMLLLGRT 140
Query: 126 VIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWP 185
+ G GL +P+Y+ EI+P +RGA G QL V G L ++ L +L W
Sbjct: 141 LTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSL--SLYALGLLLP----WR 194
Query: 186 LLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQ-DVSQDIQEMKD 244
L P ++ L F P SPRFLL +R +E A + L L GT DV + ++++D
Sbjct: 195 WLAVAGEAPVLIMILLLSFMPNSPRFLL-SRGRDEEALRALAWLRGTDVDVHWEFEQIQD 253
Query: 245 ESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEP 304
R Q +V+ E R +PI ++++++L QQL+GI + Y IF V P
Sbjct: 254 NVRR--QSSRVSWAEA-RAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLP 310
Query: 305 IYATIG-AGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMS 363
G V + +++ ++ AGR+
Sbjct: 311 PKDDAAIVGAVRLLSVLIAALTMDLAGRK------------------------------- 339
Query: 364 FVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSA 423
+L+FV+ + +G GPI W +++E+ R A + ++W + F++ F
Sbjct: 340 ------VLLFVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPV 393
Query: 424 AHYLGAYV-FIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 465
G V F F + L FT VPET+GR+ E I F
Sbjct: 394 VSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFF 436
>gi|21553331 solute carrier family 2 (facilitated glucose
transporter), member 12 [Homo sapiens]
Length = 617
Score = 129 bits (324), Expect = 6e-30
Identities = 99/354 (27%), Positives = 179/354 (50%), Gaps = 28/354 (7%)
Query: 17 ATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMI 76
A + GY G+I+ IK + + ++ E++++SL +G ++
Sbjct: 47 AAVSGLLVGYELGIISGALLQIKTLLALSCHEQ------EMVVSSL--------VIGALL 92
Query: 77 GSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTG 136
S + G+ ++R+GRR ++++ + L G + L + S +LI+GR+ IG+ L +
Sbjct: 93 ASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLIL---SLSYTVLIVGRIAIGVSISLSSI 149
Query: 137 FVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAI 196
+YI EI+P RG +LN+L IV+GIL A I F W + G I +
Sbjct: 150 ATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAF-ANVFHGWKYMFGLVIPLGV 208
Query: 197 LQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQVT 256
LQ+ A+ F P SPRFL++ + +E A ++L RL D ++++ +K + + E Q +
Sbjct: 209 LQAIAMYFLPPSPRFLVM-KGQEGAASKVLGRLRALSDTTEELTVIK---SSLKDEYQYS 264
Query: 257 VLELFR-VSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQE---PIYATIGAG 312
+LFR + R I+I + L Q++G + +Y++ + K G Q A+ G G
Sbjct: 265 FWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVG 324
Query: 313 VVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVC 366
VV I T+ + LV+ G +T IG MA ++L+T+ ++ + + + +C
Sbjct: 325 VVKVISTIPATLLVDHVGSKTFLCIGSSVMA--ASLVTMGIVNLNIHMNFTHIC 376
Score = 73.6 bits (179), Expect = 4e-13
Identities = 36/102 (35%), Positives = 59/102 (57%), Gaps = 1/102 (0%)
Query: 362 MSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFP 421
+ ++ + ++LV+VA F IG GP+PW +++E+F G R AMA+ NW N L+ L F
Sbjct: 460 LKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFL 519
Query: 422 SAAHYLG-AYVFIIFTGFLITFLAFTFFKVPETRGRTFEDIT 462
+ +G +V I+T + L F +PET+G + E I+
Sbjct: 520 TVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQIS 561
>gi|13540547 solute carrier family 2 member 10 [Homo sapiens]
Length = 541
Score = 101 bits (251), Expect = 2e-21
