BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Homo sapiens] (486 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Ho... 943 0.0 gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Hom... 921 0.0 gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens] 796 0.0 gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Hom... 204 1e-52 gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Hom... 204 2e-52 gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Hom... 196 5e-50 gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Hom... 181 1e-45 gi|57863257 T-complex protein 1 isoform a [Homo sapiens] 181 1e-45 gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo ... 179 4e-45 gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo... 179 7e-45 gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens] 162 6e-40 gi|57863259 T-complex protein 1 isoform b [Homo sapiens] 142 9e-34 gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Hom... 133 4e-31 gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo ... 129 8e-30 gi|7657253 T-complex protein 1 [Homo sapiens] 86 1e-16 gi|41399285 chaperonin [Homo sapiens] 45 1e-04 gi|31542947 chaperonin [Homo sapiens] 45 1e-04 gi|21735548 centrosomal protein 2 [Homo sapiens] 36 0.069 gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 35 0.20 gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 34 0.34 gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 33 0.76 gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 33 0.76 gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 33 0.76 gi|70980531 GGA binding partner [Homo sapiens] 33 0.76 gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho... 32 0.99 gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho... 32 0.99 gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho... 32 0.99 gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho... 32 0.99 gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 32 0.99 gi|10863929 ribonuclease L [Homo sapiens] 32 1.3 >gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Homo sapiens] Length = 486 Score = 943 bits (2437), Expect = 0.0 Identities = 486/486 (100%), Positives = 486/486 (100%) Query: 1 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG 60 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG Sbjct: 1 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG 60 Query: 61 NVLLHEMGLHPRIITEGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELA 120 NVLLHEMGLHPRIITEGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELA Sbjct: 61 NVLLHEMGLHPRIITEGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELA 120 Query: 121 DVLTEAVVDSILAIKKQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRV 180 DVLTEAVVDSILAIKKQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRV Sbjct: 121 DVLTEAVVDSILAIKKQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRV 180 Query: 181 EDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDS 240 EDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDS Sbjct: 181 EDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDS 240 Query: 241 DKGFVVINQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLG 300 DKGFVVINQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLG Sbjct: 241 DKGFVVINQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLG 300 Query: 301 HAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDG 360 HAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDG Sbjct: 301 HAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDG 360 Query: 361 CVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVK 420 CVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVK Sbjct: 361 CVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVK 420 Query: 421 IQAEHSESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAG 480 IQAEHSESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAG Sbjct: 421 IQAEHSESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAG 480 Query: 481 MSSLKG 486 MSSLKG Sbjct: 481 MSSLKG 486 >gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Homo sapiens] Length = 531 Score = 921 bits (2381), Expect = 0.0 Identities = 486/531 (91%), Positives = 486/531 (91%), Gaps = 45/531 (8%) Query: 1 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG 60 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG Sbjct: 1 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG 60 Query: 61 NVLLHEM---------------------------------------------GLHPRIIT 75 NVLLHEM GLHPRIIT Sbjct: 61 NVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIIT 120 Query: 76 EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK 135 EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK Sbjct: 121 EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK 180 Query: 136 KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYE 195 KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYE Sbjct: 181 KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYE 240 Query: 196 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF 255 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF Sbjct: 241 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF 300 Query: 256 SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF 315 SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF Sbjct: 301 SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF 360 Query: 316 TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE 375 TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE Sbjct: 361 TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE 420 Query: 376 ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD 435 ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD Sbjct: 421 ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD 480 Query: 436 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG 486 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG Sbjct: 481 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG 531 >gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens] Length = 530 Score = 796 bits (2055), Expect = 0.0 Identities = 411/530 (77%), Positives = 455/530 (85%), Gaps = 45/530 (8%) Query: 1 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG 60 MAA+K +N KAEVARA+AALAVNI AARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG Sbjct: 1 MAAIKAVNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG 60 Query: 61 NVLLHEM---------------------------------------------GLHPRIIT 75 NVLL EM GLHPRII Sbjct: 61 NVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIA 120 Query: 76 EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK 135 EGFEAAK KAL+ LEEVKV++EM R+ L+DVARTSL+TKVHAELADVLTE VVDS+LA++ Sbjct: 121 EGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR 180 Query: 136 KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYE 195 + PIDLFM+EIMEMKHK TDT LI+GLVLDHGARHPDMKKRVEDA+IL CNVSLEYE Sbjct: 181 RPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYE 240 Query: 196 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF 255 KTEVNSGFFYK+AEE+EKLVKAERKFIEDRV+KII+LK KVC S+KGFVVINQKGIDPF Sbjct: 241 KTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPF 300 Query: 256 SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF 315 SLD+L+K GIVALRRAKRRNMERL+LACGG+A+NSF+DL+ DCLGHAGLVYEYTLGEEKF Sbjct: 301 SLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKF 360 Query: 316 TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE 375 TFIE+C NP SVTLL+KGPNKHTLTQ+KDA+RDGLRA+KNAI+DGC+VPGAGA+EVAMAE Sbjct: 361 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE 420 Query: 376 ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD 435 AL+ +K S+KGRA+LGVQAFADALLIIPKVLAQN+G+D QETLVK+QAEH ES QLVGVD Sbjct: 421 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVD 480 Query: 436 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK 485 LNTGEPMVAA+ GVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK Sbjct: 481 LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK 530 >gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Homo sapiens] Length = 544 Score = 204 bits (519), Expect = 1e-52 Identities = 132/506 (26%), Positives = 258/506 (50%), Gaps = 60/506 (11%) Query: 23 NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMG-------------- 68 NI+AA+ + D++RT LGPK MKML+ G I +T DGN +L E+ Sbjct: 26 NINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHPAAKSMIEISR 85 Query: 69 ------------------------------LHPRIITEGFEAAKEKALQFLEEVKVSREM 98 +HP ++ + A + + L+++ + ++ Sbjct: 86 TQDEEVGDGTTSVIILGEMLSVAEHFLEQQMHPTVVISAYRKALDDMISTLKKISIPVDI 145 Query: 99 -DRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQD---EPIDLFMIEIME-MKH 153 D + ++++ +S+ TK + + + +D++ ++ ++ + ID+ +E + Sbjct: 146 SDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEENGRKEIDIKKYARVEKIPG 205 Query: 154 KSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREK 213 D+ ++RG++++ HP M++ +++ I+ + SLEY+K E + E+ + Sbjct: 206 GIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTR 265 Query: 214 LVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAKR 273 +++ E ++I+ + II+LK V VI +KGI + L + I A+RR ++ Sbjct: 266 ILQMEEEYIQQLCEDIIQLKPDV---------VITEKGISDLAQHYLMRANITAIRRVRK 316 Query: 274 RNMERLTLACGGVALNSFDDLSPDCLGH-AGLVYEYTLGEEKFTFIEKCNNPRSVTLLIK 332 + R+ ACG ++ ++L D +G AGL+ +G+E FTFI C +P++ T+L++ Sbjct: 317 TDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLR 376 Query: 333 GPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGV 392 G +K L++++ ++D ++ +N + D +VPG GA E+A+A AL + ++ G Q Sbjct: 377 GASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPY 436 Query: 393 QAFADALLIIPKVLAQNSGFDLQETLVKIQAEHS-ESGQLVGVDLNTGEPMVAAEVGVWD 451 +A A AL +IP+ L QN G L ++A+H+ E+ + GV+ TG + E+G+W+ Sbjct: 437 RAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIWE 496 Query: 452 NYCVKKQLLHSCTVIATNILLVDEIM 477 VK Q + A +L +D+I+ Sbjct: 497 PLAVKLQTYKTAVETAVLLLRIDDIV 522 >gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Homo sapiens] Length = 545 Score = 204 bits (518), Expect = 2e-52 Identities = 132/507 (26%), Positives = 258/507 (50%), Gaps = 61/507 (12%) Query: 23 NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMG-------------- 68 NI+AA+ + D++RT LGPK MKML+ G I +T DGN +L E+ Sbjct: 26 NINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHPAAKSMIEISR 85 Query: 69 -------------------------------LHPRIITEGFEAAKEKALQFLEEVKVSRE 97 +HP ++ + A + + L+++ + + Sbjct: 86 TQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKALDDMISTLKKISIPVD 145 Query: 98 M-DRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQD---EPIDLFMIEIME-MK 152 + D + ++++ +S+ TK + + + +D++ ++ ++ + ID+ +E + Sbjct: 146 ISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEENGRKEIDIKKYARVEKIP 205 Query: 153 HKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEERE 212 D+ ++RG++++ HP M++ +++ I+ + SLEY+K E + E+ Sbjct: 206 GGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFT 265 Query: 213 KLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAK 272 ++++ E ++I+ + II+LK V VI +KGI + L + I A+RR + Sbjct: 266 RILQMEEEYIQQLCEDIIQLKPDV---------VITEKGISDLAQHYLMRANITAIRRVR 316 Query: 273 RRNMERLTLACGGVALNSFDDLSPDCLGH-AGLVYEYTLGEEKFTFIEKCNNPRSVTLLI 331 + + R+ ACG ++ ++L D +G AGL+ +G+E FTFI C +P++ T+L+ Sbjct: 317 KTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILL 376 Query: 332 KGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLG 391 +G +K L++++ ++D ++ +N + D +VPG GA E+A+A