Identities = 93/342 (27%), Positives = 156/342 (45%), Gaps = 45/342 (13%)
Query: 8 PALIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSV 67
P L +V+ +G FGY VI+ ++ + ++ E L+ SL
Sbjct: 6 PVLPLCASVSLLGGLTFGYELAVISGALLPLQLDFGLSCLEQ------EFLVGSLL---- 55
Query: 68 AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVI 127
+G ++ S G ++ +GR+ ++L NL+ + G +GL A S+ L+LGR V+
Sbjct: 56 ----LGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGL---AGSLAWLVLGRAVV 108
Query: 128 GLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFIL-GSEELWPL 186
G L + +Y+ E+ RG +L + GI VGIL++ + L + L G+ W
Sbjct: 109 GFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLS--YALNYALAGTPWGWRH 166
Query: 187 LLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDES 246
+ G+ PA+LQS +L F P E K ++ G E+
Sbjct: 167 MFGWATAPAVLQSLSLLFLPAGT-------DETATHKDLIPLQGG-------------EA 206
Query: 247 ARMSQEK-QVTVLELFRV-SSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ-- 302
++ + + + L+LFR + R + + L L QQL+G V Y++ IF G
Sbjct: 207 PKLGPGRPRYSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGG 266
Query: 303 -EPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMA 343
+ A++G G V T+ ++ LV+RAGRR L + G MA
Sbjct: 267 SSAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMA 308
Score = 60.1 bits (144), Expect = 5e-09
Identities = 28/98 (28%), Positives = 53/98 (54%), Gaps = 1/98 (1%)
Query: 370 ILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLG- 428
++VFV+ F G GP+ W +++E++ R A A NW +N + L F +G
Sbjct: 416 LMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGL 475
Query: 429 AYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFE 466
++ F+++ + L F + VPET+G++ +I + F+
Sbjct: 476 SWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQ 513
>gi|4507005 solute carrier family 22 member 5 [Homo sapiens]
Length = 557
Score = 72.0 bits (175), Expect = 1e-12
Identities = 110/417 (26%), Positives = 184/417 (44%), Gaps = 62/417 (14%)
Query: 65 LSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGR 124
L++++F VG ++GSF G +RFGR+N +L V + TG F+ + +K+ EM ++
Sbjct: 144 LTISLFFVGVLLGSFISGQLSDRFGRKN-VLFVTMGMQTGFSFLQI--FSKNFEMFVVLF 200
Query: 125 LVIGLFCGLCTGFVPMYI--GEISPTALRGAFGTLNQ-LGIVVGILVAQIFGLEFILGSE 181
+++G+ G + +V ++ EI ++R F TL + G +V +F FI
Sbjct: 201 VLVGM--GQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAFGYMVLPLFAY-FIRD-- 255
Query: 182 ELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQ---- 237
W +LL +P +L A F PESPR+L+ + EE A+ I+++ +
Sbjct: 256 --WRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEE-AEVIIRKAAKANGIVVPSTI 312
Query: 238 -DIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLS-------QQLSGINAVF 289
D E++D S++ Q +L+L R + R I+SI+L ++ L N
Sbjct: 313 FDPSELQDLSSKKQQSH--NILDLLRTWNIRMVTIMSIMLWMTISVGYFGLSLDTPNLHG 370
Query: 290 YYSTGIFKDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRR--TLHMIGLGGMAFCST 347
F A V+ P Y V++ L++ RR + LGG S
Sbjct: 371 DIFVNCFLSAMVEVPAY-------------VLAWLLLQYLPRRYSMATALFLGG----SV 413
Query: 348 LMTVSLLLKDNYNGMSFVCIGAILVFVAFFEIGPG-PIPWFIVAELFSQGPRPAAMAVAG 406
L+ + L+ D Y + +LV V F + + + AEL+ R + V+
Sbjct: 414 LLFMQLVPPDLY------YLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSS 467
Query: 407 CSNWTSNFLVGLLFPSAAHYLGAY---VFIIFTGFLITFLAFTFFKVPETRGRTFED 460
T++ L +L P YLGAY + I G L A +PE+ G D
Sbjct: 468 ----TASRLGSILSPYFV-YLGAYDRFLPYILMGSLTILTAILTLFLPESFGTPLPD 519
>gi|24497490 solute carrier family 22 member 4 [Homo sapiens]
Length = 551
Score = 66.2 bits (160), Expect = 6e-11
Identities = 105/409 (25%), Positives = 182/409 (44%), Gaps = 48/409 (11%)
Query: 65 LSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGR 124
L+ ++F VG ++GSF G +RFGR+N +L + TG F+ + + S EM +
Sbjct: 144 LTTSLFFVGVLLGSFVSGQLSDRFGRKN-VLFATMAVQTGFSFLQIFSI--SWEMFTVLF 200
Query: 125 LVIGLFCGLCTGFVPMYI--GEISPTALRGAFGTLNQLG-IVVGILVAQIFGLEFILGSE 181
+++G+ G + +V +I EI ++R F TL VG ++ +F FI
Sbjct: 201 VIVGM--GQISNYVVAFILGTEILGKSVRIIFSTLGVCTFFAVGYMLLPLFAY-FIRD-- 255
Query: 182 ELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQD--I 239
W +LL +P +L F PESPR+L+ R+ E A+ I+Q+ +++ I
Sbjct: 256 --WRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFRE-AEDIIQKAAKMNNIAVPAVI 312
Query: 240 QEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDA 299
+ +E + Q+K +L+LFR + I+S++L + + +V Y++ + DA
Sbjct: 313 FDSVEELNPLKQQK-AFILDLFRTRNIAIMTIMSLLLWM------LTSVGYFALSL--DA 363
Query: 300 -GVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGL---GGMAFCSTLMTVSLLL 355
+ Y + I ++ +L+ R R + + GG L+ + L+
Sbjct: 364 PNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYIIAAVLFWGG----GVLLFIQLVP 419
Query: 356 KDNYNGMSFVCIGAILVFVAFFEIGPG-PIPWFIVAELFSQGPRPAAMAVAGCSNWTSNF 414
D Y F+ IG LV + F I + + AEL+ R A+ V ++
Sbjct: 420 VDYY----FLSIG--LVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTAS----- 468
Query: 415 LVGLLFPSAAHYLGAY---VFIIFTGFLITFLAFTFFKVPETRGRTFED 460
VG + YLGAY + I G L + PE+ G T +
Sbjct: 469 RVGSIIAPYFVYLGAYNRMLPYIVMGSLTVLIGILTLFFPESLGMTLPE 517
>gi|8923870 solute carrier family 22 member 11 [Homo sapiens]
Length = 550
Score = 52.8 bits (125), Expect = 7e-07
Identities = 96/436 (22%), Positives = 167/436 (38%), Gaps = 47/436 (10%)
Query: 65 LSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNL-LAVTGGCFMGLCKVAKSVEMLILG 123
LS +IF G ++GSF GL RFGR+ + L LAV G + ++ G
Sbjct: 144 LSQSIFMSGILVGSFIWGLLSYRFGRKPMLSWCCLQLAVA-----GTSTIFAPTFVIYCG 198
Query: 124 RLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEEL 183
+ F G+ F+ + T T+ +G A + GL F L
Sbjct: 199 LRFVAAF-GMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSAGQAALGGLAFALRD--- 254
Query: 184 WPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQI--LQRLWGTQDVSQDIQE 241
W L +P S + PES R+L+I K ++ +++ + R+ G ++ E
Sbjct: 255 WRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVARINGHKEAKNLTIE 314
Query: 242 MKDESAR---MSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKD 298
+ S + S ++ +VL+LF V R +V+ S +S VF + + +D
Sbjct: 315 VLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLISYYGLVFDLQS-LGRD 373
Query: 299 AGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDN 358
+ + ++ G V+ + + L+ GRRT I G A + ++L+ +
Sbjct: 374 IFLLQALF-----GAVDFLGRATTALLLSFLGRRT---IQAGSQAMAGLAILANMLVPQD 425
Query: 359 YNGMSFV-------CIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWT 411
+ V C G L + ++ AELF P P M G +
Sbjct: 426 LQTLRVVFAVLGKGCFGISLTCLTIYK-----------AELF---PTPVRMTADGILHTV 471
Query: 412 SNF--LVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQA 469
++G L + L +++ I F +PET+G D + E Q
Sbjct: 472 GRLGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLESQK 531