AL + ++ G Q Sbjct: 377 RGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWP 436 Query: 392 VQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHS-ESGQLVGVDLNTGEPMVAAEVGVW 450 +A A AL +IP+ L QN G L ++A+H+ E+ + GV+ TG + E+G+W Sbjct: 437 YRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIW 496 Query: 451 DNYCVKKQLLHSCTVIATNILLVDEIM 477 + VK Q + A +L +D+I+ Sbjct: 497 EPLAVKLQTYKTAVETAVLLLRIDDIV 523 >gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Homo sapiens] Length = 541 Score = 196 bits (497), Expect = 5e-50 Identities = 148/519 (28%), Positives = 248/519 (47%), Gaps = 67/519 (12%) Query: 19 ALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEM----------- 67 AL +I AA+ + + +RT+LGP G KM+V GD+ +T DG +L M Sbjct: 33 ALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKLMV 92 Query: 68 ----------------------------------GLHPRIITEGFEAAKEKALQFLEEVK 93 G+HP I +G+E A A++ L+++ Sbjct: 93 ELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKIS 152 Query: 94 VSREMD---RETLIDVARTSLRTKV----HAELADVLTEAVVDSILAIKKQDEPIDLFMI 146 S +D E LI A+T+L +KV H ++A++ AV+ ++ ++++D +D +I Sbjct: 153 DSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVL-TVADMERRD--VDFELI 209 Query: 147 EIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYK 206 ++ DT LI+G+++D HP M K+VEDA I E K + Sbjct: 210 KVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVT 269 Query: 207 SAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIV 266 S E+ + L K E++ E+ +++I E + I Q G D + L + + Sbjct: 270 SVEDYKALQKYEKEKFEEMIQQIKETGANLA---------ICQWGFDDEANHLLLQNNLP 320 Query: 267 ALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLG--EEKFTFIEKCNNP 324 A+R +E + +A GG + F +L+ + LG AGLV E + G ++K IE+C N Sbjct: 321 AVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNS 380 Query: 325 RSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSV 384 R+VT+ I+G NK + + K ++ D L ++N I D VV G GA E++ A A+ + Sbjct: 381 RAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKC 440 Query: 385 KGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEH-SESGQLVGVDLNTGEPMV 443 Q ++AFADAL +IP L++NSG + +T+ +++A E +G+D Sbjct: 441 PTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTND 500 Query: 444 AAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMS 482 + V + KKQ + T + IL +D+I + G S Sbjct: 501 MKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGES 539 >gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Homo sapiens] Length = 507 Score = 181 bits (460), Expect = 1e-45 Identities = 121/470 (25%), Positives = 250/470 (53%), Gaps = 24/470 (5%) Query: 18 AALAVNISAARGLQDVLRTN---LGPKGTMKMLVSGAGDIKLTKDGNVLLHEMGLHPRII 74 A + V AA+ + ++ RT +G T ++++G L+ + L E +HP ++ Sbjct: 30 AKIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGE---MLSVAEHFL--EQQMHPTVV 84 Query: 75 TEGFEAAKEKALQFLEEVKVSREM-DRETLIDVARTSLRTKVHAELADVLTEAVVDSILA 133 + A + + L+++ + ++ D + ++++ +S+ TK + + + +D++ Sbjct: 85 ISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKM 144 Query: 134 IKKQD---EPIDLFMIEIME-MKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCN 189 ++ ++ + ID+ +E + D+ ++RG++++ HP M++ +++ I+ + Sbjct: 145 VQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLD 204 Query: 190 VSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQ 249 SLEY+K E + E+ ++++ E ++I+ + II+LK V VI + Sbjct: 205 SSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDV---------VITE 255 Query: 250 KGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGH-AGLVYEY 308 KGI + L + I A+RR ++ + R+ ACG ++ ++L D +G AGL+ Sbjct: 256 KGISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIK 315 Query: 309 TLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGA 368 +G+E FTFI C +P++ T+L++G +K L++++ ++D ++ +N + D +VPG GA Sbjct: 316 KIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGA 375 Query: 369 VEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHS-E 427 E+A+A AL + ++ G Q +A A AL +IP+ L QN G L ++A+H+ E Sbjct: 376 SEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQE 435 Query: 428 SGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIM 477 + + GV+ TG + E+G+W+ VK Q + A +L +D+I+ Sbjct: 436 NCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIV 485 >gi|57863257 T-complex protein 1 isoform a [Homo sapiens] Length = 556 Score = 181 bits (459), Expect = 1e-45 Identities = 132/523 (25%), Positives = 250/523 (47%), Gaps = 78/523 (14%) Query: 23 NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLH----------------- 65 N+ AA + ++++++LGP G KMLV GD+ +T DG +L Sbjct: 21 NVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELAD 80 Query: 66 ----EMG------------------------LHPRIITEGFEAAKEKALQFLEEVKV--S 95 E+G +HP + G+ A ++A++++ E + + Sbjct: 81 LQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVNT 140 Query: 96 REMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQD------EPIDLFMIEIM 149 E+ R+ LI+ A+TS+ +K+ D VVD++LAIK D P++ + I+ Sbjct: 141 DELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVN--SVNIL 198 Query: 150 EMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAE 209 + +S+ ++ LI G L+ M KR+ +A I + SL+ K ++ E Sbjct: 199 KAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPE 258 Query: 210 EREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALR 269 + +++ + E ++R++KI+ V ++ GID L + G +A+R Sbjct: 259 KLDQIRQRESDITKERIQKILATGANV---------ILTTGGIDDMCLKYFVEAGAMAVR 309 Query: 270 RAKRRNMERLTLACGGVALNSFDDLSPD------CLGHAGLVYEYTLGEEKFTFIEKCNN 323 R +R+++R+ A G L++ +L + LG A V + + +++ I+ Sbjct: 310 RVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKA 369 Query: 324 PRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPS 383 S +++++G N +++ ++ D L VK ++ VVPG GAVE A++ L + S Sbjct: 370 RTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATS 429 Query: 384 VKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESG--------QLVGVD 435 + R QL + FA +LL+IP LA N+ D + + K++A H+E+ + +G+D Sbjct: 430 MGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLD 489 Query: 436 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMR 478 L+ G+P + GV++ VK + L T A IL +D++++ Sbjct: 490 LSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIK 532 >gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo sapiens] Length = 539 Score = 179 bits (455), Expect = 4e-45 Identities = 136/510 (26%), Positives = 245/510 (48%), Gaps = 65/510 (12%) Query: 23 NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEM--------------- 67 NISAA+ + D +RT+LGPKG KM+ G GD+ +T DG +L +M Sbjct: 37 NISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVELSK 96 Query: 68 ------------------------------GLHPRIITEGFEAAKEKALQFLEEVKVSRE 97 G+HP II+E F+ A EK ++ L ++ E Sbjct: 97 AQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIEILTDMSRPVE 156 Query: 98 M-DRETLIDVARTSLRTKVHAELADVLTEAVVDSILAI--KKQDEPIDLFMIEIMEMKHK 154 + DRETL++ A TSL +KV ++ + +L+ V++++ + +DL I+I++ Sbjct: 157 LSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGG 216 Query: 155 SETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKL 214 + D L+ GLVL + + RVE A I L KT++++ + +++ Sbjct: 217 TIDDCELVEGLVLTQKVSNSGIT-RVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRV 275 Query: 215 VKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGI-----DPFSLDALSKEGIVALR 269 ++ ER +I + VK+I K+ C V++ QK I +L L+K I+ ++ Sbjct: 276 LREERAYILNLVKQI---KKTGCN------VLLIQKSILRDALSDLALHFLNKMKIMVIK 326 Query: 270 RAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTL-GEEKFTFIEKCNNP-RSV 327 +R ++E + G + D + D LG A L E L G K I C +P ++V Sbjct: 327 DIEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGCASPGKTV 386 Query: 328 TLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGR 387 T++++G NK + + + ++ D L ++ + ++ G GA E+ +A L ++ ++ G Sbjct: 387 TIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGM 446 Query: 388 AQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVDLNTGEPMVAAEV 447 V+AFADA+ +IP LA+N+G + T+ +++ H++ + G+++ G E Sbjct: 447 ESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTAGINVRKGGISNILEE 506 Query: 448 GVWDNYCVKKQLLHSCTVIATNILLVDEIM 477 V V L T +IL +D+++ Sbjct: 507 LVVQPLLVSVSALTLATETVRSILKIDDVV 536 >gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo sapiens] Length = 543 Score = 179 bits (453), Expect = 7e-45 Identities = 130/518 (25%), Positives = 239/518 (46%), Gaps = 65/518 (12%) Query: 20 LAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLH-------------- 65 L NISA + + + +RT LGP+G K++V G G ++ DG +L Sbjct: 22 LVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGATILKLLDVVHPAAKTLVD 81 Query: 66 -------------------------------EMGLHPRIITEGFEAAKEKALQFLEEV-- 92 E GLHP+II F A + A+ ++E+ Sbjct: 82 IAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRAFRTATQLAVNKIKEIAV 141 Query: 93 ---KVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPIDLFMIEIM 149 K + R+ L A T+L +K+ ++ + VVD+++ + D+ + L MI I Sbjct: 142 TVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVMML---DDLLQLKMIGIK 198 Query: 150 EMKHKSETDTSLIRGLVLDHGARHPDMK---KRVEDAYILTCNVSLEYEKTEVNSGFFYK 206 +++ + D+ L+ G+ + + K+ + I NV LE + + N+ Sbjct: 199 KVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELKAEKDNAEIRVH 258 Query: 207 SAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIV 266 + E+ + +V AE + D+++KI KV V+++ I + + + Sbjct: 259 TVEDYQAIVDAEWNILYDKLEKIHHSGAKV---------VLSKLPIGDVATQYFADRDMF 309 Query: 267 ALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKFTFIEKCNNPRS 326 R +++R +ACGG S + LS D LG + E +G E++ F C ++ Sbjct: 310 CAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNFFTGCPKAKT 369 Query: 327 VTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKG 386 T +++G + + + + ++ D + V+ AI + VV G GA+E+ +++ L + ++ G Sbjct: 370 CTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPG 429 Query: 387 RAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVDLNTGEPMVAAE 446 + QL + A+A AL IIP+ L N+GFD L K++A H++ G GVD+N + E Sbjct: 430 KQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFE 489 Query: 447 VGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSL 484 VW+ V+ L + + A I+ VDE ++ S++ Sbjct: 490 AFVWEPAMVRINALTAASEAACLIVSVDETIKNPRSTV 527 >gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens] Length = 535 Score = 162 bits (410), Expect = 6e-40 Identities = 134/533 (25%), Positives = 243/533 (45%), Gaps = 69/533 (12%) Query: 1 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKL--TK 58 +A V A+ RA+ A + A + D++++ LGPKG K+L+S D L T Sbjct: 6 LAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTN 65 Query: 59 DGNVLLHEMG---------------------------------------------LHPRI 73 DG +L +G +HP+ Sbjct: 66 DGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQT 125 Query: 74 ITEGFEAAKEKALQFLEEVKVSREMD----RETLIDVARTSLRTKVHAELADVLTEAVVD 129 I G+ A + A + L V D R+ L+++A T+L +K+ D T+ V+ Sbjct: 126 IIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVE 185 Query: 130 SILAIKKQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDH--GARHPDMKKRVEDAYILT 187 ++L +K +L I I++ S D+ L G +LD G P KR+E+A IL Sbjct: 186 AVLRLKGSG---NLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQP---KRIENAKILI 239 Query: 188 CNVSLEYEKTEV-NSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVV 246 N ++ +K ++ S S + ++ AE++ ++++V++I LK + Sbjct: 240 ANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERI--LKHGIN-------CF 290 Query: 247 INQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVY 306 IN++ I + G++A+ A +ERL L GG ++FD LG L+ Sbjct: 291 INRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIE 350 Query: 307 EYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGA 366 E +GE+K + T++++G + L + + ++ D L + + D V G Sbjct: 351 EVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGG 410 Query: 367 GAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHS 426 G E+ MA A+ + G+ + ++++A AL ++P ++A N+G+D + + +++A HS Sbjct: 411 GCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHS 470 Query: 427 ESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRA 479 E G+D+ G A +G+ +++ VK+Q+L S A IL VD I++A Sbjct: 471 EGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKA 523 >gi|57863259 T-complex protein 1 isoform b [Homo sapiens] Length = 401 Score = 142 bits (357), Expect = 9e-34 Identities = 100/388 (25%), Positives = 191/388 (49%), Gaps = 31/388 (7%) Query: 111 LRTKVHAELADVLTEAVVDSILAIKKQD------EPIDLFMIEIMEMKHKSETDTSLIRG 164 + +K+ D VVD++LAIK D P++ + I++ +S+ ++ LI G Sbjct: 1 MSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVN--SVNILKAHGRSQMESMLISG 58 Query: 165 LVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIED 224 L+ M KR+ +A I + SL+ K ++ E+ +++ + E ++ Sbjct: 59 YALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKE 118 Query: 225 RVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACG 284 R++KI+ V ++ GID L + G +A+RR +R+++R+ A G Sbjct: 119 RIQKILATGANV---------ILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASG 169 Query: 285 GVALNSFDDLSPD------CLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHT 338 L++ +L + LG A V + + +++ I+ S +++++G N Sbjct: 170 ATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFM 229 Query: 339 LTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFADA 398 +++ ++ D L VK ++ VVPG GAVE A++ L + S+ R QL + FA + Sbjct: 230 CDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARS 289 Query: 399 LLIIPKVLAQNSGFDLQETLVKIQAEHSESG--------QLVGVDLNTGEPMVAAEVGVW 450 LL+IP LA N+ D + + K++A H+E+ + +G+DL+ G+P + GV+ Sbjct: 290 LLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVF 349 Query: 451 DNYCVKKQLLHSCTVIATNILLVDEIMR 478 + VK + L T A IL +D++++ Sbjct: 350 EPTIVKVKSLKFATEAAITILRIDDLIK 377 >gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Homo sapiens] Length = 339 Score = 133 bits (334), Expect = 4e-31 Identities = 83/307 (27%), Positives = 153/307 (49%), Gaps = 9/307 (2%) Query: 178 KRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVC 237 K+ + I NV LE + + N+ + E+ + +V AE + D+++KI KV Sbjct: 26 KKYHNPKIALLNVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKV- 84 Query: 238 GDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPD 297 V+++ I + + + R +++R +ACGG S + LS D Sbjct: 85 --------VLSKLPIGDVATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSAD 136 Query: 298 CLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAI 357 LG + E +G E++ F C ++ T +++G + + + + ++ D + V+ AI Sbjct: 137 VLGRCQVFEETQIGGERYNFFTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAI 196 Query: 358 DDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQET 417 + VV G GA+E+ +++ L + ++ G+ QL + A+A AL IIP+ L N+GFD Sbjct: 197 KNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNI 256 Query: 418 LVKIQAEHSESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIM 477 L K++A H++ G GVD+N + E VW+ V+ L + + A I+ VDE + Sbjct: 257 LNKLRARHAQGGTWYGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETI 316 Query: 478 RAGMSSL 484 + S++ Sbjct: 317 KNPRSTV 323 >gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo sapiens] Length = 548 Score = 129 bits (323), Expect = 8e-30 Identities = 120/514 (23%), Positives = 208/514 (40%), Gaps = 63/514 (12%) Query: 17 QAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEM--------- 67 + A+ NI A + L RT GP G KM+++ + +T D +L E+ Sbjct: 26 EEAVYRNIQACKELAQTTRTAYGPNGMNKMVINHLEKLFVTNDAATILRELEVQHPAAKM 85 Query: 68 ------------------------------------GLHPRIITEGFEAAKEKALQFLEE 91 GL + EG+E A KA + L Sbjct: 86 IVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVIEGYEIACRKAHEILPN 145 Query: 92 V---KVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPIDLFMIEI 148 + D + + + RTS+ +K + L + + + ++I ++ I + Sbjct: 146 LVCCSAKNLRDIDEVSSLLRTSIMSKQYGNEV-FLAKLIAQACVSIFPDSGHFNVDNIRV 204 Query: 149 MEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSA 208 ++ + +S++ G+V V+DA I + + TE K+A Sbjct: 205 CKILGSGISSSSVLHGMVFKKETEGDVTS--VKDAKIAVYSCPFDGMITETKGTVLIKTA 262 Query: 209 EEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVAL 268 EE K E ++ +VK I D+ VV K D +L +K I+ + Sbjct: 263 EELMNFSKGEENLMDAQVKAI--------ADTGANVVVTGGKVAD-MALHYANKYNIMLV 313 Query: 269 RRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKFTFIEKCNNPRSV- 327 R + ++ RL G AL + +GH VY +G+ + + ++ Sbjct: 314 RLNSKWDLRRLCKTVGATALPRLTPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAIS 373 Query: 328 TLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGR 387 T++++G + + I+ AV DG+ K D +VPG GA E+ +A+ + + + G Sbjct: 374 TIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGL 433 Query: 388 AQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVDLNTGEPMV--AA 445 Q ++ FA+A IP+ LA+NSG E + K+ A H E + VG+D+ P V Sbjct: 434 EQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGLDIEAEVPAVKDML 493 Query: 446 EVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRA 479 E G+ D Y K + T A +L VD+I+ A Sbjct: 494 EAGILDTYLGKYWAIKLATNAAVTVLRVDQIIMA 527 >gi|7657253 T-complex protein 1 [Homo sapiens] Length = 557 Score = 85.5 bits (210), Expect = 1e-16 Identities = 116/508 (22%), Positives = 195/508 (38%), Gaps = 59/508 (11%) Query: 20 LAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMGL-HPR------ 72 L +++A + L V+R GP G K LV+ G+ T +L + L HP Sbjct: 33 LLSSLAAVQTLASVIRPCYGPHGRQKFLVTMKGETVCTGCATAILRALELEHPAAWLLRE 