Query: 470 HGADRSGKDGVMEMNS 485
A + + + + S
Sbjct: 532 STAAQGNRQEAVTVES 547
>gi|11415038 solute carrier family 22 member 3 [Homo sapiens]
Length = 556
Score = 52.8 bits (125), Expect = 7e-07
Identities = 92/419 (21%), Positives = 184/419 (43%), Gaps = 40/419 (9%)
Query: 56 EVLLTSLWSLSV--AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMG-LCK 112
+++ + W L + AI ++G + G+F++G +R+GR +++ LL+ G G +
Sbjct: 145 DLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADRYGR----IVIYLLSCLGVGVTGVVVA 200
Query: 113 VAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIF 172
A + + ++ R + G+F + + EI + R G + Q+ +GI++ +
Sbjct: 201 FAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIII--LP 258
Query: 173 GLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRL--W 230
G+ + + + W + LP+ L PESPR+ LI RK+ + A QIL+R+
Sbjct: 259 GIAYFIPN---WQGIQLAITLPSFLFLLYYWVVPESPRW-LITRKKGDKALQILRRIAKC 314
Query: 231 GTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFY 290
+ +S + E+ +S + L+L R R+ +I + + +
Sbjct: 315 NGKYLSSNYSEITVTDEEVSNP---SFLDLVRTPQMRKCTLILM-------FAWFTSAVV 364
Query: 291 YSTGIFKDAGVQEPIYATIG-AGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLM 349
Y + + + +Y +GVV ++ L +ER GRR L +A + L+
Sbjct: 365 YQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRR-LPFAASNIVAGVACLV 423
Query: 350 TVSLLLKDNYNGMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAV-AGCS 408
T L + + +G + + +AF I + + +EL+ R +++ +G
Sbjct: 424 TAFLPEGIAWLRTTVATLGRLGITMAF------EIVYLVNSELYPTTLRNFGVSLCSGLC 477
Query: 409 NWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRG----RTFEDITR 463
++ LLF AA +L + +I G L + +PET+G T +D+ +
Sbjct: 478 DFGGIIAPFLLFRLAAVWL--ELPLIIFGILASICGGLVMLLPETKGIALPETVDDVEK 534
>gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens]
Length = 727
Score = 51.2 bits (121), Expect = 2e-06
Identities = 56/209 (26%), Positives = 87/209 (41%), Gaps = 17/209 (8%)
Query: 68 AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVI 127
+I +G M+G+F G ++ GR+ S+LI + G F L + + RL+
Sbjct: 195 SIVYLGMMVGAFFWGGLADKVGRKQSLLICMSV---NGFFAFLSSFVQGYGFFLFCRLLS 251
Query: 128 GLFCGLCTGFVPMYIGEISPTALRGA-FGTLNQLGIVVGILVAQI-------FGLEFILG 179
G G V Y E+ RG L ++ GI + + +G F +G
Sbjct: 252 GFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMG 311
Query: 180 SE---ELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVS 236
S W + + LP + AL F PESPRFLL K +E A IL+ + T +
Sbjct: 312 SAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDE-AWMILKLIHDTNMRA 370
Query: 237 QDIQEMKDESARMSQEKQVTVLELFRVSS 265
+ E ++ KQ+ EL + S
Sbjct: 371 RGQPEKVFTVNKIKTPKQID--ELIEIES 397
>gi|4507001 solute carrier family 22 member 2 [Homo sapiens]
Length = 555
Score = 49.7 bits (117), Expect = 6e-06
Identities = 46/161 (28%), Positives = 72/161 (44%), Gaps = 13/161 (8%)
Query: 71 SVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLF 130
+VG IGS S+G +RFGR+ +L L+ G M ++ + +++ RL+ GL
Sbjct: 157 NVGFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMA---ISPTYTWMLIFRLIQGLV 213
Query: 131 --CGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLL 188
G G++ I E R G Q+ VG+LV + G+ + L W L
Sbjct: 214 SKAGWLIGYI--LITEFVGRRYRRTVGIFYQVAYTVGLLV--LAGVAYALPH---WRWLQ 266
Query: 189 GFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRL 229
LP PESPR+L+ K E A +I++ +
Sbjct: 267 FTVALPNFFFLLYYWCIPESPRWLISQNKNAE-AMRIIKHI 306
>gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens]
Length = 683
Score = 48.9 bits (115), Expect = 1e-05
Identities = 49/177 (27%), Positives = 75/177 (42%), Gaps = 19/177 (10%)
Query: 69 IFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIG 128
I +G M G+F +G ++ GR+ ++++ F L + + RL+ G
Sbjct: 153 IVYLGMMAGAFILGGLADKLGRKR---VLSMSLAVNASFASLSSFVQGYGAFLFCRLISG 209
Query: 129 LFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGI--VVGILVAQI--------FGLEFIL 178
+ G V Y E RG L+ LGI + G L A +G F +
Sbjct: 210 IGIGGALPIVFAYFSEFLSREKRGEH--LSWLGIFWMTGGLYASAMAWSIIPHYGWGFSM 267
Query: 179 GSE---ELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGT 232
G+ W + + LP + AL F PESPRFLL K +E A IL+++ T
Sbjct: 268 GTNYHFHSWRVFVIVCALPCTVSMVALKFMPESPRFLLEMGKHDE-AWMILKQVHDT 323
>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
sapiens]
Length = 554
Score = 47.4 bits (111), Expect = 3e-05
Identities = 93/439 (21%), Positives = 172/439 (39%), Gaps = 44/439 (10%)
Query: 63 WSLSV--AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEML 120
W L + + + G + GS VG F +RFGR+ +L L+ G M + + +
Sbjct: 146 WKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAF---SPNYMSM 202
Query: 121 ILGRLVIGLFC--GLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFIL 178
+L RL+ GL G+ I E + R + Q+ VG++ + GL + L
Sbjct: 203 LLFRLLQGLVSKGNWMAGYT--LITEFVGSGSRRTVAIMYQMAFTVGLVA--LTGLAYAL 258
Query: 179 GSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAK---QILQRLWGTQDV 235
W L LP L PESPR+LL ++ E K I Q+
Sbjct: 259 PH---WRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPA 315
Query: 236 SQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGI 295
+ ++++ ++++ + +LFR R+ I + L + ++V Y +
Sbjct: 316 DLKMLSLEED---VTEKLSPSFADLFRTPRLRKRTFILMYLWFT------DSVLYQGLIL 366
Query: 296 FKDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGR-RTLHMIGLGGMAFCSTLMTVSLL 354
A + + +V ++L ++R GR + M L A C ++ +S
Sbjct: 367 HMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFISPD 426
Query: 355 LKDNYNGMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNF 414
L ++ + +C+G + + +A I + AEL+ R + V CS+
Sbjct: 427 L--HWLNIIIMCVGRMGITIAIQMI------CLVNAELYPTFVRNLGVMV--CSSLCD-- 474
Query: 415 LVGLLFPSAAHYL----GAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAH 470
+ G++ P L A I+F + T +PET+G + + E
Sbjct: 475 IGGIITPFIVFRLREVWQALPLILFAVLGLLAAGVTLL-LPETKGVALPETMKDAENLGR 533
Query: 471 GADRSGKDGVMEMNSIEPA 489
A +++ + EP+
Sbjct: 534 KAKPKENTIYLKVQTSEPS 552
>gi|213021148 SVOP-like isoform 1 [Homo sapiens]
Length = 492
Score = 47.4 bits (111), Expect = 3e-05
Identities = 51/186 (27%), Positives = 80/186 (43%), Gaps = 14/186 (7%)
Query: 27 NTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVN 86
+TGV+ A E ++ ++ + + +V L + + G M+ S GL +
Sbjct: 56 STGVVEAMEIMLIAVVSPVIRCEWQLENWQVALVT------TMVFFGYMVFSILFGLLAD 109
Query: 87 RFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIG-EI 145
R+GR +LI L G F L A S + R ++G CG+ + I E
Sbjct: 110 RYGRWKILLISFLW---GAYFSLLTSFAPSYIWFVFLRTMVG--CGVSGHSQGLIIKTEF 164
Query: 146 SPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFC 205
PT RG L+Q+ + G L+ I GL ++ W L+ +P I+ A F