92 Query: 73 -----------------IITEGFEAAKEKAL-------QFLEEVKVSREMDRETLIDVAR 108 ++TE E+ L Q E + TL +A Sbjct: 93 AGQTQAENSGDGTAFVVLLTEALLEQAEQLLKAGLPRPQLREAYATATAEVLATLPSLAI 152 Query: 109 TSLRT------KVHAEL-------ADVLTEAVVDSILAIKKQDEPIDLFMIEIMEMKHKS 155 SL +H+ + D LT+ V + AIK+ D + + + + Sbjct: 153 QSLGPLEDPSWALHSVMNTHTLSPMDHLTKLVAHACWAIKELDGSFKPERVGVCALPGGT 212 Query: 156 ETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLV 215 D+ L+ GL + G M + A + + S + + Sbjct: 213 LEDSCLLPGLAIS-GKLCGQMATVLSGARVALFACPFGPAHPNAPATARLSSPADLAQFS 271 Query: 216 KAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAKRRN 275 K + +E +V ++ V VV+ + +D +L K GIV ++ Sbjct: 272 KGSDQLLEKQVGQLAAAGINVA-------VVLGE--VDEETLTLADKYGIVVIQARSWME 322 Query: 276 MERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKFTFIE-KCNNPRSVTLLIKGP 334 + L+ L L P G VY LG+ E +C ++T++++G Sbjct: 323 IIYLSEVLDTPLLPRL--LPPQRPGKCQRVYRQELGDGLAVVFEWECTGTPALTVVLRGA 380 Query: 335 NKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQA 394 L + AV G+ A D ++PGAGA E+A+A+ L ++G + A Sbjct: 381 TTQGLRSAEQAVYHGIDAYFQLCQDPRLIPGAGATEMALAKMLSDKGSRLEGPSGPAFLA 440 Query: 395 FADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVDLNTGEPMVAAEVGVWDNYC 454 FA AL +PK LA+N+G + + + ++ H L+GV T + A+ GVWD Sbjct: 441 FAWALKYLPKTLAENAGLAVSDVMAEMSGVHQGGNLLMGV--GTEGIINVAQEGVWDTLI 498 Query: 455 VKKQLLHSCTVIATNILLVDEIMRAGMS 482 VK Q + + ++ VDEI+ A S Sbjct: 499 VKAQGFRAVAEVVLQLVTVDEIVVAKKS 526 >gi|41399285 chaperonin [Homo sapiens] Length = 573 Score = 45.4 bits (106), Expect = 1e-04 Identities = 110/546 (20%), Positives = 217/546 (39%), Gaps = 96/546 (17%) Query: 19 ALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMGLHPRIITEGF 78 A A+ + L D + +GPKG ++ G K+TKDG + + L + G Sbjct: 36 ARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGA 95 Query: 79 EAAKEKALQFLEEVK--------VSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDS 130 + ++ A EE ++R + +E +++ + ++ + VD+ Sbjct: 96 KLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVM-----LAVDA 150 Query: 131 ILA-IKKQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKK-------RVED 182 ++A +KKQ +P+ EI ++ S I ++ D MKK V+D Sbjct: 151 VIAELKKQSKPVTT-PEEIAQVATISANGDKEIGNIISDA------MKKVGRKGVITVKD 203 Query: 183 AYILTCNVSL----EYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKV-C 237 L + + ++++ ++ F S ++ + A E ++ I + + Sbjct: 204 GKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIVPALEI 263 Query: 238 GDSDKGFVVINQKGIDPFSLDALS----KEG--IVALRRA-----KRRNMERLTLACGGV 286 ++ + +VI + +D +L L K G +VA++ ++ ++ + +A GG Sbjct: 264 ANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGA 323 Query: 287 ALN------SFDDLSPDCLGHAGLVY-----------------------------EYTLG 311 + +D+ P LG G V + T Sbjct: 324 VFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTS 383 Query: 312 E-EKFTFIEKCNNPRSVTLLIK--GPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGA 368 E EK E+ ++K G + + + KD V D L A + A+++G V+ G G Sbjct: 384 EYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVL-GGGC 442 Query: 369 VEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSES 428 + AL P+ + + ++G++ L I +A+N+G + + KI SE Sbjct: 443 ALLRCIPALDSLTPANEDQ-KIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKIMQSSSE- 500 Query: 429 GQLVGVDLNTGEPMVAAEVGVWD-NYCVKKQLLHS---CTVIATNILLVDEIMR----AG 480 VG D G+ + E G+ D V+ LL + +++ T ++V EI + G Sbjct: 501 ---VGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPG 557 Query: 481 MSSLKG 486 M ++ G Sbjct: 558 MGAMGG 563 >gi|31542947 chaperonin [Homo sapiens] Length = 573 Score = 45.4 bits (106), Expect = 1e-04 Identities = 110/546 (20%), Positives = 217/546 (39%), Gaps = 96/546 (17%) Query: 19 ALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMGLHPRIITEGF 78 A A+ + L D + +GPKG ++ G K+TKDG + + L + G Sbjct: 36 ARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGA 95 Query: 79 EAAKEKALQFLEEVK--------VSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDS 130 + ++ A EE ++R + +E +++ + ++ + VD+ Sbjct: 96 KLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVM-----LAVDA 150 Query: 131 ILA-IKKQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKK-------RVED 182 ++A +KKQ +P+ EI ++ S I ++ D MKK V+D Sbjct: 151 VIAELKKQSKPVTT-PEEIAQVATISANGDKEIGNIISDA------MKKVGRKGVITVKD 203 Query: 183 AYILTCNVSL----EYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKV-C 237 L + + ++++ ++ F S ++ + A E ++ I + + Sbjct: 204 GKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIVPALEI 263 Query: 238 GDSDKGFVVINQKGIDPFSLDALS----KEG--IVALRRA-----KRRNMERLTLACGGV 286 ++ + +VI + +D +L L K G +VA++ ++ ++ + +A GG Sbjct: 264 ANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGA 323 Query: 287 ALN------SFDDLSPDCLGHAGLVY-----------------------------EYTLG 311 + +D+ P LG G V + T Sbjct: 324 VFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTS 383 Query: 312 E-EKFTFIEKCNNPRSVTLLIK--GPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGA 368 E EK E+ ++K G + + + KD V D L A + A+++G V+ G G Sbjct: 384 EYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVL-GGGC 442 Query: 369 VEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSES 428 + AL P+ + + ++G++ L I +A+N+G + + KI SE Sbjct: 443 ALLRCIPALDSLTPANEDQ-KIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKIMQSSSE- 500 Query: 429 GQLVGVDLNTGEPMVAAEVGVWD-NYCVKKQLLHS---CTVIATNILLVDEIMR----AG 480 VG D G+ + E G+ D V+ LL + +++ T ++V EI + G Sbjct: 501 ---VGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPG 557 Query: 481 MSSLKG 486 M ++ G Sbjct: 558 MGAMGG 563 >gi|21735548 centrosomal protein 2 [Homo sapiens] Length = 2442 Score = 36.2 bits (82), Expect = 0.069 Identities = 38/153 (24%), Positives = 66/153 (43%), Gaps = 20/153 (13%) Query: 82 KEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPI 141 +E+ L E E DRET +V L + E D + E+ + +KKQ + Sbjct: 1499 REQKLTVQREQIRELEKDRETQRNVLEHQL---LELEKKDQMIESQRGQVQDLKKQLVTL 1555 Query: 142 DLFMIEIMEMKHKSETDTSLIRGLVLDHGARHP----------DMKKRVEDAYILTCNVS 191 + +E+ E HK E LI+ L G R D+++R ++ S Sbjct: 1556 ECLALELEENHHKMECQQKLIKEL---EGQRETQRVALTHLTLDLEERSQELQA----QS 1608 Query: 192 LEYEKTEVNSGFFYKSAEEREKLVKAERKFIED 224 + E +S + +ER++ VK++R+ IE+ Sbjct: 1609 SQIHDLESHSTVLARELQERDQEVKSQREQIEE 1641 >gi|4503509 eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa [Homo sapiens] Length = 1382 Score = 34.7 bits (78), Expect = 0.20 Identities = 47/197 (23%), Positives = 81/197 (41%), Gaps = 43/197 (21%) Query: 72 RIITEGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAEL-ADVLTEAVVDS 130 R+ E E KE+ LQ E++K ++ RE L + +T L K ++ + L E D Sbjct: 611 RLRQEAKEREKERILQEHEQIK--KKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDF 668 Query: 131 ILA----------------IKKQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHP 174 I+A +K Q++ ID F + K + LI+ + + Sbjct: 669 IMAKQVEQLEKEKKELQERLKNQEKKIDYFE------RAKRLEEIPLIKSAYEEQRIKDM 722 Query: 175 DMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEER----------------EKLVKAE 218 D+ ++ E+ I T + LE EK + + E+R EKL + E Sbjct: 723 DLWEQQEEERITT--MQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFE 780 Query: 219 RKFIEDRVKKIIELKRK 235 + E+R ++ E KR+ Sbjct: 781 ERLAEERHNRLEERKRQ 797 >gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1 [Homo sapiens] Length = 3259 Score = 33.9 bits (76), Expect = 0.34 Identities = 67/321 (20%), Positives = 135/321 (42%), Gaps = 47/321 (14%) Query: 61 NVLLHEMGLHPRIITEGFEAAKEKALQFLEEVKVS------REMDRETLIDVARTSLRTK 114 N L+ E + + F A E+ Q L +VK R ++ +++A + + Sbjct: 722 NQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRR 781 Query: 115 VHAELA----DVLTEAVVDSILAIKKQDEPIDLFMIEIMEMKHKSETDTSLIRGL----- 165 + E ++LTE + + K +D I++ E+ +++ + ++LIR L Sbjct: 782 LDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQ 841 Query: 166 -----VLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERK 220 VL+ R + +VE+ LE K + + E+++ V+ ++ Sbjct: 842 NKESEVLEGAERVRHISSKVEELSQALSQKELEITKMD-------QLLLEKKRDVETLQQ 894 Query: 221 FIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDA---LSKEGIVALRR---AKRR 274 IE++ +++ E+ + + V +N+ + FSL KE + L R AK+ Sbjct: 895 TIEEKDQQVTEISFSM----TEKMVQLNE---EKFSLGVEIKTLKEQLNLLSRAEEAKKE 947 Query: 275 NMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGP 334 +E G+ N +D++SP AG + + L + +F ++K N R L Sbjct: 948 QVEEDNEVSSGLKQN-YDEMSP-----AGQISKEEL-QHEFDLLKKENEQRKRKLQAALI 1000 Query: 335 NKHTLTQIKDAVRDGLRAVKN 355 N+ L Q + + L +K+ Sbjct: 1001 NRKELLQRVSRLEEELANLKD 1021 >gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] Length = 4024 Score = 32.7 bits (73), Expect = 0.76 Identities = 48/215 (22%), Positives = 92/215 (42%), Gaps = 44/215 (20%) Query: 79 EAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVD----SILAI 134 +A + A +FLEE+++S E+ R+ ID+ ++ H D+ V+ + + Sbjct: 2507 DALQAVASRFLEEIEMSEEI-RDGCIDMCKS-----FHTSTIDLSKSFFVELQRYNYVTP 2560 Query: 135 KKQDEPIDLFMI-------EIMEMK-------HKSETDTSLIRGLVLDHGARHPDMK--- 177 E I F + E+M+MK K ++ +S + + ++ A HP +K Sbjct: 2561 TSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQLKVAS 2620 Query: 178 KRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVC 237 K V++ I+ S+E KT EK+VKA+ ++ +K + C Sbjct: 2621 KEVDEMMIMIEKESVEVAKT--------------EKIVKADETIANEQAMASKAIKDE-C 2665 Query: 238 GDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAK 272 G + I + + +LD L+ + I ++ K Sbjct: 2666 DADLAGALPILESAL--AALDTLTAQDITVVKSMK 2698 >gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 32.7 bits (73), Expect = 0.76 Identities = 33/148 (22%), Positives = 71/148 (47%), Gaps = 5/148 (3%) Query: 93 KVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPIDLFM-IEIMEM 151 K+ R+++ TL A + K HA+ L E + D++ +K++ E M +EI ++ Sbjct: 1179 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQI-DNLQRVKQKLEKEKSEMKMEIDDL 1237 Query: 152 KHKSETDTSL---IRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSA 208 ET + + + + ++K + E+ L +++ + + + SG F + Sbjct: 1238 ASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQL 1297 Query: 209 EEREKLVKAERKFIEDRVKKIIELKRKV 236 +E+E LV + + ++I ELKR++ Sbjct: 1298 DEKEALVSQLSRGKQAFTQQIEELKRQL 1325 >gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 32.7 bits (73), Expect = 0.76 Identities = 33/148 (22%), Positives = 71/148 (47%), Gaps = 5/148 (3%) Query: 93 KVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPIDLFM-IEIMEM 151 K+ R+++ TL A + K HA+ L E + D++ +K++ E M +EI ++ Sbjct: 1179 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQI-DNLQRVKQKLEKEKSEMKMEIDDL 1237 Query: 152 KHKSETDTSL---IRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSA 208 ET + + + + ++K + E+ L +++ + + + SG F + Sbjct: 1238 ASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQL 1297 Query: 209 EEREKLVKAERKFIEDRVKKIIELKRKV 236 +E+E LV + + ++I ELKR++ Sbjct: 1298 DEKEALVSQLSRGKQAFTQQIEELKRQL 1325 >gi|70980531 GGA binding partner [Homo sapiens] Length = 441 Score = 32.7 bits (73), Expect = 0.76 Identities = 40/174 (22%), Positives = 82/174 (47%), Gaps = 25/174 (14%) Query: 73 IITEGFEAAKEK-ALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSI 131 ++ +GF KE+ A+ F + K +E ++ L D+ + H L+ ++ E Sbjct: 168 VLEKGFLKEKEQEAISFQDRYKELQEKHKQELEDMRKAG-----HEALSIIVDEYKALLQ 222 Query: 132 LAIKKQDEPIDLFMIEIMEMK-HKSETDTSLIRGLVLDHGARHPDM-KKRVEDAYILTCN 189 ++K+Q E I+ I +E + HK E + +L+ ++ K+++++A I Sbjct: 223 SSVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQRLLEMLDTEKELLKEKIKEALI---- 278 Query: 190 VSLEYEKTEVNSGFFYKSAEE-----REKLVKA---ERKFIEDRVKKIIELKRK 