Sbjct: 165 LPTKYRGYMLPLSQVFWLAGSLL--IIGLASVIIPTIGWRWLIRVASIPGIILIVAFKFI 222
Query: 206 PESPRF 211
PES RF
Sbjct: 223 PESARF 228
Score = 32.3 bits (72), Expect = 1.0
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 13/105 (12%)
Query: 83 LFVNRFGRRNSMLIVNLLAVTGGC---FMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVP 139
L +N GRR S L++T GC F L + S LI ++ V
Sbjct: 363 LGINFLGRRLS------LSITMGCTALFFLLLNICTSSAGLIGFLFMLRALVAANFNTVY 416
Query: 140 MYIGEISPTALR----GAFGTLNQLGIVVGILVAQIFGLEFILGS 180
+Y E+ PT +R G G+L ++G +V ++Q+ ILG+
Sbjct: 417 IYTAEVYPTTMRALGMGTSGSLCRIGAMVAPFISQVLMSASILGA 461
>gi|23510410 solute carrier family 22 member 1 isoform b [Homo
sapiens]
Length = 506
Score = 47.0 bits (110), Expect = 4e-05
Identities = 70/321 (21%), Positives = 131/321 (40%), Gaps = 29/321 (9%)
Query: 63 WSLSV--AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEML 120
W L + + + G + GS VG F +RFGR+ +L L+ G M + + +
Sbjct: 146 WKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAF---SPNYMSM 202
Query: 121 ILGRLVIGLFC--GLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFIL 178
+L RL+ GL G+ I E + R + Q+ VG++ + GL + L
Sbjct: 203 LLFRLLQGLVSKGNWMAGYT--LITEFVGSGSRRTVAIMYQMAFTVGLVA--LTGLAYAL 258
Query: 179 GSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAK---QILQRLWGTQDV 235
W L LP L PESPR+LL ++ E K I Q+
Sbjct: 259 PH---WRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPA 315
Query: 236 SQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGI 295
+ ++++ ++++ + +LFR R+ I + L + ++V Y +
Sbjct: 316 DLKMLSLEED---VTEKLSPSFADLFRTPRLRKRTFILMYLWFT------DSVLYQGLIL 366
Query: 296 FKDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGR-RTLHMIGLGGMAFCSTLMTVSLL 354
A + + +V ++L ++R GR + M L A C ++ +S
Sbjct: 367 HMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFISPD 426
Query: 355 LKDNYNGMSFVCIGAILVFVA 375
L ++ + +C+G + + +A
Sbjct: 427 L--HWLNIIIMCVGRMGITIA 445
>gi|216548223 synaptic vesicle glycoprotein 2 [Homo sapiens]
Length = 742
Score = 45.1 bits (105), Expect = 2e-04
Identities = 48/175 (27%), Positives = 73/175 (41%), Gaps = 15/175 (8%)
Query: 69 IFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIG 128
I +G M+G+F G +R GRR +LI L+V F + + RL+ G
Sbjct: 210 IVYLGMMVGAFLWGGLADRLGRRQCLLIS--LSVNS-VFAFFSSFVQGYGTFLFCRLLSG 266
Query: 129 LFCGLCTGFVPMYIGEISPTALRGA-FGTLNQLGIVVGILVAQI-------FGLEFILGS 180
+ G V Y E RG L ++ G+ A + +G F +GS
Sbjct: 267 VGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAMAWAIIPHYGWSFQMGS 326
Query: 181 E---ELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGT 232
W + + P++ AL PESPRF L N K +E A +L+++ T
Sbjct: 327 AYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFLENGKHDE-AWMVLKQVHDT 380
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.141 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,027,583
Number of Sequences: 37866
Number of extensions: 723694
Number of successful extensions: 2441
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 2332
Number of HSP's gapped (non-prelim): 84
length of query: 496
length of database: 18,247,518
effective HSP length: 106
effective length of query: 390
effective length of database: 14,233,722
effective search space: 5551151580
effective search space used: 5551151580
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.