235 ++++ K EE +E LV A E++ ++D V K++E +RK Sbjct: 279 -----QQSQEQKEILEKCLEEERQRNKEALVSAAKLEKEAVKDAVLKVVEEERK 327 >gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo sapiens] Length = 638 Score = 32.3 bits (72), Expect = 0.99 Identities = 30/165 (18%), Positives = 76/165 (46%), Gaps = 21/165 (12%) Query: 83 EKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPID 142 EK L+++EE+ + + + +D+A+ K + L +++ ++I+ + KQ E ++ Sbjct: 145 EKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLN 204 Query: 143 LFMIEIMEMKHKSETD-------------TSLIRGLVLDHGARHPDMKKRVEDAYILTCN 189 + +++E + + + +L + +L+ R +K ++ Sbjct: 205 V-KCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQID------ 257 Query: 190 VSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKR 234 SL ++ E++S K +E++VK + F E+ + + EL + Sbjct: 258 -SLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDK 301 >gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo sapiens] Length = 725 Score = 32.3 bits (72), Expect = 0.99 Identities = 30/165 (18%), Positives = 76/165 (46%), Gaps = 21/165 (12%) Query: 83 EKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPID 142 EK L+++EE+ + + + +D+A+ K + L +++ ++I+ + KQ E ++ Sbjct: 232 EKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLN 291 Query: 143 LFMIEIMEMKHKSETD-------------TSLIRGLVLDHGARHPDMKKRVEDAYILTCN 189 + +++E + + + +L + +L+ R +K ++ Sbjct: 292 V-KCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQID------ 344 Query: 190 VSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKR 234 SL ++ E++S K +E++VK + F E+ + + EL + Sbjct: 345 -SLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDK 388 >gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo sapiens] Length = 709 Score = 32.3 bits (72), Expect = 0.99 Identities = 30/165 (18%), Positives = 76/165 (46%), Gaps = 21/165 (12%) Query: 83 EKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPID 142 EK L+++EE+ + + + +D+A+ K + L +++ ++I+ + KQ E ++ Sbjct: 216 EKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLN 275 Query: 143 LFMIEIMEMKHKSETD-------------TSLIRGLVLDHGARHPDMKKRVEDAYILTCN 189 + +++E + + + +L + +L+ R +K ++ Sbjct: 276 V-KCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQID------ 328 Query: 190 VSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKR 234 SL ++ E++S K +E++VK + F E+ + + EL + Sbjct: 329 -SLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDK 372 >gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo sapiens] Length = 724 Score = 32.3 bits (72), Expect = 0.99 Identities = 30/165 (18%), Positives = 76/165 (46%), Gaps = 21/165 (12%) Query: 83 EKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPID 142 EK L+++EE+ + + + +D+A+ K + L +++ ++I+ + KQ E ++ Sbjct: 231 EKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLN 290 Query: 143 LFMIEIMEMKHKSETD-------------TSLIRGLVLDHGARHPDMKKRVEDAYILTCN 189 + +++E + + + +L + +L+ R +K ++ Sbjct: 291 V-KCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQID------ 343 Query: 190 VSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKR 234 SL ++ E++S K +E++VK + F E+ + + EL + Sbjct: 344 -SLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDK 387 >gi|114155142 nuclear pore complex-associated protein TPR [Homo sapiens] Length = 2363 Score = 32.3 bits (72), Expect = 0.99 Identities = 36/151 (23%), Positives = 75/151 (49%), Gaps = 11/151 (7%) Query: 81 AKEKALQFLEEVKVSREMDRETLIDVART-SLRTKVHAELADVLTEAVVDSILAIKKQDE 139 ++E+ L+ L ++ +E+ ET +VA+ SLR + EL + + + DS+ A +++ + Sbjct: 1192 SQEQILEILRFIRREKEI-AETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQ 1250 Query: 140 PIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVE-DAYILTCNV-SLEYEKT 197 M + E+ K+ET +V++ + K+R+E D + V LE + Sbjct: 1251 VTAKTMAQHEELMKKTET-----MNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDIL 1305 Query: 198 EVNSGFFYKSAEEREKLVKAERKFIEDRVKK 228 + E+ +++AE+K +E+ VK+ Sbjct: 1306 PLQEA--NAELSEKSGMLQAEKKLLEEDVKR 1334 >gi|10863929 ribonuclease L [Homo sapiens] Length = 741 Score = 32.0 bits (71), Expect = 1.3 Identities = 66/253 (26%), Positives = 103/253 (40%), Gaps = 42/253 (16%) Query: 22 VNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTK---DGNVLLHEMGLHPRIITEGF 78 V + G VLR G T +L + AG +KL K ++E + T Sbjct: 75 VELLLRHGADPVLRKKNG--ATPFILAAIAGSVKLLKLFLSKGADVNECDFYG--FTAFM 130 Query: 79 EAA---KEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK 135 EAA K KAL+FL + + + R+T D R LR L D + V+ +L I Sbjct: 131 EAAVYGKVKALKFLYKRGANVNLRRKTKEDQER--LRKGGATALMDAAEKGHVE-VLKIL 187 Query: 136 KQDEPIDLFMIEIM-------EMKHKSETDTSLIRGLVLDHGARHPDMKKR--------- 179 + D+ + M + ++D I L+LDHGA D+ R Sbjct: 188 LDEMGADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHGA---DVNVRGERGKTPLI 244 Query: 180 --VEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVC 237 VE ++ LE E E+N ++ + L+ A +E ++KKI EL K Sbjct: 245 LAVEKKHLGLVQRLLEQEHIEIND----TDSDGKTALLLA----VELKLKKIAELLCKRG 296 Query: 238 GDSDKGFVVINQK 250 +D G +V+ + Sbjct: 297 ASTDCGDLVMTAR 309 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.134 0.373 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,494,482 Number of Sequences: 37866 Number of extensions: 624740 Number of successful extensions: 1802 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 18 Number of HSP's successfully gapped in prelim test: 30 Number of HSP's that attempted gapping in prelim test: 1734 Number of HSP's gapped (non-prelim): 75 length of query: 486 length of database: 18,247,518 effective HSP length: 106 effective length of query: 380 effective length of database: 14,233,722 effective search space: 5408814360 effective search space used: 5408814360 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.